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Search of human proteins with 167234419
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167234419 thyroid hormone receptor associated protein 3
[Homo sapiens]
(955 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167234419 thyroid hormone receptor associated protein 3 [Homo... 1930 0.0
gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Hom... 533 e-151
gi|117938251 BCL2-associated transcription factor 1 isoform 2 [H... 412 e-115
gi|169218320 PREDICTED: similar to BCL2-associated transcription... 402 e-111
gi|239756568 PREDICTED: similar to BCL2-associated transcription... 399 e-111
gi|117938254 BCL2-associated transcription factor 1 isoform 3 [H... 367 e-101
gi|115511057 hypothetical protein LOC256643 [Homo sapiens] 105 3e-22
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 103 1e-21
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 99 1e-20
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 97 5e-20
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 97 5e-20
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 87 7e-17
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 87 1e-16
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 84 5e-16
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 83 1e-15
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 82 2e-15
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 82 3e-15
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 81 4e-15
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 80 1e-14
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 80 1e-14
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 79 2e-14
gi|60097902 filaggrin [Homo sapiens] 79 2e-14
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 79 2e-14
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 79 2e-14
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 79 2e-14
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 76 2e-13
gi|50083281 KIAA1853 protein [Homo sapiens] 72 2e-12
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 72 3e-12
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 72 3e-12
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 71 4e-12
>gi|167234419 thyroid hormone receptor associated protein 3 [Homo
sapiens]
Length = 955
Score = 1930 bits (4999), Expect = 0.0
Identities = 955/955 (100%), Positives = 955/955 (100%)
Query: 1 MSKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNR 60
MSKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNR
Sbjct: 1 MSKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNR 60
Query: 61 ERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSP 120
ERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSP
Sbjct: 61 ERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSP 120
Query: 121 RRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEK 180
RRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEK
Sbjct: 121 RRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEK 180
Query: 181 KSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVS 240
KSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVS
Sbjct: 181 KSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVS 240
Query: 241 ELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQG 300
ELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQG
Sbjct: 241 ELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQG 300
Query: 301 QFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDK 360
QFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDK
Sbjct: 301 QFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDK 360
Query: 361 EQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEK 420
EQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEK
Sbjct: 361 EQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEK 420
Query: 421 KMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPG 480
KMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPG
Sbjct: 421 KMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPG 480
Query: 481 KEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRK 540
KEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRK
Sbjct: 481 KEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRK 540
Query: 541 TSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHS 600
TSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHS
Sbjct: 541 TSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHS 600
Query: 601 NKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKR 660
NKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKR
Sbjct: 601 NKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKR 660
Query: 661 GTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLD 720
GTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLD
Sbjct: 661 GTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLD 720
Query: 721 IERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSS 780
IERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSS
Sbjct: 721 IERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSS 780
Query: 781 SSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARG 840
SSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARG
Sbjct: 781 SSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARG 840
Query: 841 RGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDKWVSRGRG 900
RGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDKWVSRGRG
Sbjct: 841 RGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDKWVSRGRG 900
Query: 901 RGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREEKDNIQPTTE 955
RGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREEKDNIQPTTE
Sbjct: 901 RGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREEKDNIQPTTE 955
>gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Homo
sapiens]
Length = 920
Score = 533 bits (1373), Expect = e-151
Identities = 399/972 (41%), Positives = 537/972 (55%), Gaps = 96/972 (9%)
Query: 10 GSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQ 69
G +SRS S SRS+SRS S SRSRSRS SRK+R SSRSRSR+YS + +R+R + R Y+
Sbjct: 2 GRSNSRSHS-SRSKSRSQSSSRSRSRS--HSRKKRYSSRSRSRTYSRSRSRDRMYSRDYR 58
Query: 70 NRDFRGHNRGYRRPYYFRGRNRGFYPWG--QYNRGGYGNYRSNWQNYRQAYSPRRGRSRS 127
RD+R +NRG RRPY +RGR RG+Y G +Y+RGGY R W N R + SPRRGRSRS
Sbjct: 59 -RDYR-NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGY---RPVW-NRRHSRSPRRGRSRS 112
Query: 128 RSPKRRS-PSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKD 186
RSPKRRS S RSRS SR S +SS RS RSSSSRSSS +S+ SKR+ ++EK++ +
Sbjct: 113 RSPKRRSVSSQRSRSRSRRSYRSS--RSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170
Query: 187 SRPSQAAG-DNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPR 245
P + + ++ E + TF + SES + ++ +G + + SPR
Sbjct: 171 GEPQEESPLKSKSQEEPKDTF------EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPR 224
Query: 246 ERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHG 305
SP SP+ + + S +P+ +T S + +SG+ G +G
Sbjct: 225 --SPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS--GSVGNG 280
Query: 306 SGSLSPSKKSPVG-----KSPPSTGSTYGSSQKEESAAS-----GG---AAYTKRYLEEQ 352
S SPS+ SP+ +SP T + + + E S GG A T ++L+
Sbjct: 281 SSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRF 340
Query: 353 KTENGKDKEQKQTNT-DKEKIKEKGSFSDTGLGDGKMKS----DSFAPKTDSEKPFRGSQ 407
E + + NT DKE KEKGS + G +G+ + D F+ K ++ F S+
Sbjct: 341 TDEESRVFLLDRGNTRDKEASKEKGS--EKGRAEGEWEDQEALDYFSDKESGKQKFNDSE 398
Query: 408 SPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKV-IGANKNQE-- 464
+ D F K + DQ K A + ++ K+ SKV + N+ +
Sbjct: 399 GDDTEETED-----YRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGF 453
Query: 465 -EEKSGKWE--GLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNF 521
EEK+ K + G V P K + EE ++ S KKE + PE+
Sbjct: 454 REEKNYKLKETGYVVERPSTTKDKHKEE-DKNSERITVKKETQS-----------PEQ-- 499
Query: 522 RVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTG-KSSFSITREAQVNVRMDSFDEDL 580
V + K SPP K ++R+K + + P K S + +V ++M D
Sbjct: 500 -VKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDD 558
Query: 581 ARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKE 640
+ L ++R L LVHS KKEQEFRSIF HI+ Q+ +S SE F QHIV++VHHVKE
Sbjct: 559 SNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKE 618
Query: 641 HHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPR 700
+F S+ MTL+ERFT Y K +E + +KSPEIHRRIDISPST RKH E + +
Sbjct: 619 QYFKSAAMTLNERFTSYQK--ATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFK 676
Query: 701 EPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKT 760
E K + K + D DLR DI+RR+ KER +RG S+ SR+SS SR++ EKT K
Sbjct: 677 EENQKGDKKLRCDSADLRHDIDRRR--KERSKERGDSK---GSRESSGSRKQ--EKTPKD 729
Query: 761 HKGSKKQK---KHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTK 817
+K K K KH+R +D SRSSSSS+ S EE + E EE T + K
Sbjct: 730 YKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHE-----MK 784
Query: 818 DFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNN--NNSNNDFQKRNREEEWDPEYTP 875
++ G + G R RGTF FR RGRG RG ++G N NNSN FQKR +EEEWDPEYTP
Sbjct: 785 EYSGFA--GVSRPRGTF-FRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTP 841
Query: 876 KSKKYYLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIE 935
KSKKY+LHDDR+ +G D W RGRGRG F RGRGRF F+KS +SPKW HDK+ G +G +E
Sbjct: 842 KSKKYFLHDDRD-DGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQG-DGIVE 899
Query: 936 DDESGTENREEK 947
D+E EN EEK
Sbjct: 900 DEEETMENNEEK 911
>gi|117938251 BCL2-associated transcription factor 1 isoform 2 [Homo
sapiens]
Length = 869
Score = 412 bits (1059), Expect = e-115
Identities = 347/967 (35%), Positives = 484/967 (50%), Gaps = 137/967 (14%)
Query: 10 GSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQ 69
G +SRS S SRS+SRS S SRSRSRS SRK+R RSRSR+YS + +R+R + R Y+
Sbjct: 2 GRSNSRSHS-SRSKSRSQSSSRSRSRS--HSRKKRY--RSRSRTYSRSRSRDRMYSRDYR 56
Query: 70 NRDFRGHNRGYRRPYYFRGRNRGFYPWG--QYNRGGYGNYRSNWQNYRQAYSPRRGRSRS 127
RD+R +NRG RRPY +RGR RG+Y G +Y+RGGY R W N R + SPRRGRSRS
Sbjct: 57 -RDYR-NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGY---RPVW-NRRHSRSPRRGRSRS 110
Query: 128 RSPKRRS-PSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKD 186
RSPKRRS S RSRS SR S +SS RS RSSSSRSSS +S+ SKR+ ++EK++ +
Sbjct: 111 RSPKRRSVSSQRSRSRSRRSYRSS--RSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 168
Query: 187 SRPSQAAG-DNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPR 245
P + + ++ E + TF + SES + ++ +G + + SPR
Sbjct: 169 GEPQEESPLKSKSQEEPKDTF------EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPR 222
Query: 246 ERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHG 305
SP SP+ + + S +P+ +T S + +SG+ G +G
Sbjct: 223 --SPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS--GSVGNG 278
Query: 306 SGSLSPSKKSPVG-----KSPPSTGSTYGSSQKEESAAS-----GG---AAYTKRYLEEQ 352
S SPS+ SP+ +SP T + + + E S GG A T ++L+
Sbjct: 279 SSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRF 338
Query: 353 KTENGKDKEQKQTNT-DKEKIKEKGSFSDTGLGDGKMKS----DSFAPKTDSEKPFRGSQ 407
E + + NT DKE KEKGS + G +G+ + D F+ K ++ F S+
Sbjct: 339 TDEESRVFLLDRGNTRDKEASKEKGS--EKGRAEGEWEDQEALDYFSDKESGKQKFNDSE 396
Query: 408 SPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKV-IGANKNQE-- 464
+ D F K + DQ K A + ++ K+ SKV + N+ +
Sbjct: 397 GDDTEETED-----YRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGF 451
Query: 465 -EEKSGKWE--GLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNF 521
EEK+ K + G V P K + EE ++ S KKE + PE+
Sbjct: 452 REEKNYKLKETGYVVERPSTTKDKHKEE-DKNSERITVKKETQS-----------PEQ-- 497
Query: 522 RVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTG-KSSFSITREAQVNVRMDSFDEDL 580
V + K SPP K ++R+K + + P K S + +V ++M D
Sbjct: 498 -VKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDD 556
Query: 581 ARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKE 640
+ L ++R L LVHS KKEQEFRSIF HI+ Q+ +S SE F QHIV++VHHVKE
Sbjct: 557 SNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKE 616
Query: 641 HHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPR 700
+F S+ MTL+ERFT Y K +E + +KSPEIHRRIDISPST RKH E + +
Sbjct: 617 QYFKSAAMTLNERFTSYQK--ATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFK 674
Query: 701 EPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKT 760
E K + K + D DLR DI+RR+K ER +RG S+ SR+SS SR K EKT
Sbjct: 675 EENQKGDKKLRCDSADLRHDIDRRRK--ERSKERGDSK---GSRESSGSR-----KQEKT 724
Query: 761 HKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFV 820
K K+ K ++ S H E+ R S++ S ++
Sbjct: 725 PKDYKEYKSYK------------DDSKHK------REQDHSRSSSSSASPSSPSSREEKE 766
Query: 821 GPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKY 880
ER +F+ + +E+ +
Sbjct: 767 SKKER-------------------------------EEEFKTHHEMKEYSGFAGVSRPRG 795
Query: 881 YLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESG 940
HDDR+ +G D W RGRGRG F RGRGRF F+KS +SPKW HDK+ G +G +ED+E
Sbjct: 796 TFHDDRD-DGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQG-DGIVEDEEET 853
Query: 941 TENREEK 947
EN EEK
Sbjct: 854 MENNEEK 860
>gi|169218320 PREDICTED: similar to BCL2-associated transcription
factor 1 isoform 2 [Homo sapiens]
Length = 869
Score = 402 bits (1032), Expect = e-111
Identities = 341/967 (35%), Positives = 479/967 (49%), Gaps = 137/967 (14%)
Query: 10 GSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQ 69
G +SRS S SRS+SRS S SRSRSRS SRK+R RSRSR+YS + +R+R + R Y+
Sbjct: 2 GRSNSRSHS-SRSKSRSQSSSRSRSRS--HSRKKRY--RSRSRTYSRSRSRDRMYSRDYR 56
Query: 70 NRDFRGHNRGYRRPYYFRGRNRGFYPWG--QYNRGGYGNYRSNWQNYRQAYSPRRGRSRS 127
RD+R +NR RRPY +RGR RG+Y G +Y+RGGY R W N R + SPRRGRSRS
Sbjct: 57 -RDYR-NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGY---RPVW-NRRHSRSPRRGRSRS 110
Query: 128 RSPKRRS-PSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKD 186
RSPKRRS S RSRS SR S +SS RS RSSSSRSSS +S+ SKR+ ++EK++ +
Sbjct: 111 RSPKRRSVSSQRSRSRSRRSYRSS--RSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 168
Query: 187 SRPSQAAG-DNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPR 245
P + + ++ E + TF + SES + ++ +G + + SPR
Sbjct: 169 GEPQEESPLKSKSQEEPKDTF------EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPR 222
Query: 246 ERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHG 305
SP SP+ + + S +P+ +T S + +SG+ G +G
Sbjct: 223 --SPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS--GSVGNG 278
Query: 306 SGSLSPSKKSPVG-----KSPPSTGSTYGSSQKEESAAS-----GG---AAYTKRYLEEQ 352
S SPS+ SP+ +SP T + + + E S GG A T ++L+
Sbjct: 279 SSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRF 338
Query: 353 KTENGKDKEQKQTNT-DKEKIKEKGSFSDTGLGDGKMKS----DSFAPKTDSEKPFRGSQ 407
E + + NT DKE KEKGS + G +G+ + D F+ K ++ F S+
Sbjct: 339 TDEESRVFLLDRGNTRDKEASKEKGS--EKGRAEGEWEDQEALDYFSDKESGKQKFNDSE 396
Query: 408 SPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKV-IGANKNQE-- 464
+ D F K + DQ K A + ++ K+ SKV + N+ +
Sbjct: 397 GDDTEETED-----YRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGF 451
Query: 465 -EEKSGKWE--GLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNF 521
EEK+ K + G V P K + EE ++ S KKE + PE+
Sbjct: 452 REEKNDKHKETGYVVERPSTTKDKHKEE-DKNSERITVKKETQS-----------PEQ-- 497
Query: 522 RVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTG-KSSFSITREAQVNVRMDSFDEDL 580
V + K SPP K ++R+K + + P K S + +V ++M D
Sbjct: 498 -VKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDD 556
Query: 581 ARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKE 640
+ L ++R L LVHS KKEQEFRSIF HI+ Q+ +S SE F QHIV++VHHVKE
Sbjct: 557 SNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKE 616
Query: 641 HHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPR 700
+F S+ MTL ERFT Y K +E + +KSPEIHRRIDISPST RK E + +
Sbjct: 617 QYFKSAAMTLSERFTSYQK--ATEEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFK 674
Query: 701 EPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKT 760
E K + K + D DLR DI+ R+K ER +RG S+ S +SR S R EKT K
Sbjct: 675 EENQKGDKKLRCDSADLRHDIDHRRK--ERSKERGDSKGSRESRGS-----RKQEKTPKD 727
Query: 761 HKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFV 820
+K YK+ Y ++++ + E S +
Sbjct: 728 YK--------------------------EYKS--YKDDSKHKREQDHSLSSSSSASPS-- 757
Query: 821 GPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKY 880
PS R ++ +F+ + +E+ +
Sbjct: 758 SPSSREEKESK----------------------KEREEEFKTHHEMKEYSGFAGVSRPRG 795
Query: 881 YLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESG 940
HDDR+ +G D W RGRGRG F RGRGRF F+KS +SPKW HDK+ G +G +ED+E
Sbjct: 796 TFHDDRD-DGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDKYQG-DGIVEDEEET 853
Query: 941 TENREEK 947
EN EEK
Sbjct: 854 MENNEEK 860
>gi|239756568 PREDICTED: similar to BCL2-associated transcription
factor 1 [Homo sapiens]
Length = 869
Score = 399 bits (1024), Expect = e-111
Identities = 340/967 (35%), Positives = 478/967 (49%), Gaps = 137/967 (14%)
Query: 10 GSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQ 69
G +SRS S SRS+SRS S SRSRSRS SRK+R RSRSR+YS + +R+R + R Y+
Sbjct: 2 GRSNSRSHS-SRSKSRSQSSSRSRSRS--HSRKKRY--RSRSRTYSRSRSRDRMYSRDYR 56
Query: 70 NRDFRGHNRGYRRPYYFRGRNRGFYPWG--QYNRGGYGNYRSNWQNYRQAYSPRRGRSRS 127
RD+R +NR RRPY +RGR RG+Y G +Y+RGGY R W N R + SPRRGRSRS
Sbjct: 57 -RDYR-NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGY---RPVW-NRRHSRSPRRGRSRS 110
Query: 128 RSPKRRS-PSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKD 186
RSPKRRS S RSRS SR S +SS RS RSSSSRSSS +S+ SKR+ ++EK++ +
Sbjct: 111 RSPKRRSVSSQRSRSRSRRSYRSS--RSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 168
Query: 187 SRPSQAAG-DNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPR 245
+ + ++ E + TF + +SES + ++ G + + SPR
Sbjct: 169 GELQEESPLKSKSQEEPKDTF------EHDSSESIDEFNKSSATCGDIWPGLSAYDXSPR 222
Query: 246 ERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHG 305
SP SP+ + + S +P+ +T S + +SG+ G +G
Sbjct: 223 --SPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS--GSVGNG 278
Query: 306 SGSLSPSKKSPVG-----KSPPSTGSTYGSSQKEESAAS-----GG---AAYTKRYLEEQ 352
S SPS+ SP+ +SP T + + + E S GG A T ++L+
Sbjct: 279 SSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRF 338
Query: 353 KTENGKDKEQKQTNT-DKEKIKEKGSFSDTGLGDGKMKS----DSFAPKTDSEKPFRGSQ 407
E + + NT DKE KEKGS + G +G+ + D F+ K ++ F S+
Sbjct: 339 TDEESRVFLLDRGNTRDKEASKEKGS--EKGRAEGEWEDQEALDYFSDKESGKQKFNDSE 396
Query: 408 SPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKV-IGANKNQE-- 464
+ D F K + DQ K A + ++ K+ SKV + N+ +
Sbjct: 397 GDDTEETED-----YRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGF 451
Query: 465 -EEKSGKWE--GLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNF 521
EEK+ K + G V P K + EE ++ S KKE + PE+
Sbjct: 452 REEKNDKHKETGYVVERPSTTKDKHKEE-DKNSERITVKKETQS-----------PEQ-- 497
Query: 522 RVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTG-KSSFSITREAQVNVRMDSFDEDL 580
V + K SPP K ++R+K + + P K S + +V ++M D
Sbjct: 498 -VKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDD 556
Query: 581 ARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKE 640
+ L ++R L LVHS KKEQEFRSIF HI+ Q+ +S SE F QHIV++VHHVKE
Sbjct: 557 SNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKE 616
Query: 641 HHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPR 700
+F S+ MTL ERFT Y K +E + +KSPEIHRRIDISPST RK E + +
Sbjct: 617 QYFKSAAMTLSERFTSYQK--ATEEHSTRQKSPEIHRRIDISPSTLRKDTRLAGEERVFK 674
Query: 701 EPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKT 760
E K + K + D DLR DI+ R+K ER +RG S+ S +SR S R EKT K
Sbjct: 675 EENQKGDKKLRCDSADLRHDIDHRRK--ERSKERGDSKGSRESRGS-----RKQEKTPKD 727
Query: 761 HKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFV 820
+K YK+ Y ++++ + E S +
Sbjct: 728 YK--------------------------EYKS--YKDDSKHKREQDHSLSSSSSASPS-- 757
Query: 821 GPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKY 880
PS R ++ +F+ + +E+ +
Sbjct: 758 SPSSREEKESK----------------------KEREEEFKTHHEMKEYSGFAGVSRPRG 795
Query: 881 YLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESG 940
HDDR+ +G D W RGRGRG F RGRGRF F+KS +SPKW HDK+ G +G +ED+E
Sbjct: 796 TFHDDRD-DGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDKYQG-DGIVEDEEET 853
Query: 941 TENREEK 947
EN EEK
Sbjct: 854 MENNEEK 860
>gi|117938254 BCL2-associated transcription factor 1 isoform 3 [Homo
sapiens]
Length = 747
Score = 367 bits (942), Expect = e-101
Identities = 297/834 (35%), Positives = 396/834 (47%), Gaps = 106/834 (12%)
Query: 123 GRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRS---SSNHSRVESSKRKSAKE 179
GRS SRS RS S RS+S SR+ +S S + R SS SRS S + SR R ++
Sbjct: 2 GRSNSRSHSSRSKS-RSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
Query: 180 KKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAV 239
+++ RP G +G + GG G
Sbjct: 61 YRNNRGMRRPYGYRGRGRG------YYQGG---------------------GGRYHRGGY 93
Query: 240 SELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQ 299
+ R S RSPR SP S S S S Y+S +
Sbjct: 94 RPVWNRRHS--------------RSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSS--R 137
Query: 300 GQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKD 359
S S SP KSPV K GS +K+ A G +E+ K
Sbjct: 138 SPRSSSSRSSSPYSKSPVSKRR-------GSQEKQTKKAEGEP-------QEESPLKSKS 183
Query: 360 KEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFE 419
+E+ + + + + F+ + G D + + + R SP
Sbjct: 184 QEEPKDTFEHDPSESIDEFNKSSATSG----DIWPGLSAYDNSPRSPHSPSPIATPPSQS 239
Query: 420 KKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPP 479
+D K+ S + S +G N S ++ P
Sbjct: 240 SSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVG---NGSSRYSPSQNSPIHHIP 296
Query: 480 GKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPR 539
+ KT + ++ P + E RG+ S F P+ + TA KS PP
Sbjct: 297 SRRSPAKT--IAPQNAP---RDESRGRSS------FYPDGGDQETAKTGKFLKS--PPLH 343
Query: 540 KTSESRDKLGAKGDFPTG-KSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLV 598
K ++R+K + + P K S + +V ++M D + L ++R L LV
Sbjct: 344 KNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLV 403
Query: 599 HSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYL 658
HS KKEQEFRSIF HI+ Q+ +S SE F QHIV++VHHVKE +F S+ MTL+ERFT Y
Sbjct: 404 HSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQ 463
Query: 659 KRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLR 718
K +E + +KSPEIHRRIDISPST RKH E + +E K + K + D DLR
Sbjct: 464 K--ATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLR 521
Query: 719 LDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQK---KHRRARD 775
DI+RR+K ER +RG S+ SR+SS SR++ EKT K +K K K KH+R +D
Sbjct: 522 HDIDRRRK--ERSKERGDSK---GSRESSGSRKQ--EKTPKDYKEYKSYKDDSKHKREQD 574
Query: 776 RSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQ 835
SRSSSSS+ S EE + E EE T + K++ G + G R RGTF
Sbjct: 575 HSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEM-----KEYSGFA--GVSRPRGTF- 626
Query: 836 FRARGRGWGRGNYSGNNN--NNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDK 893
FR RGRG RG ++G N NNSN FQKR +EEEWDPEYTPKSKKY+LHDDR+ +G D
Sbjct: 627 FRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRD-DGVDY 685
Query: 894 WVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREEK 947
W RGRGRG F RGRGRF F+KS +SPKW HDK+ G +G +ED+E EN EEK
Sbjct: 686 WAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQG-DGIVEDEEETMENNEEK 738
Score = 189 bits (479), Expect = 1e-47
Identities = 195/639 (30%), Positives = 301/639 (47%), Gaps = 73/639 (11%)
Query: 10 GSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQ 69
G +SRS S SRS+SRS S SRSRSRS SRK+R SSRSRSR+YS + +R+R + R Y+
Sbjct: 2 GRSNSRSHS-SRSKSRSQSSSRSRSRS--HSRKKRYSSRSRSRTYSRSRSRDRMYSRDYR 58
Query: 70 NRDFRGHNRGYRRPYYFRGRNRGFYP--WGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRS 127
RD+R +NRG RRPY +RGR RG+Y G+Y+RGG YR W N R + SPRRGRSRS
Sbjct: 59 -RDYR-NNRGMRRPYGYRGRGRGYYQGGGGRYHRGG---YRPVW-NRRHSRSPRRGRSRS 112
Query: 128 RSPKRRS-PSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKD 186
RSPKRRS S RSRS SR S +SS RS RSSSSRSSS +S+ SKR+ ++EK++ +
Sbjct: 113 RSPKRRSVSSQRSRSRSRRSYRSS--RSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 170
Query: 187 SRPSQAAG-DNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPR 245
P + + ++ E + TF + SES + ++ +G + + SP
Sbjct: 171 GEPQEESPLKSKSQEEPKDTF------EHDPSESIDEFNKSSATSGDIWPGLSAYDNSP- 223
Query: 246 ERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHG 305
RSP SP+ + + S +P+ +T S + +SG+ G +G
Sbjct: 224 -RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS--GSVGNG 280
Query: 306 SGSLSPSKKSPV-----GKSPPSTGSTYGSSQKEESAAS-----GG---AAYTKRYLEEQ 352
S SPS+ SP+ +SP T + + + E S GG A T ++L+
Sbjct: 281 SSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSP 340
Query: 353 KTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQS---- 408
D +K T ++ ++ K SD+ + K+K + P DS +P ++
Sbjct: 341 PLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKM-APVPLDDSNRPASLTKDRLLA 399
Query: 409 -------PKRYKLRDDFEK-KMADFHKEEMDDQDKD--------KAKGRKESEFDDEPKF 452
K + R F+ K+ K + + K + K + +F
Sbjct: 400 STLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERF 459
Query: 453 MSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGH 512
S ++ +KS + + P ++ EE F E ++K D+ R +
Sbjct: 460 TSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSAD 519
Query: 513 RGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTGKS--SFSITREAQVN 570
++ + + +E+ S R++S SR + D+ KS S + Q +
Sbjct: 520 LRHDIDRRRK----ERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDH 575
Query: 571 VRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRS 609
R S + PS +E K ++E+EF++
Sbjct: 576 SRSSSSSASPSSPSSREEKESK--------KEREEEFKT 606
Score = 38.9 bits (89), Expect = 0.023
Identities = 46/195 (23%), Positives = 73/195 (37%), Gaps = 13/195 (6%)
Query: 764 SKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPS 823
S + R++ RS+SSS S SHS K + Y+ + R S + + R+ ++D+
Sbjct: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRK-KRYSSRSRSRTYSRSR-SRDRMYSRDYRRDY 61
Query: 824 ERGGGRARGTFQFRARGRGW---GRGNYSGNNN----NNSNNDFQKRNREEEWDPEYTPK 876
G R + +R RGRG+ G G Y N ++ +R R P+
Sbjct: 62 RNNRGMRR-PYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
Query: 877 SKKYYLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIED 936
S + R S + R + P + R+ S + K GE E E
Sbjct: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQ--TKKAEGEPQE-ES 177
Query: 937 DESGTENREEKDNIQ 951
E KD +
Sbjct: 178 PLKSKSQEEPKDTFE 192
Score = 35.8 bits (81), Expect = 0.20
Identities = 76/356 (21%), Positives = 117/356 (32%), Gaps = 53/356 (14%)
Query: 19 ASRSRSRSFSK---SRSRSRSLSRSRKRRLSSRSRSRSYSPA---HNRERNHPRVYQNRD 72
AS+S S SF + S + ++ R SY A H+ + P +++ D
Sbjct: 424 ASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRID 483
Query: 73 FRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRG-RSRSRSPK 131
R+ G R F + N+ G R + + R RR RS+ R
Sbjct: 484 ISPST--LRKHTRLAGEERVFK---EENQKGDKKLRCDSADLRHDIDRRRKERSKERGDS 538
Query: 132 RRSPSPRSRSHSRNSDKSSSDRS-----RRSSSSRSSSNHSRVESSKRKSAKEKKSSSKD 186
+ S R S SR +K+ D + S + +HSR SS + K+
Sbjct: 539 KGS---RESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKE 595
Query: 187 SRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATY----GTGSASRASAVSEL 242
S+ + E KE + G S+ P T+ G G A A +
Sbjct: 596 SKKEREEEFKTHHEMKEYSGFAGVSR-----------PRGTFFRIRGRGRARGVFAGTNT 644
Query: 243 SPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGY--QSGTHQG 300
P + ++ P+ P S + G Y + G +G
Sbjct: 645 GPNNSNTTF----------QKRPKEEEWDPEYTPKSKKYFLHDDRDDGVDYWAKRGRGRG 694
Query: 301 QFDHGSGSLSPSKKSPVGKSPPSTGSTY---GSSQKEESAASGGAAYTKRYLEEQK 353
F G G + K G SP T Y G + EE R EE++
Sbjct: 695 TFQRGRGRFNFKKS---GSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 747
>gi|115511057 hypothetical protein LOC256643 [Homo sapiens]
Length = 682
Score = 105 bits (261), Expect = 3e-22
Identities = 81/266 (30%), Positives = 138/266 (51%), Gaps = 23/266 (8%)
Query: 539 RKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMD-SFDEDLARPSGLLAQERKLCRDL 597
++++ S ++L P K S R+ + V++D D R + + ER++ DL
Sbjct: 381 KESNSSSNQLDKSQKLPDVKPSPINLRKKSLTVKVDVKKTVDTFRVASSYSTERQMSHDL 440
Query: 598 VHSNKKEQEFRSIFQHIQSAQS-QRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFT- 655
V +K + F +F+H+ S Q+ + P+ FAQ I+TI+H VK ++F S G+TLHERF+
Sbjct: 441 VAVGRKSENFHPVFEHLDSTQNTENKPTGEFAQEIITIIHQVKANYFPSPGITLHERFST 500
Query: 656 -KYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKD-- 712
+ + + E N PEIHRRID+S + E++S + Y++E
Sbjct: 501 MQDIHKADVNEIPLN-SDPEIHRRIDMSLA----------ELQSKQAVIYESEQTLIKII 549
Query: 713 DPVDLRLDIERRKK----HKERDLKRGKSRESVDSRDSSHSRERSAEKTE-KTHKGSKKQ 767
DP DLR DIERR+K +++ + S D ++SS S+ + ++ + THK + +
Sbjct: 550 DPNDLRHDIERRRKERLQNEDEHIFHIASAAERDDQNSSFSKNYTTQRKDIITHKPFEVE 609
Query: 768 KKHRRARDRS-RSSSSSSQSSHSYKA 792
HR R R +S+ + +YK+
Sbjct: 610 GNHRNTRVRPFKSNFRGGRCQPNYKS 635
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 103 bits (256), Expect = 1e-21
Identities = 121/432 (28%), Positives = 168/432 (38%), Gaps = 32/432 (7%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRE 61
S + +S SR+ R SRSR+ + +SRSR+ + RSR R + R RSRS +PA R
Sbjct: 566 SPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRS 625
Query: 62 RNHPRVYQNRDFRG----HNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQA 117
R V + R R R RGR+R P + R + ++ R
Sbjct: 626 RTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRS-RSR 684
Query: 118 YSPRRGRSRSRSPKR-----RSPSPRSRSHSRNSDK--SSSDRSRRSSSSRSSSNHSRVE 170
RRGRSRSR+P+R RS R RSHSR + S S R + SR+S SR
Sbjct: 685 TPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSN 744
Query: 171 SSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGT 230
SS E K S SR S++ + + S + + P +
Sbjct: 745 SS-----PEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRS 799
Query: 231 GSASRASAVSELSP-RERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPS 289
GS S+ A S P R RS + P Q R S P P + + GS
Sbjct: 800 GS-SQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSP 858
Query: 290 GAGYQSGTHQGQF------DHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAA 343
A QS T Q + D S +PS+ S G SPP S+ Q ++S
Sbjct: 859 QANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPK 918
Query: 344 YTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKM-----KSDSFAP--K 396
Q++ +G T + + S S + ++ S S +P K
Sbjct: 919 VKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTK 978
Query: 397 TDSEKPFRGSQS 408
E P R S S
Sbjct: 979 VKPETPPRQSHS 990
Score = 71.6 bits (174), Expect = 3e-12
Identities = 92/318 (28%), Positives = 133/318 (41%), Gaps = 40/318 (12%)
Query: 6 KSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHP 65
KS++ R SRS +++SR+ + RS S +RK RLS RSRS S SP R R P
Sbjct: 1664 KSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSP-ETRSRTPP 1722
Query: 66 R---------------VYQNRDFRGHNRGYRRPYYFRGRNRGFYPWG-QYNRGGYGNYRS 109
R +R R + + RGR+ P G Q +R ++
Sbjct: 1723 RHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKT 1782
Query: 110 NWQNYR------QAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSS 163
R Q+ S RR RSRSRS R S HSR+ + S R +SSR
Sbjct: 1783 RTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSR----TSSRRR 1838
Query: 164 SNHSRVESSKRKSAKEKKSSS--KDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSK 221
SR + RK ++ + S + K SR + ++ ++ S S+ + S +
Sbjct: 1839 RGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRR 1898
Query: 222 PWPDATYGT--GSASRASAVSELSPRERSPAL---KSPLQSVVVRRRS-PRPSPVPK--- 272
T T S SRAS VS R R+P + +S ++ RRRS R PV +
Sbjct: 1899 RSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRS 1958
Query: 273 --PSPPLSSTSQMGSTLP 288
+PP++ T P
Sbjct: 1959 RSRTPPVTRRRSRSRTSP 1976
Score = 68.9 bits (167), Expect = 2e-11
Identities = 95/319 (29%), Positives = 130/319 (40%), Gaps = 35/319 (10%)
Query: 2 SKTNKSKSGSRSSRSR----SASRSRSRSFSKSRSRSRSLSRSRKRRLSSRS------RS 51
S++ S + R SRSR S RSRSR+ SR RSRS + +RR SR+ RS
Sbjct: 1864 SRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRS 1923
Query: 52 RSYSPAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNW 111
RS +P R R+ R R R P R R+R P R
Sbjct: 1924 RSRTPPVTRRRSRSRTPTTR----RRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITR 1979
Query: 112 QNYRQAYSP---RRGRSRS------RSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRS 162
+ R SP RR RSR+ RS R SP R RS SR + RR S SR+
Sbjct: 1980 RRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSR-----TPPAIRRRSRSRT 2034
Query: 163 SSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGD-NQGDEAKEQTFSGGTSQDTKASESSK 221
+ S+ A ++S S+ R ++ + A + + G+S D S +
Sbjct: 2035 PLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSAT-- 2092
Query: 222 PWPDATYGTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSP-RPSPVPKPSPPLSST 280
P AT S SR V+ S R + S + + R RSP P+ P+S
Sbjct: 2093 --PPAT-RNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVL 2149
Query: 281 SQMGSTLPSGAGYQSGTHQ 299
Q G ++ G G + HQ
Sbjct: 2150 QQAGGSMMDGPGPRIPDHQ 2168
Score = 67.8 bits (164), Expect = 5e-11
Identities = 99/359 (27%), Positives = 136/359 (37%), Gaps = 39/359 (10%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRS------FSKSRSRSRSLSRSRKRRLSSRSRSRSYS 55
+KT + S S + R RSRSRS ++ R RS S + +RR SRSRSR
Sbjct: 1753 TKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRV-- 1810
Query: 56 PAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYR 115
R R Y +R RGR+R P R + W+ R
Sbjct: 1811 ---TRRRRGGSGYHSRSPARQESSRTSSRRRRGRSR--TPPTSRKRSRSRTSPAPWKRSR 1865
Query: 116 QAYSP---RRGRSRS------RSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNH 166
SP RR RSR+ RS R SP R RS SR S RSR S SR S
Sbjct: 1866 SRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRS 1925
Query: 167 -----SRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSK 221
+R S R ++S S+ ++ ++ + TS T+ S+
Sbjct: 1926 RTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSR 1985
Query: 222 PWPDATYGTGSASRASAVSELSPRER-SPALKSPLQS---VVVRRRSPRPSPV-----PK 272
P S SR S V+ R R SP + +S +RRRS +P+ +
Sbjct: 1986 TSP--VTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSR 2043
Query: 273 PSPPLSSTSQMGSTLPSGA-GYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGS 330
PL+ + S P A G +S T + S +PP+T + GS
Sbjct: 2044 SRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGS 2102
Score = 67.4 bits (163), Expect = 6e-11
Identities = 117/551 (21%), Positives = 192/551 (34%), Gaps = 69/551 (12%)
Query: 4 TNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERN 63
+++ S S +S++RS R++ R S S + SR + RSR + R RSRS +P
Sbjct: 449 SHREISSSPTSKNRSHGRAK-RDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTK----- 502
Query: 64 HPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRG 123
RGH+R R P + R R+ WG R
Sbjct: 503 ----------RGHSRS-RSPQWRRSRSA--QRWG------------------------RS 525
Query: 124 RSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSS 183
RS R + RSP S SRN+ + RS R S S S +R S R A+ +S
Sbjct: 526 RSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSR 585
Query: 184 SKD---SRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVS 240
S+ R + ++ G + T A S+ + S SR+ A
Sbjct: 586 SRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSR--TRSPVRRRSRSRSPARR 643
Query: 241 ELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQG 300
R R+PA + +S R+P + P + + S P+ G
Sbjct: 644 SGRSRSRTPARRGRSRS-----RTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPR 698
Query: 301 QFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDK 360
+ S SL +S ++P G + SS+++ + + E K +
Sbjct: 699 RGRSRSRSLVRRGRSH-SRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSR 757
Query: 361 EQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEK 420
+ ++ + K K + S + + S PK S+ P R S+S
Sbjct: 758 RSRSLSSPRSKAKSRLSLRRS------LSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTP 811
Query: 421 KMADFHKEEMDDQDKDKAKGRK-ESEFDDEPKFMSKV------IGANKNQEEEKSGKWEG 473
+ K K R+ S PK S I + + E+ + +
Sbjct: 812 PRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRS 871
Query: 474 LVYAPPGKEKQRKTEELE--EESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQE 531
+ P E + +T S P R K ++S P+ ++ +
Sbjct: 872 CFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHS 931
Query: 532 KSSSPPPRKTS 542
SSSP P + +
Sbjct: 932 GSSSPSPSRVT 942
Score = 66.2 bits (160), Expect = 1e-10
Identities = 86/328 (26%), Positives = 138/328 (42%), Gaps = 28/328 (8%)
Query: 3 KTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRS-----RSRSYSPA 57
+ ++S S +SR R SRSRSR + R S SRS R+ SSR+ R RS +P
Sbjct: 1787 RRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPP 1846
Query: 58 HNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQA 117
+R+R+ R R +R + R R+R + +R R +
Sbjct: 1847 TSRKRSRSRTSPAPWKRSRSRASPATHR-RSRSRTPLISRRRSRSRTSPVSRRRSRSRTS 1905
Query: 118 YSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSA 177
+ RR RSR+ RR R+ +R +S + +RR S SR+ R S+
Sbjct: 1906 VTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPV 1965
Query: 178 KEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSAS--- 234
++S S+ S ++ ++ + TS T+ S+ P + S +
Sbjct: 1966 TRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPA 2025
Query: 235 ---RASAVSELSPRERSPALKSPLQSVVVRRRSPRPSP--------VPKPSPPLSSTSQM 283
R+ + + L PR+RS + +SPL +RRRS +P + + P + S
Sbjct: 2026 IRRRSRSRTPLLPRKRSRS-RSPL---AIRRRSRSRTPRTARGKRSLTRSPPAIRRRSAS 2081
Query: 284 GSTLPSGAGYQSGTHQGQFDHGSGSLSP 311
GS S +S T +H SGS +P
Sbjct: 2082 GS---SSDRSRSATPPATRNH-SGSRTP 2105
Score = 64.7 bits (156), Expect = 4e-10
Identities = 97/485 (20%), Positives = 175/485 (36%), Gaps = 58/485 (11%)
Query: 100 NRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKR--RSPSPRSRSHSRNSDKS-------- 149
+RG S + +++ ++ RS S S KR RSP+P+S+ S++ +
Sbjct: 195 DRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPA 254
Query: 150 -SSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSR-PSQAAG-DNQGDEAKEQTF 206
S R+ RS+S+ S+S+ S R +A + +++ R PS A+G +GD +
Sbjct: 255 PKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPG 314
Query: 207 SGGT----SQDTKASESSKPWPDATYG--TGSASRASAVSELSPRERSPALKSPLQSVVV 260
+ T S +T + S P+ D SA+R S E S P +PL +
Sbjct: 315 TTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPL---LA 371
Query: 261 RRRSPRPSPV---PKPSPPLSSTSQMGST-----------LPSGAGYQSGTHQGQFDHGS 306
R P P+ P P++ S+ T LP + +S Q S
Sbjct: 372 ERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVS 431
Query: 307 GSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTN 366
S S +SP P + SS ++ + G A K + G+ +
Sbjct: 432 RHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAK 491
Query: 367 TDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFH 426
+ + S + T G + +S + +++ R +R + R +
Sbjct: 492 RGRSR-----SRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSR 546
Query: 427 KEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRK 486
+ + + +GR S G ++++ + G+ P + + R
Sbjct: 547 NTQRRGRSRSARRGRSHSR-------SPATRGRSRSRTPARRGRSRS---RTPARRRSRS 596
Query: 487 TEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRD 546
P R + R G R P + T + S P R++ SR
Sbjct: 597 RT-------PTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRS 649
Query: 547 KLGAK 551
+ A+
Sbjct: 650 RTPAR 654
Score = 60.1 bits (144), Expect = 1e-08
Identities = 145/723 (20%), Positives = 228/723 (31%), Gaps = 79/723 (10%)
Query: 115 RQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKR 174
R+A P + S R S S RS + + K DR RRS S SS R +SSK+
Sbjct: 158 REAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSES--SSPRRERKKSSKK 215
Query: 175 KSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSAS 234
K + + S K S + + K++ K S S+ P P + S S
Sbjct: 216 KKHRSESESKKRKHRSPTPKSKRKSKDKKR----------KRSRSTTPAPKSRRAHRSTS 265
Query: 235 RASAVSELSPRERSPALKSPLQSVVVRRRSPRPS-------PVPKPSPPLSSTSQMGSTL 287
SA S + R RS + + + + RSP P+ P P +ST + S
Sbjct: 266 ADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSS-- 323
Query: 288 PSGAGYQSGTHQGQFDHGSGSLSPSKKSP------VGKSPPSTGSTYGSSQKEESAASGG 341
P A Q + D S ++ SP G PP+ E S
Sbjct: 324 PETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLA----ERHGGSPQ 379
Query: 342 AAYTKRYLEEQKTENGKDKEQKQTNTDK--EKIKEKGSFSDTGLGDGKMKSD---SFAPK 396
T +E + + + K EK+ + S + K S +P+
Sbjct: 380 PLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPE 439
Query: 397 TDSEKPFRGS----QSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKF 452
+ P GS S K R K +++ + GR S +
Sbjct: 440 SPKPAPAPGSHREISSSPTSKNRSHGRAK-----RDKSHSHTPSRRMGRSRSPATAKRGR 494
Query: 453 MSKVIGANKNQEEEKSGKWE--------GLVYAP-----------PGKEKQRKTEELEEE 493
+ +S +W G +P PG + R T+
Sbjct: 495 SRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRS 554
Query: 494 SFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGD 553
R + R + G R P + R + + +S S P + SR + A+
Sbjct: 555 RSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTR-RRSRSRTPARRG 613
Query: 554 FPTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQH 613
++ + VR S AR SG R S + RS
Sbjct: 614 RSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRS-RSR 672
Query: 614 IQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMT----LHERFTKYLKRGTEQEAAKN 669
+ +S RS S A+ + + S + H R + R KN
Sbjct: 673 TPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKN 732
Query: 670 KKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKE 729
K R S +K ++ +S P KA+ RL + R
Sbjct: 733 KSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKS---------RLSLRRSLSGSS 783
Query: 730 RDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHS 789
K+ SR S + + + + S ++++ SR S SSS
Sbjct: 784 PCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPK 843
Query: 790 YKA 792
K+
Sbjct: 844 VKS 846
Score = 58.2 bits (139), Expect = 4e-08
Identities = 153/735 (20%), Positives = 251/735 (34%), Gaps = 101/735 (13%)
Query: 133 RSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQA 192
+ S RS HS S + S D ++ S + S S V + ++ ++SSS S P
Sbjct: 1372 KEQSTRSSGHS--SSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASS-PEMK 1428
Query: 193 AGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPRERSPALK 252
G + + ++ S +D + S ++ G R + S + SP K
Sbjct: 1429 DGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGR-SECDSSPEPK 1487
Query: 253 SPLQSVVVRRRSPRP--------SPVPKPSPPLSSTSQMG-STLPSGAGYQSGTHQGQFD 303
+ Q+ R RSP +P + S SS Q + P G +SG+ Q + D
Sbjct: 1488 ALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQ-ELD 1546
Query: 304 HGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQK 363
S SP ++S SP S T ++ + S +K L +++ +G E K
Sbjct: 1547 V-KPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVK 1605
Query: 364 QTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMA 423
DK + + D + + AP+ + GS S R +
Sbjct: 1606 ----DKPRAAPRAQSG----SDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE------G 1651
Query: 424 DFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEK 483
E + R+ S EPK S+ PP +
Sbjct: 1652 SSSTESSPEHPPKSRTARRGSRSSPEPKTKSR---------------------TPPRRRS 1690
Query: 484 QRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSE 543
R + EL ++ R + R S R P ++ R + SS P K+
Sbjct: 1691 SRSSPELTRKA---RLSRRSRSASSSPETRSRTPPRHRRSPSV------SSPEPAEKSRS 1741
Query: 544 SRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKK 603
SR + A P K++ R +P GL + R+ + ++
Sbjct: 1742 SRRRRSASS--PRTKTTSRRGRSPS------------PKPRGLQRSRSRSRREKTRTTRR 1787
Query: 604 EQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRG-- 661
S + Q RS S + + +H + S T R +RG
Sbjct: 1788 RDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRR-----RRGRS 1842
Query: 662 ----TEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDL 717
T ++ ++++ SP +R S R H +S + + + PV
Sbjct: 1843 RTPPTSRKRSRSRTSPAPWKR-----SRSRASPATHRRSRSRTPLISRRRSRSRTSPVSR 1897
Query: 718 RLDIERRKKHKERDLKRGK--SRESVDSRDSSHSRERSAEKTEKTHKGSKKQK---KHRR 772
R R + R R SR SR +R RS +T T + S+ + RR
Sbjct: 1898 RRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRR 1957
Query: 773 ARDRS------RSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERG 826
+R R+ RS S +S + + T R S T +R ++ P R
Sbjct: 1958 SRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTS-PVTRRRSRSRTSPVTRR 2016
Query: 827 GGRARGTFQFRARGR 841
R+R R R R
Sbjct: 2017 RSRSRTPPAIRRRSR 2031
Score = 54.7 bits (130), Expect = 4e-07
Identities = 145/723 (20%), Positives = 249/723 (34%), Gaps = 97/723 (13%)
Query: 119 SPRRGRSRSRS-PKRRS-----PSPRSRSHSRNSDKSSSDRSRRSSSSRS---------- 162
+P R RS S S P+ + PS RSRS S + S R S S S
Sbjct: 1413 TPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRT 1472
Query: 163 -SSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQ---------GDEAK---------- 202
S S +SS A + + PS +N+ G E+
Sbjct: 1473 PSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTP 1532
Query: 203 -EQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPRER---SPALKSPLQSV 258
Q G+SQ+ S+ P + + S+A + L R R SP + S +
Sbjct: 1533 LGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSK-SRL 1591
Query: 259 VVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVG 318
RR SP K P + +Q GS S + S S S G
Sbjct: 1592 SPRRSRSGSSPEVKDKPRAAPRAQSGSD-------SSPEPKAPAPRALPRRSRSGSSSKG 1644
Query: 319 KSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSF 378
+ P GS+ S E S A R E KT++ + +++++ ++ K
Sbjct: 1645 RGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKS-RTPPRRRSSRSSPELTRKARL 1703
Query: 379 SDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKA 438
S + +S S +P+T S P R +SP + +K + + K
Sbjct: 1704 S------RRSRSASSSPETRSRTPPRHRRSPS--VSSPEPAEKSRSSRRRRSASSPRTKT 1755
Query: 439 KGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPER 498
R+ +P+ + + ++ ++ + + + R +R
Sbjct: 1756 TSRRGRSPSPKPRGLQRSRSRSRREKTRTT------------RRRDRSGSSQSTSRRRQR 1803
Query: 499 SKKEDRGKRSEGGHRGF-----VPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGD 553
S+ R R G G+ +++ R ++ + + P RK S SR A
Sbjct: 1804 SRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTS-PAPWK 1862
Query: 554 FPTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQH 613
++S + R ++ + S +R S + R+ R ++ R+
Sbjct: 1863 RSRSRASPATHRRSRSRTPLISRRRSRSRTSPV---SRRRSRSRTSVTRRRSRSRASPVS 1919
Query: 614 IQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSP 673
+ ++S+ P T + S + R ++ + ++++ SP
Sbjct: 1920 RRRSRSRTPPVTRRRSRSRTPTTRRRSR---SRTPPVTRRRSRSRTPPVTRRRSRSRTSP 1976
Query: 674 EIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLD-------IERRKK 726
RR S R + +S P + + + PV R I RR +
Sbjct: 1977 ITRRR-----SRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSR 2031
Query: 727 HKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQS 786
+ L R +SR SR R RS +T +T +G + + A R +S SSS
Sbjct: 2032 SRTPLLPRKRSR----SRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDR 2087
Query: 787 SHS 789
S S
Sbjct: 2088 SRS 2090
Score = 53.1 bits (126), Expect = 1e-06
Identities = 186/869 (21%), Positives = 298/869 (34%), Gaps = 115/869 (13%)
Query: 119 SPRRGRSRSRSP----KRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRS-SSNHSRVESSK 173
SP+ GRSRS SP RSP + R S S S S +S SS++ V+S+
Sbjct: 1093 SPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNS 1152
Query: 174 ---RKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGT 230
+ + +S K + P Q K++ FS QD ESS + D T T
Sbjct: 1153 LLGQSRLETAESKEKMALPPQEDATASPPRQKDK-FSPFPVQD--RPESSLVFKD-TLRT 1208
Query: 231 GSASRASAVSELSPRERSPALKS-----PLQSVVVRRRSP-------------------- 265
R+ A S +E++ AL + L VV + P
Sbjct: 1209 PPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNF 1268
Query: 266 RPSPVPKPSPPLSST---SQMGSTL-----PSGAGYQSGTHQGQFDHGSGSLSPSKKSPV 317
SP + P +S T SQ ++L PS A G H +H S SP +++
Sbjct: 1269 ESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSP-EHKELSNSPLRENSF 1327
Query: 318 G-------KSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKE 370
G P T G S + + +G +L + +T+ D +++ T +
Sbjct: 1328 GSPLEFRNSGPLGTEMNTGFSSEVKEDLNG------PFLNQLETDPSLDMKEQSTRSSGH 1381
Query: 371 KIKE--KGSFSDTGLGDGKMKSD---SFAPKTDSEK-----------------PFRGSQS 408
E + G+ + S P+T S + P R S+S
Sbjct: 1382 SSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRS 1441
Query: 409 PKRYKLRDDF---EKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEE 465
LRD + M D + ++GR E + EPK + +
Sbjct: 1442 GSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQT--PRPRSRS 1499
Query: 466 EKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTA 525
S + P QR+ E + + G+RS G E + + +A
Sbjct: 1500 PSSPELNNKCLTP-----QRERSGSESSVDQKTVARTPLGQRSRSGSS---QELDVKPSA 1551
Query: 526 YKAVQEKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSG 585
+ +S S P K +++R L + + S +R + R S E +P
Sbjct: 1552 SPQERSESDSSPDSK-AKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPR- 1609
Query: 586 LLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQ--RSPSELFAQHIVTIVHHVKEHHF 643
A R K R++ + +S S R PS + + H +
Sbjct: 1610 --AAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRT 1667
Query: 644 GSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPG 703
G K T ++ SPE+ R+ +S + + + E +S P
Sbjct: 1668 ARRGSRSSPE--PKTKSRTPPRRRSSRSSPELTRKARLSRRS--RSASSSPETRSRTPPR 1723
Query: 704 YKAEGKYKD-DPVDLRLDIERRKK----HKERDLKRGKSRESVDSRDSSHSRERS-AEKT 757
++ +P + RR+ + +RG+S S R SR RS EKT
Sbjct: 1724 HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRS-PSPKPRGLQRSRSRSRREKT 1782
Query: 758 EKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTK 817
T + + +R R RS S S + Y + R+ES+ + R G +
Sbjct: 1783 RTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRG-R 1841
Query: 818 DFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNR-EEEWDPEYTPK 876
P+ R R+R + R R R + + + + S R R P +
Sbjct: 1842 SRTPPTSRKRSRSRTSPAPWKRSR--SRASPATHRRSRSRTPLISRRRSRSRTSPVSRRR 1899
Query: 877 SKKYYLHDDREGEGSDKWVSRGRGRGAFP 905
S+ R VSR R R P
Sbjct: 1900 SRSRTSVTRRRSRSRASPVSRRRSRSRTP 1928
Score = 52.4 bits (124), Expect = 2e-06
Identities = 52/206 (25%), Positives = 77/206 (37%), Gaps = 37/206 (17%)
Query: 131 KRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPS 190
K R S S S S +S SSS S SSS SSS+ + K+ S P
Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPK 2587
Query: 191 QAAGDNQGDE---AKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPRER 247
+A + + E AK + S +S + +S SS ++ + S+S +S+ S S
Sbjct: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647
Query: 248 SPALKSPLQSVVVRRRSP----------------------------------RPSPVPKP 273
SP+ P + + SP RPSP P P
Sbjct: 2648 SPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSP 2707
Query: 274 SPPLSSTSQMGSTLPSGAGYQSGTHQ 299
SS+S+ GS +S +H+
Sbjct: 2708 RDQQSSSSERGSRRGQRGDSRSPSHK 2733
Score = 49.3 bits (116), Expect = 2e-05
Identities = 80/345 (23%), Positives = 133/345 (38%), Gaps = 56/345 (16%)
Query: 1 MSKTNKSKSGSRSS---RSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPA 57
+ +T + +S S SS ++ + R RS S+S ++++R+ L RSRS S
Sbjct: 1489 LPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTP---LGQRSRSGSSQEL 1545
Query: 58 HNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQA 117
+ P+ D ++ R P Q +R G S + +
Sbjct: 1546 DVKPSASPQERSESDSSPDSKAKTRT-----------PLRQRSRSG----SSPEVDSKSR 1590
Query: 118 YSPRRGRSRSR-------------------SPKRRSPSPRS---RSHSRNSDKSSSDRSR 155
SPRR RS S SP+ ++P+PR+ RS S +S K
Sbjct: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE 1650
Query: 156 RSSSSRSSSNH-SRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDT 214
SSS+ SS H + +++R S + +K P + E + ++ +
Sbjct: 1651 GSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRK------ARLS 1704
Query: 215 KASESSKPWPDATYGTGSASRAS-AVSELSPRERSPALK-----SPLQSVVVRRRSPRPS 268
+ S S+ P+ T R S +VS P E+S + + S ++ RR PS
Sbjct: 1705 RRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPS 1764
Query: 269 PVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSK 313
P P+ S S+ T + +SG+ Q S S S+
Sbjct: 1765 PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSR 1809
Score = 47.8 bits (112), Expect = 5e-05
Identities = 132/662 (19%), Positives = 209/662 (31%), Gaps = 108/662 (16%)
Query: 261 RRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKS 320
RR P P+P P S + S S S +P +K K
Sbjct: 155 RRAREAKQPAPEPPKPYSLVRESSS--------------------SRSPTPKQKKKKKKK 194
Query: 321 PPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSD 380
S S ++E +S K+ ++E+ K K + T K K K+K
Sbjct: 195 DRGRRSESSSPRRERKKSS------KKKKHRSESESKKRKHRSPTPKSKRKSKDKK---- 244
Query: 381 TGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKL---RDDFEKKMADFHKEEMDDQDKDK 437
+ +S S P S + R + + R A H + +
Sbjct: 245 ------RKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSP 298
Query: 438 AKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPE 497
A GR+ D P + E + K Y K+K+ K+ S PE
Sbjct: 299 ASGRRGE--GDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPS-PE 355
Query: 498 RSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSP--PPRKTSESRDKLGAKGDFP 555
RS + E++ A S P PP + S +RD+ K
Sbjct: 356 RSSTGPEPPAPTP----LLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEK 411
Query: 556 TGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQ 615
+SS S + + PS Q K+ R S + + + H +
Sbjct: 412 LPQSSSS----------------ESSPPS---PQPTKVSRHASSSPESPKPAPAPGSHRE 452
Query: 616 SAQSQRSPSELFAQHIVTIVH-HVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPE 674
+ S S + + H H G S + + R + +SP+
Sbjct: 453 ISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQ 512
Query: 675 IHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKR 734
R + +SP+ PG+ + R + H R
Sbjct: 513 WRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRR--GRSRSARRGRSHSRSPATR 570
Query: 735 GKSRESVD-----SRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRS---------- 779
G+SR SR + +R RS +T T + S+ + RR R RSR+
Sbjct: 571 GRSRSRTPARRGRSRSRTPARRRSRSRTP-TRRRSRSRTPARRGRSRSRTPARRRSRTRS 629
Query: 780 -----SSSSSQSSHSYKAEEYTEETEEREESTT----GFDKSRL-----GTKDFVGPSER 825
S S S + S ++ T R S T G +SR G P+ R
Sbjct: 630 PVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARR 689
Query: 826 GGGRARGTFQFRARGRGWGRGNYS--------GNNNNNSNNDFQKRNREEEWDPEYTPKS 877
G R+R + R+R R R S G + ++S + R + +P+
Sbjct: 690 GRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEM 749
Query: 878 KK 879
KK
Sbjct: 750 KK 751
Score = 46.2 bits (108), Expect = 1e-04
Identities = 55/243 (22%), Positives = 85/243 (34%), Gaps = 21/243 (8%)
Query: 171 SSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGT 230
+ +R+S+ SSS S S ++ + + S G+S + + K P T
Sbjct: 2527 AKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT--- 2583
Query: 231 GSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSG 290
+ AV E P E +PA +R R S S SS+S S+ S
Sbjct: 2584 --PAPKEAVREGRPPEPTPA-----------KRKRRSSSSSSSSSSSSSSSSSSSSSSSS 2630
Query: 291 AGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGS--TYGSSQKEESAASGGAAYTKRY 348
+ S + S S SP+K P P++ G + + R
Sbjct: 2631 SSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRS 2690
Query: 349 LEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPF--RGS 406
L E + Q + E+GS GD + S +T S +P R S
Sbjct: 2691 LSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQ-RGDSRSPSHKRRRETPSPRPMRHRSS 2749
Query: 407 QSP 409
+SP
Sbjct: 2750 RSP 2752
Score = 41.2 bits (95), Expect = 0.005
Identities = 56/183 (30%), Positives = 71/183 (38%), Gaps = 39/183 (21%)
Query: 6 KSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHP 65
K +S S SS S S+S S S S S S S S S S S SS S S S SPA + P
Sbjct: 2604 KRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---SSSSSSSSPSPAKPGPQALP 2660
Query: 66 RVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRS 125
+ + R R P + S R RS
Sbjct: 2661 KPASPKKPPPGERRSRSPR------------------------------KPIDSLRDSRS 2690
Query: 126 RSRSP-KRRSPSPRSRSHSRNSDKSSSDRSRR---SSSSRSSSNHSRVESSKRKSAKEKK 181
S SP +RR PSP + R+ SSS+R R SRS S+ R E+ + + +
Sbjct: 2691 LSYSPVERRRPSP--QPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRS 2748
Query: 182 SSS 184
S S
Sbjct: 2749 SRS 2751
Score = 38.1 bits (87), Expect = 0.040
Identities = 29/113 (25%), Positives = 44/113 (38%), Gaps = 18/113 (15%)
Query: 718 RLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRS 777
R R + +RG+SR +R S SR R+ + +G + + RR R RS
Sbjct: 650 RTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPAR-----RGRSRSRTPRRGRSRS 704
Query: 778 RS-------------SSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTK 817
RS S SS K + T + R S+ KSR+ ++
Sbjct: 705 RSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSR 757
Score = 37.0 bits (84), Expect = 0.088
Identities = 76/333 (22%), Positives = 114/333 (34%), Gaps = 75/333 (22%)
Query: 3 KTNKSKSGSRSSRSRSAS-RSRSRSFSKSRSRSRSLSRSRKRRLSSRS------------ 49
K ++S+S S+ + RS + +S+ +S K R RSRS + + K R + RS
Sbjct: 216 KKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTS 275
Query: 50 RSRSYSPAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRG-RNRGFYPWGQYNRGGYGNYR 108
RSRS S A + H R P G R G P+ +
Sbjct: 276 RSRSRSAA---AKTHTTALAGRS----------PSPASGRRGEGDAPFSE---------- 312
Query: 109 SNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSR 168
R SP+ + P S ++ DK +R S S SS
Sbjct: 313 ----------PGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPE 362
Query: 169 VESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATY 228
+ A+ S P A E ++D +S + P
Sbjct: 363 PPAPTPLLAERHGGS-----PQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQ--- 414
Query: 229 GTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLP 288
S+ SE SP SP + V R S P PKP+P S ++ S+ P
Sbjct: 415 --------SSSSESSP-------PSPQPTKVSRHASSSPES-PKPAPAPGSHREISSS-P 457
Query: 289 SGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSP 321
+ G + H S +PS++ +SP
Sbjct: 458 TSKNRSHGRAKRDKSH---SHTPSRRMGRSRSP 487
Score = 35.0 bits (79), Expect = 0.33
Identities = 42/156 (26%), Positives = 54/156 (34%), Gaps = 14/156 (8%)
Query: 115 RQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKR 174
R+ S S S S S S S S S +S SSS S SSSS S + K
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662
Query: 175 KSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSAS 234
S K+ + SR + D+ D S S P P S+S
Sbjct: 2663 ASPKKPPPGERRSRSPRKPIDSLRD-------SRSLSYSPVERRRPSPQPSPRDQQSSSS 2715
Query: 235 RASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPV 270
+ RSP+ K RR +P P P+
Sbjct: 2716 ERGSRRGQRGDSRSPSHKR-------RRETPSPRPM 2744
Score = 33.1 bits (74), Expect = 1.3
Identities = 39/138 (28%), Positives = 61/138 (44%), Gaps = 13/138 (9%)
Query: 683 PSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVD-LRLDIERRKKHKERDLKRGKSRESV 741
P+ H LA E+ + +A D VD D +RR + ++ S+
Sbjct: 116 PAVTETHQLA--ELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSL 173
Query: 742 DSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETE- 800
R+SS SR T K KK+KK R R RS SSS + S K +++ E+E
Sbjct: 174 -VRESSSSRS-------PTPKQKKKKKKKDRGR-RSESSSPRRERKKSSKKKKHRSESES 224
Query: 801 EREESTTGFDKSRLGTKD 818
++ + + KS+ +KD
Sbjct: 225 KKRKHRSPTPKSKRKSKD 242
Score = 30.8 bits (68), Expect = 6.3
Identities = 23/94 (24%), Positives = 41/94 (43%), Gaps = 14/94 (14%)
Query: 733 KRGKSRESVDSRDSSHSR---------ERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSS 783
+RG+SR R S SR R+ ++ ++ S+++ K R ++ RSRS+SS
Sbjct: 688 RRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSP 747
Query: 784 SQSSHSYKAEEYTEETEEREESTTGFDKSRLGTK 817
+ + R ++ KSRL +
Sbjct: 748 EMKKSRISSRRSRSLSSPRSKA-----KSRLSLR 776
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 99.4 bits (246), Expect = 1e-20
Identities = 94/291 (32%), Positives = 140/291 (48%), Gaps = 40/291 (13%)
Query: 2 SKTNKSKSGSRSS---RSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSS----RSRSRSY 54
S+ ++S+SGS S +SRS SRS SRS SKSRSRS+S SRS+K + S +SRSRS+
Sbjct: 201 SRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSH 260
Query: 55 SPAHNRERNHPRV---YQNRDFRGHNRGYRRPYYFRGRNRG-----FYPWGQYNRGGYGN 106
S +R ++ + QN D G + R P + +++ + RG
Sbjct: 261 SAGKSRSKSKDQAEEKIQNNDNVGKPKS-RSPSRHKSKSKSRSRSQERRVEEEKRGSVSR 319
Query: 107 YRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRS-HSRNSDKSSSDRSRRSSSSRSSSN 165
RS ++ RQ+ R RSRS+ R RS+S R K S + SR S SRS S
Sbjct: 320 GRSQEKSLRQS----RSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSE 375
Query: 166 HSRVESSKR--KSAKEKKSSSKDSRPSQ--------------AAGDNQGDEAKEQTFSGG 209
SR SKR K+ KK +D+ SQ A ++ E + ++ + G
Sbjct: 376 RSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAG 435
Query: 210 TSQDTKASESSKPWPDATYGTGSASRASAVSELSPRERS---PALKSPLQS 257
T+Q+T++ S + S SR+ + S+ R +S A +SP +S
Sbjct: 436 TNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRS 486
Score = 89.7 bits (221), Expect = 1e-17
Identities = 97/328 (29%), Positives = 144/328 (43%), Gaps = 36/328 (10%)
Query: 6 KSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHP 65
+ K GSR RS S SRS SRS S+SR +S SRS + SS S+SRS S + +R R+
Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSK-SSHSKSRSRSRSGSRSRSKS 232
Query: 66 RVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRS 125
R R R P + R+R ++ G + + + + G+
Sbjct: 233 RSRSQSRSRSKKEKSRSPSKEKSRSR------SHSAGKSRSKSKDQAEEKIQNNDNVGKP 286
Query: 126 RSRSPKRRSPSPRSRSHSRN-----------SDKSSSDRSRRSSSSRS-SSNHSRVESSK 173
+SRSP R +SRS S+ S S ++S R S SRS S SR S
Sbjct: 287 KSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRS 346
Query: 174 RKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSA 233
R +K+K+ K SR ++ ++ E++ G+ +D+KA S K + T + S
Sbjct: 347 RSKSKDKRKGRKRSR-EESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSR 405
Query: 234 S--------RASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGS 285
S R A SE S RE ++ + R RS R + KP+ P S S+ S
Sbjct: 406 SPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRS-RSNSKSKPNLPSESRSRSKS 464
Query: 286 TLPSGAGYQSGTHQGQFDHGSGSLSPSK 313
+ + +S + S S SPS+
Sbjct: 465 ASKTRSRSKSRSR-------SASRSPSR 485
Score = 67.4 bits (163), Expect = 6e-11
Identities = 85/321 (26%), Positives = 122/321 (38%), Gaps = 33/321 (10%)
Query: 115 RQAYSPRRGRSRSRSPKRRSPSPRSRS-HSRNSDKSSSDRSRRSSSSRSSSNHSRVESSK 173
R++YS R SRSRS R S RSRS S++S S RSR S SRS S S+
Sbjct: 182 RRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSR 241
Query: 174 RKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSA 233
K K + S + SR + ++K+Q + D S+ S
Sbjct: 242 SKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR----------SP 291
Query: 234 SRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGY 293
SR + S+ R + ++ + V R RS S S S S+ GS S +
Sbjct: 292 SRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRS---RSRSKGGSRSRSRSRS 348
Query: 294 QS-----GTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQK------EESAASGGA 342
+S G + + + S S S SK K S GSS+K + S + +
Sbjct: 349 KSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPS 408
Query: 343 AYTKRYLEEQKTENGK-----DKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKT 397
+ E K+E+ + + E TN + S S L A KT
Sbjct: 409 RSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKT 468
Query: 398 DSEKPFR---GSQSPKRYKLR 415
S R S+SP R + R
Sbjct: 469 RSRSKSRSRSASRSPSRSRSR 489
Score = 65.9 bits (159), Expect = 2e-10
Identities = 58/187 (31%), Positives = 80/187 (42%), Gaps = 32/187 (17%)
Query: 1 MSKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKR-RLSSRSRSRSYSPAHN 59
+S+ + R SRSRS S+ SRS S+SRS+S+ + RKR R SRSRSRS S +
Sbjct: 317 VSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSE- 375
Query: 60 RERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYS 119
R RG +R G + + Q+ S
Sbjct: 376 --------------RSRKRGSKR---------------DSKAGSSKKKKKEDTDRSQSRS 406
Query: 120 PRRGRSRSRSPKRRSPSPR-SRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAK 178
P R S+ R + S R R S N+ + RSR S+S+S N S+ KSA
Sbjct: 407 PSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSAS 466
Query: 179 EKKSSSK 185
+ +S SK
Sbjct: 467 KTRSRSK 473
Score = 63.2 bits (152), Expect = 1e-09
Identities = 59/201 (29%), Positives = 92/201 (45%), Gaps = 18/201 (8%)
Query: 5 NKSKSGSRS-SRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLS---SRSRSRSYSPAHNR 60
+KSKS SRS S+ R + S S+ RS+ +SL +SR R S SRSRSRS S + ++
Sbjct: 294 HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDK 353
Query: 61 ERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSP 120
+ R + R +R RG R + RS ++ ++ S
Sbjct: 354 RKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSK 413
Query: 121 RRGRSRSRSPKRRS--------PSPRSRSHSRNSDKS-----SSDRSRRSSSSRS-SSNH 166
R ++S S +R + +RS SR++ KS S RSR S+S++ S +
Sbjct: 414 EREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSK 473
Query: 167 SRVESSKRKSAKEKKSSSKDS 187
SR S+ R ++ + S S
Sbjct: 474 SRSRSASRSPSRSRSRSHSRS 494
Score = 55.1 bits (131), Expect = 3e-07
Identities = 44/177 (24%), Positives = 81/177 (45%), Gaps = 11/177 (6%)
Query: 697 KSPREPGYKAEGKYKDDPVDLRLDIERRK-----KHKERDLKRGKSRESVDSRDSSHSRE 751
KS +K++ K + + R++ E+R + +E+ L++ +SR S+ S SR
Sbjct: 287 KSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSR--SKGGSRSRS 344
Query: 752 RSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDK 811
RS K++ KG K+ ++ R+R RSRS S S+ S + + ++++E T D+
Sbjct: 345 RSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDT---DR 401
Query: 812 SRLGTKDFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEE 868
S+ + ER ++ + Q RG G + + +N K N E
Sbjct: 402 SQSRSPSRSVSKEREHAKSESS-QREGRGESENAGTNQETRSRSRSNSKSKPNLPSE 457
Score = 52.4 bits (124), Expect = 2e-06
Identities = 99/469 (21%), Positives = 157/469 (33%), Gaps = 69/469 (14%)
Query: 356 NGKDKEQKQTNTDKEK-IKEKGSFSDTGLGDGKMKS--DSFAPKTDSEKPFRGSQSPKRY 412
NGKD ++ + + + GS+ G G +S D + P T +E R
Sbjct: 56 NGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRC 115
Query: 413 KLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWE 472
+D + D+ ++ + D KGRK + + K E +G+
Sbjct: 116 SWQD-----LKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKI 170
Query: 473 GLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEK 532
LV PG ++R S + R RS G
Sbjct: 171 RLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSG--------------------- 209
Query: 533 SSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERK 592
SS S SR + G++ + S S +R + R S ++ +R S + R
Sbjct: 210 -SSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSR-SHSAGKSRS 267
Query: 593 LCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHE 652
+D + +K Q ++ RSPS H K S E
Sbjct: 268 KSKD--QAEEKIQNNDNV-----GKPKSRSPSR----------HKSKSKSRSRS----QE 306
Query: 653 RFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKD 712
R + KRG+ +KS R S R + + K R+ ++ + +
Sbjct: 307 RRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRS 366
Query: 713 DPVDLRLDIERRKKHKERDLKRG----KSRESVDSRDSSHSRERSAEKTEKTHKGSKKQK 768
RK+ +RD K G K +E D R S S RS K + K Q+
Sbjct: 367 RSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTD-RSQSRSPSRSVSKEREHAKSESSQR 425
Query: 769 KHR------------RARDRSRSSSSSSQSSHSYKAEEYTEETEEREES 805
+ R R+R RS S S + S S + +T R +S
Sbjct: 426 EGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKS 474
Score = 48.9 bits (115), Expect = 2e-05
Identities = 51/238 (21%), Positives = 92/238 (38%), Gaps = 14/238 (5%)
Query: 717 LRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDR 776
+RL ++ + R R +S SR + RS + K+ + + +R R
Sbjct: 170 IRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSR 229
Query: 777 SRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQF 836
S+S S S S S K + + E+ + KSR +KD +
Sbjct: 230 SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNV------ 283
Query: 837 RARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYT-PKSKKYYLHDDR---EGEGSD 892
G+ R + + S + Q+R EEE + +S++ L R +G
Sbjct: 284 ---GKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGS 340
Query: 893 KWVSRGRGRGAFPR-GRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREEKDN 949
+ SR R + R GR R S S + + S + G D ++G+ +++K++
Sbjct: 341 RSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKED 398
Score = 46.2 bits (108), Expect = 1e-04
Identities = 64/283 (22%), Positives = 100/283 (35%), Gaps = 45/283 (15%)
Query: 636 HHVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHR---RIDISPSTFRKHGLA 692
H K S + H + + G+ + +S R SPS + +
Sbjct: 200 HSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRS 259
Query: 693 HDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRER 752
H KS + +AE K +++ + K K R R KS+ SR S R
Sbjct: 260 HSAGKSRSKSKDQAEEKIQNN--------DNVGKPKSRSPSRHKSKSK--SRSRSQERRV 309
Query: 753 SAEKTEKTHKGSKKQKKHR--RARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFD 810
EK +G ++K R R+R RS+ S S S S ++ REES
Sbjct: 310 EEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREES----- 364
Query: 811 KSRLGTKDFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWD 870
R R+R + R+R RG R + +G++ D +R +
Sbjct: 365 --------------RSRSRSRSKSE-RSRKRGSKRDSKAGSSKKKKKED---TDRSQSRS 406
Query: 871 PEYTPKSKKYYLHDD---REGEGSDKWVSRGRGRGAFPRGRGR 910
P + ++ + + REG G S G R R R
Sbjct: 407 PSRSVSKEREHAKSESSQREGRGE----SENAGTNQETRSRSR 445
Score = 45.4 bits (106), Expect = 2e-04
Identities = 29/52 (55%), Positives = 35/52 (67%), Gaps = 5/52 (9%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRS 53
SK+ + SRS+SAS++RSRS S+SRS SRS SRSR SRS SRS
Sbjct: 448 SKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSR-----SRSHSRS 494
Score = 44.7 bits (104), Expect = 4e-04
Identities = 27/54 (50%), Positives = 36/54 (66%), Gaps = 5/54 (9%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYS 55
S++N + S SRS S+S S++ S+S+SRSRS SRS SRSRSRS+S
Sbjct: 444 SRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRS-----PSRSRSRSHS 492
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 97.4 bits (241), Expect = 5e-20
Identities = 208/939 (22%), Positives = 336/939 (35%), Gaps = 193/939 (20%)
Query: 2 SKTNKSKSGSRSSRSRSAS-RSRSRSFSKSRSRSRSLSRS-----RKRRLSSRSRSRSYS 55
S ++ S+S S+SRS S RSRS S S SRS SRS SRS R R S RSRS S
Sbjct: 657 SGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRS 716
Query: 56 PAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGR--NRGFYPWGQYNRGGYGNYRS---- 109
++R R+ Y+ R H+R R P FRG+ N+ P G+ R + YR
Sbjct: 717 HGYHRSRSRSPPYR----RYHSRS-RSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPP 771
Query: 110 -----------------------NWQ-NYRQAY-----------SPRRGRSRSR-SPKRR 133
W+ YR+ Y PR +R SP+R
Sbjct: 772 YDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERF 831
Query: 134 SP-----SPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSR 188
P SP +R + S RSR S+ +R +++ + K K+ S++
Sbjct: 832 LPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESEN-- 889
Query: 189 PSQAAGDNQGDEAKE--QTFSGGTSQD-------TKASESSKPWPDATYGTGSASRASAV 239
A GD +G++ K+ + G S+ + +S +P T S +
Sbjct: 890 ---APGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSR 946
Query: 240 SELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQ 299
+ +P P + V + R PK + GS +
Sbjct: 947 DDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKG 1006
Query: 300 GQFD-HGSGSLSPSKKSPVGKS---PPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTE 355
Q G SP + P+ K+ P T +T SS ++ G +K
Sbjct: 1007 PQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGT--------PRKAH 1058
Query: 356 NGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLR 415
+ KE ++T KE+ +K D +KS+ K + K + K L
Sbjct: 1059 SKSAKEHQETKPVKEEKVKKDYSKD-------VKSEKLTTKEEKAK----KPNEKNKPLD 1107
Query: 416 DDFEKKMADFHKEEMDDQDKD-KAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGL 474
+ EK+ K E DKD ++ K S+ + +++++ + ++ E
Sbjct: 1108 NKGEKRK---RKTEEKGVDKDFESSSMKISKLE-----VTEIVKPSPKRKME-------- 1151
Query: 475 VYAPPGKEKQRKTEELEEESFPERSKK----EDRGKR---SEGGHRGFVPEKNFRVTAYK 527
P EK +T E ++ S +KK + GK+ +E P + T+ K
Sbjct: 1152 ----PDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSK 1207
Query: 528 AVQEKSSSPPPRKTSESR---------DKLGAKGDFPTGKSSFSITREAQVNVRMDSFDE 578
QEK RK + + + G P KS + V M+ ++
Sbjct: 1208 VKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNN 1267
Query: 579 DLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQ-------------------- 618
D P A++ + + S + +F S + ++S Q
Sbjct: 1268 DNTAP----AEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPS 1323
Query: 619 -------SQRSPSELFAQHIVTIVHHVKEHHFGSS--------GMTLHERFTKYLKRGTE 663
+ PSE + + H + +H SS G T ++ K E
Sbjct: 1324 NIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPE 1383
Query: 664 QEAAKNKKSPEIHRRID--------ISPSTFRKHGLAHDEMKSPREPGYK--AEGKYKDD 713
+ KN PE +D S S K D+ S R K + K
Sbjct: 1384 KR--KNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKT 1441
Query: 714 PVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRA 773
D R +++ ++ +L R K S + +S + + E+ + KG+ KK
Sbjct: 1442 DYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKK---- 1497
Query: 774 RDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKS 812
S SS S + H +KA T +T+ E T DK+
Sbjct: 1498 ---SNSSPSRDRKPHDHKA---TYDTKRPNEETKSVDKN 1530
Score = 77.4 bits (189), Expect = 6e-14
Identities = 151/764 (19%), Positives = 280/764 (36%), Gaps = 116/764 (15%)
Query: 126 RSRSPKRRSPSPRSRSHSRNSDKSSSDRSR----------RSSSSRSSSNHSRVESSKRK 175
R RSP+ P +++ + +D + S S R + S+S+ H E+ K
Sbjct: 1015 RERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQ--ETKPVK 1072
Query: 176 SAKEKKSSSKDSRPSQAAG---------------DNQGDEAKEQTFSGGTSQDTKASESS 220
K KK SKD + + DN+G++ K +T G +D ++S
Sbjct: 1073 EEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMK 1132
Query: 221 KPWPDATYGTGSASRASAVSELSPRERSP-----ALKSPLQSVVVRRRSPRPSPVPKPSP 275
+ T + + + +R+P +L +P + + + R + +
Sbjct: 1133 ISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKK-------- 1184
Query: 276 PLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPP-----STGSTYGS 330
+ ST + +T +S + + + + G + G S ST ST GS
Sbjct: 1185 -IGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGS 1243
Query: 331 SQKEESAASGGAAYTKRYLEEQKTENGKDKEQ-------KQTNTDK-------EKIKEKG 376
++ + + +EE +N E Q+ DK E +K
Sbjct: 1244 PVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQ 1303
Query: 377 SFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQ-SPKRYKLRDDFEKKMADFHKEEMDDQ-- 433
S G +K+ S P + P + S+ S K K D ++ + +
Sbjct: 1304 PISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSAS 1363
Query: 434 -DKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKS--------GKWEGLVYAPPG---K 481
+K K K R S + E K N Q E++S G ++ L +
Sbjct: 1364 SEKGKTKDRDYSVLEKENPEKRK----NSTQPEKESNLDRLNEQGNFKSLSQSSKEARTS 1419
Query: 482 EKQRKTEELEEESF-PERSKKEDRGKRSEGGHRGFVPEKNFRVTAYK---AVQEKSSSPP 537
+K T + F P R KK D R + EKN +T K + + S+S
Sbjct: 1420 DKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRR-DEKN-ELTRRKDSPSRNKDSASGQ 1477
Query: 538 PRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSG-LLAQERKLCRD 596
K E RD L KG + KS+ S +R+ + + ++D RP+ + ++ C+D
Sbjct: 1478 KNKPREERD-LPKKGTGDSKKSNSSPSRDRKPHDHKATYDTK--RPNEETKSVDKNPCKD 1534
Query: 597 -----LVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLH 651
L N KE + + ++Q ++ Q + V + S
Sbjct: 1535 REKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSS------ 1588
Query: 652 ERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYK 711
R + L R T++ A + P+ + S + ++ + + K ++ + +
Sbjct: 1589 -RLSSDLTRETDEAAFE----PDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESL 1643
Query: 712 DDPVDLRLDIERRKKHKERDLKRGKSRE-----------SVDSRDSSHSRERSAEKTEKT 760
D +++ I R + H + +S S S +S S+++ +K +K
Sbjct: 1644 DTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKK 1703
Query: 761 HKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREE 804
HK KK KKH++ S + H K + ++ E+ +E
Sbjct: 1704 HKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKE 1747
Score = 47.4 bits (111), Expect = 7e-05
Identities = 102/483 (21%), Positives = 170/483 (35%), Gaps = 49/483 (10%)
Query: 107 YRSNWQNYRQAYSPRRGRSRSRS----PKRRSPSPRSRSHSRNSDKSSS----------D 152
YR + ++ SP G S SRS K RS S RSRS+SR+ +S S
Sbjct: 642 YREQRRLKEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPR 701
Query: 153 RSR-RSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTS 211
R R +S + RS S S+ +S ++ S+ P G + K G T
Sbjct: 702 RGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPN---KRNVPQGETE 758
Query: 212 QD--TKASESSKPWPDATYGTGSASRASAVSELSPRERSPALKSPLQSV---VVRRRSPR 266
++ + E P+ Y S + RE + + PR
Sbjct: 759 REYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPR 818
Query: 267 PSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGS 326
PS + P P G + GQ H S ++ + +
Sbjct: 819 PSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQ-SHRSRNIGSNYPEKLSARDGHNQK 877
Query: 327 TYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDG 386
S+++ES + G ++ + +K G++ E N + + K S TG+ +
Sbjct: 878 DNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESE-GFLNPELLETSRK-SREPTGVEEN 935
Query: 387 KMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEF 446
K S P D P R D +++ ++DK KAKG K
Sbjct: 936 KTDSLFVLPSRDDATPVRDEP-------MDAESITFKSVSEKDKRERDKPKAKGDKTKRK 988
Query: 447 DDEPKFMSK--VIGANKNQEEEKSGKWEGLVYAPP----GKEKQRKTEELEEESFPERSK 500
+D K ++ K +E+ G+ E + P KE+ KT+ + S ++ +
Sbjct: 989 NDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDE 1048
Query: 501 K-----EDRGKRSEGGHRGFVPEKNFRVTA-----YKAVQEKSSSPPPRKTSESRDKLGA 550
K +S H+ P K +V K+ + + +K +E L
Sbjct: 1049 KITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDN 1108
Query: 551 KGD 553
KG+
Sbjct: 1109 KGE 1111
Score = 34.7 bits (78), Expect = 0.44
Identities = 24/101 (23%), Positives = 39/101 (38%), Gaps = 18/101 (17%)
Query: 119 SPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSR---------- 168
SP SRS SP ++RSHS ++ + S S++ + H +
Sbjct: 1661 SPSVSPSRSHSPS----GSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKH 1716
Query: 169 ----VESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQT 205
VE K + K KK SK ++ + + + K T
Sbjct: 1717 AGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSVT 1757
Score = 33.9 bits (76), Expect = 0.75
Identities = 51/247 (20%), Positives = 89/247 (36%), Gaps = 42/247 (17%)
Query: 738 RESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTE 797
+E S S S RS+ K+ GS + + + R+ RS S S S + + +
Sbjct: 649 KEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSR 708
Query: 798 ETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARG---RGWGRGNYSGNNNN 854
R S G+ +SR + P R R+R FR + R +G N
Sbjct: 709 NYRSRSRSH-GYHRSRSRSP----PYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFN 763
Query: 855 NSNN---------------DFQ---KRNREEEWDPEYTPKSKKYYL----------HDDR 886
DF+ ++ R EW+ +Y +KYY +R
Sbjct: 764 RYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANR 823
Query: 887 EGEGSDKWVSRGRGRGAFPRGR-----GRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGT 941
E ++++ F RGR G R + + +K S +G + D + +
Sbjct: 824 ENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYP-EKLSARDGHNQKDNTKS 882
Query: 942 ENREEKD 948
+ +E ++
Sbjct: 883 KEKESEN 889
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 97.4 bits (241), Expect = 5e-20
Identities = 208/939 (22%), Positives = 336/939 (35%), Gaps = 193/939 (20%)
Query: 2 SKTNKSKSGSRSSRSRSAS-RSRSRSFSKSRSRSRSLSRS-----RKRRLSSRSRSRSYS 55
S ++ S+S S+SRS S RSRS S S SRS SRS SRS R R S RSRS S
Sbjct: 691 SGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRS 750
Query: 56 PAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGR--NRGFYPWGQYNRGGYGNYRS---- 109
++R R+ Y+ R H+R R P FRG+ N+ P G+ R + YR
Sbjct: 751 HGYHRSRSRSPPYR----RYHSRS-RSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPP 805
Query: 110 -----------------------NWQ-NYRQAY-----------SPRRGRSRSR-SPKRR 133
W+ YR+ Y PR +R SP+R
Sbjct: 806 YDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERF 865
Query: 134 SP-----SPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSR 188
P SP +R + S RSR S+ +R +++ + K K+ S++
Sbjct: 866 LPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESEN-- 923
Query: 189 PSQAAGDNQGDEAKE--QTFSGGTSQD-------TKASESSKPWPDATYGTGSASRASAV 239
A GD +G++ K+ + G S+ + +S +P T S +
Sbjct: 924 ---APGDGKGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSR 980
Query: 240 SELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQ 299
+ +P P + V + R PK + GS +
Sbjct: 981 DDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKG 1040
Query: 300 GQFD-HGSGSLSPSKKSPVGKS---PPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTE 355
Q G SP + P+ K+ P T +T SS ++ G +K
Sbjct: 1041 PQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGT--------PRKAH 1092
Query: 356 NGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLR 415
+ KE ++T KE+ +K D +KS+ K + K + K L
Sbjct: 1093 SKSAKEHQETKPVKEEKVKKDYSKD-------VKSEKLTTKEEKAK----KPNEKNKPLD 1141
Query: 416 DDFEKKMADFHKEEMDDQDKD-KAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGL 474
+ EK+ K E DKD ++ K S+ + +++++ + ++ E
Sbjct: 1142 NKGEKRK---RKTEEKGVDKDFESSSMKISKLE-----VTEIVKPSPKRKME-------- 1185
Query: 475 VYAPPGKEKQRKTEELEEESFPERSKK----EDRGKR---SEGGHRGFVPEKNFRVTAYK 527
P EK +T E ++ S +KK + GK+ +E P + T+ K
Sbjct: 1186 ----PDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSK 1241
Query: 528 AVQEKSSSPPPRKTSESR---------DKLGAKGDFPTGKSSFSITREAQVNVRMDSFDE 578
QEK RK + + + G P KS + V M+ ++
Sbjct: 1242 VKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNN 1301
Query: 579 DLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQ-------------------- 618
D P A++ + + S + +F S + ++S Q
Sbjct: 1302 DNTAP----AEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPS 1357
Query: 619 -------SQRSPSELFAQHIVTIVHHVKEHHFGSS--------GMTLHERFTKYLKRGTE 663
+ PSE + + H + +H SS G T ++ K E
Sbjct: 1358 NIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPE 1417
Query: 664 QEAAKNKKSPEIHRRID--------ISPSTFRKHGLAHDEMKSPREPGYK--AEGKYKDD 713
+ KN PE +D S S K D+ S R K + K
Sbjct: 1418 KR--KNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKT 1475
Query: 714 PVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRA 773
D R +++ ++ +L R K S + +S + + E+ + KG+ KK
Sbjct: 1476 DYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKK---- 1531
Query: 774 RDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKS 812
S SS S + H +KA T +T+ E T DK+
Sbjct: 1532 ---SNSSPSRDRKPHDHKA---TYDTKRPNEETKSVDKN 1564
Score = 77.4 bits (189), Expect = 6e-14
Identities = 151/764 (19%), Positives = 280/764 (36%), Gaps = 116/764 (15%)
Query: 126 RSRSPKRRSPSPRSRSHSRNSDKSSSDRSR----------RSSSSRSSSNHSRVESSKRK 175
R RSP+ P +++ + +D + S S R + S+S+ H E+ K
Sbjct: 1049 RERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQ--ETKPVK 1106
Query: 176 SAKEKKSSSKDSRPSQAAG---------------DNQGDEAKEQTFSGGTSQDTKASESS 220
K KK SKD + + DN+G++ K +T G +D ++S
Sbjct: 1107 EEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMK 1166
Query: 221 KPWPDATYGTGSASRASAVSELSPRERSP-----ALKSPLQSVVVRRRSPRPSPVPKPSP 275
+ T + + + +R+P +L +P + + + R + +
Sbjct: 1167 ISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKK-------- 1218
Query: 276 PLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPP-----STGSTYGS 330
+ ST + +T +S + + + + G + G S ST ST GS
Sbjct: 1219 -IGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGS 1277
Query: 331 SQKEESAASGGAAYTKRYLEEQKTENGKDKEQ-------KQTNTDK-------EKIKEKG 376
++ + + +EE +N E Q+ DK E +K
Sbjct: 1278 PVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQ 1337
Query: 377 SFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQ-SPKRYKLRDDFEKKMADFHKEEMDDQ-- 433
S G +K+ S P + P + S+ S K K D ++ + +
Sbjct: 1338 PISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSAS 1397
Query: 434 -DKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKS--------GKWEGLVYAPPG---K 481
+K K K R S + E K N Q E++S G ++ L +
Sbjct: 1398 SEKGKTKDRDYSVLEKENPEKRK----NSTQPEKESNLDRLNEQGNFKSLSQSSKEARTS 1453
Query: 482 EKQRKTEELEEESF-PERSKKEDRGKRSEGGHRGFVPEKNFRVTAYK---AVQEKSSSPP 537
+K T + F P R KK D R + EKN +T K + + S+S
Sbjct: 1454 DKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRR-DEKN-ELTRRKDSPSRNKDSASGQ 1511
Query: 538 PRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSG-LLAQERKLCRD 596
K E RD L KG + KS+ S +R+ + + ++D RP+ + ++ C+D
Sbjct: 1512 KNKPREERD-LPKKGTGDSKKSNSSPSRDRKPHDHKATYDTK--RPNEETKSVDKNPCKD 1568
Query: 597 -----LVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLH 651
L N KE + + ++Q ++ Q + V + S
Sbjct: 1569 REKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSS------ 1622
Query: 652 ERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYK 711
R + L R T++ A + P+ + S + ++ + + K ++ + +
Sbjct: 1623 -RLSSDLTRETDEAAFE----PDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESL 1677
Query: 712 DDPVDLRLDIERRKKHKERDLKRGKSRE-----------SVDSRDSSHSRERSAEKTEKT 760
D +++ I R + H + +S S S +S S+++ +K +K
Sbjct: 1678 DTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKK 1737
Query: 761 HKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREE 804
HK KK KKH++ S + H K + ++ E+ +E
Sbjct: 1738 HKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKE 1781
Score = 43.5 bits (101), Expect = 0.001
Identities = 100/479 (20%), Positives = 166/479 (34%), Gaps = 59/479 (12%)
Query: 121 RRGRSRSRSP--------------KRRSPSPRSRSHSRNSDKSSS----------DRSR- 155
RR SRS+SP K RS S RSRS+SR+ +S S R R
Sbjct: 680 RRSFSRSKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRG 739
Query: 156 RSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQD-- 213
+S + RS S S+ +S ++ S+ P G + K G T ++
Sbjct: 740 KSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPN---KRNVPQGETEREYF 796
Query: 214 TKASESSKPWPDATYGTGSASRASAVSELSPRERSPALKSPLQSV---VVRRRSPRPSPV 270
+ E P+ Y S + RE + + PRPS
Sbjct: 797 NRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSAN 856
Query: 271 PKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGS 330
+ P P G + GQ H S ++ + +
Sbjct: 857 RENFSPERFLPLNIRNSPFTRGRREDYVGGQ-SHRSRNIGSNYPEKLSARDGHNQKDNTK 915
Query: 331 SQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKS 390
S+++ES + G ++ + +K G++ E N + + K S TG+ + K S
Sbjct: 916 SKEKESENAPGDGKGNKHKKHRKRRKGEESE-GFLNPELLETSRK-SREPTGVEENKTDS 973
Query: 391 DSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEP 450
P D P R D +++ ++DK KAKG K +D
Sbjct: 974 LFVLPSRDDATPVRDEP-------MDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGS 1026
Query: 451 KFMSK--VIGANKNQEEEKSGKWEGLVYAPP----GKEKQRKTEELEEESFPERSKK--- 501
K ++ K +E+ G+ E + P KE+ KT+ + S ++ +K
Sbjct: 1027 AVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITG 1086
Query: 502 --EDRGKRSEGGHRGFVPEKNFRVTA-----YKAVQEKSSSPPPRKTSESRDKLGAKGD 553
+S H+ P K +V K+ + + +K +E L KG+
Sbjct: 1087 TPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGE 1145
Score = 37.4 bits (85), Expect = 0.067
Identities = 58/264 (21%), Positives = 99/264 (37%), Gaps = 46/264 (17%)
Query: 721 IERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSS 780
+E +K KER +R SR SS+SR S+ K+ GS + + + R+ RS S
Sbjct: 670 MEYKKIQKER--RRSFSRSKSPYSGSSYSR--SSYTYSKSRSGSTRSRSYSRSFSRSHSR 725
Query: 781 SSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARG 840
S S + + + R S G+ +SR + P R R+R FR +
Sbjct: 726 SYSRSPPYPRRGRGKSRNYRSRSRSH-GYHRSRSRSP----PYRRYHSRSRSPQAFRGQS 780
Query: 841 ---RGWGRGNYSGNNNNNSNN---------------DFQ---KRNREEEWDPEYTPKSKK 879
R +G N DF+ ++ R EW+ +Y +K
Sbjct: 781 PNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWERKYREWYEK 840
Query: 880 YYL----------HDDREGEGSDKWVSRGRGRGAFPRGR-----GRFMFRKSSTSPKWAH 924
YY +RE ++++ F RGR G R + +
Sbjct: 841 YYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYP- 899
Query: 925 DKFSGEEGEIEDDESGTENREEKD 948
+K S +G + D + ++ +E ++
Sbjct: 900 EKLSARDGHNQKDNTKSKEKESEN 923
Score = 35.0 bits (79), Expect = 0.33
Identities = 33/127 (25%), Positives = 53/127 (41%), Gaps = 9/127 (7%)
Query: 738 RESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTE 797
RE ++ + + E T K + KK ++ R RS S S S S SY YT
Sbjct: 643 REQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQKERRRSFSRSKSPYSGSSYSRSSYT- 701
Query: 798 ETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSN 857
+S +G +SR ++ F R R+ + RGRG R NY + ++
Sbjct: 702 ----YSKSRSGSTRSRSYSRSFSRSHSRSYSRSP---PYPRRGRGKSR-NYRSRSRSHGY 753
Query: 858 NDFQKRN 864
+ + R+
Sbjct: 754 HRSRSRS 760
Score = 34.7 bits (78), Expect = 0.44
Identities = 24/101 (23%), Positives = 39/101 (38%), Gaps = 18/101 (17%)
Query: 119 SPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSR---------- 168
SP SRS SP ++RSHS ++ + S S++ + H +
Sbjct: 1695 SPSVSPSRSHSPS----GSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKH 1750
Query: 169 ----VESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQT 205
VE K + K KK SK ++ + + + K T
Sbjct: 1751 AGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSVT 1791
Score = 32.7 bits (73), Expect = 1.7
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 9/119 (7%)
Query: 730 RDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSR---SSSSSSQS 786
R+ +R K E S+ + + + E E K QK+ RR+ RS+ S SS S+S
Sbjct: 643 REQRRLKEEEKKKSKLDEFTNDFAKELMEY----KKIQKERRRSFSRSKSPYSGSSYSRS 698
Query: 787 SHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARGRGWGR 845
S++Y ++ + T R S + F +S + P R G ++ R+R G+ R
Sbjct: 699 SYTY-SKSRSGSTRSRSYSRS-FSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHR 755
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 87.0 bits (214), Expect = 7e-17
Identities = 85/302 (28%), Positives = 135/302 (44%), Gaps = 19/302 (6%)
Query: 3 KTNKSKSGSRS-----SRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPA 57
++ +S+SGS + SRSRS +++R RS S+S ++R SRSR +R SRS SP
Sbjct: 386 ESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPN-KARDCSRSRSPY 444
Query: 58 HNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQA 117
R+R+ R R H+R R P R R+R P + + G+ S +++R++
Sbjct: 445 KARDRSRSR--SPNKARDHSRS-RSPNKARDRSRSRSPSKERDHSQLGS-PSKERDHRRS 500
Query: 118 YSPRRGR----SRSRSPKR-----RSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSR 168
SP + R SRS S +R RSPS + S DRS+ S S +
Sbjct: 501 RSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQS 560
Query: 169 VESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATY 228
SK + + +S SK+ Q+ ++ + S ++ SSK +
Sbjct: 561 RSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRS 620
Query: 229 GTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLP 288
T S + S S +E P+ + +S +R R S + + P ++S ST P
Sbjct: 621 RTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFP 680
Query: 289 SG 290
SG
Sbjct: 681 SG 682
Score = 79.3 bits (194), Expect = 2e-14
Identities = 160/705 (22%), Positives = 259/705 (36%), Gaps = 107/705 (15%)
Query: 120 PRRGRSRSRSPKRRSPSPRSRSHSRNS--DKSSSDRSRRSSSSRSSSNHSRVESSKRKSA 177
P +S + RS P + SRNS SSS ++ +S+ R+ SN S R A
Sbjct: 29 PASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKA 88
Query: 178 KEKKSSSKDSRPSQAA-GDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRA 236
+ S D+R S+A+ + + T S G + + S SSK P SRA
Sbjct: 89 RTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSP---------SRA 139
Query: 237 SAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSG 296
S + P + S R R+P TSQ + G
Sbjct: 140 STPGRIRTHGARPGMAS-------RVRTP--------------TSQQKGSRGKSYGRPRT 178
Query: 297 THQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYL-EEQKTE 355
+++ + D +LS P G GS G S + S T + ++K++
Sbjct: 179 SNRERSDSQPRNLSKKSYRPPG------GSGIGRSSELAVTPSTAKCQTPTGIPSKEKSD 232
Query: 356 NGKDKEQKQTNTDKEKI---KEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRY 412
N ++ + + I +EK S+S T + ++KS + A + S+SP+R
Sbjct: 233 NPSPSSSRKVKSYGQMIIPSREK-SYSPTEMSS-RVKSYNQASTRSRPQSHSQSRSPRRS 290
Query: 413 KLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWE 472
R +K+ + ++ +A+ R K + +G + GK +
Sbjct: 291 --RSGSQKRTHSRVRSHSWKRNHSRARSRTR-------KGILSQMGRHSQSRSHSKGKSQ 341
Query: 473 GLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFV-PEKNFRVTAYKAVQE 531
P ++ ++ ERS R E HRG P K + + +
Sbjct: 342 NQSRTP----RRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNK 397
Query: 532 KSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARP-SGLLAQE 590
+ R +++RD+ ++ + S S R + D +R S A++
Sbjct: 398 QRDHSRSRSPNKARDRSRSRSPYKARDRSRS---------RSPNKARDCSRSRSPYKARD 448
Query: 591 RKLCRDLVHSNKKEQEFRSIFQHIQSAQSQ-RSPSELFAQHIVTIVHHVKEHHFGSSGMT 649
R R NK RS + +S+ RSPS KE G
Sbjct: 449 RSRSRS---PNKARDHSRSRSPNKARDRSRSRSPS--------------KERDHSQLGSP 491
Query: 650 LHERFTKYLKRGTEQEAAKNKKSPEIHR--RIDISPSTFRKHGLAHDEMKSPREPGYKAE 707
ER + + +++ + +S R R SPS R+ + R P + +
Sbjct: 492 SKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQR-------RQSRSPNKERD 544
Query: 708 GKYKDDPVDLRLDIERRKKHKERDLKR----GKSRESVDSRDSS----HSRERSAEKTE- 758
P + R + R KERD +R K RE SR SS HSR RS K
Sbjct: 545 RSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSG 604
Query: 759 -KTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEER 802
+ S K+K H R+R S+ + SQS S K + ++ T R
Sbjct: 605 YSRPRASSKEKAHSRSRTPSK-EGNHSQSRTSSKESDPSQSTVPR 648
Score = 76.6 bits (187), Expect = 1e-13
Identities = 130/574 (22%), Positives = 215/574 (37%), Gaps = 108/574 (18%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRE 61
SK+ KS S R+ +R +SRSR R SK+R+ SR + +R + S S
Sbjct: 62 SKSTKSTSTKRAPSNRPSSRSRVR--SKARTPSRVSTDTRTSKASKAS------------ 107
Query: 62 RNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPR 121
D R H RR + RGR G R
Sbjct: 108 ----------DVRCHQ---RRGTHSRGRTPG----------------------------R 126
Query: 122 RG-RSRSRSPKRRSPSPRSRSHSRNSDKSSSDR---SRRSSSSRSSSNHSRVESSKRKSA 177
RG RS RSP R S R R+H +S R S++ S S R + +R +
Sbjct: 127 RGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDS 186
Query: 178 KEKKSSSKDSRPSQAAGDNQGDE-------AKEQTFSGGTSQDTKASESSKPWPDATYGT 230
+ + S K RP +G + E AK QT +G S++ +S P P ++
Sbjct: 187 QPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKE----KSDNPSPSSSRKV 242
Query: 231 GSASR---ASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTL 287
S + S SP E S +KS Q+ S R P S SQ S
Sbjct: 243 KSYGQMIIPSREKSYSPTEMSSRVKSYNQA------STRSRP--------QSHSQSRSPR 288
Query: 288 PSGAGYQSGTHQGQFDHG-----SGSLSPSKK---SPVGKSPPSTGSTYGSSQKEESAAS 339
S +G Q TH H S + S ++K S +G+ S + G SQ +
Sbjct: 289 RSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPR 348
Query: 340 GGAA--YTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKT 397
G + +++ +E+ + + +++ + +++ S +G K + S +
Sbjct: 349 RGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSG-SPNKQRDHSRSRSP 407
Query: 398 DSEKPFRGSQSPKRYKLRDDFE----KKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFM 453
+ + S+SP YK RD K D + + +D+++ R ++ D +
Sbjct: 408 NKARDRSRSRSP--YKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSR 465
Query: 454 SKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGH- 512
S ++++ S + + P KE+ + + ER ++ R E H
Sbjct: 466 SPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSK---ERQCRQSRSSSKERDHR 522
Query: 513 RGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRD 546
R P K + ++ ++ R SE R+
Sbjct: 523 RSRSPSKERQRRQSRSPNKERDRSQSRSPSEERE 556
Score = 64.3 bits (155), Expect = 5e-10
Identities = 63/219 (28%), Positives = 92/219 (42%), Gaps = 31/219 (14%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRE 61
S++ + R SRS + R RS+S S S R SRS + R R R SP+ RE
Sbjct: 524 SRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSK---ERDRRRWRSPSKERE 580
Query: 62 RNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPR 121
R R + + R H+R R N+ + GY R A S
Sbjct: 581 RRQSR--SSSEERDHSRS-------RSPNK---------QSGYSRPR--------ASSKE 614
Query: 122 RGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKK 181
+ SRSR+P + +SR+ S+ SD S S R RS + S + S+ ++ +
Sbjct: 615 KAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSL--SQNRTPSKTS 672
Query: 182 SSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESS 220
S S + PS +Q D + T S T ++S SS
Sbjct: 673 SHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSS 711
Score = 57.4 bits (137), Expect = 6e-08
Identities = 153/713 (21%), Positives = 253/713 (35%), Gaps = 92/713 (12%)
Query: 248 SPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSG 307
SP S + S P+ PKP L ST S P+ + + + S
Sbjct: 3 SPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTK---SATPNRSLVPTKPATSRNSVMSP 59
Query: 308 SLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNT 367
S S S KS K PS + S + ++ + R + K + + +++ T++
Sbjct: 60 SSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHS 119
Query: 368 DKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHK 427
+GS S K T G++ ++R ++ K
Sbjct: 120 RGRTPGRRGSRSS--------KRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGK 171
Query: 428 EEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKT 487
+ + R+ S D +P+ +SK + + G+ L P + Q T
Sbjct: 172 S----YGRPRTSNRERS--DSQPRNLSKK--SYRPPGGSGIGRSSELAVTPSTAKCQTPT 223
Query: 488 EELEEESFPERSKKEDRGKRSEGGHRGFVP--EKNFRVTAY----KAVQEKSSSPPPRKT 541
+E S R +S G + +P EK++ T K+ + S+ P+
Sbjct: 224 GIPSKEKSDNPSPSSSRKVKSYG--QMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSH 281
Query: 542 SESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARP-----SGLLAQERKLCRD 596
S+SR +S + VR S+ + +R G+L+Q + +
Sbjct: 282 SQSRSPR---------RSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQS 332
Query: 597 LVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTK 656
HS K Q + +S R+PS+ H + + H GSS +
Sbjct: 333 RSHSKGKSQNQSRTPRRGRSHNWSRNPSKE-RSHSHSRSSSKERDHRGSS--------SP 383
Query: 657 YLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVD 716
+ G Q + NK+ R SP+ A D +S R P YKA + + +
Sbjct: 384 RKESGRSQSGSPNKQRDHSRSR---SPNK------ARDRSRS-RSP-YKARDRSRSRSPN 432
Query: 717 LRLDIER-RKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARD 775
D R R +K RD R +SR +RD HSR RS K ARD
Sbjct: 433 KARDCSRSRSPYKARD--RSRSRSPNKARD--HSRSRSPNK----------------ARD 472
Query: 776 RSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQ 835
RSRS S S + HS E R S + K R + ER R+R +
Sbjct: 473 RSRSRSPSKERDHSQLGSPSKERDHRRSRSPS---KERQCRQSRSSSKERDHRRSRSPSK 529
Query: 836 FRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDKWV 895
R R + R + + S + ++R + P + ++ + +E E
Sbjct: 530 ERQRRQ--SRSPNKERDRSQSRSPSEEREHRQSRSPS-KERDRRRWRSPSKERERRQSRS 586
Query: 896 S---RGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENRE 945
S R R P + + ++S+ K AH + E +S T ++E
Sbjct: 587 SSEERDHSRSRSPNKQSGYSRPRASSKEK-AHSRSRTPSKEGNHSQSRTSSKE 638
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 86.7 bits (213), Expect = 1e-16
Identities = 134/604 (22%), Positives = 216/604 (35%), Gaps = 97/604 (16%)
Query: 15 RSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQNRDFR 74
R R R R + R R R R R+RR R R R + R+R + R R
Sbjct: 402 RERERERERENR-QRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKR 460
Query: 75 GHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRS------- 127
R R R + + G RS RQA P++ + +
Sbjct: 461 DEKDRQHRD---RDREKE-----REKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRA 512
Query: 128 ---RSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSS 184
+ P RRS SP+ + S + R + S+SS S+SN SR SS R S+ SS
Sbjct: 513 DEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSR--SSSRSSSYSGSGSS 570
Query: 185 KDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSP 244
+ S + ++ +FSG S+ S S P P + S +
Sbjct: 571 RSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPG 630
Query: 245 RERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLP----------SGAGYQ 294
+ ++K P + + +PVP+P+ P P SG+G
Sbjct: 631 KAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSG 690
Query: 295 SGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKT 354
SG+ S SLS S S V + S+ S + ++ A
Sbjct: 691 SGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLA-----------SPV 739
Query: 355 ENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRG---SQSPKR 411
+ + T KEK K K + G+ + K K DS S KP G SQ P
Sbjct: 740 SSASSRSPAPAQTRKEKGKSK---KEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPST 796
Query: 412 YKLRDDFEKKMADF--HKE-EMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKS 468
+ + + F HKE ++ +K KG ++
Sbjct: 797 PQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKR------------------------ 832
Query: 469 GKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGF-VPEK----NFRV 523
Y P K++Q + P+R ++ R GG G PE+ N +
Sbjct: 833 -------YEPSDKDRQSPPPAKRPNTSPDRGSRD----RKSGGRLGSPKPERQRGQNSKA 881
Query: 524 TAYKAVQEKSSSPPPRKTSESRDKLGAKGD-----FPTGKSSFSITREAQVNVRMDSFDE 578
A A +++ SP + +S+ G D +GK+S +++R ++ ++ + ++
Sbjct: 882 PAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKAS-TLSRREELLKQLKAVED 940
Query: 579 DLAR 582
+AR
Sbjct: 941 AIAR 944
Score = 63.2 bits (152), Expect = 1e-09
Identities = 114/528 (21%), Positives = 171/528 (32%), Gaps = 92/528 (17%)
Query: 80 YRRPYYFRGRNRGFYPWGQYNRGG-YGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPR 138
Y PYY Y ++ RGG Y N+R + + Y R R R R + R R
Sbjct: 367 YADPYYD-------YEIERFWRGGQYENFRVQYTE-TEPYHNYRERERERERENRQ---R 415
Query: 139 SRSHSRNSDKSSSDRSRRSSSSRSSSNHSR-VESSKRKSAKEKKSSSKDSRPSQAAG-DN 196
R R D+ +R RR H R E +RK E++ + +D + Q D
Sbjct: 416 ERERERERDR---ERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDR 472
Query: 197 QGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPRERSPALKSPLQ 256
+ + KE+ S + ++ P +A RA + R +SP K +
Sbjct: 473 EKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVS 532
Query: 257 SVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAG----------YQS-GTHQGQFDHG 305
R R R + S SS S S+ SG+G Y S + +
Sbjct: 533 VSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSF 592
Query: 306 SGSLSPSKKSPVGKSPPSTGSTYGSS--QKEESAASGGAAYTKRYLE------------- 350
SGS S S+ SP T S + S K E A G A K +
Sbjct: 593 SGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKT 652
Query: 351 ----EQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGK------------------- 387
+ T+ G +E ++ + + S +G G G
Sbjct: 653 TAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSS 712
Query: 388 ----MKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKE 443
S S A DSE + SP K + +D K + RK
Sbjct: 713 VSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKR 772
Query: 444 SEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKED 503
PK G +Q+ + APPG+ +Q +E +K D
Sbjct: 773 DSSTQPPKSAKPPAGGKSSQQPSTPQQ------APPGQPQQGTFVAHKEIKLTLLNKAAD 826
Query: 504 RGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAK 551
+G R Y+ + SPPP K + G++
Sbjct: 827 KGSRKR----------------YEPSDKDRQSPPPAKRPNTSPDRGSR 858
Score = 57.0 bits (136), Expect = 8e-08
Identities = 104/413 (25%), Positives = 161/413 (38%), Gaps = 56/413 (13%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSY----SPA 57
S +N S+S SRSS + SRSRS S S S S S SRSRSRS+ SP+
Sbjct: 550 SASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPS 609
Query: 58 HNRERNHPRVYQNRD-----FRGHNRGYRRPYYFRG---RNRGFYPWGQYNRGGYGNYRS 109
+ P + + + + ++P + P + + G+ R
Sbjct: 610 PTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKP--GDPRE 667
Query: 110 NWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRV 169
+ R A +P R R+ S S S S S S SR+ S S S SS++ SSS+ V
Sbjct: 668 ARRKERPARTPPRRRTLSGSGS-GSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSV 726
Query: 170 ESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYG 229
+S + SS SR S A + ++ K + G + K S++P A
Sbjct: 727 DSEDMYADLASPVSSASSR-SPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPP 785
Query: 230 TGSASRASAVSELSPRERSPALKSPLQSVVV-----------------RRRSPRPSPVPK 272
G S+ +P++ P P Q V R+ PS +
Sbjct: 786 AGG---KSSQQPSTPQQAPPG--QPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDR 840
Query: 273 PSPPLS---STSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPS-------KKSPVGKSPP 322
SPP + +TS + +G + G+ + + G S +P+ + SP KS
Sbjct: 841 QSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSS 900
Query: 323 STGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEK 375
S G A+ GAA TK + T + +++ KQ ++ I K
Sbjct: 901 KVTSVPG------KASDPGAASTKS--GKASTLSRREELLKQLKAVEDAIARK 945
Score = 43.1 bits (100), Expect = 0.001
Identities = 60/276 (21%), Positives = 98/276 (35%), Gaps = 25/276 (9%)
Query: 7 SKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSY----SPAHNRER 62
S SGS S S S S SRSRS S S S S + S S Y SP +
Sbjct: 685 SGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASS 744
Query: 63 NHPRVYQNRDFRGHNR---GYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYS 119
P Q R +G ++ G + R + + GG + + +
Sbjct: 745 RSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQ 804
Query: 120 PRRGRSRSRSP-------KRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESS 172
P++G + K R R + D+ S ++R ++S + R
Sbjct: 805 PQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGG 864
Query: 173 KRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGS 232
+ S K ++ ++S+ A D + S +K+S P G+
Sbjct: 865 RLGSPKPERQRGQNSKAPAAPADRKRQ----------LSPQSKSSSKVTSVPGKASDPGA 914
Query: 233 AS-RASAVSELSPRERSPALKSPLQSVVVRRRSPRP 267
AS ++ S LS RE ++ + R+R+ P
Sbjct: 915 ASTKSGKASTLSRREELLKQLKAVEDAIARKRAKIP 950
Score = 40.4 bits (93), Expect = 0.008
Identities = 42/202 (20%), Positives = 76/202 (37%), Gaps = 15/202 (7%)
Query: 724 RKKHKERDLKRGK-SRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSS 782
R++ +ERD +R + RE R+ +ER K E + +K+ +K R+ RDR R
Sbjct: 417 RERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKER 476
Query: 783 SSQSS----HSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRA 838
+ S + E ++E +TTG R + + G +
Sbjct: 477 EKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPS 536
Query: 839 RGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDKWVSRG 898
R R R + ++ +++N + +R + + +S+ + SR
Sbjct: 537 RAR---RRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRS-------RSSSYSSYSSRS 586
Query: 899 RGRGAFPRGRGRFMFRKSSTSP 920
+F R R SS SP
Sbjct: 587 SRHSSFSGSRSRSRSFSSSPSP 608
Score = 40.4 bits (93), Expect = 0.008
Identities = 38/154 (24%), Positives = 61/154 (39%), Gaps = 8/154 (5%)
Query: 651 HERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKY 710
HER + +R E E + K+ + + D R+ + +SP+ P +AE
Sbjct: 440 HERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPK 499
Query: 711 KDDPV--------DLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHK 762
K+ D D RR K ++ L S R + + SA + ++
Sbjct: 500 KEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSS 559
Query: 763 GSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYT 796
S +R RSRSSS SS SS S + ++
Sbjct: 560 RSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFS 593
Score = 37.0 bits (84), Expect = 0.088
Identities = 89/427 (20%), Positives = 146/427 (34%), Gaps = 57/427 (13%)
Query: 1 MSKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYS---PA 57
+ + ++ K R S+S S S S++R R ++ + S SSRS SRS S
Sbjct: 509 VKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSG 568
Query: 58 HNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGY-GNYRSNWQNYRQ 116
+R R+ Y + R R R+ P + + R+ +
Sbjct: 569 SSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEP--- 625
Query: 117 AYSPRRGRSRSRSPKRRSPSPRSRSHSRNS------DKSSSDRS--RRSSSSRSSSNHSR 168
+P G++ +S K+ +P P ++ + K R R+ +R+
Sbjct: 626 --APPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRT 683
Query: 169 VESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATY 228
+ S S SS SR + + A +S + +S + D
Sbjct: 684 LSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSAT------SSSSSAHSVDSEDMYADLAS 737
Query: 229 GTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLP 288
SAS S + +E+ + K R+R P PP S + P
Sbjct: 738 PVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTP 797
Query: 289 SGAGYQSGTHQGQF---------------DHGSGS-LSPSKK---SPVGKSPPSTGSTYG 329
A QG F D GS PS K SP P+T G
Sbjct: 798 QQAP-PGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRG 856
Query: 330 SSQKEESAASGGAAYTKRYLEEQKTENGK------DKEQK---QTNTDKEKIKEKGSFSD 380
S ++ SGG + + E Q+ +N K D++++ Q+ + + G SD
Sbjct: 857 SRDRK----SGGRLGSPK-PERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASD 911
Query: 381 TGLGDGK 387
G K
Sbjct: 912 PGAASTK 918
Score = 34.7 bits (78), Expect = 0.44
Identities = 15/61 (24%), Positives = 28/61 (45%)
Query: 744 RDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEERE 803
R+ RER + E+ + + +++ RR R+R R + EE+ E +R+
Sbjct: 402 RERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRD 461
Query: 804 E 804
E
Sbjct: 462 E 462
Score = 33.1 bits (74), Expect = 1.3
Identities = 23/95 (24%), Positives = 44/95 (46%), Gaps = 5/95 (5%)
Query: 722 ERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSS 781
E H R+ +R + RE+ R+ RER E+ E+ + +++++H R ++R R
Sbjct: 394 ETEPYHNYREREREREREN-RQRERERERERDRER-ERRQREREREREHERDKERQRRKE 451
Query: 782 --SSSQSSHSYKAEEYTEETEERE-ESTTGFDKSR 813
++ K ++ + E+E E G K R
Sbjct: 452 EWERERAKRDEKDRQHRDRDREKEREKEKGKPKPR 486
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 84.3 bits (207), Expect = 5e-16
Identities = 183/889 (20%), Positives = 327/889 (36%), Gaps = 178/889 (20%)
Query: 4 TNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERN 63
+++S S SRSRS SRSRS S S +RSRS + S SR R SSRS SR N+ +
Sbjct: 682 SDRSSESSPRSRSRS-SRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSR------NKYSD 734
Query: 64 HPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRG 123
H + ++ + + R R R+ G + + + ++ Y +G
Sbjct: 735 HSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKY------VKG 788
Query: 124 RSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSS 183
R RS ++ S S S +S +S++SS ++ + R + + K+ E+KS
Sbjct: 789 RDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSK 848
Query: 184 SKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELS 243
S+ P +K++T S + SKP G+ S +++ +++
Sbjct: 849 SERECP----------HSKKRTLKENLSDHLR--NGSKPKRKNYAGSKWDSESNSERDVT 896
Query: 244 PRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFD 303
++ S P SS + G S H
Sbjct: 897 KNSKN------------------------DSHP-SSDKEEGEATSDSESEVSEIHI---- 927
Query: 304 HGSGSLSPSKKSPVGKS-PPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQ 362
+ P+ KS S P G+ S Q+ ++ S G+ +EN + K Q
Sbjct: 928 ----KVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSC--------SNSENNRGKPQ 975
Query: 363 KQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKM 422
K + KE +K + + GK APK K Q P +
Sbjct: 976 KHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPK---RKQAFHWQPPLEF---------- 1022
Query: 423 ADFHKEEMDD-QDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYA---- 477
+ +EE+DD Q ++K +K SE ++ K ++ K+ EE+ SGK + + +
Sbjct: 1023 GEEEEEEIDDKQVTQESKEKKVSENNETIK--DNILKTEKSSEEDLSGKHDTVTVSSDLD 1080
Query: 478 -----------------------------------PPGKEKQRKTEELEEESFPERSKKE 502
P G E +T++ E P+RS
Sbjct: 1081 QFTKDDSKLSISPTALNTEENVACLQNIQHVEESVPNGVEDVLQTDDNMEICTPDRSSPA 1140
Query: 503 DRGKRSE-GGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDK-LGAKGDFPTGKSS 560
+ S G R P+ N + A + + +++S S K LG G + +S
Sbjct: 1141 KVEETSPLGNARLDTPDINIVLKQDMATEHPQAEVVKQESSMSESKVLGEVGKQDSSSAS 1200
Query: 561 FSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQ 620
+ E+ + +++A S + N +++++ + A
Sbjct: 1201 LASAGES-------TGKKEVAEKSQI--------------NLIDKKWKPLQGVGNLAAPN 1239
Query: 621 RSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRID 680
+ S ++T V +K G+ + + ++ G+ + +K+ ++RR
Sbjct: 1240 AATSSAVEVKVLTTVPEMK-----PQGLRIEIKSKNKVRPGSLFDEV--RKTARLNRRPR 1292
Query: 681 ISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRES 740
S+ + + D+ R P R E + +H+ R + SR
Sbjct: 1293 NQESSSDEQTPSRDDDSQSRSPSRS------------RSKSETKSRHRTRSVSYSHSR-- 1338
Query: 741 VDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETE 800
S SR ++ +++ S+ + + R R RSRSS S SYK+ + +
Sbjct: 1339 ------SRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSS-----SYRSYKSHRTSSRSR 1387
Query: 801 EREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARGRGWGRGNYS 849
R S +SR T D R R++ + + RGR + R + S
Sbjct: 1388 SRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYH-RGRSYNRRSRS 1435
Score = 75.9 bits (185), Expect = 2e-13
Identities = 187/948 (19%), Positives = 334/948 (35%), Gaps = 160/948 (16%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRE 61
SK++ SSRSR+AS+S S S S+S+SRS S S RKR S ++ S +
Sbjct: 521 SKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPV 580
Query: 62 RNHP---RVYQNRDF----------------------------RGHNRGYRRPYYFRGRN 90
+ P + QN + + Y R + +
Sbjct: 581 KTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKT 640
Query: 91 RGFYPWGQY----------NRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSR 140
P + Y N ++ + YS RS SP+ RS S RSR
Sbjct: 641 THLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSR 700
Query: 141 SHSRNSDKS----SSDRSRRSSSSRS--------------SSNHSRVESSKRKSAKEK-K 181
S+SR+ +S SS RS SSRS SS+++ + S + AK + +
Sbjct: 701 SYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLR 760
Query: 182 SSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSE 241
SS K + S + ++ + G + + + S+ Y + S + ++
Sbjct: 761 SSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQ 820
Query: 242 LSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTS---QMGSTLPSGAGYQSGTH 298
+ + + + R S + P + + L +G+ + +
Sbjct: 821 SAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNY 880
Query: 299 QG-QFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKT--- 354
G ++D S S K+ S PS+ G + + + + + T
Sbjct: 881 AGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTS 940
Query: 355 ---ENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKR 411
+NG K KQ + + +GS S++ GK + K + ++ K
Sbjct: 941 LPDDNGAWKSSKQRTSTSD---SEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKL 997
Query: 412 YKLRD---DFEKKMADFH-----------KEEMDD-QDKDKAKGRKESEFDDEPKFMSKV 456
+D K+ FH +EE+DD Q ++K +K SE ++ K +
Sbjct: 998 KGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIK--DNI 1055
Query: 457 IGANKNQEEEKSGKWEGLVYA--------------------------------------- 477
+ K+ EE+ SGK + + +
Sbjct: 1056 LKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDSKLSISPTALNTEENVACLQNIQHVEESV 1115
Query: 478 PPGKEKQRKTEELEEESFPERSKKEDRGKRSE-GGHRGFVPEKNFRVTAYKAVQEKSSSP 536
P G E +T++ E P+RS + S G R P+ N + A + +
Sbjct: 1116 PNGVEDVLQTDDNMEICTPDRSSPAKVEETSPLGNARLDTPDINIVLKQDMATEHPQAEV 1175
Query: 537 PPRKTSESRDK-LGAKGDFPTGKSSFS----------ITREAQVNVRMDSFDE-----DL 580
+++S S K LG G + +S + + ++Q+N+ + +L
Sbjct: 1176 VKQESSMSESKVLGEVGKQDSSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNL 1235
Query: 581 ARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTI-VHHVK 639
A P+ + ++ V + E + + + I+S R P LF + T ++
Sbjct: 1236 AAPNAATSSAVEV---KVLTTVPEMKPQGLRIEIKSKNKVR-PGSLFDEVRKTARLNRRP 1291
Query: 640 EHHFGSSGMTLHERFTKYLKRGTEQEAAKNK-KSPEIHRRIDISPSTFRKHGLAHD---- 694
+ SS R R + +K++ KS R + S S R
Sbjct: 1292 RNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSR 1351
Query: 695 EMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRG---KSRESVDSRDSSHSRE 751
R G+ + G+ + R R + R SR + DS +SR
Sbjct: 1352 SYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRS 1411
Query: 752 RSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEET 799
RS +++++ + + +RR+R RS S S+S SY E+
Sbjct: 1412 RSRSRSQRSDSYHRGRSYNRRSRS-CRSYGSDSESDRSYSHHRSPSES 1458
Score = 73.6 bits (179), Expect = 8e-13
Identities = 66/185 (35%), Positives = 88/185 (47%), Gaps = 29/185 (15%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSL----SRSRKRRLSSRSRSRSYSPA 57
S ++ S S+SRS SRSRS+S +KSR R+RS+ SRSR R +S RSRSYS +
Sbjct: 1297 SSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRS 1356
Query: 58 -----HNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQ 112
++R R R R ++ H R R R+ + P + Y +Y S
Sbjct: 1357 RSRGWYSRGRTRSRSSSYRSYKSHRTSSRS----RSRSSSYDPHSRSRSYTYDSYYS--- 1409
Query: 113 NYRQAYSPRRGRSRSRSPKRRSPS-PRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVES 171
RSRSRS +RS S R RS++R S +S S S RS S+H
Sbjct: 1410 -----------RSRSRSRSQRSDSYHRGRSYNRRS-RSCRSYGSDSESDRSYSHHRSPSE 1457
Query: 172 SKRKS 176
S R S
Sbjct: 1458 SSRYS 1462
Score = 67.0 bits (162), Expect = 8e-11
Identities = 172/862 (19%), Positives = 288/862 (33%), Gaps = 167/862 (19%)
Query: 131 KRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPS 190
KR+ P+ HS SD SS+ S SSS S H R S+R+ K + + +
Sbjct: 188 KRKKPT-----HSEGSDSSSNSSSSSESSSESELEHER---SRRRKHKRRPKVKRSKKRR 239
Query: 191 QAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPRERSPA 250
+ A ++ K G S+ + +E SA R V + P E P
Sbjct: 240 KEASSSEEPRNKHAMNPKGHSERSDTNEKRSV-------DSSAKREKPV--VRPEEIPPV 290
Query: 251 LKSPLQSVVVRRRSPRPSPVPKPSPPLSS---TSQMGSTLPSGAGYQS-GTHQGQFDHGS 306
P ++RR P + P+P P + + Q S SG + GT + S
Sbjct: 291 ---PENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRS 347
Query: 307 GSLSPSKKSPVGKSPP------------------------------------------ST 324
S S S ++PP S
Sbjct: 348 RSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSR 407
Query: 325 GSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLG 384
+Y + S A + KR E++ K K+QK K+ K++ + +
Sbjct: 408 SWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQ-TKKRRILIPSDIE 466
Query: 385 DGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFH-------------KEEMD 431
K + D E+ R S + + D+ K D K
Sbjct: 467 SSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQ 526
Query: 432 DQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELE 491
+ ++ R S+ + SK ++K+ +++ K + + K KTE L
Sbjct: 527 SYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLR 586
Query: 492 ---------------EESFPERSKKED-RGKRSEGGHRGFVP------------------ 517
E+ P + R + G + + P
Sbjct: 587 ATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPI 646
Query: 518 EKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFD 577
+ + + K SS K SES +K + +SS S R + R S+
Sbjct: 647 QSTYSLANIKETGSSSSYHKREKNSESDQSTYSK---YSDRSSESSPRSRSRSSRSRSYS 703
Query: 578 EDLARPSGLLA--QERKLCRDLVHSNKKEQEF-----RSIFQHIQSAQSQRSPSELFAQH 630
R L + + HS K + S + I S +R+ L +
Sbjct: 704 RSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSG 763
Query: 631 IVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHG 690
V H K H SS TLH ++ K G ++ + K S E +D S
Sbjct: 764 KKNSVSHKK--HSSSSEKTLHSKYVK----GRDRSSCVRKYS-ESRSSLDYS-------- 808
Query: 691 LAHDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSR 750
D +S + A+ K K ++ + H +++ RG+ + S R+ HS+
Sbjct: 809 --SDSEQSSVQATQSAQEKEKQGQME--------RTHNKQEKNRGEEK-SKSERECPHSK 857
Query: 751 ERSAEKTEKTH--KGSK-KQKKHRRARDRSRSSS------SSSQSSHSYKAEEYTEETEE 801
+R+ ++ H GSK K+K + ++ S S+S +S SH +E E T +
Sbjct: 858 KRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSD 917
Query: 802 REESTTGFD-KSRLGTKDFVG---PSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSN 857
E + K + TK P + G ++ + G+ S + NN
Sbjct: 918 SESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKS----SKQRTSTSDSEGSCSNSENNRGK 973
Query: 858 NDFQKRNREEEWDPEYTPKSKK 879
K +E E+T K K+
Sbjct: 974 PQKHKHGSKENLKREHTKKVKE 995
Score = 61.2 bits (147), Expect = 4e-09
Identities = 129/573 (22%), Positives = 220/573 (38%), Gaps = 89/573 (15%)
Query: 2 SKTNKSKSGS--RSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHN 59
SK++K S SSR S+S S+S+S+ SRSR+ S+S SRS+SRS S + +
Sbjct: 501 SKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHS-RSRSKSRSSSKSGH 559
Query: 60 RERNHPRVYQNRDFRGHNRGYR----RPYYFRGRNRGFYPWGQYNRG----GYGNYRSNW 111
R+R + N+ + R + N P N S W
Sbjct: 560 RKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRW 619
Query: 112 QNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHS-----------------RNSDKSSSDRS 154
+ ++ + P R + K P ++S +NS+ S S
Sbjct: 620 KPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYS 679
Query: 155 RRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDT 214
+ S S SS SR SS+ +S + S+ S + + + + SQ +
Sbjct: 680 KYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCS 739
Query: 215 KASESSKPWPDATYGTGSASRASA-VSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKP 273
++S + D R+S + +S ++ S + + L S V+ R R S V K
Sbjct: 740 RSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRD-RSSCVRKY 798
Query: 274 SPPLS----STSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKS----PPSTG 325
S S S+ S++ + Q QGQ + ++ KS P S
Sbjct: 799 SESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKK 858
Query: 326 STY----------GSSQKEESAASGGAAYTKRYLEEQKTENGK-------DKEQKQTNTD 368
T GS K ++ A G ++ E T+N K DKE+ + +D
Sbjct: 859 RTLKENLSDHLRNGSKPKRKNYA-GSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSD 917
Query: 369 KEK------IKEK---GSFSDTGLGD--GKMKSDSFAPKT-DSEKPFRGSQSPKRYKLRD 416
E IK K S ++T L D G KS T DSE S++ + +
Sbjct: 918 SESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKH 977
Query: 417 DFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVY 476
K + K E + K+K KG+K+ + +K + +++ W+
Sbjct: 978 KHGSK--ENLKREHTKKVKEKLKGKKDKK--------------HKAPKRKQAFHWQ---- 1017
Query: 477 APPGKEKQRKTEELEEESFPERSKKEDRGKRSE 509
PP + + + EE++++ + SK++ + +E
Sbjct: 1018 -PPLEFGEEEEEEIDDKQVTQESKEKKVSENNE 1049
Score = 60.5 bits (145), Expect = 7e-09
Identities = 111/515 (21%), Positives = 189/515 (36%), Gaps = 102/515 (19%)
Query: 38 SRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWG 97
SR +R LS RSRS SY+ ++ GH++ R+ + + +G
Sbjct: 395 SRWDERSLSQRSRSWSYNGYYSD-------LSTARHSGHHKKRRKEKKVKHKKKG----- 442
Query: 98 QYNRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRS 157
+Q + R +++ R S S+S +R KSS DR R S
Sbjct: 443 ----------------KKQKHCRRHKQTKKRRILIPSDIESSKSSTRRM-KSSCDRERSS 485
Query: 158 SSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKAS 217
SS SS+H SSKR +K K S + ++ D+ ++ Q++S G+S+ AS
Sbjct: 486 RSSSLSSHH----SSKRDWSKSDK--DVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTAS 539
Query: 218 ES-----SKPWPDATYGTGSASRAS-----AVSELSPRERSPALKSPLQSVVVRRR---- 263
+S S+ ++ +G RAS S+LS E P PL++ + +
Sbjct: 540 KSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLS--ENKPVKTEPLRATMAQNENVVV 597
Query: 264 ---------------SPRPS---PVPKP-SPPLSSTSQMGSTLPSGAGYQSGTHQGQFDH 304
SP PS P KP P +M + QS
Sbjct: 598 QPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKE 657
Query: 305 GSGSLSPSKKSPVGKSPPSTGSTYG-----SSQKEESAASGGAAYTKRYLEEQKTENGKD 359
S S K+ +S ST S Y SS + S +S +Y++ Y + +
Sbjct: 658 TGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHS 717
Query: 360 KEQKQTN--------TDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKR 411
+ + ++ +D + S++ DG+ +++ R S
Sbjct: 718 RSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRR----------AKRRLRSSGKKNS 767
Query: 412 YKLRDDFEKKMADFHKEEMDDQDKDK-----AKGRKESEFDDEPKFMSKVIGANKNQEEE 466
+ H + + +D+ ++ R ++ + + S V QE+E
Sbjct: 768 VSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSE-QSSVQATQSAQEKE 826
Query: 467 KSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKK 501
K G+ E +EK R E+ + E SKK
Sbjct: 827 KQGQME---RTHNKQEKNRGEEKSKSERECPHSKK 858
Score = 58.5 bits (140), Expect = 3e-08
Identities = 104/523 (19%), Positives = 195/523 (37%), Gaps = 69/523 (13%)
Query: 3 KTNKSKSGSRSSRSRSASRSRSR------SFSKSRSRSRSLSRSRKRRLSSRSRSRSYSP 56
K K G + R +++ R S+S +R + S R SSRS S S
Sbjct: 435 KVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLS--- 491
Query: 57 AHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQ 116
+H+ + RD+ ++ + R+ +YRS +++ Q
Sbjct: 492 SHHSSK--------RDWSKSDKDVQSSLTHSSRD---------------SYRS--KSHSQ 526
Query: 117 AYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKS 176
+YS RG SRSR+ + S RSRS SR+S KS + S +++S S + K +
Sbjct: 527 SYS--RGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEP 584
Query: 177 AKEKKSSSKDSRPSQAAGDN-----QGDEAKEQTFSGGTS---------QDTKASESSKP 222
+ + +++ +N D + G Q+ KA +
Sbjct: 585 LRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLL 644
Query: 223 WPDATYGTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQ 282
+TY + + S RE++ S + S R S S SS S+
Sbjct: 645 PIQSTYSLANIKETGSSSSYHKREKN----SESDQSTYSKYSDRSSESSPRSRSRSSRSR 700
Query: 283 MGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGA 342
S + + + +H S S SPS +S ++ S S S S +S
Sbjct: 701 SYSRSYTRSRSLASSH-------SRSRSPSSRSH-SRNKYSDHSQCSRSSSYTSISSDDG 752
Query: 343 AYTKRYLEEQKTENGKDKEQKQTNTDKEKIKE--KGSFSDTGLGDGKMKSDSFAPKTDSE 400
KR L +N ++ ++++K + KG + + S +DSE
Sbjct: 753 RRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSE 812
Query: 401 K-PFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGA 459
+ + +QS + + + E+ H ++ ++ ++K+K +E + +
Sbjct: 813 QSSVQATQSAQEKEKQGQMERT----HNKQEKNRGEEKSKSERECPHSKKRTLKENLSDH 868
Query: 460 NKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKE 502
+N + K + G + ++ T+ + +S P K+E
Sbjct: 869 LRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEE 911
Score = 55.5 bits (132), Expect = 2e-07
Identities = 90/406 (22%), Positives = 146/406 (35%), Gaps = 39/406 (9%)
Query: 414 LRDDFEKKMAD-FHKEEMDDQDKDKAKGRKESEFDDEP--------KFMSKVIGANKNQE 464
++D FEKK H E D + SE + E K KV + K ++
Sbjct: 181 IKDVFEKKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRK 240
Query: 465 EEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVT 524
E S + +A K +++ E+ S +K+E R E VPE F +
Sbjct: 241 EASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPE--EIPPVPENRFLLR 298
Query: 525 AYKAVQEKSSSPPPRK------TSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDE 578
V ++ P P+ S+ + + G G+ + + +S D+
Sbjct: 299 RDMPVV--TAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDD 356
Query: 579 DLAR-PSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHH 637
D + P + ++L S +K + + S +RS S+ +
Sbjct: 357 DSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYS 416
Query: 638 --VKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHR-----RIDISPSTFRKHG 690
H G E+ K+ K+G +Q+ + K + R I+ S S+ R+
Sbjct: 417 DLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMK 476
Query: 691 LAHDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSR 750
+ D +S R + K D D++ H RD R KS SR SS SR
Sbjct: 477 SSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSR 536
Query: 751 ERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYT 796
S K H R+R +SRSSS S + K+ T
Sbjct: 537 TAS------------KSSSHSRSRSKSRSSSKSGHRKRASKSPRKT 570
Score = 48.5 bits (114), Expect = 3e-05
Identities = 41/150 (27%), Positives = 64/150 (42%), Gaps = 17/150 (11%)
Query: 116 QAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSD--RSRRSSSSRSSSNHSRVESSK 173
Q+ SP R RS+S + R S SHSR+ +SS+ RSR S SRS +SR +
Sbjct: 1310 QSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRS 1369
Query: 174 RKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDA------- 226
R S+ S + S S++ + ++ ++++ + S S D+
Sbjct: 1370 RSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSY 1429
Query: 227 --------TYGTGSASRASAVSELSPRERS 248
+YG+ S S S SP E S
Sbjct: 1430 NRRSRSCRSYGSDSESDRSYSHHRSPSESS 1459
Score = 44.7 bits (104), Expect = 4e-04
Identities = 154/743 (20%), Positives = 258/743 (34%), Gaps = 144/743 (19%)
Query: 116 QAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSS-----SSRSSSNHSRVE 170
+AY P G S+ K P SR ++S S RSR S S S++ HS
Sbjct: 373 RAYRPPSGEKWSKGDKLSDPCS-----SRWDERSLSQRSRSWSYNGYYSDLSTARHS--- 424
Query: 171 SSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGT 230
+K KEKK K Q K + D ++S+SS ++
Sbjct: 425 GHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRIL---IPSDIESSKSSTRRMKSSCDR 481
Query: 231 GSASRASAVSE--LSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLP 288
+SR+S++S S R+ S + K S+ T
Sbjct: 482 ERSSRSSSLSSHHSSKRDWSKSDKDVQSSL---------------------------THS 514
Query: 289 SGAGYQSGTHQGQFDHGSG-SLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKR 347
S Y+S +H + GS S + SK S +S + S+ S ++ AS T
Sbjct: 515 SRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKR--ASKSPRKTAS 572
Query: 348 YLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQ 407
L E K K + + T E + + ++ + P +DS P R
Sbjct: 573 QLSENKPV--KTEPLRATMAQNENVVVQPVVAE---------NIPVIPLSDSPPPSRWKP 621
Query: 408 SPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEK 467
K +K + ++M + Q KE+ ++ + EK
Sbjct: 622 GQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETG------------SSSSYHKREK 669
Query: 468 SGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYK 527
+ + + Y+ K + ES P + R RS R + R +
Sbjct: 670 NSESDQSTYS--------KYSDRSSESSP---RSRSRSSRSRSYSRSYT-----RSRSLA 713
Query: 528 AVQEKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSIT----REAQVNVRMDSFDEDLARP 583
+ +S SP R S SR+K S SI+ R A+ +R ++
Sbjct: 714 SSHSRSRSPSSR--SHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHK 771
Query: 584 SGLLAQERKL------CRDLVHSNKKEQEFRSIFQHI-----QSAQSQRSPSELFAQHIV 632
+ E+ L RD +K E RS + S Q+ +S E Q +
Sbjct: 772 KHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQM 831
Query: 633 TIVHHVKEHHFG------------SSGMTLHERFTKYLKRGTE---QEAAKNKKSPEIHR 677
H+ +E + G S TL E + +L+ G++ + A +K E +
Sbjct: 832 ERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNS 891
Query: 678 RIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERD------ 731
D++ K+ S +E G +A + + ++ + ++ K
Sbjct: 892 ERDVT-----KNSKNDSHPSSDKEEG-EATSDSESEVSEIHIKVKPTTKSSTNTSLPDDN 945
Query: 732 --LKRGKSRESV-DSRDSSHSRERSAEKTEKTHKGSKK----------QKKHRRARDRSR 778
K K R S DS S + E + K +K GSK+ ++K + +D+
Sbjct: 946 GAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKH 1005
Query: 779 SSSSSSQSSHSYKAEEYTEETEE 801
+ Q+ H E+ EE EE
Sbjct: 1006 KAPKRKQAFHWQPPLEFGEEEEE 1028
Score = 42.7 bits (99), Expect = 0.002
Identities = 134/698 (19%), Positives = 237/698 (33%), Gaps = 113/698 (16%)
Query: 313 KKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKI 372
+K P + S SS + S + ++R +++ + + K++++ + E+
Sbjct: 189 RKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEP 248
Query: 373 KEKGSFSDTGLGDG-----KMKSDSFAPKTDSEKPF-RGSQSP----KRYKLRDDF---- 418
+ K + + G + K DS A + EKP R + P R+ LR D
Sbjct: 249 RNKHAMNPKGHSERSDTNEKRSVDSSAKR---EKPVVRPEEIPPVPENRFLLRRDMPVVT 305
Query: 419 ---EKKMADFHKEEMDDQDK-----DKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGK 470
E K+ D D + K KGR + P+ S ++ + E
Sbjct: 306 AEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRS-CSESDDDDSSETPPH 364
Query: 471 WEGLV-----YAPPGKEKQRKTEEL--------EEESFPERSKKEDRG--------KRSE 509
W+ + Y PP EK K ++L +E S +RS+ R
Sbjct: 365 WKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHS 424
Query: 510 GGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQV 569
G H+ EK + +K +K K ++ R ++ D + KSS TR +
Sbjct: 425 GHHKKRRKEKKVK---HKKKGKKQKHCRRHKQTKKR-RILIPSDIESSKSS---TRRMK- 476
Query: 570 NVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEF-----RSIFQHIQSAQSQRSPS 624
S D + + S L+ RD S+K Q R ++ +QS S
Sbjct: 477 ----SSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGS 532
Query: 625 ELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKK------------- 671
+ H SS + H + R T + ++NK
Sbjct: 533 SRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQN 592
Query: 672 -----SPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKK 726
P + I + P + + P +P Y+ + K L + +
Sbjct: 593 ENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHL---LPIQST 649
Query: 727 HKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQS 786
+ ++K S S H RE+++E + T+ + R RSRSS S S
Sbjct: 650 YSLANIKE------TGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSY- 702
Query: 787 SHSYKAEEYTEETEEREESTTGFDKSRLGTKD---------FVGPSERGGGRARGTFQFR 837
S SY + R S + SR D + S G RA+ +
Sbjct: 703 SRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSS 762
Query: 838 ARGRGWGRGNYSGNNNNNSNNDFQK-RNR--------EEEWDPEYTPKSKKYYLHDDREG 888
+ +S ++ ++ + K R+R E +Y+ S++ + +
Sbjct: 763 GKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSA 822
Query: 889 EGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDK 926
+ +K R + RG KS + + H K
Sbjct: 823 QEKEKQGQMERTHNKQEKNRGE---EKSKSERECPHSK 857
Score = 37.4 bits (85), Expect = 0.067
Identities = 26/103 (25%), Positives = 44/103 (42%), Gaps = 3/103 (2%)
Query: 722 ERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSS 781
++RKK + S S S SS S + HK K K+ ++ R + SSS
Sbjct: 187 KKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRR-KEASSS 245
Query: 782 SSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSE 824
++ H+ + ++E ++ E+ + D S K V P E
Sbjct: 246 EEPRNKHAMNPKGHSERSDTNEKRSV--DSSAKREKPVVRPEE 286
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 83.2 bits (204), Expect = 1e-15
Identities = 73/243 (30%), Positives = 108/243 (44%), Gaps = 18/243 (7%)
Query: 5 NKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNH 64
+K + R SRSRS SR R S RSRS SR RR S+SRSR S + R R+H
Sbjct: 240 DKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSR---RRSHSKSRSRRRSKSPRRRRSH 296
Query: 65 PRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGR 124
R + R R ++ + + + R P Y+ S + R++ S R
Sbjct: 297 SR-ERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSP 355
Query: 125 SRSRSPKR---RSPSPRSRSHSRNSDK----SSSDRSRRSSSSRSSSNHSRVESSKRKSA 177
+ RSPKR RSPSPR + DK S +R R +S + S + + K +S
Sbjct: 356 KKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESD 415
Query: 178 KEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRAS 237
K+ K ++D + D++ ++ +E+ S TK K GTG + R S
Sbjct: 416 KDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEK-------GTGDSLRES 468
Query: 238 AVS 240
V+
Sbjct: 469 KVN 471
Score = 56.6 bits (135), Expect = 1e-07
Identities = 76/315 (24%), Positives = 122/315 (38%), Gaps = 78/315 (24%)
Query: 121 RRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEK 180
R RSRSRS +RR+PS SR+ RSRR S S+S S + KS + +
Sbjct: 247 RHSRSRSRSRRRRTPSSSRHRRSRS-------RSRRRSHSKSRSRR------RSKSPRRR 293
Query: 181 KSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVS 240
+S S++ + D+ KE ++ K S++ P +Y T SR+++
Sbjct: 294 RSHSRERGRRSRSTSKTRDKKKE-------DKEKKRSKT----PPKSYSTARRSRSASRE 342
Query: 241 ELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQG 300
R RS RSP+ KP P S+
Sbjct: 343 RRRRRSRSGT------------RSPK-----KPRSPKRKLSR------------------ 367
Query: 301 QFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDK 360
SPS + + ++E S + + K E+K+E+ KD
Sbjct: 368 ---------SPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDV 418
Query: 361 EQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGS-QSPKRYKLRDDFE 419
+Q + D+E E+G S+ + K ++ +PKT +G+ S + K+ D
Sbjct: 419 KQVTRDYDEE---EQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGD-- 473
Query: 420 KKMADFHKEEMDDQD 434
D H+E+MD D
Sbjct: 474 ----DHHEEDMDMSD 484
Score = 45.8 bits (107), Expect = 2e-04
Identities = 40/183 (21%), Positives = 74/183 (40%), Gaps = 3/183 (1%)
Query: 716 DLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARD 775
D + + R + + R +R S R S SR RS K+ + +++ +R+
Sbjct: 240 DKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRE 299
Query: 776 RSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQ 835
R R S S+S++ K ++ + ++ +S + +SR +++ R G R +
Sbjct: 300 RGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSG--TRSPKK 357
Query: 836 FRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEG-SDKW 894
R+ R R + D K +E + + K K DRE + SDK
Sbjct: 358 PRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKD 417
Query: 895 VSR 897
V +
Sbjct: 418 VKQ 420
Score = 45.4 bits (106), Expect = 2e-04
Identities = 56/235 (23%), Positives = 93/235 (39%), Gaps = 27/235 (11%)
Query: 651 HERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKS-PREPGY----- 704
H R +R ++++++S RR S S R+ + +S RE G
Sbjct: 248 HSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRST 307
Query: 705 -KAEGKYKDDPVDLR-------LDIERRKKHKERDLKRGKSRESVDS--RDSSHSRERSA 754
K K K+D R RR + R+ +R +SR S + S R+ S
Sbjct: 308 SKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSR 367
Query: 755 EKTEKTHKGSKKQKKHR-RARD-RSRSSSSSSQSSHSYKAEEYTEE--------TEEREE 804
+ + HK KK+ K + R+RD R RS+S +S K E E T + +E
Sbjct: 368 SPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDE 427
Query: 805 STTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNND 859
G+D S K+ P E G + + + G +G++++ + D
Sbjct: 428 EEQGYD-SEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDMD 481
Score = 40.8 bits (94), Expect = 0.006
Identities = 50/242 (20%), Positives = 88/242 (36%), Gaps = 14/242 (5%)
Query: 719 LDIERRKKHKERDLKRGKSRESV-------DSRDSS--HSRERSAEKTEKTHKGSKKQKK 769
L + K E +KR + +S+ D ++ HSR RS + +T S+
Sbjct: 210 LKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSR---- 265
Query: 770 HRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGR 829
HRR+R RSR S S S + RE S+ K ++
Sbjct: 266 HRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKT 325
Query: 830 ARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGE 889
++ R R R + + + + + R+ + + +P+ K D++ E
Sbjct: 326 PPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKE 385
Query: 890 GSDKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREEKDN 949
S R + + + + RKS S K + E + +S E +EEK
Sbjct: 386 RSRDERERSTSKKKKSKDKEKDRERKSE-SDKDVKQVTRDYDEEEQGYDSEKEKKEEKKP 444
Query: 950 IQ 951
I+
Sbjct: 445 IE 446
Score = 33.5 bits (75), Expect = 0.97
Identities = 39/199 (19%), Positives = 78/199 (39%), Gaps = 27/199 (13%)
Query: 308 SLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNT 367
S S S++ KS S ++ S G + + ++K E+ K+K++ +T
Sbjct: 269 SRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKED-KEKKRSKTPP 327
Query: 368 DKEKIKEKGSFSDTGLGDGKMKSDSFAPKT--DSEKPFRGSQSPKRYKLRDDFEKKMADF 425
+ + + +S + +PK ++ S SP+R+K
Sbjct: 328 KSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHK------------ 375
Query: 426 HKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQR 485
KE+ D+DK++++ +E + K K + E +K K+ R
Sbjct: 376 -KEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKD-----------VKQVTR 423
Query: 486 KTEELEEESFPERSKKEDR 504
+E E+ E+ KKE++
Sbjct: 424 DYDEEEQGYDSEKEKKEEK 442
Score = 32.7 bits (73), Expect = 1.7
Identities = 46/252 (18%), Positives = 92/252 (36%), Gaps = 21/252 (8%)
Query: 318 GKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGK---DKEQKQTNTDKEKIKE 374
G PS S S + EE+ KR E Q + DK++++ + + +
Sbjct: 204 GLVSPSLKSDTSSKEIEEAM--------KRVREAQSLISAAIEPDKKEEKRRHSRSRSRS 255
Query: 375 KGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQD 434
+ + + + +S S + R S+SP+R + + + + D +
Sbjct: 256 RRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKK 315
Query: 435 KDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEES 494
+DK K R ++ PK S + E + + +P K+ + +L
Sbjct: 316 EDKEKKRSKT----PPKSYSTARRSRSASRERRRRRSRSGTRSP--KKPRSPKRKLSRSP 369
Query: 495 FPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDF 554
P R KKE + + + R ++ R T+ K + RK+ +D D+
Sbjct: 370 SPRRHKKEKKKDKDKERSR----DERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDY 425
Query: 555 PTGKSSFSITRE 566
+ + +E
Sbjct: 426 DEEEQGYDSEKE 437
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 82.4 bits (202), Expect = 2e-15
Identities = 117/437 (26%), Positives = 179/437 (40%), Gaps = 74/437 (16%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRS-------- 53
SK+++ KS R+S SRS +R RS RS++RS SRSR+RR SSRSRS+S
Sbjct: 1829 SKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSK 1888
Query: 54 ----YSPAH---NRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGN 106
SP H +RER R +RD R R R R+R P + G
Sbjct: 1889 EKRKRSPKHRSKSRERKRKR-SSSRDNRKTVRARSRTP--SRRSRSHTPSRRRRSRSVGR 1945
Query: 107 YRS-NWQNYRQAYSP-RRGRS---RSRSPKRRS--PSPRSRSHSRNSDKSSSDRSRRSSS 159
RS + R++ +P RR R+ RSR+P RRS PS RSR+ SR S S R RS
Sbjct: 1946 RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVV 2005
Query: 160 SRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQT-----------FSG 208
R S + S V + ++ ++ S R ++ +G K T +
Sbjct: 2006 RRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQLLEIAKAN 2065
Query: 209 GTSQDTKAS----ESSKPWPDATYGTGSASRA--SAVSELSPRERSPALKSPLQSVVVRR 262
+ KA + KP P T A ++ + + EL+ + + A V+V +
Sbjct: 2066 AAAMCAKAGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKEDDDVIVNK 2125
Query: 263 ------------------RSPRPSPV--------PKPSPPLSSTSQMGSTLPSGAGYQSG 296
+ P P+ KP+PP S + + P +G Q
Sbjct: 2126 PHVSDEEEEEPPFYHHPFKLSEPKPIFFNLNIAAAKPTPPKSQVT-LTKEFPVSSGSQH- 2183
Query: 297 THQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTEN 356
+ + D G P +K+ G+ + + S+ E A + +++ +EN
Sbjct: 2184 -RKKEADSVYGEWVPVEKN--GEENKDDDNVFSSNLPSEPVDISTAMSERALAQKRLSEN 2240
Query: 357 GKDKE-QKQTNTDKEKI 372
D E N +E+I
Sbjct: 2241 AFDLEAMSMLNRAQERI 2257
Score = 50.8 bits (120), Expect = 6e-06
Identities = 51/170 (30%), Positives = 72/170 (42%), Gaps = 6/170 (3%)
Query: 121 RRGRSRSRSPKRRSPSPRSRSHSR-NSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKE 179
R RS+S K R + SRS +R S KS S RS+ + SRS S R S R ++
Sbjct: 1825 RSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQ--TRSRSRSRRRRRSSRSRSKSRG 1882
Query: 180 KKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAV 239
++S SK+ R ++ E K + S ++ T + S P + T S R
Sbjct: 1883 RRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRR--- 1939
Query: 240 SELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPS 289
S R RS ++ +S RRS PS + S T S PS
Sbjct: 1940 SRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPS 1989
Score = 43.9 bits (102), Expect = 7e-04
Identities = 39/163 (23%), Positives = 73/163 (44%), Gaps = 12/163 (7%)
Query: 392 SFAPKTDSEKPFRGSQSPKRYKLRDDFE--KKMADFHKEEMDDQDKDKAKGRKESEFDDE 449
S A S P R S+S K DD+E K+ D H++ ++++D KG KE + D
Sbjct: 1766 SAASPVVSSMPERASESSSEEK--DDYEIFVKVKDTHEKSKKNKNRD--KGEKEKKRDSS 1821
Query: 450 PKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSE 509
+ SK +++++ +++ + K K ++ + S R ++ R +
Sbjct: 1822 LRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRS-QTRSRSRSRRRRRSSRSRSKS 1880
Query: 510 GGHRGFVPEKNFRVTAYKA-----VQEKSSSPPPRKTSESRDK 547
G R EK R +++ +++SSS RKT +R +
Sbjct: 1881 RGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSR 1923
Score = 40.4 bits (93), Expect = 0.008
Identities = 49/251 (19%), Positives = 95/251 (37%), Gaps = 23/251 (9%)
Query: 615 QSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTE-QEAAKNKKSP 673
+S+ ++ E+F + VK+ H S ++ K KR + + +K KS
Sbjct: 1781 ESSSEEKDDYEIFVK--------VKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSS 1832
Query: 674 EIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLK 733
E R S S R +S + ++++ + + RR++ R
Sbjct: 1833 EHKSRKRTSESRSRAR------KRSSKSKSHRSQTRSRSR--------SRRRRRSSRSRS 1878
Query: 734 RGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAE 793
+ + R SV S + ++ E+ K S + + R RSR+ S S+S +
Sbjct: 1879 KSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRR 1938
Query: 794 EYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNN 853
R S + +SR ++ PS R +R + R R R + + +
Sbjct: 1939 RSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRR 1998
Query: 854 NNSNNDFQKRN 864
S + ++R+
Sbjct: 1999 RRSRSVVRRRS 2009
Score = 32.0 bits (71), Expect = 2.8
Identities = 33/110 (30%), Positives = 44/110 (40%), Gaps = 8/110 (7%)
Query: 719 LDIERRKKHKERDLKRG--KSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDR 776
LD E R K DLK G KSR D + K K HK KK+KK + +
Sbjct: 73 LDTELRYKP---DLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKY 129
Query: 777 SRSSSSSSQSSHSYKAEEYTEETEE--REESTTGFDKSRLGTKDFVGPSE 824
R S + S+ E++ + +S L T+ F GPSE
Sbjct: 130 KRQPEESESKTKSHDDGNIDLESDSFLKFDSEPSAVALELPTRAF-GPSE 178
Score = 31.2 bits (69), Expect = 4.8
Identities = 46/210 (21%), Positives = 76/210 (36%), Gaps = 31/210 (14%)
Query: 123 GRSRSRSPKRRSPSPRSRSHSRNSDK---------------SSSDRSRRSSSSRSSSNHS 167
GR RS + S P S S + +K S +++R + S
Sbjct: 1762 GRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSS 1821
Query: 168 RVESSKRKSAKEKKSSSK--DSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPD 225
SKR + E KS + +SR ++ + QT S S+ + S S+
Sbjct: 1822 LRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSR---- 1877
Query: 226 ATYGTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGS 285
S SR R+RSP +S + +R S R + + + + + S
Sbjct: 1878 ------SKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRS 1931
Query: 286 TLPSGAGYQSGTHQGQFDHGSGSLSPSKKS 315
PS + + S S+SPS++S
Sbjct: 1932 HTPSRRRRSRSVGRRR----SFSISPSRRS 1957
Score = 31.2 bits (69), Expect = 4.8
Identities = 45/200 (22%), Positives = 72/200 (36%), Gaps = 28/200 (14%)
Query: 740 SVDSRDSSHSRERSAE-----KTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEE 794
S+ R S S E + K + TH+ SKK ++R + + S +
Sbjct: 1774 SMPERASESSSEEKDDYEIFVKVKDTHEKSKKN------KNRDKGEKEKKRDSSLRSRSK 1827
Query: 795 YTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFR---ARGRGWGRGNYSGN 851
++ +E + T +SR + S R R+R + R +R R RG S +
Sbjct: 1828 RSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVS 1887
Query: 852 N-------NNNSNNDFQKRNREEEWDPEYTPK------SKKYYLHDDREGEGSDKWVSRG 898
+ S + +KR R D T + S++ H S + V R
Sbjct: 1888 KEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRS-RSVGRR 1946
Query: 899 RGRGAFPRGRGRFMFRKSST 918
R P R R R+S T
Sbjct: 1947 RSFSISPSRRSRTPSRRSRT 1966
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 81.6 bits (200), Expect = 3e-15
Identities = 162/801 (20%), Positives = 292/801 (36%), Gaps = 70/801 (8%)
Query: 119 SPR-RGRSRS--RSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSK-R 174
SPR +G S + RSP+R + R R ++ D + + R ++ SS+ R ESS+ R
Sbjct: 64 SPRGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKR---NTEESSSPVRKESSRGR 120
Query: 175 KSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSAS 234
KE +K+ P + + + ++ + +G + D S +
Sbjct: 121 HREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKI----QRE 176
Query: 235 RASAVSELSPRERSPALKSPLQSVVVRRR-SPRPSPVPKPSPPLSSTSQMGSTLPSGAGY 293
E + +K + VVR + SP PS P +S S+
Sbjct: 177 LMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRK 236
Query: 294 QSGTHQGQFDHGSGSLS--PSKKSPVGKSPPST---GSTYGSSQKEESAASGGAAYTKRY 348
S D S + KK P SPP G KE+ Y +
Sbjct: 237 TSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEK--------YKVKD 288
Query: 349 LEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPF-RGSQ 407
E+KT +GKD+ + +EK + S S G + S + + S R S
Sbjct: 289 RIEEKTRDGKDRG-RDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSP 347
Query: 408 SPKRYK---------LRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIG 458
SP+R + L + + + + + ++ R S ++ + +
Sbjct: 348 SPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTS 407
Query: 459 ANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPE 518
+ ++ E+ G ++R+ E+ + S R +E R R R
Sbjct: 408 QSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDR 467
Query: 519 KNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDE 578
+ R + + R T ESRD ++ T + RE + R +
Sbjct: 468 RELR-DSRDMRDSREMRDYSRDTKESRDPRDSRS---TRDAHDYRDREGRDTHRKEDTYP 523
Query: 579 DLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSEL-----FAQHIVT 633
+ +R G + R + N+ E RS ++ + +S+ EL
Sbjct: 524 EESRSYGRNHLREESSRTEIR-NESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQ 582
Query: 634 IVHHVKEHHFGSSGMTLH---------ERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPS 684
I H ++ S T ER + R + E ++ +R D PS
Sbjct: 583 IDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPS 642
Query: 685 TFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSR 744
+ +H +DE++ + + ++ VD R+D R ++ +ERD +R + RE R
Sbjct: 643 SPIRHQGRNDELER--------DERREERRVD-RVDDRRDERARERDRERERDRERERER 693
Query: 745 DSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREE 804
+ RER E+ + + +++++ + RDR R + E E+ ERE
Sbjct: 694 ERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERER 753
Query: 805 STTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQK-R 863
++ R ++ ER RAR + R R R W + ++ + ++ R
Sbjct: 754 EER--ERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDR 811
Query: 864 NREEEWDPEYTPKSKKYYLHD 884
N + D KSKK Y ++
Sbjct: 812 NPRDGHDER---KSKKRYRNE 829
Score = 71.6 bits (174), Expect = 3e-12
Identities = 149/780 (19%), Positives = 288/780 (36%), Gaps = 107/780 (13%)
Query: 115 RQAYSPRRGRSR---SRSPKRRSPSPRSRSHSRNSDKSSSDR--SRRSSSSRSSSNHSRV 169
++ SP RS+ S S ++ S SP+ +S ++S S DR S SS +S+
Sbjct: 194 KKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKT 253
Query: 170 ESSKRKSA-------------------KEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGT 210
SK+K KEK G ++G + + Q
Sbjct: 254 NQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDK 313
Query: 211 SQDTKASESSKPWPDATYGTGSASRASAVSELSPRER-----SPALKSPLQSVVVRRRSP 265
+ T + + + + S+ S++ SP R SP+ + L + R SP
Sbjct: 314 PRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASP 373
Query: 266 RP-----SPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKS 320
P SP K SPP + +G+ DH S S ++ +
Sbjct: 374 YPSHSLSSPQRKQSPPRHRSPM--------------REKGRHDHERTSQSHDRRHERRED 419
Query: 321 PPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSD 380
S +EE + ++ + ++++ +G+D+ + D+ ++++ D
Sbjct: 420 TRGKRDREKDS-REEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRD 478
Query: 381 TGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKG 440
+ + ++ T + R S+S + D +++ D H++E ++ ++ G
Sbjct: 479 S------REMRDYSRDTKESRDPRDSRSTR--DAHDYRDREGRDTHRKEDTYPEESRSYG 530
Query: 441 RKESEFDDEPKFMSKVIGANKNQ-----EEEKSGKWEGLVYAPPGKEKQRKTEELEEESF 495
R E +++ ++N+ ++ G+ G V P K R + + +S
Sbjct: 531 RNHLR---EESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEK-GSRGSRGSQIDSH 586
Query: 496 PERSKKEDRGK-RSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDF 554
S D + RS R PE++ R A + E+ R+ + RD+ +
Sbjct: 587 SSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIR 646
Query: 555 PTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHI 614
G++ E + R+D D+ R ++R+ RD ++E+E +
Sbjct: 647 HQGRNDELERDERREERRVDRVDD--RRDERARERDRERERDRERERERERERDREREKE 704
Query: 615 QSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPE 674
+ + +R+ + ++ ER R E+E + ++ E
Sbjct: 705 RELERERAREREREREKERDRERDRDRDHDRERERERER-----DREKEREREREERERE 759
Query: 675 IHRRIDISPSTFRKHGLAHDEMKS-PREPGYKAEGKYKDD----PVDLRLDIERRKKHKE 729
R + R+ A + K R+ ++ + K +DD ++R D R H E
Sbjct: 760 RERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDE 819
Query: 730 R-DLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRAR-----DRSRSSSSS 783
R KR ++ S R S R + ++ + G K +KHR SRS S S
Sbjct: 820 RKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPS 879
Query: 784 -------------------SQSSHSYKAEEYTEE---TEEREESTTGFDKSRLGTKDFVG 821
+SS Y+ +E E+ +++ E T + SR+ +D +G
Sbjct: 880 HLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIG 939
Score = 63.9 bits (154), Expect = 7e-10
Identities = 160/830 (19%), Positives = 306/830 (36%), Gaps = 110/830 (13%)
Query: 4 TNKSKSGSRSSR-SRSASRSRSRSFSKSRSRSRSLSRSRK----RRLSSRSRSRSYSPAH 58
++ S+SGS R S S R R+ S S R+ + L RS LSS R +S
Sbjct: 333 SSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHR 392
Query: 59 NRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAY 118
+ R R R + H+R + R RG+ + Y +S+ +++R
Sbjct: 393 SPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREERE--YEQDQSSSRDHRDDR 450
Query: 119 SPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAK 178
PR GR R R + R R R+ SR SR ++SR R
Sbjct: 451 EPRDGRDR-----RDARDTRDRRELRD--------SRDMRDSREMRDYSRDTKESR---- 493
Query: 179 EKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASA 238
+DSR ++ A D + E + DT E + P +YG S+
Sbjct: 494 ----DPRDSRSTRDAHDYRDREGR----------DTHRKEDTYPEESRSYGRNHLREESS 539
Query: 239 VSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTH 298
+E+ R+ + +S +++ + R R +P+ S SQ+ S S + Y +
Sbjct: 540 RTEIRNESRNES-RSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSH-SSNSNYHD-SW 596
Query: 299 QGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGK 358
+ + + P + + S +G + ++ + + + E +
Sbjct: 597 ETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELER 656
Query: 359 DKEQKQTNTDK--EKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRD 416
D+ +++ D+ ++ E+ D + + + D E+ +R + R+
Sbjct: 657 DERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERE 716
Query: 417 DFEKKMADFHKEEMDDQDKDKAKGR---KESEFDDEPKFMSKVIGANKNQEEEKSGKWEG 473
+K D ++ D D+++ + R +E E + E + + + +E E+ + E
Sbjct: 717 REREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERER 776
Query: 474 LVYAPPGKEKQRKTEELEEESFPERSKKED--RGKRSEGGHRGFVPEKNFRVTAYKAVQE 531
+E+QR E+ ++ R K+E+ + GH +K +R
Sbjct: 777 ARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYR--------- 827
Query: 532 KSSSPPPRKTSESRDKLGAKGD-FPTGKS--------SFSITREAQVNVRMDSFDEDLAR 582
SP PR++ + R + D + +G S + + ++ ED R
Sbjct: 828 NEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTED--R 885
Query: 583 PSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELF------AQHIVTIVH 636
++RK R +EQE + + + S QR +E+ AQ I I H
Sbjct: 886 QGRWKEEDRKPERKESSRRYEEQELK---EKVSSVDKQREQTEILESSRMRAQDI--IGH 940
Query: 637 HVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEM 696
H E S H+ K K +++ K KK ++ G+ +
Sbjct: 941 HQSEDRETSD--RAHDENKK--KAKIQKKPIKKKKEDDV--------------GIERGNI 982
Query: 697 KSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEK 756
++ E G K + +K K + KR KS+ D D +++ ++
Sbjct: 983 ETTSEDGQVFSPK-------------KGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKR 1029
Query: 757 TEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREEST 806
+T + K++ ++ S + + ++ E+ +R E T
Sbjct: 1030 GPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVT 1079
Score = 62.0 bits (149), Expect = 3e-09
Identities = 176/877 (20%), Positives = 289/877 (32%), Gaps = 105/877 (11%)
Query: 6 KSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHP 65
K GSR S+ S S S S +RS R R +R ++R S ER H
Sbjct: 573 KGSRGSRGSQIDSHS-SNSNYHDSWETRSSYPERDRYPERDNRDQARDSS----FERRHG 627
Query: 66 RVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYR--SNWQNYRQAYSPRRG 123
RD R ++ P +GRN + R R + R + R
Sbjct: 628 E-RDRRDNRERDQRPSSPIRHQGRN------DELERDERREERRVDRVDDRRDERARERD 680
Query: 124 RSRSRSPKRRSPSPRSRSHSRNSDKS-----SSDRSRRSSSSRSSS-----NHSRVESSK 173
R R R +R R R R ++ + +R R R +H R +
Sbjct: 681 RERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERE 740
Query: 174 RKSAKEK-KSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGS 232
R+ +EK + ++ R + + + + +E+ +D K E + W D G
Sbjct: 741 RERDREKEREREREERERERERERERERERERERERARERD-KERERQRDWEDKDKGRDD 799
Query: 233 A--SRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSG 290
R + +PR+ KS +R SP P+ SP + P
Sbjct: 800 RREKREEIREDRNPRDGHDERKSK------KRYRNEGSPSPRQSP-----KRRREHSPDS 848
Query: 291 AGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLE 350
Y SG + + H S + SP KEE ++RY E
Sbjct: 849 DAYNSGDDKNE-KHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEE 907
Query: 351 EQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPK 410
++ E ++++ T+ + + G + + S +++K + + P
Sbjct: 908 QELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPI 967
Query: 411 RYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGK 470
+ K DD + + D Q KG+K+ + + K SK ++E + K
Sbjct: 968 KKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRK-KSKGDSDISDEEAAQQSK 1026
Query: 471 WEGLVYAPPGKEKQRKTEELEEES--FPERSKKEDRG----KRSEGGHRGFVPEKNFRVT 524
+ PP K+ E ++ + KKED + R V E T
Sbjct: 1027 KKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTAT 1086
Query: 525 AYKAVQEKSS------SPPPRKTSESRD--------KLGAKGDFPTGKSSFSITREAQVN 570
A S PPP T+ + A F T + S T N
Sbjct: 1087 ATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITIS-TSATPTN 1145
Query: 571 VRMDSF-DEDLARPSGLLAQERK-----LCRDLVHSNKKEQEFRSIFQHIQSAQSQ---- 620
++F +ED R E+ D H +Q+ S +S +S
Sbjct: 1146 TTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGR 1205
Query: 621 -RSPSELFAQHIVTIVHHVKEHHFGS-----SGMTLHERFTKYLKRGTEQEAAKNKKSPE 674
RSPS A H + G SG E+ G + K E
Sbjct: 1206 LRSPSNDSA-------HRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGE 1258
Query: 675 IHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKR 734
R R H +S R+ + G + D D + +R + +ER+ +R
Sbjct: 1259 PSRSTSSDRQDSRSHSSRRSSPESDRQV-HSRSGSF--DSRDRLQERDRYEHDRERERER 1315
Query: 735 GKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRS--------------- 779
+R+ RD+ R+ ++ + ++++ RR DR R
Sbjct: 1316 RDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDR 1375
Query: 780 --SSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRL 814
+ SSQ + E E ER+ +T D L
Sbjct: 1376 DRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLAL 1412
Score = 55.8 bits (133), Expect = 2e-07
Identities = 135/675 (20%), Positives = 235/675 (34%), Gaps = 88/675 (13%)
Query: 322 PSTGSTYGSSQKEESAASGGAAY--TKRYLEEQK------TENGKDKEQKQTNTDKEKIK 373
PSTGST +Q +G Y T R++ + N + ++ T +E++K
Sbjct: 32 PSTGST-AETQCRNWLKTGNCLYGNTCRFVHGPSPRGKGYSSNYRRSPERPTGDLRERMK 90
Query: 374 EKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFE--KKMADFHKEE-- 429
K DT K ++ +S P R S R++ ++D + K+ +EE
Sbjct: 91 NKRQDVDTE----PQKRNT----EESSSPVRKESSRGRHREKEDIKITKERTPESEEENV 142
Query: 430 -----MDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAP------ 478
DD D E E K K+ E+E K E ++
Sbjct: 143 EWETNRDDSDNGDINYDYVHELSLEMK-RQKIQRELMKLEQENMEKREEIIIKKEVSPEV 201
Query: 479 ------PGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPE-KNFRVTAYKAVQE 531
P ++ ++ + +S P+ S + +++ + + +N + K
Sbjct: 202 VRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGP 261
Query: 532 KSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVR---MDSFDEDLARPSGLLA 588
++ SPPP + K + TR+ + R D R +
Sbjct: 262 RTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAG 321
Query: 589 QERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGM 648
Q HS+ Q SI +H S + +R+PS + + + + +S
Sbjct: 322 QHHSPISSRHHSSSS-QSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRR------SASPY 374
Query: 649 TLHERFTKYLKRGTEQEAAK-NKKSPEIHRRIDISPSTFRKHGLAHDEM-KSPREPGYKA 706
H + K+ + + +K H R S S R+H D K RE +
Sbjct: 375 PSHSLSSPQRKQSPPRHRSPMREKGRHDHERT--SQSHDRRHERREDTRGKRDREKDSRE 432
Query: 707 EGKYKDDPV---DLRLDIERRKKHKERDLKRGKSR----------ESVDSRDSSHSRERS 753
E +Y+ D D R D E R RD + + R +S + RD S + S
Sbjct: 433 EREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKES 492
Query: 754 AEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSR 813
+ + + R RD R + + S SY EE+ E ++SR
Sbjct: 493 RDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESR 552
Query: 814 LGTKDFVGPSERGGGRARGTF-QFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPE 872
++ GR+RG + +G RG+ ++++NS N + W+
Sbjct: 553 SEIRN------DRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNS-------NYHDSWETR 599
Query: 873 YTPKSKKYYLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEG 932
+ + Y D + D R G R R R+ P + + G
Sbjct: 600 SSYPERDRYPERDNRDQARDSSFERRHGE------RDRRDNRERDQRPS-SPIRHQGRND 652
Query: 933 EIEDDESGTENREEK 947
E+E DE E R ++
Sbjct: 653 ELERDERREERRVDR 667
Score = 43.1 bits (100), Expect = 0.001
Identities = 49/223 (21%), Positives = 79/223 (35%), Gaps = 27/223 (12%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRE 61
++ + + R SR SR R +S+ SR SR R + R R H +E
Sbjct: 461 ARDTRDRRELRDSRDMRDSREM-RDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKE 519
Query: 62 RNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPR 121
+P + R + R + R R R S ++ + + R
Sbjct: 520 DTYPE-----ESRSYGRNHLREESSRTEIRN---------------ESRNESRSEIRNDR 559
Query: 122 RGRSRSRSPK------RRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRK 175
GRSR R P+ R S + SHS NS+ S +R S R R
Sbjct: 560 MGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARD 619
Query: 176 SAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASE 218
S+ E++ +D R ++ + Q + +D + E
Sbjct: 620 SSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREE 662
Score = 42.0 bits (97), Expect = 0.003
Identities = 63/231 (27%), Positives = 89/231 (38%), Gaps = 34/231 (14%)
Query: 727 HKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTH-KGSKKQKKHRRAR-DRSRSSSSSS 784
H+ D + G+ R HS R EKT+ G +K + + R + SRS+SS
Sbjct: 1215 HRSGDDQSGRKRVL-------HSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDR 1267
Query: 785 QSSHSYKAEEYTEETEEREESTTG-FD-KSRLGTKDFVGPSERGGGRARGTFQFRARGRG 842
Q S S+ + + E++ + S +G FD + RL +D R T R R
Sbjct: 1268 QDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDT-----RQRE 1322
Query: 843 WGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDKWVSRGRGRG 902
W R N + ++R RE E D K+ L +RE SD V R R
Sbjct: 1323 WDRDADKDWPRNRDRDRLRERERERERD-------KRRDLDRERERLISDS-VERDR--- 1371
Query: 903 AFPRGRGRFMFRKSSTSPKWAHDKFSGE-----EGEIEDDESGTENREEKD 948
R R R S K K GE E D + + R +KD
Sbjct: 1372 --DRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKD 1420
Score = 36.6 bits (83), Expect = 0.11
Identities = 65/251 (25%), Positives = 94/251 (37%), Gaps = 43/251 (17%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRE 61
S+ ++ K G SRS S+ R SRS S RS S + R S SR R
Sbjct: 1249 SRIDQLKRGE-PSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDR--------- 1298
Query: 62 RNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPR 121
Q RD H+R R R R +++R ++ N R
Sbjct: 1299 ------LQERDRYEHDRE-------RERERRDTRQREWDRDADKDWPRNRDRDR-----L 1340
Query: 122 RGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKK 181
R R R R +R R R SD DR R + S S++ES KR AK +
Sbjct: 1341 RERERERERDKRRDLDRERER-LISDSVERDRDRDRDRTFES---SQIESVKRCEAKLEG 1396
Query: 182 SSSKD----SRPSQAAGDNQGD------EAKEQTFSGGTSQDTKASESSKPWPDA-TYGT 230
+D SR S A + D + E+T ++ +A + DA + G+
Sbjct: 1397 EHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDESKLDDAHSLGS 1456
Query: 231 GSASRASAVSE 241
G+ +S+
Sbjct: 1457 GAGEGYEPISD 1467
Score = 36.2 bits (82), Expect = 0.15
Identities = 85/481 (17%), Positives = 178/481 (37%), Gaps = 85/481 (17%)
Query: 116 QAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRS---SSNHSRVESS 172
Q +SP++G+ + K+R +S+ S SD+ ++ +S++ R+ ++ VE
Sbjct: 990 QVFSPKKGQKKKSIEKKRK---KSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMC 1046
Query: 173 KRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPW--------P 224
K+ + S K+ D + E T + T+ T + P P
Sbjct: 1047 NGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPP 1106
Query: 225 DATY------GTGSASRASAVSELSP-----------------------------RERSP 249
AT T +A+ A+A + S R R
Sbjct: 1107 VATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVE 1166
Query: 250 ALKSPLQSVV-VRRRSP----RPSPVPKPSPPLSSTSQMGSTLPSGAGYQSG-------- 296
+++P ++ + R P R S + S TS + + + ++SG
Sbjct: 1167 KVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKR 1226
Query: 297 -THQGQFDH---GSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQ 352
H G D S ++ +KS + + S SS +++S + + +
Sbjct: 1227 VLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQV 1286
Query: 353 KTENG----KDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQS 408
+ +G +D+ Q++ + ++ +E+ DT + +D P+ R +
Sbjct: 1287 HSRSGSFDSRDRLQERDRYEHDRERER-ERRDTRQREWDRDADKDWPRNRDRDRLRERER 1345
Query: 409 PKRYKLRDDFEKKMADFHKEEMD-DQDKDKAKGRKESEFDDEPKFMSKVIGANKNQ---- 463
+ R D +++ + ++ D+D+D+ + + S+ + + +K+ G ++
Sbjct: 1346 ERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLEST 1405
Query: 464 -------EEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFV 516
++E+ K G V K +TE L E+ + SK +D G G+
Sbjct: 1406 SRDSLALDKERMDKDLGSVQGFEETNKSERTESL--EAGDDESKLDDAHSLGSGAGEGYE 1463
Query: 517 P 517
P
Sbjct: 1464 P 1464
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 81.3 bits (199), Expect = 4e-15
Identities = 80/226 (35%), Positives = 109/226 (48%), Gaps = 25/226 (11%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRS-------- 53
SK+++ KS R+S SRS +R RS RS++RS SRSR+RR SSRSRS+S
Sbjct: 1829 SKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSK 1888
Query: 54 ----YSPAH---NRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGN 106
SP H +RER R +RD R R R R+R P + G
Sbjct: 1889 EKRKRSPKHRSKSRERKRKR-SSSRDNRKTVRARSRTP--SRRSRSHTPSRRRRSRSVGR 1945
Query: 107 YRS-NWQNYRQAYSP-RRGRS---RSRSPKRRS--PSPRSRSHSRNSDKSSSDRSRRSSS 159
RS + R++ +P RR R+ RSR+P RRS PS RSR+ SR S S R RS
Sbjct: 1946 RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVV 2005
Query: 160 SRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQT 205
R S + S V + ++ ++ S R ++ +G K T
Sbjct: 2006 RRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLT 2051
Score = 50.8 bits (120), Expect = 6e-06
Identities = 51/170 (30%), Positives = 72/170 (42%), Gaps = 6/170 (3%)
Query: 121 RRGRSRSRSPKRRSPSPRSRSHSR-NSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKE 179
R RS+S K R + SRS +R S KS S RS+ + SRS S R S R ++
Sbjct: 1825 RSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQ--TRSRSRSRRRRRSSRSRSKSRG 1882
Query: 180 KKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAV 239
++S SK+ R ++ E K + S ++ T + S P + T S R
Sbjct: 1883 RRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRR--- 1939
Query: 240 SELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPS 289
S R RS ++ +S RRS PS + S T S PS
Sbjct: 1940 SRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPS 1989
Score = 43.9 bits (102), Expect = 7e-04
Identities = 39/163 (23%), Positives = 73/163 (44%), Gaps = 12/163 (7%)
Query: 392 SFAPKTDSEKPFRGSQSPKRYKLRDDFE--KKMADFHKEEMDDQDKDKAKGRKESEFDDE 449
S A S P R S+S K DD+E K+ D H++ ++++D KG KE + D
Sbjct: 1766 SAASPVVSSMPERASESSSEEK--DDYEIFVKVKDTHEKSKKNKNRD--KGEKEKKRDSS 1821
Query: 450 PKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSE 509
+ SK +++++ +++ + K K ++ + S R ++ R +
Sbjct: 1822 LRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRS-QTRSRSRSRRRRRSSRSRSKS 1880
Query: 510 GGHRGFVPEKNFRVTAYKA-----VQEKSSSPPPRKTSESRDK 547
G R EK R +++ +++SSS RKT +R +
Sbjct: 1881 RGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSR 1923
Score = 40.4 bits (93), Expect = 0.008
Identities = 49/251 (19%), Positives = 95/251 (37%), Gaps = 23/251 (9%)
Query: 615 QSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTE-QEAAKNKKSP 673
+S+ ++ E+F + VK+ H S ++ K KR + + +K KS
Sbjct: 1781 ESSSEEKDDYEIFVK--------VKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSS 1832
Query: 674 EIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLK 733
E R S S R +S + ++++ + + RR++ R
Sbjct: 1833 EHKSRKRTSESRSRAR------KRSSKSKSHRSQTRSRSR--------SRRRRRSSRSRS 1878
Query: 734 RGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAE 793
+ + R SV S + ++ E+ K S + + R RSR+ S S+S +
Sbjct: 1879 KSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRR 1938
Query: 794 EYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNN 853
R S + +SR ++ PS R +R + R R R + + +
Sbjct: 1939 RSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRR 1998
Query: 854 NNSNNDFQKRN 864
S + ++R+
Sbjct: 1999 RRSRSVVRRRS 2009
Score = 32.0 bits (71), Expect = 2.8
Identities = 33/110 (30%), Positives = 44/110 (40%), Gaps = 8/110 (7%)
Query: 719 LDIERRKKHKERDLKRG--KSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDR 776
LD E R K DLK G KSR D + K K HK KK+KK + +
Sbjct: 73 LDTELRYKP---DLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKY 129
Query: 777 SRSSSSSSQSSHSYKAEEYTEETEE--REESTTGFDKSRLGTKDFVGPSE 824
R S + S+ E++ + +S L T+ F GPSE
Sbjct: 130 KRQPEESESKTKSHDDGNIDLESDSFLKFDSEPSAVALELPTRAF-GPSE 178
Score = 31.2 bits (69), Expect = 4.8
Identities = 46/210 (21%), Positives = 76/210 (36%), Gaps = 31/210 (14%)
Query: 123 GRSRSRSPKRRSPSPRSRSHSRNSDK---------------SSSDRSRRSSSSRSSSNHS 167
GR RS + S P S S + +K S +++R + S
Sbjct: 1762 GRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSS 1821
Query: 168 RVESSKRKSAKEKKSSSK--DSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPD 225
SKR + E KS + +SR ++ + QT S S+ + S S+
Sbjct: 1822 LRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSR---- 1877
Query: 226 ATYGTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGS 285
S SR R+RSP +S + +R S R + + + + + S
Sbjct: 1878 ------SKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRS 1931
Query: 286 TLPSGAGYQSGTHQGQFDHGSGSLSPSKKS 315
PS + + S S+SPS++S
Sbjct: 1932 HTPSRRRRSRSVGRRR----SFSISPSRRS 1957
Score = 31.2 bits (69), Expect = 4.8
Identities = 45/200 (22%), Positives = 72/200 (36%), Gaps = 28/200 (14%)
Query: 740 SVDSRDSSHSRERSAE-----KTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEE 794
S+ R S S E + K + TH+ SKK ++R + + S +
Sbjct: 1774 SMPERASESSSEEKDDYEIFVKVKDTHEKSKKN------KNRDKGEKEKKRDSSLRSRSK 1827
Query: 795 YTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFR---ARGRGWGRGNYSGN 851
++ +E + T +SR + S R R+R + R +R R RG S +
Sbjct: 1828 RSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVS 1887
Query: 852 N-------NNNSNNDFQKRNREEEWDPEYTPK------SKKYYLHDDREGEGSDKWVSRG 898
+ S + +KR R D T + S++ H S + V R
Sbjct: 1888 KEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRS-RSVGRR 1946
Query: 899 RGRGAFPRGRGRFMFRKSST 918
R P R R R+S T
Sbjct: 1947 RSFSISPSRRSRTPSRRSRT 1966
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 79.7 bits (195), Expect = 1e-14
Identities = 65/188 (34%), Positives = 92/188 (48%), Gaps = 26/188 (13%)
Query: 6 KSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLS-SRSRSRSYSPAHNRERNH 64
+ K + RS S SRSRSRS +SRSRSR SRSR R +S SRSRSRS S +R R+
Sbjct: 180 EDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSK 239
Query: 65 PRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGR 124
R + ++ +P + +RG + + RS + Y R R
Sbjct: 240 GR-------KSRSKSKSKP--------------KSDRGSHSHSRSR---SKDEYEKSRSR 275
Query: 125 SRSRSPKRRSPSP-RSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSS 183
SRSRSPK +S+S SR+ +S+S S +RS S + +S+ +S KS
Sbjct: 276 SRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSR 335
Query: 184 SKDSRPSQ 191
S+ S+
Sbjct: 336 SRSRSSSR 343
Score = 53.1 bits (126), Expect = 1e-06
Identities = 46/152 (30%), Positives = 71/152 (46%), Gaps = 9/152 (5%)
Query: 113 NYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESS 172
++R++YS R RSRSR R SRS SR+ KS RS S S SR S
Sbjct: 186 SHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKS------RSRSRSRSKGRSRSRSK 239
Query: 173 KRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGS 232
RKS + KS K R S + ++ + E++ S S+ K E+ K + + S
Sbjct: 240 GRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPK--ENGKGDIKSKSRSRS 297
Query: 233 ASRASAVSELSPRERSPALKSPLQSVVVRRRS 264
SR+++ + P ++ ++ P + R RS
Sbjct: 298 QSRSNSPLPVPP-SKARSVSPPPKRATSRSRS 328
Score = 51.2 bits (121), Expect = 5e-06
Identities = 45/150 (30%), Positives = 69/150 (46%), Gaps = 9/150 (6%)
Query: 100 NRGGYGNYRSNWQNYRQAYSPRR--GRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRS 157
+R Y RS ++ R++ S R RSRSRS + RSRS R+ +S +SR
Sbjct: 187 HRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSK 246
Query: 158 SSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGD-EAKEQTFSGGTSQD--- 213
S S+ S+ S+ +S E + S SR + +GD ++K ++ S S
Sbjct: 247 SKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLP 306
Query: 214 ---TKASESSKPWPDATYGTGSASRASAVS 240
+KA S P AT + S SR+ + S
Sbjct: 307 VPPSKARSVSPPPKRATSRSRSRSRSKSRS 336
Score = 44.3 bits (103), Expect = 6e-04
Identities = 33/133 (24%), Positives = 55/133 (41%), Gaps = 6/133 (4%)
Query: 716 DLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARD 775
++RL ++ + R +SR R S SR S ++ K + + + R
Sbjct: 175 NIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRS 234
Query: 776 RSRSSSSSSQS-SHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTF 834
RSRS S+S S S + + R S ++KSR ++ P E G +G
Sbjct: 235 RSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRS-RSPKENG----KGDI 289
Query: 835 QFRARGRGWGRGN 847
+ ++R R R N
Sbjct: 290 KSKSRSRSQSRSN 302
Score = 40.0 bits (92), Expect = 0.010
Identities = 44/153 (28%), Positives = 59/153 (38%), Gaps = 11/153 (7%)
Query: 137 PRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDN 196
PR+ S S RSRR S SRS + S KS +S SK S++ G
Sbjct: 183 PRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRK 242
Query: 197 QGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPRERSPALKSPLQ 256
++K + S S S S D + S SR+ + E + +S Q
Sbjct: 243 SRSKSKSKPKSDRGSHSHSRSRSK----DEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQ 298
Query: 257 SVVVRRRSPRPSPVPK----PSPPLSSTSQMGS 285
S R SP P P K PP +TS+ S
Sbjct: 299 S---RSNSPLPVPPSKARSVSPPPKRATSRSRS 328
Score = 38.9 bits (89), Expect = 0.023
Identities = 40/140 (28%), Positives = 59/140 (42%), Gaps = 11/140 (7%)
Query: 147 DKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTF 206
DK + R S SRS S S +R ++ ++SS SR + +K ++
Sbjct: 181 DKPRTSHRRSYSGSRSRS-----RSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSR 235
Query: 207 SGGTSQDTKASESSKPWPDATYGTGSASRASAVSELS---PRERSPAL--KSPLQSVVVR 261
S + +++ SKP D + S SR+ E S R RSP K ++S R
Sbjct: 236 SRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKS-KSR 294
Query: 262 RRSPRPSPVPKPSPPLSSTS 281
RS S P P PP + S
Sbjct: 295 SRSQSRSNSPLPVPPSKARS 314
Score = 34.3 bits (77), Expect = 0.57
Identities = 32/111 (28%), Positives = 48/111 (43%), Gaps = 18/111 (16%)
Query: 723 RRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQ----------KKHRR 772
R K K R + KS+ D SHSR RS ++ EK+ S+ + K R
Sbjct: 237 RSKGRKSRS--KSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSR 294
Query: 773 ARDRSRSSS-----SSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKD 818
+R +SRS+S S S S + T + R S + +SR ++D
Sbjct: 295 SRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSR-SRSRSSSRD 344
Score = 33.1 bits (74), Expect = 1.3
Identities = 51/279 (18%), Positives = 98/279 (35%), Gaps = 25/279 (8%)
Query: 292 GYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEE 351
GY G+ G G S + S K P + Y + S+ K ++ +
Sbjct: 79 GYSYGSRSG-----GGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDL-KDFMRQ 132
Query: 352 QKTENGKDKEQKQTNTDKEKIKEKGSFSD----------TGLGDGKMKSDSFAPKTDSEK 401
D +++TN E + E S+SD T + ++ P+T +
Sbjct: 133 AGEVTYADAHKERTN---EGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRR 189
Query: 402 PFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANK 461
+ GS+S R + R + + + + + +++ R + K +K
Sbjct: 190 SYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRK---SRSK 246
Query: 462 NQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNF 521
++ + KS + K++ K+ P+ + K D +S + N
Sbjct: 247 SKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQS---RSNS 303
Query: 522 RVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTGKSS 560
+ + S PP R TS SR + +K + SS
Sbjct: 304 PLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSS 342
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 79.7 bits (195), Expect = 1e-14
Identities = 133/579 (22%), Positives = 197/579 (34%), Gaps = 127/579 (21%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRE 61
S SK ++R SRSRS+S S++RSRS S +R R+R RSRSRSYSP R
Sbjct: 260 SPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRH---RSRSRSYSP---RR 313
Query: 62 RNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPR 121
R PR RRP SPR
Sbjct: 314 RPSPR--------------RRP-----------------------------------SPR 324
Query: 122 RGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKE-K 180
R R+P RR P P SR S R RRSS+S S S+ S S R K+
Sbjct: 325 R-----RTPPRRMPPPPRHRRSR----SPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPP 375
Query: 181 KSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVS 240
K +S R ++ + + S + K S P + +R S VS
Sbjct: 376 KRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTP------QQSNRTRKSRVS 429
Query: 241 ELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQG 300
+SP S K +R SP P+P P+ S G + + Q
Sbjct: 430 -VSPGRTSG--KVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYR 486
Query: 301 QFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDK 360
+ + S S S S S + P K +G +R+ + K
Sbjct: 487 RQNQQSSSDSGSSSSSEDERP-----------KRSHVKNGEVGRRRRHSPSRSASPSPRK 535
Query: 361 EQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAP--------------KTDSEKPFRGS 406
QK+T+ + + S + + +S S AP +T S P R S
Sbjct: 536 RQKETSPRGRRRR-----SPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRS 590
Query: 407 QSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEE 466
SP+RY +++ + + R+ S + +S
Sbjct: 591 PSPRRYS--PPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVS------------ 636
Query: 467 KSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAY 526
++PP K++ + S + +K RS R P K +
Sbjct: 637 ---------HSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPR 687
Query: 527 KAVQEKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITR 565
+ SSSPPP + S + P+ + ++R
Sbjct: 688 PRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSR 726
Score = 68.9 bits (167), Expect = 2e-11
Identities = 105/458 (22%), Positives = 168/458 (36%), Gaps = 48/458 (10%)
Query: 109 SNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSR 168
S+ + ++ SPRR +SRS SP+RRS SP R R+ +S R++ S S + +
Sbjct: 161 SSREKRERSRSPRRRKSRSPSPRRRS-SPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEK 219
Query: 169 VESSKRKSAKEKKSSSKDSRPS----QAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWP 224
S K K+ S +++ + + E KE + S+ K E ++P
Sbjct: 220 TPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPS-PEKNSKKEKEKEKTRPRS 278
Query: 225 DATYGTGSASRASAVSELSPRER--------SPALK-SPLQSVVVRRRSPRPSPVPKPSP 275
+ + S +R+ + S PR R SP + SP + RRR+P P +P P
Sbjct: 279 RSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTP-PRRMPPPPR 337
Query: 276 PLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEE 335
S S + S A + S S S +SP K P T S +++
Sbjct: 338 HRRSRSPVRRRRRSSASLSGSS--------SSSSSSRSRSPPKKPPKRTSSPPRKTRRLS 389
Query: 336 SAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAP 395
+AS +R+ T + ++ G GK+
Sbjct: 390 PSAS---PPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTE 446
Query: 396 KTDSEKPFRGSQSPKRYKLRDDFEKK---------MADFHKEEMDDQDKDKAKGRKESEF 446
K +S P + P++ +L + E K + + +Q G S
Sbjct: 447 KRESPSP---APKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSE 503
Query: 447 DDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGK 506
D+ PK S V KN E + + A P K++K S R +
Sbjct: 504 DERPK-RSHV----KNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRR 558
Query: 507 RSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSES 544
RS P R T + ++ SPPPR+ S S
Sbjct: 559 RSPSP----APPPRRRRTPTPPPRRRTPSPPPRRRSPS 592
Score = 65.1 bits (157), Expect = 3e-10
Identities = 97/401 (24%), Positives = 148/401 (36%), Gaps = 45/401 (11%)
Query: 4 TNKSKSGSRSSRSRSASRSRSRSFSKSRS------RSRSLSRSRKRRLSSRSRSRSYSPA 57
T K +S S + + R S S + + R R + ++ SS S S S S
Sbjct: 445 TEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED 504
Query: 58 HNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQA 117
+R+H + + R H+ R R + P G+ R ++ A
Sbjct: 505 ERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPA 564
Query: 118 YSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSS-----RSSSNHSRVESS 172
PRR R+ + P+RR+PSP R S + + S RR S S R++S +
Sbjct: 565 PPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRR 624
Query: 173 KRKSAKEKKSSSKDSRPSQAAGD--NQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGT 230
S K+ S P Q + + + G+S E+ P P+ +
Sbjct: 625 ASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 684
Query: 231 GSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPS----------PVPK-------P 273
RA S P R A SP RR+SP PS P PK P
Sbjct: 685 SPRPRAPQTSSSPPPVRRGASSSPQ-----RRQSPSPSTRPIRRVSRTPEPKKIKKAASP 739
Query: 274 SPPL-----SSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTY 328
SP SS S GS P+ + Q S + SP+ KSP + S
Sbjct: 740 SPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPP 799
Query: 329 GSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDK 369
+S +E GG K+ +++ ++ K K+ K+ +K
Sbjct: 800 RNSDQE-----GGGKKKKKKKDKKHKKDKKHKKHKKHKKEK 835
Score = 64.7 bits (156), Expect = 4e-10
Identities = 94/375 (25%), Positives = 134/375 (35%), Gaps = 44/375 (11%)
Query: 11 SRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQN 70
++ S S S S S S RS ++ R+RR S SRS S SP ++ PR
Sbjct: 489 NQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRR-HSPSRSASPSPRKRQKETSPR---- 543
Query: 71 RDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRSRSP 130
G R P R R R P R R P R R+ S P
Sbjct: 544 ----GRRRRSPSPPPTR-RRRSPSPAPPPRRR------------RTPTPPPRRRTPSPPP 586
Query: 131 KRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPS 190
+RRSPSPR S S S +R ++S R +S K + S S +
Sbjct: 587 RRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRR--ASPSPPPKRRVSHSPPPKQR 644
Query: 191 QAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPRERSPA 250
+ + + G+S E+ P P+ + RA S P R A
Sbjct: 645 SSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGA 704
Query: 251 LKSPLQSVVVRRRSPRPS----------PVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQG 300
SP RR+SP PS P PK +S S S + SG+ +
Sbjct: 705 SSSP-----QRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPE- 758
Query: 301 QFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDK 360
+ P+ SPV PST + K+ + + + + +E + K K
Sbjct: 759 ----PAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKK 814
Query: 361 EQKQTNTDKEKIKEK 375
+ K+ DK+ K K
Sbjct: 815 KDKKHKKDKKHKKHK 829
Score = 36.2 bits (82), Expect = 0.15
Identities = 49/230 (21%), Positives = 80/230 (34%), Gaps = 14/230 (6%)
Query: 659 KRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSP--REPGYKAEGKYKDDPVD 716
K E K ++S RR SPS R+ E K R P ++ + + +
Sbjct: 156 KEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPE 215
Query: 717 LRLDI----ERRKKHKERDLKRGKSRESV----DSRDSSHSRERSAEKTEKTHKGSKKQK 768
+ E K KE ++ S + +E S EK K K +K +
Sbjct: 216 KKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTR 275
Query: 769 KHRRARDRSRSSSSSSQSSHSYKAEEYTEETE----EREESTTGFDKSRLGTKDFVGPSE 824
R+R +SRS + S SH+ + + R S R T P
Sbjct: 276 PRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPP 335
Query: 825 RGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYT 874
R+R + R R G+ S ++++ S + +K + P T
Sbjct: 336 PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKT 385
Score = 31.2 bits (69), Expect = 4.8
Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 13/97 (13%)
Query: 720 DIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKK---------- 769
+I++R+ +E+ K E D RD +E S EK E++ +++ +
Sbjct: 130 EIKQRQIEQEKLASMKKQDEDKDKRDKEE-KESSREKRERSRSPRRRKSRSPSPRRRSSP 188
Query: 770 --HRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREE 804
R R SRS ++S A E E+T E E
Sbjct: 189 VRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPE 225
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 79.3 bits (194), Expect = 2e-14
Identities = 107/494 (21%), Positives = 189/494 (38%), Gaps = 71/494 (14%)
Query: 112 QNYRQAYSPRRGRSRSRSPKRRSPSP-RSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVE 170
+N + +P ++++++P P P R+ N +SS S SSSS S +
Sbjct: 181 KNQKPKITPVTVKAQTKAP----PKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAA 236
Query: 171 SSKRKSAKEK--------KSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKP 222
++ +K+ +K K+++ +R S ++ D+ DE +EQ +S
Sbjct: 237 ATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPS 296
Query: 223 WPDATYGTGSASRASAVSELSPRERSPAL-----------KSPLQSVVVRRRSPRPSPVP 271
P G+ AV + P E S K P VV + + +P P
Sbjct: 297 APPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAK 356
Query: 272 KPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSS 331
K + S +S S+ A + G + S + + KSP K + G
Sbjct: 357 KAAESSSDSSDSDSSEDDEAPSKPA---GTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGG 413
Query: 332 QKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFS------DTGLGD 385
QK + + ++ EE+ + + ++K +K T K K K + S G D
Sbjct: 414 QKLLTRKADSSSS-----EEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRD 468
Query: 386 GKMKSDSFAPKTDSEKPFRGSQSPKRYKLR----------------DDFEKKMADFHKEE 429
SDS + + + EK + + K K+ + +D EE
Sbjct: 469 SSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEE 528
Query: 430 MDDQDKDKAKGRKESEFDDEPKFMSKVIG--ANKNQEEEKSGKWEGLVYAPPGKEKQRKT 487
+++ K K R ++ + ++ G A ++EEE+ K +V + G K+RK
Sbjct: 529 EEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQ 588
Query: 488 EELEEESFPERSKK------EDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKT 541
E +E+ ++KK KR +G R P ++ V+E+ R
Sbjct: 589 NEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSP--------FRRVREEEIEVDSRVA 640
Query: 542 SESRD-KLGAKGDF 554
S D K GA GD+
Sbjct: 641 DNSFDAKRGAAGDW 654
Score = 56.6 bits (135), Expect = 1e-07
Identities = 113/598 (18%), Positives = 210/598 (35%), Gaps = 53/598 (8%)
Query: 148 KSSSDRSRRSSSSRSSSNHSRVESSKRKSA------------KEKKSSSKDSRPSQAAGD 195
K + ++ S S SS V+ K A K +S+ S +++ D
Sbjct: 76 KKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDD 135
Query: 196 NQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPRERSPALKSPL 255
+ ++ K+Q G KA+++ P + S S +S+ E P+ + P +
Sbjct: 136 DDEEDQKKQPVQKGVKPQAKAAKAP---PKKAKSSDSDSDSSSEDE-PPKNQKPKITP-- 189
Query: 256 QSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKS 315
V V+ ++ P + +P +++ S+ S + S + + + + KK
Sbjct: 190 --VTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQ 247
Query: 316 PVGKSP--PSTGSTYGSSQKEESAASGGAAYTKR-------YLEEQKTENGKDKEQKQTN 366
V K+P +T T SS E+S++ K Y K+ T
Sbjct: 248 VVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQ 307
Query: 367 TDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFH 426
K+ ++++ + D +SDS ++ EK + + KK A+
Sbjct: 308 PPKKAVEKQQPVESSE--DSSDESDS---SSEEEKKPPTKAVVSKATTKPPPAKKAAE-- 360
Query: 427 KEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRK 486
D D D SE D+ P SK G KN + + + P KQ
Sbjct: 361 -SSSDSSDSDS------SEDDEAP---SKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPV 410
Query: 487 T--EELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSES 544
++L S +E+ E + V + TA A+ + P S
Sbjct: 411 GGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSS 470
Query: 545 RDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKE 604
D + + K+S S ++ V + A A+ S ++E
Sbjct: 471 SDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEE 530
Query: 605 QEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTEQ 664
++ + A S L AQ+ + +E + + + LK+ +
Sbjct: 531 EKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSK-SGSLKKRKQN 589
Query: 665 EAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSP----REPGYKAEGKYKDDPVDLR 718
EAAK ++P+ + +P+TF K SP RE + + + D+ D +
Sbjct: 590 EAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSPFRRVREEEIEVDSRVADNSFDAK 647
Score = 54.7 bits (130), Expect = 4e-07
Identities = 89/443 (20%), Positives = 157/443 (35%), Gaps = 33/443 (7%)
Query: 130 PKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVES----SKRKSAKEKKSSSK 185
P +R P ++ ++ S+ SSS+ S + +K A KK+ S
Sbjct: 108 PAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSS 167
Query: 186 DSRPSQAAGDNQGDEAKEQTFSGGTSQDTKA-SESSKPWPDATYG--TGSASRASAVSEL 242
DS ++ D K + TKA + ++ P G S+S +S+ S
Sbjct: 168 DSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSS 227
Query: 243 SPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPL---SSTSQMGSTLPSGAGYQSGTHQ 299
E A +P + V +++ +PV + P SS+ S
Sbjct: 228 DDSEEEKAAATP-KKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKP 286
Query: 300 GQFDHGSGSLSPSKKSPVGKSPPS---------TGSTYGSSQKEESAASGGAAYTKRYLE 350
G + +P K +G PP S S + + S+ TK +
Sbjct: 287 GPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVS 346
Query: 351 EQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPK 410
+ T+ K+ ++++D S SD+ D + K S KP ++SP
Sbjct: 347 KATTKPPPAKKAAESSSD-------SSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSP- 398
Query: 411 RYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGK 470
++ K +++ + D + +ES +E K K++ K + K+
Sbjct: 399 --AVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEK-TKKMVATTKPKATAKAAL 455
Query: 471 WEGLVYAPPG-KEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAV 529
AP G ++ ++ E E++ K K+ + G P K KA
Sbjct: 456 SLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAE 515
Query: 530 QEKSSSPPPRKTSESRDKLGAKG 552
SSS + E +KL KG
Sbjct: 516 SSNSSSSDD-SSEEEEEKLKGKG 537
Score = 33.9 bits (76), Expect = 0.75
Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 9/71 (12%)
Query: 737 SRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSS-----SQSSHSYK 791
SR+S DSS S E+ EKT K + K+K + A + S +S ++SS+S
Sbjct: 466 SRDSSSDSDSSSSE----EEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSS 521
Query: 792 AEEYTEETEER 802
+++ +EE EE+
Sbjct: 522 SDDSSEEEEEK 532
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 79.0 bits (193), Expect = 2e-14
Identities = 183/861 (21%), Positives = 305/861 (35%), Gaps = 106/861 (12%)
Query: 2 SKTNKSKSGSRSSRSRS---ASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAH 58
S +S+ GSR RS AS S S+ + + SR + SS ++RS SP
Sbjct: 324 SAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARS-SPGE 382
Query: 59 NRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNY---- 114
H Q+ D H+ R +RG +RG G+ S+ + +
Sbjct: 383 RHGSGHQ---QSADSSRHSATGRGQASSAVSDRG-------HRGSSGSQASDSEGHSENS 432
Query: 115 -------------RQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSR 161
RQ R RS RS S + + S+ R+ S+ R
Sbjct: 433 DTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGR 492
Query: 162 SSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSK 221
S+H + S R SA ++ + P + G QG ++ G S + +S+
Sbjct: 493 QGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQ 552
Query: 222 PWPDATY---GTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPV--PKPSPP 276
DA++ G+ SASR + E S + + S + S R S V + S P
Sbjct: 553 GRSDASHGQSGSRSASRQTRNEEQS-GDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGP 611
Query: 277 LSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEES 336
+S +Q GS++ + Q H + SGS S + + GS + S E+
Sbjct: 612 RTSRNQ-GSSVSQDSDSQG--HSEDSERWSGSASRNHHGS-AQEQSRDGSRHPRSHHEDR 667
Query: 337 AASGGAAYTKRYLEEQKTEN------GKDKEQKQTNT-----DKEKIKEKGSFSDTGLGD 385
A G +A + R + T+N EQ +++ + +++ S +G G
Sbjct: 668 AGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGH 727
Query: 386 GKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESE 445
G+ S A + + GSQ+ +D + + H + Q + R S
Sbjct: 728 GQASS---AVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSG 784
Query: 446 FDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEES----------- 494
+ + S + + +++ E S W G G + E+ + S
Sbjct: 785 -ERSRRSGSFLYQVSTHKQSESSHGWTG---PSTGVRQGSHHEQARDNSRHSASQDGQDT 840
Query: 495 ---FPERSKKEDRGKRSE---------GGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTS 542
P S++ +G E G H + + +S+S R
Sbjct: 841 IRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEE 900
Query: 543 ESRDKLGAKGDFPTGKSSFS-ITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSN 601
+SRD G SS + I+R +Q R ++Q+ HS
Sbjct: 901 QSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSD---SEGHSE 957
Query: 602 KKEQEFRSIFQ-HIQSAQSQ-RSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLK 659
E+ S + H SAQ Q R S H H T H + +
Sbjct: 958 DSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQ 1017
Query: 660 RGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSP-REPGY---------KAEGK 709
+ E A++ R S + R G+ + S R+ G+ +EG
Sbjct: 1018 AASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGH 1077
Query: 710 YKDDPVDL----RLDIERRKKHKE--RDLKRGKSRESVD--SRDSSHSRERSAEKTEKTH 761
++ D ++ H+E RD G+S S + S+H + SA +T
Sbjct: 1078 SEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTS 1137
Query: 762 KGSKKQKKHRRARDRSRSSSS 782
G ++ H +ARD SR S+S
Sbjct: 1138 TGRRQGSHHEQARDSSRHSAS 1158
Score = 77.0 bits (188), Expect = 8e-14
Identities = 177/873 (20%), Positives = 313/873 (35%), Gaps = 105/873 (12%)
Query: 2 SKTNKSKSGSRSSRSRSASRS-RSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNR 60
S +S+ GSR RS R+ S SR + + ++ S ++ S A R
Sbjct: 2270 SAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGER 2329
Query: 61 ERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSP 120
+H + Q+ D H+ R+ G +RG G+ S+ + + +
Sbjct: 2330 HGSHHQ--QSADSSRHSGIGHGQASSAVRDSG-------HRGSSGSQASDSEGHSEDSDT 2380
Query: 121 R-------------------RGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSR 161
+ RGRS RS + S + +H ++ +S+ R+ S+ R
Sbjct: 2381 QSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQS--ESAHGRTGTSTGGR 2438
Query: 162 SSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSK 221
S+H + S R S ++ + P ++G QG ++ G S + +S+
Sbjct: 2439 QGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQ 2498
Query: 222 PWPDATY---GTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLS 278
DA++ G+ SASR + E S + S S R S S V +
Sbjct: 2499 GRSDASHGHSGSRSASRQTRNDEQS-GDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGP 2557
Query: 279 STSQ-MGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESA 337
TS+ GS+ + Q H + SGS S + + GS + S +E+ A
Sbjct: 2558 RTSRNWGSSFSQDSDSQG--HSEDSERWSGSASRNHHGS-AQEQLRDGSRHPRSHQEDRA 2614
Query: 338 ASGGAAYTKRYLEEQKTEN------GKDKEQKQTNTDKEKIKEKGSFSD----TGLGDGK 387
G +A + R + T+ EQ +++ + +D +G+G G+
Sbjct: 2615 GHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQ 2674
Query: 388 MKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQD--KDKAKGRKESE 445
S A + + + GSQ+ +D + + H + Q ++ A+GR
Sbjct: 2675 ASS---AVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGET 2731
Query: 446 FDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRG 505
F+ +V + +++ E S W G P + +Q E ++S + ++ +
Sbjct: 2732 SGHSGSFLYQV---STHEQSESSHGWTG----PSTRGRQGSRHEQAQDSSRHSASQDGQD 2784
Query: 506 K------RSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTGKS 559
S GG +G+ E + + + S S TS+ R D G+S
Sbjct: 2785 TIRGHPGSSRGGRQGYHHEHSVDSSGH------SGSHHSHTTSQGR------SDASRGQS 2832
Query: 560 SFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQ---EFRSIFQHIQS 616
+R A R + D +R SG E D+ ++ Q E + S
Sbjct: 2833 G---SRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGS 2889
Query: 617 AQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIH 676
+ SQ S SE ++ +H GS+ L + R +++ A + S +
Sbjct: 2890 SVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRH--PRSHQEDRAGHGHSADSS 2947
Query: 677 RRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDI---ERRKKHKERDLK 733
R+ + G A + R + G + D + RD
Sbjct: 2948 RQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG 3007
Query: 734 RGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAE 793
S S + HS + + + Q+ H+ + R RS +S S
Sbjct: 3008 HRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESA-RGRSGETSGHSGSFL--- 3063
Query: 794 EYTEETEEREESTTGFDKSRLGTKDFVGPSERG 826
Y T E+ ES+ G + GPS RG
Sbjct: 3064 -YQVSTHEQSESSHG----------WTGPSTRG 3085
Score = 75.5 bits (184), Expect = 2e-13
Identities = 203/1021 (19%), Positives = 360/1021 (35%), Gaps = 116/1021 (11%)
Query: 2 SKTNKSKSGSRSSRSRS---ASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAH 58
S +S+ GSR+ RS AS S S+ + + S + SS+ ++RS SP
Sbjct: 1621 SAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARS-SPGE 1679
Query: 59 NRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQN----- 113
H + + G R NRG + G+ S+ Q+
Sbjct: 1680 RHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSE-ESDTQSVSAHG 1738
Query: 114 ----YRQAYSPR-RGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSR 168
++Q++ RG+S RS + S + +H ++ +S+ R+ S+ R S H +
Sbjct: 1739 QAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQS--ESAHGRTGPSTGGRQRSRHEQ 1796
Query: 169 VESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATY 228
S R SA ++ + P + G QG ++ S G S + +S+ D +
Sbjct: 1797 ARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSR 1856
Query: 229 GTGSASRAS--AVSELSPRERSPALKSPLQSVVVRRRSPRPSPV--PKPSPPLSSTSQMG 284
G + S +E + S S R S R S V + S P +S +Q G
Sbjct: 1857 GQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQ-G 1915
Query: 285 STLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAY 344
S++ + Q H + SGS S + + GS + S E+ A G +A
Sbjct: 1916 SSVSQDSDSQG--HSEDSERWSGSASRNHLGSAWEQ-SRDGSRHPGSHHEDRAGHGHSAD 1972
Query: 345 TKRYLEEQKTEN------GKDKEQKQTNTDK-----EKIKEKGSFSDTGLGDGKMKSDSF 393
+ R + TE+ EQ +++ + +++ S +G+G G+ S
Sbjct: 1973 SSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASS--- 2029
Query: 394 APKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQD--KDKAKGRKESEFDDEPK 451
A + + + GSQ+ +D + + + Q K+ A+G+
Sbjct: 2030 AVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGS 2089
Query: 452 FMSKV-----IGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESF---PERSKKED 503
F+ +V + Q +G +G Y + + +++ P S+
Sbjct: 2090 FLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGR 2149
Query: 504 RGKRSE---------GGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDF 554
+G E G H + + +S+S +S D G
Sbjct: 2150 QGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSH 2209
Query: 555 PTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQ-H 613
SS++ + + + S +RP G + HS E+ S + H
Sbjct: 2210 HHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEG--HSEDSERRSGSASRNH 2267
Query: 614 IQSAQSQ-RSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKS 672
SAQ Q R S H H T H + + + E A++
Sbjct: 2268 HGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAG 2327
Query: 673 PEIHRRIDISPSTFRKHGLAHDEMKSP-REPGYK-AEGKYKDDPVDLRLDIE-------- 722
S + R G+ H + S R+ G++ + G D D +
Sbjct: 2328 ERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHG 2387
Query: 723 ----RRKKHKERDLKRGKSRE----SVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRAR 774
++ H+E R R S + S+H + SA T G ++ H++AR
Sbjct: 2388 QAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQAR 2447
Query: 775 DRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTF 834
D SR S+S +E +++ G S G + E+ R+ +
Sbjct: 2448 DSSRHSTS-----------------QEGQDTIHGHPGSSSGGRQ-GSHYEQLVDRSGHSG 2489
Query: 835 QFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDKW 894
+ GR + S ++ + + Q RN E+ D S+ + + G +
Sbjct: 2490 SHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQ- 2548
Query: 895 VSRGRGRGAFPRGRGRFMFRKSSTSPKW--AHDKFSGEEGEIEDDE--SGTENREEKDNI 950
G+G+ PR TS W + + S +G ED E SG+ +R +
Sbjct: 2549 --VGQGQSEGPR-----------TSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSA 2595
Query: 951 Q 951
Q
Sbjct: 2596 Q 2596
Score = 70.9 bits (172), Expect = 6e-12
Identities = 159/828 (19%), Positives = 280/828 (33%), Gaps = 73/828 (8%)
Query: 25 RSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQNRDFRGHNRGYRRPY 84
RS S S ++RSR S S R+R RV Q+RD GH+ R
Sbjct: 259 RSRSSDGKSSSQVNRSRHENTSQVPLQES----RTRKRRGSRVSQDRDSEGHSEDSERHS 314
Query: 85 YFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSR 144
RN W Q +R G + RS+ ++ R S R+S + + + SR
Sbjct: 315 GSASRNHHGSAWEQ-SRDGSRHPRSHDED-------RASHGHSADSSRQSGTRHAETSSR 366
Query: 145 NSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSA--KEKKSSSKDSRPSQAAGDNQGDEAK 202
SS +++R S R S H + S R SA + + SS+ R + + +Q +++
Sbjct: 367 GQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSE 426
Query: 203 ---EQTFSGGTSQDTKASESSKPWPDATYGTG---SASRASAVSELSPRERSPALKSPLQ 256
E + + S KA + ++T G S S++ ++S E+ +
Sbjct: 427 GHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTG 486
Query: 257 SVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSP 316
+ R+ + S S++ + T+ G G QG H S++ S S
Sbjct: 487 TSTGGRQGSHHEQA-RDSSRHSASQEGQDTIRGHPGSSRGGRQG--SHHEQSVNRSGHS- 542
Query: 317 VGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKG 376
+ ++ +SQ A+ G + + + E D + + E +
Sbjct: 543 ------GSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQAD 596
Query: 377 SFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEK---KMADFHKEEMDDQ 433
S + +G G+ S P+T + SQ +D E+ + H +Q
Sbjct: 597 SSRHSQVGQGQ----SSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQ 652
Query: 434 DKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEE 493
+D ++ S +D + K+ G +Q ++ E
Sbjct: 653 SRDGSR-HPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSG---QAASSHEQARSSAGERH 708
Query: 494 SFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGD 553
+ + D + S GH A AV++ S S++ D G D
Sbjct: 709 GSRHQLQSADSSRHSGTGHG----------QASSAVRD--SGHRGSSGSQATDSEGHSED 756
Query: 554 FPTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQE------- 606
T S++ Q S E SG ++ V ++K+ +
Sbjct: 757 SDTQ----SVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGP 812
Query: 607 ---FRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTE 663
R H Q+ + R + Q TI H G G + + G+
Sbjct: 813 STGVRQGSHHEQARDNSRHSASQDGQD--TIRGHPGSSRRGRQGSHHEQSVDRSGHSGSH 870
Query: 664 QEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDIER 723
++ + R S S R R G + + +
Sbjct: 871 HSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQ 930
Query: 724 RKKHKERDLKRGKSRESVDSRDSSHSR--ERSAEKTEKTHKGSKKQKKHRRARDRSRSSS 781
+ R +R S S DS HS ER + + H+GS +++ R R S
Sbjct: 931 GQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQS--RHGSRHPRSH 988
Query: 782 SSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGR 829
++ H + A+ + E+++G + + P ER G R
Sbjct: 989 HEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSR 1036
Score = 69.7 bits (169), Expect = 1e-11
Identities = 175/869 (20%), Positives = 298/869 (34%), Gaps = 87/869 (10%)
Query: 2 SKTNKSKSGSRSSRSRSASRS---RSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAH 58
S +S+ GSR RS R+ S S+ + + S + SS ++RS SP
Sbjct: 973 SAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARS-SPG- 1030
Query: 59 NRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNR----------------- 101
ER+ R Q+ D H+ RR R+ G WG
Sbjct: 1031 --ERHGSRHQQSADSSRHSGIPRRQASSAVRDSGH--WGSSGSQASDSEGHSEESDTQSV 1086
Query: 102 GGYGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSR 161
G+G + Q+++++ R S RS S + + +S+ R+R S+ R
Sbjct: 1087 SGHGQDGPHQQSHQES-----ARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRR 1141
Query: 162 SSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSK 221
S+H + S R SA ++ + + P G QG ++ G S + +S+
Sbjct: 1142 QGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQ 1201
Query: 222 PWPDATYGTGSASRASAVSELSPR--ERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSS 279
DA++G + AS + + + S S S R S V + S
Sbjct: 1202 GRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSR 1261
Query: 280 TSQ-MGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAA 338
TS+ GS++ + S H + SGS S + + GS + +E+ A+
Sbjct: 1262 TSRHQGSSVSQDS--DSERHSDDSERLSGSASRNHHGS-SREQSRDGSRHPGFHQEDRAS 1318
Query: 339 SGGAAYTKRYLEEQKTENG------KDKEQKQTNTDKEKIKEKGSFSDTGLGDG-KMKSD 391
G +A + R TE+ EQ +++ + +D+ G +
Sbjct: 1319 HGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQA 1378
Query: 392 SFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQD--KDKAKGRKESEFDDE 449
S A + + GSQ +D + + H + Q K+ A+G+
Sbjct: 1379 SSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRS 1438
Query: 450 PKFMSKVIGANKNQEEEKSGKWEGLVYAPPG-KEKQRKTEELEEESFPERSKKEDRGKRS 508
F+ +V ++ Q E G+ G + +Q + S + S
Sbjct: 1439 RSFLYQV--SSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSS 1496
Query: 509 EGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQ 568
GG +G E++ + + ++P R D G+S R A
Sbjct: 1497 RGGRQGSYHEQSVDRSGHSGYHHSHTTPQGR------------SDASHGQSG---PRSAS 1541
Query: 569 VNVRMDSFDEDLARPSGLLAQERKL-CRDLVHS--NKKEQEFRSIFQHIQSAQSQRSPSE 625
R + D +R SG E HS + E + S+ SQ SE
Sbjct: 1542 RQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSE 1601
Query: 626 LFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPST 685
++ +H+GS+ R R +++ A + S E R+ +
Sbjct: 1602 GHSEDSERRSESASRNHYGSA--REQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAE 1659
Query: 686 FRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRD 745
G A + R + G D D ++ + +R S S+
Sbjct: 1660 TSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQA 1719
Query: 746 S---SHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEER 802
S HS E + + Q+ H+ + R +S S +S Y T E+
Sbjct: 1720 SDSEGHSEESDTQSVSAHGQAGPHQQSHQES-TRGQSGERSGRSGSFL----YQVSTHEQ 1774
Query: 803 EESTTGFDKSRLGTKDFVGPSERGGGRAR 831
ES G GPS G R+R
Sbjct: 1775 SESAHG----------RTGPSTGGRQRSR 1793
Score = 64.7 bits (156), Expect = 4e-10
Identities = 196/1032 (18%), Positives = 337/1032 (32%), Gaps = 152/1032 (14%)
Query: 5 NKSKSGSRS-SRSRSASRSRSRSFSKSRSRS-RSLSRSRKRRLSSRSRSRSYSPAHNRER 62
NK + + R S R +R +K RS+S R R S + + YSP H RE
Sbjct: 113 NKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKKERKGYSPTH-REE 171
Query: 63 NHPRVYQNRDFRGHNR-------GYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQN-- 113
+ + + N + N+ R+ R + G Y+ G W
Sbjct: 172 EYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSG 231
Query: 114 --------YRQAYSPRRG---------RSRSRSPKRRS-------------PSPRSRSHS 143
+AY RSRS K S P SR+
Sbjct: 232 HIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRK 291
Query: 144 RNSDKSSSDR--------SRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGD 195
R + S DR S R S S S ++H R ++ +S +D + D
Sbjct: 292 RRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSAD 351
Query: 196 NQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPRERSPALKSPL 255
+ + Q + E ++ P +G+G A + R A
Sbjct: 352 SSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADS-------SRHSATGRGQ 404
Query: 256 QSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSG---AGYQSGTHQGQFDHGSGSLSPS 312
S V R R S + S + + SG AG + +HQ SG S
Sbjct: 405 ASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGR 464
Query: 313 KKSPV-------------GKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKD 359
S + G++ STG GS ++ +S +A ++ + + G
Sbjct: 465 SGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSA-SQEGQDTIRGHPGSS 523
Query: 360 KEQKQTNTDKEKIKEKG-SFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDF 418
+ +Q + ++ + G S S + +SD+ ++ S R +++ ++ D
Sbjct: 524 RGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQ---SGDG 580
Query: 419 EKKMADFHKEEMDDQDKDK----AKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGL 474
+ H E D + +G+ + S ++ E S +W G
Sbjct: 581 TRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSG- 639
Query: 475 VYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSS 534
+ E+ + S RS EDR GH + R + + Q SS
Sbjct: 640 --SASRNHHGSAQEQSRDGSRHPRSHHEDRAGH---GHSA----DSSRKSGTRHTQNSSS 690
Query: 535 SPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSGL-LAQERKL 593
++R G + R D +R SG Q
Sbjct: 691 GQAASSHEQARSSAGERH-----------------GSRHQLQSADSSRHSGTGHGQASSA 733
Query: 594 CRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHER 653
RD H + H + + +Q H HH S + +R
Sbjct: 734 VRDSGHRGSSGSQATDSEGHSEDSDTQSVSG-----------HGQAGHHQQSHQESARDR 782
Query: 654 FTKYLKRGTE--QEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGK-- 709
+ +R + + +K+S H PST + G H++ + +G+
Sbjct: 783 SGERSRRSGSFLYQVSTHKQSESSHGW--TGPSTGVRQGSHHEQARDNSRHSASQDGQDT 840
Query: 710 YKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSR---------ERSAEKTEKT 760
+ P R R+ H E+ + R S S +S R RSA +T +
Sbjct: 841 IRGHPGSSRRG--RQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRN 898
Query: 761 HKGSKKQKKHRRARDRSRSSSSS-SQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDF 819
+ S+ +H +R SS + S+ S + + + T R+ S+ D G +
Sbjct: 899 EEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSE- 957
Query: 820 VGPSERGGGRA----RGTFQFRAR-GRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYT 874
SER G A RG+ Q ++R G R ++ + + D +++ E +
Sbjct: 958 --DSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPH--AETS 1013
Query: 875 PKSKKYYLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSST---SPKWAHDKFSGEE 931
+ H+ ++ SR + R G + SS S W +
Sbjct: 1014 SGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASD 1073
Query: 932 GEIEDDESGTEN 943
E +ES T++
Sbjct: 1074 SEGHSEESDTQS 1085
Score = 63.5 bits (153), Expect = 9e-10
Identities = 171/865 (19%), Positives = 289/865 (33%), Gaps = 88/865 (10%)
Query: 2 SKTNKSKSGSRSSRSRSASRS-RSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNR 60
S +S+ GSR S R+ S SR + S R ++ S ++ S A R
Sbjct: 1945 SAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGER 2004
Query: 61 ERNHPRVYQNRDFRGHN---RGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQA 117
+H ++ Q+ D H+ G +RG+ + G+ Q
Sbjct: 2005 HGSHHQL-QSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQG 2063
Query: 118 YSPRRGRSRSRSPKRRSPSPRSRSHS-------RNSDKSSSDRSRRSSSSRSSSNHSRVE 170
+ +S S + +S RS S +S+ +S S+ R S++ + +
Sbjct: 2064 KAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQ 2123
Query: 171 SSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDAT--- 227
S R SA ++ + P + G QG ++ G S + +S+ DA+
Sbjct: 2124 DSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQ 2183
Query: 228 YGTGSASRASAVSELS----------PRERSPALKSPLQSVVVRRRS-------PRPSPV 270
G+ SASR + E S E S S S+V + +S PR S V
Sbjct: 2184 SGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSV 2243
Query: 271 PKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGS 330
+ S + S + G+ Q Q GS + G + S
Sbjct: 2244 SQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSG 2303
Query: 331 SQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKS 390
+ E+++ G AA + E Q+ ++ + +G+G G+ S
Sbjct: 2304 THHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRH----------SGIGHGQASS 2353
Query: 391 DSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQD--KDKAKGRKESEFDD 448
A + + GSQ+ +D + + H + Q ++ +GR
Sbjct: 2354 ---AVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGR 2410
Query: 449 EPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGK-EKQRKTEELEEESFPERSKKEDRGKR 507
F+ +V + Q E G+ G KQ + S +
Sbjct: 2411 SGSFLYQV--STHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGS 2468
Query: 508 SEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREA 567
S GG +G E+ + + S S TS+ R D G S +R A
Sbjct: 2469 SSGGRQGSHYEQLVDRSGH------SGSHHSHTTSQGR------SDASHGHSG---SRSA 2513
Query: 568 QVNVRMDSFDEDLARPSGLLAQERKLCRDLV-HS--NKKEQEFRSIFQHIQSAQSQRSPS 624
R D D +R SG E D HS + + E ++ S+ SQ S S
Sbjct: 2514 SRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDS 2573
Query: 625 ELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPS 684
+ ++ +H GS+ L + R +++ A + S + R+ +
Sbjct: 2574 QGHSEDSERWSGSASRNHHGSAQEQLRDGSRH--PRSHQEDRAGHGHSADSSRQSGTRHT 2631
Query: 685 TFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDI---ERRKKHKERDLKRGKSRESV 741
G A + R + G + D + RD S
Sbjct: 2632 QTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQ 2691
Query: 742 DSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEE 801
S + HS + + + Q+ H+ + R RS +S S Y T E
Sbjct: 2692 ASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESA-RGRSGETSGHSGSFL----YQVSTHE 2746
Query: 802 REESTTGFDKSRLGTKDFVGPSERG 826
+ ES+ G + GPS RG
Sbjct: 2747 QSESSHG----------WTGPSTRG 2761
Score = 60.5 bits (145), Expect = 7e-09
Identities = 190/1009 (18%), Positives = 334/1009 (33%), Gaps = 121/1009 (11%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRE 61
S + +SG+R +++ S ++ S S ++RS + R S SR H +
Sbjct: 2943 SADSSRQSGTRHTQTSSGGQAAS---SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQA 2999
Query: 62 RNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPR 121
+ R +R + G + + GQ S+ Q+++++
Sbjct: 3000 SSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAG--------SHQQSHQES---A 3048
Query: 122 RGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKK 181
RGRS S S + +H ++ +SS + S+ R S H + + S R SA +
Sbjct: 3049 RGRSGETSGHSGSFLYQVSTHEQS--ESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYG 3106
Query: 182 SSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDAT---YGTGSASRASA 238
+ P + G QG + S G S + +S+ DA+ G+ SASR +
Sbjct: 3107 QDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTR 3166
Query: 239 VSELS--------PRERSPALKSPL---------QSVVVRRRSPRPSPVPKPSPPLSSTS 281
E S R + + + QS RR + S V + S +
Sbjct: 3167 NEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSE 3226
Query: 282 QMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGG 341
S + G+ Q Q HGS + G + S ++ E+++ G
Sbjct: 3227 DSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQ 3286
Query: 342 AAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEK 401
AA + E + Q+ ++ + +G S + + D + S + +DSE
Sbjct: 3287 AASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQAS-SAVRDSRHWGSSGSQASDSEG 3345
Query: 402 PFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANK 461
S + + A H++ + +D++ GR F+ +V
Sbjct: 3346 HSEESDT------QSVSGHGQAGPHQQSHQESARDRSGGRS----GRSGSFLYQV----- 3390
Query: 462 NQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRG------- 514
E+S G G+ + E+ + S R G+ + GH G
Sbjct: 3391 -STHEQSESAHGRTRTSTGRRQGSHHEQARDSS---RHSASQEGQDTIRGHPGSSRRGRQ 3446
Query: 515 ------FVPEKNFRVTAYKAVQEKSSSPPPRKTSESR--------DKLGAKGDFPTGKSS 560
V + + + S R S SR D+ G +
Sbjct: 3447 GSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHH 3506
Query: 561 FSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFR----SIFQHIQS 616
+ +A + S A P Q + +D E R + H S
Sbjct: 3507 HEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGS 3566
Query: 617 AQSQ-RSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEI 675
AQ Q R S H H T H + + + E A++
Sbjct: 3567 AQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERH 3626
Query: 676 HRRIDISPSTFRKHGLAHDEMKSP-REPGYK-AEGKYKDDPVDLRLDIE----------- 722
S + R G+ H + S R+ G++ + G D D +
Sbjct: 3627 GSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAG 3686
Query: 723 -RRKKHKERDLKRGKSRE----SVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRS 777
++ H+E R R S + S+H + SA G ++ +H +ARD S
Sbjct: 3687 PHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSS 3746
Query: 778 RSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFR 837
R S+S +E +++ G SR G + E+ R+ +
Sbjct: 3747 RHSAS-----------------QEGQDTIRGHPGSRRGGRQ-GSYHEQSVDRSGHSGSHH 3788
Query: 838 ARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDKWVSR 897
+ GR + S + + + + RN E+ D S+ H+ S +
Sbjct: 3789 SHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRH---HEASTQADSSRHSQS 3845
Query: 898 GRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREE 946
G+G A R R S S A+ + S E +RE+
Sbjct: 3846 GQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQ 3894
Score = 56.6 bits (135), Expect = 1e-07
Identities = 91/373 (24%), Positives = 144/373 (38%), Gaps = 48/373 (12%)
Query: 8 KSGSRSSRSRSASRS-RSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPR 66
+S S+R RSA RS RS SF S + S S R + R S H + R+ R
Sbjct: 3690 QSHQESTRGRSAGRSGRSGSFLYQVS-THEQSESAHGRAGPSTGGRQGS-RHEQARDSSR 3747
Query: 67 VYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSR 126
+++ + RG+ P RG +G Y +R G+ + + G+S
Sbjct: 3748 HSASQEGQDTIRGH--PGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSG 3805
Query: 127 SRSPKRRSPS-PRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSK 185
SRS R + + +S SR+S + S ++ SSR S + + R+S ++ S S+
Sbjct: 3806 SRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQ 3865
Query: 186 DS----------RPSQAAGDNQGDEAKEQT-----FSGGTSQDTKASESSKPWPDATYGT 230
DS R S++A N ++EQ+ G + +DT + S P
Sbjct: 3866 DSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSP------VQ 3919
Query: 231 GSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSG 290
+S A S + A S +QS R SP S S SG
Sbjct: 3920 SDSSTAKEHGHFSSLSQDSAYHSGIQS--------RGSPHSSSSYHYQSEGTERQKGQSG 3971
Query: 291 AGYQSGTH-QGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQ---KEESAASGGAAYTK 346
++ G++ +D+G S+ V +Y S+ KE S +A+ K
Sbjct: 3972 LVWRHGSYGSADYDYGESGFRHSQHGSV---------SYNSNPVVFKERSDICKASAFGK 4022
Query: 347 RYLEEQKTENGKD 359
+ T KD
Sbjct: 4023 DHPRYYATYINKD 4035
Score = 52.8 bits (125), Expect = 2e-06
Identities = 183/971 (18%), Positives = 307/971 (31%), Gaps = 120/971 (12%)
Query: 8 KSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRV 67
K +R S+ RS S + S + + + + Y A + R+
Sbjct: 2073 KESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQ 2132
Query: 68 YQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRS 127
RGH P RG +G + +R G+ + + RG+S S
Sbjct: 2133 EGQDTIRGH------PGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGS 2186
Query: 128 RSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRV----ESSKRKSAKEKKSS 183
RS R++ + S + + S +SS SS HS V S R S S
Sbjct: 2187 RSASRKT---YDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSV 2243
Query: 184 SKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWP--DATYGTGSASRASAVSE 241
S+DS + D++ G++Q+ S P + G G ++ +S S
Sbjct: 2244 SQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSG 2303
Query: 242 LSPRERSPALKSPLQSVVVRRRS-PRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQG 300
E S ++ R + R + S S S +G S A SG
Sbjct: 2304 THHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGS 2363
Query: 301 QFDHGSGSLSPSKKSPV------GKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKT 354
S S S+ S G++ P S S++ + SG + +L + T
Sbjct: 2364 SGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSG---SFLYQVST 2420
Query: 355 ENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKP--FRGSQSPKRY 412
+ +T T +GS + + T P G + Y
Sbjct: 2421 HEQSESAHGRTGTSTGG--RQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHY 2478
Query: 413 KLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEF------DDEPKFMSKVIGANKNQEEE 466
+ D H D + G S +DE +++ E
Sbjct: 2479 EQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEAS 2538
Query: 467 KSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAY 526
G G+ + +T SF + S + + SE +N +A
Sbjct: 2539 SRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGS--ASRNHHGSAQ 2596
Query: 527 KAVQEKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSGL 586
+ Q + S PR E R G D S S TR Q + G
Sbjct: 2597 E--QLRDGSRHPRSHQEDRAGHGHSAD----SSRQSGTRHTQTS------------SGGQ 2638
Query: 587 LAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSS 646
A + R R H QSA S R Q + H G S
Sbjct: 2639 AASSHEQARSSAGE-------RHGSHHQQSADSSRHSGIGHGQASSAVRD---SGHRGYS 2688
Query: 647 GMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKA 706
G +A+ N+ E D + HG A +S +E
Sbjct: 2689 G----------------SQASDNEGHSE-----DSDTQSVSAHGQAGSHQQSHQESARGR 2727
Query: 707 EGKYKDDPVDLRLDIERRKKHKERD-----LKRGK--SRESVDSRDSSHSRERSAEKTEK 759
G+ + ++ + RG+ SR S HS + + T +
Sbjct: 2728 SGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIR 2787
Query: 760 THKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDF 819
H GS + + + S SS S S HS+ ++ R +++ G SR ++
Sbjct: 2788 GHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTT------SQGRSDASRGQSGSRSASRTT 2841
Query: 820 VGPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKK 879
+ G G R + S ++ +++ D + ++ + E + +S++
Sbjct: 2842 RNEEQSGDG---------------SRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRR 2886
Query: 880 Y--YLHDDREGEGSDKWVSRGRGRGA-FPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIED 936
+ D + EG + R G + G + R S P+ +H + G D
Sbjct: 2887 QGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPR-SHQEDRAGHGHSAD 2945
Query: 937 D--ESGTENRE 945
+SGT + +
Sbjct: 2946 SSRQSGTRHTQ 2956
Score = 47.8 bits (112), Expect = 5e-05
Identities = 171/914 (18%), Positives = 303/914 (33%), Gaps = 125/914 (13%)
Query: 121 RRG-RSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSK------ 173
R+G + RS+SP+ S + K S R ++ N S+ E +K
Sbjct: 134 RKGNKGRSKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRL 193
Query: 174 ---RKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGT 230
RK E+ +D+ +N G ++ SG + + + D
Sbjct: 194 GDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTD----- 248
Query: 231 GSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSG 290
S + E ERS + S V R R S VP + + GS +
Sbjct: 249 ------SLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQES--RTRKRRGSRVSQD 300
Query: 291 AGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLE 350
S H + SGS S + + GS + S E+ A+ G +A + R
Sbjct: 301 R--DSEGHSEDSERHSGSASRNHHGSAWEQ-SRDGSRHPRSHDEDRASHGHSADSSR--- 354
Query: 351 EQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKS-DSFAPKTDSEKPFRGSQSP 409
+ T + + + QT + E+ + S G G +S DS + S
Sbjct: 355 QSGTRHAETSSRGQTASSHEQAR---SSPGERHGSGHQQSADSSRHSATGRGQASSAVSD 411
Query: 410 KRYKLRDDFEKKMADFHKEEMDDQD---KDKAKGRKESEFDDEPKFMSKVIGANKN---- 462
+ ++ + ++ H E D Q KA R++S + + G + +
Sbjct: 412 RGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQ 471
Query: 463 -QEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKK----------EDRGKRS--- 508
E+ G G + E+ + S S++ RG R
Sbjct: 472 VSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSH 531
Query: 509 ----------EGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGD-FPTG 557
G H + ++ +S+S R +S D G
Sbjct: 532 HEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEA 591
Query: 558 KSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQ-HIQS 616
S +R +QV S ++Q+ HS E+ S + H S
Sbjct: 592 SSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSD---SQGHSEDSERWSGSASRNHHGS 648
Query: 617 AQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKN-----KK 671
AQ Q + HH G S + + T++ + + +AA +
Sbjct: 649 AQEQSRDGSRHPRS-----HHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSS 703
Query: 672 SPEIH--RRIDISPSTFRKHGLAHDEMKSP-REPGYK---------AEGKYKDDPVDLRL 719
+ E H R S + R G H + S R+ G++ +EG +D
Sbjct: 704 AGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVS 763
Query: 720 DIERRKKHKERDLKRGKSRESVDSRD--------SSHSRERSAEKTEKTHKGSKKQKKHR 771
+ H++ + + R SR S+H + S+ G ++ H
Sbjct: 764 GHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHE 823
Query: 772 RARDRSRSSSSSS----------------QSSHSYKAEEYTEETEEREESTTGFDKSRLG 815
+ARD SR S+S Q SH ++ + + + TT +S
Sbjct: 824 QARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSD-- 881
Query: 816 TKDFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTP 875
+ G A T + + R R + S ++ +S+ D + ++ + E +
Sbjct: 882 ----ASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSR 937
Query: 876 KSKKY--YLHDDREGEGSDKWVSRGRGRGA-FPRGRGRFMFRKSSTSPKWAHDKFSGEEG 932
S++ + D + EG + R G + RG + R S P+ H+ +G
Sbjct: 938 TSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGH 997
Query: 933 EIEDD-ESGTENRE 945
+ +SGT + E
Sbjct: 998 SADSSRQSGTPHAE 1011
Score = 44.3 bits (103), Expect = 6e-04
Identities = 54/258 (20%), Positives = 91/258 (35%), Gaps = 22/258 (8%)
Query: 122 RGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKK 181
RGRS RS + S + +H ++ +S+ R+ S+ R S H + S R SA ++
Sbjct: 3697 RGRSAGRSGRSGSFLYQVSTHEQS--ESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEG 3754
Query: 182 SSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSE 241
+ P G QG ++ G S + +S+ DA++G +
Sbjct: 3755 QDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGS-------- 3806
Query: 242 LSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQ 301
R S ++ QS R S S SQ G AG + QG
Sbjct: 3807 ---RSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQ--GESAGSRRSRRQGS 3861
Query: 302 FDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKE 361
+ +S ++ + +GSS+++ S R+ + +
Sbjct: 3862 SVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGS-------RHPGSSHRDTASHVQ 3914
Query: 362 QKQTNTDKEKIKEKGSFS 379
+D KE G FS
Sbjct: 3915 SSPVQSDSSTAKEHGHFS 3932
Score = 42.0 bits (97), Expect = 0.003
Identities = 58/281 (20%), Positives = 105/281 (37%), Gaps = 26/281 (9%)
Query: 679 IDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSR 738
+ IS RKH HD+ + ++ K K +ERR K + R
Sbjct: 94 LPISGHKHRKHS-HHDKHEDNKQEENKENRKRPSS-------LERRNNRKGNKGRSKSPR 145
Query: 739 ESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYK-AEEYTE 797
E+ R S S ++ + TH+ + K H + + ++ + +++ + K E E
Sbjct: 146 ETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLE 205
Query: 798 ETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRA---------RGRGWGRGNY 848
E E+ EE ++ + T+ ++ + G T Q A + + R
Sbjct: 206 EKEDNEEGVYDYENTGRMTQKWI---QSGHIATYYTIQDEAYDTTDSLLEENKIYERSRS 262
Query: 849 S-GNNNNNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDKWVSRGRGRGA-FPR 906
S G +++ N + + T K + + DR+ EG + R G +
Sbjct: 263 SDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHH 322
Query: 907 GRGRFMFRKSSTSPKWAHDKFSGEEGEIEDD--ESGTENRE 945
G R S P+ +HD+ G D +SGT + E
Sbjct: 323 GSAWEQSRDGSRHPR-SHDEDRASHGHSADSSRQSGTRHAE 362
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 79.0 bits (193), Expect = 2e-14
Identities = 136/739 (18%), Positives = 232/739 (31%), Gaps = 25/739 (3%)
Query: 127 SRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKD 186
S S S S S S +SD SSD S SS S+S+ S S S+ SS
Sbjct: 564 SDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSK 623
Query: 187 SRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPRE 246
S S++ D+ ++K + +S + S+SS + S S S+ S S
Sbjct: 624 SDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDS 683
Query: 247 RSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGS 306
+ + S S S S SS S S S S + S
Sbjct: 684 SNSSDSSDSSD---SSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS 740
Query: 307 GSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTN 366
S S S + + SS +S+ S ++ + + + N D +
Sbjct: 741 SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNS 800
Query: 367 TDKEKIKEKGSFSDTGLGDGKMKSDS--FAPKTDSEKPFRGSQSPKRYKLRDDFEKKMAD 424
+D + SD+ D SDS + +DS S S D +D
Sbjct: 801 SDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSD 860
Query: 425 F--HKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKE 482
+ D D + +S +E S ++ + + + S + +
Sbjct: 861 SSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSN----SSDSSD 916
Query: 483 KQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTS 542
++ E + + S D S+ N ++ + SS +S
Sbjct: 917 SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSS--DSSNSSDSSNSSDSSNSSDSSDSNSS 974
Query: 543 ESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNK 602
+S D + + SS S N S D + S + + D +S+
Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSN--SSDSSNSSDSSNSSD 1032
Query: 603 KEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGT 662
S S S S S + + SS + +
Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092
Query: 663 EQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLDIE 722
+++ + S + D S S+ + + ++ D D +
Sbjct: 1093 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSD 1152
Query: 723 RRKKHKERDLK-RGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRS-- 779
D S +S DS DSS+S + S S + D S S
Sbjct: 1153 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1212
Query: 780 SSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRAR 839
SS SS SS S + + ++ E + S + + D S+ + + ++
Sbjct: 1213 SSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQ 1272
Query: 840 GRGWGRGNYSGNNNNNSNN 858
+ SGN NNN ++
Sbjct: 1273 SK-------SGNGNNNGSD 1284
Score = 71.6 bits (174), Expect = 3e-12
Identities = 82/446 (18%), Positives = 145/446 (32%), Gaps = 17/446 (3%)
Query: 119 SPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAK 178
S RS S + S S S + S +SD S S+ S SS S SSN S +SS ++
Sbjct: 853 SDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS 912
Query: 179 EK--KSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRA 236
+ S+S DS S + DN + S D+ S S D++ + S+
Sbjct: 913 DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 972
Query: 237 SAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSG 296
S+ S S + S S S S S++ S+ S + S
Sbjct: 973 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSD 1032
Query: 297 THQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTEN 356
+ S S S S + + + SS +S+ S ++ + + + N
Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092
Query: 357 GKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRD 416
D ++D + SD+ S + +DS S S + D
Sbjct: 1093 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSD 1152
Query: 417 DFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVY 476
+ + + D D + S + S ++ + + S
Sbjct: 1153 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1212
Query: 477 APPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSP 536
+ + ++ + E S D S+ + + SS
Sbjct: 1213 SSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSN---------------SSDSSDSSD 1257
Query: 537 PPRKTSESRDKLGAKGDFPTGKSSFS 562
TS+S D+ ++ G ++ S
Sbjct: 1258 SSDSTSDSNDESDSQSKSGNGNNNGS 1283
Score = 62.8 bits (151), Expect = 1e-09
Identities = 89/468 (19%), Positives = 150/468 (32%), Gaps = 2/468 (0%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRE 61
S ++ S + S SS S ++S S S S S S S +RS S S S S + +
Sbjct: 821 SNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS 880
Query: 62 RNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPR 121
+ + + + N ++ N + S
Sbjct: 881 DSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSN 940
Query: 122 RGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKK 181
S S S + S S NS SS S SS S +SS+ S S S
Sbjct: 941 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1000
Query: 182 SSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSE 241
S+S DS S + D+ + S D+ S S D++ + S+ +++
Sbjct: 1001 SNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1060
Query: 242 LSPRERSPALKSPLQSVVV-RRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQG 300
+ S + S S S S S S+ S+ S + S +
Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1120
Query: 301 QFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDK 360
S S S S + + + SS +S+ S ++ + + + + +
Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1180
Query: 361 EQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEK 420
++D + SD+ S + +DS S S + D +
Sbjct: 1181 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDS 1240
Query: 421 KMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKS 468
+ D D + S+ +DE SK N N + S
Sbjct: 1241 SDSSDSSNSSDSSDSSDSSD-STSDSNDESDSQSKSGNGNNNGSDSDS 1287
Score = 61.6 bits (148), Expect = 3e-09
Identities = 85/461 (18%), Positives = 149/461 (32%), Gaps = 26/461 (5%)
Query: 125 SRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRS-------SSNHSRVESSKRKSA 177
S S S S S S +SD S SD S RS SS S S++S S S
Sbjct: 827 SNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS--SDSSDSSD 884
Query: 178 KEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRAS 237
+ S+S DS S + D+ ++ + S +S + +SESS ++ S S S
Sbjct: 885 SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944
Query: 238 AVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGT 297
+ S S + S + S S S++ S+ S + S +
Sbjct: 945 SDSSDSSNSSDSSNSSD-------SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDS 997
Query: 298 HQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENG 357
S S S S ++ + SS +S+ S ++ + + + N
Sbjct: 998 SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1057
Query: 358 KDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDD 417
D ++D + SD+ S + + +DS S S D
Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117
Query: 418 FEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYA 477
+ + + D D + +S E S ++ + + S +
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177
Query: 478 PPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPP 537
+ ++ + + S D S+ + + + S S
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS----------DSSDSSD 1227
Query: 538 PRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDE 578
++ES D + + SS S + DS DE
Sbjct: 1228 SSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDE 1268
Score = 61.6 bits (148), Expect = 3e-09
Identities = 86/449 (19%), Positives = 146/449 (32%), Gaps = 3/449 (0%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRE 61
S ++ S GS S S + S S S S S S S + S S S + N
Sbjct: 842 SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS 901
Query: 62 RNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPR 121
+ N + + N + + + + S
Sbjct: 902 DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961
Query: 122 RGRSRSRSPKRRSPSPRSRSHSRNSDKS-SSDRSRRSSSSRSSSNHSRVESSKRKSAKEK 180
S S S S S + S +SD S SSD S S SS SS + +SS ++ +
Sbjct: 962 SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021
Query: 181 KSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVS 240
+SS S S ++ + ++ + + S +S + +S+SS + S S S+ S
Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081
Query: 241 ELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQG 300
S + S S S S S++ S+ S + S +
Sbjct: 1082 SESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 1141
Query: 301 QFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDK 360
S S S S + + SS +S+ S ++ + + + + D
Sbjct: 1142 SDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1201
Query: 361 EQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEK 420
++D + SD+ S+ + +DS S S D +
Sbjct: 1202 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDS 1261
Query: 421 KMADFHKEEMDDQDKDKAKGRKESEFDDE 449
+E D Q K S+ D +
Sbjct: 1262 --TSDSNDESDSQSKSGNGNNNGSDSDSD 1288
Score = 59.3 bits (142), Expect = 2e-08
Identities = 120/679 (17%), Positives = 215/679 (31%), Gaps = 31/679 (4%)
Query: 125 SRSRSPKRRSPSPRSRSHSRNSDKS----SSDRSRR-----SSSSRSSSNHSRVESSKRK 175
S S+S S S S +S +SD S SSD S SSSS SSN S S
Sbjct: 636 SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS 695
Query: 176 SAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASR 235
S + S S DS S ++ + + S D+ S +S D++ + S+
Sbjct: 696 SNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDS 755
Query: 236 ASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQS 295
+ + + + S + S S S S S++S ++ S S
Sbjct: 756 SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDS 815
Query: 296 GTHQGQFDHGSGSLSPSKKS-----PVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLE 350
S + S S S S S GS SS + +S+ S ++ +
Sbjct: 816 SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN 875
Query: 351 EQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPK 410
+ + D + ++D + + SD+ D SDS + ++S S S
Sbjct: 876 SSDSSDSSDSNESSNSSDS---SDSSNSSDSDSSDSSNSSDS-SDSSNSSDSSESSNSSD 931
Query: 411 RYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGK 470
D + + + D + S + +N + + S
Sbjct: 932 NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS 991
Query: 471 WEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQ 530
+ + + ++ + + S D S+ + + + + +
Sbjct: 992 SD----SSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDS-S 1046
Query: 531 EKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQE 590
+ S S +S+S D + + SS S + S D + S + +
Sbjct: 1047 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD--SSD 1104
Query: 591 RKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTL 650
D S+ S S S S S + + SS +
Sbjct: 1105 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSD 1164
Query: 651 HERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKY 710
+ ++ + S + D S S+ + + ++
Sbjct: 1165 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1224
Query: 711 KDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKH 770
D D + D S S DS DSS S + +++ +++ SK +
Sbjct: 1225 SSDSSDSNESSDSSDSSDSSD-----SSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGN 1279
Query: 771 RRARDRSRSSSSSSQSSHS 789
D S S S S S+HS
Sbjct: 1280 NNGSD-SDSDSEGSDSNHS 1297
Score = 58.9 bits (141), Expect = 2e-08
Identities = 124/720 (17%), Positives = 218/720 (30%), Gaps = 49/720 (6%)
Query: 109 SNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSN--- 165
SN + + S SR + S + + S + D S ++ S SN
Sbjct: 471 SNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNG 530
Query: 166 ------HSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASES 219
+ + +S K KS SS S S ++ + D + + S S D+ +S+S
Sbjct: 531 NNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDS 590
Query: 220 SKPWPDATYGTGSASRASAVSELSPRERSPALK---SPLQSVVVRRRSPRPSPVPKPSPP 276
S + + +S +S S+ S S K S +S S S S
Sbjct: 591 SDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDS 650
Query: 277 LSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEES 336
++ S+ S + S + S S S S ++ + SS +S
Sbjct: 651 SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDS 710
Query: 337 AASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTG-LGDGKMKSDS--F 393
+S + + + + N D ++D + + SD+ D SDS
Sbjct: 711 DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770
Query: 394 APKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFM 453
+ +DS S S D + + D D + S D
Sbjct: 771 SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSS 830
Query: 454 SKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHR 513
+N + + S +G + + + + S + S D S+
Sbjct: 831 DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSS--DSSNSSDSSDSSDSNE- 887
Query: 514 GFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRM 573
N ++ + S S +S+S D + + SS + N
Sbjct: 888 ----SSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD 943
Query: 574 DSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVT 633
S D + S SN + S S+ S S +
Sbjct: 944 SSDSSDSSNSSD-------------SSNSSDSSNSSDSSDSNSSDSSDSSNS-------- 982
Query: 634 IVHHVKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAH 693
SS + + +++ + S + D S S+
Sbjct: 983 ---SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDS 1039
Query: 694 DEMKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERS 753
+ + ++ D D + D S ES DS DSS+S + S
Sbjct: 1040 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD--SSDSSESSDSSDSSNSSDSS 1097
Query: 754 AEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAE-EYTEETEEREESTTGFDKS 812
S + D S SS SS S S ++ + ++ + ES+ D S
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSS 1157
Score = 55.8 bits (133), Expect = 2e-07
Identities = 120/690 (17%), Positives = 230/690 (33%), Gaps = 32/690 (4%)
Query: 137 PRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKK-------SSSKDSRP 189
P S S +D ++S+ S +SSSR ++++ ES + + K S+ D+
Sbjct: 465 PNSSDESNGNDDANSE-SDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNN 523
Query: 190 SQAAGD-NQGDEAKEQTFSG-----GTSQDTKASESSKPWPDATYGTGSASRASAVSELS 243
S + G+ N G++ +++ SG + D+ S +S D++ S S +S+ S+ S
Sbjct: 524 SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSS 583
Query: 244 PRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPL-SSTSQMGSTLPSGAGYQSGTHQGQF 302
+ S + S S S S SS S+ S+ S +
Sbjct: 584 DSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSS 643
Query: 303 DHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQ 362
D S S + S + ++ + SS +S++S ++ + + + N +
Sbjct: 644 DSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSD 703
Query: 363 KQTNTDKEKI-KEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKK 421
++D + S S++ D SDS +DS S S D +
Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDS----SDSSNSSDSSDSSDSSNSSDSSDSS 759
Query: 422 MADFHKEEMDDQD-KDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPG 480
+ + D D D + S+ +D +N + S + +
Sbjct: 760 DSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSD 819
Query: 481 KEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRK 540
+ + S S S G ++ + + + S S
Sbjct: 820 SSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS-SDSSDSSNSSD 878
Query: 541 TSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHS 600
+S+S D + + SS S ++ DS + + S + + +S
Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSS-----DSSNSSDSSDSSNSSDSSESSNSSDNS 933
Query: 601 NKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKR 660
N + S S+ S S + + SS + +
Sbjct: 934 NSSDSSNSS--DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS 991
Query: 661 GTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKDDPVDLRLD 720
+++ + S + D S S+ + + + ++ D D
Sbjct: 992 SDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1051
Query: 721 IERRKKHKERDLK-RGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRS 779
+ D S +S DS DSS S E S S + D S S
Sbjct: 1052 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDS 1111
Query: 780 --SSSSSQSSHSYKAEEYTEETEEREESTT 807
SS SS SS+S + + ++ ++ + S +
Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 1141
Score = 43.9 bits (102), Expect = 7e-04
Identities = 120/704 (17%), Positives = 220/704 (31%), Gaps = 75/704 (10%)
Query: 119 SPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAK 178
+P G SPS + + + SS+N E
Sbjct: 230 TPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKED 289
Query: 179 EKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASA 238
+ SS + S+ D +G E G + +K+ E+S P+ + R
Sbjct: 290 DHDSSIGQNSDSKEYYDPEGKEDPHNEVDG--DKTSKSEENSAGIPE----DNGSQRIED 343
Query: 239 VSELSPRERSPA---LKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQS 295
+L+ RE + ++ V + + + P S+ T G G +
Sbjct: 344 TQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGP-----SSGNRNITKEVGKGNEG 398
Query: 296 GTHQGQFDH--GSGSLSP-----SKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRY 348
+GQ G G++ + + P KS P G+ G S + S G Y
Sbjct: 399 KEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEP--GNKVGHSNTGSDSNSDG---YDSY 453
Query: 349 LEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQS 408
+ K+ G D + + + + + GD SD +S+ GS S
Sbjct: 454 DFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSD------ESKDNGNGSDS 507
Query: 409 PKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKS 468
+ +D D D S+ S G N N + +KS
Sbjct: 508 -------------------KGAEDDDSDSTSDTNNSD--------SNGNGNNGNDDNDKS 540
Query: 469 GKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKA 528
+G + +S S + S+ + +
Sbjct: 541 DSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSN 600
Query: 529 VQEKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSGLLA 588
+ S S +S+S D +K D SS S + + + + DS D + + S
Sbjct: 601 SSDSSDSSDSSDSSDSSDSSDSKSD-----SSKSESDSSDSDSKSDSSDSNSSDSS---- 651
Query: 589 QERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGM 648
+ D +S+ S S+ S S S + + SS
Sbjct: 652 -DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDS 710
Query: 649 TLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEG 708
+ ++ +++ + S + D S S+ + + ++
Sbjct: 711 DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770
Query: 709 KYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQK 768
D D + D S +S +S DSS+S + S++ ++ + S
Sbjct: 771 SDSSDSSDSSNSSDSNDSSNSSD-----SSDSSNSSDSSNSSD-SSDSSDSSDSDSSNSS 824
Query: 769 KHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKS 812
+ D S SS+SS S S ++ ++ R +S+ D S
Sbjct: 825 DSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS 868
Score = 35.8 bits (81), Expect = 0.20
Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 5/93 (5%)
Query: 125 SRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSS 184
S S S S S S +SD + S S SS S SSN S +SS + + S S
Sbjct: 1208 SDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSS--DSSDSSDSSDSTSDS 1265
Query: 185 KDSRPSQAA---GDNQGDEAKEQTFSGGTSQDT 214
D SQ+ G+N G ++ + ++ T
Sbjct: 1266 NDESDSQSKSGNGNNNGSDSDSDSEGSDSNHST 1298
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 79.0 bits (193), Expect = 2e-14
Identities = 161/734 (21%), Positives = 287/734 (39%), Gaps = 78/734 (10%)
Query: 113 NYRQAYSPRRGRSRSRSPKRRSPSPRSRSH-----SRNSDKSSSDRSRRSSSSRSSSNHS 167
N++ Y + + KR+ S S S +++ S + +R + S SS+ S
Sbjct: 722 NHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDS 781
Query: 168 RVES-----SKRKSAKEKKS---------SSKDSRPSQAAGDNQGDEAKEQTFSGGTSQD 213
+E SK +A+ K SS+D + S+ DNQG + +T G+S D
Sbjct: 782 ELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHK-NLKTSQEGSSDD 840
Query: 214 TKASESSKPWPDATYGTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKP 273
+ + + + A G+ + + + EL R+R P + + S V K
Sbjct: 841 AERKQERETFSSAE---GTVDKDTTIMEL--RDRLPKKQ---------QASASTDGVDK- 885
Query: 274 SPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQK 333
LS Q ++L ++ + S + + + +S+
Sbjct: 886 ---LSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSED 942
Query: 334 EESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSF 393
++ + G K+ + +K +++ + ++ EK+ E+ G ++K+ +
Sbjct: 943 DKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTT 1002
Query: 394 APKTDSEKPFRGSQSPKRYKLRDDFEKKMA--DFHKEEMDDQDKDKAKGRKESEFDDEPK 451
+ S+K R S K+ +L D EK D D + K+ A GR++ K
Sbjct: 1003 DGEKKSKK-IRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGK 1061
Query: 452 FMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEE---SFPERSKKEDRGKRS 508
K + + E+ S K +G +K+ K EL E S +K+ G S
Sbjct: 1062 SSRKRQDCSSSDTEKYSMKEDGC----NSSDKRLKRIELRERRNLSSKRNTKEIQSGSSS 1117
Query: 509 EGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQ 568
E N + + ++K+ +K + R K T SS I + Q
Sbjct: 1118 SDAEES--SEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQ 1175
Query: 569 VNVRMDSFDEDLARP---SGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSE 625
++ S DE +P + +L+ C+ S+ E +S+ + P
Sbjct: 1176 NSIGEGSSDEQKIKPVTENLVLSSHTGFCQ----SSGDEALSKSVPVTVDDDDDDNDPEN 1231
Query: 626 LFAQHIVT--IVHHVKEHHFGSSGMTLHERFTKYLKRGTEQ---EAAKNKKSPEIHRRID 680
A+ ++ I ++ GSS E + K+ E E AKN+ + E +
Sbjct: 1232 RIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSE 1291
Query: 681 ISPSTFRKHGLAHDEMK-SPREPGYKAEGKYKDDPVDLRLDIERRKKHK-------ERDL 732
S +H L ++ S E G + + K K+ +++ R + K + D
Sbjct: 1292 ESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHK-----EVKGRNRRKVSSEDSEDSDF 1346
Query: 733 KR-GKSRESVDSRDSSHSRERSAEKTE-KTHKGSKKQKKHRRARDRSRSSSSSSQSSHSY 790
+ G S E +S D R RSA+K E + ++ S KQKK RR R + + SSS S+S
Sbjct: 1347 QESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRR-RIKVQEDSSSENKSNSE 1405
Query: 791 KAEEYTEETEEREE 804
+ EE EE EE EE
Sbjct: 1406 EEEEEKEEEEEEEE 1419
Score = 48.1 bits (113), Expect = 4e-05
Identities = 161/839 (19%), Positives = 293/839 (34%), Gaps = 167/839 (19%)
Query: 3 KTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRS---------RS 53
KT K + +S++ K +S S+ +KR+ S S + +S
Sbjct: 730 KTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKS 789
Query: 54 YSPAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQN 113
S R+ +DF + + +G + + + ++ G + Q
Sbjct: 790 MSKIGAARTTKKRIPNTKDF---DSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQE 846
Query: 114 YRQAYSPRRG---------RSRSRSPKRRSPSPRSRSHSRNSDKSSSDRS---RRSSSSR 161
R+ +S G R R PK++ S + + S K S S R+ + ++
Sbjct: 847 -RETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETK 905
Query: 162 SSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSK 221
S H + ++ K+ + K + Q+ D ++ K+Q+ GT + K S+ K
Sbjct: 906 EKSKHLKTKTCKKVQDGLSDIAEKFLKKDQS--DETSEDDKKQS-KKGTEEKKKPSDFKK 962
Query: 222 PWPDATYGTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTS 281
S+S +L RE ++ + ++ K TS
Sbjct: 963 KVIKMEQQYESSS--DGTEKLPEREEICHFPKGIKQI----KNGTTDGEKKSKKIRDKTS 1016
Query: 282 QMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGG 341
+ L A + T +G S SK G+ SS+K + +S
Sbjct: 1017 KKKDELSDYA--EKSTGKGDSCDSSED-KKSKNGAYGREKKRCKLLGKSSRKRQDCSSSD 1073
Query: 342 AAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEK 401
T++Y ++ N DK K+ +E+ + + G SD+ D++K
Sbjct: 1074 ---TEKYSMKEDGCNSSDKRLKRIEL-RERRNLSSKRNTKEIQSGSSSSDAEESSEDNKK 1129
Query: 402 PFRGSQSPK---------RYKLRDDFEKKMADFHKE-----EMDDQ--------DKDKAK 439
+ + S K R LR ++K AD E DDQ D+ K K
Sbjct: 1130 KKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIK 1189
Query: 440 GRKES-----------------------------EFDDEP------KFMSKVIGANKNQE 464
E+ + D++P K + + I AN + +
Sbjct: 1190 PVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSD 1249
Query: 465 EEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVT 524
E+ S E P + K+R ++ EE E +K + + P R+
Sbjct: 1250 EDGSSDDE------PEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLL 1303
Query: 525 AYKAV-------QEKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFD 577
+K +EK + P K + R++ + S S +E+ V+ + S
Sbjct: 1304 RHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSE----DSEDSDFQESGVSEEV-SES 1358
Query: 578 EDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHH 637
ED RP A++ +L + S K++++ R I S+ +S SE
Sbjct: 1359 EDEQRPRTRSAKKAEL-EENQRSYKQKKKRRRIKVQEDSSSENKSNSE------------ 1405
Query: 638 VKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMK 697
+ E+E + ++ E D +D+ K
Sbjct: 1406 ---------------------EEEEEKEEEEEEEEEEEEEEED-----------ENDDSK 1433
Query: 698 SPREPGYKAEGKYKDDPVD------LRLDIERRKKHKERDLKRGKSRESVDSRDSSHSR 750
SP + K KDD + L+ + ERRK+ ER+ +R K RE ++ D+S ++
Sbjct: 1434 SPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTK 1492
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 79.0 bits (193), Expect = 2e-14
Identities = 161/734 (21%), Positives = 287/734 (39%), Gaps = 78/734 (10%)
Query: 113 NYRQAYSPRRGRSRSRSPKRRSPSPRSRSH-----SRNSDKSSSDRSRRSSSSRSSSNHS 167
N++ Y + + KR+ S S S +++ S + +R + S SS+ S
Sbjct: 760 NHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDS 819
Query: 168 RVES-----SKRKSAKEKKS---------SSKDSRPSQAAGDNQGDEAKEQTFSGGTSQD 213
+E SK +A+ K SS+D + S+ DNQG + +T G+S D
Sbjct: 820 ELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHK-NLKTSQEGSSDD 878
Query: 214 TKASESSKPWPDATYGTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKP 273
+ + + + A G+ + + + EL R+R P + + S V K
Sbjct: 879 AERKQERETFSSAE---GTVDKDTTIMEL--RDRLPKKQ---------QASASTDGVDK- 923
Query: 274 SPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQK 333
LS Q ++L ++ + S + + + +S+
Sbjct: 924 ---LSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSED 980
Query: 334 EESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSF 393
++ + G K+ + +K +++ + ++ EK+ E+ G ++K+ +
Sbjct: 981 DKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTT 1040
Query: 394 APKTDSEKPFRGSQSPKRYKLRDDFEKKMA--DFHKEEMDDQDKDKAKGRKESEFDDEPK 451
+ S+K R S K+ +L D EK D D + K+ A GR++ K
Sbjct: 1041 DGEKKSKK-IRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGK 1099
Query: 452 FMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEE---SFPERSKKEDRGKRS 508
K + + E+ S K +G +K+ K EL E S +K+ G S
Sbjct: 1100 SSRKRQDCSSSDTEKYSMKEDGC----NSSDKRLKRIELRERRNLSSKRNTKEIQSGSSS 1155
Query: 509 EGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQ 568
E N + + ++K+ +K + R K T SS I + Q
Sbjct: 1156 SDAEES--SEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQ 1213
Query: 569 VNVRMDSFDEDLARP---SGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSE 625
++ S DE +P + +L+ C+ S+ E +S+ + P
Sbjct: 1214 NSIGEGSSDEQKIKPVTENLVLSSHTGFCQ----SSGDEALSKSVPVTVDDDDDDNDPEN 1269
Query: 626 LFAQHIVT--IVHHVKEHHFGSSGMTLHERFTKYLKRGTEQ---EAAKNKKSPEIHRRID 680
A+ ++ I ++ GSS E + K+ E E AKN+ + E +
Sbjct: 1270 RIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSE 1329
Query: 681 ISPSTFRKHGLAHDEMK-SPREPGYKAEGKYKDDPVDLRLDIERRKKHK-------ERDL 732
S +H L ++ S E G + + K K+ +++ R + K + D
Sbjct: 1330 ESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHK-----EVKGRNRRKVSSEDSEDSDF 1384
Query: 733 KR-GKSRESVDSRDSSHSRERSAEKTE-KTHKGSKKQKKHRRARDRSRSSSSSSQSSHSY 790
+ G S E +S D R RSA+K E + ++ S KQKK RR R + + SSS S+S
Sbjct: 1385 QESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRR-RIKVQEDSSSENKSNSE 1443
Query: 791 KAEEYTEETEEREE 804
+ EE EE EE EE
Sbjct: 1444 EEEEEKEEEEEEEE 1457
Score = 48.1 bits (113), Expect = 4e-05
Identities = 161/839 (19%), Positives = 293/839 (34%), Gaps = 167/839 (19%)
Query: 3 KTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRS---------RS 53
KT K + +S++ K +S S+ +KR+ S S + +S
Sbjct: 768 KTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKS 827
Query: 54 YSPAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQN 113
S R+ +DF + + +G + + + ++ G + Q
Sbjct: 828 MSKIGAARTTKKRIPNTKDF---DSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQE 884
Query: 114 YRQAYSPRRG---------RSRSRSPKRRSPSPRSRSHSRNSDKSSSDRS---RRSSSSR 161
R+ +S G R R PK++ S + + S K S S R+ + ++
Sbjct: 885 -RETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETK 943
Query: 162 SSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSK 221
S H + ++ K+ + K + Q+ D ++ K+Q+ GT + K S+ K
Sbjct: 944 EKSKHLKTKTCKKVQDGLSDIAEKFLKKDQS--DETSEDDKKQS-KKGTEEKKKPSDFKK 1000
Query: 222 PWPDATYGTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTS 281
S+S +L RE ++ + ++ K TS
Sbjct: 1001 KVIKMEQQYESSS--DGTEKLPEREEICHFPKGIKQI----KNGTTDGEKKSKKIRDKTS 1054
Query: 282 QMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGG 341
+ L A + T +G S SK G+ SS+K + +S
Sbjct: 1055 KKKDELSDYA--EKSTGKGDSCDSSED-KKSKNGAYGREKKRCKLLGKSSRKRQDCSSSD 1111
Query: 342 AAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEK 401
T++Y ++ N DK K+ +E+ + + G SD+ D++K
Sbjct: 1112 ---TEKYSMKEDGCNSSDKRLKRIEL-RERRNLSSKRNTKEIQSGSSSSDAEESSEDNKK 1167
Query: 402 PFRGSQSPK---------RYKLRDDFEKKMADFHKE-----EMDDQ--------DKDKAK 439
+ + S K R LR ++K AD E DDQ D+ K K
Sbjct: 1168 KKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIK 1227
Query: 440 GRKES-----------------------------EFDDEP------KFMSKVIGANKNQE 464
E+ + D++P K + + I AN + +
Sbjct: 1228 PVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSD 1287
Query: 465 EEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVT 524
E+ S E P + K+R ++ EE E +K + + P R+
Sbjct: 1288 EDGSSDDE------PEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLL 1341
Query: 525 AYKAV-------QEKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITREAQVNVRMDSFD 577
+K +EK + P K + R++ + S S +E+ V+ + S
Sbjct: 1342 RHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSE----DSEDSDFQESGVSEEV-SES 1396
Query: 578 EDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHH 637
ED RP A++ +L + S K++++ R I S+ +S SE
Sbjct: 1397 EDEQRPRTRSAKKAEL-EENQRSYKQKKKRRRIKVQEDSSSENKSNSE------------ 1443
Query: 638 VKEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMK 697
+ E+E + ++ E D +D+ K
Sbjct: 1444 ---------------------EEEEEKEEEEEEEEEEEEEEED-----------ENDDSK 1471
Query: 698 SPREPGYKAEGKYKDDPVD------LRLDIERRKKHKERDLKRGKSRESVDSRDSSHSR 750
SP + K KDD + L+ + ERRK+ ER+ +R K RE ++ D+S ++
Sbjct: 1472 SPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTK 1530
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 75.9 bits (185), Expect = 2e-13
Identities = 77/207 (37%), Positives = 98/207 (47%), Gaps = 31/207 (14%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRS-----------FSKSRSRSRSLSRSRKRRLS-SRS 49
S ++ S S SR+S SRS+SRS SRS ++SRSRS S SRSR RR S SRS
Sbjct: 378 SSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRS 437
Query: 50 RSRSYSPAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRS 109
R R +S +R+ + Y R G RR R R+R + +Y RGG G
Sbjct: 438 RGRRHSGGGSRDGHR---YSRSPARRGGYGPRR----RSRSRS-HSGDRYRRGGRG---- 485
Query: 110 NWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKS-SSDRSRRSSSSRSSSNH-- 166
R S R S S SP R RSRSHS + +S S RSR S S S +
Sbjct: 486 ----LRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKL 541
Query: 167 SRVESSKRKSAKEKKSSSKDSRPSQAA 193
+R +S K KK+ + + AA
Sbjct: 542 TRPAASPAVGEKLKKTEPAAGKETGAA 568
Score = 48.5 bits (114), Expect = 3e-05
Identities = 79/330 (23%), Positives = 124/330 (37%), Gaps = 41/330 (12%)
Query: 121 RRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVES-----SKRK 175
R +R RS S S SR+ S S SS RSRR S H+R S S+ +
Sbjct: 369 RNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSR 428
Query: 176 SAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASR 235
S + +S S+ R S G G G + S S D G R
Sbjct: 429 SRRYSRSRSRGRRHS-GGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLR 487
Query: 236 ASAVSELSPRERSPALKSPLQS-VVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQ 294
+ S R RS SP +S + R RS PSP S S S+ S PS A +
Sbjct: 488 HHS----SSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRS---RSRSRSQSPSPSPAREK 540
Query: 295 SGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKT 354
+ SP+ + K+ P+ G G+++ + + K L QK
Sbjct: 541 L---------TRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQE------KLKLRMQKA 585
Query: 355 ENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKL 414
N +Q DK+ +EK + + + + + A K R + +R K
Sbjct: 586 LN------RQFKADKKAAQEKMIQQEHERQEREDELRAMARK------IRMKERERREKE 633
Query: 415 RDDFEKKMADFHKEEMDDQDKDKAKGRKES 444
R+++E++ + + ++ + R+ S
Sbjct: 634 REEWERQYSRQSRSPSPRYSREYSSSRRRS 663
Score = 43.5 bits (101), Expect = 0.001
Identities = 71/263 (26%), Positives = 96/263 (36%), Gaps = 74/263 (28%)
Query: 28 SKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQNRDFRGHNRGYRRPYYFR 87
++ RS S S S S R SSRS SRS S R
Sbjct: 373 ARRRSSSSSSSSSASRTSSSRSSSRSSS-------------------------------R 401
Query: 88 GRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSR-----------------SRSP 130
R G G Y G + RS + ++ S R RSR SRSP
Sbjct: 402 SRRGG----GYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSP 457
Query: 131 KRRSP-SPRSRSHSRNSDKSSSDRSRRS-------SSSRSSSNHSRVESSKR---KSAKE 179
RR PR RS SR+ S DR RR SSSRS S+ S S R +S
Sbjct: 458 ARRGGYGPRRRSRSRS---HSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSH 514
Query: 180 KKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAV 239
S S+ S++ + + + + + K P A TG+A
Sbjct: 515 SPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAK----- 569
Query: 240 SELSPRERSPALKSPLQSVVVRR 262
+L+P+E+ LK +Q + R+
Sbjct: 570 PKLTPQEK---LKLRMQKALNRQ 589
Score = 43.1 bits (100), Expect = 0.001
Identities = 83/413 (20%), Positives = 148/413 (35%), Gaps = 62/413 (15%)
Query: 104 YGNYRSNWQNYRQAYSPRRGRSRSRSPKR--RSPSPRSRSHSRNSDKSSSDRSRRSSS-- 159
Y RS Q R+ + +R R R SP R SP + R+ +SSS+ RS S
Sbjct: 262 YSGRRSRRQ--RREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPT 319
Query: 160 ----------SRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGG 209
+ + ++ +A ++ K P Q G G A + S
Sbjct: 320 PGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSS 379
Query: 210 TSQDTKASESSKPWPDATYGTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSP 269
+S + AS +S + S+SR+S+ RS R
Sbjct: 380 SSSSSSASRTS--------SSRSSSRSSS------------------------RSRRGGG 407
Query: 270 VPKPSPPLSSTSQMGSTLPS-GAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTY 328
+ S S+ S S Y +G+ G GS + S +SP G Y
Sbjct: 408 YYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYS---RSPARRGG-Y 463
Query: 329 GSSQKEESAASGGAAYTK--RYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDG 386
G ++ S + G Y + R L + + + + + +
Sbjct: 464 GPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRS 523
Query: 387 KMKSDSFAPKTD--SEKPFRGSQSP---KRYKLRDDFEKKMADFHKEEMDDQDKDKAKGR 441
+ +S S +P EK R + SP ++ K + K K ++ Q+K K + +
Sbjct: 524 RSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQ 583
Query: 442 K--ESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEE 492
K +F + K + + +++ +E+ + + KE++R+ +E EE
Sbjct: 584 KALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREE 636
Score = 33.9 bits (76), Expect = 0.75
Identities = 38/160 (23%), Positives = 63/160 (39%), Gaps = 8/160 (5%)
Query: 763 GSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGP 822
G ++ AR RS SSSSSS S+ + + + R G+ +S +
Sbjct: 363 GGPAPGRNASARRRS-SSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRS 421
Query: 823 SERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKYYL 882
R R+R + R+RGR +SG + + + + R + P +S+ +
Sbjct: 422 WSRSRSRSRRYSRSRSRGR-----RHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSG 476
Query: 883 HDDREGEGSDKWVSRGRGRGAF--PRGRGRFMFRKSSTSP 920
R G + S R R ++ R R + R S SP
Sbjct: 477 DRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSP 516
Score = 32.0 bits (71), Expect = 2.8
Identities = 43/211 (20%), Positives = 71/211 (33%), Gaps = 19/211 (9%)
Query: 756 KTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLG 815
+ + S A S S SSS SS S + Y + + +SR
Sbjct: 369 RNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSR 428
Query: 816 TKDFV-----GPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWD 870
++ + G GGG G R+ R G G + + + + D +R
Sbjct: 429 SRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRH 488
Query: 871 PEYTPKSKKYYLHDDREGEGSDKWVSRGRGRGAFP-RGRGRFMFRKSSTSPKWAHDKFS- 928
+ + L R + ++R R P + R R R S SP A +K +
Sbjct: 489 HSSSRSRSSWSLSPSR-----SRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTR 543
Query: 929 -------GEEGEIEDDESGTENREEKDNIQP 952
GE+ + + +G E K + P
Sbjct: 544 PAASPAVGEKLKKTEPAAGKETGAAKPKLTP 574
Score = 31.6 bits (70), Expect = 3.7
Identities = 65/262 (24%), Positives = 97/262 (37%), Gaps = 48/262 (18%)
Query: 677 RRIDISPSTFRKH--GLAHDEMKSPREP----GYKAEGKYKDDPVDLRLDIERRKKHKER 730
RR S S R+H G + D + R P GY + + R R + R
Sbjct: 430 RRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRS-----RSHSGDRYRRGGR 484
Query: 731 DLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSS------- 783
L+ S S S S SR RS ++ ++H S Q R+R RSRS S S
Sbjct: 485 GLRHHSSSRSRSSWSLSPSRSRSLTRS-RSHSPSPSQS---RSRSRSRSQSPSPSPAREK 540
Query: 784 -SQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTF--QFRARG 840
++ + S E ++TE TG K +L P E+ R + QF+A
Sbjct: 541 LTRPAASPAVGEKLKKTEPAAGKETGAAKPKL------TPQEKLKLRMQKALNRQFKADK 594
Query: 841 RGWGRGNYSGNNNNNSNND-------------FQKRNRE-EEWDPEYTPKSKKYYLHDDR 886
+ + D ++R +E EEW+ +Y+ +S+ R
Sbjct: 595 KAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSR 654
Query: 887 EGEGSDKWVSRGRGRGAFPRGR 908
E S + R R R P R
Sbjct: 655 EYSSSRR---RSRSRSRSPHYR 673
Score = 30.8 bits (68), Expect = 6.3
Identities = 17/28 (60%), Positives = 19/28 (67%)
Query: 13 SSRSRSASRSRSRSFSKSRSRSRSLSRS 40
S +SRS S SR +S SR RSRS SRS
Sbjct: 642 SRQSRSPSPRYSREYSSSRRRSRSRSRS 669
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 72.0 bits (175), Expect = 2e-12
Identities = 68/188 (36%), Positives = 87/188 (46%), Gaps = 23/188 (12%)
Query: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSK-SRSRSRSLSRSRK-----RRLSSRSRSRSYS 55
S + SKSG RS SRS+ RS S+S+ S SR R S K R +R R RSYS
Sbjct: 432 SPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYS 491
Query: 56 PAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYR 115
P R R+ P + R R PYY + G + S+ ++
Sbjct: 492 PMRKRRRDSPSHLEARRITSA-RKRPIPYYRPSPSSS----GSLSSTSSWYSSSSSRSAS 546
Query: 116 QAYSPRRGRSRSR---------SPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNH 166
++YS R RSRSR S RSPSP SRS SR+ +S RSR S SRS S+
Sbjct: 547 RSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRS---RSRSRSQSRSYSSA 603
Query: 167 SRVESSKR 174
S++R
Sbjct: 604 DSYSSTRR 611
Score = 58.9 bits (141), Expect = 2e-08
Identities = 87/374 (23%), Positives = 153/374 (40%), Gaps = 20/374 (5%)
Query: 6 KSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNR--ERN 63
K K +R R RS+S S S K + + S R+R S + R S SP R E+
Sbjct: 111 KKKKSTRKKRRRSSSYSPSPV--KKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKR 168
Query: 64 HPRVYQNRDFRGH-NRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRR 122
H + ++R + H +R +R P R ++ P +R G Q R+ +S R
Sbjct: 169 HKKQSRSRPRKSHRHRHHRCP--SRSQSSESRPSSCESR-HRGRSPEEGQKSRRRHSRRC 225
Query: 123 GRSRSR-SPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRS--SSNHSRVESSKRKSAKE 179
++ + SP+ +S P S+ S+ S S+ + S + +S+ +S +
Sbjct: 226 SKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEY 285
Query: 180 KKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAV 239
+ S PS + ++ + SGG S+ + + + ++ T S A+
Sbjct: 286 DSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAM 345
Query: 240 SE-LSPRER---SPALKSP-LQSVVVRRRSPRPSPV-PKPSPPLSSTSQMGSTLPSGAGY 293
E LSP R S +SP L+ V++ S PS P S +S ST S
Sbjct: 346 LENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSS 405
Query: 294 QSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQK 353
+S + + + S+K +SP + + S S+ S + RY ++
Sbjct: 406 RSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRE 465
Query: 354 TE---NGKDKEQKQ 364
+ + KD +Q++
Sbjct: 466 RDPKYSEKDSQQRE 479
Score = 58.5 bits (140), Expect = 3e-08
Identities = 99/477 (20%), Positives = 163/477 (34%), Gaps = 52/477 (10%)
Query: 122 RGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKK 181
RG S S K +P P SR + K S+ + RR SSS S S + + K K ++
Sbjct: 90 RGHSASHD-KDLTPPPSSR--GKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRR 146
Query: 182 SSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSE 241
S SK R S ++ ++ + K Q S + S S S S
Sbjct: 147 SFSKKRRHSSSSPKSKRRDEKRH-----KKQSRSRPRKSHRHRHHRCPSRSQSSESRPSS 201
Query: 242 LSPRERSPALKSPLQSVVVRRRSPR--------PSPVPKPSPPLSSTSQM-GSTLPSGAG 292
R R +SP + RRR R SP + S P S QM G G
Sbjct: 202 CESRHRG---RSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVI 258
Query: 293 YQSGTHQGQFDHGSGSLSPSK-------KSPVGKSPPSTGSTYGSSQKEESAASGGAAYT 345
SG+ F + L+ S+ SPPST ++ S+ +E + G
Sbjct: 259 TGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSK 318
Query: 346 KRYLEEQKTENGKDKEQKQTNTDK----------EKIKEKGSFSDTGLGDGKMKSDSFAP 395
R L T + + + +K + +E F L ++K S P
Sbjct: 319 SRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVP 378
Query: 396 KTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSK 455
T P +G Y + + ++ ++ + P + SK
Sbjct: 379 STARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSK 438
Query: 456 VIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGF 515
+ +S + P +E+ K E + + +R ++ R +R R +
Sbjct: 439 SGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQ---QRERERARRRR-----RSY 490
Query: 516 VPEKNFRVTAYKAVQ-------EKSSSPPPRKTSESRDKLGAKGDFPTGKSSFSITR 565
P + R + ++ K P R + S L + + + SS S +R
Sbjct: 491 SPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASR 547
Score = 53.9 bits (128), Expect = 7e-07
Identities = 69/244 (28%), Positives = 103/244 (42%), Gaps = 36/244 (14%)
Query: 1 MSKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSR-----------SLSRSRKRRLSSRS 49
+ K++ S +RSS + SRS S + ++S S S + SRS S S
Sbjct: 371 VKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYS 430
Query: 50 RSRSYSPAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYN-RGGYGNYR 108
RS SYS + R ++R ++R Y R R +Y+ + R
Sbjct: 431 RSPSYSSKSGKRSPPSRSSRSRRSPSYSR------YSPSRERD----PKYSEKDSQQRER 480
Query: 109 SNWQNYRQAYSPRRGRSR---SRSPKRRSPSPRSR-------SHSRNSDKSSSDRSRRSS 158
+ R++YSP R R R S RR S R R S S + SS+ SS
Sbjct: 481 ERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSS 540
Query: 159 SSRSSS---NHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTK 215
SSRS+S + SR S R+ ++ + SSS SR S + G ++ ++ S SQ
Sbjct: 541 SSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSR-SPSPGSRSRSRSRSRSRSRSRSQSRS 599
Query: 216 ASES 219
S +
Sbjct: 600 YSSA 603
Score = 48.5 bits (114), Expect = 3e-05
Identities = 88/362 (24%), Positives = 139/362 (38%), Gaps = 60/362 (16%)
Query: 3 KTNKSKSGSRSSRSRSASRSRSRSFSKSR-SRSRSLSRSRKRRLSSRSRS-RSYSPAHNR 60
++ + SG+ +S S S +RS + + S S LS+SR+ + S S S++ + +
Sbjct: 281 RSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQ 340
Query: 61 ERNHPRVYQNRDFRGH-NRGYRRPYY----------FRGRNRGFYPWGQYNRGGYGNYRS 109
+ + RG +RG++ P R G Y + RS
Sbjct: 341 NKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRS 400
Query: 110 NWQNYRQAY---SPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNH 166
+ + R SPR +SRS S ++RS S RS S+S S K S RSS SR S ++
Sbjct: 401 SSHSSRSPNPRASPRYTQSRSTSSEKRSYS-RSPSYSSKSGKRSP--PSRSSRSRRSPSY 457
Query: 167 SRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDA 226
SR S+ ++ K S KDS+ + + A+ + S
Sbjct: 458 SRYSPSRE---RDPKYSEKDSQ------QRERERARRRRRS------------------- 489
Query: 227 TYGTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTS---QM 283
Y R + S L R + A K P+ P P P S LSSTS
Sbjct: 490 -YSPMRKRRRDSPSHLEARRITSARKRPI---------PYYRPSPSSSGSLSSTSSWYSS 539
Query: 284 GSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAA 343
S+ + Y + + S + + S S SP S + S+ + S +
Sbjct: 540 SSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRS 599
Query: 344 YT 345
Y+
Sbjct: 600 YS 601
Score = 43.5 bits (101), Expect = 0.001
Identities = 109/558 (19%), Positives = 188/558 (33%), Gaps = 67/558 (12%)
Query: 333 KEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDS 392
+E A G +A + L + GK K++K T ++K + S+S + + K KS
Sbjct: 84 RELGATRGHSASHDKDLTPPPSSRGKKKKKKST---RKKRRRSSSYSPSPVKKKKKKSSK 140
Query: 393 FAPKTDS-EKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPK 451
+ S K R S S + K RD+ K + + + + + P
Sbjct: 141 KHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPS 200
Query: 452 FMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGG 511
+E +KS + + +R ++ L ++S +S + G
Sbjct: 201 SCESRHRGRSPEEGQKSRR----------RHSRRCSKTLCKDSPEAQSSRPPSQPLQMLG 250
Query: 512 H---RGFVPEKN-----FRVTAYKAVQEK-----------SSSPPPRKTSESRDKLGAKG 552
+ RG + F TA + +SSPP +TS +R + KG
Sbjct: 251 YLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKG 310
Query: 553 DFPTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIF- 611
G S + +SF + G + + ++ + F+S
Sbjct: 311 SPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSP----TSRGRESRGFQSPCL 366
Query: 612 -------QHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGTEQ 664
+ + ++ SP + ++ H S R+T+ R T
Sbjct: 367 ECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQ--SRSTSS 424
Query: 665 EAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPREPGYKAEGKYKD-DPVDLRLDIER 723
E +SP S K +S R P Y ++ DP D ++
Sbjct: 425 EKRSYSRSPSYS-------SKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQ 477
Query: 724 RKKHKERDLKRGKSRESVDSRDS-SHSRERSAEKTEKT----HKGSKKQKKHRRARDRSR 778
R++ + R +R S RDS SH R K ++ S +
Sbjct: 478 RERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWY 537
Query: 779 SSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRA 838
SSSSS +S SY + R + T S PS R+R + R+
Sbjct: 538 SSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSR------SPSPGSRSRSRSRSRSRS 591
Query: 839 RGRGWGRGNYSGNNNNNS 856
R R R +YS ++ +S
Sbjct: 592 RSRSQSR-SYSSADSYSS 608
Score = 35.8 bits (81), Expect = 0.20
Identities = 24/67 (35%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query: 734 RGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHR-RARDRSRSSSSSSQSSHSYKA 792
R SR SR S SR RS +T + R R+R RSRS S S S SY +
Sbjct: 543 RSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSS 602
Query: 793 EEYTEET 799
+ T
Sbjct: 603 ADSYSST 609
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 71.6 bits (174), Expect = 3e-12
Identities = 61/258 (23%), Positives = 110/258 (42%), Gaps = 30/258 (11%)
Query: 13 SSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQNRD 72
S +S RSRS ++S+SRS S S SR++R S+ RSRS++ + +R+++ R
Sbjct: 297 SGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK 356
Query: 73 FRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKR 132
R +R R + R+R ++R + R + + R + R R +R
Sbjct: 357 KRSKSRERR-----KSRSR------SHSRDKRKDTREKIKEKERVKEKDREKEREREKER 405
Query: 133 RSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQA 192
R ++ R+ ++ DR + R E + K ++++ K
Sbjct: 406 EKEKERGKNKDRDKER-EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEK------- 457
Query: 193 AGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPRERSPALK 252
+ + D +KE + + + P +Y SR+S+ R RS + +
Sbjct: 458 --EREKDRSKE-------IDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS-R 507
Query: 253 SPLQSVVVRRRSPR-PSP 269
SP S ++R+S R PSP
Sbjct: 508 SPRTSKTIKRKSSRSPSP 525
Score = 57.0 bits (136), Expect = 8e-08
Identities = 68/317 (21%), Positives = 122/317 (38%), Gaps = 37/317 (11%)
Query: 639 KEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKS 698
K H + H R + + + Q+ + KSP R R + D+ K
Sbjct: 321 KSHSRRKRSQSKH-RSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKD 379
Query: 699 PREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTE 758
RE + E R+ + R+K +ER+ +R K +E ++D RE+ EK +
Sbjct: 380 TREKIKEKE----------RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK 429
Query: 759 KTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKD 818
+ + +++K+H + RD+ K +E +E E ++ + D+ R K
Sbjct: 430 EKDREREREKEHEKDRDKE-------------KEKEQDKEKEREKDRSKEIDEKRKKDKK 476
Query: 819 FVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSK 878
P R R R R R + S + + ++ ++++ K K
Sbjct: 477 SRTPPRSYNASRRSRSSSRERRR---RRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 533
Query: 879 KYYLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDE 938
K D E ++ S + + R G+ K+STS K +E E D
Sbjct: 534 KREKERDHISERRERERSTSMRKSSNDRD-GKEKLEKNSTSLK-------EKEHNKEPDS 585
Query: 939 SGTENREEKDNIQPTTE 955
S ++ ++KD P TE
Sbjct: 586 SVSKEVDDKD--APRTE 600
Score = 53.9 bits (128), Expect = 7e-07
Identities = 66/267 (24%), Positives = 103/267 (38%), Gaps = 49/267 (18%)
Query: 3 KTNKSKSGSRS---SRSRSASRSRSRSFSKSRSRSRSLSRSRKR----------RLSSRS 49
K ++SK SRS SRSR R RS+S K RS+SR +SR R R +
Sbjct: 327 KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKE 386
Query: 50 RSRSYSPAHNRERNHPRVYQNRDFRGHNRGY-------RRPYYFRGRNRGFYPWGQYNRG 102
+ R +ER + + RG N+ R + R R + +R
Sbjct: 387 KERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRD 446
Query: 103 GYGNYRSNWQNYRQ----------------------AYSPRRGRSRSRSPKRRSPSPRSR 140
+ + R+ +Y+ R RSRS S +RR RS
Sbjct: 447 KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR-RSRSSSRERRRRRSRSS 505
Query: 141 SHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDE 200
S S + K+ +S RS S RS + + +R E++ + + +++ D G E
Sbjct: 506 SRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKE 565
Query: 201 AKEQTFSGGTSQDTKASESSKPWPDAT 227
E+ S K E +K PD++
Sbjct: 566 KLEK-----NSTSLKEKEHNKE-PDSS 586
Score = 51.6 bits (122), Expect = 3e-06
Identities = 64/254 (25%), Positives = 99/254 (38%), Gaps = 31/254 (12%)
Query: 724 RKKHKERDLKRGKSRESVDS-----------RDSSHSRERSAEK----TEKTHKGSKKQK 768
RK + R R KSR S S R SH+R RS +K ++ HK K +
Sbjct: 303 RKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSR 362
Query: 769 KHRRARDRSRSSSSSSQSSHSYKAEEYTEETE---ERE-ESTTGFDKSRLGTKDFVGPSE 824
+ R++R RS S + K +E +E + ERE E +K R KD E
Sbjct: 363 ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKD--RDKE 420
Query: 825 RGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKYYLHD 884
R R + + R R R + + + +++ RE++ E K KK
Sbjct: 421 REKDREKDKEKDRERER--EKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK----- 473
Query: 885 DREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSP---KWAHDKFSGEEGEIEDDESGT 941
D++ + + R + R R R R SS SP K K S ++
Sbjct: 474 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 533
Query: 942 ENREEKDNIQPTTE 955
+ +E+D+I E
Sbjct: 534 KREKERDHISERRE 547
Score = 48.1 bits (113), Expect = 4e-05
Identities = 48/224 (21%), Positives = 91/224 (40%), Gaps = 13/224 (5%)
Query: 3 KTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRER 62
+ + + G R + + R + K R R R + R + + + RE+
Sbjct: 405 REKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDR---DKEKEKEQDKEKEREK 461
Query: 63 NHPR-VYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPR 121
+ + + + R +R R Y R+R + R RS+ ++ R + + +
Sbjct: 462 DRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRS-----RSSSRSPRTSKTIK 516
Query: 122 RGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSA--KE 179
R SRS SP+ R+ + R R+ +R R +S +SS++ E ++ S KE
Sbjct: 517 RKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKE 576
Query: 180 KKSSSK-DSRPSQAAGDNQGDEAKEQTFS-GGTSQDTKASESSK 221
K+ + + DS S+ D +E G Q + + S+K
Sbjct: 577 KEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLSTK 620
Score = 47.4 bits (111), Expect = 7e-05
Identities = 44/188 (23%), Positives = 75/188 (39%), Gaps = 4/188 (2%)
Query: 735 GKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHR-RARDRSRSSSSSSQSSHSYKAE 793
GKS E R SH+R +S ++ + + Q KHR R+ +RSRS + S S +
Sbjct: 298 GKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKK 357
Query: 794 EYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNN 853
+ S + R T++ + ER + R + R + R + G N
Sbjct: 358 RSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKER--EKEKERGKNK 415
Query: 854 NNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMF 913
+ + R +++E D E + + D + + DK R + R R
Sbjct: 416 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK-EIDEKRKKD 474
Query: 914 RKSSTSPK 921
+KS T P+
Sbjct: 475 KKSRTPPR 482
Score = 47.4 bits (111), Expect = 7e-05
Identities = 62/289 (21%), Positives = 108/289 (37%), Gaps = 29/289 (10%)
Query: 308 SLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKE-QKQTN 366
S SP KK + + S S K + T+ ++E++ KD+E +++
Sbjct: 351 SKSPHKKRSKSRERRKSRSRSHSRDKRKD--------TREKIKEKERVKEKDREKERERE 402
Query: 367 TDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFH 426
++EK KE+G D D + + D + D EK + + K RD ++K D
Sbjct: 403 KEREKEKERGKNKDR---DKEREKDR---EKDKEKDREREREKEHEKDRDKEKEKEQDKE 456
Query: 427 KEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRK 486
KE D+ K+ + RK+ + P +++ E+ + P K K
Sbjct: 457 KEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIK 516
Query: 487 TEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRD 546
+ S P K+D+ + E H + E+ +E+ S RK+S RD
Sbjct: 517 RKSSRSPS-PRSRNKKDKKREKERDH---ISER----------RERERSTSMRKSSNDRD 562
Query: 547 KLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCR 595
T +E +V + D+D R Q C+
Sbjct: 563 GKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQ 611
Score = 33.1 bits (74), Expect = 1.3
Identities = 47/220 (21%), Positives = 89/220 (40%), Gaps = 23/220 (10%)
Query: 736 KSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEY 795
K E V R SA ++ K ++++ R+ RS+S SSS SHS +
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSS--KSHSRRKRSQ 330
Query: 796 TEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNN 855
++ + K R +K P ++ R++ + ++R R ++S + +
Sbjct: 331 SKHRSRSHNRSRSRQKDRRRSK---SPHKK---RSKSRERRKSRSR-----SHSRDKRKD 379
Query: 856 SNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRK 915
+ +++ R +E D E + +K + G+ D+ R + R + + R R+
Sbjct: 380 TREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREK-DKEKDRERERE 438
Query: 916 SSTSPKWAHDKFSGEEGEIEDDESGTENREEKDNIQPTTE 955
H+K +E E E D+ E EKD + E
Sbjct: 439 KE------HEKDRDKEKEKEQDK---EKEREKDRSKEIDE 469
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 71.6 bits (174), Expect = 3e-12
Identities = 61/258 (23%), Positives = 110/258 (42%), Gaps = 30/258 (11%)
Query: 13 SSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQNRD 72
S +S RSRS ++S+SRS S S SR++R S+ RSRS++ + +R+++ R
Sbjct: 181 SGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK 240
Query: 73 FRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKR 132
R +R R + R+R ++R + R + + R + R R +R
Sbjct: 241 KRSKSRERR-----KSRSR------SHSRDKRKDTREKIKEKERVKEKDREKEREREKER 289
Query: 133 RSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQA 192
R ++ R+ ++ DR + R E + K ++++ K
Sbjct: 290 EKEKERGKNKDRDKER-EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEK------- 341
Query: 193 AGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPRERSPALK 252
+ + D +KE + + + P +Y SR+S+ R RS + +
Sbjct: 342 --EREKDRSKE-------IDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS-R 391
Query: 253 SPLQSVVVRRRSPR-PSP 269
SP S ++R+S R PSP
Sbjct: 392 SPRTSKTIKRKSSRSPSP 409
Score = 57.0 bits (136), Expect = 8e-08
Identities = 68/317 (21%), Positives = 122/317 (38%), Gaps = 37/317 (11%)
Query: 639 KEHHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKS 698
K H + H R + + + Q+ + KSP R R + D+ K
Sbjct: 205 KSHSRRKRSQSKH-RSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKD 263
Query: 699 PREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTE 758
RE + E R+ + R+K +ER+ +R K +E ++D RE+ EK +
Sbjct: 264 TREKIKEKE----------RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK 313
Query: 759 KTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTKD 818
+ + +++K+H + RD+ K +E +E E ++ + D+ R K
Sbjct: 314 EKDREREREKEHEKDRDKE-------------KEKEQDKEKEREKDRSKEIDEKRKKDKK 360
Query: 819 FVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSK 878
P R R R R R + S + + ++ ++++ K K
Sbjct: 361 SRTPPRSYNASRRSRSSSRERRR---RRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 417
Query: 879 KYYLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDE 938
K D E ++ S + + R G+ K+STS K +E E D
Sbjct: 418 KREKERDHISERRERERSTSMRKSSNDRD-GKEKLEKNSTSLK-------EKEHNKEPDS 469
Query: 939 SGTENREEKDNIQPTTE 955
S ++ ++KD P TE
Sbjct: 470 SVSKEVDDKD--APRTE 484
Score = 53.9 bits (128), Expect = 7e-07
Identities = 66/267 (24%), Positives = 103/267 (38%), Gaps = 49/267 (18%)
Query: 3 KTNKSKSGSRS---SRSRSASRSRSRSFSKSRSRSRSLSRSRKR----------RLSSRS 49
K ++SK SRS SRSR R RS+S K RS+SR +SR R R +
Sbjct: 211 KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKE 270
Query: 50 RSRSYSPAHNRERNHPRVYQNRDFRGHNRGY-------RRPYYFRGRNRGFYPWGQYNRG 102
+ R +ER + + RG N+ R + R R + +R
Sbjct: 271 KERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRD 330
Query: 103 GYGNYRSNWQNYRQ----------------------AYSPRRGRSRSRSPKRRSPSPRSR 140
+ + R+ +Y+ R RSRS S +RR RS
Sbjct: 331 KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR-RSRSSSRERRRRRSRSS 389
Query: 141 SHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDE 200
S S + K+ +S RS S RS + + +R E++ + + +++ D G E
Sbjct: 390 SRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKE 449
Query: 201 AKEQTFSGGTSQDTKASESSKPWPDAT 227
E+ S K E +K PD++
Sbjct: 450 KLEK-----NSTSLKEKEHNKE-PDSS 470
Score = 51.6 bits (122), Expect = 3e-06
Identities = 64/254 (25%), Positives = 99/254 (38%), Gaps = 31/254 (12%)
Query: 724 RKKHKERDLKRGKSRESVDS-----------RDSSHSRERSAEK----TEKTHKGSKKQK 768
RK + R R KSR S S R SH+R RS +K ++ HK K +
Sbjct: 187 RKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSR 246
Query: 769 KHRRARDRSRSSSSSSQSSHSYKAEEYTEETE---ERE-ESTTGFDKSRLGTKDFVGPSE 824
+ R++R RS S + K +E +E + ERE E +K R KD E
Sbjct: 247 ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKD--RDKE 304
Query: 825 RGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKSKKYYLHD 884
R R + + R R R + + + +++ RE++ E K KK
Sbjct: 305 REKDREKDKEKDRERER--EKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK----- 357
Query: 885 DREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSP---KWAHDKFSGEEGEIEDDESGT 941
D++ + + R + R R R R SS SP K K S ++
Sbjct: 358 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 417
Query: 942 ENREEKDNIQPTTE 955
+ +E+D+I E
Sbjct: 418 KREKERDHISERRE 431
Score = 48.1 bits (113), Expect = 4e-05
Identities = 48/224 (21%), Positives = 91/224 (40%), Gaps = 13/224 (5%)
Query: 3 KTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRER 62
+ + + G R + + R + K R R R + R + + + RE+
Sbjct: 289 REKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDR---DKEKEKEQDKEKEREK 345
Query: 63 NHPR-VYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPR 121
+ + + + R +R R Y R+R + R RS+ ++ R + + +
Sbjct: 346 DRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRS-----RSSSRSPRTSKTIK 400
Query: 122 RGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSA--KE 179
R SRS SP+ R+ + R R+ +R R +S +SS++ E ++ S KE
Sbjct: 401 RKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKE 460
Query: 180 KKSSSK-DSRPSQAAGDNQGDEAKEQTFS-GGTSQDTKASESSK 221
K+ + + DS S+ D +E G Q + + S+K
Sbjct: 461 KEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLSTK 504
Score = 47.4 bits (111), Expect = 7e-05
Identities = 44/188 (23%), Positives = 75/188 (39%), Gaps = 4/188 (2%)
Query: 735 GKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHR-RARDRSRSSSSSSQSSHSYKAE 793
GKS E R SH+R +S ++ + + Q KHR R+ +RSRS + S S +
Sbjct: 182 GKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKK 241
Query: 794 EYTEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNN 853
+ S + R T++ + ER + R + R + R + G N
Sbjct: 242 RSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKER--EKEKERGKNK 299
Query: 854 NNSNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMF 913
+ + R +++E D E + + D + + DK R + R R
Sbjct: 300 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK-EIDEKRKKD 358
Query: 914 RKSSTSPK 921
+KS T P+
Sbjct: 359 KKSRTPPR 366
Score = 47.4 bits (111), Expect = 7e-05
Identities = 62/289 (21%), Positives = 108/289 (37%), Gaps = 29/289 (10%)
Query: 308 SLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKE-QKQTN 366
S SP KK + + S S K + T+ ++E++ KD+E +++
Sbjct: 235 SKSPHKKRSKSRERRKSRSRSHSRDKRKD--------TREKIKEKERVKEKDREKERERE 286
Query: 367 TDKEKIKEKGSFSDTGLGDGKMKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFH 426
++EK KE+G D D + + D + D EK + + K RD ++K D
Sbjct: 287 KEREKEKERGKNKDR---DKEREKDR---EKDKEKDREREREKEHEKDRDKEKEKEQDKE 340
Query: 427 KEEMDDQDKDKAKGRKESEFDDEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRK 486
KE D+ K+ + RK+ + P +++ E+ + P K K
Sbjct: 341 KEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIK 400
Query: 487 TEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRD 546
+ S P K+D+ + E H + E+ +E+ S RK+S RD
Sbjct: 401 RKSSRSPS-PRSRNKKDKKREKERDH---ISER----------RERERSTSMRKSSNDRD 446
Query: 547 KLGAKGDFPTGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCR 595
T +E +V + D+D R Q C+
Sbjct: 447 GKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQ 495
Score = 33.1 bits (74), Expect = 1.3
Identities = 47/220 (21%), Positives = 89/220 (40%), Gaps = 23/220 (10%)
Query: 736 KSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEY 795
K E V R SA ++ K ++++ R+ RS+S SSS SHS +
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSS--KSHSRRKRSQ 214
Query: 796 TEETEEREESTTGFDKSRLGTKDFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNN 855
++ + K R +K P ++ R++ + ++R R ++S + +
Sbjct: 215 SKHRSRSHNRSRSRQKDRRRSK---SPHKK---RSKSRERRKSRSR-----SHSRDKRKD 263
Query: 856 SNNDFQKRNREEEWDPEYTPKSKKYYLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRK 915
+ +++ R +E D E + +K + G+ D+ R + R + + R R+
Sbjct: 264 TREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREK-DKEKDRERERE 322
Query: 916 SSTSPKWAHDKFSGEEGEIEDDESGTENREEKDNIQPTTE 955
H+K +E E E D+ E EKD + E
Sbjct: 323 KE------HEKDRDKEKEKEQDK---EKEREKDRSKEIDE 353
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 71.2 bits (173), Expect = 4e-12
Identities = 64/170 (37%), Positives = 77/170 (45%), Gaps = 40/170 (23%)
Query: 6 KSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHP 65
+S+S SRSS SRS+SRS S S S+SRSRSRS S S SS+SRSRS S +R R
Sbjct: 201 RSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS-----SSQSRSRSSSRERSRSRGSK 255
Query: 66 RVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRS 125
+R RG + +R Y + SP R R
Sbjct: 256 SRSSSRSHRGSSSPRKRSY-----------------------------SSSSSSPERNRK 286
Query: 126 RSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRK 175
RSRS RS S R R +S R R SS S S + S SSK+K
Sbjct: 287 RSRS---RSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRS---SSKKK 330
Score = 65.9 bits (159), Expect = 2e-10
Identities = 57/173 (32%), Positives = 76/173 (43%), Gaps = 23/173 (13%)
Query: 13 SSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQNRD 72
S + AS + KS RSRS SRS SRS SRS SP+ +R R+ R +
Sbjct: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSS----HSRSSSRSSSPSSSRSRSRSRSRSSSS 236
Query: 73 FRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKR 132
+ +R R R R+RG RS+ +++R + SPR+ RS S
Sbjct: 237 SQSRSRSSSRE---RSRSRG------------SKSRSSSRSHRGSSSPRK---RSYSSSS 278
Query: 133 RSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSK 185
SP R+R SR+ SS DR +R + SRS R S S S K
Sbjct: 279 SSPE-RNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
Score = 62.8 bits (151), Expect = 1e-09
Identities = 60/152 (39%), Positives = 74/152 (48%), Gaps = 34/152 (22%)
Query: 2 SKTNKSKSGSRSS-----RSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSP 56
S+++ S+S SRSS RSRS SRSRS S S+SRSRS S RSR R SRS SRS+
Sbjct: 206 SRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSH-- 263
Query: 57 AHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQ 116
R + PR R ++ P R R+R RS+ R+
Sbjct: 264 ---RGSSSPRK------RSYSSSSSSPERNRKRSRS---------------RSSSSGDRK 299
Query: 117 AYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDK 148
RR RSRS + RS S S S SR+S K
Sbjct: 300 ---KRRTRSRSPERRHRSSSGSSHSGSRSSSK 328
Score = 57.8 bits (138), Expect = 5e-08
Identities = 44/115 (38%), Positives = 62/115 (53%), Gaps = 8/115 (6%)
Query: 109 SNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSR-RSSSSRSSSNHS 167
S+ ++ ++ SP RSRSRS R S S +SRS S SS +RSR R S SRSSS
Sbjct: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRS-----SSRERSRSRGSKSRSSSRSH 263
Query: 168 RVESSKRKSAKEKKSSS--KDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESS 220
R SS RK + SSS ++ + S++ + GD K +T S + ++S S
Sbjct: 264 RGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGS 318
Score = 53.1 bits (126), Expect = 1e-06
Identities = 41/121 (33%), Positives = 60/121 (49%), Gaps = 9/121 (7%)
Query: 108 RSNWQNYRQAYSPRRGRSRSR----SPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSS--- 160
RS+ ++ + S R RSRSR S R S R RS SR S SS RS R SSS
Sbjct: 212 RSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRK 271
Query: 161 RSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESS 220
RS S+ S RK ++ + SSS D + + ++ E + ++ SG + +++S
Sbjct: 272 RSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTR--SRSPERRHRSSSGSSHSGSRSSSKK 329
Query: 221 K 221
K
Sbjct: 330 K 330
Score = 48.5 bits (114), Expect = 3e-05
Identities = 30/98 (30%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Query: 125 SRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSS 184
S + RRS S SHSR+S +SSS S R S SRS S S S+ +S+ ++S S
Sbjct: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSR-SRSRSRSRSSSSSQSRSRSSSRERSRS 251
Query: 185 KDSRPSQAAGDNQGDEA-KEQTFSGGTSQDTKASESSK 221
+ S+ ++ ++G + +++++S +S + + S+
Sbjct: 252 RGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSR 289
Score = 47.4 bits (111), Expect = 7e-05
Identities = 37/125 (29%), Positives = 55/125 (44%), Gaps = 4/125 (3%)
Query: 125 SRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSS 184
S ++ + RSRS SR+S SS RS SSSRS S SR SS ++ + SS
Sbjct: 188 SEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRS-RSRSRSSSSSQSRSRSSSR 246
Query: 185 KDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSP 244
+ SR + G ++ S + + +S SS P + +S + +
Sbjct: 247 ERSR---SRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRT 303
Query: 245 RERSP 249
R RSP
Sbjct: 304 RSRSP 308
Score = 44.7 bits (104), Expect = 4e-04
Identities = 45/169 (26%), Positives = 71/169 (42%), Gaps = 14/169 (8%)
Query: 704 YKAEGKYKDDPVDL---RLDI---ERRKKHKERDLKRGKSRES---VDSRDSSHSRERSA 754
YK + +D DL LD E K K R KSR S SR SS S RS
Sbjct: 167 YKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSR 226
Query: 755 EKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRL 814
++ S + + +R+RSRS S S+SS ++ + +R S++ R
Sbjct: 227 SRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSS--RSHRGSSSPRKRSYSSSSSSPERN 284
Query: 815 GTKDFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKR 863
+ S G + R T R+R + SG++++ S + +K+
Sbjct: 285 RKRSRSRSSSSGDRKKRRT---RSRSPERRHRSSSGSSHSGSRSSSKKK 330
Score = 39.3 bits (90), Expect = 0.018
Identities = 35/145 (24%), Positives = 66/145 (45%), Gaps = 8/145 (5%)
Query: 722 ERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKTHKGSKKQKKHRRARDRSRSSS 781
E ++ ++ DL + K E D D+ S+ E+ S K+K +RR+R +SRSS
Sbjct: 154 EGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEED---SNKKKSNRRSRSKSRSSH 210
Query: 782 SSSQSSHSYKAEEYTEETEEREESTTGF-DKSRLGTKDFVGPSERGGGRARGTFQFRARG 840
S SS S + R S++ +SR +++ S G ++R + +
Sbjct: 211 SR-SSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRE---RSRSRGSKSRSSSRSHRGS 266
Query: 841 RGWGRGNYSGNNNNNSNNDFQKRNR 865
+ +YS ++++ N + R+R
Sbjct: 267 SSPRKRSYSSSSSSPERNRKRSRSR 291
Score = 33.1 bits (74), Expect = 1.3
Identities = 30/152 (19%), Positives = 61/152 (40%), Gaps = 18/152 (11%)
Query: 420 KKMADFHKE-EMDDQDKDKAKGRKESEFDDEPKFMSKV-IGANKNQEEEKS--------- 468
K++ D E E +D+D+D +K + + + D++ +SK + A++ ++ K
Sbjct: 146 KEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSK 205
Query: 469 -----GKWEGLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNFRV 523
+ +P + ++ S RS+ R + G + ++ R
Sbjct: 206 SRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRG 265
Query: 524 TA--YKAVQEKSSSPPPRKTSESRDKLGAKGD 553
++ K SSS P R SR + + GD
Sbjct: 266 SSSPRKRSYSSSSSSPERNRKRSRSRSSSSGD 297
Score = 32.7 bits (73), Expect = 1.7
Identities = 45/214 (21%), Positives = 77/214 (35%), Gaps = 6/214 (2%)
Query: 129 SPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKDSR 188
+PK R+ +++ + + R S R + R A S K+
Sbjct: 90 TPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVE 149
Query: 189 PSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGS----ASRASAVSELSP 244
++ G+ + ++ + +D ++ SK DA+ S ++R S S
Sbjct: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
Query: 245 RERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDH 304
RS + S S R RS S S SS+ + + S + S +H+G
Sbjct: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
Query: 305 GSGSLSPSKKSPV--GKSPPSTGSTYGSSQKEES 336
S S S SP K S S+ G +K +
Sbjct: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRT 303
Score = 32.0 bits (71), Expect = 2.8
Identities = 37/201 (18%), Positives = 75/201 (37%), Gaps = 20/201 (9%)
Query: 328 YGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGK 387
+G +K+ + G A + +E++++E ++E + + K K+ E D L
Sbjct: 127 FGRKKKKYRGKAVGPASILKEVEDKESEG--EEEDEDEDLSKYKLDEDEDEDDADLSKYN 184
Query: 388 MKSDSFAPKTDSEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFD 447
+ + + DS K + S R K R + + + + +++ R S
Sbjct: 185 LDASE---EEDSNK--KKSNRRSRSKSRSSHSRSSS---RSSSPSSSRSRSRSRSRSSSS 236
Query: 448 DEPKFMSKVIGANKNQEEEKSGKWEGLVYAPPGKEKQRKTEELEEESFPERSKKE----- 502
+ + S +++ + + K + G RK S PER++K
Sbjct: 237 SQSRSRS----SSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRS 292
Query: 503 -DRGKRSEGGHRGFVPEKNFR 522
G R + R PE+ R
Sbjct: 293 SSSGDRKKRRTRSRSPERRHR 313
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.123 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,004,910
Number of Sequences: 37866
Number of extensions: 2289031
Number of successful extensions: 33058
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 399
Number of HSP's successfully gapped in prelim test: 1130
Number of HSP's that attempted gapping in prelim test: 12838
Number of HSP's gapped (non-prelim): 10058
length of query: 955
length of database: 18,247,518
effective HSP length: 112
effective length of query: 843
effective length of database: 14,006,526
effective search space: 11807501418
effective search space used: 11807501418
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.