Guide to the Human Genome
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Search of human proteins with 167466207

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|167466207 intercellular adhesion molecule 3 precursor [Homo
sapiens]
         (547 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|167466207 intercellular adhesion molecule 3 precursor [Homo s...  1102   0.0  
gi|189571583 intercellular adhesion molecule 5 precursor [Homo s...   469   e-132
gi|167466198 intercellular adhesion molecule 1 precursor [Homo s...   462   e-130
gi|153082722 intercellular adhesion molecule 2 precursor [Homo s...   119   5e-27
gi|153082719 intercellular adhesion molecule 2 precursor [Homo s...   119   5e-27
gi|153082699 intercellular adhesion molecule 2 precursor [Homo s...   119   5e-27
gi|153082686 intercellular adhesion molecule 2 precursor [Homo s...   119   5e-27
gi|153082696 intercellular adhesion molecule 2 precursor [Homo s...   119   5e-27
gi|4504561 intercellular adhesion molecule 4 isoform 1 precursor...    73   6e-13
gi|12545402 intercellular adhesion molecule 4 isoform 2 precurso...    73   6e-13
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]         63   8e-10
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]          63   8e-10
gi|85068578 intercellular adhesion molecule 4 isoform 3 precurso...    56   1e-07
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]       52   1e-06
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho...    49   1e-05
gi|118572606 hemicentin 1 [Homo sapiens]                               45   1e-04
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho...    44   3e-04
gi|40255013 carcinoembryonic antigen-related cell adhesion molec...    44   5e-04
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                    43   8e-04
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    43   8e-04
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]                    43   8e-04
gi|61742797 basal cell adhesion molecule isoform 2 precursor [Ho...    42   0.001
gi|31543106 basal cell adhesion molecule isoform 1 precursor [Ho...    42   0.001
gi|4827022 contactin 2 precursor [Homo sapiens]                        41   0.002
gi|157168355 CD22 molecule [Homo sapiens]                              41   0.002
gi|21686977 cell adhesion molecule 4 [Homo sapiens]                    40   0.006
gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens]      40   0.006
gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens]     39   0.012
gi|145275174 kin of IRRE-like 2 isoform c [Homo sapiens]               39   0.016
gi|145275172 kin of IRRE-like 2 isoform b [Homo sapiens]               39   0.016

>gi|167466207 intercellular adhesion molecule 3 precursor [Homo
           sapiens]
          Length = 547

 Score = 1102 bits (2851), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 1   MATMVPSVLWPRACWTLLVCCLLTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSS 60
           MATMVPSVLWPRACWTLLVCCLLTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSS
Sbjct: 1   MATMVPSVLWPRACWTLLVCCLLTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSS 60

Query: 61  EKIALETSLSKELVASGMGWAAFNLSNVTGNSRILCSVYCNGSQITGSSNITVYRLPERV 120
           EKIALETSLSKELVASGMGWAAFNLSNVTGNSRILCSVYCNGSQITGSSNITVYRLPERV
Sbjct: 61  EKIALETSLSKELVASGMGWAAFNLSNVTGNSRILCSVYCNGSQITGSSNITVYRLPERV 120

Query: 121 ELAPLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAVEEPAEVTATVLAS 180
           ELAPLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAVEEPAEVTATVLAS
Sbjct: 121 ELAPLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAVEEPAEVTATVLAS 180

Query: 181 RDDHGAPFSCRTELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLVAPRFLEVETSWPVD 240
           RDDHGAPFSCRTELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLVAPRFLEVETSWPVD
Sbjct: 181 RDDHGAPFSCRTELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLVAPRFLEVETSWPVD 240

Query: 241 CTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVCNVTLGG 300
           CTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVCNVTLGG
Sbjct: 241 CTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVCNVTLGG 300

Query: 301 ERREARENLTVFSFLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQL 360
           ERREARENLTVFSFLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQL
Sbjct: 301 ERREARENLTVFSFLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQL 360

Query: 361 QLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHV 420
           QLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHV
Sbjct: 361 QLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHV 420

Query: 421 LQCQARGNPYPELRCLKEGSSREVPVGIPFFVNVTHNGTYQCQASSSRGKYTLVVVMDIE 480
           LQCQARGNPYPELRCLKEGSSREVPVGIPFFVNVTHNGTYQCQASSSRGKYTLVVVMDIE
Sbjct: 421 LQCQARGNPYPELRCLKEGSSREVPVGIPFFVNVTHNGTYQCQASSSRGKYTLVVVMDIE 480

Query: 481 AGSSHFVPVFVAVLLTLGVVTIVLALMYVFREHQRSGSYHVREESTYLPLTSMQPTEAMG 540
           AGSSHFVPVFVAVLLTLGVVTIVLALMYVFREHQRSGSYHVREESTYLPLTSMQPTEAMG
Sbjct: 481 AGSSHFVPVFVAVLLTLGVVTIVLALMYVFREHQRSGSYHVREESTYLPLTSMQPTEAMG 540

Query: 541 EEPSRAE 547
           EEPSRAE
Sbjct: 541 EEPSRAE 547


>gi|189571583 intercellular adhesion molecule 5 precursor [Homo
           sapiens]
          Length = 924

 Score =  469 bits (1208), Expect = e-132
 Identities = 240/460 (52%), Positives = 311/460 (67%), Gaps = 6/460 (1%)

Query: 27  VQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSSEKIALETSLSKELVASGMGWAAFNLS 86
           V  + F   ++P+   +  GGSL++NCST+CP  E+  LETSL +     G+ W A  L 
Sbjct: 29  VSQEPFWADLQPRVAFVERGGSLWLNCSTNCPRPERGGLETSLRRNGTQRGLRWLARQLV 88

Query: 87  NVTG-NSRILCSVYCNGSQITGSSNITVYRLPERVELAPLPPWQPVGQNFTLRCQVEDGS 145
           ++    ++ +C   C    +     I  ++ P+RVEL PLPPWQPVG+NFTL C+V    
Sbjct: 89  DIREPETQPVCFFRCARRTLQARGLIRTFQRPDRVELMPLPPWQPVGENFTLSCRVPGAG 148

Query: 146 PRTSLTVVLLRWEEELSRQPAVEEP-----AEVTATVLASRDDHGAPFSCRTELDMQPQG 200
           PR SLT+ LLR  +EL R+    EP     A +TATVLA R+DHGA FSCR ELD++P G
Sbjct: 149 PRASLTLTLLRGAQELIRRSFAGEPPRARGAVLTATVLARREDHGANFSCRAELDLRPHG 208

Query: 201 LGLFVNTSAPRQLRTFVLPVTPPRLVAPRFLEVETSWPVDCTLDGLFPASEAQVYLALGD 260
           LGLF N+SAPR+LRTF L    PRL APR LEV +  PV CTLDGLFPASEA+VYLALGD
Sbjct: 209 LGLFENSSAPRELRTFSLSPDAPRLAAPRLLEVGSERPVSCTLDGLFPASEARVYLALGD 268

Query: 261 QMLNATVMNHGDTLTATATATARADQEGAREIVCNVTLGGERREARENLTVFSFLGPIVN 320
           Q L+  V   GD   ATATATA A+QEGAR++VCNVTLGGE RE REN+T++SF  P++ 
Sbjct: 269 QNLSPDVTLEGDAFVATATATASAEQEGARQLVCNVTLGGENRETRENVTIYSFPAPLLT 328

Query: 321 LSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQLQLNATESDDGRSFFCSATLE 380
           LSEP+  EG  VTV+C AGA+  VTL+GVPAA PGQPAQLQLNATE+DD RSFFC ATL+
Sbjct: 329 LSEPSVSEGQMVTVTCAAGAQALVTLEGVPAAVPGQPAQLQLNATENDDRRSFFCDATLD 388

Query: 381 VDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYPELRCLKEGS 440
           VDGE L +N S +LRVLY P++D + CP+   W +     L+C+ARGNP P + C +   
Sbjct: 389 VDGETLIKNRSAELRVLYAPRLDDSDCPRSWTWPEGPEQTLRCEARGNPEPSVHCARSDG 448

Query: 441 SREVPVGIPFFVNVTHNGTYQCQASSSRGKYTLVVVMDIE 480
              + +G+   V    +GTY+C+A++ +G+    V + +E
Sbjct: 449 GAVLALGLLGPVTRALSGTYRCKAANDQGEAVKDVTLTVE 488



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 97/381 (25%), Positives = 145/381 (38%), Gaps = 51/381 (13%)

Query: 117 PERVELAPLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAVEEPAEV-TA 175
           P+   LA  P    VG    + C ++   P +   V L   ++ LS    +E  A V TA
Sbjct: 228 PDAPRLAA-PRLLEVGSERPVSCTLDGLFPASEARVYLALGDQNLSPDVTLEGDAFVATA 286

Query: 176 TVLASRDDHGA-PFSCRTELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLVAPRFLEVE 234
           T  AS +  GA    C   L  +        N      +  +  P     L  P   E +
Sbjct: 287 TATASAEQEGARQLVCNVTLGGE--------NRETRENVTIYSFPAPLLTLSEPSVSEGQ 338

Query: 235 TSWPVDCTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVC 294
               V C       A+ AQ  + L  + + A V      L   AT     + +  R   C
Sbjct: 339 MV-TVTC-------AAGAQALVTL--EGVPAAVPGQPAQLQLNAT-----ENDDRRSFFC 383

Query: 295 NVTLG--GERREARENLTVFSFLGPIVNLSEP----TAHEGSTVTVSCMAGARVQVTL-- 346
           + TL   GE      +  +     P ++ S+     T  EG   T+ C A    + ++  
Sbjct: 384 DATLDVDGETLIKNRSAELRVLYAPRLDDSDCPRSWTWPEGPEQTLRCEARGNPEPSVHC 443

Query: 347 ---DGVPAAAPGQ--PAQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPK 401
              DG    A G   P    L+ T       + C A  +  GE +     V L V Y P 
Sbjct: 444 ARSDGGAVLALGLLGPVTRALSGT-------YRCKAAND-QGEAV---KDVTLTVEYAPA 492

Query: 402 IDRATCPQHLKWKDKTRHVLQCQARGNPYPELRCLKEGSSREVPVGIPFFVNVTHNGTYQ 461
           +D   CP+ + W + T   L C A G P P++ C++ G    V  G+   V   H GTY+
Sbjct: 493 LDSVGCPERITWLEGTEASLSCVAHGVPPPDVICVRSGELGAVIEGL-LRVAREHAGTYR 551

Query: 462 CQASSSRGKYTLVVVMDIEAG 482
           C+A++ RG     V + +E G
Sbjct: 552 CEATNPRGSAAKNVAVTVEYG 572



 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 110/475 (23%), Positives = 180/475 (37%), Gaps = 83/475 (17%)

Query: 42  VLSAGGSLFVNCSTD--CPSSEK---IAL-ETSLSKELVASGMGWAAFNLSNVT----GN 91
           +L  G    V+C+ D   P+SE    +AL + +LS ++   G  + A   +  +    G 
Sbjct: 238 LLEVGSERPVSCTLDGLFPASEARVYLALGDQNLSPDVTLEGDAFVATATATASAEQEGA 297

Query: 92  SRILCSVYCNGSQITGSSNITVYRLPERVELAPLPPWQPVGQNFTLRCQVEDGSPRTSLT 151
            +++C+V   G       N+T+Y  P  + L    P    GQ  T+ C     +  T   
Sbjct: 298 RQLVCNVTLGGENRETRENVTIYSFPAPL-LTLSEPSVSEGQMVTVTCAAGAQALVT--- 353

Query: 152 VVLLRWEEELSRQPAVEEPAEVTATVLASRDDHGAPFSCRTELDMQPQGLGLFVNTSAPR 211
                    L   PA          + A+ +D    F C   LD+   G  L  N SA  
Sbjct: 354 ---------LEGVPAAVPGQPAQLQLNATENDDRRSFFCDATLDVD--GETLIKNRSA-- 400

Query: 212 QLRTFVLPVTPPRLVAPRFLEVET----SWP------VDCTLDGLFPASEAQVYLALGDQ 261
           +LR          L APR  + +     +WP      + C   G     E  V+ A  D 
Sbjct: 401 ELRV---------LYAPRLDDSDCPRSWTWPEGPEQTLRCEARG---NPEPSVHCARSD- 447

Query: 262 MLNATVMNHG--DTLTATATATAR---ADQEGAREIVCNVTLGGERREARENLTVFSFLG 316
                V+  G    +T   + T R   A+ +G  E V +VTL  E   A +++     + 
Sbjct: 448 --GGAVLALGLLGPVTRALSGTYRCKAANDQG--EAVKDVTLTVEYAPALDSVGCPERI- 502

Query: 317 PIVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQLQLNATESDDGRSFFCS 376
                   T  EG+  ++SC+A       +  V +   G   +  L       G ++ C 
Sbjct: 503 --------TWLEGTEASLSCVAHGVPPPDVICVRSGELGAVIEGLLRVAREHAG-TYRCE 553

Query: 377 ATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYPELRCL 436
           AT            +V + V YGP+ +  +CP +  W + +  +  C+  G P P ++C+
Sbjct: 554 ATNPRGSAA----KNVAVTVEYGPRFEEPSCPSNWTWVEGSGRLFSCEVDGKPQPSVKCV 609

Query: 437 KEGSSRE---VPVG-------IPFFVNVTHNGTYQCQASSSRGKYTLVVVMDIEA 481
             G + E   +P+         P    V   G Y C A++  G     VV+  E+
Sbjct: 610 GSGGATEGVLLPLAPPDPSPRAPRIPRVLAPGIYVCNATNRHGSVAKTVVVSAES 664



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 59/228 (25%), Positives = 88/228 (38%), Gaps = 37/228 (16%)

Query: 274 LTATATATARADQEGAREIVCNVTLGGERREARENLTVFSFLGPIVNLSEPTAH------ 327
           L A      R  +E A    C  T    R  A +N+ V    GP     EP+        
Sbjct: 532 LGAVIEGLLRVAREHAGTYRCEAT--NPRGSAAKNVAVTVEYGP--RFEEPSCPSNWTWV 587

Query: 328 EGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQLQLNATESDDGRS----------FFCSA 377
           EGS    SC    + Q ++  V +    +   L L   +                + C+A
Sbjct: 588 EGSGRLFSCEVDGKPQPSVKCVGSGGATEGVLLPLAPPDPSPRAPRIPRVLAPGIYVCNA 647

Query: 378 TLEVDGEFLHRNSSVQLRVLYG----PKIDRATCPQHLKWKDKTR-HVLQCQARGNPYPE 432
           T        +R+ SV   V+      P++D +TCP H  W +      L C ARG P P 
Sbjct: 648 T--------NRHGSVAKTVVVSAESPPEMDESTCPSHQTWLEGAEASALACAARGRPSPG 699

Query: 433 LRCLKEGSSREVPVGIPFFVNVTHNGTYQCQASSSRGKYTLVVVMDIE 480
           +RC +EG    +P      V+    GTY C A+++ G  +  V + +E
Sbjct: 700 VRCSREG----IPWPEQQRVSREDAGTYHCVATNAHGTDSRTVTVGVE 743


>gi|167466198 intercellular adhesion molecule 1 precursor [Homo
           sapiens]
          Length = 532

 Score =  462 bits (1189), Expect = e-130
 Identities = 249/532 (46%), Positives = 334/532 (62%), Gaps = 14/532 (2%)

Query: 4   MVPSVLWPRACWTLLVCCLLTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSSEKI 63
           M PS   P     L++   L PG    +    V P   +L  GGS+ V CST C   + +
Sbjct: 1   MAPSSPRPALPALLVLLGALFPGPGNAQ--TSVSPSKVILPRGGSVLVTCSTSCDQPKLL 58

Query: 64  ALETSL-SKELVASGMGWAAFNLSNVTGNSRILCSVYCNGSQITGSSNITVYRLPERVEL 122
            +ET L  KEL+  G     + LSNV  +S+ +C   C   Q T  + +TVY  PERVEL
Sbjct: 59  GIETPLPKKELLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYWTPERVEL 118

Query: 123 APLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAVEEPAEVTATVLASRD 182
           APLP WQPVG+N TLRCQVE G+PR +LTVVLLR E+EL R+PAV EPAEVT TVL  RD
Sbjct: 119 APLPSWQPVGKNLTLRCQVEGGAPRANLTVVLLRGEKELKREPAVGEPAEVTTTVLVRRD 178

Query: 183 DHGAPFSCRTELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLVAPRFLEVETSWPVDCT 242
            HGA FSCRTELD++PQGL LF NTSAP QL+TFVLP TPP+LV+PR LEV+T   V C+
Sbjct: 179 HHGANFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLVSPRVLEVDTQGTVVCS 238

Query: 243 LDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVCNVTLGGER 302
           LDGLFP SEAQV+LALGDQ LN TV    D+ +A A+ +  A+ EG + + C V LG + 
Sbjct: 239 LDGLFPVSEAQVHLALGDQRLNPTVTYGNDSFSAKASVSVTAEDEGTQRLTCAVILGNQS 298

Query: 303 REARENLTVFSFLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQLQL 362
           +E  + +T++SF  P V L++P   EG+ VTV C A  R +VTL+GVPA   G  AQL L
Sbjct: 299 QETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTLNGVPAQPLGPRAQLLL 358

Query: 363 NATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQ 422
            AT  D+GRSF CSATLEV G+ +H+N + +LRVLYGP++D   CP +  W + ++    
Sbjct: 359 KATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPM 418

Query: 423 CQARGNPYPELRCLKEGSSREVPVGIPFFVNVTHNGTYQCQASSSRGKYTLVVVMDIEAG 482
           CQA GNP PEL+CLK+G+   +P+G    V     GTY C+A S++G+ T  V +++   
Sbjct: 419 CQAWGNPLPELKCLKDGTF-PLPIGESVTVTRDLEGTYLCRARSTQGEVTRKVTVNV--- 474

Query: 483 SSHFVPVFVAVLLTLGVVTIVLAL----MYVFREHQRSGSYHVREESTYLPL 530
                P +  V++T+    +++       Y++   ++   Y +++     P+
Sbjct: 475 ---LSPRYEIVIITVVAAAVIMGTAGLSTYLYNRQRKIKKYRLQQAQKGTPM 523


>gi|153082722 intercellular adhesion molecule 2 precursor [Homo
           sapiens]
          Length = 275

 Score =  119 bits (299), Expect = 5e-27
 Identities = 77/214 (35%), Positives = 112/214 (52%), Gaps = 9/214 (4%)

Query: 18  LVCCLLTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSSEKIALETSLSKELVASG 77
           L+CC   PG   + F + V P+   +   GSL VNCST C   E   LETSL K L+   
Sbjct: 16  LICC---PGSDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQ 72

Query: 78  MGWAAFNLSNVTGNSRILCSVYCNGSQITGSSNITVYRLPERVELAPLPPWQPVGQNFTL 137
             W  + +SN++ ++ + C   C+G Q + +SN++VY+ P +V L   P    VG++FT+
Sbjct: 73  AQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTI 132

Query: 138 RCQVEDGSPRTSLTVVLLRWEEELSRQ---PAVEEPAEVTATV--LASRDDHGAPFSCRT 192
            C+V    P  SLT+ L R  E L  +    A   P E TAT    A R+D    FSC  
Sbjct: 133 ECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLA 192

Query: 193 ELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLV 226
            LD+  +G  +F   SAP+ L  +  PV+  ++V
Sbjct: 193 VLDLMSRGGNIFHKHSAPKMLEIYE-PVSDSQMV 225


>gi|153082719 intercellular adhesion molecule 2 precursor [Homo
           sapiens]
          Length = 275

 Score =  119 bits (299), Expect = 5e-27
 Identities = 77/214 (35%), Positives = 112/214 (52%), Gaps = 9/214 (4%)

Query: 18  LVCCLLTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSSEKIALETSLSKELVASG 77
           L+CC   PG   + F + V P+   +   GSL VNCST C   E   LETSL K L+   
Sbjct: 16  LICC---PGSDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQ 72

Query: 78  MGWAAFNLSNVTGNSRILCSVYCNGSQITGSSNITVYRLPERVELAPLPPWQPVGQNFTL 137
             W  + +SN++ ++ + C   C+G Q + +SN++VY+ P +V L   P    VG++FT+
Sbjct: 73  AQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTI 132

Query: 138 RCQVEDGSPRTSLTVVLLRWEEELSRQ---PAVEEPAEVTATV--LASRDDHGAPFSCRT 192
            C+V    P  SLT+ L R  E L  +    A   P E TAT    A R+D    FSC  
Sbjct: 133 ECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLA 192

Query: 193 ELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLV 226
            LD+  +G  +F   SAP+ L  +  PV+  ++V
Sbjct: 193 VLDLMSRGGNIFHKHSAPKMLEIYE-PVSDSQMV 225


>gi|153082699 intercellular adhesion molecule 2 precursor [Homo
           sapiens]
          Length = 275

 Score =  119 bits (299), Expect = 5e-27
 Identities = 77/214 (35%), Positives = 112/214 (52%), Gaps = 9/214 (4%)

Query: 18  LVCCLLTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSSEKIALETSLSKELVASG 77
           L+CC   PG   + F + V P+   +   GSL VNCST C   E   LETSL K L+   
Sbjct: 16  LICC---PGSDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQ 72

Query: 78  MGWAAFNLSNVTGNSRILCSVYCNGSQITGSSNITVYRLPERVELAPLPPWQPVGQNFTL 137
             W  + +SN++ ++ + C   C+G Q + +SN++VY+ P +V L   P    VG++FT+
Sbjct: 73  AQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTI 132

Query: 138 RCQVEDGSPRTSLTVVLLRWEEELSRQ---PAVEEPAEVTATV--LASRDDHGAPFSCRT 192
            C+V    P  SLT+ L R  E L  +    A   P E TAT    A R+D    FSC  
Sbjct: 133 ECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLA 192

Query: 193 ELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLV 226
            LD+  +G  +F   SAP+ L  +  PV+  ++V
Sbjct: 193 VLDLMSRGGNIFHKHSAPKMLEIYE-PVSDSQMV 225


>gi|153082686 intercellular adhesion molecule 2 precursor [Homo
           sapiens]
          Length = 275

 Score =  119 bits (299), Expect = 5e-27
 Identities = 77/214 (35%), Positives = 112/214 (52%), Gaps = 9/214 (4%)

Query: 18  LVCCLLTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSSEKIALETSLSKELVASG 77
           L+CC   PG   + F + V P+   +   GSL VNCST C   E   LETSL K L+   
Sbjct: 16  LICC---PGSDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQ 72

Query: 78  MGWAAFNLSNVTGNSRILCSVYCNGSQITGSSNITVYRLPERVELAPLPPWQPVGQNFTL 137
             W  + +SN++ ++ + C   C+G Q + +SN++VY+ P +V L   P    VG++FT+
Sbjct: 73  AQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTI 132

Query: 138 RCQVEDGSPRTSLTVVLLRWEEELSRQ---PAVEEPAEVTATV--LASRDDHGAPFSCRT 192
            C+V    P  SLT+ L R  E L  +    A   P E TAT    A R+D    FSC  
Sbjct: 133 ECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLA 192

Query: 193 ELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLV 226
            LD+  +G  +F   SAP+ L  +  PV+  ++V
Sbjct: 193 VLDLMSRGGNIFHKHSAPKMLEIYE-PVSDSQMV 225


>gi|153082696 intercellular adhesion molecule 2 precursor [Homo
           sapiens]
          Length = 275

 Score =  119 bits (299), Expect = 5e-27
 Identities = 77/214 (35%), Positives = 112/214 (52%), Gaps = 9/214 (4%)

Query: 18  LVCCLLTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSSEKIALETSLSKELVASG 77
           L+CC   PG   + F + V P+   +   GSL VNCST C   E   LETSL K L+   
Sbjct: 16  LICC---PGSDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQ 72

Query: 78  MGWAAFNLSNVTGNSRILCSVYCNGSQITGSSNITVYRLPERVELAPLPPWQPVGQNFTL 137
             W  + +SN++ ++ + C   C+G Q + +SN++VY+ P +V L   P    VG++FT+
Sbjct: 73  AQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTI 132

Query: 138 RCQVEDGSPRTSLTVVLLRWEEELSRQ---PAVEEPAEVTATV--LASRDDHGAPFSCRT 192
            C+V    P  SLT+ L R  E L  +    A   P E TAT    A R+D    FSC  
Sbjct: 133 ECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLA 192

Query: 193 ELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLV 226
            LD+  +G  +F   SAP+ L  +  PV+  ++V
Sbjct: 193 VLDLMSRGGNIFHKHSAPKMLEIYE-PVSDSQMV 225


>gi|4504561 intercellular adhesion molecule 4 isoform 1 precursor
           [Homo sapiens]
          Length = 271

 Score = 73.2 bits (178), Expect = 6e-13
 Identities = 64/199 (32%), Positives = 88/199 (44%), Gaps = 21/199 (10%)

Query: 23  LTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSSEKIALETSLSKELVASGMGWAA 82
           L P      F +R+ P+   +  G S+ +NCS  CP  +  +L T L +     G GW +
Sbjct: 39  LAPSGTSVPFWVRMSPEFVAVQPGKSVQLNCSNSCPQPQNSSLRTPLRQGKTLRGPGWVS 98

Query: 83  FNLSNVTGNSRIL-CSVYCNGSQITGSSNITVYRLPERVELAPLPPWQPV--GQNFTLRC 139
           + L +V   S +  C V C G     +S IT Y+ P  V L P     PV  G+ +TLRC
Sbjct: 99  YQLLDVRAWSSLAHCLVTCAGKTRWATSRITAYKPPHSVILEP-----PVLKGRKYTLRC 153

Query: 140 QVEDGSPRTSLTVVL-----LRWEEELSRQPAVEEPAEVTAT--VLASRDDHGAPFSCRT 192
            V    P   L V L     + + E L R   + + A VT T    A   D   P  C  
Sbjct: 154 HVTQVFPVGYLVVTLRHGSRVIYSESLERFTGL-DLANVTLTYEFAAGPRDFWQPVICHA 212

Query: 193 ELDMQPQGLGLFV-NTSAP 210
            L++     GL V N+SAP
Sbjct: 213 RLNLD----GLVVRNSSAP 227


>gi|12545402 intercellular adhesion molecule 4 isoform 2 precursor
           [Homo sapiens]
          Length = 237

 Score = 73.2 bits (178), Expect = 6e-13
 Identities = 64/199 (32%), Positives = 88/199 (44%), Gaps = 21/199 (10%)

Query: 23  LTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSSEKIALETSLSKELVASGMGWAA 82
           L P      F +R+ P+   +  G S+ +NCS  CP  +  +L T L +     G GW +
Sbjct: 39  LAPSGTSVPFWVRMSPEFVAVQPGKSVQLNCSNSCPQPQNSSLRTPLRQGKTLRGPGWVS 98

Query: 83  FNLSNVTGNSRIL-CSVYCNGSQITGSSNITVYRLPERVELAPLPPWQPV--GQNFTLRC 139
           + L +V   S +  C V C G     +S IT Y+ P  V L P     PV  G+ +TLRC
Sbjct: 99  YQLLDVRAWSSLAHCLVTCAGKTRWATSRITAYKPPHSVILEP-----PVLKGRKYTLRC 153

Query: 140 QVEDGSPRTSLTVVL-----LRWEEELSRQPAVEEPAEVTAT--VLASRDDHGAPFSCRT 192
            V    P   L V L     + + E L R   + + A VT T    A   D   P  C  
Sbjct: 154 HVTQVFPVGYLVVTLRHGSRVIYSESLERFTGL-DLANVTLTYEFAAGPRDFWQPVICHA 212

Query: 193 ELDMQPQGLGLFV-NTSAP 210
            L++     GL V N+SAP
Sbjct: 213 RLNLD----GLVVRNSSAP 227


>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
          Length = 398

 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 65/258 (25%), Positives = 109/258 (42%), Gaps = 44/258 (17%)

Query: 303 REARENLTVFSF-LGPIVNLSEPTAHEGSTVTVSCMAGAR---VQVTLDGVPAAAPGQPA 358
           R A+  +TV      PI+   + +  E  T T++C +       ++T         G+P 
Sbjct: 118 RTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPT 177

Query: 359 QLQ---------------LNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKID 403
           ++Q                  T  DDG S  CS   E   +   R++S ++ VLY P   
Sbjct: 178 RIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHE-SLKGADRSTSQRIEVLYTPTAM 236

Query: 404 RATCPQHLKWKDKTRHVLQCQARGNPYPELRCL-KEGS------SREVPVGIPFFVNVTH 456
               P H +   K   +L C+ RGNP P+     KEGS      ++E  +  PF +N + 
Sbjct: 237 IRPDPPHPREGQKL--LLHCEGRGNPVPQQYLWEKEGSVPPLKMTQESALIFPF-LNKSD 293

Query: 457 NGTYQCQASSSRGKYTLVVVMDIE------AGSSHFVPVFVAVLLTLGVVTIVLALMYVF 510
           +GTY C A+S+ G Y     +++       + SS +  +   +   +  +  +L +M +F
Sbjct: 294 SGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSSTYHAIIGGI---VAFIVFLLLIMLIF 350

Query: 511 REHQRSGSYHVREESTYL 528
             H     Y +R + TYL
Sbjct: 351 LGH-----YLIRHKGTYL 363


>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
          Length = 432

 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 65/258 (25%), Positives = 109/258 (42%), Gaps = 44/258 (17%)

Query: 303 REARENLTVFSF-LGPIVNLSEPTAHEGSTVTVSCMAGAR---VQVTLDGVPAAAPGQPA 358
           R A+  +TV      PI+   + +  E  T T++C +       ++T         G+P 
Sbjct: 152 RTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPT 211

Query: 359 QLQ---------------LNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKID 403
           ++Q                  T  DDG S  CS   E   +   R++S ++ VLY P   
Sbjct: 212 RIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHE-SLKGADRSTSQRIEVLYTPTAM 270

Query: 404 RATCPQHLKWKDKTRHVLQCQARGNPYPELRCL-KEGS------SREVPVGIPFFVNVTH 456
               P H +   K   +L C+ RGNP P+     KEGS      ++E  +  PF +N + 
Sbjct: 271 IRPDPPHPREGQKL--LLHCEGRGNPVPQQYLWEKEGSVPPLKMTQESALIFPF-LNKSD 327

Query: 457 NGTYQCQASSSRGKYTLVVVMDIE------AGSSHFVPVFVAVLLTLGVVTIVLALMYVF 510
           +GTY C A+S+ G Y     +++       + SS +  +   +   +  +  +L +M +F
Sbjct: 328 SGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSSTYHAIIGGI---VAFIVFLLLIMLIF 384

Query: 511 REHQRSGSYHVREESTYL 528
             H     Y +R + TYL
Sbjct: 385 LGH-----YLIRHKGTYL 397


>gi|85068578 intercellular adhesion molecule 4 isoform 3 precursor
           [Homo sapiens]
          Length = 272

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 1/109 (0%)

Query: 23  LTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSSEKIALETSLSKELVASGMGWAA 82
           L P      F +R+ P+   +  G S+ +NCS  CP  +  +L T L +     G GW +
Sbjct: 39  LAPSGTSVPFWVRMSPEFVAVQPGKSVQLNCSNSCPQPQNSSLRTPLRQGKTLRGPGWVS 98

Query: 83  FNLSNVTGNSRIL-CSVYCNGSQITGSSNITVYRLPERVELAPLPPWQP 130
           + L +V   S +  C V C G     +S IT Y +P  +       W+P
Sbjct: 99  YQLLDVRAWSSLAHCLVTCAGKTRWATSRITAYSVPGGLLGGDPEAWKP 147


>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
          Length = 437

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 44/162 (27%), Positives = 74/162 (45%), Gaps = 24/162 (14%)

Query: 360 LQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVL---YGPKIDRATCPQHLKWKDK 416
           L      SDDG +  C     VD E L+    V ++VL   Y P +     P     ++ 
Sbjct: 190 LDFRVDRSDDGVAVIC----RVDHESLNATPQVAMQVLEIHYTPSVK--IIPSTPFPQEG 243

Query: 417 TRHVLQCQARGNPYPE-LRCLKEG-----------SSREVPVGIPFFVNVTHNGTYQCQA 464
              +L C+++G P PE +   K+G           S RE+ +    F+N T NGTY+C+A
Sbjct: 244 QPLILTCESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNI---LFLNKTDNGTYRCEA 300

Query: 465 SSSRGKYTLVVVMDIEAGSSHFVPVFVAVLLTLGVVTIVLAL 506
           +++ G+ +   V+ +    +  +P  +   LT   VT  +A+
Sbjct: 301 TNTIGQSSAEYVLIVHDVPNTLLPTTIIPSLTTATVTTTVAI 342


>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
           sapiens]
          Length = 414

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 66/257 (25%), Positives = 103/257 (40%), Gaps = 45/257 (17%)

Query: 306 RENLTVFSFLGP----IVNLSEPTAHEGSTVTVSCMAGARVQVT----------LDGVPA 351
           +E+ T  + L P    ++++ + TA EG  + V+C A A    T          L G   
Sbjct: 132 QESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSE 191

Query: 352 AAPGQP-----AQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQ--LRVLYGPKID- 403
                      +QL L   + DDG    C    +V+   +  N   Q  L V Y P++  
Sbjct: 192 VEEWSDMYTVTSQLMLKVHKEDDGVPVIC----QVEHPAVTGNLQTQRYLEVQYKPQVHI 247

Query: 404 RATCPQHLKWKDKTRHVLQCQARGNPYPEL----RCLKEGSSREVPVGIPFFVN---VTH 456
           + T P     ++     L C+A G P P +    R   E     V  G   F+N    T 
Sbjct: 248 QMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTD 307

Query: 457 NGTYQCQASSSRGKY---TLVVVMDIEAGS-------SHFVPVFVAVLLTLGVVTIVLAL 506
           NGTY+C+AS+  GK     ++ V D  AG         H V   V  ++   ++ +++ L
Sbjct: 308 NGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIIL 367

Query: 507 MYVFREHQRSGSYHVRE 523
              F  H+  G+Y   E
Sbjct: 368 GRYFARHK--GTYFTHE 382


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 43/161 (26%), Positives = 69/161 (42%), Gaps = 22/161 (13%)

Query: 328  EGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQLQLNATESDDGRSF-FCSATLEVDGEF- 385
            E ++V+++C A     + L  +     G P  L  +      GR       T+E  G++ 
Sbjct: 2400 EKNSVSLTCEASG---IPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYT 2456

Query: 386  -LHRNSSVQLRVLYG------PKIDRATCPQHLKWKDKTRHVLQCQARGNPYPEL----- 433
             + RN++ + R ++G      P I      + +K K+K    L C+  GNP PE+     
Sbjct: 2457 CVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKD 2516

Query: 434  -RCLKEGSSREVPVGIPFF----VNVTHNGTYQCQASSSRG 469
             + L+E  +  +  G  F     V V H G Y C ASS  G
Sbjct: 2517 GQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAG 2557



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 52/224 (23%), Positives = 85/224 (37%), Gaps = 38/224 (16%)

Query: 287  EGAREIVCNVTLGGERREARENLTVFSFLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTL 346
            E + E VC  T      + +  LTV+  + P V   +    +   V +S +AG  V +  
Sbjct: 1044 EESGEYVCTATNTAGYAKRKVQLTVY--VRPRVFGDQRGLSQDKPVEISVLAGEEVTLPC 1101

Query: 347  D-------------GVPAAAPGQP-------AQLQLNATESDDGRSFFCSATLEVDGEFL 386
            +                  +P  P         +++  T + D   + C AT  + G   
Sbjct: 1102 EVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVAT-NIAGNV- 1159

Query: 387  HRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYPELRCLKEGSSREV-- 444
                +V+L V   PKI R   P+HLK +   R  + C A+G P P +   K GS+  V  
Sbjct: 1160 --TQAVKLNVHVPPKIQRG--PKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDG 1215

Query: 445  ------PVGIPFFVNVTHN--GTYQCQASSSRGKYTLVVVMDIE 480
                  P G       T +  G Y C A++  G     + + ++
Sbjct: 1216 EHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQ 1259



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 43/192 (22%), Positives = 77/192 (40%), Gaps = 29/192 (15%)

Query: 305  ARENLTVFSFLGPIV--NLSEPTAHE---GSTVTVSCMAGARVQVTL----DGVPAAAPG 355
            A ++  V  ++ P++  NL+ P   +     ++T+ C A       L    DGVP  A  
Sbjct: 1627 AEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKAND 1686

Query: 356  Q------PAQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQ 409
                     +L++ + +  D   + C AT  V GE   +    ++ VL  P I+      
Sbjct: 1687 NIRIEAGGKKLEIMSAQEIDRGQYICVAT-SVAGE---KEIKYEVDVLVPPAIEGGDETS 1742

Query: 410  HLKWKDKTRHVLQCQARGNPYPELRCLKEGSSREVPVGIPFFVN----------VTHNGT 459
            +          L C   G+P P +  LK+G   +   G    +N          V++ G 
Sbjct: 1743 YFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGL 1802

Query: 460  YQCQASSSRGKY 471
            Y+C A+++ G +
Sbjct: 1803 YRCMAANTAGDH 1814



 Score = 37.4 bits (85), Expect = 0.036
 Identities = 68/271 (25%), Positives = 109/271 (40%), Gaps = 45/271 (16%)

Query: 304  EARENLTVFSFLGPIVNLSEPTAH--EGSTVTVSC--MAGARV--------QVTLDGVPA 351
            ++   +TV   + P++ +S   A+  EG  +T+ C  +AG  +           L   P 
Sbjct: 877  QSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPY 936

Query: 352  AAPGQPAQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHL 411
                    L +   +  DG  + C A+  V G   ++ +SV + VL  P I      Q L
Sbjct: 937  ITVRSDGSLHIERVQLQDGGEYTCVAS-NVAGTN-NKTTSVVVHVL--PTIQHGQ--QIL 990

Query: 412  KWKDKTRHVLQCQARGNPYPELRCLKEG-----SSREVPVGIPFFVNVT-----HNGTYQ 461
               +     L C+A GNP P +   K+G     SS +   G    + V       +G Y 
Sbjct: 991  STIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYV 1050

Query: 462  CQASSSRG----KYTLVV-----VMDIEAGSSHFVPVFVAVL------LTLGVVTIVLAL 506
            C A+++ G    K  L V     V   + G S   PV ++VL      L   V ++   +
Sbjct: 1051 CTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPI 1110

Query: 507  MYVFREHQRSGSYHVREESTYLPLTSMQPTE 537
            +   +E Q    +  R   T+LP  SM+ TE
Sbjct: 1111 ITWAKETQLISPFSPRH--TFLPSGSMKITE 1139



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 48/175 (27%), Positives = 69/175 (39%), Gaps = 29/175 (16%)

Query: 320  NLSEPTAHEGSTVTVSCMAGARVQVTL----DGVPAAA-------PGQPAQLQLNATESD 368
            N  + T    S  ++ C A +    T+    DG P  +       PG      LNA E +
Sbjct: 2581 NPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDN 2640

Query: 369  DGRSFFCSATLEVDGEFLHRNSSVQLRV------LYGPKIDRATCPQHLKWKDKTRHVLQ 422
             GR + C AT E      H    V +        L+GP +     P+ +K K      L+
Sbjct: 2641 AGR-YSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS----PKEVKIKVNNTLTLE 2695

Query: 423  CQARGNPYPELRCLKEGSSREVPVGIPFFVNVTHNG-TYQCQAS--SSRGKYTLV 474
            C+A   P   L   K+G     P+     VN+  NG T Q + +  S  G+YT V
Sbjct: 2696 CEAYAIPSASLSWYKDGQ----PLKSDDHVNIAANGHTLQIKEAQISDTGRYTCV 2746



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 20/120 (16%)

Query: 364  ATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQC 423
            AT  D GR + C A + + G          + VL  P I     P  +         L+C
Sbjct: 1421 ATPEDAGR-YSCKA-INIAGT---SQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALEC 1475

Query: 424  QARGNPYPELRCLKEGSSREVPVGIP-----------FFVNVTHN--GTYQCQASSSRGK 470
            Q +G P+P++   K+G  + + +G P              N   N  G YQC  S++ GK
Sbjct: 1476 QVKGTPFPDIHWFKDG--KPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGK 1533



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 44/197 (22%), Positives = 71/197 (36%), Gaps = 30/197 (15%)

Query: 321  LSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQ-----------LQLNATESDD 369
            LSE    +   V + C+A      ++  +    P   AQ           LQ+  T  +D
Sbjct: 1833 LSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLED 1892

Query: 370  GRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNP 429
               + C AT    GE       +QL V   P ++ A    +          L+C+A GNP
Sbjct: 1893 AGRYTCVAT-NAAGE---TQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNP 1948

Query: 430  YPELRCLKEGSSREVPVGIPFF----------VNVTHNGTYQCQASSSRGKYTLVVVMDI 479
             P +   K+         + F             ++  G Y+C A +S G   L   + +
Sbjct: 1949 VPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008

Query: 480  E-----AGSSHFVPVFV 491
                  +GS++ V V V
Sbjct: 2009 HVAPSISGSNNMVAVVV 2025



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 49/194 (25%), Positives = 73/194 (37%), Gaps = 46/194 (23%)

Query: 308  NLTVFS--FLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAA-----PGQPAQL 360
            NL VF+   +   +   E T  +GS+ +++C+         DG PA +      GQP  L
Sbjct: 3427 NLQVFAPPNMDNSMGTEEITVLKGSSTSMACIT--------DGTPAPSMAWLRDGQPLGL 3478

Query: 361  -------------QLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATC 407
                         QL   E++D   + C A+ E      H      L+VL  P I+ +  
Sbjct: 3479 DAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKH----FILKVLEPPHINGSEE 3534

Query: 408  PQHLKWKDKTRHVLQCQARGNPYPELRCLKEGSSREVP------------VGIPFFVNVT 455
             + +         L C A G P P++  +K+G  R +P            V       V 
Sbjct: 3535 HEEISVIVNNPLELTCIASGIPAPKMTWMKDG--RPLPQTDQVQTLGGGEVLRISTAQVE 3592

Query: 456  HNGTYQCQASSSRG 469
              G Y C ASS  G
Sbjct: 3593 DTGRYTCLASSPAG 3606



 Score = 29.6 bits (65), Expect = 7.4
 Identities = 62/320 (19%), Positives = 113/320 (35%), Gaps = 36/320 (11%)

Query: 205  VNTSAPRQLRTFVLPVTPPRLVAP-RFLEVETSWPVD--CTLDGLFPASEAQVYLALGDQ 261
            VN +  +Q    +    PP ++   + + V  S  V+  C  D + P +    +L  G  
Sbjct: 2086 VNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPT--LTWLKDGHP 2143

Query: 262  MLNATVMNHGDTLTATATATARADQEGAREIVCNVTLGGERREARENLTVFSFLGPIVNL 321
            +L    ++  +  +      A+    G          G   +    N+ V   +G    L
Sbjct: 2144 LLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDEL 2203

Query: 322  SEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAP------------GQPAQLQLNATESDD 369
            ++ T  EG+ +++ C +       L      +P                QLQ++  E  D
Sbjct: 2204 TQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSD 2263

Query: 370  GRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRA-TCPQHLKWKDKTRHVLQCQARGN 428
               + C A+  V G          L+V   P I  + + P  +         L+C+ +G 
Sbjct: 2264 AALYSCVAS-NVAGT---AKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGI 2319

Query: 429  PYPELRCLKEGSSREVPVGIPFF----------VNVTHNGTYQCQASSSRG----KYTLV 474
            P P +  +K+G       G+             ++V+  G Y C A +  G    KY L 
Sbjct: 2320 PPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLS 2379

Query: 475  VVMDIEAGSSHFVPVFVAVL 494
            V        +H  P  ++V+
Sbjct: 2380 VHAPPSIIGNHRSPENISVV 2399



 Score = 29.3 bits (64), Expect = 9.7
 Identities = 40/147 (27%), Positives = 56/147 (38%), Gaps = 14/147 (9%)

Query: 333  TVSCMAGARVQVTLDGVPAAAPGQPAQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSV 392
            TV+ M      +   GV     G   QL+ N   SD GR + C A + V G     +   
Sbjct: 2323 TVTWMKDGHPLIKAKGVEILDEGHILQLK-NIHVSDTGR-YVCVA-VNVAGM---TDKKY 2376

Query: 393  QLRVLYGPKI-DRATCPQHLKWKDKTRHVLQCQARGNPYPELRCLKEGSSREVPVGIPFF 451
             L V   P I      P+++   +K    L C+A G P P +   K+G     PV +   
Sbjct: 2377 DLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDG----WPVSLSNS 2432

Query: 452  VNVTHNG---TYQCQASSSRGKYTLVV 475
            V +   G             G+YT VV
Sbjct: 2433 VRILSGGRMLRLMQTTMEDAGQYTCVV 2459


>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
           sapiens]
          Length = 442

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 53/194 (27%), Positives = 79/194 (40%), Gaps = 33/194 (17%)

Query: 306 RENLTVFSFLGP----IVNLSEPTAHEGSTVTVSCMAGARVQVT----------LDGVPA 351
           +E+ T  + L P    ++++ + TA EG  + V+C A A    T          L G   
Sbjct: 132 QESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSE 191

Query: 352 AAPGQP-----AQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQ--LRVLYGPKID- 403
                      +QL L   + DDG    C    +V+   +  N   Q  L V Y P++  
Sbjct: 192 VEEWSDMYTVTSQLMLKVHKEDDGVPVIC----QVEHPAVTGNLQTQRYLEVQYKPQVHI 247

Query: 404 RATCPQHLKWKDKTRHVLQCQARGNPYPEL----RCLKEGSSREVPVGIPFFVN---VTH 456
           + T P     ++     L C+A G P P +    R   E     V  G   F+N    T 
Sbjct: 248 QMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTD 307

Query: 457 NGTYQCQASSSRGK 470
           NGTY+C+AS+  GK
Sbjct: 308 NGTYRCEASNIVGK 321


>gi|40255013 carcinoembryonic antigen-related cell adhesion molecule
           6 (non-specific cross reacting antigen) [Homo sapiens]
          Length = 344

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 40/147 (27%), Positives = 63/147 (42%), Gaps = 8/147 (5%)

Query: 360 LQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRH 419
           L L + + +D  S+ C           +R+  V L VLYGP       P    ++     
Sbjct: 200 LTLLSVKRNDAGSYECEIQNPASA---NRSDPVTLNVLYGPD-GPTISPSKANYRPGENL 255

Query: 420 VLQCQARGNPYPELRCLKEGSSREVPVGIPFFVNVTHN--GTYQCQA-SSSRGKYTLVVV 476
            L C A  NP  +      G+ ++    + F  N+T N  G+Y CQA +S+ G     V 
Sbjct: 256 NLSCHAASNPPAQYSWFINGTFQQSTQEL-FIPNITVNNSGSYMCQAHNSATGLNRTTVT 314

Query: 477 MDIEAGSSHFVPVFVAVLLTLGVVTIV 503
           M   +GS+  +     V +T+GV+  V
Sbjct: 315 MITVSGSAPVLSAVATVGITIGVLARV 341


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 73/299 (24%), Positives = 109/299 (36%), Gaps = 47/299 (15%)

Query: 206  NTSAPRQLRTFVLPVTPPRLVAPRFLEVETSWPVD------CTLDGLFPASEA------Q 253
            N+S   QL   V    PP++  PR    + S   D      C   G  P +         
Sbjct: 1052 NSSQDLQLEVHV----PPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQP 1107

Query: 254  VYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVCNVTLGGERREARENLTVFS 313
            V   LG Q+ N     H +   A  T       E       N+    ER+     L    
Sbjct: 1108 VGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAE-------NLAGRAERKFELSVLVPPE 1160

Query: 314  FLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQ----------LQLN 363
             +G +  L+  TA   S +T+ C A       +       P  P +          L++ 
Sbjct: 1161 LIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMT 1220

Query: 364  ATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQC 423
             T+  D   + C A+ E  GE   RN SV+  VL  P I+     + +K  D     L C
Sbjct: 1221 QTQEQDSGLYSCLASNEA-GE-ARRNFSVE--VLVPPSIENEDLEEVIKVLDGQTAHLMC 1276

Query: 424  QARGNPYPELRCLKEG-------SSREVPVGIPFFV---NVTHNGTYQCQASSSRGKYT 472
               G+P P+L   K+G       +    P G+   V   N++  G Y C A+++ G+ T
Sbjct: 1277 NVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKT 1335



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 57/221 (25%), Positives = 77/221 (34%), Gaps = 24/221 (10%)

Query: 263  LNATVMNHGDTLTATATATARADQEGAREIVCNVTLGGERREARENLTVFSFLGPIVNLS 322
            L+   + HG   T   +    AD  G    V     G   R     + V   L P+   +
Sbjct: 2165 LSQRTLLHGSGHTLRISKVQLADA-GIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQN 2223

Query: 323  EPTAHEGSTVTVSCMAGA----RVQVTLDGVPAAAPG--QPAQLQLNATESDDGRSFFCS 376
            +     GS V + C A       V    DG P  +    Q   LQL A  + D  ++ C 
Sbjct: 2224 DVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCV 2283

Query: 377  ATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYPELRCL 436
            A  E      H     QL V+  P I+ +  P  L         L C A+G P P +   
Sbjct: 2284 AVSEAGEARRH----FQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWH 2339

Query: 437  KEG--------SSREVPVGIPFFVNVTHNGTYQCQASSSRG 469
            K+G        +SR   V     + V   G Y C A S  G
Sbjct: 2340 KDGQALTRLENNSRATRV-----LRVRDAGLYTCLAESPAG 2375



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 69/294 (23%), Positives = 115/294 (39%), Gaps = 41/294 (13%)

Query: 206  NTSAPRQLRTFVLPVTPPRLVAPRFLE--VETSWPVDCTLDGLFPASEAQVYLALGDQML 263
            N +   +LR  +    PPR+  P  L   V  + PV  T +     S   ++L  G+ + 
Sbjct: 769  NVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVS 828

Query: 264  NA-----TVMNHGDTLTATATATARADQEGAREIVCNVTLGGERREARENLTVF-SFLGP 317
             A      V   G  LT    A+ARA   G    V    +G +R++    + +  S LG 
Sbjct: 829  PAGTPGLQVFPGGRVLTL---ASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGE 885

Query: 318  IVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQP----------AQLQLNATES 367
             +N+S   A+E  +V + C + A     L       P +P          A LQ++  + 
Sbjct: 886  ELNVSV-VANE--SVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADV 942

Query: 368  DDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARG 427
             D   + C A  +      H N +V +  ++ P  +  T    L  ++     L C+ RG
Sbjct: 943  WDAGHYTCEALNQAGRSEKHYNLNVWVAPVF-PLRESHT----LTVREGHPTSLSCECRG 997

Query: 428  NPYPELRCLKEGS---------SREVPVGIPFFV---NVTHNGTYQCQASSSRG 469
             P+P++   K+G               VG   ++    +   GTY C+ S+  G
Sbjct: 998  VPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVG 1051



 Score = 37.0 bits (84), Expect = 0.047
 Identities = 39/140 (27%), Positives = 55/140 (39%), Gaps = 20/140 (14%)

Query: 347  DGVPAAAPGQPAQLQ-----LNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPK 401
            DG+P        QLQ     ++ TE DD   + C A  E+          V + VL    
Sbjct: 3064 DGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVA-----KKVVILVLQSAP 3118

Query: 402  IDRATCPQHLKWKDKTRHVLQCQARGNPYPELRCLKEGSS-------REVPVGIPFFVNV 454
            + +   PQ +  +      L+CQA G P P +  L+ G         R +P G  +  NV
Sbjct: 3119 VFQVE-PQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENV 3177

Query: 455  THN--GTYQCQASSSRGKYT 472
                 GTY C A +  G  T
Sbjct: 3178 ETGDAGTYDCVAHNLLGSAT 3197



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 44/157 (28%), Positives = 64/157 (40%), Gaps = 21/157 (13%)

Query: 359 QLQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTR 418
           QLQL   +S D   + C A+  V         + +L V   P I+ A    ++      R
Sbjct: 366 QLQLGRAQSSDAGVYTCKASNAVGAA----EKATRLDVYVPPTIEGAGGRPYVVKAVAGR 421

Query: 419 HV-LQCQARGNPYPELRCLKEG----SSREVPVGIPFFV------NVTHNGTYQCQASSS 467
            V L+C ARG+P P L    EG     S E  +     V          +G Y C ASS 
Sbjct: 422 PVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSP 481

Query: 468 RGKYTLVVVMDIEAGSSHFVPVFVAVLLTLGVVTIVL 504
            G+  L   ++++      VP  + V   LG VT ++
Sbjct: 482 AGEAVLQYSVEVQ------VPPQLLVAEGLGQVTTIV 512



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 10/59 (16%)

Query: 421 LQCQARGNPYPELRCLKEGSSREVPVGIPF----------FVNVTHNGTYQCQASSSRG 469
           L CQA G+P P ++ L+ G   E   G+             V + H+G + CQA++  G
Sbjct: 518 LPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAG 576



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 75/347 (21%), Positives = 120/347 (34%), Gaps = 71/347 (20%)

Query: 117  PERVELAPLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAVEEPAEVTAT 176
            P  + L P  P +       L C  + G+P+ ++T     W ++      +E  +  T  
Sbjct: 2311 PTELSLTPGAPME-------LLCDAQ-GTPQPNIT-----WHKDGQALTRLENNSRATR- 2356

Query: 177  VLASRDDHGAPFSCRTELDMQPQGLGLFVNTSAPRQL-----RTFVLPVTPPRLVAPRFL 231
            VL  RD     ++C  E           V   AP  +       FV+ + P +LV    +
Sbjct: 2357 VLRVRD--AGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSV 2414

Query: 232  EVETSWPVDCTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGARE 291
            E E +  +    DG+    +A        + L    ++  D+   + TA   A   G+  
Sbjct: 2415 EAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAA---GSTS 2471

Query: 292  IVCNVTLGGERREARENLTVFSFLGPIVNLSEPTAHEGS-TVTVSCMAGARVQVTLDGVP 350
            +   V +                       + PT   G   V VS    A +    DGVP
Sbjct: 2472 VAFRVEIH----------------------TVPTIRSGPPAVNVSVNQTALLPCQADGVP 2509

Query: 351  AAA-----------PGQP-------AQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSV 392
            A             P  P         L++    + D   + C A+     +   R+   
Sbjct: 2510 APLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRD--- 2566

Query: 393  QLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYPELRCLKEG 439
             LRVL  P I  A  P +L     T  +L C+A G+P P +   K+G
Sbjct: 2567 -LRVLEPPAI--APSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDG 2610



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 58/233 (24%), Positives = 91/233 (39%), Gaps = 39/233 (16%)

Query: 261  QMLNATVMNHGDTLTATATATARADQEGAREIVCNVT-LGGERREARENLTVFSFLGPIV 319
            Q+L A + + G      A A     +     ++   T LGG    A E +TV +   PI 
Sbjct: 1311 QVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTV-TVNNPIS 1369

Query: 320  NLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAA-------PGQPAQLQLNATESDDGRS 372
             + E  A     +T             DG P  A       PG      LNA + D G+ 
Sbjct: 1370 LICEALAFPSPNITWM----------KDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQ- 1418

Query: 373  FFCSATLEVDGEFLHRNSSVQLRVLYGPKIDR-----ATCPQHLKWKDKTRHVLQCQARG 427
            + C  T E+ GE +    +  + VL  P I +         + +K K  +   L+C++  
Sbjct: 1419 YTCVVTNEL-GEAV---KNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESWA 1474

Query: 428  NPYPELRCLKEG-----SSREVPVGIPFFV-----NVTHNGTYQCQASSSRGK 470
             P P +R  K+G     SSR   +G    +      V+ +G Y C A++  G+
Sbjct: 1475 VPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGE 1527



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 28/102 (27%), Positives = 39/102 (38%), Gaps = 4/102 (3%)

Query: 346 LDGVPAAAPGQPAQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRA 405
           L G P  A  +   L L +    D   + C AT EV       +   +L V   P I   
Sbjct: 45  LHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGST----SRRAKLVVYVPPSIRED 100

Query: 406 TCPQHLKWKDKTRHVLQCQARGNPYPELRCLKEGSSREVPVG 447
               ++         L+C A G P PE+  LK+     VP+G
Sbjct: 101 GRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLG 142



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 6/82 (7%)

Query: 360  LQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKI--DRATCPQHLKWKDKT 417
            LQ+    +++   + C A+ EV  ++LH     +L VL  P I  D     + +     +
Sbjct: 1615 LQIPLVRAENAGRYSCKASNEVGEDWLH----YELLVLTPPVILGDTEELVEEVTVNASS 1670

Query: 418  RHVLQCQARGNPYPELRCLKEG 439
               LQC A GNP P +  L+ G
Sbjct: 1671 TVSLQCPALGNPVPTISWLQNG 1692



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 40/179 (22%), Positives = 68/179 (37%), Gaps = 36/179 (20%)

Query: 324  PTAHEGSTVTVSCMAGARVQVTLD--GVPA------------------AAPGQPAQLQLN 363
            PT     T TVS +AG+ + +T D  GVPA                      +  +LQL+
Sbjct: 1933 PTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLS 1992

Query: 364  ATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQC 423
              +     ++ C A    +           + VL  P+I  +   +     +     L C
Sbjct: 1993 RLQPAQAGTYTCVA----ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDC 2048

Query: 424  QARGNPYPELRCLKEGSSREVPVG--IPFFVN----------VTHNGTYQCQASSSRGK 470
            +A G P P++  LK+GS     +G  + F+++           +  G Y C A +  G+
Sbjct: 2049 EADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGE 2107



 Score = 29.3 bits (64), Expect = 9.7
 Identities = 53/219 (24%), Positives = 85/219 (38%), Gaps = 28/219 (12%)

Query: 282  ARADQEGAREIVCNVTLGGERREARENLTVFSFLGPIVN--LSEPTAHEGSTVTVSCMAG 339
            A A  E A   +C           +  L V   + P++   L + +  EGS   + C A 
Sbjct: 2814 AHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ--VPPVIENGLPDLSTTEGSHAFLPCKAR 2871

Query: 340  ARVQVTL----DGVPAA-APG----QPA-QLQLNATESDDGRSFFCSATLEVDGEFLHRN 389
               +  +    DG P + A G    QP+ +L +   E  D  ++ C+A   V        
Sbjct: 2872 GSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVG----RAR 2927

Query: 390  SSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYPEL------RCLKEGSSRE 443
              V L +L  P        + L+  D  R  L+C ARG+P P +      R + EG S +
Sbjct: 2928 RRVHLTILVLPVFTTLPGDRSLRLGD--RLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQ 2985

Query: 444  VPVGI--PFFVNVTHNGTYQCQASSSRGKYTLVVVMDIE 480
                      V+   +GTY C A +  G+   V  + ++
Sbjct: 2986 DGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 3024


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 73/299 (24%), Positives = 109/299 (36%), Gaps = 47/299 (15%)

Query: 206  NTSAPRQLRTFVLPVTPPRLVAPRFLEVETSWPVD------CTLDGLFPASEA------Q 253
            N+S   QL   V    PP++  PR    + S   D      C   G  P +         
Sbjct: 2243 NSSQDLQLEVHV----PPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQP 2298

Query: 254  VYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVCNVTLGGERREARENLTVFS 313
            V   LG Q+ N     H +   A  T       E       N+    ER+     L    
Sbjct: 2299 VGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAE-------NLAGRAERKFELSVLVPPE 2351

Query: 314  FLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQ----------LQLN 363
             +G +  L+  TA   S +T+ C A       +       P  P +          L++ 
Sbjct: 2352 LIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMT 2411

Query: 364  ATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQC 423
             T+  D   + C A+ E  GE   RN SV+  VL  P I+     + +K  D     L C
Sbjct: 2412 QTQEQDSGLYSCLASNEA-GE-ARRNFSVE--VLVPPSIENEDLEEVIKVLDGQTAHLMC 2467

Query: 424  QARGNPYPELRCLKEG-------SSREVPVGIPFFV---NVTHNGTYQCQASSSRGKYT 472
               G+P P+L   K+G       +    P G+   V   N++  G Y C A+++ G+ T
Sbjct: 2468 NVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKT 2526



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 57/221 (25%), Positives = 77/221 (34%), Gaps = 24/221 (10%)

Query: 263  LNATVMNHGDTLTATATATARADQEGAREIVCNVTLGGERREARENLTVFSFLGPIVNLS 322
            L+   + HG   T   +    AD  G    V     G   R     + V   L P+   +
Sbjct: 3356 LSQRTLLHGSGHTLRISKVQLADA-GIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQN 3414

Query: 323  EPTAHEGSTVTVSCMAGA----RVQVTLDGVPAAAPG--QPAQLQLNATESDDGRSFFCS 376
            +     GS V + C A       V    DG P  +    Q   LQL A  + D  ++ C 
Sbjct: 3415 DVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCV 3474

Query: 377  ATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYPELRCL 436
            A  E      H     QL V+  P I+ +  P  L         L C A+G P P +   
Sbjct: 3475 AVSEAGEARRH----FQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWH 3530

Query: 437  KEG--------SSREVPVGIPFFVNVTHNGTYQCQASSSRG 469
            K+G        +SR   V     + V   G Y C A S  G
Sbjct: 3531 KDGQALTRLENNSRATRV-----LRVRDAGLYTCLAESPAG 3566



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 69/294 (23%), Positives = 115/294 (39%), Gaps = 41/294 (13%)

Query: 206  NTSAPRQLRTFVLPVTPPRLVAPRFLE--VETSWPVDCTLDGLFPASEAQVYLALGDQML 263
            N +   +LR  +    PPR+  P  L   V  + PV  T +     S   ++L  G+ + 
Sbjct: 1960 NVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVS 2019

Query: 264  NA-----TVMNHGDTLTATATATARADQEGAREIVCNVTLGGERREARENLTVF-SFLGP 317
             A      V   G  LT    A+ARA   G    V    +G +R++    + +  S LG 
Sbjct: 2020 PAGTPGLQVFPGGRVLTL---ASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGE 2076

Query: 318  IVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQP----------AQLQLNATES 367
             +N+S   A+E  +V + C + A     L       P +P          A LQ++  + 
Sbjct: 2077 ELNVSV-VANE--SVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADV 2133

Query: 368  DDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARG 427
             D   + C A  +      H N +V +  ++ P  +  T    L  ++     L C+ RG
Sbjct: 2134 WDAGHYTCEALNQAGHSEKHYNLNVWVAPVF-PLRESHT----LTVREGHPTSLSCECRG 2188

Query: 428  NPYPELRCLKEGS---------SREVPVGIPFFV---NVTHNGTYQCQASSSRG 469
             P+P++   K+G               VG   ++    +   GTY C+ S+  G
Sbjct: 2189 VPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVG 2242



 Score = 37.0 bits (84), Expect = 0.047
 Identities = 39/140 (27%), Positives = 55/140 (39%), Gaps = 20/140 (14%)

Query: 347  DGVPAAAPGQPAQLQ-----LNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPK 401
            DG+P        QLQ     ++ TE DD   + C A  E+          V + VL    
Sbjct: 4255 DGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVA-----KKVVILVLQSAP 4309

Query: 402  IDRATCPQHLKWKDKTRHVLQCQARGNPYPELRCLKEGSS-------REVPVGIPFFVNV 454
            + +   PQ +  +      L+CQA G P P +  L+ G         R +P G  +  NV
Sbjct: 4310 VFQVE-PQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENV 4368

Query: 455  THN--GTYQCQASSSRGKYT 472
                 GTY C A +  G  T
Sbjct: 4369 ETGDAGTYDCVAHNLLGSAT 4388



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 44/157 (28%), Positives = 64/157 (40%), Gaps = 21/157 (13%)

Query: 359  QLQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTR 418
            QLQL   +S D   + C A+  V         + +L V   P I+ A    ++      R
Sbjct: 1557 QLQLGRAQSSDAGVYTCKASNAVGAA----EKATRLDVYVPPTIEGAGGRPYVVKAVAGR 1612

Query: 419  HV-LQCQARGNPYPELRCLKEG----SSREVPVGIPFFV------NVTHNGTYQCQASSS 467
             V L+C ARG+P P L    EG     S E  +     V          +G Y C ASS 
Sbjct: 1613 PVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSP 1672

Query: 468  RGKYTLVVVMDIEAGSSHFVPVFVAVLLTLGVVTIVL 504
             G+  L   ++++      VP  + V   LG VT ++
Sbjct: 1673 AGEAVLQYSVEVQ------VPPQLLVAEGLGQVTTIV 1703



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 10/59 (16%)

Query: 421  LQCQARGNPYPELRCLKEGSSREVPVGIPF----------FVNVTHNGTYQCQASSSRG 469
            L CQA G+P P ++ L+ G   E   G+             V + H+G + CQA++  G
Sbjct: 1709 LPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAG 1767



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 75/347 (21%), Positives = 120/347 (34%), Gaps = 71/347 (20%)

Query: 117  PERVELAPLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAVEEPAEVTAT 176
            P  + L P  P +       L C  + G+P+ ++T     W ++      +E  +  T  
Sbjct: 3502 PTELSLTPGAPME-------LLCDAQ-GTPQPNIT-----WHKDGQALTRLENNSRATR- 3547

Query: 177  VLASRDDHGAPFSCRTELDMQPQGLGLFVNTSAPRQL-----RTFVLPVTPPRLVAPRFL 231
            VL  RD     ++C  E           V   AP  +       FV+ + P +LV    +
Sbjct: 3548 VLRVRD--AGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSV 3605

Query: 232  EVETSWPVDCTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGARE 291
            E E +  +    DG+    +A        + L    ++  D+   + TA   A   G+  
Sbjct: 3606 EAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAA---GSTS 3662

Query: 292  IVCNVTLGGERREARENLTVFSFLGPIVNLSEPTAHEGS-TVTVSCMAGARVQVTLDGVP 350
            +   V +                       + PT   G   V VS    A +    DGVP
Sbjct: 3663 VAFRVEIH----------------------TVPTIRSGPPAVNVSVNQTALLPCQADGVP 3700

Query: 351  AAA-----------PGQP-------AQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSV 392
            A             P  P         L++    + D   + C A+     +   R+   
Sbjct: 3701 APLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRD--- 3757

Query: 393  QLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYPELRCLKEG 439
             LRVL  P I  A  P +L     T  +L C+A G+P P +   K+G
Sbjct: 3758 -LRVLEPPAI--APSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDG 3801



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 33/117 (28%), Positives = 50/117 (42%), Gaps = 16/117 (13%)

Query: 360  LQLNATESDDGRSFFCSATLEVDGEFLHR---NSSVQLRVLYGPKIDRATCPQHLKWKDK 416
            L+L   +  D   + C+A+    G   HR      V  +V  GP++ +    + L     
Sbjct: 1084 LRLAQVQVGDSGHYECTASNPA-GSASHRYVLGVQVPPQVQPGPRVLKVLVGEALD---- 1138

Query: 417  TRHVLQCQARGNPYPELRCLKEG--SSREVPVGIPFF--VNVTHNGTYQCQASSSRG 469
                L C A GNP P+L   K+G       P G   F  +  +  G Y+C+AS+S G
Sbjct: 1139 ----LNCVAEGNPEPQLSWSKDGVVLQGRGPQGSVHFAAIRTSDAGRYRCEASNSAG 1191



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 36/136 (26%), Positives = 52/136 (38%), Gaps = 13/136 (9%)

Query: 321  LSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAP--GQPA-------QLQLNATESDDGR 371
            L E  A E +++        + QVT    P++ P  GQP         L L +    D  
Sbjct: 1215 LLERVAGENASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSG 1274

Query: 372  SFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYP 431
             + C AT EV       +   +L V   P I       ++         L+C A G P P
Sbjct: 1275 DYECQATNEVGST----SRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVP 1330

Query: 432  ELRCLKEGSSREVPVG 447
            E+  LK+     VP+G
Sbjct: 1331 EIVWLKDAQLVGVPLG 1346



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 58/233 (24%), Positives = 91/233 (39%), Gaps = 39/233 (16%)

Query: 261  QMLNATVMNHGDTLTATATATARADQEGAREIVCNVT-LGGERREARENLTVFSFLGPIV 319
            Q+L A + + G      A A     +     ++   T LGG    A E +TV +   PI 
Sbjct: 2502 QVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTV-TVNNPIS 2560

Query: 320  NLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAA-------PGQPAQLQLNATESDDGRS 372
             + E  A     +T             DG P  A       PG      LNA + D G+ 
Sbjct: 2561 LICEALAFPSPNITWM----------KDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQ- 2609

Query: 373  FFCSATLEVDGEFLHRNSSVQLRVLYGPKIDR-----ATCPQHLKWKDKTRHVLQCQARG 427
            + C  T E+ GE +    +  + VL  P I +         + +K K  +   L+C++  
Sbjct: 2610 YTCVVTNEL-GEAV---KNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESWA 2665

Query: 428  NPYPELRCLKEG-----SSREVPVGIPFFV-----NVTHNGTYQCQASSSRGK 470
             P P +R  K+G     SSR   +G    +      V+ +G Y C A++  G+
Sbjct: 2666 VPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGE 2718



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 6/82 (7%)

Query: 360  LQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKI--DRATCPQHLKWKDKT 417
            LQ+    +++   + C A+ EV  ++LH     +L VL  P I  D     + +     +
Sbjct: 2806 LQIPLVRAENAGRYSCKASNEVGEDWLH----YELLVLTPPVILGDTEELVEEVTVNASS 2861

Query: 418  RHVLQCQARGNPYPELRCLKEG 439
               LQC A GNP P +  L+ G
Sbjct: 2862 TVSLQCPALGNPVPTISWLQNG 2883



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 40/179 (22%), Positives = 68/179 (37%), Gaps = 36/179 (20%)

Query: 324  PTAHEGSTVTVSCMAGARVQVTLD--GVPA------------------AAPGQPAQLQLN 363
            PT     T TVS +AG+ + +T D  GVPA                      +  +LQL+
Sbjct: 3124 PTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLS 3183

Query: 364  ATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQC 423
              +     ++ C A    +           + VL  P+I  +   +     +     L C
Sbjct: 3184 RLQPAQAGTYTCVA----ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDC 3239

Query: 424  QARGNPYPELRCLKEGSSREVPVG--IPFFVN----------VTHNGTYQCQASSSRGK 470
            +A G P P++  LK+GS     +G  + F+++           +  G Y C A +  G+
Sbjct: 3240 EADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGE 3298



 Score = 29.3 bits (64), Expect = 9.7
 Identities = 53/219 (24%), Positives = 85/219 (38%), Gaps = 28/219 (12%)

Query: 282  ARADQEGAREIVCNVTLGGERREARENLTVFSFLGPIVN--LSEPTAHEGSTVTVSCMAG 339
            A A  E A   +C           +  L V   + P++   L + +  EGS   + C A 
Sbjct: 4005 AHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ--VPPVIENGLPDLSTTEGSHAFLPCKAR 4062

Query: 340  ARVQVTL----DGVPAA-APG----QPA-QLQLNATESDDGRSFFCSATLEVDGEFLHRN 389
               +  +    DG P + A G    QP+ +L +   E  D  ++ C+A   V        
Sbjct: 4063 GSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVG----RAR 4118

Query: 390  SSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYPEL------RCLKEGSSRE 443
              V L +L  P        + L+  D  R  L+C ARG+P P +      R + EG S +
Sbjct: 4119 RRVHLTILVLPVFTTLPGDRSLRLGD--RLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQ 4176

Query: 444  VPVGI--PFFVNVTHNGTYQCQASSSRGKYTLVVVMDIE 480
                      V+   +GTY C A +  G+   V  + ++
Sbjct: 4177 DGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 4215


>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3783

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 73/299 (24%), Positives = 109/299 (36%), Gaps = 47/299 (15%)

Query: 206  NTSAPRQLRTFVLPVTPPRLVAPRFLEVETSWPVD------CTLDGLFPASEA------Q 253
            N+S   QL   V    PP++  PR    + S   D      C   G  P +         
Sbjct: 961  NSSQDLQLEVHV----PPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQP 1016

Query: 254  VYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVCNVTLGGERREARENLTVFS 313
            V   LG Q+ N     H +   A  T       E       N+    ER+     L    
Sbjct: 1017 VGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAE-------NLAGRAERKFELSVLVPPE 1069

Query: 314  FLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQ----------LQLN 363
             +G +  L+  TA   S +T+ C A       +       P  P +          L++ 
Sbjct: 1070 LIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMT 1129

Query: 364  ATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQC 423
             T+  D   + C A+ E  GE   RN SV+  VL  P I+     + +K  D     L C
Sbjct: 1130 QTQEQDSGLYSCLASNEA-GE-ARRNFSVE--VLVPPSIENEDLEEVIKVLDGQTAHLMC 1185

Query: 424  QARGNPYPELRCLKEG-------SSREVPVGIPFFV---NVTHNGTYQCQASSSRGKYT 472
               G+P P+L   K+G       +    P G+   V   N++  G Y C A+++ G+ T
Sbjct: 1186 NVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKT 1244



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 57/221 (25%), Positives = 77/221 (34%), Gaps = 24/221 (10%)

Query: 263  LNATVMNHGDTLTATATATARADQEGAREIVCNVTLGGERREARENLTVFSFLGPIVNLS 322
            L+   + HG   T   +    AD  G    V     G   R     + V   L P+   +
Sbjct: 2074 LSQRTLLHGSGHTLRISKVQLADA-GIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQN 2132

Query: 323  EPTAHEGSTVTVSCMAGA----RVQVTLDGVPAAAPG--QPAQLQLNATESDDGRSFFCS 376
            +     GS V + C A       V    DG P  +    Q   LQL A  + D  ++ C 
Sbjct: 2133 DVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCV 2192

Query: 377  ATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYPELRCL 436
            A  E      H     QL V+  P I+ +  P  L         L C A+G P P +   
Sbjct: 2193 AVSEAGEARRH----FQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWH 2248

Query: 437  KEG--------SSREVPVGIPFFVNVTHNGTYQCQASSSRG 469
            K+G        +SR   V     + V   G Y C A S  G
Sbjct: 2249 KDGQALTRLENNSRATRV-----LRVRDAGLYTCLAESPAG 2284



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 70/294 (23%), Positives = 116/294 (39%), Gaps = 41/294 (13%)

Query: 206 NTSAPRQLRTFVLPVTPPRLVAPRFLE--VETSWPVDCTLDGLFPASEAQVYLALGDQML 263
           N +   +LR  +    PPR+  P  L   V  + PV  T +     S   ++L  G+ + 
Sbjct: 678 NVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVS 737

Query: 264 NA-----TVMNHGDTLTATATATARADQEGAREIVCNVTLGGERREARENLTVF-SFLGP 317
            A      V   G  LT    A+ARA   G    V    +G +R++    + +  S LG 
Sbjct: 738 PAGTPGLQVFPGGRVLTL---ASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGE 794

Query: 318 IVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQP----------AQLQLNATES 367
            +N+S   A+E  +V + C + A     L       P +P          A LQ++  + 
Sbjct: 795 ELNVSV-VANE--SVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADV 851

Query: 368 DDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARG 427
            D   + C A  +      H N +V +  ++ P  +  T    ++    TR  L C+ RG
Sbjct: 852 WDAGHYTCEALNQAGHSEKHYNLNVWVAPVF-PLRESHTLT--VREGHPTR--LSCECRG 906

Query: 428 NPYPELRCLKEGS---------SREVPVGIPFFV---NVTHNGTYQCQASSSRG 469
            P+P++   K+G               VG   ++    +   GTY C+ S+  G
Sbjct: 907 VPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVG 960



 Score = 36.6 bits (83), Expect = 0.061
 Identities = 39/140 (27%), Positives = 54/140 (38%), Gaps = 20/140 (14%)

Query: 347  DGVPAAAPGQPAQLQ-----LNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPK 401
            DG+P        QLQ     +  TE DD   + C A  E+          V + VL    
Sbjct: 2973 DGLPLRGSHLRHQLQNGSLTIRRTERDDAGRYQCLAENEMGVA-----KKVVILVLQSAP 3027

Query: 402  IDRATCPQHLKWKDKTRHVLQCQARGNPYPELRCLKEGSS-------REVPVGIPFFVNV 454
            + +   PQ +  +      L+CQA G P P +  L+ G         R +P G  +  NV
Sbjct: 3028 VFQVE-PQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENV 3086

Query: 455  THN--GTYQCQASSSRGKYT 472
                 GTY C A +  G  T
Sbjct: 3087 ETGDAGTYDCVAHNLLGSAT 3106



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 44/157 (28%), Positives = 64/157 (40%), Gaps = 21/157 (13%)

Query: 359 QLQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTR 418
           QLQL   +S D   + C A+  V         + +L V   P I+ A    ++      R
Sbjct: 275 QLQLGRAQSSDAGVYTCKASNAVGAA----EKATRLDVYVPPTIEGAGGRPYVVKAVAGR 330

Query: 419 HV-LQCQARGNPYPELRCLKEG----SSREVPVGIPFFV------NVTHNGTYQCQASSS 467
            V L+C ARG+P P L    EG     S E  +     V          +G Y C ASS 
Sbjct: 331 PVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSP 390

Query: 468 RGKYTLVVVMDIEAGSSHFVPVFVAVLLTLGVVTIVL 504
            G+  L   ++++      VP  + V   LG VT ++
Sbjct: 391 AGEAVLQYSVEVQ------VPPQLLVAEGLGQVTTIV 421



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 10/59 (16%)

Query: 421 LQCQARGNPYPELRCLKEGSSREVPVGIPF----------FVNVTHNGTYQCQASSSRG 469
           L CQA G+P P ++ L+ G   E   G+             V + H+G + CQA++  G
Sbjct: 427 LPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAG 485



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 75/347 (21%), Positives = 120/347 (34%), Gaps = 71/347 (20%)

Query: 117  PERVELAPLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAVEEPAEVTAT 176
            P  + L P  P +       L C  + G+P+ ++T     W ++      +E  +  T  
Sbjct: 2220 PTELSLTPGAPME-------LLCDAQ-GTPQPNIT-----WHKDGQALTRLENNSRATR- 2265

Query: 177  VLASRDDHGAPFSCRTELDMQPQGLGLFVNTSAPRQL-----RTFVLPVTPPRLVAPRFL 231
            VL  RD     ++C  E           V   AP  +       FV+ + P +LV    +
Sbjct: 2266 VLRVRD--AGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSV 2323

Query: 232  EVETSWPVDCTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGARE 291
            E E +  +    DG+    +A        + L    ++  D+   + TA   A   G+  
Sbjct: 2324 EAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAA---GSTS 2380

Query: 292  IVCNVTLGGERREARENLTVFSFLGPIVNLSEPTAHEGS-TVTVSCMAGARVQVTLDGVP 350
            +   V +                       + PT   G   V VS    A +    DGVP
Sbjct: 2381 VAFRVEIH----------------------TVPTIRSGPPAVNVSVNQTALLPCQADGVP 2418

Query: 351  AAA-----------PGQP-------AQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSV 392
            A             P  P         L++    + D   + C A+     +   R+   
Sbjct: 2419 APLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRD--- 2475

Query: 393  QLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYPELRCLKEG 439
             LRVL  P I  A  P +L     T  +L C+A G+P P +   K+G
Sbjct: 2476 -LRVLEPPAI--APSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDG 2519



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 58/233 (24%), Positives = 91/233 (39%), Gaps = 39/233 (16%)

Query: 261  QMLNATVMNHGDTLTATATATARADQEGAREIVCNVT-LGGERREARENLTVFSFLGPIV 319
            Q+L A + + G      A A     +     ++   T LGG    A E +TV +   PI 
Sbjct: 1220 QVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTV-TVNNPIS 1278

Query: 320  NLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAA-------PGQPAQLQLNATESDDGRS 372
             + E  A     +T             DG P  A       PG      LNA + D G+ 
Sbjct: 1279 LICEALAFPSPNITWM----------KDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQ- 1327

Query: 373  FFCSATLEVDGEFLHRNSSVQLRVLYGPKIDR-----ATCPQHLKWKDKTRHVLQCQARG 427
            + C  T E+ GE +    +  + VL  P I +         + +K K  +   L+C++  
Sbjct: 1328 YTCVVTNEL-GEAV---KNYHVEVLIPPSISKDDPLAEVGVKEVKTKVNSTLTLECESWA 1383

Query: 428  NPYPELRCLKEG-----SSREVPVGIPFFV-----NVTHNGTYQCQASSSRGK 470
             P P +R  K+G     SSR   +G    +      V+ +G Y C A++  G+
Sbjct: 1384 VPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGE 1436



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 6/82 (7%)

Query: 360  LQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKI--DRATCPQHLKWKDKT 417
            LQ+    +++   + C A+ EV  ++LH     +L VL  P I  D     + +     +
Sbjct: 1524 LQIPLVRAENAGRYSCKASNEVGEDWLH----YELLVLTPPVILGDTEELVEEVTVNASS 1579

Query: 418  RHVLQCQARGNPYPELRCLKEG 439
               LQC A GNP P +  L+ G
Sbjct: 1580 TVSLQCPALGNPVPTISWLQNG 1601



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 40/179 (22%), Positives = 68/179 (37%), Gaps = 36/179 (20%)

Query: 324  PTAHEGSTVTVSCMAGARVQVTLD--GVPA------------------AAPGQPAQLQLN 363
            PT     T TVS +AG+ + +T D  GVPA                      +  +LQL+
Sbjct: 1842 PTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLS 1901

Query: 364  ATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQC 423
              +     ++ C A    +           + VL  P+I  +   +     +     L C
Sbjct: 1902 RLQPAQAGTYTCVA----ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDC 1957

Query: 424  QARGNPYPELRCLKEGSSREVPVG--IPFFVN----------VTHNGTYQCQASSSRGK 470
            +A G P P++  LK+GS     +G  + F+++           +  G Y C A +  G+
Sbjct: 1958 EADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGE 2016



 Score = 29.3 bits (64), Expect = 9.7
 Identities = 53/219 (24%), Positives = 85/219 (38%), Gaps = 28/219 (12%)

Query: 282  ARADQEGAREIVCNVTLGGERREARENLTVFSFLGPIVN--LSEPTAHEGSTVTVSCMAG 339
            A A  E A   +C           +  L V   + P++   L + +  EGS   + C A 
Sbjct: 2723 AHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ--VPPVIENGLPDLSTTEGSHAFLPCKAR 2780

Query: 340  ARVQVTL----DGVPAA-APG----QPA-QLQLNATESDDGRSFFCSATLEVDGEFLHRN 389
               +  +    DG P + A G    QP+ +L +   E  D  ++ C+A   V        
Sbjct: 2781 GSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVG----RAR 2836

Query: 390  SSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYPEL------RCLKEGSSRE 443
              V L +L  P        + L+  D  R  L+C ARG+P P +      R + EG S +
Sbjct: 2837 RRVHLTILVLPVFTTLPGDRSLRLGD--RLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQ 2894

Query: 444  VPVGI--PFFVNVTHNGTYQCQASSSRGKYTLVVVMDIE 480
                      V+   +GTY C A +  G+   V  + ++
Sbjct: 2895 DGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 2933


>gi|61742797 basal cell adhesion molecule isoform 2 precursor [Homo
           sapiens]
          Length = 588

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 48/206 (23%), Positives = 83/206 (40%), Gaps = 23/206 (11%)

Query: 328 EGSTVTVSCMAGARVQVTLDGVPAAAP---------GQPAQLQLNATESDDGRSFFCSAT 378
           EG  +++   + A V  ++ G+P  A          G    L L++   D   ++ C A+
Sbjct: 368 EGKVLSLPLNSSAVVNCSVHGLPTPALRWTKDSTPLGDGPMLSLSSITFDSNGTYVCEAS 427

Query: 379 LEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHL--KWKDKTRHVLQCQARGNPYPELRCL 436
           L      L R  +  L V   P++  A         W++     L C ARG+P P+L   
Sbjct: 428 LPTV-PVLSRTQNFTLLVQGSPELKTAEIEPKADGSWREGDEVTLICSARGHPDPKLSWS 486

Query: 437 KEGSSREVP-------VGIPFFVNVT---HNGTYQCQASSSRG-KYTLVVVMDIEAGSSH 485
           + G S   P       V     + VT         C+AS+  G K  +     +   +S 
Sbjct: 487 QLGGSPAEPIPGRQGWVSSSLTLKVTSALSRDGISCEASNPHGNKRHVFHFGTVSPQTSQ 546

Query: 486 FVPVFVAVLLTLGVVTIVLALMYVFR 511
                +AV +++G++ +V+A+ Y  R
Sbjct: 547 AGVAVMAVAVSVGLLLLVVAVFYCVR 572



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 27/117 (23%), Positives = 47/117 (40%), Gaps = 10/117 (8%)

Query: 337 MAGARVQVTLDGVPAAAP----GQPAQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSV 392
           M G+ +QVT+      +P        +L L   +  D R + C       G      ++ 
Sbjct: 83  MQGSELQVTMHDTRGRSPPYQLDSQGRLVLAEAQVGDERDYVCVVRAGAAGT---AEATA 139

Query: 393 QLRVLYGPKIDRATCPQHLK--WKDKTRHVLQCQAR-GNPYPELRCLKEGSSREVPV 446
           +L V   P+    +  +      +D  + +  C +R GNP P++   + G   EVPV
Sbjct: 140 RLNVFAKPEATEVSPNKGTLSVMEDSAQEIATCNSRNGNPAPKITWYRNGQRLEVPV 196


>gi|31543106 basal cell adhesion molecule isoform 1 precursor [Homo
           sapiens]
          Length = 628

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 48/206 (23%), Positives = 83/206 (40%), Gaps = 23/206 (11%)

Query: 328 EGSTVTVSCMAGARVQVTLDGVPAAAP---------GQPAQLQLNATESDDGRSFFCSAT 378
           EG  +++   + A V  ++ G+P  A          G    L L++   D   ++ C A+
Sbjct: 368 EGKVLSLPLNSSAVVNCSVHGLPTPALRWTKDSTPLGDGPMLSLSSITFDSNGTYVCEAS 427

Query: 379 LEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHL--KWKDKTRHVLQCQARGNPYPELRCL 436
           L      L R  +  L V   P++  A         W++     L C ARG+P P+L   
Sbjct: 428 LPTV-PVLSRTQNFTLLVQGSPELKTAEIEPKADGSWREGDEVTLICSARGHPDPKLSWS 486

Query: 437 KEGSSREVP-------VGIPFFVNVT---HNGTYQCQASSSRG-KYTLVVVMDIEAGSSH 485
           + G S   P       V     + VT         C+AS+  G K  +     +   +S 
Sbjct: 487 QLGGSPAEPIPGRQGWVSSSLTLKVTSALSRDGISCEASNPHGNKRHVFHFGTVSPQTSQ 546

Query: 486 FVPVFVAVLLTLGVVTIVLALMYVFR 511
                +AV +++G++ +V+A+ Y  R
Sbjct: 547 AGVAVMAVAVSVGLLLLVVAVFYCVR 572



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 27/117 (23%), Positives = 47/117 (40%), Gaps = 10/117 (8%)

Query: 337 MAGARVQVTLDGVPAAAP----GQPAQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSV 392
           M G+ +QVT+      +P        +L L   +  D R + C       G      ++ 
Sbjct: 83  MQGSELQVTMHDTRGRSPPYQLDSQGRLVLAEAQVGDERDYVCVVRAGAAGT---AEATA 139

Query: 393 QLRVLYGPKIDRATCPQHLK--WKDKTRHVLQCQAR-GNPYPELRCLKEGSSREVPV 446
           +L V   P+    +  +      +D  + +  C +R GNP P++   + G   EVPV
Sbjct: 140 RLNVFAKPEATEVSPNKGTLSVMEDSAQEIATCNSRNGNPAPKITWYRNGQRLEVPV 196


>gi|4827022 contactin 2 precursor [Homo sapiens]
          Length = 1040

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 44/175 (25%), Positives = 72/175 (41%), Gaps = 29/175 (16%)

Query: 326 AHEGSTVTVSC-----MAGARVQVTLDGVPAAAPGQ--------PAQLQLNATESDDGRS 372
           AHEG  V + C       G   +  L+  P   P             L +  T + D  +
Sbjct: 145 AHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGN 204

Query: 373 FFCSATLEVD-------GEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQA 425
           + C AT  +D        +F   N + +   L+ P I +A  P         +  L+C A
Sbjct: 205 YSCLATSHMDFSTKSVFSKFAQLNLAAEDTRLFAPSI-KARFPAETYALVGQQVTLECFA 263

Query: 426 RGNPYPELRCLK-------EGSSREVPVGIPFFVNVTHNGTYQCQASSSRGKYTL 473
            GNP P ++  K       + ++ E  + IP  V+    GTY+C+A +S+G+ T+
Sbjct: 264 FGNPVPRIKWRKVDGSLSPQWTTAEPTLQIPS-VSFEDEGTYECEAENSKGRDTV 317



 Score = 29.3 bits (64), Expect = 9.7
 Identities = 43/185 (23%), Positives = 72/185 (38%), Gaps = 32/185 (17%)

Query: 322 SEPTAHEGSTVTVSCMAGARVQVTL-----DGV--PAAAPGQPAQLQLNATESDDGRSFF 374
           +E  A  G  VT+ C A       +     DG   P     +P  LQ+ +   +D  ++ 
Sbjct: 247 AETYALVGQQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPT-LQIPSVSFEDEGTYE 305

Query: 375 CSATLE-----VDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNP 429
           C A        V G  + +     L+V+   + D  +   +L+W         C A G P
Sbjct: 306 CEAENSKGRDTVQGRIIVQAQPEWLKVISDTEADIGS---NLRWG--------CAAAGKP 354

Query: 430 YPELRCLKEG------SSREVPVGIPFF--VNVTHNGTYQCQASSSRGKYTLVVVMDIEA 481
            P +R L+ G      +  EV  G   F  +++  +G YQC A +  G       + ++A
Sbjct: 355 RPTVRWLRNGEPLASQNRVEVLAGDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQA 414

Query: 482 GSSHF 486
            +  F
Sbjct: 415 LAPDF 419


>gi|157168355 CD22 molecule [Homo sapiens]
          Length = 847

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 61/254 (24%), Positives = 100/254 (39%), Gaps = 39/254 (15%)

Query: 240 DCTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVCNVTLG 299
           + T DG  P+ + +V   LGD+  N T+  H   L  +     R + +            
Sbjct: 78  ESTKDGKVPSEQKRVQF-LGDKNKNCTLSIHPVHLNDSGQLGLRMESKT----------- 125

Query: 300 GERREARENLTVFSFLGPIVNLSEPTAHEGSTVTVSCMAG-------ARVQVTLDGVP-- 350
            E+   R +L V     P      P   E   VT++C+          ++Q  L+GVP  
Sbjct: 126 -EKWMERIHLNVSERPFPPHIQLPPEIQESQEVTLTCLLNFSCYGYPIQLQWLLEGVPMR 184

Query: 351 -AAAPGQP---------AQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGP 400
            AA              ++L+ +   S  G+   C    + DG+FL  N +VQL V + P
Sbjct: 185 QAAVTSTSLTIKSVFTRSELKFSPQWSHHGKIVTCQLQ-DADGKFLS-NDTVQLNVKHTP 242

Query: 401 KIDRATCPQHLKWKDKTRHVLQCQ-ARGNP-YPELRCLKEGSSREVPVGIPF---FVNVT 455
           K++    P     ++     + C+ +  NP Y  +  LK+G+S +           V   
Sbjct: 243 KLEIKVTPSDAIVREGDSVTMTCEVSSSNPEYTTVSWLKDGTSLKKQNTFTLNLREVTKD 302

Query: 456 HNGTYQCQASSSRG 469
            +G Y CQ S+  G
Sbjct: 303 QSGKYCCQVSNDVG 316



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 27/120 (22%), Positives = 50/120 (41%), Gaps = 7/120 (5%)

Query: 355 GQPAQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWK 414
           G+ +QL  ++   +D  S+ C     +       + +  L VLY P+  R +     +  
Sbjct: 551 GKESQLNFDSISPEDAGSYSCWVNNSIGQT---ASKAWTLEVLYAPRRLRVSMSPGDQVM 607

Query: 415 DKTRHVLQCQARGNPYPELRCLKEGSSREVPVGIPFF----VNVTHNGTYQCQASSSRGK 470
           +     L C++  NP        + +++ +P          V V H+G Y CQ ++S GK
Sbjct: 608 EGKSATLTCESDANPPVSHYTWFDWNNQSLPYHSQKLRLEPVKVQHSGAYWCQGTNSVGK 667


>gi|21686977 cell adhesion molecule 4 [Homo sapiens]
          Length = 388

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 62/239 (25%), Positives = 92/239 (38%), Gaps = 34/239 (14%)

Query: 317 PIVNLSEPTAHEGSTVTVSCMAGA----------RVQVTLDGVPAAAPGQP-----AQLQ 361
           P+V + E  A EG  V +SC+             R +  L GV ++          + ++
Sbjct: 127 PVVEVREQ-AVEGGEVELSCLVPRSRPAATLRWYRDRKELKGVSSSQENGKVWSVASTVR 185

Query: 362 LNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVL 421
                 DDG    C A  +       + +   L V Y P   R    Q +  +  T  VL
Sbjct: 186 FRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLDVQYSPTA-RIHASQAVVREGDTL-VL 243

Query: 422 QCQARGNPYPELRCLKEGSS----REVPVG----IPFFVNVTHNGTYQCQASSSRGK--- 470
            C   GNP P       G+     R   VG    +P  V+   NGTY C+AS+  G    
Sbjct: 244 TCAVTGNPRPNQIRWNRGNESLPERAEAVGETLTLPGLVSAD-NGTYTCEASNKHGHARA 302

Query: 471 -YTLVVV---MDIEAGSSHFVPVFVAVLLTLGVVTIVLALMYVFREHQRSGSYHVREES 525
            Y LVV      +EA +S    +   +L  L  + I + +  V+   ++ GSY   E S
Sbjct: 303 LYVLVVYDPGAVVEAQTSVPYAIVGGILALLVFLIICVLVGMVWCSVRQKGSYLTHEAS 361


>gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens]
          Length = 1349

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 35/122 (28%), Positives = 54/122 (44%), Gaps = 10/122 (8%)

Query: 358 AQLQLNATESDDGRSFFCSAT-LEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDK 416
           A L+L    S+D   + C    L+   +  H  S V L +   P     T PQ+++ K+ 
Sbjct: 96  ASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPTFTE-TPPQYIEAKEG 154

Query: 417 TRHVLQCQARGNPYPELRCLKEGS------SREVPVGIPFFVNVTH--NGTYQCQASSSR 468
               + C A GNP P +  LKEG+        +V  G     +V+    G Y C+A S +
Sbjct: 155 GSITMTCTAFGNPKPIVTWLKEGTLLGASGKYQVSDGSLTVTSVSREDRGAYTCRAYSIQ 214

Query: 469 GK 470
           G+
Sbjct: 215 GE 216


>gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens]
          Length = 869

 Score = 38.9 bits (89), Expect = 0.012
 Identities = 40/129 (31%), Positives = 59/129 (45%), Gaps = 16/129 (12%)

Query: 362 LNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVL 421
           L+  +SDDG  + C+A   V G      S   L+V   PKI R   P ++K  +  + VL
Sbjct: 87  LSVEDSDDG-IYCCTANNGVGGAV---ESCGALQVKMKPKITRP--PINVKIIEGLKAVL 140

Query: 422 QCQARGNPYPELRCLKEGSSREVPVGIPFFVNVT---HN------GTYQCQASSSRG-KY 471
            C   GNP P +  +K  S       I    + +   HN      G Y+C A +S G  Y
Sbjct: 141 PCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAY 200

Query: 472 TLVVVMDIE 480
           + VV +++E
Sbjct: 201 SKVVKLEVE 209


>gi|145275174 kin of IRRE-like 2 isoform c [Homo sapiens]
          Length = 708

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 69/278 (24%), Positives = 98/278 (35%), Gaps = 29/278 (10%)

Query: 208 SAPRQLRTFVLPVTPPRLVAPRFLEVETSWPVDCTLDGLFPASEAQVYLALGDQML---- 263
           S P QL   V P  P  L  P  + +    P + T      A      L   D +L    
Sbjct: 112 SRPAQLHVLVPPEAPQVLGGPS-VSLVAGVPANLTCRSRGDARPTPELLWFRDGVLLDGA 170

Query: 264 --NATVMNHGD--TLTATATATARADQEGAREIVCNVTLGGERREARENLTVFSFLGPIV 319
             + T++  G   ++ +T T T  +  +GA   VC              +T+     P V
Sbjct: 171 TFHQTLLKEGTPGSVESTLTLTPFSHDDGAT-FVCRARSQALPTGRDTAITLSLQYPPEV 229

Query: 320 NLSEP--TAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPA------QLQLNATESDDGR 371
            LS    T  EG  V   C A A+  VT  G   A  G P       +L++ A  S    
Sbjct: 230 TLSASPHTVQEGEKVIFLCQATAQPPVT--GYRWAKGGSPVLGARGPRLEVVADASFLTE 287

Query: 372 SFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYP 431
              C    EV       N S  L VL+GP +     P  +   +       C  RGNP P
Sbjct: 288 PVSC----EVSNAVGSANRSTALDVLFGPILQAKPEPVSVDVGEDAS--FSCAWRGNPLP 341

Query: 432 ELRCLKEGSSREVPVGIPF---FVNVTHNGTYQCQASS 466
            +   + G ++ +  G       V     G Y C+A +
Sbjct: 342 RVTWTRRGGAQVLGSGATLRLPSVGPEDAGDYVCRAEA 379


>gi|145275172 kin of IRRE-like 2 isoform b [Homo sapiens]
          Length = 583

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 69/278 (24%), Positives = 98/278 (35%), Gaps = 29/278 (10%)

Query: 208 SAPRQLRTFVLPVTPPRLVAPRFLEVETSWPVDCTLDGLFPASEAQVYLALGDQML---- 263
           S P QL   V P  P  L  P  + +    P + T      A      L   D +L    
Sbjct: 62  SRPAQLHVLVPPEAPQVLGGPS-VSLVAGVPANLTCRSRGDARPTPELLWFRDGVLLDGA 120

Query: 264 --NATVMNHGD--TLTATATATARADQEGAREIVCNVTLGGERREARENLTVFSFLGPIV 319
             + T++  G   ++ +T T T  +  +GA   VC              +T+     P V
Sbjct: 121 TFHQTLLKEGTPGSVESTLTLTPFSHDDGAT-FVCRARSQALPTGRDTAITLSLQYPPEV 179

Query: 320 NLSEP--TAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPA------QLQLNATESDDGR 371
            LS    T  EG  V   C A A+  VT  G   A  G P       +L++ A  S    
Sbjct: 180 TLSASPHTVQEGEKVIFLCQATAQPPVT--GYRWAKGGSPVLGARGPRLEVVADASFLTE 237

Query: 372 SFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYP 431
              C    EV       N S  L VL+GP +     P  +   +       C  RGNP P
Sbjct: 238 PVSC----EVSNAVGSANRSTALDVLFGPILQAKPEPVSVDVGEDAS--FSCAWRGNPLP 291

Query: 432 ELRCLKEGSSREVPVGIPF---FVNVTHNGTYQCQASS 466
            +   + G ++ +  G       V     G Y C+A +
Sbjct: 292 RVTWTRRGGAQVLGSGATLRLPSVGPEDAGDYVCRAEA 329


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,976,230
Number of Sequences: 37866
Number of extensions: 1037704
Number of successful extensions: 3256
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 118
Number of HSP's that attempted gapping in prelim test: 2870
Number of HSP's gapped (non-prelim): 429
length of query: 547
length of database: 18,247,518
effective HSP length: 107
effective length of query: 440
effective length of database: 14,195,856
effective search space: 6246176640
effective search space used: 6246176640
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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