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Search of human proteins with 165377137
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|165377137 poly (ADP-ribose) polymerase family, member 15
isoform 1 [Homo sapiens]
(678 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|165377137 poly (ADP-ribose) polymerase family, member 15 isof... 1364 0.0
gi|22749259 poly (ADP-ribose) polymerase family, member 15 isofo... 860 0.0
gi|154813199 poly (ADP-ribose) polymerase family, member 14 [Hom... 390 e-108
gi|12232413 poly ADP-ribose polymerase 12 [Homo sapiens] 140 5e-33
gi|38524594 TCDD-inducible poly(ADP-ribose) polymerase [Homo sap... 140 5e-33
gi|157738665 poly (ADP-ribose) polymerase family, member 10 [Hom... 134 3e-31
gi|226371718 poly (ADP-ribose) polymerase family, member 9 isofo... 124 2e-28
gi|226371716 poly (ADP-ribose) polymerase family, member 9 isofo... 124 2e-28
gi|226371714 poly (ADP-ribose) polymerase family, member 9 isofo... 124 2e-28
gi|226371712 poly (ADP-ribose) polymerase family, member 9 isofo... 124 2e-28
gi|226371710 poly (ADP-ribose) polymerase family, member 9 isofo... 124 2e-28
gi|226371706 poly (ADP-ribose) polymerase family, member 9 isofo... 124 2e-28
gi|194328777 poly (ADP-ribose) polymerase family, member 11 [Hom... 123 5e-28
gi|27477136 zinc finger antiviral protein isoform 1 [Homo sapiens] 102 1e-21
gi|20336746 H2A histone family, member Y isoform 1 [Homo sapiens] 79 2e-14
gi|4758496 H2A histone family, member Y isoform 2 [Homo sapiens] 69 1e-11
gi|93141020 H2A histone family, member Y isoform 2 [Homo sapiens] 69 1e-11
gi|93141018 H2A histone family, member Y isoform 3 [Homo sapiens] 69 1e-11
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 67 5e-11
gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens] 60 7e-09
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 57 7e-08
gi|13569840 MACRO domain containing 1 [Homo sapiens] 54 5e-07
gi|8923920 H2A histone family, member Y2 [Homo sapiens] 52 1e-06
gi|158634482 poly (ADP-ribose) polymerase family, member 3 isofo... 41 0.004
gi|158634478 poly (ADP-ribose) polymerase family, member 3 isofo... 41 0.004
gi|207450721 ganglioside induced differentiation associated prot... 39 0.021
gi|8923143 ganglioside induced differentiation associated protei... 39 0.021
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 31 3.3
gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens] 31 4.3
gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens] 30 5.6
>gi|165377137 poly (ADP-ribose) polymerase family, member 15 isoform
1 [Homo sapiens]
Length = 678
Score = 1364 bits (3531), Expect = 0.0
Identities = 678/678 (100%), Positives = 678/678 (100%)
Query: 1 MAAPGPLPAAALSPGAPTPRELMHGVAGVTSRAGRDREAGSVLPAGNRGARKASRRSSSR 60
MAAPGPLPAAALSPGAPTPRELMHGVAGVTSRAGRDREAGSVLPAGNRGARKASRRSSSR
Sbjct: 1 MAAPGPLPAAALSPGAPTPRELMHGVAGVTSRAGRDREAGSVLPAGNRGARKASRRSSSR 60
Query: 61 SMSRDNKFSKKDCLSIRNVVASIQTKEGLNLKLISGDVLYIWADVIVNSVPMNLQLGGGP 120
SMSRDNKFSKKDCLSIRNVVASIQTKEGLNLKLISGDVLYIWADVIVNSVPMNLQLGGGP
Sbjct: 61 SMSRDNKFSKKDCLSIRNVVASIQTKEGLNLKLISGDVLYIWADVIVNSVPMNLQLGGGP 120
Query: 121 LSRAFLQKAGPMLQKELDDRRRETEEKVGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSW 180
LSRAFLQKAGPMLQKELDDRRRETEEKVGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSW
Sbjct: 121 LSRAFLQKAGPMLQKELDDRRRETEEKVGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSW 180
Query: 181 QIMANIIKKCLTTVEVLSFSSITFPMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSP 240
QIMANIIKKCLTTVEVLSFSSITFPMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSP
Sbjct: 181 QIMANIIKKCLTTVEVLSFSSITFPMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSP 240
Query: 241 LQEVHFLVYTNDDEGCQAFLDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMK 300
LQEVHFLVYTNDDEGCQAFLDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMK
Sbjct: 241 LQEVHFLVYTNDDEGCQAFLDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMK 300
Query: 301 IGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHR 360
IGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHR
Sbjct: 301 IGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHR 360
Query: 361 DFIITPGGCLKCKIIIHVPGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITV 420
DFIITPGGCLKCKIIIHVPGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITV
Sbjct: 361 DFIITPGGCLKCKIIIHVPGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITV 420
Query: 421 ADNIIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTC 480
ADNIIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTC
Sbjct: 421 ADNIIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTC 480
Query: 481 NLPEHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVK 540
NLPEHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVK
Sbjct: 481 NLPEHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVK 540
Query: 541 KRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSA 600
KRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSA
Sbjct: 541 KRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSA 600
Query: 601 KDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLF 660
KDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLF
Sbjct: 601 KDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLF 660
Query: 661 VVFFDNQAYPEYLITFTA 678
VVFFDNQAYPEYLITFTA
Sbjct: 661 VVFFDNQAYPEYLITFTA 678
>gi|22749259 poly (ADP-ribose) polymerase family, member 15 isoform
2 [Homo sapiens]
Length = 444
Score = 860 bits (2221), Expect = 0.0
Identities = 424/435 (97%), Positives = 428/435 (98%)
Query: 244 VHFLVYTNDDEGCQAFLDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGA 303
+H +V ++ QAFLDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGA
Sbjct: 10 LHNIVVVSNCFYFQAFLDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGA 69
Query: 304 ITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFI 363
ITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFI
Sbjct: 70 ITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFI 129
Query: 364 ITPGGCLKCKIIIHVPGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADN 423
ITPGGCLKCKIIIHVPGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADN
Sbjct: 130 ITPGGCLKCKIIIHVPGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADN 189
Query: 424 IIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNLP 483
IIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNLP
Sbjct: 190 IIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNLP 249
Query: 484 EHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQ 543
EHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQ
Sbjct: 250 EHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQ 309
Query: 544 MDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSAKDT 603
MDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSAKDT
Sbjct: 310 MDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSAKDT 369
Query: 604 YSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLFVVF 663
YSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLFVVF
Sbjct: 370 YSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLFVVF 429
Query: 664 FDNQAYPEYLITFTA 678
FDNQAYPEYLITFTA
Sbjct: 430 FDNQAYPEYLITFTA 444
Score = 46.2 bits (108), Expect = 1e-04
Identities = 35/144 (24%), Positives = 66/144 (45%), Gaps = 14/144 (9%)
Query: 89 LNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDRRRETEEKV 148
+ ++ +GD+ DVIVNS G +SRA L+ AG ++ E +
Sbjct: 70 ITFQVATGDIATEQVDVIVNSTARTFNRKSG-VSRAILEGAGQAVESECAVLAAQPHR-- 126
Query: 149 GNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSFSSITFPMIG 208
+ +T G L CK ++H G + + + +++++C E ++S++ P IG
Sbjct: 127 -DFIITPGGCLKCKIIIHVP------GGKDVRKTVTSVLEEC----EQRKYTSVSLPAIG 175
Query: 209 TGSLQFPKAVFAKLILSEVFEYSS 232
TG+ A I+ + ++SS
Sbjct: 176 TGNAGKNPITVADNIIDAIVDFSS 199
>gi|154813199 poly (ADP-ribose) polymerase family, member 14 [Homo
sapiens]
Length = 1801
Score = 390 bits (1002), Expect = e-108
Identities = 210/395 (53%), Positives = 275/395 (69%), Gaps = 2/395 (0%)
Query: 82 SIQTKEGLNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDRR 141
S+ + GL + L+ V DV+VNSVP++L L GPLS++ L+KAGP LQ+ELD
Sbjct: 1007 SLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVG 1066
Query: 142 RETEEKVGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSFSS 201
+ +G + TS NLDC+ VLH VAP W NG+ +S +IM +II++C+ E LS S
Sbjct: 1067 QGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITESLSLKS 1126
Query: 202 ITFPMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAFLD 261
I FP IGTG+L FPK +FA+LI+SEVF++SS + T LQEVHFL++ +D E QAF D
Sbjct: 1127 IAFPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKT--LQEVHFLLHPSDHENIQAFSD 1184
Query: 262 EFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGAITFQVATGDIATEQVDVI 321
EF + N +IP A DTQG GTVS P YEMKIG+I FQVA+GDI E+ DVI
Sbjct: 1185 EFARRANGNLVSDKIPKAKDTQGFYGTVSSPDSGVYEMKIGSIIFQVASGDITKEEADVI 1244
Query: 322 VNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFIITPGGCLKCKIIIHVPGG 381
VNST+ +FN K+GVS+AILE AGQ VE EC+ A Q D+IIT GG L+CK IIHV GG
Sbjct: 1245 VNSTSNSFNLKAGVSKAILECAGQNVERECSQQAQQRKNDYIITGGGFLRCKNIIHVIGG 1304
Query: 382 KDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQHSTPSLK 441
DV+ +V+SVL+ECE++ Y+S+ LPAIGTGNA ++P VA+ IIDAI DF + S S+K
Sbjct: 1305 NDVKSSVSSVLQECEKKNYSSICLPAIGTGNAKQHPDKVAEAIIDAIEDFVQKGSAQSVK 1364
Query: 442 TVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFS 476
VKVVIF P++L++FY +MKKR+ + + QS S
Sbjct: 1365 KVKVVIFLPQVLDVFYANMKKREGTQLSSQQSVMS 1399
Score = 283 bits (725), Expect = 3e-76
Identities = 129/196 (65%), Positives = 155/196 (79%)
Query: 481 NLPEHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVK 540
++P HW+DM Q FC+V+L P EYNT+ KF +TCS + IEKIERIQN LW SYQ K
Sbjct: 1604 DIPAHWSDMKQQNFCVVELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQAK 1663
Query: 541 KRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSA 600
K+ MD KN NE+ LFHGTDA SVP+VN++GFNRS AGKNAV+YGKGTYFAV+A+YSA
Sbjct: 1664 KKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNGFNRSYAGKNAVAYGKGTYFAVNANYSA 1723
Query: 601 KDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLF 660
DTYS+PD+NGRKH+Y VRVLTG++T G L+ PP KNP NPTDL+D+VT+N P LF
Sbjct: 1724 NDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPSLF 1783
Query: 661 VVFFDNQAYPEYLITF 676
V F+D QAYPEYLITF
Sbjct: 1784 VAFYDYQAYPEYLITF 1799
Score = 94.0 bits (232), Expect = 4e-19
Identities = 100/398 (25%), Positives = 173/398 (43%), Gaps = 31/398 (7%)
Query: 88 GLNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDR-RRETEE 146
G+ L + GD+ + DV+VN+ +L+ GG L+ A + AGP LQ + D +RE
Sbjct: 801 GVVLIVQQGDLARLPVDVVVNASNEDLKHYGG-LAAALSKAAGPELQADCDQIVKREGRL 859
Query: 147 KVGNIFMTSGCNLDCKAVLHAVAPYWNN-GAETSWQIMANIIKKCLTTVEVLSFSSITFP 205
GN ++ L V+HAV P W+ A ++ ++ L E + SI P
Sbjct: 860 LPGNATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIP 919
Query: 206 MIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAFLDEFTN 265
I +G FP + I+S + E + + L+E++ + + ++ +AF +
Sbjct: 920 AISSGVFGFPLGRCVETIVSAIKE-NFQFKKDGHCLKEIYLVDVS--EKTVEAFAEAVK- 975
Query: 266 WSRINPNKARIPMAGDTQGVVGTVSKPCFTAYE----MKIGAITFQVATGDIATEQVDVI 321
KA +P G+ + P T++E + G + + + + DV+
Sbjct: 976 ----TVFKATLPDTAAPPGLPPAAAGPGKTSWEKGSLVSPGGLQMLLVKEGVQNAKTDVV 1031
Query: 322 VNSTARTFNRKSG-VSRAILEGAGQAVESECAVL---AAQPHRDFIITPGGCLKCKIIIH 377
VNS G +S+++LE AG ++ E + A + T L C+ ++H
Sbjct: 1032 VNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMGTVLKTSSWNLDCRYVLH 1091
Query: 378 V------PGGKDVRKTVTSVLEEC----EQRKYTSVSLPAIGTGNAGKNPITVADNIIDA 427
V G K + ++ EC E S++ PAIGTGN G A+ II
Sbjct: 1092 VVAPEWRNGSTSSLKIMEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISE 1151
Query: 428 IVDFSSQHSTPSLKTVKVVIFQPELLNI--FYDSMKKR 463
+ FSS++ +L+ V ++ + NI F D +R
Sbjct: 1152 VFKFSSKNQLKTLQEVHFLLHPSDHENIQAFSDEFARR 1189
Score = 52.0 bits (123), Expect = 2e-06
Identities = 45/185 (24%), Positives = 84/185 (45%), Gaps = 17/185 (9%)
Query: 293 CFTAYEMKIGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECA 352
CF+ + G + V GD+A VDV+VN++ G++ A+ + AG ++++C
Sbjct: 792 CFSRTVLAPGVVLI-VQQGDLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCD 850
Query: 353 VLAAQPHR----DFIITPGGCLKCKIIIHVPGGK-----------DVRKTVTSVLEECEQ 397
+ + R + I+ G L +IH G + +R+ V L E+
Sbjct: 851 QIVKREGRLLPGNATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEK 910
Query: 398 RKYTSVSLPAIGTGNAGKNPITVADNIIDAIVD-FSSQHSTPSLKTVKVVIFQPELLNIF 456
KY S+++PAI +G G + I+ AI + F + LK + +V + + F
Sbjct: 911 YKYRSIAIPAISSGVFGFPLGRCVETIVSAIKENFQFKKDGHCLKEIYLVDVSEKTVEAF 970
Query: 457 YDSMK 461
+++K
Sbjct: 971 AEAVK 975
>gi|12232413 poly ADP-ribose polymerase 12 [Homo sapiens]
Length = 701
Score = 140 bits (352), Expect = 5e-33
Identities = 84/217 (38%), Positives = 116/217 (53%), Gaps = 15/217 (6%)
Query: 472 QSTFSMTTCN--------LPEHWTD--MNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYA 521
Q +M TCN +P++W + F + L EY + + F RT Y
Sbjct: 466 QDVTTMQTCNTKFPGPKSIPDYWDSSALPDPGFQKITLSSSSEEYQKVWNLFNRTLPFYF 525
Query: 522 IEKIERIQNAFLWQSYQVKKRQMDIKNDHKN-NERLLFHGTDADSVPYVNQHGFNRSCAG 580
++KIER+QN LW+ YQ +K QM +N K +ER LFHGT A V + Q F+ G
Sbjct: 526 VQKIERVQNLALWEVYQWQKGQMQKQNGGKAVDERQLFHGTSAIFVDAICQQNFDWRVCG 585
Query: 581 KNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNP 640
+ SYGKG+YFA DA+YS YSK D+ M++ RVL G F +G A V PP K
Sbjct: 586 VHGTSYGKGSYFARDAAYS--HHYSKSDTQTHT-MFLARVLVGEFVRGNASFVRPPAKEG 642
Query: 641 HNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT 677
+ +DS N+ P +FV+F +Q YPEY+I +T
Sbjct: 643 WS-NAFYDSCVNSVSDPSIFVIFEKHQVYPEYVIQYT 678
>gi|38524594 TCDD-inducible poly(ADP-ribose) polymerase [Homo
sapiens]
Length = 657
Score = 140 bits (352), Expect = 5e-33
Identities = 84/208 (40%), Positives = 119/208 (57%), Gaps = 10/208 (4%)
Query: 477 MTTCNL-PEHWTDMN-HQLFCMVQLEPGQSEYNTIKDKFTRTCSS--YAIEKIERIQNAF 532
+T+ N PE W M+ Q F V + Y I + F +T Y I +I R+QN F
Sbjct: 443 VTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQF 502
Query: 533 LWQSYQVKKRQMDIK---NDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKG 589
LW+ Y+ KK M+ K D NER LFHGT D V + +H F+ GK+A +G+G
Sbjct: 503 LWEKYKRKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQG 562
Query: 590 TYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPT-DLFD 648
+YFA ASYS +SK S G M++ +VLTG +T G G+ PPP NP + T DL+D
Sbjct: 563 SYFAKKASYS--HNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYD 620
Query: 649 SVTNNTRSPKLFVVFFDNQAYPEYLITF 676
S +N P++FV+F D+Q+YP ++I +
Sbjct: 621 SCVDNFFEPQIFVIFNDDQSYPYFVIQY 648
>gi|157738665 poly (ADP-ribose) polymerase family, member 10 [Homo
sapiens]
Length = 1025
Score = 134 bits (337), Expect = 3e-31
Identities = 66/158 (41%), Positives = 100/158 (63%)
Query: 518 SSYAIEKIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRS 577
SS + ++ER+ + L Q Y++ + ++ + + + E++L+HGT A +VP + HGFNRS
Sbjct: 846 SSIRVVRVERVSHPLLQQQYELYRERLLQRCERRPVEQVLYHGTTAPAVPDICAHGFNRS 905
Query: 578 CAGKNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPP 637
G+NA YGKG YFA AS S +D YS P+++G K ++V RVLTG + +GR GL PP
Sbjct: 906 FCGRNATVYGKGVYFARRASLSVQDRYSPPNADGHKAVFVARVLTGDYGQGRRGLRAPPL 965
Query: 638 KNPHNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLIT 675
+ P + +DS + P +FV+F D QA P +LIT
Sbjct: 966 RGPGHVLLRYDSAVDCICQPSIFVIFHDTQALPTHLIT 1003
>gi|226371718 poly (ADP-ribose) polymerase family, member 9 isoform
c [Homo sapiens]
Length = 710
Score = 124 bits (312), Expect = 2e-28
Identities = 117/402 (29%), Positives = 180/402 (44%), Gaps = 46/402 (11%)
Query: 89 LNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDR-RRETEEK 147
+ L + D+ D +VN+ +L GGG L+ A ++ G +Q+E R +
Sbjct: 83 IELSVWKDDLTTHAVDAVVNAANEDLLHGGG-LALALVKAGGFEIQEESKQFVARYGKVS 141
Query: 148 VGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSF-------- 199
G I +T L CK ++HAV P W W K V +L++
Sbjct: 142 AGEIAVTGAGRLPCKQIIHAVGPRW-----MEWDKQGCTGKLQRAIVSILNYVIYKNTHI 196
Query: 200 SSITFPMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAF 259
++ P + +G QFP + K I+ E S +P+ S L+E+H + +N+D AF
Sbjct: 197 KTVAIPALSSGIFQFPLNLCTKTIV-ETIRVSLQGKPMMSNLKEIHLV--SNEDPTVAAF 253
Query: 260 LDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGAITFQVATGDIATEQVD 319
A + G ++ +G + P F A M + +T Q+ G I + D
Sbjct: 254 ------------KAASEFILGKSE--LGQETTPSFNA--MVVNNLTLQIVQGHIEWQTAD 297
Query: 320 VIVNSTARTFNRKSGVSRAILEGAGQAVESE-CAVLAAQPHRD--FIITPGGCLKCKIII 376
VIVNS V+++IL+ AG ++SE A A Q R ++T G L CK I
Sbjct: 298 VIVNSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIY 357
Query: 377 HV------PGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVD 430
HV P + ++ + LE+C ++ TS+S PA+GTGN T A+ + D ++
Sbjct: 358 HVLWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLT 417
Query: 431 FSSQHSTPSLKTVKVVIFQP--ELLNIFYDSMKKRDLSASLN 470
F+ H L TVK VIF E+ F M KR SLN
Sbjct: 418 FAKDHVKHQL-TVKFVIFPTDLEIYKAFSSEMAKRSKMLSLN 458
>gi|226371716 poly (ADP-ribose) polymerase family, member 9 isoform
b [Homo sapiens]
Length = 819
Score = 124 bits (312), Expect = 2e-28
Identities = 117/402 (29%), Positives = 180/402 (44%), Gaps = 46/402 (11%)
Query: 89 LNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDR-RRETEEK 147
+ L + D+ D +VN+ +L GGG L+ A ++ G +Q+E R +
Sbjct: 83 IELSVWKDDLTTHAVDAVVNAANEDLLHGGG-LALALVKAGGFEIQEESKQFVARYGKVS 141
Query: 148 VGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSF-------- 199
G I +T L CK ++HAV P W W K V +L++
Sbjct: 142 AGEIAVTGAGRLPCKQIIHAVGPRW-----MEWDKQGCTGKLQRAIVSILNYVIYKNTHI 196
Query: 200 SSITFPMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAF 259
++ P + +G QFP + K I+ E S +P+ S L+E+H + +N+D AF
Sbjct: 197 KTVAIPALSSGIFQFPLNLCTKTIV-ETIRVSLQGKPMMSNLKEIHLV--SNEDPTVAAF 253
Query: 260 LDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGAITFQVATGDIATEQVD 319
A + G ++ +G + P F A M + +T Q+ G I + D
Sbjct: 254 ------------KAASEFILGKSE--LGQETTPSFNA--MVVNNLTLQIVQGHIEWQTAD 297
Query: 320 VIVNSTARTFNRKSGVSRAILEGAGQAVESE-CAVLAAQPHRD--FIITPGGCLKCKIII 376
VIVNS V+++IL+ AG ++SE A A Q R ++T G L CK I
Sbjct: 298 VIVNSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIY 357
Query: 377 HV------PGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVD 430
HV P + ++ + LE+C ++ TS+S PA+GTGN T A+ + D ++
Sbjct: 358 HVLWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLT 417
Query: 431 FSSQHSTPSLKTVKVVIFQP--ELLNIFYDSMKKRDLSASLN 470
F+ H L TVK VIF E+ F M KR SLN
Sbjct: 418 FAKDHVKHQL-TVKFVIFPTDLEIYKAFSSEMAKRSKMLSLN 458
Score = 74.3 bits (181), Expect = 3e-13
Identities = 49/154 (31%), Positives = 72/154 (46%), Gaps = 1/154 (0%)
Query: 524 KIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNA 583
K+E+I N L ++Q KK+ M+ K + LF V + GF R +
Sbjct: 635 KVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCD 694
Query: 584 VSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNP 643
YG G YF + A+ ++ +++ VLTG F +G + PPP +P
Sbjct: 695 PKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSP-GA 753
Query: 644 TDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT 677
D DSV +N SP+ FV+F QA P+YL T T
Sbjct: 754 IDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCT 787
>gi|226371714 poly (ADP-ribose) polymerase family, member 9 isoform
b [Homo sapiens]
Length = 819
Score = 124 bits (312), Expect = 2e-28
Identities = 117/402 (29%), Positives = 180/402 (44%), Gaps = 46/402 (11%)
Query: 89 LNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDR-RRETEEK 147
+ L + D+ D +VN+ +L GGG L+ A ++ G +Q+E R +
Sbjct: 83 IELSVWKDDLTTHAVDAVVNAANEDLLHGGG-LALALVKAGGFEIQEESKQFVARYGKVS 141
Query: 148 VGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSF-------- 199
G I +T L CK ++HAV P W W K V +L++
Sbjct: 142 AGEIAVTGAGRLPCKQIIHAVGPRW-----MEWDKQGCTGKLQRAIVSILNYVIYKNTHI 196
Query: 200 SSITFPMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAF 259
++ P + +G QFP + K I+ E S +P+ S L+E+H + +N+D AF
Sbjct: 197 KTVAIPALSSGIFQFPLNLCTKTIV-ETIRVSLQGKPMMSNLKEIHLV--SNEDPTVAAF 253
Query: 260 LDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGAITFQVATGDIATEQVD 319
A + G ++ +G + P F A M + +T Q+ G I + D
Sbjct: 254 ------------KAASEFILGKSE--LGQETTPSFNA--MVVNNLTLQIVQGHIEWQTAD 297
Query: 320 VIVNSTARTFNRKSGVSRAILEGAGQAVESE-CAVLAAQPHRD--FIITPGGCLKCKIII 376
VIVNS V+++IL+ AG ++SE A A Q R ++T G L CK I
Sbjct: 298 VIVNSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIY 357
Query: 377 HV------PGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVD 430
HV P + ++ + LE+C ++ TS+S PA+GTGN T A+ + D ++
Sbjct: 358 HVLWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLT 417
Query: 431 FSSQHSTPSLKTVKVVIFQP--ELLNIFYDSMKKRDLSASLN 470
F+ H L TVK VIF E+ F M KR SLN
Sbjct: 418 FAKDHVKHQL-TVKFVIFPTDLEIYKAFSSEMAKRSKMLSLN 458
Score = 74.3 bits (181), Expect = 3e-13
Identities = 49/154 (31%), Positives = 72/154 (46%), Gaps = 1/154 (0%)
Query: 524 KIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNA 583
K+E+I N L ++Q KK+ M+ K + LF V + GF R +
Sbjct: 635 KVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCD 694
Query: 584 VSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNP 643
YG G YF + A+ ++ +++ VLTG F +G + PPP +P
Sbjct: 695 PKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSP-GA 753
Query: 644 TDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT 677
D DSV +N SP+ FV+F QA P+YL T T
Sbjct: 754 IDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCT 787
>gi|226371712 poly (ADP-ribose) polymerase family, member 9 isoform
b [Homo sapiens]
Length = 819
Score = 124 bits (312), Expect = 2e-28
Identities = 117/402 (29%), Positives = 180/402 (44%), Gaps = 46/402 (11%)
Query: 89 LNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDR-RRETEEK 147
+ L + D+ D +VN+ +L GGG L+ A ++ G +Q+E R +
Sbjct: 83 IELSVWKDDLTTHAVDAVVNAANEDLLHGGG-LALALVKAGGFEIQEESKQFVARYGKVS 141
Query: 148 VGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSF-------- 199
G I +T L CK ++HAV P W W K V +L++
Sbjct: 142 AGEIAVTGAGRLPCKQIIHAVGPRW-----MEWDKQGCTGKLQRAIVSILNYVIYKNTHI 196
Query: 200 SSITFPMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAF 259
++ P + +G QFP + K I+ E S +P+ S L+E+H + +N+D AF
Sbjct: 197 KTVAIPALSSGIFQFPLNLCTKTIV-ETIRVSLQGKPMMSNLKEIHLV--SNEDPTVAAF 253
Query: 260 LDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGAITFQVATGDIATEQVD 319
A + G ++ +G + P F A M + +T Q+ G I + D
Sbjct: 254 ------------KAASEFILGKSE--LGQETTPSFNA--MVVNNLTLQIVQGHIEWQTAD 297
Query: 320 VIVNSTARTFNRKSGVSRAILEGAGQAVESE-CAVLAAQPHRD--FIITPGGCLKCKIII 376
VIVNS V+++IL+ AG ++SE A A Q R ++T G L CK I
Sbjct: 298 VIVNSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIY 357
Query: 377 HV------PGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVD 430
HV P + ++ + LE+C ++ TS+S PA+GTGN T A+ + D ++
Sbjct: 358 HVLWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLT 417
Query: 431 FSSQHSTPSLKTVKVVIFQP--ELLNIFYDSMKKRDLSASLN 470
F+ H L TVK VIF E+ F M KR SLN
Sbjct: 418 FAKDHVKHQL-TVKFVIFPTDLEIYKAFSSEMAKRSKMLSLN 458
Score = 74.3 bits (181), Expect = 3e-13
Identities = 49/154 (31%), Positives = 72/154 (46%), Gaps = 1/154 (0%)
Query: 524 KIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNA 583
K+E+I N L ++Q KK+ M+ K + LF V + GF R +
Sbjct: 635 KVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCD 694
Query: 584 VSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNP 643
YG G YF + A+ ++ +++ VLTG F +G + PPP +P
Sbjct: 695 PKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSP-GA 753
Query: 644 TDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT 677
D DSV +N SP+ FV+F QA P+YL T T
Sbjct: 754 IDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCT 787
>gi|226371710 poly (ADP-ribose) polymerase family, member 9 isoform
a [Homo sapiens]
Length = 854
Score = 124 bits (312), Expect = 2e-28
Identities = 117/402 (29%), Positives = 180/402 (44%), Gaps = 46/402 (11%)
Query: 89 LNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDR-RRETEEK 147
+ L + D+ D +VN+ +L GGG L+ A ++ G +Q+E R +
Sbjct: 118 IELSVWKDDLTTHAVDAVVNAANEDLLHGGG-LALALVKAGGFEIQEESKQFVARYGKVS 176
Query: 148 VGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSF-------- 199
G I +T L CK ++HAV P W W K V +L++
Sbjct: 177 AGEIAVTGAGRLPCKQIIHAVGPRW-----MEWDKQGCTGKLQRAIVSILNYVIYKNTHI 231
Query: 200 SSITFPMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAF 259
++ P + +G QFP + K I+ E S +P+ S L+E+H + +N+D AF
Sbjct: 232 KTVAIPALSSGIFQFPLNLCTKTIV-ETIRVSLQGKPMMSNLKEIHLV--SNEDPTVAAF 288
Query: 260 LDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGAITFQVATGDIATEQVD 319
A + G ++ +G + P F A M + +T Q+ G I + D
Sbjct: 289 ------------KAASEFILGKSE--LGQETTPSFNA--MVVNNLTLQIVQGHIEWQTAD 332
Query: 320 VIVNSTARTFNRKSGVSRAILEGAGQAVESE-CAVLAAQPHRD--FIITPGGCLKCKIII 376
VIVNS V+++IL+ AG ++SE A A Q R ++T G L CK I
Sbjct: 333 VIVNSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIY 392
Query: 377 HV------PGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVD 430
HV P + ++ + LE+C ++ TS+S PA+GTGN T A+ + D ++
Sbjct: 393 HVLWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLT 452
Query: 431 FSSQHSTPSLKTVKVVIFQP--ELLNIFYDSMKKRDLSASLN 470
F+ H L TVK VIF E+ F M KR SLN
Sbjct: 453 FAKDHVKHQL-TVKFVIFPTDLEIYKAFSSEMAKRSKMLSLN 493
Score = 74.3 bits (181), Expect = 3e-13
Identities = 49/154 (31%), Positives = 72/154 (46%), Gaps = 1/154 (0%)
Query: 524 KIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNA 583
K+E+I N L ++Q KK+ M+ K + LF V + GF R +
Sbjct: 670 KVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCD 729
Query: 584 VSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNP 643
YG G YF + A+ ++ +++ VLTG F +G + PPP +P
Sbjct: 730 PKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSP-GA 788
Query: 644 TDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT 677
D DSV +N SP+ FV+F QA P+YL T T
Sbjct: 789 IDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCT 822
>gi|226371706 poly (ADP-ribose) polymerase family, member 9 isoform
a [Homo sapiens]
Length = 854
Score = 124 bits (312), Expect = 2e-28
Identities = 117/402 (29%), Positives = 180/402 (44%), Gaps = 46/402 (11%)
Query: 89 LNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDR-RRETEEK 147
+ L + D+ D +VN+ +L GGG L+ A ++ G +Q+E R +
Sbjct: 118 IELSVWKDDLTTHAVDAVVNAANEDLLHGGG-LALALVKAGGFEIQEESKQFVARYGKVS 176
Query: 148 VGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSF-------- 199
G I +T L CK ++HAV P W W K V +L++
Sbjct: 177 AGEIAVTGAGRLPCKQIIHAVGPRW-----MEWDKQGCTGKLQRAIVSILNYVIYKNTHI 231
Query: 200 SSITFPMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAF 259
++ P + +G QFP + K I+ E S +P+ S L+E+H + +N+D AF
Sbjct: 232 KTVAIPALSSGIFQFPLNLCTKTIV-ETIRVSLQGKPMMSNLKEIHLV--SNEDPTVAAF 288
Query: 260 LDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGAITFQVATGDIATEQVD 319
A + G ++ +G + P F A M + +T Q+ G I + D
Sbjct: 289 ------------KAASEFILGKSE--LGQETTPSFNA--MVVNNLTLQIVQGHIEWQTAD 332
Query: 320 VIVNSTARTFNRKSGVSRAILEGAGQAVESE-CAVLAAQPHRD--FIITPGGCLKCKIII 376
VIVNS V+++IL+ AG ++SE A A Q R ++T G L CK I
Sbjct: 333 VIVNSVNPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRSQLVLVTKGFNLFCKYIY 392
Query: 377 HV------PGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVD 430
HV P + ++ + LE+C ++ TS+S PA+GTGN T A+ + D ++
Sbjct: 393 HVLWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNMEIKKETAAEILFDEVLT 452
Query: 431 FSSQHSTPSLKTVKVVIFQP--ELLNIFYDSMKKRDLSASLN 470
F+ H L TVK VIF E+ F M KR SLN
Sbjct: 453 FAKDHVKHQL-TVKFVIFPTDLEIYKAFSSEMAKRSKMLSLN 493
Score = 74.3 bits (181), Expect = 3e-13
Identities = 49/154 (31%), Positives = 72/154 (46%), Gaps = 1/154 (0%)
Query: 524 KIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNA 583
K+E+I N L ++Q KK+ M+ K + LF V + GF R +
Sbjct: 670 KVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGFQRMYSTPCD 729
Query: 584 VSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNP 643
YG G YF + A+ ++ +++ VLTG F +G + PPP +P
Sbjct: 730 PKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIVPPPLSP-GA 788
Query: 644 TDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT 677
D DSV +N SP+ FV+F QA P+YL T T
Sbjct: 789 IDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCT 822
>gi|194328777 poly (ADP-ribose) polymerase family, member 11 [Homo
sapiens]
Length = 338
Score = 123 bits (309), Expect = 5e-28
Identities = 77/216 (35%), Positives = 119/216 (55%), Gaps = 24/216 (11%)
Query: 482 LPEHWTDMNHQL-FCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVK 540
+P HW ++N Q+ + ++ L EYN + + F +T I++I+RIQN LW+ + K
Sbjct: 125 MPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFCRK 184
Query: 541 KRQMDIKNDHKN-NERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYS 599
K Q+ K NE++LFHGT ++ V + H F+ G + +GKGTYFA DA+YS
Sbjct: 185 KAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARDAAYS 244
Query: 600 AKDTYSKPD-SNGR------------------KHMYVVRVLTGVFTKGRAGLVTPPPKNP 640
++ + K D +G K M++ RVL G + G + + PP K+
Sbjct: 245 SR--FCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKD- 301
Query: 641 HNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITF 676
+ +L+DS ++T +PK+FVVF NQ YPEYLI F
Sbjct: 302 GSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDF 337
>gi|27477136 zinc finger antiviral protein isoform 1 [Homo sapiens]
Length = 902
Score = 102 bits (254), Expect = 1e-21
Identities = 72/238 (30%), Positives = 115/238 (48%), Gaps = 18/238 (7%)
Query: 441 KTVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNLP-EHWTDMNHQLFCMVQL 499
KT K VI +P + +Y KR S+ S+T P E + ++ + + + ++
Sbjct: 674 KTQKDVIRRPTFVPQWYVQQMKRGPDHQPAKTSSVSLTATFRPQEDFCFLSSKKYKLSEI 733
Query: 500 EPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFH 559
EY + + F + ++ IEKI++I+N+ L + KK QM K +LLF+
Sbjct: 734 HHLHPEYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQM------KEEGKLLFY 787
Query: 560 GTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVR 619
T V + + F+ + YGKG YFA DA YS K+ P M+V +
Sbjct: 788 ATSRAYVESICSNNFDSFLHETHENKYGKGIYFAKDAIYSHKNC---PYDAKNVVMFVAQ 844
Query: 620 VLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFT 677
VL G FT+G +PPP+ FDS + +P +FV+F +Q YP+Y+I +T
Sbjct: 845 VLVGKFTEGNITYTSPPPQ--------FDSCVDTRSNPSVFVIFQKDQVYPQYVIEYT 894
>gi|20336746 H2A histone family, member Y isoform 1 [Homo sapiens]
Length = 369
Score = 78.6 bits (192), Expect = 2e-14
Identities = 55/213 (25%), Positives = 106/213 (49%), Gaps = 9/213 (4%)
Query: 46 GNRGARKASRRSS--SRSMSRDNKFSKKDCLSIRNVVASIQTKEGLNLKLISGDVLYIWA 103
G +GARK+ ++ S++ S D+ V+++ G L+++ D+ I +
Sbjct: 151 GKKGARKSKKKQGEVSKAASADSTTEGTPADGF-TVLSTKSLFLGQKLQVVQADIASIDS 209
Query: 104 DVIVNSVPMNLQLGGGPLSRAFLQKAGP-MLQKELDDRRRETEEKVGNIFMTSGCNLDCK 162
D +V+ + +GG + +K G ++ L+ R++ +V +++G L K
Sbjct: 210 DAVVHPTNTDFYIGG-EVGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAK 268
Query: 163 AVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSFSSITFPMIGTGSLQFPKAVFAKL 222
V+H +P W GA+ +++ +K CL + SI FP IG+G FPK A+L
Sbjct: 269 FVIHCNSPVW--GADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQL 326
Query: 223 ILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEG 255
IL + Y ST ++S ++ V+F+++ ++ G
Sbjct: 327 ILKAISSYFVST--MSSSIKTVYFVLFDSESIG 357
Score = 54.7 bits (130), Expect = 3e-07
Identities = 49/172 (28%), Positives = 75/172 (43%), Gaps = 16/172 (9%)
Query: 307 QVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFI--- 363
QV DIA+ D +V+ T F V + + G+ E AVL + +
Sbjct: 198 QVVQADIASIDSDAVVHPTNTDFYIGGEVGNTLEKKGGK--EFVEAVLELRKKNGPLEVA 255
Query: 364 ---ITPGGCLKCKIIIHVPG---GKD-----VRKTVTSVLEECEQRKYTSVSLPAIGTGN 412
++ G L K +IH G D + KTV + L + +K S++ P+IG+G
Sbjct: 256 GAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGR 315
Query: 413 AGKNPITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRD 464
G T A I+ AI + + S+KTV V+F E + I+ M K D
Sbjct: 316 NGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLD 367
>gi|4758496 H2A histone family, member Y isoform 2 [Homo sapiens]
Length = 371
Score = 68.9 bits (167), Expect = 1e-11
Identities = 52/214 (24%), Positives = 101/214 (47%), Gaps = 9/214 (4%)
Query: 46 GNRGARKASRRSSSRSMSRDNKFSKKDCLSIRNVVASIQTKEGLNLKLISGDVLYIWA-- 103
G +GARK+ ++ + + ++ V+++ G L LI ++ +
Sbjct: 151 GKKGARKSKKQGEVSKAASADSTTEGTPADGFTVLSTKSLFLGQKLNLIHSEISNLAGFE 210
Query: 104 -DVIVNSVPMNLQLGGGPLSRAFLQKAGP-MLQKELDDRRRETEEKVGNIFMTSGCNLDC 161
+ I+N ++ L L +K G ++ L+ R++ +V +++G L
Sbjct: 211 VEAIINPTNADIDLKDD-LGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPA 269
Query: 162 KAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSFSSITFPMIGTGSLQFPKAVFAK 221
K V+H +P W GA+ +++ +K CL + SI FP IG+G FPK A+
Sbjct: 270 KFVIHCNSPVW--GADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQ 327
Query: 222 LILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEG 255
LIL + Y ST ++S ++ V+F+++ ++ G
Sbjct: 328 LILKAISSYFVST--MSSSIKTVYFVLFDSESIG 359
Score = 52.4 bits (124), Expect = 1e-06
Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 16/167 (9%)
Query: 312 DIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFI------IT 365
++A +V+ I+N T + K + + + G+ E AVL + + ++
Sbjct: 205 NLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGK--EFVEAVLELRKKNGPLEVAGAAVS 262
Query: 366 PGGCLKCKIIIHVPG---GKD-----VRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNP 417
G L K +IH G D + KTV + L + +K S++ P+IG+G G
Sbjct: 263 AGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPK 322
Query: 418 ITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRD 464
T A I+ AI + + S+KTV V+F E + I+ M K D
Sbjct: 323 QTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLD 369
>gi|93141020 H2A histone family, member Y isoform 2 [Homo sapiens]
Length = 371
Score = 68.9 bits (167), Expect = 1e-11
Identities = 52/214 (24%), Positives = 101/214 (47%), Gaps = 9/214 (4%)
Query: 46 GNRGARKASRRSSSRSMSRDNKFSKKDCLSIRNVVASIQTKEGLNLKLISGDVLYIWA-- 103
G +GARK+ ++ + + ++ V+++ G L LI ++ +
Sbjct: 151 GKKGARKSKKQGEVSKAASADSTTEGTPADGFTVLSTKSLFLGQKLNLIHSEISNLAGFE 210
Query: 104 -DVIVNSVPMNLQLGGGPLSRAFLQKAGP-MLQKELDDRRRETEEKVGNIFMTSGCNLDC 161
+ I+N ++ L L +K G ++ L+ R++ +V +++G L
Sbjct: 211 VEAIINPTNADIDLKDD-LGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPA 269
Query: 162 KAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSFSSITFPMIGTGSLQFPKAVFAK 221
K V+H +P W GA+ +++ +K CL + SI FP IG+G FPK A+
Sbjct: 270 KFVIHCNSPVW--GADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQ 327
Query: 222 LILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEG 255
LIL + Y ST ++S ++ V+F+++ ++ G
Sbjct: 328 LILKAISSYFVST--MSSSIKTVYFVLFDSESIG 359
Score = 52.4 bits (124), Expect = 1e-06
Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 16/167 (9%)
Query: 312 DIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFI------IT 365
++A +V+ I+N T + K + + + G+ E AVL + + ++
Sbjct: 205 NLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGK--EFVEAVLELRKKNGPLEVAGAAVS 262
Query: 366 PGGCLKCKIIIHVPG---GKD-----VRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNP 417
G L K +IH G D + KTV + L + +K S++ P+IG+G G
Sbjct: 263 AGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPK 322
Query: 418 ITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRD 464
T A I+ AI + + S+KTV V+F E + I+ M K D
Sbjct: 323 QTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLD 369
>gi|93141018 H2A histone family, member Y isoform 3 [Homo sapiens]
Length = 372
Score = 68.9 bits (167), Expect = 1e-11
Identities = 55/216 (25%), Positives = 103/216 (47%), Gaps = 12/216 (5%)
Query: 46 GNRGARKASRRSS--SRSMSRDNKFSKKDCLSIRNVVASIQTKEGLNLKLISGDVLYIWA 103
G +GARK+ ++ S++ S D+ V+++ G L LI ++ +
Sbjct: 151 GKKGARKSKKKQGEVSKAASADSTTEGTPADGF-TVLSTKSLFLGQKLNLIHSEISNLAG 209
Query: 104 ---DVIVNSVPMNLQLGGGPLSRAFLQKAGP-MLQKELDDRRRETEEKVGNIFMTSGCNL 159
+ I+N ++ L L +K G ++ L+ R++ +V +++G L
Sbjct: 210 FEVEAIINPTNADIDLKDD-LGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGL 268
Query: 160 DCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSFSSITFPMIGTGSLQFPKAVF 219
K V+H +P W GA+ +++ +K CL + SI FP IG+G FPK
Sbjct: 269 PAKFVIHCNSPVW--GADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTA 326
Query: 220 AKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEG 255
A+LIL + Y ST ++S ++ V+F+++ ++ G
Sbjct: 327 AQLILKAISSYFVST--MSSSIKTVYFVLFDSESIG 360
Score = 52.4 bits (124), Expect = 1e-06
Identities = 45/167 (26%), Positives = 75/167 (44%), Gaps = 16/167 (9%)
Query: 312 DIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFI------IT 365
++A +V+ I+N T + K + + + G+ E AVL + + ++
Sbjct: 206 NLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGK--EFVEAVLELRKKNGPLEVAGAAVS 263
Query: 366 PGGCLKCKIIIHVPG---GKD-----VRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNP 417
G L K +IH G D + KTV + L + +K S++ P+IG+G G
Sbjct: 264 AGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPK 323
Query: 418 ITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRD 464
T A I+ AI + + S+KTV V+F E + I+ M K D
Sbjct: 324 QTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLD 370
>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase 2 [Homo sapiens]
Length = 1166
Score = 67.0 bits (162), Expect = 5e-11
Identities = 57/208 (27%), Positives = 98/208 (47%), Gaps = 34/208 (16%)
Query: 496 MVQLEPGQSEYNTIKDKFTRTC-------------SSYAIEKIERIQNAFLWQSYQVKKR 542
++ L P E+ +++++ T + Y I KI+++ N LW+ Y +++
Sbjct: 955 LIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRK 1014
Query: 543 QMDIKNDHKNNERLLFHGTDADSVPYVN---QHGFNRSCAGKNAVSYGKGTYFAVDASYS 599
++ +N + NER+LFHG+ P+VN GF+ A + +G G YFA ++S S
Sbjct: 1015 EVSEENHNHANERMLFHGS-----PFVNAIIHKGFDERHAYIGGM-FGAGIYFAENSSKS 1068
Query: 600 AKDTYSKPDSNG-----RKHMYVV--RVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTN 652
+ Y G + Y+ ++L T G++ L K H+P SVT
Sbjct: 1069 NQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPG-HHSVTG 1127
Query: 653 ----NTRSPKLFVVFFDNQAYPEYLITF 676
N + +V++ QAYPEYLIT+
Sbjct: 1128 RPSVNGLALAEYVIYRGEQAYPEYLITY 1155
>gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens]
Length = 425
Score = 60.1 bits (144), Expect = 7e-09
Identities = 55/180 (30%), Positives = 78/180 (43%), Gaps = 12/180 (6%)
Query: 78 NVVASIQTKEGLNLK--LISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQK 135
N + Q K+ L K L GD+ + D IVN+ +L LGGG + + AGP L
Sbjct: 57 NTQETSQVKKSLTEKVSLYRGDITLLEVDAIVNAANASL-LGGGGVDGCIHRAAGPCLLA 115
Query: 136 ELDDRRRETEEKVGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSW-QIMANIIKKCLTTV 194
E R G+ +T G +L K V+H V P S + +AN K L V
Sbjct: 116 EC---RNLNGCDTGHAKITCGYDLPAKYVIHTVGPIARGHINGSHKEDLANCYKSSLKLV 172
Query: 195 EVLSFSSITFPMIGTGSLQFPKAVFAKLILSEVFEYSSST-----RPITSPLQEVHFLVY 249
+ + S+ FP I TG FP A + L+ + E+ + R I EV F +Y
Sbjct: 173 KENNIRSVAFPCISTGIYGFPNEPAAVIALNTIKEWLAKNHHEVDRIIFCVFLEVDFKIY 232
Score = 40.4 bits (93), Expect = 0.005
Identities = 34/115 (29%), Positives = 46/115 (40%), Gaps = 11/115 (9%)
Query: 311 GDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFIITPGGCL 370
GDI +VD IVN+ + GV I AG + +EC L IT G L
Sbjct: 77 GDITLLEVDAIVNAANASLLGGGGVDGCIHRAAGPCLLAECRNLNGCDTGHAKITCGYDL 136
Query: 371 KCKIIIHVPG-----------GKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAG 414
K +IH G +D+ S L+ ++ SV+ P I TG G
Sbjct: 137 PAKYVIHTVGPIARGHINGSHKEDLANCYKSSLKLVKENNIRSVAFPCISTGIYG 191
>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase [Homo sapiens]
Length = 1327
Score = 56.6 bits (135), Expect = 7e-08
Identities = 50/207 (24%), Positives = 96/207 (46%), Gaps = 32/207 (15%)
Query: 496 MVQLEPGQSEYNTIKDKFTRTC-------------SSYAIEKIERIQNAFLWQSYQVKKR 542
++ L P EY +++++ T + Y + +I+++ N L + + +++
Sbjct: 1108 LLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFCHRQK 1167
Query: 543 QMDIKNDHKNNERLLFHGTDADSVPYVN---QHGFNRSCAGKNAVSYGKGTYFAVDASYS 599
++ +N + +NER+LFHG+ P++N GF+ A + +G G YFA ++S S
Sbjct: 1168 EVSEENHNHHNERMLFHGS-----PFINAIIHKGFDERHAYIGGM-FGAGIYFAENSSKS 1221
Query: 600 AKDTYSKPDSNG-----RKHMYVV--RVLTGVFTKGRAGLVTPPPKNPHNPT---DLFDS 649
+ Y G + Y+ ++L T G++ L K H P +
Sbjct: 1222 NQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHSVIGR 1281
Query: 650 VTNNTRSPKLFVVFFDNQAYPEYLITF 676
+ N + +V++ QAYPEYLIT+
Sbjct: 1282 PSVNGLAYAEYVIYRGEQAYPEYLITY 1308
>gi|13569840 MACRO domain containing 1 [Homo sapiens]
Length = 325
Score = 53.9 bits (128), Expect = 5e-07
Identities = 42/144 (29%), Positives = 69/144 (47%), Gaps = 11/144 (7%)
Query: 91 LKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDRRRETEEKVGN 150
+ L+ D+ + D IVN+ +L LGGG + + AGP+L D+ R K G
Sbjct: 154 ISLLRSDITKLEVDAIVNAANSSL-LGGGGVDGCIHRAAGPLLT---DECRTLQSCKTGK 209
Query: 151 IFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKC-LTTVEVL---SFSSITFPM 206
+T G L K V+H V P S A ++ C L+++++L S+ FP
Sbjct: 210 AKITGGYRLPAKYVIHTVGPIAYGEPSAS---QAAELRSCYLSSLDLLLEHRLRSVAFPC 266
Query: 207 IGTGSLQFPKAVFAKLILSEVFEY 230
I TG +P A+++L+ + E+
Sbjct: 267 ISTGVFGYPCEAAAEIVLATLREW 290
Score = 44.3 bits (103), Expect = 4e-04
Identities = 36/135 (26%), Positives = 54/135 (40%), Gaps = 11/135 (8%)
Query: 312 DIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFIITPGGCLK 371
DI +VD IVN+ + GV I AG + EC L + IT G L
Sbjct: 160 DITKLEVDAIVNAANSSLLGGGGVDGCIHRAAGPLLTDECRTLQSCKTGKAKITGGYRLP 219
Query: 372 CKIIIHVPG-----------GKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITV 420
K +IH G ++R S L+ + + SV+ P I TG G
Sbjct: 220 AKYVIHTVGPIAYGEPSASQAAELRSCYLSSLDLLLEHRLRSVAFPCISTGVFGYPCEAA 279
Query: 421 ADNIIDAIVDFSSQH 435
A+ ++ + ++ QH
Sbjct: 280 AEIVLATLREWLEQH 294
>gi|8923920 H2A histone family, member Y2 [Homo sapiens]
Length = 372
Score = 52.4 bits (124), Expect = 1e-06
Identities = 52/229 (22%), Positives = 98/229 (42%), Gaps = 17/229 (7%)
Query: 32 RAGRDREAGSVLPAGNRGARKASRRSSSRSMSRDNKFSKKDCLSIRNVVASIQTKEGLNL 91
+ G+ +A + + + + +S S S D LS +++V G L
Sbjct: 144 KGGKKSKAAKPRTSKKSKPKDSDKEGTSNSTSEDGPGDGFTILSSKSLVL------GQKL 197
Query: 92 KLISGDVLYIWA---DVIVNSVPMNLQLGGGPLSRAFLQKAG--PMLQKELDDRRRETEE 146
L D+ +I + + IV+ + L + +A L+KAG L+ + R+ +
Sbjct: 198 SLTQSDISHIGSMRVEGIVHPTTAEIDLKED-IGKA-LEKAGGKEFLETVKELRKSQGPL 255
Query: 147 KVGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSFSSITFPM 206
+V ++ L K V+H P W G++ + + IK CL+ E S+ FP
Sbjct: 256 EVAEAAVSQSSGLAAKFVIHCHIPQW--GSDKCEEQLEETIKNCLSAAEDKKLKSVAFPP 313
Query: 207 IGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEG 255
+G FPK A++ L + + + S L+ V+FL++ ++ G
Sbjct: 314 FPSGRNCFPKQTAAQVTLKAISAHFDDSS--ASSLKNVYFLLFDSESIG 360
>gi|158634482 poly (ADP-ribose) polymerase family, member 3 isoform
b [Homo sapiens]
Length = 533
Score = 40.8 bits (94), Expect = 0.004
Identities = 45/159 (28%), Positives = 68/159 (42%), Gaps = 13/159 (8%)
Query: 447 IFQPELLNIFYDSM---KKRDLSASLNFQSTFSMTTCNLPEHWTDMNHQLF-CMVQL-EP 501
I PELL D + +L+ +L S T +P H D ++QL C +QL +
Sbjct: 273 INSPELLQAKKDMLLVLADIELAQALQAVSEQEKTVEEVP-HPLDRDYQLLKCQLQLLDS 331
Query: 502 GQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGT 561
G EY I+ +T S++ ++ I W+ Q + + N +LL+HGT
Sbjct: 332 GAPEYKVIQTYLEQTGSNHRCPTLQHI-----WKVNQEGEEDRFQAHSKLGNRKLLWHGT 386
Query: 562 DADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSA 600
+ V + G V GKG YFA + S SA
Sbjct: 387 NMAVVAAILTSGLRIMPHSGGRV--GKGIYFASENSKSA 423
>gi|158634478 poly (ADP-ribose) polymerase family, member 3 isoform
a [Homo sapiens]
Length = 540
Score = 40.8 bits (94), Expect = 0.004
Identities = 45/159 (28%), Positives = 68/159 (42%), Gaps = 13/159 (8%)
Query: 447 IFQPELLNIFYDSM---KKRDLSASLNFQSTFSMTTCNLPEHWTDMNHQLF-CMVQL-EP 501
I PELL D + +L+ +L S T +P H D ++QL C +QL +
Sbjct: 280 INSPELLQAKKDMLLVLADIELAQALQAVSEQEKTVEEVP-HPLDRDYQLLKCQLQLLDS 338
Query: 502 GQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGT 561
G EY I+ +T S++ ++ I W+ Q + + N +LL+HGT
Sbjct: 339 GAPEYKVIQTYLEQTGSNHRCPTLQHI-----WKVNQEGEEDRFQAHSKLGNRKLLWHGT 393
Query: 562 DADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSA 600
+ V + G V GKG YFA + S SA
Sbjct: 394 NMAVVAAILTSGLRIMPHSGGRV--GKGIYFASENSKSA 430
>gi|207450721 ganglioside induced differentiation associated protein
2 isoform b [Homo sapiens]
Length = 496
Score = 38.5 bits (88), Expect = 0.021
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 5/124 (4%)
Query: 93 LISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDRRRETEEKVGNIF 152
L GDV + IVN+ +L P+S + AGP L+++L + + G
Sbjct: 58 LWKGDVALLNCTAIVNTSNESLT-DKNPVSESIFMLAGPDLKEDLQKLKGC---RTGEAK 113
Query: 153 MTSGCNLDCKAVLHAVAPYWNNGAETSWQ-IMANIIKKCLTTVEVLSFSSITFPMIGTGS 211
+T G NL + ++H V P + + T+ + + + + L + S SS+ F +I +
Sbjct: 114 LTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAK 173
Query: 212 LQFP 215
+P
Sbjct: 174 RGYP 177
Score = 31.6 bits (70), Expect = 2.5
Identities = 27/115 (23%), Positives = 47/115 (40%), Gaps = 11/115 (9%)
Query: 311 GDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFIITPGGCL 370
GD+A IVN++ + K+ VS +I AG ++ + L + +T G L
Sbjct: 61 GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL 120
Query: 371 KCKIIIHVPGGK-----------DVRKTVTSVLEECEQRKYTSVSLPAIGTGNAG 414
+ IIH G K + +VL+ +++ +SV I + G
Sbjct: 121 AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRG 175
>gi|8923143 ganglioside induced differentiation associated protein 2
isoform a [Homo sapiens]
Length = 497
Score = 38.5 bits (88), Expect = 0.021
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 5/124 (4%)
Query: 93 LISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDRRRETEEKVGNIF 152
L GDV + IVN+ +L P+S + AGP L+++L + + G
Sbjct: 58 LWKGDVALLNCTAIVNTSNESLT-DKNPVSESIFMLAGPDLKEDLQKLKGC---RTGEAK 113
Query: 153 MTSGCNLDCKAVLHAVAPYWNNGAETSWQ-IMANIIKKCLTTVEVLSFSSITFPMIGTGS 211
+T G NL + ++H V P + + T+ + + + + L + S SS+ F +I +
Sbjct: 114 LTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAK 173
Query: 212 LQFP 215
+P
Sbjct: 174 RGYP 177
Score = 31.6 bits (70), Expect = 2.5
Identities = 27/115 (23%), Positives = 47/115 (40%), Gaps = 11/115 (9%)
Query: 311 GDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFIITPGGCL 370
GD+A IVN++ + K+ VS +I AG ++ + L + +T G L
Sbjct: 61 GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL 120
Query: 371 KCKIIIHVPGGK-----------DVRKTVTSVLEECEQRKYTSVSLPAIGTGNAG 414
+ IIH G K + +VL+ +++ +SV I + G
Sbjct: 121 AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRG 175
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 31.2 bits (69), Expect = 3.3
Identities = 24/61 (39%), Positives = 27/61 (44%), Gaps = 2/61 (3%)
Query: 4 PGPLPAAALSPGAPTPRELMHGVAGVTSRAGRDREAGSVLPAGNRGARKASRRSSSRSMS 63
PG AA L P P R L G A +R R LPA AR AS S+S+S
Sbjct: 1198 PGSATAADLRPKQPPGRGLGPGRAQAGARPPAPRSPR--LPASTSAARNASASPRSQSLS 1255
Query: 64 R 64
R
Sbjct: 1256 R 1256
>gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]
Length = 1505
Score = 30.8 bits (68), Expect = 4.3
Identities = 23/94 (24%), Positives = 34/94 (36%), Gaps = 13/94 (13%)
Query: 4 PGPLPAAALSPGAPTPRELMHGVAGVTSRAGRDREA-GSVLPAGNRGARKASRRSSSRSM 62
PGPLP+ A + P + G A S P N + A RR SS
Sbjct: 1399 PGPLPSPASATATAAPAAPEDAATSAAAAPGEGPAAPSSAPPPSNSSSSSAPRRPSSLQS 1458
Query: 63 ------------SRDNKFSKKDCLSIRNVVASIQ 84
SRDN KK ++ +++ ++
Sbjct: 1459 LFGLPEAAGARDSRDNPLRKKKAANLNSIIHRLE 1492
>gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]
Length = 330
Score = 30.4 bits (67), Expect = 5.6
Identities = 36/152 (23%), Positives = 61/152 (40%), Gaps = 15/152 (9%)
Query: 1 MAAPGPLPAAALSPGAPTPRELMHGVAGVTSRAGRDREAGSVLPAGNRGARKASRRSSSR 60
+ AP P P A SPG P EL + SR S+ A + G +AS R
Sbjct: 117 LVAPSPSPEARASPGTPGTPELRPTFSPAFSRPS---AFSSLAEASDPGPPRASLR---- 169
Query: 61 SMSRDNKFSKKDCLSIRNVVASIQTKEGLN-LKLISGDVLYIWADVIVNSV-----PMNL 114
++ + +D L + + S Q ++ N + L S + L A + S+ + L
Sbjct: 170 --AKTSPEGARDLLGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGL 227
Query: 115 QLGGGPLSRAFLQKAGPMLQKELDDRRRETEE 146
G P+ + A P+ Q + + + +E
Sbjct: 228 PGGSLPIKDLAVDSASPVYQAVIKSQNKPEDE 259
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,396,384
Number of Sequences: 37866
Number of extensions: 1189070
Number of successful extensions: 3923
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 3798
Number of HSP's gapped (non-prelim): 62
length of query: 678
length of database: 18,247,518
effective HSP length: 109
effective length of query: 569
effective length of database: 14,120,124
effective search space: 8034350556
effective search space used: 8034350556
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.