Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 16554449
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16554449 zonadhesin isoform 3 [Homo sapiens]
(2812 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 5932 0.0
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 5472 0.0
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens] 878 0.0
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ... 876 0.0
gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr... 686 0.0
gi|134268640 tectorin alpha precursor [Homo sapiens] 638 0.0
gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr... 555 e-157
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens] 366 e-100
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom... 324 9e-88
gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom... 324 9e-88
gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap... 324 9e-88
gi|116284392 mucin 2 precursor [Homo sapiens] 298 7e-80
gi|239757284 PREDICTED: similar to Fc fragment of IgG binding pr... 297 1e-79
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 290 1e-77
gi|134031945 SCO-spondin [Homo sapiens] 286 2e-76
gi|161019170 mucin 5AC [Homo sapiens] 258 8e-68
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 257 1e-67
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] 241 1e-62
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens] 241 1e-62
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens] 241 1e-62
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens] 241 1e-62
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens] 241 1e-62
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens] 241 1e-62
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 231 8e-60
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 213 2e-54
gi|151301154 mucin 6, gastric [Homo sapiens] 207 1e-52
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 197 9e-50
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 192 4e-48
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 192 4e-48
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 192 4e-48
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 5932 bits (15390), Expect = 0.0
Identities = 2812/2812 (100%), Positives = 2812/2812 (100%)
Query: 1 MVPPVWTLLLLVGAALFRKEKPPDQKLVVRSSRDNYVLTQCDFEDDAKPLCDWSQVSADD 60
MVPPVWTLLLLVGAALFRKEKPPDQKLVVRSSRDNYVLTQCDFEDDAKPLCDWSQVSADD
Sbjct: 1 MVPPVWTLLLLVGAALFRKEKPPDQKLVVRSSRDNYVLTQCDFEDDAKPLCDWSQVSADD 60
Query: 61 EDWVRASGPSPTGSTGAPGGYPNGEGSYLHMESNSFHRGGVARLLSPDLWEQGPLCVHFA 120
EDWVRASGPSPTGSTGAPGGYPNGEGSYLHMESNSFHRGGVARLLSPDLWEQGPLCVHFA
Sbjct: 61 EDWVRASGPSPTGSTGAPGGYPNGEGSYLHMESNSFHRGGVARLLSPDLWEQGPLCVHFA 120
Query: 121 HHMFGLSWGAQLRLLLLSGEEGRRPDVLWKHWNTQRPSWMLTTVTVPAGFTLPTRLMFEG 180
HHMFGLSWGAQLRLLLLSGEEGRRPDVLWKHWNTQRPSWMLTTVTVPAGFTLPTRLMFEG
Sbjct: 121 HHMFGLSWGAQLRLLLLSGEEGRRPDVLWKHWNTQRPSWMLTTVTVPAGFTLPTRLMFEG 180
Query: 181 TRGSTAYLDIALDALSIRRGSCNRVCMMQTCSFDIPNDLCDWTWIPTASGAKWTQKKGSS 240
TRGSTAYLDIALDALSIRRGSCNRVCMMQTCSFDIPNDLCDWTWIPTASGAKWTQKKGSS
Sbjct: 181 TRGSTAYLDIALDALSIRRGSCNRVCMMQTCSFDIPNDLCDWTWIPTASGAKWTQKKGSS 240
Query: 241 GKPGVGPDGDFSSPGSGCYMLLDPKNARPGQKAVLLSPVSLSSGCLSFSFHYILRGQSPG 300
GKPGVGPDGDFSSPGSGCYMLLDPKNARPGQKAVLLSPVSLSSGCLSFSFHYILRGQSPG
Sbjct: 241 GKPGVGPDGDFSSPGSGCYMLLDPKNARPGQKAVLLSPVSLSSGCLSFSFHYILRGQSPG 300
Query: 301 AALHIYASVLGSIRKHTLFSGQPGPNWQAVSVNYTAVGRIQFAVVGVFGKTPEPAVAVDA 360
AALHIYASVLGSIRKHTLFSGQPGPNWQAVSVNYTAVGRIQFAVVGVFGKTPEPAVAVDA
Sbjct: 301 AALHIYASVLGSIRKHTLFSGQPGPNWQAVSVNYTAVGRIQFAVVGVFGKTPEPAVAVDA 360
Query: 361 TSIAPCGEGFPQCDFEDNAHPFCDWVQTSGDGGHWALGHKNGPVHGMGPAGGFPNAGGHY 420
TSIAPCGEGFPQCDFEDNAHPFCDWVQTSGDGGHWALGHKNGPVHGMGPAGGFPNAGGHY
Sbjct: 361 TSIAPCGEGFPQCDFEDNAHPFCDWVQTSGDGGHWALGHKNGPVHGMGPAGGFPNAGGHY 420
Query: 421 IYLEADEFSQAGQSVRLVSRPFCAPGDICVEFAYHMYGLGEGTMLELLLGSPAGSPPIPL 480
IYLEADEFSQAGQSVRLVSRPFCAPGDICVEFAYHMYGLGEGTMLELLLGSPAGSPPIPL
Sbjct: 421 IYLEADEFSQAGQSVRLVSRPFCAPGDICVEFAYHMYGLGEGTMLELLLGSPAGSPPIPL 480
Query: 481 WKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLP 540
WKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLP
Sbjct: 481 WKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLP 540
Query: 541 ELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI 600
ELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI
Sbjct: 541 ELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI 600
Query: 601 STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE 660
STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE
Sbjct: 601 STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE 660
Query: 661 PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP 720
PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP
Sbjct: 661 PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP 720
Query: 721 TEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKP 780
TEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKP
Sbjct: 721 TEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKP 780
Query: 781 TIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST 840
TIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST
Sbjct: 781 TIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST 840
Query: 841 EKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLT 900
EKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLT
Sbjct: 841 EKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLT 900
Query: 901 IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTE 960
IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTE
Sbjct: 901 IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTE 960
Query: 961 KPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPH 1020
KPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPH
Sbjct: 961 KPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPH 1020
Query: 1021 APSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGF 1080
APSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGF
Sbjct: 1021 APSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGF 1080
Query: 1081 LFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQL 1140
LFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQL
Sbjct: 1081 LFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQL 1140
Query: 1141 KNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKN 1200
KNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKN
Sbjct: 1141 KNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKN 1200
Query: 1201 EEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ 1260
EEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ
Sbjct: 1201 EEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ 1260
Query: 1261 TEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSW 1320
TEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSW
Sbjct: 1261 TEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSW 1320
Query: 1321 QTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDS 1380
QTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDS
Sbjct: 1321 QTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDS 1380
Query: 1381 CMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCP 1440
CMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCP
Sbjct: 1381 CMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCP 1440
Query: 1441 DTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGC 1500
DTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGC
Sbjct: 1441 DTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGC 1500
Query: 1501 KELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHF 1560
KELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHF
Sbjct: 1501 KELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHF 1560
Query: 1561 MGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVM 1620
MGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVM
Sbjct: 1561 MGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVM 1620
Query: 1621 LNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLC 1680
LNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLC
Sbjct: 1621 LNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLC 1680
Query: 1681 GNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNK 1740
GNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNK
Sbjct: 1681 GNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNK 1740
Query: 1741 NCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP 1800
NCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP
Sbjct: 1741 NCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP 1800
Query: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860
AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS
Sbjct: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860
Query: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920
CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL
Sbjct: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920
Query: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEE 1980
LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEE
Sbjct: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEE 1980
Query: 1981 GGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIK 2040
GGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIK
Sbjct: 1981 GGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIK 2040
Query: 2041 IGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKD 2100
IGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKD
Sbjct: 2041 IGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKD 2100
Query: 2101 KDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLT 2160
KDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLT
Sbjct: 2101 KDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLT 2160
Query: 2161 PFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220
PFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC
Sbjct: 2161 PFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220
Query: 2221 LPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLG 2280
LPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLG
Sbjct: 2221 LPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLG 2280
Query: 2281 KSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYL 2340
KSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYL
Sbjct: 2281 KSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYL 2340
Query: 2341 TFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV 2400
TFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV
Sbjct: 2341 TFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV 2400
Query: 2401 QLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMY 2460
QLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMY
Sbjct: 2401 QLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMY 2460
Query: 2461 EGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQG 2520
EGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQG
Sbjct: 2461 EGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQG 2520
Query: 2521 AELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSA 2580
AELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSA
Sbjct: 2521 AELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSA 2580
Query: 2581 QDPREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLC 2640
QDPREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLC
Sbjct: 2581 QDPREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLC 2640
Query: 2641 LQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLG 2700
LQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLG
Sbjct: 2641 LQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLG 2700
Query: 2701 NHTQGCFPESPCLQNPCQNDGQCREQGATFTCECEVGYGGGLCMEPRDAPPPRKPASNLV 2760
NHTQGCFPESPCLQNPCQNDGQCREQGATFTCECEVGYGGGLCMEPRDAPPPRKPASNLV
Sbjct: 2701 NHTQGCFPESPCLQNPCQNDGQCREQGATFTCECEVGYGGGLCMEPRDAPPPRKPASNLV 2760
Query: 2761 AVLLGLLVPVVVVLLAVTRECIYRTRRKREKTQEGDRLARLVDTDTVLDCAC 2812
AVLLGLLVPVVVVLLAVTRECIYRTRRKREKTQEGDRLARLVDTDTVLDCAC
Sbjct: 2761 AVLLGLLVPVVVVLLAVTRECIYRTRRKREKTQEGDRLARLVDTDTVLDCAC 2812
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 5472 bits (14196), Expect = 0.0
Identities = 2596/2599 (99%), Positives = 2598/2599 (99%)
Query: 1 MVPPVWTLLLLVGAALFRKEKPPDQKLVVRSSRDNYVLTQCDFEDDAKPLCDWSQVSADD 60
MVPPVWTLLLLVGAALFRKEKPPDQKLVVRSSRDNYVLTQCDFEDDAKPLCDWSQVSADD
Sbjct: 1 MVPPVWTLLLLVGAALFRKEKPPDQKLVVRSSRDNYVLTQCDFEDDAKPLCDWSQVSADD 60
Query: 61 EDWVRASGPSPTGSTGAPGGYPNGEGSYLHMESNSFHRGGVARLLSPDLWEQGPLCVHFA 120
EDWVRASGPSPTGSTGAPGGYPNGEGSYLHMESNSFHRGGVARLLSPDLWEQGPLCVHFA
Sbjct: 61 EDWVRASGPSPTGSTGAPGGYPNGEGSYLHMESNSFHRGGVARLLSPDLWEQGPLCVHFA 120
Query: 121 HHMFGLSWGAQLRLLLLSGEEGRRPDVLWKHWNTQRPSWMLTTVTVPAGFTLPTRLMFEG 180
HHMFGLSWGAQLRLLLLSGEEGRRPDVLWKHWNTQRPSWMLTTVTVPAGFTLPTRLMFEG
Sbjct: 121 HHMFGLSWGAQLRLLLLSGEEGRRPDVLWKHWNTQRPSWMLTTVTVPAGFTLPTRLMFEG 180
Query: 181 TRGSTAYLDIALDALSIRRGSCNRVCMMQTCSFDIPNDLCDWTWIPTASGAKWTQKKGSS 240
TRGSTAYLDIALDALSIRRGSCNRVCMMQTCSFDIPNDLCDWTWIPTASGAKWTQKKGSS
Sbjct: 181 TRGSTAYLDIALDALSIRRGSCNRVCMMQTCSFDIPNDLCDWTWIPTASGAKWTQKKGSS 240
Query: 241 GKPGVGPDGDFSSPGSGCYMLLDPKNARPGQKAVLLSPVSLSSGCLSFSFHYILRGQSPG 300
GKPGVGPDGDFSSPGSGCYMLLDPKNARPGQKAVLLSPVSLSSGCLSFSFHYILRGQSPG
Sbjct: 241 GKPGVGPDGDFSSPGSGCYMLLDPKNARPGQKAVLLSPVSLSSGCLSFSFHYILRGQSPG 300
Query: 301 AALHIYASVLGSIRKHTLFSGQPGPNWQAVSVNYTAVGRIQFAVVGVFGKTPEPAVAVDA 360
AALHIYASVLGSIRKHTLFSGQPGPNWQAVSVNYTAVGRIQFAVVGVFGKTPEPAVAVDA
Sbjct: 301 AALHIYASVLGSIRKHTLFSGQPGPNWQAVSVNYTAVGRIQFAVVGVFGKTPEPAVAVDA 360
Query: 361 TSIAPCGEGFPQCDFEDNAHPFCDWVQTSGDGGHWALGHKNGPVHGMGPAGGFPNAGGHY 420
TSIAPCGEGFPQCDFEDNAHPFCDWVQTSGDGGHWALGHKNGPVHGMGPAGGFPNAGGHY
Sbjct: 361 TSIAPCGEGFPQCDFEDNAHPFCDWVQTSGDGGHWALGHKNGPVHGMGPAGGFPNAGGHY 420
Query: 421 IYLEADEFSQAGQSVRLVSRPFCAPGDICVEFAYHMYGLGEGTMLELLLGSPAGSPPIPL 480
IYLEADEFSQAGQSVRLVSRPFCAPGDICVEFAYHMYGLGEGTMLELLLGSPAGSPPIPL
Sbjct: 421 IYLEADEFSQAGQSVRLVSRPFCAPGDICVEFAYHMYGLGEGTMLELLLGSPAGSPPIPL 480
Query: 481 WKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLP 540
WKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLP
Sbjct: 481 WKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLP 540
Query: 541 ELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI 600
ELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI
Sbjct: 541 ELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI 600
Query: 601 STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE 660
STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE
Sbjct: 601 STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE 660
Query: 661 PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP 720
PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP
Sbjct: 661 PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP 720
Query: 721 TEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKP 780
TEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKP
Sbjct: 721 TEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKP 780
Query: 781 TIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST 840
TIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST
Sbjct: 781 TIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST 840
Query: 841 EKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLT 900
EKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLT
Sbjct: 841 EKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLT 900
Query: 901 IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTE 960
IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTE
Sbjct: 901 IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTE 960
Query: 961 KPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPH 1020
KPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPH
Sbjct: 961 KPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPH 1020
Query: 1021 APSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGF 1080
APSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGF
Sbjct: 1021 APSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGF 1080
Query: 1081 LFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQL 1140
LFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQL
Sbjct: 1081 LFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQL 1140
Query: 1141 KNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKN 1200
KNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKN
Sbjct: 1141 KNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKN 1200
Query: 1201 EEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ 1260
EEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ
Sbjct: 1201 EEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ 1260
Query: 1261 TEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSW 1320
TEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSW
Sbjct: 1261 TEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSW 1320
Query: 1321 QTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDS 1380
QTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDS
Sbjct: 1321 QTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDS 1380
Query: 1381 CMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCP 1440
CMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCP
Sbjct: 1381 CMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCP 1440
Query: 1441 DTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGC 1500
DTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGC
Sbjct: 1441 DTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGC 1500
Query: 1501 KELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHF 1560
KELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHF
Sbjct: 1501 KELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHF 1560
Query: 1561 MGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVM 1620
MGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVM
Sbjct: 1561 MGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVM 1620
Query: 1621 LNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLC 1680
LNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLC
Sbjct: 1621 LNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLC 1680
Query: 1681 GNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNK 1740
GNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNK
Sbjct: 1681 GNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNK 1740
Query: 1741 NCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP 1800
NCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP
Sbjct: 1741 NCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP 1800
Query: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860
AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS
Sbjct: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860
Query: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920
CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL
Sbjct: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920
Query: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEE 1980
LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEE
Sbjct: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEE 1980
Query: 1981 GGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIK 2040
GGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIK
Sbjct: 1981 GGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIK 2040
Query: 2041 IGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKD 2100
IGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKD
Sbjct: 2041 IGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKD 2100
Query: 2101 KDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLT 2160
KDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLT
Sbjct: 2101 KDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLT 2160
Query: 2161 PFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220
PFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC
Sbjct: 2161 PFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220
Query: 2221 LPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLG 2280
LPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLG
Sbjct: 2221 LPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLG 2280
Query: 2281 KSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYL 2340
KSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYL
Sbjct: 2281 KSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYL 2340
Query: 2341 TFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV 2400
TFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV
Sbjct: 2341 TFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV 2400
Query: 2401 QLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMY 2460
QLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMY
Sbjct: 2401 QLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMY 2460
Query: 2461 EGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQG 2520
EGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQG
Sbjct: 2461 EGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQG 2520
Query: 2521 AELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSA 2580
AELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSA
Sbjct: 2521 AELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSA 2580
Query: 2581 QDPREQEELRCQVLSGHGV 2599
QDPREQEELRCQVLSG+ +
Sbjct: 2581 QDPREQEELRCQVLSGYAI 2599
Score = 707 bits (1825), Expect = 0.0
Identities = 433/1320 (32%), Positives = 644/1320 (48%), Gaps = 95/1320 (7%)
Query: 1426 CPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPA 1485
CPPN++Y CA CP +C S C C E C CNPGF+ S CI S C C +
Sbjct: 1044 CPPNARYESCA--CPASCKSPRPS--CGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN- 1098
Query: 1486 GSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQ-GAATCTA 1544
Y++ G W+ P C E C C +R+ CQ +C C ++G YGCH G ATC
Sbjct: 1099 NDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLV 1158
Query: 1545 SGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHV 1604
GDPHY+TFDG FMG CTY+L +PC S D +F V+A NE +G VS + V+V
Sbjct: 1159 YGDPHYVTFDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQE-GVSCLSKVYV 1216
Query: 1605 TVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLV 1664
T+ + +++LL+G + ++ G +V LP ++G V + S V L T FGL+VR+DG +
Sbjct: 1217 TLPESTVTLLKGRRTLVGGQQVTLPAIPSKG-VFLGASGRFVELQTEFGLRVRWDGDQQL 1275
Query: 1665 EVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGC--FLV 1722
VTV S+Y G+LCGLCGNY+ NS +D+L+ D AGD +LG +W+ + + C + V
Sbjct: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQV 1335
Query: 1723 GGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTAL 1782
PS + + C L++ GPF C V S F SC+ CG +G L
Sbjct: 1336 VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLL 1395
Query: 1783 CRSLQAYASLCAQAGQA-PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKA 1841
C + + C AG A WR FCPM CPP S YS C+ PCPDTC S + C
Sbjct: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR 1455
Query: 1842 LPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNI 1901
C E+CEC G +LSG C+P QCGC PAGSY VGERWY C LC C +N I
Sbjct: 1456 --CVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPG-CKELCVCESNNRI 1512
Query: 1902 TCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVC 1961
C C+ + C DG+ C A G C G+ HY++FDG+ H CT VL + C
Sbjct: 1513 RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPC 1572
Query: 1962 HPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAIS 2021
+F +SA +E G E + V++ ++D ++L +G +V++N +V LP
Sbjct: 1573 WSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWL 1632
Query: 2022 QIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELM 2081
V+++ SS ++ G+QV++DG+HL+E+ +P++Y G++CG+CGN+N+ D+ +
Sbjct: 1633 AQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNL 1692
Query: 2082 MPSDEVANSDSEFVNSWK-DKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREK 2140
P ++A + +WK + +P C LV + P+ QEN + A K
Sbjct: 1693 RPDRKLAGDSMQLGAAWKLPESSEPGC--FLVGGK--PSSCQENSMAD--------AWNK 1740
Query: 2141 CEAALRAPV--WAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKP 2198
A L P ++QC + C + C G ALC++LQA+ + C G +
Sbjct: 1741 NCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAG-QA 1799
Query: 2199 PLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSE 2258
P WRN +FCP+ CP SSY+ C C +C ++ + K CAE C CQ G++LS
Sbjct: 1800 PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKA-LPCAESCECQKGHILSG 1858
Query: 2259 DKCVPRSQCGCKDAHGGSIPLGKSWVSSG-CTEKCVCT-GGAIQCGDFRCPSGSHCQLTS 2316
CVP QCGC D G P+G+ W + CT C C+ I C C C
Sbjct: 1859 TSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWAL- 1917
Query: 2317 DNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLL-VEG 2375
+ C + C + G+ Y++FDG ++ + T VL+K P P +
Sbjct: 1918 -DGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCH--PAMALPFFKISA 1974
Query: 2376 RNKMDPPRSSIF-LQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRL 2434
+++ + + F L EV +Y +V LQ G +++N++++ +P ++ V++ +
Sbjct: 1975 KHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLP-AISQIPGVSVKSSSI 2033
Query: 2435 YLVTDFEL--VVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNT 2492
Y + + ++ V F G I +P+ Y G V G+CGN++ ++++M+PS + + +
Sbjct: 2034 YSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSE 2093
Query: 2493 FGNSWEVKTED----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACR 2548
F NSW+ K D +LL + IPAE++ + C L +
Sbjct: 2094 FVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPS----------GNCRAADLRRAREKCEA 2143
Query: 2549 VLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYH---- 2604
L P +A C + PF C LC + CQ L G + +
Sbjct: 2144 ALRAPV--WAQCASRIDLTPFLVDCANTLCEFGG---LYQALCQALQAFGATCQSQGLKP 2198
Query: 2605 ---------------ISELYDTLPSILCQP------GRPRGLRGP---LRGRLRQHPRLC 2640
S + LPS C P GR G + P G + Q P
Sbjct: 2199 PLWRNSSFCPLECPAYSSYTNCLPS--CSPSCWDLDGRCEGAKVPSACAEGCICQ-PGYV 2255
Query: 2641 LQWHPEPPLADCGCT-SNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTL 2699
L P + CGC ++G LG S+++ C+++C C I C F C +G C L
Sbjct: 2256 LSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAI-QCGDFRCPSGSHCQL 2314
Score = 701 bits (1808), Expect = 0.0
Identities = 407/1213 (33%), Positives = 606/1213 (49%), Gaps = 62/1213 (5%)
Query: 1044 CPPNARYESCA--CPASCKSPRPS--CGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN- 1098
CPPN++Y CA CP +C S C C E C CNPGF+ S CI S C C +
Sbjct: 1426 CPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPA 1485
Query: 1099 NDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLV 1158
Y++ G W+ P C E C C +R+ CQ +C C ++G YGCH G ATC
Sbjct: 1486 GSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQ-GAATCTA 1544
Query: 1159 YGDPHYVTFDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQE-GVSCLSKVYV 1216
GDPHY+TFDG FMG CTY+L +PC S D +F V+A NE +G VS + V+V
Sbjct: 1545 SGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHV 1604
Query: 1217 TLPESTVTLLKGRRTLVGGQQVTLPAIPSKG-VFLGASGRFVELQTEFGLRVRWDGDQQL 1275
T+ + +++LL+G + ++ G +V LP ++G V + S V L T FGL+VR+DG +
Sbjct: 1605 TVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLV 1664
Query: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQV 1335
VTV S+Y G+LCGLCGNY+ NS +D+L+ D AGD +LG +W+ + + C + V
Sbjct: 1665 EVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGC--FLV 1722
Query: 1336 VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLL 1395
PS + + C L++ GPF C V S F SC+ CG +G L
Sbjct: 1723 GGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTAL 1782
Query: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR 1455
C + + C AG A WR FCPM CPP S YS C+ PCPDTC S + C
Sbjct: 1783 CRSLQAYASLCAQAGQA-PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKA 1841
Query: 1456 --CVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPG-CKELCVCESNNRI 1512
C E+CEC G +LSG C+P QCGC PAGSY VGERWY C LC C +N I
Sbjct: 1842 LPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNI 1901
Query: 1513 RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPC 1572
C C+ + C DG+ C A G C G+ HY++FDG+ H CT VL + C
Sbjct: 1902 TCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVC 1961
Query: 1573 WSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWL 1632
+F +SA +E G E + V++ ++D ++L +G +V++N +V LP
Sbjct: 1962 HPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAIS 2021
Query: 1633 AQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNL 1692
V+++ SS ++ G+QV++DG+HL+E+ +P++Y G++CG+CGN+N+ D+ +
Sbjct: 2022 QIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELM 2081
Query: 1693 RPDRKLAGDSMQLGAAWKLPESSEPGC--FLVGGK--PSSCQENSMAD--------AWNK 1740
P ++A + +WK + +P C LV + P+ QEN + A K
Sbjct: 2082 MPSDEVANSDSEFVNSWK-DKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREK 2140
Query: 1741 NCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAG-QA 1799
A L P ++QC + C + C G ALC++LQA+ + C G +
Sbjct: 2141 CEAALRAPV--WAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKP 2198
Query: 1800 PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKA-LPCAESCECQKGHILSG 1858
P WRN +FCP+ CP SSY+ C C +C ++ + K CAE C CQ G++LS
Sbjct: 2199 PLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSE 2258
Query: 1859 TSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWAL- 1917
CVP QCGC D G P+G+ W + CT C C+ I C C C
Sbjct: 2259 DKCVPRSQCGCKDAHGGSIPLGKSWVSSG-CTEKCVCT-GGAIQCGDFRCPSGSHCQLTS 2316
Query: 1918 -DGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCH--PAMALPFFKISA 1974
+ C + C + G+ Y++FDG ++ + T VL+K P P +
Sbjct: 2317 DNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLL-VEG 2375
Query: 1975 KHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLP-AISQIPGVSVKSSSI 2033
+++ + + F L EV +Y +V LQ G +++N++++ +P ++ V++ +
Sbjct: 2376 RNKMDPPRSSIF-LQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRL 2434
Query: 2034 YSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSE 2093
Y + + ++ V F G I +P+ Y G V G+CGN++ ++++M+PS + + +
Sbjct: 2435 YLVTDFEL--VVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNT 2492
Query: 2094 FVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPS----------GNCRAADLRRAREKCEA 2143
F NSW+ K D +LL + IPAE++ + C L +
Sbjct: 2493 FGNSWEVKTED----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACR 2548
Query: 2144 ALRAPV--WAQCASRIDLTPFLVDCANTLCEFGG---LYQALCQALQAFGATCQSQGLKP 2198
L P +A C + PF C LC + CQ L + CQ G
Sbjct: 2549 VLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAAL 2608
Query: 2199 PLWRNSSFCPLEC 2211
WR+ + C C
Sbjct: 2609 AGWRDRTLCESPC 2621
Score = 405 bits (1040), Expect = e-112
Identities = 267/917 (29%), Positives = 402/917 (43%), Gaps = 75/917 (8%)
Query: 1811 RCPPGSSYSPCSSPCPDTCSSINNPRDCPKALP-CAESCECQKGHILSGTSCVPLGQCGC 1869
RCPP + Y C+ CP +C S PR P P C E C C G + S C+ C C
Sbjct: 1043 RCPPNARYESCA--CPASCKS---PR--PSCGPLCREGCVCNPGFLFSDNHCIQASSCNC 1095
Query: 1870 TDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRA-SGV 1928
Y P G W++ N CT C C + + C S C + +C +G C +G
Sbjct: 1096 FYNNDYYEP-GAEWFSPN-CTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGT 1153
Query: 1929 GVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRL 1988
C + G+ HYV+FDG + CT +L + C + PFF+++AK+E E+G L
Sbjct: 1154 ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTD-PFFRVTAKNE-EQGQEGVSCL 1211
Query: 1989 HEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFD 2048
+VY+ + ++ VTL KG R L+ +QVTLPAI GV + +S + + + G++V++D
Sbjct: 1212 SKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPS-KGVFLGASGRFVELQTEFGLRVRWD 1270
Query: 2049 GNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWK-DKDIDPSC 2107
G+ L + + +TY GK+CG+CGN++ +++ + A E NSW+ D+D D C
Sbjct: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330
Query: 2108 QSL-LVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDC 2166
Q +V+ + Q + SG L E C + F C
Sbjct: 1331 QKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFET---------CLLHVKAASFFDSC 1381
Query: 2167 ANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSP 2226
+C F GL LC + TCQ G WR FCP+ CP S Y+ C C
Sbjct: 1382 MLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPD 1441
Query: 2227 SCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSS 2286
+C G C E C C PG+VLS +C+PRSQCGC G +G+ W
Sbjct: 1442 TC---HSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKP 1498
Query: 2287 GCTEKCVC-TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGF 2345
GC E CVC + I+C +RC + C + C + + C+ GDP YLTFDG
Sbjct: 1499 GCKELCVCESNNRIRCQPWRCRAQEFCG--QQDGIYGCHAQGAATCTASGDPHYLTFDGA 1556
Query: 2346 SYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAG 2405
+ G TYVL + + ++ +++ V TV+ + L G
Sbjct: 1557 LHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRG 1616
Query: 2406 LELVVNNQKMAVP-YRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLV 2464
++++N ++A+P + + + L + L T+F L V + G +++PS Y G +
Sbjct: 1617 CKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQL 1676
Query: 2465 SGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELG 2524
GLCGNY+ N +D + P L + G +W++ E G L
Sbjct: 1677 CGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLP--------------ESSEPGCFL- 1721
Query: 2525 LRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLC------ 2578
G + S C +A + C +L +PQGPF+ CHQ V P+ CV C
Sbjct: 1722 --VGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDT 1779
Query: 2579 ----------------SAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRP 2622
+ Q P + C + G S S DT SI P
Sbjct: 1780 TALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP 1839
Query: 2623 RGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSN-GIYYQLGSSFLTED-CSQRCTCAS 2680
+ L P L PL CGCT G Y+ +G + TE+ C++ CTC+
Sbjct: 1840 KAL--PCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSV 1897
Query: 2681 SRILLCEPFSCRAGEVC 2697
+ C +C+ ++C
Sbjct: 1898 HNNITCFQSTCKPNQIC 1914
Score = 223 bits (567), Expect = 3e-57
Identities = 112/138 (81%), Positives = 114/138 (82%), Gaps = 6/138 (4%)
Query: 2675 RCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQCREQGATFTCEC 2734
RC S +LC+ AG L ESPCLQNPCQNDGQCREQGATFTCEC
Sbjct: 2590 RCQVLSGYAILCQ----EAG--AALAGWRDRTLCESPCLQNPCQNDGQCREQGATFTCEC 2643
Query: 2735 EVGYGGGLCMEPRDAPPPRKPASNLVAVLLGLLVPVVVVLLAVTRECIYRTRRKREKTQE 2794
EVGYGGGLCMEPRDAPPPRKPASNLVAVLLGLLVPVVVVLLAVTRECIYRTRRKREKTQE
Sbjct: 2644 EVGYGGGLCMEPRDAPPPRKPASNLVAVLLGLLVPVVVVLLAVTRECIYRTRRKREKTQE 2703
Query: 2795 GDRLARLVDTDTVLDCAC 2812
GDRLARLVDTDTVLDCAC
Sbjct: 2704 GDRLARLVDTDTVLDCAC 2721
Score = 183 bits (465), Expect = 2e-45
Identities = 141/522 (27%), Positives = 217/522 (41%), Gaps = 57/522 (10%)
Query: 2211 CPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCK 2270
CP + Y +C +C SC C C EGC+C PG++ S++ C+ S C C
Sbjct: 1044 CPPNARYESC--ACPASCKSPRPSCG-----PLCREGCVCNPGFLFSDNHCIQASSCNCF 1096
Query: 2271 DAHGGSIPLGKSWVSSGCTEKCVC-TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSE 2329
+ P G W S CTE C C G ++C +C + + CQL + + + +
Sbjct: 1097 YNNDYYEP-GAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTAT 1155
Query: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLL-VEGRNKMDPPRSSIFL 2388
C VYGDP Y+TFDG + G+ TY+L + +P V +N+ L
Sbjct: 1156 -CLVYGDPHYVTFDGRHFGFMGKCTYILAQPCG---NSTDPFFRVTAKNEEQGQEGVSCL 1211
Query: 2389 QEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGG 2448
+V T+ V L G +V Q++ +P P++ + + G+ + L T+F L V + G
Sbjct: 1212 SKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDG 1271
Query: 2449 RKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRF 2508
+ +++ S Y G + GLCGNYD N ND + G+ + GNSW+ ++
Sbjct: 1272 DQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDE----- 1326
Query: 2509 PRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQA-CRVLADPQGPFAACHQTVAPE 2567
++E Q ++ + C +S S C L D GPF C V
Sbjct: 1327 ------DQECQKYQV-----VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAA 1375
Query: 2568 PFQEHCVLDLCSAQDPREQEELRCQVLS---------GHGVSS--RYHISELYDTLPS-- 2614
F + C+LD+C Q + L C +S GH V H + S
Sbjct: 1376 SFFDSCMLDMCGFQG---LQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKY 1432
Query: 2615 ILCQPGRPRGLRGPLRGRLRQ---------HPRLCLQWHPEPPLADCGCTSN-GIYYQLG 2664
LC P G +P L P + CGC G Y+++G
Sbjct: 1433 SLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVG 1492
Query: 2665 SSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGC 2706
+ C + C C S+ + C+P+ CRA E C + GC
Sbjct: 1493 ERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGC 1534
Score = 181 bits (460), Expect = 7e-45
Identities = 127/454 (27%), Positives = 195/454 (42%), Gaps = 48/454 (10%)
Query: 1044 CPPNARYESC--ACPASCKSPRPSCG-----PLCREGCVCNPGFLFSDNHCIQASSCNCF 1096
CP + Y +C +C SC C C EGC+C PG++ S++ C+ S C C
Sbjct: 2211 CPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCK 2270
Query: 1097 YNNDYYEP-GAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTAT 1155
+ P G W S CTE C C G ++C +C + + CQL + + + +
Sbjct: 2271 DAHGGSIPLGKSWVSSGCTEKCVC-TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSE 2329
Query: 1156 -CLVYGDPHYVTFDGRHFGFMGKCTYILAQPCG---NSTDPFFRVTAKNEEQGQEGVSCL 1211
C VYGDP Y+TFDG + G+ TY+L + +P V +N+ L
Sbjct: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLL-VEGRNKMDPPRSSIFL 2388
Query: 1212 SKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDG 1271
+V T+ V L G +V Q++ +P P++ + + G+ + L T+F L V + G
Sbjct: 2389 QEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGG 2448
Query: 1272 DQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDE----- 1326
+ +++ S Y G + GLCGNYD N ND + G+ + GNSW+ ++
Sbjct: 2449 RKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRF 2508
Query: 1327 ------DQECQKYQV-----VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAA 1375
++E Q ++ + C +S S C L D GPF C V
Sbjct: 2509 PRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQA-CRVLADPQGPFAACHQTVAPE 2567
Query: 1376 SFFDSCMLDMCGFQG---LQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKY 1432
F + C+LD+C Q + L C +S CQ+AG A+ WR+ C C N
Sbjct: 2568 PFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQN--- 2624
Query: 1433 SLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGF 1466
PC + G CEC G+
Sbjct: 2625 -----PCQN------DGQCREQGATFTCECEVGY 2647
Score = 45.4 bits (106), Expect = 8e-04
Identities = 18/59 (30%), Positives = 28/59 (47%)
Query: 2650 ADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFP 2708
+ C C N YY+ G+ + + +C++ C C + C+ C VC L N GC P
Sbjct: 1091 SSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHP 1149
>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
Length = 5405
Score = 878 bits (2269), Expect = 0.0
Identities = 565/1787 (31%), Positives = 809/1787 (45%), Gaps = 152/1787 (8%)
Query: 1043 RCPPNARYESC--ACPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
+CP ++ YE C +CP SC S C CREGCVC+ GF+ S + C+ C C ++
Sbjct: 2336 QCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 2395
Query: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCL 1157
+ YY G ++ P C CRC G V C+ S CG H C+ G GC G+ TC
Sbjct: 2396 DRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGC-VAVGSTTCQ 2454
Query: 1158 VYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPF-FRVTAKNEEQGQEGVSCLSKVYV 1216
GDPHY TFDGR F FMG C Y+LAQ CG F V +N G VS + V
Sbjct: 2455 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 2514
Query: 1217 TLPESTVTLLKGR-RTLVGGQQVTLPAIPSKG-VFLGASGRFVELQTEFGLRVRWDGDQQ 1274
+ T+ L + + + V G + LP + + G + G V ++T+FGLRV +D
Sbjct: 2515 QVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYY 2574
Query: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC---- 1330
+ VTV Y +CGLCGNY+G+ +D K +GS AG+ E GNSW+ + D C
Sbjct: 2575 VRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWE-EVVPDSPCLPPP 2633
Query: 1331 ----QKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMC 1386
+ S C L+ FCG L GP +C V C+ D+C
Sbjct: 2634 TCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLC 2693
Query: 1387 GFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSG 1446
G +LC+++ + CQ AG V+PWR FCPM CP NS Y LCA C C +
Sbjct: 2694 LGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSAL 2753
Query: 1447 FSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVC 1506
+ + C D C E C+C+ GF+ +G C+P QCGC H G+Y++ + C++ C C
Sbjct: 2754 SAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYH-NGAYYEPEQTVLIDNCRQQCTC 2812
Query: 1507 ESNNRIRCQPW--------------------------RCRAQEFCGQQDGIYGCHAQGAA 1540
+ CQ CR QE C +Q G C A
Sbjct: 2813 HVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEA 2872
Query: 1541 TCTASGDPHYLTFDGALHHFMGTCTYVLTR---PCWSRSQDSYFVVSATNENRGGILEVS 1597
TC GDPHY +FDG F GTC YVL P S + F V+ N+NRG VS
Sbjct: 2873 TCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGN-PAVS 2931
Query: 1598 YIKAVHVTVFDLSISLLRG--CKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQ 1655
Y++ V V +IS+ + KV +NG ALPV +A GR+++ ++ LL +FGLQ
Sbjct: 2932 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQ 2991
Query: 1656 VRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESS 1715
V YD + V+VT+PSSY G +CGLCGN + N +D + P+ LA G +W+ P
Sbjct: 2992 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP-GW 3050
Query: 1716 EPGCF-LVGGKPSSCQENSMADAWNKNCAILINP--QGPFSQCHQVVPPQSSFASCVHGQ 1772
+P C+ G +C E+ + + P GPF+ CH VPP+S F CV
Sbjct: 3051 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 3110
Query: 1773 CGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSS 1831
C GD LC++L +Y + C AG WR + C + CP S Y C PCP +C S
Sbjct: 3111 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 3170
Query: 1832 ---INNPRDCPKALPCAESCECQKGHILSGTSCVPLGQ-CGCTDPAGSYHPVGERWYTEN 1887
+ P C PC E C+C G +LS CVPL CGC G+YH G ++ +
Sbjct: 3171 PAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADG 3227
Query: 1888 TCTRLCTCSV-HNNITCFQSTCKPNQICWAL-DGLLRCRASGVGVCQLPGESHYVSFDGS 1945
TC++ C C ++ C ++C ++C L G C+ CQ G+ HYV+ DG
Sbjct: 3228 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGH 3287
Query: 1946 NHSIPDACTLVLVKVCH-PAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQK 2004
C +L CH P + F ++ +E G V + IY+ +TL
Sbjct: 3288 RFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE-HRGSQAVSYTRSVTLQIYNHSLTLSA 3346
Query: 2005 --GHRVLINSKQVTLP-AISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTY 2061
++ ++ VTLP + + + + + +V G+ + FDG+ + + +P Y
Sbjct: 3347 RWPRKLQVDGVFVTLPFQLDSLLHAHLSGADV--VVTTTSGLSLAFDGDSFVRLRVPAAY 3404
Query: 2062 YGKVCGMCGNFNDEEEDELMMPSDEVAN---SDSEFVNSWKDKDIDPSCQSLLVDEQQIP 2118
G +CG+CGN+N + D+L + A ++ K C
Sbjct: 3405 AGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPC----------T 3454
Query: 2119 AEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQ 2178
EQQE+ G + +A P+ A C + + C C+ G
Sbjct: 3455 PEQQESFGGPDACGVI--------SATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHPG 3505
Query: 2179 ALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGA 2238
LC A+ + A CQ+ G + WR FCP +CPA+S Y C SC SC L EG
Sbjct: 3506 GLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAP-EGC 3564
Query: 2239 KVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKS-WVSSGCTEKCVC-TG 2296
+ SAC EGC+C G+VLS D CVP QCGC PLG++ + GC C C G
Sbjct: 3565 E--SACREGCVCDAGFVLSGDTCVPVGQCGCLH-DDRYYPLGQTFYPGPGCDSLCRCREG 3621
Query: 2297 GAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYV 2356
G + C C G H + CV+ S C GDP Y TFDG + G YV
Sbjct: 3622 GEVSCEPSSC--GPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYV 3679
Query: 2357 LIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITT-VYGYKVQL-QAGLELVVNNQK 2414
L +T P G+ V N + + + VIT V + ++L Q ++ VN
Sbjct: 3680 LAQTCGTRP-GLHRFAVLQEN-VAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVD 3737
Query: 2415 MAVP-YRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDK 2473
M +P N +R + G + + TDF L V++ +++P Y L+ GLCGNY+
Sbjct: 3738 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG 3797
Query: 2474 NRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSE 2533
+ K+D P+G+ N N FGNSWE D+ P P G + +
Sbjct: 3798 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAG---------CIPSDK 3848
Query: 2534 CSPE-QLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQ-------DPRE 2585
C PE + + C +L+ P GP ++CH+ V P+ + C+ DLC
Sbjct: 3849 CPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIH 3908
Query: 2586 QEELRCQVLSGH------------GVSSRYHISELYDTL--------PSILCQPGRPRGL 2625
CQ GH H DT + C G G
Sbjct: 3909 AYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGC 3968
Query: 2626 RGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILL 2685
+ + + C+ P+ CGC NG+YY+ + L ++C Q+CTC ++++
Sbjct: 3969 Q--CDSGFLYNGQACV------PIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVV 4020
Query: 2686 CEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQCREQGATFTC 2732
C+ SC+ G+VC C + PC C+ C+EQG C
Sbjct: 4021 CQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVC 4067
Score = 874 bits (2257), Expect = 0.0
Identities = 562/1756 (32%), Positives = 788/1756 (44%), Gaps = 152/1756 (8%)
Query: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
CP N+ YE C CPASC SP P P C EGC C+ GF+ S + C+ ++ C C
Sbjct: 1950 CPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 2009
Query: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
+ N Y+E G+E W C++ CRC PG + C + CG VC L +GQ+GC P +
Sbjct: 2010 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 2068
Query: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
TA C +GDPHYVT DG F F G C Y+L+ PC F VT NE +G + VS
Sbjct: 2069 TAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 2128
Query: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
V + + ++TL R+ V G VTLP + SG V + T GL +
Sbjct: 2129 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLA 2188
Query: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
+DGD + + V + Y+G LCGLCGNY+ + +D + G PAG WQ Q
Sbjct: 2189 FDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 2238
Query: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
C + PS C Q S GP CG + T GP C V A +F C+LD C
Sbjct: 2239 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 2298
Query: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
QG LC ++T CQ AG ++ WR P FCP CP +S Y LC CP +C S
Sbjct: 2299 VQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLS 2358
Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
+ C C E C C+ GFVLSG C+P QCGCLH Y+ +G+ +Y PGC LC C
Sbjct: 2359 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-DRYYPLGQTFYPGPGCDSLCRC 2417
Query: 1507 ESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTY 1566
+ C+P C E C G GC A G+ TC ASGDPHY TFDG FMGTC Y
Sbjct: 2418 REGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVY 2477
Query: 1567 VLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
VL + C +R F V N G G + V+ + V V F L + R KV +NG
Sbjct: 2478 VLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE-QRQWKVTVNGVD 2536
Query: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
+ LPV LA G++ + V++ T+FGL+V YD + V VTVP +Y +CGLCGNYN
Sbjct: 2537 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG 2596
Query: 1686 NSLDDNLRPDRKLAGDSMQLGAAWK--LPES----------SEPGCFLVGGKPSSCQENS 1733
+ DD +P+ AG++ + G +W+ +P+S GC P ++
Sbjct: 2597 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKY 2656
Query: 1734 MADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLC 1793
+ + C +L +P GP S CH++V PQ C+ C G+ + LC ++ AY S C
Sbjct: 2657 QKEEF---CGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 2713
Query: 1794 -AQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQK 1852
A GQ WRN TFCPM CP S Y C+ C CS+++ P CP CAE C+C
Sbjct: 2714 QAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDG--CAEGCQCDS 2771
Query: 1853 GHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQ 1912
G + +G +CVP+ QCGC Y P E+ + C + CTC V + C + +CKP Q
Sbjct: 2772 GFLYNGQACVPIQQCGCYHNGAYYEP--EQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQ 2829
Query: 1913 ICWALDGLLRC------------------RASGVGV--------CQLPGESHYVSFDGSN 1946
+C G+L C G GV C L G+ HY SFDG
Sbjct: 2830 VCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRK 2889
Query: 1947 HSIPDACTLVLVKVCHPAMA---LPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQ 2003
C VL P ++ L F ++ K++ G + V + +++
Sbjct: 2890 FDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ-NRGNPAVSYVRVVTVAALGTNISIH 2948
Query: 2004 KGH--RVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTY 2061
K +V +N LP +SV + +++ G+QV +D N +++ +P++Y
Sbjct: 2949 KDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSY 3008
Query: 2062 YGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDP----SCQSLLVDEQQI 2117
+G VCG+CGN + ++ + P+ +A S + SW+ DP C+ +
Sbjct: 3009 HGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPED 3068
Query: 2118 PAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLY 2177
EQ E P G C A + C + + F C +C GG
Sbjct: 3069 RLEQYEGP-GFCGPL----------APGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDR 3117
Query: 2178 QALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEG 2237
LC+AL ++ A CQ+ G+ WR C + CP S Y C P C SC
Sbjct: 3118 DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTP 3177
Query: 2238 AKVPSACAEGCICQPGYVLSEDKCVP-RSQCGCKDAHGGSIPLGKS-WVSSGCTEKCVC- 2294
A C EGC C G+VLS D+CVP + CGC A+G G W C++ C C
Sbjct: 3178 AVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADGTCSQWCRCG 3236
Query: 2295 -TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRM 2353
GG++ C C G C L + C + +C +GDP Y+T DG + QG
Sbjct: 3237 PGGGSLVCTPASCGLGEVCGLLPSGQH-GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTC 3295
Query: 2354 TYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQA--GLELVVN 2411
Y+L P G E V N+ ++ + + V +Y + + L A +L V+
Sbjct: 3296 EYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 3355
Query: 2412 NQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNY 2471
+ +P++ + L L G + + T L ++F G + +P+ Y G + GLCGNY
Sbjct: 3356 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 3415
Query: 2472 DKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQV 2531
+++ +D+ G W+V +G G +
Sbjct: 3416 NQDPADDLKAVGGKPA--------GWQV--------------GGAQGCGECVSKPC---P 3450
Query: 2532 SECSPEQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQD-------- 2582
S C+PEQ S AC V++ GP A CH V P + + C+LD C Q
Sbjct: 3451 SPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPA 3510
Query: 2583 -----------PREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRPRGLRGPLRG 2631
+ E R + H D+ P P G R
Sbjct: 3511 VATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACRE 3570
Query: 2632 RLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLT-EDCSQRCTCASSRILLCEPFS 2690
L P+ CGC + YY LG +F C C C + CEP S
Sbjct: 3571 GCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSS 3630
Query: 2691 CRAGEVCTLGNHTQGC 2706
C E C + GC
Sbjct: 3631 CGPHETCRPSGGSLGC 3646
Score = 866 bits (2238), Expect = 0.0
Identities = 564/1756 (32%), Positives = 814/1756 (46%), Gaps = 154/1756 (8%)
Query: 1043 RCPPNARYESC--ACPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
+CP ++ YE C +CP SC S C CREGCVC+ GF+ S + C+ C C ++
Sbjct: 3537 QCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 3596
Query: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCL 1157
+ YY G ++ P C CRC G V C+ S CG H C+ G GC G+ TC
Sbjct: 3597 DRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGC-VAVGSTTCQ 3655
Query: 1158 VYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPF-FRVTAKNEEQGQEGVSCLSKVYV 1216
GDPHY TFDG F FMG C Y+LAQ CG F V +N G VS + V
Sbjct: 3656 ASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 3715
Query: 1217 TLPESTVTLLKGR-RTLVGGQQVTLPAIPSKG-VFLGASGRFVELQTEFGLRVRWDGDQQ 1274
+ T+ L + + + V G + LP + + G + G V ++T+FGLRV +D
Sbjct: 3716 QVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYY 3775
Query: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC---- 1330
+ VTV Y +CGLCGNY+G+ +D K +GS AG+ E GNSW+ + D C
Sbjct: 3776 VRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWE-EVVPDSPCLPPP 3834
Query: 1331 ----QKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMC 1386
+ S C L+ FCG L GP +C V C+ D+C
Sbjct: 3835 TCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLC 3894
Query: 1387 GFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSG 1446
G +LC+++ + CQ AG V+PWR FCPM CP NS Y LCA C C +
Sbjct: 3895 LGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSAL 3954
Query: 1447 FSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVC 1506
+ + C D C E C+C+ GF+ +G C+P QCGC H G Y++ + C++ C C
Sbjct: 3955 SAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTC 4013
Query: 1507 ESNNRIRCQPW--------------------------RCRAQEFCGQQDGIYGCHAQGAA 1540
+ CQ CR QE C +Q G C A
Sbjct: 4014 HVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEA 4073
Query: 1541 TCTASGDPHYLTFDGALHHFMGTCTYVLTR---PCWSRSQDSYFVVSATNENRGGILEVS 1597
TC GDPHY +FDG F GTC YVL P S + F V+ N+NRG VS
Sbjct: 4074 TCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGN-PAVS 4132
Query: 1598 YIKAVHVTVFDLSISLLRG--CKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQ 1655
Y++ V V +IS+ + KV +NG ALPV +A GR+++ ++ LL +FGLQ
Sbjct: 4133 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQ 4192
Query: 1656 VRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESS 1715
V YD + V+VT+PSSY G +CGLCGN + N +D + P+ LA G +W+ P
Sbjct: 4193 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP-GW 4251
Query: 1716 EPGCF-LVGGKPSSCQENSMADAWNKN-CAILIN-PQGPFSQCHQVVPPQSSFASCVHGQ 1772
+P C+ G +C E+ + C L + GPF+ CH VPP+S F CV
Sbjct: 4252 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV 4311
Query: 1773 CGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSS 1831
C GD LC++L +Y + C AG WR + C + CP S Y C PCP +C S
Sbjct: 4312 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 4371
Query: 1832 ---INNPRDCPKALPCAESCECQKGHILSGTSCVPLGQ-CGCTDPAGSYHPVGERWYTEN 1887
+ P C PC E C+C G +LS CVPL CGC G+YH G ++ +
Sbjct: 4372 PAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADG 4428
Query: 1888 TCTRLCTCSV-HNNITCFQSTCKPNQICWAL-DGLLRCRASGVGVCQLPGESHYVSFDGS 1945
TC++ C C ++ C ++C ++C L G C+ CQ G+ HYV+ DG
Sbjct: 4429 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGH 4488
Query: 1946 NHSIPDACTLVLVKVCH-PAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQK 2004
C +L CH P + F ++ +E G V + IY+ +TL
Sbjct: 4489 RFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE-HRGSQAVSYTRSVTLQIYNHSLTLSA 4547
Query: 2005 --GHRVLINSKQVTLP-AISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTY 2061
++ ++ V LP + + + + + +V G+ + FDG+ + + +P Y
Sbjct: 4548 RWPRKLQVDGVFVALPFQLDSLLHAHLSGADV--VVTTTSGLSLAFDGDSFVRLRVPAAY 4605
Query: 2062 YGKVCGMCGNFNDEEEDELMMPSDEVAN---SDSEFVNSWKDKDIDPSCQSLLVDEQQIP 2118
+CG+CGN+N + D+L + A ++ K C
Sbjct: 4606 AASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPC----------T 4655
Query: 2119 AEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQ 2178
EQQE+ G + +A P+ A C + + C C+ G
Sbjct: 4656 PEQQESFGGPDACGVI--------SATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHPG 4706
Query: 2179 ALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGA 2238
LC A+ + A CQ+ G + WR FCPL+CPA+S Y C SC SC L EG
Sbjct: 4707 GLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP-EGC 4765
Query: 2239 KVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGK-SWVSSGCTEKCVC-TG 2296
+ SAC EGC+C G+VLS D CVP QCGC G PLG+ + C +C C G
Sbjct: 4766 E--SACREGCVCDAGFVLSGDTCVPVGQCGCLH-DGRYYPLGEVFYPGPECERRCECGPG 4822
Query: 2297 GAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYV 2356
G + C + G H + ++ C + +C G Y+T DG Y L G +YV
Sbjct: 4823 GHVTCQE-GAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYV 4881
Query: 2357 LIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMA 2416
L + P + +V +N LQ ++ TV G V L G ++ V+ + +A
Sbjct: 4882 LAQVCHPKPGDEDFSIVLEKNAAGD------LQRLLVTVAGQVVSLAQGQQVTVDGEAVA 4935
Query: 2417 VPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRK 2476
+P +RVT G+ + L T L + F G + ++S+PS + G + GLCGN++ N
Sbjct: 4936 LPVAVG-RVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWS 4994
Query: 2477 NDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSP 2536
+D +LP+G+ ++ TFG +W P +G G G + G V C
Sbjct: 4995 DDFVLPNGSAASSVETFGAAWRA-------------PGSSKGCGEGCGPQ-GCPV--CLA 5038
Query: 2537 EQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLS 2595
E+ A S +AC L +PQGPFA C ++P + CV DLC+ + + C+ L+
Sbjct: 5039 EETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA---QKGDKAFLCRSLA 5095
Query: 2596 GH-------GVSSR----------YHISELYDTLPSILCQPGRPRGLRGPLRGRLRQ--- 2635
+ GV+ + + + + ++ + CQ G L G L G +
Sbjct: 5096 AYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQ-GSCAALSG-LTGCTTRCFE 5153
Query: 2636 ----HPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSC 2691
R L P+ DCGCT NG Y + SS LT DCS+RC+C+SS L C+ C
Sbjct: 5154 GCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGC 5213
Query: 2692 RAGEVCTLGNHTQGCF 2707
G VC + + C+
Sbjct: 5214 PPGRVCEVKAEARNCW 5229
Score = 866 bits (2237), Expect = 0.0
Identities = 563/1757 (32%), Positives = 792/1757 (45%), Gaps = 153/1757 (8%)
Query: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
CP N+ YE C CPASC SP P P C EGC C+ GF+ S + C+ ++ C C
Sbjct: 3151 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 3210
Query: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
+ N Y+E G+E W C++ CRC PG + C + CG VC L +GQ+GC P +
Sbjct: 3211 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 3269
Query: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
TA C +GDPHYVT DG F F G C Y+L+ PC F VT NE +G + VS
Sbjct: 3270 TAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 3329
Query: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
V + + ++TL R+ V G VTLP + SG V + T GL +
Sbjct: 3330 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLA 3389
Query: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
+DGD + + V + Y+G LCGLCGNY+ + +D + G PAG WQ Q
Sbjct: 3390 FDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 3439
Query: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
C + PS C Q S GP CG + T GP C V A +F C+LD C
Sbjct: 3440 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 3499
Query: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
QG LC ++T CQ AG ++ WR P FCP CP +S Y LC CP +C S
Sbjct: 3500 VQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLS 3559
Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
+ C C E C C+ GFVLSG C+P QCGCLH Y+ +G+ +Y PGC LC C
Sbjct: 3560 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-DRYYPLGQTFYPGPGCDSLCRC 3618
Query: 1507 ESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTY 1566
+ C+P C E C G GC A G+ TC ASGDPHY TFDG FMGTC Y
Sbjct: 3619 REGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVY 3678
Query: 1567 VLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
VL + C +R F V N G G + V+ + V V F L + R KV +NG
Sbjct: 3679 VLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE-QRQWKVTVNGVD 3737
Query: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
+ LPV LA G++ + V++ T+FGL+V YD + V VTVP +Y +CGLCGNYN
Sbjct: 3738 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG 3797
Query: 1686 NSLDDNLRPDRKLAGDSMQLGAAWK--LPES----------SEPGCFLVGGKPSSCQENS 1733
+ DD +P+ AG++ + G +W+ +P+S GC P ++
Sbjct: 3798 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKY 3857
Query: 1734 MADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLC 1793
+ + C +L +P GP S CH++V PQ C+ C G+ + LC ++ AY S C
Sbjct: 3858 QKEEF---CGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 3914
Query: 1794 -AQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQK 1852
A G WRN TFCPM CP S Y C+ C CS+++ P CP CAE C+C
Sbjct: 3915 QAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDG--CAEGCQCDS 3972
Query: 1853 GHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQ 1912
G + +G +CVP+ QCGC Y P E+ + C + CTC V + C + +CKP Q
Sbjct: 3973 GFLYNGQACVPIQQCGCYHNGVYYEP--EQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQ 4030
Query: 1913 ICWALDGLLRC------------------RASGVGV--------CQLPGESHYVSFDGSN 1946
+C G+L C G GV C L G+ HY SFDG
Sbjct: 4031 VCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRK 4090
Query: 1947 HSIPDACTLVLVKVCHPAMA---LPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQ 2003
C VL P ++ L F ++ K++ G + V + +++
Sbjct: 4091 FDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ-NRGNPAVSYVRVVTVAALGTNISIH 4149
Query: 2004 KGH--RVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTY 2061
K +V +N LP +SV + +++ G+QV +D N +++ +P++Y
Sbjct: 4150 KDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSY 4209
Query: 2062 YGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDP----SCQSLLVDEQQI 2117
+G VCG+CGN + ++ + P+ +A S + SW+ DP C+ +
Sbjct: 4210 HGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPED 4269
Query: 2118 PAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLY 2177
EQ E P G C + P + C + + F C +C GG
Sbjct: 4270 RLEQYEGP-GFC---------GPLSSGTGGP-FTTCHAHVPPESFFKGCVLDVCMGGGDR 4318
Query: 2178 QALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEG 2237
LC+AL ++ A CQ+ G+ WR C + CP S Y C P C SC
Sbjct: 4319 DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTP 4378
Query: 2238 AKVPSACAEGCICQPGYVLSEDKCVP-RSQCGCKDAHGGSIPLGKS-WVSSGCTEKCVC- 2294
A C EGC C G+VLS D+CVP + CGC A+G G W C++ C C
Sbjct: 4379 AVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADGTCSQWCRCG 4437
Query: 2295 -TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRM 2353
GG++ C C G C L + C + +C +GDP Y+T DG + QG
Sbjct: 4438 PGGGSLVCTPASCGLGEVCGLLPSGQH-GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTC 4496
Query: 2354 TYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQA--GLELVVN 2411
Y+L P G E V N+ ++ + + V +Y + + L A +L V+
Sbjct: 4497 EYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 4556
Query: 2412 NQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNY 2471
+A+P++ + L L G + + T L ++F G + +P+ Y + GLCGNY
Sbjct: 4557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 4616
Query: 2472 DKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQV 2531
+++ +D+ G W+V +G G +
Sbjct: 4617 NQDPADDLKAVGGKPA--------GWQV--------------GGAQGCGECVSKPC---P 4651
Query: 2532 SECSPEQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQD------PR 2584
S C+PEQ S AC V++ GP A CH V P + + C+LD C Q P
Sbjct: 4652 SPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPA 4711
Query: 2585 EQEEL-RCQVLSGH------------GVSSRYHISELYDTLPSILCQPGRPRGLRGPLRG 2631
+ CQ + H D+ P P G R
Sbjct: 4712 VATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACRE 4771
Query: 2632 RLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLT-EDCSQRCTCASSRILLC-EPF 2689
L P+ CGC +G YY LG F +C +RC C + C E
Sbjct: 4772 GCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGA 4831
Query: 2690 SCRAGEVCTLGNHTQGC 2706
+C E C L + Q C
Sbjct: 4832 ACGPHEECRLEDGVQAC 4848
Score = 850 bits (2195), Expect = 0.0
Identities = 567/1783 (31%), Positives = 796/1783 (44%), Gaps = 161/1783 (9%)
Query: 1044 CPPNARYESCA--CPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
CPPN+ YE CA C C S P C C EGC C+ GFL++ C+ C C++N
Sbjct: 1532 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 1591
Query: 1100 DYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGC---HPYAGT--- 1153
YYEP NC + C C G + CQ C VCQ G C P G
Sbjct: 1592 VYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCR 1651
Query: 1154 -------------------ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C-GNSTDP 1192
ATC ++GDPHY +FDGR F F G C Y+LA C G ST
Sbjct: 1652 PQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQG 1711
Query: 1193 F--FRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR--RTLVGGQQVTLPAIPSKG- 1247
F VT KN+ +G VS + V V + +++ K + V G LP + G
Sbjct: 1712 LTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGR 1771
Query: 1248 --VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKL 1305
V GAS L +FGL+V +D + ++ VT+ S+Y G +CGLCGN D N +ND +
Sbjct: 1772 ISVTQGASKAL--LVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 1829
Query: 1306 DGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVD-THGP 1364
+G+ A G SW+ D C + P+C GPGFCG L T GP
Sbjct: 1830 NGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGP 1888
Query: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
F TC HV SFF C+LD+C G + +LC +++ CQ AG ++ WR C +
Sbjct: 1889 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 1948
Query: 1425 ACPPNSKYSLCAKPCPDTCHSGF---SGMFCSDRCVEACECNPGFVLSGLECIPRSQ-CG 1480
CP NS Y +C PCP +C S + C CVE C+C+ GFVLS C+P + CG
Sbjct: 1949 TCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG 2008
Query: 1481 CLHPAGSYFKVGERWYKPG-CKELCVC-ESNNRIRCQPWRCRAQEFCGQ-QDGIYGCHAQ 1537
C G+Y + G ++ G C + C C + C P C E CG G +GC
Sbjct: 2009 CW-ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPV 2067
Query: 1538 GAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSY-FVVSATNENRGGILEV 1596
A C A GDPHY+T DG +F GTC Y+L+ PC + F V+ NE+RG V
Sbjct: 2068 STAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAV 2126
Query: 1597 SYIKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654
SY ++V + +++ S++L K+ ++G V LP L + LS V++ T GL
Sbjct: 2127 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQL-DSLLHAHLSGADVVVTTTSGL 2185
Query: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714
+ +DG V + VP++Y G LCGLCGNYN + DD K AG Q+G A E
Sbjct: 2186 SLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--WQVGGAQGCGEC 2243
Query: 1715 SEPGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
C PS C + C ++ GP + CH +VPP F C+ C
Sbjct: 2244 VSKPC------PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 2297
Query: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
+G LC ++ Y + C AG Q WR FCP +CP S Y C CP +C S+
Sbjct: 2298 QVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSL 2357
Query: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
+ P C A C E C C G +LSG +CVP+GQCGC Y+P+G+ +Y C L
Sbjct: 2358 SAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHD-DRYYPLGQTFYPGPGCDSL 2414
Query: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
C C ++C S+C P++ C G L C A G CQ G+ HY +FDG
Sbjct: 2415 CRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGT 2474
Query: 1953 CTLVLVKVCHPAMALPFFKISAKHEK-EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLIN 2011
C VL + C L F + ++ G R+ V + + ++ Q+ +V +N
Sbjct: 2475 CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE-QRQWKVTVN 2533
Query: 2012 SKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGN 2071
+ LP + + ++ G++V +D + + + +P YY +CG+CGN
Sbjct: 2534 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGN 2593
Query: 2072 FNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRA 2131
+N + +D+ P+ A + +EF NSW++ D C L P + PS C
Sbjct: 2594 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC---LPPPTCPPGSEGCIPSEEC-P 2649
Query: 2132 ADLRRAREKCE--AALRAPVW--AQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAF 2187
+L + +K E L +P + C +D L DC LC GG LC + A+
Sbjct: 2650 PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAY 2709
Query: 2188 GATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEG 2247
+ CQ+ G + WRN +FCP+ECP S Y C +CS C L + P CAEG
Sbjct: 2710 VSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQ---CPDGCAEG 2766
Query: 2248 CICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVC-TGGAIQCGDFRC 2306
C C G++ + CVP QCGC +G ++ + C ++C C G + C + C
Sbjct: 2767 CQCDSGFLYNGQACVPIQQCGCYH-NGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC 2825
Query: 2307 PSGSHCQLTS------------------------DNSNSNCVSDKSEQCSVYGDPRYLTF 2342
G CQ + C+ + C ++GDP Y +F
Sbjct: 2826 KPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSF 2885
Query: 2343 DGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV 2400
DG + QG YVL T V +G+ P V +N+ + +++ V G +
Sbjct: 2886 DGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNI 2945
Query: 2401 QLQAGL--ELVVNNQKMAVPYRPNE-HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLP 2457
+ ++ VN A+P + + VT + LV DF L VS+ ++LP
Sbjct: 2946 SIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLP 3005
Query: 2458 SMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEE 2517
S Y G V GLCGN D+N ND + P+G L ++ +G SW D L +E
Sbjct: 3006 SSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL--------CWDE 3057
Query: 2518 GQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLA-DPQGPFAACHQTVAPEPFQEHCVL 2575
+G+ C ++L C LA GPF CH V PE F + CVL
Sbjct: 3058 CRGS---------CPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVL 3108
Query: 2576 DLCSAQDPRE-------------------QEELRCQVLSGHGVSSRYHISELYDTLPSIL 2616
D+C R+ E+ R QV H P+
Sbjct: 3109 DVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASC 3168
Query: 2617 CQPG---RPRGLRGPLRGRLRQHPRLCLQWHPEPPLAD-CGCTSNGIYYQLGSSFLTE-D 2671
P P GP + L PL + CGC +NG Y++ GS F +
Sbjct: 3169 PSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGT 3228
Query: 2672 CSQRCTCA-SSRILLCEPFSCRAGEVCTL---GNHTQGCFPES 2710
CSQ C C L+C P SC GEVC L G H GC P S
Sbjct: 3229 CSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH--GCQPVS 3269
Score = 842 bits (2176), Expect = 0.0
Identities = 552/1779 (31%), Positives = 789/1779 (44%), Gaps = 140/1779 (7%)
Query: 1017 MSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESC--ACPASCK---SPRPSCGPLCR 1071
+S +A + + +G + + CP N+RYE C ACP SC +P G C
Sbjct: 718 LSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCV 777
Query: 1072 EGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQI 1129
EGCVC PGF+ S C+ ASSC C + PG E W C C C + +V C+
Sbjct: 778 EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 837
Query: 1130 SQ-CGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCG- 1187
Q C C ++NG GC+P TC GDPHYV+FDGR F FMG CTY+L CG
Sbjct: 838 KQSCPAGERCSVQNGLLGCYP-DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQ 896
Query: 1188 NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLK--GRRTLVGGQQVTLPAIPS 1245
N+ P FRV +NE +G + VS V V V + + + LV LP +
Sbjct: 897 NAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAA 956
Query: 1246 KG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLK 1304
G V + GR ++T+FGL V +D + ++ V S+Y+ LCGLCGN++G+ +D
Sbjct: 957 DGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLAL 1016
Query: 1305 LDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP 1364
G A + GNSWQ ++ C + + P DS + + CG L D GP
Sbjct: 1017 RGGGQAANALAFGNSWQ--EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGP 1074
Query: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
F C + C+ D C G LC ++T CQ AG V PWR CP+
Sbjct: 1075 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL 1134
Query: 1425 ACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
+CPP+S Y C+ CP +C C C E C C+ GF LSG C+P + CGC+H
Sbjct: 1135 SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVH- 1193
Query: 1485 AGSYFKVGERWYK-PGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCT 1543
G+Y G+ +Y PGC LC C+ + C+ C E C G GC A G++TC
Sbjct: 1194 QGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQ 1253
Query: 1544 ASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAV 1602
ASGDPHY TFDG FMGTC YVL + C +R F V N G G + V+ + V
Sbjct: 1254 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 1313
Query: 1603 HVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSH 1662
V F L + R KV +NG + LPV LA G++ + V++ T+FGL+V YD +
Sbjct: 1314 QVANFTLRLE-QRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVY 1372
Query: 1663 LVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWK--LPES------ 1714
V VTVP +Y Q+CGLCGNYN + DD +P+ AG++ + G +W+ +P+S
Sbjct: 1373 YVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT 1432
Query: 1715 -SEPG---CFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVH 1770
PG C P ++ + + C +L +P GP S CH++V PQ C+
Sbjct: 1433 PCPPGSEDCIPSHKCPPELEKKYQKEEF---CGLLSSPTGPLSSCHKLVDPQGPLKDCIF 1489
Query: 1771 GQCGTKGDTTALCRSLQAYASLC-AQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTC 1829
C G+ + LC ++ AY S C A G WR TFCPM CPP S Y C+ C C
Sbjct: 1490 DLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC 1549
Query: 1830 SSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTC 1889
S+++ P C CAE C+C G + +G +CVP+ QCGC Y P E+ + C
Sbjct: 1550 SALSAPPQCQDG--CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEP--EQTVLIDNC 1605
Query: 1890 TRLCTCSVHNNITCFQSTCKPNQICWALDGLLRC------------------RASGVGV- 1930
+ CTC + C + +CKP Q+C G+L C G GV
Sbjct: 1606 RQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVC 1665
Query: 1931 -------CQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMA---LPFFKISAKHEKEE 1980
C L G+ HY SFDG C VL P ++ L F ++ K++
Sbjct: 1666 LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ-NR 1724
Query: 1981 GGTEAFRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038
G + V + +++ K +V +N LP +SV + +++
Sbjct: 1725 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV 1784
Query: 2039 IKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSW 2098
G+QV +D N +++ +P++Y+G VCG+CGN + ++ + P+ +A S + SW
Sbjct: 1785 ADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW 1844
Query: 2099 KDKDIDP----SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCA 2154
+ DP C+ + EQ E P G C A + C
Sbjct: 1845 RAPGWDPLCWDECRGSCPTCPEDRLEQYEGP-GFCGPL----------APGTGGPFTTCH 1893
Query: 2155 SRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAY 2214
+ + F C +C GG LC+AL ++ A CQ+ G+ WR C + CP
Sbjct: 1894 AHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPEN 1953
Query: 2215 SSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVP-RSQCGCKDAH 2273
S Y C C SC A C EGC C G+VLS D+CVP + CGC A+
Sbjct: 1954 SHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW-AN 2012
Query: 2274 GGSIPLGKS-WVSSGCTEKCVC--TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQ 2330
G G W C++ C C GG++ C C G C L + C + +
Sbjct: 2013 GTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH-GCQPVSTAE 2071
Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
C +GDP Y+T DG + QG Y+L P G E V N+ ++ + +
Sbjct: 2072 CQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 2131
Query: 2391 VITTVYGYKVQLQA--GLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGG 2448
V +Y + + L A +L V+ + +P++ + L L G + + T L ++F G
Sbjct: 2132 VTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2191
Query: 2449 RKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRF 2508
+ +P+ Y G + GLCGNY+++ +D+ G W+V
Sbjct: 2192 DSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA--------GWQV--------- 2234
Query: 2509 PRAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLADPQGPFAACHQTVAPE 2567
+G G + S C+PEQ S AC V++ GP A CH V P
Sbjct: 2235 -----GGAQGCGECVSKPC---PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPA 2286
Query: 2568 PFQEHCVLDLCSAQD-------------------PREQEELRCQVLSGHGVSSRYHISEL 2608
+ + C+LD C Q + E R + H
Sbjct: 2287 QYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELC 2346
Query: 2609 YDTLPSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFL 2668
D+ P P G R L P+ CGC + YY LG +F
Sbjct: 2347 GDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFY 2406
Query: 2669 T-EDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGC 2706
C C C + CEP SC E C + GC
Sbjct: 2407 PGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGC 2445
Score = 838 bits (2165), Expect = 0.0
Identities = 566/1783 (31%), Positives = 792/1783 (44%), Gaps = 161/1783 (9%)
Query: 1044 CPPNARYESCA--CPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
CP N+ YE CA C C S C C EGC C+ GFL++ C+ C C++N
Sbjct: 2733 CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 2792
Query: 1100 DYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGC---HPYAGT--- 1153
YYEP NC + C C G V CQ C VCQ G C P G
Sbjct: 2793 AYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCR 2852
Query: 1154 -------------------ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C-GNSTDP 1192
ATC ++GDPHY +FDGR F F G C Y+LA C G ST
Sbjct: 2853 PQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQG 2912
Query: 1193 F--FRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR--RTLVGGQQVTLPAIPSKG- 1247
F VT KN+ +G VS + V V + +++ K + V G LP + G
Sbjct: 2913 LTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGR 2972
Query: 1248 --VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKL 1305
V GAS L +FGL+V +D + ++ VT+ S+Y G +CGLCGN D N +ND +
Sbjct: 2973 ISVTQGASKAL--LVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 3030
Query: 1306 DGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVD-THGP 1364
+G+ A G SW+ D C + P+C GPGFCG L T GP
Sbjct: 3031 NGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGP 3089
Query: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
F TC HV SFF C+LD+C G + +LC +++ CQ AG ++ WR C +
Sbjct: 3090 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 3149
Query: 1425 ACPPNSKYSLCAKPCPDTCHSGF---SGMFCSDRCVEACECNPGFVLSGLECIPRSQ-CG 1480
CP NS Y +C PCP +C S + C CVE C+C+ GFVLS C+P + CG
Sbjct: 3150 TCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG 3209
Query: 1481 CLHPAGSYFKVGERWYKPG-CKELCVC-ESNNRIRCQPWRCRAQEFCGQ-QDGIYGCHAQ 1537
C G+Y + G ++ G C + C C + C P C E CG G +GC
Sbjct: 3210 CW-ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPV 3268
Query: 1538 GAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSY-FVVSATNENRGGILEV 1596
A C A GDPHY+T DG F GTC Y+L+ PC + F V+ NE+RG V
Sbjct: 3269 STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAV 3327
Query: 1597 SYIKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654
SY ++V + +++ S++L K+ ++G V LP L + LS V++ T GL
Sbjct: 3328 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQL-DSLLHAHLSGADVVVTTTSGL 3386
Query: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714
+ +DG V + VP++Y G LCGLCGNYN + DD K AG Q+G A E
Sbjct: 3387 SLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--WQVGGAQGCGEC 3444
Query: 1715 SEPGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
C PS C + C ++ GP + CH +VPP F C+ C
Sbjct: 3445 VSKPC------PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 3498
Query: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
+G LC ++ Y + C AG Q WR FCP +CP S Y C CP +C S+
Sbjct: 3499 QVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSL 3558
Query: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
+ P C A C E C C G +LSG +CVP+GQCGC Y+P+G+ +Y C L
Sbjct: 3559 SAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHD-DRYYPLGQTFYPGPGCDSL 3615
Query: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
C C ++C S+C P++ C G L C A G CQ G+ HY +FDG
Sbjct: 3616 CRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGT 3675
Query: 1953 CTLVLVKVCHPAMALPFFKISAKHEK-EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLIN 2011
C VL + C L F + ++ G R+ V + + ++ Q+ +V +N
Sbjct: 3676 CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE-QRQWKVTVN 3734
Query: 2012 SKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGN 2071
+ LP + + ++ G++V +D + + + +P YY +CG+CGN
Sbjct: 3735 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGN 3794
Query: 2072 FNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRA 2131
+N + +D+ P+ A + +EF NSW++ D C L P PS C
Sbjct: 3795 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC---LPPPTCPPGSAGCIPSDKC-P 3850
Query: 2132 ADLRRAREKCE--AALRAPVW--AQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAF 2187
+L + +K E L +P + C +D L DC LC GG LC + A+
Sbjct: 3851 PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAY 3910
Query: 2188 GATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEG 2247
+ CQ+ G WRN +FCP+ECP S Y C +CS C L + P CAEG
Sbjct: 3911 VSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQ---CPDGCAEG 3967
Query: 2248 CICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVC-TGGAIQCGDFRC 2306
C C G++ + CVP QCGC +G ++ + C ++C C G + C + C
Sbjct: 3968 CQCDSGFLYNGQACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC 4026
Query: 2307 PSGSHCQ--------LTSD----------------NSNSNCVSDKSEQCSVYGDPRYLTF 2342
G CQ +T D C+ + C ++GDP Y +F
Sbjct: 4027 KPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSF 4086
Query: 2343 DGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV 2400
DG + QG YVL T V +G+ P V +N+ + +++ V G +
Sbjct: 4087 DGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNI 4146
Query: 2401 QLQAGL--ELVVNNQKMAVPYRPNE-HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLP 2457
+ ++ VN A+P + + V + LV DF L VS+ ++LP
Sbjct: 4147 SIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLP 4206
Query: 2458 SMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEE 2517
S Y G V GLCGN D+N ND + P+G L ++ +G SW D L +E
Sbjct: 4207 SSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL--------CWDE 4258
Query: 2518 GQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLAD-PQGPFAACHQTVAPEPFQEHCVL 2575
+G+ C ++L C L+ GPF CH V PE F + CVL
Sbjct: 4259 CRGS---------CPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVL 4309
Query: 2576 DLCSAQDPRE-------------------QEELRCQVLSGHGVSSRYHISELYDTLPSIL 2616
D+C R+ E+ R QV H P+
Sbjct: 4310 DVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASC 4369
Query: 2617 CQPG---RPRGLRGPLRGRLRQHPRLCLQWHPEPPLAD-CGCTSNGIYYQLGSSFLTE-D 2671
P P GP + L PL + CGC +NG Y++ GS F +
Sbjct: 4370 PSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGT 4429
Query: 2672 CSQRCTCA-SSRILLCEPFSCRAGEVCTL---GNHTQGCFPES 2710
CSQ C C L+C P SC GEVC L G H GC P S
Sbjct: 4430 CSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH--GCQPVS 4470
Score = 817 bits (2111), Expect = 0.0
Identities = 533/1665 (32%), Positives = 763/1665 (45%), Gaps = 121/1665 (7%)
Query: 1127 CQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPC 1186
C+ QC CQ+ G+ GC + TA C GDPHY TFDGR + MG C+Y + + C
Sbjct: 444 CEGMQCAAGQRCQVVGGKAGCVAES-TAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 502
Query: 1187 G-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRR--TLVGGQQVTLPAI 1243
+ T P F V AKNE +G VS + V V +V+L +G LV Q+ LP
Sbjct: 503 SEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 562
Query: 1244 PSKG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDH 1302
S+G + + SG ++ FGL V +D D QL +++ + + ++CGLCGNY+G+ +D
Sbjct: 563 LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 622
Query: 1303 LKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTH 1362
L DG+ A D E +SW+ D D D C+ N P+C G CG L
Sbjct: 623 LTPDGALAPDAVEFASSWKLD-DGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 681
Query: 1363 GPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFC 1422
GPF C + F + C+ D+C G + LC +S C + G +V WR P C
Sbjct: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
Query: 1423 PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR-CVEACECNPGFVLSGLECIPRSQCGC 1481
P++CP NS+Y LC CP +C+ + CS R CVE C C PGFV SG C+P S CGC
Sbjct: 742 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801
Query: 1482 LHPAGSYFKVGERWYKPGCKELCVCE-SNNRIRCQPWR-CRAQEFCGQQDGIYGCHAQGA 1539
E W C+ C C + +++ C+ + C A E C Q+G+ GC+
Sbjct: 802 TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 861
Query: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYI 1599
TC SGDPHY++FDG FMGTCTY+L C + F V NE+RG VSY
Sbjct: 862 GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGS-QTVSYT 920
Query: 1600 KAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVR 1657
+AV V + +++ R +V+++ LP A G+V + ++ T+FGL V
Sbjct: 921 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 980
Query: 1658 YDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEP 1717
YD + V VPSSY LCGLCGN+N + DD A +++ G +W+ E + P
Sbjct: 981 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ--EETRP 1038
Query: 1718 GCFLVGGKPSSCQENSMADA---WNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
GC +P C + A +KN C IL +P+GPF +CH + PQ + CV+ +C
Sbjct: 1039 GCGAT--EPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRC 1096
Query: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
G + LC +L YA+ C AG WR+ CP+ CPP S Y CS CP +C +
Sbjct: 1097 LLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDL 1156
Query: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
P C C E C C +G LSG SC+PL CGC G+YHP G+ +Y C L
Sbjct: 1157 PVPGGC--GSECHEGCVCDEGFALSGESCLPLASCGCVH-QGTYHPPGQTFYPGPGCDSL 1213
Query: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
C C ++C S+C P++ C G L C A G CQ G+ HY +FDG
Sbjct: 1214 CHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGT 1273
Query: 1953 CTLVLVKVCHPAMALPFFKISAKHEK-EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLIN 2011
C VL + C L F + ++ G R+ V + + ++ Q+ +V +N
Sbjct: 1274 CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE-QRQWKVTVN 1332
Query: 2012 SKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGN 2071
+ LP + + ++ G++V +D + + + +P YY ++CG+CGN
Sbjct: 1333 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGN 1392
Query: 2072 FNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRA 2131
+N + +D+ P+ A + +EF NSW++ D C L P + PS C
Sbjct: 1393 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC---LPPTPCPPGSEDCIPSHKC-P 1448
Query: 2132 ADLRRAREKCE--AALRAPV--WAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAF 2187
+L + +K E L +P + C +D L DC LC GG LC + A+
Sbjct: 1449 PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAY 1508
Query: 2188 GATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDG--RCEGAKVPSACA 2245
+ CQ+ G WR +FCP+ECP S Y C +CS C L +C+ CA
Sbjct: 1509 VSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQ-----DGCA 1563
Query: 2246 EGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVC-TGGAIQCGDF 2304
EGC C G++ + CVP QCGC +G ++ + C ++C C G + C +
Sbjct: 1564 EGCQCDSGFLYNGQACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH 1622
Query: 2305 RCPSGSHCQ--------LTSD----------------NSNSNCVSDKSEQCSVYGDPRYL 2340
C G CQ +T D C+ + C ++GDP Y
Sbjct: 1623 SCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYH 1682
Query: 2341 TFDGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGY 2398
+FDG + QG YVL T V +G+ P V +N+ + +++ V G
Sbjct: 1683 SFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGT 1742
Query: 2399 KVQLQAGL--ELVVNNQKMAVPYR-PNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVIS 2455
+ + ++ VN A+P + + VT + LV DF L VS+ ++
Sbjct: 1743 NISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVT 1802
Query: 2456 LPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
LPS Y G V GLCGN D+N ND + P+G L ++ +G SW D L
Sbjct: 1803 LPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL--------CW 1854
Query: 2516 EEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLA-DPQGPFAACHQTVAPEPFQEHC 2573
+E +G+ C ++L C LA GPF CH V PE F + C
Sbjct: 1855 DECRGS---------CPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGC 1905
Query: 2574 VLDLCSAQDPRE-------------------QEELRCQVLSGHGVSSRYHISELYDTLPS 2614
VLD+C R+ E+ R QV H P+
Sbjct: 1906 VLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPA 1965
Query: 2615 ILCQPG---RPRGLRGPLRGRLRQHPRLCLQWHPEPPLAD-CGCTSNGIYYQLGSSFLTE 2670
P P GP + L PL + CGC +NG Y++ GS F +
Sbjct: 1966 SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWAD 2025
Query: 2671 -DCSQRCTCA-SSRILLCEPFSCRAGEVCTL---GNHTQGCFPES 2710
CSQ C C L+C P SC GEVC L G H GC P S
Sbjct: 2026 GTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH--GCQPVS 2068
Score = 745 bits (1923), Expect = 0.0
Identities = 482/1502 (32%), Positives = 696/1502 (46%), Gaps = 120/1502 (7%)
Query: 1044 CPPNARYESCA--CPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
CP N+ YE CA C C S C C EGC C+ GFL++ C+ C C++N
Sbjct: 3934 CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 3993
Query: 1100 DYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGC---HPYAGT--- 1153
YYEP NC + C C G V CQ C VCQ G C P G
Sbjct: 3994 VYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCR 4053
Query: 1154 -------------------ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C-GNSTDP 1192
ATC ++GDPHY +FDGR F F G C Y+LA C G ST
Sbjct: 4054 PQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQG 4113
Query: 1193 F--FRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR--RTLVGGQQVTLPAIPSKGV 1248
F VT KN+ +G VS + V V + +++ K + V G LP + G
Sbjct: 4114 LTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGR 4173
Query: 1249 FLGASGRFVELQT-EFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDG 1307
A G L +FGL+V +D + ++ VT+ S+Y G +CGLCGN D N +ND + +G
Sbjct: 4174 ISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG 4233
Query: 1308 SPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVD-THGPFE 1366
+ A G SW+ D C + P+C GPGFCG L T GPF
Sbjct: 4234 TLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFT 4292
Query: 1367 TCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
TC HV SFF C+LD+C G + +LC +++ CQ AG ++ WR C + C
Sbjct: 4293 TCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 4352
Query: 1427 PPNSKYSLCAKPCPDTCHSGF---SGMFCSDRCVEACECNPGFVLSGLECIPRSQ-CGCL 1482
P NS Y +C PCP +C S + C CVE C+C+ GFVLS C+P + CGC
Sbjct: 4353 PENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW 4412
Query: 1483 HPAGSYFKVGERWYKPG-CKELCVC-ESNNRIRCQPWRCRAQEFCGQ-QDGIYGCHAQGA 1539
G+Y + G ++ G C + C C + C P C E CG G +GC
Sbjct: 4413 -ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVST 4471
Query: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSY-FVVSATNENRGGILEVSY 1598
A C A GDPHY+T DG F GTC Y+L+ PC + F V+ NE+RG VSY
Sbjct: 4472 AECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSY 4530
Query: 1599 IKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQV 1656
++V + +++ S++L K+ ++G VALP L + LS V++ T GL +
Sbjct: 4531 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVVTTTSGLSL 4589
Query: 1657 RYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSE 1716
+DG V + VP++Y LCGLCGNYN + DD K AG Q+G A E
Sbjct: 4590 AFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--WQVGGAQGCGECVS 4647
Query: 1717 PGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGT 1775
C PS C + C ++ GP + CH +VPP F C+ C
Sbjct: 4648 KPC------PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQV 4701
Query: 1776 KGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINN 1834
+G LC ++ Y + C AG Q WR FCP++CP S Y C CP +C S++
Sbjct: 4702 QGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSA 4761
Query: 1835 PRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCT 1894
P C A C E C C G +LSG +CVP+GQCGC G Y+P+GE +Y C R C
Sbjct: 4762 PEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERRCE 4818
Query: 1895 CSVHNNITCFQ-STCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDAC 1953
C ++TC + + C P++ C DG+ C A+G G C G HY++ DG + + +C
Sbjct: 4819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSC 4878
Query: 1954 TLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSK 2013
+ VL +VCHP F I EK G L + + + V+L +G +V ++ +
Sbjct: 4879 SYVLAQVCHPKPGDEDFSIVL--EKNAAGD----LQRLLVTVAGQVVSLAQGQQVTVDGE 4932
Query: 2014 QVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFN 2073
V LP + V V + ++ G+++ FDG+ L + IP+ + G++CG+CGNFN
Sbjct: 4933 AVALPVA--VGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFN 4990
Query: 2074 DEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQS--------LLVDEQQIPAEQQENP 2125
D+ ++P+ A+S F +W+ C + + E+ P E E
Sbjct: 4991 GNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNE-- 5048
Query: 2126 SGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQ 2185
LR + +A C + + + + C LC G LC++L
Sbjct: 5049 ----ACGQLRNPQGP---------FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLA 5095
Query: 2186 AFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACA 2245
A+ A CQ+ G+ WR SFCPL CPA+S Y+ C +C SC L G + C
Sbjct: 5096 AYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL---TGCTTRCF 5152
Query: 2246 EGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGA-IQCGDF 2304
EGC C ++LS+ C+P CGC +G +P+ S ++S C+E+C C+ + + C
Sbjct: 5153 EGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAA 5211
Query: 2305 RCPSGSHCQLTSDNSN-----SNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIK 2359
CP G C++ ++ N CV + + R T Y L R L
Sbjct: 5212 GCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP-GLQN 5270
Query: 2360 TVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMA--- 2416
T+ E + G+ + + IF Q+ + T+ K GL + + +K+A
Sbjct: 5271 TIPWYRVVAEVQICHGKTEA-VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVS 5329
Query: 2417 VPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRK 2476
V P+ L V + V G + + + + G + G CGN+D ++
Sbjct: 5330 VSRTPDGSLLVR---------QKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQT 5380
Query: 2477 ND 2478
ND
Sbjct: 5381 ND 5382
Score = 646 bits (1667), Expect = 0.0
Identities = 392/1088 (36%), Positives = 549/1088 (50%), Gaps = 63/1088 (5%)
Query: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
CP N+ YE C CPASC SP P P C EGC C+ GF+ S + C+ ++ C C
Sbjct: 4352 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 4411
Query: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
+ N Y+E G+E W C++ CRC PG + C + CG VC L +GQ+GC P +
Sbjct: 4412 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 4470
Query: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
TA C +GDPHYVT DG F F G C Y+L+ PC F VT NE +G + VS
Sbjct: 4471 TAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 4530
Query: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
V + + ++TL R+ V G V LP + SG V + T GL +
Sbjct: 4531 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLA 4590
Query: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
+DGD + + V + Y+ LCGLCGNY+ + +D + G PAG WQ Q
Sbjct: 4591 FDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 4640
Query: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
C + PS C Q S GP CG + T GP C V A +F C+LD C
Sbjct: 4641 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 4700
Query: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
QG LC ++T CQ AG + WR P FCP+ CP +S Y LC CP +C S
Sbjct: 4701 VQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLS 4760
Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
+ C C E C C+ GFVLSG C+P QCGCLH G Y+ +GE +Y P C+ C C
Sbjct: 4761 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERRCEC 4819
Query: 1507 ESNNRIRCQPW-RCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCT 1565
+ CQ C E C +DG+ CHA G C A+G HY+T DG ++ G+C+
Sbjct: 4820 GPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCS 4879
Query: 1566 YVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
YVL + C + D F + +N G L+ + VTV +SL +G +V ++G
Sbjct: 4880 YVLAQVCHPKPGDEDFSI-VLEKNAAGDLQ-----RLLVTVAGQVVSLAQGQQVTVDGEA 4933
Query: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
VALPV A GRV + ++L T GL++ +DG + +++PS + G+LCGLCGN+N
Sbjct: 4934 VALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNG 4991
Query: 1686 NSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSC----QENSMADAWNKN 1741
N DD + P+ A GAAW+ P SS+ GC G P C E + N+
Sbjct: 4992 NWSDDFVLPNGSAASSVETFGAAWRAPGSSK-GCG-EGCGPQGCPVCLAEETAPYESNEA 5049
Query: 1742 CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-P 1800
C L NPQGPF+ C V+ P F CV+ C KGD LCRSL AY + C AG A
Sbjct: 5050 CGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVK 5109
Query: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860
WR +FCP+ CP S YS C+ C +C++++ C C E CEC +LS
Sbjct: 5110 PWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGC--TTRCFEGCECDDRFLLSQGV 5167
Query: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920
C+P+ CGCT G Y PV T + C+ C+CS + +TC + C P ++C
Sbjct: 5168 CIPVQDCGCTH-NGRYLPVNSSLLTSD-CSERCSCSSSSGLTCQAAGCPPGRVCEVKAEA 5225
Query: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAM--ALPFFKISAKHEK 1978
C A+ G+C L ++ +FDG+ + L C P + +P++++ A+ +
Sbjct: 5226 RNCWATR-GLCVLSVGANLTTFDGARGATTSPGVYELSSRC-PGLQNTIPWYRVVAEVQI 5283
Query: 1979 EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYS-IV 2037
G TEA + +V+I D VTL V +N +V LPA ++ VSV + S +V
Sbjct: 5284 CHGKTEA--VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPA-EKLASVSVSRTPDGSLLV 5340
Query: 2038 NIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
K GVQV N + + + + GK+CG CGNF+ ++ ++ ++ A +
Sbjct: 5341 RQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPA------MEK 5394
Query: 2098 WKDKDIDP 2105
W+ +D P
Sbjct: 5395 WRAQDFSP 5402
Score = 597 bits (1539), Expect = e-170
Identities = 392/1267 (30%), Positives = 580/1267 (45%), Gaps = 93/1267 (7%)
Query: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCW 1573
C+ +C A + C G GC A+ A C A GDPHY TFDG + MGTC+Y + C
Sbjct: 444 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 503
Query: 1574 SRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCK--VMLNGHRVALPVW 1631
F V A NE+RG VSY+ V V + S+SL RG V+++ R LPV
Sbjct: 504 EDDTLPAFSVEAKNEHRGS-RRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 562
Query: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDN 1691
L++GR+ + S ++ FGL V YD + +++P+ + Q+CGLCGNYN + DD
Sbjct: 563 LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 622
Query: 1692 LRPDRKLAGDSMQLGAAWKLPESS---EPGCFLVGGKPSSCQENSMADAWNKNCAILINP 1748
L PD LA D+++ ++WKL + E GC P+ + ++ C +L
Sbjct: 623 LTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTKL 680
Query: 1749 QGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPA-WRNRTF 1807
GPF+ CH + P+ CV+ C G+ +LCR L AYA C + G + WR+
Sbjct: 681 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 740
Query: 1808 CPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC 1867
CP+ CP S Y C CP +C+ P +C PC E C C G + SG +CVP C
Sbjct: 741 CPLSCPANSRYELCGPACPTSCNGAAAPSNC-SGRPCVEGCVCLPGFVASGGACVPASSC 799
Query: 1868 GCTDPAGSYHPVGERWYTENTCTRLCTCS-VHNNITCF-QSTCKPNQICWALDGLLRCRA 1925
GCT P E W E C R CTC+ + +TC + +C + C +GLL C
Sbjct: 800 GCTFQGLQLAPGQEVWADE-LCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 858
Query: 1926 SGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEA 1985
G CQ G+ HYVSFDG CT +LV C ALP F++ ++E T +
Sbjct: 859 DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS 918
Query: 1986 FRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGV 2043
+ V ++ +V +++ + +VL++ LP + V V ++V G+
Sbjct: 919 YT-RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGL 977
Query: 2044 QVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDI 2103
V +D N + ++P++Y +CG+CGNFN + D+L + A + F NSW++ +
Sbjct: 978 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQE-ET 1036
Query: 2104 DPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCE--AALRAPVWAQCASRIDLTP 2161
P C + E + P + A +++ +C A + P + +C S++D
Sbjct: 1037 RPGCGA---------TEPGDCPKLDSLVAQQLQSKNECGILADPKGP-FRECHSKLDPQG 1086
Query: 2162 FLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCL 2221
+ DC C G LC AL + A CQ+ G WR+ CPL CP +S Y C
Sbjct: 1087 AVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACS 1146
Query: 2222 PSCSPSCWDLD--GRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSI-P 2278
C SC DL G C S C EGC+C G+ LS + C+P + CGC H G+ P
Sbjct: 1147 YGCPLSCGDLPVPGGCG-----SECHEGCVCDEGFALSGESCLPLASCGC--VHQGTYHP 1199
Query: 2279 LGKSWVSS-GCTEKCVCT-GGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGD 2336
G+++ GC C C GG + C C CQ + CV+ S C GD
Sbjct: 1200 PGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQ--PSGGSLGCVAVGSSTCQASGD 1257
Query: 2337 PRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITT-V 2395
P Y TFDG + G YVL +T P G+ V N + + + VIT V
Sbjct: 1258 PHYTTFDGRRFDFMGTCVYVLAQTCGTRP-GLHRFAVLQEN-VAWGNGRVSVTRVITVQV 1315
Query: 2396 YGYKVQL-QAGLELVVNNQKMAVPY-RPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAV 2453
+ ++L Q ++ VN M +P N +R + G + + TDF L V++
Sbjct: 1316 ANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVR 1375
Query: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513
+++P Y + GLCGNY+ + K+D P+G+ N N FGNSWE D+ P P
Sbjct: 1376 VTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCP 1435
Query: 2514 AEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVLADPQGPFAACHQTVAPEPFQEH 2572
G + +C PE + + C +L+ P GP ++CH+ V P+ +
Sbjct: 1436 P---------GSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 1486
Query: 2573 CVLDLCSAQDPRE-------QEELRCQVLSGHGVSSRY------------HISELYDTLP 2613
C+ DLC CQ GH R H DT
Sbjct: 1487 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCS 1546
Query: 2614 ---SIL-----CQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGS 2665
S L CQ G G + + + C+ P+ CGC NG+YY+
Sbjct: 1547 LGCSALSAPPQCQDGCAEGCQ--CDSGFLYNGQACV------PIQQCGCYHNGVYYEPEQ 1598
Query: 2666 SFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQCRE 2725
+ L ++C Q+CTC + + ++C+ SC+ G+VC C + PC C+ C+E
Sbjct: 1599 TVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKE 1658
Query: 2726 QGATFTC 2732
QG C
Sbjct: 1659 QGGQGVC 1665
Score = 376 bits (965), Expect = e-103
Identities = 221/659 (33%), Positives = 316/659 (47%), Gaps = 25/659 (3%)
Query: 1043 RCPPNARYESC--ACPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
+CP ++ YE C +CP SC S C CREGCVC+ GF+ S + C+ C C ++
Sbjct: 4738 QCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 4797
Query: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQI-SQCGTHTVCQLKNGQYGCHPYAGTATC 1156
YY G ++ P C C C PG V CQ + CG H C+L++G CH G C
Sbjct: 4798 GRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHA-TGCGRC 4856
Query: 1157 LVYGDPHYVTFDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQEGVSCLSKVY 1215
L G HY+T DGR + G C+Y+LAQ C D F + + G L ++
Sbjct: 4857 LANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLL 4911
Query: 1216 VTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQL 1275
VT+ V+L +G++ V G+ V LP + V + A GR + LQT GLR+ +DGD L
Sbjct: 4912 VTVAGQVVSLAQGQQVTVDGEAVALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGDAHL 4970
Query: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQV 1335
+++ S + G+LCGLCGN++GN +D + +GS A E G +W+ +
Sbjct: 4971 LMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGP 5030
Query: 1336 VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLL 1395
P C + + CG+L + GPF TC + + +F C+ D+C +G + L
Sbjct: 5031 QGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFL 5090
Query: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH--SGFSGMFCS 1453
C ++ T CQ AG AVKPWR FCP+ CP +S YS+C + C +C SG +G C+
Sbjct: 5091 CRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG--CT 5148
Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIR 1513
RC E CEC+ F+LS CIP CGC H G Y V C E C C S++ +
Sbjct: 5149 TRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSSSGLT 5207
Query: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPC- 1572
CQ C C + C A C S + TFDGA Y L+ C
Sbjct: 5208 CQAAGCPPGRVCEVKAEARNCWAT-RGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP 5266
Query: 1573 -WSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVW 1631
+ Y VV+ G + + VH+ D ++L V +NG RV LP
Sbjct: 5267 GLQNTIPWYRVVAEVQICHG---KTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAE 5323
Query: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
R +L+ G+QV + V V V + + G+LCG CGN++ + +D
Sbjct: 5324 KLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 5382
Score = 323 bits (829), Expect = 1e-87
Identities = 235/847 (27%), Positives = 357/847 (42%), Gaps = 87/847 (10%)
Query: 1902 TCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVC 1961
+C C Q C + G C A VC+ G+ HY +FDG + + C+ +V++C
Sbjct: 443 SCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 502
Query: 1962 HPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPA 2019
LP F + AK+E G + V + Y V+L +G VL+++++ LP
Sbjct: 503 SEDDTLPAFSVEAKNE-HRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 561
Query: 2020 ISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDE 2079
+ V S ++V + G+ V +D + L + +P + +VCG+CGN+N + D+
Sbjct: 562 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 621
Query: 2080 LMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPA---EQQENPSGNCRAADLRR 2136
+ P +A EF +SWK D D C+ + PA Q ++ G+ L +
Sbjct: 622 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTK 679
Query: 2137 AREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGL 2196
L P +A C +D PFL C LC GG +LC+ L A+ C G+
Sbjct: 680 --------LDGP-FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGI 730
Query: 2197 KPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPS-----ACAEGCICQ 2251
WR+ + CPL CPA S Y C P+C S C GA PS C EGC+C
Sbjct: 731 SVGDWRSPANCPLSCPANSRYELCGPACPTS-------CNGAAAPSNCSGRPCVEGCVCL 783
Query: 2252 PGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGA--IQCGDFR-CPS 2308
PG+V S CVP S CGC P + W C +C C G + C D + CP+
Sbjct: 784 PGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPA 843
Query: 2309 GSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVD---VLP 2365
G C + N C D+ C GDP Y++FDG + G TY+L+ + LP
Sbjct: 844 GERCSV--QNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALP 901
Query: 2366 EGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE 2423
+LVE ++ S + + V G KV ++ +++V++ +P++ +
Sbjct: 902 --AFRVLVENEHRGSQTVS--YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAAD 957
Query: 2424 -HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLP 2482
++V G+ + TDF L V++ +PS Y + GLCGN++ + +D+ L
Sbjct: 958 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
Query: 2483 SGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASN 2542
G N FGNSW+ +T A E G +L Q+
Sbjct: 1018 GGGQAANALAFGNSWQEETRP-------GCGATEPGDCPKLDSLVAQQL----------Q 1060
Query: 2543 STQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSR 2602
S C +LADP+GPF CH + P+ CV D C P + L C L+ + + +
Sbjct: 1061 SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL--PGQSGPL-CDALATYAAACQ 1117
Query: 2603 YHISELY----DTLPSILCQPGR------------------PRGLRGPLRGRLRQHPRLC 2640
+ ++ + L + C P P G
Sbjct: 1118 AAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFA 1177
Query: 2641 LQWHPEPPLADCGCTSNGIYYQLGSSFLT-EDCSQRCTCASSRILLCEPFSCRAGEVCTL 2699
L PLA CGC G Y+ G +F C C C ++ CE SC E C
Sbjct: 1178 LSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQP 1237
Query: 2700 GNHTQGC 2706
+ GC
Sbjct: 1238 SGGSLGC 1244
>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
sapiens]
Length = 3003
Score = 876 bits (2264), Expect = 0.0
Identities = 568/1757 (32%), Positives = 818/1757 (46%), Gaps = 156/1757 (8%)
Query: 1044 CPPNARYESCA--CPASCKS-PRPS-CGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
CPP++ YE+C+ CP SC P P CG C EGCVC+ GF S C+ +SC C +
Sbjct: 1136 CPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQG 1195
Query: 1100 DYYEPGAEWF-SPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLV 1158
Y+ PG ++ P C C C G V C+ S CG H CQ G GC G++TC
Sbjct: 1196 TYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVA-VGSSTCQA 1254
Query: 1159 YGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPF-FRVTAKNEEQGQEGVSCLSKVYVT 1217
GDPHY TFDGR F FMG C Y+LAQ CG F V +N G VS + V
Sbjct: 1255 SGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQ 1314
Query: 1218 LPESTVTLLKGR-RTLVGGQQVTLPAIPSKGVFLGAS-GRFVELQTEFGLRVRWDGDQQL 1275
+ T+ L + + + V G + LP + + G + G V ++T+FGLRV +D +
Sbjct: 1315 VANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYV 1374
Query: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQ---- 1331
VTV Y ++CGLCGNY+G+ +D K +GS AG+ E GNSW+ + D C
Sbjct: 1375 RVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWE-EVVPDSPCLPPTP 1433
Query: 1332 ----KYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
+ S C L+ FCG L GP +C V C+ D+C
Sbjct: 1434 CPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL 1493
Query: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
G +LC+++ + CQ AG V+PWR FCPM CPPNS Y LCA C C +
Sbjct: 1494 GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALS 1553
Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCE 1507
+ C D C E C+C+ GF+ +G C+P QCGC H G Y++ + C++ C C
Sbjct: 1554 APPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHN-GVYYEPEQTVLIDNCRQQCTCH 1612
Query: 1508 SNNRIRCQPWRC--------------------------RAQEFCGQQDGIYGCHAQGAAT 1541
+ + CQ C R QE C +Q G C AT
Sbjct: 1613 AGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEAT 1672
Query: 1542 CTASGDPHYLTFDGALHHFMGTCTYVLTR---PCWSRSQDSYFVVSATNENRGGILEVSY 1598
C GDPHY +FDG F GTC YVL P S + F V+ N+NRG VSY
Sbjct: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPA-VSY 1731
Query: 1599 IKAVHVTVFDLSISLLRG----CKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654
++ V V +IS+ + +V +NG ALPV +A GR+++ ++ LL +FGL
Sbjct: 1732 VRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGL 1791
Query: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714
QV YD + V+VT+PSSY G +CGLCGN + N +D + P+ LA G +W+ P
Sbjct: 1792 QVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP-G 1850
Query: 1715 SEPGCF-LVGGKPSSCQENSMADAWNKN-CAILINPQG-PFSQCHQVVPPQSSFASCVHG 1771
+P C+ G +C E+ + C L + G PF+ CH VPP+S F CV
Sbjct: 1851 WDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLD 1910
Query: 1772 QCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCS 1830
C GD LC++L +Y + C AG WR + C + CP S Y C PCP +C
Sbjct: 1911 VCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCP 1970
Query: 1831 S---INNPRDCPKALPCAESCECQKGHILSGTSCVPLGQ-CGCTDPAGSYHPVGERWYTE 1886
S + P C PC E C+C G +LS CVPL CGC G+YH G ++ +
Sbjct: 1971 SPAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWAD 2027
Query: 1887 NTCTRLCTCSVHN-NITCFQSTCKPNQICWAL-DGLLRCRASGVGVCQLPGESHYVSFDG 1944
TC++ C C ++ C ++C ++C L G C+ CQ G+ HYV+ DG
Sbjct: 2028 GTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDG 2087
Query: 1945 SNHSIPDACTLVLVKVCH-PAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQ 2003
C +L CH P + F ++ +E G V + IY+ +TL
Sbjct: 2088 HRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE-HRGSQAVSYTRSVTLQIYNHSLTLS 2146
Query: 2004 KG--HRVLINSKQVTLP-AISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTT 2060
++ ++ V LP + + + + + +V G+ + FDG+ + + +P
Sbjct: 2147 ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADV--VVTTTSGLSLAFDGDSFVRLRVPAA 2204
Query: 2061 YYGKVCGMCGNFNDEEEDELMMPSDEVAN---SDSEFVNSWKDKDIDPSCQSLLVDEQQI 2117
Y +CG+CGN+N + D+L + A ++ K C
Sbjct: 2205 YAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTP-------- 2256
Query: 2118 PAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLY 2177
EQQE+ G + +A P+ A C + + C C+ G
Sbjct: 2257 --EQQESFGGPDACGVI--------SATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHP 2305
Query: 2178 QALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEG 2237
LC A+ + A CQ+ G + WR FCPL+CPA+S Y C SC SC L EG
Sbjct: 2306 GGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP-EG 2364
Query: 2238 AKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSG-CTEKCVC-T 2295
+ SAC EGC+C G+VLS D CVP QCGC G PLG+ + C +C C
Sbjct: 2365 CE--SACREGCVCDAGFVLSGDTCVPVGQCGCLH-DGRYYPLGEVFYPGPECERRCECGP 2421
Query: 2296 GGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTY 2355
GG + C + G H + ++ C + +C G Y+T DG Y L G +Y
Sbjct: 2422 GGHVTCQE-GAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSY 2480
Query: 2356 VLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKM 2415
VL + P + +V +N LQ ++ TV G V L G ++ V+ + +
Sbjct: 2481 VLAQVCHPKPGDEDFSIVLEKNAAGD------LQRLLVTVAGQVVSLAQGQQVTVDGEAV 2534
Query: 2416 AVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNR 2475
A+P +RVT G+ + L T L + F G + ++S+PS + G + GLCGN++ N
Sbjct: 2535 ALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNW 2593
Query: 2476 KNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECS 2535
+D +LP+G+ ++ TFG +W P +G G G + G V C
Sbjct: 2594 SDDFVLPNGSAASSVETFGAAWRA-------------PGSSKGCGEGCGPQ-GCPV--CL 2637
Query: 2536 PEQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVL 2594
E+ A S +AC L +PQGPFA C ++P + CV DLC+ + + C+ L
Sbjct: 2638 AEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA---QKGDKAFLCRSL 2694
Query: 2595 SGH-------GVSSR----------YHISELYDTLPSILCQPGRPRGLRGPLRGRLRQ-- 2635
+ + GV+ + + + + ++ + CQ G L G L G +
Sbjct: 2695 AAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQ-GSCAALSG-LTGCTTRCF 2752
Query: 2636 -----HPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFS 2690
R L P+ DCGCT NG Y + SS LT DCS+RC+C+SS L C+
Sbjct: 2753 EGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAG 2812
Query: 2691 CRAGEVCTLGNHTQGCF 2707
C G VC + + C+
Sbjct: 2813 CPPGRVCEVKAEARNCW 2829
Score = 842 bits (2175), Expect = 0.0
Identities = 556/1782 (31%), Positives = 795/1782 (44%), Gaps = 143/1782 (8%)
Query: 1017 MSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESC--ACPASCK---SPRPSCGPLCR 1071
+S +A + + +G + + CP N+RYE C ACP SC +P G C
Sbjct: 718 LSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCV 777
Query: 1072 EGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQI 1129
EGCVC PGF+ S C+ ASSC C + PG E W C C C + +V C+
Sbjct: 778 EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 837
Query: 1130 SQ-CGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCG- 1187
Q C C ++NG GC+P TC GDPHYV+FDGR F FMG CTY+L CG
Sbjct: 838 KQSCPAGERCSVQNGLLGCYP-DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQ 896
Query: 1188 NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLK--GRRTLVGGQQVTLPAIPS 1245
N+ P FRV +NE +G + VS V V V + + + LV LP +
Sbjct: 897 NAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAA 956
Query: 1246 KG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLK 1304
G V + GR ++T+FGL V +D + ++ V S+Y+ LCGLCGN++G+ +D
Sbjct: 957 DGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLAL 1016
Query: 1305 LDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP 1364
G A + GNSWQ ++ C + + P DS + + CG L D GP
Sbjct: 1017 RGGGQAANALAFGNSWQ--EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGP 1074
Query: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
F C + C+ D C G LC ++T CQ AG V PWR CP+
Sbjct: 1075 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL 1134
Query: 1425 ACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
+CPP+S Y C+ CP +C C C E C C+ GF LSG C+P + CGC+H
Sbjct: 1135 SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVH- 1193
Query: 1485 AGSYFKVGERWYK-PGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCT 1543
G+Y G+ +Y PGC LC C+ + C+ C E C G GC A G++TC
Sbjct: 1194 QGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQ 1253
Query: 1544 ASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAV 1602
ASGDPHY TFDG FMGTC YVL + C +R F V N G G + V+ + V
Sbjct: 1254 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 1313
Query: 1603 HVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSH 1662
V F L + R KV +NG + LPV LA G++ + V++ T+FGL+V YD +
Sbjct: 1314 QVANFTLRLE-QRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVY 1372
Query: 1663 LVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWK--LPES------ 1714
V VTVP +Y Q+CGLCGNYN + DD +P+ AG++ + G +W+ +P+S
Sbjct: 1373 YVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT 1432
Query: 1715 -SEPG---CFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVH 1770
PG C P ++ + + C +L +P GP S CH++V PQ C+
Sbjct: 1433 PCPPGSEDCIPSHKCPPELEKKYQKEEF---CGLLSSPTGPLSSCHKLVDPQGPLKDCIF 1489
Query: 1771 GQCGTKGDTTALCRSLQAYASLC-AQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTC 1829
C G+ + LC ++ AY S C A G WR TFCPM CPP S Y C+ C C
Sbjct: 1490 DLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC 1549
Query: 1830 SSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTC 1889
S+++ P C CAE C+C G + +G +CVP+ QCGC Y P E+ + C
Sbjct: 1550 SALSAPPQCQDG--CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEP--EQTVLIDNC 1605
Query: 1890 TRLCTCSVHNNITCFQSTCKPNQICWALDGLLRC------------------RASGVGV- 1930
+ CTC + C + +CKP Q+C G+L C G GV
Sbjct: 1606 RQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVC 1665
Query: 1931 -------CQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMA---LPFFKISAKHEKEE 1980
C L G+ HY SFDG C VL P ++ L F ++ K++
Sbjct: 1666 LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ-NR 1724
Query: 1981 GGTEAFRLHEVYIDIYDAQVTLQKGH----RVLINSKQVTLPAISQIPGVSVKSSSIYSI 2036
G + V + +++ K RV +N LP +SV + ++
Sbjct: 1725 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKAL 1784
Query: 2037 VNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVN 2096
+ G+QV +D N +++ +P++Y+G VCG+CGN + ++ + P+ +A S +
Sbjct: 1785 LVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGG 1844
Query: 2097 SWKDKDIDP----SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQ 2152
SW+ DP C+ + EQ E P G C A+ +
Sbjct: 1845 SWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGP-GFCGPL----------ASGTGGPFTT 1893
Query: 2153 CASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECP 2212
C + + F C +C GG LC+AL ++ A CQ+ G+ WR C + CP
Sbjct: 1894 CHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCP 1953
Query: 2213 AYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVP-RSQCGCKD 2271
S Y C P C SC A C EGC C G+VLS D+CVP + CGC
Sbjct: 1954 ENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW- 2012
Query: 2272 AHGGSIPLGKS-WVSSGCTEKCVC--TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKS 2328
A+G G W C++ C C GG++ C C G C L + C +
Sbjct: 2013 ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH-GCQPVST 2071
Query: 2329 EQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFL 2388
+C +GDP Y+T DG + QG Y+L P G E V N+ ++ +
Sbjct: 2072 AECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYT 2131
Query: 2389 QEVITTVYGYKVQLQA--GLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSF 2446
+ V +Y + + L A +L V+ +A+P++ + L L G + + T L ++F
Sbjct: 2132 RSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAF 2191
Query: 2447 GGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALL 2506
G + +P+ Y + GLCGNY+++ +D+ G W+V
Sbjct: 2192 DGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQV------- 2236
Query: 2507 RFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLADPQGPFAACHQTVA 2565
+G G + S C+PEQ S AC V++ GP A CH V
Sbjct: 2237 -------GGAQGCGECVSKPC---PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVP 2286
Query: 2566 PEPFQEHCVLDLCSAQD------PREQEEL-RCQVLSGH------------GVSSRYHIS 2606
P + + C+LD C Q P + CQ + H
Sbjct: 2287 PAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYE 2346
Query: 2607 ELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSS 2666
D+ P P G R L P+ CGC +G YY LG
Sbjct: 2347 LCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEV 2406
Query: 2667 FLT-EDCSQRCTCASSRILLC-EPFSCRAGEVCTLGNHTQGC 2706
F +C +RC C + C E +C E C L + Q C
Sbjct: 2407 FYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQAC 2448
Score = 816 bits (2109), Expect = 0.0
Identities = 532/1667 (31%), Positives = 762/1667 (45%), Gaps = 123/1667 (7%)
Query: 1127 CQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPC 1186
C+ QC CQ+ G+ GC + TA C GDPHY TFDGR + MG C+Y + + C
Sbjct: 444 CEGMQCAAGQRCQVVGGKAGCVAES-TAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 502
Query: 1187 G-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRR--TLVGGQQVTLPAI 1243
+ T P F V AKNE +G VS + V V +V+L +G LV Q+ LP
Sbjct: 503 SEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 562
Query: 1244 PSKG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDH 1302
S+G + + SG ++ FGL V +D D QL +++ + + ++CGLCGNY+G+ +D
Sbjct: 563 LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 622
Query: 1303 LKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTH 1362
L DG+ A D E +SW+ D D D C+ N P+C G CG L
Sbjct: 623 LTPDGALAPDAVEFASSWKLD-DGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 681
Query: 1363 GPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFC 1422
GPF C + F + C+ D+C G + LC +S C + G +V WR P C
Sbjct: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
Query: 1423 PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR-CVEACECNPGFVLSGLECIPRSQCGC 1481
P++CP NS+Y LC CP +C+ + CS R CVE C C PGFV SG C+P S CGC
Sbjct: 742 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801
Query: 1482 LHPAGSYFKVGERWYKPGCKELCVCE-SNNRIRCQPWR-CRAQEFCGQQDGIYGCHAQGA 1539
E W C+ C C + +++ C+ + C A E C Q+G+ GC+
Sbjct: 802 TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 861
Query: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYI 1599
TC SGDPHY++FDG FMGTCTY+L C + F V NE+RG VSY
Sbjct: 862 GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGS-QTVSYT 920
Query: 1600 KAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVR 1657
+AV V + +++ R +V+++ LP A G+V + ++ T+FGL V
Sbjct: 921 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 980
Query: 1658 YDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEP 1717
YD + V VPSSY LCGLCGN+N + DD A +++ G +W+ E + P
Sbjct: 981 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ--EETRP 1038
Query: 1718 GCFLVGGKPSSCQENSMADA---WNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
GC +P C + A +KN C IL +P+GPF +CH + PQ + CV+ +C
Sbjct: 1039 GCGAT--EPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRC 1096
Query: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
G + LC +L YA+ C AG WR+ CP+ CPP S Y CS CP +C +
Sbjct: 1097 LLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDL 1156
Query: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
P C C E C C +G LSG SC+PL CGC G+YHP G+ +Y C L
Sbjct: 1157 PVPGGC--GSECHEGCVCDEGFALSGESCLPLASCGCVH-QGTYHPPGQTFYPGPGCDSL 1213
Query: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
C C ++C S+C P++ C G L C A G CQ G+ HY +FDG
Sbjct: 1214 CHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGT 1273
Query: 1953 CTLVLVKVCHPAMALPFFKISAKHEK-EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLIN 2011
C VL + C L F + ++ G R+ V + + ++ Q+ +V +N
Sbjct: 1274 CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE-QRQWKVTVN 1332
Query: 2012 SKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGN 2071
+ LP + + ++ G++V +D + + + +P YY ++CG+CGN
Sbjct: 1333 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGN 1392
Query: 2072 FNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRA 2131
+N + +D+ P+ A + +EF NSW++ D C L P + PS C
Sbjct: 1393 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC---LPPTPCPPGSEDCIPSHKC-P 1448
Query: 2132 ADLRRAREKCE--AALRAPV--WAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAF 2187
+L + +K E L +P + C +D L DC LC GG LC + A+
Sbjct: 1449 PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAY 1508
Query: 2188 GATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDG--RCEGAKVPSACA 2245
+ CQ+ G WR +FCP+ECP S Y C +CS C L +C+ CA
Sbjct: 1509 VSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQ-----DGCA 1563
Query: 2246 EGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVC-TGGAIQCGDF 2304
EGC C G++ + CVP QCGC +G ++ + C ++C C G + C +
Sbjct: 1564 EGCQCDSGFLYNGQACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH 1622
Query: 2305 RCPSGSHCQ--------LTSD----------------NSNSNCVSDKSEQCSVYGDPRYL 2340
C G CQ +T D C+ + C ++GDP Y
Sbjct: 1623 SCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYH 1682
Query: 2341 TFDGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGY 2398
+FDG + QG YVL T V +G+ P V +N+ + +++ V G
Sbjct: 1683 SFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGT 1742
Query: 2399 KVQLQ----AGLELVVNNQKMAVPYR-PNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAV 2453
+ + + + VN A+P + + V + LV DF L VS+
Sbjct: 1743 NISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVD 1802
Query: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513
++LPS Y G V GLCGN D+N ND + P+G L ++ +G SW D L
Sbjct: 1803 VTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL-------- 1854
Query: 2514 AEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLAD-PQGPFAACHQTVAPEPFQE 2571
+E +G+ C ++L C LA GPF CH V PE F +
Sbjct: 1855 CWDECRGS---------CPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFK 1905
Query: 2572 HCVLDLCSAQDPRE-------------------QEELRCQVLSGHGVSSRYHISELYDTL 2612
CVLD+C R+ E+ R QV H
Sbjct: 1906 GCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPC 1965
Query: 2613 PSILCQPG---RPRGLRGPLRGRLRQHPRLCLQWHPEPPLAD-CGCTSNGIYYQLGSSFL 2668
P+ P P GP + L PL + CGC +NG Y++ GS F
Sbjct: 1966 PASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFW 2025
Query: 2669 TE-DCSQRCTCA-SSRILLCEPFSCRAGEVCTL---GNHTQGCFPES 2710
+ CSQ C C L+C P SC GEVC L G H GC P S
Sbjct: 2026 ADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH--GCQPVS 2070
Score = 753 bits (1944), Expect = 0.0
Identities = 484/1504 (32%), Positives = 698/1504 (46%), Gaps = 122/1504 (8%)
Query: 1044 CPPNARYESCA--CPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
CPPN+ YE CA C C S P C C EGC C+ GFL++ C+ C C++N
Sbjct: 1532 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 1591
Query: 1100 DYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGC---HPYAGT--- 1153
YYEP NC + C C G + CQ C VCQ G C P G
Sbjct: 1592 VYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCR 1651
Query: 1154 -------------------ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C-GNSTDP 1192
ATC ++GDPHY +FDGR F F G C Y+LA C G ST
Sbjct: 1652 PQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQG 1711
Query: 1193 F--FRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR----RTLVGGQQVTLPAIPSK 1246
F VT KN+ +G VS + V V + +++ K R V G LP +
Sbjct: 1712 LTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVAD 1771
Query: 1247 GVFLGASGRFVELQT-EFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKL 1305
G A G L +FGL+V +D + ++ VT+ S+Y G +CGLCGN D N +ND +
Sbjct: 1772 GRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 1831
Query: 1306 DGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVD-THGP 1364
+G+ A G SW+ D C + P+C GPGFCG L T GP
Sbjct: 1832 NGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGP 1890
Query: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
F TC HV SFF C+LD+C G + +LC +++ CQ AG ++ WR C +
Sbjct: 1891 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 1950
Query: 1425 ACPPNSKYSLCAKPCPDTCHSGF---SGMFCSDRCVEACECNPGFVLSGLECIPRSQ-CG 1480
CP NS Y +C PCP +C S + C CVE C+C+ GFVLS C+P + CG
Sbjct: 1951 TCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG 2010
Query: 1481 CLHPAGSYFKVGERWYKPG-CKELCVC-ESNNRIRCQPWRCRAQEFCGQ-QDGIYGCHAQ 1537
C G+Y + G ++ G C + C C + C P C E CG G +GC
Sbjct: 2011 CW-ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPV 2069
Query: 1538 GAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSY-FVVSATNENRGGILEV 1596
A C A GDPHY+T DG F GTC Y+L+ PC + F V+ NE+RG V
Sbjct: 2070 STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAV 2128
Query: 1597 SYIKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654
SY ++V + +++ S++L K+ ++G VALP L + LS V++ T GL
Sbjct: 2129 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVVTTTSGL 2187
Query: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714
+ +DG V + VP++Y LCGLCGNYN + DD K AG Q+G A E
Sbjct: 2188 SLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--WQVGGAQGCGEC 2245
Query: 1715 SEPGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
C PS C + C ++ GP + CH +VPP F C+ C
Sbjct: 2246 VSKPC------PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 2299
Query: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
+G LC ++ Y + C AG Q WR FCP++CP S Y C CP +C S+
Sbjct: 2300 QVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSL 2359
Query: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
+ P C A C E C C G +LSG +CVP+GQCGC G Y+P+GE +Y C R
Sbjct: 2360 SAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERR 2416
Query: 1893 CTCSVHNNITCFQ-STCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPD 1951
C C ++TC + + C P++ C DG+ C A+G G C G HY++ DG + +
Sbjct: 2417 CECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHG 2476
Query: 1952 ACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLIN 2011
+C+ VL +VCHP F I EK G L + + + V+L +G +V ++
Sbjct: 2477 SCSYVLAQVCHPKPGDEDFSIVL--EKNAAGD----LQRLLVTVAGQVVSLAQGQQVTVD 2530
Query: 2012 SKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGN 2071
+ V LP + V V + ++ G+++ FDG+ L + IP+ + G++CG+CGN
Sbjct: 2531 GEAVALPVA--VGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGN 2588
Query: 2072 FNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQS--------LLVDEQQIPAEQQE 2123
FN D+ ++P+ A+S F +W+ C + + E+ P E E
Sbjct: 2589 FNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNE 2648
Query: 2124 NPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQA 2183
LR + +A C + + + + C LC G LC++
Sbjct: 2649 ------ACGQLRNPQGP---------FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRS 2693
Query: 2184 LQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSA 2243
L A+ A CQ+ G+ WR SFCPL CPA+S Y+ C +C SC L G +
Sbjct: 2694 LAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL---TGCTTR 2750
Query: 2244 CAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGA-IQCG 2302
C EGC C ++LS+ C+P CGC +G +P+ S ++S C+E+C C+ + + C
Sbjct: 2751 CFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSSSGLTCQ 2809
Query: 2303 DFRCPSGSHCQLTSDNSN-----SNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVL 2357
CP G C++ ++ N CV + + R T Y L R L
Sbjct: 2810 AAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP-GL 2868
Query: 2358 IKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMA- 2416
T+ E + G+ + + IF Q+ + T+ K GL + + +K+A
Sbjct: 2869 QNTIPWYRVVAEVQICHGKTEA-VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLAS 2927
Query: 2417 --VPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKN 2474
V P+ L V + V G + + + + G + G CGN+D +
Sbjct: 2928 VSVSRTPDGSLLVR---------QKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGD 2978
Query: 2475 RKND 2478
+ ND
Sbjct: 2979 QTND 2982
Score = 646 bits (1667), Expect = 0.0
Identities = 392/1088 (36%), Positives = 549/1088 (50%), Gaps = 63/1088 (5%)
Query: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
CP N+ YE C CPASC SP P P C EGC C+ GF+ S + C+ ++ C C
Sbjct: 1952 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 2011
Query: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
+ N Y+E G+E W C++ CRC PG + C + CG VC L +GQ+GC P +
Sbjct: 2012 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 2070
Query: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
TA C +GDPHYVT DG F F G C Y+L+ PC F VT NE +G + VS
Sbjct: 2071 TAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 2130
Query: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
V + + ++TL R+ V G V LP + SG V + T GL +
Sbjct: 2131 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLA 2190
Query: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
+DGD + + V + Y+ LCGLCGNY+ + +D + G PAG WQ Q
Sbjct: 2191 FDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 2240
Query: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
C + PS C Q S GP CG + T GP C V A +F C+LD C
Sbjct: 2241 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 2300
Query: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
QG LC ++T CQ AG + WR P FCP+ CP +S Y LC CP +C S
Sbjct: 2301 VQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLS 2360
Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
+ C C E C C+ GFVLSG C+P QCGCLH G Y+ +GE +Y P C+ C C
Sbjct: 2361 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERRCEC 2419
Query: 1507 ESNNRIRCQPW-RCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCT 1565
+ CQ C E C +DG+ CHA G C A+G HY+T DG ++ G+C+
Sbjct: 2420 GPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCS 2479
Query: 1566 YVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
YVL + C + D F + +N G L+ + VTV +SL +G +V ++G
Sbjct: 2480 YVLAQVCHPKPGDEDFSI-VLEKNAAGDLQ-----RLLVTVAGQVVSLAQGQQVTVDGEA 2533
Query: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
VALPV A GRV + ++L T GL++ +DG + +++PS + G+LCGLCGN+N
Sbjct: 2534 VALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNG 2591
Query: 1686 NSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSC----QENSMADAWNKN 1741
N DD + P+ A GAAW+ P SS+ GC G P C E + N+
Sbjct: 2592 NWSDDFVLPNGSAASSVETFGAAWRAPGSSK-GCG-EGCGPQGCPVCLAEETAPYESNEA 2649
Query: 1742 CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-P 1800
C L NPQGPF+ C V+ P F CV+ C KGD LCRSL AY + C AG A
Sbjct: 2650 CGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVK 2709
Query: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860
WR +FCP+ CP S YS C+ C +C++++ C C E CEC +LS
Sbjct: 2710 PWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGC--TTRCFEGCECDDRFLLSQGV 2767
Query: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920
C+P+ CGCT G Y PV T + C+ C+CS + +TC + C P ++C
Sbjct: 2768 CIPVQDCGCTH-NGRYLPVNSSLLTSD-CSERCSCSSSSGLTCQAAGCPPGRVCEVKAEA 2825
Query: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAM--ALPFFKISAKHEK 1978
C A+ G+C L ++ +FDG+ + L C P + +P++++ A+ +
Sbjct: 2826 RNCWATR-GLCVLSVGANLTTFDGARGATTSPGVYELSSRC-PGLQNTIPWYRVVAEVQI 2883
Query: 1979 EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYS-IV 2037
G TEA + +V+I D VTL V +N +V LPA ++ VSV + S +V
Sbjct: 2884 CHGKTEA--VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPA-EKLASVSVSRTPDGSLLV 2940
Query: 2038 NIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
K GVQV N + + + + GK+CG CGNF+ ++ ++ ++ A +
Sbjct: 2941 RQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPA------MEK 2994
Query: 2098 WKDKDIDP 2105
W+ +D P
Sbjct: 2995 WRAQDFSP 3002
Score = 597 bits (1539), Expect = e-170
Identities = 392/1267 (30%), Positives = 580/1267 (45%), Gaps = 93/1267 (7%)
Query: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCW 1573
C+ +C A + C G GC A+ A C A GDPHY TFDG + MGTC+Y + C
Sbjct: 444 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 503
Query: 1574 SRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCK--VMLNGHRVALPVW 1631
F V A NE+RG VSY+ V V + S+SL RG V+++ R LPV
Sbjct: 504 EDDTLPAFSVEAKNEHRGS-RRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 562
Query: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDN 1691
L++GR+ + S ++ FGL V YD + +++P+ + Q+CGLCGNYN + DD
Sbjct: 563 LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 622
Query: 1692 LRPDRKLAGDSMQLGAAWKLPESS---EPGCFLVGGKPSSCQENSMADAWNKNCAILINP 1748
L PD LA D+++ ++WKL + E GC P+ + ++ C +L
Sbjct: 623 LTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTKL 680
Query: 1749 QGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPA-WRNRTF 1807
GPF+ CH + P+ CV+ C G+ +LCR L AYA C + G + WR+
Sbjct: 681 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 740
Query: 1808 CPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC 1867
CP+ CP S Y C CP +C+ P +C PC E C C G + SG +CVP C
Sbjct: 741 CPLSCPANSRYELCGPACPTSCNGAAAPSNC-SGRPCVEGCVCLPGFVASGGACVPASSC 799
Query: 1868 GCTDPAGSYHPVGERWYTENTCTRLCTCS-VHNNITCF-QSTCKPNQICWALDGLLRCRA 1925
GCT P E W E C R CTC+ + +TC + +C + C +GLL C
Sbjct: 800 GCTFQGLQLAPGQEVWADE-LCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 858
Query: 1926 SGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEA 1985
G CQ G+ HYVSFDG CT +LV C ALP F++ ++E T +
Sbjct: 859 DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS 918
Query: 1986 FRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGV 2043
+ V ++ +V +++ + +VL++ LP + V V ++V G+
Sbjct: 919 YT-RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGL 977
Query: 2044 QVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDI 2103
V +D N + ++P++Y +CG+CGNFN + D+L + A + F NSW++ +
Sbjct: 978 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQE-ET 1036
Query: 2104 DPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCE--AALRAPVWAQCASRIDLTP 2161
P C + E + P + A +++ +C A + P + +C S++D
Sbjct: 1037 RPGCGA---------TEPGDCPKLDSLVAQQLQSKNECGILADPKGP-FRECHSKLDPQG 1086
Query: 2162 FLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCL 2221
+ DC C G LC AL + A CQ+ G WR+ CPL CP +S Y C
Sbjct: 1087 AVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACS 1146
Query: 2222 PSCSPSCWDLD--GRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSI-P 2278
C SC DL G C S C EGC+C G+ LS + C+P + CGC H G+ P
Sbjct: 1147 YGCPLSCGDLPVPGGCG-----SECHEGCVCDEGFALSGESCLPLASCGC--VHQGTYHP 1199
Query: 2279 LGKSWVSS-GCTEKCVCT-GGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGD 2336
G+++ GC C C GG + C C CQ + CV+ S C GD
Sbjct: 1200 PGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQ--PSGGSLGCVAVGSSTCQASGD 1257
Query: 2337 PRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITT-V 2395
P Y TFDG + G YVL +T P G+ V N + + + VIT V
Sbjct: 1258 PHYTTFDGRRFDFMGTCVYVLAQTCGTRP-GLHRFAVLQEN-VAWGNGRVSVTRVITVQV 1315
Query: 2396 YGYKVQL-QAGLELVVNNQKMAVPY-RPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAV 2453
+ ++L Q ++ VN M +P N +R + G + + TDF L V++
Sbjct: 1316 ANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVR 1375
Query: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513
+++P Y + GLCGNY+ + K+D P+G+ N N FGNSWE D+ P P
Sbjct: 1376 VTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCP 1435
Query: 2514 AEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVLADPQGPFAACHQTVAPEPFQEH 2572
G + +C PE + + C +L+ P GP ++CH+ V P+ +
Sbjct: 1436 P---------GSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 1486
Query: 2573 CVLDLCSAQDPRE-------QEELRCQVLSGHGVSSRY------------HISELYDTLP 2613
C+ DLC CQ GH R H DT
Sbjct: 1487 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCS 1546
Query: 2614 ---SIL-----CQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGS 2665
S L CQ G G + + + C+ P+ CGC NG+YY+
Sbjct: 1547 LGCSALSAPPQCQDGCAEGCQ--CDSGFLYNGQACV------PIQQCGCYHNGVYYEPEQ 1598
Query: 2666 SFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQCRE 2725
+ L ++C Q+CTC + + ++C+ SC+ G+VC C + PC C+ C+E
Sbjct: 1599 TVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKE 1658
Query: 2726 QGATFTC 2732
QG C
Sbjct: 1659 QGGQGVC 1665
Score = 376 bits (965), Expect = e-103
Identities = 221/659 (33%), Positives = 316/659 (47%), Gaps = 25/659 (3%)
Query: 1043 RCPPNARYESC--ACPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
+CP ++ YE C +CP SC S C CREGCVC+ GF+ S + C+ C C ++
Sbjct: 2338 QCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 2397
Query: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQI-SQCGTHTVCQLKNGQYGCHPYAGTATC 1156
YY G ++ P C C C PG V CQ + CG H C+L++G CH G C
Sbjct: 2398 GRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHA-TGCGRC 2456
Query: 1157 LVYGDPHYVTFDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQEGVSCLSKVY 1215
L G HY+T DGR + G C+Y+LAQ C D F + + G L ++
Sbjct: 2457 LANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLL 2511
Query: 1216 VTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQL 1275
VT+ V+L +G++ V G+ V LP + V + A GR + LQT GLR+ +DGD L
Sbjct: 2512 VTVAGQVVSLAQGQQVTVDGEAVALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGDAHL 2570
Query: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQV 1335
+++ S + G+LCGLCGN++GN +D + +GS A E G +W+ +
Sbjct: 2571 LMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGP 2630
Query: 1336 VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLL 1395
P C + + CG+L + GPF TC + + +F C+ D+C +G + L
Sbjct: 2631 QGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFL 2690
Query: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH--SGFSGMFCS 1453
C ++ T CQ AG AVKPWR FCP+ CP +S YS+C + C +C SG +G C+
Sbjct: 2691 CRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG--CT 2748
Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIR 1513
RC E CEC+ F+LS CIP CGC H G Y V C E C C S++ +
Sbjct: 2749 TRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSSSGLT 2807
Query: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPC- 1572
CQ C C + C A C S + TFDGA Y L+ C
Sbjct: 2808 CQAAGCPPGRVCEVKAEARNCWAT-RGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP 2866
Query: 1573 -WSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVW 1631
+ Y VV+ G + + VH+ D ++L V +NG RV LP
Sbjct: 2867 GLQNTIPWYRVVAEVQICHG---KTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAE 2923
Query: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
R +L+ G+QV + V V V + + G+LCG CGN++ + +D
Sbjct: 2924 KLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 2982
Score = 323 bits (829), Expect = 1e-87
Identities = 235/847 (27%), Positives = 357/847 (42%), Gaps = 87/847 (10%)
Query: 1902 TCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVC 1961
+C C Q C + G C A VC+ G+ HY +FDG + + C+ +V++C
Sbjct: 443 SCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 502
Query: 1962 HPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPA 2019
LP F + AK+E G + V + Y V+L +G VL+++++ LP
Sbjct: 503 SEDDTLPAFSVEAKNE-HRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 561
Query: 2020 ISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDE 2079
+ V S ++V + G+ V +D + L + +P + +VCG+CGN+N + D+
Sbjct: 562 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 621
Query: 2080 LMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPA---EQQENPSGNCRAADLRR 2136
+ P +A EF +SWK D D C+ + PA Q ++ G+ L +
Sbjct: 622 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTK 679
Query: 2137 AREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGL 2196
L P +A C +D PFL C LC GG +LC+ L A+ C G+
Sbjct: 680 --------LDGP-FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGI 730
Query: 2197 KPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPS-----ACAEGCICQ 2251
WR+ + CPL CPA S Y C P+C S C GA PS C EGC+C
Sbjct: 731 SVGDWRSPANCPLSCPANSRYELCGPACPTS-------CNGAAAPSNCSGRPCVEGCVCL 783
Query: 2252 PGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGA--IQCGDFR-CPS 2308
PG+V S CVP S CGC P + W C +C C G + C D + CP+
Sbjct: 784 PGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPA 843
Query: 2309 GSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVD---VLP 2365
G C + N C D+ C GDP Y++FDG + G TY+L+ + LP
Sbjct: 844 GERCSV--QNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALP 901
Query: 2366 EGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE 2423
+LVE ++ S + + V G KV ++ +++V++ +P++ +
Sbjct: 902 --AFRVLVENEHRGSQTVS--YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAAD 957
Query: 2424 -HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLP 2482
++V G+ + TDF L V++ +PS Y + GLCGN++ + +D+ L
Sbjct: 958 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
Query: 2483 SGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASN 2542
G N FGNSW+ +T A E G +L Q+
Sbjct: 1018 GGGQAANALAFGNSWQEETRP-------GCGATEPGDCPKLDSLVAQQL----------Q 1060
Query: 2543 STQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSR 2602
S C +LADP+GPF CH + P+ CV D C P + L C L+ + + +
Sbjct: 1061 SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL--PGQSGPL-CDALATYAAACQ 1117
Query: 2603 YHISELY----DTLPSILCQPGR------------------PRGLRGPLRGRLRQHPRLC 2640
+ ++ + L + C P P G
Sbjct: 1118 AAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFA 1177
Query: 2641 LQWHPEPPLADCGCTSNGIYYQLGSSFLT-EDCSQRCTCASSRILLCEPFSCRAGEVCTL 2699
L PLA CGC G Y+ G +F C C C ++ CE SC E C
Sbjct: 1178 LSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQP 1237
Query: 2700 GNHTQGC 2706
+ GC
Sbjct: 1238 SGGSLGC 1244
>gi|239757282 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1403
Score = 686 bits (1769), Expect = 0.0
Identities = 448/1396 (32%), Positives = 653/1396 (46%), Gaps = 104/1396 (7%)
Query: 1127 CQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP- 1185
C C C+ + GQ C P ATC ++GDPHY +FDGR F F G C Y+LA
Sbjct: 47 CHGVTCRPQETCKEQGGQGVCLPNY-EATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 105
Query: 1186 -CGNSTDPF--FRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR--RTLVGGQQVTL 1240
G ST F VT KNE +G VS + V V + +++ K + V G L
Sbjct: 106 CLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165
Query: 1241 PAIPSKGVFLGASGRFVELQT-EFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSD 1299
P + G A G L +FGL+V +D + ++ VT+ S+Y G +CGLCGN D N +
Sbjct: 166 PVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPN 225
Query: 1300 NDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLV 1359
ND + +G+ A G SW+ D C + P+C GPGFCG L
Sbjct: 226 NDQVFPNGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLA 284
Query: 1360 D-THGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWRE 1418
T GPF TC HV SFF C+LD+C G +LC +++ CQ AG ++ WR
Sbjct: 285 PGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRA 344
Query: 1419 PHFCPMACPPNSKYSLCAKPCPDTCHSG---FSGMFCSDRCVEACECNPGFVLSGLECIP 1475
C + CP NS Y +C PCP +C S + C CVE C+C+ GFVLS C+P
Sbjct: 345 QVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVP 404
Query: 1476 -RSQCGCLHPAGSYFKVGERWYKPG-CKELCVC-ESNNRIRCQPWRCRAQEFCG-QQDGI 1531
+ CGC G+Y + G ++ G C + C C + C P C E CG G
Sbjct: 405 LNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQ 463
Query: 1532 YGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDS-YFVVSATNENR 1590
+GC A C A GDPHY+T DG F GTC Y+L+ PC + F V+ NE+R
Sbjct: 464 HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHR 523
Query: 1591 GGILEVSYIKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLL 1648
G VSY ++V + +++ S++L K+ ++G VALP L + LS V++
Sbjct: 524 GS-QAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVV 581
Query: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708
T GL + +DG V + VP++Y LCGLCGNYN + DD K AG Q+G A
Sbjct: 582 TTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--WQVGGA 639
Query: 1709 WKLPESSEPGCFLVGGKPSSC-QENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFAS 1767
E C PS C E + C ++ GP + CH +VPP F
Sbjct: 640 QGCGECVSKPC------PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQG 693
Query: 1768 CVHGQCGTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCP 1826
C+ C +G LC ++ Y + C AG Q WR FCP++CP S Y C CP
Sbjct: 694 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCP 753
Query: 1827 DTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTE 1886
+C S++ P C A C E C C G +LSG +CVP+GQCGC G Y+P+GE +Y
Sbjct: 754 VSCPSLSAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPG 810
Query: 1887 NTCTRLCTCSVHNNITCFQ-STCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGS 1945
C R C C ++TC + + C P++ C DG+ C A+G G C G HY++ DG
Sbjct: 811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 870
Query: 1946 NHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKG 2005
+ + +C+ VL +VCHP F I EK G L + + + V+L +G
Sbjct: 871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVL--EKNAAGD----LQRLLVTVAGQVVSLAQG 924
Query: 2006 HRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKV 2065
+V ++ + V LP + V V + ++ G+++ FDG+ L + IP+ + G++
Sbjct: 925 QQVTVDGEAVALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRL 982
Query: 2066 CGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQS--------LLVDEQQI 2117
CG+CGNFN D+ ++P+ A+S F +W+ C + + E+
Sbjct: 983 CGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETA 1042
Query: 2118 PAEQQE------NPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLC 2171
P E E NP G +A C + + + + C LC
Sbjct: 1043 PYESNEACGQLRNPQG---------------------PFATCQAVLSPSEYFRQCVYDLC 1081
Query: 2172 EFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDL 2231
G LC++L A+ A CQ+ G+ WR SFCPL CPA+S Y+ C +C SC L
Sbjct: 1082 AQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAAL 1141
Query: 2232 DGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEK 2291
G + C EGC C ++LS+ C+P CGC +G +P+ S ++S C+E+
Sbjct: 1142 SGL---TGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSER 1197
Query: 2292 CVCTGGA-IQCGDFRCPSGSHCQLTSDNSN-----SNCVSDKSEQCSVYGDPRYLTFDGF 2345
C C+ + + C CP G C++ ++ N CV + + R T
Sbjct: 1198 CSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPG 1257
Query: 2346 SYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAG 2405
Y L R L T+ E + G+ + + IF Q+ + T+ K G
Sbjct: 1258 VYELSSRCP-GLQNTIPWYRVVAEVQICHGKTEA-VGQVHIFFQDGMVTLTPNKGVWVNG 1315
Query: 2406 LELVVNNQKMA---VPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEG 2462
L + + +K+A V P+ L V + V G + + + + G
Sbjct: 1316 LRVDLPAEKLASVSVSRTPDGSLLVR---------QKAGVQVWLGANGKVAVIVSNDHAG 1366
Query: 2463 LVSGLCGNYDKNRKND 2478
+ G CGN+D ++ ND
Sbjct: 1367 KLCGACGNFDGDQTND 1382
Score = 647 bits (1669), Expect = 0.0
Identities = 392/1088 (36%), Positives = 550/1088 (50%), Gaps = 63/1088 (5%)
Query: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
CP N+ YE C CPASC SP P P C EGC C+ GF+ S + C+ ++ C C
Sbjct: 352 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 411
Query: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
+ N Y+E G+E W C++ CRC PG + C + CG VC L +GQ+GC P +
Sbjct: 412 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 470
Query: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
TA C +GDPHYVT DG F F G C Y+L+ PC F VT NE +G + VS
Sbjct: 471 TAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 530
Query: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
V + + ++TL R+ V G V LP + SG V + T GL +
Sbjct: 531 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLA 590
Query: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
+DGD + + V + Y+ LCGLCGNY+ + +D + G PAG WQ Q
Sbjct: 591 FDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 640
Query: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
C + PS C Q S GP CG + T GP C V A +F C+LD C
Sbjct: 641 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 700
Query: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
QG LC ++T CQ AG + WR P FCP+ CP +S Y LC CP +C S
Sbjct: 701 VQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLS 760
Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
+ C C E C C+ GFVLSG C+P QCGCLH G Y+ +GE +Y P C+ C C
Sbjct: 761 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERRCEC 819
Query: 1507 ESNNRIRCQPW-RCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCT 1565
+ CQ C E C +DG+ CHA G C A+G HY+T DG ++ G+C+
Sbjct: 820 GPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCS 879
Query: 1566 YVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
YVL + C + D F + +N G L+ + VTV +SL +G +V ++G
Sbjct: 880 YVLAQVCHPKPGDEDFSI-VLEKNAAGDLQ-----RLLVTVAGQVVSLAQGQQVTVDGEA 933
Query: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
VALPV A GRV + ++L T GL++ +DG + +++PS + G+LCGLCGN+N
Sbjct: 934 VALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNG 991
Query: 1686 NSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSC----QENSMADAWNKN 1741
N DD + P+ A GAAW++P SS+ GC G P C E + N+
Sbjct: 992 NWSDDFVLPNGSAASSVETFGAAWRVPGSSK-GCG-EGCGPQGCPVCLAEETAPYESNEA 1049
Query: 1742 CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-P 1800
C L NPQGPF+ C V+ P F CV+ C KGD LCRSL AY + C AG A
Sbjct: 1050 CGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVK 1109
Query: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860
WR +FCP+ CP S YS C+ C +C++++ C C E CEC +LS
Sbjct: 1110 PWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGC--TTRCFEGCECDDRFLLSQGV 1167
Query: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920
C+P+ CGCT G Y PV T + C+ C+CS + +TC + C P ++C
Sbjct: 1168 CIPVQDCGCTH-NGRYLPVNSSLLTSD-CSERCSCSSSSGLTCQAAGCPPGRVCEVKAEA 1225
Query: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAM--ALPFFKISAKHEK 1978
C A+ G+C L ++ +FDG+ + L C P + +P++++ A+ +
Sbjct: 1226 RNCWATR-GLCVLSVGANLTTFDGARGATTSPGVYELSSRC-PGLQNTIPWYRVVAEVQI 1283
Query: 1979 EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYS-IV 2037
G TEA + +V+I D VTL V +N +V LPA ++ VSV + S +V
Sbjct: 1284 CHGKTEA--VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPA-EKLASVSVSRTPDGSLLV 1340
Query: 2038 NIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
K GVQV N + + + + GK+CG CGNF+ ++ ++ ++ A +
Sbjct: 1341 RQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPA------MEK 1394
Query: 2098 WKDKDIDP 2105
W+ +D P
Sbjct: 1395 WRAQDFSP 1402
Score = 561 bits (1446), Expect = e-159
Identities = 391/1243 (31%), Positives = 573/1243 (46%), Gaps = 109/1243 (8%)
Query: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVL-TRPC 1572
C CR QE C +Q G C ATC GDPHY +FDG F GTC YVL T C
Sbjct: 47 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 106
Query: 1573 WSRSQDSY--FVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRG--CKVMLNGHRVAL 1628
S F V+ NENRG VSY++ V V +IS+ + KV +NG AL
Sbjct: 107 LGVSTQGLTPFTVTTKNENRGNPA-VSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165
Query: 1629 PVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSL 1688
PV +A GR+++ ++ LL +FGLQV YD + V+VT+PSSY G +CGLCGN + N
Sbjct: 166 PVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPN 225
Query: 1689 DDNLRPDRKLAGDSMQLGAAWKLPESSEPGCF-LVGGKPSSCQENSMADAWNKNCAILIN 1747
+D + P+ LA G +W+ P +P C+ G +C E+ + +
Sbjct: 226 NDQVFPNGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLA 284
Query: 1748 PQ--GPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRN 1804
P GPF+ CH VPP+S F CV C GD LC++L +Y + C AG WR
Sbjct: 285 PGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRA 344
Query: 1805 RTFCPMRCPPGSSYSPCSSPCPDTCSS---INNPRDCPKALPCAESCECQKGHILSGTSC 1861
+ C + CP S Y C PCP +C S + P C PC E C+C G +LS C
Sbjct: 345 QVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG--PCVEGCQCDAGFVLSADRC 402
Query: 1862 VPLGQ-CGCTDPAGSYHPVGERWYTENTCTRLCTCSVHN-NITCFQSTCKPNQICWAL-D 1918
VPL CGC G+YH G ++ + TC++ C C ++ C ++C ++C L
Sbjct: 403 VPLNNGCGCW-ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPS 461
Query: 1919 GLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCH-PAMALPFFKISAKHE 1977
G C+ CQ G+ HYV+ DG C +L CH P + F ++ +E
Sbjct: 462 GQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE 521
Query: 1978 KEEGGTEAFRLHEVYIDIYDAQVTLQKG--HRVLINSKQVTLP-AISQIPGVSVKSSSIY 2034
G V + IY+ +TL ++ ++ V LP + + + + +
Sbjct: 522 -HRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADV- 579
Query: 2035 SIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVAN---SD 2091
+V G+ + FDG+ + + +P Y +CG+CGN+N + D+L + A
Sbjct: 580 -VVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGG 638
Query: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWA 2151
++ K C EQQE+ G + +A P+ A
Sbjct: 639 AQGCGECVSKPCPSPCTP----------EQQESFGGPDACGVI--------SATDGPL-A 679
Query: 2152 QCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLEC 2211
C + + C C+ G LC A+ + A CQ+ G + WR FCPL+C
Sbjct: 680 PCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQC 739
Query: 2212 PAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKD 2271
PA+S Y C SC SC L EG + SAC EGC+C G+VLS D CVP QCGC
Sbjct: 740 PAHSHYELCGDSCPVSCPSLSAP-EGCE--SACREGCVCDAGFVLSGDTCVPVGQCGCLH 796
Query: 2272 AHGGSIPLGKSWVSSG-CTEKCVC-TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSE 2329
G PLG+ + C +C C GG + C + G H + ++ C +
Sbjct: 797 -DGRYYPLGEVFYPGPECERRCECGPGGHVTCQE-GAACGPHEECRLEDGVQACHATGCG 854
Query: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQ 2389
+C G Y+T DG Y L G +YVL + P + +V +N LQ
Sbjct: 855 RCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD------LQ 908
Query: 2390 EVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGR 2449
++ TV G V L G ++ V+ + +A+P +RVT G+ + L T L + F G
Sbjct: 909 RLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGD 967
Query: 2450 KNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFP 2509
+ ++S+PS + G + GLCGN++ N +D +LP+G+ ++ TFG +W V
Sbjct: 968 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRV---------- 1017
Query: 2510 RAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLADPQGPFAACHQTVAPEP 2568
P +G G G + G V C E+ A S +AC L +PQGPFA C ++P
Sbjct: 1018 ---PGSSKGCGEGCGPQ-GCPV--CLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 1071
Query: 2569 FQEHCVLDLCSAQDPREQEELRCQVLSGH-------GVSSR----------YHISELYDT 2611
+ CV DLC+ + + C+ L+ + GV+ + + + + +
Sbjct: 1072 YFRQCVYDLCA---QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYS 1128
Query: 2612 LPSILCQPGRPRGLRGPLRGRLRQ-------HPRLCLQWHPEPPLADCGCTSNGIYYQLG 2664
+ + CQ G L G L G + R L P+ DCGCT NG Y +
Sbjct: 1129 ICTRTCQ-GSCAALSG-LTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVN 1186
Query: 2665 SSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCF 2707
SS LT DCS+RC+C+SS L C+ C G VC + + C+
Sbjct: 1187 SSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCW 1229
Score = 376 bits (965), Expect = e-103
Identities = 221/659 (33%), Positives = 316/659 (47%), Gaps = 25/659 (3%)
Query: 1043 RCPPNARYESC--ACPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
+CP ++ YE C +CP SC S C CREGCVC+ GF+ S + C+ C C ++
Sbjct: 738 QCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 797
Query: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQI-SQCGTHTVCQLKNGQYGCHPYAGTATC 1156
YY G ++ P C C C PG V CQ + CG H C+L++G CH G C
Sbjct: 798 GRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHA-TGCGRC 856
Query: 1157 LVYGDPHYVTFDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQEGVSCLSKVY 1215
L G HY+T DGR + G C+Y+LAQ C D F + + G L ++
Sbjct: 857 LANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLL 911
Query: 1216 VTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQL 1275
VT+ V+L +G++ V G+ V LP + V + A GR + LQT GLR+ +DGD L
Sbjct: 912 VTVAGQVVSLAQGQQVTVDGEAVALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGDAHL 970
Query: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQV 1335
+++ S + G+LCGLCGN++GN +D + +GS A E G +W+ +
Sbjct: 971 LMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGP 1030
Query: 1336 VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLL 1395
P C + + CG+L + GPF TC + + +F C+ D+C +G + L
Sbjct: 1031 QGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFL 1090
Query: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH--SGFSGMFCS 1453
C ++ T CQ AG AVKPWR FCP+ CP +S YS+C + C +C SG +G C+
Sbjct: 1091 CRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG--CT 1148
Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIR 1513
RC E CEC+ F+LS CIP CGC H G Y V C E C C S++ +
Sbjct: 1149 TRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSSSGLT 1207
Query: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPC- 1572
CQ C C + C A C S + TFDGA Y L+ C
Sbjct: 1208 CQAAGCPPGRVCEVKAEARNCWAT-RGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP 1266
Query: 1573 -WSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVW 1631
+ Y VV+ G + + VH+ D ++L V +NG RV LP
Sbjct: 1267 GLQNTIPWYRVVAEVQICHG---KTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAE 1323
Query: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
R +L+ G+QV + V V V + + G+LCG CGN++ + +D
Sbjct: 1324 KLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 1382
Score = 137 bits (345), Expect = 1e-31
Identities = 121/423 (28%), Positives = 170/423 (40%), Gaps = 54/423 (12%)
Query: 2323 CVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMD 2380
C+ + C ++GDP Y +FDG + QG YVL T + V +G+ P V +N+
Sbjct: 67 CLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENR 126
Query: 2381 PPRSSIFLQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE-HLRVTLWGQRLYLV 2437
+ +++ V G + + ++ VN A+P + + V + LV
Sbjct: 127 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLV 186
Query: 2438 TDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSW 2497
DF L VS+ ++LPS Y G V GLCGN D+N ND + P+G L ++ +G SW
Sbjct: 187 ADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW 246
Query: 2498 EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQA-CRVLADPQG- 2555
D L +E +G+ C ++L C LA G
Sbjct: 247 RAPGWDPL--------CWDECRGS---------CPTCPEDRLEQYEGPGFCGPLAPGTGG 289
Query: 2556 PFAACHQTVAPEPFQEHCVLDLCSAQDPREQ-------------------EELRCQVLSG 2596
PF CH V PE F + CVLD+C + E+ R QV
Sbjct: 290 PFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVGCE 349
Query: 2597 HGVSSRYHISELYDTLPSILCQPG---RPRGLRGPLRGRLRQHPRLCLQWHPEPPLAD-C 2652
H P+ P P GP + L PL + C
Sbjct: 350 ITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGC 409
Query: 2653 GCTSNGIYYQLGSSFLTE-DCSQRCTCA-SSRILLCEPFSCRAGEVCTL---GNHTQGCF 2707
GC +NG Y++ GS F + CSQ C C L+C P SC GEVC L G H GC
Sbjct: 410 GCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH--GCQ 467
Query: 2708 PES 2710
P S
Sbjct: 468 PVS 470
>gi|134268640 tectorin alpha precursor [Homo sapiens]
Length = 2155
Score = 638 bits (1646), Expect = 0.0
Identities = 436/1499 (29%), Positives = 679/1499 (45%), Gaps = 78/1499 (5%)
Query: 1108 WFSPNCTEHCRCWP-GSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVT 1166
W NCT CRC + + CQ + C + VC+ K + C T+TC+V+G+PHY T
Sbjct: 274 WDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVE-TSTCVVFGEPHYHT 332
Query: 1167 FDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTL 1225
FDG F F G C Y+LA+ C S+ PFF V AKNE + VS + ++ V + + +
Sbjct: 333 FDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILI 392
Query: 1226 LKGR--RTLVGGQQVTLPAIPSKG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSST 1282
KG R V +LP G V + SG ++T+FGL V +DG ++V +
Sbjct: 393 PKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGS 452
Query: 1283 YSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCD 1342
Y CGLCGNY+ N +D L+ DG PA +LG SW+ D +C V N CD
Sbjct: 453 YINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRV-YHADWKCDSGCVDNCTQCD 511
Query: 1343 SSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTM 1402
++ ++ G +CG L T GP C V +F SC+ D+C + LLC +
Sbjct: 512 AATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAY 571
Query: 1403 TTTCQDAGHAVKPWREPHFC--PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEAC 1460
CQ G + WR C + CP S YS+C CPDTC + C+ C E C
Sbjct: 572 ALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGC 631
Query: 1461 ECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGE-RWYKPGCKELCVCESNNRIRCQPWRC 1519
ECN GFVLS +C+P +CGC G Y+ +GE W C C+CE + C C
Sbjct: 632 ECNQGFVLSTSQCVPLHKCGCDFD-GHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTC 690
Query: 1520 RAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDS 1579
+ E C +DG GC + C S + TFDGA + F +Y L + C R +
Sbjct: 691 GSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPEYL 750
Query: 1580 YFVVSATNENRGGILEVSYIKAVHVTVFDLSISL--LRGCKVMLNGHRVALPVWLAQGRV 1637
++ + G ++++ + + V D + + + +V LNG V LP + G++
Sbjct: 751 EIDINKKKPDAG----PAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKL 806
Query: 1638 TIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697
I + N + + + V+Y L+ + + ++Y GLCG YN N+ D+ P+ K
Sbjct: 807 EIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGK 866
Query: 1698 LAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKN---CAILINP-QGPFS 1753
+ +W E G G +C +S + ++ C I+ +P F
Sbjct: 867 CTDNLAVFLESWTTFEEICNG--ECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFL 924
Query: 1754 QCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRC 1812
+CH VV + + +C+ C + G+ + LC S+ YAS C A + WR FCP+ C
Sbjct: 925 ECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLEC 984
Query: 1813 PPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDP 1872
P S + C + C +TC ++ C + C+E C+C +G+ L G+ CV +CGC +
Sbjct: 985 PENSHFEECIT-CTETCETLTLGPICVDS--CSEGCQCDEGYALLGSQCVTRSECGC-NF 1040
Query: 1873 AGSYHPVGERWYTENTCTRLCTCS-VHNNITCFQSTCKPNQICWALDGLLRCRASGVGVC 1931
G E ++ + C C CS N + C CK ++ C GL C+A C
Sbjct: 1041 EGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASC 1100
Query: 1932 QLPGESHYVSFDGSNHSIPDACTLVLVKV-CHPAM-ALPFFKISAKHEKEEGGTEAFRLH 1989
+ G HY++FDG +C L+L P+ + P F ++AK+E + A +
Sbjct: 1101 IVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSL-ALWVK 1159
Query: 1990 EVYIDIYDAQVTLQKG--HRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF 2047
+V + ++ + + + H VL+NS+++ LP +++ S + +V G++V +
Sbjct: 1160 QVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVY 1219
Query: 2048 DGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSC 2107
D L I +P + G+CG +N +D+L MP +A+S +EF SW + D C
Sbjct: 1220 DWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKR--DTFC 1277
Query: 2108 QSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCA 2167
Q D A+ + G + L AA +++C S+++ T F +C
Sbjct: 1278 QVGCGDRCPSCAKVE----GFSKVQQLCSLIPNQNAA-----FSKCHSKVNPTFFYKNCL 1328
Query: 2168 NTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPS 2227
C GG Q C LQ + +TCQ+QG+ WRN + C + CP S Y +C+ C P
Sbjct: 1329 FDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPR 1388
Query: 2228 CWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSG 2287
C + + + + C EGC C GYVL+ C+ CGC P W +S
Sbjct: 1389 CAAIRLKSDCSHY---CVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW-NSD 1444
Query: 2288 CTEKCVC-TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFS 2346
CT +C C IQC +C S C L N C S K+ C G + TFDG
Sbjct: 1445 CTRRCRCFRRNVIQCDPRQCKSDEECALR--NGVRGCFSTKTSYCLAAGGGVFRTFDGAF 1502
Query: 2347 YRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGY----KVQL 2402
R +VL LP+ + L+ +K P +I I+ VY Y ++ +
Sbjct: 1503 LRFPANCAFVLSTICQKLPD-ISFQLIINFDKWSAPNLTI-----ISPVYFYINEEQILI 1556
Query: 2403 QAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDF--ELVVSFGGRKNAVISLPSMY 2460
+ VN ++ VP+ L ++ +LV D ++ + + G IS+
Sbjct: 1557 NDRNTVKVNGTQVNVPFITG--LATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERL 1614
Query: 2461 EGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQG 2520
+ V GLCGN++ + +D + G + SW+ + + + P A E
Sbjct: 1615 QNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKT---NGMQKRPLAPSCNE---- 1667
Query: 2521 AELGLRTGLQVSECSPEQLASNSTQA-CRVLADPQGPFAACHQTVAPEPFQEHCVLDLC 2578
L+ + C + C L D +G F C+ + P PF E C LD C
Sbjct: 1668 ----LQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGC 1722
Score = 559 bits (1440), Expect = e-158
Identities = 375/1294 (28%), Positives = 592/1294 (45%), Gaps = 112/1294 (8%)
Query: 1466 FVLSGLECIPRSQCGCLHPAGSYFKVGER-WYKPGCKELCVC-ESNNRIRCQPWRCRAQE 1523
F + G E P + C G + + GE W C C C + NN I CQ C E
Sbjct: 247 FKVDGKEIDPANGCTS---RGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYE 303
Query: 1524 FCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVV 1583
C + + C A +TC G+PHY TFDG L HF G+C Y+L R C S +F V
Sbjct: 304 VCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSV 363
Query: 1584 SATNENRGGILEVSYIKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRL 1641
A NE+R G VS++K + V V I + +G +V +N +LPV L G V I
Sbjct: 364 EAKNEHRRGSA-VSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQ 422
Query: 1642 SSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGD 1701
S + T+FGL V +DG H ++VP SY CGLCGNYN N LDD LRPD + A
Sbjct: 423 SGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMS 482
Query: 1702 SMQLGAAWKLPESS---EPGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQ 1757
+ LG +W++ + + GC + C + A + + C L GP +C
Sbjct: 483 VLDLGESWRVYHADWKCDSGCV---DNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGT 539
Query: 1758 VVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFC--PMRCPP 1814
VV P + SCV+ C + + T LC+++QAYA +C G WR +T C ++CP
Sbjct: 540 VVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPS 599
Query: 1815 GSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAG 1874
S YS C+S CPDTCS + R+C A PC E CEC +G +LS + CVPL +CGC D G
Sbjct: 600 FSHYSVCTSSCPDTCSDLTASRNC--ATPCTEGCECNQGFVLSTSQCVPLHKCGC-DFDG 656
Query: 1875 SYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLP 1934
Y+ +GE ++ CT C C ++ CF TC ++C DG C VC L
Sbjct: 657 HYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLS 716
Query: 1935 GESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYID 1994
+FDG++++ P + L+K C + +I +K + G R + +
Sbjct: 717 QNQVLHTFDGASYAFPSEFSYTLLKTCPERP--EYLEIDINKKKPDAGPAWLRGLRILVA 774
Query: 1995 IYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLE 2054
+ ++ V +N ++V LP + + + + V K V V++ LL
Sbjct: 775 DQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLY 834
Query: 2055 IEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWK--DKDIDPSCQSLLV 2112
I + TTY+ G+CG +N DE +P+ + ++ + F+ SW ++ + C LL
Sbjct: 835 IRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLL- 893
Query: 2113 DEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAP---VWAQCASRIDLTPFLVDCANT 2169
+ + + R+R +C + P + +C +++T + C
Sbjct: 894 ----------KACNNDSELLKFYRSRSRC-GIINDPSNSSFLECHGVVNVTAYYRTCLFR 942
Query: 2170 LCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCW 2229
LC+ GG LC ++ + + C++ ++ WR FCPLECP S + C+ +C+ +C
Sbjct: 943 LCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECI-TCTETCE 1001
Query: 2230 DLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKS-WVSSGC 2288
L G +C+EGC C GY L +CV RS+CGC + G + ++ WV C
Sbjct: 1002 TL---TLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGC-NFEGHQLATNETFWVDLDC 1057
Query: 2289 TEKCVCTG--GAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFS 2346
C C+G + C C +C + C + C V G YLTFDGF
Sbjct: 1058 QIFCYCSGTDNRVHCETIPCKDDEYCM--EEGGLYYCQARTDASCIVSGYGHYLTFDGFP 1115
Query: 2347 YRLQGRMTYVLIKTVD-VLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAG 2405
+ Q +L T + +V +N+ P ++++++V TV+GY + +
Sbjct: 1116 FDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRA 1175
Query: 2406 LE--LVVNNQKMAVPYRPNE-HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEG 2462
+ ++VN++++ +P + + + + +G + + TDF L V + + I++P +
Sbjct: 1176 YKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQN 1235
Query: 2463 LVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAE 2522
GLCG Y+ N +D+ +P G L ++N FG SW VK + +
Sbjct: 1236 STYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSW-VKRDTF----------------CQ 1278
Query: 2523 LGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLC---- 2578
+G G + C+ + S Q C ++ + F+ CH V P F ++C+ D C
Sbjct: 1279 VG--CGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGG 1336
Query: 2579 ---SAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPS--------ILCQPGRPRGLRG 2627
+A + CQ G V+ + + T P +CQP R +R
Sbjct: 1337 AVQTACSWLQNYASTCQT-QGITVTGWRNYTSCTVTCPPNSHYESCVSVCQP-RCAAIR- 1393
Query: 2628 PLRGRLRQH--------------PRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCS 2673
L+ + + C+ H CGC S+G YY+ F DC+
Sbjct: 1394 -LKSDCSHYCVEGCHCDAGYVLNGKSCILPH------SCGCYSDGKYYEPKQLFWNSDCT 1446
Query: 2674 QRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCF 2707
+RC C ++ C+P C++ E C L N +GCF
Sbjct: 1447 RRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCF 1480
Score = 545 bits (1403), Expect = e-154
Identities = 355/1201 (29%), Positives = 549/1201 (45%), Gaps = 57/1201 (4%)
Query: 1034 TTTSRSSTERCPPNARYESC--ACPASCKSPRPS--CGPLCREGCVCNPGFLFSDNHCIQ 1089
T T ST +CP + Y C +CP +C S C C EGC CN GF+ S + C+
Sbjct: 587 TQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVP 646
Query: 1090 ASSCNCFYNNDYYEPGA-EWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCH 1148
C C ++ YY G W + NCT C C G V C CG+ VC +++G GC
Sbjct: 647 LHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCF 706
Query: 1149 PYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGV 1208
P T CL+ + TFDG + F + +Y L + C P + N+++ G
Sbjct: 707 PKRET-VCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPER--PEYLEIDINKKKPDAGP 763
Query: 1209 SCLSKVYVTLPESTVTL--LKGRRTLVGGQQVTLPAI-PSKGVFLGASGRFVELQTEFGL 1265
+ L + + + + V + + + GQ+V LP PS + + + ++++ +
Sbjct: 764 AWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVV 823
Query: 1266 RVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQD 1325
V++ LY+ +S+TY GLCG Y+ N+ ++ +G + SW T ++
Sbjct: 824 TVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEE 883
Query: 1326 E-DQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVD-THGPFETCLLHVKAASFFDSCML 1383
+ EC ++ + + DS L CG + D ++ F C V +++ +C+
Sbjct: 884 ICNGECG--DLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLF 941
Query: 1384 DMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTC 1443
+C G + LC ++ + C++A V PWR FCP+ CP NS + C C +TC
Sbjct: 942 RLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECI-TCTETC 1000
Query: 1444 HSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKEL 1503
+ G C D C E C+C+ G+ L G +C+ RS+CGC W C+
Sbjct: 1001 ETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIF 1060
Query: 1504 CVCE-SNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562
C C ++NR+ C+ C+ E+C ++ G+Y C A+ A+C SG HYLTFDG F
Sbjct: 1061 CYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQT 1120
Query: 1563 TCTYVLTRPCWSRSQDSY--FVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCK-- 1618
+C +L S DS+ FVV+A NE+R L + ++K V VTVF SI + R K
Sbjct: 1121 SCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLAL-WVKQVDVTVFGYSIVIHRAYKHT 1179
Query: 1619 VMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCG 1678
V++N R+ LP+ L QG++ I V++ T+FGL+V YD + +TVP S G
Sbjct: 1180 VLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYG 1239
Query: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW-KLPESSEPGCFLVGGKPSSCQENSMADA 1737
LCG YN N DD P LA + G +W K + GC G + SC +
Sbjct: 1240 LCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGC---GDRCPSCAKVEGFSK 1296
Query: 1738 WNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAG 1797
+ C+++ N FS+CH V P + +C+ C G C LQ YAS C G
Sbjct: 1297 VQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQG 1356
Query: 1798 -QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHIL 1856
WRN T C + CPP S Y C S C C++I DC C E C C G++L
Sbjct: 1357 ITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHY--CVEGCHCDAGYVL 1414
Query: 1857 SGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWA 1916
+G SC+ CGC Y P W ++ CTR C C N I C CK ++ C
Sbjct: 1415 NGKSCILPHSCGCYSDGKYYEPKQLFWNSD--CTRRCRCFRRNVIQCDPRQCKSDEECAL 1472
Query: 1917 LDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKH 1976
+G+ C ++ C G + +FDG+ P C VL +C + F++
Sbjct: 1473 RNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDIS-FQLIINF 1531
Query: 1977 EKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSI 2036
+K + VY I + Q+ + + V +N QV +P I+ + + SS + +
Sbjct: 1532 DKWSAPNLTI-ISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGL-ATKIYSSEGFLV 1589
Query: 2037 VNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVN 2096
++ +Q+ ++G ++++I I KVCG+CGNFN + D+ + + S
Sbjct: 1590 IDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQ 1649
Query: 2097 SWK-----DKDIDPSCQSLLVDEQQIPAE----QQENPSGNC-RAADLRRAREKCEAALR 2146
SWK + + PSC L + + Q+ G C + D++ + C L
Sbjct: 1650 SWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLL- 1708
Query: 2147 APVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSF 2206
D PF C C +Q LC +L A+G C+S G+ W
Sbjct: 1709 -----------DPLPFYESCYLDGCYSHKKFQ-LCGSLAAYGEACRSFGILSTEWIEKEN 1756
Query: 2207 C 2207
C
Sbjct: 1757 C 1757
Score = 209 bits (533), Expect = 2e-53
Identities = 127/455 (27%), Positives = 202/455 (44%), Gaps = 41/455 (9%)
Query: 1039 SSTERCPPNARYESCA--CPASCKSPR--PSCGPLCREGCVCNPGFLFSDNHCIQASSCN 1094
S T CPPN+ YESC C C + R C C EGC C+ G++ + CI SC
Sbjct: 1367 SCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCG 1426
Query: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154
C+ + YYEP +++ +CT CRC+ + ++C QC + C L+NG GC T+
Sbjct: 1427 CYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFS-TKTS 1485
Query: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKV 1214
CL G + TFDG F C ++L+ C D F++ ++ ++ +S V
Sbjct: 1486 YCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPV 1545
Query: 1215 YVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQ 1274
Y + E + + V G QV +P I + +S F+ + T +++ ++G
Sbjct: 1546 YFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNV 1605
Query: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ----EC 1330
+ +++S K+CGLCGN++G+ +D++ L G P L SW+T+ + + C
Sbjct: 1606 IKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSC 1665
Query: 1331 QKYQVVN-SPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
+ Q + CD+ M G G+C +L D G F+ C + F++SC LD C +
Sbjct: 1666 NELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGC-YS 1724
Query: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSG 1449
+ LC ++ C+ G W E C + PC G
Sbjct: 1725 HKKFQLCGSLAAYGEACRSFGILSTEWIEKENCS---------GVVEDPC--------VG 1767
Query: 1450 MFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
C +R CE G R CGC+ P
Sbjct: 1768 ADCPNR---TCELGNG----------RELCGCIEP 1789
Score = 151 bits (381), Expect = 1e-35
Identities = 129/488 (26%), Positives = 191/488 (39%), Gaps = 56/488 (11%)
Query: 2283 WVSSGCTEKCVCT--GGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYL 2340
W CT KC C I C + C C+ C + ++ C V+G+P Y
Sbjct: 274 WDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCE--PKGKFFYCSAVETSTCVVFGEPHYH 331
Query: 2341 TFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV 2400
TFDGF + QG Y+L + + + VE +N+ + +++E+ V GYK+
Sbjct: 332 TFDGFLFHFQGSCAYLLARQC-LQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKI 390
Query: 2401 QLQAGL--ELVVNNQKMAVPYRPN-EHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLP 2457
+ G + VN+ ++P + +++ G + TDF L+V+F G+ A IS+P
Sbjct: 391 LIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVP 450
Query: 2458 SMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEE 2517
Y GLCGNY+KN +D + P G ++ G SW V D
Sbjct: 451 GSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHAD-------------- 496
Query: 2518 GQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDL 2577
+ G + + E L S C L GP C V P F CV DL
Sbjct: 497 -WKCDSGCVDNCTQCDAATEALYFGSDY-CGFLNKTDGPLWECGTVVDPTAFVHSCVYDL 554
Query: 2578 CSAQDPREQEELRCQVLSGHGV------------------------SSRYHISELYDTLP 2613
CS +D L CQ + + + S H S + P
Sbjct: 555 CSVRD---NGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCP 611
Query: 2614 SILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSSF-LTEDC 2672
R P + L PL CGC +G YY +G F T +C
Sbjct: 612 DTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANC 671
Query: 2673 SQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFP--ESPCLQNPCQNDGQCREQGATF 2730
+ +C C + C +C +GEVC + + QGCFP E+ CL + QN GA++
Sbjct: 672 TVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLS--QNQVLHTFDGASY 729
Query: 2731 TCECEVGY 2738
E Y
Sbjct: 730 AFPSEFSY 737
>gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1472
Score = 555 bits (1429), Expect = e-157
Identities = 313/860 (36%), Positives = 433/860 (50%), Gaps = 24/860 (2%)
Query: 1127 CQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPC 1186
C+ QC CQ+ G+ GC + TA C GDPHY TFDGR + MG C+Y + + C
Sbjct: 505 CEGMQCAAGQRCQVVGGKAGCVAES-TAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
Query: 1187 G-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRR--TLVGGQQVTLPAI 1243
+ T P F V AKNE +G VS + V V +V+L +G LV Q+ LP
Sbjct: 564 SEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 623
Query: 1244 PSKG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDH 1302
S+G + + SG ++ FGL V +D D QL +++ + + ++CGLCGNY+G+ +D
Sbjct: 624 LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 683
Query: 1303 LKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTH 1362
L DG+ A D E +SW+ D D D C+ N P+C G CG L
Sbjct: 684 LTPDGALAPDAVEFASSWKLD-DGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 742
Query: 1363 GPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFC 1422
GPF C + F + C+ D+C G + LC +S C + G +V WR P C
Sbjct: 743 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 802
Query: 1423 PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR-CVEACECNPGFVLSGLECIPRSQCGC 1481
P++CP NS+Y LC CP +C+ + CS R CVE C C PGFV SG C+P S CGC
Sbjct: 803 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 862
Query: 1482 LHPAGSYFKVGERWYKPGCKELCVCE-SNNRIRCQPWR-CRAQEFCGQQDGIYGCHAQGA 1539
E W C+ C C + +++ C+ + C A E C Q+G+ GC+
Sbjct: 863 TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 922
Query: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYI 1599
TC SGDPHY++FDG FMGTCTY+L C + F V NE+RG VSY
Sbjct: 923 GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGS-QTVSYT 981
Query: 1600 KAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVR 1657
+AV V + +++ R +V+++ LP A G+V + ++ T+FGL V
Sbjct: 982 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 1041
Query: 1658 YDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEP 1717
YD + V VPSSY LCGLCGN+N + DD A +++ G +W+ E + P
Sbjct: 1042 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ--EETRP 1099
Query: 1718 GCFLVGGKPSSCQENSMADA---WNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
GC +P C + A +KN C IL +P+GPF +CH + PQ + CV+ +C
Sbjct: 1100 GCGAT--EPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRC 1157
Query: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
G + LC +L YA+ C AG WR+ CP+ CPP S Y CS CP +C +
Sbjct: 1158 LLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDL 1217
Query: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
P C C E C C +G LSG SC+PL CGC G+YHP G+ +Y C L
Sbjct: 1218 PVPGGC--GSECHEGCVCDEGFALSGESCLPLASCGCVH-QGTYHPPGQTFYPGPGCDSL 1274
Query: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
C C ++C S+C P++ C G L C A G CQ G+ HY +FDG
Sbjct: 1275 CHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGT 1334
Query: 1953 CTLVLVKVCHPAMALPFFKI 1972
C VL + C L F +
Sbjct: 1335 CVYVLAQTCGTRPGLHRFAV 1354
Score = 475 bits (1223), Expect = e-133
Identities = 287/869 (33%), Positives = 416/869 (47%), Gaps = 43/869 (4%)
Query: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCW 1573
C+ +C A + C G GC A+ A C A GDPHY TFDG + MGTC+Y + C
Sbjct: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 564
Query: 1574 SRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCK--VMLNGHRVALPVW 1631
F V A NE+RG VSY+ V V + S+SL RG V+++ R LPV
Sbjct: 565 EDDTLPAFSVEAKNEHRGS-RRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 623
Query: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDN 1691
L++GR+ + S ++ FGL V YD + +++P+ + Q+CGLCGNYN + DD
Sbjct: 624 LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 683
Query: 1692 LRPDRKLAGDSMQLGAAWKLPESS---EPGCFLVGGKPSSCQENSMADAWNKNCAILINP 1748
L PD LA D+++ ++WKL + E GC P+ + ++ C +L
Sbjct: 684 LTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTKL 741
Query: 1749 QGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPA-WRNRTF 1807
GPF+ CH + P+ CV+ C G+ +LCR L AYA C + G + WR+
Sbjct: 742 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 801
Query: 1808 CPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC 1867
CP+ CP S Y C CP +C+ P +C PC E C C G + SG +CVP C
Sbjct: 802 CPLSCPANSRYELCGPACPTSCNGAAAPSNC-SGRPCVEGCVCLPGFVASGGACVPASSC 860
Query: 1868 GCTDPAGSYHPVGERWYTENTCTRLCTCS-VHNNITCF-QSTCKPNQICWALDGLLRCRA 1925
GCT P E W E C R CTC+ + +TC + +C + C +GLL C
Sbjct: 861 GCTFQGLQLAPGQEVWADE-LCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 919
Query: 1926 SGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEA 1985
G CQ G+ HYVSFDG CT +LV C ALP F++ ++E T +
Sbjct: 920 DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS 979
Query: 1986 FRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGV 2043
+ V ++ +V +++ + +VL++ LP + V V ++V G+
Sbjct: 980 YT-RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGL 1038
Query: 2044 QVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDI 2103
V +D N + ++P++Y +CG+CGNFN + D+L + A + F NSW++ +
Sbjct: 1039 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQE-ET 1097
Query: 2104 DPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCE--AALRAPVWAQCASRIDLTP 2161
P C + E + P + A +++ +C A + P + +C S++D
Sbjct: 1098 RPGCGA---------TEPGDCPKLDSLVAQQLQSKNECGILADPKGP-FRECHSKLDPQG 1147
Query: 2162 FLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCL 2221
+ DC C G LC AL + A CQ+ G WR+ CPL CP +S Y C
Sbjct: 1148 AVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACS 1207
Query: 2222 PSCSPSCWDL--DGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSI-P 2278
C SC DL G C S C EGC+C G+ LS + C+P + CGC H G+ P
Sbjct: 1208 YGCPLSCGDLPVPGGC-----GSECHEGCVCDEGFALSGESCLPLASCGC--VHQGTYHP 1260
Query: 2279 LGKS-WVSSGCTEKCVC-TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGD 2336
G++ + GC C C GG + C C CQ + CV+ S C GD
Sbjct: 1261 PGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQ--PSGGSLGCVAVGSSTCQASGD 1318
Query: 2337 PRYLTFDGFSYRLQGRMTYVLIKTVDVLP 2365
P Y TFDG + G YVL +T P
Sbjct: 1319 PHYTTFDGRRFDFMGTCVYVLAQTCGTRP 1347
Score = 384 bits (986), Expect = e-106
Identities = 228/631 (36%), Positives = 309/631 (48%), Gaps = 19/631 (3%)
Query: 1017 MSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESC--ACPASCK---SPRPSCGPLCR 1071
+S +A + + +G + + CP N+RYE C ACP SC +P G C
Sbjct: 779 LSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCV 838
Query: 1072 EGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQI 1129
EGCVC PGF+ S C+ ASSC C + PG E W C C C + +V C+
Sbjct: 839 EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 898
Query: 1130 SQ-CGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCG- 1187
Q C C ++NG GC+P TC GDPHYV+FDGR F FMG CTY+L CG
Sbjct: 899 KQSCPAGERCSVQNGLLGCYPDR-FGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQ 957
Query: 1188 NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR--RTLVGGQQVTLPAIPS 1245
N+ P FRV +NE +G + VS V V V + + + LV LP +
Sbjct: 958 NAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAA 1017
Query: 1246 KG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLK 1304
G V + GR ++T+FGL V +D + ++ V S+Y+ LCGLCGN++G+ +D
Sbjct: 1018 DGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLAL 1077
Query: 1305 LDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP 1364
G A + GNSWQ ++ C + + P DS + + CG L D GP
Sbjct: 1078 RGGGQAANALAFGNSWQ--EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGP 1135
Query: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
F C + C+ D C G LC ++T CQ AG V PWR CP+
Sbjct: 1136 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL 1195
Query: 1425 ACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
+CPP+S Y C+ CP +C C C E C C+ GF LSG C+P + CGC+H
Sbjct: 1196 SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQ 1255
Query: 1485 AGSYFKVGERWYK-PGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCT 1543
G+Y G+ +Y PGC LC C+ + C+ C E C G GC A G++TC
Sbjct: 1256 -GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQ 1314
Query: 1544 ASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAV 1602
ASGDPHY TFDG FMGTC YVL + C +R F V N G G + V+ + V
Sbjct: 1315 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 1374
Query: 1603 HVTVFDLSISLLR-GCKVMLNGHRVALPVWL 1632
V F L + + V +G + A +W+
Sbjct: 1375 QVANFTLRLEQRQWKVTVRADGEQGARGLWV 1405
Score = 323 bits (829), Expect = 1e-87
Identities = 235/847 (27%), Positives = 357/847 (42%), Gaps = 87/847 (10%)
Query: 1902 TCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVC 1961
+C C Q C + G C A VC+ G+ HY +FDG + + C+ +V++C
Sbjct: 504 SCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
Query: 1962 HPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHR--VLINSKQVTLPA 2019
LP F + AK+E G + V + Y V+L +G VL+++++ LP
Sbjct: 564 SEDDTLPAFSVEAKNE-HRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
Query: 2020 ISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDE 2079
+ V S ++V + G+ V +D + L + +P + +VCG+CGN+N + D+
Sbjct: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
Query: 2080 LMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPA---EQQENPSGNCRAADLRR 2136
+ P +A EF +SWK D D C+ + PA Q ++ G+ L +
Sbjct: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTK 740
Query: 2137 AREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGL 2196
L P +A C +D PFL C LC GG +LC+ L A+ C G+
Sbjct: 741 --------LDGP-FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGI 791
Query: 2197 KPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPS-----ACAEGCICQ 2251
WR+ + CPL CPA S Y C P+C S C GA PS C EGC+C
Sbjct: 792 SVGDWRSPANCPLSCPANSRYELCGPACPTS-------CNGAAAPSNCSGRPCVEGCVCL 844
Query: 2252 PGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGA--IQCGDFR-CPS 2308
PG+V S CVP S CGC P + W C +C C G + C D + CP+
Sbjct: 845 PGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPA 904
Query: 2309 GSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVD---VLP 2365
G C + N C D+ C GDP Y++FDG + G TY+L+ + LP
Sbjct: 905 GERCSV--QNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALP 962
Query: 2366 EGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE 2423
+LVE ++ S + + V G KV ++ +++V++ +P++ +
Sbjct: 963 --AFRVLVENEHRGSQTVS--YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAAD 1018
Query: 2424 -HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLP 2482
++V G+ + TDF L V++ +PS Y + GLCGN++ + +D+ L
Sbjct: 1019 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1078
Query: 2483 SGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASN 2542
G N FGNSW+ +T A E G +L Q+
Sbjct: 1079 GGGQAANALAFGNSWQEETRP-------GCGATEPGDCPKLDSLVAQQL----------Q 1121
Query: 2543 STQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSR 2602
S C +LADP+GPF CH + P+ CV D C P + L C L+ + + +
Sbjct: 1122 SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL--PGQSGPL-CDALATYAAACQ 1178
Query: 2603 YHISELY----DTLPSILCQPGR------------------PRGLRGPLRGRLRQHPRLC 2640
+ ++ + L + C P P G
Sbjct: 1179 AAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFA 1238
Query: 2641 LQWHPEPPLADCGCTSNGIYYQLGSSFLT-EDCSQRCTCASSRILLCEPFSCRAGEVCTL 2699
L PLA CGC G Y+ G +F C C C ++ CE SC E C
Sbjct: 1239 LSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQP 1298
Query: 2700 GNHTQGC 2706
+ GC
Sbjct: 1299 SGGSLGC 1305
Score = 160 bits (404), Expect = 2e-38
Identities = 131/454 (28%), Positives = 191/454 (42%), Gaps = 62/454 (13%)
Query: 2301 CGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKT 2360
C +C +G CQ+ + CV++ + C GDP Y TFDG Y + G +Y +++
Sbjct: 505 CEGMQCAAGQRCQVVG--GKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL 562
Query: 2361 V---DVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLE--LVVNNQKM 2415
D LP VE +N+ R ++ V Y + V L G ++V+NQ+
Sbjct: 563 CSEDDTLPA----FSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRS 618
Query: 2416 AVPYRPNE-HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKN 2474
+P +E LRV G R + F LVV++ +SLP+ ++ V GLCGNY+ +
Sbjct: 619 RLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGD 678
Query: 2475 RKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSEC 2534
+D + P GAL + F +SW++ D L E G + C
Sbjct: 679 PADDFLTPDGALAPDAVEFASSWKLDDGDYL---------------CEDGCQNNCPA--C 721
Query: 2535 SPEQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQV 2593
+P Q + C +L GPFA CH T+ P PF E CV DLC R C+
Sbjct: 722 TPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLS---LCRG 778
Query: 2594 LSGH-------GVSSRYHISELYDTLPSI------LCQPGRPRGLRGPLR-----GRLRQ 2635
LS + G+S S L LC P P G GR
Sbjct: 779 LSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCV 838
Query: 2636 HPRLCLQWHPEP-----PLADCGCTSNGIYYQLGSSFLTED-CSQRCTC--ASSRILLCE 2687
+CL P + CGCT G+ G ++ C +RCTC A+ ++ +
Sbjct: 839 EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 898
Query: 2688 PFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDG 2721
SC AGE C++ N GC+P+ CQ G
Sbjct: 899 KQSCPAGERCSVQNGLLGCYPDR---FGTCQGSG 929
>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
Length = 2013
Score = 366 bits (940), Expect = e-100
Identities = 337/1279 (26%), Positives = 511/1279 (39%), Gaps = 208/1279 (16%)
Query: 1148 HPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEG 1207
+P C +G HY TFDG F F G C Y+ ++ CG + + F +++E
Sbjct: 73 NPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESA--- 129
Query: 1208 VSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRV 1267
LS+V + + + L KG LV G V LP S GV + S + +++ GL +
Sbjct: 130 APTLSRVLMKVDGVVIQLTKGS-VLVNGHPVLLPFSQS-GVLIQQSSSYTKVEARLGLVL 187
Query: 1268 RWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDED 1327
W+ D L + + + Y+ K CGLCG+++G L L + E GN + D D
Sbjct: 188 MWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSEL-LSHNTKLTPMEFGNLQKMD-DPT 245
Query: 1328 QECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLDMC 1386
++CQ V P + S +G G C L+ HG F C+ V S+ ++C D+C
Sbjct: 246 EQCQ--DPVPEPPRNCS-----TGFGICEELL--HGQLFSGCVALVDVGSYLEACRQDLC 296
Query: 1387 GFQGLQHL--LCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH 1444
+ L +C ++ + C AG + WR P FCP CP N +Y C PC DTC
Sbjct: 297 FCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCS 356
Query: 1445 SGFSGMFCSDRCVEACECNPGFVLSGLE---CIPRSQCGCLHPAGSYFKVGERWYKPGCK 1501
+ C D CV C C G VL + C+P S+C C++ +Y Y C
Sbjct: 357 NQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGAT--YSTDCT 414
Query: 1502 ELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFM 1561
C C S R CQ C TC+ G H+ TFDG +
Sbjct: 415 N-CTC-SGGRWSCQEVPC-------------------PGTCSVLGGAHFSTFDGKQYTVH 453
Query: 1562 GTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLS--ISLLRGCKV 1619
G C+YVLT+PC S S F V A G + +K+V +++ + + + +V
Sbjct: 454 GDCSYVLTKPCDS----SAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEV 509
Query: 1620 MLNGHRVALPVWLAQGRVTI-RLSSNLVLLYTNFGLQVRYDGSHLVEV--TVPSSYGGQL 1676
LN LP+ A VTI R S+ ++ T+ GLQ+ +++ + GQ
Sbjct: 510 FLNQIYTQLPISAAN--VTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQT 567
Query: 1677 CGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGK-----PSSCQE 1731
CGLCGN+N+ DD R L+G AA+ ++ C + S +
Sbjct: 568 CGLCGNFNSIQADDF----RTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVEN 623
Query: 1732 NSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYAS 1791
A W C+ L + GPF +CH V P + +++C+ C + LC +L +Y
Sbjct: 624 EKYAQHW---CSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVH 680
Query: 1792 LCAQAG-QAPAWRNRTFC-PMR-CPPGSSYSPCSSPCPDTCSSINNPR-DCPKALPCAES 1847
CA G Q WR+ PM CP +Y S C TC S++ C +
Sbjct: 681 ACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDG 740
Query: 1848 CECQKGHILSGTS-CVPLGQCGCTDPAGSYHPVGERWYTEN---TCTRL----------- 1892
C C KG L T CV C C GS P GE + TCT
Sbjct: 741 CICPKGTFLDDTGKCVQASNCPCYH-RGSMIPNGESVHDSGAICTCTHGKLSCIGGQAPA 799
Query: 1893 -----------------------CTCSVHN-NITCFQSTCKPNQICWALDGLLRCRASG- 1927
C S H ++TC+ C P +C DGL+ G
Sbjct: 800 PVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVC--PDGLVADGEGGC 857
Query: 1928 ------------------------------------------VGVCQLPGESHYVSFDGS 1945
+ C + G+ HY++FDG
Sbjct: 858 ITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQ 917
Query: 1946 NHSIPDACTLVLVKV-C--HPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTL 2002
++S C LV+ C + F ++ GT + ++++ ++ +++
Sbjct: 918 SYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSH 977
Query: 2003 QKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYY 2062
K + + Q ++P +++ IY +V+ IG+ + +D + I + +
Sbjct: 978 GKVEVIGTDESQ-------EVP-YTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFK 1029
Query: 2063 GKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQ 2122
G+VCG+CGNF+D ++ S V EF NSWK + PSC L
Sbjct: 1030 GRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWK---LSPSCPDALA---------- 1076
Query: 2123 ENPSGNCRAADLRR--AREKCEAALRAPVWAQCASRIDLTPFLVDCAN--TLCEFGGLYQ 2178
P C A R+ A+++C + L P +A C + ++ + C N C+ GG +
Sbjct: 1077 --PKDPCTANPFRKSWAQKQC-SILHGPTFAACHAHVEPARYYEACVNDACACDSGGDCE 1133
Query: 2179 ALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS-------SYTNCLPSCSPSCWDL 2231
C A+ A+ C GL WR S CPL C Y+ Y C C +C +
Sbjct: 1134 CFCTAVAAYAQACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNP 1192
Query: 2232 DGRCEGAKVPSACAEGCI--CQP-GYVLSEDKCVPRSQCGCK------DAHGGSIPLGKS 2282
G C EGC C P + EDK + C HG S G
Sbjct: 1193 RGDC---LRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAV 1249
Query: 2283 WVSSGCTEKCVCTGGAIQC 2301
S + C+CT ++C
Sbjct: 1250 VPSDKNCQSCLCTERGVEC 1268
Score = 292 bits (747), Expect = 4e-78
Identities = 285/1146 (24%), Positives = 448/1146 (39%), Gaps = 197/1146 (17%)
Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
A C+ G HY TFDG + F G C YV + C + +D + + E+ L
Sbjct: 75 AHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLS 134
Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQ 1655
+K V I L +G V++NGH V LP +Q V I+ SS+ + GL
Sbjct: 135 RVLMKVDGVV-----IQLTKG-SVLVNGHPVLLP--FSQSGVLIQQSSSYTKVEARLGLV 186
Query: 1656 VRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSL-DDNLRPDRKLAGDSMQLGAAWKLPES 1714
+ ++ + + + + Y + CGLCG++N + + L + KL M+ G K+ +
Sbjct: 187 LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMDDP 244
Query: 1715 SEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG 1774
+E V P +C C L++ Q FS C +V S +C C
Sbjct: 245 TEQCQDPVPEPPRNCSTGFGI------CEELLHGQ-LFSGCVALVDVGSYLEACRQDLCF 297
Query: 1775 TKGDTTAL---CRSLQAYASLCAQAGQAPA-WRNRTFCPMRCPPGSSYSPCSSPCPDTCS 1830
+ DT L C +L Y+ C AG P WR FCP +CP Y C SPC DTCS
Sbjct: 298 CE-DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCS 356
Query: 1831 SINNPRDCPKALPCAESCECQKGHILSG---TSCVPLGQCGCTDPAGSYHPVGERWYTEN 1887
+ + R C C C C +G +L T CVP+ +C C +Y P G + T+
Sbjct: 357 NQEHSRACEDH--CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP-GATYSTD- 412
Query: 1888 TCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNH 1947
CT CTCS +C + C G C + G +H+ +FDG +
Sbjct: 413 -CTN-CTCS-GGRWSCQEVPCP-------------------GTCSVLGGAHFSTFDGKQY 450
Query: 1948 SIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQ--VTLQKG 2005
++ C+ VL K C + F + A+ + L V + + Q V ++
Sbjct: 451 TVHGDCSYVLTKPCDSSA----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKAS 506
Query: 2006 HRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEI--EIPTTYYG 2063
V +N LP IS + S+ + I +G+Q+ +++ ++ G
Sbjct: 507 GEVFLNQIYTQLP-ISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRG 565
Query: 2064 KVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQE 2123
+ CG+CGNFN + D+ S V + + F N++K + P+ ++ D + E ++
Sbjct: 566 QTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVENEK 625
Query: 2124 NPSGNC-RAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQ 2182
C + D +C AA++ + +C C LC
Sbjct: 626 YAQHWCSQLTDADGPFGRCHAAVKPGTYYS------------NCMFDTCNCERSEDCLCA 673
Query: 2183 ALQAFGATCQSQGLKPPLWRNSSFCP--LECPAYSSYTNCLPSCSPSCWDL---DGRCEG 2237
AL ++ C ++G++ WR+ CP +Y + +C P+C L D C
Sbjct: 674 ALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSV 733
Query: 2238 AKVPSACAEGCICQPGYVLSED-KCVPRSQCGC----------KDAH------------- 2273
+P +GCIC G L + KCV S C C + H
Sbjct: 734 GFIP---VDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKL 790
Query: 2274 ---GGSIP-------------------------------LGKSWVSSGCTEKCVCTGGAI 2299
GG P L + S C CVC G +
Sbjct: 791 SCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLV 850
Query: 2300 QCGDFRCPSGSHCQL--------------------TSDNSNSNCVSDKS-EQCSVYGDPR 2338
G+ C + C T D+ C D C+VYGD
Sbjct: 851 ADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGH 910
Query: 2339 YLTFDGFSYRLQGRMTYVLIKT-VDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYG 2397
YLTFDG SY G Y L++ + V N + + + + G
Sbjct: 911 YLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGG 970
Query: 2398 YKVQLQAG-LELVVNNQKMAVPYRPNEHLRVTLWGQRLYLV--TDFELVVSFGGRKNAVI 2454
++++L G +E++ ++ VPY T+ +YLV TD LV+ + + + I
Sbjct: 971 FELKLSHGKVEVIGTDESQEVPY--------TIRQMGIYLVVDTDIGLVLLWDKKTSIFI 1022
Query: 2455 SLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPA 2514
+L ++G V GLCGN+D ND S ++ ++ FGNSW++ P A+
Sbjct: 1023 NLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPS-----CPDALAP 1077
Query: 2515 EEEGQGAELGLRTGLQVSECSPEQLASNSTQ-ACRVLADPQGPFAACHQTVAPEPFQEHC 2573
++ C+ + Q C +L P FAACH V P + E C
Sbjct: 1078 KD----------------PCTANPFRKSWAQKQCSILHGP--TFAACHAHVEPARYYEAC 1119
Query: 2574 VLDLCS 2579
V D C+
Sbjct: 1120 VNDACA 1125
Score = 193 bits (490), Expect = 2e-48
Identities = 221/893 (24%), Positives = 324/893 (36%), Gaps = 166/893 (18%)
Query: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
VC G HY +FDG P C V + C A F I + +E A L
Sbjct: 80 VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHC--GAAYEDFNIQLRRSQESA---APTLS 134
Query: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049
V + + + L KG VL+N V LP SQ GV ++ SS Y+ V ++G+ + ++
Sbjct: 135 RVLMKVDGVVIQLTKGS-VLVNGHPVLLP-FSQ-SGVLIQQSSSYTKVEARLGLVLMWNH 191
Query: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQS 2109
+ L +E+ T Y K CG+CG+FN ++ S + EF N K D CQ
Sbjct: 192 DDSLLLELDTKYANKTCGLCGDFNGMPVVSELL-SHNTKLTPMEFGNLQKMDDPTEQCQD 250
Query: 2110 LLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANT 2169
+ + P NC CE L +++ C + +D+ +L C
Sbjct: 251 PVPE-----------PPRNCSTGF-----GICEELLHGQLFSGCVALVDVGSYLEACRQD 294
Query: 2170 LC--EFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPS 2227
LC E L +C L + C G P WR FCP +CP Y C C+ +
Sbjct: 295 LCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADT 354
Query: 2228 CWDLDGR--CEGAKVPSACAEGCICQPGYVLSE---DKCVPRSQCGCKDAHGGSIPLGKS 2282
C + + CE C GC C G VL + CVP S+C C + G+ +
Sbjct: 355 CSNQEHSRACE-----DHCVAGCFCPEGTVLDDIGQTGCVPVSKCAC--VYNGAAYAPGA 407
Query: 2283 WVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTF 2342
S+ CT C C+GG C + CP CSV G + TF
Sbjct: 408 TYSTDCTN-CTCSGGRWSCQEVPCPG---------------------TCSVLGGAHFSTF 445
Query: 2343 DGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYK--V 2400
DG Y + G +YVL K D +L E R + S L+ V ++ G + V
Sbjct: 446 DGKQYTVHGDCSYVLTKPCD---SSAFTVLAELR-RCGLTDSETCLKSVTLSLDGVQTVV 501
Query: 2401 QLQAGLELVVNNQKMAVP--------YRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNA 2452
++A E+ +N +P +RP+ + L L + +LV +
Sbjct: 502 VIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQL--NLQLVPTM----QL 555
Query: 2453 VISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAI 2512
+ L G GLCGN++ + +D SG + F N+++
Sbjct: 556 FMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT------------- 602
Query: 2513 PAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEH 2572
Q A +R + + + C L D GPF CH V P + +
Sbjct: 603 ------QAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSN 656
Query: 2573 CVLDLCSAQDPREQEELRCQVLSGH----------------GVSSR------------YH 2604
C+ D C+ + E+ C LS + GV ++ YH
Sbjct: 657 CMFDTCNCE---RSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYH 713
Query: 2605 ISELYDTLPS-----ILCQPG--RPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSN 2657
+S T S I C G G P +G C+Q ++C C
Sbjct: 714 VSTCQPTCRSLSEGDITCSVGFIPVDGCICP-KGTFLDDTGKCVQ------ASNCPCYHR 766
Query: 2658 GIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGE----VCTLGNHTQGCFPESP-- 2711
G G S D CTC ++ SC G+ VC C +P
Sbjct: 767 GSMIPNGES--VHDSGAICTCTHGKL------SCIGGQAPAPVCAAPMVFFDCRNATPGD 818
Query: 2712 ----CLQNPCQNDGQCREQGATFTCECEVGY---GGGLCMEPRDAPPPRKPAS 2757
C ++ D C C C G G G C+ D P AS
Sbjct: 819 TGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEAS 871
Score = 180 bits (457), Expect = 2e-44
Identities = 140/492 (28%), Positives = 207/492 (42%), Gaps = 54/492 (10%)
Query: 1042 ERCPPNARYESCACPAS--CKSPRPS--CGPLCREGCVCNPGFLFSD---NHCIQASSCN 1094
++CP N +Y C P + C + S C C GC C G + D C+ S C
Sbjct: 336 QKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCA 395
Query: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154
C YN Y PGA +S +CT +C C G R CQ C
Sbjct: 396 CVYNGAAYAPGAT-YSTDCT-NCTC-SGGRWSCQEVPC--------------------PG 432
Query: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG-QEGVSCLSK 1213
TC V G H+ TFDG+ + G C+Y+L +PC +S F V A+ G + +CL
Sbjct: 433 TCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSA---FTVLAELRRCGLTDSETCLKS 489
Query: 1214 VYVTLP-ESTVTLLKGRRTLVGGQQVT-LPAIPSKGVFLGASGRFVELQTEFGLRVRWD- 1270
V ++L TV ++K + Q T LP + S F+ QT GL++
Sbjct: 490 VTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQL 549
Query: 1271 -GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQE 1329
QL++ ++ G+ CGLCGN++ +D L G N+++T
Sbjct: 550 VPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT----QAA 605
Query: 1330 CQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
C + C S+++ +C +L D GPF C VK +++ +CM D C +
Sbjct: 606 CPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCE 665
Query: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFC--PM-ACPPNSKYSLCAKPCPDTCHSG 1446
+ LC +S+ C G + WR+ C PM CP + Y C TC S
Sbjct: 666 RSEDCLCAALSSYVHACAAKGVQLGGWRD-GVCTKPMTTCPKSMTYHYHVSTCQPTCRSL 724
Query: 1447 FSG-MFCSDRC--VEACECNPGFVLSGL-ECIPRSQCGCLHPAGSYFKVGERWYKPGCKE 1502
G + CS V+ C C G L +C+ S C C H GS GE + G
Sbjct: 725 SEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYH-RGSMIPNGESVHDSGA-- 781
Query: 1503 LCVCESNNRIRC 1514
+C C ++ ++ C
Sbjct: 782 ICTC-THGKLSC 792
Score = 170 bits (431), Expect = 2e-41
Identities = 149/530 (28%), Positives = 211/530 (39%), Gaps = 85/530 (16%)
Query: 1055 CPASCKSPRPSC-GPLCREGCVCNPGFLFS-DNHCIQASSCNCFYNNDYYEPGAEWFSPN 1112
C SC + +C P C GCVC G + + CI A C C +N Y G
Sbjct: 823 CQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQT----- 877
Query: 1113 CTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHF 1172
RV C C + + C ATC VYGD HY+TFDG+ +
Sbjct: 878 ----------IRVGCNTCTCDSR--------MWRCTDDPCLATCAVYGDGHYLTFDGQSY 919
Query: 1173 GFMGKCTYILAQP-CG--NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR 1229
F G C Y L Q CG +ST FRV +N G G +C + + L + L G+
Sbjct: 920 SFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGK 979
Query: 1230 RTLVG---GQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGK 1286
++G Q+V I G++L + T+ GL + WD +++ +S + G+
Sbjct: 980 VEVIGTDESQEVPY-TIRQMGIYL-------VVDTDIGLVLLWDKKTSIFINLSPEFKGR 1031
Query: 1287 LCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQ 1346
+CGLCGN+D + ND S GD E GNSW+ C P + +
Sbjct: 1032 VCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL----SPSCPDALAPKDPCTANPFR 1087
Query: 1347 SSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLDMCGFQ--GLQHLLCTHMSTMT 1403
S + C L HGP F C HV+ A ++++C+ D C G CT ++
Sbjct: 1088 KSWAQKQ-CSIL---HGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYA 1143
Query: 1404 TTCQDAGHAVKPWREPHFCPMACP---PNSK----YSLCAKPCPDTCHSGFSGMFCSDRC 1456
C + G V WR P CP+ C P + Y C PC TC +
Sbjct: 1144 QACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWG 1202
Query: 1457 VEAC--ECNPG---FVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNR 1511
+E C +C P F ++C+ L P V + Y+PG V S+
Sbjct: 1203 LEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPR---CHVHGKSYRPG----AVVPSDK- 1254
Query: 1512 IRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTAS------GDPHYLTFDG 1555
CQ C + G+ + A CT + GD Y T DG
Sbjct: 1255 -NCQSCLC-------TERGVECTYKAEACVCTYNGQRFHPGDVIYHTTDG 1296
Score = 52.0 bits (123), Expect = 8e-06
Identities = 85/355 (23%), Positives = 125/355 (35%), Gaps = 39/355 (10%)
Query: 620 TIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPT 679
T+ + +PT PT + T + P+ STE+PT + T T T + PV
Sbjct: 1686 TVATTRPT---PHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRN 1742
Query: 680 EKPSIPTEK---PSIPTEKPTISMEET----IISTEKPTISPEKPTIPTEKPTIPTEKST 732
P K P+ P +ET I S EK PE E +
Sbjct: 1743 CHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPE-------------EITR 1789
Query: 733 ISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPT-IPT 791
+ + P + S E+ + P K+ + E + E P P
Sbjct: 1790 LQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPV 1849
Query: 792 EKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPT 851
++ P+TP+ T+ S + TTT V +T ST + + T
Sbjct: 1850 TSTPVTA--PSTPSGRAISPTQSTS------SWQKSRTTTLVTTSTTSTPQTSTTYAHTT 1901
Query: 852 ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911
+T PT T + P + P P+ +TIS +I + T +
Sbjct: 1902 STTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTS 1961
Query: 912 KPTIS-TEKPTIPTEKPTIPTEETTIS--TEKLTIPTEKPTISPEKLTIPTEKPT 963
PT S T PT T + PT TT S T + PT T P T P+ PT
Sbjct: 1962 APTSSTTSAPT--TSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPG--TTPSPVPT 2012
Score = 49.7 bits (117), Expect = 4e-05
Identities = 52/178 (29%), Positives = 69/178 (38%), Gaps = 20/178 (11%)
Query: 531 PGTCPVKVLPELPP-------VSPVSSTG---PSETTGLTENPTISTKKPTVSIEKPSVT 580
P CPV P P +SP ST S TT L T ST + + + + T
Sbjct: 1844 PRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTST 1903
Query: 581 TEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKP 640
T PT + PT + T S + S N PS PT TI +I S
Sbjct: 1904 TSAPTA--RTTSAPTTR-TTSASPASTTSGPGNTPSPVPT----TSTISAPTTSITSAPT 1956
Query: 641 TIPSEKPTISTEKPTVPTEEPTT-PTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPT 697
T + PT ST + PT T+ PT TT+S + S + + P+ PT
Sbjct: 1957 TSTTSAPTSST--TSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPVPT 2012
Score = 47.0 bits (110), Expect = 3e-04
Identities = 47/167 (28%), Positives = 63/167 (37%), Gaps = 14/167 (8%)
Query: 608 PSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE-PTTPTE 666
P P+ PS + P++ + + T + S T +T T T PT T
Sbjct: 1853 PVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTT 1912
Query: 667 ETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPT-----IPT 721
T+ P S P PS TIS T I++ T + PT PT
Sbjct: 1913 SAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPT 1972
Query: 722 EKPT-IPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPT 767
T PT +T SP+ TT + PT T P TTP+ PT
Sbjct: 1973 TSTTSAPTSSTTSSPQTSTT-----SAPTTSTTSGP--GTTPSPVPT 2012
Score = 46.2 bits (108), Expect = 5e-04
Identities = 125/576 (21%), Positives = 205/576 (35%), Gaps = 93/576 (16%)
Query: 544 PVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKP---TIPTEKPTI 600
P++ +S+ P++TT T + T T+ S + T + + P T + K T
Sbjct: 1478 PLACSTSSSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTF 1537
Query: 601 STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE 660
ST P P +P+ + ++ T P ++ S KPT++ + +E
Sbjct: 1538 STPSP-------------PPVPATSTSSMST--TTPGT--SVVSSKPTLTEPSTSSCLQE 1580
Query: 661 PTTPTEETTTSMEEPVIP-----------------TEKP-SIPTEKPSIPTEKPTISMEE 702
T TE S P I E P S+ S P ++
Sbjct: 1581 LCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQD 1640
Query: 703 TIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP 762
I S + I K +P P + I + T P + T++ T P
Sbjct: 1641 VICSHTEGLICLNKNQLP---PICYNYEIRIQCCETVNVCRDITRPPK--TVAT---TRP 1692
Query: 763 TEKPTISPEKLTIPTEKPTIPTEKPTIPTEK-PTISTEEPTTPTEETTISTEKP------ 815
T PT + + T T P+ TE+PT + PT ++ T T T +
Sbjct: 1693 TPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNCHPRCTWTKW 1752
Query: 816 ---SIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKL- 871
P P +ET ++ S EK+ +P T P +S E L
Sbjct: 1753 FDVDFPSPGPHGGDKETYNNIIR---SGEKIC---RRPEEITRLQCRAKSHPEVSIEHLG 1806
Query: 872 ----TIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKP 927
E L + P + ++ E + E P P T T P+ P+ +
Sbjct: 1807 QVVQCSREEGLVCRNQDQQGPFK-MCLNYEVRVLCCETPRGCPVTSTPVTA-PSTPSGRA 1864
Query: 928 TIPTEETTI--STEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTI 985
PT+ T+ + T+ T T +P+ T T T ST + PT + T +
Sbjct: 1865 ISPTQSTSSWQKSRTTTLVTTSTTSTPQTST--TYAHTTSTT--SAPTARTT------SA 1914
Query: 986 PTEKPTIPTEKLTALRP---PHPSPTATGLAALVMS---------PHAPSTPMTSVILGT 1033
PT + T + T P P P PT + ++A S AP++ TS +
Sbjct: 1915 PTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSAPTTS 1974
Query: 1034 TTTSRSSTERCPPNARYESCACPASCKSPRPSCGPL 1069
TT++ +S+ P S ++ P + P+
Sbjct: 1975 TTSAPTSSTTSSPQTSTTSAPTTSTTSGPGTTPSPV 2010
Score = 44.7 bits (104), Expect = 0.001
Identities = 62/204 (30%), Positives = 77/204 (37%), Gaps = 40/204 (19%)
Query: 544 PVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTE 603
PV+ T PS +G +PT ST S VTT + P+ T T +T
Sbjct: 1848 PVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYA--HTTSTTS 1905
Query: 604 KPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTIST-EKPTVPTEEPT 662
PT + + P+ + T S P T P PS PT ST PT T +
Sbjct: 1906 APT--ARTTSAPTTRTT--SASPASTTSGPG------NTPSPVPTTSTISAPT--TSITS 1953
Query: 663 TPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTE 722
PT TT S PT S T PT S T T T SP+ T
Sbjct: 1954 APTTSTT-------------SAPT---SSTTSAPTTST--TSAPTSSTTSSPQ-----TS 1990
Query: 723 KPTIPTEKSTISPEKPTTPTEKPT 746
+ PT +T P TTP+ PT
Sbjct: 1991 TTSAPTTSTTSGP--GTTPSPVPT 2012
>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 324 bits (830), Expect = 9e-88
Identities = 298/1197 (24%), Positives = 482/1197 (40%), Gaps = 185/1197 (15%)
Query: 1108 WFSPN------CTEHCRCWPGSRVECQISQCGTHTVCQL----KNGQYGCHPYAGTATCL 1157
+FSP+ C C +CQI Q T CQ+ NG+ G C
Sbjct: 15 FFSPSGSCPYECLNGAFCSKTGTCDCQIFQA-LGTRCQIIPNMGNGRDGI--------CK 65
Query: 1158 VYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGV-SCLSKVYV 1216
+G H+ TFDG ++ F G C+YI A+ CG+ +P + V N + V SC + +
Sbjct: 66 TWGQYHFETFDGIYYYFPGNCSYIFAKDCGD-LEPRYTVWVHNSPKCLGSVYSCYRSISL 124
Query: 1217 TLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLY 1276
+ G G +TLP + +F+ ++ ++T FG + WDG +Y
Sbjct: 125 FFSNQEEIRIYGHEIKKNGISLTLPQTIGQ-IFIEKLADYILVKTTFGFSLAWDGISGIY 183
Query: 1277 VTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVV 1336
+ +S + GK CGLCGNY+ +D + L D NSW +D +C
Sbjct: 184 LKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSD 243
Query: 1337 NSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLC 1396
C S + + + C L+ PF +C ++ + SC+ D+C C
Sbjct: 244 FPNPCSSGMPAFEAIFFKCQILLQF--PFLSCHEYIDPYLYIASCVNDLCKTDD-DETYC 300
Query: 1397 THMSTMTTTCQDAGHAVKPWREPH-FCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR 1455
+ C AG+ ++ WR+ C C + + C CP TC + +
Sbjct: 301 RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLH 360
Query: 1456 CVEACECNPGFVLSGLECIPRSQCGC-LHPAGSYFKVGERWYKPGCKELCVCESNNRIRC 1514
C++ C C G V+ CI C C H G + VG + + C E CVC
Sbjct: 361 CLDGCYCPDGLVMDNGTCISLENCPCGFH--GLAYSVGSK-IEQECTE-CVCVGG----- 411
Query: 1515 QPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWS 1574
W C Q+ C Q C+ GD H+ TFDG + F+G C Y+L +
Sbjct: 412 -VWNCTEQD----------CPVQ----CSVVGDSHFTTFDGRHYSFIGMCQYILVK---G 453
Query: 1575 RSQDSYFVV--SATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWL 1632
+D + + A E G++ + I + F+ ++L RG +++ + ++ +
Sbjct: 454 TGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQG----FN 509
Query: 1633 AQGRVTIR-LSSNLVLLYTNFGLQVRY--DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLD 1689
G V I+ LSS +LL T FGL++ + DG + + + S++ + GLCG +N N D
Sbjct: 510 LNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIY-IQLTSAWKRRTLGLCGTFNGNIRD 568
Query: 1690 DNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP--SSCQENSMADAWNKNCAILIN 1747
D L P + G AW++ + CF P C N + +C ++
Sbjct: 569 DFLSPSGMIEGTPQLHANAWRVSST----CFAPVHVPVVDPCNINQQNIGYAAHCDVI-- 622
Query: 1748 PQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNR-T 1806
Q F+ CH + P + C H C K ++ LC +L YA LC Q G +R + +
Sbjct: 623 HQELFAPCHIYISPGLYYQLCRHDAC--KCGSSCLCNALAHYAYLCGQHGVPIDFRTQIS 680
Query: 1807 FCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS--CVPL 1864
FC + C G Y CSS C +C S+++P C CAE C C +G T CVP+
Sbjct: 681 FCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSD--DCAEGCNCPEGKFYEDTLNFCVPI 738
Query: 1865 GQCGCTDPAGSYHPVGERWYTENTCTRLCTCS---------------------------- 1896
C C Y P GE T + LC CS
Sbjct: 739 FHCRCHYRGSVYQP-GELIPTPSG---LCQCSNGTVKCDELATPSAVHICPEGKEYFDCR 794
Query: 1897 ----------VHNNITC----FQSTCKPNQICWA---------LDGLLRCRASGV-GVCQ 1932
V+ TC TC P+ C + G+ C VC
Sbjct: 795 FPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCT 854
Query: 1933 LPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVY 1992
+ G+ HY SFDG + C + L+K + + A+++K
Sbjct: 855 IYGDRHYYSFDGLEYDYISDCQVFLIKSADDS----DISVIAQNKK-------------- 896
Query: 1993 IDIYDAQVTLQKGHRVLINSKQVTL---PAISQIPGVSVKSSSIYSIVNIKIGVQVKF-- 2047
+D + K + + ++ L P + G +++ S Y + + V F
Sbjct: 897 --CFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTYQLWKAGYYIVVYFPE 954
Query: 2048 -------DGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKD 2100
D + I++ + K+ G+CGNF+ +++ ++ + F +SW
Sbjct: 955 KDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW-- 1012
Query: 2101 KDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLT 2160
C+S DE P E +N A+++C + L + ++A C + ID+T
Sbjct: 1013 --ALGQCES--PDETIKPCEAHQN--------KFPYAKKEC-SILYSDIFASCRNVIDVT 1059
Query: 2161 PFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
F +C C GG + LC ++ A+ C +G+ WR+S+ C L+C Y+
Sbjct: 1060 SFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDCEYYN 1115
Score = 259 bits (663), Expect = 2e-68
Identities = 246/1023 (24%), Positives = 404/1023 (39%), Gaps = 141/1023 (13%)
Query: 1542 CTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKA 1601
C G H+ TFDG ++F G C+Y+ + C V + + G + S ++
Sbjct: 64 CKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVY--SCYRS 121
Query: 1602 VHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGS 1661
+ + + + G ++ NG + LP + G++ I ++ +L+ T FG + +DG
Sbjct: 122 ISLFFSNQEEIRIYGHEIKKNGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGI 179
Query: 1662 HLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFL 1721
+ + + + G+ CGLCGNYN+ DD + D +W + + C L
Sbjct: 180 SGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVL 239
Query: 1722 VGGK-PSSCQENSMA-DAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDT 1779
P+ C A +A C IL+ Q PF CH+ + P ASCV+ C T D
Sbjct: 240 TPSDFPNPCSSGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCVNDLCKTDDDE 297
Query: 1780 TALCRSLQAYASLCAQAGQA-PAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRD 1837
T CR+ YA C+ AG WR+ C +C + C S CP TC+ +
Sbjct: 298 T-YCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTF---EKQ 353
Query: 1838 CPKA-LPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCS 1896
C + L C + C C G ++ +C+ L C C +Y VG + E CT C C
Sbjct: 354 CLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYS-VGSK--IEQECTE-CVC- 408
Query: 1897 VHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLV 1956
V C + C P Q C + G+SH+ +FDG ++S C +
Sbjct: 409 VGGVWNCTEQDC-PVQ------------------CSVVGDSHFTTFDGRHYSFIGMCQYI 449
Query: 1957 LVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYI---DIYDAQVTLQKGHRVLINSK 2013
LVK F I+ + E L + + D ++ QVTL +G ++L +
Sbjct: 450 LVK----GTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPN 505
Query: 2014 Q-VTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF--DGNHLLEIEIPTTYYGKVCGMCG 2070
Q L I +I +S S++ ++ G+++ F DG + I++ + + + G+CG
Sbjct: 506 QGFNLNGIVEIQTLS----SLFILLKTTFGLKILFAIDGERIY-IQLTSAWKRRTLGLCG 560
Query: 2071 NFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCR 2130
FN D+ + PS + + N+W+ + +C + + P + G
Sbjct: 561 TFNGNIRDDFLSPSGMIEGTPQLHANAWR---VSSTCFAPVHVPVVDPCNINQQNIGYAA 617
Query: 2131 AADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGAT 2190
D+ + ++A C I + C + C+ G LC AL +
Sbjct: 618 HCDV----------IHQELFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYL 665
Query: 2191 CQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCIC 2250
C G+ SFC + C Y +C C SC L + CAEGC C
Sbjct: 666 CGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLS---SPEQCSDDCAEGCNC 722
Query: 2251 QPG--YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPS 2308
G Y + + CVP C C + GS+ + + + C C+ G ++C + PS
Sbjct: 723 PEGKFYEDTLNFCVPIFHCRCH--YRGSVYQPGELIPTP-SGLCQCSNGTVKCDELATPS 779
Query: 2309 GSH------------------------CQLTSDN--------SNSNCVS----------- 2325
H C+ T N +S C+S
Sbjct: 780 AVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRR 839
Query: 2326 --------DKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRN 2377
C++YGD Y +FDG Y LIK+ D + V +N
Sbjct: 840 GMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSAD-----DSDISVIAQN 894
Query: 2378 KMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLV 2437
K + + V+ +V ++ L QK + + N+ LW Y+V
Sbjct: 895 KKCFDNDIVCSKSVLISVGDTEIYLND----TPYKQKQSGFFLENKS-TYQLWKAGYYIV 949
Query: 2438 TDF---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFG 2494
F ++ + + + I + ++ +SGLCGN+DK NDM + +N FG
Sbjct: 950 VYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFG 1009
Query: 2495 NSW 2497
+SW
Sbjct: 1010 DSW 1012
Score = 209 bits (532), Expect = 3e-53
Identities = 208/848 (24%), Positives = 327/848 (38%), Gaps = 140/848 (16%)
Query: 1041 TERCPPNARYESC--ACPASCKSPRPSCGPL--CREGCVCNPGFLFSDNHCIQASSCNCF 1096
T++C + + C CP +C + G C +GC C G + + CI +C C
Sbjct: 328 TDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCG 387
Query: 1097 YNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATC 1156
++ Y G++ CTE C G + C C
Sbjct: 388 FHGLAYSVGSK-IEQECTE----------------------CVCVGGVWNCTEQDCPVQC 424
Query: 1157 LVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYV 1216
V GD H+ TFDGRH+ F+G C YIL + G D F K + G+ CL + +
Sbjct: 425 SVVGDSHFTTFDGRHYSFIGMCQYILVK--GTGKDKFTITLQKAPCEQNLGLVCLQSITL 482
Query: 1217 TLPE---STVTLLKGRRTLVGGQQVTLPAIPSKGVFLGA-------SGRFVELQTEFGLR 1266
L + VTL GR GGQ +T P++G L S F+ L+T FGL+
Sbjct: 483 ILEDDFNKQVTL--GR----GGQILT---SPNQGFNLNGIVEIQTLSSLFILLKTTFGLK 533
Query: 1267 VRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQD 1325
+ + D +++Y+ ++S + + GLCG ++GN +D L G G + N+W+
Sbjct: 534 ILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRV--- 590
Query: 1326 EDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLD 1384
C + V+ P D + G+ H F C +++ ++ C D
Sbjct: 591 -SSTC--FAPVHVPVVD-PCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRHD 646
Query: 1385 MCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH 1444
C + LC ++ C G + + FC + C Y C+ C +C
Sbjct: 647 AC--KCGSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCI 704
Query: 1445 SGFSGMFCSDRCVEACECNPG-FVLSGLE-CIPRSQCGCLHPAGSYFKVGERWYKPGCKE 1502
S S CSD C E C C G F L C+P C C H GS ++ GE P
Sbjct: 705 SLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRC-HYRGSVYQPGE--LIPTPSG 761
Query: 1503 LCVCESNNRIRCQPWRC-RAQEFCGQQDGIYGCH-------AQGA------------ATC 1542
LC C SN ++C A C + + C A G TC
Sbjct: 762 LCQC-SNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTC 820
Query: 1543 TAS---------------------------------GDPHYLTFDGALHHFMGTCTYVLT 1569
T S GD HY +FDG + ++ C L
Sbjct: 821 TPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLI 880
Query: 1570 RPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALP 1629
+ + DS V A N+ + ++ K+V ++V D I L ++
Sbjct: 881 K----SADDSDISVIAQNK-KCFDNDIVCSKSVLISVGDTEIYLND------TPYKQKQS 929
Query: 1630 VWLAQGRVTIRL---SSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNN 1686
+ + + T +L +V+ + + + +D + + V + +L GLCGN++
Sbjct: 930 GFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKC 989
Query: 1687 SLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILI 1746
+ +D + ++ G +W L + P + KP +N A K C+IL
Sbjct: 990 TSNDMTTSNNLEVRNARVFGDSWALGQCESPDETI---KPCEAHQNKFPYA-KKECSILY 1045
Query: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRN 1804
+ F+ C V+ S +C C GD LC S+ AYA C Q G + WR+
Sbjct: 1046 S--DIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRS 1103
Query: 1805 RTFCPMRC 1812
T C + C
Sbjct: 1104 STVCSLDC 1111
Score = 175 bits (444), Expect = 5e-43
Identities = 188/844 (22%), Positives = 309/844 (36%), Gaps = 125/844 (14%)
Query: 1929 GVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRL 1988
G+C+ G+ H+ +FDG + P C+ + K C P + + + + G+
Sbjct: 62 GICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLE--PRYTVWVHNSPKCLGSVYSCY 119
Query: 1989 HEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFD 2048
+ + + + GH + N +TLP I + ++ + Y +V G + +D
Sbjct: 120 RSISLFFSNQEEIRIYGHEIKKNGISLTLP--QTIGQIFIEKLADYILVKTTFGFSLAWD 177
Query: 2049 GNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQ 2108
G + +++ + GK CG+CGN+ND + D+ ++ ++ + F NSW + P
Sbjct: 178 GISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQ--TPDDT 235
Query: 2109 SLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN 2168
++ P NP + A KC+ L+ P + C ID ++ C N
Sbjct: 236 KCVLTPSDFP-----NPCSSGMPA-FEAIFFKCQILLQFP-FLSCHEYIDPYLYIASCVN 288
Query: 2169 TLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYSSYTNCLPSCSPS 2227
LC+ + C+A + C G WR+ C +C + +C+ C P+
Sbjct: 289 DLCKTDD-DETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPT 347
Query: 2228 CWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSG 2287
C + +C G+ + C +GC C G V+ C+ C C HG + +G S +
Sbjct: 348 C-TFEKQCLGSNL--HCLDGCYCPDGLVMDNGTCISLENCPC-GFHGLAYSVG-SKIEQE 402
Query: 2288 CTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSY 2347
CTE CVC GG C + CP QCSV GD + TFDG Y
Sbjct: 403 CTE-CVCVGGVWNCTEQDCP---------------------VQCSVVGDSHFTTFDGRHY 440
Query: 2348 RLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTV----YGYKVQLQ 2403
G Y+L+K G + + + + + IT + + +V L
Sbjct: 441 SFIGMCQYILVKGT-----GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLG 495
Query: 2404 AGLELVVNNQKMAVPYRPNEHLRV-------TLWGQRLYLVTDFELVVSFG-GRKNAVIS 2455
G +++ + PN+ + TL + L T F L + F + I
Sbjct: 496 RGGQILTS---------PNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQ 546
Query: 2456 LPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
L S ++ GLCG ++ N ++D + PSG + N+W V + P +P
Sbjct: 547 LTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRV---SSTCFAPVHVPV- 602
Query: 2516 EEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVL 2575
V C+ Q C V+ Q FA CH ++P + + C
Sbjct: 603 ---------------VDPCNINQQNIGYAAHCDVI--HQELFAPCHIYISPGLYYQLCRH 645
Query: 2576 DLCSAQ----------------------DPREQEELRCQVLSGHGVSSRYHISELYDTLP 2613
D C D R Q C V+ G+ + S +
Sbjct: 646 DACKCGSSCLCNALAHYAYLCGQHGVPIDFRTQISF-CAVVCQKGMLYHHCSSFCLHSCI 704
Query: 2614 SI----LCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLT 2669
S+ C G P C+ P+ C C G YQ G T
Sbjct: 705 SLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCV------PIFHCRCHYRGSVYQPGELIPT 758
Query: 2670 EDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGC-FPESPCLQNPCQNDGQCREQGA 2728
S C C++ + E + A +C G C FP+ + C
Sbjct: 759 P--SGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAM 816
Query: 2729 TFTC 2732
FTC
Sbjct: 817 NFTC 820
Score = 86.3 bits (212), Expect = 4e-16
Identities = 99/441 (22%), Positives = 159/441 (36%), Gaps = 58/441 (13%)
Query: 1126 ECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP 1185
+ ++ CG N C + C + + +TFDG + +YIL +
Sbjct: 1411 DVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI 1470
Query: 1186 CGNSTDPFFRVTAKNEE-QGQEGVSCLSKVYVTLPESTVTLLK-GRRTLVGGQQVTLPAI 1243
G + N+ G+ C K+ VT P + + + R+ V V LP
Sbjct: 1471 PGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLP-F 1529
Query: 1244 PSKGVFLGASGRFVELQTEFGLRVRWD---GDQQLYVTVSSTYSGKLCGLCGNYDGNSDN 1300
S+ + + SG + T GL ++W G ++ S GLCG + + D+
Sbjct: 1530 SSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDD 1589
Query: 1301 DHLKLDGSPAGDKEELG---NSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGR 1357
D +G+ + E++G SW+ ++ + ++ V N D C +
Sbjct: 1590 DLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRR-PVRNCTEHD------------CSQ 1636
Query: 1358 LVD--THGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKP 1415
+D F C V F + ++ F + C +S C ++
Sbjct: 1637 CIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ- 1692
Query: 1416 WREPHFCPMACPPNSKYSLCAKPC-PDTC-HSGFSGMFCSDRCVEACECNPGFVL---SG 1470
WR P +C ++CP +Y C +PC TC + F G E C C G VL
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHS 1752
Query: 1471 LECIPRSQCGCLHPAGSYFKVGERW---------YK-----------PGCKE--LCVCES 1508
+CIP +C C GE W YK P C E VCE
Sbjct: 1753 AQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCER 1812
Query: 1509 NNRI---RCQPWRCRAQEFCG 1526
+ W C ++E CG
Sbjct: 1813 EAEVVMGIIDKWTCCSKEVCG 1833
Score = 82.4 bits (202), Expect = 6e-15
Identities = 99/427 (23%), Positives = 162/427 (37%), Gaps = 64/427 (14%)
Query: 1509 NNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVL 1568
N+ I C W C + C+ + +TFDG +Y+L
Sbjct: 1427 NSDICCPEWECPCR-------------------CSMLSELSIITFDGNNAALYSMASYIL 1467
Query: 1569 TRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVAL 1628
R ++ + N+ G + K ++VT I + R + + + +
Sbjct: 1468 VR-IPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLAR-KVEVDSIVV 1525
Query: 1629 PVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVP--------SSYGGQLCGLC 1680
P+ + ++I S ++ ++ T GL +++ SHL + SSY LCG+C
Sbjct: 1526 PLPFSSQELSIEDSGSMYVITTPAGLIIKW--SHLTGIIDIHFGFRFNLSSYTEGLCGIC 1583
Query: 1681 GNYNNNSLDDNLRPDRKLAGDSMQ-LGA---AWKLPESSEPGCFLVGGKP-SSCQENSMA 1735
N DD+LR +M+ +G +W++ +S E + +P +C E+ +
Sbjct: 1584 ----NEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFE----VTMRRPVRNCTEHDCS 1635
Query: 1736 DAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQ 1795
C L+N + F CH V P+ C C +L AY +LC +
Sbjct: 1636 Q-----CIDLLNRR-IFIPCHDKVSPEDF---CEKMWINYTYFWNYECDALSAYVALCNK 1686
Query: 1796 AGQAPAWRNRTFCPMRCPPGSSYSPCSSPC-PDTCSS--INNPRDCPKALPCAESCECQK 1852
WR +C + CP G Y PC PC TC + C L E C C+
Sbjct: 1687 FDICIQWRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC---LNLREDCVCKV 1743
Query: 1853 GHIL---SGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTC- 1908
G +L C+P +C CTD GE W L C + +I + C
Sbjct: 1744 GTVLHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCD 1803
Query: 1909 -KPNQIC 1914
+P +C
Sbjct: 1804 EEPTPVC 1810
Score = 79.3 bits (194), Expect = 5e-14
Identities = 115/557 (20%), Positives = 203/557 (36%), Gaps = 116/557 (20%)
Query: 1818 YSPCSSPCPDTCSSINNPRDCPKALPC-----AESC--ECQKGHILSGTS--------CV 1862
Y PC++PC TCS P+AL C E C C K IL + C+
Sbjct: 1281 YEPCATPCFKTCSD-------PEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCI 1333
Query: 1863 PLGQCGCT--DPAGSYHPVGERW--YTENTCTRLCTCSVHNNITCFQSTCKPNQIC---- 1914
P+ T PA P+ W T + T + + C P C
Sbjct: 1334 PVIPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYI 1393
Query: 1915 ----------WALD-----GLLRCRASGVGV----------------CQLPGESHYVSFD 1943
W+L+ + C G V C + E ++FD
Sbjct: 1394 CLNMEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFD 1453
Query: 1944 GSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQ 2003
G+N ++ + +LV++ + K S ++ G ++ + ++ +
Sbjct: 1454 GNNAALYSMASYILVRIPGEIIVAHIEKCSM-NQAPSGRISGLCFKKLNVTTPIHKIIVN 1512
Query: 2004 K-GHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG-NHLLEIEIP--- 2058
+ +V ++S V LP SQ +S++ S ++ G+ +K+ +++I
Sbjct: 1513 RLARKVEVDSIVVPLPFSSQ--ELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRF 1570
Query: 2059 --TTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSE---FVNSWKDKDIDPSCQSLLVD 2113
++Y +CG+C N++ +D+L M + + + + F+ SW +I+ S + +
Sbjct: 1571 NLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESW---EIEKSFEVTM-- 1622
Query: 2114 EQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEF 2173
P NC D +C L ++ C ++ F C +
Sbjct: 1623 ---------RRPVRNCTEHDC----SQCIDLLNRRIFIPCHDKVSPEDF---CEKMWINY 1666
Query: 2174 GGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSC-SPSCWDLD 2232
+ C AL A+ A C + WR +C L CP Y C+ C + +C L+
Sbjct: 1667 TYFWNYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTC--LN 1723
Query: 2233 GRCEGAKVPSACAEGCICQPGYVLSED---KCVPRSQCGCKDAHGGSIPLGKSWVSSGCT 2289
G E C+C+ G VL +C+P +C C D+ G+ W
Sbjct: 1724 QWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECACTDSEDQPRTAGEIW------ 1777
Query: 2290 EKCVCTGGAIQCGDFRC 2306
GG +C ++C
Sbjct: 1778 -----NGGIDECTLYKC 1789
Score = 69.7 bits (169), Expect = 4e-11
Identities = 93/432 (21%), Positives = 164/432 (37%), Gaps = 80/432 (18%)
Query: 2285 SSGCTEKCV----CTG-GAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRY 2339
S C +C+ C+ G C F+ G+ CQ+ + N + C +G +
Sbjct: 19 SGSCPYECLNGAFCSKTGTCDCQIFQA-LGTRCQIIPNMGNG-----RDGICKTWGQYHF 72
Query: 2340 LTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIF-LQEVITTVYGY 2398
TFDG Y G +Y+ K L EP + S++ I+ +
Sbjct: 73 ETFDGIYYYFPGNCSYIFAKDCGDL----EPRYTVWVHNSPKCLGSVYSCYRSISLFFSN 128
Query: 2399 KVQLQA-GLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLP 2457
+ +++ G E+ N + +P + + + + + T F +++ G + L
Sbjct: 129 QEEIRIYGHEIKKNGISLTLPQTIGQ-IFIEKLADYILVKTTFGFSLAWDGISGIYLKLS 187
Query: 2458 SMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTED--ALLRFPRAIPAE 2515
++G GLCGNY+ + +D ++ T+++ F NSW V+T D + P P
Sbjct: 188 EDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFP-- 245
Query: 2516 EEGQGAELGLRTGLQVSECSPEQLASNST-QACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
+ CS A + C++L Q PF +CH+ + P + CV
Sbjct: 246 ----------------NPCSSGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCV 287
Query: 2575 LDLCSAQDPREQEELRCQVLSGHGVS---SRYHISELYDTLPS--------------ILC 2617
DLC D +E C+ + + + + Y I + D P+ I C
Sbjct: 288 NDLCKTDD----DETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISC 343
Query: 2618 QPGRPRGLRGPLRGRLRQHPRLCLQWHPEP-----------PLADCGCTSNGIYYQLGSS 2666
P + L L CL P L +C C +G+ Y +GS
Sbjct: 344 CPPTCTFEKQCLGSNLH-----CLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSK 398
Query: 2667 FLTEDCSQRCTC 2678
+ ++C++ C C
Sbjct: 399 -IEQECTE-CVC 408
Score = 35.8 bits (81), Expect = 0.61
Identities = 38/191 (19%), Positives = 81/191 (42%), Gaps = 16/191 (8%)
Query: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSI--- 2386
+CS+ + +TFDG + L +Y+L++ +P + +E + P I
Sbjct: 1440 RCSMLSELSIITFDGNNAALYSMASYILVR----IPGEIIVAHIEKCSMNQAPSGRISGL 1495
Query: 2387 -FLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVS 2445
F + +TT + + ++ V++ + +P+ E L + G + T L++
Sbjct: 1496 CFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-LSIEDSGSMYVITTPAGLIIK 1554
Query: 2446 FG---GRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFG---NSWEV 2499
+ G + GLCG +++ +D+ + +G + N+ G SWE+
Sbjct: 1555 WSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEI 1614
Query: 2500 -KTEDALLRFP 2509
K+ + +R P
Sbjct: 1615 EKSFEVTMRRP 1625
>gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 324 bits (830), Expect = 9e-88
Identities = 298/1197 (24%), Positives = 482/1197 (40%), Gaps = 185/1197 (15%)
Query: 1108 WFSPN------CTEHCRCWPGSRVECQISQCGTHTVCQL----KNGQYGCHPYAGTATCL 1157
+FSP+ C C +CQI Q T CQ+ NG+ G C
Sbjct: 15 FFSPSGSCPYECLNGAFCSKTGTCDCQIFQA-LGTRCQIIPNMGNGRDGI--------CK 65
Query: 1158 VYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGV-SCLSKVYV 1216
+G H+ TFDG ++ F G C+YI A+ CG+ +P + V N + V SC + +
Sbjct: 66 TWGQYHFETFDGIYYYFPGNCSYIFAKDCGD-LEPRYTVWVHNSPKCLGSVYSCYRSISL 124
Query: 1217 TLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLY 1276
+ G G +TLP + +F+ ++ ++T FG + WDG +Y
Sbjct: 125 FFSNQEEIRIYGHEIKKNGISLTLPQTIGQ-IFIEKLADYILVKTTFGFSLAWDGISGIY 183
Query: 1277 VTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVV 1336
+ +S + GK CGLCGNY+ +D + L D NSW +D +C
Sbjct: 184 LKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSD 243
Query: 1337 NSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLC 1396
C S + + + C L+ PF +C ++ + SC+ D+C C
Sbjct: 244 FPNPCSSGMPAFEAIFFKCQILLQF--PFLSCHEYIDPYLYIASCVNDLCKTDD-DETYC 300
Query: 1397 THMSTMTTTCQDAGHAVKPWREPH-FCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR 1455
+ C AG+ ++ WR+ C C + + C CP TC + +
Sbjct: 301 RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLH 360
Query: 1456 CVEACECNPGFVLSGLECIPRSQCGC-LHPAGSYFKVGERWYKPGCKELCVCESNNRIRC 1514
C++ C C G V+ CI C C H G + VG + + C E CVC
Sbjct: 361 CLDGCYCPDGLVMDNGTCISLENCPCGFH--GLAYSVGSK-IEQECTE-CVCVGG----- 411
Query: 1515 QPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWS 1574
W C Q+ C Q C+ GD H+ TFDG + F+G C Y+L +
Sbjct: 412 -VWNCTEQD----------CPVQ----CSVVGDSHFTTFDGRHYSFIGMCQYILVK---G 453
Query: 1575 RSQDSYFVV--SATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWL 1632
+D + + A E G++ + I + F+ ++L RG +++ + ++ +
Sbjct: 454 TGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQG----FN 509
Query: 1633 AQGRVTIR-LSSNLVLLYTNFGLQVRY--DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLD 1689
G V I+ LSS +LL T FGL++ + DG + + + S++ + GLCG +N N D
Sbjct: 510 LNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIY-IQLTSAWKRRTLGLCGTFNGNIRD 568
Query: 1690 DNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP--SSCQENSMADAWNKNCAILIN 1747
D L P + G AW++ + CF P C N + +C ++
Sbjct: 569 DFLSPSGMIEGTPQLHANAWRVSST----CFAPVHVPVVDPCNINQQNIGYAAHCDVI-- 622
Query: 1748 PQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNR-T 1806
Q F+ CH + P + C H C K ++ LC +L YA LC Q G +R + +
Sbjct: 623 HQELFAPCHIYISPGLYYQLCRHDAC--KCGSSCLCNALAHYAYLCGQHGVPIDFRTQIS 680
Query: 1807 FCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS--CVPL 1864
FC + C G Y CSS C +C S+++P C CAE C C +G T CVP+
Sbjct: 681 FCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSD--DCAEGCNCPEGKFYEDTLNFCVPI 738
Query: 1865 GQCGCTDPAGSYHPVGERWYTENTCTRLCTCS---------------------------- 1896
C C Y P GE T + LC CS
Sbjct: 739 FHCRCHYRGSVYQP-GELIPTPSG---LCQCSNGTVKCDELATPSAVHICPEGKEYFDCR 794
Query: 1897 ----------VHNNITC----FQSTCKPNQICWA---------LDGLLRCRASGV-GVCQ 1932
V+ TC TC P+ C + G+ C VC
Sbjct: 795 FPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCT 854
Query: 1933 LPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVY 1992
+ G+ HY SFDG + C + L+K + + A+++K
Sbjct: 855 IYGDRHYYSFDGLEYDYISDCQVFLIKSADDS----DISVIAQNKK-------------- 896
Query: 1993 IDIYDAQVTLQKGHRVLINSKQVTL---PAISQIPGVSVKSSSIYSIVNIKIGVQVKF-- 2047
+D + K + + ++ L P + G +++ S Y + + V F
Sbjct: 897 --CFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTYQLWKAGYYIVVYFPE 954
Query: 2048 -------DGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKD 2100
D + I++ + K+ G+CGNF+ +++ ++ + F +SW
Sbjct: 955 KDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW-- 1012
Query: 2101 KDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLT 2160
C+S DE P E +N A+++C + L + ++A C + ID+T
Sbjct: 1013 --ALGQCES--PDETIKPCEAHQN--------KFPYAKKEC-SILYSDIFASCRNVIDVT 1059
Query: 2161 PFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
F +C C GG + LC ++ A+ C +G+ WR+S+ C L+C Y+
Sbjct: 1060 SFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDCEYYN 1115
Score = 259 bits (663), Expect = 2e-68
Identities = 246/1023 (24%), Positives = 404/1023 (39%), Gaps = 141/1023 (13%)
Query: 1542 CTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKA 1601
C G H+ TFDG ++F G C+Y+ + C V + + G + S ++
Sbjct: 64 CKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVY--SCYRS 121
Query: 1602 VHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGS 1661
+ + + + G ++ NG + LP + G++ I ++ +L+ T FG + +DG
Sbjct: 122 ISLFFSNQEEIRIYGHEIKKNGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGI 179
Query: 1662 HLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFL 1721
+ + + + G+ CGLCGNYN+ DD + D +W + + C L
Sbjct: 180 SGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVL 239
Query: 1722 VGGK-PSSCQENSMA-DAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDT 1779
P+ C A +A C IL+ Q PF CH+ + P ASCV+ C T D
Sbjct: 240 TPSDFPNPCSSGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCVNDLCKTDDDE 297
Query: 1780 TALCRSLQAYASLCAQAGQA-PAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRD 1837
T CR+ YA C+ AG WR+ C +C + C S CP TC+ +
Sbjct: 298 T-YCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTF---EKQ 353
Query: 1838 CPKA-LPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCS 1896
C + L C + C C G ++ +C+ L C C +Y VG + E CT C C
Sbjct: 354 CLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYS-VGSK--IEQECTE-CVC- 408
Query: 1897 VHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLV 1956
V C + C P Q C + G+SH+ +FDG ++S C +
Sbjct: 409 VGGVWNCTEQDC-PVQ------------------CSVVGDSHFTTFDGRHYSFIGMCQYI 449
Query: 1957 LVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYI---DIYDAQVTLQKGHRVLINSK 2013
LVK F I+ + E L + + D ++ QVTL +G ++L +
Sbjct: 450 LVK----GTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPN 505
Query: 2014 Q-VTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF--DGNHLLEIEIPTTYYGKVCGMCG 2070
Q L I +I +S S++ ++ G+++ F DG + I++ + + + G+CG
Sbjct: 506 QGFNLNGIVEIQTLS----SLFILLKTTFGLKILFAIDGERIY-IQLTSAWKRRTLGLCG 560
Query: 2071 NFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCR 2130
FN D+ + PS + + N+W+ + +C + + P + G
Sbjct: 561 TFNGNIRDDFLSPSGMIEGTPQLHANAWR---VSSTCFAPVHVPVVDPCNINQQNIGYAA 617
Query: 2131 AADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGAT 2190
D+ + ++A C I + C + C+ G LC AL +
Sbjct: 618 HCDV----------IHQELFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYL 665
Query: 2191 CQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCIC 2250
C G+ SFC + C Y +C C SC L + CAEGC C
Sbjct: 666 CGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLS---SPEQCSDDCAEGCNC 722
Query: 2251 QPG--YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPS 2308
G Y + + CVP C C + GS+ + + + C C+ G ++C + PS
Sbjct: 723 PEGKFYEDTLNFCVPIFHCRCH--YRGSVYQPGELIPTP-SGLCQCSNGTVKCDELATPS 779
Query: 2309 GSH------------------------CQLTSDN--------SNSNCVS----------- 2325
H C+ T N +S C+S
Sbjct: 780 AVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRR 839
Query: 2326 --------DKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRN 2377
C++YGD Y +FDG Y LIK+ D + V +N
Sbjct: 840 GMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSAD-----DSDISVIAQN 894
Query: 2378 KMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLV 2437
K + + V+ +V ++ L QK + + N+ LW Y+V
Sbjct: 895 KKCFDNDIVCSKSVLISVGDTEIYLND----TPYKQKQSGFFLENKS-TYQLWKAGYYIV 949
Query: 2438 TDF---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFG 2494
F ++ + + + I + ++ +SGLCGN+DK NDM + +N FG
Sbjct: 950 VYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFG 1009
Query: 2495 NSW 2497
+SW
Sbjct: 1010 DSW 1012
Score = 209 bits (532), Expect = 3e-53
Identities = 208/848 (24%), Positives = 327/848 (38%), Gaps = 140/848 (16%)
Query: 1041 TERCPPNARYESC--ACPASCKSPRPSCGPL--CREGCVCNPGFLFSDNHCIQASSCNCF 1096
T++C + + C CP +C + G C +GC C G + + CI +C C
Sbjct: 328 TDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCG 387
Query: 1097 YNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATC 1156
++ Y G++ CTE C G + C C
Sbjct: 388 FHGLAYSVGSK-IEQECTE----------------------CVCVGGVWNCTEQDCPVQC 424
Query: 1157 LVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYV 1216
V GD H+ TFDGRH+ F+G C YIL + G D F K + G+ CL + +
Sbjct: 425 SVVGDSHFTTFDGRHYSFIGMCQYILVK--GTGKDKFTITLQKAPCEQNLGLVCLQSITL 482
Query: 1217 TLPE---STVTLLKGRRTLVGGQQVTLPAIPSKGVFLGA-------SGRFVELQTEFGLR 1266
L + VTL GR GGQ +T P++G L S F+ L+T FGL+
Sbjct: 483 ILEDDFNKQVTL--GR----GGQILT---SPNQGFNLNGIVEIQTLSSLFILLKTTFGLK 533
Query: 1267 VRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQD 1325
+ + D +++Y+ ++S + + GLCG ++GN +D L G G + N+W+
Sbjct: 534 ILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRV--- 590
Query: 1326 EDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLD 1384
C + V+ P D + G+ H F C +++ ++ C D
Sbjct: 591 -SSTC--FAPVHVPVVD-PCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRHD 646
Query: 1385 MCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH 1444
C + LC ++ C G + + FC + C Y C+ C +C
Sbjct: 647 AC--KCGSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCI 704
Query: 1445 SGFSGMFCSDRCVEACECNPG-FVLSGLE-CIPRSQCGCLHPAGSYFKVGERWYKPGCKE 1502
S S CSD C E C C G F L C+P C C H GS ++ GE P
Sbjct: 705 SLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRC-HYRGSVYQPGE--LIPTPSG 761
Query: 1503 LCVCESNNRIRCQPWRC-RAQEFCGQQDGIYGCH-------AQGA------------ATC 1542
LC C SN ++C A C + + C A G TC
Sbjct: 762 LCQC-SNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTC 820
Query: 1543 TAS---------------------------------GDPHYLTFDGALHHFMGTCTYVLT 1569
T S GD HY +FDG + ++ C L
Sbjct: 821 TPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLI 880
Query: 1570 RPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALP 1629
+ + DS V A N+ + ++ K+V ++V D I L ++
Sbjct: 881 K----SADDSDISVIAQNK-KCFDNDIVCSKSVLISVGDTEIYLND------TPYKQKQS 929
Query: 1630 VWLAQGRVTIRL---SSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNN 1686
+ + + T +L +V+ + + + +D + + V + +L GLCGN++
Sbjct: 930 GFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKC 989
Query: 1687 SLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILI 1746
+ +D + ++ G +W L + P + KP +N A K C+IL
Sbjct: 990 TSNDMTTSNNLEVRNARVFGDSWALGQCESPDETI---KPCEAHQNKFPYA-KKECSILY 1045
Query: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRN 1804
+ F+ C V+ S +C C GD LC S+ AYA C Q G + WR+
Sbjct: 1046 S--DIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRS 1103
Query: 1805 RTFCPMRC 1812
T C + C
Sbjct: 1104 STVCSLDC 1111
Score = 175 bits (444), Expect = 5e-43
Identities = 188/844 (22%), Positives = 309/844 (36%), Gaps = 125/844 (14%)
Query: 1929 GVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRL 1988
G+C+ G+ H+ +FDG + P C+ + K C P + + + + G+
Sbjct: 62 GICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLE--PRYTVWVHNSPKCLGSVYSCY 119
Query: 1989 HEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFD 2048
+ + + + GH + N +TLP I + ++ + Y +V G + +D
Sbjct: 120 RSISLFFSNQEEIRIYGHEIKKNGISLTLP--QTIGQIFIEKLADYILVKTTFGFSLAWD 177
Query: 2049 GNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQ 2108
G + +++ + GK CG+CGN+ND + D+ ++ ++ + F NSW + P
Sbjct: 178 GISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQ--TPDDT 235
Query: 2109 SLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN 2168
++ P NP + A KC+ L+ P + C ID ++ C N
Sbjct: 236 KCVLTPSDFP-----NPCSSGMPA-FEAIFFKCQILLQFP-FLSCHEYIDPYLYIASCVN 288
Query: 2169 TLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYSSYTNCLPSCSPS 2227
LC+ + C+A + C G WR+ C +C + +C+ C P+
Sbjct: 289 DLCKTDD-DETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPT 347
Query: 2228 CWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSG 2287
C + +C G+ + C +GC C G V+ C+ C C HG + +G S +
Sbjct: 348 C-TFEKQCLGSNL--HCLDGCYCPDGLVMDNGTCISLENCPC-GFHGLAYSVG-SKIEQE 402
Query: 2288 CTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSY 2347
CTE CVC GG C + CP QCSV GD + TFDG Y
Sbjct: 403 CTE-CVCVGGVWNCTEQDCP---------------------VQCSVVGDSHFTTFDGRHY 440
Query: 2348 RLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTV----YGYKVQLQ 2403
G Y+L+K G + + + + + IT + + +V L
Sbjct: 441 SFIGMCQYILVKGT-----GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLG 495
Query: 2404 AGLELVVNNQKMAVPYRPNEHLRV-------TLWGQRLYLVTDFELVVSFG-GRKNAVIS 2455
G +++ + PN+ + TL + L T F L + F + I
Sbjct: 496 RGGQILTS---------PNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQ 546
Query: 2456 LPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
L S ++ GLCG ++ N ++D + PSG + N+W V + P +P
Sbjct: 547 LTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRV---SSTCFAPVHVPV- 602
Query: 2516 EEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVL 2575
V C+ Q C V+ Q FA CH ++P + + C
Sbjct: 603 ---------------VDPCNINQQNIGYAAHCDVI--HQELFAPCHIYISPGLYYQLCRH 645
Query: 2576 DLCSAQ----------------------DPREQEELRCQVLSGHGVSSRYHISELYDTLP 2613
D C D R Q C V+ G+ + S +
Sbjct: 646 DACKCGSSCLCNALAHYAYLCGQHGVPIDFRTQISF-CAVVCQKGMLYHHCSSFCLHSCI 704
Query: 2614 SI----LCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLT 2669
S+ C G P C+ P+ C C G YQ G T
Sbjct: 705 SLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCV------PIFHCRCHYRGSVYQPGELIPT 758
Query: 2670 EDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGC-FPESPCLQNPCQNDGQCREQGA 2728
S C C++ + E + A +C G C FP+ + C
Sbjct: 759 P--SGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAM 816
Query: 2729 TFTC 2732
FTC
Sbjct: 817 NFTC 820
Score = 85.9 bits (211), Expect = 5e-16
Identities = 98/441 (22%), Positives = 159/441 (36%), Gaps = 58/441 (13%)
Query: 1126 ECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP 1185
+ ++ CG N C + C + + +TFDG + +YIL +
Sbjct: 1411 DVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI 1470
Query: 1186 CGNSTDPFFRVTAKNEE-QGQEGVSCLSKVYVTLPESTVTLLK-GRRTLVGGQQVTLPAI 1243
G + N+ G+ C K+ VT P + + + R+ V V LP
Sbjct: 1471 PGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLP-F 1529
Query: 1244 PSKGVFLGASGRFVELQTEFGLRVRWD---GDQQLYVTVSSTYSGKLCGLCGNYDGNSDN 1300
S+ + + SG + T GL ++W G ++ S GLCG + + D+
Sbjct: 1530 SSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDD 1589
Query: 1301 DHLKLDGSPAGDKEELG---NSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGR 1357
D +G+ + E++G SW+ ++ + ++ V N D C +
Sbjct: 1590 DLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRR-PVRNCTEHD------------CSQ 1636
Query: 1358 LVD--THGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKP 1415
+D F C V F + ++ F + C +S C ++
Sbjct: 1637 CIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ- 1692
Query: 1416 WREPHFCPMACPPNSKYSLCAKPC-PDTC-HSGFSGMFCSDRCVEACECNPGFVL---SG 1470
WR P +C ++CP +Y C +PC TC + F G E C C G +L
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHS 1752
Query: 1471 LECIPRSQCGCLHPAGSYFKVGERW---------YK-----------PGCKE--LCVCES 1508
+CIP +C C GE W YK P C E VCE
Sbjct: 1753 AQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCER 1812
Query: 1509 NNRI---RCQPWRCRAQEFCG 1526
+ W C ++E CG
Sbjct: 1813 EAEVVMGIIDKWTCCSKEVCG 1833
Score = 82.8 bits (203), Expect = 4e-15
Identities = 100/427 (23%), Positives = 162/427 (37%), Gaps = 64/427 (14%)
Query: 1509 NNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVL 1568
N+ I C W C + C+ + +TFDG +Y+L
Sbjct: 1427 NSDICCPEWECPCR-------------------CSMLSELSIITFDGNNAALYSMASYIL 1467
Query: 1569 TRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVAL 1628
R ++ + N+ G + K ++VT I + R + + + +
Sbjct: 1468 VR-IPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLAR-KVEVDSIVV 1525
Query: 1629 PVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVP--------SSYGGQLCGLC 1680
P+ + ++I S ++ ++ T GL +++ SHL + SSY LCG+C
Sbjct: 1526 PLPFSSQELSIEDSGSMYVITTPAGLIIKW--SHLTGIIDIHFGFRFNLSSYTEGLCGIC 1583
Query: 1681 GNYNNNSLDDNLRPDRKLAGDSMQ-LGA---AWKLPESSEPGCFLVGGKP-SSCQENSMA 1735
N DD+LR +M+ +G +W++ +S E + +P +C E+ +
Sbjct: 1584 ----NEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFE----VTMRRPVRNCTEHDCS 1635
Query: 1736 DAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQ 1795
C L+N + F CH V P+ C C +L AY +LC +
Sbjct: 1636 Q-----CIDLLNRR-IFIPCHDKVSPEDF---CEKMWINYTYFWNYECDALSAYVALCNK 1686
Query: 1796 AGQAPAWRNRTFCPMRCPPGSSYSPCSSPC-PDTCSS--INNPRDCPKALPCAESCECQK 1852
WR +C + CP G Y PC PC TC + C L E C C+
Sbjct: 1687 FDICIQWRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC---LNLREDCVCKV 1743
Query: 1853 GHIL---SGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTC- 1908
G IL C+P +C CTD GE W L C + +I + C
Sbjct: 1744 GTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCD 1803
Query: 1909 -KPNQIC 1914
+P +C
Sbjct: 1804 EEPTPVC 1810
Score = 79.0 bits (193), Expect = 6e-14
Identities = 114/557 (20%), Positives = 203/557 (36%), Gaps = 116/557 (20%)
Query: 1818 YSPCSSPCPDTCSSINNPRDCPKALPC-----AESC--ECQKGHILSGTS--------CV 1862
Y PC++PC TCS P+AL C E C C K IL + C+
Sbjct: 1281 YEPCATPCFKTCSD-------PEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCI 1333
Query: 1863 PLGQCGCT--DPAGSYHPVGERW--YTENTCTRLCTCSVHNNITCFQSTCKPNQIC---- 1914
P+ T PA P+ W T + T + + C P C
Sbjct: 1334 PVIPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYI 1393
Query: 1915 ----------WALD-----GLLRCRASGVGV----------------CQLPGESHYVSFD 1943
W+L+ + C G V C + E ++FD
Sbjct: 1394 CLNMEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFD 1453
Query: 1944 GSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQ 2003
G+N ++ + +LV++ + K S ++ G ++ + ++ +
Sbjct: 1454 GNNAALYSMASYILVRIPGEIIVAHIEKCSM-NQAPSGRISGLCFKKLNVTTPIHKIIVN 1512
Query: 2004 K-GHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG-NHLLEIEIP--- 2058
+ +V ++S V LP SQ +S++ S ++ G+ +K+ +++I
Sbjct: 1513 RLARKVEVDSIVVPLPFSSQ--ELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRF 1570
Query: 2059 --TTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSE---FVNSWKDKDIDPSCQSLLVD 2113
++Y +CG+C N++ +D+L M + + + + F+ SW +I+ S + +
Sbjct: 1571 NLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESW---EIEKSFEVTM-- 1622
Query: 2114 EQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEF 2173
P NC D +C L ++ C ++ F C +
Sbjct: 1623 ---------RRPVRNCTEHDC----SQCIDLLNRRIFIPCHDKVSPEDF---CEKMWINY 1666
Query: 2174 GGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSC-SPSCWDLD 2232
+ C AL A+ A C + WR +C L CP Y C+ C + +C L+
Sbjct: 1667 TYFWNYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTC--LN 1723
Query: 2233 GRCEGAKVPSACAEGCICQPGYVLSED---KCVPRSQCGCKDAHGGSIPLGKSWVSSGCT 2289
G E C+C+ G +L +C+P +C C D+ G+ W
Sbjct: 1724 QWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIW------ 1777
Query: 2290 EKCVCTGGAIQCGDFRC 2306
GG +C ++C
Sbjct: 1778 -----NGGIDECTLYKC 1789
Score = 69.7 bits (169), Expect = 4e-11
Identities = 93/432 (21%), Positives = 164/432 (37%), Gaps = 80/432 (18%)
Query: 2285 SSGCTEKCV----CTG-GAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRY 2339
S C +C+ C+ G C F+ G+ CQ+ + N + C +G +
Sbjct: 19 SGSCPYECLNGAFCSKTGTCDCQIFQA-LGTRCQIIPNMGNG-----RDGICKTWGQYHF 72
Query: 2340 LTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIF-LQEVITTVYGY 2398
TFDG Y G +Y+ K L EP + S++ I+ +
Sbjct: 73 ETFDGIYYYFPGNCSYIFAKDCGDL----EPRYTVWVHNSPKCLGSVYSCYRSISLFFSN 128
Query: 2399 KVQLQA-GLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLP 2457
+ +++ G E+ N + +P + + + + + T F +++ G + L
Sbjct: 129 QEEIRIYGHEIKKNGISLTLPQTIGQ-IFIEKLADYILVKTTFGFSLAWDGISGIYLKLS 187
Query: 2458 SMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTED--ALLRFPRAIPAE 2515
++G GLCGNY+ + +D ++ T+++ F NSW V+T D + P P
Sbjct: 188 EDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFP-- 245
Query: 2516 EEGQGAELGLRTGLQVSECSPEQLASNST-QACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
+ CS A + C++L Q PF +CH+ + P + CV
Sbjct: 246 ----------------NPCSSGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCV 287
Query: 2575 LDLCSAQDPREQEELRCQVLSGHGVS---SRYHISELYDTLPS--------------ILC 2617
DLC D +E C+ + + + + Y I + D P+ I C
Sbjct: 288 NDLCKTDD----DETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISC 343
Query: 2618 QPGRPRGLRGPLRGRLRQHPRLCLQWHPEP-----------PLADCGCTSNGIYYQLGSS 2666
P + L L CL P L +C C +G+ Y +GS
Sbjct: 344 CPPTCTFEKQCLGSNLH-----CLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSK 398
Query: 2667 FLTEDCSQRCTC 2678
+ ++C++ C C
Sbjct: 399 -IEQECTE-CVC 408
Score = 35.8 bits (81), Expect = 0.61
Identities = 38/191 (19%), Positives = 81/191 (42%), Gaps = 16/191 (8%)
Query: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSI--- 2386
+CS+ + +TFDG + L +Y+L++ +P + +E + P I
Sbjct: 1440 RCSMLSELSIITFDGNNAALYSMASYILVR----IPGEIIVAHIEKCSMNQAPSGRISGL 1495
Query: 2387 -FLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVS 2445
F + +TT + + ++ V++ + +P+ E L + G + T L++
Sbjct: 1496 CFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-LSIEDSGSMYVITTPAGLIIK 1554
Query: 2446 FG---GRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFG---NSWEV 2499
+ G + GLCG +++ +D+ + +G + N+ G SWE+
Sbjct: 1555 WSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEI 1614
Query: 2500 -KTEDALLRFP 2509
K+ + +R P
Sbjct: 1615 EKSFEVTMRRP 1625
Score = 34.7 bits (78), Expect = 1.4
Identities = 26/99 (26%), Positives = 33/99 (33%), Gaps = 22/99 (22%)
Query: 1044 CPPNARYESCACPASCKS-------PRPSCGPLCREGCVCNPGFLFSDNH---CIQASSC 1093
CP Y+ C P ++ SC L RE CVC G + H CI C
Sbjct: 1703 CPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNL-REDCVCKVGTILHRPHSAQCIPEKEC 1761
Query: 1094 NCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQC 1132
C + D E W G EC + +C
Sbjct: 1762 ACTDSEDQPRTAGE-----------IWNGGIDECTLYKC 1789
>gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sapiens]
Length = 2250
Score = 324 bits (830), Expect = 9e-88
Identities = 298/1197 (24%), Positives = 482/1197 (40%), Gaps = 185/1197 (15%)
Query: 1108 WFSPN------CTEHCRCWPGSRVECQISQCGTHTVCQL----KNGQYGCHPYAGTATCL 1157
+FSP+ C C +CQI Q T CQ+ NG+ G C
Sbjct: 15 FFSPSGSCPYECLNGAFCSKTGTCDCQIFQA-LGTRCQIIPNMGNGRDGI--------CK 65
Query: 1158 VYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGV-SCLSKVYV 1216
+G H+ TFDG ++ F G C+YI A+ CG+ +P + V N + V SC + +
Sbjct: 66 TWGQYHFETFDGIYYYFPGNCSYIFAKDCGD-LEPRYTVWVHNSPKCLGSVYSCYRSISL 124
Query: 1217 TLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLY 1276
+ G G +TLP + +F+ ++ ++T FG + WDG +Y
Sbjct: 125 FFSNQEEIRIYGHEIKKNGISLTLPQTIGQ-IFIEKLADYILVKTTFGFSLAWDGISGIY 183
Query: 1277 VTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVV 1336
+ +S + GK CGLCGNY+ +D + L D NSW +D +C
Sbjct: 184 LKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSD 243
Query: 1337 NSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLC 1396
C S + + + C L+ PF +C ++ + SC+ D+C C
Sbjct: 244 FPNPCSSGMPAFEAIFFKCQILLQF--PFLSCHEYIDPYLYIASCVNDLCKTDD-DETYC 300
Query: 1397 THMSTMTTTCQDAGHAVKPWREPH-FCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR 1455
+ C AG+ ++ WR+ C C + + C CP TC + +
Sbjct: 301 RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLH 360
Query: 1456 CVEACECNPGFVLSGLECIPRSQCGC-LHPAGSYFKVGERWYKPGCKELCVCESNNRIRC 1514
C++ C C G V+ CI C C H G + VG + + C E CVC
Sbjct: 361 CLDGCYCPDGLVMDNGTCISLENCPCGFH--GLAYSVGSK-IEQECTE-CVCVGG----- 411
Query: 1515 QPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWS 1574
W C Q+ C Q C+ GD H+ TFDG + F+G C Y+L +
Sbjct: 412 -VWNCTEQD----------CPVQ----CSVVGDSHFTTFDGRHYSFIGMCQYILVK---G 453
Query: 1575 RSQDSYFVV--SATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWL 1632
+D + + A E G++ + I + F+ ++L RG +++ + ++ +
Sbjct: 454 TGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQG----FN 509
Query: 1633 AQGRVTIR-LSSNLVLLYTNFGLQVRY--DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLD 1689
G V I+ LSS +LL T FGL++ + DG + + + S++ + GLCG +N N D
Sbjct: 510 LNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIY-IQLTSAWKRRTLGLCGTFNGNIRD 568
Query: 1690 DNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP--SSCQENSMADAWNKNCAILIN 1747
D L P + G AW++ + CF P C N + +C ++
Sbjct: 569 DFLSPSGMIEGTPQLHANAWRVSST----CFAPVHVPVVDPCNINQQNIGYAAHCDVI-- 622
Query: 1748 PQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNR-T 1806
Q F+ CH + P + C H C K ++ LC +L YA LC Q G +R + +
Sbjct: 623 HQELFAPCHIYISPGLYYQLCRHDAC--KCGSSCLCNALAHYAYLCGQHGVPIDFRTQIS 680
Query: 1807 FCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS--CVPL 1864
FC + C G Y CSS C +C S+++P C CAE C C +G T CVP+
Sbjct: 681 FCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSD--DCAEGCNCPEGKFYEDTLNFCVPI 738
Query: 1865 GQCGCTDPAGSYHPVGERWYTENTCTRLCTCS---------------------------- 1896
C C Y P GE T + LC CS
Sbjct: 739 FHCRCHYRGSVYQP-GELIPTPSG---LCQCSNGTVKCDELATPSAVHICPEGKEYFDCR 794
Query: 1897 ----------VHNNITC----FQSTCKPNQICWA---------LDGLLRCRASGV-GVCQ 1932
V+ TC TC P+ C + G+ C VC
Sbjct: 795 FPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCT 854
Query: 1933 LPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVY 1992
+ G+ HY SFDG + C + L+K + + A+++K
Sbjct: 855 IYGDRHYYSFDGLEYDYISDCQVFLIKSADDS----DISVIAQNKK-------------- 896
Query: 1993 IDIYDAQVTLQKGHRVLINSKQVTL---PAISQIPGVSVKSSSIYSIVNIKIGVQVKF-- 2047
+D + K + + ++ L P + G +++ S Y + + V F
Sbjct: 897 --CFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTYQLWKAGYYIVVYFPE 954
Query: 2048 -------DGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKD 2100
D + I++ + K+ G+CGNF+ +++ ++ + F +SW
Sbjct: 955 KDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW-- 1012
Query: 2101 KDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLT 2160
C+S DE P E +N A+++C + L + ++A C + ID+T
Sbjct: 1013 --ALGQCES--PDETIKPCEAHQN--------KFPYAKKEC-SILYSDIFASCRNVIDVT 1059
Query: 2161 PFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
F +C C GG + LC ++ A+ C +G+ WR+S+ C L+C Y+
Sbjct: 1060 SFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDCEYYN 1115
Score = 259 bits (663), Expect = 2e-68
Identities = 246/1023 (24%), Positives = 404/1023 (39%), Gaps = 141/1023 (13%)
Query: 1542 CTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKA 1601
C G H+ TFDG ++F G C+Y+ + C V + + G + S ++
Sbjct: 64 CKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVY--SCYRS 121
Query: 1602 VHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGS 1661
+ + + + G ++ NG + LP + G++ I ++ +L+ T FG + +DG
Sbjct: 122 ISLFFSNQEEIRIYGHEIKKNGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGI 179
Query: 1662 HLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFL 1721
+ + + + G+ CGLCGNYN+ DD + D +W + + C L
Sbjct: 180 SGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVL 239
Query: 1722 VGGK-PSSCQENSMA-DAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDT 1779
P+ C A +A C IL+ Q PF CH+ + P ASCV+ C T D
Sbjct: 240 TPSDFPNPCSSGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCVNDLCKTDDDE 297
Query: 1780 TALCRSLQAYASLCAQAGQA-PAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRD 1837
T CR+ YA C+ AG WR+ C +C + C S CP TC+ +
Sbjct: 298 T-YCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTF---EKQ 353
Query: 1838 CPKA-LPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCS 1896
C + L C + C C G ++ +C+ L C C +Y VG + E CT C C
Sbjct: 354 CLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYS-VGSK--IEQECTE-CVC- 408
Query: 1897 VHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLV 1956
V C + C P Q C + G+SH+ +FDG ++S C +
Sbjct: 409 VGGVWNCTEQDC-PVQ------------------CSVVGDSHFTTFDGRHYSFIGMCQYI 449
Query: 1957 LVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYI---DIYDAQVTLQKGHRVLINSK 2013
LVK F I+ + E L + + D ++ QVTL +G ++L +
Sbjct: 450 LVK----GTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPN 505
Query: 2014 Q-VTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF--DGNHLLEIEIPTTYYGKVCGMCG 2070
Q L I +I +S S++ ++ G+++ F DG + I++ + + + G+CG
Sbjct: 506 QGFNLNGIVEIQTLS----SLFILLKTTFGLKILFAIDGERIY-IQLTSAWKRRTLGLCG 560
Query: 2071 NFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCR 2130
FN D+ + PS + + N+W+ + +C + + P + G
Sbjct: 561 TFNGNIRDDFLSPSGMIEGTPQLHANAWR---VSSTCFAPVHVPVVDPCNINQQNIGYAA 617
Query: 2131 AADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGAT 2190
D+ + ++A C I + C + C+ G LC AL +
Sbjct: 618 HCDV----------IHQELFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYL 665
Query: 2191 CQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCIC 2250
C G+ SFC + C Y +C C SC L + CAEGC C
Sbjct: 666 CGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLS---SPEQCSDDCAEGCNC 722
Query: 2251 QPG--YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPS 2308
G Y + + CVP C C + GS+ + + + C C+ G ++C + PS
Sbjct: 723 PEGKFYEDTLNFCVPIFHCRCH--YRGSVYQPGELIPTP-SGLCQCSNGTVKCDELATPS 779
Query: 2309 GSH------------------------CQLTSDN--------SNSNCVS----------- 2325
H C+ T N +S C+S
Sbjct: 780 AVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRR 839
Query: 2326 --------DKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRN 2377
C++YGD Y +FDG Y LIK+ D + V +N
Sbjct: 840 GMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSAD-----DSDISVIAQN 894
Query: 2378 KMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLV 2437
K + + V+ +V ++ L QK + + N+ LW Y+V
Sbjct: 895 KKCFDNDIVCSKSVLISVGDTEIYLND----TPYKQKQSGFFLENKS-TYQLWKAGYYIV 949
Query: 2438 TDF---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFG 2494
F ++ + + + I + ++ +SGLCGN+DK NDM + +N FG
Sbjct: 950 VYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFG 1009
Query: 2495 NSW 2497
+SW
Sbjct: 1010 DSW 1012
Score = 209 bits (532), Expect = 3e-53
Identities = 208/848 (24%), Positives = 327/848 (38%), Gaps = 140/848 (16%)
Query: 1041 TERCPPNARYESC--ACPASCKSPRPSCGPL--CREGCVCNPGFLFSDNHCIQASSCNCF 1096
T++C + + C CP +C + G C +GC C G + + CI +C C
Sbjct: 328 TDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCG 387
Query: 1097 YNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATC 1156
++ Y G++ CTE C G + C C
Sbjct: 388 FHGLAYSVGSK-IEQECTE----------------------CVCVGGVWNCTEQDCPVQC 424
Query: 1157 LVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYV 1216
V GD H+ TFDGRH+ F+G C YIL + G D F K + G+ CL + +
Sbjct: 425 SVVGDSHFTTFDGRHYSFIGMCQYILVK--GTGKDKFTITLQKAPCEQNLGLVCLQSITL 482
Query: 1217 TLPE---STVTLLKGRRTLVGGQQVTLPAIPSKGVFLGA-------SGRFVELQTEFGLR 1266
L + VTL GR GGQ +T P++G L S F+ L+T FGL+
Sbjct: 483 ILEDDFNKQVTL--GR----GGQILT---SPNQGFNLNGIVEIQTLSSLFILLKTTFGLK 533
Query: 1267 VRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQD 1325
+ + D +++Y+ ++S + + GLCG ++GN +D L G G + N+W+
Sbjct: 534 ILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRV--- 590
Query: 1326 EDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLD 1384
C + V+ P D + G+ H F C +++ ++ C D
Sbjct: 591 -SSTC--FAPVHVPVVD-PCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRHD 646
Query: 1385 MCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH 1444
C + LC ++ C G + + FC + C Y C+ C +C
Sbjct: 647 AC--KCGSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCI 704
Query: 1445 SGFSGMFCSDRCVEACECNPG-FVLSGLE-CIPRSQCGCLHPAGSYFKVGERWYKPGCKE 1502
S S CSD C E C C G F L C+P C C H GS ++ GE P
Sbjct: 705 SLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRC-HYRGSVYQPGE--LIPTPSG 761
Query: 1503 LCVCESNNRIRCQPWRC-RAQEFCGQQDGIYGCH-------AQGA------------ATC 1542
LC C SN ++C A C + + C A G TC
Sbjct: 762 LCQC-SNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTC 820
Query: 1543 TAS---------------------------------GDPHYLTFDGALHHFMGTCTYVLT 1569
T S GD HY +FDG + ++ C L
Sbjct: 821 TPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLI 880
Query: 1570 RPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALP 1629
+ + DS V A N+ + ++ K+V ++V D I L ++
Sbjct: 881 K----SADDSDISVIAQNK-KCFDNDIVCSKSVLISVGDTEIYLND------TPYKQKQS 929
Query: 1630 VWLAQGRVTIRL---SSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNN 1686
+ + + T +L +V+ + + + +D + + V + +L GLCGN++
Sbjct: 930 GFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKC 989
Query: 1687 SLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILI 1746
+ +D + ++ G +W L + P + KP +N A K C+IL
Sbjct: 990 TSNDMTTSNNLEVRNARVFGDSWALGQCESPDETI---KPCEAHQNKFPYA-KKECSILY 1045
Query: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRN 1804
+ F+ C V+ S +C C GD LC S+ AYA C Q G + WR+
Sbjct: 1046 S--DIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRS 1103
Query: 1805 RTFCPMRC 1812
T C + C
Sbjct: 1104 STVCSLDC 1111
Score = 175 bits (444), Expect = 5e-43
Identities = 188/844 (22%), Positives = 309/844 (36%), Gaps = 125/844 (14%)
Query: 1929 GVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRL 1988
G+C+ G+ H+ +FDG + P C+ + K C P + + + + G+
Sbjct: 62 GICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLE--PRYTVWVHNSPKCLGSVYSCY 119
Query: 1989 HEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFD 2048
+ + + + GH + N +TLP I + ++ + Y +V G + +D
Sbjct: 120 RSISLFFSNQEEIRIYGHEIKKNGISLTLP--QTIGQIFIEKLADYILVKTTFGFSLAWD 177
Query: 2049 GNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQ 2108
G + +++ + GK CG+CGN+ND + D+ ++ ++ + F NSW + P
Sbjct: 178 GISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQ--TPDDT 235
Query: 2109 SLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN 2168
++ P NP + A KC+ L+ P + C ID ++ C N
Sbjct: 236 KCVLTPSDFP-----NPCSSGMPA-FEAIFFKCQILLQFP-FLSCHEYIDPYLYIASCVN 288
Query: 2169 TLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYSSYTNCLPSCSPS 2227
LC+ + C+A + C G WR+ C +C + +C+ C P+
Sbjct: 289 DLCKTDD-DETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPT 347
Query: 2228 CWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSG 2287
C + +C G+ + C +GC C G V+ C+ C C HG + +G S +
Sbjct: 348 C-TFEKQCLGSNL--HCLDGCYCPDGLVMDNGTCISLENCPC-GFHGLAYSVG-SKIEQE 402
Query: 2288 CTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSY 2347
CTE CVC GG C + CP QCSV GD + TFDG Y
Sbjct: 403 CTE-CVCVGGVWNCTEQDCP---------------------VQCSVVGDSHFTTFDGRHY 440
Query: 2348 RLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTV----YGYKVQLQ 2403
G Y+L+K G + + + + + IT + + +V L
Sbjct: 441 SFIGMCQYILVKGT-----GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLG 495
Query: 2404 AGLELVVNNQKMAVPYRPNEHLRV-------TLWGQRLYLVTDFELVVSFG-GRKNAVIS 2455
G +++ + PN+ + TL + L T F L + F + I
Sbjct: 496 RGGQILTS---------PNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQ 546
Query: 2456 LPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
L S ++ GLCG ++ N ++D + PSG + N+W V + P +P
Sbjct: 547 LTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRV---SSTCFAPVHVPV- 602
Query: 2516 EEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVL 2575
V C+ Q C V+ Q FA CH ++P + + C
Sbjct: 603 ---------------VDPCNINQQNIGYAAHCDVI--HQELFAPCHIYISPGLYYQLCRH 645
Query: 2576 DLCSAQ----------------------DPREQEELRCQVLSGHGVSSRYHISELYDTLP 2613
D C D R Q C V+ G+ + S +
Sbjct: 646 DACKCGSSCLCNALAHYAYLCGQHGVPIDFRTQISF-CAVVCQKGMLYHHCSSFCLHSCI 704
Query: 2614 SI----LCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLT 2669
S+ C G P C+ P+ C C G YQ G T
Sbjct: 705 SLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCV------PIFHCRCHYRGSVYQPGELIPT 758
Query: 2670 EDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGC-FPESPCLQNPCQNDGQCREQGA 2728
S C C++ + E + A +C G C FP+ + C
Sbjct: 759 P--SGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAM 816
Query: 2729 TFTC 2732
FTC
Sbjct: 817 NFTC 820
Score = 85.9 bits (211), Expect = 5e-16
Identities = 98/441 (22%), Positives = 159/441 (36%), Gaps = 58/441 (13%)
Query: 1126 ECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP 1185
+ ++ CG N C + C + + +TFDG + +YIL +
Sbjct: 1411 DVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI 1470
Query: 1186 CGNSTDPFFRVTAKNEE-QGQEGVSCLSKVYVTLPESTVTLLK-GRRTLVGGQQVTLPAI 1243
G + N+ G+ C K+ VT P + + + R+ V V LP
Sbjct: 1471 PGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLP-F 1529
Query: 1244 PSKGVFLGASGRFVELQTEFGLRVRWD---GDQQLYVTVSSTYSGKLCGLCGNYDGNSDN 1300
S+ + + SG + T GL ++W G ++ S GLCG + + D+
Sbjct: 1530 SSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDD 1589
Query: 1301 DHLKLDGSPAGDKEELG---NSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGR 1357
D +G+ + E++G SW+ ++ + ++ V N D C +
Sbjct: 1590 DLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRR-PVRNCTEHD------------CSQ 1636
Query: 1358 LVD--THGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKP 1415
+D F C V F + ++ F + C +S C ++
Sbjct: 1637 CIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ- 1692
Query: 1416 WREPHFCPMACPPNSKYSLCAKPC-PDTC-HSGFSGMFCSDRCVEACECNPGFVL---SG 1470
WR P +C ++CP +Y C +PC TC + F G E C C G +L
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHS 1752
Query: 1471 LECIPRSQCGCLHPAGSYFKVGERW---------YK-----------PGCKE--LCVCES 1508
+CIP +C C GE W YK P C E VCE
Sbjct: 1753 AQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCER 1812
Query: 1509 NNRI---RCQPWRCRAQEFCG 1526
+ W C ++E CG
Sbjct: 1813 EAEVVMGIIDKWTCCSKEVCG 1833
Score = 82.8 bits (203), Expect = 4e-15
Identities = 100/427 (23%), Positives = 162/427 (37%), Gaps = 64/427 (14%)
Query: 1509 NNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVL 1568
N+ I C W C + C+ + +TFDG +Y+L
Sbjct: 1427 NSDICCPEWECPCR-------------------CSMLSELSIITFDGNNAALYSMASYIL 1467
Query: 1569 TRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVAL 1628
R ++ + N+ G + K ++VT I + R + + + +
Sbjct: 1468 VR-IPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLAR-KVEVDSIVV 1525
Query: 1629 PVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVP--------SSYGGQLCGLC 1680
P+ + ++I S ++ ++ T GL +++ SHL + SSY LCG+C
Sbjct: 1526 PLPFSSQELSIEDSGSMYVITTPAGLIIKW--SHLTGIIDIHFGFRFNLSSYTEGLCGIC 1583
Query: 1681 GNYNNNSLDDNLRPDRKLAGDSMQ-LGA---AWKLPESSEPGCFLVGGKP-SSCQENSMA 1735
N DD+LR +M+ +G +W++ +S E + +P +C E+ +
Sbjct: 1584 ----NEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFE----VTMRRPVRNCTEHDCS 1635
Query: 1736 DAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQ 1795
C L+N + F CH V P+ C C +L AY +LC +
Sbjct: 1636 Q-----CIDLLNRR-IFIPCHDKVSPEDF---CEKMWINYTYFWNYECDALSAYVALCNK 1686
Query: 1796 AGQAPAWRNRTFCPMRCPPGSSYSPCSSPC-PDTCSS--INNPRDCPKALPCAESCECQK 1852
WR +C + CP G Y PC PC TC + C L E C C+
Sbjct: 1687 FDICIQWRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSC---LNLREDCVCKV 1743
Query: 1853 GHIL---SGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTC- 1908
G IL C+P +C CTD GE W L C + +I + C
Sbjct: 1744 GTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCD 1803
Query: 1909 -KPNQIC 1914
+P +C
Sbjct: 1804 EEPTPVC 1810
Score = 79.0 bits (193), Expect = 6e-14
Identities = 114/557 (20%), Positives = 203/557 (36%), Gaps = 116/557 (20%)
Query: 1818 YSPCSSPCPDTCSSINNPRDCPKALPC-----AESC--ECQKGHILSGTS--------CV 1862
Y PC++PC TCS P+AL C E C C K IL + C+
Sbjct: 1281 YEPCATPCFKTCSD-------PEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCI 1333
Query: 1863 PLGQCGCT--DPAGSYHPVGERW--YTENTCTRLCTCSVHNNITCFQSTCKPNQIC---- 1914
P+ T PA P+ W T + T + + C P C
Sbjct: 1334 PVIPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYI 1393
Query: 1915 ----------WALD-----GLLRCRASGVGV----------------CQLPGESHYVSFD 1943
W+L+ + C G V C + E ++FD
Sbjct: 1394 CLNMEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFD 1453
Query: 1944 GSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQ 2003
G+N ++ + +LV++ + K S ++ G ++ + ++ +
Sbjct: 1454 GNNAALYSMASYILVRIPGEIIVAHIEKCSM-NQAPSGRISGLCFKKLNVTTPIHKIIVN 1512
Query: 2004 K-GHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG-NHLLEIEIP--- 2058
+ +V ++S V LP SQ +S++ S ++ G+ +K+ +++I
Sbjct: 1513 RLARKVEVDSIVVPLPFSSQ--ELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRF 1570
Query: 2059 --TTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSE---FVNSWKDKDIDPSCQSLLVD 2113
++Y +CG+C N++ +D+L M + + + + F+ SW +I+ S + +
Sbjct: 1571 NLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESW---EIEKSFEVTM-- 1622
Query: 2114 EQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEF 2173
P NC D +C L ++ C ++ F C +
Sbjct: 1623 ---------RRPVRNCTEHDC----SQCIDLLNRRIFIPCHDKVSPEDF---CEKMWINY 1666
Query: 2174 GGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSC-SPSCWDLD 2232
+ C AL A+ A C + WR +C L CP Y C+ C + +C L+
Sbjct: 1667 TYFWNYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTC--LN 1723
Query: 2233 GRCEGAKVPSACAEGCICQPGYVLSED---KCVPRSQCGCKDAHGGSIPLGKSWVSSGCT 2289
G E C+C+ G +L +C+P +C C D+ G+ W
Sbjct: 1724 QWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIW------ 1777
Query: 2290 EKCVCTGGAIQCGDFRC 2306
GG +C ++C
Sbjct: 1778 -----NGGIDECTLYKC 1789
Score = 69.7 bits (169), Expect = 4e-11
Identities = 93/432 (21%), Positives = 164/432 (37%), Gaps = 80/432 (18%)
Query: 2285 SSGCTEKCV----CTG-GAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRY 2339
S C +C+ C+ G C F+ G+ CQ+ + N + C +G +
Sbjct: 19 SGSCPYECLNGAFCSKTGTCDCQIFQA-LGTRCQIIPNMGNG-----RDGICKTWGQYHF 72
Query: 2340 LTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIF-LQEVITTVYGY 2398
TFDG Y G +Y+ K L EP + S++ I+ +
Sbjct: 73 ETFDGIYYYFPGNCSYIFAKDCGDL----EPRYTVWVHNSPKCLGSVYSCYRSISLFFSN 128
Query: 2399 KVQLQA-GLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLP 2457
+ +++ G E+ N + +P + + + + + T F +++ G + L
Sbjct: 129 QEEIRIYGHEIKKNGISLTLPQTIGQ-IFIEKLADYILVKTTFGFSLAWDGISGIYLKLS 187
Query: 2458 SMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTED--ALLRFPRAIPAE 2515
++G GLCGNY+ + +D ++ T+++ F NSW V+T D + P P
Sbjct: 188 EDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFP-- 245
Query: 2516 EEGQGAELGLRTGLQVSECSPEQLASNST-QACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
+ CS A + C++L Q PF +CH+ + P + CV
Sbjct: 246 ----------------NPCSSGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCV 287
Query: 2575 LDLCSAQDPREQEELRCQVLSGHGVS---SRYHISELYDTLPS--------------ILC 2617
DLC D +E C+ + + + + Y I + D P+ I C
Sbjct: 288 NDLCKTDD----DETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISC 343
Query: 2618 QPGRPRGLRGPLRGRLRQHPRLCLQWHPEP-----------PLADCGCTSNGIYYQLGSS 2666
P + L L CL P L +C C +G+ Y +GS
Sbjct: 344 CPPTCTFEKQCLGSNLH-----CLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSK 398
Query: 2667 FLTEDCSQRCTC 2678
+ ++C++ C C
Sbjct: 399 -IEQECTE-CVC 408
Score = 35.8 bits (81), Expect = 0.61
Identities = 38/191 (19%), Positives = 81/191 (42%), Gaps = 16/191 (8%)
Query: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSI--- 2386
+CS+ + +TFDG + L +Y+L++ +P + +E + P I
Sbjct: 1440 RCSMLSELSIITFDGNNAALYSMASYILVR----IPGEIIVAHIEKCSMNQAPSGRISGL 1495
Query: 2387 -FLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVS 2445
F + +TT + + ++ V++ + +P+ E L + G + T L++
Sbjct: 1496 CFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-LSIEDSGSMYVITTPAGLIIK 1554
Query: 2446 FG---GRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFG---NSWEV 2499
+ G + GLCG +++ +D+ + +G + N+ G SWE+
Sbjct: 1555 WSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEI 1614
Query: 2500 -KTEDALLRFP 2509
K+ + +R P
Sbjct: 1615 EKSFEVTMRRP 1625
Score = 34.7 bits (78), Expect = 1.4
Identities = 26/99 (26%), Positives = 33/99 (33%), Gaps = 22/99 (22%)
Query: 1044 CPPNARYESCACPASCKS-------PRPSCGPLCREGCVCNPGFLFSDNH---CIQASSC 1093
CP Y+ C P ++ SC L RE CVC G + H CI C
Sbjct: 1703 CPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNL-REDCVCKVGTILHRPHSAQCIPEKEC 1761
Query: 1094 NCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQC 1132
C + D E W G EC + +C
Sbjct: 1762 ACTDSEDQPRTAGE-----------IWNGGIDECTLYKC 1789
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 298 bits (762), Expect = 7e-80
Identities = 315/1277 (24%), Positives = 487/1277 (38%), Gaps = 222/1277 (17%)
Query: 1152 GTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCL 1211
G C +G+ HY TFDG F F G C Y A C S F V K E + +
Sbjct: 33 GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEF-AVHLKRGPGQAEAPAGV 91
Query: 1212 SKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDG 1271
+ +T+ + T+ L + ++ G V+ P S G+ + S + ++ + GL + W+
Sbjct: 92 ESILLTIKDDTIYLTR-HLAVLNGAVVSTPHY-SPGLLIEKSDAYTKVYSRAGLTLMWNR 149
Query: 1272 DQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDG---SPAGDKEELGNSWQTDQDEDQ 1328
+ L + + + + CGLCG+Y+G DG SP E GN + +Q D
Sbjct: 150 EDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL----EFGNMQKINQP-DV 204
Query: 1329 ECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGF 1388
C+ + +P+ S ++ C RL+ T F C V + +C D C
Sbjct: 205 VCEDPEEEVAPASCSEHRAE------CERLL-TAEAFADCQDLVPLEPYLRACQQDRCRC 257
Query: 1389 QGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFS 1448
G +C+ ++ + C AG WR CP CP N Y PC DTC
Sbjct: 258 PGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLEV 317
Query: 1449 GMFCSDRCVEACECNPGFVLSGLE---CIPRSQCGCLHPAGSYFKVGERWYKPGCK---- 1501
C + ++ C C G V + C+P SQC C ++ Y PG +
Sbjct: 318 SSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHC--------RLHGHLYTPGQEITND 369
Query: 1502 -ELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHF 1560
E CVC + W C+ G TC G H TFDG + F
Sbjct: 370 CEQCVCNAGR------WVCKDLPCPG--------------TCALEGGSHITTFDGKTYTF 409
Query: 1561 MGTCTYVLTRPCWSRSQDSYFVVS-----ATNENRGGILEVSYI--KAVHVTVFDLSISL 1613
G C YVL + DSY ++ + + + + V + K +V VF S
Sbjct: 410 HGDCYYVLAK---GDHNDSYALLGELAPCGSTDKQTCLKTVVLLADKKKNVVVFKSDGS- 465
Query: 1614 LRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVE--VTVPSS 1671
V+LN +V LP A V R SS +++ G++++ + +++ VT+ +
Sbjct: 466 -----VLLNELQVNLPHVTASFSV-FRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQA 519
Query: 1672 YGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPS-SCQ 1730
GQ+ GLCGN+N DD + WK S + S + +
Sbjct: 520 SQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIE 579
Query: 1731 ENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYA 1790
+ A+ W C++L + PF +CH V P + C + C + + LC +L +YA
Sbjct: 580 SANYAEHW---CSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYA 636
Query: 1791 SLCAQAG-QAPAWRNRTFCPM---RCPPGSSYSPCSSPCPDTCSSINN----------PR 1836
C G WR C CP + + C TC S++ P
Sbjct: 637 RACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPV 695
Query: 1837 D---CP---------KALPCA---------------------ESCECQKGHI------LS 1857
D CP + +P A E C C+ G + L
Sbjct: 696 DGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLI 755
Query: 1858 GTSCV-PLGQCGCTD-----------------PAGSYH---------PVGERWYTENTCT 1890
G SC P C++ AG YH P G C
Sbjct: 756 GQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCV 815
Query: 1891 --RLCTCSVHNN----------ITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESH 1938
+ C C VHNN + C TCK + W +A G C + G H
Sbjct: 816 VEKECPC-VHNNDLYSSGAKIKVDCNTCTCKRGR--WVCT-----QAVCHGTCSIYGSGH 867
Query: 1939 YVSFDGSNHSIPDACTLVLVK-VCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYD 1997
Y++FDG + C+ V V+ C +L F I ++ G T + I +
Sbjct: 868 YITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPC-GTTGVTCSKAIKIFMGR 926
Query: 1998 AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEI 2057
++ L+ HRV+I + + + Y +V G+ V +D + I++
Sbjct: 927 TELKLEDKHRVVIQRDE------GHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKL 980
Query: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQI 2117
+Y G VCG+CGNF+ ++ V +S+ +F NSWK+ P+C +
Sbjct: 981 APSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---PTCPDV------- 1030
Query: 2118 PAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCA--NTLCEFGG 2175
NP R EK + L++ V++ C S++D PF C + C+ GG
Sbjct: 1031 ----STNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGG 1086
Query: 2176 LYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS-------SYTNCLPSCSPSC 2228
+ C A+ ++ C +G WR CP+ C Y+ Y C +C
Sbjct: 1087 DCECFCSAVASYAQECTKEG-ACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETC 1145
Query: 2229 WDLDGRCEGAKVPSACAEGCI--C---QPGYVLSEDKCVPRSQCGC--KDAHGGSIPLGK 2281
++G V + EGC C +P Y KCV +CGC +D H P G
Sbjct: 1146 RTINGIHSNISV--SYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTH---YPPGA 1200
Query: 2282 SWVSSGCTEKCVCTGGA 2298
S + + CVCT +
Sbjct: 1201 SVPTEETCKSCVCTNSS 1217
Score = 245 bits (626), Expect = 4e-64
Identities = 297/1250 (23%), Positives = 465/1250 (37%), Gaps = 226/1250 (18%)
Query: 1538 GAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEV- 1596
G C+ G+ HY TFDG + F G C Y C + SY + + G E
Sbjct: 33 GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC----RGSYKEFAVHLKRGPGQAEAP 88
Query: 1597 SYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQV 1656
+ ++++ +T+ D +I L R V LNG V+ P + + I S +Y+ GL +
Sbjct: 89 AGVESILLTIKDDTIYLTRHLAV-LNGAVVSTPHY--SPGLLIEKSDAYTKVYSRAGLTL 145
Query: 1657 RYDGSHLVEVTVPSSYGGQLCGLCGNYN-----NNSLDDNLRPDRKLAGDSMQLGAAWKL 1711
++ + + + + + CGLCG+YN + L D + G+ ++ +
Sbjct: 146 MWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVV 205
Query: 1712 PESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHG 1771
E E P+SC E+ C L+ + F+ C +VP + +C
Sbjct: 206 CEDPEEEV-----APASCSEH------RAECERLLTAEA-FADCQDLVPLEPYLRACQQD 253
Query: 1772 QCGTKGDTTALCRSLQAYASLCAQAGQAPA-WRNRTFCPMRCPPGSSYSPCSSPCPDTCS 1830
+C G T +C ++ ++ C+ AG P WR T CP CP Y SPC DTCS
Sbjct: 254 RCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCS 313
Query: 1831 SINNPRDCPKALPCAESCECQKGHI---LSGTSCVPLGQCGCTDPAGSYHPVGERWYTEN 1887
+ C + + C C +G + + + CVP+ QC C Y P E N
Sbjct: 314 HLEVSSLCEEHR--MDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQE---ITN 368
Query: 1888 TCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNH 1947
C + C C+ + CK L C G C L G SH +FDG +
Sbjct: 369 DCEQ-CVCNAGRWV------CKD----------LPCP----GTCALEGGSHITTFDGKTY 407
Query: 1948 SIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQ---VTLQK 2004
+ C VL K H +++ G T+ + + + D + V +
Sbjct: 408 TFHGDCYYVLAKGDHNDSYALLGELAPC-----GSTDKQTCLKTVVLLADKKKNVVVFKS 462
Query: 2005 GHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGV--QVKFDGNHLLEIEIPTTYY 2062
VL+N QV LP ++ V + SS + +V++ IGV QV+ L + +
Sbjct: 463 DGSVLLNELQVNLPHVTASFSV-FRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQ 521
Query: 2063 GKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQ 2122
G+V G+CGNFN E D+ S V + + F N+WK + SC L +
Sbjct: 522 GQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS---SCHDKL--------DWL 570
Query: 2123 ENP-SGNCRAADLRRAREKCEAALRAPV-WAQCASRIDLTPFLVDCANTLCEFGGLYQAL 2180
++P S N +A+ A C + + +C S +D + C C L
Sbjct: 571 DDPCSLNIESANY--AEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCL 628
Query: 2181 CQALQAFGATCQSQGLKPPLWRNSSFCPLE---CPAYSSYTNCLPSCSPSCWDL---DGR 2234
C AL ++ C ++G+ WR C + CP + L +C +C L D
Sbjct: 629 CAALSSYARACTAKGVMLWGWREH-VCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSH 687
Query: 2235 CEGAKVPSACAEGCICQPGYVLSED-KCVP----------------------RSQCGCKD 2271
C P +GC C L E +CVP +C C+D
Sbjct: 688 CLEGFAP---VDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRD 744
Query: 2272 ----------------------------AHGGSIP-------LGKSWVSSGCTEKCVCTG 2296
A S P L + + C CVC
Sbjct: 745 GRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPD 804
Query: 2297 GAIQCGDFRCPSGSHCQLTSDNSN-----------SNCVSDKSE----------QCSVYG 2335
G + G C C +N + C + CS+YG
Sbjct: 805 GLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYG 864
Query: 2336 DPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTV 2395
Y+TFDG Y G +YV ++ + + N + + + + I
Sbjct: 865 SGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITEN-VPCGTTGVTCSKAIKIF 923
Query: 2396 YGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLW--GQRLYLVTDFELVVSFGGRKNAV 2453
G + + LE + ++ + H+ T GQ L + + ++V + R
Sbjct: 924 MG---RTELKLE---DKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVF 977
Query: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513
I L Y+G V GLCGN+D ND + + FGNSW + P
Sbjct: 978 IKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSW------------KEAP 1025
Query: 2514 AEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHC 2573
+ + T + +P + S + + C +L F+ CH V P+PF E C
Sbjct: 1026 TCPD-------VSTNPEPCSLNPHR-RSWAEKQCSIL--KSSVFSICHSKVDPKPFYEAC 1075
Query: 2574 VLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRPRGLRGPLRGRL 2633
V D CS D E C ++ + + ++ P LC P+
Sbjct: 1076 VHDSCSC-DTGGDCECFCSAVASYAQECTKEGACVFWRTPD-LC----------PIFCDY 1123
Query: 2634 RQHPRLCLQWHPEPPLADCG------C-TSNGIYYQLGSSFLTEDCSQRC 2676
P C +WH EP CG C T NGI+ + S+L E C RC
Sbjct: 1124 YNPPHEC-EWHYEP----CGNRSFETCRTINGIHSNISVSYL-EGCYPRC 1167
Score = 216 bits (549), Expect = 3e-55
Identities = 300/1138 (26%), Positives = 420/1138 (36%), Gaps = 104/1138 (9%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3774 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3830
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3831 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3890
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3891 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3949
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3950 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 4006
Query: 705 ISTEKPTISPEKPTI---PTEKPTIPTEKSTISPEKPTT---PTEKPTIPTEKPTISPEK 758
T+ PT +P T PT PT T+ T +P TT PT PT T+ PT +P
Sbjct: 4007 TGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPIT 4064
Query: 759 PTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-I 817
TT T PT +P PT P I T PT PT + TTP TT T P+
Sbjct: 4065 TTT-TVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4122
Query: 818 PMEKPTLPTEETTTSVEETTIST---EKLTIPMEKPTISTEKPT-IPTEKPTISPEKLTI 873
+ PT TTT+V T T T P+ T T PT T+ PT +P T
Sbjct: 4123 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4182
Query: 874 -------PTEKLT-IPTEKPTIPIEETTIST---EKLTIPTEKPTISP--EKPTI-STEK 919
PT T PT T PI E T S E T T + T SP E T+ ST
Sbjct: 4183 TVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLP 4242
Query: 920 PTIP---TEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTI-STEKPTIPTEK 975
P I T P+ PT TT S P T SP PT T S+ PT T +
Sbjct: 4243 PAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGT--PTRGTTTGSSSAPTPSTVQ 4300
Query: 976 LTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTT 1035
T + PT T + T LRP +PS L + +AP + + G T
Sbjct: 4301 TTTTSAWTPTPTPLSTPSIIRTTGLRP-YPSSVLI-CCVLNDTYYAPGEEVYNGTYGDTC 4358
Query: 1036 TSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGFLFSD-NHCIQASSCN 1094
+ + C + + +CP++ P P+ P P S + C
Sbjct: 4359 YFVNCSLSC--TLEFYNWSCPST---PSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECP 4413
Query: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYG-------- 1146
F + + W+ +C C + VE +C + NG
Sbjct: 4414 DF--DPPRQENETWWLCDCFM-ATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDG 4470
Query: 1147 -CHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQ 1205
C + C +GDPHYVTFDG ++ + G CTY+L + S D F
Sbjct: 4471 CCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPN 4530
Query: 1206 EGVSCLSKVYVTLPESTVTLLKGRRTL-------VGGQQVTLPAIPSKGVFLGASG-RFV 1257
+ VSC + + E+ L+K + V Q V LP G+ + SG +V
Sbjct: 4531 DKVSC-PRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALP-YKKYGLEVYQSGINYV 4588
Query: 1258 ELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELG 1317
E G+ V ++G + G CG + +D + G + E
Sbjct: 4589 VDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAA 4648
Query: 1318 NSWQTDQDEDQEC------QKYQVVNSPSCDSSLQSSMSGPG-FCGRLVDTHGPFETCLL 1370
+ W + C K V P + P C + D+ F C
Sbjct: 4649 DQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDS--LFAQCHA 4706
Query: 1371 HVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPH-FCPMACPPN 1429
V ++D+C+ D C G L C + C + H C + CP +
Sbjct: 4707 LVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSH 4765
Query: 1430 SKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFV--LSGLECIPRSQCGCLHPAGS 1487
+Y C TC S S + VE C C G + G + ++ CGC+ P
Sbjct: 4766 REYQACGPAEEPTCKSS-SSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT-CGCVGPDNV 4823
Query: 1488 YFKVGERWYKPGCKELCVC-ESNNRIRCQPWRCRAQEFCG-QQDGIY-GCHAQGAATC 1542
+ GE ++ CK CVC E + I CQP RC + +DG Y A TC
Sbjct: 4824 PREFGEH-FEFDCKN-CVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 4879
Score = 184 bits (467), Expect = 1e-45
Identities = 183/696 (26%), Positives = 271/696 (38%), Gaps = 108/696 (15%)
Query: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKE-E 1980
R R G VC G HY +FDG P C C + +K A H K
Sbjct: 28 RTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGS-----YKEFAVHLKRGP 82
Query: 1981 GGTEA-FRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNI 2039
G EA + + + I D + L + H ++N V+ P S PG+ ++ S Y+ V
Sbjct: 83 GQAEAPAGVESILLTIKDDTIYLTR-HLAVLNGAVVSTPHYS--PGLLIEKSDAYTKVYS 139
Query: 2040 KIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWK 2099
+ G+ + ++ L +E+ T + CG+CG++N + + SD V S EF N K
Sbjct: 140 RAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL-SDGVLFSPLEFGNMQK 198
Query: 2100 DKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDL 2159
D C+ +E+ PA E+ R +CE L A +A C + L
Sbjct: 199 INQPDVVCED--PEEEVAPASCSEH-------------RAECERLLTAEAFADCQDLVPL 243
Query: 2160 TPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTN 2219
P+L C C G +C + F C G +P WR ++ CP CP Y
Sbjct: 244 EPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVY-- 301
Query: 2220 CLPSCSPSCWDLDGRCEGAKVPSACAE----GCICQPGYV---LSEDKCVPRSQCGCKDA 2272
L S SP C D C +V S C E GC C G V + + CVP SQC C+
Sbjct: 302 -LESGSP-CMDT---CSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCR-L 355
Query: 2273 HGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCS 2332
HG G+ +++ C E+CVC G C D CP C+
Sbjct: 356 HGHLYTPGQE-ITNDC-EQCVCNAGRWVCKDLPCPG---------------------TCA 392
Query: 2333 VYGDPRYLTFDGFSYRLQGRMTYVLIKTV--DVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
+ G TFDG +Y G YVL K D E +K ++ + L +
Sbjct: 393 LEGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLGELAPCGSTDKQTCLKTVVLLAD 452
Query: 2391 VITTVYGYKVQLQAGL-ELVVNNQKMAVPY---RPNE-HLRVTLWGQRLYLVTDFELVVS 2445
V +K L EL VN + + RP+ H+ V++ L V
Sbjct: 453 KKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSM-------AIGVRLQVQ 505
Query: 2446 FGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKT--ED 2503
++L +G V GLCGN++ +D SG + F N+W+ ++ D
Sbjct: 506 LAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHD 565
Query: 2504 AL--LRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACH 2561
L L P ++ E A+ + C +L + PF CH
Sbjct: 566 KLDWLDDPCSLNIES-----------------------ANYAEHWCSLLKKTETPFGRCH 602
Query: 2562 QTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGH 2597
V P + + C D C+ Q+ E+ C LS +
Sbjct: 603 SAVDPAEYYKRCKYDTCNCQN---NEDCLCAALSSY 635
Score = 165 bits (417), Expect = 7e-40
Identities = 126/477 (26%), Positives = 199/477 (41%), Gaps = 79/477 (16%)
Query: 1070 CREGCVCNPGFLFSDNH--CIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVEC 1127
C GCVC G L D C+ C C +NND Y GA+ +V+C
Sbjct: 796 CVSGCVCPDG-LMDDGRGGCVVEKECPCVHNNDLYSSGAK---------------IKVDC 839
Query: 1128 QISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C 1186
C K G++ C TC +YG HY+TFDG+++ F G C+Y+ Q C
Sbjct: 840 N--------TCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYC 891
Query: 1187 G-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPS 1245
G NS+ F + +N G GV+C + + + + + L R ++ + A +
Sbjct: 892 GQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTT 951
Query: 1246 KGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKL 1305
+ V G+++ +++ G+ V WD +++ ++ +Y G +CGLCGN+D S+ND
Sbjct: 952 REV-----GQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTR 1006
Query: 1306 DGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPF 1365
D + + GNSW+ E C N C + C L + F
Sbjct: 1007 DHMVVSSELDFGNSWK----EAPTCPDVS-TNPEPCSLNPHRRSWAEKQCSILKSS--VF 1059
Query: 1366 ETCLLHVKAASFFDSCMLDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCP 1423
C V F+++C+ D C G C+ +++ C G V WR P CP
Sbjct: 1060 SICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCP 1118
Query: 1424 MAC----PPNS---KYSLCAKPCPDTC------HSGFSGMF---CSDRCVEACECNPGFV 1467
+ C PP+ Y C +TC HS S + C RC + P +
Sbjct: 1119 IFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKD---RPIYE 1175
Query: 1468 LSGLECIPRSQCGCLHPAGSYFKVGERWYKPG--------CKELCVCESNNRIRCQP 1516
+C+ +CGC V + Y PG CK CVC +++++ C+P
Sbjct: 1176 EDLKKCVTADKCGCY--------VEDTHYPPGASVPTEETCKS-CVCTNSSQVVCRP 1223
Score = 164 bits (414), Expect = 1e-39
Identities = 139/497 (27%), Positives = 206/497 (41%), Gaps = 81/497 (16%)
Query: 1436 AKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLE-CIPRSQCGCLHPAGSYFKVGER 1494
+KP +C + +G + ++ CV C C G + G C+ +C C+H
Sbjct: 777 SKPRALSCQTLAAGYYHTE-CVSGCVCPDGLMDDGRGGCVVEKECPCVH--------NND 827
Query: 1495 WYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFD 1554
Y G K C N C+ R + C Q CH TC+ G HY+TFD
Sbjct: 828 LYSSGAKIKVDC---NTCTCK----RGRWVCTQAV----CHG----TCSIYGSGHYITFD 872
Query: 1555 GALHHFMGTCTYVLTRP-CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISL 1613
G + F G C+YV + C S F + N G V+ KA+ + + + L
Sbjct: 873 GKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCG-TTGVTCSKAIKIFMGRTELKL 931
Query: 1614 LRGCKVMLN---GHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPS 1670
+V++ GH VA T R +++ ++ G+ V +D V + +
Sbjct: 932 EDKHRVVIQRDEGHHVAY---------TTREVGQYLVVESSTGIIVIWDKRTTVFIKLAP 982
Query: 1671 SYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQ 1730
SY G +CGLCGN+++ S +D D + + G +WK P C V P C
Sbjct: 983 SYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWK----EAPTCPDVSTNPEPCS 1038
Query: 1731 ENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG--TKGDTTALCRSLQ 1787
N +W K C+IL FS CH V P+ + +CVH C T GD C ++
Sbjct: 1039 LNPHRRSWAEKQCSIL--KSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVA 1096
Query: 1788 AYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSPCPDTCSSINN------ 1834
+YA C + G WR CP+ C PP Y PC + +TC +IN
Sbjct: 1097 SYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNIS 1156
Query: 1835 --------PRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTE 1886
PR CPK P E + +K CV +CGC +++P G TE
Sbjct: 1157 VSYLEGCYPR-CPKDRPIYEE-DLKK--------CVTADKCGCY-VEDTHYPPGASVPTE 1205
Query: 1887 NTCTRLCTCSVHNNITC 1903
TC + C C+ + + C
Sbjct: 1206 ETC-KSCVCTNSSQVVC 1221
Score = 162 bits (410), Expect = 4e-39
Identities = 156/469 (33%), Positives = 196/469 (41%), Gaps = 83/469 (17%)
Query: 606 TIPSEKPNMPSEKPTIPSEKPTILTEKP--TIPSEKPTIPSEKPTISTEKPTVPTEEPTT 663
T PS PS PT + P T P T + P + P I+T PT P+
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456
Query: 664 PTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEK 723
P TTT PT PS PT PS PT P S T +T PT +P PT
Sbjct: 1457 PISTTTTPP-----PTTTPSPPTTTPSPPTTTP--SPPTTTTTTPPPTTTPSP---PTTT 1506
Query: 724 PTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIP 783
P P +T P PT P+ PT T P PTT PT +P +T PT T+P
Sbjct: 1507 PITPPASTTTLP-----PTTTPSPPTTTTTTPP--PTTTPSPPTTTP--ITPPTSTTTLP 1557
Query: 784 TEKPTIPTEKPTISTEEP--TTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTE 841
T P+ PT +T P TTP+ TT + P+I TTT+ TT +
Sbjct: 1558 --PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTI-----------TTTTPPPTTTPSP 1604
Query: 842 KLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTI 901
T T +T PT PT +P +T PT T+P PT TT S T
Sbjct: 1605 PTT------TTTTPPPTTTPSPPTTTP--ITPPTSTTTLP---PT-----TTPSPPPTTT 1648
Query: 902 PTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEK 961
T PT +P PT +T P I T T P TT S+ T P SP T+ T
Sbjct: 1649 TTPPPTTTPSPPTTTTPSPPITT--TTTPPPTTTPSSPITTTP------SPPTTTMTTPS 1700
Query: 962 PTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHA 1021
PT + P+ P T P+ T P+ PT T PSPT T P
Sbjct: 1701 PTTT---PSSPITTTTTPS-STTTPSPPPTTMTT---------PSPTTT--------PSP 1739
Query: 1022 PSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLC 1070
P+T MT+ + TTT+S +T PP+ + + P S +P C PLC
Sbjct: 1740 PTTTMTT-LPPTTTSSPLTTTPLPPSITPPTFS-PFSTTTPTTPCVPLC 1786
Score = 160 bits (404), Expect = 2e-38
Identities = 147/446 (32%), Positives = 180/446 (40%), Gaps = 64/446 (14%)
Query: 548 VSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTI 607
+++ P TT + +T PT + P+ TT P P T P I+T
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTP------PPTTTPSPPITTTTTPP 1449
Query: 608 PSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEE 667
P+ P+ P T P PT PT PT PT +T P PT TTP+
Sbjct: 1450 PTTTPSPPISTTTTPP--PTTTPSPPTTTPSPPTTTPSPPTTTTTTPP-PT---TTPSPP 1503
Query: 668 TTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIP 727
TTT + P T P PT PS PT T +T PT +P PT T T P
Sbjct: 1504 TTTPITPPASTTTLP--PTTTPSPPT---------TTTTTPPPTTTPSPPT--TTPITPP 1550
Query: 728 TEKSTISPEKPTTPTEKPTIPTEKP-TISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEK 786
T +T+ P TTP+ PT T P T +P PTT T P PTI T
Sbjct: 1551 TSTTTLPPT--TTPSPPPTTTTTPPPTTTPSPPTTTTPSP-------------PTITTTT 1595
Query: 787 PTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIP 846
P PT P+ T TTP TT PS P P P TTT TT S T
Sbjct: 1596 PP-PTTTPSPPTTTTTTPPPTTT-----PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTT 1649
Query: 847 MEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKP 906
PT + PT T P I+ T PT P+ PI TT S T+ T P
Sbjct: 1650 TPPPTTTPSPPTTTTPSPPIT-------TTTTPPPTTTPSSPI-TTTPSPPTTTMTTPSP 1701
Query: 907 TISPEKPTISTEKP---TIPTEKP---TIPTEETTISTEKLTIPTEKPTISPEKLTIPTE 960
T +P P +T P T P+ P T P+ TT S T+ T PT + LT
Sbjct: 1702 TTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPL 1761
Query: 961 KPTISTEKPTIPTEKLTIPTEKPTIP 986
P+I+ PT T PT P +P
Sbjct: 1762 PPSIT--PPTFSPFSTTTPT-TPCVP 1784
Score = 158 bits (399), Expect = 8e-38
Identities = 174/599 (29%), Positives = 229/599 (38%), Gaps = 46/599 (7%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3383 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3439
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3440 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3499
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3500 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3558
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3559 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3615
Query: 705 ISTEKPTISPEKPTI---PTEKPTIPTEKSTISPEKPTT---PTEKPTIPTEKPTISPEK 758
T+ PT +P T PT PT T+ T +P TT PT PT T+ PT +P
Sbjct: 3616 TGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPIT 3673
Query: 759 PTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-I 817
TT T PT +P PT P I T PT PT + TTP TT T P+
Sbjct: 3674 TTT-TVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3731
Query: 818 PMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEK 877
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3732 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3791
Query: 878 LTIPTEKPTIPIEETT--ISTEKLTIPTEKPT--ISPEKPTISTEKPTIPTEKPTIPTEE 933
PT PT TT I+T PT PT +P I+T PT PT
Sbjct: 3792 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3851
Query: 934 TT--ISTEKLTIPTEKPT---------ISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEK 982
TT I+T PT PT I+ PT PT + T P T T
Sbjct: 3852 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3911
Query: 983 PTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
PT PT T T +T P+PT TG +P +T +T T T + ++T
Sbjct: 3912 PT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3969
Score = 158 bits (399), Expect = 8e-38
Identities = 174/599 (29%), Positives = 229/599 (38%), Gaps = 46/599 (7%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3406 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3462
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3463 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3522
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3523 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3581
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3582 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3638
Query: 705 ISTEKPTISPEKPTI---PTEKPTIPTEKSTISPEKPTT---PTEKPTIPTEKPTISPEK 758
T+ PT +P T PT PT T+ T +P TT PT PT T+ PT +P
Sbjct: 3639 TGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPIT 3696
Query: 759 PTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-I 817
TT T PT +P PT P I T PT PT + TTP TT T P+
Sbjct: 3697 TTT-TVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3754
Query: 818 PMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEK 877
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3755 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3814
Query: 878 LTIPTEKPTIPIEETT--ISTEKLTIPTEKPT--ISPEKPTISTEKPTIPTEKPTIPTEE 933
PT PT TT I+T PT PT +P I+T PT PT
Sbjct: 3815 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3874
Query: 934 TT--ISTEKLTIPTEKPT---------ISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEK 982
TT I+T PT PT I+ PT PT + T P T T
Sbjct: 3875 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3934
Query: 983 PTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
PT PT T T +T P+PT TG +P +T +T T T + ++T
Sbjct: 3935 PT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3992
Score = 158 bits (399), Expect = 8e-38
Identities = 174/599 (29%), Positives = 229/599 (38%), Gaps = 46/599 (7%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3429 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3485
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3486 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3545
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3546 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3604
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3605 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3661
Query: 705 ISTEKPTISPEKPTI---PTEKPTIPTEKSTISPEKPTT---PTEKPTIPTEKPTISPEK 758
T+ PT +P T PT PT T+ T +P TT PT PT T+ PT +P
Sbjct: 3662 TGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPIT 3719
Query: 759 PTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-I 817
TT T PT +P PT P I T PT PT + TTP TT T P+
Sbjct: 3720 TTT-TVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3777
Query: 818 PMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEK 877
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3778 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3837
Query: 878 LTIPTEKPTIPIEETT--ISTEKLTIPTEKPT--ISPEKPTISTEKPTIPTEKPTIPTEE 933
PT PT TT I+T PT PT +P I+T PT PT
Sbjct: 3838 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3897
Query: 934 TT--ISTEKLTIPTEKPT---------ISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEK 982
TT I+T PT PT I+ PT PT + T P T T
Sbjct: 3898 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3957
Query: 983 PTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
PT PT T T +T P+PT TG +P +T +T T T + ++T
Sbjct: 3958 PT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4015
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 1911 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 1967
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 1968 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2027
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2028 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2086
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2087 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2143
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2144 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2201
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2202 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2261
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2262 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2321
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2322 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2381
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2382 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2438
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2439 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2487
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 1934 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 1990
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 1991 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2050
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2051 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2109
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2110 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2166
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2167 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2224
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2225 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2284
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2285 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2344
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2345 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2404
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2405 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2461
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2462 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2510
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 1957 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2013
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2014 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2073
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2074 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2132
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2133 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2189
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2190 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2247
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2248 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2307
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2308 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2367
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2368 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2427
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2428 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2484
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2485 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2533
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 1980 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2036
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2037 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2096
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2097 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2155
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2156 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2212
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2213 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2270
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2271 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2330
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2331 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2390
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2391 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2450
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2451 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2507
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2508 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2556
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2003 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2059
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2060 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2119
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2120 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2178
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2179 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2235
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2236 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2293
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2294 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2353
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2354 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2413
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2414 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2473
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2474 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2530
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2531 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2579
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2026 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2082
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2083 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2142
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2143 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2201
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2202 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2258
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2259 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2316
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2317 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2376
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2377 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2436
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2437 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2496
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2497 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2553
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2554 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2602
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2049 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2105
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2106 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2165
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2166 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2224
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2225 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2281
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2282 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2339
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2340 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2399
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2400 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2459
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2460 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2519
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2520 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2576
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2577 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2625
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2072 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2128
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2129 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2188
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2189 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2247
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2248 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2304
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2305 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2362
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2363 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2422
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2423 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2482
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2483 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2542
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2543 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2599
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2600 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2648
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2095 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2151
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2152 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2211
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2212 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2270
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2271 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2327
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2328 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2385
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2445
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2446 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2505
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2506 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2565
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2566 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2622
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2623 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2671
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2118 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2174
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2175 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2234
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2235 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2293
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2294 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2350
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2351 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2408
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2409 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2468
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2469 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2528
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2529 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2588
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2589 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2645
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2646 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2694
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2141 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2197
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2198 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2257
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2258 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2316
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2317 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2373
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2374 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2431
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2432 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2491
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2492 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2551
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2552 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2611
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2668
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2669 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2717
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2164 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2220
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2221 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2280
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2281 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2339
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2340 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2396
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2397 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2454
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2455 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2514
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2515 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2574
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2575 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2634
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2635 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2691
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2692 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2740
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2187 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2243
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2244 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2303
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2304 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2362
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2363 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2419
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2420 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2477
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2478 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2537
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2538 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2597
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2598 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2657
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2658 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2714
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2715 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2763
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2210 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2266
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2267 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2326
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2327 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2385
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2442
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2443 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2500
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2501 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2560
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2561 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2620
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2621 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2680
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2681 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2737
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2738 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2786
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2233 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2289
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2290 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2349
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2350 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2408
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2409 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2465
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2466 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2523
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2524 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2583
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2584 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2643
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2644 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2703
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2704 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2760
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2761 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2809
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2256 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2312
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2313 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2372
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2373 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2431
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2432 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2488
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2489 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2546
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2547 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2606
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2607 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2666
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2667 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2726
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2727 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2783
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2784 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2832
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2279 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2335
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2336 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2395
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2396 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2454
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2455 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2511
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2512 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2569
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2570 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2629
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2630 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2689
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2690 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2749
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2750 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2806
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2807 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2855
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2302 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2358
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2359 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2418
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2419 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2477
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2478 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2534
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2535 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2592
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2593 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2652
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2653 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2712
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2713 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2772
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2773 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2829
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2830 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2878
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2325 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2381
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2382 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2441
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2442 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2500
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2501 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2557
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2558 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2615
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2616 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2675
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2676 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2735
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2736 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2795
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2796 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2852
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2853 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2901
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2348 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2404
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2405 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2464
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2465 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2523
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2524 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2580
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2581 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2638
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2639 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2698
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2699 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2758
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2759 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2818
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2819 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2875
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2876 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2924
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2371 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2427
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2428 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2487
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2488 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2546
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2547 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2603
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2604 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2661
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2662 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2721
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2722 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2781
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2782 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2841
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2842 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2898
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2899 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2947
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2394 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2450
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2451 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2510
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2511 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2569
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2570 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2626
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2627 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2684
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2685 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2744
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2745 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2804
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2805 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2864
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2865 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2921
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2922 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2970
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2417 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2473
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2474 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2533
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2534 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2592
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2593 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2649
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2650 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2707
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2708 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2767
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2768 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2827
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2828 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2887
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2888 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2944
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2945 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2993
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2440 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2496
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2497 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2556
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2557 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2615
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2616 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2672
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2673 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2730
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2731 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2790
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2791 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2850
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2851 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2910
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2911 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2967
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2968 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3016
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2463 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2519
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2520 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2579
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2580 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2638
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2639 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2695
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2696 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2753
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2754 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2813
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2814 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2873
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2874 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2933
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2934 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 2990
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2991 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3039
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2486 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2542
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2543 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2602
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2603 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2661
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2662 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2718
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2719 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2776
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2777 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2836
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2837 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2896
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2897 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2956
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2957 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3013
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3014 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3062
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2509 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2565
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2566 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2625
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2626 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2684
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2685 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2741
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2742 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2799
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2800 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2859
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2860 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2919
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2920 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2979
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 2980 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3036
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3037 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3085
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2532 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2588
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2589 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2648
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2649 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2707
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2708 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2764
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2765 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2822
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2823 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2882
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2883 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2942
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2943 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3002
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3003 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3059
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3060 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3108
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2555 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2611
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2671
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2672 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2730
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2731 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2787
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2788 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2845
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2846 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2905
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2906 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2965
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2966 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3025
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3026 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3082
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3083 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3131
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2578 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2634
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2635 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2694
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2695 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2753
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2754 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2810
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2811 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2868
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2869 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2928
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2929 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2988
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 2989 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3048
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3049 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3105
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3106 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3154
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2601 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2657
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2658 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2717
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2718 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2776
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2777 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2833
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2834 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2891
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2892 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2951
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2952 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3011
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3012 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3071
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3072 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3128
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3129 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3177
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2624 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2680
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2681 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2740
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2741 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2799
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2800 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2856
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2857 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2914
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2915 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2974
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2975 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3034
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3035 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3094
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3095 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3151
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3152 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3200
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2647 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2703
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2704 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2763
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2764 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2822
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2823 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2879
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2880 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2937
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2938 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2997
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2998 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3057
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3058 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3117
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3118 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3174
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3175 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3223
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2670 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2726
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2727 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2786
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2787 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2845
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2846 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2902
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2903 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2960
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2961 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3020
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3021 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3080
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3081 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3140
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3141 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3197
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3198 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3246
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2693 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2749
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2750 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2809
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2810 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2868
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2869 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2925
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2926 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2983
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2984 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3043
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3044 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3103
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3104 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3163
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3164 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3220
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3221 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3269
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2716 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2772
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2773 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2832
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2833 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2891
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2892 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2948
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2949 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3006
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3007 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3066
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3067 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3126
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3127 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3186
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3187 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3243
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3244 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3292
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2739 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2795
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2796 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2855
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2856 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2914
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2915 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2971
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2972 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3029
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3030 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3089
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3090 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3149
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3150 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3209
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3210 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3266
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3267 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3315
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2762 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2818
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2819 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2878
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2879 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2937
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2938 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 2994
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 2995 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3052
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3053 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3112
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3113 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3172
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3173 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3232
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3233 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3289
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3290 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3338
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2785 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2841
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2842 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2901
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2902 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2960
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2961 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3017
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3018 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3075
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3076 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3135
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3136 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3195
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3196 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3255
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3256 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3312
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3313 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3361
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2808 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2864
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2865 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2924
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2925 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2983
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 2984 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3040
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3041 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3098
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3099 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3158
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3159 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3218
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3219 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3278
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3279 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3335
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3336 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3384
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2831 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2887
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2888 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2947
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2948 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3006
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3007 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3063
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3064 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3121
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3122 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3181
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3182 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3241
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3242 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3301
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3302 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3358
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3359 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3407
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2854 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2910
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2911 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2970
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2971 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3029
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3030 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3086
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3087 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3144
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3145 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3204
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3205 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3264
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3265 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3324
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3325 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3381
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3382 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3430
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2877 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2933
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2934 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2993
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 2994 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3052
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3053 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3109
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3110 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3167
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3168 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3227
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3228 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3287
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3288 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3347
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3348 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3404
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3405 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3453
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2900 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2956
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2957 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3016
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3017 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3075
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3076 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3132
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3133 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3190
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3191 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3250
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3251 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3310
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3311 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3370
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3371 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3427
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3428 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3476
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2923 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2979
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 2980 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3039
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3040 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3098
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3099 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3155
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3156 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3213
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3214 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3273
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3274 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3333
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3334 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3393
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3394 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3450
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3451 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3499
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2946 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3002
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3003 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3062
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3063 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3121
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3122 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3178
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3179 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3236
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3237 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3296
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3297 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3356
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3357 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3416
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3417 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3473
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3474 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3522
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2969 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3025
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3026 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3085
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3086 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3144
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3145 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3201
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3202 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3259
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3260 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3319
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3320 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3379
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3380 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3439
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3440 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3496
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3497 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3545
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 2992 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3048
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3049 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3108
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3109 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3167
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3168 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3224
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3225 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3282
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3283 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3342
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3343 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3402
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3403 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3462
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3463 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3519
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3520 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3568
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3015 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3071
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3072 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3131
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3132 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3190
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3191 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3247
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3248 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3305
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3306 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3365
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3366 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3425
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3426 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3485
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3486 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3542
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3543 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3591
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3038 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3094
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3095 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3154
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3155 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3213
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3214 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3270
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3271 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3328
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3329 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3388
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3389 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3448
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3449 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3508
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3509 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3565
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3566 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3614
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3061 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3117
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3118 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3177
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3178 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3236
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3237 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3293
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3294 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3351
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3352 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3411
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3412 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3471
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3472 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3531
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3532 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3588
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3589 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3637
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3084 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3140
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3141 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3200
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3201 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3259
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3260 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3316
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3317 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3374
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3375 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3434
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3435 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3494
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3495 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3554
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3555 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3611
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3612 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3660
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3107 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3163
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3164 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3223
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3224 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3282
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3283 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3339
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3340 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3397
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3398 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3457
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3458 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3517
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3518 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3577
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3578 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3634
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3635 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3683
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3130 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3186
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3187 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3246
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3247 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3305
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3306 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3362
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3363 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3420
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3421 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3480
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3481 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3540
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3541 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3600
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3601 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3657
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3658 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3706
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3153 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3209
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3210 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3269
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3270 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3328
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3329 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3385
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3386 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3443
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3444 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3503
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3504 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3563
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3564 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3623
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3624 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3680
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3681 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3729
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3176 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3232
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3233 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3292
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3293 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3351
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3352 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3408
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3409 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3466
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3467 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3526
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3527 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3586
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3587 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3646
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3647 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3703
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3704 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3752
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3199 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3255
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3256 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3315
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3316 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3374
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3375 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3431
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3432 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3489
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3490 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3549
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3550 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3609
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3610 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3669
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3670 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3726
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3727 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3775
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3222 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3278
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3279 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3338
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3339 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3397
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3398 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3454
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3455 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3512
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3513 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3572
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3573 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3632
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3633 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3692
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3693 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3749
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3750 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3798
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3245 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3301
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3302 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3361
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3362 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3420
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3421 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3477
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3478 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3535
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3536 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3595
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3596 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3655
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3656 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3715
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3716 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3772
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3773 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3821
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3268 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3324
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3325 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3384
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3385 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3443
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3444 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3500
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3501 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3558
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3559 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3618
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3619 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3678
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3679 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3738
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3739 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3795
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3796 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3844
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3291 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3347
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3348 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3407
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3408 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3466
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3467 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3523
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3524 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3581
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3582 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3641
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3642 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3701
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3702 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3761
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3762 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3818
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3819 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3867
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3314 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3370
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3371 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3430
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3431 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3489
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3490 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3546
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3547 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3604
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3605 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3664
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3665 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3724
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3725 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3784
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3785 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3841
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3842 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3890
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3337 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3393
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3394 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3453
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3454 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3512
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3513 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3569
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3570 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3627
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3628 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3687
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3688 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3747
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3748 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3807
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3808 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3864
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3865 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3913
Score = 157 bits (396), Expect = 2e-37
Identities = 172/589 (29%), Positives = 224/589 (38%), Gaps = 36/589 (6%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3360 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3416
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3417 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3476
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3477 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3535
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3536 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3592
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-T 763
T+ PT +P T T PT PT T +P T PT PT + TTP T
Sbjct: 3593 TGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3650
Query: 764 EKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPM 819
T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 3651 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3710
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLT 879
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 3711 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3770
Query: 880 IPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTEETT 935
PT PT TT I+T PT P T +P I+T PT PT TT
Sbjct: 3771 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3830
Query: 936 --ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993
I+T PT PT + T P T T PT PT T PT P I T P
Sbjct: 3831 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTTVTP 3887
Query: 994 TEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T + P +P T T +P TP T+ I TTT + + T
Sbjct: 3888 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3936
Score = 155 bits (393), Expect = 4e-37
Identities = 163/546 (29%), Positives = 213/546 (39%), Gaps = 56/546 (10%)
Query: 531 PGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEK 590
P T P + P ++ P +T T PT + PT + P+ T PT
Sbjct: 1434 PTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTT 1493
Query: 591 PTIPTEKPTISTEKP-TIPSEKPNMPSEKPTIPSEKPTILTEKP---TIPSEKPTIPSEK 646
P PT P+ T P T P+ +P PT PT T P T PS T P
Sbjct: 1494 PP-PTTTPSPPTTTPITPPASTTTLP---PTTTPSPPTTTTTTPPPTTTPSPPTTTPITP 1549
Query: 647 PTISTEKP--TVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
PT +T P T P+ PTT T T+ P T PS PT + P T S T
Sbjct: 1550 PTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPP-TTTTPSPPTITTTTPPPTTTPSPPTTT 1608
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKP-TIPTEKPTISPEKPTTPT 763
+T PT +P PT T T PT +T+ P TTP+ P T T PT +P PTT T
Sbjct: 1609 TTTPPPTTTPSPPT--TTPITPPTSTTTLPP--TTTPSPPPTTTTTPPPTTTPSPPTTTT 1664
Query: 764 EKPTISPEKLTIPTEKPTIP-TEKPTIPTEKPTISTEEPTT------PTEETTISTEKPS 816
P I+ PT P+ P T P+ PT T++T PTT T T ST PS
Sbjct: 1665 PSPPITTTTTPPPTTTPSSPITTTPSPPT--TTMTTPSPTTTPSSPITTTTTPSSTTTPS 1722
Query: 817 IPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTE 876
P T P+ TT S TT++T T T + P+I PT SP T PT
Sbjct: 1723 PPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSI--TPPTFSPFSTTTPT- 1779
Query: 877 KLTIPTEKPTIPIEETTISTEKLTIPTEKP---------TISPEKPTISTEKPTIPTEKP 927
P +P+ T + KP P + + T+ + P
Sbjct: 1780 -------TPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVP 1832
Query: 928 TIPTEETTISTEKLTI----PTEKP-TISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEK 982
+T + + + +KP + P + E E T PT T TE
Sbjct: 1833 IGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTEN 1892
Query: 983 PTIPTEKP------TIPTEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTT 1035
PT PT P PT T + P +P T T +P TP T+ I TTT
Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1952
Query: 1036 TSRSST 1041
+ + T
Sbjct: 1953 VTPTPT 1958
Score = 154 bits (389), Expect = 1e-36
Identities = 164/545 (30%), Positives = 210/545 (38%), Gaps = 33/545 (6%)
Query: 521 VVAMGFIL---INPGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKP 577
V+ M F L IN C P + + P TT +T T++ + P
Sbjct: 1860 VIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTP 1919
Query: 578 S---VTTEKPTVPKEKPTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTE 631
+ +TT P PT T+ PT I+T P+ P T P T +T
Sbjct: 1920 TTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1978
Query: 632 KPTIPSEKPTIPSEKPTISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEK 688
PT + + T +T PT T+ PTT TTT++ PT + PT
Sbjct: 1979 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTT 2037
Query: 689 PSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIP 748
P T T++ T T+ PT +P T T PT PT T +P T P
Sbjct: 2038 PITTTT--TVTPTPTPTGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTP 2093
Query: 749 TEKPTISPEKPTTP-TEKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTP 804
T PT + TTP T T++P T+ PT I T PT PT + TTP
Sbjct: 2094 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2153
Query: 805 TEETTISTEKPS-IPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEK 863
TT T P+ + PT TTT+V T T T T +T PT
Sbjct: 2154 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2213
Query: 864 PTISPEKLTIPTEKLTIPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEK 919
T +P I T PT PT TT I+T PT P T +P I+T
Sbjct: 2214 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2273
Query: 920 PTIPTEKPTIPTEETT--ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLT 977
PT PT TT I+T PT PT + T P T T PT PT T
Sbjct: 2274 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT 2332
Query: 978 IPTEKPTIPTEKPTIPTEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTT 1036
PT P I T PT T + P +P T T +P TP T+ I TTT
Sbjct: 2333 -PTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2390
Query: 1037 SRSST 1041
+ + T
Sbjct: 2391 TPTPT 2395
Score = 154 bits (389), Expect = 1e-36
Identities = 160/532 (30%), Positives = 206/532 (38%), Gaps = 30/532 (5%)
Query: 531 PGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVP 587
P T P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 1896 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1955
Query: 588 KEKPTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPS 644
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 1956 TPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2014
Query: 645 EKPTISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISME 701
T +T PT T+ PTT TTT++ PT + PT P T T++
Sbjct: 2015 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPT 2071
Query: 702 ETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTT 761
T T+ PT +P T T PT PT T +P T PT PT + TT
Sbjct: 2072 PTPTGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2129
Query: 762 P-TEKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS- 816
P T T++P T+ PT I T PT PT + TTP TT T P+
Sbjct: 2130 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2189
Query: 817 IPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTE 876
+ PT TTT+V T T T T +T PT T +P I T
Sbjct: 2190 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2249
Query: 877 KLTIPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIPTE 932
PT PT TT I+T PT P T +P I+T PT PT
Sbjct: 2250 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2309
Query: 933 ETT--ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKP 990
TT I+T PT PT + T P T T PT PT T PT P I T
Sbjct: 2310 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQT-PTTTP-ITTTTT 2366
Query: 991 TIPTEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
PT T + P +P T T +P TP T+ I TTT + + T
Sbjct: 2367 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2418
Score = 153 bits (387), Expect = 2e-36
Identities = 137/428 (32%), Positives = 167/428 (39%), Gaps = 59/428 (13%)
Query: 544 PVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS-VTTEKP--TVPKEKPTIPTEKPTI 600
P P ++ P T+ T PT + PT + P TT P T P T P I
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458
Query: 601 STEKPTIPSEKPNMPSEKPTIPS---EKPTILTEKP---TIPSEKPTIPSEKPTISTEKP 654
ST P+ P+ P+ P+ P+ PT T P T PS T P P +T P
Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP 1518
Query: 655 TVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISP 714
PT P+ PT TTT PT PS PT P P T +T PT +P
Sbjct: 1519 --PTTTPSPPTTTTTTPP-----PTTTPSPPTTTPITP---------PTSTTTLPPTTTP 1562
Query: 715 EKPTIPTEKPTIPTEKSTISPEKPTTPTEKP---TIPTEKPTISPEKPTTPTEKPTISPE 771
P PT T T T +P PTT T P T T PT +P PTT T +P
Sbjct: 1563 SPP--PT---TTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTT----TTTTPP 1613
Query: 772 KLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTT 831
T P+ T P PT T P +T P T T T PS P P TTT
Sbjct: 1614 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT 1673
Query: 832 SVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEE 891
+ TT + +T PT T+ T PT +P P T P
Sbjct: 1674 TPPPTTTPSSPITTTPSPPT-----TTMTTPSPTTTPSS----------PITTTTTPSST 1718
Query: 892 TTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTIS 951
TT S T+ T PT +P PT T+ T PT T + ++T L PT S
Sbjct: 1719 TTPSPPPTTMTTPSPTTTPSPPT-----TTMTTLPPT--TTSSPLTTTPLPPSITPPTFS 1771
Query: 952 PEKLTIPT 959
P T PT
Sbjct: 1772 PFSTTTPT 1779
Score = 152 bits (384), Expect = 4e-36
Identities = 170/553 (30%), Positives = 212/553 (38%), Gaps = 37/553 (6%)
Query: 512 GIQGSNTASVVAMGFILINPGTCPVKVLP-------ELPPVSPVSSTGPSE-TTGLTENP 563
G G V++G I N P V+P E+ T P+ TT TENP
Sbjct: 1834 GQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENP 1893
Query: 564 TISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPS 623
T T P + TT PT PT P I+T P+ P T P
Sbjct: 1894 TPPTTTPITT-----TTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPI 1947
Query: 624 EKPTILTEKPTIPSEKPTIPSEKPTISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTE 680
T +T PT + + T +T PT T+ PTT TTT++ PT
Sbjct: 1948 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2007
Query: 681 KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTT 740
+ PT P T T++ T T+ PT +P T T PT PT T +P
Sbjct: 2008 TQT-PTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTT-TVTPT-PTPTGTQTPTTTPI 2062
Query: 741 PTEKPTIPTEKPTISPEKPTTP-TEKPTISPEKLTIPTEKPT---IPTEKPTIPTEKPTI 796
T PT PT + TTP T T++P T+ PT I T PT PT
Sbjct: 2063 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2122
Query: 797 STEEPTTPTEETTISTEKPS-IPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTE 855
+ TTP TT T P+ + PT TTT+V T T T T +T
Sbjct: 2123 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2182
Query: 856 KPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPE 911
PT T +P I T PT PT TT I+T PT P T +P
Sbjct: 2183 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2242
Query: 912 KPTISTEKPTIPTEKPTIPTEETT--ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKP 969
I+T PT PT TT I+T PT PT + T P T T P
Sbjct: 2243 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2302
Query: 970 TIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSP-TATGLAALVMSPHAPSTPMTS 1028
T PT T PT P I T PT T + P +P T T +P TP T+
Sbjct: 2303 T-PTGTQT-PTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2359
Query: 1029 VILGTTTTSRSST 1041
I TTT + + T
Sbjct: 2360 PITTTTTVTPTPT 2372
Score = 152 bits (384), Expect = 4e-36
Identities = 187/663 (28%), Positives = 248/663 (37%), Gaps = 83/663 (12%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3613 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3669
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3670 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3729
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3730 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3788
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3789 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3845
Query: 705 ISTEKPTISPEKPTI---PTEKPTIPTEKSTISPEKPTT---PTEKPTIPTEKPTISPEK 758
T+ PT +P T PT PT T+ T +P TT PT PT T+ PT +P
Sbjct: 3846 TGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPIT 3903
Query: 759 PTT-----PTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPT---ISTEEPTTPTEETTI 810
TT PT T +P I T PT PT T+ PT I+T TPT T
Sbjct: 3904 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTG 3962
Query: 811 STEKPSIPMEKPT----LPTEETTTSVEETTISTEKLTIPMEKPT---------ISTEKP 857
+ + P+ T PT T + T I+T P PT I+T
Sbjct: 3963 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4022
Query: 858 TIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISP---EKPT 914
PT PT + T P T T PT +T +T T T PT +P + PT
Sbjct: 4023 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4082
Query: 915 ---ISTEKPTIPTEKPTIPTEETT--ISTEKLTIPTEKPT---------ISPEKLTIPTE 960
I+T PT PT TT I+T PT PT I+ PT
Sbjct: 4083 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4142
Query: 961 KPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATG--------- 1011
PT + T P T T PT PT T T +T P+PT TG
Sbjct: 4143 TPTGTQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHT 4201
Query: 1012 ----LAALVMS--PHAPSTPMTSVILGT-TTTSRSSTERCPPNARYESCACPASCKSPRP 1064
+A L S P STP TS + T S + PP S A P++ +P
Sbjct: 4202 STAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTT 4261
Query: 1065 SCG 1067
+ G
Sbjct: 4262 TSG 4264
Score = 151 bits (381), Expect = 1e-35
Identities = 190/682 (27%), Positives = 257/682 (37%), Gaps = 69/682 (10%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 3705 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 3761
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T TT +T T++ + P+ +TT P
Sbjct: 3762 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3821
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + +
Sbjct: 3822 PT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3880
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PTT TTT++ PT + PT P T T++ T
Sbjct: 3881 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTT--TVTPTPTP 3937
Query: 705 ISTEKPTISPEKPTI---PTEKPTIPTEKSTISPEKPTT---PTEKPTIPTEKPTISPEK 758
T+ PT +P T PT PT T+ T +P TT PT PT T+ PT +P
Sbjct: 3938 TGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPIT 3995
Query: 759 PTT---PTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKP 815
TT PT PT + T P I T PT PT + TTP TT T P
Sbjct: 3996 TTTTVTPTPTPTGTQTPTTTP-----ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4050
Query: 816 S-IPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIP 874
+ + PT TTT+V T T T T +T PT T +P I
Sbjct: 4051 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4110
Query: 875 TEKLTIPTEKPTIPIEETT--ISTEKLTIPTEKP--TISPEKPTISTEKPTIPTEKPTIP 930
T PT PT TT I+T PT P T +P I+T PT PT
Sbjct: 4111 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4170
Query: 931 TEETT--ISTEKLTIPTEKPTIS-----PEKLTIPTEKPTISTEKPTIPTEKLTIPTEKP 983
TT I+T PT PT + T P + T S P T + + T P
Sbjct: 4171 QTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSP 4230
Query: 984 TIPTEKPTI-----PTEKLTALRPPH--PSPTAT-GLAALVMSPHAPSTPMTSVILGTTT 1035
TE T+ P ++T+ PP +PT T G L P ++P + GTTT
Sbjct: 4231 L--TESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTT 4288
Query: 1036 TSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNC 1095
S S+ P + ++ A +P P P P + S C C
Sbjct: 4289 GSSSA----PTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRP-YPSSVLIC-------C 4336
Query: 1096 FYNNDYYEPGAEWFSPNCTEHC 1117
N+ YY PG E ++ + C
Sbjct: 4337 VLNDTYYAPGEEVYNGTYGDTC 4358
Score = 147 bits (372), Expect = 1e-34
Identities = 127/510 (24%), Positives = 197/510 (38%), Gaps = 54/510 (10%)
Query: 1032 GTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCRE----GCVCNPGFLFSD--- 1084
G T+ + CP N Y P LC E GC C G ++ D
Sbjct: 283 GNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGD 342
Query: 1085 NHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQ 1144
+ C+ S C+C + Y PG E N E C C G+
Sbjct: 343 SGCVPVSQCHCRLHGHLYTPGQE--ITNDCEQCVC---------------------NAGR 379
Query: 1145 YGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG 1204
+ C TC + G H TFDG+ + F G C Y+LA+ G+ D + +
Sbjct: 380 WVCKDLPCPGTCALEGGSHITTFDGKTYTFHGDCYYVLAK--GDHNDSYALLGELAPCGS 437
Query: 1205 QEGVSCLSKVYVTL--PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTE 1262
+ +CL V + ++ V L+ QV LP + + S + +
Sbjct: 438 TDKQTCLKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMA 497
Query: 1263 FGLR--VRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSW 1320
G+R V+ QL+VT+ G++ GLCGN++G +D G N+W
Sbjct: 498 IGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTW 557
Query: 1321 QTDQDEDQEC-QKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFD 1379
+ C K ++ P C +++S+ +C L T PF C V A ++
Sbjct: 558 KA----QSSCHDKLDWLDDP-CSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYK 612
Query: 1380 SCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM---ACPPNSKYSLCA 1436
C D C Q + LC +S+ C G + WRE H C +CP + +
Sbjct: 613 RCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWRE-HVCNKDVGSCPNSQVFLYNL 671
Query: 1437 KPCPDTCHS-GFSGMFCSD--RCVEACEC-NPGFVLSGLECIPRSQCGCLHPAGSYFKVG 1492
C TC S + C + V+ C C + F+ C+P ++C C H G Y + G
Sbjct: 672 TTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYH-RGLYLEAG 730
Query: 1493 ERWYKPGCKELCVCESNNRIRCQPWRCRAQ 1522
+ + +E CVC + R+ C+ R Q
Sbjct: 731 DVVVRQ--EERCVCR-DGRLHCRQIRLIGQ 757
Score = 145 bits (366), Expect = 5e-34
Identities = 173/611 (28%), Positives = 226/611 (36%), Gaps = 108/611 (17%)
Query: 531 PGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKP-SVTTEKP---TV 586
P T P+ + P ++ P TT T PT + PT + P ++TT P T
Sbjct: 1542 PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTT 1601
Query: 587 PKEKPTIPTEKPTISTEKP--TIPSEKPNMPSEKP--TIPSEKPTILTEKP--TIPSEKP 640
P T T P +T P T P P + P T PS PT T P T PS P
Sbjct: 1602 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSP-P 1660
Query: 641 TIPSEKPTISTEKPTVPTEEPTTPTEET----TTSMEEPVIPTEKPSIPTEKPSIPTEKP 696
T + P I+T PT P++P T TT+M P PT PS P + P+
Sbjct: 1661 TTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPS-PTTTPSSPITTTTTPSSTT 1719
Query: 697 TISMEETIISTEKPTISPEKPT--IPTEKPTIPTEKSTISPEKP------------TTPT 742
T S T ++T PT +P PT + T PT + T +P P TTPT
Sbjct: 1720 TPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPT 1779
Query: 743 --------------------EKPTIPTE----------------KPTISPEKPTTPTEKP 766
KP TE + T+ P+ P +
Sbjct: 1780 TPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQT 1839
Query: 767 TISPEKLTI----PTEKP--TIPT-------------EKPTIPTEKPTISTEEPTTPTEE 807
+ + + +KP IP E T PT T +TE PT PT
Sbjct: 1840 VVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTT- 1898
Query: 808 TTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLT-IPMEKPT---ISTEKPTIPTEK 863
T I+T P PT TTT + TT T T + PT I+T PT
Sbjct: 1899 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1958
Query: 864 PTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIP 923
PT + T P T T PT +T +T T T PT +P T+ PT
Sbjct: 1959 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----GTQTPTT- 2013
Query: 924 TEKPTIPTEETTISTEKLTIPTEKPTISPEKLTI---PTEKPTISTEKPTIPTEKLTIPT 980
T T TT++ T+ PT +P T PT PT + T P T T
Sbjct: 2014 ----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2069
Query: 981 EKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGT-----TT 1035
PT PT T T +T P+PT TG +P +T +T T TT
Sbjct: 2070 PTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2128
Query: 1036 TSRSSTERCPP 1046
T ++T P
Sbjct: 2129 TPITTTTTVTP 2139
Score = 136 bits (342), Expect = 3e-31
Identities = 158/532 (29%), Positives = 210/532 (39%), Gaps = 67/532 (12%)
Query: 529 INPGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVS-IEKPSVTTEKPTVP 587
I P + P P P TT T PT + PT + I P+ TT P
Sbjct: 1508 ITPPASTTTLPPTTTPSPPT-------TTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT- 1559
Query: 588 KEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
T P+ PT +T P P+ P+ P+ T PS PTI T P PT P
Sbjct: 1560 ----TTPSPPPTTTTTPP--PTTTPSPPT--TTTPS-PPTITTTTP-----PPTTTPSPP 1605
Query: 648 TISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIST 707
T +T P PT TTP+ TTT + P T P PT PS P T +T
Sbjct: 1606 TTTTTTPP-PT---TTPSPPTTTPITPPTSTTTLP--PTTTPSPP---------PTTTTT 1650
Query: 708 EKPTISPEKPTIPTEKPTIPTEKS---TISPEKPTTPTEKP---TIPTEKPTISPEKP-- 759
PT +P PT T P I T + T +P P T T P T+ T PT +P P
Sbjct: 1651 PPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPIT 1710
Query: 760 --TTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSI 817
TTP+ T SP T+ T PT PT T++T PTT + T + PSI
Sbjct: 1711 TTTTPSSTTTPSPPPTTMTTPSPTTTPSPPT-----TTMTTLPPTTTSSPLTTTPLPPSI 1765
Query: 818 PMEKPTL-PTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTE--KPTISPEKLTIP 874
PT P TT + + + KP KP TE P
Sbjct: 1766 --TPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNF--HKPGGDTELIGDVCGPGWAANI 1821
Query: 875 TEKLTIPTEKPTIPIEETTISTEKLTI----PTEKP-TISPEKPTISTEKPTIPTEKPTI 929
+ + T+ + P + +T + + + +KP + P ++ E E T
Sbjct: 1822 SCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQ 1881
Query: 930 PTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEK 989
PT TT +TE T PT P + +T PT PT + T P T T PT PT
Sbjct: 1882 PTTMTTTTTENPTPPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPT-PTGT 1939
Query: 990 PTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
T T +T P+PT TG +P +T +T T T + ++T
Sbjct: 1940 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1991
Score = 128 bits (321), Expect = 9e-29
Identities = 119/455 (26%), Positives = 171/455 (37%), Gaps = 52/455 (11%)
Query: 1493 ERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIY--------GC--HAQGAATC 1542
E W+ C + C+ NN + C +G+ GC H + C
Sbjct: 4423 ETWWLCDCF-MATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYC 4481
Query: 1543 TASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFV--------------VSATNE 1588
T GDPHY+TFDG + + G CTYVL S S D++ V T
Sbjct: 4482 TGWGDPHYVTFDGLYYSYQGNCTYVLVEEI-SPSVDNFGVYIDNYHCDPNDKVSCPRTLI 4540
Query: 1589 NRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLL 1648
R EV IK VH+ + +V +N VALP + G + N V+
Sbjct: 4541 VRHETQEV-LIKTVHMMPMQV--------QVQVNRQAVALP-YKKYGLEVYQSGINYVVD 4590
Query: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708
G+ V Y+G +G G CG N + DD + P ++ +
Sbjct: 4591 IPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQ 4650
Query: 1709 WKLPESSEPGC---FLVGGKPSSCQENSMADAWNKNCA----ILINPQGPFSQCHQVVPP 1761
W + + S+P C +P+ +K+C + F+QCH +VPP
Sbjct: 4651 WLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPP 4710
Query: 1762 QSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTF--CPMRCPPGSSYS 1819
Q + +CV C G + C SLQAYA+LCAQ WRN T C + CP Y
Sbjct: 4711 QHYYDACVFDSCFMPGSSLE-CASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQ 4769
Query: 1820 PCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSC-VPLGQCGCTDPAGSYHP 1878
C TC S ++ ++ E C C +G + V + CGC P
Sbjct: 4770 ACGPAEEPTCKSSSSQQN---NTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPRE 4826
Query: 1879 VGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQI 1913
GE + E C + I C C +
Sbjct: 4827 FGEHF--EFDCKNCVCLEGGSGIICQPKRCSQKPV 4859
Score = 100 bits (250), Expect = 2e-20
Identities = 113/488 (23%), Positives = 184/488 (37%), Gaps = 68/488 (13%)
Query: 1892 LCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLP----------GESHYVS 1941
+ TC +N + + C+P + +GL R C G+ HYV+
Sbjct: 4432 MATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVT 4491
Query: 1942 FDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKH----EKEEGGTEAFRLHEVYIDIYD 1997
FDG +S CT VLV+ P++ I H +K HE +
Sbjct: 4492 FDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIK 4551
Query: 1998 AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNI-KIGVQVKFDGNHLLEIE 2056
+ +V +N + V LP G+ V S I +V+I ++GV V ++G +
Sbjct: 4552 TVHMMPMQVQVQVNRQAVALPYKKY--GLEVYQSGINYVVDIPELGVLVSYNGLS-FSVR 4608
Query: 2057 IPTTYYG-KVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKD-IDPSCQSLLVDE 2114
+P +G G CG + D+ ++PS E+ ++ + W D P C
Sbjct: 4609 LPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTT 4668
Query: 2115 QQ----IPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTL 2170
++ +P + P +C + L C+ ++ ++AQC + + + C
Sbjct: 4669 KRPAVTVPGGGKTTPHKDCTPSPL------CQ-LIKDSLFAQCHALVPPQHYYDACVFDS 4721
Query: 2171 CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSF--CPLECPAYSSYTNCLPSCSPSC 2228
C G C +LQA+ A C Q + WRN + C +ECP++ Y C P+ P+C
Sbjct: 4722 CFMPG-SSLECASLQAYAALCAQQNICLD-WRNHTHGACLVECPSHREYQACGPAEEPTC 4779
Query: 2229 WDLDGRCEGAKVPSACAEGCICQPG---YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVS 2285
+ + EGC C G Y D CV CGC G+ +
Sbjct: 4780 KSSSSQQNN----TVLVEGCFCPEGTMNYAPGFDVCV--KTCGCVGPDNVPREFGEHFEF 4833
Query: 2286 SGCTEKCVCT--GGAIQCGDFRC--------------------PSGSHCQLTSDNSNSNC 2323
+ CVC G I C RC P+ + C +T N++
Sbjct: 4834 D--CKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSL 4891
Query: 2324 VSDKSEQC 2331
+K C
Sbjct: 4892 CKEKPSVC 4899
Score = 84.0 bits (206), Expect = 2e-15
Identities = 69/257 (26%), Positives = 113/257 (43%), Gaps = 24/257 (9%)
Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIK----TVDVLPEGVEPLLVEGRNKMDPPRSSI 2386
C+ +GDP Y+TFDG Y QG TYVL++ +VD ++ + +K+ PR+ I
Sbjct: 4481 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 4540
Query: 2387 FLQE----VITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYL-VTDFE 2441
E +I TV+ +Q+Q + VN Q +A+PY+ L V G + + +
Sbjct: 4541 VRHETQEVLIKTVHMMPMQVQ----VQVNRQAVALPYK-KYGLEVYQSGINYVVDIPELG 4595
Query: 2442 LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKT 2501
++VS+ G +V + G CG +D +LPSG + N + W V
Sbjct: 4596 VLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLV-N 4654
Query: 2502 EDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACH 2561
+ + P + + G +C+P L C+++ D FA CH
Sbjct: 4655 DPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL-------CQLIKD--SLFAQCH 4705
Query: 2562 QTVAPEPFQEHCVLDLC 2578
V P+ + + CV D C
Sbjct: 4706 ALVPPQHYYDACVFDSC 4722
Score = 59.7 bits (143), Expect = 4e-08
Identities = 49/155 (31%), Positives = 62/155 (40%), Gaps = 13/155 (8%)
Query: 902 PTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPE-KLTIPTE 960
P +K +P PT + P PT T+P TT S T T PT +P +T T
Sbjct: 1391 PMDKCITTPSPPTTTPSPP--PTSTTTLP-PTTTPSPPTTTTTTPPPTTTPSPPITTTTT 1447
Query: 961 KPTISTEKPTIPTEKLTIPTEKPTIPTEKP----TIPTEKLTALRPPHPS-----PTATG 1011
P +T P I T PT P+ PT P T P+ T P P+ PT T
Sbjct: 1448 PPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507
Query: 1012 LAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPP 1046
+ + P T S TTTT +T PP
Sbjct: 1508 ITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPP 1542
>gi|239757284 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 593
Score = 297 bits (760), Expect = 1e-79
Identities = 182/547 (33%), Positives = 254/547 (46%), Gaps = 77/547 (14%)
Query: 1240 LPAIPSKGVFLGAS-GRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNS 1298
LP + + G + G V ++T+FGLRV +D + VTV Y ++CGLCGNY+G+
Sbjct: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
Query: 1299 DNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQ--------KYQVVNSPSCDSSLQSSMS 1350
+D K +GS AG+ E GNSW+ + D C + S C L+
Sbjct: 63 KDDFQKPNGSQAGNANEFGNSWE-EVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121
Query: 1351 GPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAG 1410
FCG L GP +C V C+ D+C G +LC+++ + CQ AG
Sbjct: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
Query: 1411 HAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSG 1470
V+PWR FCPM CPPNS Y LCA C C + + C D C E C+C+ GF+ +G
Sbjct: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG 241
Query: 1471 LECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDG 1530
C+P QCGC H G Y++ + C++ C C + + CQ C+ + C G
Sbjct: 242 QACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
Query: 1531 IYGC--------------HAQGAA-----------------------------TCTASG- 1546
I C +GAA TC G
Sbjct: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
Query: 1547 ----------------DPHYLTFDGALHHFMGTCTYVLTR---PCWSRSQDSYFVVSATN 1587
DPHY +FDG F GTC YVL P S + F V+ N
Sbjct: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
Query: 1588 ENRGGILEVSYIKAVHVTVFDLSISLLRG--CKVMLNGHRVALPVWLAQGRVTIRLSSNL 1645
+NRG VSY++ V V +IS+ + KV +NG ALPV +A GR+++ ++
Sbjct: 421 QNRGN-PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASK 479
Query: 1646 VLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQL 1705
LL +FGLQV YD + V+VT+PSSY G +CGLCGN + N +D + P+ LA
Sbjct: 480 ALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIW 539
Query: 1706 GAAWKLP 1712
G +W+ P
Sbjct: 540 GGSWRAP 546
Score = 266 bits (679), Expect = 3e-70
Identities = 162/558 (29%), Positives = 249/558 (44%), Gaps = 86/558 (15%)
Query: 1628 LPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNS 1687
LPV LA G++ + V++ T+FGL+V YD + V VTVP +Y Q+CGLCGNYN +
Sbjct: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
Query: 1688 LDDNLRPDRKLAGDSMQLGAAWK--LPES-------SEPG---CFLVGGKPSSCQENSMA 1735
DD +P+ AG++ + G +W+ +P+S PG C P ++
Sbjct: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQK 122
Query: 1736 DAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLC-A 1794
+ + C +L +P GP S CH++V PQ C+ C G+ + LC ++ AY S C A
Sbjct: 123 EEF---CGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
Query: 1795 QAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGH 1854
G WR TFCPM CPP S Y C+ C CS+++ P C CAE C+C G
Sbjct: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG--CAEGCQCDSGF 237
Query: 1855 ILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQIC 1914
+ +G +CVP+ QCGC Y P E+ + C + CTC + C + +CKP Q+C
Sbjct: 238 LYNGQACVPIQQCGCYHNGVYYEP--EQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVC 295
Query: 1915 WALDGLLRC--------------------------------------------------- 1923
G+L C
Sbjct: 296 QPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETC 355
Query: 1924 -RASGVGVC--------QLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMA---LPFFK 1971
G GVC L G+ HY SFDG C VL P ++ L F
Sbjct: 356 KEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 415
Query: 1972 ISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPAISQIPGVSVK 2029
++ K++ G + V + +++ K +V +N LP +SV
Sbjct: 416 VTTKNQ-NRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVT 474
Query: 2030 SSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVAN 2089
+ +++ G+QV +D N +++ +P++Y+G VCG+CGN + ++ + P+ +A
Sbjct: 475 QGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAP 534
Query: 2090 SDSEFVNSWKDKDIDPSC 2107
S + SW+ DP C
Sbjct: 535 SIPIWGGSWRAPGWDPLC 552
Score = 202 bits (515), Expect = 3e-51
Identities = 148/541 (27%), Positives = 223/541 (41%), Gaps = 82/541 (15%)
Query: 2036 IVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFV 2095
++ G++V +D + + + +P YY ++CG+CGN+N + +D+ P+ A + +EF
Sbjct: 22 VIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG 81
Query: 2096 NSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCE--AALRAPVW--A 2151
NSW++ D C L P + PS C +L + +K E L +P +
Sbjct: 82 NSWEEVVPDSPC---LPPTPCPPGSEDCIPSHKC-PPELEKKYQKEEFCGLLSSPTGPLS 137
Query: 2152 QCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLEC 2211
C +D L DC LC GG LC + A+ + CQ+ G WR +FCP+EC
Sbjct: 138 SCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC 197
Query: 2212 PAYSSYTNCLPSCSPSCWDLDG--RCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGC 2269
P S Y C +CS C L +C+ CAEGC C G++ + CVP QCGC
Sbjct: 198 PPNSHYELCADTCSLGCSALSAPPQCQ-----DGCAEGCQCDSGFLYNGQACVPIQQCGC 252
Query: 2270 KD---------------------AHGGSIPL--------GKSWVSSGCTEKCVCT----- 2295
H G + + G+ SG CV
Sbjct: 253 YHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRS 312
Query: 2296 ---------GGAI-----------------QCGDFRCPSGSHCQLTSDNSNSNCVSDKSE 2329
G AI C C C+ C+ +
Sbjct: 313 LAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCK--EQGGQGVCLPNYEA 370
Query: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMDPPRSSIF 2387
C ++GDP Y +FDG + QG YVL T V +G+ P V +N+ + +
Sbjct: 371 TCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSY 430
Query: 2388 LQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE-HLRVTLWGQRLYLVTDFELVV 2444
++ V G + + ++ VN A+P + + VT + LV DF L V
Sbjct: 431 VRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQV 490
Query: 2445 SFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDA 2504
S+ ++LPS Y G V GLCGN D+N ND + P+G L ++ +G SW D
Sbjct: 491 SYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDP 550
Query: 2505 L 2505
L
Sbjct: 551 L 551
Score = 151 bits (382), Expect = 8e-36
Identities = 112/352 (31%), Positives = 149/352 (42%), Gaps = 78/352 (22%)
Query: 1044 CPPNARYESCA--CPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
CPPN+ YE CA C C S P C C EGC C+ GFL++ C+ C C++N
Sbjct: 197 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 256
Query: 1100 DYYEPGAEWFSPN--------------CTEHCRCWPGSRVE------------------- 1126
YYEP N C EH C PG +
Sbjct: 257 VYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHS-CKPGQVCQPSGGILSCVTKVTLRSLAQ 315
Query: 1127 ----------------------------CQISQCGTHTVCQLKNGQYGCHPYAGTATCLV 1158
C C C+ + GQ C P ATC +
Sbjct: 316 TGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNY-EATCWL 374
Query: 1159 YGDPHYVTFDGRHFGFMGKCTYILAQP-C-GNSTDPF--FRVTAKNEEQGQEGVSCLSKV 1214
+GDPHY +FDGR F F G C Y+LA C G ST F VT KN+ +G VS + V
Sbjct: 375 WGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVV 434
Query: 1215 YVTLPESTVTLLKGR--RTLVGGQQVTLPAIPSKG---VFLGASGRFVELQTEFGLRVRW 1269
V + +++ K + V G LP + G V GAS L +FGL+V +
Sbjct: 435 TVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKAL--LVADFGLQVSY 492
Query: 1270 DGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQ 1321
D + ++ VT+ S+Y G +CGLCGN D N +ND + +G+ A G SW+
Sbjct: 493 DWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 544
Score = 119 bits (297), Expect = 6e-26
Identities = 83/304 (27%), Positives = 130/304 (42%), Gaps = 45/304 (14%)
Query: 2422 NEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMML 2481
N +R + G + + TDF L V++ +++P Y + GLCGNY+ + K+D
Sbjct: 9 NGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQK 68
Query: 2482 PSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLA 2540
P+G+ N N FGNSWE D+ P P G + +C PE +
Sbjct: 69 PNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPP---------GSEDCIPSHKCPPELEKK 119
Query: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQ-------DPREQEELRCQV 2593
+ C +L+ P GP ++CH+ V P+ + C+ DLC CQ
Sbjct: 120 YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
Query: 2594 LSGHGVSSR------------YHISELYDTLP---SIL-----CQPGRPRGLRGPLRGRL 2633
GH R H DT S L CQ G G +
Sbjct: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQ--CDSGF 237
Query: 2634 RQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSCRA 2693
+ + C+ P+ CGC NG+YY+ + L ++C Q+CTC + ++++C+ SC+
Sbjct: 238 LYNGQACV------PIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKP 291
Query: 2694 GEVC 2697
G+VC
Sbjct: 292 GQVC 295
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 290 bits (743), Expect = 1e-77
Identities = 222/801 (27%), Positives = 329/801 (41%), Gaps = 88/801 (10%)
Query: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQ 1205
G + TA C ++G TFDG + F G C+Y+LA C + F + Q
Sbjct: 25 GTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS---FSIIG----DFQ 77
Query: 1206 EGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTE-FG 1264
G VY+ + G T G Q+V++P SKG++L + +L E +G
Sbjct: 78 NGKRVSLSVYLGEFFDIHLFVNGTVTQ-GDQRVSMP-YASKGLYLETEAGYYKLSGEAYG 135
Query: 1265 LRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQ 1324
R DG V +S Y K CGLCGN++ +++D + +G+ D + NSW
Sbjct: 136 FVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSS 195
Query: 1325 DEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLD 1384
E Q C++ +S SC+ S G +L+ + F C V F C
Sbjct: 196 GE-QWCERASPPSS-SCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKT 253
Query: 1385 MCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH 1444
+C G C + TC G + W + C CP +Y C PC TC
Sbjct: 254 LCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQ 313
Query: 1445 SGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCK--- 1501
S C +RCV+ C C G +L C+ ++C C+H G+R Y PG
Sbjct: 314 SLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHS-------GKR-YPPGTSLSR 365
Query: 1502 --ELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHH 1559
C+C ++ W C +E G+ C +G H+ +FD
Sbjct: 366 DCNTCICRNSQ------WICSNEECPGE--------------CLVTGQSHFKSFDNRYFT 405
Query: 1560 FMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLR---G 1616
F G C Y+L R C QD F + + ++V V + L SL++ G
Sbjct: 406 FSGICQYLLARDC----QDHSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHG 461
Query: 1617 CKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQL 1676
V ++G V LP+ R+ +++++ L Y LQ+ +DG + V + Y G+
Sbjct: 462 AGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGE-DLQMDWDGRGRLLVKLSPVYAGKT 520
Query: 1677 CGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMAD 1736
CGLCGNYN N DD L P G AWKL + L C N
Sbjct: 521 CGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQD---LQKQHSDPCALNPRMT 577
Query: 1737 AWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQ 1795
+++ CA+L +P F CH+ V P +C + C LC +L +YA+ CA
Sbjct: 578 RFSEEACAVLTSP--TFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAG 635
Query: 1796 AGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNP-RDCPKALPCAESCECQKG- 1853
G AWR C + CP G Y C +PC TC S++ P +C +A C E C C G
Sbjct: 636 RGVRVAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEA--CLEGCFCPPGL 693
Query: 1854 HILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQI 1913
++ CVP QC C + P E ++++ + +
Sbjct: 694 YMDERGDCVPKAQCPCYYDGEIFQP--EDIFSDH-----------------------HTM 728
Query: 1914 CWALDGLLRCRASGVGVCQLP 1934
C+ DG + C SGV LP
Sbjct: 729 CYCEDGFMHCTMSGVPGSLLP 749
Score = 263 bits (673), Expect = 1e-69
Identities = 210/777 (27%), Positives = 324/777 (41%), Gaps = 86/777 (11%)
Query: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYI 1599
A C+ G TFDG+++ F G C+Y+L C RS S + + G
Sbjct: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS------FSIIGDFQNG------- 79
Query: 1600 KAVHVTVF---DLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQV 1656
K V ++V+ I L V RV++P + ++G + L +G
Sbjct: 80 KRVSLSVYLGEFFDIHLFVNGTVTQGDQRVSMP-YASKGLYLETEAGYYKLSGEAYGFVA 138
Query: 1657 RYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSE 1716
R DGS +V + Y + CGLCGN+N + DD + + L D +W L S E
Sbjct: 139 RIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWAL-SSGE 197
Query: 1717 PGCFLVGGKPSSCQENS--MADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG 1774
C SSC +S M + C +L F++CH +V P+ A C C
Sbjct: 198 QWCERASPPSSSCNISSGEMQKGLWEQCQLL-KSTSVFARCHPLVDPEPFVALCEKTLCE 256
Query: 1775 TKGDTTALCRSLQAYASLCAQAGQAP-AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSIN 1833
G C +L YA CAQ G W + + C CP G Y C SPC TC S++
Sbjct: 257 CAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLH 316
Query: 1834 NPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLC 1893
C + C + C C +G +L CV +C C G+R+ + +R C
Sbjct: 317 INEMCQER--CVDGCSCPEGQLLDEGLCVESTECPCVHS-------GKRYPPGTSLSRDC 367
Query: 1894 -TCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
TC N+ Q C N+ C G C + G+SH+ SFD +
Sbjct: 368 NTCICRNS----QWICS-NEEC-------------PGECLVTGQSHFKSFDNRYFTFSGI 409
Query: 1953 CTLVLVKVCHP-AMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLIN 2011
C +L + C + ++ + +++ T + + ++++ V L+ G V ++
Sbjct: 410 CQYLLARDCQDHSFSIVIETVQCADDRDAVCTRSVTVR--LPGLHNSLVKLKHGAGVAMD 467
Query: 2012 SKQVTLPAISQIPGVSVKSSSIYSIVNIKIG--VQVKFDGNHLLEIEIPTTYYGKVCGMC 2069
+ V LP + G ++ + V + G +Q+ +DG L +++ Y GK CG+C
Sbjct: 468 GQDVQLPLLK---GDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLC 524
Query: 2070 GNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNC 2129
GN+N + D+ + PS +F N+WK + CQ L Q+ S C
Sbjct: 525 GNYNGNQGDDFLTPSGLAEPRVEDFGNAWK---LHGDCQDL-----------QKQHSDPC 570
Query: 2130 RAAD-LRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFG 2188
+ R E+ A L +P + C + P+L +C +C + LC AL ++
Sbjct: 571 ALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYA 630
Query: 2189 ATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDL---DGRCEGAKVPSACA 2245
A C +G++ WR C L CP Y C C+ +C L D C AC
Sbjct: 631 AACAGRGVR-VAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECN-----EACL 684
Query: 2246 EGCICQPGYVLSE-DKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQC 2301
EGC C PG + E CVP++QC C + G I + S T C C G + C
Sbjct: 685 EGCFCPPGLYMDERGDCVPKAQCPC--YYDGEIFQPEDIFSDHHT-MCYCEDGFMHC 738
Score = 214 bits (546), Expect = 7e-55
Identities = 197/830 (23%), Positives = 323/830 (38%), Gaps = 141/830 (16%)
Query: 1926 SGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEA 1985
S C L G +FDGS +S C+ +L C F I + + + +
Sbjct: 30 SSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS----FSIIGDFQNGKRVSLS 85
Query: 1986 FRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSS-IYSIVNIKIGVQ 2044
L E + DI+ L V ++V++P S+ G+ +++ + Y + G
Sbjct: 86 VYLGE-FFDIH-----LFVNGTVTQGDQRVSMPYASK--GLYLETEAGYYKLSGEAYGFV 137
Query: 2045 VKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID 2104
+ DG+ ++ + Y+ K CG+CGNFN ED+ M + + +F NSW +
Sbjct: 138 ARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197
Query: 2105 PSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAR---EKCEAALRAPVWAQCASRIDLTP 2161
C E+ PS +C + + E+C+ V+A+C +D P
Sbjct: 198 QWC------------ERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEP 245
Query: 2162 FLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCL 2221
F+ C TLCE G + C AL + TC +G+ W + S C CPA Y C+
Sbjct: 246 FVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCV 305
Query: 2222 PSCSPSCWDL--DGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPL 2279
C+ +C L + C+ C +GC C G +L E CV ++C C + G P
Sbjct: 306 SPCARTCQSLHINEMCQ-----ERCVDGCSCPEGQLLDEGLCVESTECPCVHS-GKRYPP 359
Query: 2280 GKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRY 2339
G S +S C C+C C + CP +C V G +
Sbjct: 360 GTS-LSRDC-NTCICRNSQWICSNEECPG---------------------ECLVTGQSHF 396
Query: 2340 LTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYK 2399
+FD + G Y+L + + +++E D R ++ + V + G
Sbjct: 397 KSFDNRYFTFSGICQYLLARDCQ---DHSFSIVIETVQCAD-DRDAVCTRSVTVRLPGLH 452
Query: 2400 ---VQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISL 2456
V+L+ G + ++ Q + +P + + L +L + + GR ++ L
Sbjct: 453 NSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKL 512
Query: 2457 PSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEE 2516
+Y G GLCGNY+ N+ +D + PSG + FGN+W++ + L+ + P
Sbjct: 513 SPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPC-- 570
Query: 2517 EGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLD 2576
++ S +AC VL P F ACH+ V+P P+ +C D
Sbjct: 571 -----------------ALNPRMTRFSEEACAVLTSP--TFEACHRAVSPLPYLRNCRYD 611
Query: 2577 LCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQH 2636
+CS D R E C L+ + + RG+R
Sbjct: 612 VCSCSDGR---ECLCGALASYAAAC-------------------AGRGVR---------- 639
Query: 2637 PRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEV 2696
+ W EP + C +Y Q G+ C+ C S C +C G
Sbjct: 640 ----VAWR-EPGRCELNCPKGQVYLQCGT-----PCNLTCRSLSYPDEECNE-ACLEGCF 688
Query: 2697 CTLG---NHTQGCFPESPCLQNPCQNDGQCREQGATFT-----CECEVGY 2738
C G + C P++ C PC DG+ + F+ C CE G+
Sbjct: 689 CPPGLYMDERGDCVPKAQC---PCYYDGEIFQPEDIFSDHHTMCYCEDGF 735
Score = 208 bits (529), Expect = 7e-53
Identities = 144/506 (28%), Positives = 209/506 (41%), Gaps = 45/506 (8%)
Query: 990 PTIPTEKLTALRPPHPSPTATGL--AALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPN 1047
P + E AL A GL A + +A + ++L T + + CP
Sbjct: 239 PLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAG 298
Query: 1048 ARYESCA--CPASCKSPRPS--CGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYE 1103
Y C C +C+S + C C +GC C G L + C++++ C C ++ Y
Sbjct: 299 MEYRQCVSPCARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYP 358
Query: 1104 PGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPH 1163
PG S +C C +N Q+ C CLV G H
Sbjct: 359 PGTS-LSRDCN----------------------TCICRNSQWICSNEECPGECLVTGQSH 395
Query: 1164 YVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQE-GVSCLSKVYVTLP--- 1219
+ +FD R+F F G C Y+LA+ C D F + + + + C V V LP
Sbjct: 396 FKSFDNRYFTFSGICQYLLARDC---QDHSFSIVIETVQCADDRDAVCTRSVTVRLPGLH 452
Query: 1220 ESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTV 1279
S V L G + GQ V LP + V L L++ WDG +L V +
Sbjct: 453 NSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKL 512
Query: 1280 SSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSP 1339
S Y+GK CGLCGNY+GN +D L G E+ GN+W+ D CQ Q +S
Sbjct: 513 SPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGD----CQDLQKQHSD 568
Query: 1340 SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHM 1399
C + + + C L T FE C V + +C D+C + LC +
Sbjct: 569 PCALNPRMTRFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGAL 626
Query: 1400 STMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHS-GFSGMFCSDRCVE 1458
++ C G V WREP C + CP Y C PC TC S + C++ C+E
Sbjct: 627 ASYAAACAGRGVRV-AWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLE 685
Query: 1459 ACECNPGFVLSGL-ECIPRSQCGCLH 1483
C C PG + +C+P++QC C +
Sbjct: 686 GCFCPPGLYMDERGDCVPKAQCPCYY 711
Score = 175 bits (444), Expect = 5e-43
Identities = 125/470 (26%), Positives = 189/470 (40%), Gaps = 53/470 (11%)
Query: 1044 CPP-NARYESCACPASCKSPRPSCGPL-CREGCVCNPGFLFSDNHCIQASSCNCFYNNDY 1101
CP N R E C +C++ C + C GC+C PG + +N C+ C CF+
Sbjct: 776 CPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKE 835
Query: 1102 YEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGD 1161
Y PG + + G +T C ++ ++ C + ATC G
Sbjct: 836 YAPG----------------------ETVKIGCNT-CVCRDRKWNCTDHVCDATCSTIGM 872
Query: 1162 PHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPES 1221
HY+TFDG + F G+C Y+L Q S FR+ N+ V C +V + +
Sbjct: 873 AHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKKRVTILVEGG 932
Query: 1222 TVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSS 1281
+ L G V P + SGR++ L L V WD + V +
Sbjct: 933 EIELFDGE------VNVKRPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQ 986
Query: 1282 TYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSP-S 1340
TY K+CGLCGN+DG +ND + D + GNSW+ + + +K + +SP +
Sbjct: 987 TYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV-SSQCADTRKVPLDSSPAT 1045
Query: 1341 CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQH--LLCTH 1398
C +++ C L T F+ C V + D C+ D C + + C
Sbjct: 1046 CHNNIMKQTMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDT 1103
Query: 1399 MSTMTTTCQDAGHAVKPWREPHFCPMACPPNS----------KYSLCAKPCPDTCHSGFS 1448
++ C G V WR CP +C + +Y+ CA C TC
Sbjct: 1104 IAAYAHVCAQHGKVV-TWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHP-E 1161
Query: 1449 GMFCSDRCVEAC--ECNPGFVLSGL--ECIPRSQCGCLHPAGSYFKVGER 1494
+ C +CVE C C PG +L L C+ C AG F G++
Sbjct: 1162 PLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKK 1211
Score = 150 bits (378), Expect = 2e-35
Identities = 130/515 (25%), Positives = 209/515 (40%), Gaps = 79/515 (15%)
Query: 1419 PHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQ 1478
P + CP ++ + + C TC + + S CV C C PG V C+ +
Sbjct: 769 PPMVKLVCPADNLRAEGLE-CTKTCQN-YDLECMSMGCVSGCLCPPGMVRHENRCVALER 826
Query: 1479 CGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQG 1538
C C H G + GE K GC CVC R + W C C
Sbjct: 827 CPCFHQ-GKEYAPGET-VKIGCNT-CVC------RDRKWNC-TDHVCD------------ 864
Query: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVV---------SATNEN 1589
ATC+ G HYLTFDG + F G C YVL + + ++ ++ S +
Sbjct: 865 -ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKK 923
Query: 1590 RGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLY 1649
R IL ++ + +FD +++ R K + + S ++L
Sbjct: 924 RVTIL----VEGGEIELFDGEVNVKRPMK--------------DETHFEVVESGRYIILL 965
Query: 1650 TNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW 1709
L V +D + V + +Y ++CGLCGN++ +D + ++ D + G +W
Sbjct: 966 LGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSW 1025
Query: 1710 KLP-ESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFAS 1767
K+ + ++ + P++C N M + +C IL + F C+++V P+
Sbjct: 1026 KVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDV--FQDCNKLVDPEPYLDV 1083
Query: 1768 CVHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGS--------- 1816
C++ C + GD C ++ AYA +CAQ G+ WR T CP C +
Sbjct: 1084 CIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECE 1143
Query: 1817 -SYSPCSSPCPDTCSSINNPRDCPKALPCAESC--ECQKGHILSG--TSCVPLGQCGCTD 1871
Y+ C+ C TC P CP + C E C C G IL +CV C +
Sbjct: 1144 WRYNSCAPACQVTCQH-PEPLACP--VQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCE 1200
Query: 1872 PAGSYHPVGERWY---TENTCTRLCTCSVHNNITC 1903
AG G++ ++ ++C C V N+TC
Sbjct: 1201 VAGRRFASGKKVTLNPSDPEHCQICHCDV-VNLTC 1234
Score = 127 bits (320), Expect = 1e-28
Identities = 105/445 (23%), Positives = 176/445 (39%), Gaps = 44/445 (9%)
Query: 1481 CLHPAGSYFKVGERWYKPGCKELCVCE-------SNNRIRCQPW---RCRAQEFCGQQDG 1530
C+ G+ + G+ W P C+ ++R+ C C + + +
Sbjct: 1879 CMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEE 1938
Query: 1531 IYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENR 1590
GC CT S H +TFDG G+C+YVL + ++ QD ++ +
Sbjct: 1939 TCGCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ---NKEQDLEVILHNGACSP 1995
Query: 1591 GGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYT 1650
G +K++ V LS+ L +V +NG V++P V + + + +
Sbjct: 1996 GA--RQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFN 2053
Query: 1651 NFGLQVRY--DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708
+ G + + P ++ + GLCG + N +D + D + D L
Sbjct: 2054 HLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQE 2113
Query: 1709 WKLPESSEPGCFLVGGKPSSCQ---ENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSF 1765
W + PG +CQ E + +C +L+ P F++CH+V+ P + +
Sbjct: 2114 WTV---QRPG--------QTCQPILEEQCLVPDSSHCQVLLLPL--FAECHKVLAPATFY 2160
Query: 1766 ASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPC 1825
A C C + +C + +YA LC G WR FC M CPP Y+ C C
Sbjct: 2161 AICQQDSCHQE----QVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGC 2216
Query: 1826 PDTC-SSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC-GCTDPAGSYHPVGERW 1883
P C ++++ D P +E C C ++ SCVP C C G H E W
Sbjct: 2217 PRHCDGNVSSCGDHP-----SEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAW 2271
Query: 1884 YTENTCTRLCTCSVHNNITCFQSTC 1908
++ ++CTC + C C
Sbjct: 2272 VPDHQPCQICTCLSGRKVNCTTQPC 2296
Score = 115 bits (288), Expect = 6e-25
Identities = 137/565 (24%), Positives = 206/565 (36%), Gaps = 82/565 (14%)
Query: 2192 QSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQ 2251
+S +PP+ + L CPA + L C+ +C + D C + C GC+C
Sbjct: 763 RSLSCRPPMVK------LVCPADNLRAEGL-ECTKTCQNYDLEC----MSMGCVSGCLCP 811
Query: 2252 PGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSH 2311
PG V E++CV +C C H G V GC CVC C D C +
Sbjct: 812 PGMVRHENRCVALERCPC--FHQGKEYAPGETVKIGCNT-CVCRDRKWNCTDHVCDA--- 865
Query: 2312 CQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPL 2371
CS G YLTFDG Y G YVL++ G +
Sbjct: 866 ------------------TCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRI 907
Query: 2372 LVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWG 2431
LV + P S + V V G +++L G VN ++ P + H V G
Sbjct: 908 LVGNKGCSHP--SVKCKKRVTILVEGGEIELFDG---EVNVKR---PMKDETHFEVVESG 959
Query: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491
+ + L+ L V + + + L Y+ V GLCGN+D + ND+ + + ++
Sbjct: 960 RYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPV 1019
Query: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLA 2551
FGNSW+V ++ A R +P + + V +CR+L
Sbjct: 1020 DFGNSWKVSSQCA---DTRKVPLDSSPATCHNNIMKQTMVD------------SSCRILT 1064
Query: 2552 DPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDT 2611
F C++ V PEP+ + C+ D CS + + C ++ + H +
Sbjct: 1065 --SDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDC-ACFCDTIAAYAHVCAQHGKVVTWR 1121
Query: 2612 LPSILCQPGRPRGLRG---PLRGRLRQHPRLC--LQWHPEPPLADCGCTSNGIYYQLGSS 2666
++ Q R LR R C HPEP C G +
Sbjct: 1122 TATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQCV-EGCHAHCPPG 1180
Query: 2667 FLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQCREQ 2726
+ ++ Q C +P C EV + +P CQ C
Sbjct: 1181 KILDELLQTCV---------DPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQ---ICHCD 1228
Query: 2727 GATFTCE-CEVGYGGGLCMEPRDAP 2750
TCE C+ GGL + P DAP
Sbjct: 1229 VVNLTCEACQ--EPGGLVVPPTDAP 1251
Score = 115 bits (288), Expect = 6e-25
Identities = 116/446 (26%), Positives = 161/446 (36%), Gaps = 68/446 (15%)
Query: 1104 PGAEWFSPNCTEHCRCWPGS-------RVECQISQCGTHTVCQLKNGQYGCHPYAG---T 1153
PG W P+ C P RV C G C G T
Sbjct: 1889 PGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDR---GLRPSCPNSQSPVKVEETCGCRWT 1945
Query: 1154 ATCLVYGDP--HYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCL 1211
C+ G H VTFDG++F G C+Y+L Q + A + Q C+
Sbjct: 1946 CPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEVILHNGACSPGARQ---GCM 2002
Query: 1212 SKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSK---GVF-----------LGASGRFV 1257
+ V +V L V G+ V++P + V+ LG F
Sbjct: 2003 KSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFT 2062
Query: 1258 ELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELG 1317
EF L++ T++ K GLCG D N ND + DG+ D + L
Sbjct: 2063 PQNNEFQLQLS-----------PKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLV 2111
Query: 1318 NSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASF 1377
W T Q Q CQ DSS + P F C + A+F
Sbjct: 2112 QEW-TVQRPGQTCQPILEEQCLVPDSSHCQVLLLPLFA-----------ECHKVLAPATF 2159
Query: 1378 FDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAK 1437
+ C D C Q +C +++ C+ G V WR P FC M+CPP+ Y+ C
Sbjct: 2160 YAICQQDSCH----QEQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPPSLVYNHCEH 2214
Query: 1438 PCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQC-GCLHPAGSYFKVGERW- 1495
CP C S C D E C C P V+ C+P C C+ G + E W
Sbjct: 2215 GCPRHCDGNVSS--CGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWV 2272
Query: 1496 --YKPGCKELCVCESNNRIRCQPWRC 1519
++P C ++C C S ++ C C
Sbjct: 2273 PDHQP-C-QICTCLSGRKVNCTTQPC 2296
Score = 110 bits (276), Expect = 1e-23
Identities = 112/487 (22%), Positives = 172/487 (35%), Gaps = 94/487 (19%)
Query: 1825 CPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWY 1884
C TC N +C ++ C C C G + CV L +C C Y P GE
Sbjct: 788 CTKTCQ--NYDLEC-MSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAP-GE--- 840
Query: 1885 TENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDG 1944
T C C C C C G +HY++FDG
Sbjct: 841 TVKIGCNTCVCR-DRKWNCTDHVCD-------------------ATCSTIGMAHYLTFDG 880
Query: 1945 SNHSIPDACTLVLVK-------------VCHPAMALPFFKISAKHEKEEGGTEAFRLHEV 1991
+ P C VLV+ V + + P K + G E
Sbjct: 881 LKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKKRVTILVEGGE------- 933
Query: 1992 YIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNH 2051
I+++D +V +++ + V S Y I+ + + V +D +
Sbjct: 934 -IELFDGEVNVKR--------------PMKDETHFEVVESGRYIILLLGKALSVVWDRHL 978
Query: 2052 LLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLL 2111
+ + + TY KVCG+CGNF+ + ++L + +V +F NSWK S
Sbjct: 979 SISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWK-------VSSQC 1031
Query: 2112 VDEQQIPAEQQENPSGNCRAADLRRAR-EKCEAALRAPVWAQCASRIDLTPFLVDCA--N 2168
D +++P ++ C +++ + L + V+ C +D P+L C
Sbjct: 1032 ADTRKVPL---DSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDT 1088
Query: 2169 TLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS----------SYT 2218
CE G C + A+ C G K WR ++ CP C + Y
Sbjct: 1089 CSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEWRYN 1147
Query: 2219 NCLPSCSPSCWDLDGRCEGAKVPSACAEGC--ICQPGYVLSE--DKCVPRSQCGCKDAHG 2274
+C P+C +C E P C EGC C PG +L E CV C + G
Sbjct: 1148 SCAPACQVTC----QHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAG 1203
Query: 2275 GSIPLGK 2281
GK
Sbjct: 1204 RRFASGK 1210
Score = 103 bits (258), Expect = 2e-21
Identities = 98/458 (21%), Positives = 177/458 (38%), Gaps = 56/458 (12%)
Query: 1869 CTDPAGSYHPVGERWYTENTC-TRLC-----TCSVHNNITC---FQSTCKPNQICWALDG 1919
C D G+ G+ W + C T C T + + C + +C +Q ++
Sbjct: 1879 CMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEE 1938
Query: 1920 LLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKE 1979
CR + VC H V+FDG N + +C+ VL + + + +
Sbjct: 1939 TCGCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEVILHNGACSPGAR 1998
Query: 1980 EGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNI 2039
+G ++ + + V L V +N + V++P + V+V + ++ +
Sbjct: 1999 QGCMKSIEVKHSALS-----VELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFN 2053
Query: 2040 KIGVQVKFDG-NHLLEIEI-PTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
+G F N+ ++++ P T+ K G+CG ++ ++ M+ V V
Sbjct: 2054 HLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQE 2113
Query: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRI 2157
W + +CQ +L ++ +P S +C+ L P++A+C +
Sbjct: 2114 WTVQRPGQTCQPILEEQCLVP------DSSHCQ-------------VLLLPLFAECHKVL 2154
Query: 2158 DLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSY 2217
F C C + +C+ + ++ C++ G+ WR FC + CP Y
Sbjct: 2155 APATFYAICQQDSCH----QEQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPPSLVY 2209
Query: 2218 TNCLPSCSPSCWDLDGRCEGAKVPSAC----AEGCICQPGYVLSEDKCVPRSQC-GCKDA 2272
+C C C DG S+C +EGC C P V+ E CVP C C
Sbjct: 2210 NHCEHGCPRHC---DGNV------SSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGE 2260
Query: 2273 HGGSIPLGKSWV-SSGCTEKCVC-TGGAIQCGDFRCPS 2308
G ++WV + C C +G + C CP+
Sbjct: 2261 DGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPT 2298
Score = 88.2 bits (217), Expect = 1e-16
Identities = 112/472 (23%), Positives = 177/472 (37%), Gaps = 87/472 (18%)
Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
C+ +TFDG +++L G +YVL + + + +E +L G P ++
Sbjct: 1950 CTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKE---QDLEVILHNGA--CSPGARQGCMKS 2004
Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFEL--VVSFGG 2448
+ V+L + +E+ VN + ++VPY ++ V ++G ++ V L + +F
Sbjct: 2005 IEVKHSALSVELHSDMEVTVNGRLVSVPY-VGGNMEVNVYGAIMHEVRFNHLGHIFTFTP 2063
Query: 2449 RKNAV-ISL-PSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALL 2506
+ N + L P + GLCG D+N ND ML G +T + T W V+
Sbjct: 2064 QNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQ------ 2117
Query: 2507 RFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAP 2566
R G EQ + C+VL P FA CH+ +AP
Sbjct: 2118 -------------------RPGQTCQPILEEQCLVPDSSHCQVLLLPL--FAECHKVLAP 2156
Query: 2567 EPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISEL--YDTLPSIL---CQPGR 2621
F C D C + E + +GV + + PS++ C+ G
Sbjct: 2157 ATFYAICQQDSCHQEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGC 2216
Query: 2622 PRGLRG--------PLRGRLRQHPRLCLQWHPEPPLADCGCT-SNGIYYQLGSSFLTE-D 2671
PR G P G ++ L+ P A C +G+ +Q +++ +
Sbjct: 2217 PRHCDGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQ 2276
Query: 2672 CSQRCTCASSRILLCEPFSCRAG--------EVCTLGNHTQGCFPESPCLQNP------- 2716
Q CTC S R + C C EV L + C PE C+ +P
Sbjct: 2277 PCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVSCDLPP 2336
Query: 2717 ---CQ--------NDGQCREQGATFTCECEVGYGGGLC--MEPRDAPPPRKP 2755
C+ N G+CR FTC C C + P PP R P
Sbjct: 2337 VPHCERGLQPTLTNPGECR---PNFTCACRKEE----CKRVSPPSCPPHRLP 2381
Score = 50.4 bits (119), Expect = 2e-05
Identities = 28/96 (29%), Positives = 38/96 (39%), Gaps = 5/96 (5%)
Query: 1044 CPPNARYESC--ACPASCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSC-NCFYNND 1100
CPP+ Y C CP C SCG EGC C P + + C+ +C C +
Sbjct: 2203 CPPSLVYNHCEHGCPRHCDGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDG 2262
Query: 1101 YYEPGAEWFSPN--CTEHCRCWPGSRVECQISQCGT 1134
E + P+ + C C G +V C C T
Sbjct: 2263 VQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPT 2298
Score = 49.7 bits (117), Expect = 4e-05
Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 8/85 (9%)
Query: 1044 CPPNARYESCACPAS--CKS---PRPSCGPLCREGCVCNPGFLFSDN-HCIQASSCNCFY 1097
CP Y C P + C+S P C C EGC C PG + C+ + C C+Y
Sbjct: 652 CPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYY 711
Query: 1098 NNDYYEPGAEWFSPNCTEHCRCWPG 1122
+ + ++P + FS + T C C G
Sbjct: 712 DGEIFQP-EDIFSDHHT-MCYCEDG 734
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 286 bits (732), Expect = 2e-76
Identities = 243/955 (25%), Positives = 392/955 (41%), Gaps = 112/955 (11%)
Query: 1419 PHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQ 1478
P CP+ PP ++ + + TC G+ G C++ +A G + +C + Q
Sbjct: 71 PGLCPIYKPPETRPAKWNRTVR-TCCPGWGGAHCTEALAKASP--EGHCFAMWQC--QLQ 125
Query: 1479 CGCLHP-AGSYFKV-----GERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIY 1532
G + AGS + G+ W+ + C S + Q G ++
Sbjct: 126 AGSANASAGSLEECCARPWGQSWWDGSSQACRSCSSRHLPGSASSPALLQPLAGAVGQLW 185
Query: 1533 GCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGG 1592
H + +ATC + HY TFDG +HF+G CTY+L + + DS + V T +R
Sbjct: 186 SQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLL-----AGAADSTWAVHLTPGDR-- 238
Query: 1593 ILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVAL-PVWLAQGRVTIRLSSNLVLLYTN 1651
+ + + V + ++ L++ V + G V WL G ++++ + ++L
Sbjct: 239 CPQPGHCQRVTMGPEEV---LIQAGNVSVKGQLVPEGQSWLLHG-LSLQWLGDWLVLSGG 294
Query: 1652 FGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKL 1711
G+ VR D + + ++V GQ GLCG YN DD + P LA + G +W+L
Sbjct: 295 LGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRL 354
Query: 1712 PESSEPGCFLVGGKPSSCQENSMADA----------WNKNCAILINPQGPFSQCHQVVPP 1761
P SE GC C + DA C L+ +GPF QCH V P
Sbjct: 355 P-GSESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLL--EGPFGQCHAQVSP 411
Query: 1762 QSSFASCVHGQC-------GTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPP 1814
+C+ C G +G A+C + +Y CA+ WR FC CP
Sbjct: 412 AEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPG 471
Query: 1815 GSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAG 1874
G YS C S CP +C ++ + C CEC +G +GT CVP C C
Sbjct: 472 GQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPC----- 526
Query: 1875 SYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRC-RASGVGVCQL 1933
+ +R+ +T +LC C DG C +A C +
Sbjct: 527 --YYCRQRYVPGDTVRQLC------------------NPCVCRDGRWHCAQALCPAECAV 566
Query: 1934 PGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFR-LHEVY 1992
G+ HY++FDG ++S + C ++ + K E G +A LH +
Sbjct: 567 GGDGHYLTFDGRSYSFWGG------QGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAIS 620
Query: 1993 IDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFD-GNH 2051
+ + D + L+ VL+N + V LP I G+SV+ +S ++ G QV + +
Sbjct: 621 VSLEDTHIQLRDSGAVLVNGQDVGLPWIG-AEGLSVRRASSAFLLLRWPGAQVLWGLSDP 679
Query: 2052 LLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLL 2111
+ I + + +V G+CG F ++D+ + P+ +V S + F + ++ +
Sbjct: 680 VAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQ-----------V 728
Query: 2112 VDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLC 2171
+ + P+E S + E A L + V+ +C +D PF + C +C
Sbjct: 729 AGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVC 788
Query: 2172 EFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDL 2231
LC L A+ C +G PP WRN + CP+ CP Y C P+C C
Sbjct: 789 GCDPGSDCLCPVLSAYARRCAQEGASPP-WRNQTLCPVMCPGGQEYRECAPACGQHC--- 844
Query: 2232 DGRCEGAKVPSACAEGCICQPGYVLS-EDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTE 2290
G+ E +C GC C G + E +CVP S C C+ P G + +
Sbjct: 845 -GKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAP-GSATMKE--CN 900
Query: 2291 KCVC-TGGAIQCGDFRCPSGSHCQ-----------LTSD--NSNSNCVSDKSEQC 2331
+C+C G C CPS + C LT D ++N +C + ++ C
Sbjct: 901 RCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGC 955
Score = 285 bits (730), Expect = 3e-76
Identities = 242/857 (28%), Positives = 346/857 (40%), Gaps = 107/857 (12%)
Query: 1143 GQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEE 1202
GQ +ATC + HY TFDGRH+ F+G+CTY+LA + D + V +
Sbjct: 182 GQLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLA----GAADSTWAVHLTPGD 237
Query: 1203 QGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTE 1262
+ + C VT+ V + G ++ G + G+ L G ++ L
Sbjct: 238 RCPQPGHCQR---VTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGG 294
Query: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322
G+ VR D + ++V G+ GLCG Y+G ++D ++ G A GNSW+
Sbjct: 295 LGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRL 354
Query: 1323 DQDED---------QECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVK 1373
E Q C ++++ L++ C +L++ GPF C V
Sbjct: 355 PGSESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQD--VCHQLLE--GPFGQCHAQVS 410
Query: 1374 AASFFDSCMLDMC-------GFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
A + ++C+ C G +G Q +C ++ C H WR+P FC C
Sbjct: 411 PAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARR-HIHIRWRKPGFCERLC 469
Query: 1427 PPNSKYSLCAKPCPDTCHSGFSGM--FCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
P YS C CP +C + G C + CV CEC G +G C+P + C C +
Sbjct: 470 PGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYY- 528
Query: 1485 AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGC-HAQGAATCT 1543
C++ V R C P CR DG + C A A C
Sbjct: 529 ---------------CRQRYVPGDTVRQLCNPCVCR--------DGRWHCAQALCPAECA 565
Query: 1544 ASGDPHYLTFDGALHHFMGT--CTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKA 1601
GD HYLTFDG + F G C Y L + + + Q + G S + A
Sbjct: 566 VGGDGHYLTFDGRSYSFWGGQGCRYSLVQD-YVKGQLLILL------EHGACDAGSCLHA 618
Query: 1602 VHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGS 1661
+ V++ D I L V++NG V LP W+ +++R +S+ LL G QV + S
Sbjct: 619 ISVSLEDTHIQLRDSGAVLVNGQDVGLP-WIGAEGLSVRRASSAFLLLRWPGAQVLWGLS 677
Query: 1662 HLVE-VTVPSSYGGQLCGLCGNYNNNSLDDNLRP----DRKLAGDSMQLGAAWKLPESSE 1716
V +T+ + Q+ GLCG + N DD L P + +A + + A K SE
Sbjct: 678 DPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSE 737
Query: 1717 PGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGT 1775
L S C +S A+ + CAIL + F +CH++V + + C+ CG
Sbjct: 738 DSALL-----SPCTTHSQRHAFAEAACAILHS--SVFQECHRLVDKEPFYLRCLAAVCGC 790
Query: 1776 KGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNP 1835
+ LC L AYA CAQ G +P WRN+T CP+ CP G Y C+ C C P
Sbjct: 791 DPGSDCLCPVLSAYARRCAQEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHC---GKP 847
Query: 1836 RDCPKALPCAESCECQKGHILSGT-SCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCT 1894
DC + C C C G + CVP C C A Y P T C R C
Sbjct: 848 EDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSA---TMKECNR-CI 903
Query: 1895 CSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIP---- 1950
C C C C R G C L +S +NHS P
Sbjct: 904 CQERGLWNCTARHCPSQAFC------PRELVYAPGACLLTCDS-----PSANHSCPAGST 952
Query: 1951 DACTLVLVKVCHPAMAL 1967
D C VC P L
Sbjct: 953 DGC------VCPPGTVL 963
Score = 264 bits (674), Expect = 1e-69
Identities = 246/949 (25%), Positives = 363/949 (38%), Gaps = 189/949 (19%)
Query: 1044 CPPNARYESCA--CPASCKS----PRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFY 1097
CP Y C CP SC++ SC C GC C G ++ C+ A+ C C+Y
Sbjct: 469 CPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYY 528
Query: 1098 NNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCL 1157
Y PG T C P C ++G++ C A C
Sbjct: 529 CRQRYVPGD-------TVRQLCNP----------------CVCRDGRWHCAQALCPAECA 565
Query: 1158 VYGDPHYVTFDGRHFGFMG--KCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVY 1215
V GD HY+TFDGR + F G C Y L Q ++ E + SCL +
Sbjct: 566 VGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKG-----QLLILLEHGACDAGSCLHAIS 620
Query: 1216 VTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQL 1275
V+L ++ + L LV GQ V LP ++GA G V + L +RW G Q L
Sbjct: 621 VSLEDTHIQLRDSGAVLVNGQDVGLP-------WIGAEGLSVRRASSAFLLLRWPGAQVL 673
Query: 1276 --------YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDED 1327
Y+T+ ++ ++ GLCG + N +D L +PAGD E ++
Sbjct: 674 WGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFL----TPAGDVETSIAAF------- 722
Query: 1328 QECQKYQVVNS---PSCDSSLQSSMS--------GPGFCGRLVDTHGPFETCLLHVKAAS 1376
K+QV PS DS+L S + C L + F+ C V
Sbjct: 723 --ASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHSS--VFQECHRLVDKEP 778
Query: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436
F+ C+ +CG LC +S C G A PWR CP+ CP +Y CA
Sbjct: 779 FYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEG-ASPPWRNQTLCPVMCPGGQEYRECA 837
Query: 1437 KPCPDTCHSGFSGMFCSD--RCVEACECNPGFVLSGL-ECIPRSQCGCLHPAGSYFKVGE 1493
C C C + CV C C G + +C+P S C C ++G
Sbjct: 838 PACGQHCGKPED---CGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPC--------QLGA 886
Query: 1494 RWYKPGCKEL-----CVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAA--TCTASG 1546
R Y PG + C+C+ C C +Q FC ++ +A GA TC +
Sbjct: 887 RRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRE----LVYAPGACLLTCDSPS 942
Query: 1547 DPHYLTFDGALHHFMGTCTYVLTRPCW------SRSQDSYFVVSA--------------- 1585
H T +L C R +++ +A
Sbjct: 943 ANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQ 1002
Query: 1586 ---TNENRGGILEVSYIKAVHVTVFD-LSISLLRGCKVMLNGHRVALPVWLAQG------ 1635
T + R G + S A H FD L+ + C+ +L L AQ
Sbjct: 1003 WHCTGQRRSGRCQAS--GAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGAS 1060
Query: 1636 ------RVTIRLSSNLV------------------LLYTNFGLQVR-------------- 1657
+ +RL +V +YT GL +R
Sbjct: 1061 GLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGL 1120
Query: 1658 ---YDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGA-AWKLPE 1713
+DG V V + + G++ GLCG+++ ++ +D LR + + + +L A +W+L
Sbjct: 1121 TLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASND-LRSRQGVLEPTAELAAHSWRL-- 1177
Query: 1714 SSEPGCFLVGGKPSSCQENSMADAWNK-NCAILINPQGPFSQCHQVVPPQSSFASCVHGQ 1772
P C G P C N+ W + C L+ P F+ CH VPPQ + C++
Sbjct: 1178 --SPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPL--FTLCHAEVPPQQHYEWCLYDA 1233
Query: 1773 CG--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCS 1830
CG + GD LC ++ YA CA+ G WR++ C ++C G Y C CP TC
Sbjct: 1234 CGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEACGPTCPPTCH 1293
Query: 1831 SIN-NPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHP 1878
+ P + + C E C C +G +L G +C+ C C S+ P
Sbjct: 1294 EQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPP 1342
Score = 214 bits (545), Expect = 1e-54
Identities = 154/538 (28%), Positives = 219/538 (40%), Gaps = 72/538 (13%)
Query: 1044 CPPNARYESCACPASCKSPRP--SCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDY 1101
CP Y AC +C SP SC +GCVC PG + D C+ C C ++
Sbjct: 923 CPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSG-- 980
Query: 1102 YEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGD 1161
+W+ PN T C VC + Q+ C + C G
Sbjct: 981 -----QWYLPNATIQEDC----------------NVCVCRGRQWHCTGQRRSGRCQASGA 1019
Query: 1162 PHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPES 1221
PHYVTFDG F + G C Y+L + F V+A+N G G++C + V L +
Sbjct: 1020 PHYVTFDGLAFTYPGACEYLLVREASG----LFTVSAQNLPCGASGLTCTKALAVRLEGT 1075
Query: 1222 TVTLLKGRRTLVGGQQVTLPAI-PSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVS 1280
V +L+GR V G VT P + G+ L +G F+ L T GL + WDG ++ V +S
Sbjct: 1076 VVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLS 1135
Query: 1281 STYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPS 1340
+ G++ GLCG++DG++ ND G E +SW+ C + + P
Sbjct: 1136 PQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL----SPLCPEPGDLPHP- 1190
Query: 1341 CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ--GLQHLLCTH 1398
C + + CG L+ F C V ++ C+ D CG G LC+
Sbjct: 1191 CTMNTHRAGWARARCGALLQP--LFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSA 1248
Query: 1399 MSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF--SGMFCS-DR 1455
++T C GH V+ WR C + C Y C CP TCH G C
Sbjct: 1249 IATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVA 1307
Query: 1456 CVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVG--------ERWYKPG--- 1499
CVE C C G +L G C+ + C C P GS + +W+ G
Sbjct: 1308 CVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGG 1367
Query: 1500 -CKEL--------CVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHA----QGAATCTA 1544
C+EL +C+ N W C Q+ CG GC A +G TC++
Sbjct: 1368 HCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCGEGQMTCSS 1425
Score = 166 bits (420), Expect = 3e-40
Identities = 152/603 (25%), Positives = 234/603 (38%), Gaps = 76/603 (12%)
Query: 1717 PGCFLVGGKPSSCQE-NSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGT 1775
P C GKP C E S N +L +P+G Q VPP S C Q G
Sbjct: 838 PACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEG------QCVPP--SLCPC---QLGA 886
Query: 1776 KGDTTALCRSLQAYASLCAQAGQAPAWR-NRTFCPMR--CPPGSSYSPCSSPCPDTCSSI 1832
+ + +C + G W CP + CP Y+P C TC S
Sbjct: 887 RRYAPGSATMKECNRCICQERG---LWNCTARHCPSQAFCPRELVYAP--GACLLTCDSP 941
Query: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
+ CP + C C G +L CVP C C +WY N +
Sbjct: 942 SANHSCPAG--STDGCVCPPGTVLLDERCVPPDLCPCRHSG--------QWYLPNATIQE 991
Query: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
C C+ Q W G R G CQ G HYV+FDG + P A
Sbjct: 992 ---------DCNVCVCRGRQ--WHCTGQRRS-----GRCQASGAPHYVTFDGLAFTYPGA 1035
Query: 1953 CTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINS 2012
C +LV+ A F +SA++ G + + + + V + +G V +N
Sbjct: 1036 CEYLLVRE-----ASGLFTVSAQN-LPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNG 1089
Query: 2013 KQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNF 2072
VT P + PG+S++ + ++ +++ +G+ + +DG + +++ + G+V G+CG+F
Sbjct: 1090 VSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDF 1149
Query: 2073 NDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAA 2132
+ + ++L + + +SW+ + P C P + + N A
Sbjct: 1150 DGDASNDLRSRQGVLEPTAELAAHSWR---LSPLCPE--------PGDLPHPCTMNTHRA 1198
Query: 2133 DLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGAT 2190
RAR C A L+ P++ C + + C C+ GG + LC A+ +
Sbjct: 1199 GWARAR--CGALLQ-PLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADE 1255
Query: 2191 CQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCIC 2250
C G WR+ C L+C Y C P+C P+C + AC EGC C
Sbjct: 1256 CARHG-HHVRWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFC 1314
Query: 2251 QPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGS 2310
G +L C+ + C C+ S P G S + C C C G CG G
Sbjct: 1315 PEGTLLHGGACLEPASCPCEWGR-NSFPPG-SVLQKDC-GNCTCQEGQWHCGG----DGG 1367
Query: 2311 HCQ 2313
HC+
Sbjct: 1368 HCE 1370
Score = 163 bits (413), Expect = 2e-39
Identities = 223/994 (22%), Positives = 361/994 (36%), Gaps = 138/994 (13%)
Query: 1808 CPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC 1867
CP+ PP + + + C C +AL A +GH + C L
Sbjct: 74 CPIYKPPETRPAKWNRTVRTCCPGWGGAH-CTEALAKASP----EGHCFAMWQC-QLQAG 127
Query: 1868 GCTDPAGSYH-----PVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922
AGS P G+ W+ + + +CS + S + A+ L
Sbjct: 128 SANASAGSLEECCARPWGQSWW-DGSSQACRSCSSRHLPGSASSPALLQPLAGAVGQLWS 186
Query: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982
C HY +FDG ++ CT +L A+ ++ + G
Sbjct: 187 QHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAV---HLTPGDRCPQPG 243
Query: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042
H + + +V +Q G+ V + + V + G+S++ + +++ +G
Sbjct: 244 ------HCQRVTMGPEEVLIQAGN-VSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLG 296
Query: 2043 VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKD 2102
V V+ D + I + +G+ G+CG +N ED+ M P +A + F NSW+
Sbjct: 297 VVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPG 356
Query: 2103 IDPSCQSLLVDEQ---QIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDL 2159
+ C + Q + + G+ RA A++ C L P + QC +++
Sbjct: 357 SESGCLDAVEVAQGCDPLGLIDADVEPGHLRA----EAQDVCHQLLEGP-FGQCHAQVSP 411
Query: 2160 TPF-----LVDCANTLCEFG--GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECP 2212
+ CA + G G QA+C ++ C + + WR FC CP
Sbjct: 412 AEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCP 470
Query: 2213 AYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDA 2272
Y++C+ C PSC + G+ E C GC C G + CVP + C C
Sbjct: 471 GGQLYSDCVSLCPPSC-EAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYYC 529
Query: 2273 HGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCS 2332
+P V C CVC G C CP+ +C+
Sbjct: 530 RQRYVP--GDTVRQLCNP-CVCRDGRWHCAQALCPA---------------------ECA 565
Query: 2333 VYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVI 2392
V GD YLTFDG SY G D + + LL G + L +
Sbjct: 566 VGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILLEHGACD-----AGSCLHAIS 620
Query: 2393 TTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFG-GRKN 2451
++ +QL+ ++VN Q + +P+ E L V L+ V +G
Sbjct: 621 VSLEDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPV 680
Query: 2452 AVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRA 2511
A I+L + V GLCG + +N+++D + P+G + ++ F + ++V +
Sbjct: 681 AYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKG-------R 733
Query: 2512 IPAEEEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQ 2570
P+E+ +S C+ Q + + AC +L F CH+ V EPF
Sbjct: 734 CPSEDSA-----------LLSPCTTHSQRHAFAEAACAIL--HSSVFQECHRLVDKEPFY 780
Query: 2571 EHCVLDLCSAQDPREQEELRCQVLSGH-------GVSSRYHISELYDTLPSILCQPGRPR 2623
C+ +C DP + C VLS + G S + TL ++C G+
Sbjct: 781 LRCLAAVCGC-DP--GSDCLCPVLSAYARRCAQEGASPPWR----NQTLCPVMCPGGQEY 833
Query: 2624 GLRGPLRGRLRQHPRLC---------------LQWHPE---PPLADCGCTSNGIYYQLGS 2665
P G+ P C L W PE P + C C Y GS
Sbjct: 834 RECAPACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGS 893
Query: 2666 SFLTEDCSQRCTCASSRILLCEPFSCRAGEVC--TLGNHTQGCF--PESPCLQNPCQNDG 2721
+ + E RC C + C C + C L C +SP + C
Sbjct: 894 ATMKE--CNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSC---- 947
Query: 2722 QCREQGATFTCECEVGYGGGLCMEPRDAPPPRKP 2755
G+T C C G + ++ R PP P
Sbjct: 948 ---PAGSTDGCVCP---PGTVLLDERCVPPDLCP 975
Score = 124 bits (310), Expect = 2e-27
Identities = 139/570 (24%), Positives = 204/570 (35%), Gaps = 117/570 (20%)
Query: 2191 CQSQGLKPPLWRN---SSFCPLE---CPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSAC 2244
CQ +GL R+ +FCP E P T PS + SC P+
Sbjct: 904 CQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSC------------PAGS 951
Query: 2245 AEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDF 2304
+GC+C PG VL +++CVP C C+ H G L + + C CVC G C
Sbjct: 952 TDGCVCPPGTVLLDERCVPPDLCPCR--HSGQWYLPNATIQEDCNV-CVCRGRQWHCTGQ 1008
Query: 2305 RCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVL 2364
R +S +C G P Y+TFDG ++ G Y+L++ L
Sbjct: 1009 R---------------------RSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGL 1047
Query: 2365 PEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVP-YRPNE 2423
V +N + + + G V + G + VN + P
Sbjct: 1048 ------FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGP 1101
Query: 2424 HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPS 2483
L + G L L T L + + G ++ L + G V+GLCG++D + ND+
Sbjct: 1102 GLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQ 1161
Query: 2484 GALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNS 2543
G L +SW + L P +P C+ +
Sbjct: 1162 GVLEPTAELAAHSWRL---SPLCPEPGDLP------------------HPCTMNTHRAGW 1200
Query: 2544 TQA-CRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHG---V 2599
+A C L P F CH V P+ E C+ D C + E L C ++ +
Sbjct: 1201 ARARCGALLQPL--FTLCHAEVPPQQHYEWCLYDACGCDSGGDCECL-CSAIATYADECA 1257
Query: 2600 SSRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGI 2659
+H+ L S+ C+ G+ GP P C + HPEP G
Sbjct: 1258 RHGHHVRWRSQELCSLQCEGGQVYEACGP------TCPPTCHEQHPEP----------GW 1301
Query: 2660 YYQLGSSFLTEDCSQRCTCASSRIL----LCEPFSCRAGEVCTLGNHTQGCFPESPCLQN 2715
+ Q+ + C + C C +L EP SC C G ++ FP LQ
Sbjct: 1302 HCQVVA------CVEGCFCPEGTLLHGGACLEPASC----PCEWGRNS---FPPGSVLQK 1348
Query: 2716 PCQNDGQCREQGATFTCECEVGYGGGLCME 2745
C G C Q + C G GG C E
Sbjct: 1349 DC---GNCTCQEGQWHC----GGDGGHCEE 1371
Score = 66.2 bits (160), Expect = 4e-10
Identities = 32/107 (29%), Positives = 44/107 (41%), Gaps = 4/107 (3%)
Query: 1808 CPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC 1867
C CP G C++ CP CS + C C + C C KG + CVP+G C
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
Query: 1868 GCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQIC 1914
CTD G G + ++ C C+C ++C C P C
Sbjct: 4118 DCTDAQGHSWAPGSQ--HQDACNN-CSCQA-GQLSCTAQPCPPPTHC 4160
Score = 63.5 bits (153), Expect = 3e-09
Identities = 37/96 (38%), Positives = 43/96 (44%), Gaps = 19/96 (19%)
Query: 1434 LCAK----PCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYF 1489
LC K PCP +C + CS CVE C C PG +L C+P S+C CL
Sbjct: 2626 LCQKGLVPPCPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCL------- 2678
Query: 1490 KVGERWYKPGCKEL------CVCESNNRIRCQPWRC 1519
VGE PG L CVCE + CQP C
Sbjct: 2679 -VGEELKWPGVSFLLGNCSQCVCE-KGELLCQPGGC 2712
Score = 61.6 bits (148), Expect = 1e-08
Identities = 41/138 (29%), Positives = 53/138 (38%), Gaps = 8/138 (5%)
Query: 2188 GATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR--CEGAKVPSACA 2245
GA C + + L N C CPA C C C DL C+ +V C
Sbjct: 4040 GAPCAGERHQARLC-NPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQV---CQ 4095
Query: 2246 EGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFR 2305
+GC C G + + CVP C C DA G S G C C G + C
Sbjct: 4096 KGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQ--HQDACNNCSCQAGQLSCTAQP 4153
Query: 2306 CPSGSHCQLTSDNSNSNC 2323
CP +HC + ++ S C
Sbjct: 4154 CPPPTHCAWSHWSAWSPC 4171
Score = 60.5 bits (145), Expect = 2e-08
Identities = 48/173 (27%), Positives = 66/173 (38%), Gaps = 35/173 (20%)
Query: 2189 ATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGC 2248
A CQ+Q + N CP ECP + C SC CW L + P C GC
Sbjct: 4797 APCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEP--CQPGC 4853
Query: 2249 ICQPGYVLSEDKCVPRSQCGCK------------DAHGGSIPLGKSWVSSGCTEKCVCTG 2296
C G +L CVP + C C + +P G + ++ CT +CVC G
Sbjct: 4854 GCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPG-TVLTRNCT-RCVCHG 4911
Query: 2297 GAIQCG--DFRCPSGSHCQ----------------LTSDNSNSNCVSDKSEQC 2331
GA C D + P G Q + + + SNC S ++ C
Sbjct: 4912 GAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGC 4964
Score = 59.7 bits (143), Expect = 4e-08
Identities = 30/80 (37%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 1055 CPASCKSPRP--SCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPN 1112
CP SC P+ SC C EGC C PG L D C+ S C C + PG + N
Sbjct: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
Query: 1113 CTEHCRCWPGSRVECQISQC 1132
C++ C C G + CQ C
Sbjct: 2695 CSQ-CVCEKGELL-CQPGGC 2712
Score = 58.5 bits (140), Expect = 9e-08
Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 9/89 (10%)
Query: 2221 LPSCSPSCWD--LDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIP 2278
+P C PSC D + C G C EGC C PG +L + +C+P S+C C P
Sbjct: 2632 VPPCPPSCLDPKANRSCSGH-----CVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWP 2686
Query: 2279 LGKSWVSSGCTEKCVCTGGAIQCGDFRCP 2307
G S++ C++ CVC G + C CP
Sbjct: 2687 -GVSFLLGNCSQ-CVCEKGELLCQPGGCP 2713
Score = 58.5 bits (140), Expect = 9e-08
Identities = 36/113 (31%), Positives = 43/113 (38%), Gaps = 15/113 (13%)
Query: 2203 NSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCE--------GAKVPSACAEGCICQPGY 2254
N+ C +CP N L + C G C G + CA GC C PG
Sbjct: 2878 NTQPCTAQCPE-----NMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGL 2932
Query: 2255 VLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCP 2307
L C+PRSQC C+ HG G C C C G + C RCP
Sbjct: 2933 FLHNASCLPRSQCPCQ-LHGQLYASGAMARLDSC-NNCTCVSGKMACTSERCP 2983
Score = 58.2 bits (139), Expect = 1e-07
Identities = 39/131 (29%), Positives = 52/131 (39%), Gaps = 12/131 (9%)
Query: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAK------PCPDTCHSGFSG 1449
C+ ++ TTC H+ C CP N + + PCP C + G
Sbjct: 2857 CSSLAPGDTTCPGP-HSQTRDCNTQPCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
Query: 1450 MFCSDRCVEACECNPGFVLSGLECIPRSQCGC-LHPAGSYFKVGERWYKPGCKELCVCES 1508
+ C+ C C C PG L C+PRSQC C LH G + G C C C S
Sbjct: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLH--GQLYASGAMARLDSCNN-CTCVS 2972
Query: 1509 NNRIRCQPWRC 1519
++ C RC
Sbjct: 2973 -GKMACTSERC 2982
Score = 57.4 bits (137), Expect = 2e-07
Identities = 59/202 (29%), Positives = 74/202 (36%), Gaps = 38/202 (18%)
Query: 1712 PESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPP--QSSFASCV 1769
PE+ E C L G C A W P GP+S C + +S +C
Sbjct: 3237 PEAEEEPCLLQG-----CDR---AGGWG--------PWGPWSHCSRSCGGGLRSRTRACD 3280
Query: 1770 HGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTC 1829
GD C +A +C QA P T C G+ YSPC PCP +C
Sbjct: 3281 QPPPQGLGD---YCEGPRAQGEVC-QALPCPV----TNCT--AIEGAEYSPCGPPCPRSC 3330
Query: 1830 SSINNPRDCPKALPCAESCECQKGHILS--GTSCVPLGQCGCTD-PAGSYHPVGERWYTE 1886
+ + C C C C G +LS G CV G C C D G H G R
Sbjct: 3331 DDLVH---C--VWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARP 3385
Query: 1887 NTCTRLCTCSVHNNITCFQSTC 1908
+ C CTC + + C C
Sbjct: 3386 DGCNH-CTC-LEGRLNCTDLPC 3405
Score = 57.0 bits (136), Expect = 3e-07
Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 3/120 (2%)
Query: 1751 PFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPM 1810
P +C V+ P S+++SC G + C A AQ + N CP
Sbjct: 4759 PHQEC-PVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCP- 4816
Query: 1811 RCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCT 1870
CPPG S C++ CP C + C + PC C C G +L +CVP C CT
Sbjct: 4817 ECPPGQVLSACATSCPCLCWHLQPGAICVQE-PCQPGCGCPGGQLLHNGTCVPPTACPCT 4875
Score = 53.9 bits (128), Expect = 2e-06
Identities = 42/134 (31%), Positives = 51/134 (38%), Gaps = 25/134 (18%)
Query: 2181 CQALQAFGATCQSQGLKPPLWRNSSFCPL-ECPAY--SSYTNCLPSCSPSCWDLDGRCEG 2237
C+ +A G CQ+ CP+ C A + Y+ C P C SC DL
Sbjct: 3291 CEGPRAQGEVCQALP-----------CPVTNCTAIEGAEYSPCGPPCPRSCDDL------ 3333
Query: 2238 AKVPSACAEGCICQPGYVLSEDK--CVPRSQCGCKDAHGGS--IPLGKSWVSSGCTEKCV 2293
C GC C PG VLS + CV C C D G P + GC C
Sbjct: 3334 VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNH-CT 3392
Query: 2294 CTGGAIQCGDFRCP 2307
C G + C D CP
Sbjct: 3393 CLEGRLNCTDLPCP 3406
Score = 53.1 bits (126), Expect = 4e-06
Identities = 35/117 (29%), Positives = 48/117 (41%), Gaps = 13/117 (11%)
Query: 1044 CPPNARYESCAC-PASC---KSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
CP + ++ CA PASC +PR + C GC C G L +N C+ C C +
Sbjct: 3090 CPRDKQWLDCAQGPASCAELSAPRGT-NQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEG 3148
Query: 1100 DYYEPGAEWFSP--NCT------EHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCH 1148
Y PG+ P NC+ +C WP + E S + C G CH
Sbjct: 3149 HLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPARCH 3205
Score = 53.1 bits (126), Expect = 4e-06
Identities = 36/114 (31%), Positives = 47/114 (41%), Gaps = 18/114 (15%)
Query: 2203 NSSFCPLECPAYSSY--TNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDK 2260
N CP EC A + +C C SC DL R + + P C GC C PG ++ + +
Sbjct: 4660 NGGPCP-ECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGP--CRPGCRCPPGQLVQDGR 4716
Query: 2261 CVPRSQCGCKDAHGGSIPLGKSW-------VSSGCTEKCVCTGGAIQCGDFRCP 2307
CVP S C C G SW V C + C C ++ C CP
Sbjct: 4717 CVPISSCRC-----GLPSANASWELAPAQAVQLDC-QNCTCVNESLVCPHQECP 4764
Score = 52.4 bits (124), Expect = 6e-06
Identities = 56/211 (26%), Positives = 81/211 (38%), Gaps = 36/211 (17%)
Query: 2192 QSQGLKPP--LWRNSSFCPLECPAYS-SYTNC---------------LPSCSPSCWDLDG 2233
Q+Q L P L RN + C A+S S +C L C +C +++
Sbjct: 4890 QAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNA 4949
Query: 2234 RCEGAKVPSACAEGCICQPGYVLSE-DKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKC 2292
+ SA A GC+CQPG+ S+ CVP C C +P G W + E C
Sbjct: 4950 TKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLP-GSEWQEA--CESC 5006
Query: 2293 VCTGG----AIQCGDFRCPSGSHCQLTSDNSNSNC----VSDKSEQCSVYGDPRYLTFDG 2344
+C G C C G L + +C ++S C + + R T G
Sbjct: 5007 LCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSPSCQLLTELRNFT-KG 5065
Query: 2345 FSYRLQGRMTY---VLIKTVDVLPEGVEPLL 2372
Y Q ++Y + V+PE EP L
Sbjct: 5066 TCYLDQVEVSYCSGYCPSSTHVMPE--EPYL 5094
Score = 52.0 bits (123), Expect = 8e-06
Identities = 31/102 (30%), Positives = 41/102 (40%), Gaps = 9/102 (8%)
Query: 1425 ACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIPRSQCGCL 1482
+C P ++ C PC C + S C D C C C G + CIP +C C
Sbjct: 4422 SCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCW 4481
Query: 1483 HP----AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCR 1520
H AG G+R + GCKE C C + C C+
Sbjct: 4482 HTSAAGAGMTLAPGDR-LQLGCKE-CECR-RGELHCTSQGCQ 4520
Score = 51.2 bits (121), Expect = 1e-05
Identities = 31/91 (34%), Positives = 38/91 (41%), Gaps = 8/91 (8%)
Query: 1048 ARYESCA--CPASCKSPRPSCGPLCREGCVCNPGFLFSDNH--CIQASSCNC--FYNNDY 1101
A Y C CP SC C C+ GC C PG + S N C+Q C+C
Sbjct: 3317 AEYSPCGPPCPRSCDD-LVHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQR 3375
Query: 1102 YEPGAEWFSPNCTEHCRCWPGSRVECQISQC 1132
+ PGA P+ HC C G R+ C C
Sbjct: 3376 HHPGARLARPDGCNHCTCLEG-RLNCTDLPC 3405
Score = 50.4 bits (119), Expect = 2e-05
Identities = 29/102 (28%), Positives = 40/102 (39%), Gaps = 12/102 (11%)
Query: 1041 TERCPPNARYESCA--------CPASCKSPRPS--CGPLCREGCVCNPGFLFSDNHCIQA 1090
T +CP N + S CP C + P C C GC C PG + C+
Sbjct: 2883 TAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPR 2942
Query: 1091 SSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQC 1132
S C C + Y GA +C +C C G ++ C +C
Sbjct: 2943 SQCPCQLHGQLYASGAMARLDSC-NNCTCVSG-KMACTSERC 2982
Score = 50.4 bits (119), Expect = 2e-05
Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 2/77 (2%)
Query: 1800 PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDC-PKALPCAESCECQKGHILSG 1858
P N T C C G S PC PCP +C ++ C P ++ C +C C G +
Sbjct: 3518 PCQENSTQCT-DCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQD 3576
Query: 1859 TSCVPLGQCGCTDPAGS 1875
CVP C C G+
Sbjct: 3577 GLCVPPAHCRCQYQPGA 3593
Score = 49.3 bits (116), Expect = 5e-05
Identities = 28/109 (25%), Positives = 41/109 (37%), Gaps = 5/109 (4%)
Query: 1419 PHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIPR 1476
P C CP + CA CP C G+ C D C + C C G + C+P
Sbjct: 4055 PMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPI 4114
Query: 1477 SQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFC 1525
C C G + G + ++ C C C++ ++ C C C
Sbjct: 4115 GHCDCTDAQGHSWAPGSQ-HQDACNN-CSCQA-GQLSCTAQPCPPPTHC 4160
Score = 48.1 bits (113), Expect = 1e-04
Identities = 38/122 (31%), Positives = 50/122 (40%), Gaps = 14/122 (11%)
Query: 1783 CRSLQAYASLCAQA-GQAPAWRNRTFCPMRCPPGSS------YSPCSSPCPDTCSSINNP 1835
C S Q CA G + R CP P ++ + PC+ PCP TC I+
Sbjct: 1776 CHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCA-PCPLTCDDISGQ 1834
Query: 1836 RDCPKALPC-AESCECQKGHILSGTS-CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLC 1893
CP PC + C C +G +L CV QC C Y P G+R + +LC
Sbjct: 1835 VTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWP-GQRIKAD---CQLC 1890
Query: 1894 TC 1895
C
Sbjct: 1891 IC 1892
Score = 48.1 bits (113), Expect = 1e-04
Identities = 33/94 (35%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 1430 SKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLS--GLECIPRSQCGCLH-PAG 1486
++YS C PCP +C + C RC C C PG VLS G C+ C CL G
Sbjct: 3317 AEYSPCGPPCPRSCDDL---VHCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTG 3373
Query: 1487 SYFKVGERWYKP-GCKELCVCESNNRIRCQPWRC 1519
G R +P GC C C R+ C C
Sbjct: 3374 QRHHPGARLARPDGCNH-CTC-LEGRLNCTDLPC 3405
Score = 47.8 bits (112), Expect = 2e-04
Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 2/66 (3%)
Query: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGC-- 1869
C P + C SPC C++ + + C PC C C KG + C+P +C C
Sbjct: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWH 4482
Query: 1870 TDPAGS 1875
T AG+
Sbjct: 4483 TSAAGA 4488
Score = 46.2 bits (108), Expect = 5e-04
Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Query: 1821 CSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDP-AGSYHPV 1879
C++ CP +C+ + + C + PC C C G ++ CVP+ C C P A + +
Sbjct: 4678 CANQCPHSCADLWDRVQCLQG-PCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWEL 4736
Query: 1880 GERWYTENTCTRLCTCSVHNNITCFQSTC 1908
+ C CTC V+ ++ C C
Sbjct: 4737 APAQAVQLDCQN-CTC-VNESLVCPHQEC 4763
Score = 45.8 bits (107), Expect = 6e-04
Identities = 29/101 (28%), Positives = 40/101 (39%), Gaps = 4/101 (3%)
Query: 1423 PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCL 1482
P CP + ++ CA+ P +C + + C C C G +L C+P C C
Sbjct: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
Query: 1483 HPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQE 1523
H G + G +P C E C C S C W C E
Sbjct: 3146 H-EGHLYPPGSTVVRP-C-ENCSCVSGLIANCSSWPCAEGE 3183
Score = 44.7 bits (104), Expect = 0.001
Identities = 49/209 (23%), Positives = 69/209 (33%), Gaps = 30/209 (14%)
Query: 1709 WKLPESSEPGCFLVGGKPSSCQENSMADA-WNKNCAILINPQGPFSQCHQVVP------- 1760
W S C GG P + + + + +C + P S VP
Sbjct: 2778 WTSWSSCSQSCLAPGGGPGWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWA 2837
Query: 1761 PQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSP 1820
P S+ ++ G T+G + C SL + C N C +CP +
Sbjct: 2838 PWSTCSAPCDGGIQTRGRS---CSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRS 2894
Query: 1821 CSS------PCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAG 1874
PCP C + +C CA C C G L SC+P QC C
Sbjct: 2895 AEQCHQEGGPCPRLCLTQGPGIECTGF--CAPGCTCPPGLFLHNASCLPRSQCPC----- 2947
Query: 1875 SYHPVGERWYTENTCTRLCTCSVHNNITC 1903
+ + Y RL +C NN TC
Sbjct: 2948 ---QLHGQLYASGAMARLDSC---NNCTC 2970
Score = 43.9 bits (102), Expect = 0.002
Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 8/103 (7%)
Query: 2208 PLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQC 2267
P CP + +C + SC +L C GC C G +L + CVP C
Sbjct: 3087 PGMCPRDKQWLDCAQGPA-SCAELSAP---RGTNQTCHPGCHCPSGMLLLNNVCVPTQDC 3142
Query: 2268 GCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAI-QCGDFRCPSG 2309
C AH G + S V C E C C G I C + C G
Sbjct: 3143 PC--AHEGHLYPPGSTVVRPC-ENCSCVSGLIANCSSWPCAEG 3182
Score = 43.9 bits (102), Expect = 0.002
Identities = 37/129 (28%), Positives = 49/129 (37%), Gaps = 23/129 (17%)
Query: 2199 PLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLD--GRCEGAKVPSACAEGCICQPGYVL 2256
P NS+ C +C S C C SC DL C+ V C C C G +
Sbjct: 3518 PCQENSTQCT-DCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSV--GCQPTCGCPLGQLS 3574
Query: 2257 SEDKCVPRSQCGCKDAHGG-SIPLGK---------SW-------VSSGCTEKCVCTGGAI 2299
+ CVP + C C+ G IP + SW V +G + C C G +
Sbjct: 3575 QDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGIL 3634
Query: 2300 QCGDF-RCP 2307
QC + CP
Sbjct: 3635 QCQEVPDCP 3643
Score = 43.9 bits (102), Expect = 0.002
Identities = 22/61 (36%), Positives = 26/61 (42%), Gaps = 2/61 (3%)
Query: 1422 CPMACPPNSKYSLCAKPCPDTCHSGFSGMFC-SDRCVEACECNPGFVLSGLECIPRSQCG 1480
CP CPP S CA CP C G C + C C C G +L C+P + C
Sbjct: 4815 CP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACP 4873
Query: 1481 C 1481
C
Sbjct: 4874 C 4874
Score = 43.5 bits (101), Expect = 0.003
Identities = 35/146 (23%), Positives = 52/146 (35%), Gaps = 20/146 (13%)
Query: 1774 GTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSIN 1833
G + T RSL +++ Q P P CP + C+ P +C+ ++
Sbjct: 3059 GYRNRTRGSSRSLMEFSTCGLQPCAGPV-------PGMCPRDKQWLDCAQG-PASCAELS 3110
Query: 1834 NPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLC 1893
PR + C C C G +L CVP C C Y P +T R C
Sbjct: 3111 APRGTNQT--CHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPP-------GSTVVRPC 3161
Query: 1894 -TCSVHNNI--TCFQSTCKPNQICWA 1916
CS + + C C + W+
Sbjct: 3162 ENCSCVSGLIANCSSWPCAEGEPTWS 3187
Score = 42.7 bits (99), Expect = 0.005
Identities = 18/46 (39%), Positives = 22/46 (47%), Gaps = 2/46 (4%)
Query: 1824 PCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGC 1869
PCP +C R C C E C C G +L T C+PL +C C
Sbjct: 2634 PCPPSCLDPKANRSCSGH--CVEGCRCPPGLLLHDTRCLPLSECPC 2677
Score = 42.7 bits (99), Expect = 0.005
Identities = 22/45 (48%), Positives = 23/45 (51%), Gaps = 5/45 (11%)
Query: 1055 CPASCKS--PRPSC--GPLCREGCVCNPGFLFSDNHCIQASSCNC 1095
CP SC R C GP CR GC C PG L D C+ SSC C
Sbjct: 4682 CPHSCADLWDRVQCLQGP-CRPGCRCPPGQLVQDGRCVPISSCRC 4725
Score = 42.0 bits (97), Expect = 0.009
Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 10/102 (9%)
Query: 1044 CPPNARYESCA--CPASCKSPRPSC----GPLCREGCVCNPGFLFSDNHCIQASSCNCFY 1097
CP +CA CP C + +C++GC C G L D C+ C+C
Sbjct: 4062 CPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHCDCTD 4121
Query: 1098 NNDY-YEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVC 1138
+ + PG++ + +C C G ++ C C T C
Sbjct: 4122 AQGHSWAPGSQ--HQDACNNCSCQAG-QLSCTAQPCPPPTHC 4160
Score = 42.0 bits (97), Expect = 0.009
Identities = 28/114 (24%), Positives = 41/114 (35%), Gaps = 26/114 (22%)
Query: 1045 PPNARYESCA------CPASC-----KSPRPSCGPLCREGCVCNPGFLFSD-NHCIQASS 1092
PP ++ A C +C + +C GCVC PG S C+
Sbjct: 4924 PPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH 4983
Query: 1093 CNCFYNNDYYEPGAEWFS-----------PNCTEHC---RCWPGSRVECQISQC 1132
C C++ + PG+EW P CT+HC C G + + C
Sbjct: 4984 CECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSC 5037
Score = 40.8 bits (94), Expect = 0.019
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 6/84 (7%)
Query: 1410 GHAVKPWREPHF----CPMACPPNSKYSL-CAKPCPDTCHSGFSGMFC-SDRCVEACECN 1463
G +PW + CP ++ ++L CA CP +C + + C C C C
Sbjct: 4648 GGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCP 4707
Query: 1464 PGFVLSGLECIPRSQCGCLHPAGS 1487
PG ++ C+P S C C P+ +
Sbjct: 4708 PGQLVQDGRCVPISSCRCGLPSAN 4731
Score = 38.5 bits (88), Expect = 0.095
Identities = 31/107 (28%), Positives = 45/107 (42%), Gaps = 22/107 (20%)
Query: 1044 CPPNARYESCA--CPASCKSPRPSCGPL---CREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
CPP +CA CP C +P + C+ GC C G L + C+ ++C C +
Sbjct: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQH 4877
Query: 1099 NDYY------EPGAEWFSP------NCTEHCRCWPG----SRVECQI 1129
+ + E A+ P NCT C C G S V+CQ+
Sbjct: 4878 SLPWGLTLTLEEQAQELPPGTVLTRNCT-RCVCHGGAFSCSLVDCQV 4923
Score = 37.7 bits (86), Expect = 0.16
Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 6/69 (8%)
Query: 1037 SRSSTERCPPNARYESCACPAS--CKS--PRPSCG--PLCREGCVCNPGFLFSDNHCIQA 1090
S S + C P + +C P + C + C P C+ GC C G L CI
Sbjct: 4416 SNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPP 4475
Query: 1091 SSCNCFYNN 1099
CNC++ +
Sbjct: 4476 EECNCWHTS 4484
Score = 37.4 bits (85), Expect = 0.21
Identities = 48/164 (29%), Positives = 63/164 (38%), Gaps = 22/164 (13%)
Query: 1786 LQAYASLC-AQAGQAPAWRNRTFCPMRCPPGSSYSP---CSSPCPD-----TCSSINNPR 1836
++A LC Q G+ R C + C SS+SP C PC + S NNPR
Sbjct: 1883 IKADCQLCICQDGRPRRCRLNPDCAVDCG-WSSWSPWAKCLGPCGSQSIQWSFRSSNNPR 1941
Query: 1837 DCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCS 1896
+ C +G C GC + G H VGERW+ C R+C C
Sbjct: 1942 PSGRGRQC-------RGIHRKARRCQTEPCEGC-EHQGQVHRVGERWH-GGPC-RVCQCL 1991
Query: 1897 VHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYV 1940
+N+T S P C L+ C LPGE+ V
Sbjct: 1992 --HNLTAHCSPYCPLGSCPQGWVLVEGTGESCCHCALPGENQTV 2033
Score = 37.4 bits (85), Expect = 0.21
Identities = 27/109 (24%), Positives = 38/109 (34%), Gaps = 5/109 (4%)
Query: 1384 DMCGFQGLQHLLCTHMSTMT--TTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPD 1441
DMC Q + C+ T C +P +E C C +PCP
Sbjct: 3485 DMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPR 3544
Query: 1442 TCHSGFSGMFC---SDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGS 1487
+C G C S C C C G + C+P + C C + G+
Sbjct: 3545 SCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGA 3593
Score = 36.6 bits (83), Expect = 0.36
Identities = 20/66 (30%), Positives = 26/66 (39%), Gaps = 4/66 (6%)
Query: 2244 CAEGCICQPGYVLSEDKCVPRSQCGC--KDAHGGSIPLGK-SWVSSGCTEKCVCTGGAIQ 2300
C GC C G + C+P +C C A G + L + GC E C C G +
Sbjct: 4455 CQPGCYCPKGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKE-CECRRGELH 4513
Query: 2301 CGDFRC 2306
C C
Sbjct: 4514 CTSQGC 4519
Score = 36.2 bits (82), Expect = 0.47
Identities = 24/76 (31%), Positives = 28/76 (36%), Gaps = 7/76 (9%)
Query: 1452 CSDRCVEACECNPGFVLSGL-ECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNN 1510
CS C C PG S C+P C C H G G W + C E C+C S
Sbjct: 4956 CSSARASGCVCQPGHFRSQAGPCVPEDHCECWH-LGRPHLPGSEW-QEAC-ESCLCLSGR 5012
Query: 1511 RI---RCQPWRCRAQE 1523
+ C P C E
Sbjct: 5013 PVCTQHCSPLTCAQGE 5028
Score = 35.4 bits (80), Expect = 0.80
Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 10/57 (17%)
Query: 1055 CPASCK--SPRPSCGPL---CREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGA 1106
CP SC+ SP C P C+ C C G L D C+ + C C Y+PGA
Sbjct: 3542 CPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRC-----QYQPGA 3593
Score = 35.4 bits (80), Expect = 0.80
Identities = 29/115 (25%), Positives = 39/115 (33%), Gaps = 22/115 (19%)
Query: 1812 CPPGSSYSPCS--SPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGC 1869
CP G Y C CP +C+ + C C E C C +G +CV +C C
Sbjct: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSE-GCEEGCHCPEGTFQHRLACVQ--ECPC 3753
Query: 1870 T--------------DPAGSYHPVGE--RWYTENTCTRLCTCSVHNNITCFQSTC 1908
DP P E T T C+C+ H ++C C
Sbjct: 3754 VLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCA-HGKLSCSLDDC 3807
Score = 35.0 bits (79), Expect = 1.0
Identities = 35/142 (24%), Positives = 49/142 (34%), Gaps = 27/142 (19%)
Query: 1363 GPFETCLLHVKAASFFDS--CMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPH 1420
GP+E C + S C C Q C+ T C++AG
Sbjct: 3652 GPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCS-----TQVCREAG---------- 3696
Query: 1421 FCPMACPPNSKYSLC--AKPCPDTCHSGFSGMFC-SDRCVEACECNPGFVLSGLECIPRS 1477
CP Y C + CP +C + C S+ C E C C G L C+
Sbjct: 3697 -----CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACV--Q 3749
Query: 1478 QCGCLHPAGSYFKVGERWYKPG 1499
+C C+ A ++G PG
Sbjct: 3750 ECPCVLTAWLLQELGATIGDPG 3771
Score = 34.7 bits (78), Expect = 1.4
Identities = 36/140 (25%), Positives = 52/140 (37%), Gaps = 26/140 (18%)
Query: 2174 GGLYQALCQ--ALQAFGATCQSQGLKPPL---WRNSSFCPLECPAYSSYTNCLPSCSPSC 2228
G +Q C + QA +C +Q PP W + +S+++ C SC P
Sbjct: 4130 GSQHQDACNNCSCQAGQLSCTAQPCPPPTHCAWSH----------WSAWSPCSHSCGPRG 4179
Query: 2229 WDLDGRCE--GAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSS 2286
R G+ P E QP + C P G + S LG SW+
Sbjct: 4180 QQSRFRSSTSGSWAPECREEQSQSQP---CPQPSCPPLCLQGTR-----SRTLGDSWLQG 4231
Query: 2287 GCTEKCVCTGGAIQCGDFRC 2306
C ++C CT + C D C
Sbjct: 4232 EC-QRCSCTPEGVICEDTEC 4250
Score = 33.9 bits (76), Expect = 2.3
Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 2/48 (4%)
Query: 2648 PLADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGE 2695
P DC C G Y GS+ + C + C+C S I C + C GE
Sbjct: 3138 PTQDCPCAHEGHLYPPGST-VVRPC-ENCSCVSGLIANCSSWPCAEGE 3183
Score = 33.5 bits (75), Expect = 3.0
Identities = 32/115 (27%), Positives = 44/115 (38%), Gaps = 36/115 (31%)
Query: 1037 SRSSTERCP----PNAR------YESCA-CPASCK--SPRPSCGP---LCREGCVCNPG- 1079
S T+ CP PNA ++ CA CP +C S + +C P GC C G
Sbjct: 1795 STRQTKPCPQDGCPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQ 1854
Query: 1080 FLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRV--ECQISQC 1132
L S+ C+ C C + Y WPG R+ +CQ+ C
Sbjct: 1855 VLGSEGWCVWPRQCPCLVDGARY-----------------WPGQRIKADCQLCIC 1892
Score = 32.0 bits (71), Expect = 8.8
Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 2/38 (5%)
Query: 1480 GCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPW 1517
GC H G +VGERW+ C+ +C C N C P+
Sbjct: 1966 GCEHQ-GQVHRVGERWHGGPCR-VCQCLHNLTAHCSPY 2001
Score = 32.0 bits (71), Expect = 8.8
Identities = 20/68 (29%), Positives = 22/68 (32%), Gaps = 7/68 (10%)
Query: 1033 TTTTSRSSTERCPPNARYESC----ACPASCKSPRPSCGPL---CREGCVCNPGFLFSDN 1085
T +T CP Y C CP SC G C EGC C G
Sbjct: 3686 TCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRL 3745
Query: 1086 HCIQASSC 1093
C+Q C
Sbjct: 3746 ACVQECPC 3753
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 258 bits (658), Expect = 8e-68
Identities = 305/1317 (23%), Positives = 479/1317 (36%), Gaps = 269/1317 (20%)
Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
A C+ GD HY TFDG + F G C YV + C + +D F V RG +
Sbjct: 727 AHNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYED--FNVQL---RRGLVGS 781
Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQ 1655
+ V + L + G V++NG R LP ++ + + S + + + L
Sbjct: 782 RPVVTRVVIKAQGLVLEASNG-SVLINGQREELPY--SRTGLLVEQSGDYIKVSIRLVLT 838
Query: 1656 VRYDGSHLVEVTVPSSYGGQLCGLCGNYNN-NSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714
++G + + Y Q CGLCG++N + ++ + +L +Q G KL
Sbjct: 839 FLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLT--PLQFGNLQKLDGP 896
Query: 1715 SEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG 1774
+E C P + D L+ P F++CH +V + A+C C
Sbjct: 897 TEQ-C----PDPLPLPAGNCTDEEGICHRTLLGPA--FAECHALVDSTAYLAACAQDLCR 949
Query: 1775 TKGDTTALCRSLQAYASLCAQAGQAPA-WRNRTFCPMRCPPGSSYSPCSSPCPDTCSSIN 1833
T C + Y+ CA AG P WR CP CP + C SPC DTCS+
Sbjct: 950 CP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQ 1006
Query: 1834 NPRDCPKALPCAESCECQKGHI------LSGTSCVPLGQCGCTDPAGSYHPVGERWYTEN 1887
+ C C + C C G ++ + C+PLGQC CT +Y P + N
Sbjct: 1007 RAQLCEDH--CVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSP----GTSFN 1060
Query: 1888 TCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGV-GVCQLPGESHYVSFDGSN 1946
T CTCS GL +C+ G C + G +H ++D
Sbjct: 1061 TTCSSCTCS---------------------GGLWQCQDLPCPGTCSVQGGAHISTYDEKL 1099
Query: 1947 HSIPDACTLVLVKVCHPAMALPFFKISAKHEK-----EEGGTEAFRLHEVYIDIYDAQVT 2001
+ + C+ VL K C + F + A+ K E +A L +D D +
Sbjct: 1100 YDLHGDCSYVLSKKCADSS----FTVLAELRKCGLTDNENCLKAVTLS---LDGGDTAIR 1152
Query: 2002 LQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEI--EIPT 2059
+Q V +NS LP +S SS + +V +G+Q+ L+++ +
Sbjct: 1153 VQADGGVFLNSIYTQLP-LSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDP 1211
Query: 2060 TYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPA 2119
+ G++CG+CGNFN + D+ S V + + F N+WK + + ++ D +
Sbjct: 1212 AHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLSV 1271
Query: 2120 EQQENPSGNC-RAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQ 2178
E + C R D A +++C S I+ PF +C C
Sbjct: 1272 ENENYARHWCSRLTDPNSA------------FSRCHSIINPKPFHSNCMFDTCNCERSED 1319
Query: 2179 ALCQALQAFGATCQSQGLKPPLWRNSSFCPL--ECPAYSSYTNCLPSCSPSCWDL---DG 2233
LC AL ++ C ++G++ WR+ CP Y + +C P+C L D
Sbjct: 1320 CLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADV 1379
Query: 2234 RCEGAKVP---------------SAC---------AEGCICQPGYVLSEDKCV------- 2262
C + VP AC A G + PG V+ ++ V
Sbjct: 1380 TCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGK 1439
Query: 2263 ----------------PRSQCGCKDAHGGSI---------PLGKSWVSSGCTEKCVCTGG 2297
P C ++ G+ L S+ C CVC G
Sbjct: 1440 LSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPG 1499
Query: 2298 AIQCGDFRCPSGSHCQ-------------LTSDNSNSNCVSDKSE--------QCSVYGD 2336
+ G C + C + D + C + + E C YGD
Sbjct: 1500 LVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGD 1559
Query: 2337 PRYLTFDGFSYRLQGRMTYVLIK----------TVDVLPEGVE------------PLLVE 2374
++TFDG Y +G Y+L + T ++ E + L VE
Sbjct: 1560 GHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVE 1619
Query: 2375 GR------------NKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPN 2422
R N+ P +S+ ++ + + Y++ LQ G V P
Sbjct: 1620 VRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKAVARGPGGDPPYKI 1679
Query: 2423 EHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLP 2482
++ + L ++ + VS+ + + I L Y+G V GLCGN+D N ND
Sbjct: 1680 RYMGIFL------VIETHGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATR 1733
Query: 2483 SGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASN 2542
S ++ + FGNSW++ P A+ ++ C+ +
Sbjct: 1734 SRSVVGDALEFGNSWKLSPS-----CPDALAPKD----------------PCTANPFRKS 1772
Query: 2543 STQ-ACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSS 2601
Q C +L P FAAC V + E CV D C+ + E C + +
Sbjct: 1773 WAQKQCSILHGP--TFAACRSQVDSTKYYEACVNDACACDSGGDCE---CFCTAVAAYAQ 1827
Query: 2602 RYHISELY------DTLPSILCQPGRPRG----------------LRGPLRGRLRQHPRL 2639
H + L DT P + C P G R P L P L
Sbjct: 1828 ACHDAGLCVSWRTPDTCP-LFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGL 1886
Query: 2640 CLQWHPEPP------------LADCGC-TSNGIYYQLGSSFLTEDCSQRCTCASSRI 2683
+ PP +A CGC +G YY +G+ T + Q C C S I
Sbjct: 1887 EGCYPKCPPSQPFFNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENCQSCNCTPSGI 1943
Score = 254 bits (648), Expect = 1e-66
Identities = 211/807 (26%), Positives = 327/807 (40%), Gaps = 88/807 (10%)
Query: 1148 HPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEG 1207
+P C +GD HY TFDG F F G C Y+ ++ C + + F V + G
Sbjct: 725 NPAHNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDF-NVQLRRGLVGSRP 783
Query: 1208 VSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRV 1267
V +++V + + G L+ GQ+ LP G+ + SG ++++ L
Sbjct: 784 V--VTRVVIKAQGLVLEASNGS-VLINGQREELP-YSRTGLLVEQSGDYIKVSIRLVLTF 839
Query: 1268 RWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDED 1327
W+G+ + + Y+ + CGLCG+++G + + + GN + D +
Sbjct: 840 LWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ-FGNLQKLDGPTE 898
Query: 1328 QECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLDMC 1386
Q C + + +C G C R + GP F C V + ++ +C D+C
Sbjct: 899 Q-CPDPLPLPAGNCTDE-------EGICHRTL--LGPAFAECHALVDSTAYLAACAQDLC 948
Query: 1387 GFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSG 1446
C + C AG + WR P CP CP N ++ C PC DTC +
Sbjct: 949 RCPTCP---CATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNP 1005
Query: 1447 FSGMFCSDRCVEACECNPGFVLSGLE------CIPRSQCGCLHPAGSYFKVGERWYKPGC 1500
C D CV+ C C PG + L+ C+P QC C H G R Y PG
Sbjct: 1006 QRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTH--------GGRTYSPGT 1057
Query: 1501 KELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH-AQGAATCTASGDPHYLTFDGALHH 1559
C S C G++ C TC+ G H T+D L+
Sbjct: 1058 SFNTTCSS----------------CTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYD 1101
Query: 1560 FMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTV--FDLSISLLRGC 1617
G C+YVL++ C DS F V A G + +KAV +++ D +I +
Sbjct: 1102 LHGDCSYVLSKKC----ADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADG 1157
Query: 1618 KVMLNGHRVALPVWLAQGRVTI-RLSSNLVLLYTNFGLQVRYDGSHLVEVTV--PSSYGG 1674
V LN LP L+ +T+ SS +++ T GLQ+ L++V V ++ G
Sbjct: 1158 GVFLNSIYTQLP--LSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQG 1215
Query: 1675 QLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLP-------ESSEPGCFLVGGKPS 1727
Q+CGLCGN+N N DD + WK S E C L
Sbjct: 1216 QMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSL------ 1269
Query: 1728 SCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQ 1787
S + + A W C+ L +P FS+CH ++ P+ ++C+ C + LC +L
Sbjct: 1270 SVENENYARHW---CSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALS 1326
Query: 1788 AYASLCAQAG-QAPAWRNR--TFCPMRCPPGSSYSPCSSPCPDTCSSINNPR-DCPKALP 1843
+Y CA G Q WR+ T CP Y+ C TC ++ C +
Sbjct: 1327 SYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFV 1386
Query: 1844 CAESCECQKGHILSGT-SCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNIT 1902
+ C C G L+ +CVP +C C G+ GE + E +C+C+ ++
Sbjct: 1387 PVDGCTCPAGTFLNDAGACVPAQECPCY-AHGTVLAPGEVVHDEGA---VCSCT-GGKLS 1441
Query: 1903 CFQSTCKPNQICWALDGLLRCRASGVG 1929
C ++ + + C A L C S G
Sbjct: 1442 CLGASLQKSTGCAAPMVYLDCSNSSAG 1468
Score = 221 bits (562), Expect = 1e-56
Identities = 165/554 (29%), Positives = 246/554 (44%), Gaps = 56/554 (10%)
Query: 1148 HPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEG 1207
+P C +G HY TFDG F F G C Y+ ++ CG + + F +++E
Sbjct: 73 NPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESA--- 129
Query: 1208 VSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRV 1267
LS+V + + + L KG LV G V LP S GV + S + +++ GL +
Sbjct: 130 APTLSRVLMKVDGVVIQLTKGS-VLVNGHPVLLPFSQS-GVLIQQSSSYTKVEARLGLVL 187
Query: 1268 RWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDED 1327
W+ D L + + + Y+ K CGLCG+++G L L + E GN + D D
Sbjct: 188 MWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSEL-LSHNTKLTPMEFGNLQKMD-DPT 245
Query: 1328 QECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLDMC 1386
++CQ V P + S +G G C L+ HG F C+ V S+ ++C D+C
Sbjct: 246 EQCQ--DPVPEPPRNCS-----TGFGICEELL--HGQLFSGCVALVDVGSYLEACRQDLC 296
Query: 1387 GFQGLQHL--LCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH 1444
+ L +C ++ + C AG + WR P FCP CP N +Y C PC DTC
Sbjct: 297 FCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCS 356
Query: 1445 SGFSGMFCSDRCVEACECNPGFVLSGL---ECIPRSQCGCLHPAGSYFKVGERWYKPGCK 1501
+ C D CV C C G VL + C+P S+C C++ +Y Y C
Sbjct: 357 NQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAY--APGATYSTDCT 414
Query: 1502 ELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFM 1561
C C S R CQ C TC+ G H+ TFDG +
Sbjct: 415 N-CTC-SGGRWSCQEVPC-------------------PGTCSVLGGAHFSTFDGKQYTVH 453
Query: 1562 GTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTV--FDLSISLLRGCKV 1619
G C+YVLT+PC S F V A G + +K+V +++ + + +V
Sbjct: 454 GDCSYVLTKPC----DSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEV 509
Query: 1620 MLNGHRVALPVWLAQGRVTI-RLSSNLVLLYTNFGLQVRYDGSHLVE--VTVPSSYGGQL 1676
LN LP+ + VTI R S+ ++ T+ GLQ+ ++ + + GQ
Sbjct: 510 FLNQIYTQLPI--SAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQT 567
Query: 1677 CGLCGNYNNNSLDD 1690
CGLCGN+N+ DD
Sbjct: 568 CGLCGNFNSIQADD 581
Score = 193 bits (490), Expect = 2e-48
Identities = 162/597 (27%), Positives = 254/597 (42%), Gaps = 61/597 (10%)
Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
A C+ G HY TFDG + F G C YV + C + +D + + E+ L
Sbjct: 75 AHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLS 134
Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQ 1655
+K V I L +G V++NGH V LP +Q V I+ SS+ + GL
Sbjct: 135 RVLMKVDGVV-----IQLTKG-SVLVNGHPVLLP--FSQSGVLIQQSSSYTKVEARLGLV 186
Query: 1656 VRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSL-DDNLRPDRKLAGDSMQLGAAWKLPES 1714
+ ++ + + + + Y + CGLCG++N + + L + KL M+ G K+ +
Sbjct: 187 LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMDDP 244
Query: 1715 SEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG 1774
+E V P +C C L++ Q FS C +V S +C C
Sbjct: 245 TEQCQDPVPEPPRNCSTGFGI------CEELLHGQ-LFSGCVALVDVGSYLEACRQDLCF 297
Query: 1775 TKGDTTAL---CRSLQAYASLCAQAGQAPA-WRNRTFCPMRCPPGSSYSPCSSPCPDTCS 1830
+ DT L C +L Y+ C AG P WR FCP +CP Y C SPC DTCS
Sbjct: 298 CE-DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCS 356
Query: 1831 SINNPRDCPKALPCAESCECQKGHILSG---TSCVPLGQCGCTDPAGSYHPVGERWYTEN 1887
+ + R C C C C +G +L T CVP+ +C C +Y P G + T+
Sbjct: 357 NQEHSRACED--HCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP-GATYSTD- 412
Query: 1888 TCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNH 1947
CT CTCS +C + C G C + G +H+ +FDG +
Sbjct: 413 -CTN-CTCS-GGRWSCQEVPCP-------------------GTCSVLGGAHFSTFDGKQY 450
Query: 1948 SIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQ--VTLQKG 2005
++ C+ VL K C + F + A+ + L V + + AQ V ++
Sbjct: 451 TVHGDCSYVLTKPCDSSA----FTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKAS 506
Query: 2006 HRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFD--GNHLLEIEIPTTYYG 2063
V +N LP IS + S+ + I +G+Q+ L +++ G
Sbjct: 507 GEVFLNQIYTQLP-ISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRG 565
Query: 2064 KVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAE 2120
+ CG+CGNFN + D+ S V + + F N++K + P+ ++ D + E
Sbjct: 566 QTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVE 622
Score = 186 bits (473), Expect = 2e-46
Identities = 164/566 (28%), Positives = 226/566 (39%), Gaps = 118/566 (20%)
Query: 1055 CPASCKSPRPSC-GPLCREGCVCNPGFLFSDNH--CIQASSCNCFYNNDYYEPGAEWFSP 1111
C SC + C C GCVC PG L SD CI C C +N Y+PG
Sbjct: 1474 CLRSCHTLDVGCFSTHCVSGCVCPPG-LVSDGSGGCIAEEDCPCVHNEATYKPGET---- 1528
Query: 1112 NCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRH 1171
RV+C C +N ++ C TC+ YGD H++TFDG
Sbjct: 1529 -----------IRVDCN--------TCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDR 1569
Query: 1172 FGFMGKCTYILAQP-CG-NSTDPFFRVTAKNEEQGQEGVSCLSKVY----------VTLP 1219
+ F G C YILAQ CG N+T FR+ +N G G +C + V+ P
Sbjct: 1570 YSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTP 1629
Query: 1220 ESTVTLLKGRRTLVGGQQVTLPAIPS------KGVFLGAS--------------GRFVEL 1259
+ R VG +Q LP + S +G F + G F+ +
Sbjct: 1630 DPAANEPAPREASVGFRQ-RLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVI 1688
Query: 1260 QTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNS 1319
+T G+ V WD +++ + Y G++CGLCGN+D N+ ND S GD E GNS
Sbjct: 1689 ETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNS 1747
Query: 1320 WQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP-FETCLLHVKAASFF 1378
W+ C P + + S + C L HGP F C V + ++
Sbjct: 1748 WKL----SPSCPDALAPKDPCTANPFRKSWAQKQ-CSIL---HGPTFAACRSQVDSTKYY 1799
Query: 1379 DSCMLDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACP---PNS--- 1430
++C+ D C G CT ++ C DAG V WR P CP+ C P+
Sbjct: 1800 EACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVS-WRTPDTCPLFCDFYNPHGGCE 1858
Query: 1431 -KYSLCAKPCPDTCHSGFSGMFCSDRCVEAC--ECNPG---FVLSGLECIPRSQCGCLHP 1484
Y C PC TC + +E C +C P F ++C+ +QCGC
Sbjct: 1859 WHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCV--AQCGCYDK 1916
Query: 1485 AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCT- 1543
G+Y+ VG R P + C+S N C P GI H+ A TCT
Sbjct: 1917 DGNYYDVGAR--VPTAEN---CQSCN---CTP------------SGIQCAHSLEACTCTY 1956
Query: 1544 -----ASGDPHYLTFDGALHHFMGTC 1564
+ D Y T DG +G C
Sbjct: 1957 EDRTYSYQDVIYNTTDG-----LGAC 1977
Score = 180 bits (457), Expect = 2e-44
Identities = 159/571 (27%), Positives = 226/571 (39%), Gaps = 96/571 (16%)
Query: 1429 NSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLE-CIPRSQCGCLHPAGS 1487
NS C +CH+ G F S CV C C PG V G CI C C+H
Sbjct: 1464 NSSAGTPGAECLRSCHTLDVGCF-STHCVSGCVCPPGLVSDGSGGCIAEEDCPCVH---- 1518
Query: 1488 YFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEF-CGQQDGIYGCHAQGAATCTASG 1546
E YKPG R+ C CR + + C H TC A G
Sbjct: 1519 ----NEATYKPG--------ETIRVDCNTCTCRNRRWECS--------HRLCLGTCVAYG 1558
Query: 1547 DPHYLTFDGALHHFMGTCTYVLTRP-CWSRSQDSYFVVSATNENRGG-----------IL 1594
D H++TFDG + F G+C Y+L + C + F + N G +
Sbjct: 1559 DGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFV 1618
Query: 1595 EVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALP------VWLAQGRVT---------- 1638
EV AV + R V G R LP + L +G
Sbjct: 1619 EVRTAPAVSTPDPAANEPAPREASV---GFRQRLPPLQSYELILQEGTFKAVARGPGGDP 1675
Query: 1639 ---IRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPD 1695
IR +++ T+ G+ V +D V + + Y G++CGLCGN+++N+++D
Sbjct: 1676 PYKIRYMGIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRS 1734
Query: 1696 RKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQ 1754
R + GD+++ G +WKL P C C N +W K C+IL P F+
Sbjct: 1735 RSVVGDALEFGNSWKL----SPSCPDALAPKDPCTANPFRKSWAQKQCSILHGP--TFAA 1788
Query: 1755 CHQVVPPQSSFASCVHGQCG--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812
C V + +CV+ C + GD C ++ AYA C AG +WR CP+ C
Sbjct: 1789 CRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFC 1848
Query: 1813 ----PPGS---SYSPCSSPCPDTCSSINNPRDCPKALPCAESC--ECQKGH-ILSGTSCV 1862
P G Y PC +PC TC N C LP E C +C +
Sbjct: 1849 DFYNPHGGCEWHYQPCGAPCLKTCR--NPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMK 1906
Query: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQS----TCKPNQICWALD 1918
+ QCGC D G+Y+ VG R T C + C C+ + I C S TC ++
Sbjct: 1907 CVAQCGCYDKDGNYYDVGARVPTAENC-QSCNCT-PSGIQCAHSLEACTCTYEDRTYSYQ 1964
Query: 1919 GLLRCRASGVGVCQLPGESHYVSFDGSNHSI 1949
++ G+G C ++ GSN +I
Sbjct: 1965 DVIYNTTDGLGAC-------LIAICGSNGTI 1988
Score = 171 bits (432), Expect = 1e-41
Identities = 155/586 (26%), Positives = 234/586 (39%), Gaps = 77/586 (13%)
Query: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
VC G HY +FDG P C V + C A F I + +E A L
Sbjct: 80 VCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHC--GAAYEDFNIQLRRSQESA---APTLS 134
Query: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049
V + + + L KG VL+N V LP SQ GV ++ SS Y+ V ++G+ + ++
Sbjct: 135 RVLMKVDGVVIQLTKGS-VLVNGHPVLLP-FSQ-SGVLIQQSSSYTKVEARLGLVLMWNH 191
Query: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQS 2109
+ L +E+ T Y K CG+CG+FN ++ S + EF N K D CQ
Sbjct: 192 DDSLLLELDTKYANKTCGLCGDFNGMPVVSELL-SHNTKLTPMEFGNLQKMDDPTEQCQD 250
Query: 2110 LLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANT 2169
+ + P NC CE L +++ C + +D+ +L C
Sbjct: 251 PVPE-----------PPRNCSTGF-----GICEELLHGQLFSGCVALVDVGSYLEACRQD 294
Query: 2170 LC--EFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPS 2227
LC E L +C L + C G P WR FCP +CP Y C C+ +
Sbjct: 295 LCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADT 354
Query: 2228 CWDLDGRCEGAKVPSACAEGCICQPGYVL---SEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284
C + + C GC C G VL + CVP S+C C + G+ +
Sbjct: 355 CSNQE---HSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCAC--VYNGAAYAPGATY 409
Query: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344
S+ CT C C+GG C + CP CSV G + TFDG
Sbjct: 410 STDCT-NCTCSGGRWSCQEVPCPG---------------------TCSVLGGAHFSTFDG 447
Query: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYK--VQL 2402
Y + G +YVL K D +L E R + S L+ V ++ G + V +
Sbjct: 448 KQYTVHGDCSYVLTKPCD---SSAFTVLAELR-RCGLTDSETCLKSVTLSLDGAQTVVVI 503
Query: 2403 QAGLELVVNNQKMAVP--------YRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI 2454
+A E+ +N +P +RP+ + L L + +LV + +
Sbjct: 504 KASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQL--NLQLVPTM----QLFM 557
Query: 2455 SLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVK 2500
L G GLCGN++ + +D SG + F N+++ +
Sbjct: 558 QLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQ 603
Score = 169 bits (429), Expect = 3e-41
Identities = 202/884 (22%), Positives = 325/884 (36%), Gaps = 163/884 (18%)
Query: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
VC G+ HY +FDG P C V + C A F + + G R
Sbjct: 732 VCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYE--DFNVQLRR-----GLVGSRPV 784
Query: 1990 EVYIDIYDAQVTLQKGH-RVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFD 2048
+ I + L+ + VLIN ++ LP G+ V+ S Y V+I++ + ++
Sbjct: 785 VTRVVIKAQGLVLEASNGSVLINGQREELPYSRT--GLLVEQSGDYIKVSIRLVLTFLWN 842
Query: 2049 GNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQ 2108
G +E+ Y + CG+CG+FN +P+ + + + + ++ Q
Sbjct: 843 GEDSALLELDPKYANQTCGLCGDFNG-------LPAFNEFYAHNARLTPLQFGNL----Q 891
Query: 2109 SLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN 2168
L +Q P + P+GNC + C L P +A+C + +D T +L CA
Sbjct: 892 KLDGPTEQCP-DPLPLPAGNCTDEE-----GICHRTLLGPAFAECHALVDSTAYLAACAQ 945
Query: 2169 TLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSC 2228
LC C + C G +P WR CP CP + C C+ +C
Sbjct: 946 DLCRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTC 1002
Query: 2229 WDLDGR--CEGAKVPSACAEGCICQPGYV------LSEDKCVPRSQCGCKDAHGGSIPLG 2280
+ CE C +GC C PG ++ C+P QC C HGG
Sbjct: 1003 SNPQRAQLCE-----DHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPC--THGGRTYSP 1055
Query: 2281 KSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYL 2340
+ ++ C+ C C+GG QC D CP CSV G
Sbjct: 1056 GTSFNTTCSS-CTCSGGLWQCQDLPCPG---------------------TCSVQGGAHIS 1093
Query: 2341 TFDGFSYRLQGRMTYVLIK-----TVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTV 2395
T+D Y L G +YVL K + VL E + L + N L+ V ++
Sbjct: 1094 TYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNEN---------CLKAVTLSL 1144
Query: 2396 YG--YKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVT-----DFELVVSFGG 2448
G +++QA + +N+ +P +TL+ + + +L+V
Sbjct: 1145 DGGDTAIRVQADGGVFLNSIYTQLPL---SAANITLFTPSSFFIVVQTGLGLQLLVQLVP 1201
Query: 2449 RKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLR- 2507
+ L ++G + GLCGN+++N+ +D SG + F N+W+ + A R
Sbjct: 1202 LMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARN 1261
Query: 2508 ---FPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTV 2564
P ++ E E + + C L DP F+ CH +
Sbjct: 1262 SFEDPCSLSVENE-----------------------NYARHWCSRLTDPNSAFSRCHSII 1298
Query: 2565 APEPFQEHCVLDLCSAQDPREQEELRCQVLSGH----------------GVSSRY----H 2604
P+PF +C+ D C+ + E+ C LS + GV ++Y
Sbjct: 1299 NPKPFHSNCMFDTCNCE---RSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCP 1355
Query: 2605 ISELYDTLPSILCQPGRPRGLRG----------PLRGRLRQHPRLCLQWHPEPPLADCGC 2654
S+ Y + CQP RGL P+ G P +C C
Sbjct: 1356 KSQRYAYVVD-ACQP-TCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPC 1413
Query: 2655 TSNGIYYQLGSSFLTEDCSQRCTCASSRI-----LLCEPFSCRAGEVCTLGNHTQGCFPE 2709
++G G + D C+C ++ L + C A V +++ P
Sbjct: 1414 YAHGTVLAPGE--VVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPG 1471
Query: 2710 SPCLQNPCQNDGQCREQGATFTCECEVGY---GGGLCMEPRDAP 2750
+ CL++ D C C C G G G C+ D P
Sbjct: 1472 AECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCP 1515
Score = 168 bits (425), Expect = 8e-41
Identities = 291/1110 (26%), Positives = 423/1110 (38%), Gaps = 153/1110 (13%)
Query: 531 PGTCPVKVLPELPPVSPVS-STG----PSETTGLTENPTISTKKPTVSIEKPSVTTEKPT 585
PGT +L EL + + STG PS T G P + T T P+ T+ K T
Sbjct: 4717 PGT--TWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATT----PTATSSKAT 4770
Query: 586 V---PKEKPTIP--TEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTI-PSEK 639
P+ T+P T T ST P + + T+P + T + TI PS
Sbjct: 4771 SSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTG-TLPEQTTTPVATMSTIHPSST 4829
Query: 640 P------TIPSEKPTIS--TEKPTVPTEEPTTP---TEETTTSMEEPVI-PTEKPSIPTE 687
P T+ + K T + T + P+ P T TE TT + PT PS
Sbjct: 4830 PETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPG 4889
Query: 688 KPSIPTEKPTISMEETII-STEKPTISPEKPTIPTEKPT-----IPT-EKSTISPEKPTT 740
I TE T + ST P+ +P I TE T +PT +T S + T
Sbjct: 4890 TTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATA 4949
Query: 741 PTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLT-IPTEKPTIPTEKPTIPTEKPTIST- 798
T + PT++ K T P+ SP T +P + T T T T P+ S
Sbjct: 4950 GTPHVSTTATTPTVTSSKAT-----PSSSPGTATALPALRSTATTPTATSFTAIPSSSLG 5004
Query: 799 ------EEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTI 852
+ TTPT T+ST PS E T+ T T+ TT +T + P P
Sbjct: 5005 TTWTRLSQTTTPT--ATMSTATPSSTPE--TVHTSTVLTATATTTGATGSVATPSSTPGT 5060
Query: 853 S--TEKPTIPTEKPTISPEKLTIPTEKLTIPTEKP-----TIPIEETTISTEKLTIPTEK 905
+ T+ PT T T +P + P LT PT P TI T +T T+ T
Sbjct: 5061 AHTTKVPTTTTTGFTATPS--SSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTT 5118
Query: 906 PTISPEKPTISTEKPTIPTEKPTIPTE-ETTISTEKLTIPTEKPTISPEKLTIPTEKPTI 964
T++ + +T T+ T + I TE TT +T T T + +P I TE TI
Sbjct: 5119 ATMTRATNSTATPSSTLGTTR--ILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTI 5176
Query: 965 STEK-PT--IPTEKLTIPT-EKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPH 1020
+T PT T T+ T P + T T+PT TA P S T V+
Sbjct: 5177 ATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTA--TASTVPSSSTVGTTRTPAVLPSS 5234
Query: 1021 APSTPMTSVILGTTTTSRSSTERCPPNARYES-CACPASC-----------KSPRPSCG- 1067
P+ +++V TT R + P++ + + C C A K+ R C
Sbjct: 5235 LPTFSVSTVSSSVLTTLRPTGF---PSSHFSTPCFCRAFGQFFSPGEVIYNKTDRAGCHF 5291
Query: 1068 -PLCRE---------GCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHC 1117
+C + C +P + S + + C + W NCT
Sbjct: 5292 YAVCNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGCDNAIPLRQVNETWTLENCTV-A 5350
Query: 1118 RCW-----------PGSRVEC-------QISQ----CGTHTVCQLKN-GQYGCHPYAGTA 1154
RC P + V C ++S C H C+ + G G P AG
Sbjct: 5351 RCVGDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECECVGGRGITPGAGI- 5409
Query: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPC----GNST----DPFFRVTAKNEEQGQE 1206
C ++G HY TFDG + F G CTY+L + GN + + + +A
Sbjct: 5410 -CSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAAR 5468
Query: 1207 GVSCLSKVYVTLP-ESTVTLLKGRRT-LVGGQQVTLPAIPSK-GVF---LGASGRFVELQ 1260
LS Y ++ TVT++ G+ L+ Q+ + + SK GV LG + V++
Sbjct: 5469 CPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIP 5528
Query: 1261 TEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSW 1320
G+ V ++G S + G CG N +D L+ DG+ A +++ +W
Sbjct: 5529 A-LGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTW 5587
Query: 1321 QTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFC--GRLVD--THGPFETCLLHVKAAS 1376
C + ++ SS P C L D F C V
Sbjct: 5588 LVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGP 5647
Query: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWR--EPHFCPMACPPNSKYSL 1434
FF++C+ D C +G + C + C+ G WR C + CPP Y
Sbjct: 5648 FFNACISDHC--RGRLEVPCQSLEAYAELCRARG-VCSDWRGATGGLCDLTCPPTKVYKP 5704
Query: 1435 CAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLEC-IPRSQCGCLHPAGSYFKVGE 1493
C P TC+S + E C C +L I C C+ P G GE
Sbjct: 5705 CGPIQPATCNSRNQSPQL-EGMAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGE 5763
Query: 1494 RWYKPGCKELCVC-ESNNRIRCQPWRCRAQ 1522
RW C+ CVC E + ++C+P C AQ
Sbjct: 5764 RWVS-NCQS-CVCDEGSVSVQCKPLPCDAQ 5791
Score = 153 bits (387), Expect = 2e-36
Identities = 116/493 (23%), Positives = 197/493 (39%), Gaps = 57/493 (11%)
Query: 1044 CPPNARYESCACPAS--CKSPRPS--CGPLCREGCVCNPGFL------FSDNHCIQASSC 1093
CP N +++ C P + C +P+ + C C +GC C PG + + C+ C
Sbjct: 985 CPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQC 1044
Query: 1094 NCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGT 1153
C + Y PG F+ C+ C G + C
Sbjct: 1045 PCTHGGRTYSPGTS-FNTTCSS----------------------CTCSGGLWQCQDLPCP 1081
Query: 1154 ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG-QEGVSCLS 1212
TC V G H T+D + + G C+Y+L++ C +S+ F V A+ + G + +CL
Sbjct: 1082 GTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSS---FTVLAELRKCGLTDNENCLK 1138
Query: 1213 KVYVTLP--ESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLR--VR 1268
V ++L ++ + + + LP + S F+ +QT GL+ V+
Sbjct: 1139 AVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQ 1198
Query: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
Q++V + + G++CGLCGN++ N +D L G N+W+
Sbjct: 1199 LVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKA----QA 1254
Query: 1329 ECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGF 1388
C + C S+++ +C RL D + F C + F +CM D C
Sbjct: 1255 ACANARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNC 1314
Query: 1389 QGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCP---MACPPNSKYSLCAKPCPDTCHS 1445
+ + LC +S+ C G + WR+ C CP + +Y+ C TC
Sbjct: 1315 ERSEDCLCAALSSYVHACAAKGVQLSDWRD-GVCTKYMQNCPKSQRYAYVVDACQPTCRG 1373
Query: 1446 -GFSGMFCSDRC--VEACECNPG-FVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCK 1501
+ + CS V+ C C G F+ C+P +C C + G+ GE + G
Sbjct: 1374 LSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPC-YAHGTVLAPGEVVHDEGA- 1431
Query: 1502 ELCVCESNNRIRC 1514
+C C + ++ C
Sbjct: 1432 -VCSC-TGGKLSC 1442
Score = 142 bits (357), Expect = 6e-33
Identities = 135/549 (24%), Positives = 206/549 (37%), Gaps = 113/549 (20%)
Query: 1844 CAESCECQKGHILSGTS-CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNIT 1902
C C C G + G+ C+ C C +Y P GE T CTC +
Sbjct: 1490 CVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKP-GE---TIRVDCNTCTCR-NRRWE 1544
Query: 1903 CFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVK-VC 1961
C C +G C G+ H+++FDG +S +C +L + C
Sbjct: 1545 CSHRLC-------------------LGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYC 1585
Query: 1962 HPAMALPFFKISAKHEK-EEGGTEAFRLHEVYIDIYDAQVT------------------- 2001
F+I ++ GT + ++++++ A
Sbjct: 1586 GDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGF 1645
Query: 2002 ------LQKGHRVLINSKQVTLPAISQIPG----VSVKSSSIYSIVNIKIGVQVKFDGNH 2051
LQ +L ++ T A+++ PG ++ I+ ++ G+ V +D
Sbjct: 1646 RQRLPPLQSYELIL---QEGTFKAVARGPGGDPPYKIRYMGIFLVIETH-GMAVSWDRKT 1701
Query: 2052 LLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLL 2111
+ I + Y G+VCG+CGNF+D ++ S V EF NSWK + PSC L
Sbjct: 1702 SVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWK---LSPSCPDAL 1758
Query: 2112 VDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPVWAQCASRIDLTPFLVDCAN- 2168
P C A R+ A+++C + L P +A C S++D T + C N
Sbjct: 1759 A------------PKDPCTANPFRKSWAQKQC-SILHGPTFAACRSQVDSTKYYEACVND 1805
Query: 2169 -TLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS-------SYTNC 2220
C+ GG + C A+ A+ C GL WR CPL C Y+ Y C
Sbjct: 1806 ACACDSGGDCECFCTAVAAYAQACHDAGLCVS-WRTPDTCPLFCDFYNPHGGCEWHYQPC 1864
Query: 2221 LPSCSPSCWDLDGRCEGAKVPSACAEGCI-----CQPGYVLSEDKCVPRSQCGCKDAHGG 2275
C +C + G C V EGC QP + + KCV +QCGC D G
Sbjct: 1865 GAPCLKTCRNPSGHC---LVDLPGLEGCYPKCPPSQPFFNEDQMKCV--AQCGCYDKDGN 1919
Query: 2276 SIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYG 2335
+G ++ + C CT IQC +S C ++ Y
Sbjct: 1920 YYDVGARVPTAENCQSCNCTPSGIQCA---------------HSLEACTCTYEDRTYSYQ 1964
Query: 2336 DPRYLTFDG 2344
D Y T DG
Sbjct: 1965 DVIYNTTDG 1973
Score = 139 bits (350), Expect = 4e-32
Identities = 130/493 (26%), Positives = 187/493 (37%), Gaps = 71/493 (14%)
Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIR 1513
DR AC +P V S P GC + A +V E W C + C +NR+
Sbjct: 5302 DRFQGACPTSPPPVSSAPLSSPSPAPGCDN-AIPLRQVNETWTLENCT-VARCVGDNRVV 5359
Query: 1514 CQPWRCRAQEFCGQQ-------------DGIYGCHAQ---------GAATCTASGDPHYL 1551
+ A C + D Y C + GA C+ G HY
Sbjct: 5360 LLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECECVGGRGITPGAGICSMWGGSHYS 5419
Query: 1552 TFDGALHHFMGTCTYVLTRPCWSR-------SQDSYFVVSATNENRGGILEVSYIKAVHV 1604
TFDG + F G CTYVL R +R + Y SAT ++H
Sbjct: 5420 TFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASAT--AAAAAARCPRALSIHY 5477
Query: 1605 TVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLL-----------YTNFG 1653
D+ +++ M++G L + Q V+ S N VL+ G
Sbjct: 5478 KSMDIVLTV-----TMVHGKEEGL-ILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALG 5531
Query: 1654 LQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPE 1713
+ V ++G S + G CG NN DD L+ D A + W +P+
Sbjct: 5532 VSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPD 5591
Query: 1714 SSEPGCFLVGGKPSSCQENSMADAW--------NKNCAILINPQGPFSQCHQVVPPQSSF 1765
S + GC+ G P + + + C ++++ F++CH +VPP F
Sbjct: 5592 SRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQ--VFAECHNLVPPGPFF 5649
Query: 1766 ASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRT--FCPMRCPPGSSYSPCSS 1823
+C+ C +G C+SL+AYA LC G WR T C + CPP Y PC
Sbjct: 5650 NACISDHC--RGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGP 5707
Query: 1824 PCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSC-VPLGQCGCTDPAGSYHPVGER 1882
P TC+S N P+ AE C C + IL + + C C P G GER
Sbjct: 5708 IQPATCNSRN---QSPQLEGMAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGER 5764
Query: 1883 WYTENTCTRLCTC 1895
W + + C C
Sbjct: 5765 WVSN---CQSCVC 5774
Score = 119 bits (297), Expect = 6e-26
Identities = 98/351 (27%), Positives = 144/351 (41%), Gaps = 56/351 (15%)
Query: 1042 ERCPPNARYESCACPAS--CKSPRPS--CGPLCREGCVCNPGFLFSD---NHCIQASSCN 1094
++CP N +Y C P + C + S C C GC C G + D C+ S C
Sbjct: 336 QKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCA 395
Query: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154
C YN Y PGA +S +CT +C C G R CQ C
Sbjct: 396 CVYNGAAYAPGAT-YSTDCT-NCTC-SGGRWSCQEVPC--------------------PG 432
Query: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG-QEGVSCLSK 1213
TC V G H+ TFDG+ + G C+Y+L +PC +S F V A+ G + +CL
Sbjct: 433 TCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSA---FTVLAELRRCGLTDSETCLKS 489
Query: 1214 VYVTLP-ESTVTLLKGRRTLVGGQQVT-LPAIPSKGVFLGASGRFVELQTEFGLRVRWD- 1270
V ++L TV ++K + Q T LP + S F+ QT GL++
Sbjct: 490 VTLSLDGAQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQL 549
Query: 1271 -GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQE 1329
QL++ ++ G+ CGLCGN++ +D L G N+++T
Sbjct: 550 VPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT----QAA 605
Query: 1330 CQKYQVVNSPSCDSSLQSS--MSGPGFCGRLV------------DTHGPFE 1366
C + C S++++ M P C LV +T GP E
Sbjct: 606 CPNIRNSFEDPCSLSVENAPRMGAPSACRTLVLALAAMLVVPQAETQGPVE 656
Score = 97.8 bits (242), Expect = 1e-19
Identities = 149/578 (25%), Positives = 208/578 (35%), Gaps = 61/578 (10%)
Query: 530 NPGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKE 589
N G CP P + SST P T LTE T +T T +T P +
Sbjct: 3550 NYGHCPST--PATSSTATPSST-PGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPK 3606
Query: 590 KPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPS--EKPTILTEKPTIPS----EKPTIP 643
T PT ++ K T S P + P + S K T + P IPS T+P
Sbjct: 3607 VLTSTATTPTATSSKAT-SSSSPRTATTLPVLTSTATKSTATSFTP-IPSFTLGTTGTLP 3664
Query: 644 SEKPTISTEKPTV-PTEEP-TTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISME 701
+ T T+ P+ P TT T T+ T S P+ P ++
Sbjct: 3665 EQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTA 3724
Query: 702 ETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKP-TISPEKPT 760
T + PT +P T T P+ +T++ +T T T T + T
Sbjct: 3725 ATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTAT 3784
Query: 761 TPT-----EKPTISPEKLT-IPTEKPTIPTEKPTIPTEKPTIS-----TEEPTTPTEETT 809
TPT P+ SP T +P + T T T T P+ S T T T T
Sbjct: 3785 TPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTAT 3844
Query: 810 ISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKP--TISTEKPTIPTEKPTIS 867
+ST PS E T+ T T+ TT +T + P P +T+ PT T T +
Sbjct: 3845 MSTATPSSTPE--TVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTAT 3902
Query: 868 PEKLTIPTEKLTIPTEKPTIPIEETTISTEK--LTIPTEKPTISPEKPTISTEKPTIPTE 925
P + P LT P + I TT T + P+ P + ++T T+ T
Sbjct: 3903 PS--SSPGTALT-----PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATG 3955
Query: 926 KPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKL---TIPTEK 982
P+ T S T P T + ++P P T T + T TE
Sbjct: 3956 SMATPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEP 4015
Query: 983 PTIPTEKPTIPT----EKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSR 1038
T+ + P T AL PHPS T SP +P T GT+ T+
Sbjct: 4016 STVTSHTPAATTSTTQHSTPALSSPHPSSRTT------ESPPSPGTTTPGHTRGTSRTTA 4069
Query: 1039 SSTERCPPNARYESCACPASCKSP------RPSCGPLC 1070
++T P+ S P+S S C P C
Sbjct: 4070 TAT----PSKTRTSTLLPSSPTSAPITTVVTTGCEPQC 4103
Score = 97.8 bits (242), Expect = 1e-19
Identities = 124/530 (23%), Positives = 195/530 (36%), Gaps = 84/530 (15%)
Query: 1825 CPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWY 1884
C C CP + P S LS S P GC D A V E W
Sbjct: 5295 CNQHCDIDRFQGACPTSPPPVSSAP------LSSPSPAP----GC-DNAIPLRQVNETWT 5343
Query: 1885 TENTCTRLCTCSVHN-----------NITCFQS-----TCKPNQICWALDGLLRCRAS-- 1926
EN CT + C N N+TC P+Q C D C
Sbjct: 5344 LEN-CT-VARCVGDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPC---DFHYECECECV 5398
Query: 1927 -------GVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHP-----AMALPFFKISA 1974
G G+C + G SHY +FDG++++ CT VL++ H ++ L +A
Sbjct: 5399 GGRGITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTA 5458
Query: 1975 KHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPG--------- 2025
R ++ D +T+ +++ K+ L QIP
Sbjct: 5459 SATAAAAAARCPRALSIHYKSMDIVLTV-----TMVHGKEEGLILFDQIPVSSGFSKNGV 5513
Query: 2026 -VSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIP-TTYYGKVCGMCGNFNDEEEDELMMP 2083
VSV ++ + +GV V F+G + + +P + ++ G CG + + D+ +
Sbjct: 5514 LVSVLGTTTMRVDIPALGVSVTFNG-QVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQR 5572
Query: 2084 SDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEA 2143
A S + +W D P P + + C+
Sbjct: 5573 DGTTAASCKDMAKTWLVP--DSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDL 5630
Query: 2144 ALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRN 2203
L + V+A+C + + PF C + C G + CQ+L+A+ C+++G+ WR
Sbjct: 5631 ML-SQVFAECHNLVPPGPFFNACISDHCR--GRLEVPCQSLEAYAELCRARGVCSD-WRG 5686
Query: 2204 SS--FCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDK- 2260
++ C L CP Y C P +C + R + ++ AEGC C +L
Sbjct: 5687 ATGGLCDLTCPPTKVYKPCGPIQPATC---NSRNQSPQL-EGMAEGCFCPEDQILFNAHM 5742
Query: 2261 --CVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGG--AIQCGDFRC 2306
CV C C G G+ WVS+ + CVC G ++QC C
Sbjct: 5743 GICV--QACPCVGPDGFPKFPGERWVSN--CQSCVCDEGSVSVQCKPLPC 5788
Score = 81.3 bits (199), Expect = 1e-14
Identities = 115/443 (25%), Positives = 164/443 (37%), Gaps = 81/443 (18%)
Query: 661 PTTPTEETTTSMEEPVIPTEKPS---IPTEKPSIPTEKPTISMEETIISTEKPTISPEKP 717
P+TP +T +P+ P I TE + T + T ST P+
Sbjct: 4702 PSTPATSSTA------MPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVL 4755
Query: 718 TIPTEKPTIPTEKSTISPEKPTTPTEKPTI-------------PTEKPTIS-----PEKP 759
T P PT + K+T S P T T P + P T+ PE+
Sbjct: 4756 TSPATTPTATSSKAT-SSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQT 4814
Query: 760 TTP-TEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTE-KPSI 817
TTP TI P T T+ T K T T + T ST P++ T I TE +
Sbjct: 4815 TTPVATMSTIHPSSTPETTHTSTVLTTKAT--TTRATSSTSTPSSTPGTTWILTELTTAA 4872
Query: 818 PMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTE- 876
T PT +++ T I TE T T +T T T P+ +P I TE
Sbjct: 4873 TTTAATGPTATPSSTPGTTWILTELTT------TATTTASTGSTATPSSTPGTTWILTEP 4926
Query: 877 ----KLTIPT-EKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPT---IPTEKPT 928
+T+PT T + T T ++ PT++ K T S+ T +P + T
Sbjct: 4927 STTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRST 4986
Query: 929 IPTEETT-------------------ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKP 969
T T +T T+ T P+ +PE T+ T +T
Sbjct: 4987 ATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE--TVHTSTVLTATATT 5044
Query: 970 TIPTEKLTIPTEKP--TIPTEKPTIPTEKL---------TALRPPHPSPTATGLAALVMS 1018
T T + P+ P T+ PT T TAL PP +P +T + + +
Sbjct: 5045 TGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTTTPMST--MSTIHT 5102
Query: 1019 PHAPSTPMTSVILGTTTTSRSST 1041
P T TS +L TT T +T
Sbjct: 5103 SSTPETTHTSTVLTTTATMTRAT 5125
Score = 79.7 bits (195), Expect = 4e-14
Identities = 135/533 (25%), Positives = 191/533 (35%), Gaps = 51/533 (9%)
Query: 549 SSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIP 608
+S P+ TTG T++ T + P S S TTE P P T P S T
Sbjct: 4521 TSHTPAATTGTTQHSTPALSSPHPS----SRTTESP--PSPGTTTPGHTTATSRTTATAT 4574
Query: 609 SEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEET 668
K + P+ P+ P +T T E SE S P + T +
Sbjct: 4575 PSKTRTSTLLPSSPTSAP--ITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIR 4632
Query: 669 TTSMEEPVIPTEKPSIPTEKPSIPT----EKPTISMEETIISTEKPTISPEKPTIPTEK- 723
P +P +P + S++ ++ + + K E
Sbjct: 4633 AAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIR 4692
Query: 724 ---------PTIPTEKSTISPEKP--TTPTEKPTIPTEKPTISPEKPTTPTEKPTISP-- 770
P+ P ST P TT T T S TP+ P +P
Sbjct: 4693 VFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPP 4752
Query: 771 EKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETT 830
+ LT P PT + K T + T +T T T T ST P+ TL T T
Sbjct: 4753 KVLTSPATTPTATSSKATSSSSPRTATTLPVLTST--ATKSTATSVTPIPSSTLGTTGTL 4810
Query: 831 TSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPT---I 887
T ++T P P +T T+ T K T T T + P+ P I
Sbjct: 4811 PEQTTTPVATMSTIHPSSTPE-TTHTSTVLTTKATT-----TRATSSTSTPSSTPGTTWI 4864
Query: 888 PIEETTISTEKL-TIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLT-IPT 945
E TT +T T PT P+ +P I TE T T + + T ST T I T
Sbjct: 4865 LTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILT 4924
Query: 946 EKPTISPEKLTIPT-EKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEK-----LTA 999
E T + +T+PT T S+ + T T ++ PT+ + K T + L A
Sbjct: 4925 EPSTTAT--VTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPA 4982
Query: 1000 LRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYES 1052
LR +PTAT A+ S S T L TTT ++ P++ E+
Sbjct: 4983 LRSTATTPTATSFTAIPSS----SLGTTWTRLSQTTTPTATMSTATPSSTPET 5031
Score = 79.3 bits (194), Expect = 5e-14
Identities = 127/519 (24%), Positives = 183/519 (35%), Gaps = 79/519 (15%)
Query: 468 LLGSPAGSPPIPLWKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFI 527
+L S A +P K S P T+ T+P L + + T+ F
Sbjct: 3607 VLTSTATTPTATSSKATSSSSP---RTATTLPV-------LTSTATKSTATSFTPIPSFT 3656
Query: 528 LINPGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTV-----SIEKPSVTTE 582
L GT P + P++ +S+ PS T T T+ T K T S+ PS T
Sbjct: 3657 LGTTGTLPEQTTT---PMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPG 3713
Query: 583 KPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM------PSEKPTIP-------------- 622
+ E T T T +T PS P PS T+
Sbjct: 3714 TTWILTELTTAATT--TAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRA 3771
Query: 623 -----------SEKPTILTEKPTIPSEKP----TIPSEKPTISTEKPTVPTEEPTTPTEE 667
+ PT+++ + T PS P +P+ + T +T T T P++
Sbjct: 3772 TAGTLKVLTSTATTPTVISSRAT-PSSSPGTATALPALRSTATTPTATSVTAIPSSSLGT 3830
Query: 668 TTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP------T 721
T + + PT S T S P T ++ T +T + T S P+ T
Sbjct: 3831 AWTRLSQTTTPTATMSTATPS-STPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTT 3889
Query: 722 EKPTIPTEKSTISPEK-PTTPTEKPT-IPTEKPTISPEKPTTPTEKPTISPEKLTIPTEK 779
+ PT T T +P P T P I T + TP+ P + + T
Sbjct: 3890 KVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTT 3949
Query: 780 PTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKP-TLPTEET--TTSVEET 836
T+ T P+ S T P TT +T S+P P T+ T T T+ + T
Sbjct: 3950 TTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGT 4009
Query: 837 TISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTIST 896
T TE T+ P +T T P +S P+ + T P T T
Sbjct: 4010 THITEPSTVTSHTPAATTS--TTQHSTPALSSPH---PSSRTTESPPSPGTTTPGHTRGT 4064
Query: 897 EKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETT 935
+ T T +P K ST P+ PT P I T TT
Sbjct: 4065 SRTT-----ATATPSKTRTSTLLPSSPTSAP-ITTVVTT 4097
Score = 79.0 bits (193), Expect = 6e-14
Identities = 104/395 (26%), Positives = 151/395 (38%), Gaps = 39/395 (9%)
Query: 554 SETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPT-EKPTISTEKPTIPSEKP 612
+E+TG T P+ ST T + +PS T TV T+PT T S+ + T +
Sbjct: 4231 TESTGSTATPS-STPGTTWILTEPSTTA---TV-----TVPTGSTATASSTQATAGTPHV 4281
Query: 613 NMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSM 672
+ + PT+ S K T + P +P+ + T +T T T P++ T T +
Sbjct: 4282 STTATTPTVTSSKATPFSS----PGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRL 4337
Query: 673 EEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP------TEKPTI 726
+ PT S T S P T ++ T +T + T S P+ T+ PT
Sbjct: 4338 SQTTTPTATMSTATPS-STPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTT 4396
Query: 727 PTEKSTISPEKPTTPTEKPTI---PTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIP 783
T T++P P + T PT S TP+ P + + T T+
Sbjct: 4397 TTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGST-VTPSSVPGTTHTPTVLTTTTTTVA 4455
Query: 784 TEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKL 843
T P+ S T P TT +T S+ P TS T+ T +
Sbjct: 4456 TGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHT-VRTAWTSATSGTLGTTHI 4514
Query: 844 TIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEET---TISTEKLT 900
T P T ++ P T S L+ P + TE P P T T +T + T
Sbjct: 4515 TEPS---TGTSHTPAATTGTTQHSTPALSSPHPS-SRTTESPPSPGTTTPGHTTATSRTT 4570
Query: 901 IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETT 935
T +P K ST P+ PT P I T TT
Sbjct: 4571 A-----TATPSKTRTSTLLPSSPTSAP-ITTVVTT 4599
Score = 75.5 bits (184), Expect = 7e-13
Identities = 102/403 (25%), Positives = 148/403 (36%), Gaps = 46/403 (11%)
Query: 689 PSIPTEKPTISMEET-----IISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTE 743
PS P T + T I++ T + T T PT T ++ P+ TT
Sbjct: 2579 PSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPT-STLRTAPPPKVLTTTAT 2637
Query: 744 KPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTT 803
PT+ + K T S P T T P + T PT P ++ T +S + TT
Sbjct: 2638 TPTVTSSKATPS-SSPGTATALPALR-STATTPTATSVTPIPSSSLGTTWTRLS--QTTT 2693
Query: 804 PTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKP--TISTEKPTIPT 861
PT T+ST PS E T T T+ TT +T + P P +T+ PT T
Sbjct: 2694 PT--ATMSTATPSSTPE--TAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTT 2749
Query: 862 EKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEK--LTIPTEKPTISPEKPTISTEK 919
T +P + P LT P + I TT T + P+ P + ++T
Sbjct: 2750 TGFTATPS--SSPGTALT-----PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTT 2802
Query: 920 PTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKP------TISTEKPTIPT 973
T+ T P+ T S T P + ++P P S + T
Sbjct: 2803 TTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGT 2862
Query: 974 EKLTIPTEKPTIPTEKPTIPTEKLT-ALRPPHPSPTATGLAALVMSPHAPSTPMTSVILG 1032
+T P+ + T T+ T AL PHPS T +P +P T+
Sbjct: 2863 THITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTT---------ESPPSPGTTTPGH 2913
Query: 1033 TTTTSRSSTERCPPNARYESCACPASCKSP-----RPSCGPLC 1070
TT TSR++ P R + + +P C P C
Sbjct: 2914 TTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQC 2956
Score = 75.5 bits (184), Expect = 7e-13
Identities = 107/397 (26%), Positives = 147/397 (37%), Gaps = 48/397 (12%)
Query: 682 PSIP-TEKPSIPTEKP-TISMEETIISTEKPTISPEKPTIPTEKP-TIPTEKSTISPEKP 738
PS P T ++P+ P T + + +T T S P+ P T P P+
Sbjct: 4702 PSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPP------PKVL 4755
Query: 739 TTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTIST 798
T+P PT + K T S P T T P LT K T + P + T T
Sbjct: 4756 TSPATTPTATSSKAT-SSSSPRTATTLPV-----LTSTATKSTATSVTPIPSSTLGTTGT 4809
Query: 799 EEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKP-------- 850
T T T+ST PS E T T T+ TT +T + P P
Sbjct: 4810 LPEQTTTPVATMSTIHPSSTPE--TTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTE 4867
Query: 851 ---TISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKP- 906
+T T PT P+ +P I TE T T + T ST T +P
Sbjct: 4868 LTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPS 4927
Query: 907 -TISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLT-IPTEKPTI 964
T + PT ST + P TT +T +T P+ SP T +P + T
Sbjct: 4928 TTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTA 4987
Query: 965 STEKPT----IPTEKL----------TIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTAT 1010
+T T IP+ L T PT T+ T P+ E + + T T
Sbjct: 4988 TTPTATSFTAIPSSSLGTTWTRLSQTTTPT--ATMSTATPSSTPETVHTSTVLTATATTT 5045
Query: 1011 GLAALVMSPHA-PSTPMTSVILGTTTTSRSSTERCPP 1046
G V +P + P T T+ + TTTT ++T P
Sbjct: 5046 GATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSP 5082
Score = 73.6 bits (179), Expect = 3e-12
Identities = 106/417 (25%), Positives = 150/417 (35%), Gaps = 38/417 (9%)
Query: 530 NPGTCPVKVLPELPPVSPVSSTGPSETTGLTE-NPTISTKKPTVSIEKPSVTTEKPTVPK 588
N G CP P + SST P T LTE T +T + T S PS T +
Sbjct: 3048 NYGHCPST--PATSSTAMPSST-PGTTWILTELTTTATTTESTGSTATPSSTPGTTWILT 3104
Query: 589 EKPT-----IPT-EKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTI 642
E T +PT T S+ + T + + + PT+ S K T + P +
Sbjct: 3105 EPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSS----PGTATAL 3160
Query: 643 PSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEE 702
P+ + T +T T T P++ T T + + PT S T P+ P
Sbjct: 3161 PALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTAT-----PSSTPETVHTS 3215
Query: 703 TIISTEKPTISPE-KPTIPTEKP-TIPTEK--STISPEKPTTPTEKPTIPTEKPTISPEK 758
T+++T T P+ P T T K +T + TP+ P P
Sbjct: 3216 TVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTT 3275
Query: 759 PTTPTEKPTISPEKLTIPTEKPTIPTEKPTI--------PTEKPTISTEEPTTPTEETTI 810
T T T++P + T PT+ T T P+ S T P TT
Sbjct: 3276 TTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTA 3335
Query: 811 STEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEK 870
+T S+ P TS T+ T +T P T ++ P T S
Sbjct: 3336 TTHGRSLSPSSPHT-VRTAWTSATSGTLGTTHITEPS---TGTSHTPAATTGTTQHSTPA 3391
Query: 871 LTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKP 927
L+ P + TE P P T T + T T +P K ST P+ PT P
Sbjct: 3392 LSSPHPS-SRTTESPPSPGTTTPGHTRATSRTTA--TATPSKTRTSTLLPSSPTSAP 3445
Score = 72.4 bits (176), Expect = 6e-12
Identities = 119/490 (24%), Positives = 175/490 (35%), Gaps = 53/490 (10%)
Query: 580 TTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEK 639
TT PT E T T + ST +PT P + P + PT L+E T P
Sbjct: 2301 TTPPPTTELETATTTTTQALFSTPQPT---SSPGLTRAPPASTTAVPT-LSEGLTSPRYT 2356
Query: 640 PTIPSEKPTISTEKPTVP--TEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPT 697
T+ T +T PT P + EPT P T+T +P S+ T +PS P PT
Sbjct: 2357 STL----GTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQP---PT 2409
Query: 698 ISMEETIISTEKPT----ISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPT 753
++ S +PT + ++P + PT+ +E ST E T TE T
Sbjct: 2410 LAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTE--------TT 2461
Query: 754 ISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPT---------TP 804
+SP TT ++ T K TE + PT + T E P
Sbjct: 2462 MSPLTNTTTSQGTTRCQPKCEW-TE--WFDVDFPTSGVAGGDMETFENIRAAGGKMCWAP 2518
Query: 805 TEETTISTEKPSIPMEKP----TLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIP 860
+ P + +++ T E T E + + + +
Sbjct: 2519 KSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHC 2578
Query: 861 TEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKP 920
P S T T KPT TT ST PT +P ++T
Sbjct: 2579 PSTPATSSTATPSSTPGTTWILTKPT-TTATTTASTGSTATPTSTLRTAPPPKVLTTTAT 2637
Query: 921 TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLT 977
T PT+ + + T S+ T +P + T + T T P+ S + T
Sbjct: 2638 T-----PTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTT 2692
Query: 978 IPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHA-PSTPMTSVILGTTTT 1036
PT T+ T P+ E + T TG V +P + P T T+ + TTTT
Sbjct: 2693 TPT--ATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTT 2750
Query: 1037 SRSSTERCPP 1046
++T P
Sbjct: 2751 GFTATPSSSP 2760
Score = 70.9 bits (172), Expect = 2e-11
Identities = 99/396 (25%), Positives = 134/396 (33%), Gaps = 39/396 (9%)
Query: 540 PELPPVSPVSSTGPSETTGLT-----ENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIP 594
P P S S+ PS T G T T +T T S P+ T PK T
Sbjct: 2579 PSTPATS--STATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTA 2636
Query: 595 TEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKP 654
T PT+++ K T PS P + P + S T PT S P S+
Sbjct: 2637 TT-PTVTSSKAT-PSSSPGTATALPALRSTATT------------PTATSVTPIPSSSLG 2682
Query: 655 TVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISP 714
T T T T T S P E T + T T ST +
Sbjct: 2683 TTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTT 2742
Query: 715 EKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLT 774
+ PT T T S + P T PT + + TP+ P +
Sbjct: 2743 KVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGS-----TVTPSSIPGTTHTATV 2797
Query: 775 IPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKP-TLPTEET--TT 831
+ T T+ T P+ S T P T +T S+P P T+ T T T+
Sbjct: 2798 LTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATS 2857
Query: 832 SVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEE 891
+ TT TE T+ T++ T P +S P+ + T P
Sbjct: 2858 GILGTTHITEPSTVTSH--TLAATTGTTQHSTPALSSPH---PSSRTTESPPSPGTTTPG 2912
Query: 892 TTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKP 927
T +T + T T +P K ST P+ PT P
Sbjct: 2913 HTTATSRTT-----ATATPSKTRTSTLLPSSPTSAP 2943
Score = 65.5 bits (158), Expect = 7e-10
Identities = 92/366 (25%), Positives = 123/366 (33%), Gaps = 59/366 (16%)
Query: 549 SSTGPSETTG----LTENPTISTKK-PTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTE 603
S+ PS T G LTE T +T PT S S T P T T PT+++
Sbjct: 4236 STATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATT--PTVTSS 4293
Query: 604 KPTIPSEKPNMPSEKPTIPSEKPT-ILTEKPTIPSEK-------------PTIPSEKPTI 649
K T P P + P + S T T IPS PT T
Sbjct: 4294 KAT-PFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATP 4352
Query: 650 STEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP--TEKPSIPTEKPTISMEETIIST 707
S+ T T T T TT + P+ P T+ P+ T T++ + +
Sbjct: 4353 SSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTA 4412
Query: 708 EKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTI-PTEKPTISPEKPTTPTEKP 766
P + T PT T ST++P T PT+ T T++ TP+
Sbjct: 4413 RTPPVWISTTTTPT------TSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSST 4466
Query: 767 TISPEKLTIPTEKPTIPTEKPTIPTEKP----------------TISTEEPTTPTEETTI 810
S T P T T ++ P T EP+T T T
Sbjct: 4467 QTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPA 4526
Query: 811 ST------EKPSIPMEKPTLPTEE------TTTSVEETTISTEKLTIPMEKPTISTEKPT 858
+T P++ P+ T E TTT T S T K ST P+
Sbjct: 4527 ATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPS 4586
Query: 859 IPTEKP 864
PT P
Sbjct: 4587 SPTSAP 4592
Score = 62.4 bits (150), Expect = 6e-09
Identities = 129/569 (22%), Positives = 194/569 (34%), Gaps = 88/569 (15%)
Query: 546 SPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKP 605
S V+S P+ TT T++ T + P S S TTE P P T P S
Sbjct: 4016 STVTSHTPAATTSTTQHSTPALSSPHPS----SRTTESP--PSPGTTTPGHTRGTSRTTA 4069
Query: 606 TIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPT 665
T K + P+ P+ P +T T E SE S P + T +
Sbjct: 4070 TATPSKTRTSTLLPSSPTSAP--ITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYS 4127
Query: 666 EETTTSMEEPVIPTEKPSIPTEKPSIPTEK----PTISMEETIISTEKPTISPEKPTIPT 721
P +P +P + S++ ++ + + K
Sbjct: 4128 NIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNY 4187
Query: 722 EK----------PTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPE 771
E P+ P ST +P +TP + T + + T T P+ +P
Sbjct: 4188 EIRVFCCNYGHCPSTPATSSTATPS--STPGTTWILTKLTTTATTTESTGSTATPSSTPG 4245
Query: 772 KLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTT 831
I TE T T T+PT +T T +T + T T +T
Sbjct: 4246 TTWILTEPSTTATV--TVPTG---------STATASST-----------QATAGTPHVST 4283
Query: 832 SVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLT-IPTEKLTIPTEKPTIPIE 890
+ T+++ K T P P +T P + + T + T IP+ L + +
Sbjct: 4284 TATTPTVTSSKAT-PFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTR----LS 4338
Query: 891 ETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTI 950
+TT T T+ T P+ +PE ST T T + T ST T+ PT
Sbjct: 4339 QTTTPTA--TMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTT 4396
Query: 951 SPEKLTI-PTEKP--------------TISTEKPTIPTEKLTIPTEKPTI-PTEKPTIPT 994
+ T+ P+ P T +T T+ + T PT+ T T+ T
Sbjct: 4397 TTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVAT 4456
Query: 995 EKL-----------TALRPPHPSPTAT--GLAALVMSPHAPSTPMTSVILGTTTTSR--- 1038
+ T PP P+ TAT G + SPH T TS GT T+
Sbjct: 4457 GSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITE 4516
Query: 1039 --SSTERCPPNARYESCACPASCKSPRPS 1065
+ T P + + SP PS
Sbjct: 4517 PSTGTSHTPAATTGTTQHSTPALSSPHPS 4545
Score = 58.9 bits (141), Expect = 7e-08
Identities = 92/360 (25%), Positives = 130/360 (36%), Gaps = 64/360 (17%)
Query: 756 PEKP-TTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEK 814
P P T+ T P+ +P I TE T T T + T ST P++ T I TE
Sbjct: 3053 PSTPATSSTAMPSSTPGTTWILTELTTTAT------TTESTGSTATPSSTPGTTWILTEP 3106
Query: 815 PSIPMEKPTLPTEETTT-SVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLT- 872
+ T+PT T T S + T T ++ PT+++ K T P SP T
Sbjct: 3107 STTATV--TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT-----PFSSPGTATA 3159
Query: 873 IPTEKLTIPTEKPT----IPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPT 928
+P + T T T IP + +L+ T PT + T S+ T+ T
Sbjct: 3160 LPALRSTATTPTATSFTAIPSSSLGTTWTRLS-QTTTPTATMSTATPSSTPETVHTSTVL 3218
Query: 929 IPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIP-----TEKP 983
T TT +T + P+ P + + T + + P T+P T P
Sbjct: 3219 TTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTP 3278
Query: 984 T----------IP--TEKPTIPTEKLTAL-------------------RPPHPSPTAT-- 1010
T IP T PT+ T T + PP P+ TAT
Sbjct: 3279 TTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTH 3338
Query: 1011 GLAALVMSPHAPSTPMTSVILGTTTTSR-----SSTERCPPNARYESCACPASCKSPRPS 1065
G + SPH T TS GT T+ + T P + + SP PS
Sbjct: 3339 GRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPS 3398
Score = 57.4 bits (137), Expect = 2e-07
Identities = 100/431 (23%), Positives = 142/431 (32%), Gaps = 91/431 (21%)
Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
CS +GD Y TFDG +R G YV + E L G P +
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRP-----VVTR 787
Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSF--GG 2448
V+ G ++ G +++N Q+ +PY L V G Y+ LV++F G
Sbjct: 788 VVIKAQGLVLEASNG-SVLINGQREELPYS-RTGLLVEQSGD--YIKVSIRLVLTFLWNG 843
Query: 2449 RKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRF 2508
+A++ L Y GLCG+++ + A L FGN ++
Sbjct: 844 EDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ-FGNLQKLDGPTEQCPD 902
Query: 2509 PRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEP 2568
P +PA C+ E+ + R L P FA CH V
Sbjct: 903 PLPLPA-----------------GNCTDEEGICH-----RTLLGPA--FAECHALVDSTA 938
Query: 2569 FQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRPRGLRGP 2628
+ C DLC RC + + G+PR R P
Sbjct: 939 YLAACAQDLC-----------RCPTCP---------CATFVEYSRQCAHAGGQPRNWRCP 978
Query: 2629 LRGRLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEP 2688
PR C PL + +Q S T+ CS R LCE
Sbjct: 979 -----ELCPRTC-------PL--------NMQHQECGSPCTDTCSN-----PQRAQLCED 1013
Query: 2689 FS-----CRAGEVCTLGNHT--QGCFPESPCLQNPCQNDGQCREQGATFTCECEVGYGGG 2741
C G CT+ + GC P C PC + G+ G +F C G
Sbjct: 1014 HCVDGCFCPPGRSCTVLDDITHSGCLPLGQC---PCTHGGRTYSPGTSFNTTCSSCTCSG 1070
Query: 2742 LCMEPRDAPPP 2752
+ +D P P
Sbjct: 1071 GLWQCQDLPCP 1081
Score = 57.4 bits (137), Expect = 2e-07
Identities = 131/551 (23%), Positives = 184/551 (33%), Gaps = 69/551 (12%)
Query: 530 NPGTCPVKVLPEL-----PPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKP 584
+PGT LP L P + + PS + G T T PT ++ + ++
Sbjct: 4300 SPGTATA--LPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE 4357
Query: 585 TVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPS 644
T T T +T PS P ++ PT T T+ PS
Sbjct: 4358 TAHTSTVLTTTATTTRATGSVATPSSTPGTAHT-----TKVPTTTTTGFTVT------PS 4406
Query: 645 EKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
P + T P TT T T+ S P PT + T T SM
Sbjct: 4407 SSPGTAR---TPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPS 4463
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKP-------------TTPTEKPTIPTEK 751
ST+ S T P T T ++SP P T T T P+
Sbjct: 4464 SSTQ---TSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTG 4520
Query: 752 PTISPEKPTTPTEKPT---ISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEET 808
+ +P T T+ T SP + TE P P+ T P S T +T
Sbjct: 4521 TSHTPAATTGTTQHSTPALSSPHPSSRTTESP--PSPGTTTPGHTTATSRTTATATPSKT 4578
Query: 809 TISTEKPSIPMEKPTLPTEETTTSVEETTISTEKL--TIPMEKPTIS--TEKPTIPTEKP 864
ST PS P P T TT E +E L + PM P+ I
Sbjct: 4579 RTSTLLPSSPTSAPI--TTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGG 4636
Query: 865 TISPEKLTIPTEKLTIPTEKPTIPIEE----TTISTEKLTIPTEKPTISPEKPTISTE-- 918
+ + L + +P +P+ E S + + + + K + E
Sbjct: 4637 AVCEQPLGLECR----AQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIR 4692
Query: 919 --------KPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPT 970
P+ P T T +T LT T T + T T P+ ST
Sbjct: 4693 VFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTAS--TGSTATPS-STPGTA 4749
Query: 971 IPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVI 1030
P + LT P PT + K T + TA P + TAT A ++P ST T+
Sbjct: 4750 PPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGT 4809
Query: 1031 LGTTTTSRSST 1041
L TT+ +T
Sbjct: 4810 LPEQTTTPVAT 4820
Score = 55.8 bits (133), Expect = 6e-07
Identities = 115/570 (20%), Positives = 186/570 (32%), Gaps = 114/570 (20%)
Query: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPL---G 2280
C+ C D+D R +GA C P V S P GC +A IPL
Sbjct: 5295 CNQHC-DID-RFQGA---------CPTSPPPVSSAPLSSPSPAPGCDNA----IPLRQVN 5339
Query: 2281 KSWVSSGCTEK--------------------CVCTGGAIQCGDFRCPSGSHCQLTSDNSN 2320
++W CT CV I+ D P H + +
Sbjct: 5340 ETWTLENCTVARCVGDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECECVG 5399
Query: 2321 SNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLL-------- 2372
++ + CS++G Y TFDG SY +G TYVL++ + + L
Sbjct: 5400 GRGITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTAS 5459
Query: 2373 -VEGRNKMDPPRS------SIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL 2425
PR+ S+ + +T V+G + L ++ + ++ + N L
Sbjct: 5460 ATAAAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGL-----ILFDQIPVSSGFSKNGVL 5514
Query: 2426 RVTLWGQRLYL-VTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSG 2484
L + + + + V+F G+ S++ G CG N+++D + G
Sbjct: 5515 VSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDG 5574
Query: 2485 ALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNST 2544
+ +W V + ++G A G T S +P T
Sbjct: 5575 TTAASCKDMAKTWLVP------------DSRKDGCWAPTG--TPPTASPAAPVSSTPTPT 5620
Query: 2545 QA-----CRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSA--QDPREQEELRCQVLSGH 2597
C ++ FA CH V P PF C+ D C + P + E ++
Sbjct: 5621 PCPPQPLCDLMLSQ--VFAECHNLVPPGPFFNACISDHCRGRLEVPCQSLEAYAELCRAR 5678
Query: 2598 GVSSRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPL----ADCG 2653
GV S + + L + C P + GP++ P C + P L C
Sbjct: 5679 GVCSDWRGAT--GGLCDLTCPPTKVYKPCGPIQ------PATCNSRNQSPQLEGMAEGCF 5730
Query: 2654 CTSNGIYYQLGSSFLTEDC-------------------SQRCTCASSRI-LLCEPFSCRA 2693
C + I + + C Q C C + + C+P C A
Sbjct: 5731 CPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDA 5790
Query: 2694 GEVCTLGNHTQGCFPESPCLQNPCQNDGQC 2723
N P +NPC + C
Sbjct: 5791 QGQPPPCNRPGFVTVTRPRAENPCCPETVC 5820
Score = 52.4 bits (124), Expect = 6e-06
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 15/177 (8%)
Query: 543 PPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPK--EKPTIPTEKPTI 600
PP + + + + T L P T P ++ P+ TT PT+ + P + T
Sbjct: 2304 PPTTELETATTTTTQALFSTPQ-PTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTA 2362
Query: 601 STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTI----PSEKPTISTEKPTV 656
+T PT P+ S +PT+P + L + +P ++ PS+ PT++ PT
Sbjct: 2363 TTGGPTTPAG-----STEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLA---PTT 2414
Query: 657 PTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTIS 713
PT +T+ +EP+ + P++ +E + E T E T+ T S
Sbjct: 2415 MATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTS 2471
Score = 52.0 bits (123), Expect = 8e-06
Identities = 87/390 (22%), Positives = 134/390 (34%), Gaps = 69/390 (17%)
Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
CS +G Y TFDG +R G YV + E L + P L
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPT-----LSR 135
Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRK 2450
V+ V G +QL G ++VN + +P+ + L + + LV+ +
Sbjct: 136 VLMKVDGVVIQLTKG-SVLVNGHPVLLPFSQSGVL-IQQSSSYTKVEARLGLVLMWNHDD 193
Query: 2451 NAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNT----FGNSWEVKTEDALL 2506
+ ++ L + Y GLCG++ N M + S L+ N FGN K +D
Sbjct: 194 SLLLELDTKYANKTCGLCGDF-----NGMPVVSELLSHNTKLTPMEFGNLQ--KMDDPTE 246
Query: 2507 RFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAP 2566
+ +P P + S C L Q F+ C V
Sbjct: 247 QCQDPVP---------------------EPPRNCSTGFGICEELLHGQ-LFSGCVALVDV 284
Query: 2567 EPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRPRGL- 2625
+ E C DLC +D + C L+ + + D C P +
Sbjct: 285 GSYLEACRQDLCFCED-TDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQ 343
Query: 2626 ----RGPLRGRL--RQHPRLCLQ------WHPE------------PPLADCGCTSNGIYY 2661
R P ++H R C + PE P++ C C NG Y
Sbjct: 344 YHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAY 403
Query: 2662 QLGSSFLTEDCSQRCTCASSRILLCEPFSC 2691
G+++ T DC+ CTC+ R C+ C
Sbjct: 404 APGATYST-DCT-NCTCSGGR-WSCQEVPC 430
Score = 50.4 bits (119), Expect = 2e-05
Identities = 53/189 (28%), Positives = 76/189 (40%), Gaps = 27/189 (14%)
Query: 882 TEKPTIPIEETTISTEKLTIPTEKPTISP----EKPTISTEKPTIPTEKPTIPTEETTIS 937
T PT +E T +T + T +PT SP P +T PT+ +E T P +T+
Sbjct: 2302 TPPPTTELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTL-SEGLTSPRYTSTLG 2360
Query: 938 TEKLTIPT-----EKPTIS-------PEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTI 985
T PT +PT+ P + +P ++ T +P+ P PT PT
Sbjct: 2361 TATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQP------PTLAPTT 2414
Query: 986 PTEKPTIPT-EKLTALRPPHPSPTATGLAA-LVMSPHAPSTPMTSVILG--TTTTSRSST 1041
PT TA + P + A L + L S STP T + T TT+ T
Sbjct: 2415 MATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGT 2474
Query: 1042 ERCPPNARY 1050
RC P +
Sbjct: 2475 TRCQPKCEW 2483
Score = 42.4 bits (98), Expect = 0.007
Identities = 95/433 (21%), Positives = 140/433 (32%), Gaps = 57/433 (13%)
Query: 759 PTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTI----STEEPTTPTEETTIS--- 811
P P+ P SP+ + +P +PT T TEK T+ S T +T S
Sbjct: 2124 PCGPSPAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGP 2183
Query: 812 -TEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEK-PTISTEKPTIPTEKPTISPE 869
T PS P P + T +E +E+L +E I + + I +
Sbjct: 2184 VTVTPSAPGTTTCQPRCQWTEWFDEDYPKSEQLGGDVESYDKIRAAGGHLCQQPKDIECQ 2243
Query: 870 KLTIPTEKLTIPTEKPTIPI---------EETTISTEKLTIPTEKPTISPE--KPTISTE 918
+ P L +K + E+ + S + + +T
Sbjct: 2244 AESFPNWTLAQVGQKVHCDVHFGLVCRNWEQEGVFKMCYNYRIRVLCCSDDHCRGRATTP 2303
Query: 919 KPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTIS--TEKPTIPTEKL 976
PT E T T + ST + PT P ++ T PT+S P +
Sbjct: 2304 PPTTELETATTTTTQALFSTPQ---PTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLG 2360
Query: 977 TIPTEKPTIP--TEKPTIPTEKLTALRPPHPSPTATGLAALVMSPH----APSTPMTSVI 1030
T T PT P + +PT+P + L P TG AP+T TS
Sbjct: 2361 TATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRA 2420
Query: 1031 LGTTTTSRSS----TERCPPNARYESCACPASCKSPR--PSCGPLCREGCVCNPGFLFSD 1084
T T S +S T P E A +PR + PL N
Sbjct: 2421 RPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPL------TNTTTSQGT 2474
Query: 1085 NHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCR------CWPGSRVECQ--------IS 1130
C +++ D+ G E+ R CW +EC+ I
Sbjct: 2475 TRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSID 2534
Query: 1131 QCGTHTVCQLKNG 1143
Q G C L+ G
Sbjct: 2535 QVGQVLTCSLETG 2547
Score = 42.0 bits (97), Expect = 0.009
Identities = 48/206 (23%), Positives = 66/206 (32%), Gaps = 9/206 (4%)
Query: 531 PGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEK 590
PGT +P ++ S T LT IST + + P
Sbjct: 2736 PGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTA 2795
Query: 591 PTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTIS 650
+ T T++T PS T P T ++P P T +
Sbjct: 2796 TVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSA 2855
Query: 651 TE--KPTVPTEEPTTPTEET------TTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEE 702
T T EP+T T T TT P + + PS T + S P+ T
Sbjct: 2856 TSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTE-SPPSPGTTTPGHT 2914
Query: 703 TIISTEKPTISPEKPTIPTEKPTIPT 728
T S T +P K T P+ PT
Sbjct: 2915 TATSRTTATATPSKTRTSTLLPSSPT 2940
Score = 33.5 bits (75), Expect = 3.0
Identities = 20/75 (26%), Positives = 37/75 (49%), Gaps = 4/75 (5%)
Query: 654 PTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSI---PTEKPTISMEETIISTEKP 710
P P+ P T + + ++ EP +PT + TEK ++ P+ + T ++ S+ P
Sbjct: 2124 PCGPSPAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGP 2183
Query: 711 -TISPEKPTIPTEKP 724
T++P P T +P
Sbjct: 2184 VTVTPSAPGTTTCQP 2198
Score = 33.5 bits (75), Expect = 3.0
Identities = 30/115 (26%), Positives = 35/115 (30%), Gaps = 18/115 (15%)
Query: 1033 TTTTSRSSTERCPPNARYESCAC-PASCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQAS 1091
T T R+ CP C C +C P C P C G C
Sbjct: 5804 TVTRPRAENPCCPETV----CVCNTTTCPQSLPVCPPGQESICTQEEG------DCCPTF 5853
Query: 1092 SCN---CFYNNDYYEPGAEWFSPNCTEHCRCWPGS----RVECQISQCGTHTVCQ 1139
C C YN +Y GA + C C G V+CQ C T Q
Sbjct: 5854 RCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQ 5908
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 257 bits (657), Expect = 1e-67
Identities = 301/1285 (23%), Positives = 470/1285 (36%), Gaps = 239/1285 (18%)
Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
A C+ GD HY TFDG + F G C YV + C + +D F V RG +
Sbjct: 71 AHNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYED--FNVQL---RRGLVGS 125
Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQ 1655
+ V + L + G V++NG R LP ++ + + S + + + L
Sbjct: 126 RPVVTRVVIKAQGLVLEASNG-SVLINGQREELPY--SRTGLLVEQSGDYIKVSIRLVLT 182
Query: 1656 VRYDGSHLVEVTVPSSYGGQLCGLCGNYNN-NSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714
++G + + Y Q CGLCG++N + ++ + +L +Q G KL
Sbjct: 183 FLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLT--PLQFGNLQKLDGP 240
Query: 1715 SEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG 1774
+E C P + D L+ P F++CH +V + A+C C
Sbjct: 241 TEQ-C----PDPLPLPAGNCTDEEGICHRTLLGPA--FAECHALVDSTAYLAACAQDLCR 293
Query: 1775 TKGDTTALCRSLQAYASLCAQAGQAPA-WRNRTFCPMRCPPGSSYSPCSSPCPDTCSSIN 1833
T C + Y+ CA AG P WR CP CP + C SPC DTCS+
Sbjct: 294 CP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQ 350
Query: 1834 NPRDCPKALPCAESCECQKGHI------LSGTSCVPLGQCGCTDPAGSYHPVGERWYTEN 1887
+ C C + C C G ++ + C+PLGQC CT +Y P + N
Sbjct: 351 RAQLCEDH--CVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSP----GTSFN 404
Query: 1888 TCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGV-GVCQLPGESHYVSFDGSN 1946
T CTCS GL +C+ G C + G +H ++D
Sbjct: 405 TTCSSCTCS---------------------GGLWQCQDLPCPGTCSVQGGAHISTYDEKL 443
Query: 1947 HSIPDACTLVLVKVCHPAMALPFFKISAKHEK-----EEGGTEAFRLHEVYIDIYDAQVT 2001
+ + C+ VL K C + F + A+ K E +A L +D D +
Sbjct: 444 YDLHGDCSYVLSKKCADSS----FTVLAELRKCGLTDNENCLKAVTLS---LDGGDTAIR 496
Query: 2002 LQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEI--EIPT 2059
+Q V +NS LP +S SS + +V +G+Q+ L+++ +
Sbjct: 497 VQADGGVFLNSIYTQLP-LSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDP 555
Query: 2060 TYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPA 2119
+ G++CG+CGNFN + D+ S V + + F N+WK + + ++ D +
Sbjct: 556 AHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLSV 615
Query: 2120 EQQENPSGNC-RAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQ 2178
E + C R D A +++C S I+ PF +C C
Sbjct: 616 ENENYARHWCSRLTDPNSA------------FSRCHSIINPKPFHSNCMFDTCNCERSED 663
Query: 2179 ALCQALQAFGATCQSQGLKPPLWRNSSFCPL--ECPAYSSYTNCLPSCSPSCWDL---DG 2233
LC AL ++ C ++G++ WR+ CP Y + +C P+C L D
Sbjct: 664 CLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADV 723
Query: 2234 RCEGAKVP---------------SAC---------AEGCICQPGYVLSEDKCV------- 2262
C + VP AC A G + PG V+ ++ V
Sbjct: 724 TCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGK 783
Query: 2263 ----------------PRSQCGCKDAHGGSI---------PLGKSWVSSGCTEKCVCTGG 2297
P C ++ G+ L S+ C CVC G
Sbjct: 784 LSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPG 843
Query: 2298 AIQCGDFRCPSGSHCQ-------------LTSDNSNSNCVSDKSE--------QCSVYGD 2336
+ G C + C + D + C + + E C YGD
Sbjct: 844 LVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGD 903
Query: 2337 PRYLTFDGFSYRLQGRMTYVLIKTV--DVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITT 2394
++TFDG Y +G Y+L + D G ++ E N + + +
Sbjct: 904 GHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTE--NIPCGTTGTTCSKAIKLF 961
Query: 2395 VYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI 2454
V Y++ LQ G V P ++ + L ++ + VS+ + + I
Sbjct: 962 VESYELILQEGTFKAVARGPGGDPPYKIRYMGIFL------VIETHGMAVSWDRKTSVFI 1015
Query: 2455 SLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPA 2514
L Y+G V GLCGN+D N ND S ++ + FGNSW++ P A+
Sbjct: 1016 RLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPS-----CPDALAP 1070
Query: 2515 EEEGQGAELGLRTGLQVSECSPEQLASNSTQ-ACRVLADPQGPFAACHQTVAPEPFQEHC 2573
++ C+ + Q C +L P FAAC V + E C
Sbjct: 1071 KD----------------PCTANPFRKSWAQKQCSILHGP--TFAACRSQVDSTKYYEAC 1112
Query: 2574 VLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELY------DTLPSILCQPGRPRG--- 2624
V D C+ + E C + + H + L DT P + C P G
Sbjct: 1113 VNDACACDSGGDCE---CFCTAVAAYAQACHDAGLCVSWRTPDTCP-LFCDFYNPHGGCE 1168
Query: 2625 -------------LRGPLRGRLRQHPRLCLQWHPEPP------------LADCGC-TSNG 2658
R P L P L + PP +A CGC +G
Sbjct: 1169 WHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDKDG 1228
Query: 2659 IYYQLGSSFLTEDCSQRCTCASSRI 2683
YY +G+ T + Q C C S I
Sbjct: 1229 NYYDVGARVPTAENCQSCNCTPSGI 1253
Score = 254 bits (648), Expect = 1e-66
Identities = 211/807 (26%), Positives = 327/807 (40%), Gaps = 88/807 (10%)
Query: 1148 HPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEG 1207
+P C +GD HY TFDG F F G C Y+ ++ C + + F V + G
Sbjct: 69 NPAHNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDF-NVQLRRGLVGSRP 127
Query: 1208 VSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRV 1267
V +++V + + G L+ GQ+ LP G+ + SG ++++ L
Sbjct: 128 V--VTRVVIKAQGLVLEASNGS-VLINGQREELP-YSRTGLLVEQSGDYIKVSIRLVLTF 183
Query: 1268 RWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDED 1327
W+G+ + + Y+ + CGLCG+++G + + + GN + D +
Sbjct: 184 LWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ-FGNLQKLDGPTE 242
Query: 1328 QECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLDMC 1386
Q C + + +C G C R + GP F C V + ++ +C D+C
Sbjct: 243 Q-CPDPLPLPAGNCTDE-------EGICHRTL--LGPAFAECHALVDSTAYLAACAQDLC 292
Query: 1387 GFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSG 1446
C + C AG + WR P CP CP N ++ C PC DTC +
Sbjct: 293 RCPTCP---CATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNP 349
Query: 1447 FSGMFCSDRCVEACECNPGFVLSGLE------CIPRSQCGCLHPAGSYFKVGERWYKPGC 1500
C D CV+ C C PG + L+ C+P QC C H G R Y PG
Sbjct: 350 QRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTH--------GGRTYSPGT 401
Query: 1501 KELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH-AQGAATCTASGDPHYLTFDGALHH 1559
C S C G++ C TC+ G H T+D L+
Sbjct: 402 SFNTTCSS----------------CTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYD 445
Query: 1560 FMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTV--FDLSISLLRGC 1617
G C+YVL++ C DS F V A G + +KAV +++ D +I +
Sbjct: 446 LHGDCSYVLSKKC----ADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADG 501
Query: 1618 KVMLNGHRVALPVWLAQGRVTI-RLSSNLVLLYTNFGLQVRYDGSHLVEVTV--PSSYGG 1674
V LN LP L+ +T+ SS +++ T GLQ+ L++V V ++ G
Sbjct: 502 GVFLNSIYTQLP--LSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQG 559
Query: 1675 QLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLP-------ESSEPGCFLVGGKPS 1727
Q+CGLCGN+N N DD + WK S E C L
Sbjct: 560 QMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSL------ 613
Query: 1728 SCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQ 1787
S + + A W C+ L +P FS+CH ++ P+ ++C+ C + LC +L
Sbjct: 614 SVENENYARHW---CSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALS 670
Query: 1788 AYASLCAQAG-QAPAWRNR--TFCPMRCPPGSSYSPCSSPCPDTCSSINNPR-DCPKALP 1843
+Y CA G Q WR+ T CP Y+ C TC ++ C +
Sbjct: 671 SYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFV 730
Query: 1844 CAESCECQKGHILSGT-SCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNIT 1902
+ C C G L+ +CVP +C C G+ GE + E +C+C+ ++
Sbjct: 731 PVDGCTCPAGTFLNDAGACVPAQECPCY-AHGTVLAPGEVVHDEGA---VCSCT-GGKLS 785
Query: 1903 CFQSTCKPNQICWALDGLLRCRASGVG 1929
C ++ + + C A L C S G
Sbjct: 786 CLGASLQKSTGCAAPMVYLDCSNSSAG 812
Score = 191 bits (485), Expect = 9e-48
Identities = 155/542 (28%), Positives = 223/542 (41%), Gaps = 72/542 (13%)
Query: 1429 NSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLE-CIPRSQCGCLHPAGS 1487
NS C +CH+ G F S CV C C PG V G CI C C+H
Sbjct: 808 NSSAGTPGAECLRSCHTLDVGCF-STHCVSGCVCPPGLVSDGSGGCIAEEDCPCVH---- 862
Query: 1488 YFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEF-CGQQDGIYGCHAQGAATCTASG 1546
E YKPG R+ C CR + + C H TC A G
Sbjct: 863 ----NEATYKPG--------ETIRVDCNTCTCRNRRWECS--------HRLCLGTCVAYG 902
Query: 1547 DPHYLTFDGALHHFMGTCTYVLTRP-CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT 1605
D H++TFDG + F G+C Y+L + C + F + T G + KA+ +
Sbjct: 903 DGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRI-VTENIPCGTTGTTCSKAIKLF 961
Query: 1606 VFDLSISLLRGC-KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLV 1664
V + L G K + G P IR +++ T+ G+ V +D V
Sbjct: 962 VESYELILQEGTFKAVARGPGGDPPY-------KIRYMGIFLVIETH-GMAVSWDRKTSV 1013
Query: 1665 EVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG 1724
+ + Y G++CGLCGN+++N+++D R + GD+++ G +WKL P C
Sbjct: 1014 FIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKL----SPSCPDALA 1069
Query: 1725 KPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG--TKGDTTA 1781
C N +W K C+IL P F+ C V + +CV+ C + GD
Sbjct: 1070 PKDPCTANPFRKSWAQKQCSILHGP--TFAACRSQVDSTKYYEACVNDACACDSGGDCEC 1127
Query: 1782 LCRSLQAYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSPCPDTCSSINN 1834
C ++ AYA C AG +WR CP+ C P G Y PC +PC TC N
Sbjct: 1128 FCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCR--NP 1185
Query: 1835 PRDCPKALPCAESC--ECQKGH-ILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTR 1891
C LP E C +C + + QCGC D G+Y+ VG R T C +
Sbjct: 1186 SGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENC-Q 1244
Query: 1892 LCTCSVHNNITCFQS----TCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNH 1947
C C+ + I C S TC ++ ++ G+G C ++ GSN
Sbjct: 1245 SCNCT-PSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLGAC-------LIAICGSNG 1296
Query: 1948 SI 1949
+I
Sbjct: 1297 TI 1298
Score = 190 bits (482), Expect = 2e-47
Identities = 159/536 (29%), Positives = 221/536 (41%), Gaps = 92/536 (17%)
Query: 1055 CPASCKSPRPSC-GPLCREGCVCNPGFLFSDNH--CIQASSCNCFYNNDYYEPGAEWFSP 1111
C SC + C C GCVC PG L SD CI C C +N Y+PG
Sbjct: 818 CLRSCHTLDVGCFSTHCVSGCVCPPG-LVSDGSGGCIAEEDCPCVHNEATYKPGET---- 872
Query: 1112 NCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRH 1171
RV+C C +N ++ C TC+ YGD H++TFDG
Sbjct: 873 -----------IRVDCN--------TCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDR 913
Query: 1172 FGFMGKCTYILAQP-CG-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR 1229
+ F G C YILAQ CG N+T FR+ +N G G +C + + + + L +G
Sbjct: 914 YSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYELILQEGT 973
Query: 1230 RTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCG 1289
V P P K ++G F+ ++T G+ V WD +++ + Y G++CG
Sbjct: 974 FKAVARGPGGDP--PYKIRYMGI---FLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCG 1027
Query: 1290 LCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSM 1349
LCGN+D N+ ND S GD E GNSW+ C P + + S
Sbjct: 1028 LCGNFDDNAINDFATRSRSVVGDALEFGNSWKL----SPSCPDALAPKDPCTANPFRKSW 1083
Query: 1350 SGPGFCGRLVDTHGP-FETCLLHVKAASFFDSCMLDMCGFQ--GLQHLLCTHMSTMTTTC 1406
+ C L HGP F C V + ++++C+ D C G CT ++ C
Sbjct: 1084 AQKQ-CSIL---HGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQAC 1139
Query: 1407 QDAGHAVKPWREPHFCPMACP---PNS----KYSLCAKPCPDTCHSGFSGMFCSDRCVEA 1459
DAG V WR P CP+ C P+ Y C PC TC + +E
Sbjct: 1140 HDAGLCVS-WRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEG 1198
Query: 1460 C--ECNPG---FVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRC 1514
C +C P F ++C+ +QCGC G+Y+ VG R P + C+S N C
Sbjct: 1199 CYPKCPPSQPFFNEDQMKCV--AQCGCYDKDGNYYDVGAR--VPTAEN---CQSCN---C 1248
Query: 1515 QPWRCRAQEFCGQQDGIYGCHAQGAATCT------ASGDPHYLTFDGALHHFMGTC 1564
P GI H+ A TCT + D Y T DG +G C
Sbjct: 1249 TP------------SGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDG-----LGAC 1287
Score = 169 bits (429), Expect = 3e-41
Identities = 202/884 (22%), Positives = 325/884 (36%), Gaps = 163/884 (18%)
Query: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
VC G+ HY +FDG P C V + C A F + + G R
Sbjct: 76 VCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYE--DFNVQLRR-----GLVGSRPV 128
Query: 1990 EVYIDIYDAQVTLQKGH-RVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFD 2048
+ I + L+ + VLIN ++ LP G+ V+ S Y V+I++ + ++
Sbjct: 129 VTRVVIKAQGLVLEASNGSVLINGQREELPYSRT--GLLVEQSGDYIKVSIRLVLTFLWN 186
Query: 2049 GNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQ 2108
G +E+ Y + CG+CG+FN +P+ + + + + ++ Q
Sbjct: 187 GEDSALLELDPKYANQTCGLCGDFNG-------LPAFNEFYAHNARLTPLQFGNL----Q 235
Query: 2109 SLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN 2168
L +Q P + P+GNC + C L P +A+C + +D T +L CA
Sbjct: 236 KLDGPTEQCP-DPLPLPAGNCTDEE-----GICHRTLLGPAFAECHALVDSTAYLAACAQ 289
Query: 2169 TLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSC 2228
LC C + C G +P WR CP CP + C C+ +C
Sbjct: 290 DLCRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTC 346
Query: 2229 WDLDGR--CEGAKVPSACAEGCICQPGYV------LSEDKCVPRSQCGCKDAHGGSIPLG 2280
+ CE C +GC C PG ++ C+P QC C HGG
Sbjct: 347 SNPQRAQLCE-----DHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPC--THGGRTYSP 399
Query: 2281 KSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYL 2340
+ ++ C+ C C+GG QC D CP CSV G
Sbjct: 400 GTSFNTTCSS-CTCSGGLWQCQDLPCPG---------------------TCSVQGGAHIS 437
Query: 2341 TFDGFSYRLQGRMTYVLIK-----TVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTV 2395
T+D Y L G +YVL K + VL E + L + N L+ V ++
Sbjct: 438 TYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNEN---------CLKAVTLSL 488
Query: 2396 YG--YKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVT-----DFELVVSFGG 2448
G +++QA + +N+ +P +TL+ + + +L+V
Sbjct: 489 DGGDTAIRVQADGGVFLNSIYTQLPL---SAANITLFTPSSFFIVVQTGLGLQLLVQLVP 545
Query: 2449 RKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLR- 2507
+ L ++G + GLCGN+++N+ +D SG + F N+W+ + A R
Sbjct: 546 LMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARN 605
Query: 2508 ---FPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTV 2564
P ++ E E + + C L DP F+ CH +
Sbjct: 606 SFEDPCSLSVENE-----------------------NYARHWCSRLTDPNSAFSRCHSII 642
Query: 2565 APEPFQEHCVLDLCSAQDPREQEELRCQVLSGH----------------GVSSRY----H 2604
P+PF +C+ D C+ + E+ C LS + GV ++Y
Sbjct: 643 NPKPFHSNCMFDTCNCE---RSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCP 699
Query: 2605 ISELYDTLPSILCQPGRPRGLRG----------PLRGRLRQHPRLCLQWHPEPPLADCGC 2654
S+ Y + CQP RGL P+ G P +C C
Sbjct: 700 KSQRYAYVVD-ACQP-TCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPC 757
Query: 2655 TSNGIYYQLGSSFLTEDCSQRCTCASSRI-----LLCEPFSCRAGEVCTLGNHTQGCFPE 2709
++G G + D C+C ++ L + C A V +++ P
Sbjct: 758 YAHGTVLAPGE--VVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPG 815
Query: 2710 SPCLQNPCQNDGQCREQGATFTCECEVGY---GGGLCMEPRDAP 2750
+ CL++ D C C C G G G C+ D P
Sbjct: 816 AECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCP 859
Score = 164 bits (415), Expect = 1e-39
Identities = 261/1104 (23%), Positives = 397/1104 (35%), Gaps = 126/1104 (11%)
Query: 516 SNTASVVAMGFILINPGTCPVKVLPELPPVSPVSSTGPS------ETTGLTENPTISTKK 569
S +S +IL T P +P S+ G + TT T T ST
Sbjct: 4383 STPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTAT 4442
Query: 570 PTVSIEKPSVTTEKPTVPKEKPTIPT-EKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTI 628
P+ + + TE T T+PT T S+ + T + + + PT+ S K T
Sbjct: 4443 PSSTPGTTWILTEPSTTATV--TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT- 4499
Query: 629 LTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEK 688
+ P +P+ + T +T T T P++ T T + + PT S T
Sbjct: 4500 ---PSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTAT-- 4554
Query: 689 PSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTT-----PTE 743
P+ P T++ T T + ++ T T T +T P TT P+
Sbjct: 4555 ---PSSTPETVHTSTVL-TATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSS 4610
Query: 744 KPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTT 803
P P T T PT S +T P+ P + T T++T T
Sbjct: 4611 SPGTALTPPVWISTTTTPTTTTPTTSGSTVT-PSSIPGTTHTARVLTTTTTTVATGSMAT 4669
Query: 804 PTEETTISTEKPSIPMEKPTLPTEETTT---SVEETTISTEKLTIPMEKPTISTEKPTIP 860
P+ T S PS+ T+ +TT S TT T LT P ++ K T
Sbjct: 4670 PSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSS 4729
Query: 861 TEKPTISP-EKLTIPTEKLTIPTEKP----------TIPIEETTISTEKLTIPTEKPTIS 909
+ T + LT K T + P T+P + TT + TI T +
Sbjct: 4730 SSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPET 4789
Query: 910 PEKPTISTEKPTIPTEKPTIPTEETTISTEKL------TIPTEKPTISPEKLTIPTEKPT 963
T+ T T+ + T +T+ T ++ T T T S L+
Sbjct: 4790 THTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTW 4849
Query: 964 ISTEKPTIPTEKLTIPT-------------EKPTIPTEKPTIPTEKLTALRPPHPSPTAT 1010
I TE TI T + +PT P + T T+PT TA P S T
Sbjct: 4850 ILTEPSTIAT--VMVPTGSTATASSTLGTAHTPKVVTTMATMPTA--TASTVPSSSTVGT 4905
Query: 1011 GLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYES-CACPASC---------- 1059
V+ P+ +++V TT R + P++ + + C C A
Sbjct: 4906 TRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGF---PSSHFSTPCFCRAFGQFFSPGEVIY 4962
Query: 1060 -KSPRPSCG--PLCRE---------GCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAE 1107
K+ R C +C + C +P + S + + C +
Sbjct: 4963 NKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGCDNAIPLRQVNET 5022
Query: 1108 WFSPNCTEHCRCWPGSRVE-------CQISQCGTHTVCQLKNGQYGCH-PYAGTATCLVY 1159
W NCT RC +RV ++ H ++ + C Y C ++
Sbjct: 5023 WTLENCTV-ARCVGDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECICSMW 5081
Query: 1160 GDPHYVTFDGRHFGFMGKCTYILAQPC----GNST---DPFFRVTAKNEEQGQEGVSCLS 1212
G HY TFDG + F G CTY+L + GN + D + TA LS
Sbjct: 5082 GGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHY-CTASATAAAARCPRALS 5140
Query: 1213 KVYVTLP-ESTVTLLKGRRT-LVGGQQVTLPAIPSK-GVF---LGASGRFVELQTEFGLR 1266
Y ++ TVT++ G+ L+ Q+ + + SK GV LG + V++ G+
Sbjct: 5141 IHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPA-LGVS 5199
Query: 1267 VRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDE 1326
V ++G S + G CG N +D L+ DG+ A +++ +W
Sbjct: 5200 VTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSR 5259
Query: 1327 DQECQKYQVVNSPSCDSSLQSSMSGPGFC--GRLVD--THGPFETCLLHVKAASFFDSCM 1382
C + ++ SS P C L D F C V FF++C+
Sbjct: 5260 KDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACI 5319
Query: 1383 LDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWR--EPHFCPMACPPNSKYSLCAKPCP 1440
D C +G + C + C+ G WR C + CPP Y C P
Sbjct: 5320 SDHC--RGRLEVPCQSLEAYAELCRARG-VCSDWRGATGGLCDLTCPPTKVYKPCGPIQP 5376
Query: 1441 DTCHSGFSGMFCSDRCVEACECNPGFVLSGLEC-IPRSQCGCLHPAGSYFKVGERWYKPG 1499
TC+S + E C C +L I C C+ P G GERW
Sbjct: 5377 ATCNSRNQSPQL-EGMAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVS-N 5434
Query: 1500 CKELCVC-ESNNRIRCQPWRCRAQ 1522
C+ CVC E + ++C+P C AQ
Sbjct: 5435 CQS-CVCDEGSVSVQCKPLPCDAQ 5457
Score = 153 bits (387), Expect = 2e-36
Identities = 116/493 (23%), Positives = 197/493 (39%), Gaps = 57/493 (11%)
Query: 1044 CPPNARYESCACPAS--CKSPRPS--CGPLCREGCVCNPGFL------FSDNHCIQASSC 1093
CP N +++ C P + C +P+ + C C +GC C PG + + C+ C
Sbjct: 329 CPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQC 388
Query: 1094 NCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGT 1153
C + Y PG F+ C+ C G + C
Sbjct: 389 PCTHGGRTYSPGTS-FNTTCSS----------------------CTCSGGLWQCQDLPCP 425
Query: 1154 ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG-QEGVSCLS 1212
TC V G H T+D + + G C+Y+L++ C +S+ F V A+ + G + +CL
Sbjct: 426 GTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSS---FTVLAELRKCGLTDNENCLK 482
Query: 1213 KVYVTLP--ESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLR--VR 1268
V ++L ++ + + + LP + S F+ +QT GL+ V+
Sbjct: 483 AVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQ 542
Query: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
Q++V + + G++CGLCGN++ N +D L G N+W+
Sbjct: 543 LVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKA----QA 598
Query: 1329 ECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGF 1388
C + C S+++ +C RL D + F C + F +CM D C
Sbjct: 599 ACANARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNC 658
Query: 1389 QGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCP---MACPPNSKYSLCAKPCPDTCHS 1445
+ + LC +S+ C G + WR+ C CP + +Y+ C TC
Sbjct: 659 ERSEDCLCAALSSYVHACAAKGVQLSDWRD-GVCTKYMQNCPKSQRYAYVVDACQPTCRG 717
Query: 1446 -GFSGMFCSDRC--VEACECNPG-FVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCK 1501
+ + CS V+ C C G F+ C+P +C C + G+ GE + G
Sbjct: 718 LSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPC-YAHGTVLAPGEVVHDEGA- 775
Query: 1502 ELCVCESNNRIRC 1514
+C C + ++ C
Sbjct: 776 -VCSC-TGGKLSC 786
Score = 151 bits (382), Expect = 8e-36
Identities = 135/524 (25%), Positives = 205/524 (39%), Gaps = 97/524 (18%)
Query: 1844 CAESCECQKGHILSGTS-CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNIT 1902
C C C G + G+ C+ C C +Y P GE T CTC +
Sbjct: 834 CVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKP-GE---TIRVDCNTCTCR-NRRWE 888
Query: 1903 CFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVK-VC 1961
C C +G C G+ H+++FDG +S +C +L + C
Sbjct: 889 CSHRLC-------------------LGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYC 929
Query: 1962 HPAMALPFFKISAKHEK-EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAI 2020
F+I ++ GT + +++++ Y+ + LQ+G T A+
Sbjct: 930 GDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYE--LILQEG----------TFKAV 977
Query: 2021 SQIPG----VSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEE 2076
++ PG ++ I+ ++ G+ V +D + I + Y G+VCG+CGNF+D
Sbjct: 978 ARGPGGDPPYKIRYMGIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNA 1036
Query: 2077 EDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR 2136
++ S V EF NSWK + PSC L P C A R+
Sbjct: 1037 INDFATRSRSVVGDALEFGNSWK---LSPSCPDALA------------PKDPCTANPFRK 1081
Query: 2137 --AREKCEAALRAPVWAQCASRIDLTPFLVDCAN--TLCEFGGLYQALCQALQAFGATCQ 2192
A+++C + L P +A C S++D T + C N C+ GG + C A+ A+ C
Sbjct: 1082 SWAQKQC-SILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACH 1140
Query: 2193 SQGLKPPLWRNSSFCPLECPAYS-------SYTNCLPSCSPSCWDLDGRCEGAKVPSACA 2245
GL WR CPL C Y+ Y C C +C + G C V
Sbjct: 1141 DAGLCVS-WRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHC---LVDLPGL 1196
Query: 2246 EGCI-----CQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQ 2300
EGC QP + + KCV +QCGC D G +G ++ + C CT IQ
Sbjct: 1197 EGCYPKCPPSQPFFNEDQMKCV--AQCGCYDKDGNYYDVGARVPTAENCQSCNCTPSGIQ 1254
Query: 2301 CGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344
C +S C ++ Y D Y T DG
Sbjct: 1255 CA---------------HSLEACTCTYEDRTYSYQDVIYNTTDG 1283
Score = 139 bits (350), Expect = 4e-32
Identities = 128/480 (26%), Positives = 185/480 (38%), Gaps = 60/480 (12%)
Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIR 1513
DR AC +P V S P GC + A +V E W C + C +NR+
Sbjct: 4983 DRFQGACPTSPPPVSSAPLSSPSPAPGCDN-AIPLRQVNETWTLENCT-VARCVGDNRVV 5040
Query: 1514 CQPWRCRAQEFCGQQ-------DGIYGC--HAQGAATCTASGDPHYLTFDGALHHFMGTC 1564
+ A C + D C H + C+ G HY TFDG + F G C
Sbjct: 5041 LLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECICSMWGGSHYSTFDGTSYTFRGNC 5100
Query: 1565 TYVLTRPCWSR-------SQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGC 1617
TYVL R +R + Y SAT ++H D+ +++
Sbjct: 5101 TYVLMREIHARFGNLSLYLDNHYCTASAT----AAAARCPRALSIHYKSMDIVLTV---- 5152
Query: 1618 KVMLNGHRVALPVWLAQGRVTIRLSSNLVLL-----------YTNFGLQVRYDGSHLVEV 1666
M++G L + Q V+ S N VL+ G+ V ++G
Sbjct: 5153 -TMVHGKEEGL-ILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQAR 5210
Query: 1667 TVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP 1726
S + G CG NN DD L+ D A + W +P+S + GC+ G P
Sbjct: 5211 LPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTP 5270
Query: 1727 SSCQENSMADAW--------NKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGD 1778
+ + + C ++++ F++CH +VPP F +C+ C +G
Sbjct: 5271 PTASPAAPVSSTPTPTPCPPQPLCDLMLSQ--VFAECHNLVPPGPFFNACISDHC--RGR 5326
Query: 1779 TTALCRSLQAYASLCAQAGQAPAWRNRT--FCPMRCPPGSSYSPCSSPCPDTCSSINNPR 1836
C+SL+AYA LC G WR T C + CPP Y PC P TC+S N
Sbjct: 5327 LEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRN--- 5383
Query: 1837 DCPKALPCAESCECQKGHILSGTSC-VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTC 1895
P+ AE C C + IL + + C C P G GERW + + C C
Sbjct: 5384 QSPQLEGMAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSN---CQSCVC 5440
Score = 100 bits (249), Expect = 2e-20
Identities = 151/568 (26%), Positives = 208/568 (36%), Gaps = 51/568 (8%)
Query: 530 NPGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKE 589
N G CP P + SST P T LTE T +T T +T P +
Sbjct: 2970 NYGHCPST--PATSSTATPSST-PGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPK 3026
Query: 590 KPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPS--EKPTILTEKPTIPS----EKPTIP 643
T PT ++ K T S P + P + S K T + P IPS T+P
Sbjct: 3027 VLTSTATTPTATSSKAT-SSSSPRTATTLPVLTSTATKSTATSFTP-IPSFTLGTTGTLP 3084
Query: 644 SEKPTISTEKPTV-PTEEP-TTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISME 701
+ T T+ P+ P TT T T+ T S P+ P ++
Sbjct: 3085 EQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTA 3144
Query: 702 ETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKP-TISPEKPT 760
T + PT +P T T P+ +T++ +T T T T + T
Sbjct: 3145 ATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTAT 3204
Query: 761 TPT-----EKPTISPEKLT-IPTEKPTIPTEKPTIPTEKPTIS-----TEEPTTPTEETT 809
TPT P+ SP T +P + T T T T P+ S T T T T
Sbjct: 3205 TPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTAT 3264
Query: 810 ISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKP--TISTEKPTIPTEKPTIS 867
+ST PS E T+ T T+ TT +T + P P +T+ PT T T +
Sbjct: 3265 MSTATPSSTPE--TVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTAT 3322
Query: 868 PEKLTIPTEKLTIPTEKPTIPIEETTISTEK--LTIPTEKPTISPEKPTISTEKPTIPTE 925
P + P LT P + I TT T + P+ P + ++T T+ T
Sbjct: 3323 PS--SSPGTALT-----PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATG 3375
Query: 926 KPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTI 985
P+ T S ++ T TI+ T +T P + T T P
Sbjct: 3376 SMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPA----- 3430
Query: 986 PTEKPTIPTEKL-TALRPPHPSPTAT--GLAALVMSPHAPSTPMTSV---ILGTT--TTS 1037
T P+ L T PP P+ TAT G + SPH T TS ILGTT T
Sbjct: 3431 ATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEP 3490
Query: 1038 RSSTERCPPNARYESCACPASCKSPRPS 1065
+ T P + + SP PS
Sbjct: 3491 STVTSHTPAATTSTTQHSTPALSSPHPS 3518
Score = 99.4 bits (246), Expect = 5e-20
Identities = 152/613 (24%), Positives = 222/613 (36%), Gaps = 62/613 (10%)
Query: 468 LLGSPAGSPPIPLWKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFI 527
+L SPA +P K S P T+ T+P L + + T+
Sbjct: 4284 VLTSPATTPTATSSKATSSSSP---RTATTLPV-------LTSTATKSTATSVTPIPSST 4333
Query: 528 LINPGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVP 587
L GT P + PV+ +S+ PS T T T+ T K T + + + +T P+
Sbjct: 4334 LGTTGTLPEQTTT---PVATMSTIHPSSTPETTHTSTVLTTKATTT--RATSSTSTPSST 4388
Query: 588 KEKPTIPTEKPT-ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTE-----KPTIPSEKP- 640
I TE T +T T P+ P+ I +E T T PS P
Sbjct: 4389 PGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPG 4448
Query: 641 -----TIPSEKPTIST---EKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIP 692
T PS T++ T + + T T +T+ P + + K + P+ P
Sbjct: 4449 TTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSK-ATPSSSPGTA 4507
Query: 693 TEKPTISMEETIISTEKPTISPEKPTIPT----EKPTIPT-EKSTISPEKPTTPTEKPTI 747
T P + T + T P T + T PT ST +P T+
Sbjct: 4508 TALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTV 4567
Query: 748 PTEKPTISPEKPTTPTEKPTISPEKLT-IPTEKPT----IPTEKPTIPTEKPT--ISTEE 800
T T + + T T T +PT T P+ P P +T
Sbjct: 4568 LTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTT 4627
Query: 801 PTTPTEETTISTEKP-SIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTI 859
PTT T T+ ST P SIP T TTT TT++T + P S P++
Sbjct: 4628 PTTTTPTTSGSTVTPSSIPGTTHTARVLTTTT----TTVATGSMATPSSSTQTSGTPPSL 4683
Query: 860 PTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPT---IS 916
T TI+ T T + P P P+ +T +T T + SP T +
Sbjct: 4684 TTTATTITATGST--TNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVL 4741
Query: 917 TEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKL 976
T T T P +T+ T T+P + T TI T +T T+ T
Sbjct: 4742 TSTATKSTATSFTPIPSSTLWT-TWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTA 4800
Query: 977 TIPTEKPTIPTEKPTIPTEK-LTALRPPHPSPTATGLAALVMSPHA-------PSTPMTS 1028
T+ + T T+ T + LT L + ATG A + S PST T
Sbjct: 4801 TMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATV 4860
Query: 1029 VILGTTTTSRSST 1041
++ +T + SST
Sbjct: 4861 MVPTGSTATASST 4873
Score = 95.1 bits (235), Expect = 9e-19
Identities = 149/593 (25%), Positives = 225/593 (37%), Gaps = 79/593 (13%)
Query: 468 LLGSPAGSPPIPLWKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFI 527
+L S A +P K S P T+ T+P L + + T+ F
Sbjct: 3027 VLTSTATTPTATSSKATSSSSP---RTATTLPV-------LTSTATKSTATSFTPIPSFT 3076
Query: 528 LINPGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVP 587
L GT P + P++ +S+ PS T T T+ T K T + S++T P+
Sbjct: 3077 LGTTGTLPEQTTT---PMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMST--PSST 3131
Query: 588 KEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPS-EK 646
I TE T +T + P+ P+ ILTE T + T+P+
Sbjct: 3132 PGTTWILTELTTAAT------TTAATGPTATPSSTPGTTWILTEPSTTATV--TVPTGST 3183
Query: 647 PTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEK--PTISMEETI 704
T S+ + T T + T T T T + P+ P T P++ + PT + I
Sbjct: 3184 ATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAI 3243
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTE 764
S+ T T T+ T + +PE T T T T T + TP+
Sbjct: 3244 PSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTT--TRATGSVATPSS 3301
Query: 765 KPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEP----TTPTEETTISTEKPS-IPM 819
P + +PT T T P+ P + P TT T T ST PS IP
Sbjct: 3302 TPGTA-HTTKVPT---TTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPG 3357
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEK-------PTISTEKPTIPTEKPTISPEKLT 872
T TTT TT++T + P P+++T TI T +P
Sbjct: 3358 TTHTATVLTTTT----TTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPS--- 3410
Query: 873 IPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKP------TISPEKP--TISTEKPTIPT 924
+ P P P+ TT +T T T P T +P P T +T ++P
Sbjct: 3411 ------STPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPP 3464
Query: 925 EKP-TIPTEETT-----ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTI 978
P T+ T T+ + T +T P+ + +P T T+ T + P P+ + T
Sbjct: 3465 SSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPH-PSSRTTE 3523
Query: 979 PTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAP-STPMTSVI 1030
P T T T + TA P + T+T + P +P S P+T+V+
Sbjct: 3524 SPPSPGTTTPGHTRGTSRTTATATPSKTRTST------LLPSSPTSAPITTVV 3570
Score = 94.4 bits (233), Expect = 1e-18
Identities = 153/568 (26%), Positives = 209/568 (36%), Gaps = 73/568 (12%)
Query: 530 NPGTCPVKVLPELPPVSPVSSTGPSETTGLTE-NPTISTKKPTVSIEKPSVTTEKPTVPK 588
N G CP P + SST P T LTE T +T T S PS T PK
Sbjct: 4227 NYGHCPST--PATSSTAMPSST-PGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPK 4283
Query: 589 EKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPS--EKPTILTEKPTIPSE----KPTI 642
T P PT ++ K T S P + P + S K T + P IPS T+
Sbjct: 4284 VL-TSPATTPTATSSKAT-SSSSPRTATTLPVLTSTATKSTATSVTP-IPSSTLGTTGTL 4340
Query: 643 PSEKPT-ISTEKPTVPTEEP-TTPTEETTTSMEEPVIPTEKPSIPTEKPS---IPTEKPT 697
P + T ++T P+ P TT T T+ T S P+ P I TE T
Sbjct: 4341 PEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTT 4400
Query: 698 ISMEETIIS-TEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKP----------- 745
+ T P+ +P I TE T T +T S TP+ P
Sbjct: 4401 AATTTAATGPTATPSSTPGTTWILTELTT--TATTTASTGSTATPSSTPGTTWILTEPST 4458
Query: 746 ----TIPT--------EKPTISPEKPTTPTEKPTISPEKLTIPTEKP----TIPTEKPTI 789
T+PT + T +T PT++ K T P+ P +P + T
Sbjct: 4459 TATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT-PSSSPGTATALPALRSTA 4517
Query: 790 PTEKPTISTEEPT------------TPTEETTISTEKPSIPMEKPTLPTEETTTSVEETT 837
T T T P+ T T T+ST PS E T+ T T+ TT
Sbjct: 4518 TTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE--TVHTSTVLTATATTT 4575
Query: 838 ISTEKLTIPMEKP--TISTEKPTIPTEKPTISPEKLTIPTEKLTIPT--EKPTIPIEETT 893
+T + P P +T+ PT T T +P + P LT P T P T
Sbjct: 4576 GATGSVATPSSTPGTAHTTKVPTTTTTGFTATPS--SSPGTALTPPVWISTTTTPTTTTP 4633
Query: 894 ISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPE 953
++ P+ P + ++T T+ T P+ T S ++ T TI+
Sbjct: 4634 TTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTIT-- 4691
Query: 954 KLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA 1013
T T P+ ST T T LT P + K T + TA P + TAT
Sbjct: 4692 -ATGSTTNPS-STPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKST 4749
Query: 1014 ALVMSPHAPSTPMTSVILGTTTTSRSST 1041
A +P ST T+ + TT+ ST
Sbjct: 4750 ATSFTPIPSSTLWTTWTVPAQTTTPMST 4777
Score = 93.2 bits (230), Expect = 3e-18
Identities = 121/519 (23%), Positives = 191/519 (36%), Gaps = 77/519 (14%)
Query: 1825 CPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWY 1884
C C CP + P S LS S P GC D A V E W
Sbjct: 4976 CNQHCDIDRFQGACPTSPPPVSSAP------LSSPSPAP----GC-DNAIPLRQVNETWT 5024
Query: 1885 TENTCTRLCTCSVHN-----------NITCFQS-----TCKPNQICWALDGLLRCRASGV 1928
EN CT + C N N+TC P+Q C D C
Sbjct: 5025 LEN-CT-VARCVGDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPC---DFHYECEC--- 5076
Query: 1929 GVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPA---MALPFFKISAKHEKEEGGTEA 1985
+C + G SHY +FDG++++ CT VL++ H ++L
Sbjct: 5077 -ICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAARC 5135
Query: 1986 FRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPG----------VSVKSSSIYS 2035
R ++ D +T+ +++ K+ L QIP VSV ++
Sbjct: 5136 PRALSIHYKSMDIVLTV-----TMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMR 5190
Query: 2036 IVNIKIGVQVKFDGNHLLEIEIP-TTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEF 2094
+ +GV V F+G + + +P + ++ G CG + + D+ + A S +
Sbjct: 5191 VDIPALGVSVTFNG-QVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDM 5249
Query: 2095 VNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCA 2154
+W D P P + + C+ L + V+A+C
Sbjct: 5250 AKTWLVP--DSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLML-SQVFAECH 5306
Query: 2155 SRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSS--FCPLECP 2212
+ + PF C + C G + CQ+L+A+ C+++G+ WR ++ C L CP
Sbjct: 5307 NLVPPGPFFNACISDHCR--GRLEVPCQSLEAYAELCRARGVCSD-WRGATGGLCDLTCP 5363
Query: 2213 AYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDK---CVPRSQCGC 2269
Y C P +C + R + ++ AEGC C +L CV C C
Sbjct: 5364 PTKVYKPCGPIQPATC---NSRNQSPQL-EGMAEGCFCPEDQILFNAHMGICV--QACPC 5417
Query: 2270 KDAHGGSIPLGKSWVSSGCTEKCVCTGG--AIQCGDFRC 2306
G G+ WVS+ + CVC G ++QC C
Sbjct: 5418 VGPDGFPKFPGERWVSN--CQSCVCDEGSVSVQCKPLPC 5454
Score = 86.3 bits (212), Expect = 4e-16
Identities = 129/494 (26%), Positives = 195/494 (39%), Gaps = 89/494 (18%)
Query: 554 SETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPT-EKPTISTEKPTIPSEKP 612
+E+TG T P+ ST T + +PS T TV T+PT T S+ + T +
Sbjct: 3706 TESTGSTATPS-STPGTTWILTEPSTTA---TV-----TVPTGSTATASSTQATAGTPHV 3756
Query: 613 NMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSM 672
+ + PT+ S K T + P +P+ + T +T T T P++ T T +
Sbjct: 3757 STTATTPTVTSSKATPFSS----PGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRL 3812
Query: 673 EEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKST 732
+ PT S T P+ P + T+++T T +T
Sbjct: 3813 SQTTTPTATMSTAT-----PSSTPETAHTSTVLTT--------------------TATTT 3847
Query: 733 ISPEKPTTPTEKP-TIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPT 791
+ TP+ P T T K PTT T T++P + T T
Sbjct: 3848 RATGSVATPSSTPGTAHTTKV------PTTTTTGFTVTPS------------SSPGTART 3889
Query: 792 EKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPT 851
IST TTPT T+ ST PS PT TTT+ TT++T + P
Sbjct: 3890 PPVWIST--TTTPT--TSGSTVTPSSVPGTTHTPTVLTTTT---TTVATGSMATPSSSTQ 3942
Query: 852 ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKP----- 906
S P++ T TI+ T T + P P P+ TT +T T T P
Sbjct: 3943 TSGTPPSLITTATTITATGST--TNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALG 4000
Query: 907 -TISPEKP--TISTEKPTI-PTEKPTIPTEET-----TISTEKLTIPTEKPTISPEKLTI 957
T +P P T +T ++ P+ T+ T T T+ T +T P+ + +P T
Sbjct: 4001 TTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTG 4060
Query: 958 PTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVM 1017
T+ T + P P+ + T P T T T + TA P + T+T +
Sbjct: 4061 TTQHSTPALSSPH-PSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTST------L 4113
Query: 1018 SPHAP-STPMTSVI 1030
P +P S P+T+V+
Sbjct: 4114 LPSSPTSAPITTVV 4127
Score = 82.4 bits (202), Expect = 6e-15
Identities = 143/519 (27%), Positives = 201/519 (38%), Gaps = 79/519 (15%)
Query: 530 NPGTCPVKVLPELPPVSPVSSTGPSETTGLTE-NPTISTKKPTVSIEKPSVTTEKPTVPK 588
N G CP P + SST P T LTE T +T + T S PS T +
Sbjct: 2413 NYGHCPST--PATSSTAMPSST-PGTTWILTELTTTATTTESTGSTATPSSTPGTTWILT 2469
Query: 589 EKPTIPTEK-PTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
E T T PT ST + P T + PT+ S K T P P
Sbjct: 2470 EPSTTATVTVPTGSTATASSTQATAGTPHVSTTATT---------PTVTSSKAT-PFSSP 2519
Query: 648 TISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIST 707
+T P + + TTPT + T++ + T + T PT +M ST
Sbjct: 2520 GTATALPALRSTA-TTPTATSFTAIPSSSLGTTWTRLSQ------TTTPTATM-----ST 2567
Query: 708 EKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKP-TIPTEKPTISPEKPTTPTEKP 766
P+ +PE T+ T T +T + TP+ P T T K TT T
Sbjct: 2568 ATPSSTPE--TVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVL------TTTTTGF 2619
Query: 767 TISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPT 826
T +P + P T+P IST TTPT T ST PS PT
Sbjct: 2620 TATPS---------SSPGTARTLPV---WISTT--TTPT--TRGSTVTPSSIPGTTHTPT 2663
Query: 827 EETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPT 886
TTT+ TT++T + P S P++ T TI+ T T + P P
Sbjct: 2664 VLTTTT---TTVATGSMATPSSSTQTSGTPPSLTTTATTITATGST--TNPSSTPGTTPI 2718
Query: 887 IPIEETTISTEKLTIPTEKP------TISPEKP--TISTEKPTI-PTEKPTIPTEET--- 934
P+ TT +T T T P T +P P T +T ++ P+ T+ T T
Sbjct: 2719 PPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSAT 2778
Query: 935 --TISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTI 992
T+ T +T P+ + +P T T+ T + P P+ + T P T T
Sbjct: 2779 SGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPH-PSSRTTESPPSPGTTTPGHTR 2837
Query: 993 PTEKLTALRPPHPSPTATGLAALVMSPHAP-STPMTSVI 1030
T + TA P + T+T + P +P S P+T+V+
Sbjct: 2838 ATSRTTATATPSKTRTST------LLPSSPTSAPITTVV 2870
Score = 80.1 bits (196), Expect = 3e-14
Identities = 112/471 (23%), Positives = 172/471 (36%), Gaps = 62/471 (13%)
Query: 571 TVSIEKPSVTTEKPTV-PKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTIL 629
T S PS T + K T T T ST PT + + P + T + PT+
Sbjct: 1894 TSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPT-STLRTAPPPKVLTTTATTPTVT 1952
Query: 630 TEKPTIPSEKP----TIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685
+ K T PS P +P+ + T +T T T P++ T T + + PT S
Sbjct: 1953 SSKAT-PSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTA 2011
Query: 686 TEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTT----- 740
T P+ P + T++ T T + ++ T T T +T P TT
Sbjct: 2012 T-----PSSTPETAHTSTVL-TATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTAT 2065
Query: 741 PTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEE 800
P+ P P T T T++P + T T+ T T T++T
Sbjct: 2066 PSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTT------TVATGS 2119
Query: 801 PTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIP 860
TP+ T S PS+ T+ +TT+ T +T IP P ++T T
Sbjct: 2120 MATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTT---PIP---PVLTTTATTPA 2173
Query: 861 TEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKP 920
T++P T T P+ T +T ++P SP +
Sbjct: 2174 ATSNTVTPSSALGTTH---------TPPVPNTMATTHGRSLPPS----SPHTVRTAWTSA 2220
Query: 921 TIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPT 980
T T TE +T+++ L T S L+ P P+ + T
Sbjct: 2221 TSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPH------------PSSRTTESP 2268
Query: 981 EKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAP-STPMTSVI 1030
P T T T + TA P + T+T + P +P S P+T+V+
Sbjct: 2269 PSPGTTTPGHTTATSRTTATATPSKTRTST------LLPSSPTSAPITTVV 2313
Score = 80.1 bits (196), Expect = 3e-14
Identities = 118/468 (25%), Positives = 174/468 (37%), Gaps = 87/468 (18%)
Query: 661 PTTPTEETTTSMEEPVIPTEKPS---IPTEKPSIPTEKPTISMEETIISTEKPTISPEKP 717
P+TP +T +P+ P I TE + T + T ST P+
Sbjct: 4232 PSTPATSSTA------MPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVL 4285
Query: 718 TIPTEKPTIPTEKSTISPEKPTTPTEKPTI-------------PTEKPTIS-----PEKP 759
T P PT + K+T S P T T P + P T+ PE+
Sbjct: 4286 TSPATTPTATSSKAT-SSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQT 4344
Query: 760 TTP-TEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTE-KPSI 817
TTP TI P T T+ T K T T + T ST P++ T I TE +
Sbjct: 4345 TTPVATMSTIHPSSTPETTHTSTVLTTKAT--TTRATSSTSTPSSTPGTTWILTELTTAA 4402
Query: 818 PMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTE- 876
T PT +++ T I TE T T +T T T P+ +P I TE
Sbjct: 4403 TTTAATGPTATPSSTPGTTWILTELTT------TATTTASTGSTATPSSTPGTTWILTEP 4456
Query: 877 ----KLTIPT-EKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPT---IPTEKPT 928
+T+PT T + T T ++ PT++ K T S+ T +P + T
Sbjct: 4457 STTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRST 4516
Query: 929 IPTEETT-------------------ISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKP 969
T T +T T+ T P+ +PE T+ T +T
Sbjct: 4517 ATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE--TVHTSTVLTATATT 4574
Query: 970 TIPTEKLTIPTEKP--TIPTEKPTIPTEKL---------TALRPP-------HPSPTATG 1011
T T + P+ P T+ PT T TAL PP P+ T
Sbjct: 4575 TGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPT 4634
Query: 1012 LAALVMSPHA-PSTPMTSVILGTTTTSRSSTERCPPNARYESCACPAS 1058
+ ++P + P T T+ +L TTTT+ ++ P++ ++ P S
Sbjct: 4635 TSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPS 4682
Score = 78.6 bits (192), Expect = 8e-14
Identities = 120/478 (25%), Positives = 177/478 (37%), Gaps = 60/478 (12%)
Query: 612 PNMPSEKPTI-PSEKPT---ILTEKPTIPSEKPT-----IPSEKPTISTEKPTVPTEEPT 662
P+ P+ T PS P ILTE+ T + T IPS P + P V T T
Sbjct: 2975 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPG-TAPPPKVLTSTAT 3033
Query: 663 TPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTIS-PEKPTIPT 721
TPT ++ + S P ++P T + T P+ + T+P
Sbjct: 3034 TPTATSSKATSS--------SSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPE 3085
Query: 722 EKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPT 781
+ T STI P T T+ T K T + + T+ P+ +P I TE T
Sbjct: 3086 QTTTPMATMSTIHPSSTPETTHTSTVLTTKATTT--RATSSMSTPSSTPGTTWILTELTT 3143
Query: 782 IPTEKP-TIPTEKPTIST------EEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVE 834
T T PT P+ + EP+T T + + + T T + TS
Sbjct: 3144 AATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTA 3203
Query: 835 ETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLT-IPTEKLTIPTEKPTIPIEETT 893
T P P +T P + + T + +T IP+ L + + +TT
Sbjct: 3204 TTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTR----LSQTT 3259
Query: 894 ISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPE 953
T T+ T P+ +PE T+ T T TT +T + P+ P +
Sbjct: 3260 TPTA--TMSTATPSSTPE---------TVHTSTVLTTTTTTTRATGSVATPSSTPG-TAH 3307
Query: 954 KLTIPTEKPTISTEKP-TIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGL 1012
+PT T T P + P LT P T T PT +T P + TAT L
Sbjct: 3308 TTKVPTTTTTGFTATPSSSPGTALTPPVWIST--TTTPTTRGSTVTPSSIPGTTHTATVL 3365
Query: 1013 AALVMSPHAPSTPMTSVILGTTTTSRSSTER--CPPNARYESCACPASCKSPRPSCGP 1068
+T T+V G+ T SST+ PP+ + A+ + PS P
Sbjct: 3366 ----------TTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTP 3413
Score = 78.2 bits (191), Expect = 1e-13
Identities = 102/368 (27%), Positives = 141/368 (38%), Gaps = 36/368 (9%)
Query: 689 PSIPTEKPTISMEET-----IISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTE 743
PS P T + T I++ T + T T PT T ++ P+ TT
Sbjct: 1889 PSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPT-STLRTAPPPKVLTTTAT 1947
Query: 744 KPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTT 803
PT+ + K T S P T T P + T PT P ++ T +S + TT
Sbjct: 1948 TPTVTSSKATPS-SSPGTATALPALR-STATTPTATSVTPIPSSSLGTTWTRLS--QTTT 2003
Query: 804 PTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKP--TISTEKPTIPT 861
PT T+ST PS E T T T+ TT +T + P P +T+ PT T
Sbjct: 2004 PT--ATMSTATPSSTPE--TAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTT 2059
Query: 862 EKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEK--LTIPTEKPTISPEKPTISTEK 919
T +P + P LT P + I TT T + P+ P + ++T
Sbjct: 2060 TGFTATPS--SSPGTALT-----PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTT 2112
Query: 920 PTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIP 979
T+ T P+ T S ++ T TI+ T +T P + T T P
Sbjct: 2113 TTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTP 2172
Query: 980 TEKPTIPTEKPTIPTEKL-TALRPPHPSPTAT--GLAALVMSPHAPSTPMTSV---ILGT 1033
T P+ L T PP P+ AT G + SPH T TS ILGT
Sbjct: 2173 A-----ATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGT 2227
Query: 1034 TTTSRSST 1041
T + ST
Sbjct: 2228 THITEPST 2235
Score = 78.2 bits (191), Expect = 1e-13
Identities = 115/430 (26%), Positives = 161/430 (37%), Gaps = 54/430 (12%)
Query: 661 PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP 720
P+TP +T + P+ P + T T + E+ ST P+ +P I
Sbjct: 3675 PSTPATSSTAT------PSSTPGTTWILTKLTT---TATTTESTGSTATPSSTPGTTWIL 3725
Query: 721 TEKPT-----IPT-EKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLT 774
TE T +PT +T S + T T + PT++ K T P SP T
Sbjct: 3726 TEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT-----PFSSPGTAT 3780
Query: 775 -IPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSV 833
+P + T T T T P+ S T +TT T S T T T+T V
Sbjct: 3781 ALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTST-V 3839
Query: 834 EETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETT 893
TT +T + T + P+ ST T+ PT + T+ P + I TT
Sbjct: 3840 LTTTATTTRATGSVATPS-STPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTT 3898
Query: 894 ISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPE 953
T T T++P +T PT+ T T TT++T + P+ S
Sbjct: 3899 TPT------TSGSTVTPSSVPGTTHTPTVLT------TTTTTVATGSMATPSSSTQTSGT 3946
Query: 954 KLTIPTEKPTI----STEKPTIPTEKLTIP---TEKPTIP--TEKPTIPTEKL-TALRPP 1003
++ T TI ST P+ IP T T P T P+ L T PP
Sbjct: 3947 PPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPP 4006
Query: 1004 HPSPTATGLAALVMSPHAPS------TPMTSVILGTT--TTSRSSTERCPPNARYESCAC 1055
P+ TAT +SP +P T TS LGTT T + T P +
Sbjct: 4007 VPNTTAT-THGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHS 4065
Query: 1056 PASCKSPRPS 1065
+ SP PS
Sbjct: 4066 TPALSSPHPS 4075
Score = 73.9 bits (180), Expect = 2e-12
Identities = 115/437 (26%), Positives = 163/437 (37%), Gaps = 68/437 (15%)
Query: 661 PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP 720
P+TP +T +P+ P + T T + E+ ST P+ +P I
Sbjct: 2418 PSTPATSSTA------MPSSTPGTTWILTELTT---TATTTESTGSTATPSSTPGTTWIL 2468
Query: 721 TEKPT-----IPT-EKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLT 774
TE T +PT +T S + T T + PT++ K T P SP T
Sbjct: 2469 TEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT-----PFSSPGTAT 2523
Query: 775 -IPTEKPTIPTEKPTIPTEKPTIST-------EEPTTPTEETTISTEKPSIPMEKPTLPT 826
+P + T T T T P+ S + TTPT T+ST PS E T+ T
Sbjct: 2524 ALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPT--ATMSTATPSSTPE--TVHT 2579
Query: 827 EETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPT 886
T+ TT +T + P P + + T + + P T+P
Sbjct: 2580 STVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLP----- 2634
Query: 887 IPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTE 946
+ I TT T T T++P +T PT+ T T TT++T + P+
Sbjct: 2635 VWISTTTTPT------TRGSTVTPSSIPGTTHTPTVLT------TTTTTVATGSMATPSS 2682
Query: 947 KPTISPEKLTIPTEKPTI----STEKPTIPTEKLTIP---TEKPTIP--TEKPTIPTEKL 997
S ++ T TI ST P+ IP T T P T P+ L
Sbjct: 2683 STQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSAL 2742
Query: 998 -TALRPPHPSPTATGLAALVMSPHAPS------TPMTSVILGTT--TTSRSSTERCPPNA 1048
T PP P+ TAT +SP +P T TS LGTT T + T P
Sbjct: 2743 GTTHTPPVPNTTAT-THGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAAT 2801
Query: 1049 RYESCACPASCKSPRPS 1065
+ + SP PS
Sbjct: 2802 TGTTQHSTPALSSPHPS 2818
Score = 73.9 bits (180), Expect = 2e-12
Identities = 133/547 (24%), Positives = 200/547 (36%), Gaps = 48/547 (8%)
Query: 531 PGTCPVKVLPELPP----VSPVSSTGPSET--TGLTENPTISTKKPTVSIEKPSVTTEKP 584
PGT +P V+P SS G + T ++ T +T TV+ TT P
Sbjct: 3860 PGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTP 3919
Query: 585 TVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTIL-TEKPTIPSEKP-TI 642
TV + T T++T PS P++ + TI T T PS P T
Sbjct: 3920 TV------LTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTT 3973
Query: 643 PSEKPTISTEKPTVP--TEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISM 700
P P + T T P T TP+ T+ PV T + T S+ P ++
Sbjct: 3974 PI--PPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNT---TATTHGRSLSPSSPH-TV 4027
Query: 701 EETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKP- 759
S T+ T P+ T T +T + +TP P+ + T SP P
Sbjct: 4028 RTAWTSATSGTLGTTHITEPS-TGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPG 4086
Query: 760 -TTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTE--KPS 816
TTP S T K T P+ PT P T TT E +E S
Sbjct: 4087 TTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPI--TTVVTTGCEPQCAWSEWLDYS 4144
Query: 817 IPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPT----EKPTISPEKLT 872
PM P+ +T +++ + + + +E + +P +P + S +
Sbjct: 4145 YPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLE--CRAQAQPGVPLGELGQVVECSLDFGL 4202
Query: 873 IPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTE 932
+ + + K E P+ T S P+ + I TE T T
Sbjct: 4203 VCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTT--TA 4260
Query: 933 ETTISTEKLTIPTEKPTIS--PEKLTIPTEKPTISTEKPT---IPTEKLTIP----TEKP 983
TT ST P+ P + P+ LT P PT ++ K T P T+P T
Sbjct: 4261 TTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATK 4320
Query: 984 TIPTEKPTIPTEKL-TALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGT-TTTSRSST 1041
+ T IP+ L T P + T + + P T TS +L T TT+R+++
Sbjct: 4321 STATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATS 4380
Query: 1042 ERCPPNA 1048
P++
Sbjct: 4381 STSTPSS 4387
Score = 72.4 bits (176), Expect = 6e-12
Identities = 119/490 (24%), Positives = 175/490 (35%), Gaps = 53/490 (10%)
Query: 580 TTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEK 639
TT PT E T T + ST +PT P + P + PT L+E T P
Sbjct: 1611 TTPPPTTELETATTTTTQALFSTPQPT---SSPGLTRAPPASTTAVPT-LSEGLTSPRYT 1666
Query: 640 PTIPSEKPTISTEKPTVP--TEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPT 697
T+ T +T PT P + EPT P T+T +P S+ T +PS P PT
Sbjct: 1667 STL----GTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQP---PT 1719
Query: 698 ISMEETIISTEKPT----ISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPT 753
++ S +PT + ++P + PT+ +E ST E T TE T
Sbjct: 1720 LAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTE--------TT 1771
Query: 754 ISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPT---------TP 804
+SP TT ++ T K TE + PT + T E P
Sbjct: 1772 MSPLTNTTTSQGTTRCQPKCEW-TE--WFDVDFPTSGVAGGDMETFENIRAAGGKMCWAP 1828
Query: 805 TEETTISTEKPSIPMEKP----TLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIP 860
+ P + +++ T E T E + + + +
Sbjct: 1829 KSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHC 1888
Query: 861 TEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKP 920
P S T T KPT TT ST PT +P ++T
Sbjct: 1889 PSTPATSSTATPSSTPGTTWILTKPT-TTATTTASTGSTATPTSTLRTAPPPKVLTTTAT 1947
Query: 921 TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLT 977
T PT+ + + T S+ T +P + T + T T P+ S + T
Sbjct: 1948 T-----PTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTT 2002
Query: 978 IPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHA-PSTPMTSVILGTTTT 1036
PT T+ T P+ E + T TG V +P + P T T+ + TTTT
Sbjct: 2003 TPT--ATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTT 2060
Query: 1037 SRSSTERCPP 1046
++T P
Sbjct: 2061 GFTATPSSSP 2070
Score = 65.5 bits (158), Expect = 7e-10
Identities = 122/546 (22%), Positives = 187/546 (34%), Gaps = 39/546 (7%)
Query: 531 PGTCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEK 590
PGT +P ++ S T LT IST + + P
Sbjct: 2046 PGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTA 2105
Query: 591 PTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTIL-TEKPTIPSEKP-TIPSEKPT 648
+ T T++T PS P++ + TI T T PS P T P P
Sbjct: 2106 TVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPI--PP 2163
Query: 649 ISTEKPTVP--TEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIS 706
+ T T P T TP+ T+ PV T T S+P P ++ S
Sbjct: 2164 VLTTTATTPAATSNTVTPSSALGTTHTPPVPNT---MATTHGRSLPPSSPH-TVRTAWTS 2219
Query: 707 TEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKP--TTPTE 764
+ T P+ T T +T + +TP P+ + T SP P TTP
Sbjct: 2220 ATSGILGTTHITEPS-TVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGH 2278
Query: 765 KPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTL 824
S T K T P+ PT P + + S PM P+
Sbjct: 2279 TTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSG 2338
Query: 825 PTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEK-----------PTISPEKLTI 873
+T +++ + + + +E + +P +P + + + +
Sbjct: 2339 GDFDTYSNIRAAGGAVCEQPLGLE--CRAQAQPGVPLRELGQVVECSLDFGLVCRNREQV 2396
Query: 874 PTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEE 933
K+ E + T T P+ +P I TE T T + +
Sbjct: 2397 GKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTA 2456
Query: 934 TTISTEKLT-IPTEKPTISPEKLTIPT-EKPTISTEKPTIPTEKLTIPTEKPTIPTEKPT 991
T ST T I TE T + +T+PT T S+ + T T ++ PT+ + K T
Sbjct: 2457 TPSSTPGTTWILTEPSTTA--TVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT 2514
Query: 992 I-----PTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPP 1046
L ALR +PTAT A+ S S T L TTT ++ P
Sbjct: 2515 PFSSPGTATALPALRSTATTPTATSFTAIPSS----SLGTTWTRLSQTTTPTATMSTATP 2570
Query: 1047 NARYES 1052
++ E+
Sbjct: 2571 SSTPET 2576
Score = 60.1 bits (144), Expect = 3e-08
Identities = 80/322 (24%), Positives = 124/322 (38%), Gaps = 35/322 (10%)
Query: 756 PEKP-TTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEK 814
P P T+ T P+ +P I TE T T T + T ST P++ T I TE
Sbjct: 2418 PSTPATSSTAMPSSTPGTTWILTELTTTAT------TTESTGSTATPSSTPGTTWILTEP 2471
Query: 815 PSIPMEKPTLPTEETTT-SVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLT- 872
+ T+PT T T S + T T ++ PT+++ K T P SP T
Sbjct: 2472 STTATV--TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT-----PFSSPGTATA 2524
Query: 873 IPTEKLTIPTEKPT----IPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPT 928
+P + T T T IP + +L+ T PT + T S+ T+ T
Sbjct: 2525 LPALRSTATTPTATSFTAIPSSSLGTTWTRLS-QTTTPTATMSTATPSSTPETVHTSTVL 2583
Query: 929 IPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTE 988
T TT +T + P+ P + + T + + P T+P T
Sbjct: 2584 TTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWIST---- 2639
Query: 989 KPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTER--CPP 1046
T PT + + + P + + +P +T T+V G+ T SST+ PP
Sbjct: 2640 -TTTPTTRGSTVTP-------SSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPP 2691
Query: 1047 NARYESCACPASCKSPRPSCGP 1068
+ + A+ + PS P
Sbjct: 2692 SLTTTATTITATGSTTNPSSTP 2713
Score = 57.4 bits (137), Expect = 2e-07
Identities = 100/431 (23%), Positives = 142/431 (32%), Gaps = 91/431 (21%)
Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
CS +GD Y TFDG +R G YV + E L G P +
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRP-----VVTR 131
Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSF--GG 2448
V+ G ++ G +++N Q+ +PY L V G Y+ LV++F G
Sbjct: 132 VVIKAQGLVLEASNG-SVLINGQREELPYS-RTGLLVEQSGD--YIKVSIRLVLTFLWNG 187
Query: 2449 RKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRF 2508
+A++ L Y GLCG+++ + A L FGN ++
Sbjct: 188 EDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ-FGNLQKLDGPTEQCPD 246
Query: 2509 PRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEP 2568
P +PA C+ E+ + R L P FA CH V
Sbjct: 247 PLPLPA-----------------GNCTDEEGICH-----RTLLGPA--FAECHALVDSTA 282
Query: 2569 FQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRPRGLRGP 2628
+ C DLC RC + + G+PR R P
Sbjct: 283 YLAACAQDLC-----------RCPTCP---------CATFVEYSRQCAHAGGQPRNWRCP 322
Query: 2629 LRGRLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEP 2688
PR C PL + +Q S T+ CS R LCE
Sbjct: 323 -----ELCPRTC-------PL--------NMQHQECGSPCTDTCSN-----PQRAQLCED 357
Query: 2689 FS-----CRAGEVCTLGNHT--QGCFPESPCLQNPCQNDGQCREQGATFTCECEVGYGGG 2741
C G CT+ + GC P C PC + G+ G +F C G
Sbjct: 358 HCVDGCFCPPGRSCTVLDDITHSGCLPLGQC---PCTHGGRTYSPGTSFNTTCSSCTCSG 414
Query: 2742 LCMEPRDAPPP 2752
+ +D P P
Sbjct: 415 GLWQCQDLPCP 425
Score = 56.2 bits (134), Expect = 4e-07
Identities = 117/573 (20%), Positives = 186/573 (32%), Gaps = 135/573 (23%)
Query: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPL---G 2280
C+ C D+D R +GA C P V S P GC +A IPL
Sbjct: 4976 CNQHC-DID-RFQGA---------CPTSPPPVSSAPLSSPSPAPGCDNA----IPLRQVN 5020
Query: 2281 KSWVSSGCT-EKCVCTGGAI-----QCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQC--S 2332
++W CT +CV + + C + H + + + C +C S
Sbjct: 5021 ETWTLENCTVARCVGDNRVVLLDPKPVANVTCVN-KHLPIKVSDPSQPCDFHYECECICS 5079
Query: 2333 VYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVI 2392
++G Y TFDG SY +G TYVL++ + + S++L
Sbjct: 5080 MWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNL----------------SLYLDNHY 5123
Query: 2393 TTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTL-WGQRLYLVTDFELVVSFGGRKN 2451
T + L ++ + M + L VT+ G+ L+ ++ VS G KN
Sbjct: 5124 CTASATAAAARCPRALSIHYKSMDIV------LTVTMVHGKEEGLILFDQIPVSSGFSKN 5177
Query: 2452 AV-----------ISLP-------------------SMYEGLVSGLCGNYDKNRKNDMML 2481
V + +P S++ G CG N+++D +
Sbjct: 5178 GVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQ 5237
Query: 2482 PSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLAS 2541
G + +W V + ++G A G T S +P
Sbjct: 5238 RDGTTAASCKDMAKTWLVP------------DSRKDGCWAPTG--TPPTASPAAPVSSTP 5283
Query: 2542 NSTQA-----CRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSA--QDPREQEELRCQVL 2594
T C ++ FA CH V P PF C+ D C + P + E ++
Sbjct: 5284 TPTPCPPQPLCDLMLSQ--VFAECHNLVPPGPFFNACISDHCRGRLEVPCQSLEAYAELC 5341
Query: 2595 SGHGVSSRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPL----A 2650
GV S + + L + C P + GP++ P C + P L
Sbjct: 5342 RARGVCSDWRGAT--GGLCDLTCPPTKVYKPCGPIQ------PATCNSRNQSPQLEGMAE 5393
Query: 2651 DCGCTSNGIYYQLGSSFLTEDC-------------------SQRCTCASSRI-LLCEPFS 2690
C C + I + + C Q C C + + C+P
Sbjct: 5394 GCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLP 5453
Query: 2691 CRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQC 2723
C A N P +NPC + C
Sbjct: 5454 CDAQGQPPPCNRPGFVTVTRPRAENPCCPETVC 5486
Score = 55.1 bits (131), Expect = 1e-06
Identities = 83/314 (26%), Positives = 120/314 (38%), Gaps = 50/314 (15%)
Query: 759 PTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIP 818
P+TP T +P T T KPT T T ST TPT +T+ T P
Sbjct: 1889 PSTPATSSTATPSS----TPGTTWILTKPTT-TATTTASTGSTATPT--STLRTAPPP-- 1939
Query: 819 MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLT-IPTEK 877
+ TT+ T+++ K T P P +T P + + T + +T IP+
Sbjct: 1940 --------KVLTTTATTPTVTSSKAT-PSSSPGTATALPALRSTATTPTATSVTPIPSSS 1990
Query: 878 LTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTIS 937
L + + +TT T T+ T P+ +PE T T T TT +
Sbjct: 1991 LGTTWTR----LSQTTTPTA--TMSTATPSSTPE---------TAHTSTVLTATATTTGA 2035
Query: 938 TEKLTIPTEKPTISPEKLTIPTEKPTISTEKP-TIPTEKLTIPTEKPTIPTEKPTIPTEK 996
T + P+ P + +PT T T P + P LT P T T PT
Sbjct: 2036 TGSVATPSSTPG-TAHTTKVPTTTTTGFTATPSSSPGTALTPPVWIST--TTTPTTRGST 2092
Query: 997 LTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTER--CPPNARYESCA 1054
+T P + TAT L +T T+V G+ T SST+ PP+ +
Sbjct: 2093 VTPSSIPGTTHTATVL----------TTTTTTVATGSMATPSSSTQTSGTPPSLTTTATT 2142
Query: 1055 CPASCKSPRPSCGP 1068
A+ + PS P
Sbjct: 2143 ITATGSTTNPSSTP 2156
Score = 52.4 bits (124), Expect = 6e-06
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 15/177 (8%)
Query: 543 PPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPK--EKPTIPTEKPTI 600
PP + + + + T L P T P ++ P+ TT PT+ + P + T
Sbjct: 1614 PPTTELETATTTTTQALFSTPQ-PTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTA 1672
Query: 601 STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTI----PSEKPTISTEKPTV 656
+T PT P+ S +PT+P + L + +P ++ PS+ PT++ PT
Sbjct: 1673 TTGGPTTPAG-----STEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLA---PTT 1724
Query: 657 PTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTIS 713
PT +T+ +EP+ + P++ +E + E T E T+ T S
Sbjct: 1725 MATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTS 1781
Score = 50.4 bits (119), Expect = 2e-05
Identities = 53/189 (28%), Positives = 76/189 (40%), Gaps = 27/189 (14%)
Query: 882 TEKPTIPIEETTISTEKLTIPTEKPTISP----EKPTISTEKPTIPTEKPTIPTEETTIS 937
T PT +E T +T + T +PT SP P +T PT+ +E T P +T+
Sbjct: 1612 TPPPTTELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTL-SEGLTSPRYTSTLG 1670
Query: 938 TEKLTIPT-----EKPTIS-------PEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTI 985
T PT +PT+ P + +P ++ T +P+ P PT PT
Sbjct: 1671 TATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQP------PTLAPTT 1724
Query: 986 PTEKPTIPT-EKLTALRPPHPSPTATGLAA-LVMSPHAPSTPMTSVILG--TTTTSRSST 1041
PT TA + P + A L + L S STP T + T TT+ T
Sbjct: 1725 MATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGT 1784
Query: 1042 ERCPPNARY 1050
RC P +
Sbjct: 1785 TRCQPKCEW 1793
Score = 43.9 bits (102), Expect = 0.002
Identities = 69/259 (26%), Positives = 91/259 (35%), Gaps = 38/259 (14%)
Query: 471 SPAGSPPIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFI 527
SP + P+W + P ++VT VP P L + T + VA G +
Sbjct: 3883 SPGTARTPPVWIST-TTTPTTSGSTVTPSSVPGTTHTPTVL-------TTTTTTVATGSM 3934
Query: 528 LI------NPGTCPVKVLPELPPVSPVSSTGPSETTGLTENP-----TISTKKPTVSIEK 576
GT P + + S+T PS T G T P T +T T S
Sbjct: 3935 ATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVT 3994
Query: 577 PSV---TTEKPTVPKEKPTI------PTEKPTISTEKPTIPSEKPNMP--SEKPTIPSEK 625
PS TT P VP T P+ T+ T + S +E T S
Sbjct: 3995 PSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHT 4054
Query: 626 PTILTEKPTIPSEKPTIPSEKPTI-STEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSI 684
P T T P + S P+ +TE P P+ TTP T TS K
Sbjct: 4055 PAATTG--TTQHSTPALSSPHPSSRTTESP--PSPGTTTPGHTTATSRTTATATPSKTRT 4110
Query: 685 PTEKPSIPTEKPTISMEET 703
T PS PT P ++ T
Sbjct: 4111 STLLPSSPTSAPITTVVTT 4129
Score = 43.5 bits (101), Expect = 0.003
Identities = 44/169 (26%), Positives = 59/169 (34%), Gaps = 15/169 (8%)
Query: 549 SSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIP 608
S+T PS T G T P + T T S T + T P T +T ++P
Sbjct: 3405 STTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTH-TPPVPNTTATTHGRSLP 3463
Query: 609 SEKPNMPSEKPTIPSEK---PTILTEKPTIPSEKP-----TIPSEKPTISTEKPTVPTEE 660
P+ T + T +TE T+ S P T P +S+ P+ T E
Sbjct: 3464 PSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTE 3523
Query: 661 P------TTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEET 703
TTP TS K T PS PT P ++ T
Sbjct: 3524 SPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTT 3572
Score = 42.4 bits (98), Expect = 0.007
Identities = 95/433 (21%), Positives = 140/433 (32%), Gaps = 57/433 (13%)
Query: 759 PTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTI----STEEPTTPTEETTIS--- 811
P P+ P SP+ + +P +PT T TEK T+ S T +T S
Sbjct: 1434 PCGPSPAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGP 1493
Query: 812 -TEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEK-PTISTEKPTIPTEKPTISPE 869
T PS P P + T +E +E+L +E I + + I +
Sbjct: 1494 VTVTPSAPGTTTCQPRCQWTEWFDEDYPKSEQLGGDVESYDKIRAAGGHLCQQPKDIECQ 1553
Query: 870 KLTIPTEKLTIPTEKPTIPI---------EETTISTEKLTIPTEKPTISPE--KPTISTE 918
+ P L +K + E+ + S + + +T
Sbjct: 1554 AESFPNWTLAQVGQKVHCDVHFGLVCRNWEQEGVFKMCYNYRIRVLCCSDDHCRGRATTP 1613
Query: 919 KPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTIS--TEKPTIPTEKL 976
PT E T T + ST + PT P ++ T PT+S P +
Sbjct: 1614 PPTTELETATTTTTQALFSTPQ---PTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLG 1670
Query: 977 TIPTEKPTIP--TEKPTIPTEKLTALRPPHPSPTATGLAALVMSPH----APSTPMTSVI 1030
T T PT P + +PT+P + L P TG AP+T TS
Sbjct: 1671 TATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRA 1730
Query: 1031 LGTTTTSRSS----TERCPPNARYESCACPASCKSPR--PSCGPLCREGCVCNPGFLFSD 1084
T T S +S T P E A +PR + PL N
Sbjct: 1731 RPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPL------TNTTTSQGT 1784
Query: 1085 NHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCR------CWPGSRVECQ--------IS 1130
C +++ D+ G E+ R CW +EC+ I
Sbjct: 1785 TRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSID 1844
Query: 1131 QCGTHTVCQLKNG 1143
Q G C L+ G
Sbjct: 1845 QVGQVLTCSLETG 1857
Score = 33.5 bits (75), Expect = 3.0
Identities = 20/75 (26%), Positives = 37/75 (49%), Gaps = 4/75 (5%)
Query: 654 PTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSI---PTEKPTISMEETIISTEKP 710
P P+ P T + + ++ EP +PT + TEK ++ P+ + T ++ S+ P
Sbjct: 1434 PCGPSPAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGP 1493
Query: 711 -TISPEKPTIPTEKP 724
T++P P T +P
Sbjct: 1494 VTVTPSAPGTTTCQP 1508
Score = 33.5 bits (75), Expect = 3.0
Identities = 30/115 (26%), Positives = 35/115 (30%), Gaps = 18/115 (15%)
Query: 1033 TTTTSRSSTERCPPNARYESCAC-PASCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQAS 1091
T T R+ CP C C +C P C P C G C
Sbjct: 5470 TVTRPRAENPCCPETV----CVCNTTTCPQSLPVCPPGQESICTQEEG------DCCPTF 5519
Query: 1092 SCN---CFYNNDYYEPGAEWFSPNCTEHCRCWPGS----RVECQISQCGTHTVCQ 1139
C C YN +Y GA + C C G V+CQ C T Q
Sbjct: 5520 RCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQ 5574
>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2852
Score = 241 bits (614), Expect = 1e-62
Identities = 285/1239 (23%), Positives = 454/1239 (36%), Gaps = 248/1239 (20%)
Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI- 1512
+R + +C P ++ S C +C +HPA C C N
Sbjct: 25 ERRLHRAKCAPSYLFS---CFNGGEC--VHPA-----------------FCDCRRFNATG 62
Query: 1513 -RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRP 1571
RCQ +Y + + C A G H TFDG ++ G +Y L
Sbjct: 63 PRCQM--------------VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 108
Query: 1572 CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT-VFDLSISLLRGCKVMLNGHRVALPV 1630
Q F + N+ + G + +AV + V + I L + +V G RV LP
Sbjct: 109 HEPEGQS--FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK--EVTHGGMRVQLPH 164
Query: 1631 WLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
+ R ++ + V++ + +DG+ V + + G GLCGN N + DD
Sbjct: 165 VMGSAR--LQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDD 222
Query: 1691 NLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG--KPSSCQEN--SMADAWNKNCAILI 1746
+ KL D ++ +W+ ++P +P Q+N +M + + C L+
Sbjct: 223 LVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ-CEALL 281
Query: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNR 1805
P PF CH V P ASC C + GD CR+L YA CAQAG+ WR +
Sbjct: 282 RP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 339
Query: 1806 TF-CPMRCPPGS-SYSPCSSPCPDTCSSINNPR-DCPKA-LPCAESCECQKGHILSGTSC 1861
C + C + +Y+ C + CP +C +PR C + + C + C C G I C
Sbjct: 340 LRQCTVHCKEKAFTYNECIACCPASC----HPRASCVDSEIACVDGCYCPNGLIFEDGGC 395
Query: 1862 VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLL 1921
V +C C + G+ +P G + C CTC+ C + C
Sbjct: 396 VAPAECPC-EFHGTLYPPGS--VVKEDCNT-CTCT-SGKWECSTAVCPAE---------- 440
Query: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEG 1981
C + G+ H+ +FDG ++ P C +L K + + F ++ ++
Sbjct: 441 ---------CSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAPCGL 487
Query: 1982 GTEAFRLHEVYIDIYD---AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038
+ + V + ++ QVTL + VL+ + +P + + SS++ V
Sbjct: 488 NQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVR 547
Query: 2039 IKIGVQVKFDGNHL-LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
+GV+V +D L L +++ + G+CG FN +D+ + P ++ F NS
Sbjct: 548 TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 607
Query: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAA--LRAPVWAQCAS 2155
WK +C L+ P + L+ A +A L ++A C++
Sbjct: 608 WKTLS---ACSPLVSGSPLDPCD-----------VHLQAASYSVQACSVLTGEMFAPCSA 653
Query: 2156 RIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
+ P+ C C G LC L + C+ GL C L C A
Sbjct: 654 FLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK 711
Query: 2216 SYTNCLPSCSPSCWDL--------DGRCEGAKVPSACAEGCICQPGYVLSE--DKCVPRS 2265
Y+ C+ C +C DL DG + ++ C EGC C P L D CVPR+
Sbjct: 712 EYSPCVAPCGRTCQDLASPEACGVDGGDDLSR--DECVEGCACPPDTYLDTQADLCVPRN 769
Query: 2266 QCG----------------------CKD--------AHGGSIPLGKSWVSSG-------- 2287
QC CKD A + P G+ +V+
Sbjct: 770 QCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLEL 829
Query: 2288 --------------------CTEKCVCTGGAIQCGDF-----RCP--------------- 2307
C C C G ++ GD CP
Sbjct: 830 SRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM 889
Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
S H + S + + C+ YGD Y TFDG + G L+K+ +
Sbjct: 890 SPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFS 949
Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL-- 2425
V +VE N S + ++ I+ + G L+V + P P L
Sbjct: 950 V---IVENVNCYS---SGMICRKFIS--------INVGNSLIVFDDDSGNP-SPESFLDD 994
Query: 2426 --RVTLWGQRLYLVTDF---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMM 2480
V W + + F + + + R + ++G ++GLCGN+D N+M
Sbjct: 995 KQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1054
Query: 2481 LPSGALTQNLNTFGNSW-EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQL 2539
P N FG+SW V+ D L PR + LR ECS
Sbjct: 1055 TPENLELTNPQEFGSSWAAVECPDTL--DPRDMCVLNP-------LREPFAKKECS---- 1101
Query: 2540 ASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLC 2578
+L++ F CH V F +C+ D C
Sbjct: 1102 --------ILLSE---VFEICHPVVDVTWFYSNCLTDTC 1129
Score = 230 bits (586), Expect = 2e-59
Identities = 201/752 (26%), Positives = 299/752 (39%), Gaps = 77/752 (10%)
Query: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILA---QPCGNSTDPFFRVTAKNEEQ-GQEGVSCL 1211
C +G H TFDG ++ GK +Y L +P G S F + N+ Q G +C
Sbjct: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS----FSIQVHNDPQCGSSPYTCS 134
Query: 1212 SKVYVT-LPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWD 1270
V + + E + L K GG +V LP + +G +V ++ + + WD
Sbjct: 135 RAVSLFFVGEQEIHLAK--EVTHGGMRVQLPHVMGSARLQQLAG-YVIVRHQSAFTLAWD 191
Query: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330
G +Y+ +S G GLCGN + + +D + G D E +SWQ
Sbjct: 192 GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 251
Query: 1331 QKYQVVNSPSCDSSLQSSMSGP-GFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
+ P C +M G C L+ PF+ C +V F SC D+C
Sbjct: 252 PTTSSLPRPPCLQQNPGTMQGVYEQCEALL--RPPFDACHAYVSPLPFTASCTSDLCQSM 309
Query: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWR-EPHFCPMACPPNS-KYSLCAKPCPDTCHSGF 1447
G C ++ C AG ++ WR + C + C + Y+ C CP +CH
Sbjct: 310 GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRA 369
Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVGERWYKPGCKE 1502
S + CV+ C C G + C+ ++C C L+P GS K C
Sbjct: 370 SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV-------VKEDC-N 421
Query: 1503 LCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562
C C S W C A A C+ +GD H+ TFDG + F
Sbjct: 422 TCTCTSGK------WECST--------------AVCPAECSVTGDIHFTTFDGRRYTFPA 461
Query: 1563 TCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFD---LSISLLRGCKV 1619
TC Y+L + SRS + F V+ N G + + +++V V + ++L + V
Sbjct: 462 TCQYILAK---SRSSGT-FTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDV 517
Query: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHL-VEVTVPSSYGGQLCG 1678
+L +P + RLSS + + TN G++V YD L + + V + G
Sbjct: 518 LLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVG 577
Query: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP-SSCQENSMADA 1737
LCG +N N+ DD L P G +WK + P LV G P C + A +
Sbjct: 578 LCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP---LVSGSPLDPCDVHLQAAS 634
Query: 1738 WN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796
++ + C++L F+ C + P F C C + LC +L YA LC +
Sbjct: 635 YSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRH 690
Query: 1797 GQAPAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP-------KALPCAESC 1848
G +R R C + C YSPC +PC TC + +P C C E C
Sbjct: 691 GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC 750
Query: 1849 ECQKGHILSGTS--CVPLGQCGCTDPAGSYHP 1878
C L + CVP QC C Y P
Sbjct: 751 ACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP 782
Score = 179 bits (454), Expect = 3e-44
Identities = 144/476 (30%), Positives = 196/476 (41%), Gaps = 63/476 (13%)
Query: 1032 GTTTTSRSSTERCPPNA-RYESC--ACPASCKSPRPSCGP---LCREGCVCNPGFLFSDN 1085
G T R T C A Y C CPASC PR SC C +GC C G +F D
Sbjct: 335 GWRTQLRQCTVHCKEKAFTYNECIACCPASCH-PRASCVDSEIACVDGCYCPNGLIFEDG 393
Query: 1086 HCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY 1145
C+ + C C ++ Y PG+ E C C +G++
Sbjct: 394 GCVAPAECPCEFHGTLYPPGSV-----VKEDCN------------------TCTCTSGKW 430
Query: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG- 1204
C A C V GD H+ TFDGR + F C YILA+ + T F VT +N G
Sbjct: 431 ECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGT---FTVTLQNAPCGL 487
Query: 1205 -QEGVSCLSKVYVTL---PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL-GASGRFVEL 1259
Q+G +C+ V V L P VTL + L+ Q +P + S F+ +
Sbjct: 488 NQDG-ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRV 546
Query: 1260 QTEFGLRVRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGN 1318
+T G+RV +D + +LY+ V + GLCG ++GN+ +D L G P + GN
Sbjct: 547 RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 606
Query: 1319 SWQTDQDEDQECQKYQVVNSP--SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAAS 1376
SW+T C V SP CD LQ++ C L T F C +
Sbjct: 607 SWKT----LSACSPL-VSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVP 659
Query: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436
+F+ C D C + Q LC ++ C+ G V C ++C + +YS C
Sbjct: 660 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
Query: 1437 KPCPDTCHSGFSGMFCS---------DRCVEACECNPGFVLSGLE--CIPRSQCGC 1481
PC TC S C D CVE C C P L C+PR+QC C
Sbjct: 718 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 773
Score = 164 bits (414), Expect = 1e-39
Identities = 201/850 (23%), Positives = 306/850 (36%), Gaps = 170/850 (20%)
Query: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
+C+ G+ H +FDG + + + LV P F I H + G+ +
Sbjct: 78 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS--FSIQV-HNDPQCGSSPYTCS 134
Query: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049
+ + + V +V LP + + ++ + Y IV + + +DG
Sbjct: 135 RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHV--MGSARLQQLAGYVIVRHQSAFTLAWDG 192
Query: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID----P 2105
+ I++ G G+CGN N + +D+L+ S ++ + EFV+SW+++ + P
Sbjct: 193 ASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP 252
Query: 2106 SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 2165
+ SL P Q+NP ++ E+CEA LR P A C + + PF
Sbjct: 253 TTSSL-----PRPPCLQQNPG------TMQGVYEQCEALLRPPFDA-CHAYVSPLPFTAS 300
Query: 2166 CANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYS-SYTNCLPS 2223
C + LC+ G C+AL + C G WR C + C + +Y C+
Sbjct: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
Query: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSW 2283
C SC C +++ AC +GC C G + + CV ++C C + HG P G S
Sbjct: 361 CPASCHPR-ASCVDSEI--ACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPG-SV 415
Query: 2284 VSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFD 2343
V C C CT G +C CP+ +CSV GD + TFD
Sbjct: 416 VKEDCNT-CTCTSGKWECSTAVCPA---------------------ECSVTGDIHFTTFD 453
Query: 2344 GFSYRLQGRMTYVLIK---------TVDVLPEGV--EPLLVEGRNKM--DPPRSSIFLQE 2390
G Y Y+L K T+ P G+ + V+ + + PR + L
Sbjct: 454 GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTL-- 511
Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPY-----------------RPNEHLRVTL--WG 2431
QAG L+ + K+ PY R N +RV G
Sbjct: 512 -----------TQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560
Query: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491
RLYL D V GLCG ++ N ++D + P G
Sbjct: 561 LRLYLQVDQRWVED------------------TVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
Query: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVL 2550
FGNSW+ + A L +G + C Q AS S QAC VL
Sbjct: 603 LFGNSWKTLS-------------------ACSPLVSGSPLDPCDVHLQAASYSVQACSVL 643
Query: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYD 2610
FA C ++P P+ E C D C P C L+ + R H
Sbjct: 644 TGEM--FAPCSAFLSPVPYFEQCRRDACRCGQP-----CLCATLAHYAHLCRRH------ 690
Query: 2611 TLPSILCQPGRPRGLRGPLRGRLRQHPRLC-LQWHPEPPLADCGCTSNGIY------YQL 2663
GL R RL C P +A CG T +
Sbjct: 691 -------------GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDG 737
Query: 2664 GSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQC 2723
G ++C + C C L + C C+ H QG + P + + G C
Sbjct: 738 GDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC--HFQGV--DYPPGDSDIPSLGHC 793
Query: 2724 REQGATFTCE 2733
+ +C+
Sbjct: 794 HCKDGVMSCD 803
Score = 152 bits (383), Expect = 6e-36
Identities = 234/1056 (22%), Positives = 367/1056 (34%), Gaps = 235/1056 (22%)
Query: 598 PTISTEKPTIPSEKPNMPSEK-PTIPSEKPTILTEKPTIPSEKPTIPSEKP-TISTEKPT 655
PT + T+P PS+ PT E+P + E P P+ +P + P T + P
Sbjct: 1399 PTEALGNETLP------PSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1452
Query: 656 VPTEEPTTPTEETTTSMEEPVIPT--EKPSIPTEKPS---------------------IP 692
TEEP T T++++P+ T + P+ PTE P+ +
Sbjct: 1453 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVA 1512
Query: 693 TEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKSTISPEKPT 739
+ PT M + T + T+ SP P P + P + T
Sbjct: 1513 LQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTT 1572
Query: 740 TPTEKPTI-PTEKPTISP----EKPT---------TPTEKPTISPEKLTIPTEKPTIPTE 785
P T P+ +P SP PT TP IS + PT+ +
Sbjct: 1573 PPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS--AS 1630
Query: 786 KPTIP-TEKPTISTEEPTTPTE----ETTISTEKP----SIPMEKPTLPTEETTTSV--- 833
P+ P T T + + P +P E +STEK S PM P P S
Sbjct: 1631 SPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR 1690
Query: 834 --EETTISTEKLTIPMEKP---TISTE------------KPTIPTEKPTISPEKLTIPTE 876
+ TT++T +P E P ++ST + T P++ + P ++P
Sbjct: 1691 PAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLA 1750
Query: 877 KL----TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKP----TISTEKP-------- 920
K+ + T P + T + + T+P + T+SP P ++ P
Sbjct: 1751 KVGTSAPVATPGPKASVITTPLQPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPA 1808
Query: 921 -----------TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTE------ 960
T+PT +P E T S + T K I +++++PT
Sbjct: 1809 AGTAPGLLLGATLPTSG-VLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAE 1867
Query: 961 ----KPTISTEKPTIPT----------EKLTIPTEKPTIPTEKPTIPTEKLTALRPP--- 1003
+ T +T P P L +PT T P + + L P
Sbjct: 1868 GGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAE 1927
Query: 1004 -HPSPTATGLAA-----LVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPA 1057
H + LAA P S P S++ G ++TE
Sbjct: 1928 AHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEA-------------- 1973
Query: 1058 SCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHC 1117
+ +C P+ + CV + C++ + N ++HC
Sbjct: 1974 ---NTSTTCVPIAEQDCV--------RHICLEG----------------QLIRVNQSQHC 2006
Query: 1118 RCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGK 1177
P +CG + G C + C ++ D +VTFDG H +
Sbjct: 2007 ---PQGAAP---PRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKE 2060
Query: 1178 CTYILAQPCGNSTDPFFRVTAKNEEQGQEG-----VSCLSKVYVTLPESTVTLLKGRRTL 1232
YIL+Q S D V + + G CL + +T VT+ + R +
Sbjct: 2061 AIYILSQ----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKV 2116
Query: 1233 VGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRW-DGDQQLYVTVSSTYSGKLCGLC 1291
Q P + G + +G + T ++++W + V S T + GLC
Sbjct: 2117 TVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLC 2176
Query: 1292 GNYDGNSDNDHLKLDGSPAGDKEELG---NSWQTDQDEDQECQ-KYQVVNSPSCDSSLQS 1347
G DG++ ND DGS G E+ +SWQ Q +++ + + D S
Sbjct: 2177 GICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSP-- 2234
Query: 1348 SMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQ 1407
C R+V ++ F C V SF + + D Q C ++ C
Sbjct: 2235 -------CLRMV-SNRTFSACHRFVPPESFCELWIRDTKYVQ----QPCVALTVYVAMCH 2282
Query: 1408 DAGHAVKPWREPHFCPMACPPNSKYSLCAKPC--PDTCHSGFSGMFCSDRCV---EACEC 1462
H WR +CP C +S Y C C P TC G G + C E C C
Sbjct: 2283 KF-HVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVC 2341
Query: 1463 NPGFVL---SGLECIPRSQCGCLHPAGSYFKVGERW 1495
+ G +L CIP ++C C G +GE W
Sbjct: 2342 SEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2377
Score = 108 bits (269), Expect = 1e-22
Identities = 102/406 (25%), Positives = 158/406 (38%), Gaps = 63/406 (15%)
Query: 1425 ACPPNSKYSLCAKPCPD-------TCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIP 1475
ACP + C+ D TC + S R C+ C C G + G C
Sbjct: 810 ACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFL 869
Query: 1476 RSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH 1535
+C C YF G++ P C CVC+ + +C C
Sbjct: 870 PEECPCTWKGKEYFP-GDQVMSP-C-HTCVCQRGS-FQCTLHPC---------------- 909
Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
A+TCTA GD HY TFDG F+G C L + + D F V N N
Sbjct: 910 ---ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKS----TSDVSFSVIVENVN------ 956
Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTI---RLSSNLVLLYTNF 1652
Y + F +SI++ V + P + + R+ ++ +
Sbjct: 957 -CYSSGMICRKF-ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQE 1014
Query: 1653 GLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW--- 1709
+ + +D V V + GQL GLCGN++ ++++ P+ + + G++W
Sbjct: 1015 HITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV 1074
Query: 1710 KLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASC 1768
+ P++ +P C N + + + K C+IL++ F CH VV +++C
Sbjct: 1075 ECPDTLDPR--------DMCVLNPLREPFAKKECSILLSEV--FEICHPVVDVTWFYSNC 1124
Query: 1769 VHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812
+ CG GD C S+ AYA C Q G A WR CP C
Sbjct: 1125 LTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170
Score = 107 bits (268), Expect = 1e-22
Identities = 100/406 (24%), Positives = 147/406 (36%), Gaps = 55/406 (13%)
Query: 1037 SRSSTERCPPNARYESCA-------------CPASCKSPRPSCGPLCREGCVCNPGFLFS 1083
SR+ CP + +C+ C + S C GC C G L
Sbjct: 804 SRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRH 863
Query: 1084 DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143
+ C C C + Y PG + SP C T VCQ +
Sbjct: 864 GDACFLPEECPCTWKGKEYFPGDQVMSP--------------------CHT-CVCQRGSF 902
Query: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203
Q HP A +TC YGD HY TFDG F F+G C L + +++D F V +N
Sbjct: 903 QCTLHPCA--STCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STSDVSFSVIVENVNC 957
Query: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ-TE 1262
G+ C + + + S + G + V G F + +
Sbjct: 958 YSSGMICRKFISINVGNSLIVFDDDS----GNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1013
Query: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322
+ + WD ++V + G+L GLCGN+D + N+ + + +E G+SW
Sbjct: 1014 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1073
Query: 1323 DQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCM 1382
+ D + V +P + + C L+ FE C V F+ +C+
Sbjct: 1074 VECPDTLDPRDMCVLNPLREPFAKKE------CSILLSE--VFEICHPVVDVTWFYSNCL 1125
Query: 1383 LDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
D CG G C +S C G AV WR P CP C
Sbjct: 1126 TDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 93.2 bits (230), Expect = 3e-18
Identities = 93/378 (24%), Positives = 147/378 (38%), Gaps = 69/378 (18%)
Query: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSY 1598
A C+ D ++TFDG+ Y+L S+S D V + + +++
Sbjct: 2036 ACRCSIFPDLSFVTFDGSHVALFKEAIYIL-----SQSPDEMLTVHVLDCKSANLGHLNW 2090
Query: 1599 IKAVHVTVFDLSISLLRGCKVMLN----GHRVAL------------PVWLAQGRVTIRL- 1641
C VMLN H+V + PVW R R+
Sbjct: 2091 PPF---------------CLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIE 2135
Query: 1642 -SSNLVLLYTNFGLQVRY---DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697
+ ++ ++ T +Q+++ G +VE + S G GLCG + ++ +D D
Sbjct: 2136 DTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGS 2193
Query: 1698 LAG---DSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQ 1754
+ G D +W++P SS +P SC + C +++ + FS
Sbjct: 2194 VVGGAEDPAPFLDSWQVP-SSLTSVGQTRFRPDSCATTDCSP-----CLRMVSNR-TFSA 2246
Query: 1755 CHQVVPPQSSFASCVHGQCGTKGDTTAL---CRSLQAYASLCAQAGQAPAWRNRTFCPMR 1811
CH+ VPP+S + DT + C +L Y ++C + WR +CP
Sbjct: 2247 CHRFVPPESFCELWIR-------DTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL 2299
Query: 1812 CPPGSSYSPCSSPC--PDTC-SSINNPRDCPKALPCAESCECQKGHIL---SGTSCVPLG 1865
C S+Y C + C P TC I P D E C C +G IL C+P
Sbjct: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2359
Query: 1866 QCGCTDPAGSYHPVGERW 1883
+C CTD G +GE W
Sbjct: 2360 KCACTDSMGVPRALGETW 2377
Score = 80.5 bits (197), Expect = 2e-14
Identities = 107/485 (22%), Positives = 175/485 (36%), Gaps = 60/485 (12%)
Query: 569 KPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM-PSEKPTIPSEKPT 627
+P V + ++ E + PT E+P +S E P P+ +P + P+ T P
Sbjct: 1393 EPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1452
Query: 628 ILTEKPTIP--SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685
TE+P + + T+ +++ P PTE P ++ T S+ E S+P
Sbjct: 1453 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPA--SKGVTASLLAIPHTPESSSLP 1510
Query: 686 TEKPSIPTEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKST 732
+ + PT M + T + T+ SP P P +
Sbjct: 1511 -----VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHG 1565
Query: 733 ISPEKPTTPTEKPTI-PTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPT 791
P + T P T P+ +P S P + PT S + T T + +P
Sbjct: 1566 SLPVRTTPPQPSLTASPSSRPVAS---PGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQ 1622
Query: 792 EKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPT 851
S P+TP + E+ +P T E +STEK +P
Sbjct: 1623 PTQAQSASSPSTPLTVAGTAAEQ---------VPVSPLATRSLEIVLSTEKGEAGHSQPM 1673
Query: 852 ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911
S P P P+ P P + T+ T P +P E T + L+ T+ +P
Sbjct: 1674 GSPASPQ-PHPLPSAPPR----PAQHTTMATRSPALPPE--TPAAASLSTATDGLAATPF 1726
Query: 912 KPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTI 971
ST + + P +T++ K + T P +P P S +
Sbjct: 1727 MSLESTRPSQLLSGLP----PDTSLPLAK--VGTSAPVATP--------GPKASVITTPL 1772
Query: 972 PTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA-ALVMSPHAPSTPMTSVI 1030
+ T+P + T+ P P A P H +P A G A L++ P++ + V
Sbjct: 1773 QPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVA 1830
Query: 1031 LGTTT 1035
GT +
Sbjct: 1831 EGTAS 1835
Score = 76.6 bits (187), Expect = 3e-13
Identities = 87/428 (20%), Positives = 153/428 (35%), Gaps = 88/428 (20%)
Query: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTSCV 1862
CP G + CS D ++ R C + L PC C C +G + G +C
Sbjct: 811 CPAGQVFVNCSDLHTDL--ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 868
Query: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922
+C CT Y P + +TC C + FQ T P
Sbjct: 869 LPEECPCTWKGKEYFPGDQVMSPCHTCV----CQRGS----FQCTLHP------------ 908
Query: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982
C ++ C G+ HY +FDG AC + LVK
Sbjct: 909 CAST----CTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV------------------ 946
Query: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042
+F + ++ Y + + +K + + + + S P + ++G
Sbjct: 947 --SFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1004
Query: 2043 -----------VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSD 2091
+ + +D + ++ + G++ G+CGNF+ + +E+ P + +
Sbjct: 1005 FFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNP 1064
Query: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPV 2149
EF +SW + C L +P C LR A+++C + L + V
Sbjct: 1065 QEFGSSWAAVE----CPDTL------------DPRDMCVLNPLREPFAKKEC-SILLSEV 1107
Query: 2150 WAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2207
+ C +D+T F +C C GG + C ++ A+ C G+ WR C
Sbjct: 1108 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLC 1166
Query: 2208 PLECPAYS 2215
P +C ++
Sbjct: 1167 PYDCDFFN 1174
Score = 76.3 bits (186), Expect = 4e-13
Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 35/322 (10%)
Query: 1999 QVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF-DGNHLLEIEI 2057
QVT+ + +R + Q P +S+ G ++ + ++ +Q+++ + L+ +E
Sbjct: 2106 QVTIDRFNRKVTVDLQPVWPPVSRY-GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEA 2164
Query: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEV---ANSDSEFVNSWKDKDIDPSCQSLLVDE 2114
T + G+CG + + ++L + V A + F++SW+ PS + +
Sbjct: 2165 SKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQT 2220
Query: 2115 QQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFG 2174
+ P C R C + P + C I T ++
Sbjct: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFV--PPESFCELWIRDTKYV----------- 2267
Query: 2175 GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR 2234
Q C AL + A C + WR S +CP C + S+Y C+ +C P DG
Sbjct: 2268 ---QQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG- 2322
Query: 2235 CEGAKVPSAC---AEGCICQPGYVLSEDK---CVPRSQCGCKDAHGGSIPLGKSWVS--S 2286
G P C EGC+C G +L C+P ++C C D+ G LG++W S S
Sbjct: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
Query: 2287 GCTEKCVCTGGAIQCGDFRCPS 2308
GC + I D CPS
Sbjct: 2383 GCCQHQCQAPDTIVPVDLGCPS 2404
Score = 75.1 bits (183), Expect = 9e-13
Identities = 93/442 (21%), Positives = 152/442 (34%), Gaps = 86/442 (19%)
Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
+G CQ+ N ++ C +G TFDG Y L G+ +Y L+ + PEG
Sbjct: 61 TGPRCQMVY-----NAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHE--PEG 113
Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRV 2427
+ ++ N S ++ + + ++ E+ ++ +P+
Sbjct: 114 -QSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ 172
Query: 2428 TLWGQRLYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGA 2485
L G Y++ + +++ G I + G GLCGN + + K+D++ SG
Sbjct: 173 QLAG---YVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGK 229
Query: 2486 LTQNLNTFGNSWEVKTED-----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLA 2540
LT ++ F +SW+ + + PR P ++ G G+
Sbjct: 230 LTDDVVEFVHSWQEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGV--------------- 273
Query: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVS 2600
+ C L P PF ACH V+P PF C DLC + C+ L+ +
Sbjct: 274 ---YEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMG---DVATWCRALAEYA-- 323
Query: 2601 SRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIY 2660
Q GRP L+G W + C
Sbjct: 324 -------------RACAQAGRP--LQG---------------WRTQLRQCTVHCKEKAFT 353
Query: 2661 YQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQND 2720
Y + C R +C S I + C G + G GC + C PC+
Sbjct: 354 YNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG----GCVAPAEC---PCEFH 406
Query: 2721 GQCREQGATF-----TCECEVG 2737
G G+ TC C G
Sbjct: 407 GTLYPPGSVVKEDCNTCTCTSG 428
Score = 74.7 bits (182), Expect = 1e-12
Identities = 109/472 (23%), Positives = 174/472 (36%), Gaps = 95/472 (20%)
Query: 647 PTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIS 706
P + P PT + + +E+ V P +PTE T P+ +
Sbjct: 1363 PRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAVW--VPTEALGNETLPPSQGL------ 1414
Query: 707 TEKPTISPEKPTIPTEKPTIPTEKSTISPEKP-TTPTEKPTIPTEKPTISP--------- 756
PT S E+P + E P PT + ++P P TT P TE+P +SP
Sbjct: 1415 ---PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQ 1471
Query: 757 -------EKPTTPTEKPT---ISPEKLTIP--TEKPTIPTEKPTIPTEKPTISTEEPTTP 804
+ P PTE P ++ L IP E ++P T PT E T
Sbjct: 1472 PLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQT-PTPGMVSGAMETTRV 1530
Query: 805 T------EETTISTEKPSIPMEKPTLPTEETT----------TSVEETTISTEKLTIPME 848
T T+S+ P P + L T+ T T+ + +++ + P+
Sbjct: 1531 TVIFAGSPNITVSSRSP--PAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVA 1588
Query: 849 KPTISTEKPTIP-TEKPTISP-----------------EKLTIPTEKLTIP-TEKPTIPI 889
P + PT + K ++P + + P+ LT+ T +P+
Sbjct: 1589 SPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPV 1648
Query: 890 EETTISTEKLTIPTEKPTISPEKPTISTEKP---TIPTEKPTIPTEETTISTEKLTIPTE 946
+ ++ + TEK +P S P +P+ P P + TT++T +P E
Sbjct: 1649 SPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR-PAQHTTMATRSPALPPE 1707
Query: 947 KPTISPEKLTIPTE----KPTISTEKPTIPTEKLTIPTEKPTIPTEK------PTIPTEK 996
P + L+ T+ P +S E T P++ L+ ++P K P K
Sbjct: 1708 TPAAA--SLSTATDGLAATPFMSLES-TRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPK 1764
Query: 997 LTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNA 1048
+ + P P AT L A +SP P TP T + T PP A
Sbjct: 1765 ASVITTP-LQPQATTLPAQTLSPVLPFTP------AAMTQAHPPTHIAPPAA 1809
Score = 49.7 bits (117), Expect = 4e-05
Identities = 119/546 (21%), Positives = 192/546 (35%), Gaps = 107/546 (19%)
Query: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284
+P+ ++G E + C P ++E CV C + + +
Sbjct: 1954 APALSIVEGLAEALATTTEANTSTTCVP---IAEQDCVRHI---CLEGQLIRVNQSQHCP 2007
Query: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344
+C G A++ G RC C +CS++ D ++TFDG
Sbjct: 2008 QGAAPPRCGILGLAVRVGGDRCCPLWECAC---------------RCSIFPDLSFVTFDG 2052
Query: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMD---PPRSSIFLQEVITTVYGYKVQ 2401
L Y+L ++ D + V L + N PP + L T ++V
Sbjct: 2053 SHVALFKEAIYILSQSPDEMLT-VHVLDCKSANLGHLNWPPFCLVMLN---MTHLAHQVT 2108
Query: 2402 LQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI---SLPS 2458
+ V + + P R+ G ++T ++ + + +I S S
Sbjct: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
Query: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALT---QNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
+G GLCG D + ND+ L G++ ++ F +SW+V P+
Sbjct: 2169 KAQG--HGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------------PSS 2213
Query: 2516 EEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
G ++CSP ++ SN T F+ACH+ V PE F E +
Sbjct: 2214 LTSVGQTRFRPDSCATTDCSPCLRMVSNRT------------FSACHRFVPPESFCELWI 2261
Query: 2575 LDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPS---------ILCQPGR--PR 2623
D Q P + + V + S+ L S C+P +
Sbjct: 2262 RDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQD 2321
Query: 2624 GLRGPL---------------RGRL--RQHPRLCLQWHPEPPLADCGCT-SNGIYYQLG- 2664
G+ GPL G + R+H LC+ P A C CT S G+ LG
Sbjct: 2322 GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCI------PEAKCACTDSMGVPRALGE 2375
Query: 2665 --SSFLTEDCSQRCTCASSRI---LLC---EPFSC-RAGEVCTLGNHTQGCFPESPCLQN 2715
+S L+ C +C + + L C P SC R GEV L C + C+ N
Sbjct: 2376 TWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2435
Query: 2716 PCQNDG 2721
+G
Sbjct: 2436 QTLCEG 2441
Score = 32.7 bits (73), Expect = 5.2
Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 19/95 (20%)
Query: 1044 CPPNARYESCACPA--SCK---SPRPSCG---------PLCREGCVCNPGFLFSDNH--C 1087
C + Y C P +C+ SP +CG C EGC C P C
Sbjct: 707 CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 765
Query: 1088 IQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPG 1122
+ + C+C + Y PG HC C G
Sbjct: 766 VPRNQCSCHFQGVDYPPGDS--DIPSLGHCHCKDG 798
>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2924
Score = 241 bits (614), Expect = 1e-62
Identities = 285/1239 (23%), Positives = 454/1239 (36%), Gaps = 248/1239 (20%)
Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI- 1512
+R + +C P ++ S C +C +HPA C C N
Sbjct: 97 ERRLHRAKCAPSYLFS---CFNGGEC--VHPA-----------------FCDCRRFNATG 134
Query: 1513 -RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRP 1571
RCQ +Y + + C A G H TFDG ++ G +Y L
Sbjct: 135 PRCQM--------------VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 180
Query: 1572 CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT-VFDLSISLLRGCKVMLNGHRVALPV 1630
Q F + N+ + G + +AV + V + I L + +V G RV LP
Sbjct: 181 HEPEGQS--FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK--EVTHGGMRVQLPH 236
Query: 1631 WLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
+ R ++ + V++ + +DG+ V + + G GLCGN N + DD
Sbjct: 237 VMGSAR--LQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDD 294
Query: 1691 NLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG--KPSSCQEN--SMADAWNKNCAILI 1746
+ KL D ++ +W+ ++P +P Q+N +M + + C L+
Sbjct: 295 LVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ-CEALL 353
Query: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNR 1805
P PF CH V P ASC C + GD CR+L YA CAQAG+ WR +
Sbjct: 354 RP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 411
Query: 1806 TF-CPMRCPPGS-SYSPCSSPCPDTCSSINNPR-DCPKA-LPCAESCECQKGHILSGTSC 1861
C + C + +Y+ C + CP +C +PR C + + C + C C G I C
Sbjct: 412 LRQCTVHCKEKAFTYNECIACCPASC----HPRASCVDSEIACVDGCYCPNGLIFEDGGC 467
Query: 1862 VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLL 1921
V +C C + G+ +P G + C CTC+ C + C
Sbjct: 468 VAPAECPC-EFHGTLYPPGS--VVKEDCNT-CTCT-SGKWECSTAVCPAE---------- 512
Query: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEG 1981
C + G+ H+ +FDG ++ P C +L K + + F ++ ++
Sbjct: 513 ---------CSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAPCGL 559
Query: 1982 GTEAFRLHEVYIDIYD---AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038
+ + V + ++ QVTL + VL+ + +P + + SS++ V
Sbjct: 560 NQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVR 619
Query: 2039 IKIGVQVKFDGNHL-LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
+GV+V +D L L +++ + G+CG FN +D+ + P ++ F NS
Sbjct: 620 TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 679
Query: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAA--LRAPVWAQCAS 2155
WK +C L+ P + L+ A +A L ++A C++
Sbjct: 680 WKTLS---ACSPLVSGSPLDPCD-----------VHLQAASYSVQACSVLTGEMFAPCSA 725
Query: 2156 RIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
+ P+ C C G LC L + C+ GL C L C A
Sbjct: 726 FLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK 783
Query: 2216 SYTNCLPSCSPSCWDL--------DGRCEGAKVPSACAEGCICQPGYVLSE--DKCVPRS 2265
Y+ C+ C +C DL DG + ++ C EGC C P L D CVPR+
Sbjct: 784 EYSPCVAPCGRTCQDLASPEACGVDGGDDLSR--DECVEGCACPPDTYLDTQADLCVPRN 841
Query: 2266 QCG----------------------CKD--------AHGGSIPLGKSWVSSG-------- 2287
QC CKD A + P G+ +V+
Sbjct: 842 QCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLEL 901
Query: 2288 --------------------CTEKCVCTGGAIQCGDF-----RCP--------------- 2307
C C C G ++ GD CP
Sbjct: 902 SRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM 961
Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
S H + S + + C+ YGD Y TFDG + G L+K+ +
Sbjct: 962 SPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFS 1021
Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL-- 2425
V +VE N S + ++ I+ + G L+V + P P L
Sbjct: 1022 V---IVENVNCYS---SGMICRKFIS--------INVGNSLIVFDDDSGNP-SPESFLDD 1066
Query: 2426 --RVTLWGQRLYLVTDF---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMM 2480
V W + + F + + + R + ++G ++GLCGN+D N+M
Sbjct: 1067 KQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1126
Query: 2481 LPSGALTQNLNTFGNSW-EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQL 2539
P N FG+SW V+ D L PR + LR ECS
Sbjct: 1127 TPENLELTNPQEFGSSWAAVECPDTL--DPRDMCVLNP-------LREPFAKKECS---- 1173
Query: 2540 ASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLC 2578
+L++ F CH V F +C+ D C
Sbjct: 1174 --------ILLSE---VFEICHPVVDVTWFYSNCLTDTC 1201
Score = 230 bits (586), Expect = 2e-59
Identities = 201/752 (26%), Positives = 299/752 (39%), Gaps = 77/752 (10%)
Query: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILA---QPCGNSTDPFFRVTAKNEEQ-GQEGVSCL 1211
C +G H TFDG ++ GK +Y L +P G S F + N+ Q G +C
Sbjct: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS----FSIQVHNDPQCGSSPYTCS 206
Query: 1212 SKVYVT-LPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWD 1270
V + + E + L K GG +V LP + +G +V ++ + + WD
Sbjct: 207 RAVSLFFVGEQEIHLAK--EVTHGGMRVQLPHVMGSARLQQLAG-YVIVRHQSAFTLAWD 263
Query: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330
G +Y+ +S G GLCGN + + +D + G D E +SWQ
Sbjct: 264 GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 323
Query: 1331 QKYQVVNSPSCDSSLQSSMSGP-GFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
+ P C +M G C L+ PF+ C +V F SC D+C
Sbjct: 324 PTTSSLPRPPCLQQNPGTMQGVYEQCEALL--RPPFDACHAYVSPLPFTASCTSDLCQSM 381
Query: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWR-EPHFCPMACPPNS-KYSLCAKPCPDTCHSGF 1447
G C ++ C AG ++ WR + C + C + Y+ C CP +CH
Sbjct: 382 GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRA 441
Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVGERWYKPGCKE 1502
S + CV+ C C G + C+ ++C C L+P GS K C
Sbjct: 442 SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV-------VKEDC-N 493
Query: 1503 LCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562
C C S W C A A C+ +GD H+ TFDG + F
Sbjct: 494 TCTCTSGK------WECST--------------AVCPAECSVTGDIHFTTFDGRRYTFPA 533
Query: 1563 TCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFD---LSISLLRGCKV 1619
TC Y+L + SRS + F V+ N G + + +++V V + ++L + V
Sbjct: 534 TCQYILAK---SRSSGT-FTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDV 589
Query: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHL-VEVTVPSSYGGQLCG 1678
+L +P + RLSS + + TN G++V YD L + + V + G
Sbjct: 590 LLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVG 649
Query: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP-SSCQENSMADA 1737
LCG +N N+ DD L P G +WK + P LV G P C + A +
Sbjct: 650 LCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP---LVSGSPLDPCDVHLQAAS 706
Query: 1738 WN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796
++ + C++L F+ C + P F C C + LC +L YA LC +
Sbjct: 707 YSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRH 762
Query: 1797 GQAPAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP-------KALPCAESC 1848
G +R R C + C YSPC +PC TC + +P C C E C
Sbjct: 763 GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC 822
Query: 1849 ECQKGHILSGTS--CVPLGQCGCTDPAGSYHP 1878
C L + CVP QC C Y P
Sbjct: 823 ACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP 854
Score = 179 bits (454), Expect = 3e-44
Identities = 144/476 (30%), Positives = 196/476 (41%), Gaps = 63/476 (13%)
Query: 1032 GTTTTSRSSTERCPPNA-RYESC--ACPASCKSPRPSCGP---LCREGCVCNPGFLFSDN 1085
G T R T C A Y C CPASC PR SC C +GC C G +F D
Sbjct: 407 GWRTQLRQCTVHCKEKAFTYNECIACCPASCH-PRASCVDSEIACVDGCYCPNGLIFEDG 465
Query: 1086 HCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY 1145
C+ + C C ++ Y PG+ E C C +G++
Sbjct: 466 GCVAPAECPCEFHGTLYPPGSV-----VKEDCN------------------TCTCTSGKW 502
Query: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG- 1204
C A C V GD H+ TFDGR + F C YILA+ + T F VT +N G
Sbjct: 503 ECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGT---FTVTLQNAPCGL 559
Query: 1205 -QEGVSCLSKVYVTL---PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL-GASGRFVEL 1259
Q+G +C+ V V L P VTL + L+ Q +P + S F+ +
Sbjct: 560 NQDG-ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRV 618
Query: 1260 QTEFGLRVRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGN 1318
+T G+RV +D + +LY+ V + GLCG ++GN+ +D L G P + GN
Sbjct: 619 RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 678
Query: 1319 SWQTDQDEDQECQKYQVVNSP--SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAAS 1376
SW+T C V SP CD LQ++ C L T F C +
Sbjct: 679 SWKT----LSACSPL-VSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVP 731
Query: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436
+F+ C D C + Q LC ++ C+ G V C ++C + +YS C
Sbjct: 732 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789
Query: 1437 KPCPDTCHSGFSGMFCS---------DRCVEACECNPGFVLSGLE--CIPRSQCGC 1481
PC TC S C D CVE C C P L C+PR+QC C
Sbjct: 790 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 845
Score = 164 bits (414), Expect = 1e-39
Identities = 201/850 (23%), Positives = 306/850 (36%), Gaps = 170/850 (20%)
Query: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
+C+ G+ H +FDG + + + LV P F I H + G+ +
Sbjct: 150 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS--FSIQV-HNDPQCGSSPYTCS 206
Query: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049
+ + + V +V LP + + ++ + Y IV + + +DG
Sbjct: 207 RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHV--MGSARLQQLAGYVIVRHQSAFTLAWDG 264
Query: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID----P 2105
+ I++ G G+CGN N + +D+L+ S ++ + EFV+SW+++ + P
Sbjct: 265 ASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP 324
Query: 2106 SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 2165
+ SL P Q+NP ++ E+CEA LR P A C + + PF
Sbjct: 325 TTSSL-----PRPPCLQQNPG------TMQGVYEQCEALLRPPFDA-CHAYVSPLPFTAS 372
Query: 2166 CANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYS-SYTNCLPS 2223
C + LC+ G C+AL + C G WR C + C + +Y C+
Sbjct: 373 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432
Query: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSW 2283
C SC C +++ AC +GC C G + + CV ++C C + HG P G S
Sbjct: 433 CPASCHPR-ASCVDSEI--ACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPG-SV 487
Query: 2284 VSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFD 2343
V C C CT G +C CP+ +CSV GD + TFD
Sbjct: 488 VKEDCNT-CTCTSGKWECSTAVCPA---------------------ECSVTGDIHFTTFD 525
Query: 2344 GFSYRLQGRMTYVLIK---------TVDVLPEGV--EPLLVEGRNKM--DPPRSSIFLQE 2390
G Y Y+L K T+ P G+ + V+ + + PR + L
Sbjct: 526 GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTL-- 583
Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPY-----------------RPNEHLRVTL--WG 2431
QAG L+ + K+ PY R N +RV G
Sbjct: 584 -----------TQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 632
Query: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491
RLYL D V GLCG ++ N ++D + P G
Sbjct: 633 LRLYLQVDQRWVED------------------TVGLCGTFNGNTQDDFLSPVGVPESTPQ 674
Query: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVL 2550
FGNSW+ + A L +G + C Q AS S QAC VL
Sbjct: 675 LFGNSWKTLS-------------------ACSPLVSGSPLDPCDVHLQAASYSVQACSVL 715
Query: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYD 2610
FA C ++P P+ E C D C P C L+ + R H
Sbjct: 716 TGEM--FAPCSAFLSPVPYFEQCRRDACRCGQP-----CLCATLAHYAHLCRRH------ 762
Query: 2611 TLPSILCQPGRPRGLRGPLRGRLRQHPRLC-LQWHPEPPLADCGCTSNGIY------YQL 2663
GL R RL C P +A CG T +
Sbjct: 763 -------------GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDG 809
Query: 2664 GSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQC 2723
G ++C + C C L + C C+ H QG + P + + G C
Sbjct: 810 GDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC--HFQGV--DYPPGDSDIPSLGHC 865
Query: 2724 REQGATFTCE 2733
+ +C+
Sbjct: 866 HCKDGVMSCD 875
Score = 152 bits (383), Expect = 6e-36
Identities = 234/1056 (22%), Positives = 367/1056 (34%), Gaps = 235/1056 (22%)
Query: 598 PTISTEKPTIPSEKPNMPSEK-PTIPSEKPTILTEKPTIPSEKPTIPSEKP-TISTEKPT 655
PT + T+P PS+ PT E+P + E P P+ +P + P T + P
Sbjct: 1471 PTEALGNETLP------PSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1524
Query: 656 VPTEEPTTPTEETTTSMEEPVIPT--EKPSIPTEKPS---------------------IP 692
TEEP T T++++P+ T + P+ PTE P+ +
Sbjct: 1525 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVA 1584
Query: 693 TEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKSTISPEKPT 739
+ PT M + T + T+ SP P P + P + T
Sbjct: 1585 LQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTT 1644
Query: 740 TPTEKPTI-PTEKPTISP----EKPT---------TPTEKPTISPEKLTIPTEKPTIPTE 785
P T P+ +P SP PT TP IS + PT+ +
Sbjct: 1645 PPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS--AS 1702
Query: 786 KPTIP-TEKPTISTEEPTTPTE----ETTISTEKP----SIPMEKPTLPTEETTTSV--- 833
P+ P T T + + P +P E +STEK S PM P P S
Sbjct: 1703 SPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR 1762
Query: 834 --EETTISTEKLTIPMEKP---TISTE------------KPTIPTEKPTISPEKLTIPTE 876
+ TT++T +P E P ++ST + T P++ + P ++P
Sbjct: 1763 PAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLA 1822
Query: 877 KL----TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKP----TISTEKP-------- 920
K+ + T P + T + + T+P + T+SP P ++ P
Sbjct: 1823 KVGTSAPVATPGPKASVITTPLQPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPA 1880
Query: 921 -----------TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTE------ 960
T+PT +P E T S + T K I +++++PT
Sbjct: 1881 AGTAPGLLLGATLPTSG-VLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAE 1939
Query: 961 ----KPTISTEKPTIPT----------EKLTIPTEKPTIPTEKPTIPTEKLTALRPP--- 1003
+ T +T P P L +PT T P + + L P
Sbjct: 1940 GGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAE 1999
Query: 1004 -HPSPTATGLAA-----LVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPA 1057
H + LAA P S P S++ G ++TE
Sbjct: 2000 AHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEA-------------- 2045
Query: 1058 SCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHC 1117
+ +C P+ + CV + C++ + N ++HC
Sbjct: 2046 ---NTSTTCVPIAEQDCV--------RHICLEG----------------QLIRVNQSQHC 2078
Query: 1118 RCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGK 1177
P +CG + G C + C ++ D +VTFDG H +
Sbjct: 2079 ---PQGAAP---PRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKE 2132
Query: 1178 CTYILAQPCGNSTDPFFRVTAKNEEQGQEG-----VSCLSKVYVTLPESTVTLLKGRRTL 1232
YIL+Q S D V + + G CL + +T VT+ + R +
Sbjct: 2133 AIYILSQ----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKV 2188
Query: 1233 VGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRW-DGDQQLYVTVSSTYSGKLCGLC 1291
Q P + G + +G + T ++++W + V S T + GLC
Sbjct: 2189 TVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLC 2248
Query: 1292 GNYDGNSDNDHLKLDGSPAGDKEELG---NSWQTDQDEDQECQ-KYQVVNSPSCDSSLQS 1347
G DG++ ND DGS G E+ +SWQ Q +++ + + D S
Sbjct: 2249 GICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSP-- 2306
Query: 1348 SMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQ 1407
C R+V ++ F C V SF + + D Q C ++ C
Sbjct: 2307 -------CLRMV-SNRTFSACHRFVPPESFCELWIRDTKYVQ----QPCVALTVYVAMCH 2354
Query: 1408 DAGHAVKPWREPHFCPMACPPNSKYSLCAKPC--PDTCHSGFSGMFCSDRCV---EACEC 1462
H WR +CP C +S Y C C P TC G G + C E C C
Sbjct: 2355 KF-HVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVC 2413
Query: 1463 NPGFVL---SGLECIPRSQCGCLHPAGSYFKVGERW 1495
+ G +L CIP ++C C G +GE W
Sbjct: 2414 SEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2449
Score = 108 bits (269), Expect = 1e-22
Identities = 102/406 (25%), Positives = 158/406 (38%), Gaps = 63/406 (15%)
Query: 1425 ACPPNSKYSLCAKPCPD-------TCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIP 1475
ACP + C+ D TC + S R C+ C C G + G C
Sbjct: 882 ACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFL 941
Query: 1476 RSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH 1535
+C C YF G++ P C CVC+ + +C C
Sbjct: 942 PEECPCTWKGKEYFP-GDQVMSP-C-HTCVCQRGS-FQCTLHPC---------------- 981
Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
A+TCTA GD HY TFDG F+G C L + + D F V N N
Sbjct: 982 ---ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKS----TSDVSFSVIVENVN------ 1028
Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTI---RLSSNLVLLYTNF 1652
Y + F +SI++ V + P + + R+ ++ +
Sbjct: 1029 -CYSSGMICRKF-ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQE 1086
Query: 1653 GLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW--- 1709
+ + +D V V + GQL GLCGN++ ++++ P+ + + G++W
Sbjct: 1087 HITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV 1146
Query: 1710 KLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASC 1768
+ P++ +P C N + + + K C+IL++ F CH VV +++C
Sbjct: 1147 ECPDTLDPR--------DMCVLNPLREPFAKKECSILLSEV--FEICHPVVDVTWFYSNC 1196
Query: 1769 VHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812
+ CG GD C S+ AYA C Q G A WR CP C
Sbjct: 1197 LTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1242
Score = 107 bits (268), Expect = 1e-22
Identities = 100/406 (24%), Positives = 147/406 (36%), Gaps = 55/406 (13%)
Query: 1037 SRSSTERCPPNARYESCA-------------CPASCKSPRPSCGPLCREGCVCNPGFLFS 1083
SR+ CP + +C+ C + S C GC C G L
Sbjct: 876 SRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRH 935
Query: 1084 DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143
+ C C C + Y PG + SP C T VCQ +
Sbjct: 936 GDACFLPEECPCTWKGKEYFPGDQVMSP--------------------CHT-CVCQRGSF 974
Query: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203
Q HP A +TC YGD HY TFDG F F+G C L + +++D F V +N
Sbjct: 975 QCTLHPCA--STCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STSDVSFSVIVENVNC 1029
Query: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ-TE 1262
G+ C + + + S + G + V G F + +
Sbjct: 1030 YSSGMICRKFISINVGNSLIVFDDDS----GNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1085
Query: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322
+ + WD ++V + G+L GLCGN+D + N+ + + +E G+SW
Sbjct: 1086 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1145
Query: 1323 DQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCM 1382
+ D + V +P + + C L+ FE C V F+ +C+
Sbjct: 1146 VECPDTLDPRDMCVLNPLREPFAKKE------CSILLSE--VFEICHPVVDVTWFYSNCL 1197
Query: 1383 LDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
D CG G C +S C G AV WR P CP C
Sbjct: 1198 TDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 93.2 bits (230), Expect = 3e-18
Identities = 93/378 (24%), Positives = 147/378 (38%), Gaps = 69/378 (18%)
Query: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSY 1598
A C+ D ++TFDG+ Y+L S+S D V + + +++
Sbjct: 2108 ACRCSIFPDLSFVTFDGSHVALFKEAIYIL-----SQSPDEMLTVHVLDCKSANLGHLNW 2162
Query: 1599 IKAVHVTVFDLSISLLRGCKVMLN----GHRVAL------------PVWLAQGRVTIRL- 1641
C VMLN H+V + PVW R R+
Sbjct: 2163 PPF---------------CLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIE 2207
Query: 1642 -SSNLVLLYTNFGLQVRY---DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697
+ ++ ++ T +Q+++ G +VE + S G GLCG + ++ +D D
Sbjct: 2208 DTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGS 2265
Query: 1698 LAG---DSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQ 1754
+ G D +W++P SS +P SC + C +++ + FS
Sbjct: 2266 VVGGAEDPAPFLDSWQVP-SSLTSVGQTRFRPDSCATTDCSP-----CLRMVSNR-TFSA 2318
Query: 1755 CHQVVPPQSSFASCVHGQCGTKGDTTAL---CRSLQAYASLCAQAGQAPAWRNRTFCPMR 1811
CH+ VPP+S + DT + C +L Y ++C + WR +CP
Sbjct: 2319 CHRFVPPESFCELWIR-------DTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL 2371
Query: 1812 CPPGSSYSPCSSPC--PDTC-SSINNPRDCPKALPCAESCECQKGHIL---SGTSCVPLG 1865
C S+Y C + C P TC I P D E C C +G IL C+P
Sbjct: 2372 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2431
Query: 1866 QCGCTDPAGSYHPVGERW 1883
+C CTD G +GE W
Sbjct: 2432 KCACTDSMGVPRALGETW 2449
Score = 80.5 bits (197), Expect = 2e-14
Identities = 107/485 (22%), Positives = 175/485 (36%), Gaps = 60/485 (12%)
Query: 569 KPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM-PSEKPTIPSEKPT 627
+P V + ++ E + PT E+P +S E P P+ +P + P+ T P
Sbjct: 1465 EPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1524
Query: 628 ILTEKPTIP--SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685
TE+P + + T+ +++ P PTE P ++ T S+ E S+P
Sbjct: 1525 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPA--SKGVTASLLAIPHTPESSSLP 1582
Query: 686 TEKPSIPTEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKST 732
+ + PT M + T + T+ SP P P +
Sbjct: 1583 -----VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHG 1637
Query: 733 ISPEKPTTPTEKPTI-PTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPT 791
P + T P T P+ +P S P + PT S + T T + +P
Sbjct: 1638 SLPVRTTPPQPSLTASPSSRPVAS---PGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQ 1694
Query: 792 EKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPT 851
S P+TP + E+ +P T E +STEK +P
Sbjct: 1695 PTQAQSASSPSTPLTVAGTAAEQ---------VPVSPLATRSLEIVLSTEKGEAGHSQPM 1745
Query: 852 ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911
S P P P+ P P + T+ T P +P E T + L+ T+ +P
Sbjct: 1746 GSPASPQ-PHPLPSAPPR----PAQHTTMATRSPALPPE--TPAAASLSTATDGLAATPF 1798
Query: 912 KPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTI 971
ST + + P +T++ K + T P +P P S +
Sbjct: 1799 MSLESTRPSQLLSGLP----PDTSLPLAK--VGTSAPVATP--------GPKASVITTPL 1844
Query: 972 PTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA-ALVMSPHAPSTPMTSVI 1030
+ T+P + T+ P P A P H +P A G A L++ P++ + V
Sbjct: 1845 QPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVA 1902
Query: 1031 LGTTT 1035
GT +
Sbjct: 1903 EGTAS 1907
Score = 76.6 bits (187), Expect = 3e-13
Identities = 87/428 (20%), Positives = 153/428 (35%), Gaps = 88/428 (20%)
Query: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTSCV 1862
CP G + CS D ++ R C + L PC C C +G + G +C
Sbjct: 883 CPAGQVFVNCSDLHTDL--ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 940
Query: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922
+C CT Y P + +TC C + FQ T P
Sbjct: 941 LPEECPCTWKGKEYFPGDQVMSPCHTCV----CQRGS----FQCTLHP------------ 980
Query: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982
C ++ C G+ HY +FDG AC + LVK
Sbjct: 981 CAST----CTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV------------------ 1018
Query: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042
+F + ++ Y + + +K + + + + S P + ++G
Sbjct: 1019 --SFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1076
Query: 2043 -----------VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSD 2091
+ + +D + ++ + G++ G+CGNF+ + +E+ P + +
Sbjct: 1077 FFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNP 1136
Query: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPV 2149
EF +SW + C L +P C LR A+++C + L + V
Sbjct: 1137 QEFGSSWAAVE----CPDTL------------DPRDMCVLNPLREPFAKKEC-SILLSEV 1179
Query: 2150 WAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2207
+ C +D+T F +C C GG + C ++ A+ C G+ WR C
Sbjct: 1180 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLC 1238
Query: 2208 PLECPAYS 2215
P +C ++
Sbjct: 1239 PYDCDFFN 1246
Score = 76.3 bits (186), Expect = 4e-13
Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 35/322 (10%)
Query: 1999 QVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF-DGNHLLEIEI 2057
QVT+ + +R + Q P +S+ G ++ + ++ +Q+++ + L+ +E
Sbjct: 2178 QVTIDRFNRKVTVDLQPVWPPVSRY-GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEA 2236
Query: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEV---ANSDSEFVNSWKDKDIDPSCQSLLVDE 2114
T + G+CG + + ++L + V A + F++SW+ PS + +
Sbjct: 2237 SKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQT 2292
Query: 2115 QQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFG 2174
+ P C R C + P + C I T ++
Sbjct: 2293 RFRPDSCATTDCSPCLRMVSNRTFSACHRFV--PPESFCELWIRDTKYV----------- 2339
Query: 2175 GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR 2234
Q C AL + A C + WR S +CP C + S+Y C+ +C P DG
Sbjct: 2340 ---QQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG- 2394
Query: 2235 CEGAKVPSAC---AEGCICQPGYVLSEDK---CVPRSQCGCKDAHGGSIPLGKSWVS--S 2286
G P C EGC+C G +L C+P ++C C D+ G LG++W S S
Sbjct: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454
Query: 2287 GCTEKCVCTGGAIQCGDFRCPS 2308
GC + I D CPS
Sbjct: 2455 GCCQHQCQAPDTIVPVDLGCPS 2476
Score = 75.1 bits (183), Expect = 9e-13
Identities = 93/442 (21%), Positives = 152/442 (34%), Gaps = 86/442 (19%)
Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
+G CQ+ N ++ C +G TFDG Y L G+ +Y L+ + PEG
Sbjct: 133 TGPRCQMVY-----NAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHE--PEG 185
Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRV 2427
+ ++ N S ++ + + ++ E+ ++ +P+
Sbjct: 186 -QSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ 244
Query: 2428 TLWGQRLYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGA 2485
L G Y++ + +++ G I + G GLCGN + + K+D++ SG
Sbjct: 245 QLAG---YVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGK 301
Query: 2486 LTQNLNTFGNSWEVKTED-----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLA 2540
LT ++ F +SW+ + + PR P ++ G G+
Sbjct: 302 LTDDVVEFVHSWQEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGV--------------- 345
Query: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVS 2600
+ C L P PF ACH V+P PF C DLC + C+ L+ +
Sbjct: 346 ---YEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMG---DVATWCRALAEYA-- 395
Query: 2601 SRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIY 2660
Q GRP L+G W + C
Sbjct: 396 -------------RACAQAGRP--LQG---------------WRTQLRQCTVHCKEKAFT 425
Query: 2661 YQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQND 2720
Y + C R +C S I + C G + G GC + C PC+
Sbjct: 426 YNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG----GCVAPAEC---PCEFH 478
Query: 2721 GQCREQGATF-----TCECEVG 2737
G G+ TC C G
Sbjct: 479 GTLYPPGSVVKEDCNTCTCTSG 500
Score = 74.3 bits (181), Expect = 2e-12
Identities = 108/465 (23%), Positives = 172/465 (36%), Gaps = 95/465 (20%)
Query: 654 PTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTIS 713
P PT + + +E+ V P +PTE T P+ + PT S
Sbjct: 1442 PVCPTPQVLDEVTQRCVYLEDCVEPAVW--VPTEALGNETLPPSQGL---------PTPS 1490
Query: 714 PEKPTIPTEKPTIPTEKSTISPEKP-TTPTEKPTIPTEKPTISP---------------- 756
E+P + E P PT + ++P P TT P TE+P +SP
Sbjct: 1491 DEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTAS 1550
Query: 757 EKPTTPTEKPT---ISPEKLTIP--TEKPTIPTEKPTIPTEKPTISTEEPTTPT------ 805
+ P PTE P ++ L IP E ++P T PT E T T
Sbjct: 1551 QLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQT-PTPGMVSGAMETTRVTVIFAGS 1609
Query: 806 EETTISTEKPSIPMEKPTLPTEETT----------TSVEETTISTEKLTIPMEKPTISTE 855
T+S+ P P + L T+ T T+ + +++ + P+ P +
Sbjct: 1610 PNITVSSRSP--PAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISR 1667
Query: 856 KPTIP-TEKPTISP-----------------EKLTIPTEKLTIP-TEKPTIPIEETTIST 896
PT + K ++P + + P+ LT+ T +P+ +
Sbjct: 1668 SPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRS 1727
Query: 897 EKLTIPTEKPTISPEKPTISTEKP---TIPTEKPTIPTEETTISTEKLTIPTEKPTISPE 953
++ + TEK +P S P +P+ P P + TT++T +P E P +
Sbjct: 1728 LEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR-PAQHTTMATRSPALPPETPAAA-- 1784
Query: 954 KLTIPTE----KPTISTEKPTIPTEKLTIPTEKPTIPTEK------PTIPTEKLTALRPP 1003
L+ T+ P +S E T P++ L+ ++P K P K + + P
Sbjct: 1785 SLSTATDGLAATPFMSLES-TRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTP 1843
Query: 1004 HPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNA 1048
P AT L A +SP P TP T + T PP A
Sbjct: 1844 -LQPQATTLPAQTLSPVLPFTP------AAMTQAHPPTHIAPPAA 1881
Score = 49.7 bits (117), Expect = 4e-05
Identities = 119/546 (21%), Positives = 192/546 (35%), Gaps = 107/546 (19%)
Query: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284
+P+ ++G E + C P ++E CV C + + +
Sbjct: 2026 APALSIVEGLAEALATTTEANTSTTCVP---IAEQDCVRHI---CLEGQLIRVNQSQHCP 2079
Query: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344
+C G A++ G RC C +CS++ D ++TFDG
Sbjct: 2080 QGAAPPRCGILGLAVRVGGDRCCPLWECAC---------------RCSIFPDLSFVTFDG 2124
Query: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMD---PPRSSIFLQEVITTVYGYKVQ 2401
L Y+L ++ D + V L + N PP + L T ++V
Sbjct: 2125 SHVALFKEAIYILSQSPDEMLT-VHVLDCKSANLGHLNWPPFCLVMLN---MTHLAHQVT 2180
Query: 2402 LQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI---SLPS 2458
+ V + + P R+ G ++T ++ + + +I S S
Sbjct: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240
Query: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALT---QNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
+G GLCG D + ND+ L G++ ++ F +SW+V P+
Sbjct: 2241 KAQG--HGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------------PSS 2285
Query: 2516 EEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
G ++CSP ++ SN T F+ACH+ V PE F E +
Sbjct: 2286 LTSVGQTRFRPDSCATTDCSPCLRMVSNRT------------FSACHRFVPPESFCELWI 2333
Query: 2575 LDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPS---------ILCQPGR--PR 2623
D Q P + + V + S+ L S C+P +
Sbjct: 2334 RDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQD 2393
Query: 2624 GLRGPL---------------RGRL--RQHPRLCLQWHPEPPLADCGCT-SNGIYYQLG- 2664
G+ GPL G + R+H LC+ P A C CT S G+ LG
Sbjct: 2394 GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCI------PEAKCACTDSMGVPRALGE 2447
Query: 2665 --SSFLTEDCSQRCTCASSRI---LLC---EPFSC-RAGEVCTLGNHTQGCFPESPCLQN 2715
+S L+ C +C + + L C P SC R GEV L C + C+ N
Sbjct: 2448 TWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2507
Query: 2716 PCQNDG 2721
+G
Sbjct: 2508 QTLCEG 2513
Score = 32.7 bits (73), Expect = 5.2
Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 19/95 (20%)
Query: 1044 CPPNARYESCACPA--SCK---SPRPSCG---------PLCREGCVCNPGFLFSDNH--C 1087
C + Y C P +C+ SP +CG C EGC C P C
Sbjct: 779 CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 837
Query: 1088 IQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPG 1122
+ + C+C + Y PG HC C G
Sbjct: 838 VPRNQCSCHFQGVDYPPGDS--DIPSLGHCHCKDG 870
>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 241 bits (614), Expect = 1e-62
Identities = 285/1239 (23%), Positives = 454/1239 (36%), Gaps = 248/1239 (20%)
Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI- 1512
+R + +C P ++ S C +C +HPA C C N
Sbjct: 25 ERRLHRAKCAPSYLFS---CFNGGEC--VHPA-----------------FCDCRRFNATG 62
Query: 1513 -RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRP 1571
RCQ +Y + + C A G H TFDG ++ G +Y L
Sbjct: 63 PRCQM--------------VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 108
Query: 1572 CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT-VFDLSISLLRGCKVMLNGHRVALPV 1630
Q F + N+ + G + +AV + V + I L + +V G RV LP
Sbjct: 109 HEPEGQS--FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK--EVTHGGMRVQLPH 164
Query: 1631 WLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
+ R ++ + V++ + +DG+ V + + G GLCGN N + DD
Sbjct: 165 VMGSAR--LQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDD 222
Query: 1691 NLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG--KPSSCQEN--SMADAWNKNCAILI 1746
+ KL D ++ +W+ ++P +P Q+N +M + + C L+
Sbjct: 223 LVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ-CEALL 281
Query: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNR 1805
P PF CH V P ASC C + GD CR+L YA CAQAG+ WR +
Sbjct: 282 RP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 339
Query: 1806 TF-CPMRCPPGS-SYSPCSSPCPDTCSSINNPR-DCPKA-LPCAESCECQKGHILSGTSC 1861
C + C + +Y+ C + CP +C +PR C + + C + C C G I C
Sbjct: 340 LRQCTVHCKEKAFTYNECIACCPASC----HPRASCVDSEIACVDGCYCPNGLIFEDGGC 395
Query: 1862 VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLL 1921
V +C C + G+ +P G + C CTC+ C + C
Sbjct: 396 VAPAECPC-EFHGTLYPPGS--VVKEDCNT-CTCT-SGKWECSTAVCPAE---------- 440
Query: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEG 1981
C + G+ H+ +FDG ++ P C +L K + + F ++ ++
Sbjct: 441 ---------CSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAPCGL 487
Query: 1982 GTEAFRLHEVYIDIYD---AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038
+ + V + ++ QVTL + VL+ + +P + + SS++ V
Sbjct: 488 NQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVR 547
Query: 2039 IKIGVQVKFDGNHL-LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
+GV+V +D L L +++ + G+CG FN +D+ + P ++ F NS
Sbjct: 548 TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 607
Query: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAA--LRAPVWAQCAS 2155
WK +C L+ P + L+ A +A L ++A C++
Sbjct: 608 WKTLS---ACSPLVSGSPLDPCD-----------VHLQAASYSVQACSVLTGEMFAPCSA 653
Query: 2156 RIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
+ P+ C C G LC L + C+ GL C L C A
Sbjct: 654 FLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK 711
Query: 2216 SYTNCLPSCSPSCWDL--------DGRCEGAKVPSACAEGCICQPGYVLSE--DKCVPRS 2265
Y+ C+ C +C DL DG + ++ C EGC C P L D CVPR+
Sbjct: 712 EYSPCVAPCGRTCQDLASPEACGVDGGDDLSR--DECVEGCACPPDTYLDTQADLCVPRN 769
Query: 2266 QCG----------------------CKD--------AHGGSIPLGKSWVSSG-------- 2287
QC CKD A + P G+ +V+
Sbjct: 770 QCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLEL 829
Query: 2288 --------------------CTEKCVCTGGAIQCGDF-----RCP--------------- 2307
C C C G ++ GD CP
Sbjct: 830 SRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM 889
Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
S H + S + + C+ YGD Y TFDG + G L+K+ +
Sbjct: 890 SPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFS 949
Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL-- 2425
V +VE N S + ++ I+ + G L+V + P P L
Sbjct: 950 V---IVENVNCYS---SGMICRKFIS--------INVGNSLIVFDDDSGNP-SPESFLDD 994
Query: 2426 --RVTLWGQRLYLVTDF---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMM 2480
V W + + F + + + R + ++G ++GLCGN+D N+M
Sbjct: 995 KQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1054
Query: 2481 LPSGALTQNLNTFGNSW-EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQL 2539
P N FG+SW V+ D L PR + LR ECS
Sbjct: 1055 TPENLELTNPQEFGSSWAAVECPDTL--DPRDMCVLNP-------LREPFAKKECS---- 1101
Query: 2540 ASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLC 2578
+L++ F CH V F +C+ D C
Sbjct: 1102 --------ILLSE---VFEICHPVVDVTWFYSNCLTDTC 1129
Score = 230 bits (586), Expect = 2e-59
Identities = 201/752 (26%), Positives = 299/752 (39%), Gaps = 77/752 (10%)
Query: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILA---QPCGNSTDPFFRVTAKNEEQ-GQEGVSCL 1211
C +G H TFDG ++ GK +Y L +P G S F + N+ Q G +C
Sbjct: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS----FSIQVHNDPQCGSSPYTCS 134
Query: 1212 SKVYVT-LPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWD 1270
V + + E + L K GG +V LP + +G +V ++ + + WD
Sbjct: 135 RAVSLFFVGEQEIHLAK--EVTHGGMRVQLPHVMGSARLQQLAG-YVIVRHQSAFTLAWD 191
Query: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330
G +Y+ +S G GLCGN + + +D + G D E +SWQ
Sbjct: 192 GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 251
Query: 1331 QKYQVVNSPSCDSSLQSSMSGP-GFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
+ P C +M G C L+ PF+ C +V F SC D+C
Sbjct: 252 PTTSSLPRPPCLQQNPGTMQGVYEQCEALL--RPPFDACHAYVSPLPFTASCTSDLCQSM 309
Query: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWR-EPHFCPMACPPNS-KYSLCAKPCPDTCHSGF 1447
G C ++ C AG ++ WR + C + C + Y+ C CP +CH
Sbjct: 310 GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRA 369
Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVGERWYKPGCKE 1502
S + CV+ C C G + C+ ++C C L+P GS K C
Sbjct: 370 SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV-------VKEDC-N 421
Query: 1503 LCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562
C C S W C A A C+ +GD H+ TFDG + F
Sbjct: 422 TCTCTSGK------WECST--------------AVCPAECSVTGDIHFTTFDGRRYTFPA 461
Query: 1563 TCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFD---LSISLLRGCKV 1619
TC Y+L + SRS + F V+ N G + + +++V V + ++L + V
Sbjct: 462 TCQYILAK---SRSSGT-FTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDV 517
Query: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHL-VEVTVPSSYGGQLCG 1678
+L +P + RLSS + + TN G++V YD L + + V + G
Sbjct: 518 LLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVG 577
Query: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP-SSCQENSMADA 1737
LCG +N N+ DD L P G +WK + P LV G P C + A +
Sbjct: 578 LCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP---LVSGSPLDPCDVHLQAAS 634
Query: 1738 WN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796
++ + C++L F+ C + P F C C + LC +L YA LC +
Sbjct: 635 YSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRH 690
Query: 1797 GQAPAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP-------KALPCAESC 1848
G +R R C + C YSPC +PC TC + +P C C E C
Sbjct: 691 GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC 750
Query: 1849 ECQKGHILSGTS--CVPLGQCGCTDPAGSYHP 1878
C L + CVP QC C Y P
Sbjct: 751 ACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP 782
Score = 179 bits (454), Expect = 3e-44
Identities = 144/476 (30%), Positives = 196/476 (41%), Gaps = 63/476 (13%)
Query: 1032 GTTTTSRSSTERCPPNA-RYESC--ACPASCKSPRPSCGP---LCREGCVCNPGFLFSDN 1085
G T R T C A Y C CPASC PR SC C +GC C G +F D
Sbjct: 335 GWRTQLRQCTVHCKEKAFTYNECIACCPASCH-PRASCVDSEIACVDGCYCPNGLIFEDG 393
Query: 1086 HCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY 1145
C+ + C C ++ Y PG+ E C C +G++
Sbjct: 394 GCVAPAECPCEFHGTLYPPGSV-----VKEDCN------------------TCTCTSGKW 430
Query: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG- 1204
C A C V GD H+ TFDGR + F C YILA+ + T F VT +N G
Sbjct: 431 ECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGT---FTVTLQNAPCGL 487
Query: 1205 -QEGVSCLSKVYVTL---PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL-GASGRFVEL 1259
Q+G +C+ V V L P VTL + L+ Q +P + S F+ +
Sbjct: 488 NQDG-ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRV 546
Query: 1260 QTEFGLRVRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGN 1318
+T G+RV +D + +LY+ V + GLCG ++GN+ +D L G P + GN
Sbjct: 547 RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 606
Query: 1319 SWQTDQDEDQECQKYQVVNSP--SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAAS 1376
SW+T C V SP CD LQ++ C L T F C +
Sbjct: 607 SWKT----LSACSPL-VSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVP 659
Query: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436
+F+ C D C + Q LC ++ C+ G V C ++C + +YS C
Sbjct: 660 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
Query: 1437 KPCPDTCHSGFSGMFCS---------DRCVEACECNPGFVLSGLE--CIPRSQCGC 1481
PC TC S C D CVE C C P L C+PR+QC C
Sbjct: 718 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 773
Score = 164 bits (414), Expect = 1e-39
Identities = 201/850 (23%), Positives = 306/850 (36%), Gaps = 170/850 (20%)
Query: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
+C+ G+ H +FDG + + + LV P F I H + G+ +
Sbjct: 78 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS--FSIQV-HNDPQCGSSPYTCS 134
Query: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049
+ + + V +V LP + + ++ + Y IV + + +DG
Sbjct: 135 RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHV--MGSARLQQLAGYVIVRHQSAFTLAWDG 192
Query: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID----P 2105
+ I++ G G+CGN N + +D+L+ S ++ + EFV+SW+++ + P
Sbjct: 193 ASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP 252
Query: 2106 SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 2165
+ SL P Q+NP ++ E+CEA LR P A C + + PF
Sbjct: 253 TTSSL-----PRPPCLQQNPG------TMQGVYEQCEALLRPPFDA-CHAYVSPLPFTAS 300
Query: 2166 CANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYS-SYTNCLPS 2223
C + LC+ G C+AL + C G WR C + C + +Y C+
Sbjct: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
Query: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSW 2283
C SC C +++ AC +GC C G + + CV ++C C + HG P G S
Sbjct: 361 CPASCHPR-ASCVDSEI--ACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPG-SV 415
Query: 2284 VSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFD 2343
V C C CT G +C CP+ +CSV GD + TFD
Sbjct: 416 VKEDCNT-CTCTSGKWECSTAVCPA---------------------ECSVTGDIHFTTFD 453
Query: 2344 GFSYRLQGRMTYVLIK---------TVDVLPEGV--EPLLVEGRNKM--DPPRSSIFLQE 2390
G Y Y+L K T+ P G+ + V+ + + PR + L
Sbjct: 454 GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTL-- 511
Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPY-----------------RPNEHLRVTL--WG 2431
QAG L+ + K+ PY R N +RV G
Sbjct: 512 -----------TQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560
Query: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491
RLYL D V GLCG ++ N ++D + P G
Sbjct: 561 LRLYLQVDQRWVED------------------TVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
Query: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVL 2550
FGNSW+ + A L +G + C Q AS S QAC VL
Sbjct: 603 LFGNSWKTLS-------------------ACSPLVSGSPLDPCDVHLQAASYSVQACSVL 643
Query: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYD 2610
FA C ++P P+ E C D C P C L+ + R H
Sbjct: 644 TGEM--FAPCSAFLSPVPYFEQCRRDACRCGQP-----CLCATLAHYAHLCRRH------ 690
Query: 2611 TLPSILCQPGRPRGLRGPLRGRLRQHPRLC-LQWHPEPPLADCGCTSNGIY------YQL 2663
GL R RL C P +A CG T +
Sbjct: 691 -------------GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDG 737
Query: 2664 GSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQC 2723
G ++C + C C L + C C+ H QG + P + + G C
Sbjct: 738 GDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC--HFQGV--DYPPGDSDIPSLGHC 793
Query: 2724 REQGATFTCE 2733
+ +C+
Sbjct: 794 HCKDGVMSCD 803
Score = 150 bits (380), Expect = 1e-35
Identities = 230/1054 (21%), Positives = 366/1054 (34%), Gaps = 231/1054 (21%)
Query: 598 PTISTEKPTIPSEKPNMPSEK-PTIPSEKPTILTEKPTIPSEKPTIPSEKP-TISTEKPT 655
PT + T+P PS+ PT E+P + E P P+ +P + P T + P
Sbjct: 1399 PTEALGNETLP------PSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1452
Query: 656 VPTEEPTTPTEETTTSMEEPVIPT--EKPSIPTEKPS---------------------IP 692
TEEP T T++++P+ T + P+ PTE P+ +
Sbjct: 1453 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVA 1512
Query: 693 TEKPTISMEETIISTEKPTI-------------SPEKPTIP--TEKPTI------PTEKS 731
+ PT M + T + T+ SP P P T+ T+ P +
Sbjct: 1513 LQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTT 1572
Query: 732 TISPEKPTTPTEKPTIP----TEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKP 787
+ P +P+ +P + PT S T T + +P P
Sbjct: 1573 PLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSP 1632
Query: 788 TIP-TEKPTISTEEPTTPTE----ETTISTEKP----SIPMEKPTLPTEETTTSV----- 833
+ P T T + + P +P E +STEK S PM P P S
Sbjct: 1633 STPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPA 1692
Query: 834 EETTISTEKLTIPMEKP---TISTE------------KPTIPTEKPTISPEKLTIPTEKL 878
+ TT++T +P E P ++ST + T P++ + P ++P K+
Sbjct: 1693 QHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKV 1752
Query: 879 ----TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKP----TISTEKP---------- 920
+ T P + T + + T+P + T+SP P ++ P
Sbjct: 1753 GTSAPVATPGPKASVITTPLQPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAG 1810
Query: 921 ---------TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTE-------- 960
T+PT +P E T S + T K I +++++PT
Sbjct: 1811 TAPGLLLGATLPTSG-VLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGG 1869
Query: 961 --KPTISTEKPTIPT----------EKLTIPTEKPTIPTEKPTIPTEKLTALRPP----H 1004
+ T +T P P L +PT T P + + L P H
Sbjct: 1870 PTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAH 1929
Query: 1005 PSPTATGLAA-----LVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASC 1059
+ LAA P S P S++ G ++TE
Sbjct: 1930 GTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEA---------------- 1973
Query: 1060 KSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRC 1119
+ +C P+ + CV + C++ + N ++HC
Sbjct: 1974 -NTSTTCVPIAEQDCV--------RHICLEG----------------QLIRVNQSQHC-- 2006
Query: 1120 WPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCT 1179
P +CG + G C + C ++ D +VTFDG H +
Sbjct: 2007 -PQGAAP---PRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAI 2062
Query: 1180 YILAQPCGNSTDPFFRVTAKNEEQGQEG-----VSCLSKVYVTLPESTVTLLKGRRTLVG 1234
YIL+Q S D V + + G CL + +T VT+ + R +
Sbjct: 2063 YILSQ----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKVTV 2118
Query: 1235 GQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRW-DGDQQLYVTVSSTYSGKLCGLCGN 1293
Q P + G + +G + T ++++W + V S T + GLCG
Sbjct: 2119 DLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGI 2178
Query: 1294 YDGNSDNDHLKLDGSPAGDKEELG---NSWQTDQDEDQECQ-KYQVVNSPSCDSSLQSSM 1349
DG++ ND DGS G E+ +SWQ Q +++ + + D S
Sbjct: 2179 CDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSP---- 2234
Query: 1350 SGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDA 1409
C R+V ++ F C V SF + + D Q C ++ C
Sbjct: 2235 -----CLRMV-SNRTFSACHRFVPPESFCELWIRDTKYVQ----QPCVALTVYVAMCHKF 2284
Query: 1410 GHAVKPWREPHFCPMACPPNSKYSLCAKPC--PDTCHSGFSGMFCSDRCV---EACECNP 1464
H WR +CP C +S Y C C P TC G G + C E C C+
Sbjct: 2285 -HVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSE 2343
Query: 1465 GFVL---SGLECIPRSQCGCLHPAGSYFKVGERW 1495
G +L CIP ++C C G +GE W
Sbjct: 2344 GTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2377
Score = 108 bits (269), Expect = 1e-22
Identities = 102/406 (25%), Positives = 158/406 (38%), Gaps = 63/406 (15%)
Query: 1425 ACPPNSKYSLCAKPCPD-------TCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIP 1475
ACP + C+ D TC + S R C+ C C G + G C
Sbjct: 810 ACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFL 869
Query: 1476 RSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH 1535
+C C YF G++ P C CVC+ + +C C
Sbjct: 870 PEECPCTWKGKEYFP-GDQVMSP-C-HTCVCQRGS-FQCTLHPC---------------- 909
Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
A+TCTA GD HY TFDG F+G C L + + D F V N N
Sbjct: 910 ---ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKS----TSDVSFSVIVENVN------ 956
Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTI---RLSSNLVLLYTNF 1652
Y + F +SI++ V + P + + R+ ++ +
Sbjct: 957 -CYSSGMICRKF-ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQE 1014
Query: 1653 GLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW--- 1709
+ + +D V V + GQL GLCGN++ ++++ P+ + + G++W
Sbjct: 1015 HITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV 1074
Query: 1710 KLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASC 1768
+ P++ +P C N + + + K C+IL++ F CH VV +++C
Sbjct: 1075 ECPDTLDPR--------DMCVLNPLREPFAKKECSILLSEV--FEICHPVVDVTWFYSNC 1124
Query: 1769 VHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812
+ CG GD C S+ AYA C Q G A WR CP C
Sbjct: 1125 LTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170
Score = 107 bits (268), Expect = 1e-22
Identities = 100/406 (24%), Positives = 147/406 (36%), Gaps = 55/406 (13%)
Query: 1037 SRSSTERCPPNARYESCA-------------CPASCKSPRPSCGPLCREGCVCNPGFLFS 1083
SR+ CP + +C+ C + S C GC C G L
Sbjct: 804 SRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRH 863
Query: 1084 DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143
+ C C C + Y PG + SP C T VCQ +
Sbjct: 864 GDACFLPEECPCTWKGKEYFPGDQVMSP--------------------CHT-CVCQRGSF 902
Query: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203
Q HP A +TC YGD HY TFDG F F+G C L + +++D F V +N
Sbjct: 903 QCTLHPCA--STCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STSDVSFSVIVENVNC 957
Query: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ-TE 1262
G+ C + + + S + G + V G F + +
Sbjct: 958 YSSGMICRKFISINVGNSLIVFDDDS----GNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1013
Query: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322
+ + WD ++V + G+L GLCGN+D + N+ + + +E G+SW
Sbjct: 1014 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1073
Query: 1323 DQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCM 1382
+ D + V +P + + C L+ FE C V F+ +C+
Sbjct: 1074 VECPDTLDPRDMCVLNPLREPFAKKE------CSILLSE--VFEICHPVVDVTWFYSNCL 1125
Query: 1383 LDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
D CG G C +S C G AV WR P CP C
Sbjct: 1126 TDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 93.2 bits (230), Expect = 3e-18
Identities = 93/378 (24%), Positives = 147/378 (38%), Gaps = 69/378 (18%)
Query: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSY 1598
A C+ D ++TFDG+ Y+L S+S D V + + +++
Sbjct: 2036 ACRCSIFPDLSFVTFDGSHVALFKEAIYIL-----SQSPDEMLTVHVLDCKSANLGHLNW 2090
Query: 1599 IKAVHVTVFDLSISLLRGCKVMLN----GHRVAL------------PVWLAQGRVTIRL- 1641
C VMLN H+V + PVW R R+
Sbjct: 2091 PPF---------------CLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIE 2135
Query: 1642 -SSNLVLLYTNFGLQVRY---DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697
+ ++ ++ T +Q+++ G +VE + S G GLCG + ++ +D D
Sbjct: 2136 DTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGS 2193
Query: 1698 LAG---DSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQ 1754
+ G D +W++P SS +P SC + C +++ + FS
Sbjct: 2194 VVGGAEDPAPFLDSWQVP-SSLTSVGQTRFRPDSCATTDCSP-----CLRMVSNR-TFSA 2246
Query: 1755 CHQVVPPQSSFASCVHGQCGTKGDTTAL---CRSLQAYASLCAQAGQAPAWRNRTFCPMR 1811
CH+ VPP+S + DT + C +L Y ++C + WR +CP
Sbjct: 2247 CHRFVPPESFCELWIR-------DTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL 2299
Query: 1812 CPPGSSYSPCSSPC--PDTC-SSINNPRDCPKALPCAESCECQKGHIL---SGTSCVPLG 1865
C S+Y C + C P TC I P D E C C +G IL C+P
Sbjct: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2359
Query: 1866 QCGCTDPAGSYHPVGERW 1883
+C CTD G +GE W
Sbjct: 2360 KCACTDSMGVPRALGETW 2377
Score = 81.3 bits (199), Expect = 1e-14
Identities = 105/477 (22%), Positives = 174/477 (36%), Gaps = 44/477 (9%)
Query: 569 KPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM-PSEKPTIPSEKPT 627
+P V + ++ E + PT E+P +S E P P+ +P + P+ T P
Sbjct: 1393 EPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1452
Query: 628 ILTEKPTIP--SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685
TE+P + + T+ +++ P PTE P ++ T S+ E S+P
Sbjct: 1453 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPA--SKGVTASLLAIPHTPESSSLP 1510
Query: 686 TEKPSIPTEKPTISMEETIISTEKPT-ISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK 744
+ + PT M + T + T I P I + P + + K T
Sbjct: 1511 -----VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLM-TKAVTVRGH 1564
Query: 745 PTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTP 804
++P + P +P+ +P SP + + PT + T T P
Sbjct: 1565 GSLPVRTTPLQPSLTASPSSRPVASPGAI---SRSPTSSGSHKAVLTPAVTKVISRTGVP 1621
Query: 805 TEETTISTEKPSIPM-----EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTI 859
S PS P+ +P T E +STEK +P S P
Sbjct: 1622 QPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ- 1680
Query: 860 PTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEK 919
P P+ P P + T+ T P +P E T + L+ T+ +P ST
Sbjct: 1681 PHPLPSAPPR----PAQHTTMATRSPALPPE--TPAAASLSTATDGLAATPFMSLESTRP 1734
Query: 920 PTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIP 979
+ + P +T++ K + T P +P P S + + T+P
Sbjct: 1735 SQLLSGLP----PDTSLPLAK--VGTSAPVATP--------GPKASVITTPLQPQATTLP 1780
Query: 980 TEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA-ALVMSPHAPSTPMTSVILGTTT 1035
+ T+ P P A P H +P A G A L++ P++ + V GT +
Sbjct: 1781 AQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTAS 1835
Score = 76.6 bits (187), Expect = 3e-13
Identities = 87/428 (20%), Positives = 153/428 (35%), Gaps = 88/428 (20%)
Query: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTSCV 1862
CP G + CS D ++ R C + L PC C C +G + G +C
Sbjct: 811 CPAGQVFVNCSDLHTDL--ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 868
Query: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922
+C CT Y P + +TC C + FQ T P
Sbjct: 869 LPEECPCTWKGKEYFPGDQVMSPCHTCV----CQRGS----FQCTLHP------------ 908
Query: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982
C ++ C G+ HY +FDG AC + LVK
Sbjct: 909 CAST----CTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV------------------ 946
Query: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042
+F + ++ Y + + +K + + + + S P + ++G
Sbjct: 947 --SFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1004
Query: 2043 -----------VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSD 2091
+ + +D + ++ + G++ G+CGNF+ + +E+ P + +
Sbjct: 1005 FFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNP 1064
Query: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPV 2149
EF +SW + C L +P C LR A+++C + L + V
Sbjct: 1065 QEFGSSWAAVE----CPDTL------------DPRDMCVLNPLREPFAKKEC-SILLSEV 1107
Query: 2150 WAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2207
+ C +D+T F +C C GG + C ++ A+ C G+ WR C
Sbjct: 1108 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLC 1166
Query: 2208 PLECPAYS 2215
P +C ++
Sbjct: 1167 PYDCDFFN 1174
Score = 76.3 bits (186), Expect = 4e-13
Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 35/322 (10%)
Query: 1999 QVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF-DGNHLLEIEI 2057
QVT+ + +R + Q P +S+ G ++ + ++ +Q+++ + L+ +E
Sbjct: 2106 QVTIDRFNRKVTVDLQPVWPPVSRY-GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEA 2164
Query: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEV---ANSDSEFVNSWKDKDIDPSCQSLLVDE 2114
T + G+CG + + ++L + V A + F++SW+ PS + +
Sbjct: 2165 SKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQT 2220
Query: 2115 QQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFG 2174
+ P C R C + P + C I T ++
Sbjct: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFV--PPESFCELWIRDTKYV----------- 2267
Query: 2175 GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR 2234
Q C AL + A C + WR S +CP C + S+Y C+ +C P DG
Sbjct: 2268 ---QQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG- 2322
Query: 2235 CEGAKVPSAC---AEGCICQPGYVLSEDK---CVPRSQCGCKDAHGGSIPLGKSWVS--S 2286
G P C EGC+C G +L C+P ++C C D+ G LG++W S S
Sbjct: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
Query: 2287 GCTEKCVCTGGAIQCGDFRCPS 2308
GC + I D CPS
Sbjct: 2383 GCCQHQCQAPDTIVPVDLGCPS 2404
Score = 75.9 bits (185), Expect = 5e-13
Identities = 109/470 (23%), Positives = 168/470 (35%), Gaps = 91/470 (19%)
Query: 647 PTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIS 706
P + P PT + + +E+ V P +PTE T P+ +
Sbjct: 1363 PRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAVW--VPTEALGNETLPPSQGL------ 1414
Query: 707 TEKPTISPEKPTIPTEKPTIPTEKSTISPEKP-TTPTEKPTIPTEKPTISP--------- 756
PT S E+P + E P PT + ++P P TT P TE+P +SP
Sbjct: 1415 ---PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQ 1471
Query: 757 -------EKPTTPTEKPT---ISPEKLTIP--TEKPTIPTEKPTIPTEKPTISTEEPTTP 804
+ P PTE P ++ L IP E ++P T PT E T
Sbjct: 1472 PLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQT-PTPGMVSGAMETTRV 1530
Query: 805 T------EETTISTEKPSIP----MEKPTLPTEETTTSVEETTISTEKLTIPMEKP---- 850
T T+S+ P P M K + V T + P +P
Sbjct: 1531 TVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPVASP 1590
Query: 851 -TISTEKPTIPTEKPTISP-----------------EKLTIPTEKLTIP-TEKPTIPIEE 891
IS + + K ++P + + P+ LT+ T +P+
Sbjct: 1591 GAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSP 1650
Query: 892 TTISTEKLTIPTEKPTISPEKPTISTEKP---TIPTEKPTIPTEETTISTEKLTIPTEKP 948
+ ++ + TEK +P S P +P+ P P + TT++T +P E P
Sbjct: 1651 LATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR-PAQHTTMATRSPALPPETP 1709
Query: 949 TISPEKLTIPTE----KPTISTEKPTIPTEKLTIPTEKPTIPTEK------PTIPTEKLT 998
+ L+ T+ P +S E T P++ L+ ++P K P K +
Sbjct: 1710 AAA--SLSTATDGLAATPFMSLES-TRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKAS 1766
Query: 999 ALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNA 1048
+ P P AT L A +SP P TP T + T PP A
Sbjct: 1767 VITTP-LQPQATTLPAQTLSPVLPFTP------AAMTQAHPPTHIAPPAA 1809
Score = 75.1 bits (183), Expect = 9e-13
Identities = 93/442 (21%), Positives = 152/442 (34%), Gaps = 86/442 (19%)
Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
+G CQ+ N ++ C +G TFDG Y L G+ +Y L+ + PEG
Sbjct: 61 TGPRCQMVY-----NAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHE--PEG 113
Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRV 2427
+ ++ N S ++ + + ++ E+ ++ +P+
Sbjct: 114 -QSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ 172
Query: 2428 TLWGQRLYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGA 2485
L G Y++ + +++ G I + G GLCGN + + K+D++ SG
Sbjct: 173 QLAG---YVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGK 229
Query: 2486 LTQNLNTFGNSWEVKTED-----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLA 2540
LT ++ F +SW+ + + PR P ++ G G+
Sbjct: 230 LTDDVVEFVHSWQEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGV--------------- 273
Query: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVS 2600
+ C L P PF ACH V+P PF C DLC + C+ L+ +
Sbjct: 274 ---YEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMG---DVATWCRALAEYA-- 323
Query: 2601 SRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIY 2660
Q GRP L+G W + C
Sbjct: 324 -------------RACAQAGRP--LQG---------------WRTQLRQCTVHCKEKAFT 353
Query: 2661 YQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQND 2720
Y + C R +C S I + C G + G GC + C PC+
Sbjct: 354 YNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG----GCVAPAEC---PCEFH 406
Query: 2721 GQCREQGATF-----TCECEVG 2737
G G+ TC C G
Sbjct: 407 GTLYPPGSVVKEDCNTCTCTSG 428
Score = 49.7 bits (117), Expect = 4e-05
Identities = 119/546 (21%), Positives = 192/546 (35%), Gaps = 107/546 (19%)
Query: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284
+P+ ++G E + C P ++E CV C + + +
Sbjct: 1954 APALSIVEGLAEALATTTEANTSTTCVP---IAEQDCVRHI---CLEGQLIRVNQSQHCP 2007
Query: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344
+C G A++ G RC C +CS++ D ++TFDG
Sbjct: 2008 QGAAPPRCGILGLAVRVGGDRCCPLWECAC---------------RCSIFPDLSFVTFDG 2052
Query: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMD---PPRSSIFLQEVITTVYGYKVQ 2401
L Y+L ++ D + V L + N PP + L T ++V
Sbjct: 2053 SHVALFKEAIYILSQSPDEMLT-VHVLDCKSANLGHLNWPPFCLVMLN---MTHLAHQVT 2108
Query: 2402 LQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI---SLPS 2458
+ V + + P R+ G ++T ++ + + +I S S
Sbjct: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
Query: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALT---QNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
+G GLCG D + ND+ L G++ ++ F +SW+V P+
Sbjct: 2169 KAQG--HGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------------PSS 2213
Query: 2516 EEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
G ++CSP ++ SN T F+ACH+ V PE F E +
Sbjct: 2214 LTSVGQTRFRPDSCATTDCSPCLRMVSNRT------------FSACHRFVPPESFCELWI 2261
Query: 2575 LDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPS---------ILCQPGR--PR 2623
D Q P + + V + S+ L S C+P +
Sbjct: 2262 RDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQD 2321
Query: 2624 GLRGPL---------------RGRL--RQHPRLCLQWHPEPPLADCGCT-SNGIYYQLG- 2664
G+ GPL G + R+H LC+ P A C CT S G+ LG
Sbjct: 2322 GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCI------PEAKCACTDSMGVPRALGE 2375
Query: 2665 --SSFLTEDCSQRCTCASSRI---LLC---EPFSC-RAGEVCTLGNHTQGCFPESPCLQN 2715
+S L+ C +C + + L C P SC R GEV L C + C+ N
Sbjct: 2376 TWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2435
Query: 2716 PCQNDG 2721
+G
Sbjct: 2436 QTLCEG 2441
Score = 32.7 bits (73), Expect = 5.2
Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 19/95 (20%)
Query: 1044 CPPNARYESCACPA--SCK---SPRPSCG---------PLCREGCVCNPGFLFSDNH--C 1087
C + Y C P +C+ SP +CG C EGC C P C
Sbjct: 707 CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 765
Query: 1088 IQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPG 1122
+ + C+C + Y PG HC C G
Sbjct: 766 VPRNQCSCHFQGVDYPPGDS--DIPSLGHCHCKDG 798
>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 241 bits (614), Expect = 1e-62
Identities = 285/1239 (23%), Positives = 454/1239 (36%), Gaps = 248/1239 (20%)
Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI- 1512
+R + +C P ++ S C +C +HPA C C N
Sbjct: 97 ERRLHRAKCAPSYLFS---CFNGGEC--VHPA-----------------FCDCRRFNATG 134
Query: 1513 -RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRP 1571
RCQ +Y + + C A G H TFDG ++ G +Y L
Sbjct: 135 PRCQM--------------VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 180
Query: 1572 CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT-VFDLSISLLRGCKVMLNGHRVALPV 1630
Q F + N+ + G + +AV + V + I L + +V G RV LP
Sbjct: 181 HEPEGQS--FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK--EVTHGGMRVQLPH 236
Query: 1631 WLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
+ R ++ + V++ + +DG+ V + + G GLCGN N + DD
Sbjct: 237 VMGSAR--LQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDD 294
Query: 1691 NLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG--KPSSCQEN--SMADAWNKNCAILI 1746
+ KL D ++ +W+ ++P +P Q+N +M + + C L+
Sbjct: 295 LVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ-CEALL 353
Query: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNR 1805
P PF CH V P ASC C + GD CR+L YA CAQAG+ WR +
Sbjct: 354 RP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 411
Query: 1806 TF-CPMRCPPGS-SYSPCSSPCPDTCSSINNPR-DCPKA-LPCAESCECQKGHILSGTSC 1861
C + C + +Y+ C + CP +C +PR C + + C + C C G I C
Sbjct: 412 LRQCTVHCKEKAFTYNECIACCPASC----HPRASCVDSEIACVDGCYCPNGLIFEDGGC 467
Query: 1862 VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLL 1921
V +C C + G+ +P G + C CTC+ C + C
Sbjct: 468 VAPAECPC-EFHGTLYPPGS--VVKEDCNT-CTCT-SGKWECSTAVCPAE---------- 512
Query: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEG 1981
C + G+ H+ +FDG ++ P C +L K + + F ++ ++
Sbjct: 513 ---------CSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAPCGL 559
Query: 1982 GTEAFRLHEVYIDIYD---AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038
+ + V + ++ QVTL + VL+ + +P + + SS++ V
Sbjct: 560 NQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVR 619
Query: 2039 IKIGVQVKFDGNHL-LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
+GV+V +D L L +++ + G+CG FN +D+ + P ++ F NS
Sbjct: 620 TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 679
Query: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAA--LRAPVWAQCAS 2155
WK +C L+ P + L+ A +A L ++A C++
Sbjct: 680 WKTLS---ACSPLVSGSPLDPCD-----------VHLQAASYSVQACSVLTGEMFAPCSA 725
Query: 2156 RIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
+ P+ C C G LC L + C+ GL C L C A
Sbjct: 726 FLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK 783
Query: 2216 SYTNCLPSCSPSCWDL--------DGRCEGAKVPSACAEGCICQPGYVLSE--DKCVPRS 2265
Y+ C+ C +C DL DG + ++ C EGC C P L D CVPR+
Sbjct: 784 EYSPCVAPCGRTCQDLASPEACGVDGGDDLSR--DECVEGCACPPDTYLDTQADLCVPRN 841
Query: 2266 QCG----------------------CKD--------AHGGSIPLGKSWVSSG-------- 2287
QC CKD A + P G+ +V+
Sbjct: 842 QCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLEL 901
Query: 2288 --------------------CTEKCVCTGGAIQCGDF-----RCP--------------- 2307
C C C G ++ GD CP
Sbjct: 902 SRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM 961
Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
S H + S + + C+ YGD Y TFDG + G L+K+ +
Sbjct: 962 SPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFS 1021
Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL-- 2425
V +VE N S + ++ I+ + G L+V + P P L
Sbjct: 1022 V---IVENVNCYS---SGMICRKFIS--------INVGNSLIVFDDDSGNP-SPESFLDD 1066
Query: 2426 --RVTLWGQRLYLVTDF---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMM 2480
V W + + F + + + R + ++G ++GLCGN+D N+M
Sbjct: 1067 KQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1126
Query: 2481 LPSGALTQNLNTFGNSW-EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQL 2539
P N FG+SW V+ D L PR + LR ECS
Sbjct: 1127 TPENLELTNPQEFGSSWAAVECPDTL--DPRDMCVLNP-------LREPFAKKECS---- 1173
Query: 2540 ASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLC 2578
+L++ F CH V F +C+ D C
Sbjct: 1174 --------ILLSE---VFEICHPVVDVTWFYSNCLTDTC 1201
Score = 230 bits (586), Expect = 2e-59
Identities = 201/752 (26%), Positives = 299/752 (39%), Gaps = 77/752 (10%)
Query: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILA---QPCGNSTDPFFRVTAKNEEQ-GQEGVSCL 1211
C +G H TFDG ++ GK +Y L +P G S F + N+ Q G +C
Sbjct: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS----FSIQVHNDPQCGSSPYTCS 206
Query: 1212 SKVYVT-LPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWD 1270
V + + E + L K GG +V LP + +G +V ++ + + WD
Sbjct: 207 RAVSLFFVGEQEIHLAK--EVTHGGMRVQLPHVMGSARLQQLAG-YVIVRHQSAFTLAWD 263
Query: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330
G +Y+ +S G GLCGN + + +D + G D E +SWQ
Sbjct: 264 GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 323
Query: 1331 QKYQVVNSPSCDSSLQSSMSGP-GFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
+ P C +M G C L+ PF+ C +V F SC D+C
Sbjct: 324 PTTSSLPRPPCLQQNPGTMQGVYEQCEALL--RPPFDACHAYVSPLPFTASCTSDLCQSM 381
Query: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWR-EPHFCPMACPPNS-KYSLCAKPCPDTCHSGF 1447
G C ++ C AG ++ WR + C + C + Y+ C CP +CH
Sbjct: 382 GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRA 441
Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVGERWYKPGCKE 1502
S + CV+ C C G + C+ ++C C L+P GS K C
Sbjct: 442 SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV-------VKEDC-N 493
Query: 1503 LCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562
C C S W C A A C+ +GD H+ TFDG + F
Sbjct: 494 TCTCTSGK------WECST--------------AVCPAECSVTGDIHFTTFDGRRYTFPA 533
Query: 1563 TCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFD---LSISLLRGCKV 1619
TC Y+L + SRS + F V+ N G + + +++V V + ++L + V
Sbjct: 534 TCQYILAK---SRSSGT-FTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDV 589
Query: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHL-VEVTVPSSYGGQLCG 1678
+L +P + RLSS + + TN G++V YD L + + V + G
Sbjct: 590 LLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVG 649
Query: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP-SSCQENSMADA 1737
LCG +N N+ DD L P G +WK + P LV G P C + A +
Sbjct: 650 LCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP---LVSGSPLDPCDVHLQAAS 706
Query: 1738 WN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796
++ + C++L F+ C + P F C C + LC +L YA LC +
Sbjct: 707 YSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRH 762
Query: 1797 GQAPAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP-------KALPCAESC 1848
G +R R C + C YSPC +PC TC + +P C C E C
Sbjct: 763 GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC 822
Query: 1849 ECQKGHILSGTS--CVPLGQCGCTDPAGSYHP 1878
C L + CVP QC C Y P
Sbjct: 823 ACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP 854
Score = 179 bits (454), Expect = 3e-44
Identities = 144/476 (30%), Positives = 196/476 (41%), Gaps = 63/476 (13%)
Query: 1032 GTTTTSRSSTERCPPNA-RYESC--ACPASCKSPRPSCGP---LCREGCVCNPGFLFSDN 1085
G T R T C A Y C CPASC PR SC C +GC C G +F D
Sbjct: 407 GWRTQLRQCTVHCKEKAFTYNECIACCPASCH-PRASCVDSEIACVDGCYCPNGLIFEDG 465
Query: 1086 HCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY 1145
C+ + C C ++ Y PG+ E C C +G++
Sbjct: 466 GCVAPAECPCEFHGTLYPPGSV-----VKEDCN------------------TCTCTSGKW 502
Query: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG- 1204
C A C V GD H+ TFDGR + F C YILA+ + T F VT +N G
Sbjct: 503 ECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGT---FTVTLQNAPCGL 559
Query: 1205 -QEGVSCLSKVYVTL---PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL-GASGRFVEL 1259
Q+G +C+ V V L P VTL + L+ Q +P + S F+ +
Sbjct: 560 NQDG-ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRV 618
Query: 1260 QTEFGLRVRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGN 1318
+T G+RV +D + +LY+ V + GLCG ++GN+ +D L G P + GN
Sbjct: 619 RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 678
Query: 1319 SWQTDQDEDQECQKYQVVNSP--SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAAS 1376
SW+T C V SP CD LQ++ C L T F C +
Sbjct: 679 SWKT----LSACSPL-VSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVP 731
Query: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436
+F+ C D C + Q LC ++ C+ G V C ++C + +YS C
Sbjct: 732 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789
Query: 1437 KPCPDTCHSGFSGMFCS---------DRCVEACECNPGFVLSGLE--CIPRSQCGC 1481
PC TC S C D CVE C C P L C+PR+QC C
Sbjct: 790 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 845
Score = 164 bits (414), Expect = 1e-39
Identities = 201/850 (23%), Positives = 306/850 (36%), Gaps = 170/850 (20%)
Query: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
+C+ G+ H +FDG + + + LV P F I H + G+ +
Sbjct: 150 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS--FSIQV-HNDPQCGSSPYTCS 206
Query: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049
+ + + V +V LP + + ++ + Y IV + + +DG
Sbjct: 207 RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHV--MGSARLQQLAGYVIVRHQSAFTLAWDG 264
Query: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID----P 2105
+ I++ G G+CGN N + +D+L+ S ++ + EFV+SW+++ + P
Sbjct: 265 ASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP 324
Query: 2106 SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 2165
+ SL P Q+NP ++ E+CEA LR P A C + + PF
Sbjct: 325 TTSSL-----PRPPCLQQNPG------TMQGVYEQCEALLRPPFDA-CHAYVSPLPFTAS 372
Query: 2166 CANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYS-SYTNCLPS 2223
C + LC+ G C+AL + C G WR C + C + +Y C+
Sbjct: 373 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432
Query: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSW 2283
C SC C +++ AC +GC C G + + CV ++C C + HG P G S
Sbjct: 433 CPASCHPR-ASCVDSEI--ACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPG-SV 487
Query: 2284 VSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFD 2343
V C C CT G +C CP+ +CSV GD + TFD
Sbjct: 488 VKEDCNT-CTCTSGKWECSTAVCPA---------------------ECSVTGDIHFTTFD 525
Query: 2344 GFSYRLQGRMTYVLIK---------TVDVLPEGV--EPLLVEGRNKM--DPPRSSIFLQE 2390
G Y Y+L K T+ P G+ + V+ + + PR + L
Sbjct: 526 GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTL-- 583
Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPY-----------------RPNEHLRVTL--WG 2431
QAG L+ + K+ PY R N +RV G
Sbjct: 584 -----------TQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 632
Query: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491
RLYL D V GLCG ++ N ++D + P G
Sbjct: 633 LRLYLQVDQRWVED------------------TVGLCGTFNGNTQDDFLSPVGVPESTPQ 674
Query: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVL 2550
FGNSW+ + A L +G + C Q AS S QAC VL
Sbjct: 675 LFGNSWKTLS-------------------ACSPLVSGSPLDPCDVHLQAASYSVQACSVL 715
Query: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYD 2610
FA C ++P P+ E C D C P C L+ + R H
Sbjct: 716 TGEM--FAPCSAFLSPVPYFEQCRRDACRCGQP-----CLCATLAHYAHLCRRH------ 762
Query: 2611 TLPSILCQPGRPRGLRGPLRGRLRQHPRLC-LQWHPEPPLADCGCTSNGIY------YQL 2663
GL R RL C P +A CG T +
Sbjct: 763 -------------GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDG 809
Query: 2664 GSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQC 2723
G ++C + C C L + C C+ H QG + P + + G C
Sbjct: 810 GDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC--HFQGV--DYPPGDSDIPSLGHC 865
Query: 2724 REQGATFTCE 2733
+ +C+
Sbjct: 866 HCKDGVMSCD 875
Score = 150 bits (380), Expect = 1e-35
Identities = 230/1054 (21%), Positives = 366/1054 (34%), Gaps = 231/1054 (21%)
Query: 598 PTISTEKPTIPSEKPNMPSEK-PTIPSEKPTILTEKPTIPSEKPTIPSEKP-TISTEKPT 655
PT + T+P PS+ PT E+P + E P P+ +P + P T + P
Sbjct: 1471 PTEALGNETLP------PSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1524
Query: 656 VPTEEPTTPTEETTTSMEEPVIPT--EKPSIPTEKPS---------------------IP 692
TEEP T T++++P+ T + P+ PTE P+ +
Sbjct: 1525 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVA 1584
Query: 693 TEKPTISMEETIISTEKPTI-------------SPEKPTIP--TEKPTI------PTEKS 731
+ PT M + T + T+ SP P P T+ T+ P +
Sbjct: 1585 LQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTT 1644
Query: 732 TISPEKPTTPTEKPTIP----TEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKP 787
+ P +P+ +P + PT S T T + +P P
Sbjct: 1645 PLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSP 1704
Query: 788 TIP-TEKPTISTEEPTTPTE----ETTISTEKP----SIPMEKPTLPTEETTTSV----- 833
+ P T T + + P +P E +STEK S PM P P S
Sbjct: 1705 STPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPRPA 1764
Query: 834 EETTISTEKLTIPMEKP---TISTE------------KPTIPTEKPTISPEKLTIPTEKL 878
+ TT++T +P E P ++ST + T P++ + P ++P K+
Sbjct: 1765 QHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKV 1824
Query: 879 ----TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKP----TISTEKP---------- 920
+ T P + T + + T+P + T+SP P ++ P
Sbjct: 1825 GTSAPVATPGPKASVITTPLQPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAG 1882
Query: 921 ---------TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTE-------- 960
T+PT +P E T S + T K I +++++PT
Sbjct: 1883 TAPGLLLGATLPTSG-VLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGG 1941
Query: 961 --KPTISTEKPTIPT----------EKLTIPTEKPTIPTEKPTIPTEKLTALRPP----H 1004
+ T +T P P L +PT T P + + L P H
Sbjct: 1942 PTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAH 2001
Query: 1005 PSPTATGLAA-----LVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASC 1059
+ LAA P S P S++ G ++TE
Sbjct: 2002 GTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEA---------------- 2045
Query: 1060 KSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRC 1119
+ +C P+ + CV + C++ + N ++HC
Sbjct: 2046 -NTSTTCVPIAEQDCV--------RHICLEG----------------QLIRVNQSQHC-- 2078
Query: 1120 WPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCT 1179
P +CG + G C + C ++ D +VTFDG H +
Sbjct: 2079 -PQGAAP---PRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAI 2134
Query: 1180 YILAQPCGNSTDPFFRVTAKNEEQGQEG-----VSCLSKVYVTLPESTVTLLKGRRTLVG 1234
YIL+Q S D V + + G CL + +T VT+ + R +
Sbjct: 2135 YILSQ----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKVTV 2190
Query: 1235 GQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRW-DGDQQLYVTVSSTYSGKLCGLCGN 1293
Q P + G + +G + T ++++W + V S T + GLCG
Sbjct: 2191 DLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGI 2250
Query: 1294 YDGNSDNDHLKLDGSPAGDKEELG---NSWQTDQDEDQECQ-KYQVVNSPSCDSSLQSSM 1349
DG++ ND DGS G E+ +SWQ Q +++ + + D S
Sbjct: 2251 CDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSP---- 2306
Query: 1350 SGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDA 1409
C R+V ++ F C V SF + + D Q C ++ C
Sbjct: 2307 -----CLRMV-SNRTFSACHRFVPPESFCELWIRDTKYVQ----QPCVALTVYVAMCHKF 2356
Query: 1410 GHAVKPWREPHFCPMACPPNSKYSLCAKPC--PDTCHSGFSGMFCSDRCV---EACECNP 1464
H WR +CP C +S Y C C P TC G G + C E C C+
Sbjct: 2357 -HVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSE 2415
Query: 1465 GFVL---SGLECIPRSQCGCLHPAGSYFKVGERW 1495
G +L CIP ++C C G +GE W
Sbjct: 2416 GTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2449
Score = 108 bits (269), Expect = 1e-22
Identities = 102/406 (25%), Positives = 158/406 (38%), Gaps = 63/406 (15%)
Query: 1425 ACPPNSKYSLCAKPCPD-------TCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIP 1475
ACP + C+ D TC + S R C+ C C G + G C
Sbjct: 882 ACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFL 941
Query: 1476 RSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH 1535
+C C YF G++ P C CVC+ + +C C
Sbjct: 942 PEECPCTWKGKEYFP-GDQVMSP-C-HTCVCQRGS-FQCTLHPC---------------- 981
Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
A+TCTA GD HY TFDG F+G C L + + D F V N N
Sbjct: 982 ---ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKS----TSDVSFSVIVENVN------ 1028
Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTI---RLSSNLVLLYTNF 1652
Y + F +SI++ V + P + + R+ ++ +
Sbjct: 1029 -CYSSGMICRKF-ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQE 1086
Query: 1653 GLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW--- 1709
+ + +D V V + GQL GLCGN++ ++++ P+ + + G++W
Sbjct: 1087 HITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV 1146
Query: 1710 KLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASC 1768
+ P++ +P C N + + + K C+IL++ F CH VV +++C
Sbjct: 1147 ECPDTLDPR--------DMCVLNPLREPFAKKECSILLSEV--FEICHPVVDVTWFYSNC 1196
Query: 1769 VHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812
+ CG GD C S+ AYA C Q G A WR CP C
Sbjct: 1197 LTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1242
Score = 107 bits (268), Expect = 1e-22
Identities = 100/406 (24%), Positives = 147/406 (36%), Gaps = 55/406 (13%)
Query: 1037 SRSSTERCPPNARYESCA-------------CPASCKSPRPSCGPLCREGCVCNPGFLFS 1083
SR+ CP + +C+ C + S C GC C G L
Sbjct: 876 SRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRH 935
Query: 1084 DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143
+ C C C + Y PG + SP C T VCQ +
Sbjct: 936 GDACFLPEECPCTWKGKEYFPGDQVMSP--------------------CHT-CVCQRGSF 974
Query: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203
Q HP A +TC YGD HY TFDG F F+G C L + +++D F V +N
Sbjct: 975 QCTLHPCA--STCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STSDVSFSVIVENVNC 1029
Query: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ-TE 1262
G+ C + + + S + G + V G F + +
Sbjct: 1030 YSSGMICRKFISINVGNSLIVFDDDS----GNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1085
Query: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322
+ + WD ++V + G+L GLCGN+D + N+ + + +E G+SW
Sbjct: 1086 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1145
Query: 1323 DQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCM 1382
+ D + V +P + + C L+ FE C V F+ +C+
Sbjct: 1146 VECPDTLDPRDMCVLNPLREPFAKKE------CSILLSE--VFEICHPVVDVTWFYSNCL 1197
Query: 1383 LDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
D CG G C +S C G AV WR P CP C
Sbjct: 1198 TDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 93.2 bits (230), Expect = 3e-18
Identities = 93/378 (24%), Positives = 147/378 (38%), Gaps = 69/378 (18%)
Query: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSY 1598
A C+ D ++TFDG+ Y+L S+S D V + + +++
Sbjct: 2108 ACRCSIFPDLSFVTFDGSHVALFKEAIYIL-----SQSPDEMLTVHVLDCKSANLGHLNW 2162
Query: 1599 IKAVHVTVFDLSISLLRGCKVMLN----GHRVAL------------PVWLAQGRVTIRL- 1641
C VMLN H+V + PVW R R+
Sbjct: 2163 PPF---------------CLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIE 2207
Query: 1642 -SSNLVLLYTNFGLQVRY---DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697
+ ++ ++ T +Q+++ G +VE + S G GLCG + ++ +D D
Sbjct: 2208 DTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGS 2265
Query: 1698 LAG---DSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQ 1754
+ G D +W++P SS +P SC + C +++ + FS
Sbjct: 2266 VVGGAEDPAPFLDSWQVP-SSLTSVGQTRFRPDSCATTDCSP-----CLRMVSNR-TFSA 2318
Query: 1755 CHQVVPPQSSFASCVHGQCGTKGDTTAL---CRSLQAYASLCAQAGQAPAWRNRTFCPMR 1811
CH+ VPP+S + DT + C +L Y ++C + WR +CP
Sbjct: 2319 CHRFVPPESFCELWIR-------DTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL 2371
Query: 1812 CPPGSSYSPCSSPC--PDTC-SSINNPRDCPKALPCAESCECQKGHIL---SGTSCVPLG 1865
C S+Y C + C P TC I P D E C C +G IL C+P
Sbjct: 2372 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2431
Query: 1866 QCGCTDPAGSYHPVGERW 1883
+C CTD G +GE W
Sbjct: 2432 KCACTDSMGVPRALGETW 2449
Score = 81.3 bits (199), Expect = 1e-14
Identities = 105/477 (22%), Positives = 174/477 (36%), Gaps = 44/477 (9%)
Query: 569 KPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM-PSEKPTIPSEKPT 627
+P V + ++ E + PT E+P +S E P P+ +P + P+ T P
Sbjct: 1465 EPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1524
Query: 628 ILTEKPTIP--SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685
TE+P + + T+ +++ P PTE P ++ T S+ E S+P
Sbjct: 1525 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPA--SKGVTASLLAIPHTPESSSLP 1582
Query: 686 TEKPSIPTEKPTISMEETIISTEKPT-ISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK 744
+ + PT M + T + T I P I + P + + K T
Sbjct: 1583 -----VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLM-TKAVTVRGH 1636
Query: 745 PTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTP 804
++P + P +P+ +P SP + + PT + T T P
Sbjct: 1637 GSLPVRTTPLQPSLTASPSSRPVASPGAI---SRSPTSSGSHKAVLTPAVTKVISRTGVP 1693
Query: 805 TEETTISTEKPSIPM-----EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTI 859
S PS P+ +P T E +STEK +P S P
Sbjct: 1694 QPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQ- 1752
Query: 860 PTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEK 919
P P+ P P + T+ T P +P E T + L+ T+ +P ST
Sbjct: 1753 PHPLPSAPPR----PAQHTTMATRSPALPPE--TPAAASLSTATDGLAATPFMSLESTRP 1806
Query: 920 PTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIP 979
+ + P +T++ K + T P +P P S + + T+P
Sbjct: 1807 SQLLSGLP----PDTSLPLAK--VGTSAPVATP--------GPKASVITTPLQPQATTLP 1852
Query: 980 TEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA-ALVMSPHAPSTPMTSVILGTTT 1035
+ T+ P P A P H +P A G A L++ P++ + V GT +
Sbjct: 1853 AQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTAS 1907
Score = 76.6 bits (187), Expect = 3e-13
Identities = 87/428 (20%), Positives = 153/428 (35%), Gaps = 88/428 (20%)
Query: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTSCV 1862
CP G + CS D ++ R C + L PC C C +G + G +C
Sbjct: 883 CPAGQVFVNCSDLHTDL--ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 940
Query: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922
+C CT Y P + +TC C + FQ T P
Sbjct: 941 LPEECPCTWKGKEYFPGDQVMSPCHTCV----CQRGS----FQCTLHP------------ 980
Query: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982
C ++ C G+ HY +FDG AC + LVK
Sbjct: 981 CAST----CTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV------------------ 1018
Query: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042
+F + ++ Y + + +K + + + + S P + ++G
Sbjct: 1019 --SFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1076
Query: 2043 -----------VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSD 2091
+ + +D + ++ + G++ G+CGNF+ + +E+ P + +
Sbjct: 1077 FFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNP 1136
Query: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPV 2149
EF +SW + C L +P C LR A+++C + L + V
Sbjct: 1137 QEFGSSWAAVE----CPDTL------------DPRDMCVLNPLREPFAKKEC-SILLSEV 1179
Query: 2150 WAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2207
+ C +D+T F +C C GG + C ++ A+ C G+ WR C
Sbjct: 1180 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLC 1238
Query: 2208 PLECPAYS 2215
P +C ++
Sbjct: 1239 PYDCDFFN 1246
Score = 76.3 bits (186), Expect = 4e-13
Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 35/322 (10%)
Query: 1999 QVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF-DGNHLLEIEI 2057
QVT+ + +R + Q P +S+ G ++ + ++ +Q+++ + L+ +E
Sbjct: 2178 QVTIDRFNRKVTVDLQPVWPPVSRY-GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEA 2236
Query: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEV---ANSDSEFVNSWKDKDIDPSCQSLLVDE 2114
T + G+CG + + ++L + V A + F++SW+ PS + +
Sbjct: 2237 SKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQT 2292
Query: 2115 QQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFG 2174
+ P C R C + P + C I T ++
Sbjct: 2293 RFRPDSCATTDCSPCLRMVSNRTFSACHRFV--PPESFCELWIRDTKYV----------- 2339
Query: 2175 GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR 2234
Q C AL + A C + WR S +CP C + S+Y C+ +C P DG
Sbjct: 2340 ---QQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG- 2394
Query: 2235 CEGAKVPSAC---AEGCICQPGYVLSEDK---CVPRSQCGCKDAHGGSIPLGKSWVS--S 2286
G P C EGC+C G +L C+P ++C C D+ G LG++W S S
Sbjct: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454
Query: 2287 GCTEKCVCTGGAIQCGDFRCPS 2308
GC + I D CPS
Sbjct: 2455 GCCQHQCQAPDTIVPVDLGCPS 2476
Score = 75.5 bits (184), Expect = 7e-13
Identities = 108/463 (23%), Positives = 166/463 (35%), Gaps = 91/463 (19%)
Query: 654 PTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTIS 713
P PT + + +E+ V P +PTE T P+ + PT S
Sbjct: 1442 PVCPTPQVLDEVTQRCVYLEDCVEPAVW--VPTEALGNETLPPSQGL---------PTPS 1490
Query: 714 PEKPTIPTEKPTIPTEKSTISPEKP-TTPTEKPTIPTEKPTISP---------------- 756
E+P + E P PT + ++P P TT P TE+P +SP
Sbjct: 1491 DEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTAS 1550
Query: 757 EKPTTPTEKPT---ISPEKLTIP--TEKPTIPTEKPTIPTEKPTISTEEPTTPT------ 805
+ P PTE P ++ L IP E ++P T PT E T T
Sbjct: 1551 QLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQT-PTPGMVSGAMETTRVTVIFAGS 1609
Query: 806 EETTISTEKPSIP----MEKPTLPTEETTTSVEETTISTEKLTIPMEKP-----TISTEK 856
T+S+ P P M K + V T + P +P IS
Sbjct: 1610 PNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSP 1669
Query: 857 PTIPTEKPTISP-----------------EKLTIPTEKLTIP-TEKPTIPIEETTISTEK 898
+ + K ++P + + P+ LT+ T +P+ + +
Sbjct: 1670 TSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRSLE 1729
Query: 899 LTIPTEKPTISPEKPTISTEKP---TIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKL 955
+ + TEK +P S P +P+ P P + TT++T +P E P + L
Sbjct: 1730 IVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR-PAQHTTMATRSPALPPETPAAA--SL 1786
Query: 956 TIPTE----KPTISTEKPTIPTEKLTIPTEKPTIPTEK------PTIPTEKLTALRPPHP 1005
+ T+ P +S E T P++ L+ ++P K P K + + P
Sbjct: 1787 STATDGLAATPFMSLES-TRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTP-L 1844
Query: 1006 SPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNA 1048
P AT L A +SP P TP T + T PP A
Sbjct: 1845 QPQATTLPAQTLSPVLPFTP------AAMTQAHPPTHIAPPAA 1881
Score = 75.1 bits (183), Expect = 9e-13
Identities = 93/442 (21%), Positives = 152/442 (34%), Gaps = 86/442 (19%)
Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
+G CQ+ N ++ C +G TFDG Y L G+ +Y L+ + PEG
Sbjct: 133 TGPRCQMVY-----NAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHE--PEG 185
Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRV 2427
+ ++ N S ++ + + ++ E+ ++ +P+
Sbjct: 186 -QSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ 244
Query: 2428 TLWGQRLYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGA 2485
L G Y++ + +++ G I + G GLCGN + + K+D++ SG
Sbjct: 245 QLAG---YVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGK 301
Query: 2486 LTQNLNTFGNSWEVKTED-----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLA 2540
LT ++ F +SW+ + + PR P ++ G G+
Sbjct: 302 LTDDVVEFVHSWQEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGV--------------- 345
Query: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVS 2600
+ C L P PF ACH V+P PF C DLC + C+ L+ +
Sbjct: 346 ---YEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMG---DVATWCRALAEYA-- 395
Query: 2601 SRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIY 2660
Q GRP L+G W + C
Sbjct: 396 -------------RACAQAGRP--LQG---------------WRTQLRQCTVHCKEKAFT 425
Query: 2661 YQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQND 2720
Y + C R +C S I + C G + G GC + C PC+
Sbjct: 426 YNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG----GCVAPAEC---PCEFH 478
Query: 2721 GQCREQGATF-----TCECEVG 2737
G G+ TC C G
Sbjct: 479 GTLYPPGSVVKEDCNTCTCTSG 500
Score = 49.7 bits (117), Expect = 4e-05
Identities = 119/546 (21%), Positives = 192/546 (35%), Gaps = 107/546 (19%)
Query: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284
+P+ ++G E + C P ++E CV C + + +
Sbjct: 2026 APALSIVEGLAEALATTTEANTSTTCVP---IAEQDCVRHI---CLEGQLIRVNQSQHCP 2079
Query: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344
+C G A++ G RC C +CS++ D ++TFDG
Sbjct: 2080 QGAAPPRCGILGLAVRVGGDRCCPLWECAC---------------RCSIFPDLSFVTFDG 2124
Query: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMD---PPRSSIFLQEVITTVYGYKVQ 2401
L Y+L ++ D + V L + N PP + L T ++V
Sbjct: 2125 SHVALFKEAIYILSQSPDEMLT-VHVLDCKSANLGHLNWPPFCLVMLN---MTHLAHQVT 2180
Query: 2402 LQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI---SLPS 2458
+ V + + P R+ G ++T ++ + + +I S S
Sbjct: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240
Query: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALT---QNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
+G GLCG D + ND+ L G++ ++ F +SW+V P+
Sbjct: 2241 KAQG--HGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------------PSS 2285
Query: 2516 EEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
G ++CSP ++ SN T F+ACH+ V PE F E +
Sbjct: 2286 LTSVGQTRFRPDSCATTDCSPCLRMVSNRT------------FSACHRFVPPESFCELWI 2333
Query: 2575 LDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPS---------ILCQPGR--PR 2623
D Q P + + V + S+ L S C+P +
Sbjct: 2334 RDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQD 2393
Query: 2624 GLRGPL---------------RGRL--RQHPRLCLQWHPEPPLADCGCT-SNGIYYQLG- 2664
G+ GPL G + R+H LC+ P A C CT S G+ LG
Sbjct: 2394 GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCI------PEAKCACTDSMGVPRALGE 2447
Query: 2665 --SSFLTEDCSQRCTCASSRI---LLC---EPFSC-RAGEVCTLGNHTQGCFPESPCLQN 2715
+S L+ C +C + + L C P SC R GEV L C + C+ N
Sbjct: 2448 TWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2507
Query: 2716 PCQNDG 2721
+G
Sbjct: 2508 QTLCEG 2513
Score = 32.7 bits (73), Expect = 5.2
Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 19/95 (20%)
Query: 1044 CPPNARYESCACPA--SCK---SPRPSCG---------PLCREGCVCNPGFLFSDNH--C 1087
C + Y C P +C+ SP +CG C EGC C P C
Sbjct: 779 CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 837
Query: 1088 IQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPG 1122
+ + C+C + Y PG HC C G
Sbjct: 838 VPRNQCSCHFQGVDYPPGDS--DIPSLGHCHCKDG 870
>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 241 bits (614), Expect = 1e-62
Identities = 285/1239 (23%), Positives = 454/1239 (36%), Gaps = 248/1239 (20%)
Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI- 1512
+R + +C P ++ S C +C +HPA C C N
Sbjct: 25 ERRLHRAKCAPSYLFS---CFNGGEC--VHPA-----------------FCDCRRFNATG 62
Query: 1513 -RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRP 1571
RCQ +Y + + C A G H TFDG ++ G +Y L
Sbjct: 63 PRCQM--------------VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 108
Query: 1572 CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT-VFDLSISLLRGCKVMLNGHRVALPV 1630
Q F + N+ + G + +AV + V + I L + +V G RV LP
Sbjct: 109 HEPEGQS--FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK--EVTHGGMRVQLPH 164
Query: 1631 WLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
+ R ++ + V++ + +DG+ V + + G GLCGN N + DD
Sbjct: 165 VMGSAR--LQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDD 222
Query: 1691 NLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG--KPSSCQEN--SMADAWNKNCAILI 1746
+ KL D ++ +W+ ++P +P Q+N +M + + C L+
Sbjct: 223 LVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ-CEALL 281
Query: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNR 1805
P PF CH V P ASC C + GD CR+L YA CAQAG+ WR +
Sbjct: 282 RP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 339
Query: 1806 TF-CPMRCPPGS-SYSPCSSPCPDTCSSINNPR-DCPKA-LPCAESCECQKGHILSGTSC 1861
C + C + +Y+ C + CP +C +PR C + + C + C C G I C
Sbjct: 340 LRQCTVHCKEKAFTYNECIACCPASC----HPRASCVDSEIACVDGCYCPNGLIFEDGGC 395
Query: 1862 VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLL 1921
V +C C + G+ +P G + C CTC+ C + C
Sbjct: 396 VAPAECPC-EFHGTLYPPGS--VVKEDCNT-CTCT-SGKWECSTAVCPAE---------- 440
Query: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEG 1981
C + G+ H+ +FDG ++ P C +L K + + F ++ ++
Sbjct: 441 ---------CSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAPCGL 487
Query: 1982 GTEAFRLHEVYIDIYD---AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038
+ + V + ++ QVTL + VL+ + +P + + SS++ V
Sbjct: 488 NQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVR 547
Query: 2039 IKIGVQVKFDGNHL-LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
+GV+V +D L L +++ + G+CG FN +D+ + P ++ F NS
Sbjct: 548 TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 607
Query: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAA--LRAPVWAQCAS 2155
WK +C L+ P + L+ A +A L ++A C++
Sbjct: 608 WKTLS---ACSPLVSGSPLDPCD-----------VHLQAASYSVQACSVLTGEMFAPCSA 653
Query: 2156 RIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
+ P+ C C G LC L + C+ GL C L C A
Sbjct: 654 FLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK 711
Query: 2216 SYTNCLPSCSPSCWDL--------DGRCEGAKVPSACAEGCICQPGYVLSE--DKCVPRS 2265
Y+ C+ C +C DL DG + ++ C EGC C P L D CVPR+
Sbjct: 712 EYSPCVAPCGRTCQDLASPEACGVDGGDDLSR--DECVEGCACPPDTYLDTQADLCVPRN 769
Query: 2266 QCG----------------------CKD--------AHGGSIPLGKSWVSSG-------- 2287
QC CKD A + P G+ +V+
Sbjct: 770 QCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLEL 829
Query: 2288 --------------------CTEKCVCTGGAIQCGDF-----RCP--------------- 2307
C C C G ++ GD CP
Sbjct: 830 SRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM 889
Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
S H + S + + C+ YGD Y TFDG + G L+K+ +
Sbjct: 890 SPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFS 949
Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL-- 2425
V +VE N S + ++ I+ + G L+V + P P L
Sbjct: 950 V---IVENVNCYS---SGMICRKFIS--------INVGNSLIVFDDDSGNP-SPESFLDD 994
Query: 2426 --RVTLWGQRLYLVTDF---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMM 2480
V W + + F + + + R + ++G ++GLCGN+D N+M
Sbjct: 995 KQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1054
Query: 2481 LPSGALTQNLNTFGNSW-EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQL 2539
P N FG+SW V+ D L PR + LR ECS
Sbjct: 1055 TPENLELTNPQEFGSSWAAVECPDTL--DPRDMCVLNP-------LREPFAKKECS---- 1101
Query: 2540 ASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLC 2578
+L++ F CH V F +C+ D C
Sbjct: 1102 --------ILLSE---VFEICHPVVDVTWFYSNCLTDTC 1129
Score = 230 bits (586), Expect = 2e-59
Identities = 201/752 (26%), Positives = 299/752 (39%), Gaps = 77/752 (10%)
Query: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILA---QPCGNSTDPFFRVTAKNEEQ-GQEGVSCL 1211
C +G H TFDG ++ GK +Y L +P G S F + N+ Q G +C
Sbjct: 79 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS----FSIQVHNDPQCGSSPYTCS 134
Query: 1212 SKVYVT-LPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWD 1270
V + + E + L K GG +V LP + +G +V ++ + + WD
Sbjct: 135 RAVSLFFVGEQEIHLAK--EVTHGGMRVQLPHVMGSARLQQLAG-YVIVRHQSAFTLAWD 191
Query: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330
G +Y+ +S G GLCGN + + +D + G D E +SWQ
Sbjct: 192 GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 251
Query: 1331 QKYQVVNSPSCDSSLQSSMSGP-GFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
+ P C +M G C L+ PF+ C +V F SC D+C
Sbjct: 252 PTTSSLPRPPCLQQNPGTMQGVYEQCEALL--RPPFDACHAYVSPLPFTASCTSDLCQSM 309
Query: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWR-EPHFCPMACPPNS-KYSLCAKPCPDTCHSGF 1447
G C ++ C AG ++ WR + C + C + Y+ C CP +CH
Sbjct: 310 GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRA 369
Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVGERWYKPGCKE 1502
S + CV+ C C G + C+ ++C C L+P GS K C
Sbjct: 370 SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV-------VKEDC-N 421
Query: 1503 LCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562
C C S W C A A C+ +GD H+ TFDG + F
Sbjct: 422 TCTCTSGK------WECST--------------AVCPAECSVTGDIHFTTFDGRRYTFPA 461
Query: 1563 TCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFD---LSISLLRGCKV 1619
TC Y+L + SRS + F V+ N G + + +++V V + ++L + V
Sbjct: 462 TCQYILAK---SRSSGT-FTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDV 517
Query: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHL-VEVTVPSSYGGQLCG 1678
+L +P + RLSS + + TN G++V YD L + + V + G
Sbjct: 518 LLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVG 577
Query: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP-SSCQENSMADA 1737
LCG +N N+ DD L P G +WK + P LV G P C + A +
Sbjct: 578 LCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP---LVSGSPLDPCDVHLQAAS 634
Query: 1738 WN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796
++ + C++L F+ C + P F C C + LC +L YA LC +
Sbjct: 635 YSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRH 690
Query: 1797 GQAPAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP-------KALPCAESC 1848
G +R R C + C YSPC +PC TC + +P C C E C
Sbjct: 691 GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC 750
Query: 1849 ECQKGHILSGTS--CVPLGQCGCTDPAGSYHP 1878
C L + CVP QC C Y P
Sbjct: 751 ACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP 782
Score = 179 bits (454), Expect = 3e-44
Identities = 144/476 (30%), Positives = 196/476 (41%), Gaps = 63/476 (13%)
Query: 1032 GTTTTSRSSTERCPPNA-RYESC--ACPASCKSPRPSCGP---LCREGCVCNPGFLFSDN 1085
G T R T C A Y C CPASC PR SC C +GC C G +F D
Sbjct: 335 GWRTQLRQCTVHCKEKAFTYNECIACCPASCH-PRASCVDSEIACVDGCYCPNGLIFEDG 393
Query: 1086 HCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY 1145
C+ + C C ++ Y PG+ E C C +G++
Sbjct: 394 GCVAPAECPCEFHGTLYPPGSV-----VKEDCN------------------TCTCTSGKW 430
Query: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG- 1204
C A C V GD H+ TFDGR + F C YILA+ + T F VT +N G
Sbjct: 431 ECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGT---FTVTLQNAPCGL 487
Query: 1205 -QEGVSCLSKVYVTL---PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL-GASGRFVEL 1259
Q+G +C+ V V L P VTL + L+ Q +P + S F+ +
Sbjct: 488 NQDG-ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRV 546
Query: 1260 QTEFGLRVRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGN 1318
+T G+RV +D + +LY+ V + GLCG ++GN+ +D L G P + GN
Sbjct: 547 RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 606
Query: 1319 SWQTDQDEDQECQKYQVVNSP--SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAAS 1376
SW+T C V SP CD LQ++ C L T F C +
Sbjct: 607 SWKT----LSACSPL-VSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVP 659
Query: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436
+F+ C D C + Q LC ++ C+ G V C ++C + +YS C
Sbjct: 660 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
Query: 1437 KPCPDTCHSGFSGMFCS---------DRCVEACECNPGFVLSGLE--CIPRSQCGC 1481
PC TC S C D CVE C C P L C+PR+QC C
Sbjct: 718 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 773
Score = 164 bits (414), Expect = 1e-39
Identities = 201/850 (23%), Positives = 306/850 (36%), Gaps = 170/850 (20%)
Query: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
+C+ G+ H +FDG + + + LV P F I H + G+ +
Sbjct: 78 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS--FSIQV-HNDPQCGSSPYTCS 134
Query: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049
+ + + V +V LP + + ++ + Y IV + + +DG
Sbjct: 135 RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHV--MGSARLQQLAGYVIVRHQSAFTLAWDG 192
Query: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID----P 2105
+ I++ G G+CGN N + +D+L+ S ++ + EFV+SW+++ + P
Sbjct: 193 ASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP 252
Query: 2106 SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 2165
+ SL P Q+NP ++ E+CEA LR P A C + + PF
Sbjct: 253 TTSSL-----PRPPCLQQNPG------TMQGVYEQCEALLRPPFDA-CHAYVSPLPFTAS 300
Query: 2166 CANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYS-SYTNCLPS 2223
C + LC+ G C+AL + C G WR C + C + +Y C+
Sbjct: 301 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 360
Query: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSW 2283
C SC C +++ AC +GC C G + + CV ++C C + HG P G S
Sbjct: 361 CPASCHPR-ASCVDSEI--ACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPG-SV 415
Query: 2284 VSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFD 2343
V C C CT G +C CP+ +CSV GD + TFD
Sbjct: 416 VKEDCNT-CTCTSGKWECSTAVCPA---------------------ECSVTGDIHFTTFD 453
Query: 2344 GFSYRLQGRMTYVLIK---------TVDVLPEGV--EPLLVEGRNKM--DPPRSSIFLQE 2390
G Y Y+L K T+ P G+ + V+ + + PR + L
Sbjct: 454 GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTL-- 511
Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPY-----------------RPNEHLRVTL--WG 2431
QAG L+ + K+ PY R N +RV G
Sbjct: 512 -----------TQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560
Query: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491
RLYL D V GLCG ++ N ++D + P G
Sbjct: 561 LRLYLQVDQRWVED------------------TVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
Query: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVL 2550
FGNSW+ + A L +G + C Q AS S QAC VL
Sbjct: 603 LFGNSWKTLS-------------------ACSPLVSGSPLDPCDVHLQAASYSVQACSVL 643
Query: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYD 2610
FA C ++P P+ E C D C P C L+ + R H
Sbjct: 644 TGEM--FAPCSAFLSPVPYFEQCRRDACRCGQP-----CLCATLAHYAHLCRRH------ 690
Query: 2611 TLPSILCQPGRPRGLRGPLRGRLRQHPRLC-LQWHPEPPLADCGCTSNGIY------YQL 2663
GL R RL C P +A CG T +
Sbjct: 691 -------------GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDG 737
Query: 2664 GSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQC 2723
G ++C + C C L + C C+ H QG + P + + G C
Sbjct: 738 GDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC--HFQGV--DYPPGDSDIPSLGHC 793
Query: 2724 REQGATFTCE 2733
+ +C+
Sbjct: 794 HCKDGVMSCD 803
Score = 152 bits (383), Expect = 6e-36
Identities = 234/1056 (22%), Positives = 367/1056 (34%), Gaps = 235/1056 (22%)
Query: 598 PTISTEKPTIPSEKPNMPSEK-PTIPSEKPTILTEKPTIPSEKPTIPSEKP-TISTEKPT 655
PT + T+P PS+ PT E+P + E P P+ +P + P T + P
Sbjct: 1399 PTEALGNETLP------PSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1452
Query: 656 VPTEEPTTPTEETTTSMEEPVIPT--EKPSIPTEKPS---------------------IP 692
TEEP T T++++P+ T + P+ PTE P+ +
Sbjct: 1453 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVA 1512
Query: 693 TEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKSTISPEKPT 739
+ PT M + T + T+ SP P P + P + T
Sbjct: 1513 LQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTT 1572
Query: 740 TPTEKPTI-PTEKPTISP----EKPT---------TPTEKPTISPEKLTIPTEKPTIPTE 785
P T P+ +P SP PT TP IS + PT+ +
Sbjct: 1573 PPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS--AS 1630
Query: 786 KPTIP-TEKPTISTEEPTTPTE----ETTISTEKP----SIPMEKPTLPTEETTTSV--- 833
P+ P T T + + P +P E +STEK S PM P P S
Sbjct: 1631 SPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR 1690
Query: 834 --EETTISTEKLTIPMEKP---TISTE------------KPTIPTEKPTISPEKLTIPTE 876
+ TT++T +P E P ++ST + T P++ + P ++P
Sbjct: 1691 PAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLA 1750
Query: 877 KL----TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKP----TISTEKP-------- 920
K+ + T P + T + + T+P + T+SP P ++ P
Sbjct: 1751 KVGTSAPVATPGPKASVITTPLQPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPA 1808
Query: 921 -----------TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTE------ 960
T+PT +P E T S + T K I +++++PT
Sbjct: 1809 AGTAPGLLLGATLPTSG-VLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAE 1867
Query: 961 ----KPTISTEKPTIPT----------EKLTIPTEKPTIPTEKPTIPTEKLTALRPP--- 1003
+ T +T P P L +PT T P + + L P
Sbjct: 1868 GGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAE 1927
Query: 1004 -HPSPTATGLAA-----LVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPA 1057
H + LAA P S P S++ G ++TE
Sbjct: 1928 AHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEA-------------- 1973
Query: 1058 SCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHC 1117
+ +C P+ + CV + C++ + N ++HC
Sbjct: 1974 ---NTSTTCVPIAEQDCV--------RHICLEG----------------QLIRVNQSQHC 2006
Query: 1118 RCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGK 1177
P +CG + G C + C ++ D +VTFDG H +
Sbjct: 2007 ---PQGAAP---PRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKE 2060
Query: 1178 CTYILAQPCGNSTDPFFRVTAKNEEQGQEG-----VSCLSKVYVTLPESTVTLLKGRRTL 1232
YIL+Q S D V + + G CL + +T VT+ + R +
Sbjct: 2061 AIYILSQ----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKV 2116
Query: 1233 VGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRW-DGDQQLYVTVSSTYSGKLCGLC 1291
Q P + G + +G + T ++++W + V S T + GLC
Sbjct: 2117 TVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLC 2176
Query: 1292 GNYDGNSDNDHLKLDGSPAGDKEELG---NSWQTDQDEDQECQ-KYQVVNSPSCDSSLQS 1347
G DG++ ND DGS G E+ +SWQ Q +++ + + D S
Sbjct: 2177 GICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSP-- 2234
Query: 1348 SMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQ 1407
C R+V ++ F C V SF + + D Q C ++ C
Sbjct: 2235 -------CLRMV-SNRTFSACHRFVPPESFCELWIRDTKYVQ----QPCVALTVYVAMCH 2282
Query: 1408 DAGHAVKPWREPHFCPMACPPNSKYSLCAKPC--PDTCHSGFSGMFCSDRCV---EACEC 1462
H WR +CP C +S Y C C P TC G G + C E C C
Sbjct: 2283 KF-HVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVC 2341
Query: 1463 NPGFVL---SGLECIPRSQCGCLHPAGSYFKVGERW 1495
+ G +L CIP ++C C G +GE W
Sbjct: 2342 SEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2377
Score = 108 bits (269), Expect = 1e-22
Identities = 102/406 (25%), Positives = 158/406 (38%), Gaps = 63/406 (15%)
Query: 1425 ACPPNSKYSLCAKPCPD-------TCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIP 1475
ACP + C+ D TC + S R C+ C C G + G C
Sbjct: 810 ACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFL 869
Query: 1476 RSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH 1535
+C C YF G++ P C CVC+ + +C C
Sbjct: 870 PEECPCTWKGKEYFP-GDQVMSP-C-HTCVCQRGS-FQCTLHPC---------------- 909
Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
A+TCTA GD HY TFDG F+G C L + + D F V N N
Sbjct: 910 ---ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKS----TSDVSFSVIVENVN------ 956
Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTI---RLSSNLVLLYTNF 1652
Y + F +SI++ V + P + + R+ ++ +
Sbjct: 957 -CYSSGMICRKF-ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQE 1014
Query: 1653 GLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW--- 1709
+ + +D V V + GQL GLCGN++ ++++ P+ + + G++W
Sbjct: 1015 HITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV 1074
Query: 1710 KLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASC 1768
+ P++ +P C N + + + K C+IL++ F CH VV +++C
Sbjct: 1075 ECPDTLDPR--------DMCVLNPLREPFAKKECSILLSEV--FEICHPVVDVTWFYSNC 1124
Query: 1769 VHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812
+ CG GD C S+ AYA C Q G A WR CP C
Sbjct: 1125 LTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1170
Score = 107 bits (268), Expect = 1e-22
Identities = 100/406 (24%), Positives = 147/406 (36%), Gaps = 55/406 (13%)
Query: 1037 SRSSTERCPPNARYESCA-------------CPASCKSPRPSCGPLCREGCVCNPGFLFS 1083
SR+ CP + +C+ C + S C GC C G L
Sbjct: 804 SRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRH 863
Query: 1084 DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143
+ C C C + Y PG + SP C T VCQ +
Sbjct: 864 GDACFLPEECPCTWKGKEYFPGDQVMSP--------------------CHT-CVCQRGSF 902
Query: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203
Q HP A +TC YGD HY TFDG F F+G C L + +++D F V +N
Sbjct: 903 QCTLHPCA--STCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STSDVSFSVIVENVNC 957
Query: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ-TE 1262
G+ C + + + S + G + V G F + +
Sbjct: 958 YSSGMICRKFISINVGNSLIVFDDDS----GNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1013
Query: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322
+ + WD ++V + G+L GLCGN+D + N+ + + +E G+SW
Sbjct: 1014 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1073
Query: 1323 DQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCM 1382
+ D + V +P + + C L+ FE C V F+ +C+
Sbjct: 1074 VECPDTLDPRDMCVLNPLREPFAKKE------CSILLSE--VFEICHPVVDVTWFYSNCL 1125
Query: 1383 LDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
D CG G C +S C G AV WR P CP C
Sbjct: 1126 TDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 93.2 bits (230), Expect = 3e-18
Identities = 93/378 (24%), Positives = 147/378 (38%), Gaps = 69/378 (18%)
Query: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSY 1598
A C+ D ++TFDG+ Y+L S+S D V + + +++
Sbjct: 2036 ACRCSIFPDLSFVTFDGSHVALFKEAIYIL-----SQSPDEMLTVHVLDCKSANLGHLNW 2090
Query: 1599 IKAVHVTVFDLSISLLRGCKVMLN----GHRVAL------------PVWLAQGRVTIRL- 1641
C VMLN H+V + PVW R R+
Sbjct: 2091 PPF---------------CLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIE 2135
Query: 1642 -SSNLVLLYTNFGLQVRY---DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697
+ ++ ++ T +Q+++ G +VE + S G GLCG + ++ +D D
Sbjct: 2136 DTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGS 2193
Query: 1698 LAG---DSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQ 1754
+ G D +W++P SS +P SC + C +++ + FS
Sbjct: 2194 VVGGAEDPAPFLDSWQVP-SSLTSVGQTRFRPDSCATTDCSP-----CLRMVSNR-TFSA 2246
Query: 1755 CHQVVPPQSSFASCVHGQCGTKGDTTAL---CRSLQAYASLCAQAGQAPAWRNRTFCPMR 1811
CH+ VPP+S + DT + C +L Y ++C + WR +CP
Sbjct: 2247 CHRFVPPESFCELWIR-------DTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL 2299
Query: 1812 CPPGSSYSPCSSPC--PDTC-SSINNPRDCPKALPCAESCECQKGHIL---SGTSCVPLG 1865
C S+Y C + C P TC I P D E C C +G IL C+P
Sbjct: 2300 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2359
Query: 1866 QCGCTDPAGSYHPVGERW 1883
+C CTD G +GE W
Sbjct: 2360 KCACTDSMGVPRALGETW 2377
Score = 80.5 bits (197), Expect = 2e-14
Identities = 107/485 (22%), Positives = 175/485 (36%), Gaps = 60/485 (12%)
Query: 569 KPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM-PSEKPTIPSEKPT 627
+P V + ++ E + PT E+P +S E P P+ +P + P+ T P
Sbjct: 1393 EPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1452
Query: 628 ILTEKPTIP--SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685
TE+P + + T+ +++ P PTE P ++ T S+ E S+P
Sbjct: 1453 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPA--SKGVTASLLAIPHTPESSSLP 1510
Query: 686 TEKPSIPTEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKST 732
+ + PT M + T + T+ SP P P +
Sbjct: 1511 -----VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHG 1565
Query: 733 ISPEKPTTPTEKPTI-PTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPT 791
P + T P T P+ +P S P + PT S + T T + +P
Sbjct: 1566 SLPVRTTPPQPSLTASPSSRPVAS---PGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQ 1622
Query: 792 EKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPT 851
S P+TP + E+ +P T E +STEK +P
Sbjct: 1623 PTQAQSASSPSTPLTVAGTAAEQ---------VPVSPLATRSLEIVLSTEKGEAGHSQPM 1673
Query: 852 ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911
S P P P+ P P + T+ T P +P E T + L+ T+ +P
Sbjct: 1674 GSPASPQ-PHPLPSAPPR----PAQHTTMATRSPALPPE--TPAAASLSTATDGLAATPF 1726
Query: 912 KPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTI 971
ST + + P +T++ K + T P +P P S +
Sbjct: 1727 MSLESTRPSQLLSGLP----PDTSLPLAK--VGTSAPVATP--------GPKASVITTPL 1772
Query: 972 PTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA-ALVMSPHAPSTPMTSVI 1030
+ T+P + T+ P P A P H +P A G A L++ P++ + V
Sbjct: 1773 QPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVA 1830
Query: 1031 LGTTT 1035
GT +
Sbjct: 1831 EGTAS 1835
Score = 76.6 bits (187), Expect = 3e-13
Identities = 87/428 (20%), Positives = 153/428 (35%), Gaps = 88/428 (20%)
Query: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTSCV 1862
CP G + CS D ++ R C + L PC C C +G + G +C
Sbjct: 811 CPAGQVFVNCSDLHTDL--ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 868
Query: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922
+C CT Y P + +TC C + FQ T P
Sbjct: 869 LPEECPCTWKGKEYFPGDQVMSPCHTCV----CQRGS----FQCTLHP------------ 908
Query: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982
C ++ C G+ HY +FDG AC + LVK
Sbjct: 909 CAST----CTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV------------------ 946
Query: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042
+F + ++ Y + + +K + + + + S P + ++G
Sbjct: 947 --SFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1004
Query: 2043 -----------VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSD 2091
+ + +D + ++ + G++ G+CGNF+ + +E+ P + +
Sbjct: 1005 FFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNP 1064
Query: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPV 2149
EF +SW + C L +P C LR A+++C + L + V
Sbjct: 1065 QEFGSSWAAVE----CPDTL------------DPRDMCVLNPLREPFAKKEC-SILLSEV 1107
Query: 2150 WAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2207
+ C +D+T F +C C GG + C ++ A+ C G+ WR C
Sbjct: 1108 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLC 1166
Query: 2208 PLECPAYS 2215
P +C ++
Sbjct: 1167 PYDCDFFN 1174
Score = 76.3 bits (186), Expect = 4e-13
Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 35/322 (10%)
Query: 1999 QVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF-DGNHLLEIEI 2057
QVT+ + +R + Q P +S+ G ++ + ++ +Q+++ + L+ +E
Sbjct: 2106 QVTIDRFNRKVTVDLQPVWPPVSRY-GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEA 2164
Query: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEV---ANSDSEFVNSWKDKDIDPSCQSLLVDE 2114
T + G+CG + + ++L + V A + F++SW+ PS + +
Sbjct: 2165 SKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQT 2220
Query: 2115 QQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFG 2174
+ P C R C + P + C I T ++
Sbjct: 2221 RFRPDSCATTDCSPCLRMVSNRTFSACHRFV--PPESFCELWIRDTKYV----------- 2267
Query: 2175 GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR 2234
Q C AL + A C + WR S +CP C + S+Y C+ +C P DG
Sbjct: 2268 ---QQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG- 2322
Query: 2235 CEGAKVPSAC---AEGCICQPGYVLSEDK---CVPRSQCGCKDAHGGSIPLGKSWVS--S 2286
G P C EGC+C G +L C+P ++C C D+ G LG++W S S
Sbjct: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
Query: 2287 GCTEKCVCTGGAIQCGDFRCPS 2308
GC + I D CPS
Sbjct: 2383 GCCQHQCQAPDTIVPVDLGCPS 2404
Score = 75.1 bits (183), Expect = 9e-13
Identities = 93/442 (21%), Positives = 152/442 (34%), Gaps = 86/442 (19%)
Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
+G CQ+ N ++ C +G TFDG Y L G+ +Y L+ + PEG
Sbjct: 61 TGPRCQMVY-----NAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHE--PEG 113
Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRV 2427
+ ++ N S ++ + + ++ E+ ++ +P+
Sbjct: 114 -QSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ 172
Query: 2428 TLWGQRLYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGA 2485
L G Y++ + +++ G I + G GLCGN + + K+D++ SG
Sbjct: 173 QLAG---YVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGK 229
Query: 2486 LTQNLNTFGNSWEVKTED-----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLA 2540
LT ++ F +SW+ + + PR P ++ G G+
Sbjct: 230 LTDDVVEFVHSWQEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGV--------------- 273
Query: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVS 2600
+ C L P PF ACH V+P PF C DLC + C+ L+ +
Sbjct: 274 ---YEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMG---DVATWCRALAEYA-- 323
Query: 2601 SRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIY 2660
Q GRP L+G W + C
Sbjct: 324 -------------RACAQAGRP--LQG---------------WRTQLRQCTVHCKEKAFT 353
Query: 2661 YQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQND 2720
Y + C R +C S I + C G + G GC + C PC+
Sbjct: 354 YNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG----GCVAPAEC---PCEFH 406
Query: 2721 GQCREQGATF-----TCECEVG 2737
G G+ TC C G
Sbjct: 407 GTLYPPGSVVKEDCNTCTCTSG 428
Score = 74.7 bits (182), Expect = 1e-12
Identities = 109/472 (23%), Positives = 174/472 (36%), Gaps = 95/472 (20%)
Query: 647 PTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIS 706
P + P PT + + +E+ V P +PTE T P+ +
Sbjct: 1363 PRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEPAVW--VPTEALGNETLPPSQGL------ 1414
Query: 707 TEKPTISPEKPTIPTEKPTIPTEKSTISPEKP-TTPTEKPTIPTEKPTISP--------- 756
PT S E+P + E P PT + ++P P TT P TE+P +SP
Sbjct: 1415 ---PTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQ 1471
Query: 757 -------EKPTTPTEKPT---ISPEKLTIP--TEKPTIPTEKPTIPTEKPTISTEEPTTP 804
+ P PTE P ++ L IP E ++P T PT E T
Sbjct: 1472 PLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQT-PTPGMVSGAMETTRV 1530
Query: 805 T------EETTISTEKPSIPMEKPTLPTEETT----------TSVEETTISTEKLTIPME 848
T T+S+ P P + L T+ T T+ + +++ + P+
Sbjct: 1531 TVIFAGSPNITVSSRSP--PAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVA 1588
Query: 849 KPTISTEKPTIP-TEKPTISP-----------------EKLTIPTEKLTIP-TEKPTIPI 889
P + PT + K ++P + + P+ LT+ T +P+
Sbjct: 1589 SPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPV 1648
Query: 890 EETTISTEKLTIPTEKPTISPEKPTISTEKP---TIPTEKPTIPTEETTISTEKLTIPTE 946
+ ++ + TEK +P S P +P+ P P + TT++T +P E
Sbjct: 1649 SPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR-PAQHTTMATRSPALPPE 1707
Query: 947 KPTISPEKLTIPTE----KPTISTEKPTIPTEKLTIPTEKPTIPTEK------PTIPTEK 996
P + L+ T+ P +S E T P++ L+ ++P K P K
Sbjct: 1708 TPAAA--SLSTATDGLAATPFMSLES-TRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPK 1764
Query: 997 LTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNA 1048
+ + P P AT L A +SP P TP T + T PP A
Sbjct: 1765 ASVITTP-LQPQATTLPAQTLSPVLPFTP------AAMTQAHPPTHIAPPAA 1809
Score = 49.7 bits (117), Expect = 4e-05
Identities = 119/546 (21%), Positives = 192/546 (35%), Gaps = 107/546 (19%)
Query: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284
+P+ ++G E + C P ++E CV C + + +
Sbjct: 1954 APALSIVEGLAEALATTTEANTSTTCVP---IAEQDCVRHI---CLEGQLIRVNQSQHCP 2007
Query: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344
+C G A++ G RC C +CS++ D ++TFDG
Sbjct: 2008 QGAAPPRCGILGLAVRVGGDRCCPLWECAC---------------RCSIFPDLSFVTFDG 2052
Query: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMD---PPRSSIFLQEVITTVYGYKVQ 2401
L Y+L ++ D + V L + N PP + L T ++V
Sbjct: 2053 SHVALFKEAIYILSQSPDEMLT-VHVLDCKSANLGHLNWPPFCLVMLN---MTHLAHQVT 2108
Query: 2402 LQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI---SLPS 2458
+ V + + P R+ G ++T ++ + + +I S S
Sbjct: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
Query: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALT---QNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
+G GLCG D + ND+ L G++ ++ F +SW+V P+
Sbjct: 2169 KAQG--HGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------------PSS 2213
Query: 2516 EEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
G ++CSP ++ SN T F+ACH+ V PE F E +
Sbjct: 2214 LTSVGQTRFRPDSCATTDCSPCLRMVSNRT------------FSACHRFVPPESFCELWI 2261
Query: 2575 LDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPS---------ILCQPGR--PR 2623
D Q P + + V + S+ L S C+P +
Sbjct: 2262 RDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQD 2321
Query: 2624 GLRGPL---------------RGRL--RQHPRLCLQWHPEPPLADCGCT-SNGIYYQLG- 2664
G+ GPL G + R+H LC+ P A C CT S G+ LG
Sbjct: 2322 GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCI------PEAKCACTDSMGVPRALGE 2375
Query: 2665 --SSFLTEDCSQRCTCASSRI---LLC---EPFSC-RAGEVCTLGNHTQGCFPESPCLQN 2715
+S L+ C +C + + L C P SC R GEV L C + C+ N
Sbjct: 2376 TWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2435
Query: 2716 PCQNDG 2721
+G
Sbjct: 2436 QTLCEG 2441
Score = 32.7 bits (73), Expect = 5.2
Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 19/95 (20%)
Query: 1044 CPPNARYESCACPA--SCK---SPRPSCG---------PLCREGCVCNPGFLFSDNH--C 1087
C + Y C P +C+ SP +CG C EGC C P C
Sbjct: 707 CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 765
Query: 1088 IQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPG 1122
+ + C+C + Y PG HC C G
Sbjct: 766 VPRNQCSCHFQGVDYPPGDS--DIPSLGHCHCKDG 798
>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 241 bits (614), Expect = 1e-62
Identities = 285/1239 (23%), Positives = 454/1239 (36%), Gaps = 248/1239 (20%)
Query: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRI- 1512
+R + +C P ++ S C +C +HPA C C N
Sbjct: 97 ERRLHRAKCAPSYLFS---CFNGGEC--VHPA-----------------FCDCRRFNATG 134
Query: 1513 -RCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRP 1571
RCQ +Y + + C A G H TFDG ++ G +Y L
Sbjct: 135 PRCQM--------------VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGR 180
Query: 1572 CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVT-VFDLSISLLRGCKVMLNGHRVALPV 1630
Q F + N+ + G + +AV + V + I L + +V G RV LP
Sbjct: 181 HEPEGQS--FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK--EVTHGGMRVQLPH 236
Query: 1631 WLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
+ R ++ + V++ + +DG+ V + + G GLCGN N + DD
Sbjct: 237 VMGSAR--LQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDD 294
Query: 1691 NLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGG--KPSSCQEN--SMADAWNKNCAILI 1746
+ KL D ++ +W+ ++P +P Q+N +M + + C L+
Sbjct: 295 LVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ-CEALL 353
Query: 1747 NPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNR 1805
P PF CH V P ASC C + GD CR+L YA CAQAG+ WR +
Sbjct: 354 RP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQ 411
Query: 1806 TF-CPMRCPPGS-SYSPCSSPCPDTCSSINNPR-DCPKA-LPCAESCECQKGHILSGTSC 1861
C + C + +Y+ C + CP +C +PR C + + C + C C G I C
Sbjct: 412 LRQCTVHCKEKAFTYNECIACCPASC----HPRASCVDSEIACVDGCYCPNGLIFEDGGC 467
Query: 1862 VPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLL 1921
V +C C + G+ +P G + C CTC+ C + C
Sbjct: 468 VAPAECPC-EFHGTLYPPGS--VVKEDCNT-CTCT-SGKWECSTAVCPAE---------- 512
Query: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEG 1981
C + G+ H+ +FDG ++ P C +L K + + F ++ ++
Sbjct: 513 ---------CSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAPCGL 559
Query: 1982 GTEAFRLHEVYIDIYD---AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038
+ + V + ++ QVTL + VL+ + +P + + SS++ V
Sbjct: 560 NQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVR 619
Query: 2039 IKIGVQVKFDGNHL-LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
+GV+V +D L L +++ + G+CG FN +D+ + P ++ F NS
Sbjct: 620 TNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNS 679
Query: 2098 WKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAA--LRAPVWAQCAS 2155
WK +C L+ P + L+ A +A L ++A C++
Sbjct: 680 WKTLS---ACSPLVSGSPLDPCD-----------VHLQAASYSVQACSVLTGEMFAPCSA 725
Query: 2156 RIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS 2215
+ P+ C C G LC L + C+ GL C L C A
Sbjct: 726 FLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASK 783
Query: 2216 SYTNCLPSCSPSCWDL--------DGRCEGAKVPSACAEGCICQPGYVLSE--DKCVPRS 2265
Y+ C+ C +C DL DG + ++ C EGC C P L D CVPR+
Sbjct: 784 EYSPCVAPCGRTCQDLASPEACGVDGGDDLSR--DECVEGCACPPDTYLDTQADLCVPRN 841
Query: 2266 QCG----------------------CKD--------AHGGSIPLGKSWVSSG-------- 2287
QC CKD A + P G+ +V+
Sbjct: 842 QCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLEL 901
Query: 2288 --------------------CTEKCVCTGGAIQCGDF-----RCP--------------- 2307
C C C G ++ GD CP
Sbjct: 902 SRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVM 961
Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
S H + S + + C+ YGD Y TFDG + G L+K+ +
Sbjct: 962 SPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFS 1021
Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHL-- 2425
V +VE N S + ++ I+ + G L+V + P P L
Sbjct: 1022 V---IVENVNCYS---SGMICRKFIS--------INVGNSLIVFDDDSGNP-SPESFLDD 1066
Query: 2426 --RVTLWGQRLYLVTDF---ELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMM 2480
V W + + F + + + R + ++G ++GLCGN+D N+M
Sbjct: 1067 KQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMR 1126
Query: 2481 LPSGALTQNLNTFGNSW-EVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQL 2539
P N FG+SW V+ D L PR + LR ECS
Sbjct: 1127 TPENLELTNPQEFGSSWAAVECPDTL--DPRDMCVLNP-------LREPFAKKECS---- 1173
Query: 2540 ASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLC 2578
+L++ F CH V F +C+ D C
Sbjct: 1174 --------ILLSE---VFEICHPVVDVTWFYSNCLTDTC 1201
Score = 230 bits (586), Expect = 2e-59
Identities = 201/752 (26%), Positives = 299/752 (39%), Gaps = 77/752 (10%)
Query: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILA---QPCGNSTDPFFRVTAKNEEQ-GQEGVSCL 1211
C +G H TFDG ++ GK +Y L +P G S F + N+ Q G +C
Sbjct: 151 CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS----FSIQVHNDPQCGSSPYTCS 206
Query: 1212 SKVYVT-LPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWD 1270
V + + E + L K GG +V LP + +G +V ++ + + WD
Sbjct: 207 RAVSLFFVGEQEIHLAK--EVTHGGMRVQLPHVMGSARLQQLAG-YVIVRHQSAFTLAWD 263
Query: 1271 GDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC 1330
G +Y+ +S G GLCGN + + +D + G D E +SWQ
Sbjct: 264 GASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPG 323
Query: 1331 QKYQVVNSPSCDSSLQSSMSGP-GFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ 1389
+ P C +M G C L+ PF+ C +V F SC D+C
Sbjct: 324 PTTSSLPRPPCLQQNPGTMQGVYEQCEALL--RPPFDACHAYVSPLPFTASCTSDLCQSM 381
Query: 1390 GLQHLLCTHMSTMTTTCQDAGHAVKPWR-EPHFCPMACPPNS-KYSLCAKPCPDTCHSGF 1447
G C ++ C AG ++ WR + C + C + Y+ C CP +CH
Sbjct: 382 GDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRA 441
Query: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGC-----LHPAGSYFKVGERWYKPGCKE 1502
S + CV+ C C G + C+ ++C C L+P GS K C
Sbjct: 442 SCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSV-------VKEDC-N 493
Query: 1503 LCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMG 1562
C C S W C A A C+ +GD H+ TFDG + F
Sbjct: 494 TCTCTSGK------WECST--------------AVCPAECSVTGDIHFTTFDGRRYTFPA 533
Query: 1563 TCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFD---LSISLLRGCKV 1619
TC Y+L + SRS + F V+ N G + + +++V V + ++L + V
Sbjct: 534 TCQYILAK---SRSSGT-FTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDV 589
Query: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHL-VEVTVPSSYGGQLCG 1678
+L +P + RLSS + + TN G++V YD L + + V + G
Sbjct: 590 LLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVG 649
Query: 1679 LCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKP-SSCQENSMADA 1737
LCG +N N+ DD L P G +WK + P LV G P C + A +
Sbjct: 650 LCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP---LVSGSPLDPCDVHLQAAS 706
Query: 1738 WN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796
++ + C++L F+ C + P F C C + LC +L YA LC +
Sbjct: 707 YSVQACSVLTGEM--FAPCSAFLSPVPYFEQCRRDAC--RCGQPCLCATLAHYAHLCRRH 762
Query: 1797 GQAPAWRNR-TFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCP-------KALPCAESC 1848
G +R R C + C YSPC +PC TC + +P C C E C
Sbjct: 763 GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGC 822
Query: 1849 ECQKGHILSGTS--CVPLGQCGCTDPAGSYHP 1878
C L + CVP QC C Y P
Sbjct: 823 ACPPDTYLDTQADLCVPRNQCSCHFQGVDYPP 854
Score = 179 bits (454), Expect = 3e-44
Identities = 144/476 (30%), Positives = 196/476 (41%), Gaps = 63/476 (13%)
Query: 1032 GTTTTSRSSTERCPPNA-RYESC--ACPASCKSPRPSCGP---LCREGCVCNPGFLFSDN 1085
G T R T C A Y C CPASC PR SC C +GC C G +F D
Sbjct: 407 GWRTQLRQCTVHCKEKAFTYNECIACCPASCH-PRASCVDSEIACVDGCYCPNGLIFEDG 465
Query: 1086 HCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQY 1145
C+ + C C ++ Y PG+ E C C +G++
Sbjct: 466 GCVAPAECPCEFHGTLYPPGSV-----VKEDCN------------------TCTCTSGKW 502
Query: 1146 GCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQG- 1204
C A C V GD H+ TFDGR + F C YILA+ + T F VT +N G
Sbjct: 503 ECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGT---FTVTLQNAPCGL 559
Query: 1205 -QEGVSCLSKVYVTL---PESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL-GASGRFVEL 1259
Q+G +C+ V V L P VTL + L+ Q +P + S F+ +
Sbjct: 560 NQDG-ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRV 618
Query: 1260 QTEFGLRVRWDGD-QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGN 1318
+T G+RV +D + +LY+ V + GLCG ++GN+ +D L G P + GN
Sbjct: 619 RTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGN 678
Query: 1319 SWQTDQDEDQECQKYQVVNSP--SCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAAS 1376
SW+T C V SP CD LQ++ C L T F C +
Sbjct: 679 SWKT----LSACSPL-VSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVP 731
Query: 1377 FFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCA 1436
+F+ C D C + Q LC ++ C+ G V C ++C + +YS C
Sbjct: 732 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789
Query: 1437 KPCPDTCHSGFSGMFCS---------DRCVEACECNPGFVLSGLE--CIPRSQCGC 1481
PC TC S C D CVE C C P L C+PR+QC C
Sbjct: 790 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC 845
Score = 164 bits (414), Expect = 1e-39
Identities = 201/850 (23%), Positives = 306/850 (36%), Gaps = 170/850 (20%)
Query: 1930 VCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLH 1989
+C+ G+ H +FDG + + + LV P F I H + G+ +
Sbjct: 150 ICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS--FSIQV-HNDPQCGSSPYTCS 206
Query: 1990 EVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDG 2049
+ + + V +V LP + + ++ + Y IV + + +DG
Sbjct: 207 RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHV--MGSARLQQLAGYVIVRHQSAFTLAWDG 264
Query: 2050 NHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDID----P 2105
+ I++ G G+CGN N + +D+L+ S ++ + EFV+SW+++ + P
Sbjct: 265 ASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP 324
Query: 2106 SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 2165
+ SL P Q+NP ++ E+CEA LR P A C + + PF
Sbjct: 325 TTSSL-----PRPPCLQQNPG------TMQGVYEQCEALLRPPFDA-CHAYVSPLPFTAS 372
Query: 2166 CANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNS-SFCPLECPAYS-SYTNCLPS 2223
C + LC+ G C+AL + C G WR C + C + +Y C+
Sbjct: 373 CTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIAC 432
Query: 2224 CSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSW 2283
C SC C +++ AC +GC C G + + CV ++C C + HG P G S
Sbjct: 433 CPASCHPR-ASCVDSEI--ACVDGCYCPNGLIFEDGGCVAPAECPC-EFHGTLYPPG-SV 487
Query: 2284 VSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFD 2343
V C C CT G +C CP+ +CSV GD + TFD
Sbjct: 488 VKEDCNT-CTCTSGKWECSTAVCPA---------------------ECSVTGDIHFTTFD 525
Query: 2344 GFSYRLQGRMTYVLIK---------TVDVLPEGV--EPLLVEGRNKM--DPPRSSIFLQE 2390
G Y Y+L K T+ P G+ + V+ + + PR + L
Sbjct: 526 GRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTL-- 583
Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPY-----------------RPNEHLRVTL--WG 2431
QAG L+ + K+ PY R N +RV G
Sbjct: 584 -----------TQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 632
Query: 2432 QRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491
RLYL D V GLCG ++ N ++D + P G
Sbjct: 633 LRLYLQVDQRWVED------------------TVGLCGTFNGNTQDDFLSPVGVPESTPQ 674
Query: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVL 2550
FGNSW+ + A L +G + C Q AS S QAC VL
Sbjct: 675 LFGNSWKTLS-------------------ACSPLVSGSPLDPCDVHLQAASYSVQACSVL 715
Query: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYD 2610
FA C ++P P+ E C D C P C L+ + R H
Sbjct: 716 TGEM--FAPCSAFLSPVPYFEQCRRDACRCGQP-----CLCATLAHYAHLCRRH------ 762
Query: 2611 TLPSILCQPGRPRGLRGPLRGRLRQHPRLC-LQWHPEPPLADCGCTSNGIY------YQL 2663
GL R RL C P +A CG T +
Sbjct: 763 -------------GLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDG 809
Query: 2664 GSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQC 2723
G ++C + C C L + C C+ H QG + P + + G C
Sbjct: 810 GDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSC--HFQGV--DYPPGDSDIPSLGHC 865
Query: 2724 REQGATFTCE 2733
+ +C+
Sbjct: 866 HCKDGVMSCD 875
Score = 152 bits (383), Expect = 6e-36
Identities = 234/1056 (22%), Positives = 367/1056 (34%), Gaps = 235/1056 (22%)
Query: 598 PTISTEKPTIPSEKPNMPSEK-PTIPSEKPTILTEKPTIPSEKPTIPSEKP-TISTEKPT 655
PT + T+P PS+ PT E+P + E P P+ +P + P T + P
Sbjct: 1471 PTEALGNETLP------PSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1524
Query: 656 VPTEEPTTPTEETTTSMEEPVIPT--EKPSIPTEKPS---------------------IP 692
TEEP T T++++P+ T + P+ PTE P+ +
Sbjct: 1525 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVA 1584
Query: 693 TEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKSTISPEKPT 739
+ PT M + T + T+ SP P P + P + T
Sbjct: 1585 LQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHGSLPVRTT 1644
Query: 740 TPTEKPTI-PTEKPTISP----EKPT---------TPTEKPTISPEKLTIPTEKPTIPTE 785
P T P+ +P SP PT TP IS + PT+ +
Sbjct: 1645 PPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS--AS 1702
Query: 786 KPTIP-TEKPTISTEEPTTPTE----ETTISTEKP----SIPMEKPTLPTEETTTSV--- 833
P+ P T T + + P +P E +STEK S PM P P S
Sbjct: 1703 SPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR 1762
Query: 834 --EETTISTEKLTIPMEKP---TISTE------------KPTIPTEKPTISPEKLTIPTE 876
+ TT++T +P E P ++ST + T P++ + P ++P
Sbjct: 1763 PAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLA 1822
Query: 877 KL----TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKP----TISTEKP-------- 920
K+ + T P + T + + T+P + T+SP P ++ P
Sbjct: 1823 KVGTSAPVATPGPKASVITTPLQPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPA 1880
Query: 921 -----------TIPTEKPTIPTEETTISTEKLT---IPTEKPTISPEKLTIPTE------ 960
T+PT +P E T S + T K I +++++PT
Sbjct: 1881 AGTAPGLLLGATLPTSG-VLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAE 1939
Query: 961 ----KPTISTEKPTIPT----------EKLTIPTEKPTIPTEKPTIPTEKLTALRPP--- 1003
+ T +T P P L +PT T P + + L P
Sbjct: 1940 GGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAE 1999
Query: 1004 -HPSPTATGLAA-----LVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPA 1057
H + LAA P S P S++ G ++TE
Sbjct: 2000 AHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEA-------------- 2045
Query: 1058 SCKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHC 1117
+ +C P+ + CV + C++ + N ++HC
Sbjct: 2046 ---NTSTTCVPIAEQDCV--------RHICLEG----------------QLIRVNQSQHC 2078
Query: 1118 RCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGK 1177
P +CG + G C + C ++ D +VTFDG H +
Sbjct: 2079 ---PQGAAP---PRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKE 2132
Query: 1178 CTYILAQPCGNSTDPFFRVTAKNEEQGQEG-----VSCLSKVYVTLPESTVTLLKGRRTL 1232
YIL+Q S D V + + G CL + +T VT+ + R +
Sbjct: 2133 AIYILSQ----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKV 2188
Query: 1233 VGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRW-DGDQQLYVTVSSTYSGKLCGLC 1291
Q P + G + +G + T ++++W + V S T + GLC
Sbjct: 2189 TVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLC 2248
Query: 1292 GNYDGNSDNDHLKLDGSPAGDKEELG---NSWQTDQDEDQECQ-KYQVVNSPSCDSSLQS 1347
G DG++ ND DGS G E+ +SWQ Q +++ + + D S
Sbjct: 2249 GICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSP-- 2306
Query: 1348 SMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQ 1407
C R+V ++ F C V SF + + D Q C ++ C
Sbjct: 2307 -------CLRMV-SNRTFSACHRFVPPESFCELWIRDTKYVQ----QPCVALTVYVAMCH 2354
Query: 1408 DAGHAVKPWREPHFCPMACPPNSKYSLCAKPC--PDTCHSGFSGMFCSDRCV---EACEC 1462
H WR +CP C +S Y C C P TC G G + C E C C
Sbjct: 2355 KF-HVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVC 2413
Query: 1463 NPGFVL---SGLECIPRSQCGCLHPAGSYFKVGERW 1495
+ G +L CIP ++C C G +GE W
Sbjct: 2414 SEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2449
Score = 108 bits (269), Expect = 1e-22
Identities = 102/406 (25%), Positives = 158/406 (38%), Gaps = 63/406 (15%)
Query: 1425 ACPPNSKYSLCAKPCPD-------TCHSGFSGMFCSDR--CVEACECNPGFVLSGLECIP 1475
ACP + C+ D TC + S R C+ C C G + G C
Sbjct: 882 ACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFL 941
Query: 1476 RSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCH 1535
+C C YF G++ P C CVC+ + +C C
Sbjct: 942 PEECPCTWKGKEYFP-GDQVMSP-C-HTCVCQRGS-FQCTLHPC---------------- 981
Query: 1536 AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILE 1595
A+TCTA GD HY TFDG F+G C L + + D F V N N
Sbjct: 982 ---ASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKS----TSDVSFSVIVENVN------ 1028
Query: 1596 VSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTI---RLSSNLVLLYTNF 1652
Y + F +SI++ V + P + + R+ ++ +
Sbjct: 1029 -CYSSGMICRKF-ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQE 1086
Query: 1653 GLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAW--- 1709
+ + +D V V + GQL GLCGN++ ++++ P+ + + G++W
Sbjct: 1087 HITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV 1146
Query: 1710 KLPESSEPGCFLVGGKPSSCQENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASC 1768
+ P++ +P C N + + + K C+IL++ F CH VV +++C
Sbjct: 1147 ECPDTLDPR--------DMCVLNPLREPFAKKECSILLSEV--FEICHPVVDVTWFYSNC 1196
Query: 1769 VHGQCGTK--GDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812
+ CG GD C S+ AYA C Q G A WR CP C
Sbjct: 1197 LTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDC 1242
Score = 107 bits (268), Expect = 1e-22
Identities = 100/406 (24%), Positives = 147/406 (36%), Gaps = 55/406 (13%)
Query: 1037 SRSSTERCPPNARYESCA-------------CPASCKSPRPSCGPLCREGCVCNPGFLFS 1083
SR+ CP + +C+ C + S C GC C G L
Sbjct: 876 SRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRH 935
Query: 1084 DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143
+ C C C + Y PG + SP C T VCQ +
Sbjct: 936 GDACFLPEECPCTWKGKEYFPGDQVMSP--------------------CHT-CVCQRGSF 974
Query: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203
Q HP A +TC YGD HY TFDG F F+G C L + +++D F V +N
Sbjct: 975 QCTLHPCA--STCTAYGDRHYRTFDGLPFDFVGACKVHLVK---STSDVSFSVIVENVNC 1029
Query: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQ-TE 1262
G+ C + + + S + G + V G F + +
Sbjct: 1030 YSSGMICRKFISINVGNSLIVFDDDS----GNPSPESFLDDKQEVHTWRVGFFTLVHFPQ 1085
Query: 1263 FGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQT 1322
+ + WD ++V + G+L GLCGN+D + N+ + + +E G+SW
Sbjct: 1086 EHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA 1145
Query: 1323 DQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCM 1382
+ D + V +P + + C L+ FE C V F+ +C+
Sbjct: 1146 VECPDTLDPRDMCVLNPLREPFAKKE------CSILLSE--VFEICHPVVDVTWFYSNCL 1197
Query: 1383 LDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
D CG G C +S C G AV WR P CP C
Sbjct: 1198 TDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 93.2 bits (230), Expect = 3e-18
Identities = 93/378 (24%), Positives = 147/378 (38%), Gaps = 69/378 (18%)
Query: 1539 AATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSY 1598
A C+ D ++TFDG+ Y+L S+S D V + + +++
Sbjct: 2108 ACRCSIFPDLSFVTFDGSHVALFKEAIYIL-----SQSPDEMLTVHVLDCKSANLGHLNW 2162
Query: 1599 IKAVHVTVFDLSISLLRGCKVMLN----GHRVAL------------PVWLAQGRVTIRL- 1641
C VMLN H+V + PVW R R+
Sbjct: 2163 PPF---------------CLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIE 2207
Query: 1642 -SSNLVLLYTNFGLQVRY---DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRK 1697
+ ++ ++ T +Q+++ G +VE + S G GLCG + ++ +D D
Sbjct: 2208 DTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGS 2265
Query: 1698 LAG---DSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQ 1754
+ G D +W++P SS +P SC + C +++ + FS
Sbjct: 2266 VVGGAEDPAPFLDSWQVP-SSLTSVGQTRFRPDSCATTDCSP-----CLRMVSNR-TFSA 2318
Query: 1755 CHQVVPPQSSFASCVHGQCGTKGDTTAL---CRSLQAYASLCAQAGQAPAWRNRTFCPMR 1811
CH+ VPP+S + DT + C +L Y ++C + WR +CP
Sbjct: 2319 CHRFVPPESFCELWIR-------DTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFL 2371
Query: 1812 CPPGSSYSPCSSPC--PDTC-SSINNPRDCPKALPCAESCECQKGHIL---SGTSCVPLG 1865
C S+Y C + C P TC I P D E C C +G IL C+P
Sbjct: 2372 CSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEA 2431
Query: 1866 QCGCTDPAGSYHPVGERW 1883
+C CTD G +GE W
Sbjct: 2432 KCACTDSMGVPRALGETW 2449
Score = 80.5 bits (197), Expect = 2e-14
Identities = 107/485 (22%), Positives = 175/485 (36%), Gaps = 60/485 (12%)
Query: 569 KPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM-PSEKPTIPSEKPT 627
+P V + ++ E + PT E+P +S E P P+ +P + P+ T P
Sbjct: 1465 EPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPV 1524
Query: 628 ILTEKPTIP--SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIP 685
TE+P + + T+ +++ P PTE P ++ T S+ E S+P
Sbjct: 1525 TATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPA--SKGVTASLLAIPHTPESSSLP 1582
Query: 686 TEKPSIPTEKPTISMEETIISTEKPTI-------------SPEKPTIPTEKPTIPTEKST 732
+ + PT M + T + T+ SP P P +
Sbjct: 1583 -----VALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFPLMTKAVTVRGHG 1637
Query: 733 ISPEKPTTPTEKPTI-PTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPT 791
P + T P T P+ +P S P + PT S + T T + +P
Sbjct: 1638 SLPVRTTPPQPSLTASPSSRPVAS---PGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQ 1694
Query: 792 EKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPT 851
S P+TP + E+ +P T E +STEK +P
Sbjct: 1695 PTQAQSASSPSTPLTVAGTAAEQ---------VPVSPLATRSLEIVLSTEKGEAGHSQPM 1745
Query: 852 ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911
S P P P+ P P + T+ T P +P E T + L+ T+ +P
Sbjct: 1746 GSPASPQ-PHPLPSAPPR----PAQHTTMATRSPALPPE--TPAAASLSTATDGLAATPF 1798
Query: 912 KPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTI 971
ST + + P +T++ K + T P +P P S +
Sbjct: 1799 MSLESTRPSQLLSGLP----PDTSLPLAK--VGTSAPVATP--------GPKASVITTPL 1844
Query: 972 PTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLA-ALVMSPHAPSTPMTSVI 1030
+ T+P + T+ P P A P H +P A G A L++ P++ + V
Sbjct: 1845 QPQATTLPAQ--TLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVA 1902
Query: 1031 LGTTT 1035
GT +
Sbjct: 1903 EGTAS 1907
Score = 76.6 bits (187), Expect = 3e-13
Identities = 87/428 (20%), Positives = 153/428 (35%), Gaps = 88/428 (20%)
Query: 1812 CPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTSCV 1862
CP G + CS D ++ R C + L PC C C +G + G +C
Sbjct: 883 CPAGQVFVNCSDLHTDL--ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACF 940
Query: 1863 PLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLR 1922
+C CT Y P + +TC C + FQ T P
Sbjct: 941 LPEECPCTWKGKEYFPGDQVMSPCHTCV----CQRGS----FQCTLHP------------ 980
Query: 1923 CRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGG 1982
C ++ C G+ HY +FDG AC + LVK
Sbjct: 981 CAST----CTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDV------------------ 1018
Query: 1983 TEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIG 2042
+F + ++ Y + + +K + + + + S P + ++G
Sbjct: 1019 --SFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVG 1076
Query: 2043 -----------VQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSD 2091
+ + +D + ++ + G++ G+CGNF+ + +E+ P + +
Sbjct: 1077 FFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNP 1136
Query: 2092 SEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRR--AREKCEAALRAPV 2149
EF +SW + C L +P C LR A+++C + L + V
Sbjct: 1137 QEFGSSWAAVE----CPDTL------------DPRDMCVLNPLREPFAKKEC-SILLSEV 1179
Query: 2150 WAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2207
+ C +D+T F +C C GG + C ++ A+ C G+ WR C
Sbjct: 1180 FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLC 1238
Query: 2208 PLECPAYS 2215
P +C ++
Sbjct: 1239 PYDCDFFN 1246
Score = 76.3 bits (186), Expect = 4e-13
Identities = 77/322 (23%), Positives = 129/322 (40%), Gaps = 35/322 (10%)
Query: 1999 QVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKF-DGNHLLEIEI 2057
QVT+ + +R + Q P +S+ G ++ + ++ +Q+++ + L+ +E
Sbjct: 2178 QVTIDRFNRKVTVDLQPVWPPVSRY-GFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEA 2236
Query: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEV---ANSDSEFVNSWKDKDIDPSCQSLLVDE 2114
T + G+CG + + ++L + V A + F++SW+ PS + +
Sbjct: 2237 SKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV----PSSLTSVGQT 2292
Query: 2115 QQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFG 2174
+ P C R C + P + C I T ++
Sbjct: 2293 RFRPDSCATTDCSPCLRMVSNRTFSACHRFV--PPESFCELWIRDTKYV----------- 2339
Query: 2175 GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGR 2234
Q C AL + A C + WR S +CP C + S+Y C+ +C P DG
Sbjct: 2340 ---QQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDG- 2394
Query: 2235 CEGAKVPSAC---AEGCICQPGYVLSEDK---CVPRSQCGCKDAHGGSIPLGKSWVS--S 2286
G P C EGC+C G +L C+P ++C C D+ G LG++W S S
Sbjct: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454
Query: 2287 GCTEKCVCTGGAIQCGDFRCPS 2308
GC + I D CPS
Sbjct: 2455 GCCQHQCQAPDTIVPVDLGCPS 2476
Score = 75.1 bits (183), Expect = 9e-13
Identities = 93/442 (21%), Positives = 152/442 (34%), Gaps = 86/442 (19%)
Query: 2308 SGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEG 2367
+G CQ+ N ++ C +G TFDG Y L G+ +Y L+ + PEG
Sbjct: 133 TGPRCQMVY-----NAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHE--PEG 185
Query: 2368 VEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRV 2427
+ ++ N S ++ + + ++ E+ ++ +P+
Sbjct: 186 -QSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ 244
Query: 2428 TLWGQRLYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGA 2485
L G Y++ + +++ G I + G GLCGN + + K+D++ SG
Sbjct: 245 QLAG---YVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGK 301
Query: 2486 LTQNLNTFGNSWEVKTED-----ALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLA 2540
LT ++ F +SW+ + + PR P ++ G G+
Sbjct: 302 LTDDVVEFVHSWQEQAPNQPPGPTTSSLPRP-PCLQQNPGTMQGV--------------- 345
Query: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVS 2600
+ C L P PF ACH V+P PF C DLC + C+ L+ +
Sbjct: 346 ---YEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMG---DVATWCRALAEYA-- 395
Query: 2601 SRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIY 2660
Q GRP L+G W + C
Sbjct: 396 -------------RACAQAGRP--LQG---------------WRTQLRQCTVHCKEKAFT 425
Query: 2661 YQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQND 2720
Y + C R +C S I + C G + G GC + C PC+
Sbjct: 426 YNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG----GCVAPAEC---PCEFH 478
Query: 2721 GQCREQGATF-----TCECEVG 2737
G G+ TC C G
Sbjct: 479 GTLYPPGSVVKEDCNTCTCTSG 500
Score = 74.3 bits (181), Expect = 2e-12
Identities = 108/465 (23%), Positives = 172/465 (36%), Gaps = 95/465 (20%)
Query: 654 PTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTIS 713
P PT + + +E+ V P +PTE T P+ + PT S
Sbjct: 1442 PVCPTPQVLDEVTQRCVYLEDCVEPAVW--VPTEALGNETLPPSQGL---------PTPS 1490
Query: 714 PEKPTIPTEKPTIPTEKSTISPEKP-TTPTEKPTIPTEKPTISP---------------- 756
E+P + E P PT + ++P P TT P TE+P +SP
Sbjct: 1491 DEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQQPLELTAS 1550
Query: 757 EKPTTPTEKPT---ISPEKLTIP--TEKPTIPTEKPTIPTEKPTISTEEPTTPT------ 805
+ P PTE P ++ L IP E ++P T PT E T T
Sbjct: 1551 QLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQT-PTPGMVSGAMETTRVTVIFAGS 1609
Query: 806 EETTISTEKPSIPMEKPTLPTEETT----------TSVEETTISTEKLTIPMEKPTISTE 855
T+S+ P P + L T+ T T+ + +++ + P+ P +
Sbjct: 1610 PNITVSSRSP--PAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISR 1667
Query: 856 KPTIP-TEKPTISP-----------------EKLTIPTEKLTIP-TEKPTIPIEETTIST 896
PT + K ++P + + P+ LT+ T +P+ +
Sbjct: 1668 SPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLATRS 1727
Query: 897 EKLTIPTEKPTISPEKPTISTEKP---TIPTEKPTIPTEETTISTEKLTIPTEKPTISPE 953
++ + TEK +P S P +P+ P P + TT++T +P E P +
Sbjct: 1728 LEIVLSTEKGEAGHSQPMGSPASPQPHPLPSAPPR-PAQHTTMATRSPALPPETPAAA-- 1784
Query: 954 KLTIPTE----KPTISTEKPTIPTEKLTIPTEKPTIPTEK------PTIPTEKLTALRPP 1003
L+ T+ P +S E T P++ L+ ++P K P K + + P
Sbjct: 1785 SLSTATDGLAATPFMSLES-TRPSQLLSGLPPDTSLPLAKVGTSAPVATPGPKASVITTP 1843
Query: 1004 HPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNA 1048
P AT L A +SP P TP T + T PP A
Sbjct: 1844 -LQPQATTLPAQTLSPVLPFTP------AAMTQAHPPTHIAPPAA 1881
Score = 49.7 bits (117), Expect = 4e-05
Identities = 119/546 (21%), Positives = 192/546 (35%), Gaps = 107/546 (19%)
Query: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWV 2284
+P+ ++G E + C P ++E CV C + + +
Sbjct: 2026 APALSIVEGLAEALATTTEANTSTTCVP---IAEQDCVRHI---CLEGQLIRVNQSQHCP 2079
Query: 2285 SSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDG 2344
+C G A++ G RC C +CS++ D ++TFDG
Sbjct: 2080 QGAAPPRCGILGLAVRVGGDRCCPLWECAC---------------RCSIFPDLSFVTFDG 2124
Query: 2345 FSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMD---PPRSSIFLQEVITTVYGYKVQ 2401
L Y+L ++ D + V L + N PP + L T ++V
Sbjct: 2125 SHVALFKEAIYILSQSPDEMLT-VHVLDCKSANLGHLNWPPFCLVMLN---MTHLAHQVT 2180
Query: 2402 LQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVI---SLPS 2458
+ V + + P R+ G ++T ++ + + +I S S
Sbjct: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240
Query: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALT---QNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
+G GLCG D + ND+ L G++ ++ F +SW+V P+
Sbjct: 2241 KAQG--HGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------------PSS 2285
Query: 2516 EEGQGAELGLRTGLQVSECSP-EQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCV 2574
G ++CSP ++ SN T F+ACH+ V PE F E +
Sbjct: 2286 LTSVGQTRFRPDSCATTDCSPCLRMVSNRT------------FSACHRFVPPESFCELWI 2333
Query: 2575 LDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPS---------ILCQPGR--PR 2623
D Q P + + V + S+ L S C+P +
Sbjct: 2334 RDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQD 2393
Query: 2624 GLRGPL---------------RGRL--RQHPRLCLQWHPEPPLADCGCT-SNGIYYQLG- 2664
G+ GPL G + R+H LC+ P A C CT S G+ LG
Sbjct: 2394 GILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCI------PEAKCACTDSMGVPRALGE 2447
Query: 2665 --SSFLTEDCSQRCTCASSRI---LLC---EPFSC-RAGEVCTLGNHTQGCFPESPCLQN 2715
+S L+ C +C + + L C P SC R GEV L C + C+ N
Sbjct: 2448 TWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2507
Query: 2716 PCQNDG 2721
+G
Sbjct: 2508 QTLCEG 2513
Score = 32.7 bits (73), Expect = 5.2
Identities = 25/95 (26%), Positives = 33/95 (34%), Gaps = 19/95 (20%)
Query: 1044 CPPNARYESCACPA--SCK---SPRPSCG---------PLCREGCVCNPGFLFSDNH--C 1087
C + Y C P +C+ SP +CG C EGC C P C
Sbjct: 779 CEASKEYSPCVAPCGRTCQDLASPE-ACGVDGGDDLSRDECVEGCACPPDTYLDTQADLC 837
Query: 1088 IQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPG 1122
+ + C+C + Y PG HC C G
Sbjct: 838 VPRNQCSCHFQGVDYPPGDS--DIPSLGHCHCKDG 870
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 231 bits (589), Expect = 8e-60
Identities = 165/500 (33%), Positives = 226/500 (45%), Gaps = 71/500 (14%)
Query: 1422 CP--MACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEA----------CECNPGFVLS 1469
CP + CPP+ + C TC S CS+ + + C+C L
Sbjct: 996 CPSLVGCPPSQLLPPGPQHCCPTCAEALSN--CSEGLLGSELAPPDPCYTCQCQDLTWLC 1053
Query: 1470 GLECIPRSQC---------------------GCLHPAGSYFKVGERWYKPGCKELCVCES 1508
+ P C C+H G GERW C C C +
Sbjct: 1054 IHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQ-GREVASGERWTVDTCTS-CSCMA 1111
Query: 1509 NNRIRCQPWRCRAQEFCGQQDGIY----GCHAQ---GAATCTASGDPHYLTFDGALHHFM 1561
+RCQ RC CG C + A+C A GDPHY TFDG L HF
Sbjct: 1112 GT-VRCQSQRCSPLS-CGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQ 1169
Query: 1562 GTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVML 1621
G+C+YVL + C S F V TN++RG V++ + V V + D+++ LL+ V +
Sbjct: 1170 GSCSYVLAKDCHSGD----FSVHVTNDDRGRS-GVAWTQEVAVLLGDMAVRLLQDGAVTV 1224
Query: 1622 NGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCG 1681
+GH VALP +L + + + L + V+L+ GLQV +DG VEV+VP SY G+ CGLCG
Sbjct: 1225 DGHPVALP-FLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCG 1283
Query: 1682 NYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGK---PSSCQENSMADAW 1738
N+N + DD P+ L G +W++ E PG G+ P
Sbjct: 1284 NFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREA 1343
Query: 1739 NKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQC----GTKGDTTALCRSLQAYASLCA 1794
N C +L PFS+CH VVPP+ FA+CV+ C G+ D LC +L+AYAS C
Sbjct: 1344 NARCGVL--KSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSAD-ACLCDALEAYASHCR 1400
Query: 1795 QAGQAPAWRNRTFCPMRCP--PGSSYSPCSSPCPDTCSSINNP-----RDCPKALPCAES 1847
QAG P WR T C + CP G + C PCP TC + + P C + PC
Sbjct: 1401 QAGVTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVR--PCVPG 1458
Query: 1848 CECQKGHILSGTSCVPLGQC 1867
C+C G + C+P C
Sbjct: 1459 CQCPAGLVEHEAHCIPPEAC 1478
Score = 197 bits (502), Expect = 9e-50
Identities = 144/509 (28%), Positives = 210/509 (41%), Gaps = 63/509 (12%)
Query: 1007 PTATGLAALVMSPHAPS--TPMTSVILGTTTTSRSSTERCPPNARY-------------E 1051
P+ G + P P P + L + +E PP+ Y +
Sbjct: 997 PSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIHQ 1056
Query: 1052 SC---ACPASCK-SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAE 1107
+C +CP S + +P SC P+CR A + +C + G
Sbjct: 1057 ACPELSCPLSERHTPPGSCCPVCR------------------APTQSCVHQGREVASGER 1098
Query: 1108 WFSPNCTEHCRCWPGSRVECQISQC-----GTHTVCQLKNGQYGCHPYAGTATCLVYGDP 1162
W CT C C G+ V CQ +C G L G A+C+ +GDP
Sbjct: 1099 WTVDTCTS-CSCMAGT-VRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDP 1156
Query: 1163 HYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPEST 1222
HY TFDGR F G C+Y+LA+ C + F V N+++G+ GV+ +V V L +
Sbjct: 1157 HYRTFDGRLLHFQGSCSYVLAKDCHSGD---FSVHVTNDDRGRSGVAWTQEVAVLLGDMA 1213
Query: 1223 VTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSST 1282
V LL+ V G V LP + +++ G V L + GL+V WDG Q+ V+V +
Sbjct: 1214 VRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGS 1273
Query: 1283 YSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQD--EDQECQKYQVVNSPS 1340
Y G+ CGLCGN++G + +D +G + GNSWQ + + C + V+ P
Sbjct: 1274 YQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVD-PC 1332
Query: 1341 CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGF---QGLQHLLCT 1397
+ ++ CG L + PF C V FF +C+ D+C LC
Sbjct: 1333 RAAGYRARREANARCGVLKSS--PFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCD 1390
Query: 1398 HMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSL--CAKPCPDTCHS-----GFSGM 1450
+ + C+ AG WR P C + CP + C PCP TC + G
Sbjct: 1391 ALEAYASHCRQAG-VTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAA 1449
Query: 1451 FCSDRCVEACECNPGFVLSGLECIPRSQC 1479
C CV C+C G V CIP C
Sbjct: 1450 HCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
Score = 159 bits (401), Expect = 5e-38
Identities = 167/624 (26%), Positives = 251/624 (40%), Gaps = 101/624 (16%)
Query: 1700 GDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINP-QGPFSQCHQV 1758
G+ G+ W P+S+ C C E + A + + P QGP C
Sbjct: 900 GEEHPEGSRWVPPDSACSSCV--------CHEGVVTCARIQCISSCAQPRQGPHDCC--- 948
Query: 1759 VPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCA------QAGQAPAWR-NRTFCP-- 1809
PQ S C +G S Q A C Q P+ R +R CP
Sbjct: 949 --PQCS-------DCEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSL 999
Query: 1810 MRCPPGSSYSPCSSPCPDTCSSINNPRDCPKAL---------PCAESCECQKGHILSGTS 1860
+ CPP P C TC+ + +C + L PC +C+CQ L
Sbjct: 1000 VGCPPSQLLPPGPQHCCPTCAEALS--NCSEGLLGSELAPPDPCY-TCQCQDLTWLCIHQ 1056
Query: 1861 CVPLGQCGCTD---PAGSYHPV-----------------GERWYTENTCTRLCTCSVHN- 1899
P C ++ P GS PV GERW T +TCT C+C
Sbjct: 1057 ACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGERW-TVDTCTS-CSCMAGTV 1114
Query: 1900 ---NITCFQSTCKPNQICWALDGLL--RCRASGVGVCQLPGESHYVSFDGSNHSIPDACT 1954
+ C +C P++ G RC C G+ HY +FDG +C+
Sbjct: 1115 RCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPAS-CMAFGDPHYRTFDGRLLHFQGSCS 1173
Query: 1955 LVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQ 2014
VL K CH F + ++ + G + EV + + D V L + V ++
Sbjct: 1174 YVLAKDCHSGD----FSVHVTND-DRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHP 1228
Query: 2015 VTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFND 2074
V LP + + P + V+ I++ + G+QV +DG +E+ +P +Y G+ CG+CGNFN
Sbjct: 1229 VALPFLQE-PLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNG 1287
Query: 2075 EEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADL 2134
+D+L P + S++ F NSW+ L + A ++ +P CRAA
Sbjct: 1288 FAQDDLQGPEGLLLPSEAAFGNSWQ-------VSEGLWPGRPCSAGREVDP---CRAAGY 1337
Query: 2135 RRARE---KCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQA---LCQALQAFG 2188
R RE +C L++ +++C + + PF C LC G A LC AL+A+
Sbjct: 1338 RARREANARC-GVLKSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYA 1396
Query: 2189 ATCQSQGLKPPLWRNSSFCPLECPAYSSYT--NCLPSCSPSCWDLD---GRCEGAKVPSA 2243
+ C+ G+ P WR + C + CP + C P C +C++ G A
Sbjct: 1397 SHCRQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGEL-AAHCVRP 1454
Query: 2244 CAEGCICQPGYVLSEDKCVPRSQC 2267
C GC C G V E C+P C
Sbjct: 1455 CVPGCQCPAGLVEHEAHCIPPEAC 1478
Score = 127 bits (318), Expect = 2e-28
Identities = 141/568 (24%), Positives = 193/568 (33%), Gaps = 110/568 (19%)
Query: 2191 CQSQGLKPPLWR-NSSFCP--LECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEG 2247
C+ Q PP R + CP + CP C P+C + C + S A
Sbjct: 979 CEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPP 1038
Query: 2248 -----CICQPGYVLSEDKCVPRSQCGCKDAH--------------------GGSIPLGKS 2282
C CQ L + P C + H G + G+
Sbjct: 1039 DPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGER 1098
Query: 2283 WVSSGCTEKCVCTGGAIQCGDFRCPSGSHC------QLTSDNSNSNCVSDKSEQCSVYGD 2336
W CT C C G ++C RC S C L+ + C+ + C +GD
Sbjct: 1099 WTVDTCTS-CSCMAGTVRCQSQRC-SPLSCGPDKAPALSPGSCCPRCLP-RPASCMAFGD 1155
Query: 2337 PRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSI-FLQEVITTV 2395
P Y TFDG QG +YVL K V D RS + + QEV +
Sbjct: 1156 PHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVHV------TNDDRGRSGVAWTQEVAVLL 1209
Query: 2396 YGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVIS 2455
V+L + V+ +A+P+ L V L G + L L V + G+ +S
Sbjct: 1210 GDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVS 1269
Query: 2456 LPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAE 2515
+P Y+G GLCGN++ ++D+ P G L + FGNSW+V
Sbjct: 1270 VPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQV---------------- 1313
Query: 2516 EEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVL 2575
EG G +V C + R PF+ CH V PEPF CV
Sbjct: 1314 SEGLWPGRPCSAGREVDPCRAAGYRARREANARCGVLKSSPFSRCHAVVPPEPFFAACVY 1373
Query: 2576 DLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRPRGLRGPLRGRLRQ 2635
DLC+ + C L + R Q G RG
Sbjct: 1374 DLCACGPGSSADACLCDALEAYASHCR---------------QAGVTPTWRG-------- 1410
Query: 2636 HPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQRC--TCASSRILLCEPFS--- 2690
P LC+ GC L F+ ++C C TC + I L E +
Sbjct: 1411 -PTLCV----------VGC-------PLERGFVFDECGPPCPRTCFNQHIPLGELAAHCV 1452
Query: 2691 --CRAGEVCTLG--NHTQGCFPESPCLQ 2714
C G C G H C P C Q
Sbjct: 1453 RPCVPGCQCPAGLVEHEAHCIPPEACPQ 1480
Score = 42.7 bits (99), Expect = 0.005
Identities = 43/136 (31%), Positives = 51/136 (37%), Gaps = 29/136 (21%)
Query: 2191 CQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCIC 2250
CQ + P L + S P CP S CL S DG E + P+ E C C
Sbjct: 811 CQKKPCPPALCPHPSPGPCFCPVCHS---CL---SQGREHQDG--EEFEGPAGSCEWCRC 862
Query: 2251 QPGYV----------------LSEDKCVPRSQCGCKDAHGGSIPLGKSWV--SSGCTEKC 2292
Q G V C PR + GC AHG P G WV S C+ C
Sbjct: 863 QAGQVSCVRLQCPPLPCKLQVTERGSCCPRCR-GCL-AHGEEHPEGSRWVPPDSACSS-C 919
Query: 2293 VCTGGAIQCGDFRCPS 2308
VC G + C +C S
Sbjct: 920 VCHEGVVTCARIQCIS 935
Score = 42.0 bits (97), Expect = 0.009
Identities = 40/136 (29%), Positives = 51/136 (37%), Gaps = 21/136 (15%)
Query: 2207 CPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPS--ACAEGCICQPGYVLSEDK-CVP 2263
CP A+ C PSC + G + PS A C+C G V E K C P
Sbjct: 642 CPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAP 701
Query: 2264 -------RSQCGCKDAHGGSIPLGKSWVSS-------GCTEKCVCTGGAIQCGDFRC--P 2307
R C C D G LG+S++S+ C C GG + CG C P
Sbjct: 702 ALCPFPARGDC-CPDCDGCEY-LGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPP 759
Query: 2308 SGSHCQLTSDNSNSNC 2323
SH + S + C
Sbjct: 760 GCSHPLIPSGHCCPTC 775
Score = 41.2 bits (95), Expect = 0.015
Identities = 50/193 (25%), Positives = 61/193 (31%), Gaps = 33/193 (17%)
Query: 1748 PQGPFSQCHQVVPPQSSFASC----VHGQCGTKGDTTALCRSLQAYASLCA-QAGQAPAW 1802
P P H ++P +C HG G+T L L SLC Q G
Sbjct: 755 PCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGET--LPDPLDPTCSLCTCQEGSMRCQ 812
Query: 1803 RNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALP----CAESCECQKGHI-LS 1857
+ CP P S PC P +C S + E C CQ G +
Sbjct: 813 KKP--CPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCV 870
Query: 1858 GTSCVPL---------GQC-----GCTDPAGSYHPVGERWYTENTCTRLCTCS----VHN 1899
C PL G C GC G HP G RW ++ C C
Sbjct: 871 RLQCPPLPCKLQVTERGSCCPRCRGCL-AHGEEHPEGSRWVPPDSACSSCVCHEGVVTCA 929
Query: 1900 NITCFQSTCKPNQ 1912
I C S +P Q
Sbjct: 930 RIQCISSCAQPRQ 942
Score = 39.7 bits (91), Expect = 0.042
Identities = 37/137 (27%), Positives = 52/137 (37%), Gaps = 24/137 (17%)
Query: 2619 PGRPRGLRGPLRGRLRQHPRLCLQWHPEP---------PLADCGCTSNGIYYQLGSSFLT 2669
PG P + L G ++ R C P P P+ D GC NG ++ G +
Sbjct: 209 PGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCD-GCFLNGREHRSGEPVGS 267
Query: 2670 EDCSQRCTCASSRI----LLCEPFSCR-----AGEVCTLGNHTQGCFPESPCLQNPCQND 2720
D C CA+ + L C P CR G+ C + GC E Q Q
Sbjct: 268 GDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPV---CDGC--EYQGHQYQSQET 322
Query: 2721 GQCREQGATFTCECEVG 2737
+ +E+G C C+ G
Sbjct: 323 FRLQERGLCVRCSCQAG 339
Score = 39.3 bits (90), Expect = 0.055
Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 9/96 (9%)
Query: 1815 GSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCG--CTDP 1872
G +Y + PD C++ R A+ C + C + + L SC P G+C C
Sbjct: 142 GQTYGNGETFSPDACTTC---RCLTGAVQC-QGPSCSELNCLE--SCTPPGECCPICCTE 195
Query: 1873 AGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTC 1908
GS+ G+ W T R+C C + +I C Q C
Sbjct: 196 GGSHWEHGQEWTTPGDPCRICRC-LEGHIQCRQREC 230
Score = 37.0 bits (84), Expect = 0.28
Identities = 28/103 (27%), Positives = 40/103 (38%), Gaps = 17/103 (16%)
Query: 2645 PEPPLADC-GCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHT 2703
P+ L C GC+ NG Y G +F + C+ C C + + C+ G C+ N
Sbjct: 128 PQAHLPHCRGCSQNGQTYGNGETFSPDACT-TCRCLTGAV------QCQ-GPSCSELNCL 179
Query: 2704 QGCFPESPCLQNPCQNDGQCREQGATFT--------CECEVGY 2738
+ C P C C G E G +T C C G+
Sbjct: 180 ESCTPPGECCPICCTEGGSHWEHGQEWTTPGDPCRICRCLEGH 222
Score = 37.0 bits (84), Expect = 0.28
Identities = 59/263 (22%), Positives = 87/263 (33%), Gaps = 49/263 (18%)
Query: 2105 PSCQSLLVDEQQIPA-EQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFL 2163
PSC L ++ + E+ +P+ C CE AP +R D P
Sbjct: 657 PSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCP-- 714
Query: 2164 VDCANTLCEF-GGLYQA------------LCQALQAFGATCQSQGLKPPLWRNSSFCPLE 2210
DC CE+ G Y + LC L F TC + +PP +
Sbjct: 715 -DCDG--CEYLGESYLSNQEFPDPREPCNLCTCLGGF-VTCGRRPCEPPGCSH------- 763
Query: 2211 CPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSAC---AEGCICQPGYVLSEDKCVPRSQC 2267
P S +C P+C + G +P C CQ G + + K P + C
Sbjct: 764 -PLIPS-GHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALC 821
Query: 2268 GCKDAHGGSIPLGKSWVS--------------SGCTEKCVCTGGAIQCGDFRCPSGSHCQ 2313
P+ S +S +G E C C G + C +CP C+
Sbjct: 822 PHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPP-LPCK 880
Query: 2314 LTSDNSNSNCVSDKSEQCSVYGD 2336
L S C + C +G+
Sbjct: 881 LQVTERGSCC--PRCRGCLAHGE 901
Score = 35.4 bits (80), Expect = 0.80
Identities = 27/90 (30%), Positives = 34/90 (37%), Gaps = 14/90 (15%)
Query: 2248 CICQPGYVLSEDKCVP----------RSQCGCKDAHGGSIPLGKSWVSSG--CTEKCVCT 2295
C CQ G V E++ P R C + G G W G CT CVC
Sbjct: 334 CSCQAGEVSCEEQECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTA-CVCQ 392
Query: 2296 GGAIQCGDFRCPSGSHCQLTSDNSNSNCVS 2325
G +CG CP + CQ + + C S
Sbjct: 393 DGVPKCGAVLCPP-APCQHPTQPPGACCPS 421
Score = 35.0 bits (79), Expect = 1.0
Identities = 29/89 (32%), Positives = 34/89 (38%), Gaps = 20/89 (22%)
Query: 1045 PPNARYESCACPAS-CKSPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNNDYYE 1103
P AR+E AC A C+ CGP HC C N Y
Sbjct: 104 PEGARWEPDACTACVCQDGAAHCGPQAHLP------------HCR-----GCSQNGQTYG 146
Query: 1104 PGAEWFSPNCTEHCRCWPGSRVECQISQC 1132
G E FSP+ CRC G+ V+CQ C
Sbjct: 147 NG-ETFSPDACTTCRCLTGA-VQCQGPSC 173
Score = 32.7 bits (73), Expect = 5.2
Identities = 32/136 (23%), Positives = 45/136 (33%), Gaps = 43/136 (31%)
Query: 1809 PMRCPPGSSYSPCSSPCPDTCSSINNPRDC----------------PKALPCAESCECQK 1852
P CP +PC+ P P TC P DC P C C
Sbjct: 518 PRPCPR----APCAHPLPGTCC----PNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLS 569
Query: 1853 GHI-LSGTSCVPL---------GQC--------GCTDPAGSYHPVGERWYTENTCTRLCT 1894
G++ CVPL G+C GC P ++ E + R C
Sbjct: 570 GNVQCLARRCVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCL 629
Query: 1895 CSVHNNITCFQSTCKP 1910
C + +++C + C P
Sbjct: 630 C-LDGSVSCQRLPCPP 644
Score = 32.0 bits (71), Expect = 8.8
Identities = 30/108 (27%), Positives = 42/108 (38%), Gaps = 17/108 (15%)
Query: 1426 CPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFV---------LSGLE-CIP 1475
C P + C + G F D C C C G V L+ LE C P
Sbjct: 126 CGPQAHLPHCRGCSQNGQTYGNGETFSPDACT-TCRCLTGAVQCQGPSCSELNCLESCTP 184
Query: 1476 RSQCG--CLHPAGSYFKVGERWYKPG--CKELCVCESNNRIRCQPWRC 1519
+C C GS+++ G+ W PG C+ +C C I+C+ C
Sbjct: 185 PGECCPICCTEGGSHWEHGQEWTTPGDPCR-ICRC-LEGHIQCRQREC 230
>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
Length = 2639
Score = 213 bits (542), Expect = 2e-54
Identities = 293/1094 (26%), Positives = 404/1094 (36%), Gaps = 104/1094 (9%)
Query: 521 VVAMGFIL---INPGTCPVKVLPELPPVSPVSSTGPSE---TTGLTENPTISTKKPTVSI 574
V+ M F L IN C P + + P+ TT +T PT ++ + T
Sbjct: 1278 VIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPT 1337
Query: 575 EKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPT 634
+ TT PT PT P I+T P+ P T P T +T PT
Sbjct: 1338 PITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1396
Query: 635 IPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTE 694
P+ T P+ P I+T PT PT TTT I T PT P+ T+
Sbjct: 1397 -PTGTQT-PTSTP-ITTTTTVTPTPTPTGTQTPTTTP-----ITTTTTVTPTPTPT-GTQ 1447
Query: 695 KPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTI 754
PT + T ST PT +P PT P T T +P T T PT T T+
Sbjct: 1448 APTPTAITTT-STVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTV 1506
Query: 755 SPEKPTTPTEKPTISPEKLT---IPTEKPT---------IPTEKPTIPTEKPTISTEEPT 802
+P T T+ PT +P T PT PT I T PT PT + T
Sbjct: 1507 TPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTT 1566
Query: 803 TPTEETTISTEKPS-IPMEKPT--LPTEETTTSVEETTISTEKLTI-PMEKPTISTEKPT 858
TP TT T P+ + PT L T TT + T ST+ T+ P+ T T PT
Sbjct: 1567 TPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPT 1626
Query: 859 -IPTEKPTISPEKLT---IPTEKLTI-----PTEKPTIPIEETTIST---EKLTIPTEKP 906
T+ PT+ P T PT T PT T PI E T S E T T +
Sbjct: 1627 PTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRS 1686
Query: 907 TISP--EKPT-ISTEKPTI---PTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTE 960
T SP E T +ST P I T P+ PT TT S P T SP PT
Sbjct: 1687 TSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPP--GTPTR 1744
Query: 961 KPTI-STEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSP 1019
T S+ PT T + T + PT T + T LR P+PS L +
Sbjct: 1745 GTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLR-PYPSSVLI-CCVLNDTY 1802
Query: 1020 HAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPG 1079
+AP + + G T + + C + + +CP+ +P P+ P P
Sbjct: 1803 YAPGEEVYNGTYGDTCYFVNCSLSC--TLEFYNWSCPS---TPSPTPTPSKSTPTPSKPS 1857
Query: 1080 FLFS-DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVC 1138
S + C F + + W+ +C C + VE +C +
Sbjct: 1858 STPSKPTPGTKPPECPDF--DPPRQENETWWLCDCF-MATCKYNNTVEIVKVECEPPPMP 1914
Query: 1139 QLKNGQYG---------CHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNS 1189
NG C + C +GDPHYVTFDG ++ + G CTY+L + S
Sbjct: 1915 TCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPS 1974
Query: 1190 TDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTL-------VGGQQVTLPA 1242
D F + VSC + + E+ L+K + V Q V LP
Sbjct: 1975 VDNFGVYIDNYHCDPNDKVSC-PRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALP- 2032
Query: 1243 IPSKGVFLGASG-RFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDND 1301
G+ + SG +V E G+ V ++G + G CG + +D
Sbjct: 2033 YKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDD 2092
Query: 1302 HLKLDGSPAGDKEELGNSWQTDQDEDQEC------QKYQVVNSPSCDSSLQSSMSGPG-F 1354
+ G + E + W + C K V P + P
Sbjct: 2093 CILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL 2152
Query: 1355 CGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVK 1414
C + D+ F C V ++D+C+ D C G L C + C +
Sbjct: 2153 CQLIKDS--LFAQCHALVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQNICLD 2209
Query: 1415 PWREPH-FCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFV--LSGL 1471
H C + CP + +Y C TC S S + VE C C G + G
Sbjct: 2210 WRNHTHGACLVECPSHREYQACGPAEEPTCKSS-SSQQNNTVLVEGCFCPEGTMNYAPGF 2268
Query: 1472 ECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVC-ESNNRIRCQPWRCRAQEFCG-QQD 1529
+ ++ CGC+ P + GE ++ CK CVC E + I CQP RC + +D
Sbjct: 2269 DVCVKT-CGCVGPDNVPREFGEH-FEFDCKN-CVCLEGGSGIICQPKRCSQKPVTHCVED 2325
Query: 1530 GIY-GCHAQGAATC 1542
G Y A TC
Sbjct: 2326 GTYLATEVNPADTC 2339
Score = 166 bits (421), Expect = 2e-40
Identities = 201/851 (23%), Positives = 318/851 (37%), Gaps = 159/851 (18%)
Query: 1561 MGTCTYV-LTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKV 1619
M TC+++ ++ C D F + + + K +V VF S V
Sbjct: 314 MDTCSHLEVSSLCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNVVVFKSDGS------V 367
Query: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVE--VTVPSSYGGQLC 1677
+LN +V LP A V R SS +++ G++++ + +++ VT+ + GQ+
Sbjct: 368 LLNELQVNLPHVTASFSV-FRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQ 426
Query: 1678 GLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPS-SCQENSMAD 1736
GLCGN+N DD + WK S + S + + + A+
Sbjct: 427 GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAE 486
Query: 1737 AWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796
W C++L + PF +CH V P + C + C + + LC +L +YA C
Sbjct: 487 HW---CSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAK 543
Query: 1797 G-QAPAWRNRTFCPM---RCPPGSSYSPCSSPCPDTCSSINN----------PRD---CP 1839
G WR C CP + + C TC S++ P D CP
Sbjct: 544 GVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCP 602
Query: 1840 ---------KALPCA---------------------ESCECQKGHI------LSGTSCV- 1862
+ +P A E C C+ G + L G SC
Sbjct: 603 DHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTA 662
Query: 1863 PLGQCGCTD-----------------PAGSYH---------PVGERWYTENTCT--RLCT 1894
P C++ AG YH P G C + C
Sbjct: 663 PKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECP 722
Query: 1895 CSVHNN----------ITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDG 1944
C VHNN + C TCK + W +A G C + G HY++FDG
Sbjct: 723 C-VHNNDLYSSGAKIKVDCNTCTCKRGR--WVCT-----QAVCHGTCSIYGSGHYITFDG 774
Query: 1945 SNHSIPDACTLVLVK-VCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQ 2003
+ C+ V V+ C +L F I ++ G T + I + ++ L+
Sbjct: 775 KYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPC-GTTGVTCSKAIKIFMGRTELKLE 833
Query: 2004 KGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYG 2063
HRV+I + + + Y +V G+ V +D + I++ +Y G
Sbjct: 834 DKHRVVIQRDE------GHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKG 887
Query: 2064 KVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQE 2123
VCG+CGNF+ ++ V +S+ +F NSWK+ P+C +
Sbjct: 888 TVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---PTCPDV-----------ST 933
Query: 2124 NPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCA--NTLCEFGGLYQALC 2181
NP R EK + L++ V++ C S++D PF C + C+ GG + C
Sbjct: 934 NPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFC 993
Query: 2182 QALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS-------SYTNCLPSCSPSCWDLDGR 2234
A+ ++ C +G WR CP+ C Y+ Y C +C ++G
Sbjct: 994 SAVASYAQECTKEG-ACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGI 1052
Query: 2235 CEGAKVPSACAEGCI--C---QPGYVLSEDKCVPRSQCGC--KDAHGGSIPLGKSWVSSG 2287
V + EGC C +P Y KCV +CGC +D H P G S +
Sbjct: 1053 HSNISV--SYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTH---YPPGASVPTEE 1107
Query: 2288 CTEKCVCTGGA 2298
+ CVCT +
Sbjct: 1108 TCKSCVCTNSS 1118
Score = 165 bits (417), Expect = 7e-40
Identities = 126/477 (26%), Positives = 199/477 (41%), Gaps = 79/477 (16%)
Query: 1070 CREGCVCNPGFLFSDNH--CIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVEC 1127
C GCVC G L D C+ C C +NND Y GA+ +V+C
Sbjct: 697 CVSGCVCPDG-LMDDGRGGCVVEKECPCVHNNDLYSSGAK---------------IKVDC 740
Query: 1128 QISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C 1186
C K G++ C TC +YG HY+TFDG+++ F G C+Y+ Q C
Sbjct: 741 N--------TCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYC 792
Query: 1187 G-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPS 1245
G NS+ F + +N G GV+C + + + + + L R ++ + A +
Sbjct: 793 GQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTT 852
Query: 1246 KGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKL 1305
+ V G+++ +++ G+ V WD +++ ++ +Y G +CGLCGN+D S+ND
Sbjct: 853 REV-----GQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTR 907
Query: 1306 DGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPF 1365
D + + GNSW+ E C N C + C L + F
Sbjct: 908 DHMVVSSELDFGNSWK----EAPTCPDVS-TNPEPCSLNPHRRSWAEKQCSILKSS--VF 960
Query: 1366 ETCLLHVKAASFFDSCMLDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCP 1423
C V F+++C+ D C G C+ +++ C G V WR P CP
Sbjct: 961 SICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCP 1019
Query: 1424 MAC----PPNS---KYSLCAKPCPDTC------HSGFSGMF---CSDRCVEACECNPGFV 1467
+ C PP+ Y C +TC HS S + C RC + P +
Sbjct: 1020 IFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKD---RPIYE 1076
Query: 1468 LSGLECIPRSQCGCLHPAGSYFKVGERWYKPG--------CKELCVCESNNRIRCQP 1516
+C+ +CGC V + Y PG CK CVC +++++ C+P
Sbjct: 1077 EDLKKCVTADKCGCY--------VEDTHYPPGASVPTEETCKS-CVCTNSSQVVCRP 1124
Score = 164 bits (414), Expect = 1e-39
Identities = 139/497 (27%), Positives = 206/497 (41%), Gaps = 81/497 (16%)
Query: 1436 AKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLE-CIPRSQCGCLHPAGSYFKVGER 1494
+KP +C + +G + ++ CV C C G + G C+ +C C+H
Sbjct: 678 SKPRALSCQTLAAGYYHTE-CVSGCVCPDGLMDDGRGGCVVEKECPCVH--------NND 728
Query: 1495 WYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFD 1554
Y G K C N C+ R + C Q CH TC+ G HY+TFD
Sbjct: 729 LYSSGAKIKVDC---NTCTCK----RGRWVCTQAV----CHG----TCSIYGSGHYITFD 773
Query: 1555 GALHHFMGTCTYVLTRP-CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISL 1613
G + F G C+YV + C S F + N G V+ KA+ + + + L
Sbjct: 774 GKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCG-TTGVTCSKAIKIFMGRTELKL 832
Query: 1614 LRGCKVMLN---GHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPS 1670
+V++ GH VA T R +++ ++ G+ V +D V + +
Sbjct: 833 EDKHRVVIQRDEGHHVAY---------TTREVGQYLVVESSTGIIVIWDKRTTVFIKLAP 883
Query: 1671 SYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQ 1730
SY G +CGLCGN+++ S +D D + + G +WK P C V P C
Sbjct: 884 SYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWK----EAPTCPDVSTNPEPCS 939
Query: 1731 ENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG--TKGDTTALCRSLQ 1787
N +W K C+IL FS CH V P+ + +CVH C T GD C ++
Sbjct: 940 LNPHRRSWAEKQCSIL--KSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVA 997
Query: 1788 AYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSPCPDTCSSINN------ 1834
+YA C + G WR CP+ C PP Y PC + +TC +IN
Sbjct: 998 SYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNIS 1057
Query: 1835 --------PRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTE 1886
PR CPK P E + +K CV +CGC +++P G TE
Sbjct: 1058 VSYLEGCYPR-CPKDRPIYEE-DLKK--------CVTADKCGCY-VEDTHYPPGASVPTE 1106
Query: 1887 NTCTRLCTCSVHNNITC 1903
TC + C C+ + + C
Sbjct: 1107 ETC-KSCVCTNSSQVVC 1122
Score = 128 bits (321), Expect = 9e-29
Identities = 179/775 (23%), Positives = 276/775 (35%), Gaps = 163/775 (21%)
Query: 2000 VTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGV--QVKFDGNHLLEIEI 2057
V + VL+N QV LP ++ V + SS + +V++ IGV QV+ L + +
Sbjct: 359 VVFKSDGSVLLNELQVNLPHVTASFSV-FRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTL 417
Query: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQI 2117
G+V G+CGNFN E D+ S V + + F N+WK + SC L
Sbjct: 418 DQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS---SCHDKL------ 468
Query: 2118 PAEQQENP-SGNCRAADLRRAREKCEAALRAPV-WAQCASRIDLTPFLVDCANTLCEFGG 2175
+ ++P S N +A+ A C + + +C S +D + C C
Sbjct: 469 --DWLDDPCSLNIESANY--AEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQN 524
Query: 2176 LYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLE---CPAYSSYTNCLPSCSPSCWDL- 2231
LC AL ++ C ++G+ WR C + CP + L +C +C L
Sbjct: 525 NEDCLCAALSSYARACTAKGVMLWGWREH-VCNKDVGSCPNSQVFLYNLTTCQQTCRSLS 583
Query: 2232 --DGRCEGAKVPSACAEGCICQPGYVLSED-KCVP----------------------RSQ 2266
D C P +GC C L E +CVP +
Sbjct: 584 EADSHCLEGFAP---VDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEER 640
Query: 2267 CGCKD----------------------------AHGGSIP-------LGKSWVSSGCTEK 2291
C C+D A S P L + + C
Sbjct: 641 CVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSG 700
Query: 2292 CVCTGGAIQCGDFRCPSGSHCQLTSDNSN-----------SNCVSDKSE----------Q 2330
CVC G + G C C +N + C +
Sbjct: 701 CVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGT 760
Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
CS+YG Y+TFDG Y G +YV ++ + + N + + + +
Sbjct: 761 CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITEN-VPCGTTGVTCSK 819
Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLW--GQRLYLVTDFELVVSFGG 2448
I G + + LE + ++ + H+ T GQ L + + ++V +
Sbjct: 820 AIKIFMG---RTELKLE---DKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDK 873
Query: 2449 RKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRF 2508
R I L Y+G V GLCGN+D ND + + FGNSW
Sbjct: 874 RTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSW----------- 922
Query: 2509 PRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEP 2568
+ P + + T + +P + S + + C +L F+ CH V P+P
Sbjct: 923 -KEAPTCPD-------VSTNPEPCSLNPHR-RSWAEKQCSIL--KSSVFSICHSKVDPKP 971
Query: 2569 FQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRPRGLRGP 2628
F E CV D CS D E C ++ + + ++ P LC P
Sbjct: 972 FYEACVHDSCSC-DTGGDCECFCSAVASYAQECTKEGACVFWRTPD-LC----------P 1019
Query: 2629 LRGRLRQHPRLCLQWHPEPPLADCG------C-TSNGIYYQLGSSFLTEDCSQRC 2676
+ P C +WH EP CG C T NGI+ + S+L E C RC
Sbjct: 1020 IFCDYYNPPHEC-EWHYEP----CGNRSFETCRTINGIHSNISVSYL-EGCYPRC 1068
Score = 128 bits (321), Expect = 9e-29
Identities = 119/455 (26%), Positives = 171/455 (37%), Gaps = 52/455 (11%)
Query: 1493 ERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIY--------GC--HAQGAATC 1542
E W+ C + C+ NN + C +G+ GC H + C
Sbjct: 1883 ETWWLCDCF-MATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYC 1941
Query: 1543 TASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFV--------------VSATNE 1588
T GDPHY+TFDG + + G CTYVL S S D++ V T
Sbjct: 1942 TGWGDPHYVTFDGLYYSYQGNCTYVLVEEI-SPSVDNFGVYIDNYHCDPNDKVSCPRTLI 2000
Query: 1589 NRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLL 1648
R EV IK VH+ + +V +N VALP + G + N V+
Sbjct: 2001 VRHETQEV-LIKTVHMMPMQV--------QVQVNRQAVALP-YKKYGLEVYQSGINYVVD 2050
Query: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708
G+ V Y+G +G G CG N + DD + P ++ +
Sbjct: 2051 IPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQ 2110
Query: 1709 WKLPESSEPGC---FLVGGKPSSCQENSMADAWNKNCA----ILINPQGPFSQCHQVVPP 1761
W + + S+P C +P+ +K+C + F+QCH +VPP
Sbjct: 2111 WLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPP 2170
Query: 1762 QSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTF--CPMRCPPGSSYS 1819
Q + +CV C G + C SLQAYA+LCAQ WRN T C + CP Y
Sbjct: 2171 QHYYDACVFDSCFMPGSSLE-CASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQ 2229
Query: 1820 PCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSC-VPLGQCGCTDPAGSYHP 1878
C TC S ++ ++ E C C +G + V + CGC P
Sbjct: 2230 ACGPAEEPTCKSSSSQQN---NTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPRE 2286
Query: 1879 VGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQI 1913
GE + E C + I C C +
Sbjct: 2287 FGEHF--EFDCKNCVCLEGGSGIICQPKRCSQKPV 2319
Score = 111 bits (277), Expect = 1e-23
Identities = 144/566 (25%), Positives = 198/566 (34%), Gaps = 67/566 (11%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 1326 PTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 1382
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T +T +T T++ + P+ +TT P
Sbjct: 1383 TPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1442
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P T P T +T PT + P+
Sbjct: 1443 PT-GTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAIT 1501
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
T +T PT T+ PT+ TTT++ PT + PT P T T++ T
Sbjct: 1502 TTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQT-PTPTPISTTT--TVTPTPTP 1558
Query: 705 ISTEKPTISPEKPTI---PTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTT 761
T+ PT +P T PT PT +T+ TT T PT + K T TT
Sbjct: 1559 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTT 1618
Query: 762 PTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEK 821
T T +P PT P I T PT PT + P T T I+ S P +
Sbjct: 1619 TTVTATPTPTGTQTPTMIP-ISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPE 1677
Query: 822 PTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIP 881
+ P +TS T +T T+P ST P+ PT T S P T
Sbjct: 1678 SSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTT-- 1735
Query: 882 TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTI------------ 929
T P P TT + P+ T+ + T PT P P+I
Sbjct: 1736 TSPPGTPTRGTTTGSSSAPTPS---TVQTTTTSAWTPTPT-PLSTPSIIRTTGLRPYPSS 1791
Query: 930 -------------PTEETTISTE---------KLTIPTEKPTISPEKLTIPTEKPTISTE 967
P EE T L+ E S PT P+ ST
Sbjct: 1792 VLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTP 1851
Query: 968 KPTIPTEKLTIPTEKPTIPTEKPTIP 993
P+ P+ KPT T+ P P
Sbjct: 1852 TPSKPSST----PSKPTPGTKPPECP 1873
Score = 105 bits (261), Expect = 8e-22
Identities = 96/343 (27%), Positives = 136/343 (39%), Gaps = 42/343 (12%)
Query: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKE-E 1980
R R G VC G HY +FDG P C C + +K A H K
Sbjct: 28 RTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGS-----YKEFAVHLKRGP 82
Query: 1981 GGTEA-FRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNI 2039
G EA + + + I D + L + H ++N V+ P S PG+ ++ S Y+ V
Sbjct: 83 GQAEAPAGVESILLTIKDDTIYLTR-HLAVLNGAVVSTPHYS--PGLLIEKSDAYTKVYS 139
Query: 2040 KIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWK 2099
+ G+ + ++ L +E+ T + CG+CG++N + + SD V S EF N K
Sbjct: 140 RAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL-SDGVLFSPLEFGNMQK 198
Query: 2100 DKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDL 2159
D C+ +E+ PA E+ R +CE L A +A C + L
Sbjct: 199 INQPDVVCED--PEEEVAPASCSEH-------------RAECERLLTAEAFADCQDLVPL 243
Query: 2160 TPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRN-----SSFCPLECPAY 2214
P+L C C G +C + F C G +P WR S CP
Sbjct: 244 EPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGN 303
Query: 2215 SSYTNCLPSCSPSCWDLDGRCEGAKVPSACAE----GCICQPG 2253
Y L S SP C D C +V S C E GC C G
Sbjct: 304 LVY---LESGSP-CMD---TCSHLEVSSLCEEHRMDGCFCPEG 339
Score = 103 bits (258), Expect = 2e-21
Identities = 83/322 (25%), Positives = 130/322 (40%), Gaps = 23/322 (7%)
Query: 1152 GTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCL 1211
G C +G+ HY TFDG F F G C Y A C S F V K E + +
Sbjct: 33 GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEF-AVHLKRGPGQAEAPAGV 91
Query: 1212 SKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDG 1271
+ +T+ + T+ L + ++ G V+ P S G+ + S + ++ + GL + W+
Sbjct: 92 ESILLTIKDDTIYLTR-HLAVLNGAVVSTPHY-SPGLLIEKSDAYTKVYSRAGLTLMWNR 149
Query: 1272 DQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDG---SPAGDKEELGNSWQTDQDEDQ 1328
+ L + + + + CGLCG+Y+G DG SP E GN + +Q D
Sbjct: 150 EDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL----EFGNMQKINQ-PDV 204
Query: 1329 ECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGF 1388
C+ + +P+ S ++ C RL+ T F C V + +C D C
Sbjct: 205 VCEDPEEEVAPASCSEHRAE------CERLL-TAEAFADCQDLVPLEPYLRACQQDRCRC 257
Query: 1389 QGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHF-----CPMACPPNSKYSLCAKPCPDTC 1443
G +C+ ++ + C AG WR CP N Y PC DTC
Sbjct: 258 PGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTC 317
Query: 1444 HSGFSGMFCSDRCVEACECNPG 1465
C + ++ C C G
Sbjct: 318 SHLEVSSLCEEHRMDGCFCPEG 339
Score = 102 bits (255), Expect = 4e-21
Identities = 90/358 (25%), Positives = 145/358 (40%), Gaps = 31/358 (8%)
Query: 1185 PCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLV----------G 1234
PC + T V++ EE +G C LP++ V L ++ +V
Sbjct: 312 PCMD-TCSHLEVSSLCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNVVVFKSDGSVLLN 370
Query: 1235 GQQVTLPAIPSKGVFLGASGRFVELQTEFGLR--VRWDGDQQLYVTVSSTYSGKLCGLCG 1292
QV LP + + S + + G+R V+ QL+VT+ G++ GLCG
Sbjct: 371 ELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCG 430
Query: 1293 NYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQ-KYQVVNSPSCDSSLQSSMSG 1351
N++G +D G N+W+ C K ++ P C +++S+
Sbjct: 431 NFNGLEGDDFKTASGLVEATGAGFANTWKAQSS----CHDKLDWLDDP-CSLNIESANYA 485
Query: 1352 PGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGH 1411
+C L T PF C V A ++ C D C Q + LC +S+ C G
Sbjct: 486 EHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGV 545
Query: 1412 AVKPWREPHFCPM---ACPPNSKYSLCAKPCPDTCHS-GFSGMFCSD--RCVEACEC-NP 1464
+ WRE H C +CP + + C TC S + C + V+ C C +
Sbjct: 546 MLWGWRE-HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDH 604
Query: 1465 GFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQ 1522
F+ C+P ++C C H G Y + G+ + +E CVC + R+ C+ R Q
Sbjct: 605 TFLDEKGRCVPLAKCSCYH-RGLYLEAGDVVVRQ--EERCVCR-DGRLHCRQIRLIGQ 658
Score = 100 bits (250), Expect = 2e-20
Identities = 113/488 (23%), Positives = 184/488 (37%), Gaps = 68/488 (13%)
Query: 1892 LCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLP----------GESHYVS 1941
+ TC +N + + C+P + +GL R C G+ HYV+
Sbjct: 1892 MATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVT 1951
Query: 1942 FDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKH----EKEEGGTEAFRLHEVYIDIYD 1997
FDG +S CT VLV+ P++ I H +K HE +
Sbjct: 1952 FDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIK 2011
Query: 1998 AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNI-KIGVQVKFDGNHLLEIE 2056
+ +V +N + V LP G+ V S I +V+I ++GV V ++G +
Sbjct: 2012 TVHMMPMQVQVQVNRQAVALPYKKY--GLEVYQSGINYVVDIPELGVLVSYNGLS-FSVR 2068
Query: 2057 IPTTYYG-KVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKD-IDPSCQSLLVDE 2114
+P +G G CG + D+ ++PS E+ ++ + W D P C
Sbjct: 2069 LPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTT 2128
Query: 2115 QQ----IPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTL 2170
++ +P + P +C + L C+ ++ ++AQC + + + C
Sbjct: 2129 KRPAVTVPGGGKTTPHKDCTPSPL------CQ-LIKDSLFAQCHALVPPQHYYDACVFDS 2181
Query: 2171 CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSF--CPLECPAYSSYTNCLPSCSPSC 2228
C G C +LQA+ A C Q + WRN + C +ECP++ Y C P+ P+C
Sbjct: 2182 CFMPG-SSLECASLQAYAALCAQQNICLD-WRNHTHGACLVECPSHREYQACGPAEEPTC 2239
Query: 2229 WDLDGRCEGAKVPSACAEGCICQPG---YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVS 2285
+ + EGC C G Y D CV CGC G+ +
Sbjct: 2240 KSSSSQQNN----TVLVEGCFCPEGTMNYAPGFDVCV--KTCGCVGPDNVPREFGEHFEF 2293
Query: 2286 SGCTEKCVCT--GGAIQCGDFRC--------------------PSGSHCQLTSDNSNSNC 2323
+ CVC G I C RC P+ + C +T N++
Sbjct: 2294 D--CKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSL 2351
Query: 2324 VSDKSEQC 2331
+K C
Sbjct: 2352 CKEKPSVC 2359
Score = 99.4 bits (246), Expect = 5e-20
Identities = 132/525 (25%), Positives = 187/525 (35%), Gaps = 79/525 (15%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533
P P + + P T+VT P+G Q P I + T + P T
Sbjct: 1372 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTST---PITTTTTVTPTPTPTGTQTPTT 1428
Query: 534 CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590
P+ + P + T T +T T++ + P+ +TT P
Sbjct: 1429 TPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1488
Query: 591 PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647
PT T+ PT I+T P+ P + P T +T PT + P+
Sbjct: 1489 PT-GTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPIS 1547
Query: 648 TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPT--EKPS---IPTEKPSIPTEKPT-- 697
T +T PT T+ PTT TTT++ PT + P+ I T PT PT
Sbjct: 1548 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTST 1607
Query: 698 -------ISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTE 750
I+ T+ +T PT + IP T T T + PT T P
Sbjct: 1608 KSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIA 1667
Query: 751 KPTIS---PEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEE 807
+ T S PE T T + T SP TE T+ + T+P ST P+TPT
Sbjct: 1668 ELTTSNPPPESSTPQTSRSTSSPL-----TESTTLLS---TLPPAIEMTSTAPPSTPTAP 1719
Query: 808 TTIS-----TEKPSIPMEKPTLPTEETTT---------SVEETTISTEKLT-IPMEKPTI 852
TT S + PS P PT TTT +V+ TT S T P+ P+I
Sbjct: 1720 TTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSI 1779
Query: 853 STEKPTIPTEKPT----ISPEKLTIPTEKL------------------TIPTEKPTIPIE 890
P + + P E++ T+ + P
Sbjct: 1780 IRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPST 1839
Query: 891 ETTISTEKLTIPT-EKPTISPEKPTISTEKPTIPTEKPTIPTEET 934
+ T + PT KP+ +P KPT T+ P P P ET
Sbjct: 1840 PSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENET 1884
Score = 94.0 bits (232), Expect = 2e-18
Identities = 82/327 (25%), Positives = 132/327 (40%), Gaps = 31/327 (9%)
Query: 1538 GAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVS 1597
G C+ G+ HY TFDG + F G C Y C R F V G +
Sbjct: 33 GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVH-LKRGPGQAEAPA 89
Query: 1598 YIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVR 1657
++++ +T+ D +I L R V LNG V+ P + + I S +Y+ GL +
Sbjct: 90 GVESILLTIKDDTIYLTRHLAV-LNGAVVSTPHY--SPGLLIEKSDAYTKVYSRAGLTLM 146
Query: 1658 YDGSHLVEVTVPSSYGGQLCGLCGNYN-----NNSLDDNLRPDRKLAGDSMQLGAAWKLP 1712
++ + + + + + CGLCG+YN + L D + G+ ++ +
Sbjct: 147 WNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVC 206
Query: 1713 ESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQ 1772
E E P+SC E+ C L+ + F+ C +VP + +C +
Sbjct: 207 EDPEEEV-----APASCSEH------RAECERLLTAEA-FADCQDLVPLEPYLRACQQDR 254
Query: 1773 CGTKGDTTALCRSLQAYASLCAQAGQAPA-WRNRTF-----CPMRCPPGSSYSPCSSPCP 1826
C G T +C ++ ++ C+ AG P WR T CP Y SPC
Sbjct: 255 CRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCM 314
Query: 1827 DTCSSINNPRDCPKALPCAESCECQKG 1853
DTCS + C + + C C +G
Sbjct: 315 DTCSHLEVSSLCEEHR--MDGCFCPEG 339
Score = 84.0 bits (206), Expect = 2e-15
Identities = 69/257 (26%), Positives = 113/257 (43%), Gaps = 24/257 (9%)
Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIK----TVDVLPEGVEPLLVEGRNKMDPPRSSI 2386
C+ +GDP Y+TFDG Y QG TYVL++ +VD ++ + +K+ PR+ I
Sbjct: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 2000
Query: 2387 FLQE----VITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYL-VTDFE 2441
E +I TV+ +Q+Q + VN Q +A+PY+ L V G + + +
Sbjct: 2001 VRHETQEVLIKTVHMMPMQVQ----VQVNRQAVALPYK-KYGLEVYQSGINYVVDIPELG 2055
Query: 2442 LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKT 2501
++VS+ G +V + G CG +D +LPSG + N + W V
Sbjct: 2056 VLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLV-N 2114
Query: 2502 EDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACH 2561
+ + P + + G +C+P L C+++ D FA CH
Sbjct: 2115 DPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL-------CQLIKD--SLFAQCH 2165
Query: 2562 QTVAPEPFQEHCVLDLC 2578
V P+ + + CV D C
Sbjct: 2166 ALVPPQHYYDACVFDSC 2182
Score = 60.1 bits (144), Expect = 3e-08
Identities = 99/375 (26%), Positives = 134/375 (35%), Gaps = 75/375 (20%)
Query: 477 PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQ-LIFKGIQGSNTASVVAMGFILINPG 532
P P + + P T+VT P+G Q P LI + T + + + P
Sbjct: 1556 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPI 1615
Query: 533 TC-------PVKVLPELPPVSPVSSTG-----PSETTGLTENPTISTKKPTVSIEKPSVT 580
T P + P + P+S+T P+ TTG T PT ++ P + T
Sbjct: 1616 TTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAEL-----T 1670
Query: 581 TEKPTVPKEKPTIPTEKPTIS--TEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSE 638
T P P E T T + T S TE T+ S P T P PT PT S
Sbjct: 1671 TSNP--PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTA----PTTTSG 1724
Query: 639 KPTIPSEKPTISTEKPTVPTEEPTT-----PT----EETTTSMEEPV-IPTEKPSI---- 684
T+ S P+ +T P PT TT PT + TTTS P P PSI
Sbjct: 1725 GHTL-SPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTT 1783
Query: 685 ---------------------PTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEK 723
P E+ T T +S + P+ P+
Sbjct: 1784 GLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPT 1843
Query: 724 PTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPT-------ISPEKLTIP 776
PT KST +P KP++ KPT P KP P+ E T ++ K
Sbjct: 1844 PT--PSKSTPTPSKPSSTPSKPT-PGTKPPECPDFDPPRQENETWWLCDCFMATCKYNNT 1900
Query: 777 TEKPTIPTEKPTIPT 791
E + E P +PT
Sbjct: 1901 VEIVKVECEPPPMPT 1915
Score = 43.1 bits (100), Expect = 0.004
Identities = 52/249 (20%), Positives = 90/249 (36%), Gaps = 31/249 (12%)
Query: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
CS +G+ Y TFDG +R G Y + L G + + P ++
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAG---VES 93
Query: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVP-YRPNEHLRVTLWGQRLYLVTDFELVVSFGGR 2449
++ T+ + L L V+N ++ P Y P + + ++Y + L + +
Sbjct: 94 ILLTIKDDTIYLTRHL-AVLNGAVVSTPHYSPGLLIEKSDAYTKVY--SRAGLTLMWNRE 150
Query: 2450 KNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFP 2509
++ L + + GLCG+Y+ + L G L L FGN ++ D + P
Sbjct: 151 DALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPDVVCEDP 209
Query: 2510 RAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPF 2569
E +P + + + R+L FA C V EP+
Sbjct: 210 E---------------------EEVAPASCSEHRAECERLLT--AEAFADCQDLVPLEPY 246
Query: 2570 QEHCVLDLC 2578
C D C
Sbjct: 247 LRACQQDRC 255
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 207 bits (527), Expect = 1e-52
Identities = 192/731 (26%), Positives = 298/731 (40%), Gaps = 69/731 (9%)
Query: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVY 1215
C +G H+ TFD + F G C YI A C ++ P F V + G +S++
Sbjct: 45 CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAF-PTFSVQLRRGPDGS-----ISRII 98
Query: 1216 VTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFL---GASGRFVELQTEFGLRVRWDGD 1272
V L S VT+ + ++ ++LP S G+ + G S R V Q E L V W D
Sbjct: 99 VELGASVVTVSEAIISVKDIGVISLP-YTSNGLQITPFGQSVRLVAKQLELELEVVWGPD 157
Query: 1273 QQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQK 1332
L V V Y G++CGLCGN+DG N+ + +G E + D+ E
Sbjct: 158 SHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFL---EPHKFAALQKLDDPGEICT 214
Query: 1333 YQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQ--G 1390
+Q + S + + + C +L+ P C V F SC D+ G
Sbjct: 215 FQDIPSTHVRQAQHARI-----CTQLLTLVAP--EC--SVSKEPFVLSCQADVAAAPQPG 265
Query: 1391 LQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMA-CPPNSKYSLCAKPCPDTCHSGFSG 1449
Q+ C +S + C G V+ WR P C + CP N Y C C TC +
Sbjct: 266 PQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQHS 325
Query: 1450 MFCSDRCVEACECNPGFVLSGLE----CIPRSQCGC-LHPAGSYFKVGERWYKPGCKELC 1504
CS C C C G VL+ L C+P +QC C LH A Y PG +
Sbjct: 326 --CSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGA---------MYAPGEVTIA 374
Query: 1505 VCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTC 1564
C++ R W C + G C+ G TFD + F GTC
Sbjct: 375 ACQTC-RCTLGRWVCTERPCPGH--------------CSLEGGSFVTTFDARPYRFHGTC 419
Query: 1565 TYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGH 1624
TY+L + + + +++ +++ E S + V+++ D I + + V NG
Sbjct: 420 TYILLQS--PQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQD-KIVISQDEVVTNNGE 476
Query: 1625 RVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVE--VTVPSSYGGQLCGLCGN 1682
LP + + R +S + + T+FGL++ + + VTV + GQ GLCGN
Sbjct: 477 AKWLP-YKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGN 535
Query: 1683 YNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNC 1742
+N ++ DD G + +W+ P P S + + A +C
Sbjct: 536 FNGDTTDDFTTSMGIAEGTASLFVDSWRAGNC--PAALERETDPCSMSQLNKVCA-ETHC 592
Query: 1743 AILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP-A 1801
++L+ F +CH V P + CV+ C + +C +L Y C+ G
Sbjct: 593 SMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWG 652
Query: 1802 WRNRT-FCPMRCPPGSSYSPCSSPCPDTCSSINN-PRDCPKALPCAESCECQKGHILSGT 1859
WR+ C + C +++S S C TC S+++ +C + + C C G L+
Sbjct: 653 WRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQK 712
Query: 1860 -SCVPLGQCGC 1869
CV QC C
Sbjct: 713 GECVRKAQCPC 723
Score = 206 bits (525), Expect = 2e-52
Identities = 221/948 (23%), Positives = 345/948 (36%), Gaps = 153/948 (16%)
Query: 971 IPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSV- 1029
I T+ LT+ + ++ E P + + + P P P + A L S ++ M
Sbjct: 231 ICTQLLTLVAPECSVSKE-PFVLSCQADVAAAPQPGPQNSSCATL--SEYSRQCSMVGQP 287
Query: 1030 ILGTTTTSRSSTERCPPNARYESC--ACPASCKSPRPSCGPLCREGCVCNPGFLFSD--- 1084
+ + S +CP N Y+ C AC +C +P+ SC C GC C G + +D
Sbjct: 288 VRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGTVLNDLSN 347
Query: 1085 NH-CIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNG 1143
NH C+ + C C + Y PG + + CRC G V C C H C L+ G
Sbjct: 348 NHTCVPVTQCPCVLHGAMYAPGEVTIA--ACQTCRCTLGRWV-CTERPCPGH--CSLEGG 402
Query: 1144 QYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQ 1203
+ TFD R + F G CTYIL Q D
Sbjct: 403 SF------------------VTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGV 444
Query: 1204 GQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEF 1263
S ++ VY++ + V + + G+ LP + +++ T F
Sbjct: 445 SHSETSLVAVVYLSRQDKIV-ISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSF 503
Query: 1264 GLR--VRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQ 1321
GL V+ Q YVTV + G+ GLCGN++G++ +D G G +SW+
Sbjct: 504 GLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWR 563
Query: 1322 TDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSC 1381
C + C S + + C L+ T FE C V A F+ C
Sbjct: 564 AG-----NCPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRC 618
Query: 1382 MLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREP-HFCPMACPPNSKYSLCAKPCP 1440
+ C ++ +C + C G + WR C + C N+ +S ++ C
Sbjct: 619 VYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACE 678
Query: 1441 DTCHSGFSGMFCSDRC---------VEACECNPGFVLSGL-ECIPRSQCGCLHPAGSYFK 1490
TC S SDR V+ C C G L+ EC+ ++QC C+ +
Sbjct: 679 RTCLS------LSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFIL 732
Query: 1491 VGERWYKPGCKELCVCESNNRIRCQPWR-------CRAQ---EFCGQ-QDGIYGCH---- 1535
+ G C+ N R+ C P R C+A + C Q + +G
Sbjct: 733 AEQSTVINGITCHCI---NGRLSC-PQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPT 788
Query: 1536 ----AQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPC------------------- 1572
A G A +P + +G + G C PC
Sbjct: 789 CQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRT 848
Query: 1573 -------WSRSQDSYFVVSATNENRGGIL-----------EVSYIKAV------------ 1602
W+ Q ++ + T G ++ YI A
Sbjct: 849 CSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTF 908
Query: 1603 -----HVTVFDLSISLLRGCKVMLNGHRVAL-----PVWLAQGRVTIRLSSNLVLLYTNF 1652
+V + ++ R K+ L G V L V + V + ++ + L +
Sbjct: 909 KILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLVVDI 968
Query: 1653 GLQVRYD-----GSHL-VEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLG 1706
+ RY+ H+ + + + + LCGLCGN+N N DD R +A ++L
Sbjct: 969 SIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELV 1028
Query: 1707 AAWKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFA 1766
+WK P C V C N+ +W + +IN Q F+ CH V +
Sbjct: 1029 NSWK----ESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQ-TFATCHSKVYHLPYYE 1083
Query: 1767 SCVHGQCG--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC 1812
+CV CG + GD LC ++ AYA C G WR FCP+ C
Sbjct: 1084 ACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYC 1131
Score = 167 bits (422), Expect = 2e-40
Identities = 180/775 (23%), Positives = 302/775 (38%), Gaps = 81/775 (10%)
Query: 1542 CTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSY--FVVSATNENRGGILEVSYI 1599
C+ G H+ TFD ++ F GTC Y+ C +D++ F V G I +
Sbjct: 45 CSTWGAGHFSTFDHHVYDFSGTCNYIFAATC----KDAFPTFSVQLRRGPDGSISRIIVE 100
Query: 1600 KAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVT-IRLSSNLVLLYTNFGLQVRY 1658
V +I ++ V ++LP ++T S LV L+V +
Sbjct: 101 LGASVVTVSEAIISVKDIGV------ISLPYTSNGLQITPFGQSVRLVAKQLELELEVVW 154
Query: 1659 DGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPG 1718
+ V V Y GQ+CGLCGN++ ++ + + K + + A KL + E
Sbjct: 155 GPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFL-EPHKFAALQKLDDPGEIC 213
Query: 1719 CFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGD 1778
F PS+ + L+ P+ S+ V+ Q+ A+ G
Sbjct: 214 TF--QDIPSTHVRQAQHARICTQLLTLVAPECSVSKEPFVLSCQADVAAAPQ-----PGP 266
Query: 1779 TTALCRSLQAYASLCAQAGQ-APAWRNRTFCPM-RCPPGSSYSPCSSPCPDTCSSINNPR 1836
+ C +L Y+ C+ GQ WR+ C + +CP Y C S C TCS N
Sbjct: 267 QNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCS--NPQH 324
Query: 1837 DCPKALPCAESCECQKGHILSGTS----CVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
C + C C C +G +L+ S CVP+ QC C Y P GE T C +
Sbjct: 325 SCSSS--CTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAP-GE--VTIAAC-QT 378
Query: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
C C++ C + C G C L G S +FD +
Sbjct: 379 CRCTL-GRWVCTERPCP-------------------GHCSLEGGSFVTTFDARPYRFHGT 418
Query: 1953 CTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINS 2012
CT +L++ P + ++ + +E + VY+ D ++ + + V N
Sbjct: 419 CTYILLQ--SPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQD-KIVISQDEVVTNNG 475
Query: 2013 KQVTLP-AISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGN 2071
+ LP I S+ + + + + V+ + + + G+ G+CGN
Sbjct: 476 EAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGN 535
Query: 2072 FNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRA 2131
FN + D+ + S FV+SW+ +C + L E++ +P C
Sbjct: 536 FNGDTTDDFTTSMGIAEGTASLFVDSWR----AGNCPAAL--------ERETDP---CSM 580
Query: 2132 ADLRR--AREKCEAALR-APVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFG 2188
+ L + A C LR V+ +C + ++ PF C C + + +C AL +
Sbjct: 581 SQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYV 640
Query: 2189 ATCQSQGLKPPLWRNS-SFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEG 2247
C +G+ WR+S C + C ++++ +C +C L R + +G
Sbjct: 641 HACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDG 700
Query: 2248 CICQPG-YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQC 2301
C C G Y+ + +CV ++QC C I +S V +G T C C G + C
Sbjct: 701 CNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGIT--CHCINGRLSC 753
Score = 146 bits (369), Expect = 2e-34
Identities = 146/665 (21%), Positives = 251/665 (37%), Gaps = 91/665 (13%)
Query: 1929 GVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRL 1988
G C G H+ +FD + C + C A P F + + + +
Sbjct: 43 GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAF--PTFSVQLRRGPDGS------I 94
Query: 1989 HEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVN-IKIGVQVKF 2047
+ +++ + VT+ + + + ++LP S ++ S+ + +++ ++V +
Sbjct: 95 SRIIVELGASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVW 154
Query: 2048 DGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSC 2107
+ L + + Y G++CG+CGNF+ + +E + + + +F+ K +
Sbjct: 155 GPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFV-------SEEGKFLEPHKFAALQK-- 205
Query: 2108 QSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCA 2167
+D+ Q+ PS + R A R C L V +C+ + PF++ C
Sbjct: 206 ----LDDPGEICTFQDIPSTHVRQAQHARI---CTQLLTL-VAPECS--VSKEPFVLSCQ 255
Query: 2168 NTLCEFG--GLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPL-ECPAYSSYTNCLPSC 2224
+ G + C L + C G WR+ C + +CPA Y C +C
Sbjct: 256 ADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSAC 315
Query: 2225 SPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSE----DKCVPRSQCGCKDAHGGSIPLG 2280
+C + C S+C GC C G VL++ CVP +QC C HG G
Sbjct: 316 VKTCSNPQHSCS-----SSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCV-LHGAMYAPG 369
Query: 2281 KSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYL 2340
+ V+ + C CT G C + CP CS+ G
Sbjct: 370 E--VTIAACQTCRCTLGRWVCTERPCPG---------------------HCSLEGGSFVT 406
Query: 2341 TFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV 2400
TFD YR G TY+L+++ + +G L+ +K S L V+ K+
Sbjct: 407 TFDARPYRFHGTCTYILLQSPQLPEDGA---LMAVYDKSGVSHSETSLVAVVYLSRQDKI 463
Query: 2401 QLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDF--ELVVSFGGRKNAVISLPS 2458
+ + N + +PY+ L + T F ELVV A +++
Sbjct: 464 VISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGP 523
Query: 2459 MYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEG 2518
+ G GLCGN++ + +D G + F +SW P A+ E +
Sbjct: 524 QFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAG------NCPAALERETD- 576
Query: 2519 QGAELGLRTGLQVSECSPEQLASNSTQA-CRVLADPQGPFAACHQTVAPEPFQEHCVLDL 2577
CS QL + C +L F CH TV P PF + CV
Sbjct: 577 --------------PCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQA 622
Query: 2578 CSAQD 2582
C+ ++
Sbjct: 623 CNYEE 627
Score = 112 bits (281), Expect = 4e-24
Identities = 146/558 (26%), Positives = 208/558 (37%), Gaps = 68/558 (12%)
Query: 539 LPELPPVSPVSSTGPS-ETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEK 597
+P +PP +P T P TTG + +I S T P+ P PT+
Sbjct: 1194 VPCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPS-SNHTPASPTQT 1252
Query: 598 PTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTI--STEKPT 655
P + T+ S KP S +P P+ T P+ + KPT+ +T + T
Sbjct: 1253 PLLPA---TLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRAT 1309
Query: 656 VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIP----------TEKPTISMEETII 705
T P T + +T+ +PT P+ P++P T T T
Sbjct: 1310 ASTASPATTSTAQSTTRTTMTLPT--PATSGTSPTLPKSTNQELPGTTATQTTGPRPTPA 1367
Query: 706 STEKPTI-SPEKPTIPTEKPTIPTEKST--ISPEKPTTPTEKPTIPTEKPTISPEKPTT- 761
ST PT P +PT PT T T +T +P+ P T PT + P+ P T+
Sbjct: 1368 STTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSF 1427
Query: 762 --PTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIP- 818
T PT S + T+PT P T T P+ I+ T + S +IP
Sbjct: 1428 HATTTYPTPSHPETTLPTHVPPFSTSLVT-PSTHTVITPTHAQMATSASNHSAPTGTIPP 1486
Query: 819 ----------MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTI-PTEKPTIS 867
P + + TS ++ ST K + T ST P + PT TI+
Sbjct: 1487 PTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTIT 1546
Query: 868 PEKLTIPTEKLTIPTEKPTI---PIEETT----------ISTEKLTIPTEKPTISPEKPT 914
P + T T T P TT ST +T + K T + PT
Sbjct: 1547 PNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTT--YPT 1604
Query: 915 ISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKL------TIP---TEKPTIS 965
S + T+PT P T T ST + PT + + TIP T K T S
Sbjct: 1605 PSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGS 1664
Query: 966 TEKPTIPTEKLTIPTEK---PTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAP 1022
T T PT LT ++ T K + T+ H T+T + +P +
Sbjct: 1665 TH--TAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTS-STHHAEATSTSTTNITPNPTST 1721
Query: 1023 STPMTSVILGTTTTSRSS 1040
TP +V T+ SRSS
Sbjct: 1722 GTPPMTVTTSGTSQSRSS 1739
Score = 111 bits (278), Expect = 9e-24
Identities = 110/442 (24%), Positives = 173/442 (39%), Gaps = 81/442 (18%)
Query: 1805 RTFCPMR-------CPPGSSYSPCS--------SPCPDTCSSINNPRDCPKALPCAESCE 1849
R CP R C ++ CS + C TC + C C C
Sbjct: 750 RLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPT-KCEPGCV 808
Query: 1850 CQKG-HILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTC 1908
C +G + + CVP +C C SY P G +T+ R C+CS C Q T
Sbjct: 809 CAEGLYENADGQCVPPEECPCEFSGVSY-PGGAELHTD---CRTCSCS-RGRWACQQGTH 863
Query: 1909 KPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVK-VCHPAMAL 1967
P+ C L GE H ++FDG C +L VC +
Sbjct: 864 CPS------------------TCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQ 905
Query: 1968 PFFKISAKHEK-EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGV 2026
P FKI ++ G R ++++ G V++ + T+ +
Sbjct: 906 PTFKILTENVICGNSGVTCSRAIKIFLG----------GLSVVLADRNYTVTGEEPHVQL 955
Query: 2027 SVKSSSIYSIVNIKI----GVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMM 2082
V ++ +V+I I + + ++ + + I I +CG+CGNFN +D+
Sbjct: 956 GVTPGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFET 1015
Query: 2083 PSDEVANSDSEFVNSWKDKDIDPSC--QSLLVDEQQIPAEQQENPSGNCRAADLRR--AR 2138
S VA+S+ E VNSWK+ P C S + D C RR A
Sbjct: 1016 RSRYVASSELELVNSWKE---SPLCGDVSFVTDP--------------CSLNAFRRSWAE 1058
Query: 2139 EKCEAALRAPVWAQCASRIDLTPFLVDCANTL--CEFGGLYQALCQALQAFGATCQSQGL 2196
KC + + + +A C S++ P+ C C+ GG + LC A+ A+ C +G+
Sbjct: 1059 RKC-SVINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGV 1117
Query: 2197 KPPLWRNSSFCPLECPAYSSYT 2218
WR +FCP+ C Y+++T
Sbjct: 1118 CVD-WRTPAFCPIYCGFYNTHT 1138
Score = 111 bits (278), Expect = 9e-24
Identities = 153/595 (25%), Positives = 208/595 (34%), Gaps = 106/595 (17%)
Query: 533 TCPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPT 592
T P ELP + +TGP T T PT T +P +PT P T
Sbjct: 1342 TLPKSTNQELPGTTATQTTGPRPTPASTTGPT--TPQP-----------GQPTRPTATET 1388
Query: 593 IPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTE------KPTIPSEKPTIPSEK 646
T T T P P + P+ +PS P T PT + T+P+
Sbjct: 1389 TQTRTTTEYT-TPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHV 1447
Query: 647 PTISTEKPTVPTEEPTTPTE-ETTTSMEEPVIPT----------EKPSIPTEKPSIPTEK 695
P ST T T TPT + TS PT S T P PT
Sbjct: 1448 PPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTS 1507
Query: 696 PTISMEETIISTEKPTISPEKPTIPTEKPTI-PTEKSTISPEKPTTPTEKPTIPTEKPTI 754
T S + ST K S T T P + PT +TI+P +T T P T T
Sbjct: 1508 GT-SQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATS 1566
Query: 755 SPEKPTTPTEKP---------------TISPEKLTIPT---EKPTIPTEKPTIPTEKPTI 796
S P T P T T PT + T+PT P T T
Sbjct: 1567 SRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 1626
Query: 797 STEEPTTPTE-ETTISTEKPSIPM----------------EKPTLPTEETTTSVEETTIS 839
ST TPT + S S+P PT+ + TS ++++
Sbjct: 1627 STHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLN 1686
Query: 840 TEKLTIPMEKPTIST-EKPTIPTEKPTISPEKLTIPTEKLTIPT-----EKPTIPIEETT 893
T K + + T ST T I+P + T +T+ T + + +T+
Sbjct: 1687 TAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTS 1746
Query: 894 ISTEKLTIPTEKP--------TISPEKPTISTEKPTIPTEKPT---IPTEETTISTEKLT 942
S T T P +I+P + T P T T +PT TT S T
Sbjct: 1747 TSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGT 1806
Query: 943 IP---------------TEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPT 987
P T PT S T+PT P+ ST T T + IPT +
Sbjct: 1807 TPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATS 1866
Query: 988 EK-PTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
++PT + PP + ATG + P P+T TS + +T+++ST
Sbjct: 1867 ASIHSMPTGTI----PPPTTIKATG-STHTAPPMTPTTSGTSQSPSSFSTAKTST 1916
Score = 107 bits (266), Expect = 2e-22
Identities = 142/565 (25%), Positives = 195/565 (34%), Gaps = 43/565 (7%)
Query: 544 PVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTE 603
P P ++ P T+GL P +T + T + KP+VT + T ST
Sbjct: 1271 PPRPTTAVTPQATSGL---PPTATLRSTAT--KPTVTQATTRATASTASPATTSTAQSTT 1325
Query: 604 KPTIPSEKPNMPSEKPTIPS----EKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTE 659
+ T+ P PT+P E P + T P P + T +PT PT
Sbjct: 1326 RTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTA 1385
Query: 660 EPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTI 719
TT T TTT P P S PT +P+ P ++ +T PT S + T+
Sbjct: 1386 TETTQTR-TTTEYTTPQTPHTTHSPPTAGSPVPSTGP-VTATSFHATTTYPTPSHPETTL 1443
Query: 720 PTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEK 779
PT P T T S TPT + + PT PT + T
Sbjct: 1444 PTHVPPFSTSLVTPSTHTVITPTHAQMATSAS---NHSAPTGTIPPPTTLKATGSTHTAP 1500
Query: 780 PTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSI-PMEKPTLPTEETTTSVEETTI 838
P PT T + ST + T T ST P + P T+ T+T
Sbjct: 1501 PITPTTSGTSQAHS-SFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVA 1559
Query: 839 STEKLTIPMEKPTISTEKPTIPT-EKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTE 897
T T P +T P PT P S +T + K T P+ P +TT+ T
Sbjct: 1560 HTNSATSSRPPPPFTTHSP--PTGSSPFSSTGPMTATSFKTTTTYPTPSHP--QTTLPTH 1615
Query: 898 ------KLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKL-TIPTEKPTI 950
L P+ I+P ++T TIP T +T T PT T
Sbjct: 1616 VPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTT 1675
Query: 951 S----------PEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKP-TIPTEKLTA 999
S K + T ST + T T PT P T+ T +
Sbjct: 1676 SGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQ 1735
Query: 1000 LRPPHPSP-TATGLAALVMSPHAP---STPMTSVILGTTTTSRSSTERCPPNARYESCAC 1055
R + T+T L + S H P ST TS+ T+T + +A
Sbjct: 1736 SRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPT 1795
Query: 1056 PASCKSPRPSCGPLCREGCVCNPGF 1080
P + SP P+ G V F
Sbjct: 1796 PFTTHSPPTGTTPISSTGPVTATSF 1820
Score = 94.4 bits (233), Expect = 1e-18
Identities = 142/547 (25%), Positives = 187/547 (34%), Gaps = 58/547 (10%)
Query: 540 PELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPT 599
PE+ P S + T P+ T+ T P T T S P TT P P T T
Sbjct: 1535 PEVTPTSTTTIT-PNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSS-PFSSTGPMT 1592
Query: 600 ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEK-----P 654
++ K T P+ P + T+P+ P T T PS I ++T P
Sbjct: 1593 ATSFKTTTTYPTPSHP--QTTLPTHVPPFSTSLVT-PSTHTVITPTHAQMATSASIHSMP 1649
Query: 655 TVPTEEPTT----------PTEETTTSMEEPVIP---TEKPSIPTEKPSIPTEKPTISME 701
T PTT PT TTS + T K S + T +
Sbjct: 1650 TGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATST 1709
Query: 702 ETIISTEKPTISPEKPTIPTEKPT------IPTEKSTISPEKPTTPTEKPTIPTEKPT-I 754
T T PT + P T T T K++ S T+ T P + + T I
Sbjct: 1710 STTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSI 1769
Query: 755 SPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTE-ETTISTE 813
+P +T T P T T P PT IS+ P T T +TT +
Sbjct: 1770 TPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSP--PTGTTPISSTGPVTATSFQTTTTYP 1827
Query: 814 KPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEK----PTIPTEKPTISPE 869
PS P TLPT + S T ST + IP ++ PT PT
Sbjct: 1828 TPSHP--HTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKA 1885
Query: 870 KLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTI 929
+ T PT T ++ ST K + T S P ++ T T K T
Sbjct: 1886 TGSTHTAPPMTPTTSGTSQ-SPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTS 1944
Query: 930 PTEET----TISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPT----- 980
T T S +PT T SP PT S+ P T T T
Sbjct: 1945 TGTRTPVAHTTSASSSRLPTPFTTHSP-----PTGSSPFSSTGPMTATSFQTTTTYPTPS 1999
Query: 981 -EKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRS 1039
+ T+PT P T +T P + T + S STP +V TT +
Sbjct: 2000 HPQTTLPTHVPPFSTSLVT---PSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATG 2056
Query: 1040 STERCPP 1046
ST PP
Sbjct: 2057 STHTAPP 2063
Score = 93.2 bits (230), Expect = 3e-18
Identities = 165/692 (23%), Positives = 237/692 (34%), Gaps = 141/692 (20%)
Query: 535 PVKVLPELPPV--SPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPT 592
P PP +P+SSTGP T TT PT T
Sbjct: 1794 PTPFTTHSPPTGTTPISSTGPVTATSF------------------QTTTTYPTPSHPHTT 1835
Query: 593 IPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTE 652
+PT P+ ST T + +P+ S + PT PT + T
Sbjct: 1836 LPTHVPSFSTSLVTPSTHTVIIPTHTQMATSAS---IHSMPTGTIPPPTTIKATGSTHTA 1892
Query: 653 KPTVPTEEPTTP------TEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIS 706
P PT T+ T +T+TS+ T P + PT I+ + T
Sbjct: 1893 PPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT------PTSTTNITPKHTSTG 1946
Query: 707 TEKP---TISPEKPTIPTEKPTI--PTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTT 761
T P T S +PT T PT S S P T T T T PT S + T
Sbjct: 1947 TRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTY-PTPSHPQTTL 2005
Query: 762 PTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSI--PM 819
PT P S +T P+ I T + T ST T P T +T PM
Sbjct: 2006 PTHVPPFSTSLVT-PSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPM 2064
Query: 820 EKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPT---IPTEKPTIS----PEKLT 872
T T +T +S T S+ ++ P S+ +P I T+ P +S P T
Sbjct: 2065 TVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTT 2124
Query: 873 --------------------IPTEKLTIPTEKPTI---------PIEETTISTEKLTIPT 903
+P+ + T P++ P+ TT+S+ + +
Sbjct: 2125 NQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLS 2184
Query: 904 EKPTISP--EKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPE-------- 953
PT + P + T + T+P ++ T +P T+SP
Sbjct: 2185 THPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASS 2244
Query: 954 --------KLTIPTEK-PTISTEKPTIPTEKLT--IPTEKPTIPTEKPT-IPTEKLTALR 1001
+ T T P S++ T + LT +PT T T IPT +T L
Sbjct: 2245 TIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLT 2304
Query: 1002 PPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCK- 1060
HP PT +SP T+ L ++ T+ ST P +A S P
Sbjct: 2305 TRHPGPT--------LSP-------TTRFLTSSLTAHGST---PASAPVSSLGTPTPTSP 2346
Query: 1061 ---SPRPSCGPLCREGCVCNPGFLFSDNHCIQASS-----------CNCFYNNDYYEPGA 1106
S R + +GC+ N + CI A+S C+C YE
Sbjct: 2347 GVCSVREQQEEITFKGCMANVTVTRCEGACISAASFNIITQQVDARCSCCRPLHSYEQQL 2406
Query: 1107 EWFSPNCTEHCRCWPGSRVECQISQCGTHTVC 1138
E P+ + PG R+ + Q +H VC
Sbjct: 2407 ELPCPDPST-----PGRRLVLTL-QVFSHCVC 2432
Score = 84.3 bits (207), Expect = 2e-15
Identities = 89/356 (25%), Positives = 136/356 (38%), Gaps = 36/356 (10%)
Query: 701 EETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPT 760
EE + P +P+ PT P + PT + + + P T+ T T S P
Sbjct: 1189 EEGVCVPCMPPTTPQPPTTP-QLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPA 1247
Query: 761 TPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPME 820
+PT+ P + T+ + KPT + +P PT T PT + KP++
Sbjct: 1248 SPTQTPLLPA---TLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQA 1304
Query: 821 KPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIP--------------TEKPTI 866
+ + T ST + T+ + P S PT+P T P
Sbjct: 1305 TTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRP 1364
Query: 867 SPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEK 926
+P T PT T +P P T T + TE T P+ P + PT +
Sbjct: 1365 TPASTTGPT------TPQPGQPTRPTATETTQTRTTTEYTT--PQTPHTTHSPPTAGSPV 1416
Query: 927 PTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTE-KPTI 985
P+ T T ++ T T PT S + T+PT P ST T T + PT +
Sbjct: 1417 PS--TGPVTATSFHAT--TTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMAT 1472
Query: 986 PTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
+ PT + PP + ATG + P P+T TS + +T+++ T
Sbjct: 1473 SASNHSAPTGTI----PPPTTLKATG-STHTAPPITPTTSGTSQAHSSFSTNKTPT 1523
Score = 81.3 bits (199), Expect = 1e-14
Identities = 99/375 (26%), Positives = 141/375 (37%), Gaps = 53/375 (14%)
Query: 689 PSIPTEKPTISMEETIISTEKPTISPEKPT-IPTEKPTIPTEKSTISPEKPTT---PTEK 744
PS P P ++E ++ E+ +P PT P +T P+ PTT PT+
Sbjct: 1163 PSQPQSVPGSNIEGCYNCSQDEYFDHEEGVCVPCMPPTTPQPPTT--PQLPTTGSRPTQV 1220
Query: 745 PTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTP 804
+ TI T P+ +P PT+ P +P T+ + KPT S+ EP P
Sbjct: 1221 WPMTGTSTTIGLLSSTGPSPSSNHTPAS---PTQTPLLPA---TLTSSKPTASSGEPPRP 1274
Query: 805 TEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKP 864
T T P LP T S T+ T + T ST P +
Sbjct: 1275 TTAVT--------PQATSGLPPTATLRSTATKPTVTQATT----RATASTASPATTSTAQ 1322
Query: 865 TISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPT 924
+ + +T+PT + PT+P + ++L T T P ST PT P
Sbjct: 1323 STTRTTMTLPTPATS--GTSPTLPKS----TNQELPGTTATQTTGPRPTPASTTGPTTPQ 1376
Query: 925 E-KPTIPTE----ETTISTEKLTIPTEKPTISPEKL--TIPTEKPTISTE------KPTI 971
+PT PT +T +TE T T T SP +P+ P +T PT
Sbjct: 1377 PGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTP 1436
Query: 972 PTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVIL 1031
+ T+PT P T T T T + P H A + S S P ++
Sbjct: 1437 SHPETTLPTHVPPFSTSLVTPSTH--TVITPTH--------AQMATSASNHSAPTGTIPP 1486
Query: 1032 GTTTTSRSSTERCPP 1046
TT + ST PP
Sbjct: 1487 PTTLKATGSTHTAPP 1501
Score = 80.9 bits (198), Expect = 2e-14
Identities = 118/516 (22%), Positives = 197/516 (38%), Gaps = 93/516 (18%)
Query: 2097 SWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASR 2156
S+ + + +C SL ++ P C D +K E +A QC
Sbjct: 671 SYNSQACERTCLSL--SDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKA----QCPCI 724
Query: 2157 IDLTPFLVDCANTL-------CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPL 2209
++ F++ +T+ C G L + Q Q F A+CQ+ P +++ S
Sbjct: 725 LEGYKFILAEQSTVINGITCHCINGRL--SCPQRPQMFLASCQA----PKTFKSCS---- 774
Query: 2210 ECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPG-YVLSEDKCVPRSQCG 2268
SS +C+P+C L A VP+ C GC+C G Y ++ +CVP +C
Sbjct: 775 ----QSSENKFGAACAPTCQMLATGV--ACVPTKCEPGCVCAEGLYENADGQCVPPEECP 828
Query: 2269 CKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKS 2328
C+ + G S P G + + + C C C+ G + C G+HC T
Sbjct: 829 CEFS-GVSYP-GGAELHTDC-RTCSCSRGR-----WACQQGTHCPST------------- 867
Query: 2329 EQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFL 2388
C++YG+ +TFDG + G Y+L V + + + N I
Sbjct: 868 --CTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTEN-------VICG 918
Query: 2389 QEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTD------FEL 2442
+T K+ L GL +V+ ++ V H+++ + L LV D + L
Sbjct: 919 NSGVTCSRAIKIFL-GGLSVVLADRNYTVT-GEEPHVQLGVTPGALSLVVDISIPGRYNL 976
Query: 2443 VVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTE 2502
+ + +I + + + GLCGN++ N K+D S + + NSW
Sbjct: 977 TLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSW----- 1031
Query: 2503 DALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQL-ASNSTQACRVLADPQGPFAACH 2561
+E ++ T CS S + + C V+ FA CH
Sbjct: 1032 ------------KESPLCGDVSFVT----DPCSLNAFRRSWAERKCSVINSQ--TFATCH 1073
Query: 2562 QTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGH 2597
V P+ E CV D C + E L C ++ +
Sbjct: 1074 SKVYHLPYYEACVRDACGCDSGGDCECL-CDAVAAY 1108
Score = 62.8 bits (151), Expect = 5e-09
Identities = 97/418 (23%), Positives = 155/418 (37%), Gaps = 87/418 (20%)
Query: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTV-DVLPEGVEPLLVEGRNKMDPPRSSIFL 2388
QCS +G + TFD Y G Y+ T D P L + P S +
Sbjct: 44 QCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQL------RRGPDGS---I 94
Query: 2389 QEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVT---DFELVVS 2445
+I + V + + V + +++PY N L++T +GQ + LV + EL V
Sbjct: 95 SRIIVELGASVVTVSEAIISVKDIGVISLPYTSNG-LQITPFGQSVRLVAKQLELELEVV 153
Query: 2446 FGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDAL 2505
+G + ++ + Y G + GLCGN+D N+ + G + + F ++ +
Sbjct: 154 WGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEP-HKFAALQKLDDPGEI 212
Query: 2506 LRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVA 2565
F + IP+ Q + T L ++ +PE C +V+
Sbjct: 213 CTF-QDIPSTHVRQAQHARICTQL-LTLVAPE----------------------C--SVS 246
Query: 2566 PEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRPRGL 2625
EPF C D+ +A P Q C LS Y S++ QP R
Sbjct: 247 KEPFVLSCQADVAAAPQPGPQNS-SCATLSE------------YSRQCSMVGQPVR---- 289
Query: 2626 RGPLRGRLRQHPRLCLQWHPEPPLADCG-CTSNGIYYQLGSSFLTEDCSQRCTCASSRIL 2684
+W P L G C +N +Y + GS+ + + + +C+SS
Sbjct: 290 ----------------RWR-SPGLCSVGQCPANQVYQECGSACVKTCSNPQHSCSSSCTF 332
Query: 2685 LCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQCREQG-----ATFTCECEVG 2737
C C G V ++ C P + C PC G G A TC C +G
Sbjct: 333 GC---FCPEGTVLNDLSNNHTCVPVTQC---PCVLHGAMYAPGEVTIAACQTCRCTLG 384
Score = 60.5 bits (145), Expect = 2e-08
Identities = 68/272 (25%), Positives = 102/272 (37%), Gaps = 29/272 (10%)
Query: 815 PSIPMEKPTLPTEET-TTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTI 873
PS P P E S +E E + +P PT T +P + PT
Sbjct: 1163 PSQPQSVPGSNIEGCYNCSQDEYFDHEEGVCVPCMPPT--TPQPPTTPQLPTTGSR---- 1216
Query: 874 PTEKLTIPTEKPTIPIEETT----ISTEKLTIPTEKP----TISPEKPTISTEKPTIPTE 925
PT+ + TI + +T S PT+ P T++ KPT S+ +P PT
Sbjct: 1217 PTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTT 1276
Query: 926 KPTIPTEETTISTEKLTIPTEKPTISPE--KLTIPTEKPTISTEKPTIPTEKLTIPTE-- 981
T T L KPT++ + T T P ++ + +T+PT
Sbjct: 1277 AVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPAT 1336
Query: 982 ---KPTIP-TEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTS 1037
PT+P + +P T P P+P +T P P+ P + T TT+
Sbjct: 1337 SGTSPTLPKSTNQELPGTTATQTTGPRPTPAST-TGPTTPQPGQPTRPTATETTQTRTTT 1395
Query: 1038 RSSTERCPPNARYESCACPASCKSPRPSCGPL 1069
+T + P P + SP PS GP+
Sbjct: 1396 EYTTPQTPHTTH-----SPPTAGSPVPSTGPV 1422
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 197 bits (502), Expect = 9e-50
Identities = 163/515 (31%), Positives = 211/515 (40%), Gaps = 39/515 (7%)
Query: 450 VEFAYHMYGLGEGTMLELLLGS---PAG--SPPIPLWKRVGSQRPYWQNTSVTVPSGHQQ 504
+E ++ GLG + GS P G SP + W + + P + S +V SG
Sbjct: 1484 MEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGAT--PAYGAWSPSVGSG--- 1538
Query: 505 PMQLIFKGIQG-SNTASVVAMGFILINPGTCPVKVLPELPPVSPVSSTGPSETTGLTENP 563
+ G G S +A+ A GF +PG P P SP S+ + G +P
Sbjct: 1539 ----MTPGAAGFSPSAASDASGF---SPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSP 1591
Query: 564 TISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPS 623
+ S P P T P P+ PT + PT PS P P+ PT PS
Sbjct: 1592 SYSPTSPAYEPRSPGGYT---------PQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPS 1642
Query: 624 EKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPS 683
PT + PT PS PT PS PT + PT P+ PT+P+ T+ P P+ P+
Sbjct: 1643 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1702
Query: 684 IPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTE 743
P+ P+ P+ PT + PT PT P+ PT P+ T PT+P
Sbjct: 1703 SPSYSPTSPSYSPT-------SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNY 1755
Query: 744 KPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTT 803
PT P+ PT PT+P PT T P+ PT P+ PT P+ P+ P +
Sbjct: 1756 TPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQS 1815
Query: 804 PTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKL-TIPMEKPTISTEKPTIPTE 862
PT + + PS P PT P + T TS + S E T P PT PT P
Sbjct: 1816 PTYTPSSPSYSPSSPSYSPTSP-KYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKY 1874
Query: 863 KPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPT---ISPEKPTISTEK 919
PT T P T PT PT P+ T T PT PT SP PT S
Sbjct: 1875 SPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTS 1934
Query: 920 PTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEK 954
P T PT P T T LT P P S E+
Sbjct: 1935 PKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEE 1969
Score = 184 bits (468), Expect = 8e-46
Identities = 135/428 (31%), Positives = 173/428 (40%), Gaps = 41/428 (9%)
Query: 578 SVTTEKPTVP-KEKPTIPTEKPTISTE-KPTIPSEKPNMPSE-KPTIPSEKPTILTEKPT 634
S T P P P IP+ +S PT P+ +P P P PS PT + PT
Sbjct: 1566 SPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPT 1625
Query: 635 IPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTE 694
PS PT P+ PT + PT P+ PT+P+ T+ P P+ P+ P+ P+ P+
Sbjct: 1626 SPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1685
Query: 695 KPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTI 754
PT P+ SP T P+ PT P+ T PT+P+ PT P+ PT
Sbjct: 1686 SPT-----------SPSYSP---TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS 1731
Query: 755 SPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEK 814
PT+P+ PT T P PT P+ PT P+ PT PT+P T +
Sbjct: 1732 PSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYS 1791
Query: 815 PSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIP 874
P+ P PT P+ ++ P + + PT P+ SP P
Sbjct: 1792 PTSPSYSPTSPSYSPSS------------------PRYTPQSPTYTPSSPSYSPSS---P 1830
Query: 875 TEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEET 934
+ T P PT P + T P PT PT PT PT PT P
Sbjct: 1831 SYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSP 1890
Query: 935 TISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIP---TEKPTIPTEKPT 991
T T T P PT T PT PT PT PT T P T PT P PT
Sbjct: 1891 TSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPT 1950
Query: 992 IPTEKLTA 999
PT LT+
Sbjct: 1951 SPTYSLTS 1958
Score = 172 bits (436), Expect = 4e-42
Identities = 127/408 (31%), Positives = 166/408 (40%), Gaps = 13/408 (3%)
Query: 622 PSEKPTILTEKPTIPSEKPTIPSEKPTISTE-KPTVPTEEPTTPTEETTTSMEEPVIPTE 680
P+ PT + PS P IPS +S PT P EP +P T P P+
Sbjct: 1563 PAWSPTPGSPGSPGPSS-PYIPSPGGAMSPSYSPTSPAYEPRSPGGYT------PQSPSY 1615
Query: 681 KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTT 740
P+ P+ P+ P+ PT + PT PT P+ PT P+ T PT+
Sbjct: 1616 SPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS 1675
Query: 741 PTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEE 800
P+ PT P+ PT PT+P+ PT T P+ PT P+ PT P+ PT +
Sbjct: 1676 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1735
Query: 801 PTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIP 860
PT+P+ T P+ P PT P+ T+ T T P PT + PT P
Sbjct: 1736 PTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSP 1795
Query: 861 TEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKP 920
+ PT + P PT P+ P + + T P PT P+ P
Sbjct: 1796 SYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTP 1855
Query: 921 TIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPT 980
T P PT P T T PT PT T PT PT PT P T PT
Sbjct: 1856 TSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPT 1915
Query: 981 EKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTS 1028
PT P PT PT T+ + SPT+ G SP +P+ +TS
Sbjct: 1916 YSPTSPKYSPTSPTYSPTSPKGSTYSPTSPG-----YSPTSPTYSLTS 1958
Score = 122 bits (306), Expect = 5e-27
Identities = 109/388 (28%), Positives = 152/388 (39%), Gaps = 35/388 (9%)
Query: 713 SPEKPTIP-TEKPTIPTEKSTISPE-KPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISP 770
+P P P P IP+ +SP PT+P +P P TP + P+ SP
Sbjct: 1568 TPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGY---------TP-QSPSYSP 1617
Query: 771 EKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETT 830
T P+ PT P+ PT P PT + PT+P+ T + P+ P PT P+ T
Sbjct: 1618 ---TSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1674
Query: 831 TSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIE 890
+ T + T P PT + PT P+ PT T P+ T P+ PT P
Sbjct: 1675 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1734
Query: 891 ETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTI 950
T + T P PT PT + PT P+ PT P T T P+ PT
Sbjct: 1735 SPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTS 1794
Query: 951 SPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP--TEKLTALRPPHPSPT 1008
T P+ P+ P PT + P+ P+ P+ PT P T + P P T
Sbjct: 1795 PSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYT 1854
Query: 1009 ATGLAALVMSP-HAPSTPM---TSVILGTTTTSRSSTE---------RCPPNARYESCAC 1055
T SP ++P++P TS TT S T P + +Y +
Sbjct: 1855 PTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSP 1914
Query: 1056 PASCKSPR-----PSCGPLCREGCVCNP 1078
S SP+ P+ P +G +P
Sbjct: 1915 TYSPTSPKYSPTSPTYSPTSPKGSTYSP 1942
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 192 bits (488), Expect = 4e-48
Identities = 185/599 (30%), Positives = 249/599 (41%), Gaps = 86/599 (14%)
Query: 535 PVKVLPELPPVSPVSS----TGPSETTGLTENPTISTK-------------KPTVSIEKP 577
P+ P LPP S S T ETT T+ T + K K T SIEK
Sbjct: 123 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 182
Query: 578 SVTTEKPTV-----PKEKPTIPTEKPTISTEK---PTIPSEKPNMPSEKPTIPSEKPTIL 629
S PT P K T+ P ++T K PT P E + ++PT PT +
Sbjct: 183 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT-----PTTI 237
Query: 630 TEKPTIPSEK-PTIPSEKPTISTEKPTVPTEEP--TTPTEETTTSMEEPVIPTEKPSIPT 686
PT P E PT PT E T+EP TTP E T+ +EP T K + T
Sbjct: 238 KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT 297
Query: 687 EKPSIPTEK----PTISMEETIISTEKPTISPEKPTIPTEK---PTIPTEKSTISPEKPT 739
K PT PT E + ++PT + K PT K PT P E + +P+KP
Sbjct: 298 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 357
Query: 740 TPTEKPTIPTEKPTISPEKPT-TPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTIST 798
PT P E +P++P T T++P+ + K PT + PT T PT +
Sbjct: 358 -----PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT---TTKEPAPTTTK 409
Query: 799 EEPTTPTEETTISTEKPSIPMEK---PTLPTEETTTSVEETTISTEKLTIP--MEKPTIS 853
PTTP E + +T++P+ K PT P + T+ +E +T K P +KP +
Sbjct: 410 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 469
Query: 854 TEK---PTIPTEKPTISPEKLTIPT-EKLTIPTEKPTIPIEETTISTEKL--TIPTEKPT 907
T K PT P E +P+KLT T EKL PT P + + E+L T P E
Sbjct: 470 TPKEPAPTTPKETAPTTPKKLTPTTPEKLA-----PTTPEKPAPTTPEELAPTTPEEPTP 524
Query: 908 ISPEKPTISTEK-----------PTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLT 956
+PE+P +T K PT P E +E +T K T PT +P L
Sbjct: 525 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 584
Query: 957 IPT----EKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPT--EKLTALRPPHPSPTA- 1009
P +KP PT E + +KP T K T PT ++ P P+PT
Sbjct: 585 EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 644
Query: 1010 TGLAALVMSPHAPSTPMTSV---ILGTTTTSRSSTERCPPNARYESCACPASCKSPRPS 1065
G A + AP+TP + TTT +ST P P + K P P+
Sbjct: 645 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT 703
Score = 186 bits (471), Expect = 4e-46
Identities = 180/569 (31%), Positives = 241/569 (42%), Gaps = 73/569 (12%)
Query: 535 PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEK-PSVTTEKPTVPKEKPTI 593
P P+ P +P + P+ TT PT PT E P+ T PT PKE
Sbjct: 208 PALTTPKEP--TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT 265
Query: 594 PTEKPTISTEK-----------PTIPSEKPNMPSEKPTIPSEKPTILTEK---PTIPSEK 639
T++P +T K PT P P E +KP T K PT P E
Sbjct: 266 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 325
Query: 640 -PTIPSEK-PTISTEKPTVPTEE---------PTTPTEETTTSMEEPVIPTEK-PSIPTE 687
PT P E PT PT P E PTTP E T+ +EP T K PS T
Sbjct: 326 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 385
Query: 688 KPSIPT---EKPTISMEETIISTEKPTISPEKPTIPTEK---PTIPTEKSTISPEKPTTP 741
K PT PT + E +T+ +P++P+ T K PT P E + +P+KP
Sbjct: 386 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-- 443
Query: 742 TEKPTIPTEKPTISPEKPT-TPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEE 800
PT P E +P++P T T+KP + K PT T K T PT ++
Sbjct: 444 ---PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT------TPKETAPTTPKKLT--- 491
Query: 801 PTTPTEETTISTEK--PSIPME-KPTLPTEETTTSVEETTISTEKLTIP--MEKPTISTE 855
PTTP + + EK P+ P E PT P E T T+ EE +T K P ++P +T
Sbjct: 492 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 551
Query: 856 K---PTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTE-KPTISPE 911
K PT P E +P++ T K T PT ++E +T K P E PT + E
Sbjct: 552 KEPAPTTPKEPAPTTPKETAPTTPKGTAPT-----TLKEPAPTTPKKPAPKELAPTTTKE 606
Query: 912 KPTISTEKPTIPTEKPTIPT--EETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKP 969
+ + +KP T K T PT +E +T K PT +P L ++P +T K
Sbjct: 607 PTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL----KEPAPTTPKK 662
Query: 970 TIPTEKLTIPTEKPTIPT-EKPTIPTEKLTA-LRPPHPSPTATGLAALVMSPHAPSTPMT 1027
P E T+ PT T +KP T K TA P P+PT T +P P +
Sbjct: 663 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT-TPKKPAPTTPETPPPTTS 721
Query: 1028 SVILGTTTTSRSSTERCPPNARYESCACP 1056
V TTT ++ + P + E A P
Sbjct: 722 EVSTPTTTKEPTTIHKSPDESTPELSAEP 750
Score = 166 bits (420), Expect = 3e-40
Identities = 185/604 (30%), Positives = 251/604 (41%), Gaps = 101/604 (16%)
Query: 535 PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEK-PSVTTEKPTVPKEKPTI 593
P P+ P +P ++ PS TT PT + PT + E P+ T PT PKE
Sbjct: 364 PAPTTPKEP--APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 421
Query: 594 PTEKPTISTEK---PTIPSEK-PNMPSEK-PTIPSEKPTILTEKPTIPSEKPTIPSEKPT 648
T++P +T K PT P + P P E PT P E T+KP PT P E P
Sbjct: 422 TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA-----PTTPKE-PA 475
Query: 649 ISTEKPTVPTEE----PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
+T K T PT PTTP + T+ E+P P+ P E E+PT + E
Sbjct: 476 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA-----PTTPEELAPTTPEEPTPTTPEEP 530
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPE--KPTTPTE-KPTIP--TEKPTISPEKP 759
T +P P P PT P E + +P+ PTTP E PT P T T+ P
Sbjct: 531 APTTPKAAAPNTPKEPA--PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 588
Query: 760 TTPTE------KPTISPEKLTIPTEKPTIPTEKPTIPT--EKPTISTEE---PTTP--TE 806
TTP + PT + E + +KP T K T PT ++P +T + PTTP T
Sbjct: 589 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 648
Query: 807 ETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPT--EKP 864
TT+ P+ P K P E T+ + T +T +KP +T K T PT ++P
Sbjct: 649 PTTLKEPAPTTP--KKPAPKELAPTTTKGPTSTTS------DKPAPTTPKETAPTTPKEP 700
Query: 865 TISPEKLTIPTEKLTIP-----TEKPTIPIEETTI------STEKLT------------- 900
+ K PT T P PT E TTI ST +L+
Sbjct: 701 APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 760
Query: 901 ---IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLT----IPTEKPTISPE 953
+PT K T + KP ++T TE+ T ETT + K+T TEK T S
Sbjct: 761 EPGVPTTK-TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES-- 817
Query: 954 KLTIPTEKPTISTEKPTIPTEKLTIPTE--KPTIPTEKPTIPTEKLTALRPPH----PSP 1007
K+T T + T +T + T P + T+ T P + T K TI T ++ + P P
Sbjct: 818 KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI--MNKPEETAKPKD 875
Query: 1008 TATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCG 1067
AT A P P T T+T + T P + ++ P S P
Sbjct: 876 RATNSKATTPKPQKP----TKAPKKPTSTKKPKT--MPRVRKPKTTPTPRKMTSTMPELN 929
Query: 1068 PLCR 1071
P R
Sbjct: 930 PTSR 933
Score = 147 bits (372), Expect = 1e-34
Identities = 171/579 (29%), Positives = 227/579 (39%), Gaps = 95/579 (16%)
Query: 572 VSIEKPSVTTEKPTVPKEKPTIPTEKPT------ISTEKPTIPSEKPNMPSEKPTIPSEK 625
V K + T +KPT KP + E + P + + N S P I + K
Sbjct: 66 VKDNKKNRTKKKPT---PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAK 122
Query: 626 PTILTEKPTIPSEKPTIPSEKPTISTE-----KPTVPTEEPT-TPTEETTTSMEEP---- 675
P + +P++P T T++ E K T T + T T +E TTS +E
Sbjct: 123 P--INPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIE 180
Query: 676 --------------VIPTEKPSIPTEKPSIPTEK---PTISMEETIISTEKPTISPEK-- 716
PT K T+ P++ T K PT E + ++PT + K
Sbjct: 181 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 240
Query: 717 PTIPTEKPTIPTEKSTISPEKPTTPTEK---PTIPTE---------KPTISPEKPTTPTE 764
PT P E T+ + +P++P T K PT P E PT + PTTP E
Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 300
Query: 765 KPTISPEKLTIPTEK---PTIPTE-KPTIPTE-KPTISTEEPTTPTEETTISTEKPSIPM 819
+P+K T K PT P E PT P E PT PTTP E + +KP+
Sbjct: 301 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA--- 357
Query: 820 EKPTLPTEETTTSVEE---TTISTEKLTIPME-KPTISTEKPTIPTE-KPTISPEKLTIP 874
PT P E T+ +E TT T P E PT + PT E PT + T P
Sbjct: 358 --PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 415
Query: 875 TEKLTIPTEK--PTIPIE--ETTISTEKLTIPTEKPTISPEKPTISTEK---PTIPTE-K 926
E T++ PT P E TT T P E +P++P +T K PT P E
Sbjct: 416 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 475
Query: 927 PTIPTEETTISTEKLTIPT---------EKPT-ISPEKL--TIPTEKPTISTEKPTIPTE 974
PT P E + +KLT T EKP +PE+L T P E + E+P T
Sbjct: 476 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 535
Query: 975 KLTIPT----EKPTIPTE-KPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSV 1029
K P PT P E PT P E T G A + AP+TP
Sbjct: 536 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 595
Query: 1030 ---ILGTTTTSRSSTERCPPNARYESCACPASCKSPRPS 1065
+ TTT +ST P P + K P P+
Sbjct: 596 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 634
Score = 32.7 bits (73), Expect = 5.2
Identities = 42/219 (19%), Positives = 76/219 (34%), Gaps = 7/219 (3%)
Query: 492 QNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLPELPPVSPVSST 551
+ T+ T + + + + T + T KV ++
Sbjct: 805 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 864
Query: 552 GPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEK 611
E T ++ ++K T +KP+ +KPT K+ T+P + +T PT
Sbjct: 865 NKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT--PTPRKMT 922
Query: 612 PNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTS 671
MP PT S + + T P++ P S+ ++ + E TP
Sbjct: 923 STMPELNPT--SRIAEAMLQTTTRPNQTPN--SKLVEVNPKSEDAGGAEGETPHMLLRPH 978
Query: 672 MEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKP 710
+ P + + +P P +S +ET I KP
Sbjct: 979 VFMPEVTPDMDYLPRVPNQGIIINPMLS-DETNICNGKP 1016
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 192 bits (488), Expect = 4e-48
Identities = 185/599 (30%), Positives = 249/599 (41%), Gaps = 86/599 (14%)
Query: 535 PVKVLPELPPVSPVSS----TGPSETTGLTENPTISTK-------------KPTVSIEKP 577
P+ P LPP S S T ETT T+ T + K K T SIEK
Sbjct: 164 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 223
Query: 578 SVTTEKPTV-----PKEKPTIPTEKPTISTEK---PTIPSEKPNMPSEKPTIPSEKPTIL 629
S PT P K T+ P ++T K PT P E + ++PT PT +
Sbjct: 224 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT-----PTTI 278
Query: 630 TEKPTIPSEK-PTIPSEKPTISTEKPTVPTEEP--TTPTEETTTSMEEPVIPTEKPSIPT 686
PT P E PT PT E T+EP TTP E T+ +EP T K + T
Sbjct: 279 KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT 338
Query: 687 EKPSIPTEK----PTISMEETIISTEKPTISPEKPTIPTEK---PTIPTEKSTISPEKPT 739
K PT PT E + ++PT + K PT K PT P E + +P+KP
Sbjct: 339 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 398
Query: 740 TPTEKPTIPTEKPTISPEKPT-TPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTIST 798
PT P E +P++P T T++P+ + K PT + PT T PT +
Sbjct: 399 -----PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT---TTKEPAPTTTK 450
Query: 799 EEPTTPTEETTISTEKPSIPMEK---PTLPTEETTTSVEETTISTEKLTIP--MEKPTIS 853
PTTP E + +T++P+ K PT P + T+ +E +T K P +KP +
Sbjct: 451 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 510
Query: 854 TEK---PTIPTEKPTISPEKLTIPT-EKLTIPTEKPTIPIEETTISTEKL--TIPTEKPT 907
T K PT P E +P+KLT T EKL PT P + + E+L T P E
Sbjct: 511 TPKEPAPTTPKETAPTTPKKLTPTTPEKLA-----PTTPEKPAPTTPEELAPTTPEEPTP 565
Query: 908 ISPEKPTISTEK-----------PTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLT 956
+PE+P +T K PT P E +E +T K T PT +P L
Sbjct: 566 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 625
Query: 957 IPT----EKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPT--EKLTALRPPHPSPTA- 1009
P +KP PT E + +KP T K T PT ++ P P+PT
Sbjct: 626 EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 685
Query: 1010 TGLAALVMSPHAPSTPMTSV---ILGTTTTSRSSTERCPPNARYESCACPASCKSPRPS 1065
G A + AP+TP + TTT +ST P P + K P P+
Sbjct: 686 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT 744
Score = 186 bits (471), Expect = 4e-46
Identities = 180/569 (31%), Positives = 241/569 (42%), Gaps = 73/569 (12%)
Query: 535 PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEK-PSVTTEKPTVPKEKPTI 593
P P+ P +P + P+ TT PT PT E P+ T PT PKE
Sbjct: 249 PALTTPKEP--TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT 306
Query: 594 PTEKPTISTEK-----------PTIPSEKPNMPSEKPTIPSEKPTILTEK---PTIPSEK 639
T++P +T K PT P P E +KP T K PT P E
Sbjct: 307 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 366
Query: 640 -PTIPSEK-PTISTEKPTVPTEE---------PTTPTEETTTSMEEPVIPTEK-PSIPTE 687
PT P E PT PT P E PTTP E T+ +EP T K PS T
Sbjct: 367 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 426
Query: 688 KPSIPT---EKPTISMEETIISTEKPTISPEKPTIPTEK---PTIPTEKSTISPEKPTTP 741
K PT PT + E +T+ +P++P+ T K PT P E + +P+KP
Sbjct: 427 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-- 484
Query: 742 TEKPTIPTEKPTISPEKPT-TPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEE 800
PT P E +P++P T T+KP + K PT T K T PT ++
Sbjct: 485 ---PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT------TPKETAPTTPKKLT--- 532
Query: 801 PTTPTEETTISTEK--PSIPME-KPTLPTEETTTSVEETTISTEKLTIP--MEKPTISTE 855
PTTP + + EK P+ P E PT P E T T+ EE +T K P ++P +T
Sbjct: 533 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 592
Query: 856 K---PTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTE-KPTISPE 911
K PT P E +P++ T K T PT ++E +T K P E PT + E
Sbjct: 593 KEPAPTTPKEPAPTTPKETAPTTPKGTAPT-----TLKEPAPTTPKKPAPKELAPTTTKE 647
Query: 912 KPTISTEKPTIPTEKPTIPT--EETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKP 969
+ + +KP T K T PT +E +T K PT +P L ++P +T K
Sbjct: 648 PTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL----KEPAPTTPKK 703
Query: 970 TIPTEKLTIPTEKPTIPT-EKPTIPTEKLTA-LRPPHPSPTATGLAALVMSPHAPSTPMT 1027
P E T+ PT T +KP T K TA P P+PT T +P P +
Sbjct: 704 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT-TPKKPAPTTPETPPPTTS 762
Query: 1028 SVILGTTTTSRSSTERCPPNARYESCACP 1056
V TTT ++ + P + E A P
Sbjct: 763 EVSTPTTTKEPTTIHKSPDESTPELSAEP 791
Score = 166 bits (420), Expect = 3e-40
Identities = 185/604 (30%), Positives = 251/604 (41%), Gaps = 101/604 (16%)
Query: 535 PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEK-PSVTTEKPTVPKEKPTI 593
P P+ P +P ++ PS TT PT + PT + E P+ T PT PKE
Sbjct: 405 PAPTTPKEP--APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 462
Query: 594 PTEKPTISTEK---PTIPSEK-PNMPSEK-PTIPSEKPTILTEKPTIPSEKPTIPSEKPT 648
T++P +T K PT P + P P E PT P E T+KP PT P E P
Sbjct: 463 TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA-----PTTPKE-PA 516
Query: 649 ISTEKPTVPTEE----PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
+T K T PT PTTP + T+ E+P P+ P E E+PT + E
Sbjct: 517 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA-----PTTPEELAPTTPEEPTPTTPEEP 571
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPE--KPTTPTE-KPTIP--TEKPTISPEKP 759
T +P P P PT P E + +P+ PTTP E PT P T T+ P
Sbjct: 572 APTTPKAAAPNTPKEPA--PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 629
Query: 760 TTPTE------KPTISPEKLTIPTEKPTIPTEKPTIPT--EKPTISTEE---PTTP--TE 806
TTP + PT + E + +KP T K T PT ++P +T + PTTP T
Sbjct: 630 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 689
Query: 807 ETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPT--EKP 864
TT+ P+ P K P E T+ + T +T +KP +T K T PT ++P
Sbjct: 690 PTTLKEPAPTTP--KKPAPKELAPTTTKGPTSTTS------DKPAPTTPKETAPTTPKEP 741
Query: 865 TISPEKLTIPTEKLTIP-----TEKPTIPIEETTI------STEKLT------------- 900
+ K PT T P PT E TTI ST +L+
Sbjct: 742 APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 801
Query: 901 ---IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLT----IPTEKPTISPE 953
+PT K T + KP ++T TE+ T ETT + K+T TEK T S
Sbjct: 802 EPGVPTTK-TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES-- 858
Query: 954 KLTIPTEKPTISTEKPTIPTEKLTIPTE--KPTIPTEKPTIPTEKLTALRPPH----PSP 1007
K+T T + T +T + T P + T+ T P + T K TI T ++ + P P
Sbjct: 859 KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI--MNKPEETAKPKD 916
Query: 1008 TATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCG 1067
AT A P P T T+T + T P + ++ P S P
Sbjct: 917 RATNSKATTPKPQKP----TKAPKKPTSTKKPKT--MPRVRKPKTTPTPRKMTSTMPELN 970
Query: 1068 PLCR 1071
P R
Sbjct: 971 PTSR 974
Score = 147 bits (372), Expect = 1e-34
Identities = 171/579 (29%), Positives = 227/579 (39%), Gaps = 95/579 (16%)
Query: 572 VSIEKPSVTTEKPTVPKEKPTIPTEKPT------ISTEKPTIPSEKPNMPSEKPTIPSEK 625
V K + T +KPT KP + E + P + + N S P I + K
Sbjct: 107 VKDNKKNRTKKKPT---PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAK 163
Query: 626 PTILTEKPTIPSEKPTIPSEKPTISTE-----KPTVPTEEPT-TPTEETTTSMEEP---- 675
P + +P++P T T++ E K T T + T T +E TTS +E
Sbjct: 164 P--INPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIE 221
Query: 676 --------------VIPTEKPSIPTEKPSIPTEK---PTISMEETIISTEKPTISPEK-- 716
PT K T+ P++ T K PT E + ++PT + K
Sbjct: 222 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 281
Query: 717 PTIPTEKPTIPTEKSTISPEKPTTPTEK---PTIPTE---------KPTISPEKPTTPTE 764
PT P E T+ + +P++P T K PT P E PT + PTTP E
Sbjct: 282 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 341
Query: 765 KPTISPEKLTIPTEK---PTIPTE-KPTIPTE-KPTISTEEPTTPTEETTISTEKPSIPM 819
+P+K T K PT P E PT P E PT PTTP E + +KP+
Sbjct: 342 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA--- 398
Query: 820 EKPTLPTEETTTSVEE---TTISTEKLTIPME-KPTISTEKPTIPTE-KPTISPEKLTIP 874
PT P E T+ +E TT T P E PT + PT E PT + T P
Sbjct: 399 --PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 456
Query: 875 TEKLTIPTEK--PTIPIE--ETTISTEKLTIPTEKPTISPEKPTISTEK---PTIPTE-K 926
E T++ PT P E TT T P E +P++P +T K PT P E
Sbjct: 457 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 516
Query: 927 PTIPTEETTISTEKLTIPT---------EKPT-ISPEKL--TIPTEKPTISTEKPTIPTE 974
PT P E + +KLT T EKP +PE+L T P E + E+P T
Sbjct: 517 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 576
Query: 975 KLTIPT----EKPTIPTE-KPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMTSV 1029
K P PT P E PT P E T G A + AP+TP
Sbjct: 577 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 636
Query: 1030 ---ILGTTTTSRSSTERCPPNARYESCACPASCKSPRPS 1065
+ TTT +ST P P + K P P+
Sbjct: 637 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 675
Score = 32.7 bits (73), Expect = 5.2
Identities = 42/219 (19%), Positives = 76/219 (34%), Gaps = 7/219 (3%)
Query: 492 QNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLPELPPVSPVSST 551
+ T+ T + + + + T + T KV ++
Sbjct: 846 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 905
Query: 552 GPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEK 611
E T ++ ++K T +KP+ +KPT K+ T+P + +T PT
Sbjct: 906 NKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT--PTPRKMT 963
Query: 612 PNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTS 671
MP PT S + + T P++ P S+ ++ + E TP
Sbjct: 964 STMPELNPT--SRIAEAMLQTTTRPNQTPN--SKLVEVNPKSEDAGGAEGETPHMLLRPH 1019
Query: 672 MEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKP 710
+ P + + +P P +S +ET I KP
Sbjct: 1020 VFMPEVTPDMDYLPRVPNQGIIINPMLS-DETNICNGKP 1057
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 192 bits (488), Expect = 4e-48
Identities = 185/599 (30%), Positives = 249/599 (41%), Gaps = 86/599 (14%)
Query: 535 PVKVLPELPPVSPVSS----TGPSETTGLTENPTISTK-------------KPTVSIEKP 577
P+ P LPP S S T ETT T+ T + K K T SIEK
Sbjct: 216 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 275
Query: 578 SVTTEKPTV-----PKEKPTIPTEKPTISTEK---PTIPSEKPNMPSEKPTIPSEKPTIL 629
S PT P K T+ P ++T K PT P E + ++PT PT +
Sbjct: 276 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT-----PTTI 330
Query: 630 TEKPTIPSEK-PTIPSEKPTISTEKPTVPTEEP--TTPTEETTTSMEEPVIPTEKPSIPT 686
PT P E PT PT E T+EP TTP E T+ +EP T K + T
Sbjct: 331 KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT 390
Query: 687 EKPSIPTEK----PTISMEETIISTEKPTISPEKPTIPTEK---PTIPTEKSTISPEKPT 739
K PT PT E + ++PT + K PT K PT P E + +P+KP
Sbjct: 391 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 450
Query: 740 TPTEKPTIPTEKPTISPEKPT-TPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTIST 798
PT P E +P++P T T++P+ + K PT + PT T PT +
Sbjct: 451 -----PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT---TTKEPAPTTTK 502
Query: 799 EEPTTPTEETTISTEKPSIPMEK---PTLPTEETTTSVEETTISTEKLTIP--MEKPTIS 853
PTTP E + +T++P+ K PT P + T+ +E +T K P +KP +
Sbjct: 503 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 562
Query: 854 TEK---PTIPTEKPTISPEKLTIPT-EKLTIPTEKPTIPIEETTISTEKL--TIPTEKPT 907
T K PT P E +P+KLT T EKL PT P + + E+L T P E
Sbjct: 563 TPKEPAPTTPKETAPTTPKKLTPTTPEKLA-----PTTPEKPAPTTPEELAPTTPEEPTP 617
Query: 908 ISPEKPTISTEK-----------PTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLT 956
+PE+P +T K PT P E +E +T K T PT +P L
Sbjct: 618 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 677
Query: 957 IPT----EKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPT--EKLTALRPPHPSPTA- 1009
P +KP PT E + +KP T K T PT ++ P P+PT
Sbjct: 678 EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 737
Query: 1010 TGLAALVMSPHAPSTPMTSV---ILGTTTTSRSSTERCPPNARYESCACPASCKSPRPS 1065
G A + AP+TP + TTT +ST P P + K P P+
Sbjct: 738 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT 796
Score = 186 bits (471), Expect = 4e-46
Identities = 180/569 (31%), Positives = 241/569 (42%), Gaps = 73/569 (12%)
Query: 535 PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEK-PSVTTEKPTVPKEKPTI 593
P P+ P +P + P+ TT PT PT E P+ T PT PKE
Sbjct: 301 PALTTPKEP--TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT 358
Query: 594 PTEKPTISTEK-----------PTIPSEKPNMPSEKPTIPSEKPTILTEK---PTIPSEK 639
T++P +T K PT P P E +KP T K PT P E
Sbjct: 359 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 418
Query: 640 -PTIPSEK-PTISTEKPTVPTEE---------PTTPTEETTTSMEEPVIPTEK-PSIPTE 687
PT P E PT PT P E PTTP E T+ +EP T K PS T
Sbjct: 419 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 478
Query: 688 KPSIPT---EKPTISMEETIISTEKPTISPEKPTIPTEK---PTIPTEKSTISPEKPTTP 741
K PT PT + E +T+ +P++P+ T K PT P E + +P+KP
Sbjct: 479 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-- 536
Query: 742 TEKPTIPTEKPTISPEKPT-TPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEE 800
PT P E +P++P T T+KP + K PT T K T PT ++
Sbjct: 537 ---PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT------TPKETAPTTPKKLT--- 584
Query: 801 PTTPTEETTISTEK--PSIPME-KPTLPTEETTTSVEETTISTEKLTIP--MEKPTISTE 855
PTTP + + EK P+ P E PT P E T T+ EE +T K P ++P +T
Sbjct: 585 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 644
Query: 856 K---PTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTE-KPTISPE 911
K PT P E +P++ T K T PT ++E +T K P E PT + E
Sbjct: 645 KEPAPTTPKEPAPTTPKETAPTTPKGTAPT-----TLKEPAPTTPKKPAPKELAPTTTKE 699
Query: 912 KPTISTEKPTIPTEKPTIPT--EETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKP 969
+ + +KP T K T PT +E +T K PT +P L ++P +T K
Sbjct: 700 PTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL----KEPAPTTPKK 755
Query: 970 TIPTEKLTIPTEKPTIPT-EKPTIPTEKLTA-LRPPHPSPTATGLAALVMSPHAPSTPMT 1027
P E T+ PT T +KP T K TA P P+PT T +P P +
Sbjct: 756 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT-TPKKPAPTTPETPPPTTS 814
Query: 1028 SVILGTTTTSRSSTERCPPNARYESCACP 1056
V TTT ++ + P + E A P
Sbjct: 815 EVSTPTTTKEPTTIHKSPDESTPELSAEP 843
Score = 166 bits (420), Expect = 3e-40
Identities = 185/604 (30%), Positives = 251/604 (41%), Gaps = 101/604 (16%)
Query: 535 PVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEK-PSVTTEKPTVPKEKPTI 593
P P+ P +P ++ PS TT PT + PT + E P+ T PT PKE
Sbjct: 457 PAPTTPKEP--APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 514
Query: 594 PTEKPTISTEK---PTIPSEK-PNMPSEK-PTIPSEKPTILTEKPTIPSEKPTIPSEKPT 648
T++P +T K PT P + P P E PT P E T+KP PT P E P
Sbjct: 515 TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA-----PTTPKE-PA 568
Query: 649 ISTEKPTVPTEE----PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704
+T K T PT PTTP + T+ E+P P+ P E E+PT + E
Sbjct: 569 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA-----PTTPEELAPTTPEEPTPTTPEEP 623
Query: 705 ISTEKPTISPEKPTIPTEKPTIPTEKSTISPE--KPTTPTE-KPTIP--TEKPTISPEKP 759
T +P P P PT P E + +P+ PTTP E PT P T T+ P
Sbjct: 624 APTTPKAAAPNTPKEPA--PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 681
Query: 760 TTPTE------KPTISPEKLTIPTEKPTIPTEKPTIPT--EKPTISTEE---PTTP--TE 806
TTP + PT + E + +KP T K T PT ++P +T + PTTP T
Sbjct: 682 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 741
Query: 807 ETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPT--EKP 864
TT+ P+ P K P E T+ + T +T +KP +T K T PT ++P
Sbjct: 742 PTTLKEPAPTTP--KKPAPKELAPTTTKGPTSTTS------DKPAPTTPKETAPTTPKEP 793
Query: 865 TISPEKLTIPTEKLTIP-----TEKPTIPIEETTI------STEKLT------------- 900
+ K PT T P PT E TTI ST +L+
Sbjct: 794 APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 853
Query: 901 ---IPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLT----IPTEKPTISPE 953
+PT K T + KP ++T TE+ T ETT + K+T TEK T S
Sbjct: 854 EPGVPTTK-TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES-- 910
Query: 954 KLTIPTEKPTISTEKPTIPTEKLTIPTE--KPTIPTEKPTIPTEKLTALRPPH----PSP 1007
K+T T + T +T + T P + T+ T P + T K TI T ++ + P P
Sbjct: 911 KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI--MNKPEETAKPKD 968
Query: 1008 TATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCG 1067
AT A P P T T+T + T P + ++ P S P
Sbjct: 969 RATNSKATTPKPQKP----TKAPKKPTSTKKPKT--MPRVRKPKTTPTPRKMTSTMPELN 1022
Query: 1068 PLCR 1071
P R
Sbjct: 1023 PTSR 1026
Score = 150 bits (378), Expect = 2e-35
Identities = 173/583 (29%), Positives = 229/583 (39%), Gaps = 95/583 (16%)
Query: 568 KKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPT------ISTEKPTIPSEKPNMPSEKPTI 621
KK V K + T +KPT KP + E + P + + N S P I
Sbjct: 155 KKLKVKDNKKNRTKKKPT---PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKI 211
Query: 622 PSEKPTILTEKPTIPSEKPTIPSEKPTISTE-----KPTVPTEEPT-TPTEETTTSMEEP 675
+ KP + +P++P T T++ E K T T + T T +E TTS +E
Sbjct: 212 TTAKP--INPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKET 269
Query: 676 ------------------VIPTEKPSIPTEKPSIPTEK---PTISMEETIISTEKPTISP 714
PT K T+ P++ T K PT E + ++PT +
Sbjct: 270 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 329
Query: 715 EK--PTIPTEKPTIPTEKSTISPEKPTTPTEK---PTIPTE---------KPTISPEKPT 760
K PT P E T+ + +P++P T K PT P E PT + PT
Sbjct: 330 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT 389
Query: 761 TPTEKPTISPEKLTIPTEK---PTIPTE-KPTIPTE-KPTISTEEPTTPTEETTISTEKP 815
TP E +P+K T K PT P E PT P E PT PTTP E + +KP
Sbjct: 390 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 449
Query: 816 SIPMEKPTLPTEETTTSVEE---TTISTEKLTIPME-KPTISTEKPTIPTE-KPTISPEK 870
+ PT P E T+ +E TT T P E PT + PT E PT +
Sbjct: 450 A-----PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 504
Query: 871 LTIPTEKLTIPTEK--PTIPIE--ETTISTEKLTIPTEKPTISPEKPTISTEK---PTIP 923
T P E T++ PT P E TT T P E +P++P +T K PT P
Sbjct: 505 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP 564
Query: 924 TE-KPTIPTEETTISTEKLTIPT---------EKPT-ISPEKL--TIPTEKPTISTEKPT 970
E PT P E + +KLT T EKP +PE+L T P E + E+P
Sbjct: 565 KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 624
Query: 971 IPTEKLTIPT----EKPTIPTE-KPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTP 1025
T K P PT P E PT P E T G A + AP+TP
Sbjct: 625 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 684
Query: 1026 MTSV---ILGTTTTSRSSTERCPPNARYESCACPASCKSPRPS 1065
+ TTT +ST P P + K P P+
Sbjct: 685 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 727
Score = 105 bits (261), Expect = 8e-22
Identities = 134/477 (28%), Positives = 195/477 (40%), Gaps = 61/477 (12%)
Query: 615 PSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTIST-EKPTVPTEEPTTPTEETTTSME 673
PS K P + + T S KP P++K T E + E + +E+++S
Sbjct: 73 PSSKKAPPPSGASQTIKSTTKRSPKP--PNKKKTKKVIESEEITEEHSVSENQESSSSSS 130
Query: 674 EPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKST- 732
+ I + K S + ++ + K + +KPT KP + E +
Sbjct: 131 SSSSSSTIRKIKSSKNSAANRELQKKLK---VKDNKKNRTKKKPT---PKPPVVDEAGSG 184
Query: 733 --------ISPEKPTTPTEK----PTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKP 780
+P+ TT K P I T KP I+P +P+ P T LT+ E
Sbjct: 185 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP-INP-RPSLPPNSDTSKETSLTVNKET- 241
Query: 781 TIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST 840
T+ T++ T ++ + +E TT +ET S EK S PT T ETT
Sbjct: 242 TVETKETTTTNKQTSTDGKEKTTSAKETQ-SIEKTSAKDLAPTSKVLAKPTPKAETTTKG 300
Query: 841 EKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKL- 899
LT P E PT PT P E + +P++ T T K PT P E +T+
Sbjct: 301 PALTTPKE-PT-----PTTPKEPASTTPKEPTPTTIK-----SAPTTPKEPAPTTTKSAP 349
Query: 900 TIPTEKPTISPEKPTISTEKPTIPT--EKPTIPTEETTISTEKLTIPT--EKPTISPEKL 955
T P E + ++P +T K PT ++P T ++ +T K PT +KP + K
Sbjct: 350 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 409
Query: 956 TIPT--EKPTISTEKPTIPTEKLTIPTEK----PTIPTEK-PTIPTEKLTALRPPHPSPT 1008
PT ++PT +T K PT K PT PT P + PT P E P P+PT
Sbjct: 410 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT-PKEPAPT 468
Query: 1009 ATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPS 1065
T SP P P TTT S +T + P +S P + K P P+
Sbjct: 469 TTKEP----SPTTPKEPAP-----TTTKSAPTTTKEPAPTTTKS--APTTPKEPSPT 514
Score = 97.1 bits (240), Expect = 2e-19
Identities = 114/422 (27%), Positives = 163/422 (38%), Gaps = 55/422 (13%)
Query: 685 PTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIP----TEKSTISPEKPTT 740
PT PS P +TI ST K SP+ P K I TE+ ++S + ++
Sbjct: 69 PTSPPSSKKAPPPSGASQTIKSTTKR--SPKPPNKKKTKKVIESEEITEEHSVSENQESS 126
Query: 741 PTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTE- 799
+ + + TI K + + +KL + K +K PT KP + E
Sbjct: 127 SSSSSS--SSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKK---PTPKPPVVDEA 181
Query: 800 ---------EPTTPTEETT----------ISTEKPSIPMEKPTLPTEETTTSVEETTIST 840
+ TTP TT I+T KP P +P+LP T+ +ET+++
Sbjct: 182 GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINP--RPSLPPNSDTS--KETSLTV 237
Query: 841 EKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPT-------IPIEETT 893
K T K T +T K T K + K T EK + PT P ETT
Sbjct: 238 NKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETT 297
Query: 894 ISTEKLTIPTEKPTISPEKPTISTEKPTIPT---EKPTIPTEETTISTEKL-TIPTE-KP 948
LT P E +P++P +T K PT PT P E +T+ T P E P
Sbjct: 298 TKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP 357
Query: 949 TISPEKLTIPTEKPTISTEKPTIPTEKLTIPT----EKPTIPTE-KPTIPTEKLTALRPP 1003
T + E ++P +T K PT + PT PT P + PT P E P
Sbjct: 358 TTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEP-APTTPK 416
Query: 1004 HPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPR 1063
P+PT A AP+TP + ++ + P E P + K P
Sbjct: 417 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE--PAPTTTKEPS 474
Query: 1064 PS 1065
P+
Sbjct: 475 PT 476
Score = 32.7 bits (73), Expect = 5.2
Identities = 42/219 (19%), Positives = 76/219 (34%), Gaps = 7/219 (3%)
Query: 492 QNTSVTVPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKVLPELPPVSPVSST 551
+ T+ T + + + + T + T KV ++
Sbjct: 898 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 957
Query: 552 GPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEK 611
E T ++ ++K T +KP+ +KPT K+ T+P + +T PT
Sbjct: 958 NKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT--PTPRKMT 1015
Query: 612 PNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTS 671
MP PT S + + T P++ P S+ ++ + E TP
Sbjct: 1016 STMPELNPT--SRIAEAMLQTTTRPNQTPN--SKLVEVNPKSEDAGGAEGETPHMLLRPH 1071
Query: 672 MEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKP 710
+ P + + +P P +S +ET I KP
Sbjct: 1072 VFMPEVTPDMDYLPRVPNQGIIINPMLS-DETNICNGKP 1109
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 136,011,001
Number of Sequences: 37866
Number of extensions: 7912339
Number of successful extensions: 70844
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 287
Number of HSP's successfully gapped in prelim test: 1244
Number of HSP's that attempted gapping in prelim test: 27715
Number of HSP's gapped (non-prelim): 14698
length of query: 2812
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2692
effective length of database: 13,703,598
effective search space: 36890085816
effective search space used: 36890085816
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.