Guide to the Human Genome
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Search of human proteins with 169166402

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
         (220 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]                455   e-128
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]                453   e-128
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]                453   e-128
gi|162417973 claudin 22 [Homo sapiens]                                399   e-112
gi|157820127 claudin-like [Homo sapiens]                              229   1e-60
gi|153792768 claudin 6 [Homo sapiens]                                 131   4e-31
gi|153792186 claudin 7 [Homo sapiens]                                 129   3e-30
gi|10863887 claudin 1 [Homo sapiens]                                  126   1e-29
gi|40788011 claudin 8 [Homo sapiens]                                  126   2e-29
gi|11141861 claudin 9 [Homo sapiens]                                  124   8e-29
gi|195947374 claudin 5 [Homo sapiens]                                 119   3e-27
gi|195947372 claudin 5 [Homo sapiens]                                 119   3e-27
gi|4502877 claudin 4 [Homo sapiens]                                   118   5e-27
gi|183979973 claudin 19 isoform a [Homo sapiens]                      118   5e-27
gi|183979975 claudin 19 isoform b [Homo sapiens]                      118   5e-27
gi|4502875 claudin 3 [Homo sapiens]                                   115   4e-26
gi|225703142 claudin 14 [Homo sapiens]                                114   9e-26
gi|21536294 claudin 14 [Homo sapiens]                                 114   9e-26
gi|225703138 claudin 14 [Homo sapiens]                                114   9e-26
gi|6912314 claudin 14 [Homo sapiens]                                  114   9e-26
gi|225703140 claudin 14 [Homo sapiens]                                114   9e-26
gi|50345279 claudin 18 isoform 2 [Homo sapiens]                       112   2e-25
gi|7705961 claudin 18 isoform 1 [Homo sapiens]                        112   2e-25
gi|6912316 claudin 17 [Homo sapiens]                                  107   6e-24
gi|9966781 claudin 2 [Homo sapiens]                                   102   3e-22
gi|5921465 claudin 10 isoform b [Homo sapiens]                        100   1e-21
gi|7656981 claudin 15 [Homo sapiens]                                   97   1e-20
gi|47716519 claudin 20 [Homo sapiens]                                  83   2e-16
gi|10938016 claudin 11 [Homo sapiens]                                  75   6e-14
gi|33598916 claudin 10 isoform a [Homo sapiens]                        72   3e-13

>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score =  455 bits (1170), Expect = e-128
 Identities = 220/220 (100%), Positives = 220/220 (100%)

Query: 1   MALIFRTAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60
           MALIFRTAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV
Sbjct: 1   MALIFRTAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60

Query: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120
           GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI
Sbjct: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120

Query: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180
           LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG
Sbjct: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180

Query: 181 CLLNCAACSSHAPLALGHYAVAQMQTQCPYLEDGTADPQV 220
           CLLNCAACSSHAPLALGHYAVAQMQTQCPYLEDGTADPQV
Sbjct: 181 CLLNCAACSSHAPLALGHYAVAQMQTQCPYLEDGTADPQV 220


>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score =  453 bits (1166), Expect = e-128
 Identities = 219/220 (99%), Positives = 219/220 (99%)

Query: 1   MALIFRTAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60
           MALIFRTAMQSVGLLLS LGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV
Sbjct: 1   MALIFRTAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60

Query: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120
           GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI
Sbjct: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120

Query: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180
           LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG
Sbjct: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180

Query: 181 CLLNCAACSSHAPLALGHYAVAQMQTQCPYLEDGTADPQV 220
           CLLNCAACSSHAPLALGHYAVAQMQTQCPYLEDGTADPQV
Sbjct: 181 CLLNCAACSSHAPLALGHYAVAQMQTQCPYLEDGTADPQV 220


>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score =  453 bits (1166), Expect = e-128
 Identities = 219/220 (99%), Positives = 219/220 (99%)

Query: 1   MALIFRTAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60
           MALIFRTAMQSVGLLLS LGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV
Sbjct: 1   MALIFRTAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60

Query: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120
           GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI
Sbjct: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120

Query: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180
           LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG
Sbjct: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180

Query: 181 CLLNCAACSSHAPLALGHYAVAQMQTQCPYLEDGTADPQV 220
           CLLNCAACSSHAPLALGHYAVAQMQTQCPYLEDGTADPQV
Sbjct: 181 CLLNCAACSSHAPLALGHYAVAQMQTQCPYLEDGTADPQV 220


>gi|162417973 claudin 22 [Homo sapiens]
          Length = 220

 Score =  399 bits (1026), Expect = e-112
 Identities = 192/212 (90%), Positives = 198/212 (93%)

Query: 1   MALIFRTAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60
           MAL+FRT  Q  G+ LSLLGW+LS +T YLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV
Sbjct: 1   MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60

Query: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120
           GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI
Sbjct: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120

Query: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180
           LGGILSWASG+TALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG
Sbjct: 121 LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180

Query: 181 CLLNCAACSSHAPLALGHYAVAQMQTQCPYLE 212
           CLL+CAACSSHAPLA GHYAVAQ Q     LE
Sbjct: 181 CLLHCAACSSHAPLASGHYAVAQTQDHHQELE 212


>gi|157820127 claudin-like [Homo sapiens]
          Length = 229

 Score =  229 bits (584), Expect = 1e-60
 Identities = 108/188 (57%), Positives = 137/188 (72%)

Query: 1   MALIFRTAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60
           MA  FR  +Q  GLLLSLLGW+ S +TT LP WK LNL+LNEME W MG+W+ CV +EEV
Sbjct: 1   MAWSFRAKVQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWIMGIWEVCVDREEV 60

Query: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120
              CK F+SFL+LP EL+V+RILM  S+GLG LGLL+  FG +C +    +   KRRL +
Sbjct: 61  ATVCKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGL 120

Query: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180
           LG  L  ++  T L+PVSWVAH T+Q+FWD+++PD +PRWEFG AL+LGW AG+ L LGG
Sbjct: 121 LGRTLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGG 180

Query: 181 CLLNCAAC 188
            LL  +AC
Sbjct: 181 LLLIFSAC 188


>gi|153792768 claudin 6 [Homo sapiens]
          Length = 220

 Score =  131 bits (330), Expect = 4e-31
 Identities = 79/212 (37%), Positives = 118/212 (55%), Gaps = 7/212 (3%)

Query: 9   MQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTM---GLWQTCVIQEEVGMQCK 65
           MQ +G++L+LLGW+  +++  LP WK      N +    +   GLW +CV+Q    MQCK
Sbjct: 6   MQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCK 65

Query: 66  DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
            +DS LALP +L+ +R L  ++  +   GLLV   G  C    E ++D K RL++  GI+
Sbjct: 66  VYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVE-EKDSKARLVLTSGIV 124

Query: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
              SG+  L+PV W AH  +++F++  V +   R E G +L+LGW A   LLLGG LL C
Sbjct: 125 FVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKR-ELGASLYLGWAASGLLLLGGGLL-C 182

Query: 186 AACSSHAPLALGHYAVAQMQTQCPYLEDGTAD 217
             C S       HY +A+  T  P +  G ++
Sbjct: 183 CTCPSGGSQGPSHY-MARYSTSAPAISRGPSE 213


>gi|153792186 claudin 7 [Homo sapiens]
          Length = 211

 Score =  129 bits (323), Expect = 3e-30
 Identities = 66/183 (36%), Positives = 106/183 (57%), Gaps = 4/183 (2%)

Query: 7   TAMQSVGLLLSLLGWILSIITTYLPHWKNLNL---DLNEMENWTMGLWQTCVIQEEVGMQ 63
           + +Q +G  ++LLGW+  +  T +P W+  +    ++   +    GLW  CV Q    M 
Sbjct: 4   SGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMS 63

Query: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
           CK +DS LAL A L+ +R LM +S  LGFL + V+  G+ C R G   +  K R+ + GG
Sbjct: 64  CKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGG 123

Query: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
           I+   +G+ ALV  SW  H+ V +F++  +P  + ++EFG A+F+GW     ++LGG LL
Sbjct: 124 IIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNI-KYEFGPAIFIGWAGSALVILGGALL 182

Query: 184 NCA 186
           +C+
Sbjct: 183 SCS 185


>gi|10863887 claudin 1 [Homo sapiens]
          Length = 211

 Score =  126 bits (317), Expect = 1e-29
 Identities = 67/181 (37%), Positives = 104/181 (57%), Gaps = 4/181 (2%)

Query: 9   MQSVGLLLSLLGWILSIITTYLPHWKNLNL---DLNEMENWTMGLWQTCVIQEEVGMQCK 65
           +Q +G +L+ LGWI +I++T LP W+  +    ++   +    GLW +CV Q    +QCK
Sbjct: 6   LQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCK 65

Query: 66  DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
            FDS L L + L+ +R LM +   LG + + V+  G+ C++  E     K R+ ++GG +
Sbjct: 66  VFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAI 125

Query: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
              +G+  LV  +W  ++ VQEF+D   P    R+EFG+ALF GW A    LLGG LL C
Sbjct: 126 FLLAGLAILVATAWYGNRIVQEFYDPMTP-VNARYEFGQALFTGWAAASLCLLGGALLCC 184

Query: 186 A 186
           +
Sbjct: 185 S 185


>gi|40788011 claudin 8 [Homo sapiens]
          Length = 225

 Score =  126 bits (316), Expect = 2e-29
 Identities = 69/216 (31%), Positives = 115/216 (53%), Gaps = 5/216 (2%)

Query: 8   AMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEM---ENWTMGLWQTCVIQEEVGMQC 64
           A++  GL L  +G + ++  T +P W+      N +   EN+  GLW  CV Q  + MQC
Sbjct: 5   ALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANIRMQC 64

Query: 65  KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
           K +DS LAL  +L+ +R LM  ++ + FL  +++  G+ C R       +K  +L+  GI
Sbjct: 65  KIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILLTAGI 124

Query: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLN 184
           +   +G+  L+PVSWVA+  +++F++ ++ +   + E GEAL+LGW   L L++GG L  
Sbjct: 125 IFIITGMVVLIPVSWVANAIIRDFYN-SIVNVAQKRELGEALYLGWTTALVLIVGGALFC 183

Query: 185 CAACSSHAPLALGHYAVAQMQTQCPYLEDGTADPQV 220
           C  C +    +  +   +   TQ  Y   G   P V
Sbjct: 184 CVFCCNEKSSSYRYSIPSHRTTQKSY-HTGKKSPSV 218


>gi|11141861 claudin 9 [Homo sapiens]
          Length = 217

 Score =  124 bits (310), Expect = 8e-29
 Identities = 68/182 (37%), Positives = 107/182 (58%), Gaps = 5/182 (2%)

Query: 7   TAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTM---GLWQTCVIQEEVGMQ 63
           T ++ +G+ L++LGW+ ++++  LP WK      N +    +   GLW +CV+Q    MQ
Sbjct: 4   TGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQ 63

Query: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
           CK +DS LALP +L+ +R L  ++  L  LGLLV+  G  C    E +   K R+++  G
Sbjct: 64  CKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDE-GAKARIVLTAG 122

Query: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
           ++   +GI  L+PV W AH  +Q+F++  V + + R E G +L+LGW A   L+LGG LL
Sbjct: 123 VILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKR-ELGASLYLGWAAAALLMLGGGLL 181

Query: 184 NC 185
            C
Sbjct: 182 CC 183


>gi|195947374 claudin 5 [Homo sapiens]
          Length = 303

 Score =  119 bits (297), Expect = 3e-27
 Identities = 72/183 (39%), Positives = 105/183 (57%), Gaps = 5/183 (2%)

Query: 8   AMQSVGLLLSLLGWILSIITTYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64
           A++ +GL+L L+GW   I+   LP W+    LD N +   T   GLW +CV+Q    MQC
Sbjct: 90  ALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQC 149

Query: 65  KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
           K +DS LAL  E++ +R L   +  L F+ L V+  G  C     +    K R+ + GG+
Sbjct: 150 KVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKARVALTGGV 208

Query: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLN 184
           L    G+ ALVP+ W A+  V+EF+D +VP    ++E G AL++GW A   L++GGCLL 
Sbjct: 209 LYLFCGLLALVPLCWFANIVVREFYDPSVP-VSQKYELGAALYIGWAATALLMVGGCLLC 267

Query: 185 CAA 187
           C A
Sbjct: 268 CGA 270


>gi|195947372 claudin 5 [Homo sapiens]
          Length = 303

 Score =  119 bits (297), Expect = 3e-27
 Identities = 72/183 (39%), Positives = 105/183 (57%), Gaps = 5/183 (2%)

Query: 8   AMQSVGLLLSLLGWILSIITTYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64
           A++ +GL+L L+GW   I+   LP W+    LD N +   T   GLW +CV+Q    MQC
Sbjct: 90  ALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQC 149

Query: 65  KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
           K +DS LAL  E++ +R L   +  L F+ L V+  G  C     +    K R+ + GG+
Sbjct: 150 KVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKARVALTGGV 208

Query: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLN 184
           L    G+ ALVP+ W A+  V+EF+D +VP    ++E G AL++GW A   L++GGCLL 
Sbjct: 209 LYLFCGLLALVPLCWFANIVVREFYDPSVP-VSQKYELGAALYIGWAATALLMVGGCLLC 267

Query: 185 CAA 187
           C A
Sbjct: 268 CGA 270


>gi|4502877 claudin 4 [Homo sapiens]
          Length = 209

 Score =  118 bits (295), Expect = 5e-27
 Identities = 67/180 (37%), Positives = 106/180 (58%), Gaps = 5/180 (2%)

Query: 9   MQSVGLLLSLLGWILSIITTYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQCK 65
           +Q +G+ L++LGW+  ++   LP W+    +  N + + T+  GLW  CV+Q    MQCK
Sbjct: 6   LQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCK 65

Query: 66  DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
            +DS LALP +L+ +R L+ +S  +  LG+L+S  G  C    E +   K + +I+ G++
Sbjct: 66  VYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDE-SAKAKTMIVAGVV 124

Query: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
              +G+  +VPVSW AH  +Q+F++  V     R E G +L++GW A   LLLGG LL C
Sbjct: 125 FLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKR-EMGASLYVGWAASGLLLLGGGLLCC 183


>gi|183979973 claudin 19 isoform a [Homo sapiens]
          Length = 224

 Score =  118 bits (295), Expect = 5e-27
 Identities = 68/190 (35%), Positives = 102/190 (53%), Gaps = 4/190 (2%)

Query: 7   TAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWT---MGLWQTCVIQEEVGMQ 63
           + +Q +G  L+L GW+  I +T LP WK  +   + +        GLW +C  Q    +Q
Sbjct: 4   SGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQ 63

Query: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
           CK +DS LAL   ++ +R LM ++  LGF+ +++S  G+ C R+G+S    K R+ I GG
Sbjct: 64  CKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGG 123

Query: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
            L   +G+  L  VSW A    QEF++ + P    R+EFG ALF+GW +    +LGG  L
Sbjct: 124 ALFILAGLCTLTAVSWYATLVTQEFFNPSTP-VNARYEFGPALFVGWASAGLAVLGGSFL 182

Query: 184 NCAACSSHAP 193
            C       P
Sbjct: 183 CCTCPEPERP 192


>gi|183979975 claudin 19 isoform b [Homo sapiens]
          Length = 211

 Score =  118 bits (295), Expect = 5e-27
 Identities = 68/190 (35%), Positives = 102/190 (53%), Gaps = 4/190 (2%)

Query: 7   TAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWT---MGLWQTCVIQEEVGMQ 63
           + +Q +G  L+L GW+  I +T LP WK  +   + +        GLW +C  Q    +Q
Sbjct: 4   SGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQ 63

Query: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
           CK +DS LAL   ++ +R LM ++  LGF+ +++S  G+ C R+G+S    K R+ I GG
Sbjct: 64  CKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGG 123

Query: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
            L   +G+  L  VSW A    QEF++ + P    R+EFG ALF+GW +    +LGG  L
Sbjct: 124 ALFILAGLCTLTAVSWYATLVTQEFFNPSTP-VNARYEFGPALFVGWASAGLAVLGGSFL 182

Query: 184 NCAACSSHAP 193
            C       P
Sbjct: 183 CCTCPEPERP 192


>gi|4502875 claudin 3 [Homo sapiens]
          Length = 220

 Score =  115 bits (287), Expect = 4e-26
 Identities = 64/181 (35%), Positives = 102/181 (56%), Gaps = 5/181 (2%)

Query: 9   MQSVGLLLSLLGWILSIITTYLPHWKN---LNLDLNEMENWTMGLWQTCVIQEEVGMQCK 65
           ++  G  L++LGW+ +I+   LP W+    +  ++   +N   GLW  CV+Q    MQCK
Sbjct: 5   LEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCK 64

Query: 66  DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
            +DS LALP +L+ +R L+ ++  L   GLLV+  G  C    +     K ++ I+ G+L
Sbjct: 65  VYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDD-TAKAKITIVAGVL 123

Query: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
              + +  LVPVSW A+  +++F++  VP+   R E G  L++GW A    LLGG LL C
Sbjct: 124 FLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKR-EMGAGLYVGWAAAALQLLGGALLCC 182

Query: 186 A 186
           +
Sbjct: 183 S 183


>gi|225703142 claudin 14 [Homo sapiens]
          Length = 239

 Score =  114 bits (284), Expect = 9e-26
 Identities = 67/190 (35%), Positives = 105/190 (55%), Gaps = 6/190 (3%)

Query: 7   TAMQSVGLLLSLLGWILSIITTYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63
           TA+Q +G LLS LG + ++ITT LPHW+   ++  ++    ++  GLW  CV       Q
Sbjct: 4   TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63

Query: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
           C+ + S LALP +L+ +R LM +S  L  +    +  G+ C R  +     K    ILGG
Sbjct: 64  CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122

Query: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
            L   +G+  +V VSW  +  VQ F++  +P  + ++E G+AL+LG+ +    L+GG LL
Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181

Query: 184 NCAACSSHAP 193
            C +C   AP
Sbjct: 182 -CLSCQDEAP 190


>gi|21536294 claudin 14 [Homo sapiens]
          Length = 239

 Score =  114 bits (284), Expect = 9e-26
 Identities = 67/190 (35%), Positives = 105/190 (55%), Gaps = 6/190 (3%)

Query: 7   TAMQSVGLLLSLLGWILSIITTYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63
           TA+Q +G LLS LG + ++ITT LPHW+   ++  ++    ++  GLW  CV       Q
Sbjct: 4   TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63

Query: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
           C+ + S LALP +L+ +R LM +S  L  +    +  G+ C R  +     K    ILGG
Sbjct: 64  CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122

Query: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
            L   +G+  +V VSW  +  VQ F++  +P  + ++E G+AL+LG+ +    L+GG LL
Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181

Query: 184 NCAACSSHAP 193
            C +C   AP
Sbjct: 182 -CLSCQDEAP 190


>gi|225703138 claudin 14 [Homo sapiens]
          Length = 239

 Score =  114 bits (284), Expect = 9e-26
 Identities = 67/190 (35%), Positives = 105/190 (55%), Gaps = 6/190 (3%)

Query: 7   TAMQSVGLLLSLLGWILSIITTYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63
           TA+Q +G LLS LG + ++ITT LPHW+   ++  ++    ++  GLW  CV       Q
Sbjct: 4   TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63

Query: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
           C+ + S LALP +L+ +R LM +S  L  +    +  G+ C R  +     K    ILGG
Sbjct: 64  CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122

Query: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
            L   +G+  +V VSW  +  VQ F++  +P  + ++E G+AL+LG+ +    L+GG LL
Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181

Query: 184 NCAACSSHAP 193
            C +C   AP
Sbjct: 182 -CLSCQDEAP 190


>gi|6912314 claudin 14 [Homo sapiens]
          Length = 239

 Score =  114 bits (284), Expect = 9e-26
 Identities = 67/190 (35%), Positives = 105/190 (55%), Gaps = 6/190 (3%)

Query: 7   TAMQSVGLLLSLLGWILSIITTYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63
           TA+Q +G LLS LG + ++ITT LPHW+   ++  ++    ++  GLW  CV       Q
Sbjct: 4   TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63

Query: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
           C+ + S LALP +L+ +R LM +S  L  +    +  G+ C R  +     K    ILGG
Sbjct: 64  CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122

Query: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
            L   +G+  +V VSW  +  VQ F++  +P  + ++E G+AL+LG+ +    L+GG LL
Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181

Query: 184 NCAACSSHAP 193
            C +C   AP
Sbjct: 182 -CLSCQDEAP 190


>gi|225703140 claudin 14 [Homo sapiens]
          Length = 239

 Score =  114 bits (284), Expect = 9e-26
 Identities = 67/190 (35%), Positives = 105/190 (55%), Gaps = 6/190 (3%)

Query: 7   TAMQSVGLLLSLLGWILSIITTYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63
           TA+Q +G LLS LG + ++ITT LPHW+   ++  ++    ++  GLW  CV       Q
Sbjct: 4   TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63

Query: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
           C+ + S LALP +L+ +R LM +S  L  +    +  G+ C R  +     K    ILGG
Sbjct: 64  CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122

Query: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
            L   +G+  +V VSW  +  VQ F++  +P  + ++E G+AL+LG+ +    L+GG LL
Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181

Query: 184 NCAACSSHAP 193
            C +C   AP
Sbjct: 182 -CLSCQDEAP 190


>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
          Length = 261

 Score =  112 bits (281), Expect = 2e-25
 Identities = 73/209 (34%), Positives = 106/209 (50%), Gaps = 15/209 (7%)

Query: 7   TAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEME---NWTMGLWQTCVIQEEVGMQ 63
           TA Q +G ++SL+G    I  T +  W   +L  N +    N+  GLW++CV +     +
Sbjct: 4   TACQGLGFVVSLIGIAGIIAATCMDQWSTQDLYNNPVTAVFNY-QGLWRSCVRESSGFTE 62

Query: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
           C+ + + L LPA L+  R LM +   LG +GLLVS F L C+RIG  +   K  + +  G
Sbjct: 63  CRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSG 122

Query: 124 ILSWASGITALVPVSWVAHKTVQEFWDEN----------VPDFVPRWEFGEALFLGWFAG 173
           I+   SG+ A+  VS  A+  V  FW             V     R+ FG ALF+GW AG
Sbjct: 123 IMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAG 182

Query: 174 LSLLLGGCLLNCAACSSHAPLALGHYAVA 202
              L+GG ++ C AC   AP    + AV+
Sbjct: 183 GLTLIGGVMM-CIACRGLAPEETNYKAVS 210


>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
          Length = 261

 Score =  112 bits (280), Expect = 2e-25
 Identities = 74/208 (35%), Positives = 103/208 (49%), Gaps = 13/208 (6%)

Query: 7   TAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64
           T  Q V  LLS+LG    I  T +  W   +L  N + +     GLW++CV Q     +C
Sbjct: 4   TTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGFTEC 63

Query: 65  KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
           + + + L LPA L+  R LM +   LG +GLLVS F L C+RIG  +   K  + +  GI
Sbjct: 64  RPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGI 123

Query: 125 LSWASGITALVPVSWVAHKTVQEFWDEN----------VPDFVPRWEFGEALFLGWFAGL 174
           +   SG+ A+  VS  A+  V  FW             V     R+ FG ALF+GW AG 
Sbjct: 124 MFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGG 183

Query: 175 SLLLGGCLLNCAACSSHAPLALGHYAVA 202
             L+GG ++ C AC   AP    + AV+
Sbjct: 184 LTLIGGVMM-CIACRGLAPEETNYKAVS 210


>gi|6912316 claudin 17 [Homo sapiens]
          Length = 224

 Score =  107 bits (268), Expect = 6e-24
 Identities = 64/183 (34%), Positives = 97/183 (53%), Gaps = 5/183 (2%)

Query: 9   MQSVGLLLSLLGWILSIITTYLPHWKN---LNLDLNEMENWTMGLWQTCVIQEEVGMQCK 65
           +Q  GL+L  LG + ++ TT LP W+    +  ++   E    GLW  C+ Q  V +QCK
Sbjct: 6   LQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARVRLQCK 65

Query: 66  DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
            + S LALP  L  +R LM ++  L  + LL+   G+  ++   S    K  LL   G+L
Sbjct: 66  FYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLGTSGVL 125

Query: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
              +GI  L+PVSW A+  +++F++  +     + E G ALFLGW +   L +GG LL C
Sbjct: 126 FILTGIFVLIPVSWTANIIIRDFYNPAI-HIGQKRELGAALFLGWASAAVLFIGGGLL-C 183

Query: 186 AAC 188
             C
Sbjct: 184 GFC 186


>gi|9966781 claudin 2 [Homo sapiens]
          Length = 230

 Score =  102 bits (253), Expect = 3e-22
 Identities = 56/185 (30%), Positives = 98/185 (52%), Gaps = 6/185 (3%)

Query: 9   MQSVGLLLSLLGWILSIITTYLPHWKN---LNLDLNEMENWTMGLWQTCVIQEEVGMQCK 65
           +Q VG +L LLG + +++   LP WK    +   +     ++ GLW  C        QC 
Sbjct: 6   LQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGITQCD 65

Query: 66  DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
            + + L LPA+++ ++ +M  S+ +  L  ++S  G+ C    +  R  K R+ + GG+ 
Sbjct: 66  IYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESR-AKDRVAVAGGVF 124

Query: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
               G+   +PV+W  H  +++F+   VPD + ++E GEAL+LG  + L  L+ G +L C
Sbjct: 125 FILGGLLGFIPVAWNLHGILRDFYSPLVPDSM-KFEIGEALYLGIISSLFSLIAGIIL-C 182

Query: 186 AACSS 190
            +CSS
Sbjct: 183 FSCSS 187


>gi|5921465 claudin 10 isoform b [Homo sapiens]
          Length = 228

 Score =  100 bits (249), Expect = 1e-21
 Identities = 64/188 (34%), Positives = 99/188 (52%), Gaps = 8/188 (4%)

Query: 7   TAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64
           TA + +  ++S+ GW+L   T    +WK   +D   +   T    LW+ CV        C
Sbjct: 4   TASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNC 63

Query: 65  KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
           KDF S LAL   ++  R LM  +  LGF G + + FG+ C ++G S +  K ++  L GI
Sbjct: 64  KDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDK-AKAKIACLAGI 122

Query: 125 LSWASGITALVPVSWVAHKTVQEFWDENVPDFV-PRWEFGEALFLGWFAGLSLLLGGCLL 183
           +   SG+ ++   S  A+K   EF+D   P FV  ++E G ALF+GW AG SL + G ++
Sbjct: 123 VFILSGLCSMTGCSLYANKITTEFFD---PLFVEQKYELGAALFIGW-AGASLCIIGGVI 178

Query: 184 NCAACSSH 191
            C + S +
Sbjct: 179 FCFSISDN 186


>gi|7656981 claudin 15 [Homo sapiens]
          Length = 228

 Score = 96.7 bits (239), Expect = 1e-20
 Identities = 60/186 (32%), Positives = 93/186 (50%), Gaps = 5/186 (2%)

Query: 8   AMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQCK 65
           A+++ G  ++ +G ++  +T    +W+   +  N +   T+   LW +C         C 
Sbjct: 4   AVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYNCW 63

Query: 66  DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
           +F S LAL   ++  R LM  +  LGFLGLL+   GL C  IG  +   K +L    G L
Sbjct: 64  EFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGAL 123

Query: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG-CLLN 184
              +GI  +V +SW A    ++F+D   P    ++E G AL+LGW A L  +LGG CL +
Sbjct: 124 HILAGICGMVAISWYAFNITRDFFDPLYPG--TKYELGPALYLGWSASLISILGGLCLCS 181

Query: 185 CAACSS 190
              C S
Sbjct: 182 ACCCGS 187


>gi|47716519 claudin 20 [Homo sapiens]
          Length = 219

 Score = 82.8 bits (203), Expect = 2e-16
 Identities = 54/190 (28%), Positives = 93/190 (48%), Gaps = 6/190 (3%)

Query: 9   MQSVGLLLSLLGWILSIITTYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQCK 65
           +Q +  +L+L G    +  T LP+WK N+++D N +       GLW  C         C 
Sbjct: 6   LQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTGMFSCA 65

Query: 66  DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
              S L+LP  ++ +R  M L+  L  LG+  S  G+ C R+G   R+ K      GG+ 
Sbjct: 66  LKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLG-GDRETKSHASFAGGVC 124

Query: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
             ++GI++L+   W   + +  F D  VP+   + E G A+++G+ + + L + G ++ C
Sbjct: 125 FMSAGISSLISTVWYTKEIIANFLDLTVPE-SNKHEPGGAIYIGFISAMLLFISG-MIFC 182

Query: 186 AACSSHAPLA 195
            +C    P A
Sbjct: 183 TSCIKRNPEA 192


>gi|10938016 claudin 11 [Homo sapiens]
          Length = 207

 Score = 74.7 bits (182), Expect = 6e-14
 Identities = 56/194 (28%), Positives = 83/194 (42%), Gaps = 21/194 (10%)

Query: 7   TAMQSVGLLLSLLGWILSIITTYLPHWK-----NLNLDLNEMENWTMGLWQTCVIQEEVG 61
           T +Q VG + S +GWI  I+TT    W       +       E  + GLW  CV+   + 
Sbjct: 4   TCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVMATGL- 62

Query: 62  MQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLIL 121
             CK     L LP  ++  R LM  ++ LG   +L+    L C+R+G+     K R   L
Sbjct: 63  YHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRAQL 122

Query: 122 GGILSWASGITALVPVSW---VAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLL 178
            G+L     + ALV   W    AH+                  FG +L+ GW   +  L+
Sbjct: 123 AGVLLILLALCALVATIWFPVCAHRETTIV------------SFGYSLYAGWIGAVLCLV 170

Query: 179 GGCLLNCAACSSHA 192
           GGC++ C A  + A
Sbjct: 171 GGCVILCCAGDAQA 184


>gi|33598916 claudin 10 isoform a [Homo sapiens]
          Length = 226

 Score = 72.4 bits (176), Expect = 3e-13
 Identities = 46/144 (31%), Positives = 74/144 (51%), Gaps = 6/144 (4%)

Query: 49  GLWQTCVIQEEVGMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIG 108
           GLW  C         C+   +   +   ++  R LM  +  LGF G + + FG+ C ++G
Sbjct: 46  GLWMNCAGNALGSFHCRPHFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVG 105

Query: 109 ESQRDLKRRLLILGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFV-PRWEFGEALF 167
            S +  K ++  L GI+   SG+ ++   S  A+K   EF+D   P FV  ++E G ALF
Sbjct: 106 GSDK-AKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFD---PLFVEQKYELGAALF 161

Query: 168 LGWFAGLSLLLGGCLLNCAACSSH 191
           +GW AG SL + G ++ C + S +
Sbjct: 162 IGW-AGASLCIIGGVIFCFSISDN 184


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.141    0.463 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,387,452
Number of Sequences: 37866
Number of extensions: 348369
Number of successful extensions: 1137
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 1033
Number of HSP's gapped (non-prelim): 58
length of query: 220
length of database: 18,247,518
effective HSP length: 98
effective length of query: 122
effective length of database: 14,536,650
effective search space: 1773471300
effective search space used: 1773471300
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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