Guide to the Human Genome
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Search of human proteins with 166851804

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|166851804 tudor domain containing 9 [Homo sapiens]
         (1382 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|166851804 tudor domain containing 9 [Homo sapiens]                2761   0.0  
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ...   313   9e-85
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi...   309   1e-83
gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi...   304   4e-82
gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1...   299   1e-80
gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2...   288   2e-77
gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapi...   271   3e-72
gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 ...   267   5e-71
gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 ...   267   5e-71
gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapi...   251   4e-66
gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapi...   246   1e-64
gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]   239   1e-62
gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box po...   228   4e-59
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]    223   1e-57
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi...   221   3e-57
gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapi...   220   6e-57
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi...   211   5e-54
gi|38505213 YTH domain containing 2 [Homo sapiens]                    149   1e-35
gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi...   123   1e-27
gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Hom...   114   8e-25
gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo...    73   2e-12
gi|169163653 PREDICTED: similar to tudor domain containing 1 [Ho...    59   4e-08
gi|169164192 PREDICTED: similar to tudor domain containing 1 [Ho...    59   4e-08
gi|169163210 PREDICTED: similar to tudor domain containing 1 [Ho...    59   4e-08
gi|145312259 tudor and KH domain containing isoform a [Homo sapi...    57   1e-07
gi|145312246 tudor and KH domain containing isoform b [Homo sapi...    57   1e-07
gi|145312270 tudor and KH domain containing isoform a [Homo sapi...    57   1e-07
gi|145312256 tudor and KH domain containing isoform a [Homo sapi...    57   1e-07
gi|58197558 tudor domain containing 6 [Homo sapiens]                   56   2e-07
gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]          56   3e-07

>gi|166851804 tudor domain containing 9 [Homo sapiens]
          Length = 1382

 Score = 2761 bits (7158), Expect = 0.0
 Identities = 1382/1382 (100%), Positives = 1382/1382 (100%)

Query: 1    MLRKLTIEQINDWFTIGKTVTNVELLGAPPAFPAGAAREEVQRQDVAPGAGPAAQAPALA 60
            MLRKLTIEQINDWFTIGKTVTNVELLGAPPAFPAGAAREEVQRQDVAPGAGPAAQAPALA
Sbjct: 1    MLRKLTIEQINDWFTIGKTVTNVELLGAPPAFPAGAAREEVQRQDVAPGAGPAAQAPALA 60

Query: 61   QAPARPAAAFERSLSQRSSEVEYINKYRQLEAQELDVCRSVQPTSGPGPRPSLAKLSSVT 120
            QAPARPAAAFERSLSQRSSEVEYINKYRQLEAQELDVCRSVQPTSGPGPRPSLAKLSSVT
Sbjct: 61   QAPARPAAAFERSLSQRSSEVEYINKYRQLEAQELDVCRSVQPTSGPGPRPSLAKLSSVT 120

Query: 121  CIPGTTYKYPDLPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQRSAYC 180
            CIPGTTYKYPDLPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQRSAYC
Sbjct: 121  CIPGTTYKYPDLPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQRSAYC 180

Query: 181  SIVVTQPRKIGASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIV 240
            SIVVTQPRKIGASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIV
Sbjct: 181  SIVVTQPRKIGASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIV 240

Query: 241  SAKSLMEFTHIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFA 300
            SAKSLMEFTHIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFA
Sbjct: 241  SAKSLMEFTHIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFA 300

Query: 301  VPVQNKMNPAYIFEVEGKPHSVEEYYLNDLEHIHHSKLSPHLLEEPVITKDIYEVAVSLI 360
            VPVQNKMNPAYIFEVEGKPHSVEEYYLNDLEHIHHSKLSPHLLEEPVITKDIYEVAVSLI
Sbjct: 301  VPVQNKMNPAYIFEVEGKPHSVEEYYLNDLEHIHHSKLSPHLLEEPVITKDIYEVAVSLI 360

Query: 361  QMFDDLDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVHKRLQVYPLHS 420
            QMFDDLDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVHKRLQVYPLHS
Sbjct: 361  QMFDDLDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVHKRLQVYPLHS 420

Query: 421  SVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSL 480
            SVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSL
Sbjct: 421  SVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSL 480

Query: 481  RLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVKL 540
            RLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVKL
Sbjct: 481  RLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVKL 540

Query: 541  LDMGEPRALLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQ 600
            LDMGEPRALLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQ
Sbjct: 541  LDMGEPRALLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQ 600

Query: 601  LPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNKVNFSGSSKSD 660
            LPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNKVNFSGSSKSD
Sbjct: 601  LPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNKVNFSGSSKSD 660

Query: 661  CIALVEAFKTWKACRQTGELRYPKDELNWGRLNYIQIKRIREVAELYEELKTRISQFNMH 720
            CIALVEAFKTWKACRQTGELRYPKDELNWGRLNYIQIKRIREVAELYEELKTRISQFNMH
Sbjct: 661  CIALVEAFKTWKACRQTGELRYPKDELNWGRLNYIQIKRIREVAELYEELKTRISQFNMH 720

Query: 721  VDSRRPVMDQEYIYKQRFILQVVLAGAFYPNYFTFGQPDEEMAVRELAGKDPKTTVVLKH 780
            VDSRRPVMDQEYIYKQRFILQVVLAGAFYPNYFTFGQPDEEMAVRELAGKDPKTTVVLKH
Sbjct: 721  VDSRRPVMDQEYIYKQRFILQVVLAGAFYPNYFTFGQPDEEMAVRELAGKDPKTTVVLKH 780

Query: 781  IPPYGFLYYKQLQSLFRQCGQVKSIVFDGAKAFVEFSRNPTERFKTLPAVYMAIKMSQLK 840
            IPPYGFLYYKQLQSLFRQCGQVKSIVFDGAKAFVEFSRNPTERFKTLPAVYMAIKMSQLK
Sbjct: 781  IPPYGFLYYKQLQSLFRQCGQVKSIVFDGAKAFVEFSRNPTERFKTLPAVYMAIKMSQLK 840

Query: 841  VSLELSVHSAEEIEGKVQGMNVSKLRNTRVNVDFQKQTVDPMQVSFNTSDRSQTVTDLLL 900
            VSLELSVHSAEEIEGKVQGMNVSKLRNTRVNVDFQKQTVDPMQVSFNTSDRSQTVTDLLL
Sbjct: 841  VSLELSVHSAEEIEGKVQGMNVSKLRNTRVNVDFQKQTVDPMQVSFNTSDRSQTVTDLLL 900

Query: 901  TIDVTEVVEVGHFWGYRIDENNSEILKKLTAEINQLTLVPLPTHPHPDLVCLAPFADFDK 960
            TIDVTEVVEVGHFWGYRIDENNSEILKKLTAEINQLTLVPLPTHPHPDLVCLAPFADFDK
Sbjct: 901  TIDVTEVVEVGHFWGYRIDENNSEILKKLTAEINQLTLVPLPTHPHPDLVCLAPFADFDK 960

Query: 961  QRYFRAQVLYVSGNSAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEFKICKMRPSA 1020
            QRYFRAQVLYVSGNSAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEFKICKMRPSA
Sbjct: 961  QRYFRAQVLYVSGNSAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEFKICKMRPSA 1020

Query: 1021 KSLVCGKHWSDGASQWFASLVSGCTLLVKVFSVVHSVLHVDVYQYSGVQDAINIRDVLIQ 1080
            KSLVCGKHWSDGASQWFASLVSGCTLLVKVFSVVHSVLHVDVYQYSGVQDAINIRDVLIQ
Sbjct: 1021 KSLVCGKHWSDGASQWFASLVSGCTLLVKVFSVVHSVLHVDVYQYSGVQDAINIRDVLIQ 1080

Query: 1081 QGYAELTEESYESKQSHEVLKGLFSKSVENMTDGSVPFPMKDDEKYLIRILLESFSTNKL 1140
            QGYAELTEESYESKQSHEVLKGLFSKSVENMTDGSVPFPMKDDEKYLIRILLESFSTNKL
Sbjct: 1081 QGYAELTEESYESKQSHEVLKGLFSKSVENMTDGSVPFPMKDDEKYLIRILLESFSTNKL 1140

Query: 1141 GTPNCKAELHGPFNPYELKCHSLTRISKFRCVWIEKESINSVIISDAPEDLHQRMLVAAS 1200
            GTPNCKAELHGPFNPYELKCHSLTRISKFRCVWIEKESINSVIISDAPEDLHQRMLVAAS
Sbjct: 1141 GTPNCKAELHGPFNPYELKCHSLTRISKFRCVWIEKESINSVIISDAPEDLHQRMLVAAS 1200

Query: 1201 LSINATGSTMLLRETSLMPHIPGLPALLSMLFAPVIELRIDQNGKYYTGVLCGLGWNPAT 1260
            LSINATGSTMLLRETSLMPHIPGLPALLSMLFAPVIELRIDQNGKYYTGVLCGLGWNPAT
Sbjct: 1201 LSINATGSTMLLRETSLMPHIPGLPALLSMLFAPVIELRIDQNGKYYTGVLCGLGWNPAT 1260

Query: 1261 GASILPEHDMELAFDVQFSVEDVVEVNILRAAINKLVCDGPNGCKCLGPERVAQLQDIAR 1320
            GASILPEHDMELAFDVQFSVEDVVEVNILRAAINKLVCDGPNGCKCLGPERVAQLQDIAR
Sbjct: 1261 GASILPEHDMELAFDVQFSVEDVVEVNILRAAINKLVCDGPNGCKCLGPERVAQLQDIAR 1320

Query: 1321 QKLLGLFCQSKPREKIVPKWHEKPYEWNQVDPKLVMEQADRESSRGKNTFLYQLHKLVVL 1380
            QKLLGLFCQSKPREKIVPKWHEKPYEWNQVDPKLVMEQADRESSRGKNTFLYQLHKLVVL
Sbjct: 1321 QKLLGLFCQSKPREKIVPKWHEKPYEWNQVDPKLVMEQADRESSRGKNTFLYQLHKLVVL 1380

Query: 1381 GT 1382
            GT
Sbjct: 1381 GT 1382


>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
            sapiens]
          Length = 1386

 Score =  313 bits (801), Expect = 9e-85
 Identities = 209/652 (32%), Positives = 349/652 (53%), Gaps = 92/652 (14%)

Query: 132  LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQR--SAYCSIVVTQPRK 189
            LP    +E +++L+  + VV+I G TG GK+TQ+PQ+ILD  +        +I+ TQPR+
Sbjct: 544  LPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIICTQPRR 603

Query: 190  IGASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAKSLMEFT 249
            I A S+A  ++KERA  +G  VGYQ+ LE + +  TRL+Y TTGVLL+++    +L   +
Sbjct: 604  ISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDTALQGVS 663

Query: 250  HIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNKMNP 309
            HII+DEVHERTEE DFLLLV++ ++      ++V+LMSAT++ + F+DYF        N 
Sbjct: 664  HIIVDEVHERTEESDFLLLVLKDIVSQRPG-LQVILMSATLNAELFSDYF--------NS 714

Query: 310  AYIFEVEGKPHSVEEY------------------YLNDLEHIHHSKL------------- 338
              +  + G+   V+++                  Y+  ++ I   KL             
Sbjct: 715  CPVITIPGRTFPVDQFFLEDAIAVTRYVLQDGSPYMRSMKQISKEKLKARRNRTAFEEVE 774

Query: 339  -----SPHLLEEPVITKDIYE--------------VAVSLIQMFDDLDMKESGNKAWSGA 379
                 S HL ++  +   + +              V+ S+I+    +D ++   +     
Sbjct: 775  EDLRLSLHLQDQDSVKDAVPDQQLDFKQLLARYKGVSKSVIKTMSIMDFEKVNLELIEAL 834

Query: 380  -QFVLERS------SVLVFLPGLGEINYMHELL--TSLVHKRLQ----VYPLHSSVALEE 426
             +++++        ++LVFLPGL EI  ++E L   SL + R      ++PLHSS++ EE
Sbjct: 835  LEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEE 894

Query: 427  QNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWAS 486
            Q  VF+ P  G  KII+STNIAE+S+T+ DV YVID    +    D     +SL  ++ S
Sbjct: 895  QQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVS 954

Query: 487  KTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVKLLDMGEP 546
            + +  QRKGRAGRV+ G C+ L     +++ +    +PE+ R PL    L++K+L+M   
Sbjct: 955  QANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSA 1014

Query: 547  ---RALLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQLPV 603
               +++ +  + PP    +  + + L+++GAL            D  LT LG  LA LPV
Sbjct: 1015 HNLQSVFSRLIEPPHTDSLRASKIRLRDLGALT----------PDERLTPLGYHLASLPV 1064

Query: 604  NQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNKVNFSGSSKSDCIA 663
            + ++GKL++ G +F CLD  L IAA+L+ K+ F  P+ +  +  + K+ F+  + SD +A
Sbjct: 1065 DVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFA-FANSDYLA 1123

Query: 664  LVEAFKTWKACRQTGELRYPKDELNWGRLNYIQIKRIREVAELYEELKTRIS 715
            L++A+K W+   + G     +   N+ R N++  + ++E+A L  +    +S
Sbjct: 1124 LLQAYKGWQLSTKEG----VRASYNYCRQNFLSGRVLQEMASLKRQFTELLS 1171


>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo
           sapiens]
          Length = 1270

 Score =  309 bits (791), Expect = 1e-83
 Identities = 214/572 (37%), Positives = 307/572 (53%), Gaps = 50/572 (8%)

Query: 132 LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQ--RSAYCSIVVTQPRK 189
           LP+ +++ E++  I  NSVVII GATG GK+TQ+PQ+ILD ++Q  R+A C+IVVTQPR+
Sbjct: 388 LPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFIQNDRAAECNIVVTQPRR 447

Query: 190 IGASSIARWISKERAWTLGGVVGYQVGLEKIATED-TRLIYMTTGVLLQKIVSAKSLMEF 248
           I A S+A  ++ ER    G   GY V  E I       +++ T GVLL+K+ +   +   
Sbjct: 448 ISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKLEAG--IRGI 505

Query: 249 THIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNKMN 308
           +H+I+DE+HER    DFLL+V+R +++     V++VLMSATI    F +YF         
Sbjct: 506 SHVIVDEIHERDINTDFLLVVLRDVVQAYPE-VRIVLMSATIDTSMFCEYFF-------- 556

Query: 309 PAYIFEVEGKPHSVEEYYLNDLEHIHHSKLSPHLLEEP---------------VITKDIY 353
              I EV G+ + V+EY+L D   + H    P   ++                +I  D Y
Sbjct: 557 NCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDEY 616

Query: 354 --EVAVSLIQMFDDLDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVH- 410
             E  +S+ Q+ +     E         + +    +VLVFLPG   I  M + L    H 
Sbjct: 617 GPETRLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLEMNPHF 676

Query: 411 --KRLQVYPLHSSVALEEQNNVFLSPVP-GYRKIILSTNIAESSVTVPDVKYVIDFCLTR 467
              R Q+ PLHS +  EEQ  VF  PVP G  K+ILSTNIAE+S+T+ DV YVID C  +
Sbjct: 677 GSHRYQILPLHSQIPREEQRKVF-DPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQK 735

Query: 468 TLVCDEDTNYQSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEML 527
             +     N  +    WASKT+  QRKGRAGRV  G+C+ L  +  ++  +  H+ PEM 
Sbjct: 736 VKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFER-LETHMTPEMF 794

Query: 528 RCPLGSTILKVKLLDMGEPRALLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPH 587
           R PL    L +KLL +G     LA A+ PP L  +      L+E+ AL       D N  
Sbjct: 795 RTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDAL-------DAN-- 845

Query: 588 DGELTFLGRVLAQLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGY 647
             ELT LGR+LA+LP+  + GK++++G +F   D    IAAA      F    ++   GY
Sbjct: 846 -DELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINEGKRL--GY 902

Query: 648 RNKVNFSGSSKSDCIALVEAFKTWKACRQTGE 679
            ++ NF+G+  SD +AL+  F+ W   R  GE
Sbjct: 903 IHR-NFAGNRFSDHVALLSVFQAWDDARMGGE 933


>gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapiens]
          Length = 1369

 Score =  304 bits (778), Expect = 4e-82
 Identities = 209/683 (30%), Positives = 352/683 (51%), Gaps = 90/683 (13%)

Query: 132  LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQR---SAYCSIVVTQPR 188
            LP+ ++++ +V  ++ + VV++ G TGSGKSTQ+P ++L+  +     ++ C+IV TQPR
Sbjct: 572  LPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCNIVCTQPR 631

Query: 189  KIGASSIARWISKERAWTLG-----GVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAK 243
            +I A S+A  +  E     G      + GYQ+ +E  A E TRL+Y TTGVLL+K+    
Sbjct: 632  RISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACESTRLLYCTTGVLLRKLQEDG 691

Query: 244  SLMEFTHIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPV 303
             L   +H+I+DEVHER+ + DFLL++++++L+  S  + ++LMSAT+  ++F+ YF    
Sbjct: 692  LLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSD-LHLILMSATVDSEKFSTYFT--- 747

Query: 304  QNKMNPAYIFEVEGKPHSVEEYYLNDLEHIHHSKLSPH-------LLEEPVITKDIYEVA 356
                    I  + G+ + VE ++L D+       L          L EE  +T ++   A
Sbjct: 748  -----HCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEEEEEVTINVTSKA 802

Query: 357  VSL--------IQMFDDLDMKESGNKAWSGAQ--------------FVLE---------- 384
              +        +Q     D+     K  S  Q               +LE          
Sbjct: 803  GGIKKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILELLAYLDKSPQ 862

Query: 385  ----RSSVLVFLPGLGEINYMHELLTS---LVHKRLQVYPLHSSVALEEQNNVFLSPVPG 437
                  +VL+FLPGL  I  +++LL++      +R +V  LHS ++ ++Q   F  P PG
Sbjct: 863  FRNIEGAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQAAAFTLPPPG 922

Query: 438  YRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKTSCNQRKGRA 497
             RKI+L+TNIAE+ +T+PDV +VID   T+     E +   SL  ++ SK S  QR+GRA
Sbjct: 923  VRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRA 982

Query: 498  GRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVKLLDMGEPRALLATALSPP 557
            GRV  G+C+R+  ++ ++  + D+ VPE+LR PL    L +   ++G P   L+ AL PP
Sbjct: 983  GRVRDGFCFRMYTRERFEGFM-DYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALDPP 1041

Query: 558  GLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQLPVNQQLGKLIVLGHVF 617
             L  I   + LL+++GA  +         ++ +LT LG+ LA LPVN ++GK+++ G +F
Sbjct: 1042 QLQVISNAMNLLRKIGACEL---------NEPKLTPLGQHLAALPVNVKIGKMLIFGAIF 1092

Query: 618  GCLDECLIIAAALSLKNFFAMPFRQHLDGYRNKVNFSGS----SKSDCIALVEAFKTWKA 673
            GCLD    +AA ++ K+ F  P      G +++ + + S    + SD + +  A+  WK 
Sbjct: 1093 GCLDPVATLAAVMTEKSPFTTPI-----GRKDEADLAKSALAMADSDHLTIYNAYLGWKK 1147

Query: 674  CRQTGELRYPKDELNWGRLNYIQIKRIREVAELYEELKTRISQFNMHVDSRRPVMD---- 729
             RQ G  R    E+ + R N++    +  + ++ +EL   +        +     +    
Sbjct: 1148 ARQEGGYR---SEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRA 1204

Query: 730  -QEYIYKQRFILQVVLAGAFYPN 751
             Q   +++  +L+ VL    Y N
Sbjct: 1205 SQTLSFQEIALLKAVLVAGLYDN 1227


>gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1
           [Homo sapiens]
          Length = 1008

 Score =  299 bits (766), Expect = 1e-80
 Identities = 203/596 (34%), Positives = 318/596 (53%), Gaps = 65/596 (10%)

Query: 132 LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQRS--AYCSIVVTQPRK 189
           LP    ++E+V+LI+++ V +I G TG GK+TQ+ Q+ILD+Y++R   + C IV TQPR+
Sbjct: 207 LPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRR 266

Query: 190 IGASSIARWISKERAWTLGG--VVGYQVGLE-KIATEDTRLIYMTTGVLLQKIVSAKSLM 246
           I A S+A  ++ ERA + G     GYQ+ L+ ++  +   ++Y TTG++LQ + S   L 
Sbjct: 267 ISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYLS 326

Query: 247 EFTHIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNK 306
             +HI++DE+HER  + D L+ VV+ LL   S  +KV+LMSAT++ ++F++YF       
Sbjct: 327 SVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSD-LKVILMSATLNAEKFSEYFG------ 379

Query: 307 MNPAYIFEVEGKPHSVEEYYLNDL---------EHIHHSKLSPHLLEEPVITKD------ 351
                +  + G    V EY L D+         +  H S+     ++  V  ++      
Sbjct: 380 --NCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGHVNRQEKEEKEA 437

Query: 352 IYEV----------------AVSLIQMFDDLDMKESGNKAWSGAQFVL---ERSSVLVFL 392
           IY+                  V +I+M +D   K   N   +  ++++   E  ++LVFL
Sbjct: 438 IYKERWPDYVRELRRRYSASTVDVIEMMED--DKVDLNLIVALIRYIVLEEEDGAILVFL 495

Query: 393 PGLGEINYMHELLTSLV---HKRLQVYPLHSSVALEEQNNVFLSPVPGYRKIILSTNIAE 449
           PG   I+ +H+LL S V     +  + PLHS +    Q  VF    PG RKI+++TNIAE
Sbjct: 496 PGWDNISTLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAE 555

Query: 450 SSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKTSCNQRKGRAGRVSRGYCYRLV 509
           +S+T+ DV YVID    +    D   N  ++   W SK +  QRKGRAGRV  G+CY L 
Sbjct: 556 TSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHL- 614

Query: 510 HKDFWDNSIPDHVVPEMLRCPLGSTILKVKLLDMGEPRALLATALSPPGLSDIERTILLL 569
           +     + + D+ +PE+LR PL    L++K+L +G     L+  + PP    +  +I  L
Sbjct: 615 YNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNEAVLLSIRHL 674

Query: 570 KEVGALAVSGQREDENPHDGELTFLGRVLAQLPVNQQLGKLIVLGHVFGCLDECLIIAAA 629
            E+ AL              ELT LG  LA+LPV   +GK+I+ G +F CLD  L IAA+
Sbjct: 675 MELNAL----------DKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAAS 724

Query: 630 LSLKNFFAMPFRQHLDGYRNKVNFSGSSKSDCIALVEAFKTWKACRQTGELRYPKD 685
           LS K+ F +P  +       +   +  ++SD + +V AF+ W+  R+ G  RY KD
Sbjct: 725 LSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRG-FRYEKD 779


>gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2
           [Homo sapiens]
          Length = 994

 Score =  288 bits (738), Expect = 2e-77
 Identities = 201/593 (33%), Positives = 314/593 (52%), Gaps = 73/593 (12%)

Query: 132 LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQRS--AYCSIVVTQPRK 189
           LP    ++E+V+LI+++ V +I G TG GK+TQ+ Q+ILD+Y++R   + C IV TQPR+
Sbjct: 207 LPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRR 266

Query: 190 IGASSIARWISKERAWTLGG--VVGYQVGLE-KIATEDTRLIYMTTGVLLQKIVSAKSLM 246
           I A S+A  ++ ERA + G     GYQ+ L+ ++  +   ++Y TTG++LQ + S   L 
Sbjct: 267 ISAISVAERVAAERAESCGSGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDPYLS 326

Query: 247 EFTHIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNK 306
             +HI++DE+HER  + D L+ VV+ LL   S  +KV+LMSAT++ ++F++YF       
Sbjct: 327 SVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSD-LKVILMSATLNAEKFSEYFG------ 379

Query: 307 MNPAYIFEVEGKPHSVEEYYLNDL---------EHIHHSKLSPHLLEEPVITKD------ 351
                +  + G    V EY L D+         +  H S+     ++  V  ++      
Sbjct: 380 --NCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKRGFMQGHVNRQEKEEKEA 437

Query: 352 IYEV----------------AVSLIQMFDDLDMKESGNKAWSGAQFVL---ERSSVLVFL 392
           IY+                  V +I+M +D   K   N   +  ++++   E  ++LVFL
Sbjct: 438 IYKERWPDYVRELRRRYSASTVDVIEMMED--DKVDLNLIVALIRYIVLEEEDGAILVFL 495

Query: 393 PGLGEINYMHELLTSLVHKRLQVYPLHSSVALEEQNNVFLSPVPGYRKIILSTNIAESSV 452
           PG   I+ +H+LL S V        +  SV    Q  VF    PG RKI+++TNIAE+S+
Sbjct: 496 PGWDNISTLHDLLMSQV--------MFKSV---NQTQVFKRTPPGVRKIVIATNIAETSI 544

Query: 453 TVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKD 512
           T+ DV YVID    +    D   N  ++   W SK +  QRKGRAGRV  G+CY L +  
Sbjct: 545 TIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHL-YNG 603

Query: 513 FWDNSIPDHVVPEMLRCPLGSTILKVKLLDMGEPRALLATALSPPGLSDIERTILLLKEV 572
              + + D+ +PE+LR PL    L++K+L +G     L+  + PP    +  +I  L E+
Sbjct: 604 LRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMDPPSNEAVLLSIRHLMEL 663

Query: 573 GALAVSGQREDENPHDGELTFLGRVLAQLPVNQQLGKLIVLGHVFGCLDECLIIAAALSL 632
            AL              ELT LG  LA+LPV   +GK+I+ G +F CLD  L IAA+LS 
Sbjct: 664 NAL----------DKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSF 713

Query: 633 KNFFAMPFRQHLDGYRNKVNFSGSSKSDCIALVEAFKTWKACRQTGELRYPKD 685
           K+ F +P  +       +   +  ++SD + +V AF+ W+  R+ G  RY KD
Sbjct: 714 KDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRG-FRYEKD 765


>gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo
           sapiens]
          Length = 1143

 Score =  271 bits (693), Expect = 3e-72
 Identities = 188/603 (31%), Positives = 305/603 (50%), Gaps = 57/603 (9%)

Query: 132 LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQRSAYCSIVVTQPRKIG 191
           LPI++Y   ++  ++ + VV++ G TG GKSTQ+PQY+L      + +  +  TQPR+I 
Sbjct: 162 LPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLL-----AAGFSHVACTQPRRIA 216

Query: 192 ASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAKSLMEFTHI 251
             S+A+ +  E     G  VGYQ+  E   +  T+++++T G+LL++I    SL ++  +
Sbjct: 217 CISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPSLPQYEVL 276

Query: 252 IIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNKMNPAY 311
           I+DEVHER    DFLL V+++LL T    +KV+LMSATI+   F+ YF+         A 
Sbjct: 277 IVDEVHERHLHNDFLLGVLQRLLPTRPD-LKVILMSATINISLFSSYFS--------NAP 327

Query: 312 IFEVEGKPHSVEEYYLNDLEHIHHSKLSPHLLEEPVITKDIYEVAVSLIQMFDDLDMKES 371
           + +V G+   +   Y                  EP  +K         +++ + +D K  
Sbjct: 328 VVQVPGRLFPITVVYQPQEA-------------EPTTSKSEKLDPRPFLRVLESIDHKYP 374

Query: 372 GNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVH--KRLQVYPLHSSVALEEQNN 429
                       ER  +LVFL G+ EI+ + E   +     +R  V PLHS++++ +Q+ 
Sbjct: 375 PE----------ERGDLLVFLSGMAEISAVLEAAQTYASHTQRWVVLPLHSALSVADQDK 424

Query: 430 VFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKTS 489
           VF    PG RK ILSTNIAE+SVT+  +++V+D    + +  D     Q L+  W S+ S
Sbjct: 425 VFDVAPPGVRKCILSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQAS 484

Query: 490 CNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVKLLDMGEPRAL 549
             QRKGRAGR   G C+RL  +  +D   P + VPE+ R  L S +L++K + +G+PR  
Sbjct: 485 AEQRKGRAGRTGPGVCFRLYAESDYDAFAP-YPVPEIRRVALDSLVLQMKSMSVGDPRTF 543

Query: 550 LATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQLPVNQQLGK 609
               + PP  + +E  IL L++ GAL  S            LT +G +LAQLPV+  +GK
Sbjct: 544 --PFIEPPPPASLETAILYLRDQGALDSS----------EALTPIGSLLAQLPVDVVIGK 591

Query: 610 LIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNKVNFSGSSKSDCIALVEAFK 669
           +++LG +F  ++  L IAAALS+++ F    +   +    +     S + D   L   F 
Sbjct: 592 MLILGSMFSLVEPVLTIAAALSVQSPFTRSAQSSPECAAARRPLE-SDQGDPFTLFNVFN 650

Query: 670 TWKACRQTGELRYPKDELNWGRLNYIQIKRIREVAELYEELKTRISQFNMHVDSRRPVMD 729
            W   +        ++   W R   I+  R+ E+A L  + K  +    +   ++   + 
Sbjct: 651 AWVQVKS----ERSRNSRKWCRRRGIEEHRLYEMANLRRQFKELLEDHGLLAGAQAAQVG 706

Query: 730 QEY 732
             Y
Sbjct: 707 DSY 709


>gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2
           [Homo sapiens]
          Length = 1155

 Score =  267 bits (683), Expect = 5e-71
 Identities = 182/562 (32%), Positives = 296/562 (52%), Gaps = 65/562 (11%)

Query: 130 PDLPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQ--RSAYCSIVVTQP 187
           P LP+  +++ +++ IE + VV+I G TG GK+T++PQ +L+ YV   R A C++++TQP
Sbjct: 393 PQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQP 452

Query: 188 RKIGASSIARWISKERAWTLGGVVGYQVGLE-KIATEDTRLIYMTTGVLLQKIVSAKSLM 246
           R+I A S+A+ +S E   +L   VG+QV LE K  +    L++ T G+LL+K+ S  SL 
Sbjct: 453 RRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNPSLE 512

Query: 247 EFTHIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNK 306
             +H+I+DEVHER    DFLL++++ L R N   +++VLMSAT   + F+ YF       
Sbjct: 513 GVSHVIVDEVHERDVNTDFLLILLKGLQRLNPA-LRLVLMSATGDNERFSRYFG------ 565

Query: 307 MNPAYIFEVEGKPHSVEEYYLNDL-----------EHIHHSKLSPHLLEEPVITKDIYEV 355
                + +V G  + V+E+YL D+            H HH       L+  ++T  +  +
Sbjct: 566 --GCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHI 623

Query: 356 AVSLIQMFDDLDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLV---HKR 412
                      D +              E   +L FLPG  EI  + + L   +     +
Sbjct: 624 -----------DARG-------------EPGGILCFLPGWQEIKGVQQRLQEALGMHESK 659

Query: 413 LQVYPLHSSVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCD 472
             + P+HS++ + +Q  +F  P  G RKI+L+TNIAE+S+T+ D+ +V+D  L +    D
Sbjct: 660 YLILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYD 719

Query: 473 EDTNYQSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLG 532
             T    L   W S+ +  QR+GRAGR   G+ Y L  +   +  +P   VPE+LR PL 
Sbjct: 720 LKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVP-FQVPEILRTPLE 778

Query: 533 STILKVKLLDMGEPRAL--LATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGE 590
           + +L+ K + M E  A+  L+ A+  P +  ++  ++LL+E+G L    QRE        
Sbjct: 779 NLVLQAK-IHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVL---DQRE-------Y 827

Query: 591 LTFLGRVLAQLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNK 650
           LT LG+ LA +  + +L K IVL  +F CL   L++ + L+ ++ F+   +   +  + K
Sbjct: 828 LTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-RDPFSSSLQNRAEVDKVK 886

Query: 651 VNFSGSSKSDCIALVEAFKTWK 672
              S  S SD +A V A   W+
Sbjct: 887 ALLSHDSGSDHLAFVRAVAGWE 908


>gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1
           [Homo sapiens]
          Length = 1194

 Score =  267 bits (683), Expect = 5e-71
 Identities = 182/562 (32%), Positives = 296/562 (52%), Gaps = 65/562 (11%)

Query: 130 PDLPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQ--RSAYCSIVVTQP 187
           P LP+  +++ +++ IE + VV+I G TG GK+T++PQ +L+ YV   R A C++++TQP
Sbjct: 432 PQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQP 491

Query: 188 RKIGASSIARWISKERAWTLGGVVGYQVGLE-KIATEDTRLIYMTTGVLLQKIVSAKSLM 246
           R+I A S+A+ +S E   +L   VG+QV LE K  +    L++ T G+LL+K+ S  SL 
Sbjct: 492 RRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNPSLE 551

Query: 247 EFTHIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNK 306
             +H+I+DEVHER    DFLL++++ L R N   +++VLMSAT   + F+ YF       
Sbjct: 552 GVSHVIVDEVHERDVNTDFLLILLKGLQRLNPA-LRLVLMSATGDNERFSRYFG------ 604

Query: 307 MNPAYIFEVEGKPHSVEEYYLNDL-----------EHIHHSKLSPHLLEEPVITKDIYEV 355
                + +V G  + V+E+YL D+            H HH       L+  ++T  +  +
Sbjct: 605 --GCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHI 662

Query: 356 AVSLIQMFDDLDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLV---HKR 412
                      D +              E   +L FLPG  EI  + + L   +     +
Sbjct: 663 -----------DARG-------------EPGGILCFLPGWQEIKGVQQRLQEALGMHESK 698

Query: 413 LQVYPLHSSVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCD 472
             + P+HS++ + +Q  +F  P  G RKI+L+TNIAE+S+T+ D+ +V+D  L +    D
Sbjct: 699 YLILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYD 758

Query: 473 EDTNYQSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLG 532
             T    L   W S+ +  QR+GRAGR   G+ Y L  +   +  +P   VPE+LR PL 
Sbjct: 759 LKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVP-FQVPEILRTPLE 817

Query: 533 STILKVKLLDMGEPRAL--LATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGE 590
           + +L+ K + M E  A+  L+ A+  P +  ++  ++LL+E+G L    QRE        
Sbjct: 818 NLVLQAK-IHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVL---DQRE-------Y 866

Query: 591 LTFLGRVLAQLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNK 650
           LT LG+ LA +  + +L K IVL  +F CL   L++ + L+ ++ F+   +   +  + K
Sbjct: 867 LTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-RDPFSSSLQNRAEVDKVK 925

Query: 651 VNFSGSSKSDCIALVEAFKTWK 672
              S  S SD +A V A   W+
Sbjct: 926 ALLSHDSGSDHLAFVRAVAGWE 947


>gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo
           sapiens]
          Length = 707

 Score =  251 bits (640), Expect = 4e-66
 Identities = 187/632 (29%), Positives = 310/632 (49%), Gaps = 77/632 (12%)

Query: 106 GPGPRPSLAKLSSVTCIPGTTYKYPDLPISRYKEEVVSLIESNSVVIIHGATGSGKSTQL 165
           G   +P LA+ S+         +   LPI + + ++++ + +    ++ G TGSGK+TQ+
Sbjct: 48  GRRQQPPLAQPSASPYPEAVELQRRSLPIFQARGQLLAQLRNLDNAVLIGETGSGKTTQI 107

Query: 166 PQYILDHYVQRSAYCSIVVTQPRKIGASSIARWISKERAWTLGGVVGYQVGLEKIATEDT 225
           PQY+ +  + R     I VTQPR++ A S+A  +S E+   LG +VGY V  + + +EDT
Sbjct: 108 PQYLYEGGISRQGI--IAVTQPRRVAAISLATRVSDEKRTELGKLVGYTVRFDDVTSEDT 165

Query: 226 RLIYMTTGVLLQKIVSAKSLMEFTHIIIDEVHERTEEMDFLLLVVRKLLRTNSRF----V 281
           R+ ++T G+LL++ +S   L +++ +I+DE HERT   D L  VV+   +         +
Sbjct: 166 RIKFLTDGMLLREAISDSLLRKYSCVILDEAHERTIHTDVLFGVVKAAQKRRKELGKLPL 225

Query: 282 KVVLMSATISCKEFADYFAVPVQNKMNPAYIFEVEGKPHSVEEYYLNDLEHIHHSKLSPH 341
           KV++MSAT+    F+ YF        N A +  +EG+ H ++ +Y    ++ +       
Sbjct: 226 KVIVMSATMDVDLFSQYF--------NGAPVLYLEGRQHPIQVFYTKQPQNDY------- 270

Query: 342 LLEEPVITKDIYEVAVSLIQMFDDLDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYM 401
                     ++   VS+ Q+  +    +                 +LVFL G  EI  M
Sbjct: 271 ----------LHAALVSVFQIHQEAPSSQD----------------ILVFLTGQEEIEAM 304

Query: 402 HELLTSLVHK------RLQVYPLHSSVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVP 455
            +    +          + V PL++S+   +Q  VF     GYRK+I+STNIAE+S+T+ 
Sbjct: 305 SKTCRDIAKHLPDGCPAMLVLPLYASLPYAQQLRVFQGAPKGYRKVIISTNIAETSITIT 364

Query: 456 DVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWD 515
            +KYV+D  + +    + D+  + L +   SKT   QR GRAGR   G CYRL  +D ++
Sbjct: 365 GIKYVVDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGREDSGICYRLYTEDEFE 424

Query: 516 NSIPDHVVPEMLRCPLGSTILKVKLLDMGEPRALLATALSPPGLSDIERTILLLKEVGAL 575
                  VPE+ RC L S +L  +LL M  P  L    +S P    I+  I  L  +GAL
Sbjct: 425 -KFDKMTVPEIQRCNLASVML--QLLAMKVPNVLTFDFMSKPSPDHIQAAIAQLDLLGAL 481

Query: 576 AVSGQREDENPHDGELTFLGRVLAQLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNF 635
                ++D+      LT +GR +A  P+  +  K I++   F C +E L I + LS+ + 
Sbjct: 482 E---HKDDQL----TLTPMGRKMAAFPLEPKFAKTILMSPKFHCTEEILTIVSLLSVDSV 534

Query: 636 FAMP--FRQHLDGYRNKVNFSGSSKSDCIALVEAFKTWKACRQTGELRYPKDELNWGRLN 693
              P   R+ + G R K     SS+ D + L+  ++T+K       L   KD   W + N
Sbjct: 535 LHNPPSRREEVQGVRKKFI---SSEGDHMTLLNIYRTFK------NLGGNKD---WCKEN 582

Query: 694 YIQIKRIREVAELYEELKTRISQFNMHVDSRR 725
           ++  K +  VAE+  +L+    + +M + S R
Sbjct: 583 FVNSKNMTLVAEVRAQLRDICLKMSMPIASSR 614


>gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo
           sapiens]
          Length = 779

 Score =  246 bits (627), Expect = 1e-64
 Identities = 171/523 (32%), Positives = 276/523 (52%), Gaps = 50/523 (9%)

Query: 124 GTTYKYPDLPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQRSAYCSIV 183
           GTT   P  PI + +++++  +  NS +I+ G TGSGK+TQLP+Y+ +     S +  I 
Sbjct: 48  GTT---PTFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYE--AGFSQHGMIG 102

Query: 184 VTQPRKIGASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAK 243
           VTQPRK+ A S+A+ +++E   TLG  VGYQV  +  ++++T + YMT G LL+ I+   
Sbjct: 103 VTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDP 162

Query: 244 SLMEFTHIIIDEVHERTEEMDFLLLVVRKLLRTNS----RFVKVVLMSATISCKEFADYF 299
           +L +F+ II+DE HERT   D L  +++KL +  S      +KVV+MSAT+   + + +F
Sbjct: 163 NLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFF 222

Query: 300 AVPVQNKMNPAYIFEVEGKPHSVEEYYLNDLEHIHHSKLSPHLLEEPVITKDIYEVA--V 357
                       IF++ G+ + V E + N         + P   E     + I EV   +
Sbjct: 223 G--------NCPIFDIPGRLYPVREKFCN--------LIGPRDRENTAYIQAIVEVTMDI 266

Query: 358 SLIQMFDDLDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVHKRLQVYP 417
            L +M  D+ +  +G       QF +E+S  L+F      ++Y +++  + +   L + P
Sbjct: 267 HLNEMAGDILVFLTG-------QFEIEKSCELLFQMA-ESVDYDYDVQDTTLDGLL-ILP 317

Query: 418 LHSSVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNY 477
            + S+  ++Q  +FL P PG RK ++STNI+ +S+T+  ++YV+D    + L  +     
Sbjct: 318 CYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGL 377

Query: 478 QSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILK 537
             L +   SK+   QR GRAGR S G C+R+  KDFW+  +PDHV+PE+ R  L S +L 
Sbjct: 378 DILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLT 437

Query: 538 VKLLDMGEPRALLATALSPPGLSDIERTIL-LLKEVGALAVSGQREDENPHDGELTFLGR 596
           +K L + +   +    L PP     ER IL  LK++        + D     G +T LG 
Sbjct: 438 LKCLAIHD--VIRFPYLDPPN----ERLILEALKQL-------YQCDAIDRSGHVTRLGL 484

Query: 597 VLAQLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMP 639
            + + P+   L   ++      C D  L IAA LS++N F  P
Sbjct: 485 SMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVENVFIRP 527


>gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]
          Length = 1041

 Score =  239 bits (610), Expect = 1e-62
 Identities = 182/633 (28%), Positives = 304/633 (48%), Gaps = 97/633 (15%)

Query: 132 LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDH-YVQRSAYCSIVVTQPRKI 190
           LP+  ++EE+++ I ++ V+II G TGSGK+TQ+PQY+ +  Y  +     I  TQPR++
Sbjct: 399 LPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGM--KIACTQPRRV 456

Query: 191 GASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAKSLMEFTH 250
            A S+A  +++E    LG  VGY +  E   +E T L YMT G+LL++ +S   L  ++ 
Sbjct: 457 AAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSV 516

Query: 251 IIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNKMNPA 310
           +++DE HERT   D L  +++ + R     +KV++ SAT+    F+ +F        + A
Sbjct: 517 VMVDEAHERTLHTDILFGLIKDVARFRPE-LKVLVASATMDTARFSTFF--------DDA 567

Query: 311 YIFEVEGKPHSVEEYYLND-----LEHIHHSKLSPHLLEEPVITKDIYEVAVSLIQMFDD 365
            +F + G+   V+ +Y        LE    S L  H+ + P                   
Sbjct: 568 PVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPP------------------- 608

Query: 366 LDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVHK------RLQVYPLH 419
                                 +LVFL G  EI    E+L     +       L V P++
Sbjct: 609 --------------------GDILVFLTGQEEIEAACEMLQDPCRRLGSKIRELLVLPIY 648

Query: 420 SSVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVID--FCLTRTLVCDEDTNY 477
           +++  + Q  +F    PG RK++++TNIAE+S T+  + YV+D  FC  ++   +  T  
Sbjct: 649 ANLPSDMQARIFQPTPPGARKVVVATNIAETSPTIEGIIYVLDPGFCKQKSY--NPRTGM 706

Query: 478 QSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILK 537
           +SL ++  SK S NQR GRAGRV+ G C+RL     + + + +  VPE+ R  LG+ +L 
Sbjct: 707 ESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLL 766

Query: 538 VKLLDMGEPRALLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRV 597
           +K L + +   +    L PP    +  T+  L  +GAL           H GELT  GR 
Sbjct: 767 LKSLGIHD--LMHFDFLDPPPYETLLLTLEQLYALGAL----------NHLGELTTSGRK 814

Query: 598 LAQLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKN-FFAMPFRQHLDGYRNKVNFSGS 656
           +A+LPV+  L K+I+    + C +E L +AA LS+ N  F  P  + +     +VNF   
Sbjct: 815 MAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFF-L 873

Query: 657 SKSDCIALVEAFKTWKACRQTGELRYPKDELNWGRLNYIQIKRIREVAELYEELKTRISQ 716
              D + L+  +  W     + +         W   N++Q + +R   ++ E+L+  + +
Sbjct: 874 PGGDHLVLLNVYTQWAESGYSSQ---------WCCENFVQFRSMRRARDVREQLEGLLER 924

Query: 717 FNMHVDSRRPVMDQEYIYKQRFILQVVLAGAFY 749
             + + S       +YI     + + + AG FY
Sbjct: 925 VEVGLSS----CQGDYIR----VRKAITAGYFY 949


>gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box
           polypeptide 40 [Homo sapiens]
          Length = 452

 Score =  228 bits (580), Expect = 4e-59
 Identities = 143/424 (33%), Positives = 236/424 (55%), Gaps = 36/424 (8%)

Query: 124 GTTYKYPDLPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQRSAYCSIV 183
           GTT   P  PI + +++++  +  NS +I+ G TGSGK+TQLP+Y+ +     S +  I 
Sbjct: 48  GTT---PTFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYE--AGFSQHGMIG 102

Query: 184 VTQPRKIGASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAK 243
           VTQPRK+ A S+A+ +++E   TLG  VGYQV  +  ++++T + YMT G LL+ I+   
Sbjct: 103 VTQPRKVAAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDP 162

Query: 244 SLMEFTHIIIDEVHERTEEMDFLLLVVRKLLRTNS----RFVKVVLMSATISCKEFADYF 299
           +L +F+ II+DE HERT   D L  +++KL +  S      +KVV+MSAT+   + + +F
Sbjct: 163 NLTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFF 222

Query: 300 AVPVQNKMNPAYIFEVEGKPHSVEEYYLNDLEHIHHSKLSPHLLEEPVITKDIYEVA--V 357
                       IF++ G+ + V E + N         + P   E     + I +V   +
Sbjct: 223 G--------NCPIFDIPGRLYPVREKFCN--------LIGPRDRENTAYIQAIVKVTMDI 266

Query: 358 SLIQMFDDLDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVHKRLQVYP 417
            L +M  D+ +  +G       QF +E+S  L+F      ++Y +++  +++   L + P
Sbjct: 267 HLNEMAGDILVFLTG-------QFEIEKSCELLFQMA-ESVDYDYDVQDTILDGLL-ILP 317

Query: 418 LHSSVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNY 477
            + S+  ++Q  +FL P PG RK ++STNI+ +S+T+  ++YV+D    + L  +     
Sbjct: 318 CYGSMTTDQQRRIFLPPPPGIRKCVISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGL 377

Query: 478 QSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILK 537
             L +   SK+   QR GRAGR S G C+R+  KDFW+  +PDHV+PE+ R  L S +L 
Sbjct: 378 DILEVVPISKSEALQRSGRAGRTSSGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVLT 437

Query: 538 VKLL 541
           +K L
Sbjct: 438 LKCL 441


>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
          Length = 1220

 Score =  223 bits (568), Expect = 1e-57
 Identities = 169/591 (28%), Positives = 284/591 (48%), Gaps = 85/591 (14%)

Query: 132  LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDH-YVQRSAYCSIVVTQPRKI 190
            LPI + KE++V  +  N ++I+ G TGSGK+TQ+ QY+ +  Y  R     I  TQPR++
Sbjct: 565  LPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRG---KIGCTQPRRV 621

Query: 191  GASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAKSLMEFTH 250
             A S+A+ +S+E    LG  VGY +  E   + +T + YMT G+LL++ +    L ++  
Sbjct: 622  AAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAI 681

Query: 251  IIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNKMNPA 310
            I++DE HERT   D L  +++K ++     +K+++ SAT+   +F+ YF          A
Sbjct: 682  IMLDEAHERTIHTDVLFGLLKKTVQKRQD-MKLIVTSATLDAVKFSQYFY--------EA 732

Query: 311  YIFEVEGKPHSVEEYYLNDLE--HIHHSKLSP---HLLEEPVITKDIYEVAVSLIQMFDD 365
             IF + G+ + VE  Y  + E  ++  S ++    HL E P                   
Sbjct: 733  PIFTIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPP------------------- 773

Query: 366  LDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVHK------RLQVYPLH 419
                                  +LVFL G  EI+   E+L   +         L + P++
Sbjct: 774  --------------------GDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVY 813

Query: 420  SSVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQS 479
            S++  E Q  +F    PG RK++++TNIAE+S+T+  + YV+D    +  V +  T    
Sbjct: 814  SALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQ 873

Query: 480  LRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVK 539
            L ++  S+    QR GRAGR   G CYRL  +  + + +    VPE+ R  L ST+L +K
Sbjct: 874  LVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLK 933

Query: 540  LLDMGEPRALLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLA 599
               MG    L    +  P +  +   +  L  +GAL      +DE    G LT LGR +A
Sbjct: 934  A--MGINDLLSFDFMDAPPMETLITAMEQLYTLGAL------DDE----GLLTRLGRRMA 981

Query: 600  QLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNKVNFSGSSKS 659
            + P+   L K++++    GC +E L I + LS++N F  P  +     + K  F   ++ 
Sbjct: 982  EFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFH-QTEG 1040

Query: 660  DCIALVEAFKTWKACRQTGELRYPKDELNWGRLNYIQIKRIREVAELYEEL 710
            D + L+  + +WK  + +           W   N+IQ + +R   ++ +++
Sbjct: 1041 DHLTLLAVYNSWKNNKFSNP---------WCYENFIQARSLRRAQDIRKQM 1082


>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapiens]
          Length = 1227

 Score =  221 bits (564), Expect = 3e-57
 Identities = 171/598 (28%), Positives = 291/598 (48%), Gaps = 74/598 (12%)

Query: 132  LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQRSAYCSIVVTQPRKIG 191
            LPI   ++E++++I  NS+VI+ G TGSGK+TQL QY+  H    + Y  I  TQPR++ 
Sbjct: 532  LPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYL--HEDGYTDYGMIGCTQPRRVA 589

Query: 192  ASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAKSLMEFTHI 251
            A S+A+ +S+E    LG  VGY +  E   +E+T + YMT G+LL++ +    L  ++ I
Sbjct: 590  AMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAI 649

Query: 252  IIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFA-VPVQNKMNPA 310
            I+DE HER+   D L  ++R+++   S  +K+++ SAT+  ++FA +F  VP        
Sbjct: 650  IMDEAHERSLNTDVLFGLLREVVARRSD-LKLIVTSATMDAEKFAAFFGNVP-------- 700

Query: 311  YIFEVEGKPHSVEEYYLNDLEHIHHSKLSPHLLEEPVITKDIYEVAVSLIQMFDDLDMKE 370
             IF + G+   V+                  +L      +D  E AV           K+
Sbjct: 701  -IFHIPGRTFPVD------------------ILFSKTPQEDYVEAAV-----------KQ 730

Query: 371  SGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVHK-----RLQVYPLHSSVALE 425
            S     SGA        +L+F+PG  +I    + +   + +      L V P++S +  +
Sbjct: 731  SLQVHLSGAP-----GDILIFMPGQEDIEVTSDQIVEHLEELENAPALAVLPIYSQLPSD 785

Query: 426  EQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWA 485
             Q  +F     G RK I++TNIAE+S+TV  + +VID    +  V +      +L++   
Sbjct: 786  LQAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPI 845

Query: 486  SKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVKLLDMGE 545
            S+ + NQR GRAGR   G C+RL  +  + N +    VPE+ R  L + +L +K   +G 
Sbjct: 846  SQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLK--SLGV 903

Query: 546  PRALLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQLPVNQ 605
               L    + PP   ++  ++  L  +GAL           + G LT  GR++ + P++ 
Sbjct: 904  QDLLQFHFMDPPPEDNMLNSMYQLWILGAL----------DNTGGLTSTGRLMVEFPLDP 953

Query: 606  QLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNKVNFSGSSKSDCIALV 665
             L K++++    GC  E L+I + LS+   F  P  +  +  + +  F+   +SD +  +
Sbjct: 954  ALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFA-VPESDHLTYL 1012

Query: 666  EAFKTWKACRQTGELRYPKDELNWGRLNYIQIKRIREVAELYEELKTRISQFNMHVDS 723
              +  WK    +           W   ++I  K +R+V E+  +LK  + Q  M + S
Sbjct: 1013 NVYLQWKNNNYS---------TIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLAS 1061


>gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo
           sapiens]
          Length = 795

 Score =  220 bits (561), Expect = 6e-57
 Identities = 167/605 (27%), Positives = 290/605 (47%), Gaps = 85/605 (14%)

Query: 132 LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHY-----VQRSAYCSIVVTQ 186
           LP+  YK+    ++  +   ++ G TGSGK+TQ+PQ+ +++       +R   C    TQ
Sbjct: 137 LPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVAC----TQ 192

Query: 187 PRKIGASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAKSLM 246
           PR++ A S+A+ ++ E    LG  VGY +  E  ++  T L YMT G+LL++ ++   L 
Sbjct: 193 PRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLE 252

Query: 247 EFTHIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNK 306
            +  II+DE HERT   D L+ V+++++R  S  +KV++MSAT+   +F  YF       
Sbjct: 253 RYGVIILDEAHERTLATDILMGVLKEVVRQRSD-LKVIVMSATLDAGKFQIYF------- 304

Query: 307 MNPAYIFEVEGKPHSVEEYYLNDLEHIHHSKLSPHLLEEPVITKDIYEVAVSLIQMFDDL 366
            +   +  + G+ H VE +Y  + E                  +D  E A+  +     +
Sbjct: 305 -DNCPLLTIPGRTHPVEIFYTPEPE------------------RDYLEAAIRTVIQ---I 342

Query: 367 DMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVHKR------LQVYPLHS 420
            M E             E   +L+FL G  EI+   + +   V         +++ PL+S
Sbjct: 343 HMCEE------------EEGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYS 390

Query: 421 SVALEEQNNVFLSPVPGY------RKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDED 474
           ++  ++Q  +F  P P        RK+++STNIAE+S+T+  V +VID    +  V +  
Sbjct: 391 TLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPR 450

Query: 475 TNYQSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGST 534
              +SL ++  SK S  QR GRAGR   G C+RL  +  +   + D+  PE+LR  LGS 
Sbjct: 451 IRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSV 510

Query: 535 ILKVKLLDMGEPRALLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFL 594
           +L++K L + +   +    + PP    + R + LL  + AL            DG+LT L
Sbjct: 511 VLQLKKLGIDD--LVHFDFMDPPAPETLMRALELLNYLAAL----------NDDGDLTEL 558

Query: 595 GRVLAQLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNKVNFS 654
           G ++A+ P++ QL K+++    + C +E L I A LS+   F  P          K+ F+
Sbjct: 559 GSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPTEAKKAADEAKMRFA 618

Query: 655 GSSKSDCIALVEAFKTWKACRQTGELRYPKDELNWGRLNYIQIKRIREVAELYEELKTRI 714
                D + L+  +  +K   ++         + W   N+I  + +     + ++L   +
Sbjct: 619 -HIDGDHLTLLNVYHAFKQNHES---------VQWCYDNFINYRSLMSADNVRQQLSRIM 668

Query: 715 SQFNM 719
            +FN+
Sbjct: 669 DRFNL 673


>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo
           sapiens]
          Length = 703

 Score =  211 bits (536), Expect = 5e-54
 Identities = 182/643 (28%), Positives = 305/643 (47%), Gaps = 90/643 (13%)

Query: 104 TSGPG-----PRPSLAKLSSVTCIPGT------TYKYPDLPISRYKEEVVSLIESNSVVI 152
           T GPG      R SLA+ S  T +           +   LP+ + +  ++ LIE+   V+
Sbjct: 15  TEGPGVSISEERQSLAENSGTTVVYNPYAALSIEQQRQKLPVFKLRNHILYLIENYQTVV 74

Query: 153 IHGATGSGKSTQLPQYILDHYVQRSAYCSIV-VTQPRKIGASSIARWISKERAWTLGGVV 211
           I G TG GKSTQ+PQY+ +     +A   +V VTQPR++ A ++A  +++ER   LG  V
Sbjct: 75  IVGETGCGKSTQIPQYLAE--AGWTAEGRVVGVTQPRRVAAVTVAGRVAEERGAVLGHEV 132

Query: 212 GYQVGLEKIATE-DTRLIYMTTGVLLQKIVSAKSLMEFTHIIIDEVHERTEEMDFLLLVV 270
           GY +  +    +  TR+ ++T G+L+++++    L +++ I++DE HERT   D  + ++
Sbjct: 133 GYCIRFDDCTDQLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLL 192

Query: 271 RKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNKMN-PA----YIFEVEGKPHSVEEY 325
           +K+ +     +++++ SAT+   +F D+F    QN+ + PA     I  VEG+   V+ +
Sbjct: 193 KKIQKKRGD-LRLIVASATLDADKFRDFFN---QNETSDPARDTCVILTVEGRTFPVDIF 248

Query: 326 YLNDLEHIHHSKLSPHLLEEPVITKDIYEVAVSLIQMFDDLDMKESGNKAWSGAQFVLER 385
           YL           SP     P   K   E  V + Q   D D                  
Sbjct: 249 YLQ----------SP----VPDYIKSTVETVVKIHQTEGDGD------------------ 276

Query: 386 SSVLVFLPGLGEINYMHELLTSLVH--------KRLQVYPLHSSVALEEQNNVFLSPVPG 437
             VL FL G  E+  +  +L             + L+V P+++ +   EQ  VF      
Sbjct: 277 --VLAFLTGQEEVETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKVFERVSRS 334

Query: 438 YRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKTSCNQRKGRA 497
            RK+I++TN+AE+S+T+  + YVID    +    +  T  + L +   S+ S NQR GR 
Sbjct: 335 VRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGRG 394

Query: 498 GRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVKLLDMGEPRALLATALSPP 557
           GR   G CYRL  ++ +D  +P   VPEM R  L   IL++K L  G    L    +SPP
Sbjct: 395 GRSRSGKCYRLYTEEAFD-KLPQSTVPEMQRSNLAPVILQLKAL--GIDNVLRFHFMSPP 451

Query: 558 GLSDIERTILLLKEVGALAVSGQREDENPHDGELTF-LGRVLAQLPVNQQLGKLIVLGHV 616
               + + + LL  +G L            D  LT  LG  +A+ P+N    K+++    
Sbjct: 452 PAQSMVQALELLYALGGL----------DKDCRLTEPLGMRIAEFPLNPMFAKMLLESGN 501

Query: 617 FGCLDECLIIAAALSLKNFFAMPFRQHLDGYRNKVNFSGSSKSDCIALVEAFKTWKACRQ 676
           FGC  E L IAA + ++N F +P  Q     R    F+   + D + ++  ++ +     
Sbjct: 502 FGCSQEILSIAAMMQIQNIFVVPPNQKSHAIRVHRKFA-VEEGDHLTMLNIYEAF----- 555

Query: 677 TGELRYPKDELNWGRLNYIQIKRIREVAELYEELKTRISQFNM 719
              +++ KD   W + +++  K +   A + E+LK  + +F +
Sbjct: 556 ---IKHNKDS-KWCQEHFLNYKGLVRAATVREQLKKLLVKFQV 594


>gi|38505213 YTH domain containing 2 [Homo sapiens]
          Length = 1430

 Score =  149 bits (377), Expect = 1e-35
 Identities = 109/306 (35%), Positives = 154/306 (50%), Gaps = 23/306 (7%)

Query: 384 ERSSVLVFLPGLGEINYMHELL-------TSLVHKRLQVYPLHSSVALEEQNNVFLSPVP 436
           +  +VL+FLPG  EI  + + +           H R QV+ LHS++   +Q  V  +P  
Sbjct: 621 DAGAVLIFLPGYDEIVGLRDRILFDDKRFADNTH-RYQVFMLHSNMQTSDQKKVLKNPPA 679

Query: 437 GYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKTSCNQRKGR 496
           G RKIILSTNIAE+S+TV DV +VID    +    D       L++ W SK S  QRKGR
Sbjct: 680 GVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGR 739

Query: 497 AGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVKLL-DMGEPRA-LLATAL 554
           AGR   G C+RL  +  + N + +   PE+LR PL    L  KLL  +  P A  L  A 
Sbjct: 740 AGRCRPGICFRLFSRLRFQNML-EFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAP 798

Query: 555 SPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQLPVNQQLGKLIVLG 614
            PP    +   + +LK + A+              +LT LG  LA LPV   LGK+++  
Sbjct: 799 EPPPALIVRNAVQMLKTIDAMDTW----------EDLTELGYHLADLPVEPHLGKMVLCA 848

Query: 615 HVFGCLDECLIIAAALSLKNFFAMPFR--QHLDGYRNKVNFSGSSKSDCIALVEAFKTWK 672
            V  CLD  L IA  L+ ++ F +P +  Q       +  F+  + SD +AL+ AF+ W+
Sbjct: 849 VVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQ 908

Query: 673 ACRQTG 678
             R  G
Sbjct: 909 KARSDG 914



 Score =  139 bits (351), Expect = 1e-32
 Identities = 76/200 (38%), Positives = 118/200 (59%), Gaps = 10/200 (5%)

Query: 132 LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQRSAYCSIVVTQPRKIG 191
           LP+   +EE+V +I+ N VV+I G TGSGK+TQ+PQ++LD   +    C I  TQPR++ 
Sbjct: 193 LPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPRRLA 252

Query: 192 ASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAKS-LMEFTH 250
           A ++A  ++ ER   +G  +GYQ+ LE   +  T L + T GVLL+ +++  S L   TH
Sbjct: 253 AIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTVTH 312

Query: 251 IIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNKMNPA 310
           +I+DEVHER    DFLL  +R LL+ +   +K++L SA +    F  YF           
Sbjct: 313 VIVDEVHERDRFSDFLLTKLRDLLQKHPT-LKLILSSAALDVNLFIRYF--------GSC 363

Query: 311 YIFEVEGKPHSVEEYYLNDL 330
            +  ++G+P  V+E +L D+
Sbjct: 364 PVIYIQGRPFEVKEMFLEDI 383


>gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo
           sapiens]
          Length = 1157

 Score =  123 bits (309), Expect = 1e-27
 Identities = 100/356 (28%), Positives = 163/356 (45%), Gaps = 33/356 (9%)

Query: 413 LQVYPLHSSVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCD 472
           L V PL+S +A E+Q  VF  P  G R  +++TN+AE+S+T+P +KYV+D    +    D
Sbjct: 588 LHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYD 647

Query: 473 EDTNYQSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLG 532
             T   S R++W S+ S +QR GRAGR   G+CYRL     +         PE+ R P+ 
Sbjct: 648 RVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVF-GDFEQFPPPEITRRPVE 706

Query: 533 STILKVKLLDMGEPRALLATALSPPGLSDIERTILLLKEVGALAVSGQRE-----DENPH 587
             IL++K L++   + +     +PP +  +     LL  +GAL    + E      EN  
Sbjct: 707 DLILQMKALNV--EKVINFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRL 764

Query: 588 DGELTFLGRVLAQLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFAMPFRQHLDGY 647
              +T LGR +A  PV  +  K++ L    GCL   + I A+++++  F     + LD  
Sbjct: 765 SCPITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELF-----EELDRP 819

Query: 648 RNKVNFSGSSKSDCIALVEAFKTWK---ACRQTGEL----------RYPKDELNWGRLNY 694
                     KS    + +  +TW    A  + G+L           Y      +   N 
Sbjct: 820 AASDEELTRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCTPQFCEANG 879

Query: 695 IQIKRIREVAELYEELKTRIS----QFNMHVDSRRPVMDQEYIYKQRFILQVVLAG 746
           ++ K + E+  L  +L T ++    +  + VD   P M      +  ++ Q+V AG
Sbjct: 880 LRYKAMMEIRRLRGQLTTAVNAVCPEAELFVD---PKMQPPTESQVTYLRQIVTAG 932



 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 77/268 (28%), Positives = 132/268 (49%), Gaps = 36/268 (13%)

Query: 39  EEVQRQDVAPGAGPAAQAPALAQAPARPAAAFERSLSQRSSEVEYINKYRQLEAQELDVC 98
           EE    D  P A PA        AP  PA A                      +Q +   
Sbjct: 174 EEESELDEDPAAEPAEAGVGTTVAPLPPAPA--------------------PSSQPVPAG 213

Query: 99  RSVQPTSGPGPRPSLAKLSSVTCIPGTTYKYPD-------LPISRYKEEVVSLIESNSVV 151
            +V P     P    A       IP    + P+       LPI   ++ ++  +  + +V
Sbjct: 214 MTVPPPPAAAPPLPRALAKPAVFIP--VNRSPEMQEERLKLPILSEEQVIMEAVAEHPIV 271

Query: 152 IIHGATGSGKSTQLPQYILDHYVQRSAYCSIV-VTQPRKIGASSIARWISKERAWTLGGV 210
           I+ G TGSGK+TQ+PQ++ +     S+  SI+ VT+PR++ A ++++ ++KE   +   V
Sbjct: 272 IVCGETGSGKTTQVPQFLYE--AGFSSEDSIIGVTEPRRVAAVAMSQRVAKEMNLSQR-V 328

Query: 211 VGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAKSLMEFTHIIIDEVHERTEEMDFLLLVV 270
           V YQ+  E   TE+TR+ +MT GVLL++I     L+ +  +IIDE HER+   D L+ ++
Sbjct: 329 VSYQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLLRYKVVIIDEAHERSVYTDILIGLL 388

Query: 271 RKLLRTNSRF---VKVVLMSATISCKEF 295
            +++   ++    +K+++MSAT+  ++F
Sbjct: 389 SRIVTLRAKRNLPLKLLIMSATLRVEDF 416


>gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Homo
           sapiens]
          Length = 743

 Score =  114 bits (284), Expect = 8e-25
 Identities = 125/518 (24%), Positives = 219/518 (42%), Gaps = 69/518 (13%)

Query: 131 DLPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQ-RSAYCSIVVTQPRK 189
           DLPI + K   +  +  N +VI+ G    GKS Q+PQ+  ++ +     +  ++ TQ  K
Sbjct: 61  DLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQHGGVICTQVHK 120

Query: 190 IGASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAKSLMEFT 249
                +A  ++ E    +G  VGY +  E   T +T L Y T  +L ++++S   L  + 
Sbjct: 121 QTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYG 180

Query: 250 HIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNKMNP 309
            II+D++HER+   D LL +++ +L        ++  S  +  K  + Y  VPV      
Sbjct: 181 VIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHLISKLNSYYGNVPV------ 234

Query: 310 AYIFEVEGKPHSVEEYYLNDLEHIHHSKLSPHLLEEPVITKDIYEVAVSLIQMFDDLDMK 369
               EV+ K H VE  YL++ +                  KD +E  + LI      ++ 
Sbjct: 235 ---IEVKNK-HPVEVVYLSEAQ------------------KDSFESILRLI-----FEIH 267

Query: 370 ESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHEL----------LTSLVHKRLQVYPLH 419
            SG           E+  ++VFL    +I  + E           L  LV   + +YP  
Sbjct: 268 HSG-----------EKGDIVVFLACEQDIEKVCETVYQGSNLNPDLGELV--VVPLYPKE 314

Query: 420 SSVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQS 479
                +  +          R+++L+T+  E  +    V++VID  + R  V +      S
Sbjct: 315 KCSLFKPLDETEKRCQVYQRRVVLTTSSGEFLIWSNSVRFVIDVGVERRKVYNPRIRANS 374

Query: 480 LRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVK 539
           L +   S++    RK   G  S G  + L  ++F    +      EM    L S +L +K
Sbjct: 375 LVMQPISQSQAEIRKQILGSSSSGKFFCLYTEEFASKDMTPLKPAEMQEANLTSMVLFMK 434

Query: 540 LLDMGEPRALLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLA 599
            +D+          ++ P    + + +  L  + AL           +DG L+  G +++
Sbjct: 435 RIDIAGLGH--CDFMNRPAPESLMQALEDLDYLAAL----------DNDGNLSEFGIIMS 482

Query: 600 QLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFA 637
           + P++ QL K I+    F C+DE L IAA ++  N F+
Sbjct: 483 EFPLDPQLSKSILASCEFDCVDEVLTIAAMVTAPNCFS 520


>gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo
           sapiens]
          Length = 717

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 89/342 (26%), Positives = 140/342 (40%), Gaps = 41/342 (11%)

Query: 388 VLVFLPGLGEINYMHELLTSLVHKRL------QVYPLHSSVALEEQNNVFLSPVPGYRKI 441
           VLVFLP   EI+   E L+  V   L      +V PLH       Q    +      RK+
Sbjct: 264 VLVFLPSEEEISLCCESLSREVESLLLQGLPPRVLPLHPDCGRAVQA---VYEDMDARKV 320

Query: 442 ILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKTSCNQRKGRAGRVS 501
           +++  +A+ S ++P +++VID  L    V +     +   L   SK     R+ RA    
Sbjct: 321 VVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEARRLRARGFP 380

Query: 502 RGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVKLLDMGEPRALLATALSPPGLSD 561
            G C  L  K F +   P    P +    L S +L +K   + EP          P    
Sbjct: 381 PGSCLCLYPKSFLELEAPPLPQPRVCEENLSSLVLLLKRRQIAEPGECHFLDQPAP---- 436

Query: 562 IERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQLPVNQQLGKLIVLGHVFGCLD 621
            E  +  L+++  LA           DG+L+ LG +L++ P+  +L K ++    F C+D
Sbjct: 437 -EALMQALEDLDYLAALDD-------DGDLSDLGVILSEFPLAPELAKALLASCEFDCVD 488

Query: 622 ECLIIAAAL-SLKNFFAMPFRQHLDGYRNKVNFSGSSKSDCIALVEAF------KTWKAC 674
           E L +AA L +   F   P        R  +  +    S  I + EAF      + W  C
Sbjct: 489 EMLTLAAMLTAAPGFTRPPLSAEEAALRRALEHTDGDHSSLIQVYEAFIQSGADEAW--C 546

Query: 675 RQTGELRYPKDELNWGRLNYIQIKRIR-EVAELYEELKTRIS 715
           +  G        LNW  L   Q  ++R E+ EL + ++  +S
Sbjct: 547 QARG--------LNWAAL--CQAHKLRGELLELMQRIELPLS 578



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 52/170 (30%), Positives = 83/170 (48%), Gaps = 9/170 (5%)

Query: 106 GPGPRPSLAKLSSVTCIPGTTYKYP------DLPISRYKEEVVSLIESN--SVVIIHGAT 157
           GP P  S   ++    +P ++  Y        LPI   +   +  +ESN   VV++ G  
Sbjct: 13  GPSPGESELAVNPFDGLPFSSRYYELLKQRQALPIWAARFTFLEQLESNPTGVVLVSGEP 72

Query: 158 GSGKSTQLPQYILDHYVQRSAYCS-IVVTQPRKIGASSIARWISKERAWTLGGVVGYQVG 216
           GSGKSTQ+PQ+  +  + R      + VTQP  + A S+A  ++ E   TLG  VGY + 
Sbjct: 73  GSGKSTQIPQWCAEFALARGFQKGQVTVTQPYPLAARSLALRVADEMDLTLGHEVGYSIP 132

Query: 217 LEKIATEDTRLIYMTTGVLLQKIVSAKSLMEFTHIIIDEVHERTEEMDFL 266
            E     +T L +    +LLQ++ S +    +  +++DE  ER+   D L
Sbjct: 133 QEDCTGPNTLLRFCWDRLLLQEVASTRGTGAWGVLVLDEAQERSVASDSL 182


>gi|169163653 PREDICTED: similar to tudor domain containing 1 [Homo
            sapiens]
          Length = 2080

 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 59/248 (23%), Positives = 105/248 (42%), Gaps = 30/248 (12%)

Query: 904  VTEVVEVGHFWGYRIDENNS--EILKKLT-----AEINQLTLVPLPTHPHPDLVCLAPFA 956
            +  V+   +FW    D  N   EI+K +       E +++ L      P P L C A ++
Sbjct: 634  IAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCENDEMIL----RKPEPGLFCCARYS 689

Query: 957  DFDKQRYFRAQVLYVSGNSAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEFKICKM 1016
                +R++RA +  ++G    V+F+DYGN   +    +  +  +F ELP  A+   +  +
Sbjct: 690  K--DRRFYRAVITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAHI 747

Query: 1017 RPSAKSLVCGKHWSDGASQWFASLVSGCTLLVKVFSVVHSVLHVDVYQYSGVQDAINIRD 1076
             P          W+  A  +F  LV    +L++V +       V++ Q     + I++  
Sbjct: 748  FPVEDL------WTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNI-QSVEASENIDVIS 800

Query: 1077 VLIQQGYAELTEESYESKQSHEVLKGLFSKSVENMTDGSVPFPMKDDEKYLIRILLESFS 1136
            +++Q GYAE  +   E           F KSV   +  +     K + K +I  LLE   
Sbjct: 801  LMLQAGYAEYFQVELE----------YFPKSVSEYSMLNSESKNKVNIKKVISALLEGPK 850

Query: 1137 TNKLGTPN 1144
            + K  + N
Sbjct: 851  SKKYHSNN 858



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 49/179 (27%), Positives = 83/179 (46%), Gaps = 21/179 (11%)

Query: 920  ENNSEILKKLTAEINQL--TLVPLPTH-PHPDLVCLAPFADFDKQRYFRAQVLYVSGNSA 976
            E+  +I+K L   ++ L  TL  LP     P   CL  +   D+  + R ++  VS  S 
Sbjct: 1899 EDFFDIMKYLFMLLSDLPETLQTLPQEFIIPGSSCLFKYKSEDQ--WNRVEISEVSPQSL 1956

Query: 977  EVFFVDYGNKSHV---DLHLLMEIPCQFLELPFQALEFKICKMRPSAKSLVCGKHWSDGA 1033
             +  VDYG   ++   ++  L  +P + L LP  +    +  + P+      GKHWS+ A
Sbjct: 1957 CLVLVDYGFSFYIRYSEIINLKVVPEELLNLPRLSYPCILYGILPAK-----GKHWSEEA 2011

Query: 1034 SQWFASLVSGCTLLVKVFSVVHS--VLHVDVYQYSGVQDAINIRDVLIQQGYAELTEES 1090
              +F   +S   L+ + F   HS   L VDV     + +  N+ D+L+  G A  +++S
Sbjct: 2012 KIFFRDFLSKPDLVFQ-FREYHSETKLKVDV-----IHEKNNLADILVASGLATYSKDS 2064



 Score = 37.4 bits (85), Expect = 0.10
 Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 10/127 (7%)

Query: 900  LTIDVTEVVEVGHFWG-----YRIDENNSEILKKLTAEINQLTLVPLPTHPHPDL-VCLA 953
            + I   E V + H +       ++  NN ++    T     + L   P +    + VC++
Sbjct: 1107 IQIGSEEEVYISHIYSPQKFYCQLGRNNKDLEMIETKITESVNLQNFPKYDSNKMRVCIS 1166

Query: 954  PFADFDKQRYFRAQVLYVSGNSAEVFFVDYGNKSHVDLHLLMEIPCQFLEL---PFQALE 1010
             + + D   Y    +   S +  +V+FVD+GNK  V  ++L  I  QF EL   P QA++
Sbjct: 1167 KYVE-DGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIK 1225

Query: 1011 FKICKMR 1017
              +  +R
Sbjct: 1226 CFLSDLR 1232



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 39/172 (22%), Positives = 74/172 (43%), Gaps = 17/172 (9%)

Query: 973  GNSAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEFKICKMRPSAKSLVCGKHWSDG 1032
            GNS EV F+DYGN + V+   + E+  +FL +P   +   +  ++ +    +    W D 
Sbjct: 1516 GNSFEVEFIDYGNSAIVNTSKIYELQREFLTVPQLGIHAFLSGVKWNEPDEI----WDDK 1571

Query: 1033 ASQWFASLVSGCTLLVKVFSVVHSVLHVDVYQYSGVQDAINIRDVLIQQGYAELTEESYE 1092
               +F S V   T+  +          V++       +   I ++L  +  ++L + + +
Sbjct: 1572 TVDYFTSKVHNKTVYCEFLKKHDQKWEVNMI----CDEKCVINELLKWKACSKLQKSALQ 1627

Query: 1093 SKQ--SHEVLKG--LFSKSVENMTDGSVPFPMKDDEKYLIRILLESFSTNKL 1140
              Q  S +V  G     K   N ++GS+     +  + L +I LE F   +L
Sbjct: 1628 MPQVLSQKVRPGDNEMKKGKSNESEGSM-----NSNQQLFKIPLEEFKLGQL 1674



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 6/92 (6%)

Query: 923  SEILKKLTAEINQLTLVPLPTHPHPDLVCLAPFADFDKQRYFRAQVLYVSGNSAEVFFVD 982
            SE LK L  +I     +    +      C+A ++     ++ RA VL       ++ FVD
Sbjct: 925  SEDLKLLMEQIQNYYSIHSDPYEIGQTACVAKYSG----KWCRAAVLTQVSKEVDIVFVD 980

Query: 983  YGNKSHVDLHLLMEIPCQFLELPFQALEFKIC 1014
            YG +  V +  L  I  +FL L  QA  F+ C
Sbjct: 981  YGYQKRVLIEDLCAINPRFLLLESQA--FRCC 1010


>gi|169164192 PREDICTED: similar to tudor domain containing 1 [Homo
            sapiens]
          Length = 2080

 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 59/248 (23%), Positives = 105/248 (42%), Gaps = 30/248 (12%)

Query: 904  VTEVVEVGHFWGYRIDENNS--EILKKLT-----AEINQLTLVPLPTHPHPDLVCLAPFA 956
            +  V+   +FW    D  N   EI+K +       E +++ L      P P L C A ++
Sbjct: 634  IAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCENDEMIL----RKPEPGLFCCARYS 689

Query: 957  DFDKQRYFRAQVLYVSGNSAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEFKICKM 1016
                +R++RA +  ++G    V+F+DYGN   +    +  +  +F ELP  A+   +  +
Sbjct: 690  K--DRRFYRAVITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAHI 747

Query: 1017 RPSAKSLVCGKHWSDGASQWFASLVSGCTLLVKVFSVVHSVLHVDVYQYSGVQDAINIRD 1076
             P          W+  A  +F  LV    +L++V +       V++ Q     + I++  
Sbjct: 748  FPVEDL------WTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNI-QSVEASENIDVIS 800

Query: 1077 VLIQQGYAELTEESYESKQSHEVLKGLFSKSVENMTDGSVPFPMKDDEKYLIRILLESFS 1136
            +++Q GYAE  +   E           F KSV   +  +     K + K +I  LLE   
Sbjct: 801  LMLQAGYAEYFQVELE----------YFPKSVSEYSMLNSESKNKVNIKKVISALLEGPK 850

Query: 1137 TNKLGTPN 1144
            + K  + N
Sbjct: 851  SKKYHSNN 858



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 49/179 (27%), Positives = 83/179 (46%), Gaps = 21/179 (11%)

Query: 920  ENNSEILKKLTAEINQL--TLVPLPTH-PHPDLVCLAPFADFDKQRYFRAQVLYVSGNSA 976
            E+  +I+K L   ++ L  TL  LP     P   CL  +   D+  + R ++  VS  S 
Sbjct: 1899 EDFFDIMKYLFMLLSDLPETLQTLPQEFIIPGSSCLFKYKSEDQ--WNRVEISEVSPQSL 1956

Query: 977  EVFFVDYGNKSHV---DLHLLMEIPCQFLELPFQALEFKICKMRPSAKSLVCGKHWSDGA 1033
             +  VDYG   ++   ++  L  +P + L LP  +    +  + P+      GKHWS+ A
Sbjct: 1957 CLVLVDYGFSFYIRYSEIINLKVVPEELLNLPRLSYPCILYGILPAK-----GKHWSEEA 2011

Query: 1034 SQWFASLVSGCTLLVKVFSVVHS--VLHVDVYQYSGVQDAINIRDVLIQQGYAELTEES 1090
              +F   +S   L+ + F   HS   L VDV     + +  N+ D+L+  G A  +++S
Sbjct: 2012 KIFFRDFLSKPDLVFQ-FREYHSETKLKVDV-----IHEKNNLADILVASGLATYSKDS 2064



 Score = 37.4 bits (85), Expect = 0.10
 Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 10/127 (7%)

Query: 900  LTIDVTEVVEVGHFWG-----YRIDENNSEILKKLTAEINQLTLVPLPTHPHPDL-VCLA 953
            + I   E V + H +       ++  NN ++    T     + L   P +    + VC++
Sbjct: 1107 IQIGSEEEVYISHIYSPQKFYCQLGRNNKDLEMIETKITESVNLQNFPKYDSNKMRVCIS 1166

Query: 954  PFADFDKQRYFRAQVLYVSGNSAEVFFVDYGNKSHVDLHLLMEIPCQFLEL---PFQALE 1010
             + + D   Y    +   S +  +V+FVD+GNK  V  ++L  I  QF EL   P QA++
Sbjct: 1167 KYVE-DGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIK 1225

Query: 1011 FKICKMR 1017
              +  +R
Sbjct: 1226 CFLSDLR 1232



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 39/172 (22%), Positives = 74/172 (43%), Gaps = 17/172 (9%)

Query: 973  GNSAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEFKICKMRPSAKSLVCGKHWSDG 1032
            GNS EV F+DYGN + V+   + E+  +FL +P   +   +  ++ +    +    W D 
Sbjct: 1516 GNSFEVEFIDYGNSAIVNTSKIYELQREFLTVPQLGIHAFLSGVKWNEPDEI----WDDK 1571

Query: 1033 ASQWFASLVSGCTLLVKVFSVVHSVLHVDVYQYSGVQDAINIRDVLIQQGYAELTEESYE 1092
               +F S V   T+  +          V++       +   I ++L  +  ++L + + +
Sbjct: 1572 TVDYFTSKVHNKTVYCEFLKKHDQKWEVNMI----CDEKCVINELLKWKACSKLQKSALQ 1627

Query: 1093 SKQ--SHEVLKG--LFSKSVENMTDGSVPFPMKDDEKYLIRILLESFSTNKL 1140
              Q  S +V  G     K   N ++GS+     +  + L +I LE F   +L
Sbjct: 1628 MPQVLSQKVRPGDNEMKKGKSNESEGSM-----NSNQQLFKIPLEEFKLGQL 1674



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 6/92 (6%)

Query: 923  SEILKKLTAEINQLTLVPLPTHPHPDLVCLAPFADFDKQRYFRAQVLYVSGNSAEVFFVD 982
            SE LK L  +I     +    +      C+A ++     ++ RA VL       ++ FVD
Sbjct: 925  SEDLKLLMEQIQNYYSIHSDPYEIGQTACVAKYSG----KWCRAAVLTQVSKEVDIVFVD 980

Query: 983  YGNKSHVDLHLLMEIPCQFLELPFQALEFKIC 1014
            YG +  V +  L  I  +FL L  QA  F+ C
Sbjct: 981  YGYQKRVLIEDLCAINPRFLLLESQA--FRCC 1010


>gi|169163210 PREDICTED: similar to tudor domain containing 1 [Homo
            sapiens]
          Length = 2080

 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 59/248 (23%), Positives = 105/248 (42%), Gaps = 30/248 (12%)

Query: 904  VTEVVEVGHFWGYRIDENNS--EILKKLT-----AEINQLTLVPLPTHPHPDLVCLAPFA 956
            +  V+   +FW    D  N   EI+K +       E +++ L      P P L C A ++
Sbjct: 634  IAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCENDEMIL----RKPEPGLFCCARYS 689

Query: 957  DFDKQRYFRAQVLYVSGNSAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEFKICKM 1016
                +R++RA +  ++G    V+F+DYGN   +    +  +  +F ELP  A+   +  +
Sbjct: 690  K--DRRFYRAVITEINGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAHI 747

Query: 1017 RPSAKSLVCGKHWSDGASQWFASLVSGCTLLVKVFSVVHSVLHVDVYQYSGVQDAINIRD 1076
             P          W+  A  +F  LV    +L++V +       V++ Q     + I++  
Sbjct: 748  FPVEDL------WTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNI-QSVEASENIDVIS 800

Query: 1077 VLIQQGYAELTEESYESKQSHEVLKGLFSKSVENMTDGSVPFPMKDDEKYLIRILLESFS 1136
            +++Q GYAE  +   E           F KSV   +  +     K + K +I  LLE   
Sbjct: 801  LMLQAGYAEYFQVELE----------YFPKSVSEYSMLNSESKNKVNIKKVISALLEGPK 850

Query: 1137 TNKLGTPN 1144
            + K  + N
Sbjct: 851  SKKYHSNN 858



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 49/179 (27%), Positives = 83/179 (46%), Gaps = 21/179 (11%)

Query: 920  ENNSEILKKLTAEINQL--TLVPLPTH-PHPDLVCLAPFADFDKQRYFRAQVLYVSGNSA 976
            E+  +I+K L   ++ L  TL  LP     P   CL  +   D+  + R ++  VS  S 
Sbjct: 1899 EDFFDIMKYLFMLLSDLPETLQTLPQEFIIPGSSCLFKYKSEDQ--WNRVEISEVSPQSL 1956

Query: 977  EVFFVDYGNKSHV---DLHLLMEIPCQFLELPFQALEFKICKMRPSAKSLVCGKHWSDGA 1033
             +  VDYG   ++   ++  L  +P + L LP  +    +  + P+      GKHWS+ A
Sbjct: 1957 CLVLVDYGFSFYIRYSEIINLKVVPEELLNLPRLSYPCILYGILPAK-----GKHWSEEA 2011

Query: 1034 SQWFASLVSGCTLLVKVFSVVHS--VLHVDVYQYSGVQDAINIRDVLIQQGYAELTEES 1090
              +F   +S   L+ + F   HS   L VDV     + +  N+ D+L+  G A  +++S
Sbjct: 2012 KIFFRDFLSKPDLVFQ-FREYHSETKLKVDV-----IHEKNNLADILVASGLATYSKDS 2064



 Score = 37.4 bits (85), Expect = 0.10
 Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 10/127 (7%)

Query: 900  LTIDVTEVVEVGHFWG-----YRIDENNSEILKKLTAEINQLTLVPLPTHPHPDL-VCLA 953
            + I   E V + H +       ++  NN ++    T     + L   P +    + VC++
Sbjct: 1107 IQIGSEEEVYISHIYSPQKFYCQLGRNNKDLEMIETKITESVNLQNFPKYDSNKMRVCIS 1166

Query: 954  PFADFDKQRYFRAQVLYVSGNSAEVFFVDYGNKSHVDLHLLMEIPCQFLEL---PFQALE 1010
             + + D   Y    +   S +  +V+FVD+GNK  V  ++L  I  QF EL   P QA++
Sbjct: 1167 KYVE-DGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQFPELLFTPMQAIK 1225

Query: 1011 FKICKMR 1017
              +  +R
Sbjct: 1226 CFLSDLR 1232



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 39/172 (22%), Positives = 74/172 (43%), Gaps = 17/172 (9%)

Query: 973  GNSAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEFKICKMRPSAKSLVCGKHWSDG 1032
            GNS EV F+DYGN + V+   + E+  +FL +P   +   +  ++ +    +    W D 
Sbjct: 1516 GNSFEVEFIDYGNSAIVNTSKIYELQREFLTVPQLGIHAFLSGVKWNEPDEI----WDDK 1571

Query: 1033 ASQWFASLVSGCTLLVKVFSVVHSVLHVDVYQYSGVQDAINIRDVLIQQGYAELTEESYE 1092
               +F S V   T+  +          V++       +   I ++L  +  ++L + + +
Sbjct: 1572 TVDYFTSKVHNKTVYCEFLKKHDQKWEVNMI----CDEKCVINELLKWKACSKLQKSALQ 1627

Query: 1093 SKQ--SHEVLKG--LFSKSVENMTDGSVPFPMKDDEKYLIRILLESFSTNKL 1140
              Q  S +V  G     K   N ++GS+     +  + L +I LE F   +L
Sbjct: 1628 MPQVLSQKVRPGDNEMKKGKSNESEGSM-----NSNQQLFKIPLEEFKLGQL 1674



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 6/92 (6%)

Query: 923  SEILKKLTAEINQLTLVPLPTHPHPDLVCLAPFADFDKQRYFRAQVLYVSGNSAEVFFVD 982
            SE LK L  +I     +    +      C+A ++     ++ RA VL       ++ FVD
Sbjct: 925  SEDLKLLMEQIQNYYSIHSDPYEIGQTACVAKYSG----KWCRAAVLTQVSKEVDIVFVD 980

Query: 983  YGNKSHVDLHLLMEIPCQFLELPFQALEFKIC 1014
            YG +  V +  L  I  +FL L  QA  F+ C
Sbjct: 981  YGYQKRVLIEDLCAINPRFLLLESQA--FRCC 1010


>gi|145312259 tudor and KH domain containing isoform a [Homo sapiens]
          Length = 561

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 65/239 (27%), Positives = 108/239 (45%), Gaps = 24/239 (10%)

Query: 897  DLLLTIDVTEVVEVGHFWGYRIDENNSEILKKLTAEINQL--TLVPLPTHPHPDLVCLAP 954
            D  L + V+      HFW  +I  + S  L KL  E+ Q     VP     H   +  AP
Sbjct: 305  DEYLEVYVSASEHPNHFW-IQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAP 363

Query: 955  FADFDKQRYFRAQVLYVSGN-SAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEFKI 1013
                    ++RA+VL    N + +++FVD+G+     L  L  +   FL LPFQA+E  +
Sbjct: 364  LPT--NGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSL 421

Query: 1014 CKMRPSAKSLVCGKHWSDGASQWFASLVSGC---TLLVKVFSVVHSVLHV--DVYQY-SG 1067
             ++ PS      G  W + A   F  L        L+ K+ S V + +     +Y Y + 
Sbjct: 422  ARIAPS------GDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTS 475

Query: 1068 VQDAINIRDVLIQQGYA-ELTEESYESKQSHEVLKGLFSKSVENMTDGSVPFPMKDDEK 1125
                ++I   L+ +GYA EL E+  E++   ++LK + ++     TD S+   + + +K
Sbjct: 476  NGKKLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATE-----TDASLSTLLTETKK 529


>gi|145312246 tudor and KH domain containing isoform b [Homo sapiens]
          Length = 516

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 65/239 (27%), Positives = 108/239 (45%), Gaps = 24/239 (10%)

Query: 897  DLLLTIDVTEVVEVGHFWGYRIDENNSEILKKLTAEINQL--TLVPLPTHPHPDLVCLAP 954
            D  L + V+      HFW  +I  + S  L KL  E+ Q     VP     H   +  AP
Sbjct: 260  DEYLEVYVSASEHPNHFW-IQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAP 318

Query: 955  FADFDKQRYFRAQVLYVSGN-SAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEFKI 1013
                    ++RA+VL    N + +++FVD+G+     L  L  +   FL LPFQA+E  +
Sbjct: 319  LPT--NGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSL 376

Query: 1014 CKMRPSAKSLVCGKHWSDGASQWFASLVSGC---TLLVKVFSVVHSVLHV--DVYQY-SG 1067
             ++ PS      G  W + A   F  L        L+ K+ S V + +     +Y Y + 
Sbjct: 377  ARIAPS------GDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTS 430

Query: 1068 VQDAINIRDVLIQQGYA-ELTEESYESKQSHEVLKGLFSKSVENMTDGSVPFPMKDDEK 1125
                ++I   L+ +GYA EL E+  E++   ++LK + ++     TD S+   + + +K
Sbjct: 431  NGKKLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATE-----TDASLSTLLTETKK 484


>gi|145312270 tudor and KH domain containing isoform a [Homo sapiens]
          Length = 561

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 65/239 (27%), Positives = 108/239 (45%), Gaps = 24/239 (10%)

Query: 897  DLLLTIDVTEVVEVGHFWGYRIDENNSEILKKLTAEINQL--TLVPLPTHPHPDLVCLAP 954
            D  L + V+      HFW  +I  + S  L KL  E+ Q     VP     H   +  AP
Sbjct: 305  DEYLEVYVSASEHPNHFW-IQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAP 363

Query: 955  FADFDKQRYFRAQVLYVSGN-SAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEFKI 1013
                    ++RA+VL    N + +++FVD+G+     L  L  +   FL LPFQA+E  +
Sbjct: 364  LPT--NGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSL 421

Query: 1014 CKMRPSAKSLVCGKHWSDGASQWFASLVSGC---TLLVKVFSVVHSVLHV--DVYQY-SG 1067
             ++ PS      G  W + A   F  L        L+ K+ S V + +     +Y Y + 
Sbjct: 422  ARIAPS------GDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTS 475

Query: 1068 VQDAINIRDVLIQQGYA-ELTEESYESKQSHEVLKGLFSKSVENMTDGSVPFPMKDDEK 1125
                ++I   L+ +GYA EL E+  E++   ++LK + ++     TD S+   + + +K
Sbjct: 476  NGKKLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATE-----TDASLSTLLTETKK 529


>gi|145312256 tudor and KH domain containing isoform a [Homo sapiens]
          Length = 561

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 65/239 (27%), Positives = 108/239 (45%), Gaps = 24/239 (10%)

Query: 897  DLLLTIDVTEVVEVGHFWGYRIDENNSEILKKLTAEINQL--TLVPLPTHPHPDLVCLAP 954
            D  L + V+      HFW  +I  + S  L KL  E+ Q     VP     H   +  AP
Sbjct: 305  DEYLEVYVSASEHPNHFW-IQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAP 363

Query: 955  FADFDKQRYFRAQVLYVSGN-SAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEFKI 1013
                    ++RA+VL    N + +++FVD+G+     L  L  +   FL LPFQA+E  +
Sbjct: 364  LPT--NGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSL 421

Query: 1014 CKMRPSAKSLVCGKHWSDGASQWFASLVSGC---TLLVKVFSVVHSVLHV--DVYQY-SG 1067
             ++ PS      G  W + A   F  L        L+ K+ S V + +     +Y Y + 
Sbjct: 422  ARIAPS------GDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTS 475

Query: 1068 VQDAINIRDVLIQQGYA-ELTEESYESKQSHEVLKGLFSKSVENMTDGSVPFPMKDDEK 1125
                ++I   L+ +GYA EL E+  E++   ++LK + ++     TD S+   + + +K
Sbjct: 476  NGKKLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATE-----TDASLSTLLTETKK 529


>gi|58197558 tudor domain containing 6 [Homo sapiens]
          Length = 2096

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 42/152 (27%), Positives = 71/152 (46%), Gaps = 12/152 (7%)

Query: 945  PHPDLVCLAPFADFDKQRYFRAQVLYVSGNSAEVFFVDYGNKSHVDLHLLMEIPCQFLEL 1004
            P PD +C   + +     Y+RA V  +   S +VF VD GN  +VD + +  +  QF +L
Sbjct: 537  PEPDDLCCVKWKE---NGYYRAIVTKLDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQL 593

Query: 1005 PFQALEFKICKMRPSAKSLVCGKHWSDGASQWFASLVSGCTLLVKVFSVVHSVLHVDVYQ 1064
            P  A++  +  + P       GK WS  A  +F   V    L++ +         +++  
Sbjct: 594  PILAVKCTLADIWP------LGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIEILD 647

Query: 1065 YSGVQDAINIRDVLIQQGYAELTEESYESKQS 1096
             S   +  NI  V+ Q GYA+  E  +E+K++
Sbjct: 648  ESRTGEE-NISKVIAQAGYAKYQE--FETKEN 676



 Score = 40.4 bits (93), Expect = 0.012
 Identities = 34/94 (36%), Positives = 51/94 (54%), Gaps = 11/94 (11%)

Query: 922  NSEILKKLTAEINQLT--LVPLPTHP-HPDLVCLAPFADFDKQRYFRAQVLYVSGNSAEV 978
            N+ IL++L+  I QL+  L+ L T P +P  +CLA + D +   ++R  V  +     +V
Sbjct: 1008 NANILEQLSCSITQLSKVLLNLKTSPLNPGTLCLAKYTDGN---WYRGIV--IEKEPKKV 1062

Query: 979  FFVDYGNKSHVDLHLLMEIPC---QFLELPFQAL 1009
            FFVD+GN   V    L+ IP      L LP QA+
Sbjct: 1063 FFVDFGNIYVVTSDDLLPIPSDAYDVLLLPMQAV 1096



 Score = 34.7 bits (78), Expect = 0.65
 Identities = 31/128 (24%), Positives = 56/128 (43%), Gaps = 5/128 (3%)

Query: 882  MQVSFNTSDRSQTVTDLLLTIDVTEVVEVGHFWGYRIDENNSEILKKLTAEINQLTLVPL 941
            +++   +S + +      + + V+ V   G+FW       N + LK L ++I        
Sbjct: 756  LEIKPGSSSKGELEVGSTVEVRVSYVENPGYFWCQLT--RNIQGLKTLMSDIQYYCKNTA 813

Query: 942  PTHPHPDLVCLAPFADFDKQRYFRAQVLYV-SGNSAEVFFVDYGNKSHVDLHLLMEIPCQ 1000
              H    L CLA       +++ RA +  + S     V FVDYG++  V +  +  I  +
Sbjct: 814  APHQRNTLACLAKRTV--NRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEE 871

Query: 1001 FLELPFQA 1008
            FL++  QA
Sbjct: 872  FLKVKAQA 879


>gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]
          Length = 903

 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 55/203 (27%), Positives = 92/203 (45%), Gaps = 17/203 (8%)

Query: 900  LTIDVTEV--VEVGHFWGYRIDENNSEILKKLTAEI----NQLTLVPLPTHPHPDLVCLA 953
            +T++V  V  V  GH +  +        L+ L  ++    +Q  +  LPT     ++C A
Sbjct: 708  ITVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAA 767

Query: 954  PFADFDKQRYFRAQVL--YVSGNSAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEF 1011
            P AD     ++RAQV+  Y   N  E+ +VDYG    V + +L +I   F+ LPFQ  E 
Sbjct: 768  PGAD---GAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEV 824

Query: 1012 KICKMRPSAKSLVCGKHWSDGASQWFASLVSGCTLLVKVFSVVHSVLHVDVYQYSGVQD- 1070
             +  + P    L     +S  A    + +     LL +V S   + L + +  +S V D 
Sbjct: 825  LLDSVMP----LSDDDQFSPEADAAMSEMTGNTALLAQVTSYSPTGLPL-IQLWSVVGDE 879

Query: 1071 AINIRDVLIQQGYAELTEESYES 1093
             + I   L+++G A+  +  Y S
Sbjct: 880  VVLINRSLVERGLAQWVDSYYTS 902


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,307,893
Number of Sequences: 37866
Number of extensions: 2295915
Number of successful extensions: 7210
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 7006
Number of HSP's gapped (non-prelim): 143
length of query: 1382
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1267
effective length of database: 13,892,928
effective search space: 17602339776
effective search space used: 17602339776
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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