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Search of human proteins with 164414431
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|164414431 netrin G1 isoform 1 [Homo sapiens]
(539 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|164414431 netrin G1 isoform 1 [Homo sapiens] 1174 0.0
gi|164414437 netrin G1 isoform 2 [Homo sapiens] 829 0.0
gi|54312078 netrin G1 isoform 3 [Homo sapiens] 779 0.0
gi|190014607 netrin G2 [Homo sapiens] 691 0.0
gi|148613884 netrin 1 [Homo sapiens] 241 9e-64
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 224 1e-58
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 212 6e-55
gi|5453810 netrin 3 [Homo sapiens] 199 7e-51
gi|93204871 netrin 4 [Homo sapiens] 187 2e-47
gi|21264602 laminin alpha 5 [Homo sapiens] 187 2e-47
gi|143770880 laminin, beta 4 [Homo sapiens] 180 3e-45
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 176 5e-44
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 176 5e-44
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 171 2e-42
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 169 5e-42
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 169 5e-42
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 162 9e-40
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 162 9e-40
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 162 9e-40
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 160 2e-39
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 159 5e-39
gi|219842266 usherin isoform B [Homo sapiens] 127 2e-29
gi|219842259 usherin isoform A [Homo sapiens] 127 2e-29
gi|24308065 netrin 5 [Homo sapiens] 122 6e-28
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 96 1e-19
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 96 1e-19
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 88 2e-17
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 88 2e-17
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 87 5e-17
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 84 2e-16
>gi|164414431 netrin G1 isoform 1 [Homo sapiens]
Length = 539
Score = 1174 bits (3037), Expect = 0.0
Identities = 539/539 (100%), Positives = 539/539 (100%)
Query: 1 MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY 60
MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY
Sbjct: 1 MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY 60
Query: 61 LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS 120
LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS
Sbjct: 61 LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS 120
Query: 121 ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT 180
ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT
Sbjct: 121 ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT 180
Query: 181 DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM 240
DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM
Sbjct: 181 DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM 240
Query: 241 ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN 300
ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN
Sbjct: 241 ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN 300
Query: 301 LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS
Sbjct: 301 LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
Query: 361 IGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIEC 420
IGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIEC
Sbjct: 361 IGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIEC 420
Query: 421 YCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTC 480
YCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTC
Sbjct: 421 YCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTC 480
Query: 481 HNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGSPALLLLTTLLGTASPLVF 539
HNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGSPALLLLTTLLGTASPLVF
Sbjct: 481 HNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGSPALLLLTTLLGTASPLVF 539
>gi|164414437 netrin G1 isoform 2 [Homo sapiens]
Length = 480
Score = 829 bits (2141), Expect = 0.0
Identities = 420/551 (76%), Positives = 434/551 (78%), Gaps = 83/551 (15%)
Query: 1 MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY 60
MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY
Sbjct: 1 MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY 60
Query: 61 LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS 120
LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS
Sbjct: 61 LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS 120
Query: 121 ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT 180
ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT
Sbjct: 121 ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT 180
Query: 181 DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM 240
DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM
Sbjct: 181 DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM 240
Query: 241 ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN 300
ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN
Sbjct: 241 ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN 300
Query: 301 LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS
Sbjct: 301 LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
Query: 361 IGNCECFGHS-NRCSYIDL-----------LNTVICVSCKHNTRGQHCELCRLGYFRNAS 408
IGN F S +++ L+TV V ++ R C
Sbjct: 361 IGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVC------------ 408
Query: 409 AQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCD 468
D+E + +C G+ H+ C C TG C++
Sbjct: 409 ---DNELL----HCQNGGTCHNNVR----CLCPAAYTGILCEK----------------- 440
Query: 469 NELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGSPALLLLT 528
+RC EEAGSCGSDSGQGAPPHGSPALLLLT
Sbjct: 441 ---------------LRC----------------EEAGSCGSDSGQGAPPHGSPALLLLT 469
Query: 529 TLLGTASPLVF 539
TLLGTASPLVF
Sbjct: 470 TLLGTASPLVF 480
>gi|54312078 netrin G1 isoform 3 [Homo sapiens]
Length = 438
Score = 779 bits (2012), Expect = 0.0
Identities = 369/400 (92%), Positives = 371/400 (92%)
Query: 1 MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY 60
MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY
Sbjct: 1 MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY 60
Query: 61 LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS 120
LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS
Sbjct: 61 LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS 120
Query: 121 ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT 180
ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT
Sbjct: 121 ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT 180
Query: 181 DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM 240
DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM
Sbjct: 181 DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM 240
Query: 241 ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN 300
ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN
Sbjct: 241 ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN 300
Query: 301 LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS
Sbjct: 301 LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
Query: 361 IGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCR 400
IG C C + + C G CE R
Sbjct: 361 IGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLR 400
Score = 183 bits (465), Expect = 3e-46
Identities = 95/151 (62%), Positives = 100/151 (66%), Gaps = 22/151 (14%)
Query: 411 LDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDEC---LPGNSWHYG------ 461
+ D V C CN ++ N CEC+ TTGP C +C G W G
Sbjct: 288 ISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIP 347
Query: 462 ------CQP-------NVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSC 508
C P NVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSC
Sbjct: 348 KGTANTCIPSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSC 407
Query: 509 GSDSGQGAPPHGSPALLLLTTLLGTASPLVF 539
GSDSGQGAPPHGSPALLLLTTLLGTASPLVF
Sbjct: 408 GSDSGQGAPPHGSPALLLLTTLLGTASPLVF 438
>gi|190014607 netrin G2 [Homo sapiens]
Length = 530
Score = 691 bits (1782), Expect = 0.0
Identities = 311/519 (59%), Positives = 384/519 (73%), Gaps = 8/519 (1%)
Query: 24 PLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMG 83
PL G YD+CK+ + T+EG W++ ACQP+ + Y+KVK++P ITCGDPPE FC+
Sbjct: 13 PLASGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGITCGDPPERFCSHE 72
Query: 84 NPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIE 143
NPY+C+NECDAS P+LAHPP LMFD E +T+WQS TW YP PL+ NITLSW+KT+E
Sbjct: 73 NPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVE 132
Query: 144 LTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLE 203
LTD++V+TFE GRP M+LEKSLD GRTWQPYQ+YA DC++AF M + +D+S +
Sbjct: 133 LTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSSSSAHR 192
Query: 204 IICTEEYST-GYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDL 262
++CTEEYS + K + FE++DRFA FAGP LRNM +LY +L++ K L++FFT+TDL
Sbjct: 193 VLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDL 252
Query: 263 RIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTT 322
R+RLLRPA+G +V +L +YFYAIS+I+V GRCKCNLHA +C L CECEHNTT
Sbjct: 253 RMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMREGSLQCECEHNTT 312
Query: 323 GPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTV 382
GPDCGKCKKN++ R W GSYLP+P G+ N C + S GNCEC+GHSNRCSYID LN V
Sbjct: 313 GPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC-ATAGSFGNCECYGHSNRCSYIDFLNVV 371
Query: 383 ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKT 442
CVSCKHNTRGQHC+ CRLGY+RN SA+LDDENVCIEC CN +GS+HDRCN +GFCEC+
Sbjct: 372 TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECRE 431
Query: 443 GTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRC 502
G GPKCD+CLP + W GC PNVCD++ L CQNGGTC N RC CP YTG+ CE+ RC
Sbjct: 432 GAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRC 491
Query: 503 EEA---GSCGSDSGQGAPPHGSPALLL-LTTLLGTASPL 537
+ A G D GA P PA LL LLG A+ L
Sbjct: 492 DPADDDGGLDCDRAPGAAPR--PATLLGCLLLLGLAARL 528
>gi|148613884 netrin 1 [Homo sapiens]
Length = 604
Score = 241 bits (616), Expect = 9e-64
Identities = 136/401 (33%), Positives = 203/401 (50%), Gaps = 45/401 (11%)
Query: 71 TCGDPPETFCAMGNP----YMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEY 126
TCG PP +C + + C+AS P+ AHPP + D H T WQS + ++
Sbjct: 69 TCGRPPARYCVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQF 128
Query: 127 PKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF 186
P V +TLS K E+T + + F S RP+ M + KS+DYGRTW P+Q+Y+T C +
Sbjct: 129 PH--NVTLTLSLGKKFEVT-YVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMY 185
Query: 187 HMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQ 246
+ ++ +++ E +CT+ ++ + +I F D P +
Sbjct: 186 NRPHRA--PITKQNEQEAVCTDSHTDMRPLSGGLIAFSTLD-----GRPSAHDF------ 232
Query: 247 LDTTKKLRDFFTVTDLRIRLLR-PAVGEIFVDELHLAR--YFYAISDIKVRGRCKCNLHA 303
D + L+D+ T TD+R+ R G+ D+ LAR YFYA+SD++V GRCKCN HA
Sbjct: 233 -DNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHA 291
Query: 304 TVCVYD-NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIG 362
CV D + L C+C HNT GP+C +CK + RPW + AN C+
Sbjct: 292 ARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRAT-----AREANECVA------ 340
Query: 363 NCECFGHSNRCSYIDLLNTV-------ICVSCKHNTRGQHCELCRLGYFRNASAQLDDEN 415
C C H+ RC + L + +C++C+HNT G+HC C+ GY+R+ +
Sbjct: 341 -CNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRK 399
Query: 416 VCIECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPG 455
C C C+P+G+ CN +G C CK G TG C+ C G
Sbjct: 400 ACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKG 440
Score = 32.7 bits (73), Expect = 0.86
Identities = 20/78 (25%), Positives = 28/78 (35%), Gaps = 4/78 (5%)
Query: 294 RGRCK-CNLHATVCVYDNSKLT---CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKG 349
R CK C+ H T C C+ TG C +C K YQ + IP
Sbjct: 398 RKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVA 457
Query: 350 TANTCIPSISSIGNCECF 367
T S+ +C+ +
Sbjct: 458 PPTTAASSVEEPEDCDSY 475
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 224 bits (572), Expect = 1e-58
Identities = 144/451 (31%), Positives = 206/451 (45%), Gaps = 60/451 (13%)
Query: 71 TCGDPPETFCAM----GNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWK-- 124
TCG PPE +C G C+ CDA P L H + D+ + +T+WQS T
Sbjct: 68 TCGTPPEEYCVQTGVTGVTKSCHL-CDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAG 126
Query: 125 -EYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCL 183
+YP +N+TL K ++T + + F + RP+ + K W PYQYY+ C
Sbjct: 127 VQYPS--SINLTLHLGKAFDIT-YVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCE 183
Query: 184 DAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASL 243
+ + + + +CT+E+S + F L S
Sbjct: 184 NTYSKANRGFIRTGGDEQ-QALCTDEFSDISPLTGGNVAFST-----------LEGRPSA 231
Query: 244 YGQLDTTKKLRDFFTVTDLRIRL--LRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNL 301
Y D + L+++ T TD+R+ L L E+F D L Y+YAISD V GRCKCN
Sbjct: 232 YN-FDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNG 290
Query: 302 HATVCVYDN-SKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
HA+ C+ + KL C C+HNT G DC KC + RPW + +A+ C+P
Sbjct: 291 HASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRAT-----AESASECLP---- 341
Query: 361 IGNCECFGHSNRCSYIDLLNTVI-----CVSCKHNTRGQHCELCRLGYFRNASAQLDDEN 415
C+C G S C + L C +C+ NT G HCE CR +FR L +
Sbjct: 342 ---CDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFR-----LGNNE 393
Query: 416 VCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPG--NSWHYGCQPNVCDNELLH 473
C C+C+P+GS+ +C+ G C CK G G KCD C PG + GC+P CD
Sbjct: 394 ACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCD----- 448
Query: 474 CQNGGTCHNNV---RCLCPAAYTGILCEKLR 501
+G N+ RC+C G CE+ +
Sbjct: 449 -PSGSIDECNIETGRCVCKDNVEGFNCERCK 478
Score = 86.7 bits (213), Expect = 5e-17
Identities = 75/269 (27%), Positives = 93/269 (34%), Gaps = 85/269 (31%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
C CN H+ C D C C NT GP C KC Y G + GT++ C P
Sbjct: 724 CACNGHSETC--DPETGVCNCRDNTAGPHCEKCSDGYYGDSTA---------GTSSDCQP 772
Query: 357 SISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYF-----RNASAQL 411
C C G S+ C+ + V+C +C T G+ CELC GYF RN +L
Sbjct: 773 -------CPCPGGSS-CAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRL 824
Query: 412 -----DDENV--------------CIECYCNPLGSIHDRCNG------------------ 434
+N+ C++C N G DRC
Sbjct: 825 CRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKAC 884
Query: 435 -----------------SGFCECKTGTTGPKCDECLPG---NSWHYGCQPNVCDNELLHC 474
+G CEC TG C C PG GC+ CD L
Sbjct: 885 NCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCER--CDCHALGS 942
Query: 475 QNGGTCHNNVRCLCPAAYTGILCEKLRCE 503
NG +C C TG CE RCE
Sbjct: 943 TNGQCDIRTGQCECQPGITGQHCE--RCE 969
Score = 74.7 bits (182), Expect = 2e-13
Identities = 52/174 (29%), Positives = 69/174 (39%), Gaps = 35/174 (20%)
Query: 297 CKCNLHATVCVYDNSKLT---CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANT 353
C CNL+ T+ + CEC + TG DCG C PG Y
Sbjct: 884 CNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGAC---------DPGFYN--------- 925
Query: 354 CIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDD 413
+ S C+C + D+ T C C+ GQHCE C + +F
Sbjct: 926 -LQSGQGCERCDCHALGSTNGQCDI-RTGQC-ECQPGITGQHCERCEVNHFGFGPEG--- 979
Query: 414 ENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDEC----LPGNSWHYGCQ 463
C C C+P GS+ +C G CEC+ G G +CD+C SW GCQ
Sbjct: 980 ---CKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWP-GCQ 1029
Score = 61.2 bits (147), Expect = 2e-09
Identities = 57/211 (27%), Positives = 84/211 (39%), Gaps = 53/211 (25%)
Query: 314 TCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRC 373
+C C G C C Y+ + G Y P C+ C C GHS C
Sbjct: 689 SCTCPVGYGGQFCEMCLSGYRRETPNLGPYSP--------CV-------LCACNGHSETC 733
Query: 374 SYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGS---IHD 430
T +C +C+ NT G HCE C GY+ +++A + C C C P GS +
Sbjct: 734 D----PETGVC-NCRDNTAGPHCEKCSDGYYGDSTAGTSSD--CQPCPC-PGGSSCAVVP 785
Query: 431 RCNGSGFCECKTGTTGPKCDECLPGNSWHYG----------------CQPNVCDNELLHC 474
+ C TGTTG +C+ C G ++G C N+ N + +C
Sbjct: 786 KTKEVVCTNCPTGTTGKRCELCDDG---YFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNC 842
Query: 475 QN-GGTCHNNVRCLCPAAYTGILCEKLRCEE 504
G C ++C+ A G C+ RC++
Sbjct: 843 NRLTGEC---LKCIYNTA--GFYCD--RCKD 866
Score = 57.4 bits (137), Expect = 3e-08
Identities = 45/147 (30%), Positives = 59/147 (40%), Gaps = 31/147 (21%)
Query: 386 SCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTT 445
+C GQ CE+C GY R + L + C+ C CN D +G C C+ T
Sbjct: 691 TCPVGYGGQFCEMCLSGY-RRETPNLGPYSPCVLCACNGHSETCD--PETGVCNCRDNTA 747
Query: 446 GPKCDECLPGNSWHYG---------CQPNVCDNELLHCQNGGTC-----HNNVRCL-CPA 490
GP C++C G +YG CQP C G +C V C CP
Sbjct: 748 GPHCEKCSDG---YYGDSTAGTSSDCQP-------CPCPGGSSCAVVPKTKEVVCTNCPT 797
Query: 491 AYTGILCEKLRCEEAGSCGSDSGQGAP 517
TG CE C++ G G G+ P
Sbjct: 798 GTTGKRCE--LCDD-GYFGDPLGRNGP 821
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 212 bits (540), Expect = 6e-55
Identities = 146/449 (32%), Positives = 206/449 (45%), Gaps = 56/449 (12%)
Query: 71 TCGDPPETFC----AMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWK-- 124
TCG PPE FC A G C CDA+ P+ H + DF + ST+WQS +
Sbjct: 53 TCGSPPEDFCPHVGAAGAGAHCQR-CDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFG 111
Query: 125 -EYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCL 183
+YP VNITL K E+T + + F + RP+ + K W+PYQ+Y+ C
Sbjct: 112 VQYPT--SVNITLRLGKAYEIT-YVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQ 168
Query: 184 DAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASL 243
+ P+ CT E+S + + F L S
Sbjct: 169 KTYGR-PEGQYLRPGEDERVAFCTSEFSDISPLSGGNVAFST-----------LEGRPSA 216
Query: 244 YGQLDTTKKLRDFFTVTDLRIRL--LRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNL 301
Y + + L+++ T T+L I L L +IF D L Y+YA+SD V GRCKCN
Sbjct: 217 YN-FEESPGLQEWVTSTELLISLDRLNTFGDDIFKDPKVLQSYYYAVSDFSVGGRCKCNG 275
Query: 302 HATVCVYDNS-KLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
HA+ C D + +L C C+HNTTG DC +C +Q RPW+ G+ A+ C+P
Sbjct: 276 HASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGT-----AEAAHECLP---- 326
Query: 361 IGNCECFGHSNRCSYI-DLLNTV----ICVSCKHNTRGQHCELCRLGYFRNASAQLDDEN 415
C C G S C++ +L + C C+ +T G HCE C+ ++ D
Sbjct: 327 ---CNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYH-----WDPRM 378
Query: 416 VCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPG--NSWHYGCQPNVCDNELLH 473
C C C GS+H +C+ +G C CK TG KCD CLPG + GC+P C+
Sbjct: 379 PCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCN----P 434
Query: 474 CQNGGTCH-NNVRCLCPAAYTGILCEKLR 501
+ TC + RC C G LC++ R
Sbjct: 435 AGSLDTCDPRSGRCPCKENVEGNLCDRCR 463
Score = 87.4 bits (215), Expect = 3e-17
Identities = 74/303 (24%), Positives = 98/303 (32%), Gaps = 105/303 (34%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSY----LPIPKGTAN 352
C CN H T D + C C H+T GP C +C + G P++ + P P +A
Sbjct: 707 CTCNQHGTC---DPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSAC 763
Query: 353 TCIPSISSIGNCEC-----------------------FGHSNRCSYIDLLNTVI------ 383
T IP + C FGH C V
Sbjct: 764 TTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGN 823
Query: 384 -------CVSCKHNTRGQHCELCRLGYFRNASA--------------------------- 409
C+ C HNT G HCE C+ G++ +A A
Sbjct: 824 CDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPV 883
Query: 410 -----------------------QLDDENVCIECYCNPLGSIHDRCNG-SGFCECKTGTT 445
L C C C+PLGS D+C+ +G C C+ G T
Sbjct: 884 TGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVT 943
Query: 446 GPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGT----CHNNVRCLCPAAYTGILCEKLR 501
G CD C G +G C C G CH N C+C + G C+ R
Sbjct: 944 GQACDRCQLG---FFGFSIKGC--RACRCSPLGAASAQCHENGTCVCRPGFEGYKCD--R 996
Query: 502 CEE 504
C +
Sbjct: 997 CHD 999
Score = 56.6 bits (135), Expect = 6e-08
Identities = 66/274 (24%), Positives = 87/274 (31%), Gaps = 85/274 (31%)
Query: 315 CECEHNTTGPDCGKCKKNY-----QGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGH 369
C C TG C C Y QG P++ S +P TC P+ G C C H
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYA--SCVPCTCNQHGTCDPNT---GICVCSHH 727
Query: 370 S--------------------------------NRCSYIDLLNTVICVSCKHNTRGQHCE 397
+ + C+ I V+C C RG+ CE
Sbjct: 728 TEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCE 787
Query: 398 LCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNG-----SGFC-ECKTGTTGPKCDE 451
+C G+F + C +C C+ G++ G SG C C TTG C+
Sbjct: 788 VCDDGFFGDPLGLFGHPQPCHQCQCS--GNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEH 845
Query: 452 CLPGNSWHYG---------------CQPNVCDNELLHCQN-GGTC----HNNVRCLCPAA 491
C G YG C P +E + C G C H R C
Sbjct: 846 CQEG---FYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARD-CSRC 901
Query: 492 YTGIL-------CEKLRCEEAGS----CGSDSGQ 514
Y G C +C GS C +GQ
Sbjct: 902 YPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQ 935
>gi|5453810 netrin 3 [Homo sapiens]
Length = 580
Score = 199 bits (505), Expect = 7e-51
Identities = 127/395 (32%), Positives = 184/395 (46%), Gaps = 52/395 (13%)
Query: 71 TCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPL 130
TCG P CDAS P AH P L+ G W+S + PL
Sbjct: 58 TCGRP------------ATRACDASDPRRAHSPALLTSPGGTASPLCWRSESLPR--APL 103
Query: 131 QVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDC-LDAFHMD 189
V +T+ K EL + + F S P + L KS D+GR+W P ++++ C LD +
Sbjct: 104 NVTLTVPLGKAFELVF-VSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLP 162
Query: 190 PKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDT 249
+ E +C S ++ F ++D + P L LD+
Sbjct: 163 APANGPAGPGP--EALCFPA-PLAQPDGSGLLAFSMQDS----SPPGL--------DLDS 207
Query: 250 TKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATVCVYD 309
+ L+D+ T TD+R+ L RP+ D + Y YA +D++V GRCKCN HA+ C+ D
Sbjct: 208 SPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVVPYSYAATDLQVGGRCKCNGHASRCLLD 267
Query: 310 NS-KLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFG 368
L C+C H T GPDCG+CK Y RPW + ++ C+ C C G
Sbjct: 268 TQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRAT-----ARESHACLA-------CSCNG 315
Query: 369 HSNRCSYIDLLNTV-------ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECY 421
H+ RC + L + +C++C+HNT G+HC CR G++R+ L D C C
Sbjct: 316 HARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACD 375
Query: 422 CNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPG 455
C+P+G+ CN +G C CK G TG C+ C PG
Sbjct: 376 CHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPG 410
Score = 29.3 bits (64), Expect = 9.5
Identities = 19/70 (27%), Positives = 31/70 (44%), Gaps = 3/70 (4%)
Query: 287 AISDIKVRGRCKCN-LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQ--GRPWSPGSY 343
A+SD + C C+ + A + + C C+ TG C +C +Q P +P
Sbjct: 364 ALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVK 423
Query: 344 LPIPKGTANT 353
PIP T ++
Sbjct: 424 TPIPGPTEDS 433
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 187 bits (476), Expect = 2e-47
Identities = 129/461 (27%), Positives = 211/461 (45%), Gaps = 91/461 (19%)
Query: 43 KVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHP 102
K+W C +T++ + + D+TC P C+ +C+A+ P LAH
Sbjct: 46 KLWADTTCGQNATELYCFYS---ENTDLTCRQPK-----------CD-KCNAAYPHLAHL 90
Query: 103 PELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMIL 162
P M D R P T+WQSA + + +Q+++ + T ++++ F+S RP M+L
Sbjct: 91 PSAMADSSFRFPRTWWQSAE-DVHREKIQLDLEAEFYFT-----HLIVMFKSPRPAAMVL 144
Query: 163 EKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIH 222
++S D+G+TW+PY+Y+AT+C F ++ VK + ICT +YS+ + +
Sbjct: 145 DRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKGA-------ICTSKYSSPFPCTGGEVI 197
Query: 223 FEIKDRFAFFAGPRLRNMASLYGQLDT----TKKLRDFFTVTDLRIRLLRPAVGEIFVDE 278
F+ +L DT + K+++ +T+LR++LL+ ++
Sbjct: 198 FK-----------------ALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRND 240
Query: 279 LHLA-RYF--YAISDIKVRGRCKCNLHATVCV-------------YDNSKLTCECEHNTT 322
L+ ++F YAI D V+G C CN HA C+ + C C+HNT
Sbjct: 241 LNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTA 300
Query: 323 GPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSY-IDLLNT 381
G C C Y RPW G N C C+C GH++ C + +++
Sbjct: 301 GSHCQHCAPLYNDRPWEAADG---KTGAPNEC-------RTCKCNGHADTCHFDVNVWEA 350
Query: 382 V------ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGS 435
+C C+HNT GQ+C+ C+ G++R+ + C C C+P+GS N
Sbjct: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
Query: 436 GFCE-------CKTGTTGPKCDECLPG--NSWHYGCQPNVC 467
FC+ CK G G +CD C+ G YGC+P C
Sbjct: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC 451
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 187 bits (476), Expect = 2e-47
Identities = 137/488 (28%), Positives = 215/488 (44%), Gaps = 84/488 (17%)
Query: 58 TKYLKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTF 117
T+ L KL + GDP +T C+ C A+ AHP D R +
Sbjct: 77 TEDLYCKLVGGPVAGGDPNQTIRGQ----YCDI-CTAANSNKAHPASNAIDGTER----W 127
Query: 118 WQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQY 177
WQS + +VN+TL + + ++ S RPD +LE+S+D+GRT+QP+Q+
Sbjct: 128 WQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQF 187
Query: 178 YAT---DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAG 234
+A+ DCL+ F P++++ +++ ICT EY S+I+ E +
Sbjct: 188 FASSKRDCLERF--GPQTLERITRDDA--AICTTEY-------SRIVPLENGEIVVSLVN 236
Query: 235 PRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRP------AVGEIFVDELHLARYFYAI 288
R M Y L LR+F T++R+R LR +G+ D RY+Y+I
Sbjct: 237 GRPGAMNFSYSPL-----LREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSI 291
Query: 289 SDIKVRGRCKCNLHATVC----VYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYL 344
DI + GRC C+ HA C D +L C C+HNT G C +C + +PW P +
Sbjct: 292 KDISIGGRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPAT-- 349
Query: 345 PIPKGTANTCIPSISSIGNCECFGHSNRCSY---IDLLNTV-----------ICVSCKHN 390
+AN C +C C+GH+ C Y +D +C+ C+H+
Sbjct: 350 ---ANSANEC-------QSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHH 399
Query: 391 TRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCD 450
T G +CE C G++R+ + LD +VC C C + + +G C C+ +G +CD
Sbjct: 400 TTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCD 459
Query: 451 ECLPGNSWHYGCQPNVCDN-----------ELLHCQ------NGGTCHNNV---RCLCPA 490
C G + C P + ++++C G C + RCLC
Sbjct: 460 VCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKP 519
Query: 491 AYTGILCE 498
+ G CE
Sbjct: 520 NFQGTHCE 527
Score = 84.0 bits (206), Expect = 3e-16
Identities = 53/164 (32%), Positives = 71/164 (43%), Gaps = 34/164 (20%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCS 374
C C + G C +C +PG Y + C+P C+C GHS+RC
Sbjct: 1831 CLCPASYRGDSCQEC---------APGFYRDVKGLFLGRCVP-------CQCHGHSDRC- 1873
Query: 375 YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCN---PLGSIHDR 431
L + +CV C+HNT G HCE C+ G+ S++ D C+ C C P + +
Sbjct: 1874 ---LPGSGVCVDCQHNTEGAHCERCQAGF---VSSRDDPSAPCVSCPCPLSVPSNNFAEG 1927
Query: 432 C---NGSGFCECKTGTTGPKCDECLP---GNSWHYG--CQPNVC 467
C G C CK G G C+ C P GN G CQP C
Sbjct: 1928 CVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDC 1971
Score = 80.5 bits (197), Expect = 4e-15
Identities = 70/244 (28%), Positives = 96/244 (39%), Gaps = 52/244 (21%)
Query: 300 NLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSIS 359
N A CV + C C+ G C +C + G P GS +C P
Sbjct: 1922 NNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGS----------SCQP--- 1968
Query: 360 SIGNCECFGHSNR---CSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENV 416
C+C G+ + S D L T C C +T G CE+C G++ NA
Sbjct: 1969 ----CDCSGNGDPNLLFSDCDPL-TGACRGCLRHTTGPRCEICAPGFYGNALL----PGN 2019
Query: 417 CIECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPGNSWHY------GCQPNVC-- 467
C C C P G+ + C+ SG C CK G TG +CD C G H+ GC+P C
Sbjct: 2020 CTRCDCTPCGT--EACDPHSGHCLCKAGVTGRRCDRCQEG---HFGFDGCGGCRPCACGP 2074
Query: 468 --DNELLHCQNGGTCHNNVRCL------CPAAYTGIL---CEKLRCEEAGSCGSDSGQGA 516
+ H Q+ G CH + C Y G+ C + +C G C +G+
Sbjct: 2075 AAEGSECHPQS-GQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC-PGGRCDPHTGRCN 2132
Query: 517 PPHG 520
P G
Sbjct: 2133 CPPG 2136
Score = 77.8 bits (190), Expect = 2e-14
Identities = 63/243 (25%), Positives = 86/243 (35%), Gaps = 59/243 (24%)
Query: 295 GRCKCN-----LHATVCV---YDNSKLTCECEH-----NTTGPDCG--KCKKNYQGRPWS 339
GRC C H +C Y C+C + PD G +C+ ++G
Sbjct: 513 GRCLCKPNFQGTHCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEG---- 568
Query: 340 PGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELC 399
T + C P C+ G S + + + C+ G HC+ C
Sbjct: 569 ---------ATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRC 619
Query: 400 RLGY--FRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNS 457
R GY F N C C C+P G++ C G C C+ G TG C EC PG
Sbjct: 620 RPGYHGFPN----------CQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFH 669
Query: 458 WHYGCQPNVCDNELLHCQNGGTCH-----NNVRCLCPAAYTGILCE-------KLRCEEA 505
C P HC G+ H + +C C TG+ C+ EA
Sbjct: 670 GFPSCVP-------CHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEA 722
Query: 506 GSC 508
GSC
Sbjct: 723 GSC 725
Score = 77.0 bits (188), Expect = 4e-14
Identities = 56/184 (30%), Positives = 71/184 (38%), Gaps = 36/184 (19%)
Query: 317 CEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYI 376
C +TTGP C C + G PG+ T C P G C HS C
Sbjct: 1994 CLRHTTGPRCEICAPGFYGNALLPGNC------TRCDCTPC----GTEACDPHSGHCL-- 2041
Query: 377 DLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSG 436
CK G+ C+ C+ G+F D C C C P + SG
Sbjct: 2042 ----------CKAGVTGRRCDRCQEGHFG-----FDGCGGCRPCACGPAAEGSECHPQSG 2086
Query: 437 FCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQ-NGGTCHNNV-RCLCPAAYTG 494
C C+ GT GP+C EC PG ++G C CQ GG C + RC CP +G
Sbjct: 2087 QCHCRPGTMGPQCRECAPG---YWGLPEQGC----RRCQCPGGRCDPHTGRCNCPPGLSG 2139
Query: 495 ILCE 498
C+
Sbjct: 2140 ERCD 2143
Score = 56.6 bits (135), Expect = 6e-08
Identities = 39/143 (27%), Positives = 59/143 (41%), Gaps = 23/143 (16%)
Query: 311 SKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGN-CECFGH 369
+++ C C + GP C +CK + G SP + P+G ++G EC
Sbjct: 740 AQVPCMCRAHVEGPSCDRCKPGFWGL--SPSN----PEGCTRCSCDLRGTLGGVAECQPG 793
Query: 370 SNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIH 429
+ +C CK + GQ C C+ G+F A D C C C+ G++
Sbjct: 794 TGQCF------------CKPHVCGQACASCKDGFFGLDQA---DYFGCRSCRCDIGGALG 838
Query: 430 DRCNG-SGFCECKTGTTGPKCDE 451
C +G C C+ T GP C E
Sbjct: 839 QSCEPRTGVCRCRPNTQGPTCSE 861
Score = 55.5 bits (132), Expect = 1e-07
Identities = 43/170 (25%), Positives = 61/170 (35%), Gaps = 29/170 (17%)
Query: 299 CNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSI 358
C+ A +C D C C T PDC C+ P + G + + N P I
Sbjct: 1484 CDCGARLC--DELTGQCICPPRTIPPDCLLCQ------PQTFGCHPLVGCEECNCSGPGI 1535
Query: 359 SSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCI 418
+ + C S +C C+ N G+ C+ C G+ C
Sbjct: 1536 QELTDPTCDTDSGQCK------------CRPNVTGRRCDTCSPGFHGYPR--------CR 1575
Query: 419 ECYCNPLGSIHDRCNG-SGFCECKTGTTGPKCDECLPGNSWHYGCQPNVC 467
C C+ G+ C+ +G C CK GPKCD+C G P C
Sbjct: 1576 PCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGC 1625
Score = 49.3 bits (116), Expect = 9e-06
Identities = 56/215 (26%), Positives = 74/215 (34%), Gaps = 56/215 (26%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCS 374
C C + G DC +C Y G P C P C+C + C
Sbjct: 1457 CPCHAHVIGRDCSRCATGYWGFP---------------NCRP-------CDC--GARLCD 1492
Query: 375 YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGS---IHDR 431
+ T C+ C T C LC+ F C EC C+ G
Sbjct: 1493 EL----TGQCI-CPPRTIPPDCLLCQPQTFGCHPLV-----GCEECNCSGPGIQELTDPT 1542
Query: 432 CN-GSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHN-----NVR 485
C+ SG C+C+ TG +CD C PG + C+P CD C GT +
Sbjct: 1543 CDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRP--CD-----CHEAGTAPGVCDPLTGQ 1595
Query: 486 CLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHG 520
C C G C++ S G+ S A P G
Sbjct: 1596 CYCKENVQGPKCDQC------SLGTFSLDAANPKG 1624
Score = 49.3 bits (116), Expect = 9e-06
Identities = 49/187 (26%), Positives = 67/187 (35%), Gaps = 46/187 (24%)
Query: 296 RCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
RC C T +S C C+ TG C +C++ + G G C
Sbjct: 2022 RCDCTPCGTEACDPHSG-HCLCKAGVTGRRCDRCQEGHFGFDGCGG---------CRPCA 2071
Query: 356 PSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDEN 415
++ G+ EC S +C C+ T G C C GY+ E
Sbjct: 2072 CGPAAEGS-ECHPQSGQCH------------CRPGTMGPQCRECAPGYWGLP------EQ 2112
Query: 416 VCIECYCNPLGSIHDRCNG-SGFCECKTGTTGPKCDEC-------LPGNSWHYGCQPNVC 467
C C C P G RC+ +G C C G +G +CD C +PG + VC
Sbjct: 2113 GCRRCQC-PGG----RCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVC 2167
Query: 468 DNELLHC 474
D HC
Sbjct: 2168 D----HC 2170
Score = 46.6 bits (109), Expect = 6e-05
Identities = 35/130 (26%), Positives = 51/130 (39%), Gaps = 16/130 (12%)
Query: 380 NTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRC-NGSGFC 438
N +C+ C + RG C+ C G++R+ C+ C C+ DRC GSG C
Sbjct: 1827 NVELCL-CPASYRGDSCQECAPGFYRDVKGLFLGR--CVPCQCH---GHSDRCLPGSGVC 1880
Query: 439 -ECKTGTTGPKCDECLPG-----NSWHYGCQPNVCDNELLHCQNGGTC---HNNVRCLCP 489
+C+ T G C+ C G + C C + C +CLC
Sbjct: 1881 VDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCK 1940
Query: 490 AAYTGILCEK 499
Y G CE+
Sbjct: 1941 PGYAGASCER 1950
Score = 46.2 bits (108), Expect = 8e-05
Identities = 62/287 (21%), Positives = 84/287 (29%), Gaps = 109/287 (37%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
C C+ T+ + C C+ GP C +C+ Y G P A TC P
Sbjct: 587 CGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHG----------FPNCQACTCDP 636
Query: 357 SISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENV 416
+ C G +C C+ G C+ C G+ S
Sbjct: 637 RGALDQLCGAGG--------------LC-RCRPGYTGTACQECSPGFHGFPS-------- 673
Query: 417 CIECYCNPLGSIHDRCNG-SGFCECKTGTTG----------------------------- 446
C+ C+C+ GS+H C+ SG C C+ TG
Sbjct: 674 CVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPV 733
Query: 447 -------------------PKCDECLPG-----NSWHYGCQPNVCD-----NELLHCQNG 477
P CD C PG S GC CD + CQ G
Sbjct: 734 DPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPG 793
Query: 478 ---------------GTCHNNVRCLCPAAYTGILCEKLRCEEAGSCG 509
+C + L A Y G C RC+ G+ G
Sbjct: 794 TGQCFCKPHVCGQACASCKDGFFGLDQADYFG--CRSCRCDIGGALG 838
Score = 38.5 bits (88), Expect = 0.016
Identities = 34/138 (24%), Positives = 47/138 (34%), Gaps = 33/138 (23%)
Query: 403 YFRNASAQLD--DENVCIECYCNPLGSIHDRCNG-SGFCECKTGTTGPKCDECLPGNSWH 459
+ RNA+A L N C C+ +G+ C G C C G C C G
Sbjct: 1419 FCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGF 1478
Query: 460 YGCQPNVCDNELLHCQNGGTCHNNVRCLCP----------------AAYTGILCEKLRCE 503
C+P C L G +C+CP + + CE+ C
Sbjct: 1479 PNCRPCDCGARLCDELTG-------QCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCS 1531
Query: 504 EAG-------SCGSDSGQ 514
G +C +DSGQ
Sbjct: 1532 GPGIQELTDPTCDTDSGQ 1549
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 180 bits (457), Expect = 3e-45
Identities = 147/513 (28%), Positives = 230/513 (44%), Gaps = 113/513 (22%)
Query: 49 ACQPESTDMTKYLKVKLDPPDITCG-DPPETFCAMGNPYMCNNE----CDASTP------ 97
AC P + D+ +L TCG + +C + Y+ + CD+ P
Sbjct: 27 ACHPTTGDLLVGRNTQLMASS-TCGLSRAQKYCILS--YLEGEQKCFICDSRFPYDPYDQ 83
Query: 98 ELAHPPE-LMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGR 156
+H E ++ FE +WQS ++ V+I L + ++++TF++ R
Sbjct: 84 PNSHTIENVIVSFEPDREKKWWQSENGLDH-----VSIRLDLEALFRFS-HLILTFKTFR 137
Query: 157 PDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYS----- 211
P M++E+S DYG W+ ++Y+A DC +F ++ V +I+C +YS
Sbjct: 138 PAAMLVERSTDYGHNWKVFKYFAKDCATSF----PNITSGQAQGVGDIVCDSKYSDIEPS 193
Query: 212 TGYTTNSKIIH--FEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLR- 268
TG K++ FEI++ ++ + ++D T+T+LRI +
Sbjct: 194 TGGEVVLKVLDPSFEIENPYSPY--------------------IQDLVTLTNLRINFTKL 233
Query: 269 PAVGEIFVDELH---LARYFYAISDIKVRGRCKCNLHATVC---------VYDNSKLT-- 314
+G+ + L +Y+YA+ ++ VRG C CN HA+ C V+ +
Sbjct: 234 HTLGDALLGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHG 293
Query: 315 -CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRC 373
C C+HNT GP+C +CK +Q PW P + L N C +C C HS+RC
Sbjct: 294 QCVCQHNTDGPNCERCKDFFQDAPWRPAADLQ-----DNAC-------RSCSCNSHSSRC 341
Query: 374 SYIDL--------LNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPL 425
+ D+ L+ +C C+HNT GQHC+ CR ++R+ + D CI C C+P
Sbjct: 342 HF-DMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPD 400
Query: 426 GSI--------HDRCNGS--GFCECKTGTTGPKCDECLPGNSWHY--------GCQPNVC 467
G+I D GS G C CK G KCD+C P HY GCQP C
Sbjct: 401 GTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPN---HYGLSATDPLGCQP--C 455
Query: 468 DNELLHCQNGGTCH-NNVRCLCPAAYTGILCEK 499
D L TC + +CLC + TG CE+
Sbjct: 456 DCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE 488
Score = 72.8 bits (177), Expect = 8e-13
Identities = 59/217 (27%), Positives = 83/217 (38%), Gaps = 56/217 (25%)
Query: 310 NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGH 369
+S + C C TG CG+C + G P G+ C P C C +
Sbjct: 933 SSDVICNCLQGYTGTQCGECSTGFYGNPRISGA----------PCQP-------CACNNN 975
Query: 370 SN-----RCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNP 424
+ CS + T C+ C HNT+G +C+LC+ G++ +A Q C C C+
Sbjct: 976 IDVTDPESCSRV----TGECLRCLHNTQGANCQLCKPGHYGSALNQ-----TCRRCSCHA 1026
Query: 425 LGSIHDRCNG----------SGFCECKTGTTGPKCDECLPGNSWHY----GCQPNVCD-- 468
G C +G C C TG CD C G W+ GCQ CD
Sbjct: 1027 SGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADG-YWNLVPGRGCQSCDCDPR 1085
Query: 469 -NELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEE 504
++ HC +C C Y G C + C+E
Sbjct: 1086 TSQSSHCD-----QLTGQCPCKLGYGGKRCSE--CQE 1115
Score = 67.0 bits (162), Expect = 4e-11
Identities = 54/208 (25%), Positives = 84/208 (40%), Gaps = 52/208 (25%)
Query: 297 CKCNLHATVCVYDN-SKLTCECE---HNTTGPDCGKCKKNYQGR---------------- 336
C CN + V ++ S++T EC HNT G +C CK + G
Sbjct: 970 CACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGV 1029
Query: 337 -----PWSPGSYLPIPKGTANTCIPSISSIG------------------NCECFGHSNRC 373
P G+ L P A C+P+++ + +C+C +++
Sbjct: 1030 SPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQS 1089
Query: 374 SYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCN 433
S+ D L T C CK G+ C C+ Y+ D CI C CN G+ C+
Sbjct: 1090 SHCDQL-TGQC-PCKLGYGGKRCSECQENYYG------DPPGRCIPCDCNRAGTQKPICD 1141
Query: 434 -GSGFCECKTGTTGPKCDECLPGNSWHY 460
+G C C+ G +G +CD C G+S +
Sbjct: 1142 PDTGMCRCREGVSGQRCDRCARGHSQEF 1169
Score = 57.0 bits (136), Expect = 4e-08
Identities = 55/215 (25%), Positives = 84/215 (39%), Gaps = 60/215 (27%)
Query: 297 CKCNLHATVCVYDNSKL---------TCE-CEHNTTGPDCGKCKKNYQGRPWS----PGS 342
C CN H++ C +D + CE C+HNT G C +C+ + P P +
Sbjct: 332 CSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYA 391
Query: 343 YLPI---PKGTAN--TCI----PSISSI-GNCEC----------------FGHSNR---- 372
+P P GT + C+ P++ S+ G C C +G S
Sbjct: 392 CIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLG 451
Query: 373 -----CSYIDLLNTVIC------VSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECY 421
C+ + L + C C G HCE C +GY+ + + C C
Sbjct: 452 CQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHL----HGCSPCD 507
Query: 422 CNPLGSIHDRCNG-SGFCECKTGTTGPKCDECLPG 455
C+ G+ + C+ +G CEC+ TG C E PG
Sbjct: 508 CDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPG 542
Score = 56.6 bits (135), Expect = 6e-08
Identities = 59/227 (25%), Positives = 82/227 (36%), Gaps = 54/227 (23%)
Query: 290 DIKVRGRCKCNLHA-----TVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYL 344
D+ G C+ H TVC D C C +G C +C Y G P
Sbjct: 808 DLGHHGCHPCHCHPQGSKDTVC--DQVTGQCPCHGEVSGRRCDRCLAGYFGFP------- 858
Query: 345 PIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYF 404
+C P C C NR + + T C +C T G++CE C GY+
Sbjct: 859 --------SCHP-------CPC----NRFAELCDPETGSCFNCGGFTTGRNCERCIDGYY 899
Query: 405 RNASAQLDDENVCIECYC--NPLGS-------IHDRCNGSGFCECKTGTTGPKCDECLPG 455
N S+ C C C +P + + + C C G TG +C EC G
Sbjct: 900 GNPSS----GQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTG 955
Query: 456 NSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRC 502
YG P + C C+NN+ P + + + E LRC
Sbjct: 956 ---FYG-NPRISGAPCQPC----ACNNNIDVTDPESCSRVTGECLRC 994
Score = 53.1 bits (126), Expect = 6e-07
Identities = 40/134 (29%), Positives = 53/134 (39%), Gaps = 15/134 (11%)
Query: 387 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNG-SGFCECKTGTT 445
CK G+ C+ C G + + C C+C+P GS C+ +G C C +
Sbjct: 790 CKPLVVGRCCDRCSTGSYDLG------HHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVS 843
Query: 446 GPKCDECLPGNSWHYGCQPNVCDNELLHCQ-NGGTCHNNVRCLCPAAYTGILCEKLRCEE 504
G +CD CL G C P C+ C G+C N C TG CE RC +
Sbjct: 844 GRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFN-----CGGFTTGRNCE--RCID 896
Query: 505 AGSCGSDSGQGAPP 518
SGQ P
Sbjct: 897 GYYGNPSSGQPCRP 910
Score = 50.1 bits (118), Expect = 5e-06
Identities = 44/132 (33%), Positives = 52/132 (39%), Gaps = 32/132 (24%)
Query: 408 SAQLDDENVCIECYCNPLGSIHDRCNG-SGFCECKTGTTGPKCDECLPG--NSWHYGCQP 464
SA+L D V C C+P GS+ C+ G C+CK G CD C G + H+GC P
Sbjct: 759 SAKLHDGAVA--CKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHP 816
Query: 465 ----------NVCDNELLHCQNGGTCHNNV---RC-LCPAAYTGI-LCEKLRCE------ 503
VCD C CH V RC C A Y G C C
Sbjct: 817 CHCHPQGSKDTVCDQVTGQC----PCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELC 872
Query: 504 --EAGSCGSDSG 513
E GSC + G
Sbjct: 873 DPETGSCFNCGG 884
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 176 bits (446), Expect = 5e-44
Identities = 138/495 (27%), Positives = 204/495 (41%), Gaps = 99/495 (20%)
Query: 71 TCGD--------PPETFC-------AMGNPYMCNNE----CDASTPELAHPPELMFDFEG 111
TCG+ PE +C A G+ + + C++ P AHP D
Sbjct: 65 TCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSE 124
Query: 112 RHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRT 171
R +WQS + +VN+TL + + ++ S RPD +LE+S+D+G T
Sbjct: 125 R----WWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGST 180
Query: 172 WQPYQYYA---TDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTT-NSKIIHFEIKD 227
+ P+QY+A DCL F + +++C EYS N +++ I
Sbjct: 181 YSPWQYFAHSKVDCLKEFGREANMAVTRDD----DVLCVTEYSRIVPLENGEVVVSLING 236
Query: 228 RFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRP------AVGEIFVDELHL 281
R P +N + LR+F T++R+R LR + + D
Sbjct: 237 R------PGAKNFTFSH-------TLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVT 283
Query: 282 ARYFYAISDIKVRGRCKCNLHATVCVYDNSK--LTCECEHNTTGPDCGKCKKNYQGRPWS 339
RY+Y+I DI + G+C CN HA VC +N + CEC+H+T G C +C Y R W
Sbjct: 284 RRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWR 343
Query: 340 PGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYID-------LLNTV-------ICV 385
P ++ + A C C GH++ C Y LNT +C+
Sbjct: 344 PAAWEQSHECEA------------CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCI 391
Query: 386 SCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRC-NGSGFCECKTGT 444
+C+HNT G +CE C GY+R +D + CI C C+P + D C GSG C CK
Sbjct: 392 NCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHA--DGCEQGSGRCHCKPNF 449
Query: 445 TGPKCDECLPGNSWHYGC--------------QPNVCDNELLHCQNGGT----CHNNVRC 486
G C++C G C P D + C G C + RC
Sbjct: 450 HGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRC 509
Query: 487 LCPAAYTGILCEKLR 501
LC G C+ R
Sbjct: 510 LCRPGVEGPRCDTCR 524
Score = 91.7 bits (226), Expect = 2e-18
Identities = 61/177 (34%), Positives = 75/177 (42%), Gaps = 41/177 (23%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCS 374
C C G C C SPG Y C+P C C GHSN+C
Sbjct: 1654 CACPPAYAGDSCQGC---------SPGYYRDHKGLYTGRCVP-------CNCNGHSNQCQ 1697
Query: 375 YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRC-- 432
+ ICV+C+HNT G+HCE C+ GY+ NA C C C S C
Sbjct: 1698 D----GSGICVNCQHNTAGEHCERCQEGYYGNAV-----HGSCRACPCPHTNSFATGCVV 1748
Query: 433 -NGSGFCECKTGTTGPKCDECLP---GNSWHYG--CQPNVCDNELLHCQNG--GTCH 481
G C CK G TG +C+ C P GN +G CQP C++ NG G+CH
Sbjct: 1749 NGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNS------NGQLGSCH 1799
Score = 70.5 bits (171), Expect = 4e-12
Identities = 58/203 (28%), Positives = 80/203 (39%), Gaps = 37/203 (18%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRP-----WSP--GSY-LPIPK 348
C CNL + ++ C C GP C C+ + P W GSY +P
Sbjct: 491 CDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSS 550
Query: 349 GTANT-CIPSISSIGNCE-----------CFGHSNRCSYIDLLNTVI-CVSCKHNTRGQH 395
T C P ++ C+ C G S+ C +N+ + CK + G
Sbjct: 551 VTGQCECRPGVTG-QRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPT 609
Query: 396 CELCRLGYFRNASAQLDDENV--CIECYCNPLGSIHD--RCN-GSGFCECKTGTTGPKCD 450
C C+L Y+ LD EN C EC C+ G++ C G G C CK+ G CD
Sbjct: 610 CSRCKLLYWN-----LDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCD 664
Query: 451 ECLPG-----NSWHYGCQPNVCD 468
C G S ++GCQ CD
Sbjct: 665 TCEDGYFALEKSNYFGCQGCQCD 687
Score = 63.9 bits (154), Expect = 3e-10
Identities = 49/159 (30%), Positives = 59/159 (37%), Gaps = 26/159 (16%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
C CN H+ C D S + C+HNT G C +C++ Y G GS P C
Sbjct: 1687 CNCNGHSNQC-QDGSGICVNCQHNTAGEHCERCQEGYYGNA-VHGSCRACP------CPH 1738
Query: 357 SISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENV 416
+ S C G RC SCK G CE C GYF N
Sbjct: 1739 TNSFATGCVVNGGDVRC------------SCKAGYTGTQCERCAPGYFGNPQ---KFGGS 1783
Query: 417 CIECYCN---PLGSIHDRCNGSGFCECKTGTTGPKCDEC 452
C C CN LGS H E K + +CD+C
Sbjct: 1784 CQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 59.7 bits (143), Expect = 7e-09
Identities = 38/121 (31%), Positives = 52/121 (42%), Gaps = 9/121 (7%)
Query: 383 ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFC-ECK 441
IC +C G C+ C GY+R+ C+ C CN G + +GSG C C+
Sbjct: 1653 IC-ACPPAYAGDSCQGCSPGYYRDHKGLYTGR--CVPCNCN--GHSNQCQDGSGICVNCQ 1707
Query: 442 TGTTGPKCDECLPG---NSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCE 498
T G C+ C G N+ H C+ C + +VRC C A YTG CE
Sbjct: 1708 HNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 1767
Query: 499 K 499
+
Sbjct: 1768 R 1768
Score = 53.5 bits (127), Expect = 5e-07
Identities = 48/195 (24%), Positives = 69/195 (35%), Gaps = 46/195 (23%)
Query: 297 CKCNL-HATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPI-PKGTANTC 354
C C+ HA C + + C C+ N G +C KC Y P+ +PI P T ++
Sbjct: 426 CSCDPEHADGCEQGSGR--CHCKPNFHGDNCEKCAIGYYNFPFC--LRIPIFPVSTPSSE 481
Query: 355 IPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRN-------- 406
P I C+C D +C + G C+ CR G++
Sbjct: 482 DPVAGDIKGCDCNLEGVLPEICDAHGRCLC---RPGVEGPRCDTCRSGFYSFPICQACWC 538
Query: 407 ---ASAQLDDENVCIECYCNP----------LGSIHD--RCNGS--------------GF 437
S Q+ +V +C C P L +D C GS G+
Sbjct: 539 SALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGY 598
Query: 438 CECKTGTTGPKCDEC 452
C+CK GP C C
Sbjct: 599 CQCKLHVEGPTCSRC 613
Score = 51.2 bits (121), Expect = 2e-06
Identities = 55/196 (28%), Positives = 69/196 (35%), Gaps = 49/196 (25%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHN-TTGPDCGK------CKKNYQGRPWS---PGSYLPI 346
CK + + V Y L CEC TGP C C+ N GR + G Y
Sbjct: 1248 CKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHY-GF 1306
Query: 347 PKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRN 406
P+ C P S G C + +C C T CE+C F
Sbjct: 1307 PR-----CKPC--SCGRRLCEEMTGQCR------------CPPRTVRPQCEVCETHSF-- 1345
Query: 407 ASAQLDDENVCIECYCNPLGSIH---DRCN-GSGFCECKTGTTGPKCD----------EC 452
C C C+ G+I C+ SG C CK TG +CD EC
Sbjct: 1346 ---SFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPEC 1402
Query: 453 LPGNSWHYGCQPNVCD 468
+P N G +P VCD
Sbjct: 1403 VPCNCNRDGTEPGVCD 1418
Score = 50.1 bits (118), Expect = 5e-06
Identities = 41/165 (24%), Positives = 62/165 (37%), Gaps = 34/165 (20%)
Query: 296 RCK-CNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKN-YQGRPWSPGSYLPIPK-GTAN 352
RCK C+ +C + C C T P C C+ + + P + + GT
Sbjct: 1308 RCKPCSCGRRLC--EEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIE 1365
Query: 353 TCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLD 412
+P EC S +C CK G+ C+ C G++R
Sbjct: 1366 AAMP--------ECDRDSGQCR------------CKPRITGRQCDRCASGFYRFPE---- 1401
Query: 413 DENVCIECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPGN 456
C+ C CN G+ C+ G+G C CK G +C+ C G+
Sbjct: 1402 ----CVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGS 1442
Score = 42.7 bits (99), Expect = 8e-04
Identities = 34/118 (28%), Positives = 43/118 (36%), Gaps = 25/118 (21%)
Query: 418 IECYCNPLGSIHDRCNGSGF-CECKTGTTGPKCDECLPGNSWHYG---CQPNVCDNELLH 473
+ C C+P G+ C+ G C C+ G +C C G HYG C+P C L
Sbjct: 1264 LPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATG---HYGFPRCKPCSCGRRLCE 1320
Query: 474 CQNGGTCH---NNVRCLCPAAYTGIL-------CEKLRCEEAGS-------CGSDSGQ 514
+ G C VR C T CE C G+ C DSGQ
Sbjct: 1321 -EMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQ 1377
Score = 42.7 bits (99), Expect = 8e-04
Identities = 35/145 (24%), Positives = 51/145 (35%), Gaps = 38/145 (26%)
Query: 297 CKCNLHATV------CVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGT 350
C C+ T+ C D+ + C C+ TG C +C + P
Sbjct: 1356 CNCSRRGTIEAAMPECDRDSGQ--CRCKPRITGRQCDRCASGFYRFP------------- 1400
Query: 351 ANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQ 410
C+P C C D T C+ CK N G C +CR G F A
Sbjct: 1401 --ECVP-------CNCNRDGTEPGVCDP-GTGACL-CKENVEGTECNVCREGSFHLDPAN 1449
Query: 411 LDDENVCIECYCNPLGSIHDRCNGS 435
L C C+C ++++C+ S
Sbjct: 1450 LKG---CTSCFC---FGVNNQCHSS 1468
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 176 bits (446), Expect = 5e-44
Identities = 138/495 (27%), Positives = 204/495 (41%), Gaps = 99/495 (20%)
Query: 71 TCGD--------PPETFC-------AMGNPYMCNNE----CDASTPELAHPPELMFDFEG 111
TCG+ PE +C A G+ + + C++ P AHP D
Sbjct: 65 TCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSE 124
Query: 112 RHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRT 171
R +WQS + +VN+TL + + ++ S RPD +LE+S+D+G T
Sbjct: 125 R----WWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGST 180
Query: 172 WQPYQYYA---TDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTT-NSKIIHFEIKD 227
+ P+QY+A DCL F + +++C EYS N +++ I
Sbjct: 181 YSPWQYFAHSKVDCLKEFGREANMAVTRDD----DVLCVTEYSRIVPLENGEVVVSLING 236
Query: 228 RFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRP------AVGEIFVDELHL 281
R P +N + LR+F T++R+R LR + + D
Sbjct: 237 R------PGAKNFTFSH-------TLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVT 283
Query: 282 ARYFYAISDIKVRGRCKCNLHATVCVYDNSK--LTCECEHNTTGPDCGKCKKNYQGRPWS 339
RY+Y+I DI + G+C CN HA VC +N + CEC+H+T G C +C Y R W
Sbjct: 284 RRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWR 343
Query: 340 PGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYID-------LLNTV-------ICV 385
P ++ + A C C GH++ C Y LNT +C+
Sbjct: 344 PAAWEQSHECEA------------CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCI 391
Query: 386 SCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRC-NGSGFCECKTGT 444
+C+HNT G +CE C GY+R +D + CI C C+P + D C GSG C CK
Sbjct: 392 NCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHA--DGCEQGSGRCHCKPNF 449
Query: 445 TGPKCDECLPGNSWHYGC--------------QPNVCDNELLHCQNGGT----CHNNVRC 486
G C++C G C P D + C G C + RC
Sbjct: 450 HGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRC 509
Query: 487 LCPAAYTGILCEKLR 501
LC G C+ R
Sbjct: 510 LCRPGVEGPRCDTCR 524
Score = 91.7 bits (226), Expect = 2e-18
Identities = 61/177 (34%), Positives = 75/177 (42%), Gaps = 41/177 (23%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCS 374
C C G C C SPG Y C+P C C GHSN+C
Sbjct: 1654 CACPPAYAGDSCQGC---------SPGYYRDHKGLYTGRCVP-------CNCNGHSNQCQ 1697
Query: 375 YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRC-- 432
+ ICV+C+HNT G+HCE C+ GY+ NA C C C S C
Sbjct: 1698 D----GSGICVNCQHNTAGEHCERCQEGYYGNAV-----HGSCRACPCPHTNSFATGCVV 1748
Query: 433 -NGSGFCECKTGTTGPKCDECLP---GNSWHYG--CQPNVCDNELLHCQNG--GTCH 481
G C CK G TG +C+ C P GN +G CQP C++ NG G+CH
Sbjct: 1749 NGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNS------NGQLGSCH 1799
Score = 70.5 bits (171), Expect = 4e-12
Identities = 58/203 (28%), Positives = 80/203 (39%), Gaps = 37/203 (18%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRP-----WSP--GSY-LPIPK 348
C CNL + ++ C C GP C C+ + P W GSY +P
Sbjct: 491 CDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSS 550
Query: 349 GTANT-CIPSISSIGNCE-----------CFGHSNRCSYIDLLNTVI-CVSCKHNTRGQH 395
T C P ++ C+ C G S+ C +N+ + CK + G
Sbjct: 551 VTGQCECRPGVTG-QRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPT 609
Query: 396 CELCRLGYFRNASAQLDDENV--CIECYCNPLGSIHD--RCN-GSGFCECKTGTTGPKCD 450
C C+L Y+ LD EN C EC C+ G++ C G G C CK+ G CD
Sbjct: 610 CSRCKLLYWN-----LDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCD 664
Query: 451 ECLPG-----NSWHYGCQPNVCD 468
C G S ++GCQ CD
Sbjct: 665 TCEDGYFALEKSNYFGCQGCQCD 687
Score = 63.9 bits (154), Expect = 3e-10
Identities = 49/159 (30%), Positives = 59/159 (37%), Gaps = 26/159 (16%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
C CN H+ C D S + C+HNT G C +C++ Y G GS P C
Sbjct: 1687 CNCNGHSNQC-QDGSGICVNCQHNTAGEHCERCQEGYYGNA-VHGSCRACP------CPH 1738
Query: 357 SISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENV 416
+ S C G RC SCK G CE C GYF N
Sbjct: 1739 TNSFATGCVVNGGDVRC------------SCKAGYTGTQCERCAPGYFGNPQ---KFGGS 1783
Query: 417 CIECYCN---PLGSIHDRCNGSGFCECKTGTTGPKCDEC 452
C C CN LGS H E K + +CD+C
Sbjct: 1784 CQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 59.7 bits (143), Expect = 7e-09
Identities = 38/121 (31%), Positives = 52/121 (42%), Gaps = 9/121 (7%)
Query: 383 ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFC-ECK 441
IC +C G C+ C GY+R+ C+ C CN G + +GSG C C+
Sbjct: 1653 IC-ACPPAYAGDSCQGCSPGYYRDHKGLYTGR--CVPCNCN--GHSNQCQDGSGICVNCQ 1707
Query: 442 TGTTGPKCDECLPG---NSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCE 498
T G C+ C G N+ H C+ C + +VRC C A YTG CE
Sbjct: 1708 HNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 1767
Query: 499 K 499
+
Sbjct: 1768 R 1768
Score = 53.5 bits (127), Expect = 5e-07
Identities = 48/195 (24%), Positives = 69/195 (35%), Gaps = 46/195 (23%)
Query: 297 CKCNL-HATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPI-PKGTANTC 354
C C+ HA C + + C C+ N G +C KC Y P+ +PI P T ++
Sbjct: 426 CSCDPEHADGCEQGSGR--CHCKPNFHGDNCEKCAIGYYNFPFC--LRIPIFPVSTPSSE 481
Query: 355 IPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRN-------- 406
P I C+C D +C + G C+ CR G++
Sbjct: 482 DPVAGDIKGCDCNLEGVLPEICDAHGRCLC---RPGVEGPRCDTCRSGFYSFPICQACWC 538
Query: 407 ---ASAQLDDENVCIECYCNP----------LGSIHD--RCNGS--------------GF 437
S Q+ +V +C C P L +D C GS G+
Sbjct: 539 SALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGY 598
Query: 438 CECKTGTTGPKCDEC 452
C+CK GP C C
Sbjct: 599 CQCKLHVEGPTCSRC 613
Score = 51.2 bits (121), Expect = 2e-06
Identities = 55/196 (28%), Positives = 69/196 (35%), Gaps = 49/196 (25%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHN-TTGPDCGK------CKKNYQGRPWS---PGSYLPI 346
CK + + V Y L CEC TGP C C+ N GR + G Y
Sbjct: 1248 CKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHY-GF 1306
Query: 347 PKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRN 406
P+ C P S G C + +C C T CE+C F
Sbjct: 1307 PR-----CKPC--SCGRRLCEEMTGQCR------------CPPRTVRPQCEVCETHSF-- 1345
Query: 407 ASAQLDDENVCIECYCNPLGSIH---DRCN-GSGFCECKTGTTGPKCD----------EC 452
C C C+ G+I C+ SG C CK TG +CD EC
Sbjct: 1346 ---SFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPEC 1402
Query: 453 LPGNSWHYGCQPNVCD 468
+P N G +P VCD
Sbjct: 1403 VPCNCNRDGTEPGVCD 1418
Score = 50.1 bits (118), Expect = 5e-06
Identities = 41/165 (24%), Positives = 62/165 (37%), Gaps = 34/165 (20%)
Query: 296 RCK-CNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKN-YQGRPWSPGSYLPIPK-GTAN 352
RCK C+ +C + C C T P C C+ + + P + + GT
Sbjct: 1308 RCKPCSCGRRLC--EEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIE 1365
Query: 353 TCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLD 412
+P EC S +C CK G+ C+ C G++R
Sbjct: 1366 AAMP--------ECDRDSGQCR------------CKPRITGRQCDRCASGFYRFPE---- 1401
Query: 413 DENVCIECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPGN 456
C+ C CN G+ C+ G+G C CK G +C+ C G+
Sbjct: 1402 ----CVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGS 1442
Score = 42.7 bits (99), Expect = 8e-04
Identities = 34/118 (28%), Positives = 43/118 (36%), Gaps = 25/118 (21%)
Query: 418 IECYCNPLGSIHDRCNGSGF-CECKTGTTGPKCDECLPGNSWHYG---CQPNVCDNELLH 473
+ C C+P G+ C+ G C C+ G +C C G HYG C+P C L
Sbjct: 1264 LPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATG---HYGFPRCKPCSCGRRLCE 1320
Query: 474 CQNGGTCH---NNVRCLCPAAYTGIL-------CEKLRCEEAGS-------CGSDSGQ 514
+ G C VR C T CE C G+ C DSGQ
Sbjct: 1321 -EMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQ 1377
Score = 42.7 bits (99), Expect = 8e-04
Identities = 35/145 (24%), Positives = 51/145 (35%), Gaps = 38/145 (26%)
Query: 297 CKCNLHATV------CVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGT 350
C C+ T+ C D+ + C C+ TG C +C + P
Sbjct: 1356 CNCSRRGTIEAAMPECDRDSGQ--CRCKPRITGRQCDRCASGFYRFP------------- 1400
Query: 351 ANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQ 410
C+P C C D T C+ CK N G C +CR G F A
Sbjct: 1401 --ECVP-------CNCNRDGTEPGVCDP-GTGACL-CKENVEGTECNVCREGSFHLDPAN 1449
Query: 411 LDDENVCIECYCNPLGSIHDRCNGS 435
L C C+C ++++C+ S
Sbjct: 1450 LKG---CTSCFC---FGVNNQCHSS 1468
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 171 bits (433), Expect = 2e-42
Identities = 136/454 (29%), Positives = 197/454 (43%), Gaps = 92/454 (20%)
Query: 71 TCGDP-PETFCAM-----GNPYMCNNECDASTPELAHPPELMFDFEGRHP--------ST 116
TCG+ PE FC + G P N +C A+P E RHP +
Sbjct: 40 TCGEKGPEMFCKLVEHVPGRPVR-NPQCRICDGNSANPRE-------RHPISHAIDGTNN 91
Query: 117 FWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQ 176
+WQS + + + V ITL + ++ I+ + RP ILE+SLD G T+ P+Q
Sbjct: 92 WWQSPSIQNGREYHWVTITLDLRQVFQVAYVIIKAANAPRPGNWILERSLD-GTTFSPWQ 150
Query: 177 YYA---TDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFA 233
YYA ++CL +++ P+ + E+ICT YS IH + +
Sbjct: 151 YYAVSDSECLSRYNITPRRGPP-TYRADDEVICTSYYSRLVPLEHGEIHTSLING----- 204
Query: 234 GPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRL--LRPAVGEIF---------VDELHLA 282
R A D + KL +F + +R+RL +R ++ +D +
Sbjct: 205 ----RPSAD-----DLSPKLLEFTSARYIRLRLQRIRTLNADLMTLSHREPKELDPIVTR 255
Query: 283 RYFYAISDIKVRGRCKCNLHATVCVYDNS--KLTCECEHNTTGPDCGKCKKNYQGRPWSP 340
RY+Y+I DI V G C C HA+ C +D + KL C+CEHNT G C +C Y +PW P
Sbjct: 256 RYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRP 315
Query: 341 GSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDL-------LNTV-------ICVS 386
G+ + NTC C C + C Y + LNT +C++
Sbjct: 316 GTV-----SSGNTCEA-------CNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCIN 363
Query: 387 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRC----------NGS- 435
C NT G +CE C GY+R ++ C C C+P+GS+ C NG
Sbjct: 364 CLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQ 423
Query: 436 -GFCECKTGTTGPKCDECLPGNSWHYGCQPNVCD 468
G C CK G TG KCD C G + C C+
Sbjct: 424 PGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCN 457
Score = 87.8 bits (216), Expect = 2e-17
Identities = 75/255 (29%), Positives = 98/255 (38%), Gaps = 54/255 (21%)
Query: 300 NLHATVCVYDNSKLTCE-CEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSI 358
N T + D ++ C+ C +G C +C Y G P PG +P + PS
Sbjct: 801 NFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESC-VPCDCSGNVDPSE 859
Query: 359 -----SSIGNC-ECFG-----HSNRC-------------------------SYIDLLNTV 382
S G C +C G H RC S + L T
Sbjct: 860 AGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETG 919
Query: 383 ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKT 442
+C CK N GQ C+ C GY+ LD + C C C+ GS+ D C G C C
Sbjct: 920 LC-DCKPNVTGQQCDQCLHGYYG-----LDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVP 973
Query: 443 GTTGPKCDECLPGNSWHYGCQPNVCDN-ELLHCQNGGTCHNNV-RCLCPAAYTGILCEKL 500
G G +CD C G Y Q C + H QN TC C+CP G+ CE+
Sbjct: 974 GVAGKRCDRCAHG---FYAYQDGSCTPCDCPHTQN--TCDPETGECVCPPHTQGVKCEE- 1027
Query: 501 RCEEAGSCGSDSGQG 515
CE+ G G D+ G
Sbjct: 1028 -CED-GHWGYDAEVG 1040
Score = 81.3 bits (199), Expect = 2e-15
Identities = 70/253 (27%), Positives = 102/253 (40%), Gaps = 62/253 (24%)
Query: 297 CKCNLHATVCVYDNSKLTC-ECEHNTTGPDCGKCKKNYQGRP--WSPGSYLPI------- 346
C+C+ HA C N C C HNTTG C +C + G P +PG P
Sbjct: 742 CECHGHAAEC---NVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIA 798
Query: 347 -------------PKGTANTCIPSISS----------IGN----------CECFGH--SN 371
+ + C P S GN C+C G+ +
Sbjct: 799 SNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPS 858
Query: 372 RCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDR 431
+ D + T C+ C NT G HCE C G++ +A + C C C+ GS
Sbjct: 859 EAGHCDSV-TGECLKCLGNTDGAHCERCADGFYGDAVTAKN----CRACECHVKGSHSAV 913
Query: 432 CN-GSGFCECKTGTTGPKCDECLPG----NSWHYGCQPNVCDNELLHCQNGGTCHNNVRC 486
C+ +G C+CK TG +CD+CL G +S H GC+P C+ + + G C + +C
Sbjct: 914 CHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGH-GCRP--CNCSVAGSVSDG-CTDEGQC 969
Query: 487 LCPAAYTGILCEK 499
C G C++
Sbjct: 970 HCVPGVAGKRCDR 982
Score = 79.0 bits (193), Expect = 1e-14
Identities = 51/164 (31%), Positives = 69/164 (42%), Gaps = 28/164 (17%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
C CN H+ C + K C NT G C C Y G+ G+A+ C
Sbjct: 1403 CSCNNHSDTCDPNTGKCL-NCGDNTAGDHCDVCTSGYYGKV----------TGSASDC-- 1449
Query: 357 SISSIGNCECFGHSNRCSY-----IDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQL 411
C C HS S+ ++ + C +C G+HCE C Y+ N
Sbjct: 1450 -----ALCAC-PHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTP- 1502
Query: 412 DDENVCIECYCNPLGSIHDRCNG-SGFCECKTGTTGPKCDECLP 454
C +C CNP GS+H C+ SG C C+ G +G +CDEC P
Sbjct: 1503 --GGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEP 1544
Score = 74.3 bits (181), Expect = 3e-13
Identities = 68/261 (26%), Positives = 101/261 (38%), Gaps = 52/261 (19%)
Query: 297 CKCNL---HATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQG-------RPWSPGSYLPI 346
C+C++ H+ VC + C+C+ N TG C +C Y G RP + +
Sbjct: 902 CECHVKGSHSAVCHLETG--LCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSV 959
Query: 347 PKGTANT----CIPSIS-----------------SIGNCECFGHSNRCSYIDLLNTVICV 385
G + C+P ++ S C+C N C T CV
Sbjct: 960 SDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDP----ETGECV 1015
Query: 386 SCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNG-SGFCECKTGT 444
C +T+G CE C G++ D E C C C+ +GS H RC+ +G C+CK+
Sbjct: 1016 -CPPHTQGVKCEECEDGHWG-----YDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKF 1069
Query: 445 TGPKCDECLPGNSWHYGCQPNVCD-----NELLHCQNG--GTCHNNVRCLCPAAYTGILC 497
G CD+C G C P CD + + + G G C C G C
Sbjct: 1070 GGRACDQCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQC 1129
Query: 498 EKLRCEEAGSCGSDSGQGAPP 518
+ R E + +D+ G P
Sbjct: 1130 NECR-EGTFALRADNPLGCSP 1149
Score = 71.2 bits (173), Expect = 2e-12
Identities = 73/264 (27%), Positives = 104/264 (39%), Gaps = 44/264 (16%)
Query: 255 DFFTV-TDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVR-GRCKCNLHATVCVYDNSK 312
DF +V +D+ L++ + G+ L +R ISDI + GR LH V +
Sbjct: 1309 DFMSVLSDIEYILIKASYGQ----GLQQSR----ISDISMEVGRKAEKLHPEEEVASLLE 1360
Query: 313 LTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNR 372
C C T G C C Y GS P+ C+P C C HS+
Sbjct: 1361 -NCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRG-PRPLVAPCVP-------CSCNNHSDT 1411
Query: 373 CSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRC 432
C NT C++C NT G HC++C GY+ + D +C C +P S C
Sbjct: 1412 CDP----NTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALC-ACPHSPPASFSPTC 1466
Query: 433 NGSG----FCE-CKTGTTGPKCDECLP---GNSWHYGCQPNVCDNELLHCQNGGTCHNNV 484
G C+ C G G C+ C GN G CD C G+ H +
Sbjct: 1467 VLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCD-----CNPHGSVHGDC 1521
Query: 485 -----RCLCPAAYTGILCEKLRCE 503
+C+C +G+ C++ CE
Sbjct: 1522 DRTSGQCVCRLGASGLRCDE--CE 1543
Score = 62.0 bits (149), Expect = 1e-09
Identities = 53/195 (27%), Positives = 70/195 (35%), Gaps = 51/195 (26%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCS 374
CEC TG C C Y Y C P CEC GH+ C+
Sbjct: 709 CECPQGYTGTSCESCLSGY---------YRVDGILFGGICQP-------CECHGHAAECN 752
Query: 375 YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYC-------NPLGS 427
+C++C HNT G HCE C G++ S + C C C N +
Sbjct: 753 VHG-----VCIACAHNTTGVHCEQCLPGFYGEPSRGTPGD--CQPCACPLTIASNNFSPT 805
Query: 428 IHDRCNGSGFCE-CKTGTTGPKCDECLPGNSWHYG-------------CQPNVCDNELLH 473
H C+ C G +G C+ C G +YG C NV +E H
Sbjct: 806 CHLNDGDEVVCDWCAPGYSGAWCERCADG---YYGNPTVPGESCVPCDCSGNVDPSEAGH 862
Query: 474 CQN-GGTCHNNVRCL 487
C + G C ++CL
Sbjct: 863 CDSVTGEC---LKCL 874
Score = 38.9 bits (89), Expect = 0.012
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 33/110 (30%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCS 374
C C+ TG C +C+ Y+ P TC+ C G ++
Sbjct: 427 CPCKEGYTGEKCDRCQLGYKDYP---------------TCVSC-----GCNPVGSAS--- 463
Query: 375 YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENV--CIECYC 422
D T CV CK N G+ C+ C+ G++ L ++N C EC+C
Sbjct: 464 --DEPCTGPCV-CKENVEGKACDRCKPGFY-----NLKEKNPRGCSECFC 505
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 169 bits (429), Expect = 5e-42
Identities = 134/482 (27%), Positives = 207/482 (42%), Gaps = 88/482 (18%)
Query: 71 TCGDP-PETFCAM-----GNPYMCNNEC-----DASTPELAHPPELMFDFEGRHPSTFWQ 119
TCG+ PE +C + G P N +C ++S P HP D + +T+WQ
Sbjct: 57 TCGEKGPEMYCKLVEHVPGQPVR-NPQCRICNQNSSNPNQRHPITNAIDGK----NTWWQ 111
Query: 120 SATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYA 179
S + K + V ITL + ++ IV S RP ILE+SLD ++P+QY+A
Sbjct: 112 SPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLD-DVEYKPWQYHA 170
Query: 180 ---TDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPR 236
T+CL +++ P++ S E+ICT YS + + IH + +
Sbjct: 171 VTDTECLTLYNIYPRTGPP-SYAKDDEVICTSFYSKIHPLENGEIHISLING-------- 221
Query: 237 LRNMASLYGQLDTTKKLRDFFTVTDLRIRL--LRPAVGEIF---------VDELHLARYF 285
R A D + +L +F + +R+R +R ++ +D + RY+
Sbjct: 222 -RPSAD-----DPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYY 275
Query: 286 YAISDIKVRGRCKCNLHATVCVYD--NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSY 343
Y++ DI V G C C HA C D +K CECEHNT G C +C + +PW G++
Sbjct: 276 YSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTF 335
Query: 344 LPIPKGTANTCIPSISSIGNCECFGHSNRCSYID--------------LLNTVICVSCKH 389
L T C C C G + C Y + + +C++C
Sbjct: 336 L-----TKTECEA-------CNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQ 383
Query: 390 NTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRC----------NGSGFCE 439
NT G +CE C G+FR + C C+C+P+GS+++ C G C
Sbjct: 384 NTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCH 443
Query: 440 CKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEK 499
CKTG G CD C G + + C+ C+ L +N C C+C G C +
Sbjct: 444 CKTGFGGVSCDRCARGYTGYPDCK--ACNCSGLGSKNEDPCFG--PCICKENVEGGDCSR 499
Query: 500 LR 501
+
Sbjct: 500 CK 501
Score = 87.8 bits (216), Expect = 2e-17
Identities = 65/215 (30%), Positives = 92/215 (42%), Gaps = 35/215 (16%)
Query: 297 CKCNLH------ATVCVYDNSK-LTCE-CEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPK 348
C C L+ + C D S L C+ C TGP C +C + Y G+P PG +
Sbjct: 807 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ 866
Query: 349 GTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNAS 408
N S G+C+ S C+ CK T G++CELC GYF +A
Sbjct: 867 CNDNL---DFSIPGSCDSLSGS-------------CLICKPGTTGRYCELCADGYFGDA- 909
Query: 409 AQLDDENVCIECYCNPLGSIHDRCNG-SGFCECKTGTTGPKCDECLPGN---SWHYGCQP 464
+D +N C C CN GS + C+ +G CEC+ G +CD+C G GC P
Sbjct: 910 --VDAKN-CQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVP 966
Query: 465 NVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEK 499
C++ C + +C C TG C++
Sbjct: 967 CNCNS---FGSKSFDCEESGQCWCQPGVTGKKCDR 998
Score = 87.8 bits (216), Expect = 2e-17
Identities = 57/168 (33%), Positives = 77/168 (45%), Gaps = 28/168 (16%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTC-- 354
C+CN H+++C + S + C+H+T G C +C Y G I KG N C
Sbjct: 1420 CQCNGHSSLCDPETS-ICQNCQHHTAGDFCERCALGYYG----------IVKGLPNDCQQ 1468
Query: 355 --IPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLD 412
P ISS N S C + L+ C +C GQ+CE C GY + +
Sbjct: 1469 CACPLISSSNN-----FSPSC-VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPG---N 1519
Query: 413 DENVCIECYCNPLGSIHDRCNG-SGFCECKTGTTGPKCDECLPGNSWH 459
C EC C+P GS+ C+ +GFC C+ G TG KCD C WH
Sbjct: 1520 PGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC---KHWH 1564
Score = 76.6 bits (187), Expect = 5e-14
Identities = 51/167 (30%), Positives = 69/167 (41%), Gaps = 29/167 (17%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCS 374
C+C +G C C + PG P P T TC+P C+C GHS+ C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGP--TLGTCVP-------CQCNGHSSLCD 1430
Query: 375 YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHD---R 431
T IC +C+H+T G CE C LGY+ +D C +C C + S ++
Sbjct: 1431 P----ETSICQNCQHHTAGDFCERCALGYYGIVKGLPND---CQQCACPLISSSNNFSPS 1483
Query: 432 CNGSGFCE-----CKTGTTGPKCDECLPGNSWHYG-----CQPNVCD 468
C G + C G G C+ C PG + G CQ CD
Sbjct: 1484 CVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECD 1530
Score = 68.9 bits (167), Expect = 1e-11
Identities = 62/225 (27%), Positives = 85/225 (37%), Gaps = 38/225 (16%)
Query: 278 ELHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKL-TCECEHNTTGPDCGKCKKNYQGR 336
EL YF D K C+CN + +S+ CEC N G C KCK G
Sbjct: 899 ELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGL 958
Query: 337 PWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHC 396
+A C+P NC FG + D + C C+ G+ C
Sbjct: 959 Q------------SARGCVPC-----NCNSFGSKS----FDCEESGQCW-CQPGVTGKKC 996
Query: 397 ELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGN 456
+ C GYF E C C C+ LG+ D G C C T G KC +C P N
Sbjct: 997 DRCAHGYFNF------QEGGCTACECSHLGNNCDPKTGR--CICPPNTIGEKCSKCAP-N 1047
Query: 457 SWHY----GCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILC 497
+W + GC+ C+ + + N +C C ++G C
Sbjct: 1048 TWGHSITTGCK--ACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKC 1090
Score = 65.9 bits (159), Expect = 9e-11
Identities = 65/243 (26%), Positives = 90/243 (37%), Gaps = 73/243 (30%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGT--ANTCIPSISSIGNCECFGHSNR 372
C+C TG C C ++ GT C P C+CFGH+
Sbjct: 724 CQCPPGYTGSSCESCWPRHRR-----------VNGTIFGGICEP-------CQCFGHAES 765
Query: 373 CSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYC-------NPL 425
C + T C++CK +T G +C+ C G++ + ++ C C C N
Sbjct: 766 CDDV----TGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSED--CQPCACPLNIPSNNFS 819
Query: 426 GSIH-DRCNGSGFCECKTGTTGPKCDEC---------LPGNSWHYGCQPNVCDNEL---- 471
+ H DR G C G TGP+C+ C +PG S CQP C++ L
Sbjct: 820 PTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGS----CQPCQCNDNLDFSI 875
Query: 472 -----------LHCQNGGTCHNNVRCLCPAAYTGIL-----CEKLRCEEAGS----CGSD 511
L C+ G T LC Y G C+ RC GS C S
Sbjct: 876 PGSCDSLSGSCLICKPGTT--GRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQ 933
Query: 512 SGQ 514
+GQ
Sbjct: 934 TGQ 936
Score = 50.4 bits (119), Expect = 4e-06
Identities = 49/151 (32%), Positives = 57/151 (37%), Gaps = 31/151 (20%)
Query: 387 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFC-ECKTGTT 445
C G CE C + R +C C C G + +G C CK T
Sbjct: 726 CPPGYTGSSCESCWPRHRRVNGTIFG--GICEPCQC--FGHAESCDDVTGECLNCKDHTG 781
Query: 446 GPKCDECLPGNSWHYG---------CQPNVCDNELLHCQNGGTCHNNVRCL------CPA 490
GP CD+CLPG YG CQP C + TCH + R L CP
Sbjct: 782 GPYCDKCLPG---FYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLD-RSLGLICDGCPV 837
Query: 491 AYTGILCEKLRCEEAGSCGSDSGQGAPPHGS 521
YTG CE RC E GQ + P GS
Sbjct: 838 GYTGPRCE--RCAE-----GYFGQPSVPGGS 861
Score = 45.8 bits (107), Expect = 1e-04
Identities = 38/160 (23%), Positives = 54/160 (33%), Gaps = 23/160 (14%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
C+C+ C D C C NT G C KC N G + G C
Sbjct: 1014 CECSHLGNNC--DPKTGRCICPPNTIGEKCSKCAPNTWGHSITTG---------CKACNC 1062
Query: 357 SISSIGNCECFGHSNRCSYIDLLNTVICVSCKH-NTRGQHCELCRLGYFRNASAQLDDEN 415
S + +C ++ +C+ + C C + C LC + D E
Sbjct: 1063 STVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSET 1122
Query: 416 VCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPG 455
+C C+ + +G C CK G CD C PG
Sbjct: 1123 K--KCSCS---------DQTGQCTCKVNVEGIHCDRCRPG 1151
Score = 45.4 bits (106), Expect = 1e-04
Identities = 31/110 (28%), Positives = 41/110 (37%), Gaps = 22/110 (20%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCS 374
C C +G C +C + + P +P A TC S C C + +C+
Sbjct: 1079 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCD---SETKKCSCSDQTGQCT 1135
Query: 375 YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENV--CIECYC 422
CK N G HC+ CR G F LD +N C CYC
Sbjct: 1136 ------------CKVNVEGIHCDRCRPGKF-----GLDAKNPLGCSSCYC 1168
Score = 44.7 bits (104), Expect = 2e-04
Identities = 36/138 (26%), Positives = 50/138 (36%), Gaps = 39/138 (28%)
Query: 305 VCVYDNSKL-------TCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPS 357
VCV D +C C+ G C +C + Y G P A C
Sbjct: 425 VCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTG----------YPDCKACNC-SG 473
Query: 358 ISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVC 417
+ S CFG C+ CK N G C C+ G+F + Q D+ C
Sbjct: 474 LGSKNEDPCFGP--------------CI-CKENVEGGDCSRCKSGFF---NLQEDNWKGC 515
Query: 418 IECYCNPLGSIHDRCNGS 435
EC+C+ + +RC S
Sbjct: 516 DECFCS---GVSNRCQSS 530
Score = 42.4 bits (98), Expect = 0.001
Identities = 44/160 (27%), Positives = 59/160 (36%), Gaps = 32/160 (20%)
Query: 387 CKHNTRGQHCELCRLGYFRNASAQLDDE-----NVCIECYCNPLGSIHDRCNGSGFCE-C 440
C G CE C G++R S C+ C CN S+ D + C+ C
Sbjct: 1382 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDP--ETSICQNC 1439
Query: 441 KTGTTGPKCDECLPGNSWHYG--------CQPNVC------DNELLHCQNGGTCHNNVRC 486
+ T G C+ C G +YG CQ C +N C G ++ RC
Sbjct: 1440 QHHTAGDFCERCALG---YYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGL--DDYRC 1494
Query: 487 L-CPAAYTGILCEKLRCEEAGSCGSDSGQ----GAPPHGS 521
CP Y G CE+ GS G+ G P+GS
Sbjct: 1495 TACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGS 1534
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 169 bits (429), Expect = 5e-42
Identities = 134/482 (27%), Positives = 207/482 (42%), Gaps = 88/482 (18%)
Query: 71 TCGDP-PETFCAM-----GNPYMCNNEC-----DASTPELAHPPELMFDFEGRHPSTFWQ 119
TCG+ PE +C + G P N +C ++S P HP D + +T+WQ
Sbjct: 57 TCGEKGPEMYCKLVEHVPGQPVR-NPQCRICNQNSSNPNQRHPITNAIDGK----NTWWQ 111
Query: 120 SATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYA 179
S + K + V ITL + ++ IV S RP ILE+SLD ++P+QY+A
Sbjct: 112 SPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLD-DVEYKPWQYHA 170
Query: 180 ---TDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPR 236
T+CL +++ P++ S E+ICT YS + + IH + +
Sbjct: 171 VTDTECLTLYNIYPRTGPP-SYAKDDEVICTSFYSKIHPLENGEIHISLING-------- 221
Query: 237 LRNMASLYGQLDTTKKLRDFFTVTDLRIRL--LRPAVGEIF---------VDELHLARYF 285
R A D + +L +F + +R+R +R ++ +D + RY+
Sbjct: 222 -RPSAD-----DPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYY 275
Query: 286 YAISDIKVRGRCKCNLHATVCVYD--NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSY 343
Y++ DI V G C C HA C D +K CECEHNT G C +C + +PW G++
Sbjct: 276 YSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTF 335
Query: 344 LPIPKGTANTCIPSISSIGNCECFGHSNRCSYID--------------LLNTVICVSCKH 389
L T C C C G + C Y + + +C++C
Sbjct: 336 L-----TKTECEA-------CNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQ 383
Query: 390 NTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRC----------NGSGFCE 439
NT G +CE C G+FR + C C+C+P+GS+++ C G C
Sbjct: 384 NTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCH 443
Query: 440 CKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEK 499
CKTG G CD C G + + C+ C+ L +N C C+C G C +
Sbjct: 444 CKTGFGGVSCDRCARGYTGYPDCK--ACNCSGLGSKNEDPCFG--PCICKENVEGGDCSR 499
Query: 500 LR 501
+
Sbjct: 500 CK 501
Score = 87.8 bits (216), Expect = 2e-17
Identities = 65/215 (30%), Positives = 92/215 (42%), Gaps = 35/215 (16%)
Query: 297 CKCNLH------ATVCVYDNSK-LTCE-CEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPK 348
C C L+ + C D S L C+ C TGP C +C + Y G+P PG +
Sbjct: 807 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ 866
Query: 349 GTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNAS 408
N S G+C+ S C+ CK T G++CELC GYF +A
Sbjct: 867 CNDNL---DFSIPGSCDSLSGS-------------CLICKPGTTGRYCELCADGYFGDA- 909
Query: 409 AQLDDENVCIECYCNPLGSIHDRCNG-SGFCECKTGTTGPKCDECLPGN---SWHYGCQP 464
+D +N C C CN GS + C+ +G CEC+ G +CD+C G GC P
Sbjct: 910 --VDAKN-CQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVP 966
Query: 465 NVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEK 499
C++ C + +C C TG C++
Sbjct: 967 CNCNS---FGSKSFDCEESGQCWCQPGVTGKKCDR 998
Score = 87.8 bits (216), Expect = 2e-17
Identities = 57/168 (33%), Positives = 77/168 (45%), Gaps = 28/168 (16%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTC-- 354
C+CN H+++C + S + C+H+T G C +C Y G I KG N C
Sbjct: 1420 CQCNGHSSLCDPETS-ICQNCQHHTAGDFCERCALGYYG----------IVKGLPNDCQQ 1468
Query: 355 --IPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLD 412
P ISS N S C + L+ C +C GQ+CE C GY + +
Sbjct: 1469 CACPLISSSNN-----FSPSC-VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPG---N 1519
Query: 413 DENVCIECYCNPLGSIHDRCNG-SGFCECKTGTTGPKCDECLPGNSWH 459
C EC C+P GS+ C+ +GFC C+ G TG KCD C WH
Sbjct: 1520 PGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC---KHWH 1564
Score = 76.6 bits (187), Expect = 5e-14
Identities = 51/167 (30%), Positives = 69/167 (41%), Gaps = 29/167 (17%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCS 374
C+C +G C C + PG P P T TC+P C+C GHS+ C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGP--TLGTCVP-------CQCNGHSSLCD 1430
Query: 375 YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHD---R 431
T IC +C+H+T G CE C LGY+ +D C +C C + S ++
Sbjct: 1431 P----ETSICQNCQHHTAGDFCERCALGYYGIVKGLPND---CQQCACPLISSSNNFSPS 1483
Query: 432 CNGSGFCE-----CKTGTTGPKCDECLPGNSWHYG-----CQPNVCD 468
C G + C G G C+ C PG + G CQ CD
Sbjct: 1484 CVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECD 1530
Score = 68.9 bits (167), Expect = 1e-11
Identities = 62/225 (27%), Positives = 85/225 (37%), Gaps = 38/225 (16%)
Query: 278 ELHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKL-TCECEHNTTGPDCGKCKKNYQGR 336
EL YF D K C+CN + +S+ CEC N G C KCK G
Sbjct: 899 ELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGL 958
Query: 337 PWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHC 396
+A C+P NC FG + D + C C+ G+ C
Sbjct: 959 Q------------SARGCVPC-----NCNSFGSKS----FDCEESGQCW-CQPGVTGKKC 996
Query: 397 ELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGN 456
+ C GYF E C C C+ LG+ D G C C T G KC +C P N
Sbjct: 997 DRCAHGYFNF------QEGGCTACECSHLGNNCDPKTGR--CICPPNTIGEKCSKCAP-N 1047
Query: 457 SWHY----GCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILC 497
+W + GC+ C+ + + N +C C ++G C
Sbjct: 1048 TWGHSITTGCK--ACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKC 1090
Score = 65.9 bits (159), Expect = 9e-11
Identities = 65/243 (26%), Positives = 90/243 (37%), Gaps = 73/243 (30%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGT--ANTCIPSISSIGNCECFGHSNR 372
C+C TG C C ++ GT C P C+CFGH+
Sbjct: 724 CQCPPGYTGSSCESCWPRHRR-----------VNGTIFGGICEP-------CQCFGHAES 765
Query: 373 CSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYC-------NPL 425
C + T C++CK +T G +C+ C G++ + ++ C C C N
Sbjct: 766 CDDV----TGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSED--CQPCACPLNIPSNNFS 819
Query: 426 GSIH-DRCNGSGFCECKTGTTGPKCDEC---------LPGNSWHYGCQPNVCDNEL---- 471
+ H DR G C G TGP+C+ C +PG S CQP C++ L
Sbjct: 820 PTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGS----CQPCQCNDNLDFSI 875
Query: 472 -----------LHCQNGGTCHNNVRCLCPAAYTGIL-----CEKLRCEEAGS----CGSD 511
L C+ G T LC Y G C+ RC GS C S
Sbjct: 876 PGSCDSLSGSCLICKPGTT--GRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQ 933
Query: 512 SGQ 514
+GQ
Sbjct: 934 TGQ 936
Score = 50.4 bits (119), Expect = 4e-06
Identities = 49/151 (32%), Positives = 57/151 (37%), Gaps = 31/151 (20%)
Query: 387 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFC-ECKTGTT 445
C G CE C + R +C C C G + +G C CK T
Sbjct: 726 CPPGYTGSSCESCWPRHRRVNGTIFG--GICEPCQC--FGHAESCDDVTGECLNCKDHTG 781
Query: 446 GPKCDECLPGNSWHYG---------CQPNVCDNELLHCQNGGTCHNNVRCL------CPA 490
GP CD+CLPG YG CQP C + TCH + R L CP
Sbjct: 782 GPYCDKCLPG---FYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLD-RSLGLICDGCPV 837
Query: 491 AYTGILCEKLRCEEAGSCGSDSGQGAPPHGS 521
YTG CE RC E GQ + P GS
Sbjct: 838 GYTGPRCE--RCAE-----GYFGQPSVPGGS 861
Score = 45.8 bits (107), Expect = 1e-04
Identities = 38/160 (23%), Positives = 54/160 (33%), Gaps = 23/160 (14%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
C+C+ C D C C NT G C KC N G + G C
Sbjct: 1014 CECSHLGNNC--DPKTGRCICPPNTIGEKCSKCAPNTWGHSITTG---------CKACNC 1062
Query: 357 SISSIGNCECFGHSNRCSYIDLLNTVICVSCKH-NTRGQHCELCRLGYFRNASAQLDDEN 415
S + +C ++ +C+ + C C + C LC + D E
Sbjct: 1063 STVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSET 1122
Query: 416 VCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPG 455
+C C+ + +G C CK G CD C PG
Sbjct: 1123 K--KCSCS---------DQTGQCTCKVNVEGIHCDRCRPG 1151
Score = 45.4 bits (106), Expect = 1e-04
Identities = 31/110 (28%), Positives = 41/110 (37%), Gaps = 22/110 (20%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCS 374
C C +G C +C + + P +P A TC S C C + +C+
Sbjct: 1079 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCD---SETKKCSCSDQTGQCT 1135
Query: 375 YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENV--CIECYC 422
CK N G HC+ CR G F LD +N C CYC
Sbjct: 1136 ------------CKVNVEGIHCDRCRPGKF-----GLDAKNPLGCSSCYC 1168
Score = 44.7 bits (104), Expect = 2e-04
Identities = 36/138 (26%), Positives = 50/138 (36%), Gaps = 39/138 (28%)
Query: 305 VCVYDNSKL-------TCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPS 357
VCV D +C C+ G C +C + Y G P A C
Sbjct: 425 VCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTG----------YPDCKACNC-SG 473
Query: 358 ISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVC 417
+ S CFG C+ CK N G C C+ G+F + Q D+ C
Sbjct: 474 LGSKNEDPCFGP--------------CI-CKENVEGGDCSRCKSGFF---NLQEDNWKGC 515
Query: 418 IECYCNPLGSIHDRCNGS 435
EC+C+ + +RC S
Sbjct: 516 DECFCS---GVSNRCQSS 530
Score = 42.4 bits (98), Expect = 0.001
Identities = 44/160 (27%), Positives = 59/160 (36%), Gaps = 32/160 (20%)
Query: 387 CKHNTRGQHCELCRLGYFRNASAQLDDE-----NVCIECYCNPLGSIHDRCNGSGFCE-C 440
C G CE C G++R S C+ C CN S+ D + C+ C
Sbjct: 1382 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDP--ETSICQNC 1439
Query: 441 KTGTTGPKCDECLPGNSWHYG--------CQPNVC------DNELLHCQNGGTCHNNVRC 486
+ T G C+ C G +YG CQ C +N C G ++ RC
Sbjct: 1440 QHHTAGDFCERCALG---YYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGL--DDYRC 1494
Query: 487 L-CPAAYTGILCEKLRCEEAGSCGSDSGQ----GAPPHGS 521
CP Y G CE+ GS G+ G P+GS
Sbjct: 1495 TACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGS 1534
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 162 bits (409), Expect = 9e-40
Identities = 131/489 (26%), Positives = 212/489 (43%), Gaps = 87/489 (17%)
Query: 49 ACQPESTDM----TKYLKVKLDPPDITCG-DPPETFCAM-GNPYMCNNECDASTPE--LA 100
AC P D+ T++L+ TCG PET+C G M +CD+ P +
Sbjct: 25 ACYPPVGDLLVGRTRFLRASS-----TCGLTKPETYCTQYGEWQMKCCKCDSRQPHNYYS 79
Query: 101 HPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQM 160
H E + G P +WQS V++ L + +L + +++ F+ P M
Sbjct: 80 HRVENVASSSG--PMRWWQSQNDVN-----PVSLQLDLDRRFQLQE-VMMEFQGPMPAGM 131
Query: 161 ILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKI 220
++E+S D+G+TW+ YQY A DC F V+ + ++ C S N+++
Sbjct: 132 LIERSSDFGKTWRVYQYLAADCTSTF----PRVRQGRPQSWQDVRCQ---SLPQRPNARL 184
Query: 221 IHFEIKDRFAFFAGPRLRNMASLYGQLDTTK--KLRDFFTVTDLRIRLLRPAVGEIFVDE 278
+++ N+ L + T+ K+++ +T+LR+ R A +
Sbjct: 185 NGGKVQ-----------LNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLA--PVPQRG 231
Query: 279 LHLARYFYAISDIKVRGRCKCNLHATVC---------------VYDNSKLTCECEHNTTG 323
H +YA+S ++++G C C+ HA C V+D C C+HNT G
Sbjct: 232 YHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHD----VCVCQHNTAG 287
Query: 324 PDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTV- 382
P+C +C Y RPW P A+ C C+C GHS C + +
Sbjct: 288 PNCERCAPFYNNRPWRPAE-----GQDAHEC-------QRCDCNGHSETCHFDPAVFAAS 335
Query: 383 ------ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDR-CNG- 434
+C +C+ +T G++CE C+L YFRN + CI C C+P G++ C+
Sbjct: 336 QGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPV 395
Query: 435 SGFCECKTGTTGPKCDECLPGNSWHYGCQP---NVCDNELLHCQNGGTC-HNNVRCLCPA 490
+G C CK G +CD C PG + P + CD +L + C + RCLC
Sbjct: 396 TGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLP 455
Query: 491 AYTGILCEK 499
G C++
Sbjct: 456 NVVGPKCDQ 464
Score = 46.6 bits (109), Expect = 6e-05
Identities = 46/178 (25%), Positives = 62/178 (34%), Gaps = 33/178 (18%)
Query: 296 RCKCNLHATV--CVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANT 353
RC CN+ + D C C N GP C +C Y + S P N+
Sbjct: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNS 488
Query: 354 CIPSISSI-GNCECFGHSNRCSYIDLLNTVICV-SCKHNTRGQHCELCRLGYFRNASAQL 411
P + G C C R + L+ + + C T G CR
Sbjct: 489 LSPQCNQFTGQCPC-----REGFGGLMCSAAAIRQCPDRTYGDVATGCRA---------- 533
Query: 412 DDENVCIECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPGNSWHY----GCQP 464
C C+ G+ C+ SG C C+ G TGP+CD+C G Y C P
Sbjct: 534 --------CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHP 583
Score = 29.6 bits (65), Expect = 7.3
Identities = 19/54 (35%), Positives = 23/54 (42%), Gaps = 5/54 (9%)
Query: 453 LPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAA-----YTGILCEKLR 501
L GNS C P C EL NG C + R + P A G + E+LR
Sbjct: 787 LCGNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR 840
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 162 bits (409), Expect = 9e-40
Identities = 131/489 (26%), Positives = 212/489 (43%), Gaps = 87/489 (17%)
Query: 49 ACQPESTDM----TKYLKVKLDPPDITCG-DPPETFCAM-GNPYMCNNECDASTPE--LA 100
AC P D+ T++L+ TCG PET+C G M +CD+ P +
Sbjct: 25 ACYPPVGDLLVGRTRFLRASS-----TCGLTKPETYCTQYGEWQMKCCKCDSRQPHNYYS 79
Query: 101 HPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQM 160
H E + G P +WQS V++ L + +L + +++ F+ P M
Sbjct: 80 HRVENVASSSG--PMRWWQSQNDVN-----PVSLQLDLDRRFQLQE-VMMEFQGPMPAGM 131
Query: 161 ILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKI 220
++E+S D+G+TW+ YQY A DC F V+ + ++ C S N+++
Sbjct: 132 LIERSSDFGKTWRVYQYLAADCTSTF----PRVRQGRPQSWQDVRCQ---SLPQRPNARL 184
Query: 221 IHFEIKDRFAFFAGPRLRNMASLYGQLDTTK--KLRDFFTVTDLRIRLLRPAVGEIFVDE 278
+++ N+ L + T+ K+++ +T+LR+ R A +
Sbjct: 185 NGGKVQ-----------LNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLA--PVPQRG 231
Query: 279 LHLARYFYAISDIKVRGRCKCNLHATVC---------------VYDNSKLTCECEHNTTG 323
H +YA+S ++++G C C+ HA C V+D C C+HNT G
Sbjct: 232 YHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHD----VCVCQHNTAG 287
Query: 324 PDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTV- 382
P+C +C Y RPW P A+ C C+C GHS C + +
Sbjct: 288 PNCERCAPFYNNRPWRPAE-----GQDAHEC-------QRCDCNGHSETCHFDPAVFAAS 335
Query: 383 ------ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDR-CNG- 434
+C +C+ +T G++CE C+L YFRN + CI C C+P G++ C+
Sbjct: 336 QGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPV 395
Query: 435 SGFCECKTGTTGPKCDECLPGNSWHYGCQP---NVCDNELLHCQNGGTC-HNNVRCLCPA 490
+G C CK G +CD C PG + P + CD +L + C + RCLC
Sbjct: 396 TGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLP 455
Query: 491 AYTGILCEK 499
G C++
Sbjct: 456 NVVGPKCDQ 464
Score = 46.6 bits (109), Expect = 6e-05
Identities = 46/178 (25%), Positives = 62/178 (34%), Gaps = 33/178 (18%)
Query: 296 RCKCNLHATV--CVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANT 353
RC CN+ + D C C N GP C +C Y + S P N+
Sbjct: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNS 488
Query: 354 CIPSISSI-GNCECFGHSNRCSYIDLLNTVICV-SCKHNTRGQHCELCRLGYFRNASAQL 411
P + G C C R + L+ + + C T G CR
Sbjct: 489 LSPQCNQFTGQCPC-----REGFGGLMCSAAAIRQCPDRTYGDVATGCRA---------- 533
Query: 412 DDENVCIECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPGNSWHY----GCQP 464
C C+ G+ C+ SG C C+ G TGP+CD+C G Y C P
Sbjct: 534 --------CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHP 583
Score = 29.6 bits (65), Expect = 7.3
Identities = 19/54 (35%), Positives = 23/54 (42%), Gaps = 5/54 (9%)
Query: 453 LPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAA-----YTGILCEKLR 501
L GNS C P C EL NG C + R + P A G + E+LR
Sbjct: 787 LCGNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR 840
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 162 bits (409), Expect = 9e-40
Identities = 131/489 (26%), Positives = 212/489 (43%), Gaps = 87/489 (17%)
Query: 49 ACQPESTDM----TKYLKVKLDPPDITCG-DPPETFCAM-GNPYMCNNECDASTPE--LA 100
AC P D+ T++L+ TCG PET+C G M +CD+ P +
Sbjct: 25 ACYPPVGDLLVGRTRFLRASS-----TCGLTKPETYCTQYGEWQMKCCKCDSRQPHNYYS 79
Query: 101 HPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQM 160
H E + G P +WQS V++ L + +L + +++ F+ P M
Sbjct: 80 HRVENVASSSG--PMRWWQSQNDVN-----PVSLQLDLDRRFQLQE-VMMEFQGPMPAGM 131
Query: 161 ILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKI 220
++E+S D+G+TW+ YQY A DC F V+ + ++ C S N+++
Sbjct: 132 LIERSSDFGKTWRVYQYLAADCTSTF----PRVRQGRPQSWQDVRCQ---SLPQRPNARL 184
Query: 221 IHFEIKDRFAFFAGPRLRNMASLYGQLDTTK--KLRDFFTVTDLRIRLLRPAVGEIFVDE 278
+++ N+ L + T+ K+++ +T+LR+ R A +
Sbjct: 185 NGGKVQ-----------LNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLA--PVPQRG 231
Query: 279 LHLARYFYAISDIKVRGRCKCNLHATVC---------------VYDNSKLTCECEHNTTG 323
H +YA+S ++++G C C+ HA C V+D C C+HNT G
Sbjct: 232 YHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHD----VCVCQHNTAG 287
Query: 324 PDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTV- 382
P+C +C Y RPW P A+ C C+C GHS C + +
Sbjct: 288 PNCERCAPFYNNRPWRPAE-----GQDAHEC-------QRCDCNGHSETCHFDPAVFAAS 335
Query: 383 ------ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDR-CNG- 434
+C +C+ +T G++CE C+L YFRN + CI C C+P G++ C+
Sbjct: 336 QGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPV 395
Query: 435 SGFCECKTGTTGPKCDECLPGNSWHYGCQP---NVCDNELLHCQNGGTC-HNNVRCLCPA 490
+G C CK G +CD C PG + P + CD +L + C + RCLC
Sbjct: 396 TGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLP 455
Query: 491 AYTGILCEK 499
G C++
Sbjct: 456 NVVGPKCDQ 464
Score = 46.6 bits (109), Expect = 6e-05
Identities = 46/178 (25%), Positives = 62/178 (34%), Gaps = 33/178 (18%)
Query: 296 RCKCNLHATV--CVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANT 353
RC CN+ + D C C N GP C +C Y + S P N+
Sbjct: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNS 488
Query: 354 CIPSISSI-GNCECFGHSNRCSYIDLLNTVICV-SCKHNTRGQHCELCRLGYFRNASAQL 411
P + G C C R + L+ + + C T G CR
Sbjct: 489 LSPQCNQFTGQCPC-----REGFGGLMCSAAAIRQCPDRTYGDVATGCRA---------- 533
Query: 412 DDENVCIECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPGNSWHY----GCQP 464
C C+ G+ C+ SG C C+ G TGP+CD+C G Y C P
Sbjct: 534 --------CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHP 583
Score = 29.6 bits (65), Expect = 7.3
Identities = 19/54 (35%), Positives = 23/54 (42%), Gaps = 5/54 (9%)
Query: 453 LPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAA-----YTGILCEKLR 501
L GNS C P C EL NG C + R + P A G + E+LR
Sbjct: 787 LCGNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR 840
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 160 bits (406), Expect = 2e-39
Identities = 129/496 (26%), Positives = 217/496 (43%), Gaps = 82/496 (16%)
Query: 49 ACQPESTDMTKYLKVKLDPPDITCG-DPPETFCAMGNP------YMCNNECDASTPELAH 101
+C P + D+ +L TCG + P+ +C + + ++C++ S + H
Sbjct: 46 SCYPATGDLLVGRADRLTASS-TCGLNGPQPYCIVSHLQDEKKCFLCDSRRPFSARDNPH 104
Query: 102 PPEL---MFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPD 158
+ + F + + +WQS E P V I L T ++++TF++ RP
Sbjct: 105 SHRIQNVVTSFAPQRRAAWWQS----ENGIPA-VTIQLDLEAEFHFT-HLIMTFKTFRPA 158
Query: 159 QMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNS 218
M++E+S D+GRTW Y+Y++ DC F P + +H +++C YS +
Sbjct: 159 AMLVERSADFGRTWHVYRYFSYDCGADFPGVPLAPP---RHWD-DVVCESRYSEIEPSTE 214
Query: 219 KIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLR-PAVGEIFVD 277
+ + + D P + ++++ +T+LR+ L R +G+ +D
Sbjct: 215 GEVIYRVLDPAIPIPDPY-------------SSRIQNLLKITNLRVNLTRLHTLGDNLLD 261
Query: 278 ELHLAR--YFYAISDIKVRGRCKCNLHATVCVYDNSKLT---------CECEHNTTGPDC 326
R Y+YA+ ++ VRG C C HA+ C C C+HNT G +C
Sbjct: 262 PRREIREKYYYALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNC 321
Query: 327 GKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDL-------- 378
+C+ Y+ PW P G ++ C CEC GH++ C + D+
Sbjct: 322 EQCQDFYRDLPWRPAE-----DGHSHAC-------RKCECHGHTHSCHF-DMAVYLASGN 368
Query: 379 LNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIH-DRCNG--- 434
++ +C C+HNT G+HCELCR ++R+ + L D VC C C+P+GS RC+
Sbjct: 369 VSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDD 428
Query: 435 ------SGFCECKTGTTGPKCDECLPG-----NSWHYGCQPNVCDNELLHCQNGGTCHNN 483
SG C CK G +C +C G S GC+ C+ + N+
Sbjct: 429 PALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNS 488
Query: 484 VRCLCPAAYTGILCEK 499
C C TG C++
Sbjct: 489 GSCYCKRLVTGRGCDR 504
Score = 86.7 bits (213), Expect = 5e-17
Identities = 63/218 (28%), Positives = 87/218 (39%), Gaps = 43/218 (19%)
Query: 303 ATVCVYD--NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
AT C D + ++ C C TG C C + G P PG + + C +I
Sbjct: 940 ATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCE-----CSGNIDP 994
Query: 361 IGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIEC 420
+ C H+ +C + C H+T G HC C+ G+ A+ Q C C
Sbjct: 995 MDPDACDPHTGQC-----------LRCLHHTEGPHCAHCKPGFHGQAARQ-----SCHRC 1038
Query: 421 YCNPLGSIHDRC---------NGSGFCECKTGTTGPKCDECLPGNSWH----YGCQPNVC 467
CN LG+ +C SG C C GP CD C P N W+ +GCQP C
Sbjct: 1039 TCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAP-NFWNLTSGHGCQPCAC 1097
Query: 468 DNELLHCQNGGTCHN-NVRCLCPAAYTGILCEKLRCEE 504
G TC+ +C C A + G C + C+E
Sbjct: 1098 HPSR---ARGPTCNEFTGQCHCRAGFGGRTCSE--CQE 1130
Score = 64.3 bits (155), Expect = 3e-10
Identities = 53/216 (24%), Positives = 84/216 (38%), Gaps = 46/216 (21%)
Query: 297 CKCNLHATVC-VYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
C+C+ + + + + C C G C +C++ G P +C
Sbjct: 831 CQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFP---------------SCR 875
Query: 356 PSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDEN 415
P C C GH++ C+ +T C+ C+ +T G+HCE C G+ + +L
Sbjct: 876 P-------CVCNGHADECN----THTGACLGCRDHTGGEHCERCIAGF--HGDPRLPYGG 922
Query: 416 VCIECYC--NPLGSIH-------DRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNV 466
C C C P H D + C C+ G TG +C+ C PG H+G P+
Sbjct: 923 QCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPG---HFG-DPSR 978
Query: 467 CDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRC 502
C+ C N+ + P A + LRC
Sbjct: 979 PGGRCQLCE----CSGNIDPMDPDACDPHTGQCLRC 1010
Score = 62.8 bits (151), Expect = 8e-10
Identities = 52/210 (24%), Positives = 76/210 (36%), Gaps = 43/210 (20%)
Query: 299 CNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTAN---TCI 355
C+ H C+ C H+T GP C CK + G+ + + T N T
Sbjct: 1000 CDPHTGQCL--------RCLHHTEGPHCAHCKPGFHGQAARQSCH----RCTCNLLGTNP 1047
Query: 356 PSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDEN 415
S C C S +C C N +G C+ C ++ S +
Sbjct: 1048 QQCPSPDQCHCDPSSGQCP------------CLPNVQGPSCDRCAPNFWNLTSG-----H 1090
Query: 416 VCIECYCNPLGSIHDRCNG-SGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHC 474
C C C+P + CN +G C C+ G G C EC + G Q + CD C
Sbjct: 1091 GCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACD-----C 1145
Query: 475 QNGG----TCHN-NVRCLCPAAYTGILCEK 499
+ G CH C C +G+ C++
Sbjct: 1146 DSRGIDTPQCHRFTGHCSCRPGVSGVRCDQ 1175
Score = 58.5 bits (140), Expect = 1e-08
Identities = 33/95 (34%), Positives = 45/95 (47%), Gaps = 13/95 (13%)
Query: 415 NVCIECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLH 473
N + C CNP GS+ CN G C CK G G +CD C PG +YG P C +
Sbjct: 778 NGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPG---YYGFGPTGC--QACQ 832
Query: 474 CQNGGTCHN-----NVRCLCPAAYTGILCEKLRCE 503
C + G + + +CLC G+ C+ RC+
Sbjct: 833 CSHEGALSSLCEKTSGQCLCRTGAFGLRCD--RCQ 865
Score = 57.4 bits (137), Expect = 3e-08
Identities = 35/118 (29%), Positives = 47/118 (39%), Gaps = 20/118 (16%)
Query: 365 ECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNP 424
EC H +C CK G+ C+LC GY+ C C C+
Sbjct: 794 ECNPHGGQCL------------CKPGVVGRRCDLCAPGYYGFGPTG------CQACQCSH 835
Query: 425 LGSIHDRCNG-SGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQ-NGGTC 480
G++ C SG C C+TG G +CD C G C+P VC+ C + G C
Sbjct: 836 EGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGAC 893
Score = 54.7 bits (130), Expect = 2e-07
Identities = 46/180 (25%), Positives = 66/180 (36%), Gaps = 38/180 (21%)
Query: 296 RCKCNLHAT---------VCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPI 346
RC CNL T C D S C C N GP C +C N+ G
Sbjct: 1037 RCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQ--- 1093
Query: 347 PKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRN 406
C PS + C F + +C C+ G+ C C+ ++ +
Sbjct: 1094 ----PCACHPSRARGPTCNEF--TGQCH------------CRAGFGGRTCSECQELHWGD 1135
Query: 407 ASAQLDDENVCIECYCNPLGSIHDRCNG-SGFCECKTGTTGPKCDECLPGNSWHY-GCQP 464
Q C C C+ G +C+ +G C C+ G +G +CD+C G S + C P
Sbjct: 1136 PGLQ------CHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHP 1189
Score = 47.0 bits (110), Expect = 4e-05
Identities = 33/142 (23%), Positives = 57/142 (40%), Gaps = 22/142 (15%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCS 374
C C+ + G C +C+ + G S + A +P G+ C +S C
Sbjct: 438 CRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVP-----GSTPCDPNSGSCY 492
Query: 375 YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCN- 433
CK G+ C+ C G++ + L C C C+ G++ +C+
Sbjct: 493 ------------CKRLVTGRGCDRCLPGHWGLSHDLLG----CRPCDCDVGGALDPQCDE 536
Query: 434 GSGFCECKTGTTGPKCDECLPG 455
G+G C C+ G +C++ PG
Sbjct: 537 GTGQCHCRQHMVGRRCEQVQPG 558
Score = 34.3 bits (77), Expect = 0.30
Identities = 29/122 (23%), Positives = 45/122 (36%), Gaps = 23/122 (18%)
Query: 287 AISDIKVRGRCKCNLHATV---CVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSY 343
+ISD RC+CN TV D + +C C+ TG C +C + G
Sbjct: 460 SISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGC 519
Query: 344 LPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGY 403
P C + + +C + +C C+ + G+ CE + GY
Sbjct: 520 RP--------CDCDVGGALDPQCDEGTGQCH------------CRQHMVGRRCEQVQPGY 559
Query: 404 FR 405
FR
Sbjct: 560 FR 561
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 159 bits (403), Expect = 5e-39
Identities = 141/538 (26%), Positives = 227/538 (42%), Gaps = 101/538 (18%)
Query: 25 LVWGHYDLCKTQIYTEEGKVWDYMA---CQPESTDMTKYLKVKLDPPDITCG-DPPETFC 80
L + LC+ ++ +E + A C P + D+ KL TCG PE +C
Sbjct: 7 LAFSFLALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTS-TCGLHKPEPYC 65
Query: 81 AMGNP------YMCNNEC---DASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQ 131
+ + ++CN++ + P+ ++ F +WQS E
Sbjct: 66 IVSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVE-----N 120
Query: 132 VNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPK 191
V I L T ++++TF++ RP M++E+S D+G+TW Y+Y+A DC +F
Sbjct: 121 VTIQLDLEAEFHFT-HLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFAYDCEASF----P 175
Query: 192 SVKDLSQHTVLEIICTEEYST-GYTTNSKIIH------FEIKDRFAFFAGPRLRNMASLY 244
+ V +IIC YS +T ++I F+I+D ++ PR++N+
Sbjct: 176 GISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYS----PRIQNLLK-- 229
Query: 245 GQLDTTKKLRDFFTVTDLRIRLLR-PAVGEIFVDELHLAR--YFYAISDIKVRGRCKCNL 301
+T+LRI+ ++ +G+ +D R Y+YA+ D+ VRG C C
Sbjct: 230 --------------ITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYG 275
Query: 302 HATVCVYD---NSKLT------CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTAN 352
HA+ C N ++ C C HNT G +C C Y PW P +N
Sbjct: 276 HASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAE-----GRNSN 330
Query: 353 TCIPSISSIGNCECFGHSNRCSYIDL--------LNTVICVSCKHNTRGQHCELCRLGYF 404
C C C HS C + D+ ++ +C C+HNT G++CE C+ Y+
Sbjct: 331 AC-------KKCNCNEHSISCHF-DMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYY 382
Query: 405 RNASAQLDDENVCIECYCNPLGSIHDR-CNG---------SGFCECKTGTTGPKCDECLP 454
++ + D N C C C+P GS ++ C+ +G C CK G CD C
Sbjct: 383 QHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKE 442
Query: 455 G-----NSWHYGCQPNVCDNELLHCQNGGTCHNNV-RCLCPAAYTGILCEKLRCEEAG 506
G + +GC+ C N L G C + C C TG C++ E G
Sbjct: 443 GFYDLSSEDPFGCKSCAC-NPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWG 499
Score = 89.0 bits (219), Expect = 1e-17
Identities = 64/213 (30%), Positives = 89/213 (41%), Gaps = 54/213 (25%)
Query: 312 KLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSN 371
+L C C+ G C C Y G P G +C P C+C H+N
Sbjct: 941 QLACVCDPGYIGSRCDDCASGYFGNPSEVGG----------SCQP-------CQC--HNN 981
Query: 372 RCSYIDLLN-------TVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNP 424
ID + T C+ C ++T G+HC+ CR GY+ +A Q C +C CN
Sbjct: 982 ----IDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQ-----DCRKCVCNY 1032
Query: 425 LGSIHDRCNGS--------GFCECKTGTTGPKCDECLPGNSWHY----GCQPNVCDNELL 472
LG++ + CNGS G C C G CD C P N+W GC P C+
Sbjct: 1033 LGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAP-NTWQLASGTGCDP--CNCNAA 1089
Query: 473 HCQNGGTCHN-NVRCLCPAAYTGILCEKLRCEE 504
H G +C+ +C C + G C + C+E
Sbjct: 1090 H-SFGPSCNEFTGQCQCMPGFGGRTCSE--CQE 1119
Score = 64.7 bits (156), Expect = 2e-10
Identities = 52/167 (31%), Positives = 68/167 (40%), Gaps = 28/167 (16%)
Query: 364 CECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCN 423
CEC + S D N C C+ N G+ C C G F + C C C+
Sbjct: 773 CECDPQGSLSSVCDP-NGGQC-QCRPNVVGRTCNRCAPGTFGFGPSG------CKPCECH 824
Query: 424 PLGSIHDRCNG-SGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCD----------NELL 472
GS++ CN +G C C G +CD CLPG+ CQP C+ E L
Sbjct: 825 LQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGECL 884
Query: 473 HCQNGGTCHNNVRCLC-----PAAYTGILCEKLRCEEAGSCGSDSGQ 514
+CQ+ HN RCL P +G C C + G DSG+
Sbjct: 885 NCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPD----GPDSGR 927
Score = 62.8 bits (151), Expect = 8e-10
Identities = 63/251 (25%), Positives = 89/251 (35%), Gaps = 65/251 (25%)
Query: 297 CKCNLHATVC-VYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIP---KGTAN 352
C+C+ ++ V D + C+C N G C +C G + P P +G+ N
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFG--FGPSGCKPCECHLQGSVN 830
Query: 353 T----------------------CIP---SISSIGNCECFGHSNRCSYIDLLNTVICVSC 387
C+P S C+C GH++ C + T C++C
Sbjct: 831 AFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPV----TGECLNC 886
Query: 388 KHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLG----------SIHDRCNGSGF 437
+ T G +CE C GY+ + D C C C P G D
Sbjct: 887 QDYTMGHNCERCLAGYYGDPIIGSGDH--CRPCPC-PDGPDSGRQFARSCYQDPVTLQLA 943
Query: 438 CECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILC 497
C C G G +CD+C G Y P+ CQ CHNN+ P A C
Sbjct: 944 CVCDPGYIGSRCDDCASG----YFGNPSEVGGSCQPCQ----CHNNIDTTDPEA-----C 990
Query: 498 EKLRCEEAGSC 508
+K E G C
Sbjct: 991 DK----ETGRC 997
Score = 50.4 bits (119), Expect = 4e-06
Identities = 47/176 (26%), Positives = 62/176 (35%), Gaps = 46/176 (26%)
Query: 296 RCKCNLHATV--------CVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYL--- 344
+C CN TV C D + C C N G +C +C N W S
Sbjct: 1027 KCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPN----TWQLASGTGCD 1082
Query: 345 PIPKGTANTCIPSISSI-GNCECF-GHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLG 402
P A++ PS + G C+C G R C C+ G
Sbjct: 1083 PCNCNAAHSFGPSCNEFTGQCQCMPGFGGRT----------CSECQELFWG--------- 1123
Query: 403 YFRNASAQLDDENVCIECYCNPLGSIHDRCNGS-GFCECKTGTTGPKCDECLPGNS 457
D + C C C+P G +C+ S G C C G GP+CD+C G S
Sbjct: 1124 ---------DPDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYS 1170
Score = 43.5 bits (101), Expect = 5e-04
Identities = 30/113 (26%), Positives = 44/113 (38%), Gaps = 17/113 (15%)
Query: 418 IECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPGNSWH--YGCQPNVCDNE---- 470
+ C C+P GS+ C+ G C+C+ G C+ C PG GC+P C +
Sbjct: 771 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVN 830
Query: 471 --------LLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCE-EAGSCGSDSGQ 514
HC G RCL P + C+ +C A C +G+
Sbjct: 831 AFCNPVTGQCHCFQGVYARQCDRCL-PGHWGFPSCQPCQCNGHADDCDPVTGE 882
Score = 31.2 bits (69), Expect = 2.5
Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 6/54 (11%)
Query: 285 FYAISDIKVRGRCKCN---LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQG 335
F+ D++ R C C+ + C D S C C GP C KC + Y G
Sbjct: 1121 FWGDPDVECRA-CDCDPRGIETPQC--DQSTGQCVCVEGVEGPRCDKCTRGYSG 1171
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 127 bits (320), Expect = 2e-29
Identities = 105/382 (27%), Positives = 163/382 (42%), Gaps = 70/382 (18%)
Query: 148 IVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQH---TVLEI 204
I+I F S +P ++ +++ + W+ +QY+A +C AF M K+ DL + L++
Sbjct: 385 IIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC-GAFGM--KNNGDLEKPDSVNCLQL 441
Query: 205 ICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRI 264
YS G T S + GP R Y T L++F T +R
Sbjct: 442 SNFTPYSRGNVTFSILT-----------PGPNYRPG---YNNFYNTPSLQEFVKATQIRF 487
Query: 265 RLLRPAVGEIFVDE--LHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCEC--EHN 320
G+ + E ++L +YA+ +I + GRC+C+ HA C + C C E
Sbjct: 488 HFH----GQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQESF 543
Query: 321 TTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLN 380
T G C +C Y +P+ G + A C P C+C HS C Y ++
Sbjct: 544 TEGLHCDRCLPLYNDKPFRQGDQV-----YAFNCKP-------CQCNSHSKSCHYNISVD 591
Query: 381 TV----------ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHD 430
+C C+HNT G++CELC+ +FR A +VC C C+ +G+
Sbjct: 592 PFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGT--- 648
Query: 431 RCNGS-------GFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGG----- 478
NGS G C CK +G +C++C G P+ C +C G
Sbjct: 649 -RNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSP--CNCNTSGTVDGD 705
Query: 479 -TCH-NNVRCLCPAAYTGILCE 498
TCH N+ +C C A G+ C+
Sbjct: 706 ITCHQNSGQCKCKANVIGLRCD 727
Score = 73.9 bits (180), Expect = 3e-13
Identities = 60/215 (27%), Positives = 90/215 (41%), Gaps = 40/215 (18%)
Query: 297 CKCNLHATVCVYDNSKL-TCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
C+CNLH +V + N CEC+ G C C++N+ G L + A C
Sbjct: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG--------LDVTNCKACDC- 797
Query: 356 PSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDEN 415
+ S+ C + +C CK N G+ C C G F + ++
Sbjct: 798 DTAGSLPGTVCNAKTGQCI------------CKPNVEGRQCNKCLEGNFY---LRQNNSF 842
Query: 416 VCIECYCNPLGSIHDR--CNGS-GFCECKTGTTGPKCDECLP-------GNSWHYGCQPN 465
+C+ C C+ G+I+ CN S G C CK G TG +C++C P N H CQ
Sbjct: 843 LCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQH--CQ-- 898
Query: 466 VCDNELLHCQNGGTCHN-NVRCLCPAAYTGILCEK 499
+C+ + L G C + +CLC G C +
Sbjct: 899 MCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQ 933
Score = 62.8 bits (151), Expect = 8e-10
Identities = 54/182 (29%), Positives = 77/182 (42%), Gaps = 34/182 (18%)
Query: 283 RYFYAISDIKVRGRCKCN----LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPW 338
RY I + + C+C+ L T+C D C C N G C +C+
Sbjct: 886 RYNLTIDNFQHCQMCECDSLGTLPGTIC--DPISGQCLCVPNRQGRRCNQCQ-------- 935
Query: 339 SPGSYLPIPKGTANTCIPSISSIGNCECFGHSNR-CSYIDLLNTVICVSCKHNTRGQHCE 397
PG Y I G A C+P +C G N C+ + T CV + GQ C+
Sbjct: 936 -PGFY--ISPGNATGCLPC-----SCHTTGAVNHICNSL----TGQCVCQDASIAGQRCD 983
Query: 398 LCRLGYFRNASAQLDDENV-CIECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPG 455
C+ YF D + C C C+ G++++ C+ +G C CK TG KCD C+P
Sbjct: 984 QCKDHYFG-----FDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPS 1038
Query: 456 NS 457
S
Sbjct: 1039 AS 1040
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 127 bits (320), Expect = 2e-29
Identities = 105/382 (27%), Positives = 163/382 (42%), Gaps = 70/382 (18%)
Query: 148 IVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQH---TVLEI 204
I+I F S +P ++ +++ + W+ +QY+A +C AF M K+ DL + L++
Sbjct: 385 IIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC-GAFGM--KNNGDLEKPDSVNCLQL 441
Query: 205 ICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRI 264
YS G T S + GP R Y T L++F T +R
Sbjct: 442 SNFTPYSRGNVTFSILT-----------PGPNYRPG---YNNFYNTPSLQEFVKATQIRF 487
Query: 265 RLLRPAVGEIFVDE--LHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCEC--EHN 320
G+ + E ++L +YA+ +I + GRC+C+ HA C + C C E
Sbjct: 488 HFH----GQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQESF 543
Query: 321 TTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLN 380
T G C +C Y +P+ G + A C P C+C HS C Y ++
Sbjct: 544 TEGLHCDRCLPLYNDKPFRQGDQV-----YAFNCKP-------CQCNSHSKSCHYNISVD 591
Query: 381 TV----------ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHD 430
+C C+HNT G++CELC+ +FR A +VC C C+ +G+
Sbjct: 592 PFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGT--- 648
Query: 431 RCNGS-------GFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGG----- 478
NGS G C CK +G +C++C G P+ C +C G
Sbjct: 649 -RNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSP--CNCNTSGTVDGD 705
Query: 479 -TCH-NNVRCLCPAAYTGILCE 498
TCH N+ +C C A G+ C+
Sbjct: 706 ITCHQNSGQCKCKANVIGLRCD 727
Score = 73.9 bits (180), Expect = 3e-13
Identities = 60/215 (27%), Positives = 90/215 (41%), Gaps = 40/215 (18%)
Query: 297 CKCNLHATVCVYDNSKL-TCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
C+CNLH +V + N CEC+ G C C++N+ G L + A C
Sbjct: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG--------LDVTNCKACDC- 797
Query: 356 PSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDEN 415
+ S+ C + +C CK N G+ C C G F + ++
Sbjct: 798 DTAGSLPGTVCNAKTGQCI------------CKPNVEGRQCNKCLEGNFY---LRQNNSF 842
Query: 416 VCIECYCNPLGSIHDR--CNGS-GFCECKTGTTGPKCDECLP-------GNSWHYGCQPN 465
+C+ C C+ G+I+ CN S G C CK G TG +C++C P N H CQ
Sbjct: 843 LCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQH--CQ-- 898
Query: 466 VCDNELLHCQNGGTCHN-NVRCLCPAAYTGILCEK 499
+C+ + L G C + +CLC G C +
Sbjct: 899 MCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQ 933
Score = 62.8 bits (151), Expect = 8e-10
Identities = 54/182 (29%), Positives = 77/182 (42%), Gaps = 34/182 (18%)
Query: 283 RYFYAISDIKVRGRCKCN----LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPW 338
RY I + + C+C+ L T+C D C C N G C +C+
Sbjct: 886 RYNLTIDNFQHCQMCECDSLGTLPGTIC--DPISGQCLCVPNRQGRRCNQCQ-------- 935
Query: 339 SPGSYLPIPKGTANTCIPSISSIGNCECFGHSNR-CSYIDLLNTVICVSCKHNTRGQHCE 397
PG Y I G A C+P +C G N C+ + T CV + GQ C+
Sbjct: 936 -PGFY--ISPGNATGCLPC-----SCHTTGAVNHICNSL----TGQCVCQDASIAGQRCD 983
Query: 398 LCRLGYFRNASAQLDDENV-CIECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPG 455
C+ YF D + C C C+ G++++ C+ +G C CK TG KCD C+P
Sbjct: 984 QCKDHYFG-----FDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPS 1038
Query: 456 NS 457
S
Sbjct: 1039 AS 1040
>gi|24308065 netrin 5 [Homo sapiens]
Length = 489
Score = 122 bits (307), Expect = 6e-28
Identities = 59/171 (34%), Positives = 87/171 (50%), Gaps = 20/171 (11%)
Query: 293 VRGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTAN 352
+RGRC+C+ HA C C C H+TTGP C C+ +++ PW P + P+ +
Sbjct: 153 LRGRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPAT----PR-HPH 207
Query: 353 TCIPSISSIGNCECFGHSNRCSYIDLLNTV-------ICVSCKHNTRGQHCELCRLGYFR 405
C+P C C H+ RC + L + +C C+H+T G+HC C+ G++R
Sbjct: 208 PCLP-------CSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWR 260
Query: 406 NASAQLDDENVCIECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPG 455
+ S + C C C+P+G+ CN SG C CK G TG C+ C PG
Sbjct: 261 DPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPG 311
Score = 33.5 bits (75), Expect = 0.51
Identities = 21/79 (26%), Positives = 31/79 (39%), Gaps = 15/79 (18%)
Query: 438 CECKTGTTGPKCDECLPGN---SWH-------YGCQPNVCDNELLHCQNGGTCHNNVRCL 487
C C+ TTGP C+ C P + W + C P C+ C+ N+
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCR-----FNSELFR 229
Query: 488 CPAAYTGILCEKLRCEEAG 506
+G +CE+ R AG
Sbjct: 230 LSGGRSGGVCERCRHHTAG 248
Score = 29.6 bits (65), Expect = 7.3
Identities = 24/102 (23%), Positives = 42/102 (41%), Gaps = 11/102 (10%)
Query: 297 CKCN-LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQ--GRPWSPGSYLPIPKGTANT 353
C+C+ + AT + + C C+ TG C +C YQ P P +P T T
Sbjct: 275 CQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPCQRIPEATTTLAT 334
Query: 354 CIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQH 395
+ SS C+ +Y ++ +T + +S + + H
Sbjct: 335 TPGAYSSDPQCQ--------NYCNMSDTRVHMSLRRYCQQDH 368
>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
Length = 1111
Score = 95.5 bits (236), Expect = 1e-19
Identities = 56/153 (36%), Positives = 76/153 (49%), Gaps = 25/153 (16%)
Query: 364 CECFGHSNRCSYIDLL-----NTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCI 418
C+C G S +C + L N C++C NT G HCE C+ G++R+ + + C+
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR-----ERDRCL 82
Query: 419 ECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHY----GCQPNVCDNELL-- 472
C CN GS+ RC+ SG C CK G TG +CD CLPG +H GC D LL
Sbjct: 83 PCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPG--FHMLTDAGCTQ---DQRLLDS 137
Query: 473 --HCQNGGTCH--NNVRCLCPAAYTGILCEKLR 501
C G + RC+C A TG C++ R
Sbjct: 138 KCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCR 170
Score = 75.5 bits (184), Expect = 1e-13
Identities = 51/160 (31%), Positives = 69/160 (43%), Gaps = 24/160 (15%)
Query: 297 CKCNLHATVCVY-DNSKLTCE-CEHNTTGPDCGKCKKNYQGRPWSPGSYLPI----PKGT 350
C C+ + V + ++ C C TG C C Y G P+ G + P+ P
Sbjct: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQC 519
Query: 351 ANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQ 410
N PS S GNC+ T C+ C HNT G +C+ C+ GYF + A
Sbjct: 520 NNNVDPSAS--GNCDRL-------------TGRCLKCIHNTAGIYCDQCKAGYFGDPLAP 564
Query: 411 LDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCD 450
+ + C C CNP+GS C G C CK G GP C+
Sbjct: 565 -NPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE 603
Score = 61.2 bits (147), Expect = 2e-09
Identities = 52/182 (28%), Positives = 68/182 (37%), Gaps = 36/182 (19%)
Query: 297 CKCNLHATVCVYD--------NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPK 348
C CN + C++D N C NT G C KCK +
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR----------- 76
Query: 349 GTANTCIPSISSIGNCECFGH-SNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGY--FR 405
+ C+P NC G S RC N+ C SCK G C+ C G+
Sbjct: 77 -ERDRCLPC-----NCNSKGSLSARCD-----NSGRC-SCKPGVTGARCDRCLPGFHMLT 124
Query: 406 NASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPN 465
+A D + +C C+P G I C+ +G C CK TG +CD C G G P
Sbjct: 125 DAGCTQDQRLLDSKCDCDPAG-IAGPCD-AGRCVCKPAVTGERCDRCRSGYYNLDGGNPE 182
Query: 466 VC 467
C
Sbjct: 183 GC 184
Score = 48.1 bits (113), Expect = 2e-05
Identities = 50/211 (23%), Positives = 66/211 (31%), Gaps = 61/211 (28%)
Query: 314 TCECEHNTTGPD--CGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSN 371
T +C PD C C + P P S P P C S
Sbjct: 428 TGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCP------CHNGFS------------ 469
Query: 372 RCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRN-----------------------AS 408
CS + V+C +C G CELC GYF + AS
Sbjct: 470 -CSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSAS 528
Query: 409 AQLDD-ENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVC 467
D C++C N G D+C F + KC C C P
Sbjct: 529 GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRAC--------NCNP--M 578
Query: 468 DNELLHCQNGGTCHNNVRCLCPAAYTGILCE 498
+E + C++ GT C+C + G CE
Sbjct: 579 GSEPVGCRSDGT------CVCKPGFGGPNCE 603
Score = 43.9 bits (102), Expect = 4e-04
Identities = 43/144 (29%), Positives = 57/144 (39%), Gaps = 30/144 (20%)
Query: 387 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFC-----ECK 441
C +GQ C+ C GY R+ SA+L CI C C G G C +C
Sbjct: 384 CPVGYKGQFCQDCASGYKRD-SARLGPFGTCIPC----------NCQGGGACDPDTGDCY 432
Query: 442 TGTTGP--KCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCH-----NNVRC-LCPAAYT 493
+G P +C +C P ++ P C + C NG +C V C CP T
Sbjct: 433 SGDENPDIECADC-PIGFYNDPHDPRSC--KPCPCHNGFSCSVMPETEEVVCNNCPPGVT 489
Query: 494 GILCEKLRCEEAGSCGSDSGQGAP 517
G CE C + G G G+ P
Sbjct: 490 GARCE--LCAD-GYFGDPFGEHGP 510
>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
Length = 1193
Score = 95.5 bits (236), Expect = 1e-19
Identities = 56/153 (36%), Positives = 76/153 (49%), Gaps = 25/153 (16%)
Query: 364 CECFGHSNRCSYIDLL-----NTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCI 418
C+C G S +C + L N C++C NT G HCE C+ G++R+ + + C+
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR-----ERDRCL 82
Query: 419 ECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHY----GCQPNVCDNELL-- 472
C CN GS+ RC+ SG C CK G TG +CD CLPG +H GC D LL
Sbjct: 83 PCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPG--FHMLTDAGCTQ---DQRLLDS 137
Query: 473 --HCQNGGTCH--NNVRCLCPAAYTGILCEKLR 501
C G + RC+C A TG C++ R
Sbjct: 138 KCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCR 170
Score = 75.5 bits (184), Expect = 1e-13
Identities = 51/160 (31%), Positives = 69/160 (43%), Gaps = 24/160 (15%)
Query: 297 CKCNLHATVCVY-DNSKLTCE-CEHNTTGPDCGKCKKNYQGRPWSPGSYLPI----PKGT 350
C C+ + V + ++ C C TG C C Y G P+ G + P+ P
Sbjct: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQC 519
Query: 351 ANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQ 410
N PS S GNC+ T C+ C HNT G +C+ C+ GYF + A
Sbjct: 520 NNNVDPSAS--GNCDRL-------------TGRCLKCIHNTAGIYCDQCKAGYFGDPLAP 564
Query: 411 LDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCD 450
+ + C C CNP+GS C G C CK G GP C+
Sbjct: 565 -NPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE 603
Score = 61.2 bits (147), Expect = 2e-09
Identities = 52/182 (28%), Positives = 68/182 (37%), Gaps = 36/182 (19%)
Query: 297 CKCNLHATVCVYD--------NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPK 348
C CN + C++D N C NT G C KCK +
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR----------- 76
Query: 349 GTANTCIPSISSIGNCECFGH-SNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGY--FR 405
+ C+P NC G S RC N+ C SCK G C+ C G+
Sbjct: 77 -ERDRCLPC-----NCNSKGSLSARCD-----NSGRC-SCKPGVTGARCDRCLPGFHMLT 124
Query: 406 NASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPN 465
+A D + +C C+P G I C+ +G C CK TG +CD C G G P
Sbjct: 125 DAGCTQDQRLLDSKCDCDPAG-IAGPCD-AGRCVCKPAVTGERCDRCRSGYYNLDGGNPE 182
Query: 466 VC 467
C
Sbjct: 183 GC 184
Score = 48.1 bits (113), Expect = 2e-05
Identities = 50/211 (23%), Positives = 66/211 (31%), Gaps = 61/211 (28%)
Query: 314 TCECEHNTTGPD--CGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSN 371
T +C PD C C + P P S P P C S
Sbjct: 428 TGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCP------CHNGFS------------ 469
Query: 372 RCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRN-----------------------AS 408
CS + V+C +C G CELC GYF + AS
Sbjct: 470 -CSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSAS 528
Query: 409 AQLDD-ENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVC 467
D C++C N G D+C F + KC C C P
Sbjct: 529 GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRAC--------NCNP--M 578
Query: 468 DNELLHCQNGGTCHNNVRCLCPAAYTGILCE 498
+E + C++ GT C+C + G CE
Sbjct: 579 GSEPVGCRSDGT------CVCKPGFGGPNCE 603
Score = 43.9 bits (102), Expect = 4e-04
Identities = 43/144 (29%), Positives = 57/144 (39%), Gaps = 30/144 (20%)
Query: 387 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFC-----ECK 441
C +GQ C+ C GY R+ SA+L CI C C G G C +C
Sbjct: 384 CPVGYKGQFCQDCASGYKRD-SARLGPFGTCIPC----------NCQGGGACDPDTGDCY 432
Query: 442 TGTTGP--KCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCH-----NNVRC-LCPAAYT 493
+G P +C +C P ++ P C + C NG +C V C CP T
Sbjct: 433 SGDENPDIECADC-PIGFYNDPHDPRSC--KPCPCHNGFSCSVMPETEEVVCNNCPPGVT 489
Query: 494 GILCEKLRCEEAGSCGSDSGQGAP 517
G CE C + G G G+ P
Sbjct: 490 GARCE--LCAD-GYFGDPFGEHGP 510
>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
Length = 1668
Score = 88.2 bits (217), Expect = 2e-17
Identities = 56/153 (36%), Positives = 70/153 (45%), Gaps = 32/153 (20%)
Query: 339 SPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCEL 398
SPG Y C+P C C GHSN+C + ICV+C+HNT G+HCE
Sbjct: 60 SPGYYRDHKGLYTGRCVP-------CNCNGHSNQCQD----GSGICVNCQHNTAGEHCER 108
Query: 399 CRLGYFRNASAQLDDENVCIECYCNPLGSIHDRC---NGSGFCECKTGTTGPKCDECLP- 454
C+ GY+ NA C C C S C G C CK G TG +C+ C P
Sbjct: 109 CQEGYYGNAV-----HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPG 163
Query: 455 --GNSWHYG--CQPNVCDNELLHCQNG--GTCH 481
GN +G CQP C++ NG G+CH
Sbjct: 164 YFGNPQKFGGSCQPCSCNS------NGQLGSCH 190
Score = 63.9 bits (154), Expect = 3e-10
Identities = 49/159 (30%), Positives = 59/159 (37%), Gaps = 26/159 (16%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
C CN H+ C D S + C+HNT G C +C++ Y G GS P C
Sbjct: 78 CNCNGHSNQC-QDGSGICVNCQHNTAGEHCERCQEGYYGNA-VHGSCRACP------CPH 129
Query: 357 SISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENV 416
+ S C G RC SCK G CE C GYF N
Sbjct: 130 TNSFATGCVVNGGDVRC------------SCKAGYTGTQCERCAPGYFGNPQ---KFGGS 174
Query: 417 CIECYCN---PLGSIHDRCNGSGFCECKTGTTGPKCDEC 452
C C CN LGS H E K + +CD+C
Sbjct: 175 CQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
Score = 53.9 bits (128), Expect = 4e-07
Identities = 33/105 (31%), Positives = 45/105 (42%), Gaps = 8/105 (7%)
Query: 399 CRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFC-ECKTGTTGPKCDECLPG-- 455
C GY+R+ C+ C CN G + +GSG C C+ T G C+ C G
Sbjct: 59 CSPGYYRDHKGLYTGR--CVPCNCN--GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYY 114
Query: 456 -NSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEK 499
N+ H C+ C + +VRC C A YTG CE+
Sbjct: 115 GNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCER 159
>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
Length = 1724
Score = 88.2 bits (217), Expect = 2e-17
Identities = 56/153 (36%), Positives = 70/153 (45%), Gaps = 32/153 (20%)
Query: 339 SPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCEL 398
SPG Y C+P C C GHSN+C + ICV+C+HNT G+HCE
Sbjct: 60 SPGYYRDHKGLYTGRCVP-------CNCNGHSNQCQD----GSGICVNCQHNTAGEHCER 108
Query: 399 CRLGYFRNASAQLDDENVCIECYCNPLGSIHDRC---NGSGFCECKTGTTGPKCDECLP- 454
C+ GY+ NA C C C S C G C CK G TG +C+ C P
Sbjct: 109 CQEGYYGNAV-----HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPG 163
Query: 455 --GNSWHYG--CQPNVCDNELLHCQNG--GTCH 481
GN +G CQP C++ NG G+CH
Sbjct: 164 YFGNPQKFGGSCQPCSCNS------NGQLGSCH 190
Score = 63.9 bits (154), Expect = 3e-10
Identities = 49/159 (30%), Positives = 59/159 (37%), Gaps = 26/159 (16%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
C CN H+ C D S + C+HNT G C +C++ Y G GS P C
Sbjct: 78 CNCNGHSNQC-QDGSGICVNCQHNTAGEHCERCQEGYYGNA-VHGSCRACP------CPH 129
Query: 357 SISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENV 416
+ S C G RC SCK G CE C GYF N
Sbjct: 130 TNSFATGCVVNGGDVRC------------SCKAGYTGTQCERCAPGYFGNPQ---KFGGS 174
Query: 417 CIECYCN---PLGSIHDRCNGSGFCECKTGTTGPKCDEC 452
C C CN LGS H E K + +CD+C
Sbjct: 175 CQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
Score = 53.9 bits (128), Expect = 4e-07
Identities = 33/105 (31%), Positives = 45/105 (42%), Gaps = 8/105 (7%)
Query: 399 CRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFC-ECKTGTTGPKCDECLPG-- 455
C GY+R+ C+ C CN G + +GSG C C+ T G C+ C G
Sbjct: 59 CSPGYYRDHKGLYTGR--CVPCNCN--GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYY 114
Query: 456 -NSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEK 499
N+ H C+ C + +VRC C A YTG CE+
Sbjct: 115 GNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCER 159
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 86.7 bits (213), Expect = 5e-17
Identities = 56/189 (29%), Positives = 81/189 (42%), Gaps = 36/189 (19%)
Query: 296 RCKCNLHATVCVYDNSKLTCE-CEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTC 354
RC C+ H+ C + C+ C+H+T GP C +C+ PG Y +GT C
Sbjct: 1158 RCSCHGHSEACEPETG--ACQGCQHHTEGPRCEQCQ---------PGYYGDAQRGTPQDC 1206
Query: 355 IPSISSIGNCECFG-----HSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNAS- 408
C C+G + ++D C +C G+HCE C GY+ N S
Sbjct: 1207 -------QLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQ 1259
Query: 409 ---AQLDDENVC-IECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHY---- 460
Q D + I C C+P GS+ +C+ +G C+CK G C C P + +H
Sbjct: 1260 GQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRP-HHFHLSASN 1318
Query: 461 --GCQPNVC 467
GC P C
Sbjct: 1319 PDGCLPCFC 1327
Score = 74.3 bits (181), Expect = 3e-13
Identities = 59/206 (28%), Positives = 78/206 (37%), Gaps = 42/206 (20%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCS 374
C C GP C C Y P G YL TC C C GHS C
Sbjct: 1126 CSCPPGYRGPSCQDCDTGYTRTP--SGLYL-------GTC-------ERCSCHGHSEACE 1169
Query: 375 YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNP-LGSIHDRC- 432
T C C+H+T G CE C+ GY+ +A + CY +P G C
Sbjct: 1170 ----PETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCF 1225
Query: 433 ---NGSGFCE-CKTGTTGPKCDECLPGNSWHYG----CQPNVCDNEL-----LHCQNGGT 479
+G C+ C G +G C+ C PG +YG QP D+++ +C G+
Sbjct: 1226 LDTDGHPTCDACSPGHSGRHCERCAPG---YYGNPSQGQPCQRDSQVPGPIGCNCDPQGS 1282
Query: 480 ----CHNNVRCLCPAAYTGILCEKLR 501
C +C C A G+ C R
Sbjct: 1283 VSSQCDAAGQCQCKAQVEGLTCSHCR 1308
Score = 70.5 bits (171), Expect = 4e-12
Identities = 56/208 (26%), Positives = 81/208 (38%), Gaps = 30/208 (14%)
Query: 302 HATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSI 361
HAT +S C C +G C C ++ P P YL TC
Sbjct: 718 HATSHGRAHSVEECRCPIGYSGLSCESCDAHFTRVPGGP--YL-------GTC------- 761
Query: 362 GNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNA-SAQLDDENVCIEC 420
C C GH++ C + C++C+HNT G C C+ G+F +A A C
Sbjct: 762 SGCNCNGHASSCDPV----YGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCP 817
Query: 421 YCNPLGSIHDRC----NGSGFCE-CKTGTTGPKCDECLP---GNSWHYGCQPNVCDNELL 472
Y + D C +G C+ C G TG +C+ C P GN G + + E++
Sbjct: 818 YIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIV 877
Query: 473 HC-QNGGTCHNNVRCLCPAAYTGILCEK 499
C + G + C C G LC +
Sbjct: 878 RCDERGSMGTSGEACRCKNNVVGRLCNE 905
Score = 70.5 bits (171), Expect = 4e-12
Identities = 58/196 (29%), Positives = 71/196 (36%), Gaps = 44/196 (22%)
Query: 297 CKCNLHATVC--VYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTC 354
C CN HA+ C VY + C+HNT GP C KCK + G K TA +C
Sbjct: 764 CNCNGHASSCDPVYGHC---LNCQHNTEGPQCNKCKAGFFGDAM---------KATATSC 811
Query: 355 IPSISSIGNCECFGHSNRCS---YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQL 411
P C S R S ++D C +C G+ CE C GY N
Sbjct: 812 RPC-----PCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPG 866
Query: 412 DDENVCIECYCNPLGSIHDRCNGSGF-------CECKTGTTGPKCDECLPGNSWHY---- 460
C P+ RC+ G C CK G C+EC G S+H
Sbjct: 867 GK--------CRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADG-SFHLSTRN 917
Query: 461 --GCQPNVCDNELLHC 474
GC C HC
Sbjct: 918 PDGCLKCFCMGVSRHC 933
Score = 65.9 bits (159), Expect = 9e-11
Identities = 50/164 (30%), Positives = 66/164 (40%), Gaps = 28/164 (17%)
Query: 364 CECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYC- 422
CEC GHS+ C T C C+HN G+ CELC GY+ +A+A ++ C C C
Sbjct: 1563 CECNGHSDLCHP----ETGACSQCQHNAAGEFCELCAPGYYGDATAGTPED--CQPCACP 1616
Query: 423 --NPLGSIHDRCNGSG-----FCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQ 475
NP C G C+ G TG C++C PG + Q C E
Sbjct: 1617 LTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAP 1676
Query: 476 NGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPH 519
H R + P + LRC+ +GS PPH
Sbjct: 1677 LVVEVH-PARSIVPQGGS----HSLRCQVSGS---------PPH 1706
Score = 53.9 bits (128), Expect = 4e-07
Identities = 34/114 (29%), Positives = 47/114 (41%), Gaps = 12/114 (10%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
C+CN H+ +C + + +C+HN G C C +PG Y GT C P
Sbjct: 1563 CECNGHSDLC-HPETGACSQCQHNAAGEFCELC---------APGYYGDATAGTPEDCQP 1612
Query: 357 SISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQ 410
+ N E S C + C +C+ GQ+CE C GY N S Q
Sbjct: 1613 CACPLTNPENM-FSRTCESLG-AGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQ 1664
Score = 43.1 bits (100), Expect = 6e-04
Identities = 45/148 (30%), Positives = 60/148 (40%), Gaps = 28/148 (18%)
Query: 386 SCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCN-GSGFCE-CKTG 443
SC RG C+ C GY R S C C C+ + C +G C+ C+
Sbjct: 1127 SCPPGYRGPSCQDCDTGYTRTPSGLY--LGTCERCSCH---GHSEACEPETGACQGCQHH 1181
Query: 444 TTGPKCDECLPGNSWHYG---------CQPNVCDNELLHCQNGGTC----HNNVRC-LCP 489
T GP+C++C PG +YG CQ C + Q TC + C C
Sbjct: 1182 TEGPRCEQCQPG---YYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACS 1238
Query: 490 AAYTGILCEKLRCEEAGSCGSDSGQGAP 517
++G CE RC G G+ S QG P
Sbjct: 1239 PGHSGRHCE--RC-APGYYGNPS-QGQP 1262
Score = 42.0 bits (97), Expect = 0.001
Identities = 43/156 (27%), Positives = 55/156 (35%), Gaps = 24/156 (15%)
Query: 387 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNG-SGFC-ECKTGT 444
C G C+ C GY R S C C CN D C+ +G C +C+
Sbjct: 1532 CPPGYIGLSCQDCAPGYTRTGSGLYLGH--CELCECN---GHSDLCHPETGACSQCQHNA 1586
Query: 445 TGPKCDECLPGNSWHYG---------CQPNVCDNELLHCQNGGTCHN----NVRCL-CPA 490
G C+ C PG +YG CQP C TC + RC C
Sbjct: 1587 AGEFCELCAPG---YYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEP 1643
Query: 491 AYTGILCEKLRCEEAGSCGSDSGQGAPPHGSPALLL 526
YTG CE+ G+ GQ P L++
Sbjct: 1644 GYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPLVV 1679
Score = 37.0 bits (84), Expect = 0.046
Identities = 30/105 (28%), Positives = 39/105 (37%), Gaps = 22/105 (20%)
Query: 417 CIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQN 476
C + C G HD + S C C G TG +C+ +S C P C +
Sbjct: 3848 CRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCE-----HSQALHCHPEACGPD------ 3896
Query: 477 GGTCHN-----NVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGA 516
TC N C C +G LRCEE + + S GA
Sbjct: 3897 -ATCVNRPDGRGYTCRCHLGRSG-----LRCEEGVTVTTPSLSGA 3935
Score = 31.6 bits (70), Expect = 1.9
Identities = 11/31 (35%), Positives = 16/31 (51%)
Query: 468 DNELLHCQNGGTCHNNVRCLCPAAYTGILCE 498
D + H + G H+ C CP Y+G+ CE
Sbjct: 713 DTTVTHATSHGRAHSVEECRCPIGYSGLSCE 743
Score = 30.0 bits (66), Expect = 5.6
Identities = 23/85 (27%), Positives = 30/85 (35%), Gaps = 2/85 (2%)
Query: 395 HCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLP 454
HC CR +N D E+ C C P G RC S C GP
Sbjct: 3844 HCPTCRDRPCQNGGQCHDSESSSYVCVC-PAGFTGSRCEHSQALHCHPEACGPDATCVNR 3902
Query: 455 GNSWHYGCQPNVCDNELLHCQNGGT 479
+ Y C+ ++ L C+ G T
Sbjct: 3903 PDGRGYTCRCHL-GRSGLRCEEGVT 3926
>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
Length = 639
Score = 84.3 bits (207), Expect = 2e-16
Identities = 53/212 (25%), Positives = 90/212 (42%), Gaps = 43/212 (20%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
C C+ H + + NS C+C+ G C +C+ Y G + N C+P
Sbjct: 291 CDCSPHGALSIPCNSSGKCQCKVGVIGSICDRCQDGYYGF-------------SKNGCLP 337
Query: 357 SISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENV 416
C+C S C + T C++C+ N++G HCE C+ G++++ A +
Sbjct: 338 -------CQCNNRSASCDAL----TGACLNCQENSKGNHCEECKEGFYQSPDATKE---- 382
Query: 417 CIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQN 476
C+ C C+ + S +G C K+ P+CD+C G + G N C+N + +
Sbjct: 383 CLRCPCSAVTS-------TGSCSIKSSELEPECDQCKDG---YIGPNCNKCENGYYNFDS 432
Query: 477 GGTCHNNVRCLCPAAYTGILCEKLRCEEAGSC 508
C +C C + K+ E+G C
Sbjct: 433 --ICR---KCQCHGHVDPVKTPKICKPESGEC 459
Score = 75.5 bits (184), Expect = 1e-13
Identities = 55/184 (29%), Positives = 78/184 (42%), Gaps = 31/184 (16%)
Query: 329 CKKNYQGRPWSPGSYLPIPKGTANTCIPSISS---IGNCECFG--HSNRCSYIDLLNTVI 383
C+ N + + YLP+ + N + + NC G + NRC+ T
Sbjct: 211 CESNLKSK------YLPLTQPVMNLRVSEAVKTEYVCNCSVVGSLNVNRCN-----QTTG 259
Query: 384 CVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTG 443
C+ +G HCE C+ G++ N ++ L C C C+P G++ CN SG C+CK G
Sbjct: 260 QCECRPGYQGLHCETCKEGFYLNYTSGL-----CQPCDCSPHGALSIPCNSSGKCQCKVG 314
Query: 444 TTGPKCDECLPG--NSWHYGCQPNVCDNELLHCQN-GGTCHNNVRCLCPAAYTGILCEKL 500
G CD C G GC P C+N C G C N C G CE+
Sbjct: 315 VIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLN-----CQENSKGNHCEE- 368
Query: 501 RCEE 504
C+E
Sbjct: 369 -CKE 371
Score = 42.7 bits (99), Expect = 8e-04
Identities = 31/115 (26%), Positives = 44/115 (38%), Gaps = 28/115 (24%)
Query: 296 RCKCNLHATV--CVYDNSKLTCECEH---NTTGPDCGKCKKNYQGRPWSPGSYLPIPKGT 350
RC C+ + C +S+L EC+ GP+C KC+ Y
Sbjct: 385 RCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFD------------- 431
Query: 351 ANTCIPSISSIGNCECFGHSN--RCSYIDLLNTVICVSCKHNTRGQHCELCRLGY 403
S C+C GH + + I + C++C HNT G CE C GY
Sbjct: 432 --------SICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.464
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,654,941
Number of Sequences: 37866
Number of extensions: 1351736
Number of successful extensions: 5206
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 105
Number of HSP's successfully gapped in prelim test: 157
Number of HSP's that attempted gapping in prelim test: 2937
Number of HSP's gapped (non-prelim): 1102
length of query: 539
length of database: 18,247,518
effective HSP length: 107
effective length of query: 432
effective length of database: 14,195,856
effective search space: 6132609792
effective search space used: 6132609792
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.