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Search of human proteins with 169161522
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169161522 PREDICTED: similar to cell division cycle 2-like 1
(PITSLRE proteins) [Homo sapiens]
(155 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169161522 PREDICTED: similar to cell division cycle 2-like 1 ... 315 1e-86
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 305 8e-84
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 304 2e-83
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 304 2e-83
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 298 1e-81
gi|239747195 PREDICTED: similar to PITSLRE protein kinase beta S... 295 8e-81
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 291 2e-79
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 235 1e-62
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 234 3e-62
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 73 9e-14
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 70 7e-13
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 69 2e-12
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 67 6e-12
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 66 1e-11
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 63 9e-11
gi|148746195 trichohyalin [Homo sapiens] 62 3e-10
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 60 8e-10
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 60 1e-09
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 59 1e-09
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 57 6e-09
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 57 6e-09
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 57 6e-09
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 56 1e-08
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 56 1e-08
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 56 1e-08
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 56 1e-08
gi|62244004 modulator of estrogen induced transcription isoform ... 56 1e-08
gi|63176611 modulator of estrogen induced transcription isoform ... 56 1e-08
gi|56549694 enabled homolog isoform a [Homo sapiens] 55 2e-08
gi|39930375 enabled homolog isoform b [Homo sapiens] 55 2e-08
>gi|169161522 PREDICTED: similar to cell division cycle 2-like 1
(PITSLRE proteins) [Homo sapiens]
Length = 155
Score = 315 bits (807), Expect = 1e-86
Identities = 155/155 (100%), Positives = 155/155 (100%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE 120
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE 120
Query: 121 HERRKRHREEQDKARREWERQKRREMAREHSRRER 155
HERRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 121 HERRKRHREEQDKARREWERQKRREMAREHSRRER 155
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 305 bits (782), Expect = 8e-84
Identities = 154/165 (93%), Positives = 154/165 (93%), Gaps = 10/165 (6%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKR----------K 110
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEK HHRKDEKRKEKR K
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGK 120
Query: 111 HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 155
HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 121 HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 165
Score = 35.4 bits (80), Expect = 0.020
Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 18/168 (10%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRD------SKRDSLEEGELRDH- 56
E+ + + + E +E++ +KE+E +AE +R + R+ + R+ + H
Sbjct: 172 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 231
Query: 57 ----------RMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRK 106
R E+ P + E+ ME+R D I ++ + ++ +
Sbjct: 232 SRSPPRPPRERFELGDGRKPVK-EEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS 290
Query: 107 EKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
E+ + +E+E + EE+++ E E E A E S E
Sbjct: 291 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 338
Score = 35.0 bits (79), Expect = 0.026
Identities = 28/156 (17%), Positives = 62/156 (39%), Gaps = 18/156 (11%)
Query: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
L++ +R++E+E K ++ + + ++ +R + E + R+ R E++ + R + S + +
Sbjct: 168 LEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVK 227
Query: 77 GEEDDSLAIKPPQQM---------SRKEKAHHR---------KDEKRKEKRKHARVKEKE 118
+PP++ ++EK R D +RK + E
Sbjct: 228 ASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESG 287
Query: 119 REHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
E + EE+++ E + E E E
Sbjct: 288 SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 323
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 304 bits (778), Expect = 2e-83
Identities = 152/155 (98%), Positives = 152/155 (98%), Gaps = 1/155 (0%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDH MEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE 120
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEK HHRKDEKRKEK KHARVKEKERE
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK-KHARVKEKERE 119
Query: 121 HERRKRHREEQDKARREWERQKRREMAREHSRRER 155
HERRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 120 HERRKRHREEQDKARREWERQKRREMAREHSRRER 154
Score = 35.4 bits (80), Expect = 0.020
Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 18/168 (10%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRD------SKRDSLEEGELRDH- 56
E+ + + + E +E++ +KE+E +AE +R + R+ + R+ + H
Sbjct: 161 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 220
Query: 57 ----------RMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRK 106
R E+ P + E+ ME+R D I ++ + ++ +
Sbjct: 221 SRSPPRPPRERFELGDGRKPVK-EEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS 279
Query: 107 EKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
E+ + +E+E + EE+++ E E E A E S E
Sbjct: 280 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 327
Score = 35.0 bits (79), Expect = 0.026
Identities = 28/156 (17%), Positives = 62/156 (39%), Gaps = 18/156 (11%)
Query: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
L++ +R++E+E K ++ + + ++ +R + E + R+ R E++ + R + S + +
Sbjct: 157 LEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVK 216
Query: 77 GEEDDSLAIKPPQQM---------SRKEKAHHR---------KDEKRKEKRKHARVKEKE 118
+PP++ ++EK R D +RK + E
Sbjct: 217 ASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESG 276
Query: 119 REHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
E + EE+++ E + E E E
Sbjct: 277 SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 312
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 304 bits (778), Expect = 2e-83
Identities = 152/155 (98%), Positives = 152/155 (98%), Gaps = 1/155 (0%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDH MEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE 120
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEK HHRKDEKRKEK KHARVKEKERE
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK-KHARVKEKERE 119
Query: 121 HERRKRHREEQDKARREWERQKRREMAREHSRRER 155
HERRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 120 HERRKRHREEQDKARREWERQKRREMAREHSRRER 154
Score = 52.4 bits (124), Expect = 2e-07
Identities = 39/139 (28%), Positives = 68/139 (48%), Gaps = 10/139 (7%)
Query: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIK---RLKNSDDRDSKRDSLEEGELRDHRM 58
G+E DS +K ++ +++K ++EK + K R+K + +R E + + R
Sbjct: 77 GEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARRE 136
Query: 59 EITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKE 118
+ RE S +RG + L +Q+ RK + + E++KE+R+ KE+E
Sbjct: 137 WERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQ---KERE 193
Query: 119 REHERRKRHREEQDKARRE 137
R E R++ RE ARRE
Sbjct: 194 RRAEERRKERE----ARRE 208
Score = 35.4 bits (80), Expect = 0.020
Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 18/168 (10%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRD------SKRDSLEEGELRDH- 56
E+ + + + E +E++ +KE+E +AE +R + R+ + R+ + H
Sbjct: 170 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 229
Query: 57 ----------RMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRK 106
R E+ P + E+ ME+R D I ++ + ++ +
Sbjct: 230 SRSPPRPPRERFELGDGRKPVK-EEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS 288
Query: 107 EKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
E+ + +E+E + EE+++ E E E A E S E
Sbjct: 289 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 336
Score = 35.0 bits (79), Expect = 0.026
Identities = 28/156 (17%), Positives = 62/156 (39%), Gaps = 18/156 (11%)
Query: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
L++ +R++E+E K ++ + + ++ +R + E + R+ R E++ + R + S + +
Sbjct: 166 LEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVK 225
Query: 77 GEEDDSLAIKPPQQM---------SRKEKAHHR---------KDEKRKEKRKHARVKEKE 118
+PP++ ++EK R D +RK + E
Sbjct: 226 ASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESG 285
Query: 119 REHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
E + EE+++ E + E E E
Sbjct: 286 SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 321
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 298 bits (764), Expect = 1e-81
Identities = 150/155 (96%), Positives = 150/155 (96%), Gaps = 2/155 (1%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDH MEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE 120
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEK HHRKDEKRKEK KHARV KERE
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARV--KERE 118
Query: 121 HERRKRHREEQDKARREWERQKRREMAREHSRRER 155
HERRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 119 HERRKRHREEQDKARREWERQKRREMAREHSRRER 153
Score = 35.4 bits (80), Expect = 0.020
Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 18/168 (10%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRD------SKRDSLEEGELRDH- 56
E+ + + + E +E++ +KE+E +AE +R + R+ + R+ + H
Sbjct: 160 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 219
Query: 57 ----------RMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRK 106
R E+ P + E+ ME+R D I ++ + ++ +
Sbjct: 220 SRSPPRPPRERFELGDGRKPVK-EEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS 278
Query: 107 EKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
E+ + +E+E + EE+++ E E E A E S E
Sbjct: 279 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 326
Score = 35.0 bits (79), Expect = 0.026
Identities = 28/156 (17%), Positives = 62/156 (39%), Gaps = 18/156 (11%)
Query: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
L++ +R++E+E K ++ + + ++ +R + E + R+ R E++ + R + S + +
Sbjct: 156 LEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVK 215
Query: 77 GEEDDSLAIKPPQQM---------SRKEKAHHR---------KDEKRKEKRKHARVKEKE 118
+PP++ ++EK R D +RK + E
Sbjct: 216 ASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESG 275
Query: 119 REHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
E + EE+++ E + E E E
Sbjct: 276 SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 311
>gi|239747195 PREDICTED: similar to PITSLRE protein kinase beta SV2
[Homo sapiens]
Length = 153
Score = 295 bits (756), Expect = 8e-81
Identities = 149/155 (96%), Positives = 149/155 (96%), Gaps = 2/155 (1%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDH MEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE 120
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMS KEK HHRKDEKRKEK KHARV KERE
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSWKEKVHHRKDEKRKEKWKHARV--KERE 118
Query: 121 HERRKRHREEQDKARREWERQKRREMAREHSRRER 155
HERRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 119 HERRKRHREEQDKARREWERQKRREMAREHSRRER 153
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 291 bits (744), Expect = 2e-79
Identities = 150/165 (90%), Positives = 150/165 (90%), Gaps = 12/165 (7%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDH MEI
Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI 60
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEK----------RK 110
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEK HHRKDEKRKEK K
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGK 120
Query: 111 HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 155
HARV KEREHERRKRHREEQDKARREWERQKRREMAREHSRRER
Sbjct: 121 HARV--KEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 163
Score = 35.4 bits (80), Expect = 0.020
Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 18/168 (10%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRD------SKRDSLEEGELRDH- 56
E+ + + + E +E++ +KE+E +AE +R + R+ + R+ + H
Sbjct: 170 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 229
Query: 57 ----------RMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRK 106
R E+ P + E+ ME+R D I ++ + ++ +
Sbjct: 230 SRSPPRPPRERFELGDGRKPVK-EEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS 288
Query: 107 EKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
E+ + +E+E + EE+++ E E E A E S E
Sbjct: 289 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 336
Score = 35.0 bits (79), Expect = 0.026
Identities = 28/156 (17%), Positives = 62/156 (39%), Gaps = 18/156 (11%)
Query: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
L++ +R++E+E K ++ + + ++ +R + E + R+ R E++ + R + S + +
Sbjct: 166 LEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVK 225
Query: 77 GEEDDSLAIKPPQQM---------SRKEKAHHR---------KDEKRKEKRKHARVKEKE 118
+PP++ ++EK R D +RK + E
Sbjct: 226 ASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESG 285
Query: 119 REHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
E + EE+++ E + E E E
Sbjct: 286 SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 321
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 235 bits (600), Expect = 1e-62
Identities = 116/121 (95%), Positives = 117/121 (96%), Gaps = 1/121 (0%)
Query: 35 LKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK 94
+ SDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK
Sbjct: 1 MSQSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK 60
Query: 95 EKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
EK HHRKDEKRKEK KHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE
Sbjct: 61 EKVHHRKDEKRKEK-KHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 119
Query: 155 R 155
R
Sbjct: 120 R 120
Score = 49.3 bits (116), Expect = 1e-06
Identities = 42/154 (27%), Positives = 77/154 (50%), Gaps = 25/154 (16%)
Query: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEIT 61
G+E DS +K ++ +++K ++EK + K K++ ++ +R E + HR E
Sbjct: 43 GEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK--KHARVKEKER---EHERRKRHREE-- 95
Query: 62 IRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREH 121
RRE + R ++M+R+ H R++ R E+ + R +E+ +
Sbjct: 96 --QDKARREWERQKR------------REMARE---HSRRERDRLEQLERKRERER-KMR 137
Query: 122 ERRKRHREEQDKARREWERQKRREMAREHSRRER 155
E++K RE++++ RR ER+K RE RE S R
Sbjct: 138 EQQKEQREQKERERRAEERRKEREARREVSAHHR 171
Score = 35.4 bits (80), Expect = 0.020
Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 18/168 (10%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRD------SKRDSLEEGELRDH- 56
E+ + + + E +E++ +KE+E +AE +R + R+ + R+ + H
Sbjct: 127 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 186
Query: 57 ----------RMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRK 106
R E+ P + E+ ME+R D I ++ + ++ +
Sbjct: 187 SRSPPRPPRERFELGDGRKPVK-EEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS 245
Query: 107 EKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
E+ + +E+E + EE+++ E E E A E S E
Sbjct: 246 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 293
Score = 35.0 bits (79), Expect = 0.026
Identities = 28/156 (17%), Positives = 62/156 (39%), Gaps = 18/156 (11%)
Query: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
L++ +R++E+E K ++ + + ++ +R + E + R+ R E++ + R + S + +
Sbjct: 123 LEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVK 182
Query: 77 GEEDDSLAIKPPQQM---------SRKEKAHHR---------KDEKRKEKRKHARVKEKE 118
+PP++ ++EK R D +RK + E
Sbjct: 183 ASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESG 242
Query: 119 REHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
E + EE+++ E + E E E
Sbjct: 243 SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 278
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 234 bits (596), Expect = 3e-62
Identities = 117/131 (89%), Positives = 118/131 (90%), Gaps = 10/131 (7%)
Query: 35 LKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK 94
+ SDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK
Sbjct: 1 MSQSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRK 60
Query: 95 EKAHHRKDEKRKEKR----------KHARVKEKEREHERRKRHREEQDKARREWERQKRR 144
EK HHRKDEKRKEKR KHARVKEKEREHERRKRHREEQDKARREWERQKRR
Sbjct: 61 EKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRR 120
Query: 145 EMAREHSRRER 155
EMAREHSRRER
Sbjct: 121 EMAREHSRRER 131
Score = 35.4 bits (80), Expect = 0.020
Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 18/168 (10%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRD------SKRDSLEEGELRDH- 56
E+ + + + E +E++ +KE+E +AE +R + R+ + R+ + H
Sbjct: 138 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 197
Query: 57 ----------RMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRK 106
R E+ P + E+ ME+R D I ++ + ++ +
Sbjct: 198 SRSPPRPPRERFELGDGRKPVK-EEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS 256
Query: 107 EKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
E+ + +E+E + EE+++ E E E A E S E
Sbjct: 257 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 304
Score = 35.0 bits (79), Expect = 0.026
Identities = 28/156 (17%), Positives = 62/156 (39%), Gaps = 18/156 (11%)
Query: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
L++ +R++E+E K ++ + + ++ +R + E + R+ R E++ + R + S + +
Sbjct: 134 LEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVK 193
Query: 77 GEEDDSLAIKPPQQM---------SRKEKAHHR---------KDEKRKEKRKHARVKEKE 118
+PP++ ++EK R D +RK + E
Sbjct: 194 ASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESG 253
Query: 119 REHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
E + EE+++ E + E E E
Sbjct: 254 SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 289
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 73.2 bits (178), Expect = 9e-14
Identities = 44/138 (31%), Positives = 77/138 (55%), Gaps = 4/138 (2%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+EK+R++E+ +K + KR K ++ +R E + R R E R ++E +R
Sbjct: 50 REKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKR--KKEKKKRERK 107
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARRE 137
+ K ++ R+ + R++ KRK++RK R KE++RE ER KR R+ K R++
Sbjct: 108 QRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKR--KKRKK 165
Query: 138 WERQKRREMAREHSRRER 155
ER+K+RE R+ ++ER
Sbjct: 166 EEREKKRERNRKERKKER 183
Score = 69.7 bits (169), Expect = 9e-13
Identities = 40/135 (29%), Positives = 72/135 (53%), Gaps = 8/135 (5%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+ +K+RKE+ EK KR K R+ K+ E + + R E R + RRE + R
Sbjct: 81 EREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE-RERENKQRRERKRKKRR 139
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARRE 137
+ K ++ ++EK +++ KRK+++K R K++ER + RK+ RE +++ R+
Sbjct: 140 K-------KKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERK 192
Query: 138 WERQKRREMAREHSR 152
ER+K R +E +
Sbjct: 193 KERKKERRKKKERKK 207
Score = 68.9 bits (167), Expect = 2e-12
Identities = 43/142 (30%), Positives = 74/142 (52%), Gaps = 10/142 (7%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+++KR +E+E K E KR E G+ R+ + + + RRE R
Sbjct: 44 EKRKREREKERKRE-----RGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRK 98
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARRE 137
+E K + RK+K RK+ +R+ K++ R ++K R+ +RRK + E+++ +RE
Sbjct: 99 KEKKKRERKQRGRRERKKK-KERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRE 157
Query: 138 WERQKR----REMAREHSRRER 155
+R+KR RE RE +R+ER
Sbjct: 158 RKRKKRKKEEREKKRERNRKER 179
Score = 62.4 bits (150), Expect = 2e-10
Identities = 41/138 (29%), Positives = 77/138 (55%), Gaps = 7/138 (5%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+EKK+RK++E E +R + +R+ +R E E R + E R R++ +R
Sbjct: 61 KEKKKRKKRERGKERERKRK--EREKQRKERREKERRKRKKEKKKRE---RKQRGRRERK 115
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARRE 137
++ + + + R+ K R+ +KR+++RK + + K RE +R+KR +EE++K +RE
Sbjct: 116 KKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGK-RERKRKKRKKEEREK-KRE 173
Query: 138 WERQKRREMAREHSRRER 155
R++R++ RRER
Sbjct: 174 RNRKERKKERERKERRER 191
Score = 58.9 bits (141), Expect = 2e-09
Identities = 34/136 (25%), Positives = 71/136 (52%), Gaps = 19/136 (13%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+E +R+KE+ E+ + KR + +++ KR+ R +++ +RG
Sbjct: 32 RESERKKERREREKRKRER---EKERKRE----------------RGKKEKKKRKKRERG 72
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARRE 137
+E + + +Q + + RK +K K+KR+ + +ER+ ++ ++ RE ++K RRE
Sbjct: 73 KERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRE 132
Query: 138 WERQKRREMAREHSRR 153
+R+KRR+ R R+
Sbjct: 133 RKRKKRRKKKRRKERK 148
Score = 55.8 bits (133), Expect = 1e-08
Identities = 23/67 (34%), Positives = 47/67 (70%)
Query: 89 QQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAR 148
++ ++E+ RK E+ K+++K + +E+ +E ER+++ RE+Q K RRE ER+KR++ +
Sbjct: 43 REKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKK 102
Query: 149 EHSRRER 155
+ R++R
Sbjct: 103 KRERKQR 109
Score = 42.7 bits (99), Expect = 1e-04
Identities = 26/94 (27%), Positives = 49/94 (52%), Gaps = 7/94 (7%)
Query: 68 RREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRH 127
+RE + E + + ++ R+ +K K++E+ K K KERE ++RK
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKERE-KQRKER 89
Query: 128 REEQ------DKARREWERQKRREMAREHSRRER 155
RE++ +K +RE +++ RRE ++ R+ER
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKER 123
Score = 42.4 bits (98), Expect = 2e-04
Identities = 28/107 (26%), Positives = 57/107 (53%), Gaps = 8/107 (7%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+E+K++KE++E+ +N R+ KR + + R R R +RE + R
Sbjct: 112 RERKKKKERKERER----ENKQRRERKRKKRRKKKRRKERKREKERG---KRERKRKKRK 164
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERR 124
+E+ + ++ +KE+ + E++KE++K R K+KER+ +R+
Sbjct: 165 KEEREKKRERNRKERKKERERKERRERKKERKKERR-KKKERKKDRK 210
Score = 33.5 bits (75), Expect = 0.075
Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 6/70 (8%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+ KKR+KE+ EK KR +N +R +R+ E E + R + R R++D DR
Sbjct: 159 KRKKRKKEEREK---KRERNRKERKKERERKERRERKKERKK-ERRKKKERKKDRKTDR- 213
Query: 78 EEDDSLAIKP 87
+ DS +P
Sbjct: 214 -QTDSQVFRP 222
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 70.1 bits (170), Expect = 7e-13
Identities = 50/146 (34%), Positives = 80/146 (54%), Gaps = 9/146 (6%)
Query: 18 QEKKRRKEQEEK-AEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
+ KKRR+E+E K E K + ++ + + +EG+ R+ R E R RE E+R
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERE-RKEERKREERKERERKKEER 154
Query: 77 GEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHAR---VKEKEREH-ERRKRHREEQD 132
+E + K ++ EK RK+++RKE++K R ++KERE ERR+R +E +
Sbjct: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
Query: 133 KARREWERQKRRE---MAREHSRRER 155
K R+ ERQK R+ +E +RER
Sbjct: 215 KEERKKERQKDRQTNWREKERGKRER 240
Score = 66.6 bits (161), Expect = 8e-12
Identities = 45/149 (30%), Positives = 80/149 (53%), Gaps = 18/149 (12%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+E +R+KE+ E+ + KR + + + + ++GE + R RR + G
Sbjct: 55 RESERKKERREREKRKREREKERKRERGKKEKKGERKKEE-----RERKKRRREKENKEG 109
Query: 78 EEDDSLAIKPPQQMSR-------KEKAHHRKDEKRKEKRKHARVKEKEREH-ERRKRHRE 129
EE + K ++ R +E+ RK E+RKE+ + +EKERE ER+KR R+
Sbjct: 110 EEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERK 169
Query: 130 ---EQDKARREWERQKRREMAREHSRRER 155
E+++ R+E ER++R++ RE +R+ER
Sbjct: 170 QVGEKEEERKEKERKERKK--RERNRKER 196
Score = 62.4 bits (150), Expect = 2e-10
Identities = 45/150 (30%), Positives = 76/150 (50%), Gaps = 16/150 (10%)
Query: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEIT 61
G+EK+ K K E + K KE+E K E KR ++R + EE E R E
Sbjct: 109 GEEKEKRKKKEKKERGRTSKEGKERERKEERKR----EERKERERKKEEREKERERKE-- 162
Query: 62 IRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE- 120
R++ + GE+++ K ++ RK++ +RK+ K++ +RK R ++KER+
Sbjct: 163 ------RKKRERKQVGEKEEER--KEKERKERKKRERNRKERKKERERKERRERKKERKK 214
Query: 121 -HERRKRHREEQDKARREWERQKRREMARE 149
ER+K ++++ RE ER KR R+
Sbjct: 215 KEERKKERQKDRQTNWREKERGKRERKERK 244
Score = 62.0 bits (149), Expect = 2e-10
Identities = 34/137 (24%), Positives = 74/137 (54%), Gaps = 5/137 (3%)
Query: 20 KKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEE 79
KK +K + +K E +R K ++++K +E + + E + + + E+R E
Sbjct: 83 KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKRE 142
Query: 80 DDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARR--E 137
+ + ++ +EK RK+ K++E+++ +E+ +E ER++R + E+++ R E
Sbjct: 143 ERK---ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKE 199
Query: 138 WERQKRREMAREHSRRE 154
ER++RRE +E ++E
Sbjct: 200 RERKERRERKKERKKKE 216
Score = 55.5 bits (132), Expect = 2e-08
Identities = 33/136 (24%), Positives = 72/136 (52%), Gaps = 5/136 (3%)
Query: 20 KKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEE 79
++R +E E + E K+ + S+ + +R E E R E + ++E E + EE
Sbjct: 39 REREREIETRKEGKKERESERKKERR----EREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 80 DDSLAIKPPQQMSRKEKAHHRKDEKRKEK-RKHARVKEKEREHERRKRHREEQDKARREW 138
+ + ++ E+ RK +++KE+ R KE+ER+ ER++ R+E+++ + E
Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
Query: 139 ERQKRREMAREHSRRE 154
E+++ R+ ++ R++
Sbjct: 155 EKERERKERKKRERKQ 170
Score = 49.7 bits (117), Expect = 1e-06
Identities = 28/113 (24%), Positives = 58/113 (51%), Gaps = 7/113 (6%)
Query: 50 EGELRDHRMEITIRNSPYRREDS-----MEDRGEEDDSLAIKPPQQMSRKEKAHHRKDE- 103
+ E+R+ EI R + +S +R + + ++ +KEK RK E
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 104 -KRKEKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 155
+RK++R+ KE E + +R+K+ ++E+ + +E + ++R+E + R+ER
Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER 147
Score = 40.8 bits (94), Expect = 5e-04
Identities = 20/70 (28%), Positives = 36/70 (51%)
Query: 86 KPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARREWERQKRRE 145
+P Q +E+ + K +K + + K++ RE E+RKR RE++ K R + +K
Sbjct: 31 QPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER 90
Query: 146 MAREHSRRER 155
E R++R
Sbjct: 91 KKEERERKKR 100
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 68.9 bits (167), Expect = 2e-12
Identities = 55/176 (31%), Positives = 88/176 (50%), Gaps = 27/176 (15%)
Query: 3 DEKDSWKVKTLDEILQEKK---RRKEQEEKAEIKRLKNSDDRDS-KRDSLEEGELRDHRM 58
D+ S+K+KT+ + EKK R+K EEKA++++LK ++ ++ K+D ++ E +
Sbjct: 218 DDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFE 277
Query: 59 EITIRNS--------PYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRK 110
E T+++ P E + EDD+ K + K+K K+EK KEK+K
Sbjct: 278 EETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKD---KKKKKGEKEEKEKEKKK 334
Query: 111 -----------HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 155
A K KE E ER+KR EE+ K E E +++ E E +RER
Sbjct: 335 GPSKATVKAMQEALAKLKEEE-ERQKREEEERIKRLEELEAKRKEEERLEQEKRER 389
Score = 40.0 bits (92), Expect = 8e-04
Identities = 32/123 (26%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Query: 20 KKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEE 79
KK +E++ K++K +S +S +E + + +N + ++E G E
Sbjct: 159 KKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIES-GNE 217
Query: 80 DDSLAIKPPQQMSRKEKAHHRKDEKR-KEKRKHARVKEKEREHERRKRHREEQDKARREW 138
DD + K +K + R+ +KR +EK K ++KEKE E E K+ + +Q +++R++
Sbjct: 218 DDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKE-ELETGKKDQSKQKESQRKF 276
Query: 139 ERQ 141
E +
Sbjct: 277 EEE 279
Score = 40.0 bits (92), Expect = 8e-04
Identities = 31/119 (26%), Positives = 59/119 (49%), Gaps = 8/119 (6%)
Query: 27 EEKAEIKRLKNSDD------RDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEED 80
EEKAE D+ +D K+ E+ E + + + + ++++ EE+
Sbjct: 296 EEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEE 355
Query: 81 DSLAIKPPQQMSRKEKAH-HRKDEKRKEKRKHARVKEKEREH-ERRKRHREEQDKARRE 137
+ + +++ R E+ RK+E+R E+ K R K+KE+E ER K+ + K++RE
Sbjct: 356 ERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQRE 414
Score = 40.0 bits (92), Expect = 8e-04
Identities = 31/127 (24%), Positives = 61/127 (48%), Gaps = 15/127 (11%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
M ++++ KV+ ++ K+ +E+EE+ E + +D +S+ + EEGE +
Sbjct: 509 MASDEETEKVEGNKVHIEVKENPEEEEEEEE----EEEEDEESEEEEEEEGESEGSEGD- 563
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE 120
++ + D + +L KP ++MS + + D++ KE+R A K K R
Sbjct: 564 -------EEDEKVSDEKDSGKTLDKKPSKEMS-SDSEYDSDDDRTKEER--AYDKAKRRI 613
Query: 121 HERRKRH 127
+RR H
Sbjct: 614 EKRRLEH 620
Score = 39.3 bits (90), Expect = 0.001
Identities = 38/162 (23%), Positives = 70/162 (43%), Gaps = 27/162 (16%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSDDRDS-----------------KRDSLEEGELRDHR 57
E L++K + ++ K +++ SDD D K D EE E D+
Sbjct: 114 EELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDE--DNS 171
Query: 58 MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKA-----HHRKDEKRKEKRKHA 112
+I R+ R S E E D+ L + Q+ ++K K +D+ K K
Sbjct: 172 KKIKERS---RINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTV 228
Query: 113 RVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
K+ E++ RK+ EE+ K R+ E+++ ++ S+++
Sbjct: 229 AQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQK 270
Score = 37.7 bits (86), Expect = 0.004
Identities = 33/154 (21%), Positives = 69/154 (44%), Gaps = 15/154 (9%)
Query: 10 VKTLDEILQEKKR-----RKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRN 64
V+ +++ + EK+ E+EE E L DD ++ E ++ +++ I ++
Sbjct: 473 VEVMEQGVPEKEETPPPVEPEEEEDTEDAGL---DDWEAMASDEETEKVEGNKVHIEVKE 529
Query: 65 SPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERR 124
+P E+ E+ EED+ + ++ + +DEK +++ + +K+ E
Sbjct: 530 NPEEEEEE-EEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMS 588
Query: 125 KRHREEQD----KARREWERQKRREMAR--EHSR 152
+ D K R +++ KRR R EHS+
Sbjct: 589 SDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSK 622
Score = 33.5 bits (75), Expect = 0.075
Identities = 26/128 (20%), Positives = 58/128 (45%), Gaps = 15/128 (11%)
Query: 10 VKTLDEIL---QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSP 66
VK + E L +E++ R+++EE+ IKRL+ + + + + LE+ + + + R
Sbjct: 341 VKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKER 400
Query: 67 YRREDSMEDRGEED------------DSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARV 114
++E + + + + + ++ P + S +K +D+KRK+ +
Sbjct: 401 LKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLES 460
Query: 115 KEKEREHE 122
KE E
Sbjct: 461 KEVSESME 468
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 67.0 bits (162), Expect = 6e-12
Identities = 43/139 (30%), Positives = 68/139 (48%), Gaps = 1/139 (0%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
Q + E++E+ E +R+ DDR +R + E R R RE E
Sbjct: 648 QGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKEREL 707
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARRE 137
E + + + ++ R + +D R+ +R+ R +EKERE ER +R RE + + RE
Sbjct: 708 ERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERE 767
Query: 138 WERQKRREMAREHSR-RER 155
ER++ RE ARE + RER
Sbjct: 768 RERERERERARERDKERER 786
Score = 65.1 bits (157), Expect = 2e-11
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 16/169 (9%)
Query: 3 DEKDSWKVKTLDEILQEKKRR----KEQEEKAEIKRLKNSDD--RDSKRDSLEEGELRDH 56
D +D + + + E+ RR ++Q + I+ +D+ RD +R+ + D
Sbjct: 612 DNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDR 671
Query: 57 RMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEK-------R 109
R E R D +R E + + ++ +E+A R+ E+ KE+ R
Sbjct: 672 RDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDR 731
Query: 110 KHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSR---RER 155
H R +E+ERE +R K E+++ RE ER++ RE RE R RER
Sbjct: 732 DHDRERERERERDREKEREREREERERERERERERERERERERERARER 780
Score = 62.8 bits (151), Expect = 1e-10
Identities = 42/151 (27%), Positives = 72/151 (47%), Gaps = 18/151 (11%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSM 73
DE +E+ R +E++ + E +R + D K LE R+ E R D
Sbjct: 673 DERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRD 732
Query: 74 EDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHER-RKRHREEQD 132
DR E + + +EK R+ E+R+ +R+ R +E+ERE ER R R R+++
Sbjct: 733 HDRERERE--------RERDREKEREREREERERERERERERERERERERERARERDKER 784
Query: 133 KARREWE---------RQKRREMAREHSRRE 154
+ +R+WE R+KR E+ + + R+
Sbjct: 785 ERQRDWEDKDKGRDDRREKREEIREDRNPRD 815
Score = 55.5 bits (132), Expect = 2e-08
Identities = 47/168 (27%), Positives = 79/168 (47%), Gaps = 23/168 (13%)
Query: 6 DSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNS 65
DSW+ ++ E+ R E++ + + R + + R +RD + E RD R IR+
Sbjct: 594 DSWETRSS---YPERDRYPERDNRDQA-RDSSFERRHGERDRRDNRE-RDQRPSSPIRHQ 648
Query: 66 PYRREDSMEDRGEE------DDSLAIKPPQQMSRKEKAHHRKDEKRKEK---RKHARVKE 116
E ++R EE DD + ++ +E+ R+ E+ +E+ R+ R E
Sbjct: 649 GRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELE 708
Query: 117 KEREHERRKRHREEQDKAR---------REWERQKRREMAREHSRRER 155
+ER ER + +E+D+ R RE ER++ RE RE R ER
Sbjct: 709 RERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREER 756
Score = 52.8 bits (125), Expect = 1e-07
Identities = 42/151 (27%), Positives = 70/151 (46%), Gaps = 25/151 (16%)
Query: 5 KDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRN 64
+D K K+L EI E+K R +Q ++ E R +SD +DS R+
Sbjct: 1233 RDREKTKSL-EITGERKSRIDQLKRGEPSRSTSSDRQDS-------------------RS 1272
Query: 65 SPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHER- 123
RR DR S + ++ +++ H D +R+ +R+ R +E +R+ ++
Sbjct: 1273 HSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEH--DRERERERRDTRQREWDRDADKD 1330
Query: 124 --RKRHREEQDKARREWERQKRREMAREHSR 152
R R R+ + RE ER KRR++ RE R
Sbjct: 1331 WPRNRDRDRLRERERERERDKRRDLDRERER 1361
Score = 46.6 bits (109), Expect = 9e-06
Identities = 37/138 (26%), Positives = 59/138 (42%), Gaps = 4/138 (2%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRRE-DSMEDR 76
Q RR E+ E KR + D R+ + ++ RDHR + R+ RR+ DR
Sbjct: 408 QSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDR 467
Query: 77 GEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARR 136
E DS ++ ++M ++ + K+ + + R R+ E R HR+E D
Sbjct: 468 RELRDSRDMRDSREM--RDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKE-DTYPE 524
Query: 137 EWERQKRREMAREHSRRE 154
E R + E SR E
Sbjct: 525 ESRSYGRNHLREESSRTE 542
Score = 45.4 bits (106), Expect = 2e-05
Identities = 40/146 (27%), Positives = 69/146 (47%), Gaps = 15/146 (10%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSD---DRDSKRDSLEEGELRDHRMEITIRNSPYRRED 71
E+ +E+ R +E+E + E R ++ D DR+ +R+ + E ++ E R RE
Sbjct: 706 ELERERAREREREREKERDRERDRDRDHDRERERERERDRE-KEREREREERERERERER 764
Query: 72 SMEDRGEEDDSLAIKPPQQMSR------KEKAHHRKDEKRKEKRKHARVKEKEREHERRK 125
E E + A + ++ R K+K + EKR+E R+ ++ E + +K
Sbjct: 765 ERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKK 824
Query: 126 RHREEQDKARREWERQKRREMAREHS 151
R+R E + R + KRR REHS
Sbjct: 825 RYRNEGSPSPR--QSPKRR---REHS 845
Score = 44.7 bits (104), Expect = 3e-05
Identities = 37/140 (26%), Positives = 59/140 (42%), Gaps = 3/140 (2%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+EK R+E+E + + ++ D RD + + RD R +R+S R DS E R
Sbjct: 426 REKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMR-DSREMRD 484
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKD-EKRKEKRKHARVKEKEREHERRK-RHREEQDKAR 135
D+ + P+ AH +D E R RK E+ R + R R + + R
Sbjct: 485 YSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIR 544
Query: 136 REWERQKRREMAREHSRRER 155
E + R E+ + R R
Sbjct: 545 NESRNESRSEIRNDRMGRSR 564
Score = 44.7 bits (104), Expect = 3e-05
Identities = 40/169 (23%), Positives = 75/169 (44%), Gaps = 29/169 (17%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSD-DRDSKRDSLEEGELRDHRMEITI 62
EK+ + + E +E++R +E+E + E +R + D +R+ +RD ++ + RD R E
Sbjct: 746 EKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRRE--- 802
Query: 63 RNSPYRREDSMEDRGEEDDSLAIK-----------PPQQMSRKEKAH-------HRKDEK 104
+RE+ EDR D K P+Q ++ + H + D+K
Sbjct: 803 -----KREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDK 857
Query: 105 RKEKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRR 153
++ R ++V + H E + R W+ + R+ +E SRR
Sbjct: 858 NEKHRLLSQVVRPQESRSLSPSHLTEDRQGR--WKEEDRKPERKESSRR 904
Score = 43.1 bits (100), Expect = 9e-05
Identities = 37/133 (27%), Positives = 64/133 (48%), Gaps = 6/133 (4%)
Query: 27 EEKAEIKRLKNSDDRD-SKRDSLEEGELRDHRMEITIRNSPYRR--EDSMEDRGEEDDSL 83
++++ KR+ +S RD K SLE R R++ R P R D + R
Sbjct: 1219 DDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRS 1278
Query: 84 AIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARREWERQKR 143
+ + +Q+ + + +D + +E+ ++ +E+ERE R R RE A ++W R +
Sbjct: 1279 SPESDRQVHSRSGSFDSRD-RLQERDRYEHDRERERE-RRDTRQREWDRDADKDWPRNRD 1336
Query: 144 REMAREHSR-RER 155
R+ RE R RER
Sbjct: 1337 RDRLRERERERER 1349
Score = 35.8 bits (81), Expect = 0.015
Identities = 41/175 (23%), Positives = 73/175 (41%), Gaps = 30/175 (17%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNS----DDRDSKRDSLEEGELRDHRME 59
E+D + + D ++K R +E++ EI+ +N D+R SK+ EG
Sbjct: 779 ERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSP---- 834
Query: 60 ITIRNSPYRRED---------SMEDRGEEDDSLAIKPPQQMSRKEKAHHR--------KD 102
R SP RR + S +D+ E+ L+ Q SR H K+
Sbjct: 835 ---RQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKE 891
Query: 103 EKRKEKRKHA--RVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 155
E RK +RK + R +E+E + + ++ + E R + +++ H +R
Sbjct: 892 EDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDR 946
Score = 35.4 bits (80), Expect = 0.020
Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 13/95 (13%)
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKE---KRKHARVKEKER 119
+ SP R M ++G D R ++H R+ E+R++ KR + +ER
Sbjct: 385 KQSPPRHRSPMREKGRHDHE----------RTSQSHDRRHERREDTRGKRDREKDSREER 434
Query: 120 EHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
E+E+ + + R + + RR+ RRE
Sbjct: 435 EYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRE 469
Score = 35.0 bits (79), Expect = 0.026
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 8/80 (10%)
Query: 82 SLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEK-EREHERR-----KRHREEQDKAR 135
S ++ PQ+ ++ HR + K + H R + +R HERR KR RE+ +
Sbjct: 376 SHSLSSPQR--KQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREE 433
Query: 136 REWERQKRREMAREHSRRER 155
RE+E+ + R R
Sbjct: 434 REYEQDQSSSRDHRDDREPR 453
Score = 29.3 bits (64), Expect = 1.4
Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 10/102 (9%)
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMS--------RKEKAHHRKDEKRKEKRKHARV 114
R SP R + +R + PQ+ + RKE + R EK K R
Sbjct: 75 RRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERT 134
Query: 115 KEKEREHERRKRHREEQDKA--RREWERQKRREMAREHSRRE 154
E E E+ + +R++ D ++ + EM R+ +RE
Sbjct: 135 PESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRE 176
Score = 29.3 bits (64), Expect = 1.4
Identities = 26/132 (19%), Positives = 53/132 (40%), Gaps = 3/132 (2%)
Query: 23 RKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDS 82
+++Q ++ D +R S + + R R E T R R +DS E+R E D
Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTS-QSHDRRHERREDT-RGKRDREKDSREEREYEQDQ 440
Query: 83 LAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARREWERQK 142
+ + + R+D + R+ R R+ + + + ++R + +
Sbjct: 441 SSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRS 500
Query: 143 RREMAREHSRRE 154
R+ A ++ RE
Sbjct: 501 TRD-AHDYRDRE 511
Score = 29.3 bits (64), Expect = 1.4
Identities = 16/71 (22%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
Query: 87 PPQQMS--RKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARREWERQKRR 144
PP+ S R++ H + + R+H R ++ + +R K REE++ + + + R
Sbjct: 388 PPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHR 447
Query: 145 EMAREHSRRER 155
+ R+R
Sbjct: 448 DDREPRDGRDR 458
Score = 28.9 bits (63), Expect = 1.9
Identities = 30/150 (20%), Positives = 56/150 (37%), Gaps = 20/150 (13%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITI 62
D +D+ + E+ + R +E + + K S D R + + + RD T
Sbjct: 457 DRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDT- 515
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEK-EREH 121
+R+ED+ P++ + H R++ R E R +R + + E +
Sbjct: 516 ----HRKEDTY--------------PEESRSYGRNHLREESSRTEIRNESRNESRSEIRN 557
Query: 122 ERRKRHREEQDKARREWERQKRREMAREHS 151
+R R R + + R R HS
Sbjct: 558 DRMGRSRGRVPELPEKGSRGSRGSQIDSHS 587
Score = 28.5 bits (62), Expect = 2.4
Identities = 27/137 (19%), Positives = 57/137 (41%), Gaps = 13/137 (9%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
Q KRR+E ++ + DD++ K L + + SP + + R
Sbjct: 836 QSPKRRREHSPDSDA--YNSGDDKNEKHRLLSQVVRPQESRSL----SPSHLTEDRQGRW 889
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARRE 137
+E+D KP RKE + ++++ KEK + ++ E R R + +
Sbjct: 890 KEEDR---KP----ERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQ 942
Query: 138 WERQKRREMAREHSRRE 154
E ++ + A + ++++
Sbjct: 943 SEDRETSDRAHDENKKK 959
Score = 27.3 bits (59), Expect = 5.4
Identities = 22/132 (16%), Positives = 58/132 (43%), Gaps = 12/132 (9%)
Query: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEIT 61
GD+K+ K + L ++++ ++ R L S + ++ +E + + R E +
Sbjct: 854 GDDKNE-KHRLLSQVVRPQESRS----------LSPSHLTEDRQGRWKEEDRKPERKESS 902
Query: 62 IRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEK-AHHRKDEKRKEKRKHARVKEKERE 120
R ++ + ++ + I +M ++ HH+ +++ R H K+K +
Sbjct: 903 RRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKI 962
Query: 121 HERRKRHREEQD 132
++ + ++E D
Sbjct: 963 QKKPIKKKKEDD 974
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 66.2 bits (160), Expect = 1e-11
Identities = 43/148 (29%), Positives = 79/148 (53%), Gaps = 15/148 (10%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+E++R K ++E+ E +R + +++ R S E G R+ E R+ D DR
Sbjct: 177 KEREREKNRQERRERERQREKENKTEDRHS-ERGRERERERETETETERKRQTDRERDRQ 235
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKH--------ARVKEKEREHERRKRHRE 129
+ + + ++ + +E+A R+ E+ KE+ + R KE+ER+ +R+++ R
Sbjct: 236 RKTE----REREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT 291
Query: 130 EQDK-ARREWERQKRREMAREHSR-RER 155
E+D+ R+ ERQ+ RE RE +R RER
Sbjct: 292 ERDRETERKRERQRERERERERNRKRER 319
Score = 66.2 bits (160), Expect = 1e-11
Identities = 43/139 (30%), Positives = 75/139 (53%), Gaps = 5/139 (3%)
Query: 20 KKRRKEQEEKAEIKRLKNSD-DRDSKRDSLEEGELRDHRMEITIRNSPYRREDSME-DRG 77
++R +E+E + E +R + +D +RD +R + E E + R + R + +E E DR
Sbjct: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD 269
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHER-RKRHREEQDKARR 136
+ D + +Q RK + +D R+ +RK R +E+ERE ER RKR RE + + R
Sbjct: 270 RDRDRRQKERERQTDRKRQRRTERD--RETERKRERQRERERERERNRKRERERERERER 327
Query: 137 EWERQKRREMAREHSRRER 155
E +R+ R+ +E R+ +
Sbjct: 328 ERQRETERDREKERERKRK 346
Score = 60.8 bits (146), Expect = 4e-10
Identities = 38/136 (27%), Positives = 73/136 (53%), Gaps = 11/136 (8%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+++K +E+E++AE +R + +R+++RD E E R + R+ D R
Sbjct: 234 RQRKTEREREKQAERER---ASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRR 290
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARRE 137
E D ++ RK + ++ +R+ RK R +E+ERE ER++ +++K RE
Sbjct: 291 TERD-------RETERKRERQRERERERERNRKRERERERERERERQRETERDREK-ERE 342
Query: 138 WERQKRREMAREHSRR 153
+R+++ EM RE +R+
Sbjct: 343 RKRKRQTEMDRERNRQ 358
Score = 59.3 bits (142), Expect = 1e-09
Identities = 41/145 (28%), Positives = 69/145 (47%), Gaps = 10/145 (6%)
Query: 21 KRRKEQEEKAEIKRLKNSD---DRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+R +E++ AE +R + +D R ++R+ +E E +R E R +E+ EDR
Sbjct: 146 QRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRH 205
Query: 78 EE---DDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKE----REHERRKRHREE 130
E + + + RK + +D +RK +R+ + E+E RE ER K E
Sbjct: 206 SERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERE 265
Query: 131 QDKARREWERQKRREMAREHSRRER 155
+D+ R RQK RE + R+ R
Sbjct: 266 RDRDRDRDRRQKERERQTDRKRQRR 290
Score = 57.0 bits (136), Expect = 6e-09
Identities = 42/160 (26%), Positives = 74/160 (46%), Gaps = 13/160 (8%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIR 63
E+D + + Q ++ R + E K + DRD RD ++ R T R
Sbjct: 231 ERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQK-----ERERQTDR 285
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHER 123
R E E + + + ++ +RK + ++ +R+ +R+ R +EKERE +R
Sbjct: 286 KRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKR 345
Query: 124 -------RKRHREEQDKARREWERQKRREMARE-HSRRER 155
R+R+R+ + RR+ ER++ RE R+ S RER
Sbjct: 346 KRQTEMDRERNRQTGREGRRQAERERERERERDRQSARER 385
Score = 56.6 bits (135), Expect = 8e-09
Identities = 42/156 (26%), Positives = 71/156 (45%), Gaps = 11/156 (7%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSD-DRDSKRDSLEEGELRDHRMEITI 62
E+D + + D +R+KE+E + + KR + ++ DR+++R + E R+ E
Sbjct: 257 ERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRE-RERERE--- 312
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKE------KRKHARVKE 116
RN RE E E ++ RK K D +R +R+ R +E
Sbjct: 313 RNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERE 372
Query: 117 KEREHERRKRHREEQDKARREWERQKRREMAREHSR 152
+ERE +R+ E+ + R+ +RQK RE E R
Sbjct: 373 RERERDRQSAREREERERDRDRDRQKERERQTEKDR 408
Score = 55.1 bits (131), Expect = 2e-08
Identities = 40/138 (28%), Positives = 68/138 (49%), Gaps = 17/138 (12%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+EK+R ++++ + E+ R +N R + R+ + E R R S RE+ DR
Sbjct: 337 REKERERKRKRQTEMDRERN---RQTGREGRRQAERERERERERDRQSAREREERERDRD 393
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHER---RKRHREEQDKA 134
+ K ++ + K++ R+ EK++E+ EK+RE ER R R RE+Q
Sbjct: 394 RDRQ----KERERQTEKDRDGQRETEKQRER-------EKDRESERGRERGREREKQKGR 442
Query: 135 RREWERQKRREMAREHSR 152
R+ ERQ R+ R+ R
Sbjct: 443 ERDRERQTDRQAGRQRKR 460
Score = 54.7 bits (130), Expect = 3e-08
Identities = 35/143 (24%), Positives = 71/143 (49%), Gaps = 13/143 (9%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRD-SKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
+E+ R+KE+E + E ++ + DR +R + RD E R+ D ++R
Sbjct: 54 RERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRE--------RQRDREKER 105
Query: 77 GEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARV---KEKEREHERRKRHREEQDK 133
+ D + ++ ++K R+ E+ E+ + + +E+ER+ + K + D+
Sbjct: 106 ERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDR 165
Query: 134 AR-REWERQKRREMAREHSRRER 155
R R+ ER +++E RE +R+ER
Sbjct: 166 ERQRQTERNRQKEREREKNRQER 188
Score = 54.3 bits (129), Expect = 4e-08
Identities = 43/155 (27%), Positives = 76/155 (49%), Gaps = 14/155 (9%)
Query: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEIT 61
GD+++ + K + ++++ +E + K E +R K DR KRD E + RD E
Sbjct: 51 GDDRERNRQKERERRREKRQTERETDRKRERRREK---DRHRKRDRHRERQ-RDREKERE 106
Query: 62 IRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREH 121
R+ D DR E + K ++ + +E R D + +R+ R ++ E+E
Sbjct: 107 ------RQTDRERDRQREKERNRQKERERETEREGERGR-DRQTDGQRERERQRDAEKER 159
Query: 122 ER---RKRHREEQDKARREWERQKRREMAREHSRR 153
ER R+R R+ + ++E ER+K R+ RE R+
Sbjct: 160 ERQTDRERQRQTERNRQKEREREKNRQERRERERQ 194
Score = 54.3 bits (129), Expect = 4e-08
Identities = 46/156 (29%), Positives = 77/156 (49%), Gaps = 12/156 (7%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSD---DRDSKRDSLEEGELRDHRMEI 60
E++ + K E ++KR + +E+ KR ++ + DR+ +R+ + E RD + E
Sbjct: 61 ERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE-RDRQREK 119
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE 120
RN RE E GE + Q ++E+ R EK +E R+ R ++++ E
Sbjct: 120 E-RNRQKERERETEREGERG-----RDRQTDGQRERERQRDAEKERE-RQTDRERQRQTE 172
Query: 121 HERRK-RHREEQDKARREWERQKRREMAREHSRRER 155
R+K R RE+ + RRE ERQ+ +E E ER
Sbjct: 173 RNRQKEREREKNRQERRERERQREKENKTEDRHSER 208
Score = 53.9 bits (128), Expect = 5e-08
Identities = 42/156 (26%), Positives = 67/156 (42%), Gaps = 14/156 (8%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGE-LRDHRMEITI 62
EK+ + + Q +K R Q+E+ + RD + D E E RD E
Sbjct: 102 EKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERER 161
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHE 122
+ R+ + +R +E + + + R+E+ R+ E + E R R +E+ERE E
Sbjct: 162 QTDRERQRQTERNRQKERE----REKNRQERRERERQREKENKTEDRHSERGRERERERE 217
Query: 123 ---------RRKRHREEQDKARREWERQKRREMARE 149
+ R R+ Q K RE E+Q RE A E
Sbjct: 218 TETETERKRQTDRERDRQRKTEREREKQAERERASE 253
Score = 53.5 bits (127), Expect = 7e-08
Identities = 33/138 (23%), Positives = 67/138 (48%), Gaps = 1/138 (0%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+E +R KE+E + + R ++ ++ +R + + + R R T R +RE E
Sbjct: 254 RETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERER 313
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARRE 137
+ ++ R+ + ++++R+ KRK ++ER + + R + ++ RE
Sbjct: 314 NRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAER-ERE 372
Query: 138 WERQKRREMAREHSRRER 155
ER++ R+ ARE RER
Sbjct: 373 RERERDRQSAREREERER 390
Score = 53.1 bits (126), Expect = 9e-08
Identities = 46/146 (31%), Positives = 76/146 (52%), Gaps = 9/146 (6%)
Query: 17 LQEKKRRKEQEEKAEIKRL----KNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDS 72
L +RR +E + L K++D D +R+ +E E R + + T R + +RE
Sbjct: 24 LDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQ-TERETDRKRERR 82
Query: 73 ME-DRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERR-KRHREE 130
E DR + D + + +E+ R+ ++++EK ++ R KE+ERE ER +R R+
Sbjct: 83 REKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERN-RQKERERETEREGERGRDR 141
Query: 131 QDKARREWERQKRREMARE-HSRRER 155
Q +RE ERQ+ E RE + RER
Sbjct: 142 QTDGQRERERQRDAEKERERQTDRER 167
Score = 53.1 bits (126), Expect = 9e-08
Identities = 33/141 (23%), Positives = 73/141 (51%), Gaps = 9/141 (6%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSD-DRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
+EK+R ++ + + + +R K + ++ +R++ EGE R + + R+ D+ ++R
Sbjct: 101 REKERERQTDRERDRQREKERNRQKERERETEREGE-RGRDRQTDGQRERERQRDAEKER 159
Query: 77 GEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE----HERRKRHREEQD 132
+ D + +Q R + +++ R+E+R+ R +EKE + H R R RE +
Sbjct: 160 ERQTDR---ERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERER 216
Query: 133 KARREWERQKRREMAREHSRR 153
+ E ER+++ + R+ R+
Sbjct: 217 ETETETERKRQTDRERDRQRK 237
Score = 52.4 bits (124), Expect = 2e-07
Identities = 40/140 (28%), Positives = 70/140 (50%), Gaps = 8/140 (5%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGEL-RDHRMEITIRNSPYRREDSMEDR 76
+EK+R +++E + E +R + RD + D E E RD E + R+ + +R
Sbjct: 117 REKERNRQKERERETER-EGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNR 175
Query: 77 GEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARR 136
+E + + + R+E+ R+ E + E R R +E+ERE E + E + + R
Sbjct: 176 QKERE----REKNRQERRERERQREKENKTEDRHSERGRERERERET-ETETERKRQTDR 230
Query: 137 EWERQKRREMARE-HSRRER 155
E +RQ++ E RE + RER
Sbjct: 231 ERDRQRKTEREREKQAERER 250
Score = 51.2 bits (121), Expect = 3e-07
Identities = 38/148 (25%), Positives = 72/148 (48%), Gaps = 10/148 (6%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSD-DRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
++++RR E++ + E KR + + +R+ +R+ E E R R + RE E +
Sbjct: 285 RKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERK 344
Query: 77 GEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHRE------- 129
+ + + +Q R+ + ++ +R+ +R +E+E R R R+
Sbjct: 345 RKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQT 404
Query: 130 EQDK-ARREWERQKRREMAREHSR-RER 155
E+D+ +RE E+Q+ RE RE R RER
Sbjct: 405 EKDRDGQRETEKQREREKDRESERGRER 432
Score = 50.8 bits (120), Expect = 5e-07
Identities = 39/144 (27%), Positives = 73/144 (50%), Gaps = 9/144 (6%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSD---DRDSKRDSLEEGELRD--HRMEITIRN--SPYRRE 70
++K+R +E E + E R + +D +R+ +RD+ +E E + R T RN RE
Sbjct: 123 RQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERERE 182
Query: 71 DSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKE-KRKHARVKEKEREHERR-KRHR 128
+ ++R E + + + E+ R+ E+ E + + R ++ER+ +R+ +R R
Sbjct: 183 KNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERER 242
Query: 129 EEQDKARREWERQKRREMAREHSR 152
E+Q + R ER+ R+ RE R
Sbjct: 243 EKQAERERASERETERDKERERER 266
Score = 50.8 bits (120), Expect = 5e-07
Identities = 43/157 (27%), Positives = 77/157 (49%), Gaps = 8/157 (5%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSD-DRDSKRDSLEEGELRDHRMEIT 61
D K + + E ++++R++E+E + E R + + +R+ +R+ E E RD E
Sbjct: 284 DRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETE-RDREKERE 342
Query: 62 IRNSPYRREDSMEDR--GEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKER 119
+ D +R G E A + ++ +++ R+ E+R+ R R KE+ER
Sbjct: 343 RKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERER 402
Query: 120 EHERRKRHREEQDKARREWERQKRREMAREHSR-RER 155
+ E+ + + E +K R ER+K RE R R RER
Sbjct: 403 QTEKDRDGQRETEKQR---EREKDRESERGRERGRER 436
Score = 50.1 bits (118), Expect = 8e-07
Identities = 35/137 (25%), Positives = 67/137 (48%), Gaps = 5/137 (3%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSD---DRDSKRDSLEEGELRDHRMEITIRNSPYRREDSME 74
+E+ R++E+E + E +R + + DR+ +R+ + + R RR+ E
Sbjct: 311 RERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERE 370
Query: 75 -DRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDK 133
+R E D + + ++ R +K+ +R+ ++ +E E++ ER K E+ +
Sbjct: 371 RERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGR 430
Query: 134 AR-REWERQKRREMARE 149
R RE E+QK RE RE
Sbjct: 431 ERGREREKQKGRERDRE 447
Score = 35.0 bits (79), Expect = 0.026
Identities = 19/71 (26%), Positives = 31/71 (43%), Gaps = 3/71 (4%)
Query: 88 PQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMA 147
P SR+ +R + H +RE R+K ++K + E E ++RE
Sbjct: 23 PLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERR 82
Query: 148 RE---HSRRER 155
RE H +R+R
Sbjct: 83 REKDRHRKRDR 93
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 63.2 bits (152), Expect = 9e-11
Identities = 44/155 (28%), Positives = 76/155 (49%), Gaps = 14/155 (9%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITI 62
+E+ K K EI ++++R +E+E + E +R + +R+ +R+ +E E R
Sbjct: 292 EEEKGKKEKERQEI-EKERRERERERERERERREREREREREREREKEKERERERERDRD 350
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHE 122
R+ R+ DR E D + R+ + KD R ++ R +E+ERE E
Sbjct: 351 RDRTKERD---RDRDRERD-------RDRDRERSSDRNKDRSRSREKSRDRERERERERE 400
Query: 123 R---RKRHREEQDKARREWERQKRREMAREHSRRE 154
R R+R RE + + RE ER++ RE ++ R E
Sbjct: 401 REREREREREREREREREREREREREKDKKRDREE 435
Score = 56.6 bits (135), Expect = 8e-09
Identities = 43/149 (28%), Positives = 76/149 (51%), Gaps = 8/149 (5%)
Query: 9 KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYR 68
K + + L+E+K +KE+E + EI++ + +R+ +R E E R+ E +
Sbjct: 283 KFRDTHKKLEEEKGKKEKERQ-EIEKERRERERERER----ERERREREREREREREREK 337
Query: 69 REDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRK-HARVKEKEREHERRKRH 127
++ +R + D K + +E+ R E+ ++ K +R +EK R+ ER +R
Sbjct: 338 EKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRER-ERE 396
Query: 128 REEQDKARREWERQKRREMAREHSR-RER 155
RE + + RE ER++ RE RE R RER
Sbjct: 397 RERERERERERERERERERERERERERER 425
Score = 56.6 bits (135), Expect = 8e-09
Identities = 39/147 (26%), Positives = 71/147 (48%), Gaps = 10/147 (6%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSD-DRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
+EK+R +E+E + R K D DRD +RD + E R + R+ R+ E
Sbjct: 337 KEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERE 396
Query: 77 GEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKAR- 135
E + + ++ R+ + ++ +R++ +K R +++E +ERRK R+ ++K
Sbjct: 397 REREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAA 456
Query: 136 -----REW---ERQKRREMAREHSRRE 154
+ W ER+K RE +E R E
Sbjct: 457 YQERLKNWEIRERKKTREYEKEAEREE 483
Score = 55.8 bits (133), Expect = 1e-08
Identities = 39/139 (28%), Positives = 68/139 (48%), Gaps = 14/139 (10%)
Query: 18 QEKKRRKEQE-EKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
+E++R +E+E E+ + K + +RD RD +E + RD E R D +DR
Sbjct: 323 REREREREREREREKEKERERERERDRDRDRTKERD-RDRDRERDRDRDRERSSDRNKDR 381
Query: 77 GEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARR 136
++ SR + ++ +R+ +R+ R +E+ERE ER + E+DK R
Sbjct: 382 SRS---------REKSRDREREREREREREREREREREREREREREREREREREKDKKR- 431
Query: 137 EWERQKRREMAREHSRRER 155
+R++ E A E + ER
Sbjct: 432 --DREEDEEDAYERRKLER 448
Score = 53.9 bits (128), Expect = 5e-08
Identities = 37/149 (24%), Positives = 66/149 (44%), Gaps = 1/149 (0%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIR 63
++D + K D ++ R E++ + S R+ RD E E R+ E
Sbjct: 348 DRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERE-RERERERERE 406
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHER 123
R + +R E + K + +E A+ R+ +RK + K A +E+ + E
Sbjct: 407 REREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEI 466
Query: 124 RKRHREEQDKARREWERQKRREMAREHSR 152
R+R + + + E E ++RREMA+E R
Sbjct: 467 RERKKTREYEKEAEREEERRREMAKEAKR 495
Score = 49.7 bits (117), Expect = 1e-06
Identities = 46/157 (29%), Positives = 73/157 (46%), Gaps = 17/157 (10%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKN---------SDDRDS----KRDSLEEGELRDHRMEI 60
+E L E+ +R++Q K I+ L S + DS K+ +E R +
Sbjct: 193 EEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAP 252
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE 120
I +ED EED I +++S+ H + +E++ +K K + EKER
Sbjct: 253 LIPYPLITKEDINAIEMEEDKRDLIS--REISKFRDTHKKLEEEKGKKEKERQEIEKERR 310
Query: 121 HERRKRHREEQDKAR-REWERQKRREMAREHSR-RER 155
R+R RE + + R RE ER++ RE +E R RER
Sbjct: 311 ERERERERERERREREREREREREREKEKERERERER 347
Score = 47.4 bits (111), Expect = 5e-06
Identities = 39/145 (26%), Positives = 67/145 (46%), Gaps = 16/145 (11%)
Query: 26 QEEKAEIKRLKNSDDRDS-KRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLA 84
+E+K ++ + S RD+ K+ E+G+ R EI RE E E +
Sbjct: 270 EEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERER 329
Query: 85 IKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHER-------------RKRHREEQ 131
+ ++ KE+ R+ ++ +++ K R ++++RE +R R R RE+
Sbjct: 330 EREREREKEKERERERERDRDRDRTKE-RDRDRDRERDRDRDRERSSDRNKDRSRSREKS 388
Query: 132 DKARREWERQKRREMAREHSR-RER 155
RE ER++ RE RE R RER
Sbjct: 389 RDRERERERERERERERERERERER 413
Score = 40.8 bits (94), Expect = 5e-04
Identities = 42/176 (23%), Positives = 76/176 (43%), Gaps = 31/176 (17%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGEL-RDHRMEIT 61
DE+D+++ + L+ L+EK E A +RLKN + R+ K+ E E R+
Sbjct: 436 DEEDAYERRKLERKLREK-------EAAYQERLKNWEIRERKKTREYEKEAEREEERRRE 488
Query: 62 IRNSPYRREDSMEDRGEEDDS------LAIKPPQQMSRKEKAHHRKDEKR-KEKRKHARV 114
+ R ++ +ED ++ D A++ + KE +D KR KE+ + R
Sbjct: 489 MAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQ 548
Query: 115 K----------------EKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
+ E+E E R+ + ++E + E E+Q++ E E E
Sbjct: 549 RLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEE 604
Score = 39.7 bits (91), Expect = 0.001
Identities = 34/152 (22%), Positives = 68/152 (44%), Gaps = 25/152 (16%)
Query: 7 SWKVKTLDEILQEKKRRKEQEEKA-----EIKRLKN-----SDDRDSK---RDSLEEGEL 53
+W+++ + + +K + +EE+ E KRLK DDRD R S + L
Sbjct: 463 NWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRL 522
Query: 54 RDHRMEITIRNSPYRRE-DSMED-------RGEEDDSLAIKPPQQMSRKEKAHHRKDEKR 105
RD E+ +RE + +E+ G D ++ +Q + + + K E
Sbjct: 523 RDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPE 582
Query: 106 KEKRKHARVKEKEREHERRKRHREEQDKARRE 137
E+ + +EK+ + E+R+ EE+++ ++
Sbjct: 583 SEEEE----EEKQEKEEKREEPMEEEEEPEQK 610
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 61.6 bits (148), Expect = 3e-10
Identities = 42/167 (25%), Positives = 80/167 (47%), Gaps = 19/167 (11%)
Query: 3 DEKDSWKVKTLDEILQEKKR----------RKEQE--EKAEIKRLKNSDDRDSKRDSLEE 50
+EK + + D + QE++ RKE+E ++ E +R + + + + LE
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283
Query: 51 GELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRK 110
ELR R E + RRE + + EE+ + QQ R+E+ R+ ++ + +++
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQEEE-----RREQQEERREQQERREQQEERREQQ 338
Query: 111 HARVKEKEREHERRKRHREE--QDKARREWERQKRREMAREHSRRER 155
R +E+ RE + R+ EE + + RRE E ++R + R + R
Sbjct: 339 LRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385
Score = 61.2 bits (147), Expect = 3e-10
Identities = 34/158 (21%), Positives = 84/158 (53%), Gaps = 6/158 (3%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
+G+E+++ + + L+ ++++ +++EE+ + + ++ +R EE EL+ ++
Sbjct: 1064 LGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL 1123
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKE-- 118
RR +E + E++ + + +Q+ R+E R+ E ++ R+ ++++E
Sbjct: 1124 LREEREKRRRQELERQYREEEEVQ-QEEEQLLREEPEKRRRQELERQYREEEELQQEEEQ 1182
Query: 119 ---REHERRKRHREEQDKARREWERQKRREMAREHSRR 153
E E+R++ RE Q + E +RQKR++ R+ +R
Sbjct: 1183 LLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQR 1220
Score = 59.3 bits (142), Expect = 1e-09
Identities = 46/144 (31%), Positives = 79/144 (54%), Gaps = 9/144 (6%)
Query: 11 KTLDEILQEKKRRKEQEEKAE--IKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYR 68
K L++ +E++ ++EQEE+ + +KR + + KR+ E E R R E+ R
Sbjct: 556 KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEER 615
Query: 69 REDSM--EDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKR 126
RE + E+ EE +K +Q R+++ R+ ++R+E+R R +E+ER +R KR
Sbjct: 616 REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLK-REEEEERLEQRLKR 674
Query: 127 HREEQDKARREWE-RQKRREMARE 149
EE+ RRE E ++ +E ARE
Sbjct: 675 EHEEE---RREQELAEEEQEQARE 695
Score = 58.5 bits (140), Expect = 2e-09
Identities = 37/141 (26%), Positives = 73/141 (51%), Gaps = 4/141 (2%)
Query: 17 LQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRM--EITIRNSPYRREDSME 74
L+E++RR++QE + + R + + R+ + EE E R+ E +R R + +
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLL 550
Query: 75 DRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKA 134
R EE + Q++ R+++ + KR+E+R+ R+K ++ E ++ REE ++
Sbjct: 551 KREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERL 610
Query: 135 RREWERQKRREMAREHSRRER 155
+E R++R + RE ER
Sbjct: 611 EQEERREQR--LKREEPEEER 629
Score = 57.8 bits (138), Expect = 4e-09
Identities = 40/158 (25%), Positives = 81/158 (51%), Gaps = 7/158 (4%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSL-EEGELRDHRMEIT 61
+E+ +++ E +E++ R+EQEE+ ++L+ + + + L E +LR R +
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR--REQQL 389
Query: 62 IRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKE---KE 118
R RRE + + ++ QQ+ R+++ ++E+R E++ +E K
Sbjct: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
Query: 119 REHERRKRHREEQDKARREWERQKRR-EMAREHSRRER 155
+ ERR + E++ R E ER+K++ + +E RRER
Sbjct: 450 EQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Score = 57.8 bits (138), Expect = 4e-09
Identities = 50/166 (30%), Positives = 80/166 (48%), Gaps = 19/166 (11%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRD------SLEEGELRDH- 56
E+ ++K E ++ +R+E+ E+ E +R K RD + + LEE E R+
Sbjct: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQ 500
Query: 57 -RMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKE---KRKHA 112
R E +R R + R EE++ L QQ R E+ R+ E+R+E KR+
Sbjct: 501 ERREQQLRREQEERREQRLKRQEEEERL-----QQRLRSEQQLRREQEERREQLLKREEE 555
Query: 113 RVKEKEREHERRKRHREE---QDKARREWERQKRREMAREHSRRER 155
+ E+ER +R KR +EE Q R E RQ+R + +E +R
Sbjct: 556 KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQR 601
Score = 57.4 bits (137), Expect = 5e-09
Identities = 41/140 (29%), Positives = 76/140 (54%), Gaps = 8/140 (5%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRD--HRMEITIRNSPYRREDSMED 75
+++ RR+++EE+ E K+ +R +R E+ E RD R E T R+ RR+ ++
Sbjct: 422 EQQLRREQEEERHE---QKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 478
Query: 76 RGEEDDSLAIKPPQQMSRKEKAHHRKDEKRK--EKRKHARVKEKEREHERRKRHREEQDK 133
EE+ ++ R+E+ R+ + R+ E+R+ R+K +E E ++R R EQ +
Sbjct: 479 DQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQ-Q 537
Query: 134 ARREWERQKRREMAREHSRR 153
RRE E ++ + + RE +R
Sbjct: 538 LRREQEERREQLLKREEEKR 557
Score = 57.4 bits (137), Expect = 5e-09
Identities = 46/157 (29%), Positives = 79/157 (50%), Gaps = 17/157 (10%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRD--HRMEI 60
+E+ W + + E++RRK+Q +KR ++R + LEE E R+ R E
Sbjct: 452 EERRDWLKREEETERHEQERRKQQ-----LKR-DQEEERRERWLKLEEEERREQQERREQ 505
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKE---KRKHARVKEK 117
+R R + R EE++ L QQ R E+ R+ E+R+E KR+ + E+
Sbjct: 506 QLRREQEERREQRLKRQEEEERL-----QQRLRSEQQLRREQEERREQLLKREEEKRLEQ 560
Query: 118 EREHERRKRHREE-QDKARREWERQKRREMAREHSRR 153
ER +R KR +EE +D+ + E ++++ + RE R
Sbjct: 561 ERREQRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Score = 57.4 bits (137), Expect = 5e-09
Identities = 39/152 (25%), Positives = 83/152 (54%), Gaps = 12/152 (7%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSD----DRDSKRDSL----EEGELRDHRMEITIRNS 65
+E +++ +R+E+EE+ + +RL++ +++ +R+ L EE L R E ++
Sbjct: 512 EERREQRLKRQEEEERLQ-QRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE 570
Query: 66 PYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEK-RKEKRKHARVKEKEREHERR 124
R D + R EE +K Q+ +++ + E+ +E+R+ R+K +E E ERR
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERR 630
Query: 125 KR--HREEQDKARREWERQKRREMAREHSRRE 154
++ EEQ++ R++ R++++E + +RE
Sbjct: 631 QQLLKSEEQEERRQQQLRREQQERREQRLKRE 662
Score = 57.4 bits (137), Expect = 5e-09
Identities = 40/172 (23%), Positives = 87/172 (50%), Gaps = 32/172 (18%)
Query: 14 DEILQEKKRRKEQEEKAEIK-RLKNSDDRDSKRDSL------------EEGELRDHRMEI 60
D + ++++RR+ QE++ + K R + ++R +R +L E+ L++ E+
Sbjct: 854 DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEEL 913
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKE-- 118
RR E + E++ L + +Q+ R+E+ R+ E+ ++ RK ++++KE
Sbjct: 914 QREEREKRRRQEQERQYREEEQLQ-QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ 972
Query: 119 ---------REHERRKRHREEQD-------KARREWERQKRREMAREHSRRE 154
R ER K++REE++ R E E+++R+E R++ +++
Sbjct: 973 LLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKD 1024
Score = 57.0 bits (136), Expect = 6e-09
Identities = 38/145 (26%), Positives = 72/145 (49%), Gaps = 13/145 (8%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+E+ R EQEE+ E +RLK + + +R L + E ++ R + +R R + R
Sbjct: 604 REEVERLEQEERRE-QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKER--------EHERRKRHRE 129
EE++ L Q++ R+ + R+ E +E+++ AR + K R E E R +
Sbjct: 663 EEEERLE----QRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSK 718
Query: 130 EQDKARREWERQKRREMAREHSRRE 154
+ R++ +++R+E + RRE
Sbjct: 719 VYSRPRKQEGQRRRQEQEEKRRRRE 743
Score = 56.6 bits (135), Expect = 8e-09
Identities = 35/160 (21%), Positives = 77/160 (48%), Gaps = 12/160 (7%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITI 62
+ ++ + + E +E++ R+EQEE+ E ++L+ + + + L + + R +
Sbjct: 320 ERREQQERREQQEERREQQLRREQEERRE-QQLRREQEEERREQQLRREQEEERREQQLR 378
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKR-------KEKRKHARVK 115
R RRE + + ++ QQ+ R+++ + +R +E+ +H +
Sbjct: 379 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKH 438
Query: 116 EKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 155
E+ER +R KR +EE RR+W +++ E RR++
Sbjct: 439 EQERREQRLKREQEE----RRDWLKREEETERHEQERRKQ 474
Score = 55.8 bits (133), Expect = 1e-08
Identities = 41/143 (28%), Positives = 75/143 (52%), Gaps = 9/143 (6%)
Query: 18 QEKKRRKEQ---EEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSME 74
Q ++R KE EE+ +++R + + + D L+E + R E R R E
Sbjct: 823 QRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQ--RRDQKWRWQLEE 880
Query: 75 DRGEEDDSLAIKPP-QQMSRKEKA--HHRKDEKRKEKRKHARVKEKEREHERRKRHREEQ 131
+R +L KP Q+ RKE+ ++E ++E+R+ R +E+ER++ ++ ++E+
Sbjct: 881 ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE 940
Query: 132 DKARREWERQKRREMAREHSRRE 154
++ RE ER+KRR RE R+
Sbjct: 941 EQLLRE-EREKRRRQERERQYRK 962
Score = 53.9 bits (128), Expect = 5e-08
Identities = 36/145 (24%), Positives = 80/145 (55%), Gaps = 13/145 (8%)
Query: 13 LDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDS 72
L ++ +++ RR+ QEE+ + +RL+ R+ + +E E R+ + E R R +
Sbjct: 278 LRKLERQELRRERQEEEQQQQRLR----REQQLRRKQEEERREQQEE---RREQQERREQ 330
Query: 73 MEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHE-RRKRHREEQ 131
E+R E+ ++ Q+ R+++ ++E+R+E++ +E+ RE + RR++ +
Sbjct: 331 QEERREQQ----LRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 132 DKARREWERQKRREMAREHS-RRER 155
+ RRE + ++ +++ RE RRE+
Sbjct: 387 QQLRREQQLRREQQLRREQQLRREQ 411
Score = 53.9 bits (128), Expect = 5e-08
Identities = 41/159 (25%), Positives = 77/159 (48%), Gaps = 22/159 (13%)
Query: 17 LQEKKRRKEQ---EEKAEIKRLKNSDDR--DSKRDSLEEGELRDHRMEITIRNSPYRRED 71
LQE+ R+++Q EE+ E++R + R + +R EE +L+ ++ RR
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQ 954
Query: 72 SMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRK----------------EKRKHARVK 115
E + +D L K Q + + + R++ ++K E+R+ R +
Sbjct: 955 ERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ 1014
Query: 116 EKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
E ER++ ++ ++E+++ RE ER+KRR RE RE
Sbjct: 1015 EWERQYRKKDELQQEEEQLLRE-EREKRRLQERERQYRE 1052
Score = 53.5 bits (127), Expect = 7e-08
Identities = 39/143 (27%), Positives = 78/143 (54%), Gaps = 12/143 (8%)
Query: 18 QEKKRRKEQEEKAE-IKRLKNSDDRDSKRDSLEEGELRDHRM----EITIRNSPYRREDS 72
QE++RR++QEE+ E +R + ++R ++ E+ E R+ ++ E R RRE
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQE 369
Query: 73 MEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQD 132
E R ++ ++ QQ+ R+++ + +R+++ + + +E++ R ++ R EQ
Sbjct: 370 EERREQQ-----LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ- 423
Query: 133 KARREWERQKRREMAREHSRRER 155
+ RRE E ++R E E RRE+
Sbjct: 424 QLRREQE-EERHEQKHEQERREQ 445
Score = 53.1 bits (126), Expect = 9e-08
Identities = 39/171 (22%), Positives = 89/171 (52%), Gaps = 17/171 (9%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQE-----EKAEIKRLKNSDDRDSKRDSLEEGE--- 52
+G+E + + + ++ +E++ +++E E+ E +R + + + K+D L++ E
Sbjct: 974 LGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQL 1033
Query: 53 LRDHR--MEITIRNSPYRREDSMEDR-----GEEDDSLAIKPPQQMSRKEKAHHRKDEK- 104
LR+ R + R YR E+ ++ GEE ++ + ++ RKE+ +++E+
Sbjct: 1034 LREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQL 1093
Query: 105 -RKEKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
R+E K R + + + E + +EE+ R E E+++R+E+ R++ E
Sbjct: 1094 LREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEE 1144
Score = 52.8 bits (125), Expect = 1e-07
Identities = 35/151 (23%), Positives = 75/151 (49%), Gaps = 10/151 (6%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSM 73
DE+ QE+++ +E + + + R+ + EE +L E R R+
Sbjct: 1024 DELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKE 1083
Query: 74 EDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKR---------KEKRKHARVKEKEREH-ER 123
E+ +E++ L + P++ R+E+ ++E+ +E+R+ R +E ER++ E
Sbjct: 1084 EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREE 1143
Query: 124 RKRHREEQDKARREWERQKRREMAREHSRRE 154
+ +EE+ R E E+++R+E+ R++ E
Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQELERQYREEE 1174
Score = 52.4 bits (124), Expect = 2e-07
Identities = 43/162 (26%), Positives = 79/162 (48%), Gaps = 23/162 (14%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRD--HRMEITIRNSPYRREDS 72
++ +E++ R+EQEE E K+ +R +R E+ E RD R E T R+ RR+
Sbjct: 418 QLRREQQLRREQEE--ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475
Query: 73 MEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEK--RKHARVKEKEREHERRKRHREE 130
++ EE+ ++ R+E+ R+ + R+E+ R+ R+K +E E ++R R E
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE 535
Query: 131 Q-----------------DKARREWERQKRREMAREHSRRER 155
Q ++ R E ER+++R + RR++
Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ 577
Score = 52.0 bits (123), Expect = 2e-07
Identities = 36/144 (25%), Positives = 80/144 (55%), Gaps = 6/144 (4%)
Query: 14 DEILQEKKRRKEQEEK-AEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDS 72
+E+ ++++ +E+EE+ AE ++L++ +++ EE R +E+ + RE+
Sbjct: 171 EELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKG----REEK 226
Query: 73 MEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHER-RKRHREEQ 131
+ R E D + + ++ RK + RK+E++ ++ + R +E + E E+ RK R+E
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL 286
Query: 132 DKARREWERQKRREMAREHSRRER 155
+ R+E E+Q++R + RR++
Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQ 310
Score = 52.0 bits (123), Expect = 2e-07
Identities = 34/148 (22%), Positives = 76/148 (51%), Gaps = 18/148 (12%)
Query: 18 QEKKRRKEQEE--------KAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRR 69
QE +R +++EE + +++R + + R+ + + E+ E R+ + E RR
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE--------RR 335
Query: 70 EDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHE-RRKRHR 128
E + EE ++ Q+ R+E+ R+ E+ + +++ R ++ RE + RR++
Sbjct: 336 EQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQL 395
Query: 129 EEQDKARREWERQKRREMAREHS-RRER 155
+ + RRE + ++ +++ RE RRE+
Sbjct: 396 RREQQLRREQQLRREQQLRREQQLRREQ 423
Score = 50.8 bits (120), Expect = 5e-07
Identities = 38/147 (25%), Positives = 81/147 (55%), Gaps = 18/147 (12%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+E+++R+ QE + + ++ K ++ + EE E R R E R YR E+ ++
Sbjct: 946 EEREKRRRQERERQYRKDKKLQQKEEQLLG-EEPEKR-RRQE---REKKYREEEELQ--- 997
Query: 78 EEDDSLAIKPPQQMSRKE--KAHHRKDEKRKEKRKHARV-KEKEREHERRKRHREEQDKA 134
+E++ L + ++ R+E + + +KDE ++E+ + R +EK R ER +++REE++
Sbjct: 998 QEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQ 1057
Query: 135 R-------REWERQKRREMAREHSRRE 154
+ E E ++R+E+ R++ + E
Sbjct: 1058 QEEEQLLGEERETRRRQELERQYRKEE 1084
Score = 50.4 bits (119), Expect = 6e-07
Identities = 35/143 (24%), Positives = 72/143 (50%), Gaps = 10/143 (6%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+E++ R E+ ++ E + L ++++ +R E R+ ++ +R + +
Sbjct: 794 RERQLRAEERQQREQRFLPEEEEKEQRRRQRRE---REKELQFLEEEEQLQRRERAQQLQ 850
Query: 78 EEDDSL----AIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRH--REEQ 131
EE+D L + Q+ R +K + +E+RK +R K +E R+++ +EE+
Sbjct: 851 EEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEE 910
Query: 132 DKARREWERQKRREMAREHSRRE 154
++ +RE ER+KRR +E RE
Sbjct: 911 EELQRE-EREKRRRQEQERQYRE 932
Score = 50.4 bits (119), Expect = 6e-07
Identities = 39/162 (24%), Positives = 79/162 (48%), Gaps = 25/162 (15%)
Query: 17 LQEKKR--RKEQEEKAEIKRLKNSDDRDSKRDSLE-----EGELRDHRMEITIRNSPYRR 69
LQE++R R+E+E + E ++L + +R LE E EL+ ++ RR
Sbjct: 1043 LQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102
Query: 70 EDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKER-----EHERR 124
E + E++ L + +Q+ R+E+ R+ E ++ R+ V+++E E E+R
Sbjct: 1103 RQERERQCREEEELQ-QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161
Query: 125 KRH------------REEQDKARREWERQKRREMAREHSRRE 154
+R ++E+++ RE + ++R+E R++ E
Sbjct: 1162 RRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEE 1203
Score = 50.1 bits (118), Expect = 8e-07
Identities = 41/165 (24%), Positives = 87/165 (52%), Gaps = 19/165 (11%)
Query: 4 EKDSWKVKTLDEILQEKK-RRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITI 62
E+D + + D L+E+ +R+ Q+ + + + L +++ K++ LE+ + + E+
Sbjct: 116 EEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWR 175
Query: 63 RNSPYRREDSMEDRGEEDDSLAIK--------PPQQMSRKEKAHHR---KDEKRKEKR-K 110
+ ++ + E R EE+ + K +Q+ R+E R ++EK++++R +
Sbjct: 176 QRQEWQERE--ERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRER 233
Query: 111 HARVKEKEREHERRKRH---REEQDKARREWERQKRREMAREHSR 152
RV ++E E E RKR R+E++K + E E Q++RE+ E +
Sbjct: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEE-EPQRQRELQEEEEQ 277
Score = 50.1 bits (118), Expect = 8e-07
Identities = 30/135 (22%), Positives = 73/135 (54%), Gaps = 11/135 (8%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLE-----EGELRDHRMEITIRNSPYRREDS 72
+E++ R+E+E + E ++L + +R LE E E++ ++ RR
Sbjct: 1106 RERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQE 1165
Query: 73 MEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQD 132
+E + E++ L + +Q+ R+E+ +++R+E+ + R +E+ + +R++R+R+E
Sbjct: 1166 LERQYREEEELQ-QEEEQLLREEQ-----EKRRQERERQYREEEELQRQKRKQRYRDEDQ 1219
Query: 133 KARREWERQKRREMA 147
++ +W+ + +E A
Sbjct: 1220 RSDLKWQWEPEKENA 1234
Score = 50.1 bits (118), Expect = 8e-07
Identities = 40/155 (25%), Positives = 80/155 (51%), Gaps = 17/155 (10%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSD----DRDSK----RDSLEEGELRDHRMEITIRNSP 66
++ ++++ RK EE+ +++R + DRD K L+EGE + R + R
Sbjct: 1635 QLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKF- 1693
Query: 67 YRREDSMEDRGEEDDSLAIKPPQQMSRKE-KAHHRKDEKRKEKRKHARVKEKER-----E 120
RE+ + R +E + ++ QQ+ R+E + R++E+ +++ + +++ +ER E
Sbjct: 1694 --REEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILE 1751
Query: 121 HERRKRHREEQDKARREWERQKRREMAREHSRRER 155
E+ + REEQ R+E +R+ R E R E+
Sbjct: 1752 EEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQ 1786
Score = 49.7 bits (117), Expect = 1e-06
Identities = 36/159 (22%), Positives = 82/159 (51%), Gaps = 8/159 (5%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQE-EKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEIT 61
+E+ ++++ ++ +E++ R+EQ ++ E KRL+ +R +R E+ E RD ++
Sbjct: 525 EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ--ERREQRLKREQEERRDQLLKRE 582
Query: 62 IRNSPYR----REDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEK 117
R +E+ +E R + ++ ++ ++ ++ K ++E+R++ K +E+
Sbjct: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642
Query: 118 EREHERR-KRHREEQDKARREWERQKRREMAREHSRRER 155
++ RR ++ R EQ R E E + + + REH R
Sbjct: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERR 681
Score = 49.3 bits (116), Expect = 1e-06
Identities = 33/158 (20%), Positives = 76/158 (48%), Gaps = 8/158 (5%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITI 62
+E+ +++ + +E++ ++E+EE+ +RLK + + + L E E R I
Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHE 122
R ++ + +E + S P++ ++ ++EKR+ + + +E+ER H
Sbjct: 700 RIPKWQWQ--LESEADARQSKVYSRPRK-QEGQRRRQEQEEKRRRRESELQWQEEERAHR 756
Query: 123 RRKRHREEQD-----KARREWERQKRREMAREHSRRER 155
+++ + +D +A + ER ++R AR R +R
Sbjct: 757 QQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQR 794
Score = 49.3 bits (116), Expect = 1e-06
Identities = 38/152 (25%), Positives = 79/152 (51%), Gaps = 11/152 (7%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSL--EEGELRDHRMEITIRNSPYRREDS 72
++ +++++RK +E+ +++R + R RD EE +LR R E + R+
Sbjct: 1523 QLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFR 1582
Query: 73 MED---RGEEDDSLAIKPPQQMSRKE---KAHHRKDEKRKEKRKHARVKEKEREH--ERR 124
+E+ R +E + ++ QQ+ R+E + +D K +E + + +E+++ H ER
Sbjct: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERD 1642
Query: 125 KRHREEQDKARR-EWERQKRREMAREHSRRER 155
++ EE+ + RR E E+Q R + R+ E+
Sbjct: 1643 RKFLEEEPQLRRQEREQQLRHDRDRKFREEEQ 1674
Score = 48.9 bits (115), Expect = 2e-06
Identities = 40/158 (25%), Positives = 81/158 (51%), Gaps = 16/158 (10%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIR 63
E+ S K + L+ Q ++R+++E + + + ++R ++ + L+ + H E
Sbjct: 152 EEQSEKQERLE---QRDRQRRDEELWRQRQEWQEREERRAEEEQLQS--CKGHETEEFPD 206
Query: 64 NSPYRREDSMEDR--GEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKER-- 119
RR + +E R G E+ K Q+ R+++ ++EK KR+ KE+E+
Sbjct: 207 EEQLRRRELLELRRKGREE-----KQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ 261
Query: 120 -EHERRKRHREEQDKARREWERQK-RREMAREHSRRER 155
E +R+R +E+++ R+ ERQ+ RRE E +++R
Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQR 299
Score = 48.9 bits (115), Expect = 2e-06
Identities = 37/163 (22%), Positives = 77/163 (47%), Gaps = 15/163 (9%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIR 63
E+ + + ++ L++ + RK +EE+ ++ R +RD K E+ R R +
Sbjct: 1395 EEQQLRCQEREQQLRQDRDRKFREEEQQLSR----QERDRKFREEEQQVRRQERERKFLE 1450
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAH---------HRKDEKRKEKRKHARV 114
R++ EE+ L + QQ+ R+E+ R++ RK + + R
Sbjct: 1451 EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRS 1510
Query: 115 KEKERE--HERRKRHREEQDKARREWERQKRREMAREHSRRER 155
+E ER+ E ++ HR+++ + + E+Q RR+ + R++R
Sbjct: 1511 QEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDR 1553
Score = 48.9 bits (115), Expect = 2e-06
Identities = 33/147 (22%), Positives = 78/147 (53%), Gaps = 13/147 (8%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSME 74
++ ++++ RK EE+ ++++ ++ R+ ++ E E + HR E R+ + E+
Sbjct: 1438 QVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQE---RDRKFLEEEQQL 1494
Query: 75 DRGEEDDSL------AIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHR 128
R E D + +P ++ +E+ HR+ +RK ++ +++ +ER +R R
Sbjct: 1495 RRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQR----R 1550
Query: 129 EEQDKARREWERQKRREMAREHSRRER 155
+++D+ RE E+ ++ ++ SR+ER
Sbjct: 1551 QDRDRKFREEEQLRQEREEQQLSRQER 1577
Score = 48.9 bits (115), Expect = 2e-06
Identities = 38/159 (23%), Positives = 83/159 (52%), Gaps = 18/159 (11%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIR 63
E+ + + L+ +E+++ +++ E+ +++R ++ R LEE +LR R E +R
Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQLRR------QERYRKILEEEQLRPEREEQQLR 1765
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE--- 120
R+E + R EE + Q S++ R++E+ +++R+ +++ ++R+
Sbjct: 1766 ----RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKY 1821
Query: 121 --HERRKRHREEQDKARREWERQKRRE---MAREHSRRE 154
E + + E++ + R+E +RQ R E +E SRRE
Sbjct: 1822 RWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRRE 1860
Score = 48.5 bits (114), Expect = 2e-06
Identities = 35/146 (23%), Positives = 72/146 (49%), Gaps = 5/146 (3%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSDDRDSK--RDSLEEGELRDHRMEITIRNSPYRREDS 72
+IL+E++ R E+EE+ ++ ++ R+ + R EE +LR + R R++
Sbjct: 1748 KILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQER 1807
Query: 73 MED--RGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREH-ERRKRHRE 129
E R ++ D +Q+ +E+ + E+ ++ R + +E+ E ++ +E
Sbjct: 1808 EEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQE 1867
Query: 130 EQDKARREWERQKRREMAREHSRRER 155
E+ K R+E ER+ R E R + E+
Sbjct: 1868 EEQKRRQERERKLREEHIRRQQKEEQ 1893
Score = 48.1 bits (113), Expect = 3e-06
Identities = 36/157 (22%), Positives = 81/157 (51%), Gaps = 13/157 (8%)
Query: 5 KDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLE-EGELRDHRMEITIR 63
K W++++ + Q K + ++++ + +R + + R + L+ + E R HR + +
Sbjct: 703 KWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ---Q 759
Query: 64 NSPYRREDSMEDRGEEDDS-----LAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKE 118
RR+ + + + EE L+ +PP R+++ + E+R+++ + +E+E
Sbjct: 760 EEEQRRDFTWQWQAEEKSERGRQRLSARPPL---REQRERQLRAEERQQREQRFLPEEEE 816
Query: 119 REHERR-KRHREEQDKARREWERQKRREMAREHSRRE 154
+E RR +R RE++ + E E+ +RRE A++ E
Sbjct: 817 KEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
Score = 47.8 bits (112), Expect = 4e-06
Identities = 36/144 (25%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPY---RREDSME 74
+++K R+E++ + E + + S ++ LEE ++R E R+E +
Sbjct: 1553 RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612
Query: 75 DRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE----HERRKRHREE 130
R E D R+E+ HR++ RK + +++ +ERE H+R ++ REE
Sbjct: 1613 LRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREE 1672
Query: 131 QDKARREWERQKRREMAREHSRRE 154
++ +E E Q+ R R+ RE
Sbjct: 1673 -EQLLQEGEEQQLRRQERDRKFRE 1695
Score = 46.6 bits (109), Expect = 9e-06
Identities = 22/86 (25%), Positives = 47/86 (54%), Gaps = 5/86 (5%)
Query: 69 REDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHER----- 123
+E ++DR +E+D +P + +E R+ ++++++R+ A +E+ + ER
Sbjct: 106 KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRD 165
Query: 124 RKRHREEQDKARREWERQKRREMARE 149
R+R EE + R+EW+ ++ R E
Sbjct: 166 RQRRDEELWRQRQEWQEREERRAEEE 191
Score = 46.6 bits (109), Expect = 9e-06
Identities = 37/166 (22%), Positives = 78/166 (46%), Gaps = 24/166 (14%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSL---EEGELRDHRMEITIRNSPYRRE 70
++ L++++ RK +EE+ ++ + +RD EE +LR + R R +
Sbjct: 1452 EQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQ 1511
Query: 71 DSMEDRGEEDDSLA--------IKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHE 122
+ EE+ L ++ QQ+ R+E+ R+ ++ ++ R+ +++++ E +
Sbjct: 1512 EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQ 1571
Query: 123 RRKRHR------EEQDKARREWER-------QKRREMAREHSRRER 155
++ R EEQ R+E ER Q RR+ ++ R+ER
Sbjct: 1572 LSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQER 1617
Score = 46.6 bits (109), Expect = 9e-06
Identities = 35/138 (25%), Positives = 70/138 (50%), Gaps = 8/138 (5%)
Query: 18 QEKKRRKEQEEKAEIKRLKNS-DDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
QE+ R+ +EE+ +R + ++S R EE +LR R E +R P +R+
Sbjct: 1767 QERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLR--PQQRDGKYR-- 1822
Query: 77 GEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARR 136
E++ L ++ +Q R+E+ + E++ ++ +R +E+E E ++ R+E+++ R
Sbjct: 1823 -WEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLR 1881
Query: 137 EWERQKRREMAREHSRRE 154
E RR+ E R+
Sbjct: 1882 E--EHIRRQQKEEQRHRQ 1897
Score = 46.2 bits (108), Expect = 1e-05
Identities = 37/156 (23%), Positives = 77/156 (49%), Gaps = 19/156 (12%)
Query: 18 QEKKRRKEQEEK-AEIKRLKNSDDR------------DSKRDSLEEGELRDHRMEITIRN 64
+EK+RR+E+E + + K+L+ +++ + ++ EE EL+ ++
Sbjct: 948 REKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREE 1007
Query: 65 SPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE---H 121
RR E + + D L + +Q+ R+E+ R E+ ++ R+ ++++E +
Sbjct: 1008 REKRRRQEWERQYRKKDELQ-QEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE 1066
Query: 122 ERRKRHREEQDKA-RREWERQKRRE-MAREHSRRER 155
ER R R+E ++ R+E E Q+ E + RE + R
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102
Score = 46.2 bits (108), Expect = 1e-05
Identities = 39/158 (24%), Positives = 75/158 (47%), Gaps = 9/158 (5%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEK-AEIKRLKNSDDRDSKRDSLEEGELRDHRMEIT 61
D K + + L E +EK+RR+E + K E ++L + R + + R+ +
Sbjct: 1311 DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQ 1370
Query: 62 IRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHH-RKDEKRKEKRKHARVKEKERE 120
+ + E+ R E + +K QQ+ +E+ R+D RK + + ++ +ER+
Sbjct: 1371 EQGRKFLEEEQRLRRQERERKF-LKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD 1429
Query: 121 HERRKRHREEQDKARREWER---QKRREMAREHSRRER 155
RK EEQ R+E ER ++ +++ +E R+ R
Sbjct: 1430 ---RKFREEEQQVRRQERERKFLEEEQQLRQERHRKFR 1464
Score = 45.4 bits (106), Expect = 2e-05
Identities = 35/137 (25%), Positives = 70/137 (51%), Gaps = 15/137 (10%)
Query: 22 RRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG--EE 79
RRK +EEK + +R + +D EE E R + + E+ R EE
Sbjct: 219 RRKGREEKQQQRR----ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE 274
Query: 80 DDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARREWE 139
++ L +++ R+E R++E+++++R + + ++ E R+ E+Q++ R + E
Sbjct: 275 EEQL-----RKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERR---EQQEERREQQE 326
Query: 140 RQKRREMAREHS-RRER 155
R++++E RE RRE+
Sbjct: 327 RREQQEERREQQLRREQ 343
Score = 45.4 bits (106), Expect = 2e-05
Identities = 38/171 (22%), Positives = 83/171 (48%), Gaps = 25/171 (14%)
Query: 9 KVKTLDEILQEKK----RRKEQEEKAEIKRLKNSD--------DRDSKRDSLEEGELRDH 56
K + +++LQE++ RR+E++ K + L++ + ++ +R E L++
Sbjct: 1337 KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEE 1396
Query: 57 RMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKE--------- 107
+ R+D EE+ L+ + + R+E+ R+ E+ ++
Sbjct: 1397 QQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLR 1456
Query: 108 KRKHARVKEKE---REHERRKRHREEQDKARREWERQKRREMAREHSRRER 155
+ +H + +E+E +E E ++ HR+E+D+ E E+Q RR+ R+ RE+
Sbjct: 1457 QERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ-ERDRKFREQ 1506
Score = 45.1 bits (105), Expect = 2e-05
Identities = 40/155 (25%), Positives = 70/155 (45%), Gaps = 18/155 (11%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSP---YRREDSME 74
Q++ R +EE+ E + K + RD K E+ LR+ R E R +R E+ +
Sbjct: 1287 QQRDRHFPEEEQLEREEQKEAKRRDRKSQE-EKQLLREEREEKRRRQETDRKFREEEQLL 1345
Query: 75 DRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE----------HERR 124
EE + ++ +E H + K E+ + R +E+ER+ ER
Sbjct: 1346 QEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQERE 1405
Query: 125 KRHREEQDKARREWE----RQKRREMAREHSRRER 155
++ R+++D+ RE E RQ+R RE ++ R
Sbjct: 1406 QQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR 1440
Score = 45.1 bits (105), Expect = 2e-05
Identities = 35/159 (22%), Positives = 78/159 (49%), Gaps = 18/159 (11%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNS-----DDRDSKRDSLEEGELRDHRMEITIRNSPYRR 69
++ ++++ RK +EE+ +++R + +++ +R LE + ++ RR
Sbjct: 1683 QLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRR 1742
Query: 70 EDSMEDRGEEDDSLAIKPPQQMSRKEK-AHHRKDEKRKEKRKHARVKEKE-----REHER 123
++ EE+ + QQ+ R+E+ R++E+ +++R+ +++ +E RE E+
Sbjct: 1743 QERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQ 1802
Query: 124 RKRHREEQ-------DKARREWERQKRREMAREHSRRER 155
++ REEQ D R E Q + E + R+ER
Sbjct: 1803 LRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQER 1841
Score = 44.7 bits (104), Expect = 3e-05
Identities = 42/153 (27%), Positives = 75/153 (49%), Gaps = 16/153 (10%)
Query: 18 QEKKR----R--KEQEEKAEIKRLKNSDDRDSKRD------SLEEGELRDHRMEITIR-N 64
QEK+R R +E+EE KR + D D + D +E +RD+++ R N
Sbjct: 1188 QEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGREN 1247
Query: 65 SPYRR-EDS-MEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARV-KEKEREH 121
+R+ EDS + DR + D + QQ +E+ R ++ + + ++ +E+++E
Sbjct: 1248 EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEA 1307
Query: 122 ERRKRHREEQDKARREWERQKRREMAREHSRRE 154
+RR R +E+ + RE +KRR + RE
Sbjct: 1308 KRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340
Score = 44.7 bits (104), Expect = 3e-05
Identities = 37/149 (24%), Positives = 76/149 (51%), Gaps = 17/149 (11%)
Query: 18 QEKKRRKEQE------EKAEIKRLKNSDDRDSKRDSLEEGE-LRDHRMEITIRNSPYRRE 70
+E++RR+ Q+ E+ +++R + + + R S EE + LR+ R E RR+
Sbjct: 1279 REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREE------KRRRQ 1332
Query: 71 DSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHR-- 128
++ EE+ L + Q + R+E+ ++E+ + + + + E+E+ R++R R
Sbjct: 1333 ETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKF 1392
Query: 129 --EEQDKARREWERQKRREMAREHSRRER 155
EEQ +E E+Q R++ R+ E+
Sbjct: 1393 LKEEQQLRCQEREQQLRQDRDRKFREEEQ 1421
Score = 44.7 bits (104), Expect = 3e-05
Identities = 35/143 (24%), Positives = 66/143 (46%), Gaps = 14/143 (9%)
Query: 18 QEKKRRKEQEEK--AEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMED 75
++K RR+EQE K + ++L+ + + R + D ++ RE+
Sbjct: 1585 EQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLL-------QEREEQQLH 1637
Query: 76 RGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKE----REHERRKRHREEQ 131
R E D + PQ ++ + R D RK + + ++E E R ER ++ REE+
Sbjct: 1638 RQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEE 1697
Query: 132 DKARREWERQKRREMAREHSRRE 154
+ RR+ ER+++ + RR+
Sbjct: 1698 QQLRRQ-ERERKFLQEEQQLRRQ 1719
Score = 44.3 bits (103), Expect = 4e-05
Identities = 32/163 (19%), Positives = 79/163 (48%), Gaps = 22/163 (13%)
Query: 14 DEILQEKKRR---KEQEEKAEIKRLKNSDDRDSKRDS--------------LEEGELRDH 56
+E LQ +KR+ +++++++++K + ++ RD+ LE+ +LRD
Sbjct: 1202 EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDR 1261
Query: 57 RMEITIRN---SPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHAR 113
+ + +++ R+ E R + +Q+ R+E+ ++ +++ ++ K
Sbjct: 1262 QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLL 1321
Query: 114 VKEKEREHERRKRHRE--EQDKARREWERQKRREMAREHSRRE 154
+E+E + R++ R+ E+++ +E E Q R R+ RE
Sbjct: 1322 REEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE 1364
Score = 44.3 bits (103), Expect = 4e-05
Identities = 37/160 (23%), Positives = 78/160 (48%), Gaps = 12/160 (7%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITI 62
+E+ + + D +E++ R ++ E+ ++ + + +R L+E E + R E
Sbjct: 1489 EEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQE-EQQLRRQE--- 1544
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKE-----KAHHRKDEKRKEKRKHARVKEK 117
RR+D EE+ + QQ+SR+E + +K +++++RK +++
Sbjct: 1545 -RGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQ 1603
Query: 118 EREHERRKRHREEQDKARREWER--QKRREMAREHSRRER 155
R E +++ R+E+D+ RE E+ Q+R E R+R
Sbjct: 1604 LRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDR 1643
Score = 43.9 bits (102), Expect = 6e-05
Identities = 41/178 (23%), Positives = 78/178 (43%), Gaps = 24/178 (13%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSL--EEGELRDHRM 58
M DE+ + + ++ QE+ R+ ++E+ +R + R + EE +LR
Sbjct: 1598 MEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQER 1657
Query: 59 EITIRNS---PYRREDSMEDRGEED-------DSLAIKPPQQMSRKEKAHHRKDEKRKEK 108
E +R+ +R E+ + GEE D + QQ+ R+E+ E+++ +
Sbjct: 1658 EQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLR 1717
Query: 109 RKHARVKEKEREHERRKRHRE------------EQDKARREWERQKRREMAREHSRRE 154
R+ K +E E R++ +E E+++ R E E Q+ R R+ RE
Sbjct: 1718 RQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFRE 1775
Score = 43.1 bits (100), Expect = 9e-05
Identities = 34/142 (23%), Positives = 67/142 (47%), Gaps = 8/142 (5%)
Query: 18 QEKKRRKE------QEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRRED 71
+EK+RR+E +EE+A ++ + RD E + R ++ R P R +
Sbjct: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSAR-PPLREQR 794
Query: 72 SMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQ 131
+ R EE + + KE+ ++ E+ KE + +E+ + ER ++ +EE+
Sbjct: 795 ERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKE-LQFLEEEEQLQRRERAQQLQEEE 853
Query: 132 DKARREWERQKRREMAREHSRR 153
D + + ER++ +E R+ R
Sbjct: 854 DGLQEDQERRRSQEQRRDQKWR 875
Score = 43.1 bits (100), Expect = 9e-05
Identities = 34/139 (24%), Positives = 69/139 (49%), Gaps = 4/139 (2%)
Query: 19 EKKRRKEQEEKAEIKRLKNSDDR--DSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
+++ RK QEEK ++ + R ++ R EE +L R E +R R+ E+
Sbjct: 1308 KRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEEL 1367
Query: 77 GEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARR 136
++ +Q R+++ + ++ ++ R R ++ ++ +R+ R EEQ +R+
Sbjct: 1368 RHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFR-EEEQQLSRQ 1426
Query: 137 EWERQKRREMAREHSRRER 155
E +R K RE ++ R+ER
Sbjct: 1427 ERDR-KFREEEQQVRRQER 1444
Score = 41.6 bits (96), Expect = 3e-04
Identities = 40/149 (26%), Positives = 76/149 (51%), Gaps = 23/149 (15%)
Query: 18 QEKKRR-KEQEEKAEIKRLKNSDDRDSKRDSL------EEGELRDHRMEITIR-NSPYRR 69
QE++R+ +E+EE KR + D D + D +E +RD+++ R N +R+
Sbjct: 1193 QERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1252
Query: 70 -EDS-MEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRH 127
EDS + DR + D Q + +++ R+ E+R+ +++ E+E+
Sbjct: 1253 LEDSQLRDRQSQQDL------QHLLGEQQERDREQERRRWQQRDRHFPEEEQ------LE 1300
Query: 128 REEQDKA-RREWERQKRREMAREHSRRER 155
REEQ +A RR+ + Q+ +++ RE +R
Sbjct: 1301 REEQKEAKRRDRKSQEEKQLLREEREEKR 1329
Score = 38.1 bits (87), Expect = 0.003
Identities = 25/134 (18%), Positives = 68/134 (50%), Gaps = 10/134 (7%)
Query: 9 KVKTLDEILQEKKRRKEQEEKAEIK-----RLKNSDDRDSKRDSLEEGELR--DHRMEIT 61
K + +++ QE++ ++ + ++++ K +L+ + R +G+ R + ++++
Sbjct: 1772 KFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLE 1831
Query: 62 IRNSPYRREDSMEDRGEEDDSLAIKP---PQQMSRKEKAHHRKDEKRKEKRKHARVKEKE 118
+ R+E + R EE + K Q++ ++E+ R++ +RK + +H R ++KE
Sbjct: 1832 EQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKE 1891
Query: 119 REHERRKRHREEQD 132
+ R+ + Q+
Sbjct: 1892 EQRHRQVGEIKSQE 1905
Score = 32.0 bits (71), Expect = 0.22
Identities = 15/58 (25%), Positives = 33/58 (56%), Gaps = 3/58 (5%)
Query: 101 KDEKRKEKRKHARVKEKEREHE---RRKRHREEQDKARREWERQKRREMAREHSRRER 155
+D +++E ++ ++++ E E RR++ R+EQ++ E E Q ++ E R+R
Sbjct: 111 QDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQR 168
Score = 26.6 bits (57), Expect = 9.2
Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 3/50 (6%)
Query: 106 KEKRKHARVKE---KEREHERRKRHREEQDKARREWERQKRREMAREHSR 152
+EKR KE ++R E +R E +D+ E Q+RR+ +E R
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQER 146
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 60.1 bits (144), Expect = 8e-10
Identities = 32/138 (23%), Positives = 67/138 (48%), Gaps = 23/138 (16%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
++KK++KE EE E + + ++++ KR +E E R
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKR-----------------------KEKRKEKRK 38
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARRE 137
E++ K ++ KE+ ++ KRK+K++ +E+E E E K E+++ RR+
Sbjct: 39 EKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRK 98
Query: 138 WERQKRREMAREHSRRER 155
++++RR+ E +++R
Sbjct: 99 KKKKRRRKEEEEEKKKKR 116
Score = 57.8 bits (138), Expect = 4e-09
Identities = 30/137 (21%), Positives = 74/137 (54%), Gaps = 14/137 (10%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
++KK++K++ E+ E + +++ + +EG+ ++ R E R+E + +
Sbjct: 1 KKKKKKKKETEETE-------ETEETEEEEEKEGKRKEKRKE-------KRKEKEKKKKT 46
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARRE 137
+E + K ++ RK K +K+E+ +E+ + +EKE E + R R+++ K RR+
Sbjct: 47 KETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK 106
Query: 138 WERQKRREMAREHSRRE 154
E +++++ R ++++
Sbjct: 107 EEEEEKKKKRRRKTKKK 123
Score = 52.0 bits (123), Expect = 2e-07
Identities = 33/123 (26%), Positives = 61/123 (49%), Gaps = 17/123 (13%)
Query: 11 KTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRRE 70
+T +E +E KR+++++EK + K K KR EE E + R + + E
Sbjct: 18 ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR-----KRKKKKEE 72
Query: 71 DSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREE 130
+ E+ EE++ +EK K+E R+ K+K R +++E E +++KR R+
Sbjct: 73 EEREEEEEEEE------------EEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120
Query: 131 QDK 133
+ K
Sbjct: 121 KKK 123
Score = 45.4 bits (106), Expect = 2e-05
Identities = 29/123 (23%), Positives = 57/123 (46%), Gaps = 2/123 (1%)
Query: 5 KDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSK--RDSLEEGELRDHRMEITI 62
K K K E +E + +E+EEK ++ K + R K + +E E R + E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHE 122
+ R++ E+ EE++ + ++ ++E +K +KR+ K + K+K R
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120
Query: 123 RRK 125
++K
Sbjct: 121 KKK 123
Score = 40.8 bits (94), Expect = 5e-04
Identities = 20/64 (31%), Positives = 39/64 (60%), Gaps = 1/64 (1%)
Query: 93 RKEKAHHRKDEKRKEKRKHARVKEKEREH-ERRKRHREEQDKARREWERQKRREMAREHS 151
+K+K ++ E+ +E + +EKE + E+RK R+E++K ++ E +KR+E E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 152 RRER 155
+R+R
Sbjct: 61 KRKR 64
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 59.7 bits (143), Expect = 1e-09
Identities = 41/145 (28%), Positives = 69/145 (47%), Gaps = 7/145 (4%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSME 74
E +E+ R++E+E + E + DR +RD + E R + R RE E
Sbjct: 16 ETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERE 75
Query: 75 DRGEEDDSLAIKPPQQMSR---KEKAHHRK---DEKRKEKRKHARVKEKEREHER-RKRH 127
+ + + +Q R K++ RK D R+ RK R ++K+ E ER R+R
Sbjct: 76 TERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERE 135
Query: 128 REEQDKARREWERQKRREMAREHSR 152
R+ Q + R+ +R+++RE RE R
Sbjct: 136 RQRQRERERQRQRERKRETDRERQR 160
Score = 55.5 bits (132), Expect = 2e-08
Identities = 33/144 (22%), Positives = 64/144 (44%), Gaps = 6/144 (4%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
Q + R+ + K + +RD +R E E R R +R+ E
Sbjct: 39 QRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDK 98
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKR--HREEQDKAR 135
+ D + + R K +D++ + +R R ++++RE ER+++ + E D+ R
Sbjct: 99 DRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRER 158
Query: 136 REW----ERQKRREMAREHSRRER 155
+ W ER+K R+ R+ R+E+
Sbjct: 159 QRWAEREERKKERKKERKKERKEK 182
Score = 54.7 bits (130), Expect = 3e-08
Identities = 39/146 (26%), Positives = 74/146 (50%), Gaps = 17/146 (11%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
++++R++E + E +R + DR +R++ E E R HR + +R D DR
Sbjct: 3 RQRERKRETDRGKETERER---DRQRERENQTERENR-HR-----QRDRHRERDRQTDRE 53
Query: 78 EEDDSLAIKPPQQMSRKE-----KAHHRKDEKRKEKRKHARVKEKEREHERRK---RHRE 129
+E + + Q+ +E + + +R+ KR+ R ++K+R+ ER++ R+RE
Sbjct: 54 KERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRE 113
Query: 130 EQDKARREWERQKRREMAREHSRRER 155
K RE ++Q RE RE R+ +
Sbjct: 114 RNRKGGRERDKQTERERDRERERQRQ 139
Score = 50.1 bits (118), Expect = 8e-07
Identities = 34/147 (23%), Positives = 72/147 (48%), Gaps = 9/147 (6%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSM 73
D +K R+ Q+E+ ++ + +R+++R + + R R+ RE
Sbjct: 47 DRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKR 106
Query: 74 E-DRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEK-----RKHARVKEKEREHERRKRH 127
E DR E + + + + +E+ R+ ++++E+ R+ R ++ER+ R
Sbjct: 107 ETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQ---RWAE 163
Query: 128 REEQDKARREWERQKRREMAREHSRRE 154
REE+ K R++ +++R+E +E RRE
Sbjct: 164 REERKKERKKERKKERKEKKKEEKRRE 190
Score = 47.8 bits (112), Expect = 4e-06
Identities = 32/136 (23%), Positives = 73/136 (53%), Gaps = 13/136 (9%)
Query: 11 KTLDEILQEKKRRKEQEEKAEIKRLKNSD-DRDSKRDSLEEGELRDHRMEITIRNSPYRR 69
+T E ++++R++++E K + R ++ D DR+ KR++ D E + R
Sbjct: 71 ETERETERQRERQRQRERKRQTDRERDKDRDRERKRET-------DRNRERNRKGGRERD 123
Query: 70 EDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHER-RKRHR 128
+ + +R E + + Q+ +++ RK E +E+++ A +E+++E ++ RK+ R
Sbjct: 124 KQTERERDRERE----RQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER 179
Query: 129 EEQDKARREWERQKRR 144
+E+ K + E +KR+
Sbjct: 180 KEKKKEEKRREDKKRK 195
Score = 40.8 bits (94), Expect = 5e-04
Identities = 21/68 (30%), Positives = 39/68 (57%), Gaps = 4/68 (5%)
Query: 91 MSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKAR---REWERQKRREMA 147
M R+ + D ++ +R+ R +E+E + ER RHR ++D+ R R+ +R+K RE
Sbjct: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHR-QRDRHRERDRQTDREKERERQ 59
Query: 148 REHSRRER 155
+E R+ +
Sbjct: 60 KERDRQRQ 67
Score = 40.8 bits (94), Expect = 5e-04
Identities = 25/93 (26%), Positives = 46/93 (49%), Gaps = 10/93 (10%)
Query: 70 EDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHA-------RVKEKEREHE 122
E E + E D + + R+ + ++ + +++ +H R KE+ER+ E
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 123 R---RKRHREEQDKARREWERQKRREMAREHSR 152
R R+R RE + + R+ ERQ++RE R+ R
Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDR 94
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 59.3 bits (142), Expect = 1e-09
Identities = 38/153 (24%), Positives = 79/153 (51%), Gaps = 12/153 (7%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPY-----R 68
DEI +K +E +E+AE +R + + + + ++ ++ D R I R
Sbjct: 249 DEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERER 308
Query: 69 REDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHA-----RVKEKERE--H 121
RE +R E++ A + Q++ +EK + ++ KE+ K A R+KE+E+
Sbjct: 309 REAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE 368
Query: 122 ERRKRHREEQDKARREWERQKRREMAREHSRRE 154
ER++ EE++KA+ E +++ ++ ++H+ +E
Sbjct: 369 ERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQE 401
Score = 50.8 bits (120), Expect = 5e-07
Identities = 35/153 (22%), Positives = 70/153 (45%), Gaps = 7/153 (4%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEG--ELRDHRMEIT 61
+K+ W+ + + KK KE+EE+ E K + S + +EE E ++ + ++
Sbjct: 173 QKNDWR-----DAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMS 227
Query: 62 IRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREH 121
++N E+ ++ E S I ++M ++K + R E + R+K ++ +
Sbjct: 228 LKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKK 287
Query: 122 ERRKRHREEQDKARREWERQKRREMAREHSRRE 154
+R R E ++ ER++R RE R E
Sbjct: 288 IADERARIEAEEKAAAQERERREAEERERMREE 320
Score = 44.7 bits (104), Expect = 3e-05
Identities = 29/144 (20%), Positives = 68/144 (47%), Gaps = 9/144 (6%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+ ++ R E+EEKA+++ K + + K+ +++E +++ ++E I + + ED+
Sbjct: 369 ERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKL 428
Query: 78 E--------EDDSLAIKPPQQMSRKEKAHHRKDEKRKEK-RKHARVKEKEREHERRKRHR 128
+ E+ ++ ++ +++K +K+E + EK +K KE+ + RK+
Sbjct: 429 QTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGF 488
Query: 129 EEQDKARREWERQKRREMAREHSR 152
E E+ K + SR
Sbjct: 489 TEVKSQNGEFMTHKLKHTENTFSR 512
Score = 43.1 bits (100), Expect = 9e-05
Identities = 41/149 (27%), Positives = 73/149 (48%), Gaps = 21/149 (14%)
Query: 18 QEKKRRKEQEEKA-EIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
+E K+ +E+E+ + EI + ++ D +R E L E R + +D+
Sbjct: 236 EEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERE---------RIKAEQDK 286
Query: 77 GEEDDSLAIKPPQQMSRKEKAHHRKDEKR---KEKRKHA-----RVKEKE-REHERRKRH 127
D+ I+ ++ + +E+ R+ E+R +E+ K A R+KE+E R E R+R
Sbjct: 287 KIADERARIEAEEKAAAQER-ERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRI 345
Query: 128 REEQDKARREWERQKRRE-MAREHSRRER 155
+EE+ +A E +R K E A E +R R
Sbjct: 346 KEEEKRAAEERQRIKEEEKRAAEERQRAR 374
Score = 43.1 bits (100), Expect = 9e-05
Identities = 40/172 (23%), Positives = 76/172 (44%), Gaps = 20/172 (11%)
Query: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSL-----------EE 50
G+EK + KV+ E LQE K ++EE + K K+ + ++ + + +
Sbjct: 437 GEEKGT-KVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQN 495
Query: 51 GELRDHRMEIT----IRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRK 106
GE H+++ T R D+ E G + + R+ + + EK K
Sbjct: 496 GEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLK 555
Query: 107 EKRKHARVK----EKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
+K++ A ++ +K+RE R+ EEQ + + E +R+ R E + + E
Sbjct: 556 QKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEE 607
Score = 42.4 bits (98), Expect = 2e-04
Identities = 41/153 (26%), Positives = 69/153 (45%), Gaps = 18/153 (11%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKN---SDDRDSKRDSLEEG--ELRDHRMEITIRNSPYRR 69
E++ E+K + QEE + LKN S + + + E+G E+ H + R
Sbjct: 209 EVMVEEKTTESQEETV-VMSLKNGQISSEEPKQEEEREQGSDEISHHEK---MEEEDKER 264
Query: 70 EDSMEDRGEEDDSLAIKPPQQMS-RKEKAHHRKDEK-------RKEKRKHARVKEKE-RE 120
++ R E ++ IK Q E+A +EK R+E + R++E+E R
Sbjct: 265 AEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRA 324
Query: 121 HERRKRHREEQDKARREWERQKRREMAREHSRR 153
E R+R +EE+ +A E +R K E R+
Sbjct: 325 AEERQRIKEEEKRAAEERQRIKEEEKRAAEERQ 357
Score = 38.1 bits (87), Expect = 0.003
Identities = 31/143 (21%), Positives = 67/143 (46%), Gaps = 14/143 (9%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSM 73
D+ + +++ R E EEKA + + + + +R EE + R I +R
Sbjct: 285 DKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRI---KEEEKRAAEE 341
Query: 74 EDRGEEDDSLAIKPPQQMSRKEK--------AHHRKDEKRK--EKRKHARVKEKEREHER 123
R +E++ A + Q++ +EK A ++EK K E++++ +++EK+ +
Sbjct: 342 RQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQE 401
Query: 124 RKRHREE-QDKARREWERQKRRE 145
K E+ + K +W +K+ +
Sbjct: 402 TKIKGEKVEQKIEGKWVNEKKAQ 424
Score = 37.4 bits (85), Expect = 0.005
Identities = 27/136 (19%), Positives = 62/136 (45%), Gaps = 19/136 (13%)
Query: 9 KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYR 68
+++ ++ +++ R+E EE+ ++ + + +R EE + R I
Sbjct: 294 RIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRI-------- 345
Query: 69 REDSMEDRGEEDDSLAIKPPQQMSRKEK-AHHRKDEKRKEKRKHARVKEKEREHE-RRKR 126
+E++ A + Q++ +EK A + R E+ + A+V+E++R + K+
Sbjct: 346 ---------KEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKK 396
Query: 127 HREEQDKARREWERQK 142
H ++ K + E QK
Sbjct: 397 HAMQETKIKGEKVEQK 412
Score = 36.2 bits (82), Expect = 0.012
Identities = 33/126 (26%), Positives = 57/126 (45%), Gaps = 9/126 (7%)
Query: 31 EIKRLKNSDDRDSKRDSLEEGELRDH-RMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQ 89
++K +N+ R R S++ E ++E R RR E EE + L K +
Sbjct: 502 KLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRG-ETESEEFEKLKQKQQE 560
Query: 90 QMSRKEKAHHRKDEKRK------EKRKHARVKEKEREHERRKRHREEQDKARREWERQKR 143
E+ +++E+RK ++RK K RE E KR +E+ + RR +KR
Sbjct: 561 AALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEE-KRRLKEEIERRRAEAAEKR 619
Query: 144 REMARE 149
++M +
Sbjct: 620 QKMPED 625
Score = 33.1 bits (74), Expect = 0.098
Identities = 34/166 (20%), Positives = 73/166 (43%), Gaps = 17/166 (10%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIR 63
E++ + + + + +E+KR E E+ IK + + +R EE + R I
Sbjct: 305 ERERREAEERERMREEEKRAAE--ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIK-E 361
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHR------KDEKRKEKRKHARVKEK 117
E+ R EE++ ++ ++ + E+ H K EK ++K + V EK
Sbjct: 362 EEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEK 421
Query: 118 EREHER-----RKRHREEQD---KARREWERQKRREMAREHSRRER 155
+ + ++ K+ EE+ +A+RE ++ + +E + E+
Sbjct: 422 KAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEK 467
Score = 32.0 bits (71), Expect = 0.22
Identities = 17/55 (30%), Positives = 32/55 (58%), Gaps = 3/55 (5%)
Query: 100 RKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
R+ E R++KR+ R+ E E +R+ +++++A RE R+ R+E R+ E
Sbjct: 6 RRRELRRQKREEMRL---EAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEE 57
Score = 30.8 bits (68), Expect = 0.49
Identities = 27/116 (23%), Positives = 52/116 (44%), Gaps = 10/116 (8%)
Query: 27 EEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIK 86
+E A ++RL ++R KR L+E R + TI ++ S+ R ++D+ +
Sbjct: 92 DEAAFLERLARREERRQKR--LQEALERQKEFDPTITDASL----SLPSRRMQNDTAENE 145
Query: 87 PPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARREWERQK 142
++ + E R + + E + K R+ E K+ +DK + E E +K
Sbjct: 146 TTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKK----EDKEKEEEEEEK 197
Score = 29.3 bits (64), Expect = 1.4
Identities = 33/133 (24%), Positives = 53/133 (39%), Gaps = 18/133 (13%)
Query: 20 KKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEE 79
++RR+ + +K E RL+ + D EE R+ R R R++ E G+
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRA--RQERLRQKQEEESLGQV 62
Query: 80 DDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARREWE 139
D + + + DE+ K + +V E + E R ARRE
Sbjct: 63 TDQVEVNAQNSVP---------DEEAKTTTTNTQV---EGDDEAAFLER----LARREER 106
Query: 140 RQKRREMAREHSR 152
RQKR + A E +
Sbjct: 107 RQKRLQEALERQK 119
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 57.0 bits (136), Expect = 6e-09
Identities = 30/152 (19%), Positives = 73/152 (48%), Gaps = 4/152 (2%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIR 63
E+D + + D ++++ R+ ++++ + + +RD +R+ +E E R R
Sbjct: 136 ERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRD----R 191
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHER 123
+E + E D + +Q + D +R+ +R R KE++RE +R
Sbjct: 192 QRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDR 251
Query: 124 RKRHREEQDKARREWERQKRREMAREHSRRER 155
++ ++E+ K R++ ++K++E R ++ +
Sbjct: 252 KEERKKERKKERKKERKEKKKEEKRREDKKRK 283
Score = 56.2 bits (134), Expect = 1e-08
Identities = 32/124 (25%), Positives = 64/124 (51%), Gaps = 7/124 (5%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSME 74
E +E+ R +E++++ E +R DRD +RD+ +E E + R R + R+ +
Sbjct: 168 ETERERDREREKQKERETER-----DRDRQRDTEKERERQTDRERDRQRKTQTERQRETD 222
Query: 75 DRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKA 134
GE + + +Q R ++ RKE+RK R KE+++E + +K+ + ++
Sbjct: 223 REGERETDR--RRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDK 280
Query: 135 RREW 138
+R+W
Sbjct: 281 KRKW 284
Score = 53.1 bits (126), Expect = 9e-08
Identities = 40/157 (25%), Positives = 74/157 (47%), Gaps = 7/157 (4%)
Query: 4 EKDSWKVKTLDEILQEKKR-----RKEQEEKAEIKRLKNSD-DRDSKRDSLEEGELRDHR 57
E+D + KT E +++KR RKE+E R K ++ +RD +R+ + E R
Sbjct: 80 ERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDR 139
Query: 58 MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEK 117
R+ +E + + D + ++ R+ + ++ +R R+ KE+
Sbjct: 140 GRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKER 199
Query: 118 EREHER-RKRHREEQDKARREWERQKRREMAREHSRR 153
ER+ +R R R R+ Q + +RE +R+ RE R R+
Sbjct: 200 ERQTDRERDRQRKTQTERQRETDREGERETDRRRERQ 236
Score = 52.4 bits (124), Expect = 2e-07
Identities = 35/146 (23%), Positives = 69/146 (47%), Gaps = 8/146 (5%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSD-DRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDR 76
+E++++K +E + + R + D DR+ +R+ E + R T R RE E
Sbjct: 125 REREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERE 184
Query: 77 GEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKAR- 135
E D ++ R+ + K + +R+ +E ERE +RR+ + ++D+ +
Sbjct: 185 TERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKE 244
Query: 136 ------REWERQKRREMAREHSRRER 155
R+ ER+K R+ R+ R+E+
Sbjct: 245 RDRERDRKEERKKERKKERKKERKEK 270
Score = 49.7 bits (117), Expect = 1e-06
Identities = 35/144 (24%), Positives = 71/144 (49%), Gaps = 10/144 (6%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSM 73
D+ +E+ R +E+ EK + K DR+ +R E RD + I R +
Sbjct: 75 DDRQRERDRVREKTEKERDRDRKR--DRERRRKEKETNRNRDREKQTEIE----RDRERE 128
Query: 74 EDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARV-KEKEREHERRKRHREEQD 132
+ +G E + + ++ +EK R+ EK ++ ++ +E++RE E++K E+D
Sbjct: 129 KQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERD 188
Query: 133 KARR---EWERQKRREMAREHSRR 153
+ R+ E ER+++ + R+ R+
Sbjct: 189 RDRQRDTEKERERQTDRERDRQRK 212
Score = 48.5 bits (114), Expect = 2e-06
Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 3/120 (2%)
Query: 37 NSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEK 96
+ DDR +RD + E ++ + R+E + + I+ ++ +++
Sbjct: 73 DGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKG 132
Query: 97 AHHRKDEKRKEKRKHARVKEKEREHERRK---RHREEQDKARREWERQKRREMAREHSRR 153
+D R+ +R R KE+ER+ E+ + R E + + RE E+QK RE R+ R+
Sbjct: 133 RERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQ 192
Score = 48.1 bits (113), Expect = 3e-06
Identities = 30/138 (21%), Positives = 66/138 (47%), Gaps = 6/138 (4%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+E R +++E++ EI+R + + + + + G R+ + R R+ + G
Sbjct: 107 KETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRD---REKERERQTEKDRDG 163
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHER-RKRHREEQDKARR 136
+ + + ++ ++++ +D R+ + R ++ +RE +R RK E Q + R
Sbjct: 164 QRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDR 223
Query: 137 EWERQ--KRREMAREHSR 152
E ER+ +RRE R+ R
Sbjct: 224 EGERETDRRRERQRDRDR 241
Score = 44.3 bits (103), Expect = 4e-05
Identities = 29/119 (24%), Positives = 61/119 (51%), Gaps = 9/119 (7%)
Query: 36 KNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKE 95
K++D D +R+ RD E T + R+ E R +E ++ + ++ + E
Sbjct: 70 KDADGDDRQRE-------RDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIE 122
Query: 96 KAHHRKDEKRKEK-RKHARVKEKEREHERRKRHREEQDK-ARREWERQKRREMAREHSR 152
+ R+ +K +E+ R R +E++R+ E+ + + E+D+ +RE E ++ R+ RE +
Sbjct: 123 RDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQK 181
Score = 39.3 bits (90), Expect = 0.001
Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 11/99 (11%)
Query: 68 RREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKE-------KRKHARVKEKERE 120
R D + ++ E++ K ++ RKEK +R ++ K+ +R+ + +E+ER+
Sbjct: 79 RERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERD 138
Query: 121 HER---RKRHREEQDKARREWERQKRREMAREHSR-RER 155
R R R RE++ + + E +R +RE E R RER
Sbjct: 139 RGRERERDRDREKERERQTEKDRDGQRETETERERDRER 177
Score = 33.5 bits (75), Expect = 0.075
Identities = 21/62 (33%), Positives = 37/62 (59%), Gaps = 5/62 (8%)
Query: 99 HRKDEKRKEKRKHARVKEK-EREHER-RKRHREEQDKAR---REWERQKRREMAREHSRR 153
H+ + +R+ RV+EK E+E +R RKR RE + K + R +R+K+ E+ R+ R
Sbjct: 69 HKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRERE 128
Query: 154 ER 155
++
Sbjct: 129 KQ 130
Score = 26.9 bits (58), Expect = 7.0
Identities = 12/49 (24%), Positives = 27/49 (55%)
Query: 107 EKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 155
+ K A +++RE +R + E++ R+ +R++RR+ + R+R
Sbjct: 67 QAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDR 115
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 57.0 bits (136), Expect = 6e-09
Identities = 36/150 (24%), Positives = 80/150 (53%), Gaps = 10/150 (6%)
Query: 13 LDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDS 72
L ++LQ ++R ++ +E+ + + + D K + +E L + + + + + ++ +
Sbjct: 578 LRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAK---KKAAAKKMEE 634
Query: 73 MEDRGEEDDSLAIKPPQQMSRKEKAHH-----RKDEKRKEKRKHARVKE--KEREHERRK 125
+E R ++++ Q +E+ H +K+E+++ RK A K ++RE ERR+
Sbjct: 635 VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE 694
Query: 126 RHREEQDKARREWERQKRREMAREHSRRER 155
+ R EQ++ +E Q+RRE R+ + +ER
Sbjct: 695 QERREQERREQERREQERREQERQLAEQER 724
Score = 50.4 bits (119), Expect = 6e-07
Identities = 45/161 (27%), Positives = 83/161 (51%), Gaps = 24/161 (14%)
Query: 13 LDEILQEKKRRKEQE--------EKAEIKRL-KNSDDRDSKRDSLEEGELRDHRMEITIR 63
++++ +EKK++ EQ+ EKA+ +RL + + + +EE E R + E R
Sbjct: 588 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEAR-RKQEEEAR 646
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRK---DEKRKEKRKHARVKEKERE 120
+ +++ E R +E L K ++ R KA K +++ +E+R+ R +++ RE
Sbjct: 647 RLRWLQQEEEERRHQE--LLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 704
Query: 121 HERRKRHREEQDKA------RREWERQKRREMAREHSRRER 155
ERR++ R EQ++ RRE Q+R + RE RE+
Sbjct: 705 QERREQERREQERQLAEQERRRE---QERLQAERELQEREK 742
Score = 48.1 bits (113), Expect = 3e-06
Identities = 33/159 (20%), Positives = 79/159 (49%), Gaps = 16/159 (10%)
Query: 1 MGDEKDSWKV--KTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRM 58
+ +EK K K ++E+ + RRK++EE ++ L+ ++ ++ L++ + +
Sbjct: 618 LAEEKAKKKAAAKKMEEV---EARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQER 674
Query: 59 EITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKE 118
+ E ++R E+ ++ ++ + R++++R+E+ + +E+
Sbjct: 675 LRKAAEAKRLAEQREQERREQ---------ERREQERREQERREQERREQERQLAEQERR 725
Query: 119 REHERRKRHRE--EQDKARREWERQKRREMAREHSRRER 155
RE ER + RE E++KA R + Q +RE+ + + E+
Sbjct: 726 REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQ 764
Score = 46.6 bits (109), Expect = 9e-06
Identities = 34/135 (25%), Positives = 71/135 (52%), Gaps = 21/135 (15%)
Query: 15 EILQEKKRRKEQE--EKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDS 72
E+LQ+KK +++ + AE KRL +++ + E E R+ RRE
Sbjct: 662 ELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQE----------RRE-- 709
Query: 73 MEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKE--REHERRKRHREE 130
++R E++ LA +Q R+E+ + + + +E+ K R+++++ RE E +K+ E+
Sbjct: 710 -QERREQERQLA----EQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQ 764
Query: 131 QDKARREWERQKRRE 145
Q A R+ + ++ ++
Sbjct: 765 QRLAERQLQEEQEKK 779
Score = 46.2 bits (108), Expect = 1e-05
Identities = 38/144 (26%), Positives = 68/144 (47%), Gaps = 11/144 (7%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+E++R + K E ++L+ + KR LEE +L+ E +R RE + +
Sbjct: 537 KERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLK---REERLRKVLQARERVEQMKE 593
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHA-------RVKEKEREHERRKRHREE 130
E+ + K Q + EKA + + K K+K A + K+ E RR R ++
Sbjct: 594 EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 653
Query: 131 QDKARREWE-RQKRREMAREHSRR 153
+++ RR E QK++E +E R+
Sbjct: 654 EEEERRHQELLQKKKEEEQERLRK 677
Score = 29.6 bits (65), Expect = 1.1
Identities = 19/90 (21%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
Query: 68 RREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRK---HARVKEKEREHERR 124
RR+ ED+ + + +K +++ + +A R E+ KE++K + + + + E+
Sbjct: 555 RRQKVEEDKRRRLEEVKLKREERLRKVLQARERV-EQMKEEKKKQIEQKFAQIDEKTEKA 613
Query: 125 KRHREEQDKARREWERQKRREMAREHSRRE 154
K R ++KA+++ +K E+ + E
Sbjct: 614 KEERLAEEKAKKKAAAKKMEEVEARRKQEE 643
Score = 28.1 bits (61), Expect = 3.2
Identities = 16/43 (37%), Positives = 27/43 (62%), Gaps = 3/43 (6%)
Query: 103 EKRKEKRKHARVKEKEREHERRKRHREEQDKARREWERQKRRE 145
EK +++ ++ R KE E E+ +R + E+DK RR E + +RE
Sbjct: 536 EKERQRLENLRRKE---EAEQLRRQKVEEDKRRRLEEVKLKRE 575
Score = 27.7 bits (60), Expect = 4.1
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 1/40 (2%)
Query: 116 EKEREHERRKRHREEQDKARREW-ERQKRREMAREHSRRE 154
EKER+ R +EE ++ RR+ E KRR + +RE
Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE 575
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 57.0 bits (136), Expect = 6e-09
Identities = 36/150 (24%), Positives = 80/150 (53%), Gaps = 10/150 (6%)
Query: 13 LDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDS 72
L ++LQ ++R ++ +E+ + + + D K + +E L + + + + + ++ +
Sbjct: 574 LRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAK---KKAAAKKMEE 630
Query: 73 MEDRGEEDDSLAIKPPQQMSRKEKAHH-----RKDEKRKEKRKHARVKE--KEREHERRK 125
+E R ++++ Q +E+ H +K+E+++ RK A K ++RE ERR+
Sbjct: 631 VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE 690
Query: 126 RHREEQDKARREWERQKRREMAREHSRRER 155
+ R EQ++ +E Q+RRE R+ + +ER
Sbjct: 691 QERREQERREQERREQERREQERQLAEQER 720
Score = 50.4 bits (119), Expect = 6e-07
Identities = 45/161 (27%), Positives = 83/161 (51%), Gaps = 24/161 (14%)
Query: 13 LDEILQEKKRRKEQE--------EKAEIKRL-KNSDDRDSKRDSLEEGELRDHRMEITIR 63
++++ +EKK++ EQ+ EKA+ +RL + + + +EE E R + E R
Sbjct: 584 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEAR-RKQEEEAR 642
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRK---DEKRKEKRKHARVKEKERE 120
+ +++ E R +E L K ++ R KA K +++ +E+R+ R +++ RE
Sbjct: 643 RLRWLQQEEEERRHQE--LLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
Query: 121 HERRKRHREEQDKA------RREWERQKRREMAREHSRRER 155
ERR++ R EQ++ RRE Q+R + RE RE+
Sbjct: 701 QERREQERREQERQLAEQERRRE---QERLQAERELQEREK 738
Score = 48.1 bits (113), Expect = 3e-06
Identities = 33/159 (20%), Positives = 79/159 (49%), Gaps = 16/159 (10%)
Query: 1 MGDEKDSWKV--KTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRM 58
+ +EK K K ++E+ + RRK++EE ++ L+ ++ ++ L++ + +
Sbjct: 614 LAEEKAKKKAAAKKMEEV---EARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQER 670
Query: 59 EITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKE 118
+ E ++R E+ ++ ++ + R++++R+E+ + +E+
Sbjct: 671 LRKAAEAKRLAEQREQERREQ---------ERREQERREQERREQERREQERQLAEQERR 721
Query: 119 REHERRKRHRE--EQDKARREWERQKRREMAREHSRRER 155
RE ER + RE E++KA R + Q +RE+ + + E+
Sbjct: 722 REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQ 760
Score = 46.6 bits (109), Expect = 9e-06
Identities = 39/149 (26%), Positives = 70/149 (46%), Gaps = 11/149 (7%)
Query: 13 LDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDS 72
+D +E++R + K E ++L+ + KR LEE +L+ E +R RE
Sbjct: 528 MDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLK---REERLRKVLQARERV 584
Query: 73 MEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHA-------RVKEKEREHERRK 125
+ + E+ + K Q + EKA + + K K+K A + K+ E RR
Sbjct: 585 EQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 644
Query: 126 RHREEQDKARREWE-RQKRREMAREHSRR 153
R +++++ RR E QK++E +E R+
Sbjct: 645 RWLQQEEEERRHQELLQKKKEEEQERLRK 673
Score = 46.6 bits (109), Expect = 9e-06
Identities = 34/135 (25%), Positives = 71/135 (52%), Gaps = 21/135 (15%)
Query: 15 EILQEKKRRKEQE--EKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDS 72
E+LQ+KK +++ + AE KRL +++ + E E R+ RRE
Sbjct: 658 ELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQE----------RRE-- 705
Query: 73 MEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKE--REHERRKRHREE 130
++R E++ LA +Q R+E+ + + + +E+ K R+++++ RE E +K+ E+
Sbjct: 706 -QERREQERQLA----EQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQ 760
Query: 131 QDKARREWERQKRRE 145
Q A R+ + ++ ++
Sbjct: 761 QRLAERQLQEEQEKK 775
Score = 31.2 bits (69), Expect = 0.37
Identities = 23/119 (19%), Positives = 56/119 (47%), Gaps = 11/119 (9%)
Query: 39 DDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAH 98
D ++ +R LE ++ ++ RR+ ED+ + + +K +++ + +A
Sbjct: 529 DPKEKERQRLENLRRKEEAEQL-------RRQKVEEDKRRRLEEVKLKREERLRKVLQAR 581
Query: 99 HRKDEKRKEKRK---HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
R E+ KE++K + + + + E+ K R ++KA+++ +K E+ + E
Sbjct: 582 ERV-EQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
Score = 30.4 bits (67), Expect = 0.64
Identities = 21/102 (20%), Positives = 49/102 (48%), Gaps = 11/102 (10%)
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHH----------RKDEKRKEKRKHA 112
RN+P R + ++R + ++L K + R++K K E+R K A
Sbjct: 522 RNTPLRMDPKEKER-QRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQA 580
Query: 113 RVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
R + ++ + E++K+ ++ + + E+ K +A E ++++
Sbjct: 581 RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKK 622
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 56.2 bits (134), Expect = 1e-08
Identities = 41/160 (25%), Positives = 83/160 (51%), Gaps = 15/160 (9%)
Query: 9 KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRM---EITIRNS 65
+++ ++ L+E+K +EQEE+ + + K + + R+ E+ ++ R+ E +R
Sbjct: 329 ELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 388
Query: 66 PYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKR----------KHARVK 115
+ D E E+D+ L K ++M +EK + ++ R+EK+ + +++
Sbjct: 389 EQKMRDQEERMWEQDERLREKE-ERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQ 447
Query: 116 EKEREHERRKRHREEQDKARREWER-QKRREMAREHSRRE 154
E+ER ER K+ REE++ R + E+ QK+ E E +E
Sbjct: 448 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE 487
Score = 52.0 bits (123), Expect = 2e-07
Identities = 35/175 (20%), Positives = 84/175 (48%), Gaps = 23/175 (13%)
Query: 2 GDEKDSWKVKTL----DEILQEKKRRKEQEEKA---EIKRLKNSDDRDSKRDSLEEGELR 54
G EK W+ + + D++ +++++ ++QE+K E + K + +++ K EE
Sbjct: 528 GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE 587
Query: 55 DHRM----------EITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKD-- 102
+ RM E +R + ++ E E+++ + + + ++EK +++
Sbjct: 588 EERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKM 647
Query: 103 ----EKRKEKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRR 153
EK E+++ KEK EHE+ + + Q++ + WE++K + +E ++
Sbjct: 648 WEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702
Score = 48.5 bits (114), Expect = 2e-06
Identities = 35/142 (24%), Positives = 77/142 (54%), Gaps = 9/142 (6%)
Query: 17 LQEKKRRKEQEEKAEIKRLKNSDD---RDSKRDSLEEGELRDHRMEITIRNSPYRREDSM 73
LQE+ R+E+E + + K+++ ++ R +R +EG++R+ ++ R RE
Sbjct: 270 LQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMW-RQEKRLREQEK 328
Query: 74 EDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDK 133
E R +E + ++ +++ +E+ ++EK E+ + +++E+E + R++ EQ+K
Sbjct: 329 ELREQEKE---LREQKELREQEEQMQEQEEKMWEQEE--KMREQEEKMWRQEERLWEQEK 383
Query: 134 ARREWERQKRREMAREHSRRER 155
RE E++ R + R + ER
Sbjct: 384 QMREQEQKMRDQEERMWEQDER 405
Score = 48.5 bits (114), Expect = 2e-06
Identities = 37/168 (22%), Positives = 85/168 (50%), Gaps = 17/168 (10%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRL-----KNSDDRDSKRDSLEEGELRD 55
M D+++ + KT + QEKK ++E+ E +R+ K ++ + R+ E+ + ++
Sbjct: 560 MWDQEERMEKKTQE---QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 616
Query: 56 HRMEITIRNSPYRREDSMEDRGE---EDDSLAIKPPQQMSRKEKAHHRKD-----EKRKE 107
+M+ + +E+ M+++ E E + + ++M +++ +K+ EK +E
Sbjct: 617 EKMQEQ-EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE 675
Query: 108 KRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 155
+ K +EK E E+ ++ +EQ+K + E+ + E RE ++ R
Sbjct: 676 QEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMR 723
Score = 48.5 bits (114), Expect = 2e-06
Identities = 31/144 (21%), Positives = 77/144 (53%), Gaps = 13/144 (9%)
Query: 15 EILQEKKRRKEQEEK--AEIKRLKNSDDRDSK---------RDSLEEGELRDHRMEITIR 63
E +QE+++ +EQEEK + K K + +++ K +S+ E E + E +R
Sbjct: 671 EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMR 730
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEK--AHHRKDEKRKEKRKHARVKEKEREH 121
+ ++ E E+++ + + + ++EK R E++++ +H +++E+E+
Sbjct: 731 EQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIW 790
Query: 122 ERRKRHREEQDKARREWERQKRRE 145
E+ ++ R++++K R + E+ + +E
Sbjct: 791 EQEEKMRDQEEKMRGQEEKMRGQE 814
Score = 46.6 bits (109), Expect = 9e-06
Identities = 26/141 (18%), Positives = 66/141 (46%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSM 73
+E +QE++ + +++E+ ++ + +++ K EE + P ++E
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 668
Query: 74 EDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDK 133
E ++ + +++ +EK + E+ K+ +++E+E ER K+ REE++
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM 728
Query: 134 ARREWERQKRREMAREHSRRE 154
R + E+ + +E + E
Sbjct: 729 MREQEEKMQEQEEKMQEQEEE 749
Score = 46.2 bits (108), Expect = 1e-05
Identities = 28/137 (20%), Positives = 68/137 (49%), Gaps = 17/137 (12%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSL--EEGELRDHRMEITIRNSPYRREDSMED 75
QE+K R ++E + K++ + + D + +E ++RD ++ + +E+ ME
Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM------WDQEERMEK 569
Query: 76 RGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREE----- 130
+ +E + ++M +E+ R+ + R+E+ +EK +E E + + +EE
Sbjct: 570 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQ 629
Query: 131 ----QDKARREWERQKR 143
Q++ + WE++++
Sbjct: 630 EEKMQEQEEKMWEQEEK 646
Score = 45.8 bits (107), Expect = 1e-05
Identities = 35/160 (21%), Positives = 82/160 (51%), Gaps = 16/160 (10%)
Query: 9 KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYR 68
K + +E +QE++R +E+E+K + + +++ K EE E + P +
Sbjct: 438 KTRDQEEKMQEEERIREREKKMREEE-ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 496
Query: 69 RE-----DSMEDRGEE--DDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREH 121
+E + M+++ E+ + I+ ++M +EK R+++ R+++ + +EK R+
Sbjct: 497 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 556
Query: 122 ERRKRHREE------QDKARREWERQKRREMAREHSRRER 155
E++ +EE Q++ ++ W+++++ M E RER
Sbjct: 557 EQKMWDQEERMEKKTQEQEKKTWDQEEK--MREEERMRER 594
Score = 43.5 bits (101), Expect = 7e-05
Identities = 36/149 (24%), Positives = 77/149 (51%), Gaps = 16/149 (10%)
Query: 14 DEILQEKKRRKEQEEKA--EIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRRED 71
DE L+EK+ R ++EK +++++ R+ K+ +E + RD ++ RE
Sbjct: 403 DERLREKEERMREQEKMWEQVEKM-----REEKKMQEQEKKTRDQEEKMQEEERIREREK 457
Query: 72 SMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHRE-- 129
M EE++++ + ++M ++E+ ++EK ++++ KEK E E+ + E
Sbjct: 458 KMR---EEEETMR-EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 513
Query: 130 -EQDKARREWERQ--KRREMAREHSRRER 155
EQ++ R+ E + ++M R+ RE+
Sbjct: 514 WEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542
Score = 42.7 bits (99), Expect = 1e-04
Identities = 37/159 (23%), Positives = 78/159 (49%), Gaps = 18/159 (11%)
Query: 9 KVKTLDEILQEKKRRKEQEE---KAEIKRLKNSDDR----------DSKRDSL--EEGEL 53
++K + LQEK E E+ + +K LK +R ++ ++ + +E EL
Sbjct: 222 ELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEEL 281
Query: 54 RDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHAR 113
R+ +I + R+ E+R E + + ++M R+EK ++++ +E+ K R
Sbjct: 282 REQEKKIRKQEEKMWRQ---EERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELR 338
Query: 114 VKEKEREHERRKRHREEQDKARREWERQKRREMAREHSR 152
+++ RE E + + +EE+ + E R++ +M R+ R
Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 377
Score = 42.4 bits (98), Expect = 2e-04
Identities = 32/151 (21%), Positives = 82/151 (54%), Gaps = 19/151 (12%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEK---------AEIKRLKNSDDRDSKRDSLEEGELR 54
E+ W+ + + + +++K+ +EQE+K + +RL+ ++R +++ + E ++
Sbjct: 368 EEKMWRQE--ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE-QVE 424
Query: 55 DHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARV 114
R E ++ + D E EE+ I+ ++ R+E+ R+ E++ +K++
Sbjct: 425 KMREEKKMQEQEKKTRDQEEKMQEEE---RIREREKKMREEEETMREQEEKMQKQEENMW 481
Query: 115 KEKEREHERRKRHREEQDKARREWERQKRRE 145
+++E+E + ++R E+++K WE++K +E
Sbjct: 482 EQEEKEWQ-QQRLPEQKEKL---WEQEKMQE 508
Score = 42.0 bits (97), Expect = 2e-04
Identities = 26/143 (18%), Positives = 74/143 (51%), Gaps = 6/143 (4%)
Query: 18 QEKKRRKEQEEKAEIKRL-----KNSDDRDSKRDSLEEGELRDHRM-EITIRNSPYRRED 71
QEKK R ++E+ E +R+ K ++ ++ R+ E+ + ++ M E + +R
Sbjct: 435 QEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 494
Query: 72 SMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQ 131
+++ E + + + + ++EK +++ +EK+ + K +E+E + ++ + +
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 554
Query: 132 DKARREWERQKRREMAREHSRRE 154
D+ ++ W++++R E + ++
Sbjct: 555 DQEQKMWDQEERMEKKTQEQEKK 577
Score = 42.0 bits (97), Expect = 2e-04
Identities = 27/142 (19%), Positives = 66/142 (46%), Gaps = 5/142 (3%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
QE+K +++E+ E +RL ++ + + ++E E + E ++ +++
Sbjct: 643 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQ--DKAR 135
D + R++K ++ R+++ K +EK +E E +EE+ ++
Sbjct: 703 TWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEE 762
Query: 136 REWERQK---RREMAREHSRRE 154
+ WE+Q+ ++E EH + +
Sbjct: 763 KMWEQQRLPEQKEKLWEHEKMQ 784
Score = 39.3 bits (90), Expect = 0.001
Identities = 35/158 (22%), Positives = 80/158 (50%), Gaps = 13/158 (8%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
M +E+++ + + QE+ +++E++ + +RL ++ +++ ++E E + E
Sbjct: 459 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 518
Query: 61 TIRNSP--YRREDSM---EDRGEEDDSLAIKPPQQMSRKEKA---HHRKDEKRKEKRKHA 112
IR+ + +E M E E++D + + + +++K R ++K +E+ K
Sbjct: 519 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKT 578
Query: 113 -RVKEKERE----HERRKRHREEQDKARREWERQKRRE 145
+EK RE ER K+ REE++ R + E+ + +E
Sbjct: 579 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 616
Score = 38.9 bits (89), Expect = 0.002
Identities = 30/151 (19%), Positives = 75/151 (49%), Gaps = 12/151 (7%)
Query: 9 KVKTLDEILQEKKRRK-EQEEKAEIKRLKNSDDRDS---KRDSLEEGELRDHRMEITIRN 64
K++ +E +QE++ + EQEEK + + K + + + + + E + + E +
Sbjct: 611 KMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH 670
Query: 65 SPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKE---REH 121
+ ++ M+++ E+ I ++M +K + +K +++ R+ ++E+E RE
Sbjct: 671 EKMQEQEKMQEQEEK-----IWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREE 725
Query: 122 ERRKRHREEQDKARREWERQKRREMAREHSR 152
E R +EE+ + + E +++ EM + +
Sbjct: 726 EEMMREQEEKMQEQEEKMQEQEEEMWEQEEK 756
Score = 35.4 bits (80), Expect = 0.020
Identities = 33/147 (22%), Positives = 72/147 (48%), Gaps = 10/147 (6%)
Query: 4 EKDSW----KVKTLDEILQEKKRRKEQEEKA-EIKRLKNSDDRDSKRDSLEEGELRDHRM 58
E++ W K+ +E + E++R EQ+EK E ++++ + + + + + E +
Sbjct: 747 EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ 806
Query: 59 EITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKE 118
E +R + E +++ + + + ++EK + +EK +EK + +EK
Sbjct: 807 EEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQ-EEKMEEKMQGQ--EEKM 863
Query: 119 REHERRKRHREEQDKARREWERQKRRE 145
RE E + R +EE K R + E+ + +E
Sbjct: 864 REQEEKMRGQEE--KMREQEEKMRGQE 888
Score = 35.4 bits (80), Expect = 0.020
Identities = 26/144 (18%), Positives = 72/144 (50%), Gaps = 6/144 (4%)
Query: 14 DEILQEKKRRKEQEEKA-EIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDS 72
+E+ +++++ EQEEK E +RL ++ + + ++E E + E +R+ +
Sbjct: 748 EEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE-KIWEQEEKMRDQEEKMRGQ 806
Query: 73 MEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRK----HARVKEKEREHERRKRHR 128
E +++ + + + ++EK ++++ ++ K +++EK + E + R +
Sbjct: 807 EEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQ 866
Query: 129 EEQDKARREWERQKRREMAREHSR 152
EE+ + + E R++ +M + +
Sbjct: 867 EEKMRGQEEKMREQEEKMRGQEEK 890
Score = 35.0 bits (79), Expect = 0.026
Identities = 27/123 (21%), Positives = 62/123 (50%), Gaps = 14/123 (11%)
Query: 9 KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYR 68
K++ ++I +++++ ++QEEK + K + R E+ ++ +M +
Sbjct: 782 KMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM--------WG 833
Query: 69 REDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHR 128
+E+ M G+E+ Q+ +EK ++++ R+++ K +EK RE E + R +
Sbjct: 834 QEEKMW--GQEEKMWG----QEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQ 887
Query: 129 EEQ 131
EE+
Sbjct: 888 EEK 890
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 56.2 bits (134), Expect = 1e-08
Identities = 34/157 (21%), Positives = 81/157 (51%), Gaps = 7/157 (4%)
Query: 3 DEKDSW----KVKTLDEILQEKKRRKEQEEKA---EIKRLKNSDDRDSKRDSLEEGELRD 55
++++ W K++ +EI ++K++ EQEEK E K + + + + + E E +
Sbjct: 521 EQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKV 580
Query: 56 HRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVK 115
R E IR + + E E+++ + + ++EK ++++ ++++ K R +
Sbjct: 581 WRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQE 640
Query: 116 EKEREHERRKRHREEQDKARREWERQKRREMAREHSR 152
EK RE E++ R +EE+ + + E +++ +M + +
Sbjct: 641 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 677
Score = 53.9 bits (128), Expect = 5e-08
Identities = 38/151 (25%), Positives = 83/151 (54%), Gaps = 21/151 (13%)
Query: 9 KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYR 68
K++ L+E + E+++ +EQEEK + +++ +++ +E E + R E IR
Sbjct: 439 KIRELEEKMHEQEKIREQEEK------RQEEEKIREQEKRQEQEAKMWRQEEKIREQ--- 489
Query: 69 REDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHE----RR 124
E++ E + + +++ +EK R++EKR+E+ + R +EK RE E ++
Sbjct: 490 -----EEKIREQEEKMWRQEEKIHEQEKI--REEEKRQEQEEMWRQEEKIREQEEIWRQK 542
Query: 125 KRHREEQDKARREWERQKRREMAREHSRRER 155
++ E+++K R++ E+ R+E + H + E+
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQE-EKMHDQEEK 572
Score = 53.5 bits (127), Expect = 7e-08
Identities = 34/164 (20%), Positives = 87/164 (53%), Gaps = 14/164 (8%)
Query: 3 DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLE-----EGELRDHR 57
++++ W+ K ++I +++++ ++QEEK + K D + R+ E E ++R+
Sbjct: 534 EQEEIWRQK--EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQE 591
Query: 58 MEITIRNSPYRREDSM-----EDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHA 112
+I + R ++ M E GE+++ + + + ++EK ++++ R++++K
Sbjct: 592 EKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIR 651
Query: 113 RVKEKEREHERRKRHREEQ--DKARREWERQKRREMAREHSRRE 154
+EK RE E + +EE+ ++ + E++++ + E RR+
Sbjct: 652 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 695
Score = 50.1 bits (118), Expect = 8e-07
Identities = 36/153 (23%), Positives = 78/153 (50%), Gaps = 11/153 (7%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIR 63
E W+ + +EK R EQEEK + +++ +++ + E E R + E+ +
Sbjct: 476 EAKMWRQEEKIREQEEKIR--EQEEK-----MWRQEEKIHEQEKIREEEKRQEQEEMWRQ 528
Query: 64 NSPYRREDSM---EDRGEEDDSLAIKPPQQMSRKEKAHHRKDEK-RKEKRKHARVKEKER 119
R ++ + +++ E + K ++M R+E+ H ++EK R+++ K R +EK R
Sbjct: 529 EEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIR 588
Query: 120 EHERRKRHREEQDKARREWERQKRREMAREHSR 152
E E + R +EE+ + + E +++ +M + +
Sbjct: 589 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 621
Score = 48.9 bits (115), Expect = 2e-06
Identities = 27/150 (18%), Positives = 79/150 (52%), Gaps = 7/150 (4%)
Query: 9 KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYR 68
K+ ++I +E+KR++++E + ++++ ++ +++ + E E + + E +R
Sbjct: 506 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQE----EKMWR 561
Query: 69 REDSMEDRGE---EDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRK 125
+E+ M D+ E E + + +++ +E+ ++EK +E+ + + +E++ + K
Sbjct: 562 QEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 621
Query: 126 RHREEQDKARREWERQKRREMAREHSRRER 155
+E+ +E + +++ E RE ++ R
Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKIREQEKKIR 651
Score = 47.4 bits (111), Expect = 5e-06
Identities = 38/160 (23%), Positives = 80/160 (50%), Gaps = 13/160 (8%)
Query: 1 MGDEKDSWKVKTLDEILQEK--KRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRM 58
+G E S K ++ + + R +Q+E+ ++ + + + K EE ++R+
Sbjct: 331 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE-KIREQEE 389
Query: 59 EITIRNSPYRREDSM----EDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARV 114
+I + RR++ M E++ + + + ++M R+E+ K+EK +E +
Sbjct: 390 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 449
Query: 115 KEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 154
+EK RE E + R+E++K R E++KR+E + R+E
Sbjct: 450 QEKIREQEEK---RQEEEKIR---EQEKRQEQEAKMWRQE 483
Score = 46.2 bits (108), Expect = 1e-05
Identities = 29/133 (21%), Positives = 70/133 (52%), Gaps = 4/133 (3%)
Query: 9 KVKTLDEILQEKKRR-KEQEEKAEIKRLKNSDDRDS---KRDSLEEGELRDHRMEITIRN 64
K++ +E ++E++ + +EQEE + + K + + + + ++E E + R E IR
Sbjct: 586 KIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE 645
Query: 65 SPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERR 124
+ + E E+++ + + + ++EK ++++ ++++ K R +EK E E R
Sbjct: 646 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 705
Query: 125 KRHREEQDKARRE 137
R +EE+ + +E
Sbjct: 706 LRQQEEKMQEHQE 718
Score = 43.9 bits (102), Expect = 6e-05
Identities = 34/151 (22%), Positives = 78/151 (51%), Gaps = 15/151 (9%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSL----EEGELRDHRME 59
E+ W+ + + +EK + +E++ + + ++++ +++ +++ + EE R M
Sbjct: 360 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 419
Query: 60 ITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKER 119
R+E+ M ++ E+ L K +Q +E+ +EKR+E+ K R +EK +
Sbjct: 420 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ-----EEKRQEEEK-IREQEKRQ 473
Query: 120 EHERR-----KRHREEQDKARREWERQKRRE 145
E E + ++ RE+++K R + E+ R+E
Sbjct: 474 EQEAKMWRQEEKIREQEEKIREQEEKMWRQE 504
Score = 35.0 bits (79), Expect = 0.026
Identities = 24/129 (18%), Positives = 61/129 (47%), Gaps = 14/129 (10%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
M E++ + +++ +++++ +EQEEK + + + E E + E
Sbjct: 607 MTQEQEEKMGEQEEKMCEQEEKMQEQEEKMR-----------RQEEKIREQEKKIREQEE 655
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE 120
IR ++ E E+++ + + ++M +E+ R++EK E + R++++E +
Sbjct: 656 KIREQEEMMQEQEEKMWEQEEKMC-EQEEKMQEQEEKMRRQEEKMWE--QEVRLRQQEEK 712
Query: 121 HERRKRHRE 129
+ + H E
Sbjct: 713 MQEHQEHLE 721
Score = 33.5 bits (75), Expect = 0.075
Identities = 40/170 (23%), Positives = 77/170 (45%), Gaps = 26/170 (15%)
Query: 10 VKTLDEILQEKKRRKEQEE-KAEIKRL-KNSDDRDSKRDS-LEEGELRDHRMEITIRNSP 66
VK L L+ K Q++ +AE L K +K + +EE EL + R+
Sbjct: 305 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWN-RLNQQQEEKM 363
Query: 67 YRREDSM---EDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKER-EHE 122
+R+E+ + E++ +E + + +++ +E+ R++E EK + R +E+ E E
Sbjct: 364 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 423
Query: 123 RRKRHRE------------------EQDKARREWERQKRREMAREHSRRE 154
+ R +E EQ+K R + E+++ E RE +R+
Sbjct: 424 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 473
Score = 33.1 bits (74), Expect = 0.098
Identities = 36/156 (23%), Positives = 76/156 (48%), Gaps = 21/156 (13%)
Query: 14 DEILQEKKRRKEQE------EKAEI----KRLKNSDDRDSKRDSLEEGELRDHRMEITIR 63
DE L+EK + +++ EK+EI K LK +R ++ + + ++
Sbjct: 277 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 336
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKE-REHE 122
+ + + +E+ E + L + ++M R+E+ +EK +E+ + R +E++ RE E
Sbjct: 337 SVSAKLQAQVEEN-ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 395
Query: 123 RRKRHREE-----QDKARRE----WERQKRREMARE 149
+ R +EE ++K RR+ WE++++ E
Sbjct: 396 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 431
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 56.2 bits (134), Expect = 1e-08
Identities = 43/152 (28%), Positives = 70/152 (46%), Gaps = 15/152 (9%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEIT--IRNSP------ 66
E+L++ RKEQE E KR + D + E RD I +R++
Sbjct: 310 EVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPYAD 369
Query: 67 --YRREDSMEDRGEEDDSLAIKPPQQMSRKEKAH-HRKDEKRKEKRKHARVKEKEREHER 123
Y E RG + ++ + Q + E H +R+ E+ +E+ R +E+ERE +R
Sbjct: 370 PYYDYEIERFWRGGQYENFRV----QYTETEPYHNYRERERERERENRQRERERERERDR 425
Query: 124 RKRHREEQDKARREWERQKRREMAREHSRRER 155
+ R+ + + RE ER K R+ +E RER
Sbjct: 426 ERERRQREREREREHERDKERQRRKEEWERER 457
Score = 46.6 bits (109), Expect = 9e-06
Identities = 26/98 (26%), Positives = 52/98 (53%), Gaps = 6/98 (6%)
Query: 51 GELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRK 110
G+ + R++ T PY E E ++ + ++ +++ R+ +R+ +R+
Sbjct: 383 GQYENFRVQYT-ETEPYHNYRERERERERENRQ--RERERERERDRERERRQRERERERE 439
Query: 111 HARVKEKER---EHERRKRHREEQDKARREWERQKRRE 145
H R KE++R E ER + R+E+D+ R+ +R+K RE
Sbjct: 440 HERDKERQRRKEEWERERAKRDEKDRQHRDRDREKERE 477
Score = 39.3 bits (90), Expect = 0.001
Identities = 21/92 (22%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Query: 63 RNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHE 122
R RE+ +R E + + +Q R+ + H +D++R ++RK +E+ + E
Sbjct: 404 RERERERENRQRERERERERDRERERRQREREREREHERDKER-QRRKEEWERERAKRDE 462
Query: 123 RRKRHREEQDKARREWERQKRREMAREHSRRE 154
+ ++HR+ + RE E+ K + + + R+
Sbjct: 463 KDRQHRDRDREKEREKEKGKPKPRSPQPPSRQ 494
Score = 38.5 bits (88), Expect = 0.002
Identities = 31/147 (21%), Positives = 65/147 (44%), Gaps = 17/147 (11%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
+E++R +E+E + + + DR+ +R E R+H + + R+E+ +R
Sbjct: 402 RERERERERENRQRERERERERDRERERRQREREREREHERD---KERQRRKEEWERERA 458
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERR---------KRHR 128
+ D+ +Q +++ R+ EK K K + + ++ E ++ KR
Sbjct: 459 KRDEK-----DRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRAD 513
Query: 129 EEQDKARREWERQKRREMAREHSRRER 155
E +D RR +K+ ++ SR R
Sbjct: 514 EWKDPWRRSKSPKKKLGVSVSPSRARR 540
Score = 36.6 bits (83), Expect = 0.009
Identities = 32/155 (20%), Positives = 67/155 (43%), Gaps = 14/155 (9%)
Query: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEIT 61
G + ++++V+ + R +E+E + E ++ + +R+ R+ R+ R
Sbjct: 382 GGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRE-------RERRQRER 434
Query: 62 IRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREH 121
R + R+ + R EE + ++ R EK +D R+++R+ + K K R
Sbjct: 435 EREREHERDKERQRRKEEWER------ERAKRDEKDRQHRDRDREKEREKEKGKPKPRSP 488
Query: 122 ERRKRHREEQDK-ARREWERQKRREMAREHSRRER 155
+ R E K A + KR + ++ RR +
Sbjct: 489 QPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSK 523
Score = 30.8 bits (68), Expect = 0.49
Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 26 QEEKAEIKRLKNSDDRD---SKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDS 82
+EE E + + SD RD S L+E EL D+ E+ +P +ED E G EDD
Sbjct: 98 EEEGDEGEEDRTSDLRDEASSVTRELDEHEL-DYDEEVPEEPAPAVQEDEAEKAGAEDDE 156
Query: 83 LAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKE 118
+ + R+E + KE + A+ K+KE
Sbjct: 157 ---EKGEGTPREEGKAGVQSVGEKESLEAAKEKKKE 189
Score = 29.3 bits (64), Expect = 1.4
Identities = 15/41 (36%), Positives = 24/41 (58%), Gaps = 6/41 (14%)
Query: 15 EILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRD 55
E L+ K +K++++ EI DD + D LEEGE++D
Sbjct: 178 ESLEAAKEKKKEDDDGEI------DDGEIDDDDLEEGEVKD 212
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 55.8 bits (133), Expect = 1e-08
Identities = 30/149 (20%), Positives = 80/149 (53%), Gaps = 3/149 (2%)
Query: 9 KVKTLDEILQEKKR-RKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPY 67
K++ L+E + E+++ R+++E++ E ++++ + R + + E + E IR
Sbjct: 345 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 404
Query: 68 RREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRH 127
++ E GE+++ + + + ++EK ++++ R++++K +EK RE E +
Sbjct: 405 MMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 464
Query: 128 REEQ--DKARREWERQKRREMAREHSRRE 154
+EE+ ++ + E++ + + E RR+
Sbjct: 465 QEEKMGEQEGKMCEQEAKMQEQEEKMRRQ 493
Score = 53.5 bits (127), Expect = 7e-08
Identities = 33/152 (21%), Positives = 78/152 (51%), Gaps = 6/152 (3%)
Query: 9 KVKTLDEILQEKKRRK-EQEEKAEIKRLKNSDDRDSKR---DSLEEGELRDHRMEITIRN 64
K++ +E++QE++ + EQEEK + + + + R + + E E + E IR
Sbjct: 398 KIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457
Query: 65 SPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERR 124
++ E GE++ + + + ++EK ++++ R++++K +EK RE E
Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 517
Query: 125 KRHREEQ--DKARREWERQKRREMAREHSRRE 154
+ +EE+ ++ + E++++ + E RR+
Sbjct: 518 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 549
Score = 50.8 bits (120), Expect = 5e-07
Identities = 32/149 (21%), Positives = 75/149 (50%), Gaps = 9/149 (6%)
Query: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIR 63
E+ W+ + L+EK +E+ + E KR +++ +++ +E E + R E IR
Sbjct: 336 EEMMWEKEEKIRELEEKMHEQEKIREQEEKR--QEEEKIREQEKRQEQEAKMWRQEEKIR 393
Query: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHER 123
+ + E E+++ + ++EK +++E ++++ K R +EK RE E+
Sbjct: 394 EQEEKIREQEEMMQEQEEKMG-------EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEK 446
Query: 124 RKRHREEQDKARREWERQKRREMAREHSR 152
+ R +EE+ + + E +++ +M + +
Sbjct: 447 KIREQEEKIREQEEMMQEQEEKMGEQEGK 475
Score = 46.6 bits (109), Expect = 9e-06
Identities = 27/161 (16%), Positives = 83/161 (51%), Gaps = 14/161 (8%)
Query: 1 MGDEKDS-WKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSL----------E 49
MG++++ W+ + + +EK RR+E++ + + K+++ +++ +++ + +
Sbjct: 413 MGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ 472
Query: 50 EGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKR 109
EG++ + ++ + RR+ E++ E + + +++ +E+ ++EK E+
Sbjct: 473 EGKMCEQEAKMQEQEEKMRRQ---EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 529
Query: 110 KHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREH 150
+ +E++ + + K R+E+ +E +++ E +EH
Sbjct: 530 EKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 44.7 bits (104), Expect = 3e-05
Identities = 35/158 (22%), Positives = 77/158 (48%), Gaps = 15/158 (9%)
Query: 9 KVKTLDEILQEKKRR-KEQEEKA----------EIKRLKNSDDRDSKRDSLEEGELRDHR 57
K++ +E +QE++ + +EQEEK E K + + K + + E E + H
Sbjct: 296 KIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 355
Query: 58 MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEK 117
E IR +R++ + R +E + +M R+E+ ++EK +E+ + + +E+
Sbjct: 356 QE-KIREQEEKRQEEEKIREQEKRQ---EQEAKMWRQEEKIREQEEKIREQEEMMQEQEE 411
Query: 118 EREHERRKRHREEQDKARREWERQKRREMAREHSRRER 155
+ + K +E++ +E + +++ E RE ++ R
Sbjct: 412 KMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Score = 40.8 bits (94), Expect = 5e-04
Identities = 34/155 (21%), Positives = 70/155 (45%), Gaps = 10/155 (6%)
Query: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60
+G E S K L ++E + ++ E K + + + + ++E E + E
Sbjct: 258 LGKELQSVSAK-LQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEE 316
Query: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE 120
+R R+E+ M ++ E+ + + M KE+ +EK E+ K +EK +E
Sbjct: 317 KMR----RQEEMMWEKEEK----MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 368
Query: 121 HERRKRHREEQDKARREWERQKRREMAREHSRRER 155
E+ + + Q++ + W RQ+ + +E RE+
Sbjct: 369 EEKIREQEKRQEQEAKMW-RQEEKIREQEEKIREQ 402
Score = 39.7 bits (91), Expect = 0.001
Identities = 29/139 (20%), Positives = 69/139 (49%), Gaps = 14/139 (10%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
Q++++ QEEK + + K + + R+ EE R M R+E+ M ++
Sbjct: 285 QQEEKMWRQEEKIQEREEKIQEQEEKIREQ-EEKMRRQEEMMWEKEEKMRRQEEMMWEKE 343
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKD--EKRKEKRKHARVKEKEREHERRKRHREEQDKAR 135
E+ L +EK H ++ E+ +++++ +++E+E+ E+ + +++K R
Sbjct: 344 EKIREL----------EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 393
Query: 136 REWER-QKRREMAREHSRR 153
+ E+ +++ EM +E +
Sbjct: 394 EQEEKIREQEEMMQEQEEK 412
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 55.8 bits (133), Expect = 1e-08
Identities = 49/169 (28%), Positives = 80/169 (47%), Gaps = 21/169 (12%)
Query: 2 GDEKDSW--KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRME 59
GD+K++ KT + +E+KR E+ EK E K K + +D K D+ G+ +
Sbjct: 465 GDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSE---- 520
Query: 60 ITIRNSPYRREDSMEDRGE----EDDSLAIKPPQQMSRKEKAHHRKDEKR-----KEKRK 110
+I+ S ++ S + G + P + R EK H R EK K++ K
Sbjct: 521 -SIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDK 579
Query: 111 HARVKE----KEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 155
R KE ++ + +R + H ++ RR E ++RRE+A E RRER
Sbjct: 580 DYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIA-ERERRER 627
Score = 41.6 bits (96), Expect = 3e-04
Identities = 36/137 (26%), Positives = 71/137 (51%), Gaps = 10/137 (7%)
Query: 23 RKEQEEKAEIKRLKNSDDRDSKR---DSLEEGELRDH--RMEITIRNSPYRREDSMEDRG 77
R +++E+A + + ++ D R + + ++E LR+H R E R RR + +R
Sbjct: 564 RSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAER- 622
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARRE 137
E + I+ ++ +E+ ++ E++K R + ERE R+R R EQ++ R+E
Sbjct: 623 ERRERERIRIIREREERERLQRERERLEIERQKLER-ERMERERLERERIRIEQER-RKE 680
Query: 138 WER--QKRREMAREHSR 152
ER ++R E+ R+ +
Sbjct: 681 AERIAREREELRRQQQQ 697
Score = 33.5 bits (75), Expect = 0.075
Identities = 32/140 (22%), Positives = 61/140 (43%), Gaps = 16/140 (11%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
++ K ++ +E +RL+ + + +R+ E R+ I R + E
Sbjct: 590 EKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRII------REREERERLQ 643
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKR----KEKRKHARVKEKEREHERRKRHREEQDK 133
E + L I+ Q++ R+ R + +R +E+RK A +ERE RR +Q +
Sbjct: 644 RERERLEIER-QKLERERMERERLERERIRIEQERRKEAERIAREREELRR-----QQQQ 697
Query: 134 ARREWERQKRREMAREHSRR 153
R E E++ + R+ R
Sbjct: 698 LRYEQEKRNSLKRPRDVDHR 717
>gi|63176611 modulator of estrogen induced transcription isoform a
[Homo sapiens]
Length = 1034
Score = 55.8 bits (133), Expect = 1e-08
Identities = 49/169 (28%), Positives = 80/169 (47%), Gaps = 21/169 (12%)
Query: 2 GDEKDSW--KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRME 59
GD+K++ KT + +E+KR E+ EK E K K + +D K D+ G+ +
Sbjct: 483 GDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASGQTSE---- 538
Query: 60 ITIRNSPYRREDSMEDRGE----EDDSLAIKPPQQMSRKEKAHHRKDEKR-----KEKRK 110
+I+ S ++ S + G + P + R EK H R EK K++ K
Sbjct: 539 -SIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKIHGRSKEKERASLDKKRDK 597
Query: 111 HARVKE----KEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 155
R KE ++ + +R + H ++ RR E ++RRE+A E RRER
Sbjct: 598 DYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIA-ERERRER 645
Score = 41.6 bits (96), Expect = 3e-04
Identities = 36/137 (26%), Positives = 71/137 (51%), Gaps = 10/137 (7%)
Query: 23 RKEQEEKAEIKRLKNSDDRDSKR---DSLEEGELRDH--RMEITIRNSPYRREDSMEDRG 77
R +++E+A + + ++ D R + + ++E LR+H R E R RR + +R
Sbjct: 582 RSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREIAER- 640
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARRE 137
E + I+ ++ +E+ ++ E++K R + ERE R+R R EQ++ R+E
Sbjct: 641 ERRERERIRIIREREERERLQRERERLEIERQKLER-ERMERERLERERIRIEQER-RKE 698
Query: 138 WER--QKRREMAREHSR 152
ER ++R E+ R+ +
Sbjct: 699 AERIAREREELRRQQQQ 715
Score = 33.5 bits (75), Expect = 0.075
Identities = 32/140 (22%), Positives = 61/140 (43%), Gaps = 16/140 (11%)
Query: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRG 77
++ K ++ +E +RL+ + + +R+ E R+ I R + E
Sbjct: 608 EKMKEQRLREHLVRFERLRRAMELRRRREIAERERRERERIRII------REREERERLQ 661
Query: 78 EEDDSLAIKPPQQMSRKEKAHHRKDEKR----KEKRKHARVKEKEREHERRKRHREEQDK 133
E + L I+ Q++ R+ R + +R +E+RK A +ERE RR +Q +
Sbjct: 662 RERERLEIER-QKLERERMERERLERERIRIEQERRKEAERIAREREELRR-----QQQQ 715
Query: 134 ARREWERQKRREMAREHSRR 153
R E E++ + R+ R
Sbjct: 716 LRYEQEKRNSLKRPRDVDHR 735
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 55.5 bits (132), Expect = 2e-08
Identities = 33/132 (25%), Positives = 75/132 (56%), Gaps = 8/132 (6%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSM 73
+E+ ++++ +EQ+ + E++R + +R +R+ LE L R+E +E
Sbjct: 138 EELEIQRRQLQEQQRQKELERERLERER-MERERLERERLERERLE----RERLEQEQLE 192
Query: 74 EDRGEEDDSLAIKPPQQMSRKEK--AHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQ 131
+R E + ++ +++ R+E+ R D +R+E+++ R++ ERE + R+R +E+
Sbjct: 193 RERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERER-QEQL 251
Query: 132 DKARREWERQKR 143
++ + EWER++R
Sbjct: 252 EREQLEWERERR 263
Score = 41.2 bits (95), Expect = 4e-04
Identities = 20/79 (25%), Positives = 40/79 (50%)
Query: 77 GEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARR 136
G + L I+ Q ++ + ++ +E+ + R++ + E ER +R R EQ++ R
Sbjct: 134 GPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLER 193
Query: 137 EWERQKRREMAREHSRRER 155
E + ++R+E R ER
Sbjct: 194 ERQERERQERLERQERLER 212
Score = 39.7 bits (91), Expect = 0.001
Identities = 26/110 (23%), Positives = 53/110 (48%), Gaps = 1/110 (0%)
Query: 47 SLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRK 106
S EE E++ +++ R RE +R E + + ++ +E+ + E+ +
Sbjct: 136 SQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERER 195
Query: 107 EKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAR-EHSRRER 155
++R+ E++ ER++R ++ R ERQ+R + R E R+ER
Sbjct: 196 QERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQER 245
Score = 37.4 bits (85), Expect = 0.005
Identities = 25/139 (17%), Positives = 61/139 (43%), Gaps = 6/139 (4%)
Query: 23 RKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDS 82
R+ + A+++ + ++ + +R L+E + + + RE +R E +
Sbjct: 122 RQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERL 181
Query: 83 LAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARRE----- 137
+ Q+ +E+ + E+ + + + R + ER+ + +E Q++ R E
Sbjct: 182 ERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERE 241
Query: 138 -WERQKRREMAREHSRRER 155
ER+++ ++ RE ER
Sbjct: 242 RQERERQEQLEREQLEWER 260
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 55.5 bits (132), Expect = 2e-08
Identities = 33/132 (25%), Positives = 75/132 (56%), Gaps = 8/132 (6%)
Query: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSM 73
+E+ ++++ +EQ+ + E++R + +R +R+ LE L R+E +E
Sbjct: 138 EELEIQRRQLQEQQRQKELERERLERER-MERERLERERLERERLE----RERLEQEQLE 192
Query: 74 EDRGEEDDSLAIKPPQQMSRKEK--AHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQ 131
+R E + ++ +++ R+E+ R D +R+E+++ R++ ERE + R+R +E+
Sbjct: 193 RERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERER-QEQL 251
Query: 132 DKARREWERQKR 143
++ + EWER++R
Sbjct: 252 EREQLEWERERR 263
Score = 41.2 bits (95), Expect = 4e-04
Identities = 20/79 (25%), Positives = 40/79 (50%)
Query: 77 GEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARR 136
G + L I+ Q ++ + ++ +E+ + R++ + E ER +R R EQ++ R
Sbjct: 134 GPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLER 193
Query: 137 EWERQKRREMAREHSRRER 155
E + ++R+E R ER
Sbjct: 194 ERQERERQERLERQERLER 212
Score = 39.7 bits (91), Expect = 0.001
Identities = 26/110 (23%), Positives = 53/110 (48%), Gaps = 1/110 (0%)
Query: 47 SLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRK 106
S EE E++ +++ R RE +R E + + ++ +E+ + E+ +
Sbjct: 136 SQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERER 195
Query: 107 EKRKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAR-EHSRRER 155
++R+ E++ ER++R ++ R ERQ+R + R E R+ER
Sbjct: 196 QERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQER 245
Score = 37.4 bits (85), Expect = 0.005
Identities = 25/139 (17%), Positives = 61/139 (43%), Gaps = 6/139 (4%)
Query: 23 RKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDS 82
R+ + A+++ + ++ + +R L+E + + + RE +R E +
Sbjct: 122 RQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERL 181
Query: 83 LAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKEREHERRKRHREEQDKARRE----- 137
+ Q+ +E+ + E+ + + + R + ER+ + +E Q++ R E
Sbjct: 182 ERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERE 241
Query: 138 -WERQKRREMAREHSRRER 155
ER+++ ++ RE ER
Sbjct: 242 RQERERQEQLEREQLEWER 260
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.125 0.340
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,687,517
Number of Sequences: 37866
Number of extensions: 355030
Number of successful extensions: 18880
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 824
Number of HSP's successfully gapped in prelim test: 744
Number of HSP's that attempted gapping in prelim test: 3877
Number of HSP's gapped (non-prelim): 7602
length of query: 155
length of database: 18,247,518
effective HSP length: 93
effective length of query: 62
effective length of database: 14,725,980
effective search space: 913010760
effective search space used: 913010760
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.