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Search of human proteins with 110611917
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110611917 tetratricopeptide repeat domain 14 isoform b [Homo
sapiens]
(439 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110611917 tetratricopeptide repeat domain 14 isoform b [Homo ... 874 0.0
gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo s... 856 0.0
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 56 7e-08
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 48 2e-05
gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens] 43 6e-04
gi|4503729 FK506 binding protein 52 [Homo sapiens] 42 0.001
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 41 0.002
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 41 0.002
gi|83415184 transmembrane and tetratricopeptide repeat containin... 40 0.003
gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo ... 40 0.004
gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo ... 40 0.004
gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 40 0.005
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 40 0.005
gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Hom... 39 0.009
gi|4759336 Fanconi anemia, complementation group G [Homo sapiens] 39 0.012
gi|56606133 tetratricopeptide repeat domain 32 [Homo sapiens] 39 0.012
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 38 0.016
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 37 0.027
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 37 0.027
gi|31542980 interferon-induced protein with tetratricopeptide re... 37 0.027
gi|72534658 interferon-induced protein with tetratricopeptide re... 37 0.027
gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap... 37 0.036
gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] 37 0.046
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] 37 0.046
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] 37 0.046
gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] 36 0.061
gi|89179321 smooth muscle cell associated protein-1 isoform 3 [H... 36 0.061
gi|29725607 smooth muscle cell associated protein-1 isoform 2 [H... 36 0.061
gi|22749211 transmembrane and tetratricopeptide repeat containin... 36 0.079
gi|27262638 sperm associated antigen 1 [Homo sapiens] 36 0.079
>gi|110611917 tetratricopeptide repeat domain 14 isoform b [Homo
sapiens]
Length = 439
Score = 874 bits (2257), Expect = 0.0
Identities = 439/439 (100%), Positives = 439/439 (100%)
Query: 1 MDRDLLRQSLNCHGSSLLSLLRSEQQDNPHFRSLLGSAAEPARGPPPQHPLQGRKEKRVD 60
MDRDLLRQSLNCHGSSLLSLLRSEQQDNPHFRSLLGSAAEPARGPPPQHPLQGRKEKRVD
Sbjct: 1 MDRDLLRQSLNCHGSSLLSLLRSEQQDNPHFRSLLGSAAEPARGPPPQHPLQGRKEKRVD 60
Query: 61 NIEIQKFISKKADLLFALSWKSDAPATSEINEDSEDHYAIMPPLEQFMEIPSMDRRELFF 120
NIEIQKFISKKADLLFALSWKSDAPATSEINEDSEDHYAIMPPLEQFMEIPSMDRRELFF
Sbjct: 61 NIEIQKFISKKADLLFALSWKSDAPATSEINEDSEDHYAIMPPLEQFMEIPSMDRRELFF 120
Query: 121 RDIERGDIVIGRISSIREFGFFMVLICLGSGIMRDIAHLEITALCPLRDVPSHSNHGDPL 180
RDIERGDIVIGRISSIREFGFFMVLICLGSGIMRDIAHLEITALCPLRDVPSHSNHGDPL
Sbjct: 121 RDIERGDIVIGRISSIREFGFFMVLICLGSGIMRDIAHLEITALCPLRDVPSHSNHGDPL 180
Query: 181 SYYQTGDIIRAGIKDIDRYHEKLAVSLYSSSLPPHLSGIKLGVISSEELPLYYRRSVELN 240
SYYQTGDIIRAGIKDIDRYHEKLAVSLYSSSLPPHLSGIKLGVISSEELPLYYRRSVELN
Sbjct: 181 SYYQTGDIIRAGIKDIDRYHEKLAVSLYSSSLPPHLSGIKLGVISSEELPLYYRRSVELN 240
Query: 241 SNSLESYENVMQSSLGFVNPGVVEFLLEKLGIDESNPPSLMRGLQSKNFSEDDFASALRK 300
SNSLESYENVMQSSLGFVNPGVVEFLLEKLGIDESNPPSLMRGLQSKNFSEDDFASALRK
Sbjct: 241 SNSLESYENVMQSSLGFVNPGVVEFLLEKLGIDESNPPSLMRGLQSKNFSEDDFASALRK 300
Query: 301 KQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKA 360
KQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKA
Sbjct: 301 KQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKA 360
Query: 361 IEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAED 420
IEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAED
Sbjct: 361 IEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAED 420
Query: 421 ALQKLHKYMQVIPYFLLEI 439
ALQKLHKYMQVIPYFLLEI
Sbjct: 421 ALQKLHKYMQVIPYFLLEI 439
>gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo
sapiens]
Length = 770
Score = 856 bits (2212), Expect = 0.0
Identities = 430/430 (100%), Positives = 430/430 (100%)
Query: 1 MDRDLLRQSLNCHGSSLLSLLRSEQQDNPHFRSLLGSAAEPARGPPPQHPLQGRKEKRVD 60
MDRDLLRQSLNCHGSSLLSLLRSEQQDNPHFRSLLGSAAEPARGPPPQHPLQGRKEKRVD
Sbjct: 1 MDRDLLRQSLNCHGSSLLSLLRSEQQDNPHFRSLLGSAAEPARGPPPQHPLQGRKEKRVD 60
Query: 61 NIEIQKFISKKADLLFALSWKSDAPATSEINEDSEDHYAIMPPLEQFMEIPSMDRRELFF 120
NIEIQKFISKKADLLFALSWKSDAPATSEINEDSEDHYAIMPPLEQFMEIPSMDRRELFF
Sbjct: 61 NIEIQKFISKKADLLFALSWKSDAPATSEINEDSEDHYAIMPPLEQFMEIPSMDRRELFF 120
Query: 121 RDIERGDIVIGRISSIREFGFFMVLICLGSGIMRDIAHLEITALCPLRDVPSHSNHGDPL 180
RDIERGDIVIGRISSIREFGFFMVLICLGSGIMRDIAHLEITALCPLRDVPSHSNHGDPL
Sbjct: 121 RDIERGDIVIGRISSIREFGFFMVLICLGSGIMRDIAHLEITALCPLRDVPSHSNHGDPL 180
Query: 181 SYYQTGDIIRAGIKDIDRYHEKLAVSLYSSSLPPHLSGIKLGVISSEELPLYYRRSVELN 240
SYYQTGDIIRAGIKDIDRYHEKLAVSLYSSSLPPHLSGIKLGVISSEELPLYYRRSVELN
Sbjct: 181 SYYQTGDIIRAGIKDIDRYHEKLAVSLYSSSLPPHLSGIKLGVISSEELPLYYRRSVELN 240
Query: 241 SNSLESYENVMQSSLGFVNPGVVEFLLEKLGIDESNPPSLMRGLQSKNFSEDDFASALRK 300
SNSLESYENVMQSSLGFVNPGVVEFLLEKLGIDESNPPSLMRGLQSKNFSEDDFASALRK
Sbjct: 241 SNSLESYENVMQSSLGFVNPGVVEFLLEKLGIDESNPPSLMRGLQSKNFSEDDFASALRK 300
Query: 301 KQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKA 360
KQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKA
Sbjct: 301 KQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKA 360
Query: 361 IEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAED 420
IEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAED
Sbjct: 361 IEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAED 420
Query: 421 ALQKLHKYMQ 430
ALQKLHKYMQ
Sbjct: 421 ALQKLHKYMQ 430
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 55.8 bits (133), Expect = 7e-08
Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 6/138 (4%)
Query: 307 ALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFEL 366
ALK ++G D +K A+ Y+KA E+D N+ + + A+Y KG NK E E
Sbjct: 225 ALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEK 284
Query: 367 ALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDET------FKDAED 420
A+E +R + + + G +EEK+ +A +Y K+LA T + AE
Sbjct: 285 AIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEK 344
Query: 421 ALQKLHKYMQVIPYFLLE 438
L++ + + P LE
Sbjct: 345 ILKEQERLAYINPDLALE 362
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/111 (24%), Positives = 53/111 (47%), Gaps = 7/111 (6%)
Query: 314 GVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPT 373
G + F+ G + AM Y +A++ + ++ + LY+ + + + +F+LAL++C
Sbjct: 367 GNECFQKGDYPQAMKHYTEAIKRNPKDAK-------LYSNRAACYTKLLEFQLALKDCEE 419
Query: 374 HRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQK 424
+ + LE + + A Y+KAL LD + K+A D Q+
Sbjct: 420 CIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGYQR 470
Score = 34.3 bits (77), Expect = 0.23
Identities = 18/44 (40%), Positives = 24/44 (54%)
Query: 320 VGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIED 363
VG DA+ Y++A+++D N R A YA KG KA ED
Sbjct: 17 VGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYED 60
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 48.1 bits (113), Expect = 2e-05
Identities = 50/186 (26%), Positives = 76/186 (40%), Gaps = 21/186 (11%)
Query: 234 RRSVELNSNSLESYENVMQSSLGFVNPGVVEFLLEKLGIDESNPPSLMRGLQSKNFSEDD 293
+ S+E+ LE+ V P + + E + P L ++ SE+D
Sbjct: 29 QESLEVAIQCLETAFGVTVEDSDLALPQTLPEIFEAAATGKEMPQDLRSPARTPP-SEED 87
Query: 294 FASALRKKQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYAT 353
A A R K G + KV A++ Y KA+E++ N R A Y+
Sbjct: 88 SAEAERLKTE----------GNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSK 137
Query: 354 KGSLNKAIEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALD- 412
G+ A++D E A+ P + A + G L K + A +YYKKAL LD
Sbjct: 138 LGNYAGAVQDCERAICIDPAYSKAYGRM-------GLALSSLNKHVEAVAYYKKALELDP 190
Query: 413 --ETFK 416
ET+K
Sbjct: 191 DNETYK 196
>gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens]
Length = 292
Score = 42.7 bits (99), Expect = 6e-04
Identities = 23/73 (31%), Positives = 44/73 (60%), Gaps = 3/73 (4%)
Query: 326 AMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARK---YLC 382
A+N+ +KA++++ + A++ R LY L++A+ED++ LE P+ AR+ L
Sbjct: 174 AINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLP 233
Query: 383 QTLVERGGQLEEE 395
+ + ER +L+EE
Sbjct: 234 KQIEERNERLKEE 246
>gi|4503729 FK506 binding protein 52 [Homo sapiens]
Length = 459
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/109 (27%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Query: 291 EDDFASALRKKQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGAL 350
E F++ +K A + + + + K+ A+ NKALE+D N + L RG
Sbjct: 303 ESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEA 362
Query: 351 YATKGSLNKAIEDFELALENCPTHRNARKYL--CQTLVERGGQLEEEEK 397
+ A DF+ L+ P ++ A+ L CQ + R QL E+K
Sbjct: 363 HLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRR--QLAREKK 409
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 41.2 bits (95), Expect = 0.002
Identities = 70/313 (22%), Positives = 124/313 (39%), Gaps = 46/313 (14%)
Query: 145 LICLGS---GIMRDIAHLEITALCPLRDVPSHSNHGDPLSYYQTGDIIRA-GIKDIDRYH 200
L C+ S +++ + LE C L+ + + N +++ G + A G + +H
Sbjct: 146 LYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFA--VAWSNLGCVFNAQGEIWLAIHH 203
Query: 201 EKLAVSLYSSSLPPHLSGIKLGVISSEELPLYYRRSVELNSNSLESYENVMQSSLGFVNP 260
+ AV+L + L + I LG + E + L + SL V+ +L V
Sbjct: 204 FEKAVTLDPNFLDAY---INLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACV-- 258
Query: 261 GVVEFLLEKLGIDESNPPSLMRGLQSKNFSEDDF---ASALRKKQSASWALKCVKIGVDY 317
E L L ID + R ++ + D + A+AL++K S + A C +
Sbjct: 259 -YYEQGLIDLAID-----TYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRL 312
Query: 318 FKVGRHVDAMNE-----------------YNKALEIDKQNVEALVARGALYATKGSLNKA 360
H D++N Y KALE+ + A ++ +G L +A
Sbjct: 313 CPT--HADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEA 370
Query: 361 IEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAED 420
+ ++ A+ PT +A + G L+E + A Y +A+ ++ F DA
Sbjct: 371 LMHYKEAIRISPTFADAYSNM-------GNTLKEMQDVQGALQCYTRAIQINPAFADAHS 423
Query: 421 ALQKLHKYMQVIP 433
L +HK IP
Sbjct: 424 NLASIHKDSGNIP 436
Score = 32.3 bits (72), Expect = 0.88
Identities = 31/124 (25%), Positives = 50/124 (40%), Gaps = 21/124 (16%)
Query: 326 AMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTL 385
A+ Y +AL + + +Y +G ++ AI+ + A+E P +A L L
Sbjct: 234 AVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANAL 293
Query: 386 VERGGQLEEEEKFLNAESYYKKALALDETFKDA--------------EDALQKLHKYMQV 431
E+G E AE Y AL L T D+ E+A++ K ++V
Sbjct: 294 KEKGSVAE-------AEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEV 346
Query: 432 IPYF 435
P F
Sbjct: 347 FPEF 350
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 41.2 bits (95), Expect = 0.002
Identities = 70/313 (22%), Positives = 124/313 (39%), Gaps = 46/313 (14%)
Query: 145 LICLGS---GIMRDIAHLEITALCPLRDVPSHSNHGDPLSYYQTGDIIRA-GIKDIDRYH 200
L C+ S +++ + LE C L+ + + N +++ G + A G + +H
Sbjct: 156 LYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFA--VAWSNLGCVFNAQGEIWLAIHH 213
Query: 201 EKLAVSLYSSSLPPHLSGIKLGVISSEELPLYYRRSVELNSNSLESYENVMQSSLGFVNP 260
+ AV+L + L + I LG + E + L + SL V+ +L V
Sbjct: 214 FEKAVTLDPNFLDAY---INLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACV-- 268
Query: 261 GVVEFLLEKLGIDESNPPSLMRGLQSKNFSEDDF---ASALRKKQSASWALKCVKIGVDY 317
E L L ID + R ++ + D + A+AL++K S + A C +
Sbjct: 269 -YYEQGLIDLAID-----TYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRL 322
Query: 318 FKVGRHVDAMNE-----------------YNKALEIDKQNVEALVARGALYATKGSLNKA 360
H D++N Y KALE+ + A ++ +G L +A
Sbjct: 323 CPT--HADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEA 380
Query: 361 IEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAED 420
+ ++ A+ PT +A + G L+E + A Y +A+ ++ F DA
Sbjct: 381 LMHYKEAIRISPTFADAYSNM-------GNTLKEMQDVQGALQCYTRAIQINPAFADAHS 433
Query: 421 ALQKLHKYMQVIP 433
L +HK IP
Sbjct: 434 NLASIHKDSGNIP 446
Score = 32.3 bits (72), Expect = 0.88
Identities = 31/124 (25%), Positives = 50/124 (40%), Gaps = 21/124 (16%)
Query: 326 AMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTL 385
A+ Y +AL + + +Y +G ++ AI+ + A+E P +A L L
Sbjct: 244 AVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANAL 303
Query: 386 VERGGQLEEEEKFLNAESYYKKALALDETFKDA--------------EDALQKLHKYMQV 431
E+G E AE Y AL L T D+ E+A++ K ++V
Sbjct: 304 KEKGSVAE-------AEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEV 356
Query: 432 IPYF 435
P F
Sbjct: 357 FPEF 360
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 40.4 bits (93), Expect = 0.003
Identities = 33/128 (25%), Positives = 63/128 (49%), Gaps = 18/128 (14%)
Query: 308 LKCVKI-GVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGS-------LNK 359
L+C ++ Y K H A++ +KAL++ ++ + + L+ TKG+ L+K
Sbjct: 643 LECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVI---SELFFTKGNQLREQNLLDK 699
Query: 360 AIEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAE 419
A E + +A++ P Q + GG + K+++A +YY++AL L K +
Sbjct: 700 AFESYRVAVQLNPDQ-------AQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLK 752
Query: 420 DALQKLHK 427
+ L KL +
Sbjct: 753 ENLAKLDR 760
Score = 28.9 bits (63), Expect = 9.7
Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 27/120 (22%)
Query: 321 GRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKY 380
GR+ +A+ Y AL++ ++ AL G L +A ++ AL+ P H A
Sbjct: 389 GRNKEAIYHYRTALKLYPRHASALNNLGTLTRDTA---EAKMYYQRALQLHPQHNRA--- 442
Query: 381 LCQTLVERGGQLEEEEK-----------------FLNAESYYKKALALDETFKDAEDALQ 423
L G L+ +EK F +A S LA E FK+AE+ Q
Sbjct: 443 ----LFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQ 498
>gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo
sapiens]
Length = 807
Score = 40.0 bits (92), Expect = 0.004
Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 21/135 (15%)
Query: 314 GVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPT 373
G YF + A ++ ++LE++K A++ +G + +G L +AIE F+ AL+
Sbjct: 203 GTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVD 262
Query: 374 HRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDA--------------E 419
+A K L Q E G F A ++KAL L++ +
Sbjct: 263 FIDAYKSLGQAYRELG-------NFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQ 315
Query: 420 DALQKLHKYMQVIPY 434
+AL+ + +Q+ PY
Sbjct: 316 EALKNFKRCLQLEPY 330
Score = 38.1 bits (87), Expect = 0.016
Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
Query: 292 DDFASALRKKQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALY 351
+ F AL++K A K +G Y ++G A + KAL +++ +V+ L RG +
Sbjct: 251 ESFKEALKQKVDFIDAYK--SLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMML 308
Query: 352 ATKGSLNKAIEDFELALE 369
GSL +A+++F+ L+
Sbjct: 309 YHHGSLQEALKNFKRCLQ 326
Score = 32.3 bits (72), Expect = 0.88
Identities = 31/108 (28%), Positives = 47/108 (43%), Gaps = 8/108 (7%)
Query: 320 VGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARK 379
+GR +A+N+ KA+++ + + RG LY A EDF+ +LE A
Sbjct: 176 LGRINEAVNDLTKAIQL-QPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAML 234
Query: 380 YLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHK 427
Y T RG E E F K+AL F DA +L + ++
Sbjct: 235 YKGLTFFHRGLLKEAIESF-------KEALKQKVDFIDAYKSLGQAYR 275
>gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo
sapiens]
Length = 860
Score = 40.0 bits (92), Expect = 0.004
Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 21/135 (15%)
Query: 314 GVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPT 373
G YF + A ++ ++LE++K A++ +G + +G L +AIE F+ AL+
Sbjct: 256 GTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVD 315
Query: 374 HRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDA--------------E 419
+A K L Q E G F A ++KAL L++ +
Sbjct: 316 FIDAYKSLGQAYRELG-------NFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQ 368
Query: 420 DALQKLHKYMQVIPY 434
+AL+ + +Q+ PY
Sbjct: 369 EALKNFKRCLQLEPY 383
Score = 38.1 bits (87), Expect = 0.016
Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
Query: 292 DDFASALRKKQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALY 351
+ F AL++K A K +G Y ++G A + KAL +++ +V+ L RG +
Sbjct: 304 ESFKEALKQKVDFIDAYK--SLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMML 361
Query: 352 ATKGSLNKAIEDFELALE 369
GSL +A+++F+ L+
Sbjct: 362 YHHGSLQEALKNFKRCLQ 379
Score = 32.3 bits (72), Expect = 0.88
Identities = 31/108 (28%), Positives = 47/108 (43%), Gaps = 8/108 (7%)
Query: 320 VGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARK 379
+GR +A+N+ KA+++ + + RG LY A EDF+ +LE A
Sbjct: 229 LGRINEAVNDLTKAIQL-QPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAML 287
Query: 380 YLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHK 427
Y T RG E E F K+AL F DA +L + ++
Sbjct: 288 YKGLTFFHRGLLKEAIESF-------KEALKQKVDFIDAYKSLGQAYR 328
>gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2
[Homo sapiens]
Length = 438
Score = 39.7 bits (91), Expect = 0.005
Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 9/100 (9%)
Query: 320 VGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTH----- 374
+GR+ +A + + L +D N +AL RG + + KA++ F AL P H
Sbjct: 133 LGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACI 192
Query: 375 --RNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALD 412
RNA+ + E G + +E + A Y +AL +D
Sbjct: 193 ACRNAKALKAKK--EDGNKAFKEGNYKLAYELYTEALGID 230
Score = 36.6 bits (83), Expect = 0.046
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 4/109 (3%)
Query: 307 ALKCVKI-GVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFE 365
ALK K G FK G + A Y +AL ID N++ LY +G++N + +
Sbjct: 199 ALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKT---NAKLYCNRGTVNSKLRKLD 255
Query: 366 LALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDET 414
A+E+C + + R + E++ A Y+K ++T
Sbjct: 256 DAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKT 304
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 39.7 bits (91), Expect = 0.005
Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 9/100 (9%)
Query: 320 VGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTH----- 374
+GR+ +A + + L +D N +AL RG + + KA++ F AL P H
Sbjct: 189 LGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACI 248
Query: 375 --RNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALD 412
RNA+ + E G + +E + A Y +AL +D
Sbjct: 249 ACRNAKALKAKK--EDGNKAFKEGNYKLAYELYTEALGID 286
Score = 36.6 bits (83), Expect = 0.046
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 4/109 (3%)
Query: 307 ALKCVKI-GVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFE 365
ALK K G FK G + A Y +AL ID N++ LY +G++N + +
Sbjct: 255 ALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKT---NAKLYCNRGTVNSKLRKLD 311
Query: 366 LALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDET 414
A+E+C + + R + E++ A Y+K ++T
Sbjct: 312 DAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKT 360
>gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Homo
sapiens]
Length = 420
Score = 38.9 bits (89), Expect = 0.009
Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 3/119 (2%)
Query: 314 GVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENC-- 371
G F ++ A+N YN A+ ++ + + R A + +L+KAIED ALE
Sbjct: 297 GNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALELLMP 356
Query: 372 PTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQ 430
P NA + + V RG + E ++ Y+ AL +D + K + +K+ +Q
Sbjct: 357 PVTDNANARM-KAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIRNVIQ 414
>gi|4759336 Fanconi anemia, complementation group G [Homo sapiens]
Length = 622
Score = 38.5 bits (88), Expect = 0.012
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 9/88 (10%)
Query: 343 ALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAE 402
AL++RG + G KA++DF L+++ CP +R+ +L QTL + E + E
Sbjct: 516 ALISRGLEWVASGQDTKALQDFLLSVQMCPGNRDTYFHLLQTLKRLDRRDEATALWWRLE 575
Query: 403 SYYKKALALDETFKDAEDALQKLHKYMQ 430
+ +T EDAL L Y++
Sbjct: 576 A---------QTKGSHEDALWSLPLYLE 594
>gi|56606133 tetratricopeptide repeat domain 32 [Homo sapiens]
Length = 151
Score = 38.5 bits (88), Expect = 0.012
Identities = 25/90 (27%), Positives = 49/90 (54%), Gaps = 5/90 (5%)
Query: 315 VDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTH 374
+ YF+V + +AM++Y A+E+ RG + G + A+EDF+ L+ P
Sbjct: 67 IKYFRVDFY-EAMDDYTSAIEVQPNFEVPYYNRGLILYRLGYFDDALEDFKKVLDLNPGF 125
Query: 375 RNARKYLCQTLVERGGQLEEEEKFLNAESY 404
++A L QT++++ EE+++ A++Y
Sbjct: 126 QDATLSLKQTILDK----EEKQRRNVAKNY 151
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 38.1 bits (87), Expect = 0.016
Identities = 41/194 (21%), Positives = 76/194 (39%), Gaps = 30/194 (15%)
Query: 227 EELPLYYRRSVELNSNSLESYENVMQSSLGFVN-----PGVVEFLLEKLGIDESNPPSLM 281
EE Y R +EL N+ E+ + + S + P + +++ + +
Sbjct: 218 EEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQ 277
Query: 282 RGLQSKNFSEDDFASALRKKQSASWALKCVKIGVD---------------YFKVGRHVDA 326
Q+ SE D + K+ A++C G+ Y K+ ++ +A
Sbjct: 278 NKQQA--ISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEA 335
Query: 327 MNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNA--------R 378
+ +A+ +D +A RG G LN+A +DFE L P ++ A +
Sbjct: 336 EKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK 395
Query: 379 KYLCQTLVERGGQL 392
K L + ++E G L
Sbjct: 396 KPLKKVIIEETGNL 409
Score = 32.7 bits (73), Expect = 0.67
Identities = 50/232 (21%), Positives = 92/232 (39%), Gaps = 45/232 (19%)
Query: 238 ELNSNSLESYENVMQSSLGFVNPGVVEFLLEKLGIDESNPPSLMRGLQSKNFS---EDDF 294
E N ++SY+ + L V+ +L++L D+S SL + +S+ +
Sbjct: 79 ENTKNRIKSYDYEAWAKLD------VDRILDELDKDDSTHESLSQESESEEDGIHVDSQK 132
Query: 295 ASALRKKQSASW-------ALKCVKIGVD---------------YFKVGRHVDAMNEYNK 332
A L++K + + A+ C G+D YF++ + A ++ N
Sbjct: 133 ALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNL 192
Query: 333 ALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTH---RNARKYLCQTLVERG 389
A+ +++ +A RGA L +A +D+E LE P + N + + Q L +
Sbjct: 193 AVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKE 252
Query: 390 GQLEEEEKFL---------NAESYYKKALALDETFKDAEDALQKLHKYMQVI 432
+E + E+ K A+ E KD + K KY + I
Sbjct: 253 NSYPKEADIVIKSTEGERKQIEAQQNKQQAISE--KDRGNGFFKEGKYERAI 302
>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 37.4 bits (85), Expect = 0.027
Identities = 40/186 (21%), Positives = 74/186 (39%), Gaps = 25/186 (13%)
Query: 227 EELPLYYRRSVELNSNSLESYENVMQSSLGFVN-----PGVVEFLLEKLGIDESNPPSLM 281
EE Y R +EL N+ E+ + + S + P + +++ + +
Sbjct: 59 EEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQ 118
Query: 282 RGLQSKNFSEDDFASALRKKQSASWALKCVKIGVD---------------YFKVGRHVDA 326
Q+ SE D + K+ A++C G+ Y K+ ++ +A
Sbjct: 119 NKQQA--ISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEA 176
Query: 327 MNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLC---Q 383
+ +A+ +D +A RG G LN+A +DFE L P ++ A L +
Sbjct: 177 EKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK 236
Query: 384 TLVERG 389
L+E+G
Sbjct: 237 ELIEKG 242
Score = 30.4 bits (67), Expect = 3.3
Identities = 30/128 (23%), Positives = 53/128 (41%), Gaps = 14/128 (10%)
Query: 317 YFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTH-- 374
YF++ + A ++ N A+ +++ +A RGA L +A +D+E LE P +
Sbjct: 18 YFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFE 77
Query: 375 -RNARKYLCQTLVERGGQLEEEEKFL---------NAESYYKKALALDETFKDAEDALQK 424
N + + Q L + +E + E+ K A+ E KD + K
Sbjct: 78 ATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISE--KDRGNGFFK 135
Query: 425 LHKYMQVI 432
KY + I
Sbjct: 136 EGKYERAI 143
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 37.4 bits (85), Expect = 0.027
Identities = 40/186 (21%), Positives = 74/186 (39%), Gaps = 25/186 (13%)
Query: 227 EELPLYYRRSVELNSNSLESYENVMQSSLGFVN-----PGVVEFLLEKLGIDESNPPSLM 281
EE Y R +EL N+ E+ + + S + P + +++ + +
Sbjct: 218 EEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQ 277
Query: 282 RGLQSKNFSEDDFASALRKKQSASWALKCVKIGVD---------------YFKVGRHVDA 326
Q+ SE D + K+ A++C G+ Y K+ ++ +A
Sbjct: 278 NKQQA--ISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEA 335
Query: 327 MNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLC---Q 383
+ +A+ +D +A RG G LN+A +DFE L P ++ A L +
Sbjct: 336 EKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK 395
Query: 384 TLVERG 389
L+E+G
Sbjct: 396 ELIEKG 401
Score = 32.7 bits (73), Expect = 0.67
Identities = 50/232 (21%), Positives = 92/232 (39%), Gaps = 45/232 (19%)
Query: 238 ELNSNSLESYENVMQSSLGFVNPGVVEFLLEKLGIDESNPPSLMRGLQSKNFS---EDDF 294
E N ++SY+ + L V+ +L++L D+S SL + +S+ +
Sbjct: 79 ENTKNRIKSYDYEAWAKLD------VDRILDELDKDDSTHESLSQESESEEDGIHVDSQK 132
Query: 295 ASALRKKQSASW-------ALKCVKIGVD---------------YFKVGRHVDAMNEYNK 332
A L++K + + A+ C G+D YF++ + A ++ N
Sbjct: 133 ALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNL 192
Query: 333 ALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTH---RNARKYLCQTLVERG 389
A+ +++ +A RGA L +A +D+E LE P + N + + Q L +
Sbjct: 193 AVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKE 252
Query: 390 GQLEEEEKFL---------NAESYYKKALALDETFKDAEDALQKLHKYMQVI 432
+E + E+ K A+ E KD + K KY + I
Sbjct: 253 NSYPKEADIVIKSTEGERKQIEAQQNKQQAISE--KDRGNGFFKEGKYERAI 302
>gi|31542980 interferon-induced protein with tetratricopeptide
repeats 3 [Homo sapiens]
Length = 490
Score = 37.4 bits (85), Expect = 0.027
Identities = 44/185 (23%), Positives = 69/185 (37%), Gaps = 16/185 (8%)
Query: 268 EKLGIDESNPPSLMRGLQ----------SKNFSEDDFASALRKKQSASWALKCVKIGVDY 317
EK ++ N P GL K FS D A+ + V +G+
Sbjct: 160 EKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVK--VLLGLKL 217
Query: 318 FKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNA 377
K+ + + +ALE + L + Y KG L+KAIE F+ LE+ P +
Sbjct: 218 QKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYL 277
Query: 378 RKYLCQTLVERGGQLE---EEEKFLNAESYYK-KALALDETFKDAEDALQKLHKYMQVIP 433
+ + Q++ E E N E K A+D + K E L L+ Y +
Sbjct: 278 YHQIGCCYKAKVRQMQNTGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAE 337
Query: 434 YFLLE 438
+ E
Sbjct: 338 FLETE 342
>gi|72534658 interferon-induced protein with tetratricopeptide
repeats 3 [Homo sapiens]
Length = 490
Score = 37.4 bits (85), Expect = 0.027
Identities = 44/185 (23%), Positives = 69/185 (37%), Gaps = 16/185 (8%)
Query: 268 EKLGIDESNPPSLMRGLQ----------SKNFSEDDFASALRKKQSASWALKCVKIGVDY 317
EK ++ N P GL K FS D A+ + V +G+
Sbjct: 160 EKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVK--VLLGLKL 217
Query: 318 FKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNA 377
K+ + + +ALE + L + Y KG L+KAIE F+ LE+ P +
Sbjct: 218 QKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYL 277
Query: 378 RKYLCQTLVERGGQLE---EEEKFLNAESYYK-KALALDETFKDAEDALQKLHKYMQVIP 433
+ + Q++ E E N E K A+D + K E L L+ Y +
Sbjct: 278 YHQIGCCYKAKVRQMQNTGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAE 337
Query: 434 YFLLE 438
+ E
Sbjct: 338 FLETE 342
>gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo
sapiens]
Length = 504
Score = 37.0 bits (84), Expect = 0.036
Identities = 27/119 (22%), Positives = 54/119 (45%), Gaps = 7/119 (5%)
Query: 309 KCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELAL 368
K +++G G+ DA+++++ A++ D N A R ++ G A+ D +
Sbjct: 39 KHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVI 98
Query: 369 ENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHK 427
+ AR ++RG L ++ K AE +KK L + + + ++A +L K
Sbjct: 99 QLKMDFTAAR-------LQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIK 150
>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 36.6 bits (83), Expect = 0.046
Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 8/132 (6%)
Query: 296 SALRKKQSASWALKC-VKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATK 354
S K S S+ L + + + Y K+ + A+ +KAL +D N + L RG
Sbjct: 305 SEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLM 364
Query: 355 GSLNKAIEDFELALENCPTHRNARKY--LCQTLVERGGQLEEEEKFLNAESYYKKALALD 412
A DFE LE P ++ AR +CQ ++ + E ++ + A + K A
Sbjct: 365 NEFESAKGDFEKVLEVNPQNKAARLQISMCQ---KKAKEHNERDRRIYANMF--KKFAEQ 419
Query: 413 ETFKDAEDALQK 424
+ ++A A+ K
Sbjct: 420 DAKEEANKAMGK 431
>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 36.6 bits (83), Expect = 0.046
Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 8/132 (6%)
Query: 296 SALRKKQSASWALKC-VKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATK 354
S K S S+ L + + + Y K+ + A+ +KAL +D N + L RG
Sbjct: 305 SEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLM 364
Query: 355 GSLNKAIEDFELALENCPTHRNARKY--LCQTLVERGGQLEEEEKFLNAESYYKKALALD 412
A DFE LE P ++ AR +CQ ++ + E ++ + A + K A
Sbjct: 365 NEFESAKGDFEKVLEVNPQNKAARLQISMCQ---KKAKEHNERDRRIYANMF--KKFAEQ 419
Query: 413 ETFKDAEDALQK 424
+ ++A A+ K
Sbjct: 420 DAKEEANKAMGK 431
>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 36.6 bits (83), Expect = 0.046
Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 8/132 (6%)
Query: 296 SALRKKQSASWALKC-VKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATK 354
S K S S+ L + + + Y K+ + A+ +KAL +D N + L RG
Sbjct: 305 SEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLM 364
Query: 355 GSLNKAIEDFELALENCPTHRNARKY--LCQTLVERGGQLEEEEKFLNAESYYKKALALD 412
A DFE LE P ++ AR +CQ ++ + E ++ + A + K A
Sbjct: 365 NEFESAKGDFEKVLEVNPQNKAARLQISMCQ---KKAKEHNERDRRIYANMF--KKFAEQ 419
Query: 413 ETFKDAEDALQK 424
+ ++A A+ K
Sbjct: 420 DAKEEANKAMGK 431
>gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]
Length = 519
Score = 36.2 bits (82), Expect = 0.061
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 3/94 (3%)
Query: 284 LQSKNFSEDDFASALRKKQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEA 343
L+ N ++D +AL + L + +G + G A+ Y KA+E +N E
Sbjct: 148 LKQFNKAQDQLHNALNLNRHD---LTYIMLGKIHLLEGDLDKAIEVYKKAVEFSPENTEL 204
Query: 344 LVARGALYATKGSLNKAIEDFELALENCPTHRNA 377
L G LY G KA E AL PT+ A
Sbjct: 205 LTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKA 238
>gi|89179321 smooth muscle cell associated protein-1 isoform 3 [Homo
sapiens]
Length = 929
Score = 36.2 bits (82), Expect = 0.061
Identities = 23/85 (27%), Positives = 44/85 (51%), Gaps = 4/85 (4%)
Query: 317 YFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRN 376
+ K+ + A E +KA+E D +V+AL R G L++A+ D L+ C +
Sbjct: 53 HLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLD----LQRCVSLEP 108
Query: 377 ARKYLCQTLVERGGQLEEEEKFLNA 401
K + L GGQ++E+ +++++
Sbjct: 109 KNKVFQEALRNIGGQIQEKVRYMSS 133
>gi|29725607 smooth muscle cell associated protein-1 isoform 2 [Homo
sapiens]
Length = 944
Score = 36.2 bits (82), Expect = 0.061
Identities = 23/85 (27%), Positives = 44/85 (51%), Gaps = 4/85 (4%)
Query: 317 YFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRN 376
+ K+ + A E +KA+E D +V+AL R G L++A+ D L+ C +
Sbjct: 68 HLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLD----LQRCVSLEP 123
Query: 377 ARKYLCQTLVERGGQLEEEEKFLNA 401
K + L GGQ++E+ +++++
Sbjct: 124 KNKVFQEALRNIGGQIQEKVRYMSS 148
>gi|22749211 transmembrane and tetratricopeptide repeat containing 2
[Homo sapiens]
Length = 836
Score = 35.8 bits (81), Expect = 0.079
Identities = 28/102 (27%), Positives = 47/102 (46%), Gaps = 7/102 (6%)
Query: 313 IGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCP 372
+G Y ++ + +A + Y ++L ++ A + G L A G ++A + F A+E P
Sbjct: 649 MGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKLFLKAIELDP 708
Query: 373 THRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDET 414
T N + Q L+ EE + + A KKA LD T
Sbjct: 709 TKGNCYMHYGQFLL-------EEARLIEAAEMAKKAAELDST 743
>gi|27262638 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 35.8 bits (81), Expect = 0.079
Identities = 29/103 (28%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 326 AMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTL 385
A + K LE++ NV+AL+ R Y + L +A ED L+ P + A+K L +
Sbjct: 261 AFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSE-- 318
Query: 386 VERGGQLEEEEKFLNAESYYKKALALD-ETFKDAEDALQKLHK 427
VER L+ E ++ K+ + + E +D E + H+
Sbjct: 319 VER--DLKNSEAASETQTKGKRMVIQEIENSEDEEGKSGRKHE 359
Score = 32.3 bits (72), Expect = 0.88
Identities = 29/124 (23%), Positives = 57/124 (45%), Gaps = 15/124 (12%)
Query: 314 GVDYFKVGRHVDAMNEYNKALEIDK-------QNVEALVA-RGALYATKGSLNKAIEDFE 365
G + F+ G+ +A +Y+ A+ + + ++ L + R A Y +G+ + I+D
Sbjct: 452 GNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACYLKEGNCSGCIQDCN 511
Query: 366 LALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKL 425
ALE P + + L+ R E E++ A YK L +D + A D++ +L
Sbjct: 512 RALELHP-------FSMKPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGLQLANDSVNRL 564
Query: 426 HKYM 429
+ +
Sbjct: 565 SRIL 568
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,711,378
Number of Sequences: 37866
Number of extensions: 729721
Number of successful extensions: 2607
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 2448
Number of HSP's gapped (non-prelim): 176
length of query: 439
length of database: 18,247,518
effective HSP length: 105
effective length of query: 334
effective length of database: 14,271,588
effective search space: 4766710392
effective search space used: 4766710392
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.