Guide to the Human Genome
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Search of human proteins with 110624765

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110624765 POU domain, class 3, transcription factor 1 [Homo
sapiens]
         (451 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110624765 POU domain, class 3, transcription factor 1 [Homo s...   956   0.0  
gi|5453936 POU class 3 homeobox 3 [Homo sapiens]                      370   e-102
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa...   360   1e-99
gi|110624763 POU domain, class 3, transcription factor 4 [Homo s...   310   1e-84
gi|148664218 POU transcription factor [Homo sapiens]                  207   2e-53
gi|42560248 POU domain, class 5, transcription factor 1 isoform ...   202   5e-52
gi|42476164 POU class 2 homeobox 1 [Homo sapiens]                     202   7e-52
gi|4505959 POU domain, class 2, transcription factor 2 [Homo sap...   198   7e-51
gi|227430410 POU class 5 homeobox 1B [Homo sapiens]                   197   2e-50
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s...   194   1e-49
gi|116235491 POU domain, class 5, transcription factor 1 isoform...   189   6e-48
gi|170650730 pituitary specific transcription factor 1 isoform b...   181   1e-45
gi|4505955 pituitary specific transcription factor 1 isoform alp...   181   1e-45
gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]     169   5e-42
gi|4505965 POU class 4 homeobox 3 [Homo sapiens]                      155   5e-38
gi|23463326 POU domain class 5, transcription factor 2 [Homo sap...   139   5e-33
gi|223890225 POU class 6 homeobox 1 [Homo sapiens]                    127   2e-29
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s...   101   2e-21
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    72   1e-12
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    72   1e-12
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    72   1e-12
gi|89257348 homeo box HB9 [Homo sapiens]                               62   8e-10
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    62   1e-09
gi|40288197 GATA binding protein 6 [Homo sapiens]                      62   1e-09
gi|71274111 v-maf musculoaponeurotic fibrosarcoma oncogene homol...    62   1e-09
gi|195972866 keratin 10 [Homo sapiens]                                 61   2e-09
gi|109452587 family with sequence similarity 98, member B isofor...    59   7e-09
gi|55956899 keratin 9 [Homo sapiens]                                   59   1e-08
gi|226437602 NK1 homeobox 2 [Homo sapiens]                             57   3e-08
gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  57   3e-08

>gi|110624765 POU domain, class 3, transcription factor 1 [Homo
           sapiens]
          Length = 451

 Score =  956 bits (2470), Expect = 0.0
 Identities = 451/451 (100%), Positives = 451/451 (100%)

Query: 1   MATTAQYLPRGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGA 60
           MATTAQYLPRGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGA
Sbjct: 1   MATTAQYLPRGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGA 60

Query: 61  GAGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQG 120
           GAGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQG
Sbjct: 61  GAGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQG 120

Query: 121 AAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGG 180
           AAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGG
Sbjct: 121 AAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGG 180

Query: 181 GGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSS 240
           GGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSS
Sbjct: 181 GGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSS 240

Query: 241 VGEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQ 300
           VGEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQ
Sbjct: 241 VGEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQ 300

Query: 301 LSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLK 360
           LSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLK
Sbjct: 301 LSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLK 360

Query: 361 CPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPG 420
           CPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPG
Sbjct: 361 CPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPG 420

Query: 421 GGGASPPSAPPPPPPAALHHHHHHTLPGSVQ 451
           GGGASPPSAPPPPPPAALHHHHHHTLPGSVQ
Sbjct: 421 GGGASPPSAPPPPPPAALHHHHHHTLPGSVQ 451


>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
          Length = 500

 Score =  370 bits (951), Expect = e-102
 Identities = 251/502 (50%), Positives = 271/502 (53%), Gaps = 101/502 (20%)

Query: 11  GPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQK-LMHHEWLGAGAGHPVGLA 69
           G GGGAGG G  M P +AA  + A   +     ++ + VQ   M      +  GH +  A
Sbjct: 39  GGGGGAGGGGGGMQPGSAAVTSGAYRGD----PSSVKMVQSDFMQGAMAASNGGHMLSHA 94

Query: 70  HPQW---LPTGGG-----------GGGDWAGG---------------PHLEHGKAGGGGT 100
           H QW   LP                   W+G                P    G    GG 
Sbjct: 95  H-QWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGA 153

Query: 101 GRADDGGGGGGFHAR----------LVHQG-------AAHAGAAWAQGSTAHHLGPAMSP 143
           GR DD   G   H R            HQG       AA A AA A  + A HL      
Sbjct: 154 GR-DDLHAGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHL------ 206

Query: 144 SPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAA------GGGGAGPGLHHALHEDGHE 197
            P  +GG QP P  L     Y   GG  + GML+A      GGGGAG G    +H     
Sbjct: 207 -PSMAGGQQPPPQSL----LYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPG--- 258

Query: 198 AQLEPSPPPHLGA---HGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVG-----EHSDEDA 249
             L     P L     H H H H H    H A    H G GGGG+  G      HSDED 
Sbjct: 259 --LVRGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGGGGGGAGPGLNSHDPHSDEDT 316

Query: 250 PSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKL 309
           P+SDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKL
Sbjct: 317 PTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKL 376

Query: 310 KPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCPKPSAHEI 369
           KPLLNKWLEE DSS+GSPT++DKIAAQGRKRKKRTSIEV VKGALESHFLKCPKPSA EI
Sbjct: 377 KPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEI 436

Query: 370 TGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPGGGGASPPSA 429
           T LADSLQLEKEVVRVWFCNRRQKEKRMTP  G      DDVY+              SA
Sbjct: 437 TNLADSLQLEKEVVRVWFCNRRQKEKRMTP-PGIQQQTPDDVYSQ---------VGTVSA 486

Query: 430 PPPPPPAALHHHHHHTLPGSVQ 451
             PPP        HH L  SVQ
Sbjct: 487 DTPPP--------HHGLQTSVQ 500



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 64/206 (31%), Positives = 72/206 (34%), Gaps = 51/206 (24%)

Query: 68  LAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFH--ARLVHQGAAHAG 125
           + H      GGGGGG             GGGG G A  GGGGGG    +  V  GA    
Sbjct: 21  IVHSDAAGAGGGGGG------------GGGGGGGGA--GGGGGGMQPGSAAVTSGAYRGD 66

Query: 126 AAWAQGSTAHHLGPAMSPSPGA---SGGHQ-----PQPLGLYAQAAYP--------GGGG 169
            +  +   +  +  AM+ S G    S  HQ     P      A AA           G  
Sbjct: 67  PSSVKMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSA 126

Query: 170 GGLAGMLA--------------AGGGGAGPGLH--HALHEDGHEAQLEPSPPPHL---GA 210
            G+AG                   GG     LH   ALH  G      P PPPH    G 
Sbjct: 127 VGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHHRGPPHLGPPPPPPHQGHPGG 186

Query: 211 HGHAHGHAHAGGLHAAAAHLHPGAGG 236
            G A   A A    AAAAHL   AGG
Sbjct: 187 WGAAAAAAAAAAAAAAAAHLPSMAGG 212



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 32/115 (27%), Positives = 44/115 (38%), Gaps = 22/115 (19%)

Query: 158 LYAQAAYPGGGGGGLAGMLAAGGGGAGPGLH------------------HALHEDGHEAQ 199
           +++ AA  GGGGGG  G    G GG G G+                     +  D  +  
Sbjct: 22  VHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGA 81

Query: 200 LEPSPPPHLGAHGH----AHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAP 250
           +  S   H+ +H H    A  HA A    AAAA +   +   GS+VG       P
Sbjct: 82  MAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQP 136



 Score = 37.7 bits (86), Expect = 0.021
 Identities = 32/100 (32%), Positives = 36/100 (36%), Gaps = 18/100 (18%)

Query: 9   PRGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLM--HHEWLGAGAGHPV 66
           P GPGGG GG G               A   +H G    +  +L   HH        HP 
Sbjct: 237 PPGPGGGGGGAG-------------GGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPP 283

Query: 67  GLAHPQWLPTGGGGGGDWAGGPHL-EHGKAGGGGTGRADD 105
              H Q  P  GGGGG    GP L  H       T  +DD
Sbjct: 284 HPHHAQGPPHHGGGGG--GAGPGLNSHDPHSDEDTPTSDD 321


>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
           sapiens]
          Length = 443

 Score =  360 bits (924), Expect = 1e-99
 Identities = 228/436 (52%), Positives = 248/436 (56%), Gaps = 89/436 (20%)

Query: 46  YREVQKLMHHEWLGA--GAGHPVGLAHPQWLPT---GGGGGGDWAGGPHLEHGKAGGGGT 100
           YRE Q L+  ++ GA    GHP+  AH QW+     GGGGGG   GG     G  GG G+
Sbjct: 34  YREAQSLVQGDY-GALQSNGHPLSHAH-QWITALSHGGGGGGGGGGGGGGGGGGGGGDGS 91

Query: 101 ---------------------GRADDGGGGGGFHAR------------------------ 115
                                GR D+  G G    +                        
Sbjct: 92  PWSTSPLGQPDIKPSVVVQQGGRGDELHGPGALQQQHQQQQQQQQQQQQQQQQQQQQQRP 151

Query: 116 --LVHQGAAH--AGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGG 171
             LVH  A H     AW   + A HL P+M  S G           LY+Q ++       
Sbjct: 152 PHLVHHAANHHPGPGAWRSAAAAAHLPPSMGASNGGL---------LYSQPSFT------ 196

Query: 172 LAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLH 231
           + GML AGG  AG  LHH    D H+       P H   H H H H H            
Sbjct: 197 VNGMLGAGGQPAG--LHHHGLRDAHDE------PHHADHHPHPHSHPHQQPPPPPPPQGP 248

Query: 232 PGAGGGGSSVGEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQT 291
           PG  G       HSDED P+SDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQT
Sbjct: 249 PGHPGAHHD--PHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQT 306

Query: 292 TICRFEALQLSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVK 351
           TICRFEALQLSFKNMCKLKPLLNKWLEE DSSSGSPT++DKIAAQGRKRKKRTSIEV VK
Sbjct: 307 TICRFEALQLSFKNMCKLKPLLNKWLEEADSSSGSPTSIDKIAAQGRKRKKRTSIEVSVK 366

Query: 352 GALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDV 411
           GALESHFLKCPKPSA EIT LADSLQLEKEVVRVWFCNRRQKEKRMTP  G   P  +DV
Sbjct: 367 GALESHFLKCPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGT-LPGAEDV 425

Query: 412 YAPGELGPGGGGASPP 427
           Y       GG   +PP
Sbjct: 426 Y-------GGSRDTPP 434


>gi|110624763 POU domain, class 3, transcription factor 4 [Homo
           sapiens]
          Length = 361

 Score =  310 bits (795), Expect = 1e-84
 Identities = 191/380 (50%), Positives = 223/380 (58%), Gaps = 60/380 (15%)

Query: 22  LMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGA--GAGHPVGLAHPQWLPTGGG 79
           L+H D+A           +  G+ +R  QKL+  ++L      GHP+G     W+ T   
Sbjct: 17  LVHADSAG----------MQQGSPFRNPQKLLQSDYLQGVPSNGHPLG---HHWV-TSLS 62

Query: 80  GGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGSTAHHLGP 139
            GG W+               GR D   G       ++H  + H   A     T H    
Sbjct: 63  DGGPWSSTLATSPLDQQDVKPGREDLQLGA------IIHHRSPHV--AHHSPHTNHPNAW 114

Query: 140 AMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQ 199
             SP+P  S     QPL +Y+Q  +       ++GML  GG    P    A  +  H   
Sbjct: 115 GASPAPNPSITSSGQPLNVYSQPGFT------VSGMLEHGGLTPPPAAASA--QSLHPVL 166

Query: 200 LEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSSDDLEQFA 259
            EP     LG+H H                             +HSDE+ P+SD+LEQFA
Sbjct: 167 REPPDHGELGSH-HCQ---------------------------DHSDEETPTSDELEQFA 198

Query: 260 KQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEE 319
           KQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFE LQLSFKNMCKLKPLLNKWLEE
Sbjct: 199 KQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEGLQLSFKNMCKLKPLLNKWLEE 258

Query: 320 TDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLE 379
            DSS+GSPT++DKIAAQGRKRKKRTSIEV VKG LE+HFLKCPKP+A EI+ LADSLQLE
Sbjct: 259 ADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLADSLQLE 318

Query: 380 KEVVRVWFCNRRQKEKRMTP 399
           KEVVRVWFCNRRQKEKRMTP
Sbjct: 319 KEVVRVWFCNRRQKEKRMTP 338


>gi|148664218 POU transcription factor [Homo sapiens]
          Length = 436

 Score =  207 bits (527), Expect = 2e-53
 Identities = 135/277 (48%), Positives = 157/277 (56%), Gaps = 49/277 (17%)

Query: 184 GPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGE 243
           GPGL  A    GH      S  PHL A  H     H            P +GG       
Sbjct: 142 GPGL--ASQAFGHPGLPGSSLEPHLEASQHLPVPKHL-----------PSSGGA------ 182

Query: 244 HSDEDAPSS-DDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLS 302
               D PS  ++LE+FAK FKQRRIKLGFTQ DVGLA+G LYGN FSQTTI RFEAL LS
Sbjct: 183 ----DEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLS 238

Query: 303 FKNMCKLKPLLNKWLEETDSSSGSPT--------NLDKIAAQGRKRKKRTSIEVGVKGAL 354
           FKNMCKLKPLL KWL + +SS   P+        +L ++   GRKRKKRTSIE  ++  L
Sbjct: 239 FKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVF--GRKRKKRTSIETNIRLTL 296

Query: 355 ESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMT-PAAGAGHPPMDDVYA 413
           E  F   PKPS+ EI+ +A+ L +EKEVVRVWFCNRRQKEKR+  P A    PP   VY 
Sbjct: 297 EKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPP---VYN 353

Query: 414 PGELGPGGGGASPPSAPPPPPPAALHHHHHHTLPGSV 450
              + P  G   P S PP           H T+PG+V
Sbjct: 354 SRLVSP-SGSLGPLSVPPV----------HSTMPGTV 379


>gi|42560248 POU domain, class 5, transcription factor 1 isoform 1
           [Homo sapiens]
          Length = 360

 Score =  202 bits (514), Expect = 5e-52
 Identities = 136/320 (42%), Positives = 168/320 (52%), Gaps = 56/320 (17%)

Query: 159 YAQAAYPGGGGGGLAG----------MLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHL 208
           +A +  PGGGG G  G           L+  G   GPG+   +        + P PPP+ 
Sbjct: 9   FAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYE 68

Query: 209 GAHGHAH-------GHAHAGGLHAAAAHLHPGAGGGGSSVG------------------- 242
              G A+       G    GGL  +      G G   +S G                   
Sbjct: 69  FCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPGAVKLEKEK 128

Query: 243 -----EHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFE 297
                E S +      +LEQFAK  KQ+RI LG+TQADVGL LG L+G VFSQTTICRFE
Sbjct: 129 LEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFE 188

Query: 298 ALQLSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIA-----AQGRKRKKRTSIEVGVKG 352
           ALQLSFKNMCKL+PLL KW+EE D++     NL +I       Q RKR KRTSIE  V+G
Sbjct: 189 ALQLSFKNMCKLRPLLQKWVEEADNNE----NLQEICKAETLVQARKR-KRTSIENRVRG 243

Query: 353 ALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVY 412
            LE+ FL+CPKP+  +I+ +A  L LEK+VVRVWFCNRRQK KR    + + +   +D  
Sbjct: 244 NLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKR----SSSDYAQREDFE 299

Query: 413 APGELGPGGGGASPPSAPPP 432
           A G     GG  S P AP P
Sbjct: 300 AAGS-PFSGGPVSFPLAPGP 318


>gi|42476164 POU class 2 homeobox 1 [Homo sapiens]
          Length = 743

 Score =  202 bits (513), Expect = 7e-52
 Identities = 104/165 (63%), Positives = 124/165 (75%), Gaps = 7/165 (4%)

Query: 247 EDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM 306
           E+    ++LEQFAK FKQRRIKLGFTQ DVGLA+G LYGN FSQTTI RFEAL LSFKNM
Sbjct: 280 EEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNM 339

Query: 307 CKLKPLLNKWLEE-----TDSSSGSPTNLDKIAAQG--RKRKKRTSIEVGVKGALESHFL 359
           CKLKPLL KWL +     +DSS  SP+ L+    +G  R+RKKRTSIE  ++ ALE  FL
Sbjct: 340 CKLKPLLEKWLNDAENLSSDSSLSSPSALNSPGIEGLSRRRKKRTSIETNIRVALEKSFL 399

Query: 360 KCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAG 404
           +  KP++ EIT +AD L +EKEV+RVWFCNRRQKEKR+ P +  G
Sbjct: 400 ENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKRINPPSSGG 444


>gi|4505959 POU domain, class 2, transcription factor 2 [Homo
           sapiens]
          Length = 463

 Score =  198 bits (504), Expect = 7e-51
 Identities = 122/246 (49%), Positives = 140/246 (56%), Gaps = 58/246 (23%)

Query: 247 EDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM 306
           E+    ++LEQFA+ FKQRRIKLGFTQ DVGLA+G LYGN FSQTTI RFEAL LSFKNM
Sbjct: 179 EEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNM 238

Query: 307 CKLKPLLNKWLEET-----DSSSGSPTNLDKIAA-----QGRKRKKRTSIEVGVKGALES 356
           CKLKPLL KWL +      DSS  SP  L   +       GR+RKKRTSIE  V+ ALE 
Sbjct: 239 CKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEK 298

Query: 357 HFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRM------------------- 397
            FL   KP++ EI  +A+ L +EKEV+RVWFCNRRQKEKR+                   
Sbjct: 299 SFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPASYS 358

Query: 398 ----TPAAGAGHPPMDDVY------------APGELGP--------GGGGASP-----PS 428
               TP  GAG  P+                A G L P        GGGGA+P     PS
Sbjct: 359 PHMVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPS 418

Query: 429 APPPPP 434
             PPPP
Sbjct: 419 VTPPPP 424


>gi|227430410 POU class 5 homeobox 1B [Homo sapiens]
          Length = 359

 Score =  197 bits (500), Expect = 2e-50
 Identities = 136/323 (42%), Positives = 168/323 (52%), Gaps = 60/323 (18%)

Query: 159 YAQAAYPGGGGGGLAGM----------LAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHL 208
           +A +  PGGGG G  G           L+  G   GPG+   +        + P PPP+ 
Sbjct: 9   FAFSPPPGGGGDGPWGAEPGWVDPLTWLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYE 68

Query: 209 GAHGHAH-------GHAHAGGLHAAAAHLHPGAGGGGSSVG------------------- 242
              G A+       G    GGL  +      G G   +S G                   
Sbjct: 69  LCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPPGAVKLEKEK 128

Query: 243 -----EHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFE 297
                E S +      +LEQFAK  KQ+RI LG+TQADVGL LG L+G VFSQ TICRFE
Sbjct: 129 LEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQKTICRFE 188

Query: 298 ALQLSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIA-----AQGRKRKKRTSIEVGVKG 352
           ALQLSFKNMCKL+PLL KW+EE D++     NL +I       Q RKR KRTSIE  V+G
Sbjct: 189 ALQLSFKNMCKLRPLLQKWVEEADNNE----NLQEICKAETLMQARKR-KRTSIENRVRG 243

Query: 353 ALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVY 412
            LE+ FL+CPKP+  +I+ +A  L LEK+VVRVWFCNRRQK KR    + + +   +D  
Sbjct: 244 NLENLFLQCPKPTL-QISHIAQQLGLEKDVVRVWFCNRRQKGKR----SSSDYAQREDFE 298

Query: 413 APGELGPGGGGASPPSAPPPPPP 435
           A G    GG    P S PP P P
Sbjct: 299 AAGSPFSGG----PVSFPPAPGP 317


>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
           sapiens]
          Length = 419

 Score =  194 bits (493), Expect = 1e-49
 Identities = 129/314 (41%), Positives = 156/314 (49%), Gaps = 40/314 (12%)

Query: 95  AGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQ 154
           AG GG G A  GGG         H G    G     G      GP   P  G  GG    
Sbjct: 129 AGAGGAGAAAGGGGA--------HDGPGGGGGPGGGG------GPGGGPGGGGGGG---- 170

Query: 155 PLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLH---HALHEDGHEAQLEPSPPPHLGAH 211
                     PGGGGGG  G L  G     P +H   H  H     A   PS  PH G  
Sbjct: 171 ----------PGGGGGGPGGGLLGGSAHPHPHMHSLGHLSHPAAAAAMNMPSGLPHPGLV 220

Query: 212 GHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSSD----DLEQFAKQFKQRRI 267
             A  H  A    AAAA     A    + VG         SD    +LE FA++FKQRRI
Sbjct: 221 AAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDSDTDPRELEAFAERFKQRRI 280

Query: 268 KLGFTQADVGLALGTL----YGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEETDSS 323
           KLG TQADVG AL  L     G++ SQ+TICRFE+L LS  NM  LKP+L  WLEE + +
Sbjct: 281 KLGVTQADVGSALANLKIPGVGSL-SQSTICRFESLTLSHNNMIALKPILQAWLEEAEGA 339

Query: 324 SGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVV 383
                N  ++   G K++KRTSI    K +LE++F   P+PS+ +I  +A+ L L+K VV
Sbjct: 340 QREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVV 399

Query: 384 RVWFCNRRQKEKRM 397
           RVWFCN+RQK+KRM
Sbjct: 400 RVWFCNQRQKQKRM 413



 Score = 28.9 bits (63), Expect = 10.0
 Identities = 23/69 (33%), Positives = 27/69 (39%), Gaps = 12/69 (17%)

Query: 11  GPGGGAGGTG-----------PLMHPDAAAAAAAAAAAERLHAGAAYRE-VQKLMHHEWL 58
           GPGGG GG G           P MH     +  AAAAA  + +G  +   V    HH   
Sbjct: 170 GPGGGGGGPGGGLLGGSAHPHPHMHSLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAA 229

Query: 59  GAGAGHPVG 67
            A A    G
Sbjct: 230 AAAAAAAAG 238


>gi|116235491 POU domain, class 5, transcription factor 1 isoform 2
           [Homo sapiens]
          Length = 265

 Score =  189 bits (479), Expect = 6e-48
 Identities = 107/184 (58%), Positives = 128/184 (69%), Gaps = 15/184 (8%)

Query: 254 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLL 313
           +LEQFAK  KQ+RI LG+TQADVGL LG L+G VFSQTTICRFEALQLSFKNMCKL+PLL
Sbjct: 50  ELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLL 109

Query: 314 NKWLEETDSSSGSPTNLDKIA-----AQGRKRKKRTSIEVGVKGALESHFLKCPKPSAHE 368
            KW+EE D++     NL +I       Q RKR KRTSIE  V+G LE+ FL+CPKP+  +
Sbjct: 110 QKWVEEADNNE----NLQEICKAETLVQARKR-KRTSIENRVRGNLENLFLQCPKPTLQQ 164

Query: 369 ITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPGGGGASPPS 428
           I+ +A  L LEK+VVRVWFCNRRQK KR    + + +   +D  A G     GG  S P 
Sbjct: 165 ISHIAQQLGLEKDVVRVWFCNRRQKGKR----SSSDYAQREDFEAAGS-PFSGGPVSFPL 219

Query: 429 APPP 432
           AP P
Sbjct: 220 APGP 223


>gi|170650730 pituitary specific transcription factor 1 isoform beta
           [Homo sapiens]
          Length = 317

 Score =  181 bits (459), Expect = 1e-45
 Identities = 100/193 (51%), Positives = 125/193 (64%), Gaps = 2/193 (1%)

Query: 205 PPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSSDDLEQFAKQFKQ 264
           P H  +HG    H         AA            V E  D D+P   +LE+FA +FK 
Sbjct: 108 PDHTLSHGFPPIHQPLLAEDPTAADFKQELRRKSKLVEEPIDMDSPEIRELEKFANEFKV 167

Query: 265 RRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEETDSSS 324
           RRIKLG+TQ +VG AL  ++G+ FSQTTICRFE LQLSFKN CKLK +L+KWLEE +   
Sbjct: 168 RRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAE-QV 226

Query: 325 GSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVR 384
           G+  N +K+ A  RKRK+RT+I +  K ALE HF +  KPS+ EI  +A+ L LEKEVVR
Sbjct: 227 GALYN-EKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVR 285

Query: 385 VWFCNRRQKEKRM 397
           VWFCNRRQ+EKR+
Sbjct: 286 VWFCNRRQREKRV 298


>gi|4505955 pituitary specific transcription factor 1 isoform alpha
           [Homo sapiens]
          Length = 291

 Score =  181 bits (459), Expect = 1e-45
 Identities = 100/193 (51%), Positives = 125/193 (64%), Gaps = 2/193 (1%)

Query: 205 PPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSSDDLEQFAKQFKQ 264
           P H  +HG    H         AA            V E  D D+P   +LE+FA +FK 
Sbjct: 82  PDHTLSHGFPPIHQPLLAEDPTAADFKQELRRKSKLVEEPIDMDSPEIRELEKFANEFKV 141

Query: 265 RRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEETDSSS 324
           RRIKLG+TQ +VG AL  ++G+ FSQTTICRFE LQLSFKN CKLK +L+KWLEE +   
Sbjct: 142 RRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAE-QV 200

Query: 325 GSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVR 384
           G+  N +K+ A  RKRK+RT+I +  K ALE HF +  KPS+ EI  +A+ L LEKEVVR
Sbjct: 201 GALYN-EKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVR 259

Query: 385 VWFCNRRQKEKRM 397
           VWFCNRRQ+EKR+
Sbjct: 260 VWFCNRRQREKRV 272


>gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]
          Length = 409

 Score =  169 bits (428), Expect = 5e-42
 Identities = 146/411 (35%), Positives = 190/411 (46%), Gaps = 67/411 (16%)

Query: 41  HAGAAYREVQ-KLMHHEWLGAGAGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGG 99
           H G+ + E +   +H    G+ A      + P      GGGGG   GG         GGG
Sbjct: 16  HGGSLHVEPKYSALHSTSPGSSAPIAPSASSPSSSSNAGGGGGGGGGG---------GGG 66

Query: 100 TGRADD-------GGGG-----------------GGFHARLVHQGAAHAGA-AWAQGSTA 134
            GR+         GGGG                 GG    L+ +  A A     +Q  + 
Sbjct: 67  GGRSSSSSSSGSSGGGGSEAMRRACLPTPPSNIFGGLDESLLARAEALAAVDIVSQSKSH 126

Query: 135 HHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHED 194
           HH  P  SP    +  H    +   + A+        ++   A  G       HH  H  
Sbjct: 127 HHHPPHHSPFKPDATYHTMNTIPCTSAAS---SSSVPISHPSALAGTHHHHHHHHHHHHQ 183

Query: 195 GHEAQ----LEP-SPPPHLGAHG-----------HAHGHAHAGGLHAAA---AHLHPGAG 235
            H+A     LE  SP   LGA             HA   A    +H AA   AH H    
Sbjct: 184 PHQALEGELLEHLSPGLALGAMAGPDGAVVSTPAHAPHMATMNPMHQAALSMAHAH---- 239

Query: 236 GGGSSVGEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTL----YGNVFSQT 291
           G  S +G  SD DA   D LE FA++FKQRRIKLG TQADVG AL  L     G++ SQ+
Sbjct: 240 GLPSHMGCMSDVDADPRD-LEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSL-SQS 297

Query: 292 TICRFEALQLSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVK 351
           TICRFE+L LS  NM  LKP+L  WLEE + S        ++     K++KRTSI    K
Sbjct: 298 TICRFESLTLSHNNMIALKPILQAWLEEAEKSHREKLTKPELFNGAEKKRKRTSIAAPEK 357

Query: 352 GALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAG 402
            +LE++F   P+PS+ +I  +A+ L L+K VVRVWFCN+RQK+KRM  +AG
Sbjct: 358 RSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKYSAG 408



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 4/111 (3%)

Query: 337 GRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKR 396
           GR     +S   G  G+        P P ++   GL +SL    E +       + K   
Sbjct: 68  GRSSSSSSSGSSGGGGSEAMRRACLPTPPSNIFGGLDESLLARAEALAAVDIVSQSKSHH 127

Query: 397 MTPAAGAGHPPMDDVYAPGELGPGGGGASPPSAPPPPPPAAL---HHHHHH 444
             P   +   P D  Y      P    AS  S P   P A     HHHHHH
Sbjct: 128 HHPPHHSPFKP-DATYHTMNTIPCTSAASSSSVPISHPSALAGTHHHHHHH 177


>gi|4505965 POU class 4 homeobox 3 [Homo sapiens]
          Length = 338

 Score =  155 bits (393), Expect = 5e-38
 Identities = 100/237 (42%), Positives = 132/237 (55%), Gaps = 31/237 (13%)

Query: 188 HHALHEDGHEAQLEPSPPPHLGAHG-------------HAHGHAHAGGLHAAAAHLHPGA 234
           HHA+H+ G E  L     P L   G             H H     G LH A    HP  
Sbjct: 108 HHAVHQ-GLEGDLLEHISPTLSVSGLGAPEHSVMPAQIHPHHLGAMGHLHQAMGMSHP-- 164

Query: 235 GGGGSSVGEHSDEDAPSSD------DLEQFAKQFKQRRIKLGFTQADVGLALGTL----Y 284
                +V  HS   A  SD      +LE FA++FKQRRIKLG TQADVG AL  L     
Sbjct: 165 ----HTVAPHSAMPACLSDVESDPRELEAFAERFKQRRIKLGVTQADVGAALANLKIPGV 220

Query: 285 GNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRT 344
           G++ SQ+TICRFE+L LS  NM  LKP+L  WLEE +++     +  ++     +++KRT
Sbjct: 221 GSL-SQSTICRFESLTLSHNNMIALKPVLQAWLEEAEAAYREKNSKPELFNGSERKRKRT 279

Query: 345 SIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAA 401
           SI    K +LE++F   P+PS+ +I  +A+ L L+K VVRVWFCN+RQK+KRM  +A
Sbjct: 280 SIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKYSA 336


>gi|23463326 POU domain class 5, transcription factor 2 [Homo
           sapiens]
          Length = 328

 Score =  139 bits (350), Expect = 5e-33
 Identities = 75/167 (44%), Positives = 106/167 (63%), Gaps = 4/167 (2%)

Query: 254 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLL 313
           +L+Q AK+ +Q+R+ LG++QADVG+A+G L+G V SQTTICRFEA QLS  NM KL+PLL
Sbjct: 125 ELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKLRPLL 184

Query: 314 NKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLA 373
            KWL+E ++ +       ++  Q   + +R S E  +  +LE  F +CPKP+  +I+ +A
Sbjct: 185 KKWLKEVEAENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQISHIA 244

Query: 374 DSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPG 420
             LQL+K+VVRVWF NR +   R T  A     P + V   G   PG
Sbjct: 245 GCLQLQKDVVRVWFYNRSKMGSRPTNDAS----PREIVGTAGPPCPG 287


>gi|223890225 POU class 6 homeobox 1 [Homo sapiens]
          Length = 301

 Score =  127 bits (320), Expect = 2e-29
 Identities = 68/153 (44%), Positives = 94/153 (61%), Gaps = 3/153 (1%)

Query: 246 DEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKN 305
           DED  + +++ +FAK FK RR+ LG TQ  VG AL    G  +SQ+ ICRFE L ++ K+
Sbjct: 138 DEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKS 197

Query: 306 MCKLKPLLNKWLEETD--SSSGSPTNLDKIAAQ-GRKRKKRTSIEVGVKGALESHFLKCP 362
             KLKP+L KWL E +  +  G    ++ +  +  +KRK+RTS       AL ++F K P
Sbjct: 198 AQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNP 257

Query: 363 KPSAHEITGLADSLQLEKEVVRVWFCNRRQKEK 395
            P+  EIT +A  L  ++EVVRVWFCNRRQ  K
Sbjct: 258 LPTGQEITEIAKELNYDREVVRVWFCNRRQTLK 290


>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
           sapiens]
          Length = 691

 Score =  101 bits (251), Expect = 2e-21
 Identities = 66/209 (31%), Positives = 99/209 (47%), Gaps = 46/209 (22%)

Query: 248 DAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICR------------ 295
           D  + +++ +FAK FK RR+ LG TQ  VG AL    G  +SQ+ ICR            
Sbjct: 477 DGVNLEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFLPQ 536

Query: 296 ------------------------FEALQLSFKNMCKLKPLLNKWLEETDSS--SGSPTN 329
                                   FE L ++ K+  K+KP+L +W+ E ++   +G    
Sbjct: 537 EAQENTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQNL 596

Query: 330 LDKIAAQ-GRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFC 388
            + I ++  +KRK+RTS        L +HF K   PS  E+T +A+ L  ++EVVRVWFC
Sbjct: 597 TEFIGSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFC 656

Query: 389 NRRQ-------KEKRMTPAAGAGHPPMDD 410
           N+RQ       + K+  PA      P+ D
Sbjct: 657 NKRQALKNTIKRLKQHEPATAVPLEPLTD 685


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 67/224 (29%), Positives = 84/224 (37%), Gaps = 48/224 (21%)

Query: 11  GPGGGAG------------GTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWL 58
           GPGG AG            G G +MH  +AAAA A  + + L             H  + 
Sbjct: 185 GPGGRAGPCFDQHGGQQSPGMG-MMHSASAAAAGAPGSMDPLQNS----------HEGYP 233

Query: 59  GAGAGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVH 118
            +   H  G + P     GGGGGG   GG     G  GGGG G A  GG G G  A    
Sbjct: 234 NSQCNHYPGYSRPG---AGGGGGGGGGGGG----GSGGGGGGGGAGAGGAGAGAVAAAAA 286

Query: 119 QGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAA 178
             AA AG     G      G  +  SP   GG               G GGGG A +  A
Sbjct: 287 AAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGG-----------GMMMGPGGGGAASLSKA 335

Query: 179 GGGGAGPGLHHALHEDGHEA-------QLEPSPPPHLGAHGHAH 215
             G A  G      ++ H +       QL  SP P + ++G ++
Sbjct: 336 AAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSY 379



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 75/248 (30%), Positives = 88/248 (35%), Gaps = 55/248 (22%)

Query: 11  GPGGGAGGTGPLMHP-------DAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGAGAG 63
           G GGGA   GP M         D+AA   A      L +     +       E  G    
Sbjct: 84  GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYE 143

Query: 64  HP----VGLAHPQWLPTGGGGGGDWAGGPHLEH-----GKAGGGGTGRA----DDGGGGG 110
           HP    +G   P     GGGGG   A  P   +       A GG  GRA    D  GG  
Sbjct: 144 HPGLGALGTQQPPVAVPGGGGGP--AAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQ 201

Query: 111 GFHARLVHQGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGG 170
                ++H  +A A AA A GS        M P   +  G+       Y   + PG GGG
Sbjct: 202 SPGMGMMH--SASAAAAGAPGS--------MDPLQNSHEGYPNSQCNHYPGYSRPGAGGG 251

Query: 171 GLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHL 230
           G  G    GGGG+G G                      G  G   G A AG + AAAA  
Sbjct: 252 GGGG--GGGGGGSGGGG---------------------GGGGAGAGGAGAGAVAAAAAAA 288

Query: 231 HPGAGGGG 238
              AGGGG
Sbjct: 289 AAAAGGGG 296



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 63/239 (26%), Positives = 77/239 (32%), Gaps = 64/239 (26%)

Query: 7   YLPRGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGAGAGHPV 66
           Y   G GGG GG G            +        AGA              GAGAG   
Sbjct: 243 YSRPGAGGGGGGGG-------GGGGGSGGGGGGGGAGAG-------------GAGAGAVA 282

Query: 67  GLAHPQWLPTGGGGGGDWAG--------------GPHLEHGKAGGGGT--GRADDGGGGG 110
             A       GGGGGG + G              G  +  G  GGG     +A  G   G
Sbjct: 283 AAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAG 342

Query: 111 GFHARLVHQGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQ----------PLGLYA 160
           GF  R   Q    +GA      T + L  + SP   + GG  P+          P    +
Sbjct: 343 GFQ-RFAGQNQHPSGAT----PTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQS 397

Query: 161 QAAYPGGGGGGLAGMLAAGGGGAGPGL----------HHALHEDGHEAQLEPSPPPHLG 209
           QAA  G   G   G  AA G G G  +            A  +  H A    +P P +G
Sbjct: 398 QAAAAGAAAG---GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMG 453



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 56/187 (29%), Positives = 64/187 (34%), Gaps = 34/187 (18%)

Query: 77  GGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGSTAHH 136
           GG GGG    GP +E  + GG     A  GG        L+ +      A    G  A  
Sbjct: 83  GGAGGGAPQPGPDMEQPQHGGAKDSAA--GGQADPPGPPLLSKPGDEDDAPPKMGEPAG- 139

Query: 137 LGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLA--------GMLAAGGGGAGPGLH 188
            G    P  GA G  QP         A PGGGGG  A        G  A   G  GPG  
Sbjct: 140 -GRYEHPGLGALGTQQP-------PVAVPGGGGGPAAVPEFNNYYGSAAPASG--GPGGR 189

Query: 189 HALHEDGHEAQLEPSPPPHLGAHGHAHG---------HAHAGGLHAAAAHL----HPGAG 235
                D H  Q  P       A   A G         ++H G  ++   H      PGAG
Sbjct: 190 AGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAG 249

Query: 236 GGGSSVG 242
           GGG   G
Sbjct: 250 GGGGGGG 256



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 14/30 (46%), Positives = 15/30 (50%), Gaps = 4/30 (13%)

Query: 202 PSPPPHLGAHGHAHGHAHAGGLHAAAAHLH 231
           P+ PPH   H H H H H    H  A HLH
Sbjct: 18  PAAPPHQQHHHHHHAHHH----HHHAHHLH 43



 Score = 30.0 bits (66), Expect = 4.5
 Identities = 24/85 (28%), Positives = 29/85 (34%), Gaps = 9/85 (10%)

Query: 161 QAAYPGGGGGGLAGMLAAGGGGAGPG------LHHALHEDGHEAQLEPSPPPHLGAHGHA 214
           Q  +P      L G   AGGG   PG       H    +     Q +P  PP L   G  
Sbjct: 71  QQQHPISNNNSLGG---AGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDE 127

Query: 215 HGHAHAGGLHAAAAHLHPGAGGGGS 239
                  G  A   + HPG G  G+
Sbjct: 128 DDAPPKMGEPAGGRYEHPGLGALGT 152


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 67/224 (29%), Positives = 84/224 (37%), Gaps = 48/224 (21%)

Query: 11  GPGGGAG------------GTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWL 58
           GPGG AG            G G +MH  +AAAA A  + + L             H  + 
Sbjct: 185 GPGGRAGPCFDQHGGQQSPGMG-MMHSASAAAAGAPGSMDPLQNS----------HEGYP 233

Query: 59  GAGAGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVH 118
            +   H  G + P     GGGGGG   GG     G  GGGG G A  GG G G  A    
Sbjct: 234 NSQCNHYPGYSRPG---AGGGGGGGGGGGG----GSGGGGGGGGAGAGGAGAGAVAAAAA 286

Query: 119 QGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAA 178
             AA AG     G      G  +  SP   GG               G GGGG A +  A
Sbjct: 287 AAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGG-----------GMMMGPGGGGAASLSKA 335

Query: 179 GGGGAGPGLHHALHEDGHEA-------QLEPSPPPHLGAHGHAH 215
             G A  G      ++ H +       QL  SP P + ++G ++
Sbjct: 336 AAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSY 379



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 75/248 (30%), Positives = 88/248 (35%), Gaps = 55/248 (22%)

Query: 11  GPGGGAGGTGPLMHP-------DAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGAGAG 63
           G GGGA   GP M         D+AA   A      L +     +       E  G    
Sbjct: 84  GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYE 143

Query: 64  HP----VGLAHPQWLPTGGGGGGDWAGGPHLEH-----GKAGGGGTGRA----DDGGGGG 110
           HP    +G   P     GGGGG   A  P   +       A GG  GRA    D  GG  
Sbjct: 144 HPGLGALGTQQPPVAVPGGGGGP--AAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQ 201

Query: 111 GFHARLVHQGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGG 170
                ++H  +A A AA A GS        M P   +  G+       Y   + PG GGG
Sbjct: 202 SPGMGMMH--SASAAAAGAPGS--------MDPLQNSHEGYPNSQCNHYPGYSRPGAGGG 251

Query: 171 GLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHL 230
           G  G    GGGG+G G                      G  G   G A AG + AAAA  
Sbjct: 252 GGGG--GGGGGGSGGGG---------------------GGGGAGAGGAGAGAVAAAAAAA 288

Query: 231 HPGAGGGG 238
              AGGGG
Sbjct: 289 AAAAGGGG 296



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 63/239 (26%), Positives = 77/239 (32%), Gaps = 64/239 (26%)

Query: 7   YLPRGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGAGAGHPV 66
           Y   G GGG GG G            +        AGA              GAGAG   
Sbjct: 243 YSRPGAGGGGGGGG-------GGGGGSGGGGGGGGAGAG-------------GAGAGAVA 282

Query: 67  GLAHPQWLPTGGGGGGDWAG--------------GPHLEHGKAGGGGT--GRADDGGGGG 110
             A       GGGGGG + G              G  +  G  GGG     +A  G   G
Sbjct: 283 AAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAG 342

Query: 111 GFHARLVHQGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQ----------PLGLYA 160
           GF  R   Q    +GA      T + L  + SP   + GG  P+          P    +
Sbjct: 343 GFQ-RFAGQNQHPSGAT----PTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQS 397

Query: 161 QAAYPGGGGGGLAGMLAAGGGGAGPGL----------HHALHEDGHEAQLEPSPPPHLG 209
           QAA  G   G   G  AA G G G  +            A  +  H A    +P P +G
Sbjct: 398 QAAAAGAAAG---GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMG 453



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 56/187 (29%), Positives = 64/187 (34%), Gaps = 34/187 (18%)

Query: 77  GGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGSTAHH 136
           GG GGG    GP +E  + GG     A  GG        L+ +      A    G  A  
Sbjct: 83  GGAGGGAPQPGPDMEQPQHGGAKDSAA--GGQADPPGPPLLSKPGDEDDAPPKMGEPAG- 139

Query: 137 LGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLA--------GMLAAGGGGAGPGLH 188
            G    P  GA G  QP         A PGGGGG  A        G  A   G  GPG  
Sbjct: 140 -GRYEHPGLGALGTQQP-------PVAVPGGGGGPAAVPEFNNYYGSAAPASG--GPGGR 189

Query: 189 HALHEDGHEAQLEPSPPPHLGAHGHAHG---------HAHAGGLHAAAAHL----HPGAG 235
                D H  Q  P       A   A G         ++H G  ++   H      PGAG
Sbjct: 190 AGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAG 249

Query: 236 GGGSSVG 242
           GGG   G
Sbjct: 250 GGGGGGG 256



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 14/30 (46%), Positives = 15/30 (50%), Gaps = 4/30 (13%)

Query: 202 PSPPPHLGAHGHAHGHAHAGGLHAAAAHLH 231
           P+ PPH   H H H H H    H  A HLH
Sbjct: 18  PAAPPHQQHHHHHHAHHH----HHHAHHLH 43



 Score = 30.0 bits (66), Expect = 4.5
 Identities = 24/85 (28%), Positives = 29/85 (34%), Gaps = 9/85 (10%)

Query: 161 QAAYPGGGGGGLAGMLAAGGGGAGPG------LHHALHEDGHEAQLEPSPPPHLGAHGHA 214
           Q  +P      L G   AGGG   PG       H    +     Q +P  PP L   G  
Sbjct: 71  QQQHPISNNNSLGG---AGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDE 127

Query: 215 HGHAHAGGLHAAAAHLHPGAGGGGS 239
                  G  A   + HPG G  G+
Sbjct: 128 DDAPPKMGEPAGGRYEHPGLGALGT 152


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 67/224 (29%), Positives = 84/224 (37%), Gaps = 48/224 (21%)

Query: 11  GPGGGAG------------GTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWL 58
           GPGG AG            G G +MH  +AAAA A  + + L             H  + 
Sbjct: 185 GPGGRAGPCFDQHGGQQSPGMG-MMHSASAAAAGAPGSMDPLQNS----------HEGYP 233

Query: 59  GAGAGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVH 118
            +   H  G + P     GGGGGG   GG     G  GGGG G A  GG G G  A    
Sbjct: 234 NSQCNHYPGYSRPG---AGGGGGGGGGGGG----GSGGGGGGGGAGAGGAGAGAVAAAAA 286

Query: 119 QGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAA 178
             AA AG     G      G  +  SP   GG               G GGGG A +  A
Sbjct: 287 AAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGG-----------GMMMGPGGGGAASLSKA 335

Query: 179 GGGGAGPGLHHALHEDGHEA-------QLEPSPPPHLGAHGHAH 215
             G A  G      ++ H +       QL  SP P + ++G ++
Sbjct: 336 AAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSY 379



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 75/248 (30%), Positives = 88/248 (35%), Gaps = 55/248 (22%)

Query: 11  GPGGGAGGTGPLMHP-------DAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGAGAG 63
           G GGGA   GP M         D+AA   A      L +     +       E  G    
Sbjct: 84  GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYE 143

Query: 64  HP----VGLAHPQWLPTGGGGGGDWAGGPHLEH-----GKAGGGGTGRA----DDGGGGG 110
           HP    +G   P     GGGGG   A  P   +       A GG  GRA    D  GG  
Sbjct: 144 HPGLGALGTQQPPVAVPGGGGGP--AAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQ 201

Query: 111 GFHARLVHQGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGG 170
                ++H  +A A AA A GS        M P   +  G+       Y   + PG GGG
Sbjct: 202 SPGMGMMH--SASAAAAGAPGS--------MDPLQNSHEGYPNSQCNHYPGYSRPGAGGG 251

Query: 171 GLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHL 230
           G  G    GGGG+G G                      G  G   G A AG + AAAA  
Sbjct: 252 GGGG--GGGGGGSGGGG---------------------GGGGAGAGGAGAGAVAAAAAAA 288

Query: 231 HPGAGGGG 238
              AGGGG
Sbjct: 289 AAAAGGGG 296



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 63/239 (26%), Positives = 77/239 (32%), Gaps = 64/239 (26%)

Query: 7   YLPRGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGAGAGHPV 66
           Y   G GGG GG G            +        AGA              GAGAG   
Sbjct: 243 YSRPGAGGGGGGGG-------GGGGGSGGGGGGGGAGAG-------------GAGAGAVA 282

Query: 67  GLAHPQWLPTGGGGGGDWAG--------------GPHLEHGKAGGGGT--GRADDGGGGG 110
             A       GGGGGG + G              G  +  G  GGG     +A  G   G
Sbjct: 283 AAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAG 342

Query: 111 GFHARLVHQGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQ----------PLGLYA 160
           GF  R   Q    +GA      T + L  + SP   + GG  P+          P    +
Sbjct: 343 GFQ-RFAGQNQHPSGAT----PTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQS 397

Query: 161 QAAYPGGGGGGLAGMLAAGGGGAGPGL----------HHALHEDGHEAQLEPSPPPHLG 209
           QAA  G   G   G  AA G G G  +            A  +  H A    +P P +G
Sbjct: 398 QAAAAGAAAG---GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMG 453



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 56/187 (29%), Positives = 64/187 (34%), Gaps = 34/187 (18%)

Query: 77  GGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGSTAHH 136
           GG GGG    GP +E  + GG     A  GG        L+ +      A    G  A  
Sbjct: 83  GGAGGGAPQPGPDMEQPQHGGAKDSAA--GGQADPPGPPLLSKPGDEDDAPPKMGEPAG- 139

Query: 137 LGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLA--------GMLAAGGGGAGPGLH 188
            G    P  GA G  QP         A PGGGGG  A        G  A   G  GPG  
Sbjct: 140 -GRYEHPGLGALGTQQP-------PVAVPGGGGGPAAVPEFNNYYGSAAPASG--GPGGR 189

Query: 189 HALHEDGHEAQLEPSPPPHLGAHGHAHG---------HAHAGGLHAAAAHL----HPGAG 235
                D H  Q  P       A   A G         ++H G  ++   H      PGAG
Sbjct: 190 AGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAG 249

Query: 236 GGGSSVG 242
           GGG   G
Sbjct: 250 GGGGGGG 256



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 14/30 (46%), Positives = 15/30 (50%), Gaps = 4/30 (13%)

Query: 202 PSPPPHLGAHGHAHGHAHAGGLHAAAAHLH 231
           P+ PPH   H H H H H    H  A HLH
Sbjct: 18  PAAPPHQQHHHHHHAHHH----HHHAHHLH 43



 Score = 30.0 bits (66), Expect = 4.5
 Identities = 24/85 (28%), Positives = 29/85 (34%), Gaps = 9/85 (10%)

Query: 161 QAAYPGGGGGGLAGMLAAGGGGAGPG------LHHALHEDGHEAQLEPSPPPHLGAHGHA 214
           Q  +P      L G   AGGG   PG       H    +     Q +P  PP L   G  
Sbjct: 71  QQQHPISNNNSLGG---AGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDE 127

Query: 215 HGHAHAGGLHAAAAHLHPGAGGGGS 239
                  G  A   + HPG G  G+
Sbjct: 128 DDAPPKMGEPAGGRYEHPGLGALGT 152


>gi|89257348 homeo box HB9 [Homo sapiens]
          Length = 401

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 103/378 (27%), Positives = 125/378 (33%), Gaps = 113/378 (29%)

Query: 95  AGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGSTAHHLGPAMSPSPGASG----G 150
           A   GTG    GGGGGG                 A G T+    PA S  P A       
Sbjct: 36  AAASGTG---GGGGGGG-----------------ASGGTSGSCSPASSEPPAAPADRLRA 75

Query: 151 HQPQPLGLYAQ--AAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHL 208
             P P  L A   A  P        G L AGGGG G G                      
Sbjct: 76  ESPSPPRLLAAHCALLPK------PGFLGAGGGGGGTG---------------------- 107

Query: 209 GAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSSDDLEQFAKQFKQRRIK 268
           G HG  H HAH G   AAAA     A  GG ++G H                        
Sbjct: 108 GGHGGPHHHAHPGAAAAAAAAA-AAAAAGGLALGLHP----------------------- 143

Query: 269 LGFTQADVGL-ALGTLYGN-VFSQTTIC-------RFEALQLSFKNMCKLKPL------- 312
            G  Q   GL A   LYG+ V+  +          +  AL  S+  +    P        
Sbjct: 144 -GGAQGGAGLPAQAALYGHPVYGYSAAAAAAALAGQHPALSYSYPQVQGAHPAHPADPIK 202

Query: 313 -------LNKWLEETDSSSGSPTNLD-KIAAQ----GRKRKKRTSIEVGVKGALESHFLK 360
                  L++WL  + +    P   D    AQ    G+ R+ RT+        LE  F  
Sbjct: 203 LGAGTFQLDQWLRASTAGMILPKMPDFNSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKL 262

Query: 361 CPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPG 420
               S  +   +A SL L +  V++WF NRR K KR   A        +     G  G G
Sbjct: 263 NKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKEQAAQEAEKQKGGGG-GAG 321

Query: 421 GGGASPPSA-----PPPP 433
            GGA  P A     PP P
Sbjct: 322 KGGAEEPGAEELLGPPAP 339



 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 60/200 (30%), Positives = 74/200 (37%), Gaps = 40/200 (20%)

Query: 11  GPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGAGAGHPVGLAH 70
           G GG +GGT     P  A++   AA A+RL A +      +L+        A H   L  
Sbjct: 46  GGGGASGGTSGSCSP--ASSEPPAAPADRLRAESP--SPPRLL--------AAHCALLPK 93

Query: 71  PQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQ 130
           P +L  GGGGGG                       GGG GG H    H GAA A AA A 
Sbjct: 94  PGFLGAGGGGGGT----------------------GGGHGGPHHH-AHPGAAAAAAAAAA 130

Query: 131 GSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHA 190
            + A  L   + P     G   P    LY    Y     G  A   AA   G  P L ++
Sbjct: 131 AAAAGGLALGLHPGGAQGGAGLPAQAALYGHPVY-----GYSAAAAAAALAGQHPALSYS 185

Query: 191 LHEDGHEAQLEPSPPPHLGA 210
             +        P+ P  LGA
Sbjct: 186 YPQVQGAHPAHPADPIKLGA 205


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 68/241 (28%), Positives = 73/241 (30%), Gaps = 59/241 (24%)

Query: 10  RGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGAGAGHPVGLA 69
           RG  GG  G GP                 R H G          H    G G G  +G  
Sbjct: 723 RGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGG--MGSG 780

Query: 70  HPQWLPTGGGGGGDWAGGPHLEHGKAGGG---GTGRADDGGGGGGFHARLVHQGAAHAGA 126
           H    P  G GG    GG H  H   GGG   G+G     G GGG               
Sbjct: 781 HR---PHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGM-------------- 823

Query: 127 AWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLA-AGGGGAGP 185
                              GA GGH+P           PGG  GG  G     G G  GP
Sbjct: 824 -------------------GAGGGHRPH--------EGPGGSMGGSGGHRPHEGPGHGGP 856

Query: 186 GLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHS 245
             H      GH       PPPH   H    G  H GG H        G  GG S  G+ S
Sbjct: 857 HGHRPHDVPGHRGHDHRGPPPH--EHRGHDGPGHGGGGHR-------GHDGGHSHGGDMS 907

Query: 246 D 246
           +
Sbjct: 908 N 908



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 73/280 (26%), Positives = 95/280 (33%), Gaps = 53/280 (18%)

Query: 9   PRGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREV--QKLMHHEWLGAGAGHPV 66
           P+GPGGG      ++   +   +  +  +E L     Y +   Q L+ H  LG G   P+
Sbjct: 571 PQGPGGGGINVQEIL--TSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPG---PI 625

Query: 67  GLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAHAGA 126
                   P GG GG        ++H   G GG      GG GG    RL+       G 
Sbjct: 626 A----NGFPPGGPGGPKG-----MQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGG 676

Query: 127 AWAQGSTAHHL-------GPAMSPSP-----GASGGHQPQP--------LGLYAQAAYPG 166
                     +       GP   P P     G  GG++P P         G  +    P 
Sbjct: 677 DPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPN 736

Query: 167 GGGGGLAGMLAAG--------GGGAGPGLHHALHE-------DGHEAQLEPSPPPHLGAH 211
           G GG   GM+  G        GGG G    H  HE        GH     P      G  
Sbjct: 737 GRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMG-GGG 795

Query: 212 GHAHGHAHAGGLHAAAAHL-HPGAGGGGSSVGEHSDEDAP 250
           GH       GG+   + H  H G GGG  + G H   + P
Sbjct: 796 GHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGP 835



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 72/258 (27%), Positives = 83/258 (32%), Gaps = 46/258 (17%)

Query: 6   QYLPRGPGGGA----GGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGAG 61
           Q+ P GPGG      GG G  + P            +    G         M    +  G
Sbjct: 641 QHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPG-----DPMRGGPMRGG 695

Query: 62  AGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGG---GG--TGRADDGGG--GGGFHA 114
            G   G   P     GG GG +    P    G  GG   GG   GR   GGG  GGG H 
Sbjct: 696 PGPGPG---PYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHR 752

Query: 115 RLVHQGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGG--GGGGL 172
                   H G     G+++ H  P   P  G   GH+P           PGG  GGGG 
Sbjct: 753 -------PHEGPGGGMGNSSGHR-PHEGPGGGMGSGHRPHE--------GPGGSMGGGGG 796

Query: 173 AGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHP 232
                  GGG   G  H  HE          P   +GA G    H   GG    +    P
Sbjct: 797 HRPHEGPGGGISGGSGHRPHE---------GPGGGMGAGGGHRPHEGPGGSMGGSGGHRP 847

Query: 233 GAGGGGSSVGEHSDEDAP 250
             G G      H   D P
Sbjct: 848 HEGPGHGGPHGHRPHDVP 865



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 61/235 (25%), Positives = 71/235 (30%), Gaps = 59/235 (25%)

Query: 75  PTGGGGGGDWAGG---PHLEHGKAGGGGTGRADDGGGGGGFHAR---------------- 115
           P G GG  D AGG   P +     G  G G+   G GGGG + +                
Sbjct: 539 PGGSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSHPSE 598

Query: 116 ---------------LVHQGAAHAGAAWAQGSTAHHLGP-AMSPSPGASGGHQPQPLG-- 157
                          LV  G    G            GP  M   P   GG  P P G  
Sbjct: 599 ELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPHGGP 658

Query: 158 -------LYAQAAYPGGG-------GGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPS 203
                  L      P GG       G  + G    GG G GPG +H         +  P 
Sbjct: 659 GGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPP 718

Query: 204 PPPHLGAHGHAHG-------HAHAGGLHAAAAHL-HPGAGGGGSSVGEHSDEDAP 250
           PPP  GA G   G           GG+     H  H G GGG  +   H   + P
Sbjct: 719 PPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGP 773


>gi|40288197 GATA binding protein 6 [Homo sapiens]
          Length = 595

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 73/231 (31%), Positives = 89/231 (38%), Gaps = 60/231 (25%)

Query: 3   TTAQYLPRGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLM-----HHEW 57
           T A    +GP    G  G  +H  AAAAAAAAAA+  ++       V  ++     H + 
Sbjct: 150 TLAALSSQGPAAYDGAPGGFVHSAAAAAAAAAAASSPVYVPTT--RVGSMLPGLPYHLQG 207

Query: 58  LGAG-AGHPVGL-AHPQW-------LPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGG 108
            G+G A H  G  AHP W        P G GGG   AGG     G AG GG G A     
Sbjct: 208 SGSGPANHAGGAGAHPGWPQASADSPPYGSGGGA--AGG-----GAAGPGGAGSA----- 255

Query: 109 GGGFHARLVHQGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGG 168
                       AAH  A +             SPSP  + G   +P G  A  +   GG
Sbjct: 256 ------------AAHVSARF-----------PYSPSPPMANGAAREPGGYAAAGSGGAGG 292

Query: 169 GGGLAGMLAAGGG--------GAGPGLHHALHEDGHEAQLEPSP-PPHLGA 210
             G    LAA GG         A   L+   H   H     PSP  P++GA
Sbjct: 293 VSGGGSSLAAMGGREPQYSSLSAARPLNGTYHHHHHHHHHHPSPYSPYVGA 343



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 77/283 (27%), Positives = 91/283 (32%), Gaps = 85/283 (30%)

Query: 10  RGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGAGAGHPVGLA 69
           RGPGG +    P +  +AAA   A +                      L + A HP G  
Sbjct: 52  RGPGGASNCGTPQLDTEAAAGPPARSLL--------------------LSSYASHPFGAP 91

Query: 70  HPQWLPTGGGGGGD-----------------------WAGG------------PHLEHGK 94
           H    P   G GG+                       W+                +    
Sbjct: 92  HGPSAPGVAGPGGNLSSWEDLLLFTDLDQAATASKLLWSSRGAKLSPFAPEQPEEMYQTL 151

Query: 95  AGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGSTAH---------------HLGP 139
           A     G A   G  GGF    VH  AA A AA A  S  +               HL  
Sbjct: 152 AALSSQGPAAYDGAPGGF----VHSAAAAAAAAAAASSPVYVPTTRVGSMLPGLPYHLQG 207

Query: 140 AMSPSPGASGGHQPQPLGLYAQA-AYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEA 198
           + S     +GG    P    A A + P G GGG AG  AAG GGAG    H         
Sbjct: 208 SGSGPANHAGGAGAHPGWPQASADSPPYGSGGGAAGGGAAGPGGAGSAAAHV----SARF 263

Query: 199 QLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSV 241
              PSPP   GA     G+A AG   A       G  GGGSS+
Sbjct: 264 PYSPSPPMANGAAREPGGYAAAGSGGAG------GVSGGGSSL 300


>gi|71274111 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           A [Homo sapiens]
          Length = 353

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 73/242 (30%), Positives = 95/242 (39%), Gaps = 53/242 (21%)

Query: 75  PTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGSTA 134
           P  GGGGG   GG   + G A G  +G     GG  G          A     W  G   
Sbjct: 73  PGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSG--------KPALEDLYWMSGYQ- 123

Query: 135 HHLGP-AMSPSPGAS------GGHQPQPLGLY---AQAAYPGGGGGGLAGMLAAGGGGA- 183
           HHL P A++ +P  +       GH     G +   A AAY    G G AG     GGGA 
Sbjct: 124 HHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAG-----GGGAD 178

Query: 184 --GPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSV 241
             G G HH  H   H          H  AH H H H H           H GAG GG + 
Sbjct: 179 DMGAGHHHGAHHAAHH---------HHAAHHHHHHHHH-----------HGGAGHGGGAG 218

Query: 242 GEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADV---GLALGTLYGNVFSQTTICRFEA 298
                E+  S D L   + +   R+++ GF++ +V        TL    ++Q+  CRF+ 
Sbjct: 219 HHVRLEERFSDDQLVSMSVRELNRQLR-GFSKEEVIRLKQKRRTLKNRGYAQS--CRFKR 275

Query: 299 LQ 300
           +Q
Sbjct: 276 VQ 277



 Score = 37.4 bits (85), Expect = 0.028
 Identities = 49/159 (30%), Positives = 57/159 (35%), Gaps = 33/159 (20%)

Query: 11  GPGGGAGGTG-----------PLMHPDAAAAAAAAAAAERLHAGAAYR-----EVQKLMH 54
           G GGGAGG G           P   P A    +   A E L+  + Y+     E   L  
Sbjct: 76  GGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLYWMSGYQHHLNPEALNLTP 135

Query: 55  HEWLGA--GAGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGF 112
            + + A  G+GH  G  H    P        + G      G AGGGG   ADD G G   
Sbjct: 136 EDAVEALIGSGHH-GAHHGAHHPAAAAAYEAFRG-----PGFAGGGG---ADDMGAG--- 183

Query: 113 HARLVHQGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGH 151
           H    H  A H  AA       HH G A     G   GH
Sbjct: 184 HHHGAHHAAHHHHAAHHHHHHHHHHGGA---GHGGGAGH 219


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 42/122 (34%), Positives = 52/122 (42%), Gaps = 15/122 (12%)

Query: 77  GGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGSTAHH 136
           GG GGG + GG        GGG +G    GGG GG H      G  + G +   GS+   
Sbjct: 462 GGRGGGSFGGG-------YGGGSSGGGSSGGGHGGGHGG--SSGGGYGGGSSGGGSSGGG 512

Query: 137 LGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGH 196
            G   S     SGGH     G Y   +  GGGGGG  G  + GG  +G G        GH
Sbjct: 513 YGGGSS-----SGGHGGSSSGGYGGGS-SGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGH 566

Query: 197 EA 198
           ++
Sbjct: 567 KS 568



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 40/127 (31%), Positives = 50/127 (39%), Gaps = 10/127 (7%)

Query: 76  TGGGGGGDWAGG----PHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQG 131
           +GGGGGG   GG      L    + G   G    GG  GG  +R    G    G++   G
Sbjct: 16  SGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYG 75

Query: 132 STAHHLGPAMSPSPGAS--GGHQPQPLGLYAQAAYPGGG-GGGLAGMLAAGGGGAGPGLH 188
                 G +   S G+S  GG      G +   ++ GG  GGG  G    GGGG G G  
Sbjct: 76  GLGGFGGGSFRGSYGSSSFGGSYG---GSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFG 132

Query: 189 HALHEDG 195
                DG
Sbjct: 133 GGFGGDG 139



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 2/97 (2%)

Query: 59  GAGAGHPVGLAHPQWLPTGGGGGGDWAGGPHLE-HGKAGGGGTGRADDGGGGGGFHARLV 117
           G G G   G  +      GG  GG + GG     HG +  GG G    GGGGGG+     
Sbjct: 488 GGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGG-S 546

Query: 118 HQGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQ 154
             G + +G  +  GS++     + S S G S    P+
Sbjct: 547 SGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKGPR 583



 Score = 33.5 bits (75), Expect = 0.40
 Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 17/87 (19%)

Query: 158 LYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGH 217
           L  + +  GGG GG +     GGG +G G                S   H G HG + G 
Sbjct: 453 LEGEGSSGGGGRGGGSFGGGYGGGSSGGG---------------SSGGGHGGGHGGSSGG 497

Query: 218 AHAGGLHAAAAHLHPGAGGGGSSVGEH 244
            + GG  ++      G  GGGSS G H
Sbjct: 498 GYGGG--SSGGGSSGGGYGGGSSSGGH 522


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 43/112 (38%), Positives = 46/112 (41%), Gaps = 17/112 (15%)

Query: 77  GGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGSTAHH 136
           GGGG G W GG        GGGG GR   GGGGGG+       G    G  W  G     
Sbjct: 331 GGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWG------GGGGGGGGWGGGGGGGR 384

Query: 137 LGPAMSPSPGASGGHQPQPLGLYAQAAY--PGGGGGGLAGMLAAGGGGAGPG 186
            G       G  GG+  +  G Y    Y  P GGGGG       GGGG G G
Sbjct: 385 GGFQGRGDYGGRGGYGGR--GGYGGRGYGDPYGGGGG-------GGGGGGGG 427



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 46/130 (35%), Positives = 47/130 (36%), Gaps = 38/130 (29%)

Query: 57  WLGAGAGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARL 116
           W G G G   G         GGGG G W GG     G  GGGG G    GGGGGG   R 
Sbjct: 338 WGGGGGGGGRGGGG------GGGGRGGWGGG----GGGWGGGGGGGGGWGGGGGG--GRG 385

Query: 117 VHQGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGML 176
             QG    G     G    +         G  G   P          Y GGGGGG     
Sbjct: 386 GFQGRGDYGGRGGYGGRGGY---------GGRGYGDP----------YGGGGGGG----- 421

Query: 177 AAGGGGAGPG 186
             GGGG G G
Sbjct: 422 --GGGGGGGG 429



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 42/155 (27%), Positives = 50/155 (32%), Gaps = 54/155 (34%)

Query: 88  PHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGSTAHHLGPAMSPSPGA 147
           P  +  + GGGG G    GGGGGG        G    G     G              G 
Sbjct: 323 PPWQKRQEGGGGRGGWGGGGGGGG------RGGGGGGGGRGGWG--------------GG 362

Query: 148 SGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPH 207
            GG               GGGGGG  G    GGGG G          G + +        
Sbjct: 363 GGGW--------------GGGGGGGGGWGGGGGGGRG----------GFQGR-------- 390

Query: 208 LGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVG 242
            G +G   G+   GG +    +  P  GGGG   G
Sbjct: 391 -GDYGGRGGYGGRGG-YGGRGYGDPYGGGGGGGGG 423



 Score = 33.5 bits (75), Expect = 0.40
 Identities = 22/64 (34%), Positives = 25/64 (39%), Gaps = 25/64 (39%)

Query: 77  GGGGGGDWAGGP---------HLEHGKAGG----------------GGTGRADDGGGGGG 111
           GGGGGG W GG            ++G  GG                GG G    GGGGGG
Sbjct: 369 GGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGG 428

Query: 112 FHAR 115
            + R
Sbjct: 429 GYRR 432



 Score = 29.6 bits (65), Expect = 5.8
 Identities = 25/78 (32%), Positives = 27/78 (34%), Gaps = 1/78 (1%)

Query: 166 GGGGGGLAGMLAAGGG-GAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLH 224
           GGGGGG  G    GGG G G G        G   +         G  G   G    GG  
Sbjct: 350 GGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRG 409

Query: 225 AAAAHLHPGAGGGGSSVG 242
               +   G GGGG   G
Sbjct: 410 YGDPYGGGGGGGGGGGGG 427


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 45/142 (31%), Positives = 60/142 (42%), Gaps = 32/142 (22%)

Query: 59  GAGAGHPVGLAHPQWLPTGGGGGGD-------WAGGPHLEHGKAGGGGTGRADDGGGGGG 111
           G G+G  +  ++ ++  +GGGGGG        + GG     G+ GGG  G +  GG GGG
Sbjct: 21  GLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGG 80

Query: 112 FHARLVHQGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGG 171
           F A  +  G    G +   G  +   G   S S G  GG             + GG GGG
Sbjct: 81  FSASSL--GGGFGGGSRGFGGAS---GGGYSSSGGFGGG-------------FGGGSGGG 122

Query: 172 LAGMLAAG-------GGGAGPG 186
             G   +G       GGGAG G
Sbjct: 123 FGGGYGSGFGGFGGFGGGAGGG 144



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 52/170 (30%), Positives = 63/170 (37%), Gaps = 26/170 (15%)

Query: 77  GGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGS-TAH 135
           GG GG    G      G  GGGG+G    GG GGG  +R    G+   G+    GS   +
Sbjct: 479 GGSGGSYGRGSRGGSGGSYGGGGSG----GGYGGGSGSRGGSGGSYGGGSGSGGGSGGGY 534

Query: 136 HLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDG 195
             G     S G+ GGH     G Y   +  GGG GG       GGG    G     H  G
Sbjct: 535 GGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGG-----GYGGGSGSRGGSGGSHGGG 589

Query: 196 HEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHS 245
                           G   G ++ GG  A+ +    G  GGGS    HS
Sbjct: 590 -------------SGFGGESGGSYGGGEEASGS---GGGYGGGSGKSSHS 623



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 36/130 (27%), Positives = 49/130 (37%), Gaps = 16/130 (12%)

Query: 59  GAGAGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVH 118
           G+G+    G ++     +GGG GG + GG     G    GG+G    GG GG +      
Sbjct: 509 GSGSRGGSGGSYGGGSGSGGGSGGGYGGG----SGGGHSGGSGGGHSGGSGGNYGGGSGS 564

Query: 119 QGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAA 178
            G +  G     GS             G SGG      G   ++    GGG   +G    
Sbjct: 565 GGGSGGGYGGGSGSR------------GGSGGSHGGGSGFGGESGGSYGGGEEASGSGGG 612

Query: 179 GGGGAGPGLH 188
            GGG+G   H
Sbjct: 613 YGGGSGKSSH 622



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 38/149 (25%), Positives = 50/149 (33%), Gaps = 19/149 (12%)

Query: 94  KAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQP 153
           ++GGGG G    GG     ++R    G    G  +   S++   G   S   G  GG   
Sbjct: 13  RSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRF---SSSSGYGGGSSRVCGRGGG--- 66

Query: 154 QPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGH 213
              G +   +Y GG GGG +     GG G G          G+ +          G  G 
Sbjct: 67  ---GSFGY-SYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSS---------GGFGG 113

Query: 214 AHGHAHAGGLHAAAAHLHPGAGGGGSSVG 242
             G    GG          G GG G   G
Sbjct: 114 GFGGGSGGGFGGGYGSGFGGFGGFGGGAG 142



 Score = 34.3 bits (77), Expect = 0.24
 Identities = 37/150 (24%), Positives = 52/150 (34%), Gaps = 32/150 (21%)

Query: 4   TAQYLPRGPGGGAGGTGP----LMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLG 59
           ++ YL R  GGG GG G            +++       R  + + Y      +     G
Sbjct: 7   SSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRV----CG 62

Query: 60  AGAGHPVGLAHPQWLPTGGGGGGDWA---------GGPHLEHGKAGGG---------GTG 101
            G G   G ++      GGG GG ++         GG     G +GGG         G G
Sbjct: 63  RGGGGSFGYSY------GGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFG 116

Query: 102 RADDGGGGGGFHARLVHQGAAHAGAAWAQG 131
               GG GGG+ +     G    GA    G
Sbjct: 117 GGSGGGFGGGYGSGFGGFGGFGGGAGGGDG 146



 Score = 30.4 bits (67), Expect = 3.4
 Identities = 17/35 (48%), Positives = 18/35 (51%), Gaps = 3/35 (8%)

Query: 77  GGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGG 111
           GGG GG + GG     G  GG G G    GGG GG
Sbjct: 116 GGGSGGGFGGGYGSGFGGFGGFGGGA---GGGDGG 147


>gi|226437602 NK1 homeobox 2 [Homo sapiens]
          Length = 310

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 39/102 (38%), Positives = 47/102 (46%), Gaps = 1/102 (0%)

Query: 338 RKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRM 397
           + R+ RT+       ALE+ F      S  E   LA SL L +  V++WF NRR K K+ 
Sbjct: 162 KPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQ 221

Query: 398 TPAAGAGHPPMDDVYAPGELGPGGGGASPPSAPPPPPPAALH 439
            P A            PG  G GGGG S  S P PP   ALH
Sbjct: 222 NPGADGAAQVGGGAPQPGAAGGGGGGGSGGS-PGPPGTGALH 262


>gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 39/102 (38%), Positives = 47/102 (46%), Gaps = 1/102 (0%)

Query: 338 RKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRM 397
           + R+ RT+       ALE+ F      S  E   LA SL L +  V++WF NRR K K+ 
Sbjct: 184 KPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQ 243

Query: 398 TPAAGAGHPPMDDVYAPGELGPGGGGASPPSAPPPPPPAALH 439
            P A            PG  G GGGG S  S P PP   ALH
Sbjct: 244 NPGADGAAQVGGGAPQPGAAGGGGGGGSGGS-PGPPGTGALH 284


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.135    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,904,555
Number of Sequences: 37866
Number of extensions: 1780813
Number of successful extensions: 28892
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 554
Number of HSP's successfully gapped in prelim test: 711
Number of HSP's that attempted gapping in prelim test: 14789
Number of HSP's gapped (non-prelim): 8774
length of query: 451
length of database: 18,247,518
effective HSP length: 106
effective length of query: 345
effective length of database: 14,233,722
effective search space: 4910634090
effective search space used: 4910634090
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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