Guide to the Human Genome
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Search of human proteins with 163965366

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|163965366 nascent polypeptide-associated complex alpha
subunit isoform a [Homo sapiens]
         (2078 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|163965366 nascent polypeptide-associated complex alpha subuni...  4167   0.0  
gi|116284392 mucin 2 precursor [Homo sapiens]                         431   e-120
gi|163965362 nascent polypeptide-associated complex alpha subuni...   365   e-100
gi|5031931 nascent polypeptide-associated complex alpha subunit ...   365   e-100
gi|163965364 nascent polypeptide-associated complex alpha subuni...   365   e-100
gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]           330   7e-90
gi|40548328 nascent-polypeptide-associated complex alpha polypep...   329   2e-89
gi|226437579 NAC alpha domain containing [Homo sapiens]               327   1e-88
gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens]    327   1e-88
gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]    319   2e-86
gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens]    319   2e-86
gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens]    317   6e-86
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                  305   4e-82
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                   305   4e-82
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                  300   1e-80
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                  300   1e-80
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...   286   1e-76
gi|91982772 mucin 17 [Homo sapiens]                                   270   8e-72
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     243   2e-63
gi|167736355 mucin 4 isoform a [Homo sapiens]                         242   3e-63
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     239   3e-62
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   238   3e-62
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]            238   6e-62
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   237   1e-61
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   236   2e-61
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   228   6e-59
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   228   6e-59
gi|150170670 piccolo isoform 2 [Homo sapiens]                         221   8e-57
gi|150378539 piccolo isoform 1 [Homo sapiens]                         221   8e-57
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...   211   6e-54

>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 4167 bits (10806), Expect = 0.0
 Identities = 2078/2078 (100%), Positives = 2078/2078 (100%)

Query: 1    MPGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSA 60
            MPGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSA
Sbjct: 1    MPGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSA 60

Query: 61   ANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALAS 120
            ANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALAS
Sbjct: 61   ANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALAS 120

Query: 121  PMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIA 180
            PMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIA
Sbjct: 121  PMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIA 180

Query: 181  PSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLA 240
            PSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLA
Sbjct: 181  PSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLA 240

Query: 241  IASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPD 300
            IASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPD
Sbjct: 241  IASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPD 300

Query: 301  FPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPL 360
            FPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPL
Sbjct: 301  FPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPL 360

Query: 361  PSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPN 420
            PSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPN
Sbjct: 361  PSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPN 420

Query: 421  ATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSP 480
            ATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSP
Sbjct: 421  ATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSP 480

Query: 481  AALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLE 540
            AALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLE
Sbjct: 481  AALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLE 540

Query: 541  GAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLP 600
            GAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLP
Sbjct: 541  GAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLP 600

Query: 601  IGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAP 660
            IGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAP
Sbjct: 601  IGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAP 660

Query: 661  TTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAP 720
            TTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAP
Sbjct: 661  TTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAP 720

Query: 721  LATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASAT 780
            LATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASAT
Sbjct: 721  LATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASAT 780

Query: 781  ASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS 840
            ASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS
Sbjct: 781  ASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS 840

Query: 841  LSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP 900
            LSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP
Sbjct: 841  LSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP 900

Query: 901  ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK 960
            ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK
Sbjct: 901  ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK 960

Query: 961  WAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK 1020
            WAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK
Sbjct: 961  WAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK 1020

Query: 1021 GSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP 1080
            GSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP
Sbjct: 1021 GSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP 1080

Query: 1081 TPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL 1140
            TPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL
Sbjct: 1081 TPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL 1140

Query: 1141 ATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1200
            ATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA
Sbjct: 1141 ATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1200

Query: 1201 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPP 1260
            TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPP
Sbjct: 1201 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPP 1260

Query: 1261 KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSP 1320
            KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSP
Sbjct: 1261 KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSP 1320

Query: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380
            KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG
Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380

Query: 1381 GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTP 1440
            GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTP
Sbjct: 1381 GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTP 1440

Query: 1441 VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM 1500
            VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM
Sbjct: 1441 VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM 1500

Query: 1501 GAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK 1560
            GAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK
Sbjct: 1501 GAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK 1560

Query: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620
            TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT
Sbjct: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620

Query: 1621 PPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTA 1680
            PPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTA
Sbjct: 1621 PPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTA 1680

Query: 1681 LKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLP 1740
            LKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLP
Sbjct: 1681 LKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLP 1740

Query: 1741 VQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSL 1800
            VQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSL
Sbjct: 1741 VQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSL 1800

Query: 1801 PLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLV 1860
            PLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLV
Sbjct: 1801 PLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLV 1860

Query: 1861 NMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAA 1920
            NMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAA
Sbjct: 1861 NMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAA 1920

Query: 1921 EIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPAS 1980
            EIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPAS
Sbjct: 1921 EIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPAS 1980

Query: 1981 DTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVE 2040
            DTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVE
Sbjct: 1981 DTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVE 2040

Query: 2041 VKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 2078
            VKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM
Sbjct: 2041 VKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 2078


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score =  431 bits (1108), Expect = e-120
 Identities = 475/2009 (23%), Positives = 688/2009 (34%), Gaps = 184/2009 (9%)

Query: 2    PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTL---PPPCSPAPQQCPL 58
            P   T T P T    P     T   P ++     +    P PT    PP  +P+P     
Sbjct: 1425 PTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTP 1484

Query: 59   SAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAP------------------ 100
            S     +  P P+T  S P   P    +S T LP  T P  P                  
Sbjct: 1485 SPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTT 1544

Query: 101  ---------TFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKS- 150
                     T LP    P   P       P   P+   T + S P       P +   S 
Sbjct: 1545 TPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSP 1604

Query: 151  -----SAFPPNLLTSPPSVA-VAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNP--KGT 202
                 +  PP    SPP+   +    S  TL     PS P T     P    P+P    T
Sbjct: 1605 PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT 1664

Query: 203  PSPPCIVSTVPYHCVTPMASIQS--GVASLPQTTPTTTLAIASPQVKDTTISSVLISPQN 260
            PSPP   +T P    TP + I +     +   TTP+ T   +SP    TT SS       
Sbjct: 1665 PSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPP 1724

Query: 261  PGSLSLKGPVSPPAALSLSTQSL-PVVTSSQKTAGP----NTPPDF-PISLGSHLAPLHQ 314
            P +++   P + P+  + +  +L P  TSS  T  P     TPP F P S  +   P   
Sbjct: 1725 PTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTP--- 1781

Query: 315  SSFGSVQLLGQTGPSALSDPTVKTISVDHSSTG--------ASYPSQRSVIP--PLPSRN 364
                 V L   TG      P       D    G        A+   + ++ P  P+    
Sbjct: 1782 ----CVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLG 1837

Query: 365  EVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYH 424
            + V   V+   ++  + D+ P  +  +    +  +NV     ++  T++   ++ N T  
Sbjct: 1838 QTVVCDVSV-GLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPT-- 1894

Query: 425  YPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALV 484
                     + + TT  V   P        TT  + T  +   +  P     PT+     
Sbjct: 1895 -----PPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 1949

Query: 485  MAPVAPKEPSTQVATTLRIPVS-----PPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASL 539
               V P    T   T    P++      P P P   +  P++  +   T       P   
Sbjct: 1950 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGT 2008

Query: 540  EGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSP-------EIPLSPEATLAK 592
            +    +P     TT   PT  P     P  +P   +T+ +P       + P +   T   
Sbjct: 2009 QTPTTTPITT--TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2066

Query: 593  KSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLES 652
                 P P G    + T+P+   ++ +   T +     +  P+  ++ +TPT        
Sbjct: 2067 TVTPTPTPTGTQTPT-TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-------- 2117

Query: 653  ADPAGV-APTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASE---NC 708
              P G   PTT   T+T T T +P   GT +  P   P+   T  T    PT ++     
Sbjct: 2118 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTT 2175

Query: 709  PVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPK 768
            P+  +   T  P  T    P       + ++ P  TP GT+       T    P+ ++  
Sbjct: 2176 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-------TPTTTPITTTTT 2228

Query: 769  ECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGP-DTPIGNLSSP 827
              PT     + T ++    T    +P+P        T  P T   +  P  TP G  +  
Sbjct: 2229 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2288

Query: 828  VSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPT 887
             +P+  +     + +  G++ +P TT   T  +    PTP+     +   +T     TPT
Sbjct: 2289 TTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2347

Query: 888  PSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATP 947
            P+      P   P T      P  + T +             +  +P+P G  TP     
Sbjct: 2348 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2407

Query: 948  PSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007
             +      TP+P    TP      +      TP+P G  TP      +      TP+P G
Sbjct: 2408 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2467

Query: 1008 APTPPAVTPPSPKGSPAATPFPKGASTP-----PAATPPSPKGSPAATPLPKGAPTTPAA 1062
              T P  TP +   +   TP P G  TP        T  +P  +P  T  P   P T   
Sbjct: 2468 TQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2526

Query: 1063 TL-PSP-KGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120
            T+ P+P   G  TP+     T    TP     G  TP+          TP     G  TP
Sbjct: 2527 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2586

Query: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180
                  TT   TP     G  TP      TT   TP     G  TP      TT   TP 
Sbjct: 2587 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2646

Query: 1181 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA 1240
                G  TP+     TT   TP     G  TP+     TT   TP     G  TP+    
Sbjct: 2647 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2706

Query: 1241 PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP-PSPKG 1299
             TT   TP     G  TP      T    TP     G  TP          VTP P+P G
Sbjct: 2707 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2766

Query: 1300 --GPATSPPKGAPTPPAATP-PSPKGSPGTPPPKGAPTPPAVTP-PSPKGT---PTLPAT 1352
               P T+P     T    TP P+P G+  TP      T   VTP P+P GT    T P T
Sbjct: 2767 TQTPTTTP---ITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2822

Query: 1353 TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP 1412
            T ++     TP+  + PT    T +    P  TP   +     P       +P   P   
Sbjct: 2823 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2882

Query: 1413 KKAPATPVTREGAATPS---KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPA 1469
            +    TP+T     TP+    G  T P  TP++       +    G  TP++    T   
Sbjct: 2883 QTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2941

Query: 1470 VTP-PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPI- 1527
            VTP P+P     P     +++    P TP P G  T        P   P T ++   P  
Sbjct: 2942 VTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT--------PTTTPITTTTTVTPTP 2992

Query: 1528 APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPA-TPSSKEA-SSPPAV 1585
             PT T     TP T        P      +P  TP   T    P  TP+  +  ++ P  
Sbjct: 2993 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3052

Query: 1586 TPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPS 1645
            T +T    P+P     P   T+P        P  TP   +    TP    T  +P  TP+
Sbjct: 3053 TTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3110

Query: 1646 SLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP------APESTPIIT-- 1697
              +   T+P + T  +  T        P     T    V   P       P +TPI T  
Sbjct: 3111 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3170

Query: 1698 ----APTRKGPQTKKSS--ATSPPICPDPSAKNGSKGP-------LSTVAPAPLLPVQKD 1744
                 PT  G QT  ++   T+  + P P+   G++ P        +TV P P     + 
Sbjct: 3171 TVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3229

Query: 1745 SSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAP 1804
             + T      + +P       ++  +TP+T      V P P         + P++     
Sbjct: 3230 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTTV 3287

Query: 1805 SPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPT 1864
            +P PT  P     P++  +   +   P  P       P   P      +   + +   PT
Sbjct: 3288 TPTPT--PTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTP------ITTTTTVTPTPT 3338

Query: 1865 PKSAGIPVPTP-SAKQPVTKNNKGSGTES 1892
            P     P  TP +    VT     +GT++
Sbjct: 3339 PTGTQTPTTTPITTTTTVTPTPTPTGTQT 3367



 Score =  431 bits (1107), Expect = e-120
 Identities = 474/2029 (23%), Positives = 696/2029 (34%), Gaps = 223/2029 (10%)

Query: 6    TETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTL------------PPPCSPAP 53
            T   P T    P P + T + P ++    T     P PT             PP  +P+P
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456

Query: 54   QQCPLSAANQASPFPSPS---TIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPP 110
               P+S      P  +PS   T  S P   P P +++ T  P  T P  PT  P  I PP
Sbjct: 1457 ---PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP--ITPP 1511

Query: 111  ISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVA-VAES 169
             S   L        PT   +P ++               ++  PP    SPP+   +   
Sbjct: 1512 ASTTTL-------PPTTTPSPPTTT--------------TTTPPPTTTPSPPTTTPITPP 1550

Query: 170  GSVITLSAPIAPSEPKTNLNKVPSEVVPNP--KGTPSPPCIVSTVPYHCVTPMASIQSGV 227
             S  TL     PS P T     P    P+P    TPSPP I +T P    TP     +  
Sbjct: 1551 TSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTT 1610

Query: 228  ASLPQTTPT-TTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVV 286
               P TTP+  T    +P    TT+         P + +   P + P+  + +T S P+ 
Sbjct: 1611 TPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPIT 1670

Query: 287  TSSQKTAGPNTPPDFPIS---------------LGSHLAPLHQSSFGSVQLLGQTGPSAL 331
            T++  T  P T P  PI+                 +  +P+  ++  S        P+ +
Sbjct: 1671 TTT--TPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTM 1728

Query: 332  SDPTVKTISVDHSSTGASYPSQRSVIP----PLPSRNEVVPATVAAFPVVAPSV------ 381
            + P+  T     ++T  + P   +  P    PLP    + P T + F    P+       
Sbjct: 1729 TTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPP--SITPPTFSPFSTTTPTTPCVPLC 1786

Query: 382  ---------------DKGPSTISSITCSPSGSLNVATSFSLSP---------------TT 411
                             G + +    C P  + N++   ++ P               + 
Sbjct: 1787 NWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSV 1846

Query: 412  SLILKS---SPNATYHYPLVAQMPVS----SVGTTPLVVTNPCTIAAAPTTTFEVATCVS 464
             LI K+    P             ++       T P  +T   T    P TT  + T  +
Sbjct: 1847 GLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTT 1906

Query: 465  PPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVS-----PPLPDPEDLKNLP 519
               +  P     PT+        V P    T   T    P++      P P P   +  P
Sbjct: 1907 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-P 1965

Query: 520  SSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSS 579
            ++  +   T       P   +    +P     TT   PT  P     P  +P   +T+ +
Sbjct: 1966 TTTPITTTTTVTPTPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQTPTTTPITTTTTVT 2023

Query: 580  P-------EIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSA 632
            P       + P +   T        P P G    + T+P+   ++ +   T +     + 
Sbjct: 2024 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTPTPTPTGTQTPTT 2082

Query: 633  GPLLKSSLITPTVAAFPLESADPAGV-APTTAKGTSTYTTTASPFLEGTVSLAPKNHPVK 691
             P+  ++ +TPT          P G   PTT   T+T T T +P   GT +  P   P+ 
Sbjct: 2083 TPITTTTTVTPT--------PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPIT 2132

Query: 692  EGTLTTLPLVPTASE---NCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGT 748
              T  T    PT ++     P+  +   T  P  T    P       + ++ P  TP GT
Sbjct: 2133 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2192

Query: 749  KKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRP 808
            +       T    P+ ++    PT     + T ++    T    +P+P        T  P
Sbjct: 2193 Q-------TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2245

Query: 809  PTKKGSAGP-DTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTP 867
             T   +  P  TP G  +   +P+  +     + +  G++ +P TT   T  +    PTP
Sbjct: 2246 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTP 2304

Query: 868  SAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAP 927
            +     +   +T     TPTP+      P   P T      P  + T +           
Sbjct: 2305 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2364

Query: 928  KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPT 987
              +  +P+P G  TP      +      TP+P    TP      +      TP+P G  T
Sbjct: 2365 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2424

Query: 988  PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP-----PAATPPS 1042
            P      +      TP+P G  T P  TP +   +   TP P G  TP        T  +
Sbjct: 2425 PTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2483

Query: 1043 PKGSPAATPLPKGAPTTPAATL-PSP-KGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100
            P  +P  T  P   P T   T+ P+P   G  TP+     T    TP     G  TP+  
Sbjct: 2484 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2543

Query: 1101 GAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1160
                    TP     G  TP      TT   TP     G  TP      TT   TP    
Sbjct: 2544 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2603

Query: 1161 GGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1220
             G  TP      TT   TP     G  TP+     TT   TP     G  TP+     TT
Sbjct: 2604 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2663

Query: 1221 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLAT 1280
               TP     G  TP+     TT   TP     G  TP      T    TP     G  T
Sbjct: 2664 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2723

Query: 1281 PPHKGAPNPAVVTP-PSPKG--GPATSPPKGAPTPPAATP-PSPKGSPGTPPPKGAPTPP 1336
            P          VTP P+P G   P T+P     T    TP P+P G+  TP      T  
Sbjct: 2724 PTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQ-TPTTTPITTTT 2779

Query: 1337 AVTP-PSPKGT---PTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392
             VTP P+P GT    T P TT ++     TP+  + PT    T +    P  TP   +  
Sbjct: 2780 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2839

Query: 1393 PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPS---KGDLTPPAVTPVSLKKAPAT 1449
               P       +P   P   +    TP+T     TP+    G  T P  TP++       
Sbjct: 2840 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTP 2898

Query: 1450 SAPKGGPATPSSKGDPTLPAVTP-PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV 1508
            +    G  TP++    T   VTP P+P     P     +++    P TP P G  T    
Sbjct: 2899 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT---- 2953

Query: 1509 IPSSPKEVPATPSSRRDPI-APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTP 1567
                P   P T ++   P   PT T     TP T        P      +P  TP   T 
Sbjct: 2954 ----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3009

Query: 1568 KEAPA-TPSSKEA-SSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPE 1625
               P  TP+  +  ++ P  T +T    P+P     P   T+P        P  TP   +
Sbjct: 3010 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTPTGTQ 3067

Query: 1626 KGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVL 1685
                TP    T  +P  TP+  +   T+P + T  +  T        P     T    V 
Sbjct: 3068 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3127

Query: 1686 VAP------APESTPIIT------APTRKGPQTKKSS--ATSPPICPDPSAKNGSKGP-- 1729
              P       P +TPI T       PT  G QT  ++   T+  + P P+   G++ P  
Sbjct: 3128 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQTPTT 3186

Query: 1730 -----LSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPK 1784
                  +TV P P     +  + T      + +P       ++  +TP+T      V P 
Sbjct: 3187 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT--TVTPT 3244

Query: 1785 PESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLI 1844
            P         + P++     +P PT  P     P++  +   +   P  P       P  
Sbjct: 3245 PTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTT 3301

Query: 1845 PPEPISGGVPFQSVLVNMPTPKSAGIPVPTP-SAKQPVTKNNKGSGTES 1892
             P      +   + +   PTP     P  TP +    VT     +GT++
Sbjct: 3302 TP------ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3344



 Score =  417 bits (1073), Expect = e-116
 Identities = 465/1966 (23%), Positives = 687/1966 (34%), Gaps = 198/1966 (10%)

Query: 6    TETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQAS 65
            T  +  T    P P       P ++ ++ T  +    PT  P  +  P   P++     +
Sbjct: 2450 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT---PTPTPTGTQTPTTTPITTTTTVT 2506

Query: 66   PFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAP 125
            P P+P T   TP   P   +++ T  P  T  + PT  P      ++P           P
Sbjct: 2507 PTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--------TP 2557

Query: 126  TLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPK 185
            T   TP+++       + P          P    +P +  +  + +V     P     P 
Sbjct: 2558 TGTQTPTTTPITTTTTVTPTPT-------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2610

Query: 186  TNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVAS-LPQTTPTTTLAIASP 244
            T      + V P P  TP+     +T P    T +    +   +  P TTP TT    +P
Sbjct: 2611 TTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2668

Query: 245  -------QVKDTT-ISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPN 296
                   Q   TT I++       P     + P + P   + +    P  T +Q      
Sbjct: 2669 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ------ 2722

Query: 297  TPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSV 356
            TP   PI+  + + P    +       G   P+     T  T++   + TG   P+   +
Sbjct: 2723 TPTTTPITTTTTVTPTPTPT-------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2775

Query: 357  IP-------PLPSRNEV-----VPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATS 404
                     P P+  +      +  T    P   P+  + P+T + IT + + +     +
Sbjct: 2776 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPT 2834

Query: 405  FSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPT-----TTFEV 459
             + +PTT+ I  ++       P   Q P     TTP+  T   T    PT     TT  +
Sbjct: 2835 GTQTPTTTPITTTTTVTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPI 2890

Query: 460  ATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSP-----PLPDPED 514
             T  +   +  P     PT+        V P    T   T    P++      P P P  
Sbjct: 2891 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2950

Query: 515  LKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQ 574
             +  P++  +   T       P   +    +P     TT   PT  P     P  +P   
Sbjct: 2951 TQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQTPTTTPITT 3007

Query: 575  STSSSP-------EIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYA 627
            +T+ +P       + P +   T        P P G    + T+P+   ++ +   T +  
Sbjct: 3008 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTPTPTPTGT 3066

Query: 628  GPDSAGPLLKSSLITPTVAAFPLESADPAGV-APTTAKGTSTYTTTASPFLEGTVSLAPK 686
               +  P+  ++ +TPT          P G   PTT   T+T T T +P   GT +  P 
Sbjct: 3067 QTPTTTPITTTTTVTPTPT--------PTGTQTPTTTPITTTTTVTPTPTPTGTQT--PT 3116

Query: 687  NHPVKEGTLTTLPLVPTASEN---CPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAG 743
              P+   T  T    PT ++     P+  +   T  P  T    P       + ++ P  
Sbjct: 3117 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3176

Query: 744  TPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSP 803
            TP GT+       T    P+ ++    PT     + T ++    T    +P+P       
Sbjct: 3177 TPTGTQ-------TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3229

Query: 804  QTKRPPTKKGSAGPD-TPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPK 862
             T  P T   +  P  TP G  +   +P+  +     + +  G++ +P TT   T  +  
Sbjct: 3230 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVT 3288

Query: 863  GAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKAR 922
              PTP+     +   +T     TPTP+      P   P T      P  + T +      
Sbjct: 3289 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3348

Query: 923  ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP 982
                   +  +P+P G  TP      +      TP+P    TP      +      TP+P
Sbjct: 3349 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3408

Query: 983  KGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAA---- 1038
             G  TP      +      TP+P G  TP   TP +   +   TP P G  TP       
Sbjct: 3409 TGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITT 3467

Query: 1039 -TPPSPKGSPAATPLPKGAPTTPAATL---PSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094
             T  +P  +P  T  P   P T   T+   P+P G   TP+     T    TP     G 
Sbjct: 3468 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-TQTPTTTPITTTTTVTPTPTPTGT 3526

Query: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1154
             TP+          TP     G  TP      TT   TP     G  TP      TT   
Sbjct: 3527 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3586

Query: 1155 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1214
            TP     G  TP      TT   TP     G  TP+     TT   TP     G  TP+ 
Sbjct: 3587 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3646

Query: 1215 KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSL 1274
                TT   TP     G  TP+     TT   TP     G  TP      T    TP   
Sbjct: 3647 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3706

Query: 1275 KGGLATPPHKGAPNPAVVTP-PSPKGG--PATSPPKGAPTPPAATP-PSPKGSPGTPPPK 1330
              G  TP          VTP P+P G   P T+P     T    TP P+P G+  TP   
Sbjct: 3707 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQ-TPTTT 3762

Query: 1331 GAPTPPAVTP-PSPKGTPTLPATTP---SSKGGPT-TPSSKEGPTPPAATPSHKGGPAMT 1385
               T   VTP P+P GT T P TTP   ++   PT TP+  + PT    T +    P  T
Sbjct: 3763 PITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3821

Query: 1386 PPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTP-----PAVTP 1440
            P   +     P       +P   P   +    TP+T     TP+    TP     P  TP
Sbjct: 3822 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTP 3878

Query: 1441 VSLKKAPATSAPKGGPATPSSKGDPTLPAVTP-PSPKEPPAPKQVATSSSPKKAPATPAP 1499
            ++       +    G  TP++    T   VTP P+P     P     +++    P TP P
Sbjct: 3879 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTP 3937

Query: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDPI-APTATLLSKKTPATLAPKEALIPPAMTVPSP 1558
             G  T        P   P T ++   P   PT T     TP T        P      +P
Sbjct: 3938 TGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3989

Query: 1559 KKTPAIPTPKEAPA-TPSSKEA-SSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP 1616
              TP   T    P  TP+  +  ++ P  T +T    P+P     P   T+P        
Sbjct: 3990 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVT 4047

Query: 1617 PAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKK 1676
            P  TP   +    TP    T  +P  TP+  +   T+P + T  +  T        P   
Sbjct: 4048 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4107

Query: 1677 GPTALKEVLVAPAPE------STPIITA------PTRKGPQTKKSS--ATSPPICPDPSA 1722
              T    V   P P       +TPI T       PT  G QT  ++   T+  + P P+ 
Sbjct: 4108 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4167

Query: 1723 KNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVL 1782
              G++ P +T       P+   ++ T      + +P G    P +  ST    A      
Sbjct: 4168 -TGTQTPTTT-------PITTTTTVTP-----TPTPTGTQTGPPTHTSTA-PIAELTTSN 4213

Query: 1783 PKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLP 1842
            P PES++   + S    L  + + + TLPP  +   ++P      PS P AP        
Sbjct: 4214 PPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAP------PSTPTAPTTTSGGHT 4267

Query: 1843 LIPPEPIS---GGVPFQSVLV---NMPTPK-------SAGIPVPTP 1875
            L PP   +    G P +       + PTP        SA  P PTP
Sbjct: 4268 LSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTP 4313



 Score =  416 bits (1069), Expect = e-115
 Identities = 461/1942 (23%), Positives = 665/1942 (34%), Gaps = 195/1942 (10%)

Query: 66   PFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAP 125
            P     T  S P   P P  +S T LP  T P  PT       P  +P+     +    P
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPP 1450

Query: 126  TLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAP-IAPSEP 184
            T   +P  S           S   ++  PP    SPP+          T S P   P  P
Sbjct: 1451 TTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP 1510

Query: 185  KTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASP 244
              +   +P      P  TPSPP   +T P    TP         S P TTP T      P
Sbjct: 1511 PASTTTLP------PTTTPSPPTTTTTTPPPTTTP---------SPPTTTPIT------P 1549

Query: 245  QVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPIS 304
                TT+         P + +   P + P+  + +T S P +T++  T  P T P  P +
Sbjct: 1550 PTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTT--TPPPTTTPSPPTT 1607

Query: 305  LGSHLAPLHQSSFGSVQLL------GQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIP 358
              +   P    S  +   +          P+    P   T +    +T  S P+  +  P
Sbjct: 1608 TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP 1667

Query: 359  PLPSRNEVVPATVAAFPV-VAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKS 417
            P+ +     P T  + P+   PS      T  S T +PS  +   T+ S + T      S
Sbjct: 1668 PITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTT-----PS 1722

Query: 418  SPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEP 477
             P  T   P     P      T  + T P T  ++P TT  +   ++PP  S P S   P
Sbjct: 1723 PPPTTMTTPSPTTTPSP---PTTTMTTLPPTTTSSPLTTTPLPPSITPPTFS-PFSTTTP 1778

Query: 478  TSPAALV--------------------------------------MAPVAPKEPSTQVAT 499
            T+P   +                                       A + P  P  Q+  
Sbjct: 1779 TTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQ 1838

Query: 500  TLRIPVSPPL----PDPEDLKNLPSSVLVKFP---------TQKDLQTVPASLEGAPFSP 546
            T+   VS  L     D +    +P +  + +          TQ    T   +    P + 
Sbjct: 1839 TVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTT 1898

Query: 547  AQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSP-------EIPLSPEATLAKKSLGEPL 599
                 TT   PT  P     P  +P   +T+ +P       + P +   T        P 
Sbjct: 1899 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1958

Query: 600  PIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGV- 658
            P G    + T+P+   ++ +   T +     +  P+  ++ +TPT          P G  
Sbjct: 1959 PTGTQTPT-TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--------PTPTGTQ 2009

Query: 659  APTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASE---NCPVAPSPQ 715
             PTT   T+T T T +P   GT +  P   P+   T  T    PT ++     P+  +  
Sbjct: 2010 TPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2067

Query: 716  NTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDS 775
             T  P  T    P       + ++ P  TP GT+       T    P+ ++    PT   
Sbjct: 2068 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-------TPTTTPITTTTTVTPTPTP 2120

Query: 776  GASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGP-DTPIGNLSSPVSPVEAS 834
              + T ++    T    +P+P        T  P T   +  P  TP G  +   +P+  +
Sbjct: 2121 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2180

Query: 835  FLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLP 894
                 + +  G++ +P TT   T  +    PTP+     +   +T     TPTP+     
Sbjct: 2181 TTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2239

Query: 895  FPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGP 954
             P   P T      P  + T +             +  +P+P G  TP      +     
Sbjct: 2240 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2299

Query: 955  ATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAV 1014
             TP+P    TP      +      TP+P G  TP      +      TP+P G  T P  
Sbjct: 2300 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTT 2358

Query: 1015 TPPSPKGSPAATPFPKGASTP-----PAATPPSPKGSPAATPLPKGAPTTPAATL-PSP- 1067
            TP +   +   TP P G  TP        T  +P  +P  T  P   P T   T+ P+P 
Sbjct: 2359 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2418

Query: 1068 KGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPT 1127
              G  TP+     T    TP     G  TP+          TP     G  TP      T
Sbjct: 2419 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2478

Query: 1128 TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1187
            T   TP     G  TP      TT   TP     G  TP      TT   TP     G  
Sbjct: 2479 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2538

Query: 1188 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1247
            TP+     TT   TP     G  TP+     TT   TP     G  TP+     TT   T
Sbjct: 2539 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2598

Query: 1248 PPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP-PSPKG--GPATS 1304
            P     G  TP      T    TP     G  TP          VTP P+P G   P T+
Sbjct: 2599 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2658

Query: 1305 PPKGAPTPPAATP-PSPKGSPGTPPPKGAPTPPAVTP-PSPKGT---PTLPATTPSSKGG 1359
            P     T    TP P+P G+  TP      T   VTP P+P GT    T P TT ++   
Sbjct: 2659 P---ITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2714

Query: 1360 PTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATP 1419
              TP+  + PT    T +    P  TP   +     P       +P   P   +    TP
Sbjct: 2715 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2774

Query: 1420 VTREGAATPS---KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP-PSP 1475
            +T     TP+    G  T P  TP++       +    G  TP++    T   VTP P+P
Sbjct: 2775 ITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2833

Query: 1476 KEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPI-APTATLL 1534
                 P     +++    P TP P G  T        P   P T ++   P   PT T  
Sbjct: 2834 TGTQTPTTTPITTTTTVTP-TPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2884

Query: 1535 SKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPA-TPSSKEA-SSPPAVTPSTYKG 1592
               TP T        P      +P  TP   T    P  TP+  +  ++ P  T +T   
Sbjct: 2885 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2944

Query: 1593 APSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPT 1652
             P+P     P   T+P        P  TP   +    TP    T  +P  TP+  +   T
Sbjct: 2945 TPTPTGTQTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3002

Query: 1653 SPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP------APESTPIIT------APT 1700
            +P + T  +  T        P     T    V   P       P +TPI T       PT
Sbjct: 3003 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3062

Query: 1701 RKGPQTKKSS--ATSPPICPDPSAKNGSKGP-------LSTVAPAPLLPVQKDSSKTAKG 1751
              G QT  ++   T+  + P P+   G++ P        +TV P P     +  + T   
Sbjct: 3063 PTGTQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3121

Query: 1752 KDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLP 1811
               + +P       ++  +TP+T      V P P         + P++     +P PT  
Sbjct: 3122 TTTTVTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTTVTPTPT-- 3177

Query: 1812 PKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIP 1871
            P     P++  +   +   P  P       P   P      +   + +   PTP     P
Sbjct: 3178 PTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTP------ITTTTTVTPTPTPTGTQTP 3230

Query: 1872 VPTP-SAKQPVTKNNKGSGTES 1892
              TP +    VT     +GT++
Sbjct: 3231 TTTPITTTTTVTPTPTPTGTQT 3252



 Score =  401 bits (1031), Expect = e-111
 Identities = 442/1886 (23%), Positives = 652/1886 (34%), Gaps = 177/1886 (9%)

Query: 6    TETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQAS 65
            T  +  T    P P       P ++ ++ T  +    PT  P  +  P   P++     +
Sbjct: 2519 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT---PTPTPTGTQTPTTTPITTTTTVT 2575

Query: 66   PFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAP 125
            P P+P T   TP   P   +++ T  P  T  + PT  P      ++P           P
Sbjct: 2576 PTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--------TP 2626

Query: 126  TLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPK 185
            T   TP+++       + P          P    +P +  +  + +V     P     P 
Sbjct: 2627 TGTQTPTTTPITTTTTVTPTPT-------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2679

Query: 186  TNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVAS-LPQTTPTTTLAIASP 244
            T      + V P P  TP+     +T P    T +    +   +  P TTP TT    +P
Sbjct: 2680 TTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2737

Query: 245  -------QVKDTT-ISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPN 296
                   Q   TT I++       P     + P + P   + +    P  T +Q      
Sbjct: 2738 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ------ 2791

Query: 297  TPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSV 356
            TP   PI+  + + P    +       G   P+     T  T++   + TG   P+   +
Sbjct: 2792 TPTTTPITTTTTVTPTPTPT-------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2844

Query: 357  IP-------PLPSRNEV-----VPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATS 404
                     P P+  +      +  T    P   P+  + P+T + IT + + +     +
Sbjct: 2845 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPT 2903

Query: 405  FSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPT-----TTFEV 459
             + +PTT+ I  ++       P   Q P     TTP+  T   T    PT     TT  +
Sbjct: 2904 GTQTPTTTPITTTTTVTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPI 2959

Query: 460  ATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSP-----PLPDPED 514
             T  +   +  P     PT+        V P    T   T    P++      P P P  
Sbjct: 2960 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3019

Query: 515  LKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQ 574
             +  P++  +   T       P   +    +P     TT   PT  P     P  +P   
Sbjct: 3020 TQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQTPTTTPITT 3076

Query: 575  STSSSP-------EIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYA 627
            +T+ +P       + P +   T        P P G    + T+P+   ++ +   T +  
Sbjct: 3077 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTPTPTPTGT 3135

Query: 628  GPDSAGPLLKSSLITPTVAAFPLESADPAGV-APTTAKGTSTYTTTASPFLEGTVSLAPK 686
               +  P+  ++ +TPT          P G   PTT   T+T T T +P   GT +  P 
Sbjct: 3136 QTPTTTPITTTTTVTPTPT--------PTGTQTPTTTPITTTTTVTPTPTPTGTQT--PT 3185

Query: 687  NHPVKEGTLTTLPLVPTASEN---CPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAG 743
              P+   T  T    PT ++     P+  +   T  P  T    P       + ++ P  
Sbjct: 3186 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3245

Query: 744  TPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSP 803
            TP GT+       T    P+ ++    PT     + T ++    T    +P+P       
Sbjct: 3246 TPTGTQ-------TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3298

Query: 804  QTKRPPTKKGSAGPD-TPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPK 862
             T  P T   +  P  TP G  +   +P+  +     + +  G++ +P TT   T  +  
Sbjct: 3299 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVT 3357

Query: 863  GAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKAR 922
              PTP+     +   +T     TPTP+      P   P T      P  + T +      
Sbjct: 3358 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3417

Query: 923  ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP 982
                   +  +P+P G  TP      +      TP+P    TP      +      TP+P
Sbjct: 3418 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3477

Query: 983  KGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAA---- 1038
             G  TP      +      TP+P G  TP   TP +   +   TP P G  TP       
Sbjct: 3478 TGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITT 3536

Query: 1039 -TPPSPKGSPAATPLPKGAPTTPAATL---PSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094
             T  +P  +P  T  P   P T   T+   P+P G   TP+     T    TP     G 
Sbjct: 3537 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-TQTPTTTPITTTTTVTPTPTPTGT 3595

Query: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1154
             TP+          TP     G  TP      TT   TP     G  TP      TT   
Sbjct: 3596 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3655

Query: 1155 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1214
            TP     G  TP      TT   TP     G  TP+     TT   TP     G  TP+ 
Sbjct: 3656 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3715

Query: 1215 KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSL 1274
                TT   TP     G  TP+     TT   TP     G  TP      T    TP   
Sbjct: 3716 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3775

Query: 1275 KGGLATPPHKGAPNPAVVTP-PSPKGG--PATSPPKGAPTPPAATP-PSPKGSPGTPPPK 1330
              G  TP          VTP P+P G   P T+P     T    TP P+P G+  TP   
Sbjct: 3776 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQ-TPTTT 3831

Query: 1331 GAPTPPAVTP-PSPKGTPTLPATTP---SSKGGPT-TPSSKEGPTPPAATPSHKGGPAMT 1385
               T   VTP P+P GT T P TTP   ++   PT TP+  + PT    T +    P  T
Sbjct: 3832 PITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3890

Query: 1386 PPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTP-----PAVTP 1440
            P   +     P       +P   P   +    TP+T     TP+    TP     P  TP
Sbjct: 3891 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTP 3947

Query: 1441 VSLKKAPATSAPKGGPATPSSKGDPTLPAVTP-PSPKEPPAPKQVATSSSPKKAPATPAP 1499
            ++       +    G  TP++    T   VTP P+P     P     +++    P TP P
Sbjct: 3948 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTP 4006

Query: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDPI-APTATLLSKKTPATLAPKEALIPPAMTVPSP 1558
             G  T        P   P T ++   P   PT T     TP T        P      +P
Sbjct: 4007 TGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4058

Query: 1559 KKTPAIPTPKEAPA-TPSSKEASSPPAVTP--STYKGAPSPKELLIPPAVTSPSPKEAPT 1615
              TP   T    P  TP+  +    P  TP  +T    P+P         T+P       
Sbjct: 4059 TTTPITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 4115

Query: 1616 PPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAK 1675
             P  TP   +    TP    T  +P  TP+  +   T+P + T  +  T        P  
Sbjct: 4116 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4175

Query: 1676 KGPTALKEVLVAPAPESTPIITAP---TRKGPQTKKSSATSPPICPDPSAKNGSKGP--- 1729
               T    V   P P  T   T P   T   P  + +++  PP    P     +  P   
Sbjct: 4176 TPITTTTTVTPTPTPTGTQ--TGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTE 4233

Query: 1730 ----LSTVAPA--------PLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAA 1777
                LST+ PA        P  P     + T+ G   S  P    +PP +      T ++
Sbjct: 4234 STTLLSTLPPAIEMTSTAPPSTPTA--PTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSS 4291

Query: 1778 FEKVLPKPESASVSA-APSP-PVSLP 1801
                    ++ + SA  P+P P+S P
Sbjct: 4292 SAPTPSTVQTTTTSAWTPTPTPLSTP 4317



 Score =  385 bits (990), Expect = e-106
 Identities = 428/1801 (23%), Positives = 620/1801 (34%), Gaps = 199/1801 (11%)

Query: 6    TETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQAS 65
            T  +  T    P P       P ++ ++ T  +    PT  P  +  P   P++     +
Sbjct: 2726 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT---PTPTPTGTQTPTTTPITTTTTVT 2782

Query: 66   PFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAP 125
            P P+P T   TP   P   +++ T  P  T  + PT  P      ++P           P
Sbjct: 2783 PTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--------TP 2833

Query: 126  TLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPK 185
            T   TP+++       + P          P    +P +  +  + +V     P     P 
Sbjct: 2834 TGTQTPTTTPITTTTTVTPTPT-------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2886

Query: 186  TNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVAS-LPQTTPTTTLAIASP 244
            T      + V P P  TP+     +T P    T +    +   +  P TTP TT    +P
Sbjct: 2887 TTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2944

Query: 245  -------QVKDTT-ISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPN 296
                   Q   TT I++       P     + P + P   + +    P  T +Q      
Sbjct: 2945 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ------ 2998

Query: 297  TPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSV 356
            TP   PI+  + + P    +       G   P+     T  T++   + TG   P+   +
Sbjct: 2999 TPTTTPITTTTTVTPTPTPT-------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3051

Query: 357  IP-------PLPSRNEV-----VPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATS 404
                     P P+  +      +  T    P   P+  + P+T + IT + + +     +
Sbjct: 3052 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPT 3110

Query: 405  FSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPT-----TTFEV 459
             + +PTT+ I  ++       P   Q P     TTP+  T   T    PT     TT  +
Sbjct: 3111 GTQTPTTTPITTTTTVTPTPTPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPI 3166

Query: 460  ATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSP-----PLPDPED 514
             T  +   +  P     PT+        V P    T   T    P++      P P P  
Sbjct: 3167 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3226

Query: 515  LKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQ 574
             +  P++  +   T       P   +    +P     TT   PT  P     P  +P   
Sbjct: 3227 TQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITT--TTTVTPTPTPTGTQTPTTTPITT 3283

Query: 575  STSSSP-------EIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYA 627
            +T+ +P       + P +   T        P P G    + T+P+   ++ +   T +  
Sbjct: 3284 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTPTPTPTGT 3342

Query: 628  GPDSAGPLLKSSLITPTVAAFPLESADPAGV-APTTAKGTSTYTTTASPFLEGTVSLAPK 686
               +  P+  ++ +TPT          P G   PTT   T+T T T +P   GT +  P 
Sbjct: 3343 QTPTTTPITTTTTVTPTPT--------PTGTQTPTTTPITTTTTVTPTPTPTGTQT--PT 3392

Query: 687  NHPVKEGTLTTLPLVPTASEN---CPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAG 743
              P+   T  T    PT ++     P+  +   T  P  T    P       + ++ P  
Sbjct: 3393 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3452

Query: 744  TPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSP 803
            TP GT+       T    P+ ++    PT     + T ++    T    +P+P       
Sbjct: 3453 TPTGTQ-------TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3505

Query: 804  QTKRPPTKKGSAGPD-TPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPK 862
             T  P T   +  P  TP G  +   +P+  +     + +  G++ +P TT   T  +  
Sbjct: 3506 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVT 3564

Query: 863  GAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKAR 922
              PTP+     +   +T     TPTP+      P   P T      P  + T +      
Sbjct: 3565 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3624

Query: 923  ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP 982
                   +  +P+P G  TP      +      TP+P    TP      +      TP+P
Sbjct: 3625 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3684

Query: 983  KGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP-- 1040
             G  TP      +      TP+P G  TP   TP +   +   TP P G  TP   TP  
Sbjct: 3685 TGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTP-TTTPIT 3742

Query: 1041 ------PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094
                  P+P  +   TP      TT   T      G  TP+     T    TP     G 
Sbjct: 3743 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3802

Query: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1154
             TP+          TP     G  TP      TT   TP     G  TP      TT   
Sbjct: 3803 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3862

Query: 1155 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1214
            TP     G  TP      TT   TP     G  TP+     TT   TP     G  TP+ 
Sbjct: 3863 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3922

Query: 1215 KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSL 1274
                TT   TP     G  TP+     TT   TP     G  TP      T    TP   
Sbjct: 3923 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3982

Query: 1275 KGGLATPPHKGAPNPAVVTP-PSPKG--GPATSPPKGAPTPPAATP-PSPKGSPGTPPPK 1330
              G  TP          VTP P+P G   P T+P     T    TP P+P G+  TP   
Sbjct: 3983 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQ-TPTTT 4038

Query: 1331 GAPTPPAVTP-PSPKGT---PTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTP 1386
               T   VTP P+P GT    T P TT ++     TP+  + PT    T +    P  TP
Sbjct: 4039 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4098

Query: 1387 PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPS---KGDLTPPAVTPVSL 1443
               +     P       +P   P   +    TP+T     TP+    G  T P  TP++ 
Sbjct: 4099 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITT 4157

Query: 1444 KKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAP 1503
                  +    G  TP++    T   VT       P P    T + P    +T AP+   
Sbjct: 4158 TTTVTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTGPPTHTST-APIAEL 4209

Query: 1504 TLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPA 1563
            T     P S    P T  S   P+  + TLLS   PA            MT  +P  TP 
Sbjct: 4210 TTSNPPPES--STPQTSRSTSSPLTESTTLLSTLPPAI----------EMTSTAPPSTPT 4257

Query: 1564 IPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS 1623
                  AP T S     SPP   PST    P       P   T+     APTP  V   +
Sbjct: 4258 ------APTTTSGGHTLSPP---PSTTTSPPG-----TPTRGTTTGSSSAPTPSTVQTTT 4303

Query: 1624 PEKGPATPAPKGTPTSPPVT-----PSS------LKDSPTSPAS-------------VTC 1659
                  TP P  TP+    T     PSS      L D+  +P               V C
Sbjct: 4304 TSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNC 4363

Query: 1660 KMGATVPQASKGLPAKKGPTALKEVLVAPAP-ESTPIITAPTRKGPQTKKSSATSPPICP 1718
             +  T+   +   P+   PT        P P +STP  + P+     +K +  T PP CP
Sbjct: 4364 SLSCTLEFYNWSCPSTPSPT--------PTPSKSTPTPSKPS--STPSKPTPGTKPPECP 4413

Query: 1719 D 1719
            D
Sbjct: 4414 D 4414



 Score =  310 bits (793), Expect = 1e-83
 Identities = 333/1289 (25%), Positives = 463/1289 (35%), Gaps = 179/1289 (13%)

Query: 716  NTCAPLATLVLAPEIPKSVPSP------SLPPAGTP--PGTKKVDGISHTSALAPVASS- 766
            N C P+   +  P  P + PSP      +LPP  TP  P T        T+   P+ ++ 
Sbjct: 1387 NCCWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTT 1446

Query: 767  -PKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRP--PTKKGSAGPDT--PI 821
             P    T     S T +   T T     PSP   + SP T  P  PT   +  P T  P 
Sbjct: 1447 TPPPTTTPSPPISTTTTPPPTTT-----PSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPS 1501

Query: 822  GNLSSPVSP-VEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSP--KGV 878
               ++P++P    + LP  +        SP TT + TPP P   P+P   TP++P     
Sbjct: 1502 PPTTTPITPPASTTTLPPTTTP------SPPTTTTTTPP-PTTTPSPPTTTPITPPTSTT 1554

Query: 879  TLPPKETPTP--SVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP 936
            TLPP  TP+P  +    P P   P+ P        ++T+++P        P     +P P
Sbjct: 1555 TLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPP 1614

Query: 937  KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSP 996
               P+PP  TP +P     T  P   P+PP  T         TP P   P+PP  T PSP
Sbjct: 1615 TTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT-------TTTPPPTTTPSPPTTTTPSP 1667

Query: 997  K-GGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKG 1055
                  TP P   P+ P  T PSP  +   TP P    T   ++P +   +P++T  P  
Sbjct: 1668 PITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSP----TTTPSSPITTTTTPSSTTTPSP 1723

Query: 1056 APTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKG 1115
             PTT   T PSP   P+ P+     T     PP+    P T +    P+PP+ TPP+   
Sbjct: 1724 PPTT--MTTPSPTTTPSPPT-----TTMTTLPPTTTSSPLTTT----PLPPSITPPT--- 1769

Query: 1116 GLATPPHKGAPTTPAATPPSPKGGLATPPPK-------------------GAPTTPAAT- 1155
               +P     PTTP     +  G L +  P                     A  +  AT 
Sbjct: 1770 --FSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATM 1827

Query: 1156 -PPSPKGGLA--------------TPPPKGAPTTPAA---------------TPPSPKGG 1185
             P  P G L                   K     P A               T P+    
Sbjct: 1828 YPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTT 1887

Query: 1186 LATPSPKGAPTTP-----AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA 1240
              T +P    TTP       TP     G  TP+     TT   TP     G  TP+    
Sbjct: 1888 TTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 1947

Query: 1241 PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP-PSPKG 1299
             TT   TP     G  TP      T    TP     G  TP          VTP P+P G
Sbjct: 1948 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2007

Query: 1300 --GPATSPPKGAPTPPAATP-PSPKGSPGTPPPKGAPTPPAVTP-PSPKGT---PTLPAT 1352
               P T+P     T    TP P+P G+  TP      T   VTP P+P GT    T P T
Sbjct: 2008 TQTPTTTP---ITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2063

Query: 1353 TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP 1412
            T ++     TP+  + PT    T +    P  TP   +     P       +P   P   
Sbjct: 2064 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2123

Query: 1413 KKAPATPVTREGAATPS---KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPA 1469
            +    TP+T     TP+    G  T P  TP++       +    G  TP++    T   
Sbjct: 2124 QTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2182

Query: 1470 VTP-PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPI- 1527
            VTP P+P     P     +++    P TP P G  T        P   P T ++   P  
Sbjct: 2183 VTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT--------PTTTPITTTTTVTPTP 2233

Query: 1528 APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPA-TPSSKEA-SSPPAV 1585
             PT T     TP T        P      +P  TP   T    P  TP+  +  ++ P  
Sbjct: 2234 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2293

Query: 1586 TPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPS 1645
            T +T    P+P     P   T+P        P  TP   +    TP    T  +P  TP+
Sbjct: 2294 TTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2351

Query: 1646 SLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP------APESTPIIT-- 1697
              +   T+P + T  +  T        P     T    V   P       P +TPI T  
Sbjct: 2352 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2411

Query: 1698 ----APTRKGPQTKKSS--ATSPPICPDPSAKNGSKGP-------LSTVAPAPLLPVQKD 1744
                 PT  G QT  ++   T+  + P P+   G++ P        +TV P P     + 
Sbjct: 2412 TVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2470

Query: 1745 SSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAP 1804
             + T      + +P       ++  +TP+T      V P P         + P++     
Sbjct: 2471 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTTV 2528

Query: 1805 SPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPT 1864
            +P PT  P     P++  +   +   P  P       P   P      +   + +   PT
Sbjct: 2529 TPTPT--PTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTP------ITTTTTVTPTPT 2579

Query: 1865 PKSAGIPVPTP-SAKQPVTKNNKGSGTES 1892
            P     P  TP +    VT     +GT++
Sbjct: 2580 PTGTQTPTTTPITTTTTVTPTPTPTGTQT 2608


>gi|163965362 nascent polypeptide-associated complex alpha subunit
            isoform b [Homo sapiens]
          Length = 215

 Score =  365 bits (938), Expect = e-100
 Identities = 197/214 (92%), Positives = 199/214 (92%)

Query: 1865 PKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDE 1924
            P  A   VP    + P  +   GSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDE
Sbjct: 2    PGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDE 61

Query: 1925 EPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYI 1984
            EPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYI
Sbjct: 62   EPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYI 121

Query: 1985 VFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDI 2044
            VFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDI
Sbjct: 122  VFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDI 181

Query: 2045 ELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 2078
            ELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM
Sbjct: 182  ELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 215



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 23/23 (100%), Positives = 23/23 (100%)

Query: 1  MPGEATETVPATEQELPQPQAET 23
          MPGEATETVPATEQELPQPQAET
Sbjct: 1  MPGEATETVPATEQELPQPQAET 23


>gi|5031931 nascent polypeptide-associated complex alpha subunit
            isoform b [Homo sapiens]
          Length = 215

 Score =  365 bits (938), Expect = e-100
 Identities = 197/214 (92%), Positives = 199/214 (92%)

Query: 1865 PKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDE 1924
            P  A   VP    + P  +   GSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDE
Sbjct: 2    PGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDE 61

Query: 1925 EPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYI 1984
            EPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYI
Sbjct: 62   EPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYI 121

Query: 1985 VFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDI 2044
            VFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDI
Sbjct: 122  VFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDI 181

Query: 2045 ELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 2078
            ELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM
Sbjct: 182  ELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 215



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 23/23 (100%), Positives = 23/23 (100%)

Query: 1  MPGEATETVPATEQELPQPQAET 23
          MPGEATETVPATEQELPQPQAET
Sbjct: 1  MPGEATETVPATEQELPQPQAET 23


>gi|163965364 nascent polypeptide-associated complex alpha subunit
            isoform b [Homo sapiens]
          Length = 215

 Score =  365 bits (938), Expect = e-100
 Identities = 197/214 (92%), Positives = 199/214 (92%)

Query: 1865 PKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDE 1924
            P  A   VP    + P  +   GSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDE
Sbjct: 2    PGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDE 61

Query: 1925 EPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYI 1984
            EPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYI
Sbjct: 62   EPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYI 121

Query: 1985 VFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDI 2044
            VFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDI
Sbjct: 122  VFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDI 181

Query: 2045 ELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 2078
            ELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM
Sbjct: 182  ELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 215



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 23/23 (100%), Positives = 23/23 (100%)

Query: 1  MPGEATETVPATEQELPQPQAET 23
          MPGEATETVPATEQELPQPQAET
Sbjct: 1  MPGEATETVPATEQELPQPQAET 23


>gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 3859

 Score =  330 bits (847), Expect = 7e-90
 Identities = 554/2146 (25%), Positives = 777/2146 (36%), Gaps = 371/2146 (17%)

Query: 10   PATEQELPQPQAETAVLPMSSA-LSVTAALGQPGPTLPPPCSPAPQQCPLSAAN----QA 64
            PA     P   A+  V+P++SA + +       GP +P   +  P   P+S+A+      
Sbjct: 452  PADTPGSPVTSADGPVVPVTSADIPLVPVTPPDGPVVPVTSADGPV-APVSSADGPVVPV 510

Query: 65   SPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIA 124
            +P  SP    +T  ++  P + + + +   T  E+P         PI P   A   P++ 
Sbjct: 511  TPADSPFIPVTTADDLIVPVTPADSPVLSVTPAESPAIPVTPADSPIVPVTPA-NGPVVP 569

Query: 125  PTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPP-SVAVAESGSVITLSA--PIAP 181
             T   +P      A   + P +   S   P     SP  SV +A+S +V    A  P+ P
Sbjct: 570  VTSADSPFVPVIPADGPVVPVTPADSPVVPVTPADSPVLSVTLADSPAVPVTPADSPVVP 629

Query: 182  SEPKTN-LNKVPSEVVPNPKGTPSPPCIVSTVPYHC-VTPMASIQSGVASLPQTT-PTTT 238
              P    +  V S   P    TP+   IVS  P      P+    S V  +     P   
Sbjct: 630  VTPADGPVVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVIP 689

Query: 239  LAIASPQVKDTTISSVLISP----QNPGS--LSLKGPVSPPAALSLSTQSLPVVTSSQKT 292
            +  A  ++   T +   I P      PGS   S  GPV P             VTS+   
Sbjct: 690  VTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSADGPVVP-------------VTSADSP 736

Query: 293  AGPNTPPDFPI----SLGSHLAPLHQSSFGSVQLLGQTGP----SALSDPTVKTISVDHS 344
              P TPPD P+    S    +AP+  +    V +    GP    S+   P V     D +
Sbjct: 737  FVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADTN 796

Query: 345  STGASYPSQRS-VIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVAT 403
                   S  S  +P +P+ + VVP T A  P+V                +P+ S  V  
Sbjct: 797  GPAVPVTSADSPFVPVIPADSPVVPVTPADDPIVP--------------VTPADSSFVPV 842

Query: 404  SFSLSPTTSLILKSSP---NATYHYPLVAQMPVSSV-----GTTPLVVTNPCTIAAAPTT 455
              + SP   +I    P   +++    +V   PV+ +         +V  NP      P T
Sbjct: 843  ISADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFADETVVPLNPADSPVIPVT 902

Query: 456  T-FEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPED 514
               ++   V+P  +  P++   P + A   + PV P +      T    PV P  P  + 
Sbjct: 903  PPDDLVVPVTP--TDCPVA---PVTSADCPVVPVTPADSPADPVTAADGPVVPFTPADDP 957

Query: 515  LKNL-PSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSF 573
            +  + P+   V   T  D   VP +   +PF P          P   P+V   P  SP+ 
Sbjct: 958  IVPVTPADSPVVSVTPADGPVVPVASADSPFVPVT--------PADDPIVSVTPAESPAI 1009

Query: 574  QSTSS--------SPEIPLSPEATLAKK-----SLGEPLPIGKPASSMTSPLGVNSSASV 620
              T +        S + P+SP  T   +     + G+P+    PA +  SP+  ++   V
Sbjct: 1010 PVTQADSPVVPVTSADRPVSPVTTADGRIVPVTAAGDPIVPVTPADTPGSPV-TSADGPV 1068

Query: 621  IKTDSYAGP-----DSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTA-- 673
            +   S   P        GP++  +     VA  P+ SAD   V  T+A G     ++A  
Sbjct: 1069 VPVTSADSPFVPVTPPDGPVVPVTSADGPVA--PVSSADGPVVPVTSADGPVAPVSSADG 1126

Query: 674  ---------SPFLEGT------VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTC 718
                     SPF+  T      V + P + PV   TL   P+VP    + PV P P    
Sbjct: 1127 PVVPVTPADSPFIPVTTADDPIVPVTPADSPVLSVTLADSPVVPVTPADSPVIPVPPAN- 1185

Query: 719  APLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGAS 778
                     P +P S       P     G   +D  S T  L    S     PT+     
Sbjct: 1186 --------GPVVPVSSADSPFVPVIPADGLVVLD--SSTDVLVVPVS-----PTDGILVP 1230

Query: 779  ATASSKGTLTYLADSP----SPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEAS 834
              A        +ADSP    +P    V P T            D+P+  L +PV PV + 
Sbjct: 1231 DLADDPVVSVTIADSPVIPVTPADSPVVPVTSADSPVVPVTPADSPV-ILVTPVGPVVSV 1289

Query: 835  FLPENSLSFQGSKDSPA----TTHSP----TPPSPKGAPTPSA------VTPLSPKGVTL 880
               +  +    + DSP     +  SP    TP      P  SA      VTP     V +
Sbjct: 1290 TTADGPVVLVSTADSPVIPVTSADSPVVPVTPADGPVVPVTSADSPFVPVTPADDPIVPV 1349

Query: 881  PPKETPTPSVVNLPFPKEGPATPA-PKQAPALSMTSS-SPKKARATPAPKGIPASPSPKG 938
             P ++P  SV     P E PA P  P  +P + +TS+ SP     T   + +P +P+   
Sbjct: 1350 TPADSPIVSVT----PAESPAIPVTPADSPVVPVTSADSPLIPLTTAGSRVVPVTPTGDP 1405

Query: 939  -APTPPAATPPSP---KGGPATP-SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP 993
              P  PA TP SP     GP  P +P   P  P  TP    G P T +    P  P  TP
Sbjct: 1406 IVPVTPADTPGSPVTSADGPVVPVTPAGDPIVPV-TPADTPGSPVTSAD--GPVVPVTTP 1462

Query: 994  PSPKGGPATP-SPKGAPTPPAVTPPSP--KGSPAATPFPKGASTPPAATPPSPKGSPAAT 1050
                 GP  P SP   P  P  +   P    +PA +PF    +      P +P  SP   
Sbjct: 1463 D----GPLVPVSPPDGPVVPVTSADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVVP 1518

Query: 1051 PLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPA-------------ATPPSPKGGPATP 1097
              P   P  P      P     +      P  PA               P SP  G   P
Sbjct: 1519 VTPADIPVVPVTPANGPVIHVTSADCPFVPVIPADGLVALDSSTDVLVVPVSPTDGVLVP 1578

Query: 1098 SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1157
                 P+       SP   +        P T A  P  P   +  P     P TPA  P 
Sbjct: 1579 DLADDPVVSVTIADSPVIPVTPADSTVVPVTLADGPVVPVTSVDIPV---VPVTPANGPV 1635

Query: 1158 SPKGGLATP-----PPKGA--PTTPA---ATPPSPKGGLATP-SPKGAPTTPAATPPSPK 1206
            +P   +  P     P  G+  P T A     P +P  GL  P +P  +P  P     SP 
Sbjct: 1636 APVTPVDDPVVSVNPADGSVVPVTSADCPVVPVTPADGLVVPVTPADSPIVPVTPADSPV 1695

Query: 1207 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP-KGGPATPPPKGAPT 1265
              + +      P TPA +P  P     T SP G+P T A  P  P     + P P     
Sbjct: 1696 VLVTSADSPVIPVTPADSPVVPVTSADTDSP-GSPVTSADGPVVPVTSADSLPVPVTPAD 1754

Query: 1266 PPAATPPSLKGGLATPPHKGAPNPAV-VTP-------------PSPKGGPATSPPKGAPT 1311
             P     S  G +A  P   A  P V VTP             P+    PA SP    P 
Sbjct: 1755 GPVVPVTSADGPVA--PVSSADGPVVPVTPADSPVVPVTTADDPTVPVTPADSPV--VPV 1810

Query: 1312 PPAATPPSPKGSPGTP-----PPKG-----APTPPAVTPPSPKG---------TPTLPAT 1352
            PPA  P  P  S  +P     P  G     + T   V P SP            P +  T
Sbjct: 1811 PPANGPIVPVTSADSPFVPVIPADGLVVLDSSTDVLVVPVSPTDGILVPDLADDPVVSVT 1870

Query: 1353 TPSSKGGPTTPSSK--------EGPTPPAATPSHKGGPAMTPPSPKRGPAIP-SPKGDPT 1403
               S   P TP+          +GP  P  +  +     + P +P   P IP +P  DP 
Sbjct: 1871 IADSPVIPVTPADSPVVLVTPADGPVVPVTSVDNP----VVPVTPADNPVIPVTPVDDP- 1925

Query: 1404 SPAVIPLSPKKAPATPVTREGA----ATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATP 1459
               V+P++P   P  PVT   +     TP+   + P  VTP      P  SA    P  P
Sbjct: 1926 ---VVPVTPADDPIVPVTSADSPIVSVTPADSPVFP--VTPADSPVIPVASADS--PLVP 1978

Query: 1460 SSKGD----PTLPA---VTPPSPKEPPA--------PKQVATSSSPKKAPATPAPMGAPT 1504
             +  D    P +PA   V P +P E PA        P    TS+     P T      P 
Sbjct: 1979 VTPADMVVVPVIPADGPVIPVTPAESPAIPVTPTDSPVVPVTSADSPVIPVTADSPFVPV 2038

Query: 1505 LPA---VIPSSPKE---VPATP---------------------SSRRDPIAPTATLLSKK 1537
             PA   VIP +P +   VP TP                     +S  DP+ P    +   
Sbjct: 2039 TPADSPVIPVTPPDDLVVPVTPIDCPVVPVTLVDCPVVSVTPANSPVDPVTPADGPVVPV 2098

Query: 1538 TPAT-----LAPKEALIPPAMTVPS------PKKTPAIP-TPKEAPATPSSKEASSPPAV 1585
            TPA      + P + LI P     S      P  +P +P TP ++P    +   S    V
Sbjct: 2099 TPADSPVIPVTPADDLIVPVTPADSLIVSVTPADSPVVPVTPADSPVISVASADSPVVPV 2158

Query: 1586 TPSTYKGAP-SPKELLIPPAVTSPSPKEAPTP---------PA---VTPPSPEKGPATPA 1632
            TP+     P +P +  + P   + SP    TP         PA   V P +P   P  P 
Sbjct: 2159 TPADTVVVPVTPADGPVIPVTPAESPAIPVTPADSPVVPVTPADDPVVPVTPADSPIVPV 2218

Query: 1633 PKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPA-PE 1691
            P   P S PV P +  D+P SP  V    G  VP  S   P    P    +  V P  P 
Sbjct: 2219 P---PASDPVVPVTPADTPGSP--VASADGPVVPVTSADSPLV--PVTPGDSPVVPVTPA 2271

Query: 1692 STPIITAPTRKGPQTKKSSATSP--PICP--DPSAK-NGSKGPLSTVAPA--PLLPVQKD 1744
             +P+    +  GP    + A  P  P+ P  DP    + +  P+  V PA  P++PV   
Sbjct: 2272 DSPVFPVTSADGPVFPVTLADDPVFPVTPADDPIFPVSPADSPVVPVTPANIPVVPVPPA 2331

Query: 1745 SSKTAKGKDASHSPKGPLAPPES----KASTPLTAAAFEKV--LPKPESA-----SVSAA 1793
            +        A  SP  P+ P +      +ST +          +P P+ A     SV+ +
Sbjct: 2332 NGSVVPVTSAG-SPFVPIIPADGLVVLDSSTDVLVVLVSPTDGIPVPDLADDPVVSVTTS 2390

Query: 1794 PSP--PVS------LPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIP 1845
             SP  PV+      +P+AP+  P +P      P  P    +SP  P+ PAD   ++P  P
Sbjct: 2391 DSPVIPVTPTDSPVVPVAPADGPVVPVTSVDSPVVPVTPADSPVIPVTPAD-SLVVPATP 2449

Query: 1846 -PEPISGGVPFQSVLVNMPTPKSAGIPV-PTPSAKQPVTKNNKGSG 1889
              +P+    P    +V + T   A IPV    SA  PV       G
Sbjct: 2450 ADDPVVSVTPADGPVVPVTT---ADIPVISVTSADSPVVPVTPADG 2492



 Score =  320 bits (821), Expect = 7e-87
 Identities = 528/2143 (24%), Positives = 746/2143 (34%), Gaps = 345/2143 (16%)

Query: 3    GEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAAN 62
            G      PA    +P   A++ V+ ++S  S    +      + P         P+ +A+
Sbjct: 206  GPVVHVTPANGTVVPVTPADSPVVTVASTDSPVVPVTPADDPIVPVTPADSSFVPVISAD 265

Query: 63   QASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPE----APTFLPNLIGPPISPAALAL 118
              SPF     +   P + P    SS   L +   P      P F    I       +L +
Sbjct: 266  --SPF-----VPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFADETIXXXXXXXSLVV 318

Query: 119  A-----SPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVI 173
            +      P++  T   +P  S  LA   + P +    S F P +    P V V  + S +
Sbjct: 319  SVTTADDPIVPVTPADSPVLSVTLADSPVVPVT-PADSPFVPAIPADGPVVPVTPADSPV 377

Query: 174  TLSAPIAPSE-PKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHC-VTPMASIQSGVASLP 231
                P+ P++ P  ++    S  VP    TP+   IVS  P    V P+ S  S +  +P
Sbjct: 378  V---PVTPADGPVVSVASADSPFVPV---TPADDPIVSVTPADSPVVPVTSADSPL--IP 429

Query: 232  QTTPTTTLAIASPQVKDTTISSVLISP----QNPGS--LSLKGPVSPPAALSLSTQSLPV 285
             TT       A  +V   T +   I P      PGS   S  GPV P             
Sbjct: 430  VTT-------ADGRVVPVTAAGDPIVPVTPADTPGSPVTSADGPVVP------------- 469

Query: 286  VTSSQKTAGPNTPPDFPI----SLGSHLAPLHQSSFGSVQLLGQTGPS---ALSDPTVKT 338
            VTS+     P TPPD P+    S    +AP+  +    V +     P      +D  +  
Sbjct: 470  VTSADIPLVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDLIVP 529

Query: 339  ISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVV------APSVDKGPSTISSIT 392
            ++   S   +  P++   IP  P+ + +VP T A  PVV      +P V   P+    + 
Sbjct: 530  VTPADSPVLSVTPAESPAIPVTPADSPIVPVTPANGPVVPVTSADSPFVPVIPADGPVVP 589

Query: 393  CSPSGSLNVATSFSLSPTTSLILKSSPNATY---HYPLV----AQMPVSSVGTT------ 439
             +P+ S  V  + + SP  S+ L  SP         P+V    A  PV  V +       
Sbjct: 590  VTPADSPVVPVTPADSPVLSVTLADSPAVPVTPADSPVVPVTPADGPVVPVASADSPFVP 649

Query: 440  ------PLVVTNPCTIAAAPTTTFE--VATCVSPPMSSGPISN----IEPTSPAALVMAP 487
                  P+V   P    A P T  +  V    S      P++     I P + A   + P
Sbjct: 650  VTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVIPVTTADGRIVPVTAAGDPIVP 709

Query: 488  VAPKEPSTQVATTLRIPVSPPLP-DPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSP 546
            V P +      T+   PV P    D   +   P    V   T  D    P S    P  P
Sbjct: 710  VTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVVP 769

Query: 547  AQAG-----LTTKKDPTVLPLVQAAPKNSPSFQSTSS-SPEIPLSP--EATLAKKSLGEP 598
              +        +  D  V+P V  A  N P+   TS+ SP +P+ P     +      +P
Sbjct: 770  VTSADGPVAPVSSADGPVVP-VTPADTNGPAVPVTSADSPFVPVIPADSPVVPVTPADDP 828

Query: 599  LPIGKPASSMTSPLGVNSSASVIKTDSYAGP--DSAGPLL-KSSLITPTVAAFPLESADP 655
            +    PA S   P        VI  DS   P   + GP++  SS     V  FP+     
Sbjct: 829  IVPVTPADSSFVP--------VISADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCI-- 878

Query: 656  AGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAP-SP 714
              + P  A  T       +P     + + P +  V   T T  P+ P  S +CPV P +P
Sbjct: 879  --LVPAFADET---VVPLNPADSPVIPVTPPDDLVVPVTPTDCPVAPVTSADCPVVPVTP 933

Query: 715  QNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKE----C 770
             ++ A   T    P +P +     + P  TP  +  V        + PVAS+        
Sbjct: 934  ADSPADPVTAADGPVVPFTPADDPIVPV-TPADSPVVSVTPADGPVVPVASADSPFVPVT 992

Query: 771  PTEDSGASAT-ASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVS 829
            P +D   S T A S       ADSP     S         T  G   P T  G+   PV+
Sbjct: 993  PADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVSPVTTADGRIVPVTAAGDPIVPVT 1052

Query: 830  PVEASFLPENSLSFQ----GSKDSPATTHSPTPPSPKGAPTPSAVTPLSP----KGVTLP 881
            P +    P  S         S DSP      TPP     P  SA  P++P     G  +P
Sbjct: 1053 PADTPGSPVTSADGPVVPVTSADSPFVP--VTPPDGPVVPVTSADGPVAPVSSADGPVVP 1110

Query: 882  PKETPTPSVVNLPFPKEGPATPA-PKQAPALSMTSSSPKKARATPAPKGIPA-----SPS 935
                  P  V      +GP  P  P  +P + +T++       TPA   + +     SP 
Sbjct: 1111 VTSADGP--VAPVSSADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVLSVTLADSPV 1168

Query: 936  PKGAPTPPAATPPSPKGGPATP-----SPKWAPTPPA-------------ATPPSPKGGP 977
                P      P  P  GP  P     SP + P  PA               P SP  G 
Sbjct: 1169 VPVTPADSPVIPVPPANGPVVPVSSADSP-FVPVIPADGLVVLDSSTDVLVVPVSPTDGI 1227

Query: 978  ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA------VTPPSPKGSPAATPFPKG 1031
              P     P        SP   P TP+   +P  P       V P +P  SP     P G
Sbjct: 1228 LVPDLADDPVVSVTIADSPVI-PVTPAD--SPVVPVTSADSPVVPVTPADSPVILVTPVG 1284

Query: 1032 ---------------ASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSL 1076
                           ++      P +   SP     P   P  P  +  SP   P TP+ 
Sbjct: 1285 PVVSVTTADGPVVLVSTADSPVIPVTSADSPVVPVTPADGPVVPVTSADSPFV-PVTPAD 1343

Query: 1077 KG-APTPPAATP---PSPKGGPATP-SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA 1131
                P  PA +P    +P   PA P +P  +P+ P  +  SP   L T   +  P TP  
Sbjct: 1344 DPIVPVTPADSPIVSVTPAESPAIPVTPADSPVVPVTSADSPLIPLTTAGSRVVPVTPTG 1403

Query: 1132 TPPSPKGGLATP--PPKGA-----PTTPAATPPSPKGGLATPPPKGAPTTPAATP----P 1180
             P  P     TP  P   A     P TPA  P  P     TP   G+P T A  P     
Sbjct: 1404 DPIVPVTPADTPGSPVTSADGPVVPVTPAGDPIVPVTPADTP---GSPVTSADGPVVPVT 1460

Query: 1181 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA 1240
            +P G L   SP   P  P  +   P   +   +P  +P  P  T   P   +        
Sbjct: 1461 TPDGPLVPVSPPDGPVVPVTSADGP---VVPVTPADSPFIPVTTADDPIVPVTPADSPVV 1517

Query: 1241 PTTPA---ATPPSPKGGPA--------------------------------TPPPKGAPT 1265
            P TPA     P +P  GP                                   P  G   
Sbjct: 1518 PVTPADIPVVPVTPANGPVIHVTSADCPFVPVIPADGLVALDSSTDVLVVPVSPTDGVLV 1577

Query: 1266 PPAATPPSLKGGLA-TPPHKGAPNPAVVTPPSPKGGPATSPPKG----APTPPAATPPSP 1320
            P  A  P +   +A +P     P  + V P +   GP            P  PA  P +P
Sbjct: 1578 PDLADDPVVSVTIADSPVIPVTPADSTVVPVTLADGPVVPVTSVDIPVVPVTPANGPVAP 1637

Query: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS-SKEGPTPPAATPS-- 1377
                  P     P   +V P +    P +P T       P TP+ S   P  PA +P   
Sbjct: 1638 VTPVDDPVVSVNPADGSVVPVTSADCPVVPVTPADGLVVPVTPADSPIVPVTPADSPVVL 1697

Query: 1378 -HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGA----ATPSKGD 1432
                   + P +P   P +P    D  SP   P++    P  PVT   +     TP+ G 
Sbjct: 1698 VTSADSPVIPVTPADSPVVPVTSADTDSPGS-PVTSADGPVVPVTSADSLPVPVTPADGP 1756

Query: 1433 LTPPA-----VTPVSLKKAPATSA-PKGGPATP-SSKGDPTLPAVTPPSPKEPPAPKQ-- 1483
            + P       V PVS    P     P   P  P ++  DPT+P     SP  P  P    
Sbjct: 1757 VVPVTSADGPVAPVSSADGPVVPVTPADSPVVPVTTADDPTVPVTPADSPVVPVPPANGP 1816

Query: 1484 --VATSSSPKKAPATPAP----MGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK 1537
                TS+     P  PA     + + T   V+P SP +    P    DP+       S  
Sbjct: 1817 IVPVTSADSPFVPVIPADGLVVLDSSTDVLVVPVSPTDGILVPDLADDPVVSVTIADSPV 1876

Query: 1538 TPATLA--------PKEALIPPAMTVPSP------KKTPAIP-----------TPKEAPA 1572
             P T A        P +  + P  +V +P         P IP           TP + P 
Sbjct: 1877 IPVTPADSPVVLVTPADGPVVPVTSVDNPVVPVTPADNPVIPVTPVDDPVVPVTPADDPI 1936

Query: 1573 TPSSKEASSPPAVTPSTYKGAP-SPKELLIPPAVTSPSPKEAPTPP--AVTPPSPEKGPA 1629
             P +   S   +VTP+     P +P +  + P  ++ SP    TP    V P  P  GP 
Sbjct: 1937 VPVTSADSPIVSVTPADSPVFPVTPADSPVIPVASADSPLVPVTPADMVVVPVIPADGPV 1996

Query: 1630 -------TPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALK 1682
                   +PA   TPT  PV P +  DSP  P +         P  S  +P     T   
Sbjct: 1997 IPVTPAESPAIPVTPTDSPVVPVTSADSPVIPVTADSPFVPVTPADSPVIPV----TPPD 2052

Query: 1683 EVLVAPAPESTPIITAPTRKGPQTKKSSATSP--PICPDPSAKNGSKGPLSTVAPA--PL 1738
            +++V   P   P++       P    + A SP  P+ P       + GP+  V PA  P+
Sbjct: 2053 DLVVPVTPIDCPVVPVTLVDCPVVSVTPANSPVDPVTP-------ADGPVVPVTPADSPV 2105

Query: 1739 LPVQKDSS-----KTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAA 1793
            +PV            A     S +P      P + A +P+ + A        +S  V   
Sbjct: 2106 IPVTPADDLIVPVTPADSLIVSVTPADSPVVPVTPADSPVISVA------SADSPVVPVT 2159

Query: 1794 PSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPE-PISGG 1852
            P+  V +P+ P+  P +P      P+ P    +SP  P+ PAD D ++P+ P + PI   
Sbjct: 2160 PADTVVVPVTPADGPVIPVTPAESPAIPVTPADSPVVPVTPAD-DPVVPVTPADSPIVPV 2218

Query: 1853 VPFQSVLVNMPTPKSAGIP--------VPTPSAKQPVTKNNKG 1887
             P    +V +    + G P        VP  SA  P+     G
Sbjct: 2219 PPASDPVVPVTPADTPGSPVASADGPVVPVTSADSPLVPVTPG 2261



 Score =  316 bits (810), Expect = 1e-85
 Identities = 495/1937 (25%), Positives = 712/1937 (36%), Gaps = 301/1937 (15%)

Query: 10   PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPS 69
            PA    +P  QA++ V+P++SA    + +      + P  +      P++ A+      S
Sbjct: 1003 PAESPAIPVTQADSPVVPVTSADRPVSPVTTADGRIVPVTAAGDPIVPVTPADTPG---S 1059

Query: 70   PSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKG 129
            P T A  P+    P +S+ +     T P+ P         P++P + A    +   +  G
Sbjct: 1060 PVTSADGPV---VPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADG 1116

Query: 130  --TPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTN 187
               P SSA   +V + P      S F P      P V V  + S + LS  +A S P   
Sbjct: 1117 PVAPVSSADGPVVPVTP----ADSPFIPVTTADDPIVPVTPADSPV-LSVTLADS-PVVP 1170

Query: 188  LNKVPSEVVPNPKGT-PSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIAS--- 243
            +    S V+P P    P  P   +  P+  V P      G+  L  +T    + ++    
Sbjct: 1171 VTPADSPVIPVPPANGPVVPVSSADSPFVPVIPA----DGLVVLDSSTDVLVVPVSPTDG 1226

Query: 244  ---PQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPD 300
               P + D  + SV I+             SP   ++ +   +  VTS+     P TP D
Sbjct: 1227 ILVPDLADDPVVSVTIAD------------SPVIPVTPADSPVVPVTSADSPVVPVTPAD 1274

Query: 301  FPISLGSHLAPLHQSSFGSVQLLGQTGP----SALSDPTVKTISVDHSSTGASYPSQRSV 356
             P+ L + + P+       V +    GP    S    P +   S D      + P+   V
Sbjct: 1275 SPVILVTPVGPV-------VSVTTADGPVVLVSTADSPVIPVTSADSPVVPVT-PADGPV 1326

Query: 357  IPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFS-LSPTTSLIL 415
            +P   + +  VP T A  P+V   V    S I S+T + S ++ V  + S + P TS   
Sbjct: 1327 VPVTSADSPFVPVTPADDPIVP--VTPADSPIVSVTPAESPAIPVTPADSPVVPVTSADS 1384

Query: 416  KSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNI 475
               P  T    +V   PV+  G  P+V   P     +P T+           + GP+   
Sbjct: 1385 PLIPLTTAGSRVV---PVTPTGD-PIVPVTPADTPGSPVTS-----------ADGPVV-- 1427

Query: 476  EPTSPAALVMAPVAPKEPSTQVATTLRIPVSP-PLPDPEDLKNLPSSVLVKFPTQKDLQT 534
             P +PA   + PV P +      T+   PV P   PD   +   P    V   T  D   
Sbjct: 1428 -PVTPAGDPIVPVTPADTPGSPVTSADGPVVPVTTPDGPLVPVSPPDGPVVPVTSADGPV 1486

Query: 535  VPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSS-PEIPLSPE--ATLA 591
            VP +   +PF P    +TT  DP    +V   P +SP    T +  P +P++P     + 
Sbjct: 1487 VPVTPADSPFIP----VTTADDP----IVPVTPADSPVVPVTPADIPVVPVTPANGPVIH 1538

Query: 592  KKSLGEPLPIGKPASSMTSPLGVNSSASVI-----KTDSYAGPDSAGPLLKSSLITPTVA 646
              S   P     PA  + +   ++SS  V+      TD    PD A   + S  I  +  
Sbjct: 1539 VTSADCPFVPVIPADGLVA---LDSSTDVLVVPVSPTDGVLVPDLADDPVVSVTIADS-P 1594

Query: 647  AFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLV----- 701
              P+  AD   V  T A G     T+        V + P N PV   T    P+V     
Sbjct: 1595 VIPVTPADSTVVPVTLADGPVVPVTSVDI---PVVPVTPANGPVAPVTPVDDPVVSVNPA 1651

Query: 702  -----PTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISH 756
                 P  S +CPV P       P   LV+ P  P   P   + PA +P        +  
Sbjct: 1652 DGSVVPVTSADCPVVP-----VTPADGLVV-PVTPADSPIVPVTPADSPV-------VLV 1698

Query: 757  TSALAPVAS-SPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSA 815
            TSA +PV   +P + P      SA   S G+    AD P    V V+     P     + 
Sbjct: 1699 TSADSPVIPVTPADSPVVPV-TSADTDSPGSPVTSADGPV---VPVTSADSLPVPVTPAD 1754

Query: 816  GPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATT-HSPTPPSPKGAPTPSAVTPLS 874
            GP  P+ +   PV+PV ++  P   ++   S   P TT   PT P          VTP  
Sbjct: 1755 GPVVPVTSADGPVAPVSSADGPVVPVTPADSPVVPVTTADDPTVP----------VTPAD 1804

Query: 875  PKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASP 934
               V +PP   P   V +     + P  P       + + SS+            +P SP
Sbjct: 1805 SPVVPVPPANGPIVPVTSA----DSPFVPVIPADGLVVLDSSTDVLV--------VPVSP 1852

Query: 935  SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPAT-PSPKGAPTPPAATP 993
            +  G   P  A  P         S   A +P    P +P   P    +P   P  P  + 
Sbjct: 1853 TD-GILVPDLADDP-------VVSVTIADSP--VIPVTPADSPVVLVTPADGPVVPVTSV 1902

Query: 994  PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053
             +P   P TP+         V  P    +PA  P     S        +P  SP     P
Sbjct: 1903 DNPVV-PVTPADNPVIPVTPVDDPVVPVTPADDPIVPVTSADSPIVSVTPADSPVFPVTP 1961

Query: 1054 KGAPTTPAATLPSPKGGPATPS-LKGAPTPPA---ATPPSPKGGPATP-SPKGAPMPPAA 1108
              +P  P A+  SP   P TP+ +   P  PA     P +P   PA P +P  +P+ P  
Sbjct: 1962 ADSPVIPVASADSPL-VPVTPADMVVVPVIPADGPVIPVTPAESPAIPVTPTDSPVVPVT 2020

Query: 1109 TPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPP 1168
            +  SP      P    +P  P     SP   +  P     P TP   P  P   +  P  
Sbjct: 2021 SADSP----VIPVTADSPFVPVTPADSPVIPVTPPDDLVVPVTPIDCPVVPVTLVDCPVV 2076

Query: 1169 KGAPTTPAATPPSPKGGLATP-SPKGAPTTPAA------TPPSPKGGL-ATPSPKGAPTT 1220
               P      P +P  G   P +P  +P  P         P +P   L  + +P  +P  
Sbjct: 2077 SVTPANSPVDPVTPADGPVVPVTPADSPVIPVTPADDLIVPVTPADSLIVSVTPADSPVV 2136

Query: 1221 PAATPPSPKGGLATPSPKGAPTTPAAT---PPSPKGGPATP-PPKGAPTPPAATPPSLKG 1276
            P     SP   +A+      P TPA T   P +P  GP  P  P  +P  P  TP     
Sbjct: 2137 PVTPADSPVISVASADSPVVPVTPADTVVVPVTPADGPVIPVTPAESPAIP-VTPADSPV 2195

Query: 1277 GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA----PTPPAATPPSPKGSPGTP--PPK 1330
               TP    A +P  V P +P   P    P  +    P  PA TP SP  S   P  P  
Sbjct: 2196 VPVTP----ADDP--VVPVTPADSPIVPVPPASDPVVPVTPADTPGSPVASADGPVVPVT 2249

Query: 1331 GAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPP---AATPSHKGGPA---M 1384
             A +P  + P +P  +P +P T   S   P T  S +GP  P   A  P     PA   +
Sbjct: 2250 SADSP--LVPVTPGDSPVVPVTPADSPVFPVT--SADGPVFPVTLADDPVFPVTPADDPI 2305

Query: 1385 TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGA----ATPSKGDLTPPAVTP 1440
             P SP   P +P     P +  V+P+ P      PVT  G+      P+ G +   + T 
Sbjct: 2306 FPVSPADSPVVPV---TPANIPVVPVPPANGSVVPVTSAGSPFVPIIPADGLVVLDSSTD 2362

Query: 1441 VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATP-AP 1499
            V +       +P  G   P    DP +   T  SP  P          +P  +P  P AP
Sbjct: 2363 VLV----VLVSPTDGIPVPDLADDPVVSVTTSDSPVIP---------VTPTDSPVVPVAP 2409

Query: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPK 1559
               P +P     SP  VP TP+    P+ P            + P ++L+ PA    +P 
Sbjct: 2410 ADGPVVPVTSVDSP-VVPVTPAD--SPVIP------------VTPADSLVVPA----TPA 2450

Query: 1560 KTPAIP-TPKEAPATPSSKEASSPPAVTPSTYKGAP-SPKELLIPPAVTSPSPKEAPTPP 1617
              P +  TP + P  P +       +VT +     P +P + L+ P VTS      P  P
Sbjct: 2451 DDPVVSVTPADGPVVPVTTADIPVISVTSADSPVVPVTPADGLVVP-VTSADSVVVPATP 2509

Query: 1618 AVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKG 1677
            A  P  P     +P    TP   PV   +  DSP  P  VT    + VP    G+P    
Sbjct: 2510 ADCPLVPVDPADSPIVLFTPYDNPVVSVTSDDSPVFP--VTPADSSVVPVTPAGVP---- 2563

Query: 1678 PTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSP--PICPDPSAKNGSKGPLSTVAP 1735
                   +V   P   P++            +SA SP  P+ P  S       P+  V+P
Sbjct: 2564 -------VVPVTPGDGPVVPVTPADSLVVPVTSADSPVFPVTPADS-------PVFPVSP 2609

Query: 1736 A------------PLLPVQKDSSKTAKGKDASHSPKGPLAP--PESKASTPLTAA--AFE 1779
            A            P++PV    S       A     GP+ P  P +    P+T+A   F 
Sbjct: 2610 ADDLVVPVTPGDSPVVPVSPADSPVVLVTPAD----GPVVPVTPANGPVVPVTSADSPFV 2665

Query: 1780 KVLPK------PESASVSAAPSPPVSLPLAPS-----PVPTLPPKQQFLPSSPGLVLESP 1828
             V+P         S  V   P  P    L P       VP  P     +P +PG   + P
Sbjct: 2666 PVIPADGLVVLDSSTDVLVVPVFPTDGILVPDLADDPVVPVTPGDDPVVPVTPG---DDP 2722

Query: 1829 SKPLAPADEDELLPLIP 1845
              P+ PAD+   +P+ P
Sbjct: 2723 VIPVTPADDGPFVPVTP 2739



 Score =  275 bits (704), Expect = 3e-73
 Identities = 469/1815 (25%), Positives = 645/1815 (35%), Gaps = 256/1815 (14%)

Query: 261  PGSLSLKGPVSPPAALSLSTQ-SLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGS 319
            PGS     PV  P  + + T  S+  VT +     P  P D  + L S    L    F +
Sbjct: 21   PGS-----PVVLPITVVVQTDGSVVPVTRAGSPFVPVIPADGLVVLDSSTDVLVVPVFPA 75

Query: 320  VQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAP 379
              +L    P    +P V     D      + P+   VIP   + + VVP T A  PVV  
Sbjct: 76   DGILV---PDFADNPVVPVTPADDLVFPVT-PADSPVIPVTSADDPVVPITPADNPVVPV 131

Query: 380  SVDKGPSTISSITCSPSGSLNVATS----FSLSPTTSLILKSSPNATYHYPLVAQMPVSS 435
            +   GP  +  +T + S    VA++      ++P  S +   +P  +   PL    P  S
Sbjct: 132  TSANGP--VIPVTPADSPVFPVASADGPVVPVTPADSPVFPVTPADS---PLFPVTPADS 186

Query: 436  VGTTPLVVTNPCTIAAAPTT---------TFEVATCVSPPMSSGPI-------SNIEPTS 479
                PL    P   AA P T         T    T V    +  P+       S + P +
Sbjct: 187  ----PLFPVTPADSAAIPVTPADGPVVHVTPANGTVVPVTPADSPVVTVASTDSPVVPVT 242

Query: 480  PAALVMAPVAPKEPSTQVATTLRIPVSPPLP-DPEDLKNLPSSVLVKFPTQKDLQTVPAS 538
            PA   + PV P + S     +   P  P +P D   + +  + VLV      +   VPA 
Sbjct: 243  PADDPIVPVTPADSSFVPVISADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAF 302

Query: 539  LE-----GAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQST-SSSPEIPLSPEATLAK 592
             +               +TT  D    P+V   P +SP    T + SP +P++P  +   
Sbjct: 303  ADETIXXXXXXXSLVVSVTTADD----PIVPVTPADSPVLSVTLADSPVVPVTPADSPFV 358

Query: 593  KSL---GEPLPIGKPASSMTSPL--GVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAA 647
             ++   G  +P+  PA S   P+        SV   DS   P +       S+       
Sbjct: 359  PAIPADGPVVPV-TPADSPVVPVTPADGPVVSVASADSPFVPVTPADDPIVSVTPADSPV 417

Query: 648  FPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASEN 707
             P+ SAD   +  TTA G     T A    +  V + P + P    T    P+VP  S +
Sbjct: 418  VPVTSADSPLIPVTTADGRVVPVTAAG---DPIVPVTPADTPGSPVTSADGPVVPVTSAD 474

Query: 708  CPVAP--SPQNTCAPLATL--VLAPEIPKSVPSPSLPPAGTP--PGTKKVDGI-SHTSAL 760
             P+ P   P     P+ +    +AP      P   + PA +P  P T   D I   T A 
Sbjct: 475  IPLVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDLIVPVTPAD 534

Query: 761  APVAS-SPKECPT-----EDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGS 814
            +PV S +P E P       DS       + G +  +  + SP  V V P          +
Sbjct: 535  SPVLSVTPAESPAIPVTPADSPIVPVTPANGPVVPVTSADSPF-VPVIP----------A 583

Query: 815  AGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPAT-THSP----TPPSPKGAPTPSA 869
             GP  P+    SPV PV  +  P  S++   S   P T   SP    TP      P  SA
Sbjct: 584  DGPVVPVTPADSPVVPVTPADSPVLSVTLADSPAVPVTPADSPVVPVTPADGPVVPVASA 643

Query: 870  VTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPK-QAPALSMTSSSPKKARATPAPK 928
             +P  P    + P + P  SV     P E PA P  +  +P + +TS+       T A  
Sbjct: 644  DSPFVP----VTPADDPIVSVT----PAESPAIPVTQADSPVVPVTSADRPVIPVTTADG 695

Query: 929  GI---PASPSPKGAPTPPAATPPSP---KGGPATP-----SPKWAPTPP--AATPPSPKG 975
             I    A+  P   P  PA TP SP     GP  P     SP    TPP     P +   
Sbjct: 696  RIVPVTAAGDPI-VPVTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVTSAD 754

Query: 976  GPATP-SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT-PPSPKGSPAATPFPKGAS 1033
            GP  P S    P  P  +   P    ++      P  PA T  P+   + A +PF     
Sbjct: 755  GPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADTNGPAVPVTSADSPFVPVIP 814

Query: 1034 TPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP--KGGPAT-PSLKGAPTPPAATPPSP 1090
                  P +P   P     P  +   P  +  SP     PA  P +  + T     P  P
Sbjct: 815  ADSPVVPVTPADDPIVPVTPADSSFVPVISADSPFVPVIPADGPVVVDSSTDVLVVPVFP 874

Query: 1091 KG---GPATPSPKGAPMPPAATPPSPKGGLATPPHK-GAPTTPAATPPSPKGGLATPPPK 1146
                  PA       P+ PA +P  P     TPP     P TP   P +P      P   
Sbjct: 875  VNCILVPAFADETVVPLNPADSPVIP----VTPPDDLVVPVTPTDCPVAPVTSADCPV-- 928

Query: 1147 GAPTTPAATPPSP----KGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1202
              P TPA +P  P     G +    P   P  P     SP   + + +P   P  P A+ 
Sbjct: 929  -VPVTPADSPADPVTAADGPVVPFTPADDPIVPVTPADSP---VVSVTPADGPVVPVASA 984

Query: 1203 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP---KGGPATPP 1259
             SP   +          TPA +P  P     +P     P T A  P SP     G   P 
Sbjct: 985  DSPFVPVTPADDPIVSVTPAESPAIPVTQADSPV---VPVTSADRPVSPVTTADGRIVPV 1041

Query: 1260 PKG----APTPPAATPPSLKGGLATP--PHKGAPNPAV-VTPPSPKGGPATS------PP 1306
                    P  PA TP S       P  P   A +P V VTPP     P TS      P 
Sbjct: 1042 TAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPV 1101

Query: 1307 KGA-----PTPPAATPPSPKGSPGTP----PPKGAPTPPAVT------PPSPKGTPTLPA 1351
              A     P   A  P +P  S   P     P  +P  P  T      P +P  +P L  
Sbjct: 1102 SSADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVLSV 1161

Query: 1352 TTPSSKGGPTTPS-SKEGPTPPAATP----SHKGGP-------------------AMTPP 1387
            T   S   P TP+ S   P PPA  P    S    P                    + P 
Sbjct: 1162 TLADSPVVPVTPADSPVIPVPPANGPVVPVSSADSPFVPVIPADGLVVLDSSTDVLVVPV 1221

Query: 1388 SPKRGPAIPSPKGDP------TSPAVIPLSPKKAPATPVTREGA----ATPSKGD--LTP 1435
            SP  G  +P    DP          VIP++P  +P  PVT   +     TP+     L  
Sbjct: 1222 SPTDGILVPDLADDPVVSVTIADSPVIPVTPADSPVVPVTSADSPVVPVTPADSPVILVT 1281

Query: 1436 PAVTPVSLKKA---------------PATSA--------PKGGPATPSSKGD-PTLPAVT 1471
            P    VS+  A               P TSA        P  GP  P +  D P +P   
Sbjct: 1282 PVGPVVSVTTADGPVVLVSTADSPVIPVTSADSPVVPVTPADGPVVPVTSADSPFVPVTP 1341

Query: 1472 PPSPKEPPAP-KQVATSSSPKKAPATP-APMGAPTLPAVIPSSPKEVPATPSSRRDPIAP 1529
               P  P  P      S +P ++PA P  P  +P +P     SP     T  SR  P+ P
Sbjct: 1342 ADDPIVPVTPADSPIVSVTPAESPAIPVTPADSPVVPVTSADSPLIPLTTAGSRVVPVTP 1401

Query: 1530 TATLLSKKTPATLAPKEALIPPAMTVP-SPKKTPAIP-TPKEAPATP-SSKEASSPPAVT 1586
            T   +   TPA              VP +P   P +P TP + P +P +S +    P  T
Sbjct: 1402 TGDPIVPVTPADTPGSPVTSADGPVVPVTPAGDPIVPVTPADTPGSPVTSADGPVVPVTT 1461

Query: 1587 PSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSS 1646
            P       SP +  + P VTS      P  PA +P  P      P    TP   PV P +
Sbjct: 1462 PDGPLVPVSPPDGPVVP-VTSADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVVPVT 1520

Query: 1647 LKDSPTSP-----------ASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPI 1695
              D P  P            S  C     +P  + GL A    T   +VLV P   +  +
Sbjct: 1521 PADIPVVPVTPANGPVIHVTSADCPFVPVIP--ADGLVALDSST---DVLVVPVSPTDGV 1575

Query: 1696 ITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDAS 1755
            +       P    + A SP I   P+  + +  P+ T+A  P++PV            A 
Sbjct: 1576 LVPDLADDPVVSVTIADSPVIPVTPA--DSTVVPV-TLADGPVVPVTSVDIPVVPVTPA- 1631

Query: 1756 HSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQ 1815
            + P  P+ P +    +   A      +   +   V   P+  + +P+ P+  P +P    
Sbjct: 1632 NGPVAPVTPVDDPVVSVNPADGSVVPVTSADCPVVPVTPADGLVVPVTPADSPIVPVTPA 1691

Query: 1816 FLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSV-LVNMPTPKSAGIPVPT 1874
              P       +SP  P+ PAD   ++P+   +  S G P  S     +P   +  +PVP 
Sbjct: 1692 DSPVVLVTSADSPVIPVTPAD-SPVVPVTSADTDSPGSPVTSADGPVVPVTSADSLPVPV 1750

Query: 1875 PSAKQPVTKNNKGSG 1889
              A  PV       G
Sbjct: 1751 TPADGPVVPVTSADG 1765



 Score =  259 bits (661), Expect = 2e-68
 Identities = 500/2173 (23%), Positives = 741/2173 (34%), Gaps = 363/2173 (16%)

Query: 10   PATEQELPQPQAETAVLPMSSALSVTAALGQPG-------PTLPPPCSPAPQQCPLSAAN 62
            PA    +P   A++ V+P++SA S    L   G       PT  P     P   P S   
Sbjct: 1361 PAESPAIPVTPADSPVVPVTSADSPLIPLTTAGSRVVPVTPTGDPIVPVTPADTPGSPVT 1420

Query: 63   QASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPN----LIGPPISPAALAL 118
             A     P T A  P+    P  + G+ +     P  P   P+     + PP  P     
Sbjct: 1421 SADGPVVPVTPAGDPIVPVTPADTPGSPVTSADGPVVPVTTPDGPLVPVSPPDGPVVPVT 1480

Query: 119  A------------SPMIA------PTLKGTPSSS-------APLALVALAPHS---VQKS 150
            +            SP I       P +  TP+ S       A + +V + P +   +  +
Sbjct: 1481 SADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVVPVTPADIPVVPVTPANGPVIHVT 1540

Query: 151  SAFPPNLLTSPPSVAVAESGSVITLSAPIAPSE----------PKTNLNKVPSEVVP-NP 199
            SA  P +   P    VA   S   L  P++P++          P  ++    S V+P  P
Sbjct: 1541 SADCPFVPVIPADGLVALDSSTDVLVVPVSPTDGVLVPDLADDPVVSVTIADSPVIPVTP 1600

Query: 200  KGTPSPPCIVSTVPYHCVT-------PMASIQSGVASL-PQTTPTTTLAIASPQVKDTTI 251
              +   P  ++  P   VT       P+      VA + P   P  ++  A   V   T 
Sbjct: 1601 ADSTVVPVTLADGPVVPVTSVDIPVVPVTPANGPVAPVTPVDDPVVSVNPADGSVVPVTS 1660

Query: 252  SSVLISPQNPGSLSLKGPV----SPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPI---- 303
            +   + P  P    L  PV    SP   ++ +   + +VTS+     P TP D P+    
Sbjct: 1661 ADCPVVPVTPAD-GLVVPVTPADSPIVPVTPADSPVVLVTSADSPVIPVTPADSPVVPVT 1719

Query: 304  ------------SLGSHLAPLHQSSFGSVQLLGQTGPSA---LSDPTVKTISVDHSSTGA 348
                        S    + P+  +    V +    GP      +D  V  +S        
Sbjct: 1720 SADTDSPGSPVTSADGPVVPVTSADSLPVPVTPADGPVVPVTSADGPVAPVSSADGPVVP 1779

Query: 349  SYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSL- 407
              P+   V+P   + +  VP T A  PVV      GP  I  +T + S  + V  +  L 
Sbjct: 1780 VTPADSPVVPVTTADDPTVPVTPADSPVVPVPPANGP--IVPVTSADSPFVPVIPADGLV 1837

Query: 408  ---SPTTSLILKSSPNATYHYPLVAQMPVSSV--GTTPLVVTNPCTIAAAPTTTFEVATC 462
               S T  L++  SP      P +A  PV SV    +P++   P T A +P      A  
Sbjct: 1838 VLDSSTDVLVVPVSPTDGILVPDLADDPVVSVTIADSPVI---PVTPADSPVVLVTPADG 1894

Query: 463  VSPPMSSGPISN-IEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSS 521
               P++S  + N + P +PA   + PV P +      T    P+ P       + ++  +
Sbjct: 1895 PVVPVTS--VDNPVVPVTPADNPVIPVTPVDDPVVPVTPADDPIVPVTSADSPIVSVTPA 1952

Query: 522  VLVKFP-TQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQA-------APKNSPSF 573
                FP T  D   +P +   +P  P      T  D  V+P++ A        P  SP+ 
Sbjct: 1953 DSPVFPVTPADSPVIPVASADSPLVPV-----TPADMVVVPVIPADGPVIPVTPAESPAI 2007

Query: 574  QST-SSSPEIPL-SPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDS 631
              T + SP +P+ S ++ +   +   P     PA S   P+       V+       P  
Sbjct: 2008 PVTPTDSPVVPVTSADSPVIPVTADSPFVPVTPADSPVIPVTPPDDL-VVPVTPIDCPVV 2066

Query: 632  AGPLLKSSLITPTVAAFPLESADPAG--VAPTTAKGTSTYTTT--------ASPFLEGTV 681
               L+   +++ T A  P++   PA   V P T   +     T         +P     V
Sbjct: 2067 PVTLVDCPVVSVTPANSPVDPVTPADGPVVPVTPADSPVIPVTPADDLIVPVTPADSLIV 2126

Query: 682  SLAPKNHPVKEGTLTTLPLVPTASENCPVAP-SPQNTCAPLATLVLAPEIPKS-VPSPSL 739
            S+ P + PV   T    P++  AS + PV P +P +T     T    P IP +   SP++
Sbjct: 2127 SVTPADSPVVPVTPADSPVISVASADSPVVPVTPADTVVVPVTPADGPVIPVTPAESPAI 2186

Query: 740  P--PAGTP--PGTKKVDGISHT----SALAPV--ASSPKECPTE-DSGASATASSKGTLT 788
            P  PA +P  P T   D +       S + PV  AS P    T  D+  S  AS+ G + 
Sbjct: 2187 PVTPADSPVVPVTPADDPVVPVTPADSPIVPVPPASDPVVPVTPADTPGSPVASADGPVV 2246

Query: 789  YLADSPSPLG---------VSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPEN 839
             +  + SPL          V V+P          + GP  P+     PV PV  +  P  
Sbjct: 2247 PVTSADSPLVPVTPGDSPVVPVTPADSPVFPVTSADGPVFPVTLADDPVFPVTPADDPIF 2306

Query: 840  SLSFQGSKDSPAT-THSPTPPSPKGAPTPSAVTPLSPKGVTLPP---------KETPTPS 889
             +S   S   P T  + P  P P   P   +V P++  G    P          ++ T  
Sbjct: 2307 PVSPADSPVVPVTPANIPVVPVP---PANGSVVPVTSAGSPFVPIIPADGLVVLDSSTDV 2363

Query: 890  VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASP-SPKGAPTPPAATPP 948
            +V L  P +G   P     P +S+T+S       TP     P  P +P   P  P  +  
Sbjct: 2364 LVVLVSPTDGIPVPDLADDPVVSVTTSDSPVIPVTPTDS--PVVPVAPADGPVVPVTSVD 2421

Query: 949  SPKGGPATPSPKWAPTPPAATPPSPKGGPATPS--------PKGAPTPPAATPPSPKGGP 1000
            SP   P TP+   +P  P  TP      PATP+        P   P  P  T   P    
Sbjct: 2422 SPVV-PVTPAD--SPVIPV-TPADSLVVPATPADDPVVSVTPADGPVVPVTTADIPVISV 2477

Query: 1001 ATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTP 1060
             +      P  PA     P  S  +   P   +  P   P  P  SP     P   P   
Sbjct: 2478 TSADSPVVPVTPADGLVVPVTSADSVVVPATPADCPLV-PVDPADSPIVLFTPYDNPVVS 2536

Query: 1061 AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG----APMPPAATPPSPKGG 1116
              +  SP   P TP+        +  P +P G P  P   G     P+ PA +   P   
Sbjct: 2537 VTSDDSPVF-PVTPA------DSSVVPVTPAGVPVVPVTPGDGPVVPVTPADSLVVPVTS 2589

Query: 1117 LATPPHKGAPTTPAATPPSPKGGLATP-PPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175
              +P     P      P SP   L  P  P  +P  P +   SP   +        P TP
Sbjct: 2590 ADSPVFPVTPADSPVFPVSPADDLVVPVTPGDSPVVPVSPADSPVVLVTPADGPVVPVTP 2649

Query: 1176 AATPPSPKGGLATPSPKGAP----------TTPAATPPSPKGGLATPSPKGAPTTPAATP 1225
            A  P  P     +P     P          T     P  P  G+  P     P  P    
Sbjct: 2650 ANGPVVPVTSADSPFVPVIPADGLVVLDSSTDVLVVPVFPTDGILVPDLADDPVVPVTPG 2709

Query: 1226 PSPKGGLATPSPKGAPTTPAA----TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP 1281
              P   +        P TPA      P +P  GP  P         +  P SL      P
Sbjct: 2710 DDPVVPVTPGDDPVIPVTPADDGPFVPVTPAVGPVVPD---LTADDSVVPDSLTDD---P 2763

Query: 1282 PHKGAPNPAVVTPPSPKGG--------PATSP--PKGAPTPPAATPPSPKGSPGTPPPKG 1331
                 P+  +V P + +          P T P     A   P  + P   G     PP  
Sbjct: 2764 VISVCPDDGLVVPDTVRDSDGPEVSVYPVTGPVVTDSAADCPVVSVPLTDGLVVLCPPDE 2823

Query: 1332 APTP-----------------PAVTPPSPKGTPTLPATTPSSKGGPTTPSS-KEGPTPPA 1373
             P                   P  + PS  G P +P  +  + G P    +    P P  
Sbjct: 2824 VPAVHDSVTNGLVVPDPVIDGPVFSNPSVDG-PIVPVASADNPGVPDPIRAFPVVPKPST 2882

Query: 1374 ATPSHKGGPAM-------------TPPSPKRGPAIPSPKGD------PTSPAVIPLSPKK 1414
             +P     PA               P +P  GP +P   GD      P +  ++ L+P  
Sbjct: 2883 FSPVVTSTPADWIDVIVTPADCADVPVNPVNGPVVPDLSGDCPVVPVPPTDDIVVLNPPD 2942

Query: 1415 AP----ATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV 1470
                  +TPVT     T    D     VTP +   AP T +         + G    P +
Sbjct: 2943 VVFAVVSTPVTDGPVVTDPATDGLMVPVTPANGSVAPVTLSEYPDVTVTPADGTVVSPTI 3002

Query: 1471 TPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSP----KEVPATPSSRRDP 1526
              P   +P A   V ++               PT   +I  +P      VP TP+    P
Sbjct: 3003 GGPVVPDPSADSSVVSN---------------PTTDGLIVPNPLLAGPVVPVTPTD--GP 3045

Query: 1527 IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT 1586
            +AP   +L+     T+ P +  +  A T       P  P P       S+     P    
Sbjct: 3046 LAP--VILADCPDVTVTPADGPVVCAFTTGG----PVFPDPTAEGLVVSNPTVDDPVVTN 3099

Query: 1587 PSTYKG--APSPKELLIPPAVTSPSP----------------------KEAPTPPAVTPP 1622
            PST KG  + +P +    P + +  P                        +P    V P 
Sbjct: 3100 PST-KGLVSATPADCADVPVIPADCPDVLVNLVNDSVVPDFTADWTVVSVSPPDDLVAPD 3158

Query: 1623 SPEKGPATPAP-----------------KGTPTSPPVTPSSLKDSPTSPASVTCKMGATV 1665
             P++ P    P                   TP   PV P  L D P    +VT      V
Sbjct: 3159 PPDEVPVVLVPITDGPVVPDLTTDGLVVSVTPAGAPVVPVFLTDCP--DVTVTPADSPVV 3216

Query: 1666 PQASKGLPAKKGPTALKEV----LVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPS 1721
            P      P+  GP     +    LV   P    ++      G        T  P+ PDPS
Sbjct: 3217 PD-----PSSDGPVVADSLDDDGLVPVTPADDSVVPDSPANG-LVVPDPTTDGPVAPDPS 3270

Query: 1722 AKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEK- 1780
                  GP+  V PA    V   S   A   D + +P   L   +SK   P+        
Sbjct: 3271 V----DGPVVPVTPADAPTV---SVTLADCPDVTVTPPDGLVVSDSKRGGPVVTGLSTND 3323

Query: 1781 ---VLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADE 1837
                    + + V+  P+    +P+ P+  P +P   +  P    L ++    P+ P+D+
Sbjct: 3324 PVITATPADFSDVTVTPADFEDVPVTPANCPDVPVNPE-SPVVSDLAVDFLVVPVVPSDD 3382

Query: 1838 ------DELLPLIPPEPISGGVPFQSVLVNM-----PTPKSAGIPV-PTPSAKQPVTKNN 1885
                   + +P++ P+PIS G+     + N      P+   + +PV P      PVT  +
Sbjct: 3383 LVVLEPPDKVPVV-PDPISNGLVVSDPITNNTAATDPSVDGSVVPVSPADGPVAPVTLAD 3441

Query: 1886 KGSGTESDSDESV 1898
                T + +D+SV
Sbjct: 3442 CPDVTITPADDSV 3454



 Score =  248 bits (632), Expect = 6e-65
 Identities = 538/2215 (24%), Positives = 758/2215 (34%), Gaps = 469/2215 (21%)

Query: 9    VPATEQE---LPQPQAETAVLPMSSALSVTAALGQP-GPTLPPPCSPAPQQCPLSAANQA 64
            VP T  +   +P   A+  V+P++SA    A +    GP +P      P   P+     A
Sbjct: 1738 VPVTSADSLPVPVTPADGPVVPVTSADGPVAPVSSADGPVVPV----TPADSPVVPVTTA 1793

Query: 65   SPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLP--------------NLIGPP 110
                 P T A +P+ VP P ++ G  +P+ T+ ++P F+P              +++  P
Sbjct: 1794 DDPTVPVTPADSPV-VPVPPAN-GPIVPV-TSADSP-FVPVIPADGLVVLDSSTDVLVVP 1849

Query: 111  ISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESG 170
            +SP        ++ P L   P  S  +A   + P +   S    P +L +P    V    
Sbjct: 1850 VSPT-----DGILVPDLADDPVVSVTIADSPVIPVTPADS----PVVLVTPADGPVVPVT 1900

Query: 171  SVITLSAPIAPSE-PKTNLNKVPSEVVP-NPKGTPSPPCIVSTVPYHCVTPMASIQSGVA 228
            SV     P+ P++ P   +  V   VVP  P   P  P   +  P   VTP  S    V 
Sbjct: 1901 SVDNPVVPVTPADNPVIPVTPVDDPVVPVTPADDPIVPVTSADSPIVSVTPADSPVFPVT 1960

Query: 229  SLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTS 288
              P  +P   +A A   +   T + +++ P  P      GPV P             VT 
Sbjct: 1961 --PADSPVIPVASADSPLVPVTPADMVVVPVIPAD----GPVIP-------------VTP 2001

Query: 289  SQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGA 348
            ++  A P TP D P+       P+  +    +       P     P V     D      
Sbjct: 2002 AESPAIPVTPTDSPV------VPVTSADSPVI-------PVTADSPFVPVTPADSPVIPV 2048

Query: 349  SYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFS-- 406
            + P    V+P  P    VVP T+   PVV  SV    S +  +T +    + V  + S  
Sbjct: 2049 TPPDDL-VVPVTPIDCPVVPVTLVDCPVV--SVTPANSPVDPVTPADGPVVPVTPADSPV 2105

Query: 407  --LSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVS 464
              ++P   LI+  +P  +    +V+  P  S    P+V   P     A +    VA+  S
Sbjct: 2106 IPVTPADDLIVPVTPADSL---IVSVTPADS----PVVPVTP-----ADSPVISVASADS 2153

Query: 465  PPMSSGPISNIE-PTSPAALVMAPVAPKEPSTQVATTLRIPVSP--PLPDPEDLKNLPSS 521
            P +   P   +  P +PA   + PV P E      T    PV P  P  DP        S
Sbjct: 2154 PVVPVTPADTVVVPVTPADGPVIPVTPAESPAIPVTPADSPVVPVTPADDPVVPVTPADS 2213

Query: 522  VLVKFPTQKD--LQTVPASLEGAPFSPAQAGL---TTKKDPTV------LPLVQAAPKNS 570
             +V  P   D  +   PA   G+P + A   +   T+   P V       P+V   P +S
Sbjct: 2214 PIVPVPPASDPVVPVTPADTPGSPVASADGPVVPVTSADSPLVPVTPGDSPVVPVTPADS 2273

Query: 571  PSFQSTSSS---------------------PEIPLSPEATLAKKSLGEPLPIGKPASSMT 609
            P F  TS+                      P  P+SP  +         +P+     +  
Sbjct: 2274 PVFPVTSADGPVFPVTLADDPVFPVTPADDPIFPVSPADSPVVPVTPANIPVVPVPPANG 2333

Query: 610  SPLGVNSSAS----VIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKG 665
            S + V S+ S    +I  D     DS+  +L   L++PT      + AD   V+ TT+  
Sbjct: 2334 SVVPVTSAGSPFVPIIPADGLVVLDSSTDVLVV-LVSPTDGIPVPDLADDPVVSVTTSDS 2392

Query: 666  -TSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATL 724
                 T T SP     V +AP + PV   T    P+VP    + PV P       P  +L
Sbjct: 2393 PVIPVTPTDSP----VVPVAPADGPVVPVTSVDSPVVPVTPADSPVIP-----VTPADSL 2443

Query: 725  VLAPEIPKSVPSPSLPPAG---TPPGTKKVDGISHTSALAPVA----------------- 764
            V+ P  P   P  S+ PA     P  T  +  IS TSA +PV                  
Sbjct: 2444 VV-PATPADDPVVSVTPADGPVVPVTTADIPVISVTSADSPVVPVTPADGLVVPVTSADS 2502

Query: 765  ----SSPKECP------TEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKG- 813
                ++P +CP       +      T      ++  +D      V+ +  +  P T  G 
Sbjct: 2503 VVVPATPADCPLVPVDPADSPIVLFTPYDNPVVSVTSDDSPVFPVTPADSSVVPVTPAGV 2562

Query: 814  SAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPA--TTHSPTPPSPKGAPTPSAVT 871
               P TP      PV+P ++  +P  S       DSP    T + +P  P  +P    V 
Sbjct: 2563 PVVPVTPGDGPVVPVTPADSLVVPVTSA------DSPVFPVTPADSPVFPV-SPADDLVV 2615

Query: 872  PLSPKGVTLPPKETPTPSVVNLPFPKEGPATPA-PKQAPALSMTSSSPKKARATPAPK-- 928
            P++P    + P  +P  S V L  P +GP  P  P   P + +TS+        PA    
Sbjct: 2616 PVTPGDSPVVPV-SPADSPVVLVTPADGPVVPVTPANGPVVPVTSADSPFVPVIPADGLV 2674

Query: 929  ---------GIPASPSPKGAPTPPAATPP----SPKGGPATP-SPKWAPTPPAA------ 968
                      +P  P+  G   P  A  P    +P   P  P +P   P  P        
Sbjct: 2675 VLDSSTDVLVVPVFPTD-GILVPDLADDPVVPVTPGDDPVVPVTPGDDPVIPVTPADDGP 2733

Query: 969  -TPPSPKGGPATPS--------PKGAPTPPAAT--PPSPKGGPATPSPKGAP-------T 1010
              P +P  GP  P         P      P  +  P      P T      P       T
Sbjct: 2734 FVPVTPAVGPVVPDLTADDSVVPDSLTDDPVISVCPDDGLVVPDTVRDSDGPEVSVYPVT 2793

Query: 1011 PPAVTPPSPKGSPAATPFPKGAST--PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPK 1068
             P VT  +      + P   G     PP   P           +P      P  + PS  
Sbjct: 2794 GPVVTDSAADCPVVSVPLTDGLVVLCPPDEVPAVHDSVTNGLVVPDPVIDGPVFSNPSVD 2853

Query: 1069 GGPATPSLK----GAPTPPAATPPSPKGGPATPSPKGAPMPP------------AATPPS 1112
            G P  P       G P P  A P  PK  P+T SP     P             A  P +
Sbjct: 2854 G-PIVPVASADNPGVPDPIRAFPVVPK--PSTFSPVVTSTPADWIDVIVTPADCADVPVN 2910

Query: 1113 PKGGLATPPHKG-APTTPAA--------TPPSPKGGLATPPPKGAP--TTPAA----TPP 1157
            P  G   P   G  P  P           PP     + + P    P  T PA      P 
Sbjct: 2911 PVNGPVVPDLSGDCPVVPVPPTDDIVVLNPPDVVFAVVSTPVTDGPVVTDPATDGLMVPV 2970

Query: 1158 SPKGGLATPP-----PKGAPTTPAATPPSPK-GGLATPSPKGA------PTTPAATPPSP 1205
            +P  G   P      P    T    T  SP  GG   P P         PTT     P+P
Sbjct: 2971 TPANGSVAPVTLSEYPDVTVTPADGTVVSPTIGGPVVPDPSADSSVVSNPTTDGLIVPNP 3030

Query: 1206 --KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGA 1263
               G +   +P   P  P      P     T +P   P   A T     GGP  P P   
Sbjct: 3031 LLAGPVVPVTPTDGPLAPVILADCPD---VTVTPADGPVVCAFTT----GGPVFPDPTAE 3083

Query: 1264 ------PT--PPAATPPSLKGGLATPPHKGAPNPAV---------------VTPPSPKGG 1300
                  PT   P  T PS KG ++  P   A  P +               V P      
Sbjct: 3084 GLVVSNPTVDDPVVTNPSTKGLVSATPADCADVPVIPADCPDVLVNLVNDSVVPDFTADW 3143

Query: 1301 P--ATSPPKG--APTPPAATP----PSPKGSPGTPP-----------PKGAPTPPAVTPP 1341
               + SPP    AP PP   P    P   G P  P            P GAP  P     
Sbjct: 3144 TVVSVSPPDDLVAPDPPDEVPVVLVPITDG-PVVPDLTTDGLVVSVTPAGAPVVPVFLTD 3202

Query: 1342 SPKGTPTLPATTP----SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPS 1397
             P  T T PA +P     S  GP    S +       TP+     ++ P SP  G  +P 
Sbjct: 3203 CPDVTVT-PADSPVVPDPSSDGPVVADSLDDDGLVPVTPADD---SVVPDSPANGLVVPD 3258

Query: 1398 PKGD-PTSP------AVIPLSPKKAPATPVTR----EGAATPSKGDLTP------PAVTP 1440
            P  D P +P       V+P++P  AP   VT     +   TP  G +        P VT 
Sbjct: 3259 PTTDGPVAPDPSVDGPVVPVTPADAPTVSVTLADCPDVTVTPPDGLVVSDSKRGGPVVTG 3318

Query: 1441 VSLKKAPATSAP---KGGPATPSSKGD-PTLPAVTPPSPKEPPAP--------------- 1481
            +S      T+ P        TP+   D P  PA  P  P  P +P               
Sbjct: 3319 LSTNDPVITATPADFSDVTVTPADFEDVPVTPANCPDVPVNPESPVVSDLAVDFLVVPVV 3378

Query: 1482 --KQVATSSSPKKAPATPAPMGAPTLPAVIPSSP--KEVPATPSSRRDPIAPTATLLSKK 1537
                +     P K P  P P+       ++ S P      AT  S    + P +      
Sbjct: 3379 PSDDLVVLEPPDKVPVVPDPISN----GLVVSDPITNNTAATDPSVDGSVVPVSPADGPV 3434

Query: 1538 TPATLA--PKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPS 1595
             P TLA  P   + P   +V S  K  A    ++ P T      +  P V P   K  P 
Sbjct: 3435 APVTLADCPDVTITPADDSVVSDSKIRA--EFEDVPVT-----IADCPNV-PVNPKSGPV 3486

Query: 1596 PKELLIP-PAVTSPSPKE--APTPPAVTPPSPE--------KGPATPAPKGTPTS----- 1639
              +L +  P V  P P +  AP PP   P  P+          P T  P  +  S     
Sbjct: 3487 VSDLAVDCPVVPIPPPDDLVAPEPPDEVPVVPDPITDSLVVSDPMTDGPVASDPSIDGIV 3546

Query: 1640 -PPVTPSSL----------------KDSPTSPASVTCKMGATVPQASKGLPAKKG-PT-- 1679
             P V+PS L                 D P +P  VT   G+ VP ++   P     PT  
Sbjct: 3547 VPVVSPSGLLVLDSVADVSILPDTSADVPVTP--VTLADGSVVPDSAPDCPVVPVLPTDG 3604

Query: 1680 -----ALKEVLVAPAPEST-PIITAPTRKGPQTKKSSATSPPICPD----PSAKNGSKGP 1729
                  L + +V P P    P++  PT  GP + K     P   PD    P  +      
Sbjct: 3605 FVVLDLLVDGVVVPNPADVGPVVPDPTTDGPDSIKDFPLVPDPWPDCPVVPVTRTDGPVV 3664

Query: 1730 LSTVAPAPLLPVQKDSSKTAKGKDASH------SPKGPLAP-PESKASTPLTAAAFEKVL 1782
            L + A   ++PV       A      +      +  GP+ P P +     L + A + ++
Sbjct: 3665 LDSSADGVVVPVTPGDDSVALVTPTDNLVVPDLTTDGPVVPDPSADGPVVLVSLADDLLV 3724

Query: 1783 PKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVL-----ESPSKPLAPADE 1837
            P P     +  P+     P+A  PV   P   +  PS+ GLV+     E P  P   AD+
Sbjct: 3725 PNP-PVKDTVVPNSVADNPVALDPVTDCPLVPE--PSANGLVVTDSLDEGPVVPDPSADD 3781

Query: 1838 DELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTES 1892
              +L                       P++ G+ VP  SA  PV  +    G+++
Sbjct: 3782 PVVL----------------------NPETNGLVVPDISANGPVVPDTPTDGSDA 3814



 Score =  209 bits (531), Expect = 3e-53
 Identities = 324/1275 (25%), Positives = 437/1275 (34%), Gaps = 271/1275 (21%)

Query: 785  GTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQ 844
            G +T L  SP  L ++V  QT       GS  P T  G+   PV P +   + ++S    
Sbjct: 15   GAVTLLPGSPVVLPITVVVQTD------GSVVPVTRAGSPFVPVIPADGLVVLDSS---- 64

Query: 845  GSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPK-EGPATP 903
                                 T   V P+ P    L P     P V   P      P TP
Sbjct: 65   ---------------------TDVLVVPVFPADGILVPDFADNPVVPVTPADDLVFPVTP 103

Query: 904  APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGA--PTPPAATPPSPKG---GPATP- 957
            A   +P + +TS+       TPA   +    S  G   P  PA +P  P     GP  P 
Sbjct: 104  A--DSPVIPVTSADDPVVPITPADNPVVPVTSANGPVIPVTPADSPVFPVASADGPVVPV 161

Query: 958  ----SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013
                SP + P  PA +P  P     +P     P   AA P +P  GP        P    
Sbjct: 162  TPADSPVF-PVTPADSPLFPVTPADSPLFPVTPADSAAIPVTPADGPVVHV---TPANGT 217

Query: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG--P 1071
            V P +P  SP  T     AST     P +P   P     P  +   P  +  SP     P
Sbjct: 218  VVPVTPADSPVVTV----ASTDSPVVPVTPADDPIVPVTPADSSFVPVISADSPFVPVIP 273

Query: 1072 AT-PSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPA 1130
            A  P +  + T     P  P      P+     +       S    + T      P TPA
Sbjct: 274  ADGPVVVDSSTDVLVVPVFPVNCILVPAFADETIXXXXXXXSLVVSVTTADDPIVPVTPA 333

Query: 1131 ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP-PPKGAPTTPAATPPSPKGGLATP 1189
             +P        +P     P      P  P  G   P  P  +P  P      P   +A+ 
Sbjct: 334  DSPVLSVTLADSPVVPVTPADSPFVPAIPADGPVVPVTPADSPVVPVTPADGPVVSVASA 393

Query: 1190 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1249
                 P TPA  P      + + +P  +P  P  +  SP   + T   +  P T A  P 
Sbjct: 394  DSPFVPVTPADDP------IVSVTPADSPVVPVTSADSPLIPVTTADGRVVPVTAAGDPI 447

Query: 1250 SPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA 1309
             P     TP   G+P   A  P          P   A  P V  P +P  GP        
Sbjct: 448  VPVTPADTP---GSPVTSADGP--------VVPVTSADIPLV--PVTPPDGPVV------ 488

Query: 1310 PTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS-SKEG 1368
            P   A  P +P  S   P          V P +P  +P +P TT      P TP+ S   
Sbjct: 489  PVTSADGPVAPVSSADGP----------VVPVTPADSPFIPVTTADDLIVPVTPADSPVL 538

Query: 1369 PTPPAATPSHKGGPA---MTPPSPKRGPAIPSPKGD----PTSPA---VIPLSPKKAPAT 1418
               PA +P+    PA   + P +P  GP +P    D    P  PA   V+P++P  +P  
Sbjct: 539  SVTPAESPAIPVTPADSPIVPVTPANGPVVPVTSADSPFVPVIPADGPVVPVTPADSPVV 598

Query: 1419 PVTREGAATPSKGDLTPPA--VTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPP--- 1473
            PVT   +   S      PA  VTP      P T  P  GP  P +  D     VTP    
Sbjct: 599  PVTPADSPVLSVTLADSPAVPVTPADSPVVPVT--PADGPVVPVASADSPFVPVTPADDP 656

Query: 1474 ----SPKEPPA--------PKQVATSSSPKKAPATPA-----PMGA------PTLPAVIP 1510
                +P E PA        P    TS+     P T A     P+ A      P  PA  P
Sbjct: 657  IVSVTPAESPAIPVTQADSPVVPVTSADRPVIPVTTADGRIVPVTAAGDPIVPVTPADTP 716

Query: 1511 SSPKE----------------VPATP--------SSRRDPIAPTATLLSKKTPAT----- 1541
             SP                  VP TP        +S   P+AP ++      P T     
Sbjct: 717  GSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGP 776

Query: 1542 LAPKEALIPPAMTV-PSPKKTPAIP-TPKEAPATPSSKEASSPPAVTPSTYKGAP-SPKE 1598
            +AP  +   P + V P+    PA+P T  ++P  P     S    VTP+     P +P +
Sbjct: 777  VAPVSSADGPVVPVTPADTNGPAVPVTSADSPFVPVIPADSPVVPVTPADDPIVPVTPAD 836

Query: 1599 LLIPPAVTSPSPKEAPTPPA--------------------------------VTPPSPEK 1626
                P +++ SP   P  PA                                V P +P  
Sbjct: 837  SSFVPVISADSP-FVPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFADETVVPLNPAD 895

Query: 1627 GPATPAPKGTPTSPPVTPSSLKDSPTSP-ASVTCKMGATVPQASKGLP--AKKGP----T 1679
             P  P    TP    V P +  D P +P  S  C +    P  S   P  A  GP    T
Sbjct: 896  SPVIPV---TPPDDLVVPVTPTDCPVAPVTSADCPVVPVTPADSPADPVTAADGPVVPFT 952

Query: 1680 ALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSP--PICPDPSAKNGSKGPLSTVAPA- 1736
               + +V   P  +P+++     GP    +SA SP  P+ P       +  P+ +V PA 
Sbjct: 953  PADDPIVPVTPADSPVVSVTPADGPVVPVASADSPFVPVTP-------ADDPIVSVTPAE 1005

Query: 1737 -PLLPVQKDSS---------------KTAKGK----DASHSPKGPLAPPESKAS------ 1770
             P +PV +  S                TA G+     A+  P  P+ P ++  S      
Sbjct: 1006 SPAIPVTQADSPVVPVTSADRPVSPVTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSAD 1065

Query: 1771 ---TPLTAA--AFEKVLPKPES------------ASVSAAPSPPVSLPLAPSPV------ 1807
                P+T+A   F  V P P+             A VS+A  P V +  A  PV      
Sbjct: 1066 GPVVPVTSADSPFVPVTP-PDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSA 1124

Query: 1808 --PTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTP 1865
              P +P      P  P    + P  P+ PAD   L   +   P+    P  S ++  P P
Sbjct: 1125 DGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVLSVTLADSPVVPVTPADSPVI--PVP 1182

Query: 1866 KSAGIPVPTPSAKQP 1880
             + G  VP  SA  P
Sbjct: 1183 PANGPVVPVSSADSP 1197


>gi|40548328 nascent-polypeptide-associated complex alpha
            polypeptide-like [Homo sapiens]
          Length = 215

 Score =  329 bits (843), Expect = 2e-89
 Identities = 177/214 (82%), Positives = 188/214 (87%)

Query: 1865 PKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDE 1924
            P  A   VP    + P ++   GSGT SDS ESVP +EEQDSTQ TTQ+A L AAAEIDE
Sbjct: 2    PGEATETVPATEQELPQSQAETGSGTASDSGESVPGIEEQDSTQTTTQKAWLVAAAEIDE 61

Query: 1925 EPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYI 1984
            EPV KAKQSRSEK+ARKAMSKLGL QVTGVTRVTI KSKNILFVITK DVYKSPASD YI
Sbjct: 62   EPVGKAKQSRSEKRARKAMSKLGLLQVTGVTRVTIWKSKNILFVITKLDVYKSPASDAYI 121

Query: 1985 VFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDI 2044
            VFGEAKI+DLSQQAQLAAAEKF+VQGEAV NIQENTQTPTVQEESEEEEVDETGVEVKD+
Sbjct: 122  VFGEAKIQDLSQQAQLAAAEKFRVQGEAVGNIQENTQTPTVQEESEEEEVDETGVEVKDV 181

Query: 2045 ELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 2078
            +LVMSQANVSRAKAVRALKNNSNDIVNAIMELT+
Sbjct: 182  KLVMSQANVSRAKAVRALKNNSNDIVNAIMELTV 215



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 22/23 (95%), Positives = 22/23 (95%)

Query: 1  MPGEATETVPATEQELPQPQAET 23
          MPGEATETVPATEQELPQ QAET
Sbjct: 1  MPGEATETVPATEQELPQSQAET 23


>gi|226437579 NAC alpha domain containing [Homo sapiens]
          Length = 1562

 Score =  327 bits (837), Expect = 1e-88
 Identities = 452/1602 (28%), Positives = 597/1602 (37%), Gaps = 269/1602 (16%)

Query: 625  SYAGPDSAGPLLKSSLITP---TVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTV 681
            ++A P   GP   S ++ P   +  A   E+  PA + P    G  T     SP    T 
Sbjct: 82   AWADPGEGGP---SPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTA 138

Query: 682  SLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPP 741
                +      G  +  P     S+     PSP        T    P  P       LP 
Sbjct: 139  LRDQEG-----GHASPDPPPELCSQGDLSVPSPPPDPDSFFT---PPSTPTKTTYALLPA 190

Query: 742  AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPS---PLG 798
             G     +  +       L    +SP        G S  +S   +L+ LA +     P G
Sbjct: 191  CGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSG 250

Query: 799  VSVSPQ-------------TKRPPTKKGSAGPDTPI-----GNLSSPVSPVEASFLPENS 840
              +SPQ             T  PP+ + S   D+       G+            +P   
Sbjct: 251  WGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAAL 310

Query: 841  LSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP 900
            L FQGS          TP SP+     +   P  P G      E  + S   L    +  
Sbjct: 311  LPFQGSLIFQVEAVEVTPLSPEEEEEEAVADP-DPGGDLAGEGEEDSTSASFLQSLSDLS 369

Query: 901  ATPAPKQAPAL----SMTSSSPKKARATPAPKGIPASPSPKGAPT---PPAATPPSPKGG 953
             T    +A A     S  SS    A    A      S  P    T             GG
Sbjct: 370  ITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGG 429

Query: 954  PATP------SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007
             A        +  WA    AA   S +G   +   +             +   AT +P  
Sbjct: 430  GAKGLQAQDGTVSWAVE--AAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHT 487

Query: 1008 APTPPAV-----TPPSPKGSPAATPFPKGASTPPAATP-PSPKGSPAATPLPKGAPTTPA 1061
                P +     T  +P+     T    G  +   A P PS +G         G  +  A
Sbjct: 488  LQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEIL----GQESVTA 543

Query: 1062 ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121
              LP+P+      SL   P  P       +GG   PS +         P   K  L  P 
Sbjct: 544  EKLPTPQ---EETSLTLCPDSPQNL--KEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQ 598

Query: 1122 HKGAPTTPAATPPSPKGGL---ATPPPKGAPTTPAATPPS----PKGGLATPPPKGAPTT 1174
                    A TPP P       + P P  A T  +         P+  + TPP     T 
Sbjct: 599  DS------AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTE 652

Query: 1175 PAATP-PSPKGGLATPSPKGAPTTP---AATPPSPKGGL---ATPSPKGAPTTPAATPPS 1227
             ++ P P     L +   +   T P   A TPP P       + P P  A T  +     
Sbjct: 653  LSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQ---Q 709

Query: 1228 PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP---PSLKGGLATPPHK 1284
             + GL  P         A TPP P           AP P AA        + GL  P   
Sbjct: 710  AEEGLTLPQDS------AMTPPLPLQDTDL---SSAPKPVAAATLVSQQAEEGLTLP--- 757

Query: 1285 GAPNPAVVTPPSPKGGPATSPPKGAPTP-PAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343
                 + +TPP P      S    AP P  AAT  S +   G   P+ +    A+TPP P
Sbjct: 758  ---QDSAMTPPLPLQDTDLS---SAPKPVAAATIVSQQAEEGLTLPQDS----AMTPPLP 807

Query: 1344 -KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402
             + T    A  P +     +  ++EG T P  +       AMTPP P +   + S     
Sbjct: 808  LQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS-------AMTPPLPLQDTDLSS----- 855

Query: 1403 TSPAVIPLSPKK-APATPVTR---EGAATPSKGDLTPPAVTPVSLKKAPATSAPK----G 1454
                    +PK  A ATPV++   EG   P    +TPP    + L+    +SAPK     
Sbjct: 856  --------APKPVAAATPVSQQAEEGLTLPQDSAMTPP----LPLQDTDLSSAPKPVAAA 903

Query: 1455 GPATPSSKGDPTLP---AVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA-----PTLP 1506
             P +  ++   TLP   A+T P P +   P    TS     A ATP  + A     P   
Sbjct: 904  TPVSQQAEEGLTLPQDSAMTAPLPLQDTGP----TSGPEPLAVATPQTLQAEAGCAPGTE 959

Query: 1507 AVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP-PAMTVPSP------- 1558
             V   + +EV      R  P    A L +   PA L   +   P PA    +P       
Sbjct: 960  PVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDA 1019

Query: 1559 -----KKTPAIPTPK--------EAPATPSSKEASSPPAVTPSTYKGAPSPKELL----- 1600
                  +  ++P P         EA + P  +      A T    K     KE L     
Sbjct: 1020 DSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQ 1079

Query: 1601 ----IPPAVTSPSPKEA--------PTPPAVTPPSPEKGPATPAPK-----GTPTSPPVT 1643
                + P      P+ A          PPA  P   +    +PA +     G  T  P  
Sbjct: 1080 QEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTL 1139

Query: 1644 PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTA---------------LKEVLVAP 1688
            PS++    +  +     +GA V    +G P    PT+               +++    P
Sbjct: 1140 PSAVATEASLDSCPESSVGA-VSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVP 1198

Query: 1689 APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG----PLSTVAPAPLLPVQKD 1744
            +   TP++  P     + + S+    P+ PDPSA     G    PL   AP      Q+D
Sbjct: 1199 SVLGTPLLQPPENLA-KGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQED 1257

Query: 1745 SSKTAKGKDASHSPKGPLA-PPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLA 1803
            S +          P G L  PP      P  AA      P      VS +P  P+  P  
Sbjct: 1258 SVE-------DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSP-- 1308

Query: 1804 PSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMP 1863
               V ++  K   L   P   +  PS P +PA                           P
Sbjct: 1309 --KVASMDAKDLALQILPPCQVPPPSGPQSPAG--------------------------P 1340

Query: 1864 TPKSAGIPVPTPSAKQPVTKNNKGSGTESDSD-ESVPELEEQDSTQATTQQAQLAAAAEI 1922
               SA        + +  +    GSG  SDS  ES  EL+EQD     T Q    A A  
Sbjct: 1341 QGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGG 1400

Query: 1923 DEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDT 1982
             EE ++KAKQSRSEKKARKAMSKLGLRQ+ GVTR+TI+KSKNILFVI KPDV+KSPASDT
Sbjct: 1401 SEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDT 1460

Query: 1983 YIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTV------QEESEEEEVDE 2036
            Y+VFGEAKIEDLSQQ   AAAEKFKV  E  + + E+   P V      +EE EEEEVDE
Sbjct: 1461 YVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDE 1520

Query: 2037 TGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 2078
             G+E++DIELVM+QANVSRAKAVRAL++N +DIVNAIMELTM
Sbjct: 1521 AGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM 1562



 Score = 99.0 bits (245), Expect = 4e-20
 Identities = 207/892 (23%), Positives = 311/892 (34%), Gaps = 154/892 (17%)

Query: 224  QSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQN---PGSLSLKGPVSPPAALSL-S 279
            Q G++ +      T   + +PQ ++T+++    SPQN    G L L     P AA ++  
Sbjct: 529  QEGISEILGQESVTAEKLPTPQ-EETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVP 587

Query: 280  TQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTI 339
             Q+   +T  Q +A   TPP           PL  +   S          A       TI
Sbjct: 588  RQAKEDLTLPQDSA--MTPP----------LPLQDTDLSS----------APKPVAAATI 625

Query: 340  SVDHSSTGASYPSQRSVIPPLPSRNEVV---PATVAAFPVVAPSVDKGPSTISSITCSPS 396
                +  G + P    + PPLP ++  +   P  VAA  +V+   ++G +       +P 
Sbjct: 626  VSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPP 685

Query: 397  GSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQ-------MPVSSVGTTPLVVTN---- 445
                        P     L S+P       LV+Q       +P  S  T PL + +    
Sbjct: 686  -----------LPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLS 734

Query: 446  --PCTIAAAPTTTFEVATCVSPPMSSG-----PISNIEPTS-PAALVMAPVAPKEPSTQV 497
              P  +AAA   + +    ++ P  S      P+ + + +S P  +  A +  ++    +
Sbjct: 735  SAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGL 794

Query: 498  ATTLRIPVSPPLP-DPEDLKNLPSSVLVKFPTQKDLQ---TVPASLEGAPFSPAQ-AGLT 552
                   ++PPLP    DL + P  V       +  +   T+P      P  P Q   L+
Sbjct: 795  TLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLS 854

Query: 553  TKKDPTVL--PLVQAAPKNSPSFQSTSSSPEIPLSP-EATLAKKSLGEPLPIGKPA---- 605
            +   P     P+ Q A +     Q ++ +P +PL   + + A K +    P+ + A    
Sbjct: 855  SAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGL 914

Query: 606  -----SSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAP 660
                 S+MT+PL +  +          GP S GP        P   A P      AG AP
Sbjct: 915  TLPQDSAMTAPLPLQDT----------GPTS-GP-------EPLAVATPQTLQAEAGCAP 956

Query: 661  TTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAP 720
                GT    T A    E   +L P+  P  E     LP VP  +    V        A 
Sbjct: 957  ----GTEPVATMAQQ--EVGEALGPR--PAPEEKNAALPTVPEPAALDQVQQDDPQPAAE 1008

Query: 721  LATLVLAPEIPKS---VPSPSLPPAGTPPGTKKVDGIS------------HTSALAPVAS 765
              T   A E   S   + + SLP   +  G +  + +S            HT   A   S
Sbjct: 1009 AGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDS 1068

Query: 766  SPKEC----PTEDSGASATASSKGTLTYLA------DSPSPLGVSVSPQTKRPPTK--KG 813
              KE       ++ G    A   G  + L       D+P      VS      P +  +G
Sbjct: 1069 PQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERG 1128

Query: 814  SAGPDTPIGNLSSPVSPVEASF--LPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT 871
             +G  TP   L S V+  EAS    PE+S+    S D       P  P+P  APT     
Sbjct: 1129 LSGKSTPEPTLPSAVA-TEASLDSCPESSVGAVSSLDRGC----PDAPAPTSAPTSQQPE 1183

Query: 872  PLSPKGVTLPPKETPTPSVVNLPFPKEG-----PATPAPKQAPALSMTSSSPKKARATPA 926
            P+   G    P E P+     L  P E      P+TP  +    L    S+P        
Sbjct: 1184 PVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRP---LGPDPSAPGTLAGAAL 1240

Query: 927  PKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAP 986
            P   P +P     P   +     P G    P P+      A   P+      T  P G  
Sbjct: 1241 PPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQ------AGVQPAAAAVSGTTQPLGTG 1294

Query: 987  TPPAATPPSPKGGPATPSPKGAPTPPAVTPP---SPKGSPAATPFPKGASTP 1035
               + +P SP   P   S         + PP    P   P +   P+G S P
Sbjct: 1295 PRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAP 1346



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 228/969 (23%), Positives = 330/969 (34%), Gaps = 140/969 (14%)

Query: 435  SVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPS 494
            ++G        P T+  AP    EVAT V+P        +      AA+ M P   +E  
Sbjct: 474  ALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAM-PQPSQEGI 532

Query: 495  TQVATTLRIPVSPPLPDPEDLKNL----PSSVLVKFPTQKDLQTVPASLEGAPFSPAQAG 550
            +++     +  +  LP P++  +L     S   +K     DL +    +  A   P QA 
Sbjct: 533  SEILGQESV-TAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQA- 590

Query: 551  LTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTS 610
                K+   LP   A     P   +  SS   P++  AT+  +   E L + +  S MT 
Sbjct: 591  ----KEDLTLPQDSAMTPPLPLQDTDLSSAPKPVA-AATIVSQQAEEGLTLPQD-SVMTP 644

Query: 611  PLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAA----FPLESADPAGVAPTTAKGT 666
            PL +  +         A         +  L  P  +A     PL+  D +      A   
Sbjct: 645  PLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA-- 702

Query: 667  STYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVL 726
                T  S   E  ++L     P        LPL  T   + P          P+A   L
Sbjct: 703  ---ATLVSQQAEEGLTL-----PQDSAMTPPLPLQDTDLSSAP---------KPVAAATL 745

Query: 727  APEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGT 786
              +  +   +     A TPP   +   +S  SA  PVA++       + G +    S  T
Sbjct: 746  VSQQAEEGLTLPQDSAMTPPLPLQDTDLS--SAPKPVAAATIVSQQAEEGLTLPQDSAMT 803

Query: 787  L------TYLADSPSPLGVS--VSPQTKRPPTKKGSAGPDTPI----GNLSSPVSPVEAS 834
                   T L+ +P P+  +  VS Q +   T    +    P+     +LSS   PV A+
Sbjct: 804  PPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAA 863

Query: 835  FLPENSLSFQG---SKDSPATTHSP-------TPPSPKGAPTPSAVTPLSPKGVTLPPKE 884
              P +  + +G    +DS  T   P       + P P  A TP  V+  + +G+TLP   
Sbjct: 864  -TPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATP--VSQQAEEGLTLPQDS 920

Query: 885  TPT-PSVVNLPFPKEGP-----ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKG 938
              T P  +    P  GP     ATP   QA A     + P    AT A + +  +  P+ 
Sbjct: 921  AMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPV---ATMAQQEVGEALGPRP 977

Query: 939  APTPP-AATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK 997
            AP    AA P  P+              PAA     +  P   +  G P        S  
Sbjct: 978  APEEKNAALPTVPE--------------PAALDQVQQDDPQPAAEAGTPWAAQEDADSTL 1023

Query: 998  GGPATPSPK-----GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052
            G  A   P+     G     A++ P  +    A      A T   A P SP+        
Sbjct: 1024 GMEALSLPEPASGAGEEIAEALSRPGREACLEAR-----AHTGDGAKPDSPQKETLEVEN 1078

Query: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAP-TPPAATPPSPKGGPATPSPKGAPMPPAATPP 1111
             +     P A    P+   A    +  P  PPAA P   +    +P+ +   +   +TP 
Sbjct: 1079 QQEGGLKPLAQEHGPRS--ALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPE 1136

Query: 1112 SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT------PPSPKGGL-A 1164
                   T P   A      + P    G  +   +G P  PA T       P P  GL +
Sbjct: 1137 ------PTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGS 1190

Query: 1165 TPPPKGAPT---TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1221
               P   P+   TP   PP     LA    KG P+TP   P  P      PS  G     
Sbjct: 1191 VEQPHEVPSVLGTPLLQPPE---NLA----KGQPSTPVDRPLGP-----DPSAPGTLAGA 1238

Query: 1222 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLAT- 1280
            A  P  P      P     P   +     P G    PPP+    P AA        L T 
Sbjct: 1239 ALPPLEP----PAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTG 1294

Query: 1281 -----PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP 1335
                  PH    +P V +  +        PP     PP + P SP G  G   P+     
Sbjct: 1295 PRVSLSPHSPLLSPKVASMDAKDLALQILPP--CQVPPPSGPQSPAGPQGLSAPEQQEDE 1352

Query: 1336 PAVTPPSPK 1344
             ++   SP+
Sbjct: 1353 DSLEEDSPR 1361



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 198/966 (20%), Positives = 328/966 (33%), Gaps = 134/966 (13%)

Query: 993  PPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052
            P + + GP T     A     +     +   A TP P   +     + P  +  P     
Sbjct: 13   PEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASW 72

Query: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112
              G    P+A     +GGP+   L             P+G  +      AP+ PA   P 
Sbjct: 73   DAGPGGAPSAWADPGEGGPSPMLL-------------PEGLSSQALSTEAPL-PATLEPR 118

Query: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPP------KGAPTTPAATPPSPKGGLATP 1166
               G  T     +P          +GG A+P P      +G  + P  +PP       TP
Sbjct: 119  IVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVP--SPPPDPDSFFTP 176

Query: 1167 PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP-SPKGGLATPSPKGAPTTPAATP 1225
            P     TT A  P     G A  S          +PP SP G   T       ++P+ + 
Sbjct: 177  PSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSL 236

Query: 1226 P--SPKGGLATPSPKGAPTTPAATPPSPKGGPATP---PPKGAPTPPAATPPSLKGGLAT 1280
               +P  GL  PS  G          SP+G         P G P PP++         ++
Sbjct: 237  SLLAPAEGLDFPSGWGL---------SPQGSMVDERELHPAGTPEPPSSESSLSADSSSS 287

Query: 1281 PPHKG--------APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA 1332
               +G        A +P +     P  G      +     P +     + +   P P G 
Sbjct: 288  WGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGG- 346

Query: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392
                        G     +T+ S     +  S  EG     A        +    S    
Sbjct: 347  ---------DLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYA 397

Query: 1393 PAIPSP--KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATS 1450
             A       G+P + A +        +   T E +   +KG          +++ AP TS
Sbjct: 398  EADDERLYSGEPHAQATL-----LQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTS 452

Query: 1451 APKGGPATPSSK------------GDPTLPAVTPPSPKEPPAPK-QVATSSSPKKA-PAT 1496
              +G   +   +            G  +   VTP + +  P  + +VAT  +P+     T
Sbjct: 453  -DRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEET 511

Query: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL---APKEALIPPAM 1553
             +  G  +    +P   +E  +    +    A       ++T  TL   +P+       +
Sbjct: 512  DSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGL 571

Query: 1554 TVPSPKKTPAIPT------------PKEAPATP-----SSKEASSPPAVTPSTYKGAPSP 1596
             +PS +K  A  T            P+++  TP      +  +S+P  V  +T     + 
Sbjct: 572  DLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAE 631

Query: 1597 KELLIP--PAVTSPSP------KEAPTPPA---VTPPSPEKGPATPAPKGTPTSPPVTPS 1645
            + L +P    +T P P        AP P A   +     E+G   P         P+  +
Sbjct: 632  EGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDT 691

Query: 1646 SLKDSPTSPASVT-----CKMGATVPQASKGLPAKKGPTALKEVLVAPAPE---STPIIT 1697
             L  +P   A+ T      + G T+PQ S   P    P  L++  ++ AP+   +  +++
Sbjct: 692  DLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTP----PLPLQDTDLSSAPKPVAAATLVS 747

Query: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757
                +G    + SA +PP+    +  + +  P   VA A ++  Q +   T   +D++ +
Sbjct: 748  QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP---VAAATIVSQQAEEGLTLP-QDSAMT 803

Query: 1758 PKGPL-------APPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTL 1810
            P  PL       AP    A+T ++  A E +    +SA     P     L  AP PV   
Sbjct: 804  PPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAA 863

Query: 1811 PPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPF-QSVLVNMPTPKSAG 1869
             P  Q       L  +S   P  P  + +L     P+P++   P  Q     +  P+ + 
Sbjct: 864  TPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSS--APKPVAAATPVSQQAEEGLTLPQDSA 921

Query: 1870 IPVPTP 1875
            +  P P
Sbjct: 922  MTAPLP 927



 Score = 79.0 bits (193), Expect = 5e-14
 Identities = 222/1032 (21%), Positives = 352/1032 (34%), Gaps = 210/1032 (20%)

Query: 4    EATETV-PATEQELPQPQAETA--VLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSA 60
            E+T TV P T Q  P  Q E A  V P +      +  GQ                   +
Sbjct: 478  ESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQ------------------ES 519

Query: 61   ANQASPFPSPSTIAS-------TPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISP 113
            A  A P PS   I+        T  ++P PQ  +   L     P++P  L    G  +  
Sbjct: 520  AAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTL----CPDSPQNLKEEGGLDL-- 573

Query: 114  AALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVI 173
                             PS   P+A   + P   ++    P +   +PP + + ++    
Sbjct: 574  -----------------PSGRKPVAAATIVPRQAKEDLTLPQDSAMTPP-LPLQDT---- 611

Query: 174  TLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQT 233
             LS+   P    T +++   E +  P+ +   P            P+    + ++S P+ 
Sbjct: 612  DLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTP------------PLPLQDTELSSAPKP 659

Query: 234  TPTTTLAIASPQVKDTTISSVLISPQNP-GSLSLKGPVSPPAALSL-STQSLPVVTSSQK 291
                TL     +   T      ++P  P     L     P AA +L S Q+   +T  Q 
Sbjct: 660  VAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQD 719

Query: 292  TAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYP 351
            +A   TPP           PL  +             SA       T+    +  G + P
Sbjct: 720  SA--MTPP----------LPLQDTDLS----------SAPKPVAAATLVSQQAEEGLTLP 757

Query: 352  SQRSVIPPLPSRN---EVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLS 408
               ++ PPLP ++      P  VAA  +V+   ++G              L +    +++
Sbjct: 758  QDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG--------------LTLPQDSAMT 803

Query: 409  PTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMS 468
            P                PL  Q    S    P+      +  A    T    + ++PP+ 
Sbjct: 804  P----------------PLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPL- 846

Query: 469  SGPISNIEPTSPAALVMAPVAPKEP-STQVATTLRIP----VSPPLP-DPEDLKNLPSSV 522
              P+ + + +S       PVA   P S Q    L +P    ++PPLP    DL + P  V
Sbjct: 847  --PLQDTDLSS----APKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 900

Query: 523  LVKFPTQKDLQ---TVPA-SLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSS 578
                P  +  +   T+P  S   AP      G T+  +    PL  A P+   +    + 
Sbjct: 901  AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPE----PLAVATPQTLQAEAGCAP 956

Query: 579  SPEIPLSPEATLAKKSLGE-----PLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAG 633
              E    P AT+A++ +GE     P P  K A+  T P    +   V + D     ++  
Sbjct: 957  GTE----PVATMAQQEVGEALGPRPAPEEKNAALPTVPEPA-ALDQVQQDDPQPAAEAGT 1011

Query: 634  PLLKSSLITPTVAAFPLESADPAGVA------PTTAKGTSTYTTTASPFLEGTVSLAPKN 687
            P         T+    L   +PA  A        +  G        +   +G    +P+ 
Sbjct: 1012 PWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQK 1071

Query: 688  HPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPS--PSLPPAGTP 745
              ++        L P A E+            P + L  A E+P + P+  P +  A   
Sbjct: 1072 ETLEVENQQEGGLKPLAQEH-----------GPRSALGGAREVPDAPPAACPEVSQARLL 1120

Query: 746  PGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYL----ADSPSPLGVSV 801
               ++  G+S  S   P  + P    TE S  S   SS G ++ L     D+P+P   + 
Sbjct: 1121 SPAREERGLSGKS--TPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAP---TS 1175

Query: 802  SPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSP 861
            +P +++P    G    + P    S   +P+     PEN    Q S          TP   
Sbjct: 1176 APTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQP--PENLAKGQPS----------TPVDR 1223

Query: 862  KGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKA 921
               P PSA  P +  G  LPP E P P +       + P   + +           P +A
Sbjct: 1224 PLGPDPSA--PGTLAGAALPPLEPPAPCLC------QDPQEDSVEDEEPPGSLGLPPPQA 1275

Query: 922  RATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP-----TPPAATPPSPKGG 976
               PA   +  +  P G     + +P SP   P   S           PP   PP P G 
Sbjct: 1276 GVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPP-PSGP 1334

Query: 977  PATPSPKGAPTP 988
             +   P+G   P
Sbjct: 1335 QSPAGPQGLSAP 1346



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 68/283 (24%), Positives = 93/283 (32%), Gaps = 42/283 (14%)

Query: 980  PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS------ 1033
            P P+   +  AA   +  GG         P P  +        P A P P+GAS      
Sbjct: 18   PGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASWDAGPG 77

Query: 1034 TPPAATPPSPKGSPAATPLPKGAPT--------TPAATLPSPKGGPATPSLKGAPTPPAA 1085
              P+A     +G P+   LP+G  +         PA   P    G  T     +P     
Sbjct: 78   GAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAART 137

Query: 1086 TPPSPKGGPATPSPKGAPMPP---------AATPPSPKGGLATPPHKGAPTTPAATPP-S 1135
                 +GG A+P P     PP           +PP       TPP     TT A  P   
Sbjct: 138  ALRDQEGGHASPDP-----PPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACG 192

Query: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP--SPKGGLATPSPKG 1193
            P G       +       + P SP G   T       ++P+ +    +P  GL  PS  G
Sbjct: 193  PHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWG 252

Query: 1194 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1236
                      SP+G +          TP   PPS +  L+  S
Sbjct: 253  L---------SPQGSMVDERELHPAGTP--EPPSSESSLSADS 284



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 61/240 (25%), Positives = 83/240 (34%), Gaps = 42/240 (17%)

Query: 902  TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT---PPAATPPSPKGGPATPS 958
            TP P     L++T   P K  A P P+G      P GAP+    P    PSP   P   S
Sbjct: 46   TPGPSH---LALTFL-PSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLS 101

Query: 959  PKWAPTP---PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT 1015
             +   T    PA   P    G  T     +P          +GG A+P P     PP + 
Sbjct: 102  SQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDP-----PPELC 156

Query: 1016 PPSPKGSPAATPFPKGASTPPAA-TPPSPKGSPAATP--------------LPKGAPTTP 1060
                   P+  P P    TPP+  T  +    PA  P              L    P +P
Sbjct: 157  SQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASP 216

Query: 1061 AATLPSPKGG--PATPSLKGAPTPPAATPPSPKGGPATPS----------PKGAPMPPAA 1108
            + +  +  G    ++PS   +   PA     P G   +P           P G P PP++
Sbjct: 217  SGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSS 276


>gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1562

 Score =  327 bits (837), Expect = 1e-88
 Identities = 452/1602 (28%), Positives = 597/1602 (37%), Gaps = 269/1602 (16%)

Query: 625  SYAGPDSAGPLLKSSLITP---TVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTV 681
            ++A P   GP   S ++ P   +  A   E+  PA + P    G  T     SP    T 
Sbjct: 82   AWADPGEGGP---SPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTA 138

Query: 682  SLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPP 741
                +      G  +  P     S+     PSP        T    P  P       LP 
Sbjct: 139  LRDQEG-----GHASPDPPPELCSQGDLSVPSPPPDPDSFFT---PPSTPTKTTYALLPA 190

Query: 742  AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPS---PLG 798
             G     +  +       L    +SP        G S  +S   +L+ LA +     P G
Sbjct: 191  CGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSG 250

Query: 799  VSVSPQ-------------TKRPPTKKGSAGPDTPI-----GNLSSPVSPVEASFLPENS 840
              +SPQ             T  PP+ + S   D+       G+            +P   
Sbjct: 251  WGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAAL 310

Query: 841  LSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP 900
            L FQGS          TP SP+     +   P  P G      E  + S   L    +  
Sbjct: 311  LPFQGSLIFQVEAVEVTPLSPEEEEEEAVADP-DPGGDLAGEGEEDSTSASFLQSLSDLS 369

Query: 901  ATPAPKQAPAL----SMTSSSPKKARATPAPKGIPASPSPKGAPT---PPAATPPSPKGG 953
             T    +A A     S  SS    A    A      S  P    T             GG
Sbjct: 370  ITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGG 429

Query: 954  PATP------SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007
             A        +  WA    AA   S +G   +   +             +   AT +P  
Sbjct: 430  GAKGLQAQDGTVSWAVE--AAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHT 487

Query: 1008 APTPPAV-----TPPSPKGSPAATPFPKGASTPPAATP-PSPKGSPAATPLPKGAPTTPA 1061
                P +     T  +P+     T    G  +   A P PS +G         G  +  A
Sbjct: 488  LQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEIL----GQESVTA 543

Query: 1062 ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121
              LP+P+      SL   P  P       +GG   PS +         P   K  L  P 
Sbjct: 544  EKLPTPQ---EETSLTLCPDSPQNL--KEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQ 598

Query: 1122 HKGAPTTPAATPPSPKGGL---ATPPPKGAPTTPAATPPS----PKGGLATPPPKGAPTT 1174
                    A TPP P       + P P  A T  +         P+  + TPP     T 
Sbjct: 599  DS------AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTE 652

Query: 1175 PAATP-PSPKGGLATPSPKGAPTTP---AATPPSPKGGL---ATPSPKGAPTTPAATPPS 1227
             ++ P P     L +   +   T P   A TPP P       + P P  A T  +     
Sbjct: 653  LSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQ---Q 709

Query: 1228 PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP---PSLKGGLATPPHK 1284
             + GL  P         A TPP P           AP P AA        + GL  P   
Sbjct: 710  AEEGLTLPQDS------AMTPPLPLQDTDL---SSAPKPVAAATLVSQQAEEGLTLP--- 757

Query: 1285 GAPNPAVVTPPSPKGGPATSPPKGAPTP-PAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343
                 + +TPP P      S    AP P  AAT  S +   G   P+ +    A+TPP P
Sbjct: 758  ---QDSAMTPPLPLQDTDLS---SAPKPVAAATIVSQQAEEGLTLPQDS----AMTPPLP 807

Query: 1344 -KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402
             + T    A  P +     +  ++EG T P  +       AMTPP P +   + S     
Sbjct: 808  LQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS-------AMTPPLPLQDTDLSS----- 855

Query: 1403 TSPAVIPLSPKK-APATPVTR---EGAATPSKGDLTPPAVTPVSLKKAPATSAPK----G 1454
                    +PK  A ATPV++   EG   P    +TPP    + L+    +SAPK     
Sbjct: 856  --------APKPVAAATPVSQQAEEGLTLPQDSAMTPP----LPLQDTDLSSAPKPVAAA 903

Query: 1455 GPATPSSKGDPTLP---AVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA-----PTLP 1506
             P +  ++   TLP   A+T P P +   P    TS     A ATP  + A     P   
Sbjct: 904  TPVSQQAEEGLTLPQDSAMTAPLPLQDTGP----TSGPEPLAVATPQTLQAEAGCAPGTE 959

Query: 1507 AVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP-PAMTVPSP------- 1558
             V   + +EV      R  P    A L +   PA L   +   P PA    +P       
Sbjct: 960  PVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDA 1019

Query: 1559 -----KKTPAIPTPK--------EAPATPSSKEASSPPAVTPSTYKGAPSPKELL----- 1600
                  +  ++P P         EA + P  +      A T    K     KE L     
Sbjct: 1020 DSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQ 1079

Query: 1601 ----IPPAVTSPSPKEA--------PTPPAVTPPSPEKGPATPAPK-----GTPTSPPVT 1643
                + P      P+ A          PPA  P   +    +PA +     G  T  P  
Sbjct: 1080 QEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTL 1139

Query: 1644 PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTA---------------LKEVLVAP 1688
            PS++    +  +     +GA V    +G P    PT+               +++    P
Sbjct: 1140 PSAVATEASLDSCPESSVGA-VSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVP 1198

Query: 1689 APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG----PLSTVAPAPLLPVQKD 1744
            +   TP++  P     + + S+    P+ PDPSA     G    PL   AP      Q+D
Sbjct: 1199 SVLGTPLLQPPENLA-KGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQED 1257

Query: 1745 SSKTAKGKDASHSPKGPLA-PPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLA 1803
            S +          P G L  PP      P  AA      P      VS +P  P+  P  
Sbjct: 1258 SVE-------DEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSP-- 1308

Query: 1804 PSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMP 1863
               V ++  K   L   P   +  PS P +PA                           P
Sbjct: 1309 --KVASMDAKDLALQILPPCQVPPPSGPQSPAG--------------------------P 1340

Query: 1864 TPKSAGIPVPTPSAKQPVTKNNKGSGTESDSD-ESVPELEEQDSTQATTQQAQLAAAAEI 1922
               SA        + +  +    GSG  SDS  ES  EL+EQD     T Q    A A  
Sbjct: 1341 QGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGG 1400

Query: 1923 DEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDT 1982
             EE ++KAKQSRSEKKARKAMSKLGLRQ+ GVTR+TI+KSKNILFVI KPDV+KSPASDT
Sbjct: 1401 SEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDT 1460

Query: 1983 YIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTV------QEESEEEEVDE 2036
            Y+VFGEAKIEDLSQQ   AAAEKFKV  E  + + E+   P V      +EE EEEEVDE
Sbjct: 1461 YVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDE 1520

Query: 2037 TGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM 2078
             G+E++DIELVM+QANVSRAKAVRAL++N +DIVNAIMELTM
Sbjct: 1521 AGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM 1562



 Score = 99.0 bits (245), Expect = 4e-20
 Identities = 207/892 (23%), Positives = 311/892 (34%), Gaps = 154/892 (17%)

Query: 224  QSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQN---PGSLSLKGPVSPPAALSL-S 279
            Q G++ +      T   + +PQ ++T+++    SPQN    G L L     P AA ++  
Sbjct: 529  QEGISEILGQESVTAEKLPTPQ-EETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVP 587

Query: 280  TQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTI 339
             Q+   +T  Q +A   TPP           PL  +   S          A       TI
Sbjct: 588  RQAKEDLTLPQDSA--MTPP----------LPLQDTDLSS----------APKPVAAATI 625

Query: 340  SVDHSSTGASYPSQRSVIPPLPSRNEVV---PATVAAFPVVAPSVDKGPSTISSITCSPS 396
                +  G + P    + PPLP ++  +   P  VAA  +V+   ++G +       +P 
Sbjct: 626  VSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPP 685

Query: 397  GSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQ-------MPVSSVGTTPLVVTN---- 445
                        P     L S+P       LV+Q       +P  S  T PL + +    
Sbjct: 686  -----------LPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLS 734

Query: 446  --PCTIAAAPTTTFEVATCVSPPMSSG-----PISNIEPTS-PAALVMAPVAPKEPSTQV 497
              P  +AAA   + +    ++ P  S      P+ + + +S P  +  A +  ++    +
Sbjct: 735  SAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGL 794

Query: 498  ATTLRIPVSPPLP-DPEDLKNLPSSVLVKFPTQKDLQ---TVPASLEGAPFSPAQ-AGLT 552
                   ++PPLP    DL + P  V       +  +   T+P      P  P Q   L+
Sbjct: 795  TLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLS 854

Query: 553  TKKDPTVL--PLVQAAPKNSPSFQSTSSSPEIPLSP-EATLAKKSLGEPLPIGKPA---- 605
            +   P     P+ Q A +     Q ++ +P +PL   + + A K +    P+ + A    
Sbjct: 855  SAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGL 914

Query: 606  -----SSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAP 660
                 S+MT+PL +  +          GP S GP        P   A P      AG AP
Sbjct: 915  TLPQDSAMTAPLPLQDT----------GPTS-GP-------EPLAVATPQTLQAEAGCAP 956

Query: 661  TTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAP 720
                GT    T A    E   +L P+  P  E     LP VP  +    V        A 
Sbjct: 957  ----GTEPVATMAQQ--EVGEALGPR--PAPEEKNAALPTVPEPAALDQVQQDDPQPAAE 1008

Query: 721  LATLVLAPEIPKS---VPSPSLPPAGTPPGTKKVDGIS------------HTSALAPVAS 765
              T   A E   S   + + SLP   +  G +  + +S            HT   A   S
Sbjct: 1009 AGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDS 1068

Query: 766  SPKEC----PTEDSGASATASSKGTLTYLA------DSPSPLGVSVSPQTKRPPTK--KG 813
              KE       ++ G    A   G  + L       D+P      VS      P +  +G
Sbjct: 1069 PQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERG 1128

Query: 814  SAGPDTPIGNLSSPVSPVEASF--LPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT 871
             +G  TP   L S V+  EAS    PE+S+    S D       P  P+P  APT     
Sbjct: 1129 LSGKSTPEPTLPSAVA-TEASLDSCPESSVGAVSSLDRGC----PDAPAPTSAPTSQQPE 1183

Query: 872  PLSPKGVTLPPKETPTPSVVNLPFPKEG-----PATPAPKQAPALSMTSSSPKKARATPA 926
            P+   G    P E P+     L  P E      P+TP  +    L    S+P        
Sbjct: 1184 PVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRP---LGPDPSAPGTLAGAAL 1240

Query: 927  PKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAP 986
            P   P +P     P   +     P G    P P+      A   P+      T  P G  
Sbjct: 1241 PPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQ------AGVQPAAAAVSGTTQPLGTG 1294

Query: 987  TPPAATPPSPKGGPATPSPKGAPTPPAVTPP---SPKGSPAATPFPKGASTP 1035
               + +P SP   P   S         + PP    P   P +   P+G S P
Sbjct: 1295 PRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAP 1346



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 228/969 (23%), Positives = 330/969 (34%), Gaps = 140/969 (14%)

Query: 435  SVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPS 494
            ++G        P T+  AP    EVAT V+P        +      AA+ M P   +E  
Sbjct: 474  ALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAM-PQPSQEGI 532

Query: 495  TQVATTLRIPVSPPLPDPEDLKNL----PSSVLVKFPTQKDLQTVPASLEGAPFSPAQAG 550
            +++     +  +  LP P++  +L     S   +K     DL +    +  A   P QA 
Sbjct: 533  SEILGQESV-TAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQA- 590

Query: 551  LTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTS 610
                K+   LP   A     P   +  SS   P++  AT+  +   E L + +  S MT 
Sbjct: 591  ----KEDLTLPQDSAMTPPLPLQDTDLSSAPKPVA-AATIVSQQAEEGLTLPQD-SVMTP 644

Query: 611  PLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAA----FPLESADPAGVAPTTAKGT 666
            PL +  +         A         +  L  P  +A     PL+  D +      A   
Sbjct: 645  PLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA-- 702

Query: 667  STYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVL 726
                T  S   E  ++L     P        LPL  T   + P          P+A   L
Sbjct: 703  ---ATLVSQQAEEGLTL-----PQDSAMTPPLPLQDTDLSSAP---------KPVAAATL 745

Query: 727  APEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGT 786
              +  +   +     A TPP   +   +S  SA  PVA++       + G +    S  T
Sbjct: 746  VSQQAEEGLTLPQDSAMTPPLPLQDTDLS--SAPKPVAAATIVSQQAEEGLTLPQDSAMT 803

Query: 787  L------TYLADSPSPLGVS--VSPQTKRPPTKKGSAGPDTPI----GNLSSPVSPVEAS 834
                   T L+ +P P+  +  VS Q +   T    +    P+     +LSS   PV A+
Sbjct: 804  PPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAA 863

Query: 835  FLPENSLSFQG---SKDSPATTHSP-------TPPSPKGAPTPSAVTPLSPKGVTLPPKE 884
              P +  + +G    +DS  T   P       + P P  A TP  V+  + +G+TLP   
Sbjct: 864  -TPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATP--VSQQAEEGLTLPQDS 920

Query: 885  TPT-PSVVNLPFPKEGP-----ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKG 938
              T P  +    P  GP     ATP   QA A     + P    AT A + +  +  P+ 
Sbjct: 921  AMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPV---ATMAQQEVGEALGPRP 977

Query: 939  APTPP-AATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK 997
            AP    AA P  P+              PAA     +  P   +  G P        S  
Sbjct: 978  APEEKNAALPTVPE--------------PAALDQVQQDDPQPAAEAGTPWAAQEDADSTL 1023

Query: 998  GGPATPSPK-----GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052
            G  A   P+     G     A++ P  +    A      A T   A P SP+        
Sbjct: 1024 GMEALSLPEPASGAGEEIAEALSRPGREACLEAR-----AHTGDGAKPDSPQKETLEVEN 1078

Query: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAP-TPPAATPPSPKGGPATPSPKGAPMPPAATPP 1111
             +     P A    P+   A    +  P  PPAA P   +    +P+ +   +   +TP 
Sbjct: 1079 QQEGGLKPLAQEHGPRS--ALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPE 1136

Query: 1112 SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT------PPSPKGGL-A 1164
                   T P   A      + P    G  +   +G P  PA T       P P  GL +
Sbjct: 1137 ------PTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGS 1190

Query: 1165 TPPPKGAPT---TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1221
               P   P+   TP   PP     LA    KG P+TP   P  P      PS  G     
Sbjct: 1191 VEQPHEVPSVLGTPLLQPPE---NLA----KGQPSTPVDRPLGP-----DPSAPGTLAGA 1238

Query: 1222 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLAT- 1280
            A  P  P      P     P   +     P G    PPP+    P AA        L T 
Sbjct: 1239 ALPPLEP----PAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTG 1294

Query: 1281 -----PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP 1335
                  PH    +P V +  +        PP     PP + P SP G  G   P+     
Sbjct: 1295 PRVSLSPHSPLLSPKVASMDAKDLALQILPP--CQVPPPSGPQSPAGPQGLSAPEQQEDE 1352

Query: 1336 PAVTPPSPK 1344
             ++   SP+
Sbjct: 1353 DSLEEDSPR 1361



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 198/966 (20%), Positives = 328/966 (33%), Gaps = 134/966 (13%)

Query: 993  PPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052
            P + + GP T     A     +     +   A TP P   +     + P  +  P     
Sbjct: 13   PEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASW 72

Query: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112
              G    P+A     +GGP+   L             P+G  +      AP+ PA   P 
Sbjct: 73   DAGPGGAPSAWADPGEGGPSPMLL-------------PEGLSSQALSTEAPL-PATLEPR 118

Query: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPP------KGAPTTPAATPPSPKGGLATP 1166
               G  T     +P          +GG A+P P      +G  + P  +PP       TP
Sbjct: 119  IVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVP--SPPPDPDSFFTP 176

Query: 1167 PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP-SPKGGLATPSPKGAPTTPAATP 1225
            P     TT A  P     G A  S          +PP SP G   T       ++P+ + 
Sbjct: 177  PSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSL 236

Query: 1226 P--SPKGGLATPSPKGAPTTPAATPPSPKGGPATP---PPKGAPTPPAATPPSLKGGLAT 1280
               +P  GL  PS  G          SP+G         P G P PP++         ++
Sbjct: 237  SLLAPAEGLDFPSGWGL---------SPQGSMVDERELHPAGTPEPPSSESSLSADSSSS 287

Query: 1281 PPHKG--------APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA 1332
               +G        A +P +     P  G      +     P +     + +   P P G 
Sbjct: 288  WGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGG- 346

Query: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392
                        G     +T+ S     +  S  EG     A        +    S    
Sbjct: 347  ---------DLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYA 397

Query: 1393 PAIPSP--KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATS 1450
             A       G+P + A +        +   T E +   +KG          +++ AP TS
Sbjct: 398  EADDERLYSGEPHAQATL-----LQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTS 452

Query: 1451 APKGGPATPSSK------------GDPTLPAVTPPSPKEPPAPK-QVATSSSPKKA-PAT 1496
              +G   +   +            G  +   VTP + +  P  + +VAT  +P+     T
Sbjct: 453  -DRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEET 511

Query: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL---APKEALIPPAM 1553
             +  G  +    +P   +E  +    +    A       ++T  TL   +P+       +
Sbjct: 512  DSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGL 571

Query: 1554 TVPSPKKTPAIPT------------PKEAPATP-----SSKEASSPPAVTPSTYKGAPSP 1596
             +PS +K  A  T            P+++  TP      +  +S+P  V  +T     + 
Sbjct: 572  DLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAE 631

Query: 1597 KELLIP--PAVTSPSP------KEAPTPPA---VTPPSPEKGPATPAPKGTPTSPPVTPS 1645
            + L +P    +T P P        AP P A   +     E+G   P         P+  +
Sbjct: 632  EGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDT 691

Query: 1646 SLKDSPTSPASVT-----CKMGATVPQASKGLPAKKGPTALKEVLVAPAPE---STPIIT 1697
             L  +P   A+ T      + G T+PQ S   P    P  L++  ++ AP+   +  +++
Sbjct: 692  DLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTP----PLPLQDTDLSSAPKPVAAATLVS 747

Query: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757
                +G    + SA +PP+    +  + +  P   VA A ++  Q +   T   +D++ +
Sbjct: 748  QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP---VAAATIVSQQAEEGLTLP-QDSAMT 803

Query: 1758 PKGPL-------APPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTL 1810
            P  PL       AP    A+T ++  A E +    +SA     P     L  AP PV   
Sbjct: 804  PPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAA 863

Query: 1811 PPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPF-QSVLVNMPTPKSAG 1869
             P  Q       L  +S   P  P  + +L     P+P++   P  Q     +  P+ + 
Sbjct: 864  TPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSS--APKPVAAATPVSQQAEEGLTLPQDSA 921

Query: 1870 IPVPTP 1875
            +  P P
Sbjct: 922  MTAPLP 927



 Score = 79.0 bits (193), Expect = 5e-14
 Identities = 222/1032 (21%), Positives = 352/1032 (34%), Gaps = 210/1032 (20%)

Query: 4    EATETV-PATEQELPQPQAETA--VLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSA 60
            E+T TV P T Q  P  Q E A  V P +      +  GQ                   +
Sbjct: 478  ESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQ------------------ES 519

Query: 61   ANQASPFPSPSTIAS-------TPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISP 113
            A  A P PS   I+        T  ++P PQ  +   L     P++P  L    G  +  
Sbjct: 520  AAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTL----CPDSPQNLKEEGGLDL-- 573

Query: 114  AALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVI 173
                             PS   P+A   + P   ++    P +   +PP + + ++    
Sbjct: 574  -----------------PSGRKPVAAATIVPRQAKEDLTLPQDSAMTPP-LPLQDT---- 611

Query: 174  TLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQT 233
             LS+   P    T +++   E +  P+ +   P            P+    + ++S P+ 
Sbjct: 612  DLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTP------------PLPLQDTELSSAPKP 659

Query: 234  TPTTTLAIASPQVKDTTISSVLISPQNP-GSLSLKGPVSPPAALSL-STQSLPVVTSSQK 291
                TL     +   T      ++P  P     L     P AA +L S Q+   +T  Q 
Sbjct: 660  VAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQD 719

Query: 292  TAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYP 351
            +A   TPP           PL  +             SA       T+    +  G + P
Sbjct: 720  SA--MTPP----------LPLQDTDLS----------SAPKPVAAATLVSQQAEEGLTLP 757

Query: 352  SQRSVIPPLPSRN---EVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLS 408
               ++ PPLP ++      P  VAA  +V+   ++G              L +    +++
Sbjct: 758  QDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG--------------LTLPQDSAMT 803

Query: 409  PTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMS 468
            P                PL  Q    S    P+      +  A    T    + ++PP+ 
Sbjct: 804  P----------------PLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPL- 846

Query: 469  SGPISNIEPTSPAALVMAPVAPKEP-STQVATTLRIP----VSPPLP-DPEDLKNLPSSV 522
              P+ + + +S       PVA   P S Q    L +P    ++PPLP    DL + P  V
Sbjct: 847  --PLQDTDLSS----APKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV 900

Query: 523  LVKFPTQKDLQ---TVPA-SLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSS 578
                P  +  +   T+P  S   AP      G T+  +    PL  A P+   +    + 
Sbjct: 901  AAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPE----PLAVATPQTLQAEAGCAP 956

Query: 579  SPEIPLSPEATLAKKSLGE-----PLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAG 633
              E    P AT+A++ +GE     P P  K A+  T P    +   V + D     ++  
Sbjct: 957  GTE----PVATMAQQEVGEALGPRPAPEEKNAALPTVPEPA-ALDQVQQDDPQPAAEAGT 1011

Query: 634  PLLKSSLITPTVAAFPLESADPAGVA------PTTAKGTSTYTTTASPFLEGTVSLAPKN 687
            P         T+    L   +PA  A        +  G        +   +G    +P+ 
Sbjct: 1012 PWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQK 1071

Query: 688  HPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPS--PSLPPAGTP 745
              ++        L P A E+            P + L  A E+P + P+  P +  A   
Sbjct: 1072 ETLEVENQQEGGLKPLAQEH-----------GPRSALGGAREVPDAPPAACPEVSQARLL 1120

Query: 746  PGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYL----ADSPSPLGVSV 801
               ++  G+S  S   P  + P    TE S  S   SS G ++ L     D+P+P   + 
Sbjct: 1121 SPAREERGLSGKS--TPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAP---TS 1175

Query: 802  SPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSP 861
            +P +++P    G    + P    S   +P+     PEN    Q S          TP   
Sbjct: 1176 APTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQP--PENLAKGQPS----------TPVDR 1223

Query: 862  KGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKA 921
               P PSA  P +  G  LPP E P P +       + P   + +           P +A
Sbjct: 1224 PLGPDPSA--PGTLAGAALPPLEPPAPCLC------QDPQEDSVEDEEPPGSLGLPPPQA 1275

Query: 922  RATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP-----TPPAATPPSPKGG 976
               PA   +  +  P G     + +P SP   P   S           PP   PP P G 
Sbjct: 1276 GVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPP-PSGP 1334

Query: 977  PATPSPKGAPTP 988
             +   P+G   P
Sbjct: 1335 QSPAGPQGLSAP 1346



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 68/283 (24%), Positives = 93/283 (32%), Gaps = 42/283 (14%)

Query: 980  PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS------ 1033
            P P+   +  AA   +  GG         P P  +        P A P P+GAS      
Sbjct: 18   PGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASWDAGPG 77

Query: 1034 TPPAATPPSPKGSPAATPLPKGAPT--------TPAATLPSPKGGPATPSLKGAPTPPAA 1085
              P+A     +G P+   LP+G  +         PA   P    G  T     +P     
Sbjct: 78   GAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAART 137

Query: 1086 TPPSPKGGPATPSPKGAPMPP---------AATPPSPKGGLATPPHKGAPTTPAATPP-S 1135
                 +GG A+P P     PP           +PP       TPP     TT A  P   
Sbjct: 138  ALRDQEGGHASPDP-----PPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACG 192

Query: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP--SPKGGLATPSPKG 1193
            P G       +       + P SP G   T       ++P+ +    +P  GL  PS  G
Sbjct: 193  PHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWG 252

Query: 1194 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1236
                      SP+G +          TP   PPS +  L+  S
Sbjct: 253  L---------SPQGSMVDERELHPAGTP--EPPSSESSLSADS 284



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 61/240 (25%), Positives = 83/240 (34%), Gaps = 42/240 (17%)

Query: 902  TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT---PPAATPPSPKGGPATPS 958
            TP P     L++T   P K  A P P+G      P GAP+    P    PSP   P   S
Sbjct: 46   TPGPSH---LALTFL-PSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLS 101

Query: 959  PKWAPTP---PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT 1015
             +   T    PA   P    G  T     +P          +GG A+P P     PP + 
Sbjct: 102  SQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDP-----PPELC 156

Query: 1016 PPSPKGSPAATPFPKGASTPPAA-TPPSPKGSPAATP--------------LPKGAPTTP 1060
                   P+  P P    TPP+  T  +    PA  P              L    P +P
Sbjct: 157  SQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASP 216

Query: 1061 AATLPSPKGG--PATPSLKGAPTPPAATPPSPKGGPATPS----------PKGAPMPPAA 1108
            + +  +  G    ++PS   +   PA     P G   +P           P G P PP++
Sbjct: 217  SGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSS 276


>gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score =  319 bits (817), Expect = 2e-86
 Identities = 442/1571 (28%), Positives = 589/1571 (37%), Gaps = 247/1571 (15%)

Query: 625  SYAGPDSAGPLLKSSLITP---TVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTV 681
            ++A P   GP   S ++ P   +  A   E+  PA + P    G  T     SP    T 
Sbjct: 82   AWADPGEGGP---SPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTA 138

Query: 682  SLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPP 741
                +      G  +  P     S+     PSP        T    P  P       LP 
Sbjct: 139  LRDQEG-----GHASPDPPPELCSQGDLSVPSPPPDPDSFFT---PPSTPTKTTYALLPA 190

Query: 742  AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPS---PLG 798
             G     +  +       L    +SP        G S  +S   +L+ LA +     P G
Sbjct: 191  CGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSG 250

Query: 799  VSVSPQ-------------TKRPPTKKGSAGPDTPI-----GNLSSPVSPVEASFLPENS 840
              +SPQ             T  PP+ + S   D+       G+            +P   
Sbjct: 251  WGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAAL 310

Query: 841  LSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP 900
            L FQGS          TP SP+     +   P  P G      E  + S   L    +  
Sbjct: 311  LPFQGSLIFQVEAVEVTPLSPEEEEEEAVADP-DPGGDLAGEGEEDSTSASFLQSLSDLS 369

Query: 901  ATPAPKQAPAL----SMTSSSPKKARATPAPKGIPASPSPKGAPT---PPAATPPSPKGG 953
             T    +A A     S  SS    A    A      S  P    T             GG
Sbjct: 370  ITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGG 429

Query: 954  PATP------SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007
             A        +  WA    AA   S +G   +   +             +   AT +P  
Sbjct: 430  GAKGLQAQDGTVSWAVE--AAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHT 487

Query: 1008 APTPPAV-----TPPSPKGSPAATPFPKGASTPPAATP-PSPKGSPAATPLPKGAPTTPA 1061
                P +     T  +P+     T    G  +   A P PS +G         G  +  A
Sbjct: 488  LQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEIL----GQESVTA 543

Query: 1062 ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121
              LP+P+      SL   P  P       +GG   PS +         P   K  L  P 
Sbjct: 544  EKLPTPQ---EETSLTLCPDSPQNL--KEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQ 598

Query: 1122 HKGAPTTPAATPPSPKGGL---ATPPPKGAPTTPAATPPS----PKGGLATPPPKGAPTT 1174
                    A TPP P       + P P  A T  +         P+  + TPP     T 
Sbjct: 599  DS------AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTE 652

Query: 1175 PAATP-PSPKGGLATPSPKGAPTTP---AATPPSPKGGL---ATPSPKGAPTTPAATPPS 1227
             ++ P P     L +   +   T P   A TPP P       + P P  A T  +     
Sbjct: 653  LSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQ---Q 709

Query: 1228 PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP---PSLKGGLATPPHK 1284
             + GL  P         A TPP P           AP P AA        + GL  P   
Sbjct: 710  AEEGLTLPQDS------AMTPPLPLQDTDL---SSAPKPVAAATLVSQQAEEGLTLP--- 757

Query: 1285 GAPNPAVVTPPSPKGGPATSPPKGAPTP-PAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343
                 + +TPP P      S    AP P  AAT  S +   G   P+ +    A+TPP P
Sbjct: 758  ---QDSAMTPPLPLQDTDLS---SAPKPVAAATIVSQQAEEGLTLPQDS----AMTPPLP 807

Query: 1344 -KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402
             + T    A  P +     +  ++EG T P  +       AMTPP P +   + S     
Sbjct: 808  LQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS-------AMTPPLPLQDTDLSS----- 855

Query: 1403 TSPAVIPLSPKK-APATPVTR---EGAATPSKGDLTPPAVTPVSLKKAPATSAPKG-GPA 1457
                    +PK  A ATPV++   EG   P    +T     P+ L+    TS P+    A
Sbjct: 856  --------APKPVAAATPVSQQAEEGLTLPQDSAMT----APLPLQDTGPTSGPEPLAVA 903

Query: 1458 TPSSKGDPTLPAVTPPSPKEPP----APKQVATSSSPKKAPATPAPMGAPTLPAVIPSSP 1513
            TP      TL A    +P   P    A ++V  +  P+ AP            A +P+ P
Sbjct: 904  TPQ-----TLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKN--------AALPTVP 950

Query: 1514 KEVPATPSSRRDPI----APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK- 1568
            +        + DP     A T     +   +TL  +   +P   +    +   A+  P  
Sbjct: 951  EPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGR 1010

Query: 1569 ----EAPA-TPSSKEASSPPAVT---PSTYKGAPSPKELLIPPAVTSPSPKEAP-TPPAV 1619
                EA A T    +  SP   T    +  +G   P      P       +E P  PPA 
Sbjct: 1011 EACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAA 1070

Query: 1620 TPPSPEKGPATPAPK-----GTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPA 1674
             P   +    +PA +     G  T  P  PS++    +  +     +GA V    +G P 
Sbjct: 1071 CPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGA-VSSLDRGCPD 1129

Query: 1675 KKGPTA---------------LKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD 1719
               PT+               +++    P+   TP++  P     + + S+    P+ PD
Sbjct: 1130 APAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLA-KGQPSTPVDRPLGPD 1188

Query: 1720 PSAKNGSKG----PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLA-PPESKASTPLT 1774
            PSA     G    PL   AP      Q+DS +          P G L  PP      P  
Sbjct: 1189 PSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE-------DEEPPGSLGLPPPQAGVQPAA 1241

Query: 1775 AAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAP 1834
            AA      P      VS +P  P+  P     V ++  K   L   P   +  PS P +P
Sbjct: 1242 AAVSGTTQPLGTGPRVSLSPHSPLLSP----KVASMDAKDLALQILPPCQVPPPSGPQSP 1297

Query: 1835 ADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDS 1894
            A                           P   SA        + +  +    GSG  SDS
Sbjct: 1298 AG--------------------------PQGLSAPEQQEDEDSLEEDSPRALGSGQHSDS 1331

Query: 1895 D-ESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTG 1953
              ES  EL+EQD     T Q    A A   EE ++KAKQSRSEKKARKAMSKLGLRQ+ G
Sbjct: 1332 HGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQG 1391

Query: 1954 VTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAV 2013
            VTR+TI+KSKNILFVI KPDV+KSPASDTY+VFGEAKIEDLSQQ   AAAEKFKV  E  
Sbjct: 1392 VTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPS 1451

Query: 2014 SNIQENTQTPTV------QEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSN 2067
            + + E+   P V      +EE EEEEVDE G+E++DIELVM+QANVSRAKAVRAL++N +
Sbjct: 1452 ALVPESAPRPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHS 1511

Query: 2068 DIVNAIMELTM 2078
            DIVNAIMELTM
Sbjct: 1512 DIVNAIMELTM 1522



 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 205/872 (23%), Positives = 299/872 (34%), Gaps = 154/872 (17%)

Query: 224  QSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQN---PGSLSLKGPVSPPAALSL-S 279
            Q G++ +      T   + +PQ ++T+++    SPQN    G L L     P AA ++  
Sbjct: 529  QEGISEILGQESVTAEKLPTPQ-EETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVP 587

Query: 280  TQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTI 339
             Q+   +T  Q +A   TPP           PL  +   S          A       TI
Sbjct: 588  RQAKEDLTLPQDSA--MTPP----------LPLQDTDLSS----------APKPVAAATI 625

Query: 340  SVDHSSTGASYPSQRSVIPPLPSRNEVV---PATVAAFPVVAPSVDKGPSTISSITCSPS 396
                +  G + P    + PPLP ++  +   P  VAA  +V+   ++G +       +P 
Sbjct: 626  VSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPP 685

Query: 397  GSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQ-------MPVSSVGTTPLVVTN---- 445
                        P     L S+P       LV+Q       +P  S  T PL + +    
Sbjct: 686  -----------LPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLS 734

Query: 446  --PCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRI 503
              P  +AAA   + +    ++ P  S        T P  L    ++        AT +  
Sbjct: 735  SAPKPVAAATLVSQQAEEGLTLPQDSAM------TPPLPLQDTDLSSAPKPVAAATIVSQ 788

Query: 504  PVSPPLPDPEDLKNLPSSVLVKFPTQK-DLQTVPASLEGAPFSPAQA--GLTTKKDPTVL 560
                 L  P+D     S++    P Q  DL + P  +  A     QA  GLT  +D  + 
Sbjct: 789  QAEEGLTLPQD-----SAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMT 843

Query: 561  PLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASV 620
            P +     +     S++  P    +P +  A++ L  P       S+MT+PL +  +   
Sbjct: 844  PPLPLQDTDL----SSAPKPVAAATPVSQQAEEGLTLPQD-----SAMTAPLPLQDT--- 891

Query: 621  IKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGT 680
                   GP S GP        P   A P      AG AP    GT    T A    E  
Sbjct: 892  -------GPTS-GP-------EPLAVATPQTLQAEAGCAP----GTEPVATMAQQ--EVG 930

Query: 681  VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKS---VPSP 737
             +L P+  P  E     LP VP  +    V        A   T   A E   S   + + 
Sbjct: 931  EALGPR--PAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEAL 988

Query: 738  SLPPAGTPPGTKKVDGIS------------HTSALAPVASSPKEC----PTEDSGASATA 781
            SLP   +  G +  + +S            HT   A   S  KE       ++ G    A
Sbjct: 989  SLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLA 1048

Query: 782  SSKGTLTYLA------DSPSPLGVSVSPQTKRPPTK--KGSAGPDTPIGNLSSPVSPVEA 833
               G  + L       D+P      VS      P +  +G +G  TP   L S V+  EA
Sbjct: 1049 QEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVA-TEA 1107

Query: 834  SF--LPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVV 891
            S    PE+S+    S D       P  P+P  APT     P+   G    P E P+    
Sbjct: 1108 SLDSCPESSVGAVSSLDRGC----PDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGT 1163

Query: 892  NLPFPKEG-----PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT 946
             L  P E      P+TP  +    L    S+P        P   P +P     P   +  
Sbjct: 1164 PLLQPPENLAKGQPSTPVDRP---LGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1220

Query: 947  PPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK 1006
               P G    P P+      A   P+      T  P G     + +P SP   P   S  
Sbjct: 1221 DEEPPGSLGLPPPQ------AGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMD 1274

Query: 1007 GAPTPPAVTPP---SPKGSPAATPFPKGASTP 1035
                   + PP    P   P +   P+G S P
Sbjct: 1275 AKDLALQILPPCQVPPPSGPQSPAGPQGLSAP 1306



 Score = 88.6 bits (218), Expect = 6e-17
 Identities = 217/950 (22%), Positives = 318/950 (33%), Gaps = 142/950 (14%)

Query: 435  SVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPS 494
            ++G        P T+  AP    EVAT V+P        +      AA+ M P   +E  
Sbjct: 474  ALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAM-PQPSQEGI 532

Query: 495  TQVATTLRIPVSPPLPDPEDLKNL----PSSVLVKFPTQKDLQTVPASLEGAPFSPAQAG 550
            +++     +  +  LP P++  +L     S   +K     DL +    +  A   P QA 
Sbjct: 533  SEILGQESV-TAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQA- 590

Query: 551  LTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTS 610
                K+   LP   A     P   +  SS   P++  AT+  +   E L + +  S MT 
Sbjct: 591  ----KEDLTLPQDSAMTPPLPLQDTDLSSAPKPVA-AATIVSQQAEEGLTLPQD-SVMTP 644

Query: 611  PLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAA----FPLESADPAGVAPTTAKGT 666
            PL +  +         A         +  L  P  +A     PL+  D +      A   
Sbjct: 645  PLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA-- 702

Query: 667  STYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVL 726
                T  S   E  ++L     P        LPL  T   + P          P+A   L
Sbjct: 703  ---ATLVSQQAEEGLTL-----PQDSAMTPPLPLQDTDLSSAP---------KPVAAATL 745

Query: 727  APEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGT 786
              +  +   +     A TPP   +   +S  SA  PVA++       + G +    S  T
Sbjct: 746  VSQQAEEGLTLPQDSAMTPPLPLQDTDLS--SAPKPVAAATIVSQQAEEGLTLPQDSAMT 803

Query: 787  L------TYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS 840
                   T L+ +P P+  +         +++   G   P  +  +P  P++        
Sbjct: 804  PPLPLQDTDLSSAPKPVAAATI------VSQQAEEGLTLPQDSAMTPPLPLQ-------- 849

Query: 841  LSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPT-PSVVNLPFPKEG 899
                        T   + P P  A TP  V+  + +G+TLP     T P  +    P  G
Sbjct: 850  -----------DTDLSSAPKPVAAATP--VSQQAEEGLTLPQDSAMTAPLPLQDTGPTSG 896

Query: 900  P-----ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP-AATPPSPKGG 953
            P     ATP   QA A     + P    AT A + +  +  P+ AP    AA P  P+  
Sbjct: 897  PEPLAVATPQTLQAEAGCAPGTEPV---ATMAQQEVGEALGPRPAPEEKNAALPTVPE-- 951

Query: 954  PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK-----GA 1008
                        PAA     +  P   +  G P        S  G  A   P+     G 
Sbjct: 952  ------------PAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGE 999

Query: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPK 1068
                A++ P  +    A      A T   A P SP+         +     P A    P+
Sbjct: 1000 EIAEALSRPGREACLEAR-----AHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPR 1054

Query: 1069 GGPATPSLKGAP-TPPAATPPSPKGGPATPSPKGAPMPPAATP-PSPKGGLATPPH-KGA 1125
               A    +  P  PPAA P   +    +P+ +   +   +TP P+    +AT       
Sbjct: 1055 S--ALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSC 1112

Query: 1126 PTTPAATPPSPKGGLATPP-PKGAPTTPAATPPSPKGGL-ATPPPKGAPT---TPAATPP 1180
            P +      S   G    P P  APT   +  P P  GL +   P   P+   TP   PP
Sbjct: 1113 PESSVGAVSSLDRGCPDAPAPTSAPT---SQQPEPVLGLGSVEQPHEVPSVLGTPLLQPP 1169

Query: 1181 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA 1240
                 LA    KG P+TP   P  P      PS  G     A  P  P      P     
Sbjct: 1170 E---NLA----KGQPSTPVDRPLGP-----DPSAPGTLAGAALPPLEP----PAPCLCQD 1213

Query: 1241 PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLAT------PPHKGAPNPAVVTP 1294
            P   +     P G    PPP+    P AA        L T       PH    +P V + 
Sbjct: 1214 PQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASM 1273

Query: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPK 1344
             +        PP     PP + P SP G  G   P+      ++   SP+
Sbjct: 1274 DAKDLALQILPP--CQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPR 1321



 Score = 85.9 bits (211), Expect = 4e-16
 Identities = 209/1020 (20%), Positives = 346/1020 (33%), Gaps = 145/1020 (14%)

Query: 993  PPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052
            P + + GP T     A     +     +   A TP P   +     + P  +  P     
Sbjct: 13   PEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASW 72

Query: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112
              G    P+A     +GGP+   L             P+G  +      AP+ PA   P 
Sbjct: 73   DAGPGGAPSAWADPGEGGPSPMLL-------------PEGLSSQALSTEAPL-PATLEPR 118

Query: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPP------KGAPTTPAATPPSPKGGLATP 1166
               G  T     +P          +GG A+P P      +G  + P  +PP       TP
Sbjct: 119  IVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVP--SPPPDPDSFFTP 176

Query: 1167 PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP-SPKGGLATPSPKGAPTTPAATP 1225
            P     TT A  P     G A  S          +PP SP G   T       ++P+ + 
Sbjct: 177  PSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSL 236

Query: 1226 P--SPKGGLATPSPKGAPTTPAATPPSPKGGPATP---PPKGAPTPPAATPPSLKGGLAT 1280
               +P  GL  PS  G          SP+G         P G P PP++         ++
Sbjct: 237  SLLAPAEGLDFPSGWGL---------SPQGSMVDERELHPAGTPEPPSSESSLSADSSSS 287

Query: 1281 PPHKG--------APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA 1332
               +G        A +P +     P  G      +     P +     + +   P P G 
Sbjct: 288  WGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGG- 346

Query: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392
                        G     +T+ S     +  S  EG     A        +    S    
Sbjct: 347  ---------DLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYA 397

Query: 1393 PAIPSP--KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATS 1450
             A       G+P + A +        +   T E +   +KG          +++ AP TS
Sbjct: 398  EADDERLYSGEPHAQATL-----LQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTS 452

Query: 1451 APKGGPATPSSK------------GDPTLPAVTPPSPKEPPAPK-QVATSSSPKKA-PAT 1496
              +G   +   +            G  +   VTP + +  P  + +VAT  +P+     T
Sbjct: 453  -DRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEET 511

Query: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL---APKEALIPPAM 1553
             +  G  +    +P   +E  +    +    A       ++T  TL   +P+       +
Sbjct: 512  DSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGL 571

Query: 1554 TVPSPKKTPAIPT------------PKEAPATP-----SSKEASSPPAVTPSTYKGAPSP 1596
             +PS +K  A  T            P+++  TP      +  +S+P  V  +T     + 
Sbjct: 572  DLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAE 631

Query: 1597 KELLIP--PAVTSPSP------KEAPTPPA---VTPPSPEKGPATPAPKGTPTSPPVTPS 1645
            + L +P    +T P P        AP P A   +     E+G   P         P+  +
Sbjct: 632  EGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDT 691

Query: 1646 SLKDSPTSPASVT-----CKMGATVPQASKGLPAKKGPTALKEVLVAPAPE---STPIIT 1697
             L  +P   A+ T      + G T+PQ S   P    P  L++  ++ AP+   +  +++
Sbjct: 692  DLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTP----PLPLQDTDLSSAPKPVAAATLVS 747

Query: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757
                +G    + SA +PP+    +  + +  P   VA A ++  Q +   T   +D++ +
Sbjct: 748  QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP---VAAATIVSQQAEEGLTLP-QDSAMT 803

Query: 1758 PKGPL-------APPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTL 1810
            P  PL       AP    A+T ++  A E +    +SA     P     L  AP PV   
Sbjct: 804  PPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAA 863

Query: 1811 PPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGI 1870
             P  Q   +  GL L   S   AP    +  P   PEP++           + TP++   
Sbjct: 864  TPVSQ--QAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLA-----------VATPQTLQA 910

Query: 1871 PVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKA 1930
                    +PV    +    E+      PE E+  +     + A L    + D +P ++A
Sbjct: 911  EAGCAPGTEPVATMAQQEVGEALGPRPAPE-EKNAALPTVPEPAALDQVQQDDPQPAAEA 969



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 224/1033 (21%), Positives = 329/1033 (31%), Gaps = 252/1033 (24%)

Query: 4    EATETV-PATEQELPQPQAETA--VLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSA 60
            E+T TV P T Q  P  Q E A  V P +      +  GQ                   +
Sbjct: 478  ESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQ------------------ES 519

Query: 61   ANQASPFPSPSTIAS-------TPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISP 113
            A  A P PS   I+        T  ++P PQ  +   L     P++P  L    G  +  
Sbjct: 520  AAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTL----CPDSPQNLKEEGGLDL-- 573

Query: 114  AALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPP---SVAVAESG 170
                             PS   P+A   + P   ++    P +   +PP         S 
Sbjct: 574  -----------------PSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSA 616

Query: 171  SVITLSAPIAPSEPKTNLNKVPSEVVPNP---------KGTPSPPCIVSTVPYHCVTPMA 221
                 +A I   + +  L  +P + V  P            P P    + V       + 
Sbjct: 617  PKPVAAATIVSQQAEEGLT-LPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLT 675

Query: 222  SIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSL--KGPVSPPAAL--- 276
              Q    + P     T L+ A   V   T    L+S Q    L+L     ++PP  L   
Sbjct: 676  LPQDSAMTPPLPLQDTDLSSAPKPVAAAT----LVSQQAEEGLTLPQDSAMTPPLPLQDT 731

Query: 277  SLSTQSLPV----VTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALS 332
             LS+   PV    + S Q   G   P D   S  +   PL  +             SA  
Sbjct: 732  DLSSAPKPVAAATLVSQQAEEGLTLPQD---SAMTPPLPLQDTDLS----------SAPK 778

Query: 333  DPTVKTISVDHSSTGASYPSQRSVIPPLPSRN---EVVPATVAAFPVVAPSVDKGPSTIS 389
                 TI    +  G + P   ++ PPLP ++      P  VAA  +V+   ++G +   
Sbjct: 779  PVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQ 838

Query: 390  SITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTI 449
                +P             P     L S+P      P+ A  PVS      L +     +
Sbjct: 839  DSAMTPP-----------LPLQDTDLSSAPK-----PVAAATPVSQQAEEGLTLPQDSAM 882

Query: 450  AAAPTTTFEVATCVSPPMSSGPISNIEPTSPAA-LVMAPVAPKEPSTQ-VATTLRIPVSP 507
                       T   P   +GP S  EP + A    +   A   P T+ VAT  +  V  
Sbjct: 883  -----------TAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGE 931

Query: 508  ---PLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQ 564
               P P PE+ KN                               A L T  +P  L  VQ
Sbjct: 932  ALGPRPAPEE-KN-------------------------------AALPTVPEPAALDQVQ 959

Query: 565  AAPKNSPSFQSTSSSP-EIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKT 623
               ++ P   + + +P       ++TL  ++L  P P       +   L      + ++ 
Sbjct: 960  ---QDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEA 1016

Query: 624  DSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSL 683
             ++ G D A P       +P      +E+    G+ P                      L
Sbjct: 1017 RAHTG-DGAKP------DSPQKETLEVENQQEGGLKP----------------------L 1047

Query: 684  APKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPE--IPKSVPSPSLPP 741
            A ++ P     L     VP A    P A  P+ + A L +          KS P P+LP 
Sbjct: 1048 AQEHGP--RSALGGAREVPDA----PPAACPEVSQARLLSPAREERGLSGKSTPEPTLPS 1101

Query: 742  AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSP-LGVS 800
            A     T+        S++  V+S  + CP   +  SA  S +         P P LG+ 
Sbjct: 1102 A---VATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQ---------PEPVLGLG 1149

Query: 801  VSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS 860
               Q    P+  G     TP+      + P      PEN    Q S          TP  
Sbjct: 1150 SVEQPHEVPSVLG-----TPL------LQP------PENLAKGQPS----------TPVD 1182

Query: 861  PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK 920
                P PSA  P +  G  LPP E P P +       + P   + +           P +
Sbjct: 1183 RPLGPDPSA--PGTLAGAALPPLEPPAPCLC------QDPQEDSVEDEEPPGSLGLPPPQ 1234

Query: 921  ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP-----TPPAATPPSPKG 975
            A   PA   +  +  P G     + +P SP   P   S           PP   PP P G
Sbjct: 1235 AGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPP-PSG 1293

Query: 976  GPATPSPKGAPTP 988
              +   P+G   P
Sbjct: 1294 PQSPAGPQGLSAP 1306



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 68/283 (24%), Positives = 93/283 (32%), Gaps = 42/283 (14%)

Query: 980  PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS------ 1033
            P P+   +  AA   +  GG         P P  +        P A P P+GAS      
Sbjct: 18   PGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASWDAGPG 77

Query: 1034 TPPAATPPSPKGSPAATPLPKGAPT--------TPAATLPSPKGGPATPSLKGAPTPPAA 1085
              P+A     +G P+   LP+G  +         PA   P    G  T     +P     
Sbjct: 78   GAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAART 137

Query: 1086 TPPSPKGGPATPSPKGAPMPP---------AATPPSPKGGLATPPHKGAPTTPAATPP-S 1135
                 +GG A+P P     PP           +PP       TPP     TT A  P   
Sbjct: 138  ALRDQEGGHASPDP-----PPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACG 192

Query: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP--SPKGGLATPSPKG 1193
            P G       +       + P SP G   T       ++P+ +    +P  GL  PS  G
Sbjct: 193  PHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWG 252

Query: 1194 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1236
                      SP+G +          TP   PPS +  L+  S
Sbjct: 253  L---------SPQGSMVDERELHPAGTP--EPPSSESSLSADS 284



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 61/240 (25%), Positives = 83/240 (34%), Gaps = 42/240 (17%)

Query: 902  TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT---PPAATPPSPKGGPATPS 958
            TP P     L++T   P K  A P P+G      P GAP+    P    PSP   P   S
Sbjct: 46   TPGPSH---LALTFL-PSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLS 101

Query: 959  PKWAPTP---PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT 1015
             +   T    PA   P    G  T     +P          +GG A+P P     PP + 
Sbjct: 102  SQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDP-----PPELC 156

Query: 1016 PPSPKGSPAATPFPKGASTPPAA-TPPSPKGSPAATP--------------LPKGAPTTP 1060
                   P+  P P    TPP+  T  +    PA  P              L    P +P
Sbjct: 157  SQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASP 216

Query: 1061 AATLPSPKGG--PATPSLKGAPTPPAATPPSPKGGPATPS----------PKGAPMPPAA 1108
            + +  +  G    ++PS   +   PA     P G   +P           P G P PP++
Sbjct: 217  SGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSS 276


>gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score =  319 bits (817), Expect = 2e-86
 Identities = 442/1571 (28%), Positives = 589/1571 (37%), Gaps = 247/1571 (15%)

Query: 625  SYAGPDSAGPLLKSSLITP---TVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTV 681
            ++A P   GP   S ++ P   +  A   E+  PA + P    G  T     SP    T 
Sbjct: 82   AWADPGEGGP---SPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTA 138

Query: 682  SLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPP 741
                +      G  +  P     S+     PSP        T    P  P       LP 
Sbjct: 139  LRDQEG-----GHASPDPPPELCSQGDLSVPSPPPDPDSFFT---PPSTPTKTTYALLPA 190

Query: 742  AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPS---PLG 798
             G     +  +       L    +SP        G S  +S   +L+ LA +     P G
Sbjct: 191  CGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSG 250

Query: 799  VSVSPQ-------------TKRPPTKKGSAGPDTPI-----GNLSSPVSPVEASFLPENS 840
              +SPQ             T  PP+ + S   D+       G+            +P   
Sbjct: 251  WGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAAL 310

Query: 841  LSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP 900
            L FQGS          TP SP+     +   P  P G      E  + S   L    +  
Sbjct: 311  LPFQGSLIFQVEAVEVTPLSPEEEEEEAVADP-DPGGDLAGEGEEDSTSASFLQSLSDLS 369

Query: 901  ATPAPKQAPAL----SMTSSSPKKARATPAPKGIPASPSPKGAPT---PPAATPPSPKGG 953
             T    +A A     S  SS    A    A      S  P    T             GG
Sbjct: 370  ITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGG 429

Query: 954  PATP------SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007
             A        +  WA    AA   S +G   +   +             +   AT +P  
Sbjct: 430  GAKGLQAQDGTVSWAVE--AAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHT 487

Query: 1008 APTPPAV-----TPPSPKGSPAATPFPKGASTPPAATP-PSPKGSPAATPLPKGAPTTPA 1061
                P +     T  +P+     T    G  +   A P PS +G         G  +  A
Sbjct: 488  LQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEIL----GQESVTA 543

Query: 1062 ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121
              LP+P+      SL   P  P       +GG   PS +         P   K  L  P 
Sbjct: 544  EKLPTPQ---EETSLTLCPDSPQNL--KEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQ 598

Query: 1122 HKGAPTTPAATPPSPKGGL---ATPPPKGAPTTPAATPPS----PKGGLATPPPKGAPTT 1174
                    A TPP P       + P P  A T  +         P+  + TPP     T 
Sbjct: 599  DS------AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTE 652

Query: 1175 PAATP-PSPKGGLATPSPKGAPTTP---AATPPSPKGGL---ATPSPKGAPTTPAATPPS 1227
             ++ P P     L +   +   T P   A TPP P       + P P  A T  +     
Sbjct: 653  LSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQ---Q 709

Query: 1228 PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP---PSLKGGLATPPHK 1284
             + GL  P         A TPP P           AP P AA        + GL  P   
Sbjct: 710  AEEGLTLPQDS------AMTPPLPLQDTDL---SSAPKPVAAATLVSQQAEEGLTLP--- 757

Query: 1285 GAPNPAVVTPPSPKGGPATSPPKGAPTP-PAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343
                 + +TPP P      S    AP P  AAT  S +   G   P+ +    A+TPP P
Sbjct: 758  ---QDSAMTPPLPLQDTDLS---SAPKPVAAATIVSQQAEEGLTLPQDS----AMTPPLP 807

Query: 1344 -KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402
             + T    A  P +     +  ++EG T P  +       AMTPP P +   + S     
Sbjct: 808  LQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDS-------AMTPPLPLQDTDLSS----- 855

Query: 1403 TSPAVIPLSPKK-APATPVTR---EGAATPSKGDLTPPAVTPVSLKKAPATSAPKG-GPA 1457
                    +PK  A ATPV++   EG   P    +T     P+ L+    TS P+    A
Sbjct: 856  --------APKPVAAATPVSQQAEEGLTLPQDSAMT----APLPLQDTGPTSGPEPLAVA 903

Query: 1458 TPSSKGDPTLPAVTPPSPKEPP----APKQVATSSSPKKAPATPAPMGAPTLPAVIPSSP 1513
            TP      TL A    +P   P    A ++V  +  P+ AP            A +P+ P
Sbjct: 904  TPQ-----TLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKN--------AALPTVP 950

Query: 1514 KEVPATPSSRRDPI----APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK- 1568
            +        + DP     A T     +   +TL  +   +P   +    +   A+  P  
Sbjct: 951  EPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGR 1010

Query: 1569 ----EAPA-TPSSKEASSPPAVT---PSTYKGAPSPKELLIPPAVTSPSPKEAP-TPPAV 1619
                EA A T    +  SP   T    +  +G   P      P       +E P  PPA 
Sbjct: 1011 EACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAA 1070

Query: 1620 TPPSPEKGPATPAPK-----GTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPA 1674
             P   +    +PA +     G  T  P  PS++    +  +     +GA V    +G P 
Sbjct: 1071 CPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGA-VSSLDRGCPD 1129

Query: 1675 KKGPTA---------------LKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD 1719
               PT+               +++    P+   TP++  P     + + S+    P+ PD
Sbjct: 1130 APAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLA-KGQPSTPVDRPLGPD 1188

Query: 1720 PSAKNGSKG----PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLA-PPESKASTPLT 1774
            PSA     G    PL   AP      Q+DS +          P G L  PP      P  
Sbjct: 1189 PSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE-------DEEPPGSLGLPPPQAGVQPAA 1241

Query: 1775 AAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAP 1834
            AA      P      VS +P  P+  P     V ++  K   L   P   +  PS P +P
Sbjct: 1242 AAVSGTTQPLGTGPRVSLSPHSPLLSP----KVASMDAKDLALQILPPCQVPPPSGPQSP 1297

Query: 1835 ADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDS 1894
            A                           P   SA        + +  +    GSG  SDS
Sbjct: 1298 AG--------------------------PQGLSAPEQQEDEDSLEEDSPRALGSGQHSDS 1331

Query: 1895 D-ESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTG 1953
              ES  EL+EQD     T Q    A A   EE ++KAKQSRSEKKARKAMSKLGLRQ+ G
Sbjct: 1332 HGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQG 1391

Query: 1954 VTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAV 2013
            VTR+TI+KSKNILFVI KPDV+KSPASDTY+VFGEAKIEDLSQQ   AAAEKFKV  E  
Sbjct: 1392 VTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPS 1451

Query: 2014 SNIQENTQTPTV------QEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSN 2067
            + + E+   P V      +EE EEEEVDE G+E++DIELVM+QANVSRAKAVRAL++N +
Sbjct: 1452 ALVPESAPRPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHS 1511

Query: 2068 DIVNAIMELTM 2078
            DIVNAIMELTM
Sbjct: 1512 DIVNAIMELTM 1522



 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 205/872 (23%), Positives = 299/872 (34%), Gaps = 154/872 (17%)

Query: 224  QSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQN---PGSLSLKGPVSPPAALSL-S 279
            Q G++ +      T   + +PQ ++T+++    SPQN    G L L     P AA ++  
Sbjct: 529  QEGISEILGQESVTAEKLPTPQ-EETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVP 587

Query: 280  TQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTI 339
             Q+   +T  Q +A   TPP           PL  +   S          A       TI
Sbjct: 588  RQAKEDLTLPQDSA--MTPP----------LPLQDTDLSS----------APKPVAAATI 625

Query: 340  SVDHSSTGASYPSQRSVIPPLPSRNEVV---PATVAAFPVVAPSVDKGPSTISSITCSPS 396
                +  G + P    + PPLP ++  +   P  VAA  +V+   ++G +       +P 
Sbjct: 626  VSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPP 685

Query: 397  GSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQ-------MPVSSVGTTPLVVTN---- 445
                        P     L S+P       LV+Q       +P  S  T PL + +    
Sbjct: 686  -----------LPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLS 734

Query: 446  --PCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRI 503
              P  +AAA   + +    ++ P  S        T P  L    ++        AT +  
Sbjct: 735  SAPKPVAAATLVSQQAEEGLTLPQDSAM------TPPLPLQDTDLSSAPKPVAAATIVSQ 788

Query: 504  PVSPPLPDPEDLKNLPSSVLVKFPTQK-DLQTVPASLEGAPFSPAQA--GLTTKKDPTVL 560
                 L  P+D     S++    P Q  DL + P  +  A     QA  GLT  +D  + 
Sbjct: 789  QAEEGLTLPQD-----SAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMT 843

Query: 561  PLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASV 620
            P +     +     S++  P    +P +  A++ L  P       S+MT+PL +  +   
Sbjct: 844  PPLPLQDTDL----SSAPKPVAAATPVSQQAEEGLTLPQD-----SAMTAPLPLQDT--- 891

Query: 621  IKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGT 680
                   GP S GP        P   A P      AG AP    GT    T A    E  
Sbjct: 892  -------GPTS-GP-------EPLAVATPQTLQAEAGCAP----GTEPVATMAQQ--EVG 930

Query: 681  VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKS---VPSP 737
             +L P+  P  E     LP VP  +    V        A   T   A E   S   + + 
Sbjct: 931  EALGPR--PAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEAL 988

Query: 738  SLPPAGTPPGTKKVDGIS------------HTSALAPVASSPKEC----PTEDSGASATA 781
            SLP   +  G +  + +S            HT   A   S  KE       ++ G    A
Sbjct: 989  SLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLA 1048

Query: 782  SSKGTLTYLA------DSPSPLGVSVSPQTKRPPTK--KGSAGPDTPIGNLSSPVSPVEA 833
               G  + L       D+P      VS      P +  +G +G  TP   L S V+  EA
Sbjct: 1049 QEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVA-TEA 1107

Query: 834  SF--LPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVV 891
            S    PE+S+    S D       P  P+P  APT     P+   G    P E P+    
Sbjct: 1108 SLDSCPESSVGAVSSLDRGC----PDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGT 1163

Query: 892  NLPFPKEG-----PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT 946
             L  P E      P+TP  +    L    S+P        P   P +P     P   +  
Sbjct: 1164 PLLQPPENLAKGQPSTPVDRP---LGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1220

Query: 947  PPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK 1006
               P G    P P+      A   P+      T  P G     + +P SP   P   S  
Sbjct: 1221 DEEPPGSLGLPPPQ------AGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMD 1274

Query: 1007 GAPTPPAVTPP---SPKGSPAATPFPKGASTP 1035
                   + PP    P   P +   P+G S P
Sbjct: 1275 AKDLALQILPPCQVPPPSGPQSPAGPQGLSAP 1306



 Score = 88.6 bits (218), Expect = 6e-17
 Identities = 217/950 (22%), Positives = 318/950 (33%), Gaps = 142/950 (14%)

Query: 435  SVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPS 494
            ++G        P T+  AP    EVAT V+P        +      AA+ M P   +E  
Sbjct: 474  ALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAM-PQPSQEGI 532

Query: 495  TQVATTLRIPVSPPLPDPEDLKNL----PSSVLVKFPTQKDLQTVPASLEGAPFSPAQAG 550
            +++     +  +  LP P++  +L     S   +K     DL +    +  A   P QA 
Sbjct: 533  SEILGQESV-TAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQA- 590

Query: 551  LTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTS 610
                K+   LP   A     P   +  SS   P++  AT+  +   E L + +  S MT 
Sbjct: 591  ----KEDLTLPQDSAMTPPLPLQDTDLSSAPKPVA-AATIVSQQAEEGLTLPQD-SVMTP 644

Query: 611  PLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAA----FPLESADPAGVAPTTAKGT 666
            PL +  +         A         +  L  P  +A     PL+  D +      A   
Sbjct: 645  PLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA-- 702

Query: 667  STYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVL 726
                T  S   E  ++L     P        LPL  T   + P          P+A   L
Sbjct: 703  ---ATLVSQQAEEGLTL-----PQDSAMTPPLPLQDTDLSSAP---------KPVAAATL 745

Query: 727  APEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGT 786
              +  +   +     A TPP   +   +S  SA  PVA++       + G +    S  T
Sbjct: 746  VSQQAEEGLTLPQDSAMTPPLPLQDTDLS--SAPKPVAAATIVSQQAEEGLTLPQDSAMT 803

Query: 787  L------TYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS 840
                   T L+ +P P+  +         +++   G   P  +  +P  P++        
Sbjct: 804  PPLPLQDTDLSSAPKPVAAATI------VSQQAEEGLTLPQDSAMTPPLPLQ-------- 849

Query: 841  LSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPT-PSVVNLPFPKEG 899
                        T   + P P  A TP  V+  + +G+TLP     T P  +    P  G
Sbjct: 850  -----------DTDLSSAPKPVAAATP--VSQQAEEGLTLPQDSAMTAPLPLQDTGPTSG 896

Query: 900  P-----ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP-AATPPSPKGG 953
            P     ATP   QA A     + P    AT A + +  +  P+ AP    AA P  P+  
Sbjct: 897  PEPLAVATPQTLQAEAGCAPGTEPV---ATMAQQEVGEALGPRPAPEEKNAALPTVPE-- 951

Query: 954  PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK-----GA 1008
                        PAA     +  P   +  G P        S  G  A   P+     G 
Sbjct: 952  ------------PAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGE 999

Query: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPK 1068
                A++ P  +    A      A T   A P SP+         +     P A    P+
Sbjct: 1000 EIAEALSRPGREACLEAR-----AHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPR 1054

Query: 1069 GGPATPSLKGAP-TPPAATPPSPKGGPATPSPKGAPMPPAATP-PSPKGGLATPPH-KGA 1125
               A    +  P  PPAA P   +    +P+ +   +   +TP P+    +AT       
Sbjct: 1055 S--ALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSC 1112

Query: 1126 PTTPAATPPSPKGGLATPP-PKGAPTTPAATPPSPKGGL-ATPPPKGAPT---TPAATPP 1180
            P +      S   G    P P  APT   +  P P  GL +   P   P+   TP   PP
Sbjct: 1113 PESSVGAVSSLDRGCPDAPAPTSAPT---SQQPEPVLGLGSVEQPHEVPSVLGTPLLQPP 1169

Query: 1181 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA 1240
                 LA    KG P+TP   P  P      PS  G     A  P  P      P     
Sbjct: 1170 E---NLA----KGQPSTPVDRPLGP-----DPSAPGTLAGAALPPLEP----PAPCLCQD 1213

Query: 1241 PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLAT------PPHKGAPNPAVVTP 1294
            P   +     P G    PPP+    P AA        L T       PH    +P V + 
Sbjct: 1214 PQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASM 1273

Query: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPK 1344
             +        PP     PP + P SP G  G   P+      ++   SP+
Sbjct: 1274 DAKDLALQILPP--CQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPR 1321



 Score = 85.9 bits (211), Expect = 4e-16
 Identities = 209/1020 (20%), Positives = 346/1020 (33%), Gaps = 145/1020 (14%)

Query: 993  PPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052
            P + + GP T     A     +     +   A TP P   +     + P  +  P     
Sbjct: 13   PEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASW 72

Query: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112
              G    P+A     +GGP+   L             P+G  +      AP+ PA   P 
Sbjct: 73   DAGPGGAPSAWADPGEGGPSPMLL-------------PEGLSSQALSTEAPL-PATLEPR 118

Query: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPP------KGAPTTPAATPPSPKGGLATP 1166
               G  T     +P          +GG A+P P      +G  + P  +PP       TP
Sbjct: 119  IVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVP--SPPPDPDSFFTP 176

Query: 1167 PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP-SPKGGLATPSPKGAPTTPAATP 1225
            P     TT A  P     G A  S          +PP SP G   T       ++P+ + 
Sbjct: 177  PSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSL 236

Query: 1226 P--SPKGGLATPSPKGAPTTPAATPPSPKGGPATP---PPKGAPTPPAATPPSLKGGLAT 1280
               +P  GL  PS  G          SP+G         P G P PP++         ++
Sbjct: 237  SLLAPAEGLDFPSGWGL---------SPQGSMVDERELHPAGTPEPPSSESSLSADSSSS 287

Query: 1281 PPHKG--------APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA 1332
               +G        A +P +     P  G      +     P +     + +   P P G 
Sbjct: 288  WGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGG- 346

Query: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392
                        G     +T+ S     +  S  EG     A        +    S    
Sbjct: 347  ---------DLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYA 397

Query: 1393 PAIPSP--KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATS 1450
             A       G+P + A +        +   T E +   +KG          +++ AP TS
Sbjct: 398  EADDERLYSGEPHAQATL-----LQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTS 452

Query: 1451 APKGGPATPSSK------------GDPTLPAVTPPSPKEPPAPK-QVATSSSPKKA-PAT 1496
              +G   +   +            G  +   VTP + +  P  + +VAT  +P+     T
Sbjct: 453  -DRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEET 511

Query: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL---APKEALIPPAM 1553
             +  G  +    +P   +E  +    +    A       ++T  TL   +P+       +
Sbjct: 512  DSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGL 571

Query: 1554 TVPSPKKTPAIPT------------PKEAPATP-----SSKEASSPPAVTPSTYKGAPSP 1596
             +PS +K  A  T            P+++  TP      +  +S+P  V  +T     + 
Sbjct: 572  DLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAE 631

Query: 1597 KELLIP--PAVTSPSP------KEAPTPPA---VTPPSPEKGPATPAPKGTPTSPPVTPS 1645
            + L +P    +T P P        AP P A   +     E+G   P         P+  +
Sbjct: 632  EGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDT 691

Query: 1646 SLKDSPTSPASVT-----CKMGATVPQASKGLPAKKGPTALKEVLVAPAPE---STPIIT 1697
             L  +P   A+ T      + G T+PQ S   P    P  L++  ++ AP+   +  +++
Sbjct: 692  DLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTP----PLPLQDTDLSSAPKPVAAATLVS 747

Query: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757
                +G    + SA +PP+    +  + +  P   VA A ++  Q +   T   +D++ +
Sbjct: 748  QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP---VAAATIVSQQAEEGLTLP-QDSAMT 803

Query: 1758 PKGPL-------APPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTL 1810
            P  PL       AP    A+T ++  A E +    +SA     P     L  AP PV   
Sbjct: 804  PPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAA 863

Query: 1811 PPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGI 1870
             P  Q   +  GL L   S   AP    +  P   PEP++           + TP++   
Sbjct: 864  TPVSQ--QAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLA-----------VATPQTLQA 910

Query: 1871 PVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKA 1930
                    +PV    +    E+      PE E+  +     + A L    + D +P ++A
Sbjct: 911  EAGCAPGTEPVATMAQQEVGEALGPRPAPE-EKNAALPTVPEPAALDQVQQDDPQPAAEA 969



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 224/1033 (21%), Positives = 329/1033 (31%), Gaps = 252/1033 (24%)

Query: 4    EATETV-PATEQELPQPQAETA--VLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSA 60
            E+T TV P T Q  P  Q E A  V P +      +  GQ                   +
Sbjct: 478  ESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQ------------------ES 519

Query: 61   ANQASPFPSPSTIAS-------TPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISP 113
            A  A P PS   I+        T  ++P PQ  +   L     P++P  L    G  +  
Sbjct: 520  AAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTL----CPDSPQNLKEEGGLDL-- 573

Query: 114  AALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPP---SVAVAESG 170
                             PS   P+A   + P   ++    P +   +PP         S 
Sbjct: 574  -----------------PSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSA 616

Query: 171  SVITLSAPIAPSEPKTNLNKVPSEVVPNP---------KGTPSPPCIVSTVPYHCVTPMA 221
                 +A I   + +  L  +P + V  P            P P    + V       + 
Sbjct: 617  PKPVAAATIVSQQAEEGLT-LPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLT 675

Query: 222  SIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSL--KGPVSPPAAL--- 276
              Q    + P     T L+ A   V   T    L+S Q    L+L     ++PP  L   
Sbjct: 676  LPQDSAMTPPLPLQDTDLSSAPKPVAAAT----LVSQQAEEGLTLPQDSAMTPPLPLQDT 731

Query: 277  SLSTQSLPV----VTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALS 332
             LS+   PV    + S Q   G   P D   S  +   PL  +             SA  
Sbjct: 732  DLSSAPKPVAAATLVSQQAEEGLTLPQD---SAMTPPLPLQDTDLS----------SAPK 778

Query: 333  DPTVKTISVDHSSTGASYPSQRSVIPPLPSRN---EVVPATVAAFPVVAPSVDKGPSTIS 389
                 TI    +  G + P   ++ PPLP ++      P  VAA  +V+   ++G +   
Sbjct: 779  PVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQ 838

Query: 390  SITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTI 449
                +P             P     L S+P      P+ A  PVS      L +     +
Sbjct: 839  DSAMTPP-----------LPLQDTDLSSAPK-----PVAAATPVSQQAEEGLTLPQDSAM 882

Query: 450  AAAPTTTFEVATCVSPPMSSGPISNIEPTSPAA-LVMAPVAPKEPSTQ-VATTLRIPVSP 507
                       T   P   +GP S  EP + A    +   A   P T+ VAT  +  V  
Sbjct: 883  -----------TAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGE 931

Query: 508  ---PLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQ 564
               P P PE+ KN                               A L T  +P  L  VQ
Sbjct: 932  ALGPRPAPEE-KN-------------------------------AALPTVPEPAALDQVQ 959

Query: 565  AAPKNSPSFQSTSSSP-EIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKT 623
               ++ P   + + +P       ++TL  ++L  P P       +   L      + ++ 
Sbjct: 960  ---QDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEA 1016

Query: 624  DSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSL 683
             ++ G D A P       +P      +E+    G+ P                      L
Sbjct: 1017 RAHTG-DGAKP------DSPQKETLEVENQQEGGLKP----------------------L 1047

Query: 684  APKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPE--IPKSVPSPSLPP 741
            A ++ P     L     VP A    P A  P+ + A L +          KS P P+LP 
Sbjct: 1048 AQEHGP--RSALGGAREVPDA----PPAACPEVSQARLLSPAREERGLSGKSTPEPTLPS 1101

Query: 742  AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSP-LGVS 800
            A     T+        S++  V+S  + CP   +  SA  S +         P P LG+ 
Sbjct: 1102 A---VATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQ---------PEPVLGLG 1149

Query: 801  VSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS 860
               Q    P+  G     TP+      + P      PEN    Q S          TP  
Sbjct: 1150 SVEQPHEVPSVLG-----TPL------LQP------PENLAKGQPS----------TPVD 1182

Query: 861  PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK 920
                P PSA  P +  G  LPP E P P +       + P   + +           P +
Sbjct: 1183 RPLGPDPSA--PGTLAGAALPPLEPPAPCLC------QDPQEDSVEDEEPPGSLGLPPPQ 1234

Query: 921  ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP-----TPPAATPPSPKG 975
            A   PA   +  +  P G     + +P SP   P   S           PP   PP P G
Sbjct: 1235 AGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPP-PSG 1293

Query: 976  GPATPSPKGAPTP 988
              +   P+G   P
Sbjct: 1294 PQSPAGPQGLSAP 1306



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 68/283 (24%), Positives = 93/283 (32%), Gaps = 42/283 (14%)

Query: 980  PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS------ 1033
            P P+   +  AA   +  GG         P P  +        P A P P+GAS      
Sbjct: 18   PGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASWDAGPG 77

Query: 1034 TPPAATPPSPKGSPAATPLPKGAPT--------TPAATLPSPKGGPATPSLKGAPTPPAA 1085
              P+A     +G P+   LP+G  +         PA   P    G  T     +P     
Sbjct: 78   GAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAART 137

Query: 1086 TPPSPKGGPATPSPKGAPMPP---------AATPPSPKGGLATPPHKGAPTTPAATPP-S 1135
                 +GG A+P P     PP           +PP       TPP     TT A  P   
Sbjct: 138  ALRDQEGGHASPDP-----PPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACG 192

Query: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP--SPKGGLATPSPKG 1193
            P G       +       + P SP G   T       ++P+ +    +P  GL  PS  G
Sbjct: 193  PHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWG 252

Query: 1194 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1236
                      SP+G +          TP   PPS +  L+  S
Sbjct: 253  L---------SPQGSMVDERELHPAGTP--EPPSSESSLSADS 284



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 61/240 (25%), Positives = 83/240 (34%), Gaps = 42/240 (17%)

Query: 902  TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT---PPAATPPSPKGGPATPS 958
            TP P     L++T   P K  A P P+G      P GAP+    P    PSP   P   S
Sbjct: 46   TPGPSH---LALTFL-PSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLS 101

Query: 959  PKWAPTP---PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT 1015
             +   T    PA   P    G  T     +P          +GG A+P P     PP + 
Sbjct: 102  SQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDP-----PPELC 156

Query: 1016 PPSPKGSPAATPFPKGASTPPAA-TPPSPKGSPAATP--------------LPKGAPTTP 1060
                   P+  P P    TPP+  T  +    PA  P              L    P +P
Sbjct: 157  SQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASP 216

Query: 1061 AATLPSPKGG--PATPSLKGAPTPPAATPPSPKGGPATPS----------PKGAPMPPAA 1108
            + +  +  G    ++PS   +   PA     P G   +P           P G P PP++
Sbjct: 217  SGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSS 276


>gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score =  317 bits (813), Expect = 6e-86
 Identities = 441/1571 (28%), Positives = 589/1571 (37%), Gaps = 247/1571 (15%)

Query: 625  SYAGPDSAGPLLKSSLITP---TVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTV 681
            ++A P   GP   S ++ P   +  A   E+  PA + P    G  T     SP    T 
Sbjct: 82   AWADPGEGGP---SPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTA 138

Query: 682  SLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPP 741
                +      G  +  P     S+     PSP        T    P  P       LP 
Sbjct: 139  LRDQEG-----GHASPDPPPELCSQGDLSVPSPPPDPDSFFT---PPSTPTKTTYALLPA 190

Query: 742  AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPS---PLG 798
             G     +  +       L    +SP        G S  +S   +L+ LA +     P G
Sbjct: 191  CGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSG 250

Query: 799  VSVSPQ-------------TKRPPTKKGSAGPDTPI-----GNLSSPVSPVEASFLPENS 840
              +SPQ             T  PP+ + S   D+       G+            +P   
Sbjct: 251  WGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAAL 310

Query: 841  LSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP 900
            L FQGS          TP SP+     +   P  P G      E  + S   L    +  
Sbjct: 311  LPFQGSLIFQVEAVEVTPLSPEEEEEEAVADP-DPGGDLAGEGEEDSTSASFLQSLSDLS 369

Query: 901  ATPAPKQAPAL----SMTSSSPKKARATPAPKGIPASPSPKGAPT---PPAATPPSPKGG 953
             T    +A A     S  SS    A    A      S  P    T             GG
Sbjct: 370  ITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGG 429

Query: 954  PATP------SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007
             A        +  WA    AA   S +G   +   +             +   AT +P  
Sbjct: 430  GAKGLQAQDGTVSWAVE--AAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHT 487

Query: 1008 APTPPAV-----TPPSPKGSPAATPFPKGASTPPAATP-PSPKGSPAATPLPKGAPTTPA 1061
                P +     T  +P+     T    G  +   A P PS +G         G  +  A
Sbjct: 488  LQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEIL----GQESVTA 543

Query: 1062 ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121
              LP+P+      SL   P  P       +GG   PS +         P   +  L  P 
Sbjct: 544  EKLPTPQ---EETSLTLCPDSPQNL--KEEGGLDLPSGRKPVAAATIVPRQAEEDLTLPQ 598

Query: 1122 HKGAPTTPAATPPSPKGGL---ATPPPKGAPTTPAATPPS----PKGGLATPPPKGAPTT 1174
                    A TPP P       + P P  A T  +         P+  + TPP     T 
Sbjct: 599  DS------AMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTE 652

Query: 1175 PAATP-PSPKGGLATPSPKGAPTTP---AATPPSPKGGL---ATPSPKGAPTTPAATPPS 1227
             ++ P P     L +   +   T P   A TPP P       + P P  A T  +     
Sbjct: 653  LSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQ---Q 709

Query: 1228 PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP---PSLKGGLATPPHK 1284
             + GL  P         A TPP P           AP P AA        + GL  P   
Sbjct: 710  AEEGLTLPQDS------AMTPPLPLQDTDL---SSAPKPVAAATLVSQQAEEGLTLP--- 757

Query: 1285 GAPNPAVVTPPSPKGGPATSPPKGAPTP-PAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343
                 + +TPP P      S    AP P  AAT  S +   G   P+ +    A+TPP P
Sbjct: 758  ---QDSAMTPPLPLQDTDLS---SAPKPVAAATIVSQQAEEGLTLPQDS----AMTPPLP 807

Query: 1344 -KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402
             + T    A  P +     +  ++EG T P  +       AMTPP P +   + S     
Sbjct: 808  LQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS-------AMTPPLPLQDTDLSS----- 855

Query: 1403 TSPAVIPLSPKK-APATPVTR---EGAATPSKGDLTPPAVTPVSLKKAPATSAPKG-GPA 1457
                    +PK  A ATPV++   EG   P    +T     P+ L+    TS P+    A
Sbjct: 856  --------APKPVAAATPVSQQAEEGLTLPQDSAMT----APLPLQDTGPTSGPEPLAVA 903

Query: 1458 TPSSKGDPTLPAVTPPSPKEPP----APKQVATSSSPKKAPATPAPMGAPTLPAVIPSSP 1513
            TP      TL A    +P   P    A ++V  +  P+ AP            A +P+ P
Sbjct: 904  TPQ-----TLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKN--------AALPTVP 950

Query: 1514 KEVPATPSSRRDPI----APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK- 1568
            +        + DP     A T     +   +TL  +   +P   +    +   A+  P  
Sbjct: 951  EPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGR 1010

Query: 1569 ----EAPA-TPSSKEASSPPAVT---PSTYKGAPSPKELLIPPAVTSPSPKEAP-TPPAV 1619
                EA A T    +  SP   T    +  +G   P      P       +E P  PPA 
Sbjct: 1011 EACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAA 1070

Query: 1620 TPPSPEKGPATPAPK-----GTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPA 1674
             P   +    +PA +     G  T  P  PS++    +  +     +GA V    +G P 
Sbjct: 1071 CPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGA-VSSLDRGCPD 1129

Query: 1675 KKGPTA---------------LKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD 1719
               PT+               +++    P+   TP++  P     + + S+    P+ PD
Sbjct: 1130 APAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLA-KGQPSTPVDRPLGPD 1188

Query: 1720 PSAKNGSKG----PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLA-PPESKASTPLT 1774
            PSA     G    PL   AP      Q+DS +          P G L  PP      P  
Sbjct: 1189 PSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE-------DEEPPGSLGLPPPQAGVQPAA 1241

Query: 1775 AAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAP 1834
            AA      P      VS +P  P+  P     V ++  K   L   P   +  PS P +P
Sbjct: 1242 AAVSGTTQPLGTGPRVSLSPHSPLLSP----KVASMDAKDLALQILPPCQVPPPSGPQSP 1297

Query: 1835 ADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDS 1894
            A                           P   SA        + +  +    GSG  SDS
Sbjct: 1298 AG--------------------------PQGLSAPEQQEDEDSLEEDSPRALGSGQHSDS 1331

Query: 1895 D-ESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTG 1953
              ES  EL+EQD     T Q    A A   EE ++KAKQSRSEKKARKAMSKLGLRQ+ G
Sbjct: 1332 HGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQG 1391

Query: 1954 VTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAV 2013
            VTR+TI+KSKNILFVI KPDV+KSPASDTY+VFGEAKIEDLSQQ   AAAEKFKV  E  
Sbjct: 1392 VTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPS 1451

Query: 2014 SNIQENTQTPTV------QEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSN 2067
            + + E+   P V      +EE EEEEVDE G+E++DIELVM+QANVSRAKAVRAL++N +
Sbjct: 1452 ALVPESAPRPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHS 1511

Query: 2068 DIVNAIMELTM 2078
            DIVNAIMELTM
Sbjct: 1512 DIVNAIMELTM 1522



 Score = 92.0 bits (227), Expect = 5e-18
 Identities = 205/872 (23%), Positives = 299/872 (34%), Gaps = 154/872 (17%)

Query: 224  QSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQN---PGSLSLKGPVSPPAALSL-S 279
            Q G++ +      T   + +PQ ++T+++    SPQN    G L L     P AA ++  
Sbjct: 529  QEGISEILGQESVTAEKLPTPQ-EETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVP 587

Query: 280  TQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTI 339
             Q+   +T  Q +A   TPP           PL  +   S          A       TI
Sbjct: 588  RQAEEDLTLPQDSA--MTPP----------LPLQDTDLSS----------APKPVAAATI 625

Query: 340  SVDHSSTGASYPSQRSVIPPLPSRNEVV---PATVAAFPVVAPSVDKGPSTISSITCSPS 396
                +  G + P    + PPLP ++  +   P  VAA  +V+   ++G +       +P 
Sbjct: 626  VSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPP 685

Query: 397  GSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQ-------MPVSSVGTTPLVVTN---- 445
                        P     L S+P       LV+Q       +P  S  T PL + +    
Sbjct: 686  -----------LPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLS 734

Query: 446  --PCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRI 503
              P  +AAA   + +    ++ P  S        T P  L    ++        AT +  
Sbjct: 735  SAPKPVAAATLVSQQAEEGLTLPQDSAM------TPPLPLQDTDLSSAPKPVAAATIVSQ 788

Query: 504  PVSPPLPDPEDLKNLPSSVLVKFPTQK-DLQTVPASLEGAPFSPAQA--GLTTKKDPTVL 560
                 L  P+D     S++    P Q  DL + P  +  A     QA  GLT  +D  + 
Sbjct: 789  QAEEGLTLPQD-----SAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMT 843

Query: 561  PLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASV 620
            P +     +     S++  P    +P +  A++ L  P       S+MT+PL +  +   
Sbjct: 844  PPLPLQDTDL----SSAPKPVAAATPVSQQAEEGLTLPQD-----SAMTAPLPLQDT--- 891

Query: 621  IKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGT 680
                   GP S GP        P   A P      AG AP    GT    T A    E  
Sbjct: 892  -------GPTS-GP-------EPLAVATPQTLQAEAGCAP----GTEPVATMAQQ--EVG 930

Query: 681  VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKS---VPSP 737
             +L P+  P  E     LP VP  +    V        A   T   A E   S   + + 
Sbjct: 931  EALGPR--PAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEAL 988

Query: 738  SLPPAGTPPGTKKVDGIS------------HTSALAPVASSPKEC----PTEDSGASATA 781
            SLP   +  G +  + +S            HT   A   S  KE       ++ G    A
Sbjct: 989  SLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLA 1048

Query: 782  SSKGTLTYLA------DSPSPLGVSVSPQTKRPPTK--KGSAGPDTPIGNLSSPVSPVEA 833
               G  + L       D+P      VS      P +  +G +G  TP   L S V+  EA
Sbjct: 1049 QEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVA-TEA 1107

Query: 834  SF--LPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVV 891
            S    PE+S+    S D       P  P+P  APT     P+   G    P E P+    
Sbjct: 1108 SLDSCPESSVGAVSSLDRGC----PDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGT 1163

Query: 892  NLPFPKEG-----PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT 946
             L  P E      P+TP  +    L    S+P        P   P +P     P   +  
Sbjct: 1164 PLLQPPENLAKGQPSTPVDRP---LGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVE 1220

Query: 947  PPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK 1006
               P G    P P+      A   P+      T  P G     + +P SP   P   S  
Sbjct: 1221 DEEPPGSLGLPPPQ------AGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMD 1274

Query: 1007 GAPTPPAVTPP---SPKGSPAATPFPKGASTP 1035
                   + PP    P   P +   P+G S P
Sbjct: 1275 AKDLALQILPPCQVPPPSGPQSPAGPQGLSAP 1306



 Score = 85.9 bits (211), Expect = 4e-16
 Identities = 209/1020 (20%), Positives = 346/1020 (33%), Gaps = 145/1020 (14%)

Query: 993  PPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052
            P + + GP T     A     +     +   A TP P   +     + P  +  P     
Sbjct: 13   PEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASW 72

Query: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112
              G    P+A     +GGP+   L             P+G  +      AP+ PA   P 
Sbjct: 73   DAGPGGAPSAWADPGEGGPSPMLL-------------PEGLSSQALSTEAPL-PATLEPR 118

Query: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPP------KGAPTTPAATPPSPKGGLATP 1166
               G  T     +P          +GG A+P P      +G  + P  +PP       TP
Sbjct: 119  IVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVP--SPPPDPDSFFTP 176

Query: 1167 PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP-SPKGGLATPSPKGAPTTPAATP 1225
            P     TT A  P     G A  S          +PP SP G   T       ++P+ + 
Sbjct: 177  PSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSL 236

Query: 1226 P--SPKGGLATPSPKGAPTTPAATPPSPKGGPATP---PPKGAPTPPAATPPSLKGGLAT 1280
               +P  GL  PS  G          SP+G         P G P PP++         ++
Sbjct: 237  SLLAPAEGLDFPSGWGL---------SPQGSMVDERELHPAGTPEPPSSESSLSADSSSS 287

Query: 1281 PPHKG--------APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA 1332
               +G        A +P +     P  G      +     P +     + +   P P G 
Sbjct: 288  WGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGG- 346

Query: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392
                        G     +T+ S     +  S  EG     A        +    S    
Sbjct: 347  ---------DLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYA 397

Query: 1393 PAIPSP--KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATS 1450
             A       G+P + A +        +   T E +   +KG          +++ AP TS
Sbjct: 398  EADDERLYSGEPHAQATL-----LQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTS 452

Query: 1451 APKGGPATPSSK------------GDPTLPAVTPPSPKEPPAPK-QVATSSSPKKA-PAT 1496
              +G   +   +            G  +   VTP + +  P  + +VAT  +P+     T
Sbjct: 453  -DRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEET 511

Query: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL---APKEALIPPAM 1553
             +  G  +    +P   +E  +    +    A       ++T  TL   +P+       +
Sbjct: 512  DSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGL 571

Query: 1554 TVPSPKKTPAIPT------------PKEAPATP-----SSKEASSPPAVTPSTYKGAPSP 1596
             +PS +K  A  T            P+++  TP      +  +S+P  V  +T     + 
Sbjct: 572  DLPSGRKPVAAATIVPRQAEEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAE 631

Query: 1597 KELLIP--PAVTSPSP------KEAPTPPA---VTPPSPEKGPATPAPKGTPTSPPVTPS 1645
            + L +P    +T P P        AP P A   +     E+G   P         P+  +
Sbjct: 632  EGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDT 691

Query: 1646 SLKDSPTSPASVT-----CKMGATVPQASKGLPAKKGPTALKEVLVAPAPE---STPIIT 1697
             L  +P   A+ T      + G T+PQ S   P    P  L++  ++ AP+   +  +++
Sbjct: 692  DLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTP----PLPLQDTDLSSAPKPVAAATLVS 747

Query: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757
                +G    + SA +PP+    +  + +  P   VA A ++  Q +   T   +D++ +
Sbjct: 748  QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP---VAAATIVSQQAEEGLTLP-QDSAMT 803

Query: 1758 PKGPL-------APPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTL 1810
            P  PL       AP    A+T ++  A E +    +SA     P     L  AP PV   
Sbjct: 804  PPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAA 863

Query: 1811 PPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGI 1870
             P  Q   +  GL L   S   AP    +  P   PEP++           + TP++   
Sbjct: 864  TPVSQ--QAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLA-----------VATPQTLQA 910

Query: 1871 PVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKA 1930
                    +PV    +    E+      PE E+  +     + A L    + D +P ++A
Sbjct: 911  EAGCAPGTEPVATMAQQEVGEALGPRPAPE-EKNAALPTVPEPAALDQVQQDDPQPAAEA 969



 Score = 79.0 bits (193), Expect = 5e-14
 Identities = 205/892 (22%), Positives = 292/892 (32%), Gaps = 119/892 (13%)

Query: 435  SVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPS 494
            ++G        P T+  AP    EVAT V+P        +      AA+ M P   +E  
Sbjct: 474  ALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAM-PQPSQEGI 532

Query: 495  TQVATTLRIPVSPPLPDPEDLKNL----PSSVLVKFPTQKDLQTVPASLEGAPFSPAQAG 550
            +++     +  +  LP P++  +L     S   +K     DL +    +  A   P QA 
Sbjct: 533  SEILGQESV-TAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQA- 590

Query: 551  LTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTS 610
                ++   LP   A     P   +  SS   P++  AT+  +   E L + +  S MT 
Sbjct: 591  ----EEDLTLPQDSAMTPPLPLQDTDLSSAPKPVA-AATIVSQQAEEGLTLPQD-SVMTP 644

Query: 611  PLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAA----FPLESADPAGVAPTTAKGT 666
            PL +  +         A         +  L  P  +A     PL+  D +      A   
Sbjct: 645  PLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA-- 702

Query: 667  STYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVL 726
                T  S   E  ++L     P        LPL  T   + P          P+A   L
Sbjct: 703  ---ATLVSQQAEEGLTL-----PQDSAMTPPLPLQDTDLSSAP---------KPVAAATL 745

Query: 727  APEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGT 786
              +  +   +     A TPP   +   +S  SA  PVA++       + G +    S  T
Sbjct: 746  VSQQAEEGLTLPQDSAMTPPLPLQDTDLS--SAPKPVAAATIVSQQAEEGLTLPQDSAMT 803

Query: 787  L------TYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS 840
                   T L+ +P P+  +         +++   G   P  +  +P  P     L +  
Sbjct: 804  PPLPLQDTDLSSAPKPVAAATL------VSQQAEEGLTLPQDSAMTPPLP-----LQDTD 852

Query: 841  LSFQGSKDSPATTHSPTPPSPKGAPTPSAVT---PLSPKGVTLPPKETPTPSVVNLPFPK 897
            LS      + AT  S         P  SA+T   PL   G    P   P P  V  P   
Sbjct: 853  LSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTG----PTSGPEPLAVATPQTL 908

Query: 898  EGPATPAPKQAPALSMTSSSPKKARA-TPAPK----GIPASPSPKGAPTPPAATPPSPKG 952
            +  A  AP   P  +M      +A    PAP+     +P  P P  A        P P  
Sbjct: 909  QAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEP-AALDQVQQDDPQPAA 967

Query: 953  GPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP 1012
               TP   WA    A +    +   + P P        A   S  G  A    + A T  
Sbjct: 968  EAGTP---WAAQEDADSTLGME-ALSLPEPASGAGEEIAEALSRPGREACLEAR-AHTGD 1022

Query: 1013 AVTPPSPKGSPAATPFPKGASTPPAAT---PPSPKGSPAATP--LPKGAPTTPAATLPSP 1067
               P SP+         +     P A    P S  G     P   P   P    A L SP
Sbjct: 1023 GAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSP 1082

Query: 1068 K------GGPATPSLKGAPTPPAATP--------PSPKGGPATPSPKGAPMPPAAT---- 1109
                    G +TP     PT P+A          P    G  +   +G P  PA T    
Sbjct: 1083 AREERGLSGKSTPE----PTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPT 1138

Query: 1110 --PPSPKGGLAT--PPHK--GAPTTPAATPPS--PKGGLATPPPKGAPTTPAATPPSPKG 1161
               P P  GL +   PH+      TP   PP    KG  +TP  +  P  P  + P    
Sbjct: 1139 SQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDR--PLGPDPSAPGTLA 1196

Query: 1162 GLATPPPKGAPTTPAATPPSPKGGLATPSPKGA---PTTPAATPPSPKGGLATPSPKGAP 1218
            G A PP +  P  P       +  +    P G+   P   A   P+      T  P G  
Sbjct: 1197 GAALPPLE--PPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTG 1254

Query: 1219 TTPAATPPSPKGGLATPSPKGAPTTPAATPP---SPKGGPATPP-PKGAPTP 1266
               + +P SP       S           PP    P  GP +P  P+G   P
Sbjct: 1255 PRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAP 1306



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 218/1027 (21%), Positives = 340/1027 (33%), Gaps = 240/1027 (23%)

Query: 4    EATETV-PATEQELPQPQAETA--VLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSA 60
            E+T TV P T Q  P  Q E A  V P +      +  GQ                   +
Sbjct: 478  ESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQ------------------ES 519

Query: 61   ANQASPFPSPSTIAS-------TPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISP 113
            A  A P PS   I+        T  ++P PQ  +   L     P++P  L    G  +  
Sbjct: 520  AAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTL----CPDSPQNLKEEGGLDL-- 573

Query: 114  AALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVI 173
                             PS   P+A   + P   ++    P +   +PP + + ++    
Sbjct: 574  -----------------PSGRKPVAAATIVPRQAEEDLTLPQDSAMTPP-LPLQDT---- 611

Query: 174  TLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQT 233
             LS+   P    T +++   E +  P+ +   P            P+    + ++S P+ 
Sbjct: 612  DLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTP------------PLPLQDTELSSAPKP 659

Query: 234  TPTTTLAIASPQVKDTTISSVLISPQNP-GSLSLKGPVSPPAALSL-STQSLPVVTSSQK 291
                TL     +   T      ++P  P     L     P AA +L S Q+   +T  Q 
Sbjct: 660  VAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQD 719

Query: 292  TAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYP 351
            +A   TPP           PL  +             SA       T+    +  G + P
Sbjct: 720  SA--MTPP----------LPLQDTDLS----------SAPKPVAAATLVSQQAEEGLTLP 757

Query: 352  SQRSVIPPLPSRN---EVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLS 408
               ++ PPLP ++      P  VAA  +V+   ++G +       +P             
Sbjct: 758  QDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPP-----------L 806

Query: 409  PTTSLILKSSPNATYHYPLVAQ-------MPVSSVGTTPLVVTN------PCTIAAAPTT 455
            P     L S+P       LV+Q       +P  S  T PL + +      P  +AAA   
Sbjct: 807  PLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPV 866

Query: 456  TFEVATCVSPPMSSG-----PISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLP 510
            + +    ++ P  S      P+ +  PTS       P+A   P T  A     P + P+ 
Sbjct: 867  SQQAEEGLTLPQDSAMTAPLPLQDTGPTSGP----EPLAVATPQTLQAEAGCAPGTEPV- 921

Query: 511  DPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNS 570
                      + + +    + L   PA  E        A L T  +P  L  VQ   ++ 
Sbjct: 922  ----------ATMAQQEVGEALGPRPAPEE------KNAALPTVPEPAALDQVQ---QDD 962

Query: 571  PSFQSTSSSP-EIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGP 629
            P   + + +P       ++TL  ++L  P P       +   L      + ++  ++ G 
Sbjct: 963  PQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTG- 1021

Query: 630  DSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHP 689
            D A P       +P      +E+    G+ P                      LA ++ P
Sbjct: 1022 DGAKP------DSPQKETLEVENQQEGGLKP----------------------LAQEHGP 1053

Query: 690  VKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPE--IPKSVPSPSLPPAGTPPG 747
                 L     VP A    P A  P+ + A L +          KS P P+LP A     
Sbjct: 1054 --RSALGGAREVPDA----PPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSA---VA 1104

Query: 748  TKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSP-LGVSVSPQTK 806
            T+        S++  V+S  + CP   +  SA  S +         P P LG+    Q  
Sbjct: 1105 TEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQ---------PEPVLGLGSVEQPH 1155

Query: 807  RPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPT 866
              P+  G     TP+      + P      PEN    Q S          TP      P 
Sbjct: 1156 EVPSVLG-----TPL------LQP------PENLAKGQPS----------TPVDRPLGPD 1188

Query: 867  PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPA 926
            PSA  P +  G  LPP E P P +       + P   + +           P +A   PA
Sbjct: 1189 PSA--PGTLAGAALPPLEPPAPCLC------QDPQEDSVEDEEPPGSLGLPPPQAGVQPA 1240

Query: 927  PKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP-----TPPAATPPSPKGGPATPS 981
               +  +  P G     + +P SP   P   S           PP   PP P G  +   
Sbjct: 1241 AAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPP-PSGPQSPAG 1299

Query: 982  PKGAPTP 988
            P+G   P
Sbjct: 1300 PQGLSAP 1306



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 68/283 (24%), Positives = 93/283 (32%), Gaps = 42/283 (14%)

Query: 980  PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS------ 1033
            P P+   +  AA   +  GG         P P  +        P A P P+GAS      
Sbjct: 18   PGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASWDAGPG 77

Query: 1034 TPPAATPPSPKGSPAATPLPKGAPT--------TPAATLPSPKGGPATPSLKGAPTPPAA 1085
              P+A     +G P+   LP+G  +         PA   P    G  T     +P     
Sbjct: 78   GAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAART 137

Query: 1086 TPPSPKGGPATPSPKGAPMPP---------AATPPSPKGGLATPPHKGAPTTPAATPP-S 1135
                 +GG A+P P     PP           +PP       TPP     TT A  P   
Sbjct: 138  ALRDQEGGHASPDP-----PPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACG 192

Query: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP--SPKGGLATPSPKG 1193
            P G       +       + P SP G   T       ++P+ +    +P  GL  PS  G
Sbjct: 193  PHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWG 252

Query: 1194 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1236
                      SP+G +          TP   PPS +  L+  S
Sbjct: 253  L---------SPQGSMVDERELHPAGTP--EPPSSESSLSADS 284



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 61/240 (25%), Positives = 83/240 (34%), Gaps = 42/240 (17%)

Query: 902  TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT---PPAATPPSPKGGPATPS 958
            TP P     L++T   P K  A P P+G      P GAP+    P    PSP   P   S
Sbjct: 46   TPGPSH---LALTFL-PSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLS 101

Query: 959  PKWAPTP---PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT 1015
             +   T    PA   P    G  T     +P          +GG A+P P     PP + 
Sbjct: 102  SQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDP-----PPELC 156

Query: 1016 PPSPKGSPAATPFPKGASTPPAA-TPPSPKGSPAATP--------------LPKGAPTTP 1060
                   P+  P P    TPP+  T  +    PA  P              L    P +P
Sbjct: 157  SQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASP 216

Query: 1061 AATLPSPKGG--PATPSLKGAPTPPAATPPSPKGGPATPS----------PKGAPMPPAA 1108
            + +  +  G    ++PS   +   PA     P G   +P           P G P PP++
Sbjct: 217  SGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSS 276


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score =  305 bits (780), Expect = 4e-82
 Identities = 316/1051 (30%), Positives = 428/1051 (40%), Gaps = 128/1051 (12%)

Query: 712  PSPQNTCAPLATLVLAPEIPKSVPSPS---------LPPAGTPPGTKKVDGISHTSALAP 762
            P  ++ CA +     +P   K  P PS            +  PP  KK   +  +  +  
Sbjct: 57   PDYESFCAEVHNPT-SPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITE 115

Query: 763  VASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIG 822
              S  +    E S +S+++SS  T+  +  S +        +  +    K +     P  
Sbjct: 116  EHSVSEN--QESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKP-- 171

Query: 823  NLSSPVSPV--EASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTL 880
               +P  PV  EA    +N      + D+  T H+    SPK     +   P++P+  +L
Sbjct: 172  ---TPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPK----ITTAKPINPRP-SL 223

Query: 881  PPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPK--GIPASPSPKG 938
            PP  + T    +L   KE   T   K+    +  +S+  K + T A +   I  + +   
Sbjct: 224  PPN-SDTSKETSLTVNKE--TTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 280

Query: 939  APTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG 998
            APT      P+PK    T  P    TP   TP +PK   +T       TP   TP + K 
Sbjct: 281  APTSKVLAKPTPKAETTTKGPALT-TPKEPTPTTPKEPAST-------TPKEPTPTTIKS 332

Query: 999  GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPT 1058
             P TP  + APT     P +PK  PA T   + A T P    P+    PA T   K APT
Sbjct: 333  APTTPK-EPAPTTTKSAPTTPK-EPAPTTTKEPAPTTPKEPAPTTTKEPAPT-TTKSAPT 389

Query: 1059 TPAATLPS--PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGG 1116
            TP    P+   K  P TP      TP   TP +PK        + AP      P +PK  
Sbjct: 390  TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK--------EPAPTTKEPAPTTPKEP 441

Query: 1117 LATPPHKGAPTTP-AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175
              T P K APTTP    P +PK    T   + +PTTP    P+      T   + APTT 
Sbjct: 442  APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 501

Query: 1176 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP-AATPPSPKGGLAT 1234
             + P +PK    T + + APTTP    P       T   K APTTP    P +PK    T
Sbjct: 502  KSAPTTPKEPSPTTTKEPAPTTPKEPAP-------TTPKKPAPTTPKEPAPTTPKEPAPT 554

Query: 1235 PSPKGAPTTP-AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAP-NPAVV 1292
             + K APTTP    P +PK    T P K  PT P    P       T P K AP  P  +
Sbjct: 555  TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP-------TTPEKPAPTTPEEL 607

Query: 1293 TPPSPKGGPATSPPKGAP-TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPA 1351
             P +P+    T+P + AP TP AA P +PK    T P + APT    TP  P   PT P 
Sbjct: 608  APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT----TPKEP--APTTPK 661

Query: 1352 TTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSP-AVIPL 1410
             T  +    T P++ + P P   TP       + P + K   +    K  PT+P    P 
Sbjct: 662  ETAPTTPKGTAPTTLKEPAP--TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 719

Query: 1411 SPKK-APATPVTREGAATPSKG----DLTPPAVTPVSLKKAPATSAP---KGGPATPSSK 1462
            +PK+ AP TP  +E A T  KG     L  PA T    K AP   AP   KG  +T S K
Sbjct: 720  TPKEPAPTTP--KEPAPTTPKGTAPTTLKEPAPT-TPKKPAPKELAPTTTKGPTSTTSDK 776

Query: 1463 GDPTLPAVTPPSPKEPPAPKQVATSSSPKK-APATPAPMGAPTLPAVIPSSPKEVPATPS 1521
              PT P  T P+  + PAP      ++PKK AP TP      T     P++ KE P T  
Sbjct: 777  PAPTTPKETAPTTPKEPAP------TTPKKPAPTTPETPPPTTSEVSTPTTTKE-PTT-- 827

Query: 1522 SRRDPIAPTATLLSKKTPATL--APKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEA 1579
              + P   T  L ++ TP  L  +PKE  +P         KTPA   P E   T   K  
Sbjct: 828  IHKSPDESTPELSAEPTPKALENSPKEPGVPTT-------KTPAATKP-EMTTTAKDKTT 879

Query: 1580 SSPPAVTPSTYKGAPS-PKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP--------AT 1630
                  TP T   AP   KE       T+ S   A T    +  + +  P         T
Sbjct: 880  ERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTT 939

Query: 1631 PAPKGTPTSPPVTPSSLKDSP---TSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVA 1687
             APK T T   +T + + + P     P        AT P+  K   A K PT+ K+    
Sbjct: 940  LAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK---- 995

Query: 1688 PAPESTPIITAPTRKGPQTKKSSATSPPICP 1718
              P++ P +  P +  P  +K ++T P + P
Sbjct: 996  --PKTMPRVRKP-KTTPTPRKMTSTMPELNP 1023



 Score =  285 bits (728), Expect = 4e-76
 Identities = 278/915 (30%), Positives = 356/915 (38%), Gaps = 131/915 (14%)

Query: 735  PSPSLPP-AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADS 793
            P PSLPP + T   T        T       ++ K+  T+  G   T S+K T +    S
Sbjct: 219  PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTD--GKEKTTSAKETQSIEKTS 276

Query: 794  PSPLG----VSVSPQTKRPPTKKGSA--GPDTPIGNLSSPVSPVEASFLPENSLSFQGSK 847
               L     V   P  K   T KG A   P  P     +P +P E +       +    K
Sbjct: 277  AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP-----TPTTPKEPASTTPKEPTPTTIK 331

Query: 848  DSPATTHSPTPPSPKGAPT----PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903
             +P T   P P + K APT    P+  T   P   T  PKE P P+    P P    + P
Sbjct: 332  SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT--PKE-PAPTTTKEPAPTTTKSAP 388

Query: 904  APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963
               + PA     ++PKK   T   +  P +P      TP    P + +  P TP    AP
Sbjct: 389  TTPKEPA----PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP-AP 443

Query: 964  TPPAATPPSPKGGPATPSPKG-APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS 1022
            T P    P+    PA  +PK  APT      P+    PA  + K APT      P+   S
Sbjct: 444  TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 503

Query: 1023 PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS-PKGGPATPSLKGAPT 1081
               TP     +T     P +PK  PA T   K APTTP    P+ PK    T + K APT
Sbjct: 504  APTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 562

Query: 1082 PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA-TPPSPKGGL 1140
                TP  P   P TP       P   TP +P+    T P K APTTP    P +P+   
Sbjct: 563  ----TPKEP--APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 616

Query: 1141 ATPPPKGAPTTP-AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1199
             T P + APTTP AA P +PK    T P + APTTP                + APTTP 
Sbjct: 617  PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK---------------EPAPTTPK 661

Query: 1200 ATPPS-PKGGLATPSPKGAPTTPAATPPSPKGGLATPSP------KGAPTTPAATPPS-P 1251
             T P+ PKG   T   + APTTP    P       T  P      K APTTP  T P+ P
Sbjct: 662  ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 721

Query: 1252 KGGPATPPPKGAPTPPAATPPS-LKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP 1310
            K    T P + APT P  T P+ LK    T P K  P P  + P + KG  +T+  K AP
Sbjct: 722  KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK--PAPKELAPTTTKGPTSTTSDKPAP 779

Query: 1311 TPPAATPPS-PKGSPGTPPPKGAPTPPAVTPP--SPKGTPTLPA--TTPSSKGGPTTPSS 1365
            T P  T P+ PK    T P K APT P   PP  S   TPT     TT       +TP  
Sbjct: 780  TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 839

Query: 1366 KEGPTPPAA--TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATP-VTR 1422
               PTP A   +P   G P    P+  + P + +   D T+   +  +P+   A P +T+
Sbjct: 840  SAEPTPKALENSPKEPGVPTTKTPAATK-PEMTTTAKDKTTERDLRTTPETTTAAPKMTK 898

Query: 1423 EGAATPSKG------------------DLTPPAVTPV----------SLKKAPATSAPKG 1454
            E A T  K                   D TP  +T +          + KK   T+    
Sbjct: 899  ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMN 958

Query: 1455 GPA-TPSSKGDPTLPAVTPPSPKEPP-APKQVATSSSPKKAPATPAPMGAPTLPAVIPSS 1512
             P  T   K   T    T P P++P  APK+  ++  PK  P    P   PT        
Sbjct: 959  KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPT-------- 1010

Query: 1513 PKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPA 1572
                P   +S    + PT+ +       T  P +                  P  K    
Sbjct: 1011 ----PRKMTSTMPELNPTSRIAEAMLQTTTRPNQT-----------------PNSKLVEV 1049

Query: 1573 TPSSKEASSPPAVTP 1587
             P S++A      TP
Sbjct: 1050 NPKSEDAGGAEGETP 1064



 Score =  259 bits (661), Expect = 2e-68
 Identities = 305/1086 (28%), Positives = 403/1086 (37%), Gaps = 143/1086 (13%)

Query: 477  PTSPAALVMAPVAPKEPSTQVATTLRIPVSP------PLPDPEDL--------KNLPSSV 522
            PTSP +   AP       T  +TT R P  P       + + E++            SS 
Sbjct: 69   PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 128

Query: 523  LVKFPTQKDLQTVPASLEGAPFSPAQAGL--------TTKKDPTVLPLV---QAAPKNSP 571
                 +   ++ + +S   A     Q  L         TKK PT  P V     +  ++ 
Sbjct: 129  SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNG 188

Query: 572  SFQ------STSSSPEIPLSPEATLAKKSLGEP-LPIGKPASSMTSPLGVNSSASV---- 620
             F+      ST+   ++  SP+ T AK     P LP     S  TS L VN   +V    
Sbjct: 189  DFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETS-LTVNKETTVETKE 247

Query: 621  ----IKTDSYAGPDSAGPLLKSSLITPT----VAAFPLESADPAGVAPTTAKGTSTYTTT 672
                 K  S  G +      ++  I  T    +A      A P   A TT KG +  TT 
Sbjct: 248  TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA-LTTP 306

Query: 673  ASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNT-CAPLATLVLAPEIP 731
              P    T    P +   KE T TT+   PT     P  P+P  T  AP      AP   
Sbjct: 307  KEP--TPTTPKEPASTTPKEPTPTTIKSAPTT----PKEPAPTTTKSAPTTPKEPAPTTT 360

Query: 732  KSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLA 791
            K  P+P+ P    P  TK+           P  ++ K  PT     + T   K       
Sbjct: 361  KE-PAPTTPKEPAPTTTKE-----------PAPTTTKSAPTTPKEPAPTTPKK------- 401

Query: 792  DSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPA 851
              P+P     +P+   P T K    P TP     +P +   A   P+        K +P 
Sbjct: 402  --PAP----TTPKEPAPTTPK-EPTPTTP--KEPAPTTKEPAPTTPKEPAPTAPKKPAPT 452

Query: 852  TTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPAL 911
            T   P P +PK  P P+     SP      PKE    +  + P   + PA    K AP  
Sbjct: 453  TPKEPAPTTPK-EPAPTTTKEPSP----TTPKEPAPTTTKSAPTTTKEPAPTTTKSAP-- 505

Query: 912  SMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK----GGPATPSPKWAPTPPA 967
                ++PK+   T   +  P +P      TP    P +PK      P  P+P     P  
Sbjct: 506  ----TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 561

Query: 968  ATPPSPKGGPATPSPKGAPTPPAATPPSP-KGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026
             TP  P   P TP      TP   TP +P K  P TP      TP  + P +P+     T
Sbjct: 562  TTPKEP--APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 619

Query: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT 1086
            P     +TP AA P +PK  PA T   + APTTP       +  P TP  + APT P  T
Sbjct: 620  PEEPAPTTPKAAAPNTPK-EPAPTTPKEPAPTTP------KEPAPTTPK-ETAPTTPKGT 671

Query: 1087 PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAAT-PPSPKGGLATPPP 1145
             P+    PA  +PK  P P    P + K   +T   K APTTP  T P +PK    T P 
Sbjct: 672  APTTLKEPAPTTPK-KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 730

Query: 1146 KGAPTTPAATPPSP-KGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT-PP 1203
            + APTTP  T P+  K    T P K AP   A  P + KG  +T S K APTTP  T P 
Sbjct: 731  EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA--PTTTKGPTSTTSDKPAPTTPKETAPT 788

Query: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP----------PSPKG 1253
            +PK    T   K APTTP  TPP     ++TP+    PTT   +P          P+PK 
Sbjct: 789  TPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 847

Query: 1254 GPATPPPKGAPT--PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP------ATSP 1305
               +P   G PT   PAAT P +     T   K        TP +    P      AT+ 
Sbjct: 848  LENSPKEPGVPTTKTPAATKPEM---TTTAKDKTTERDLRTTPETTTAAPKMTKETATTT 904

Query: 1306 PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLP--ATTPSSKGGPTTP 1363
             K   +   AT      +          T    T  +PK T T     TT        T 
Sbjct: 905  EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA 964

Query: 1364 SSKEGPTPPAATPSHKGGPAMTP------PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA 1417
              K+  T   AT      P   P        PK  P +  PK  PT   +    P+  P 
Sbjct: 965  KPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 1024

Query: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477
            + +      T ++ + TP +       K+      +G       +    +P VTP     
Sbjct: 1025 SRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYL 1084

Query: 1478 PPAPKQ 1483
            P  P Q
Sbjct: 1085 PRVPNQ 1090



 Score =  239 bits (610), Expect = 2e-62
 Identities = 322/1179 (27%), Positives = 428/1179 (36%), Gaps = 216/1179 (18%)

Query: 257  SPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSS 316
            +P +P S S K P  PP+  S + +S    T+ +    PN      +     +   H  S
Sbjct: 68   NPTSPPS-SKKAP--PPSGASQTIKS----TTKRSPKPPNKKKTKKVIESEEITEEH--S 118

Query: 317  FGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPV 376
                Q    +  S+ S  T++ I    +S      + R +   L  ++     T      
Sbjct: 119  VSENQESSSSSSSSSSSSTIRKIKSSKNSA-----ANRELQKKLKVKDNKKNRTKKKPTP 173

Query: 377  VAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQ--MPVS 434
              P VD+  S + +      G   V T    S T    + +SP  T   P+  +  +P +
Sbjct: 174  KPPVVDEAGSGLDN------GDFKVTTP-DTSTTQHNKVSTSPKITTAKPINPRPSLPPN 226

Query: 435  SVGT--TPLVVTNPCTIAAAPTTTFEVATCVS---PPMSSGPISNIEPTS-----PAALV 484
            S  +  T L V    T+    TTT    T         S+    +IE TS     P + V
Sbjct: 227  SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 286

Query: 485  MAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPF 544
            +A   PK  +T     L  P  P    P++    P+S   K PT       P +++ AP 
Sbjct: 287  LAKPTPKAETTTKGPALTTPKEPTPTTPKE----PASTTPKEPT-------PTTIKSAPT 335

Query: 545  SPAQ-AGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGK 603
            +P + A  TTK  PT        PK      +   +P  P  P  T  K+          
Sbjct: 336  TPKEPAPTTTKSAPTT-------PKEPAPTTTKEPAPTTPKEPAPTTTKE---------- 378

Query: 604  PASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTA 663
            PA + T                           KS+  TP   A       P   APTT 
Sbjct: 379  PAPTTT---------------------------KSAPTTPKEPA----PTTPKKPAPTTP 407

Query: 664  KGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLAT 723
            K  +  TT   P             P +    T  P   T  E  P AP           
Sbjct: 408  KEPAP-TTPKEP---------TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP-------- 449

Query: 724  LVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASS 783
               AP  PK  P+P+ P    P  TK+    S T+   P  ++ K  PT     + T + 
Sbjct: 450  ---APTTPKE-PAPTTPKEPAPTTTKEP---SPTTPKEPAPTTTKSAPTTTKEPAPTTTK 502

Query: 784  KGTLTYLADSPSPLGVSVSPQTKRP-PTKKGSAGPDTPIGNLSSPVSPVE-ASFLPENSL 841
                T    SP+         TK P PT      P TP     +P +P E A   P+   
Sbjct: 503  SAPTTPKEPSPT--------TTKEPAPTTPKEPAPTTP--KKPAPTTPKEPAPTTPK--- 549

Query: 842  SFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPA 901
                 + +P TT  P P +PK  P P+     +P   T P K TPT         K  P 
Sbjct: 550  -----EPAPTTTKKPAPTTPK-EPAPTTPKETAP---TTPKKLTPTTP------EKLAPT 594

Query: 902  TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKW 961
            TP  K AP      ++P++   T   +  P +P      TP AA P +PK     P+P  
Sbjct: 595  TP-EKPAP------TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK----EPAPTT 643

Query: 962  APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG 1021
               P   TP  P   P TP  + APT P  T P+    PA  +PK  P P  + P + K 
Sbjct: 644  PKEPAPTTPKEP--APTTPK-ETAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTTK- 698

Query: 1022 SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPT 1081
             P +T   K A T P  T P+    PA T   + APTTP  T P+    PA P+    P 
Sbjct: 699  EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA-PTTPKKPA 757

Query: 1082 PPAATPPSPKGGPATPSPKGAPMPPAAT-PPSPKGGLATPPHKGAPTTPAATPPSPKGGL 1140
            P    P + KG  +T S K AP  P  T P +PK    T P K APTTP  TPP     +
Sbjct: 758  PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEV 816

Query: 1141 ATPPPKGAPTTPAATP----------PSPKGGLATPPPKGAPT--TPAATPPSPKGGLAT 1188
            +TP     PTT   +P          P+PK    +P   G PT  TPAAT P       T
Sbjct: 817  STPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM---TTT 873

Query: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248
               K        TP +      T +PK    T   T  + +  +   + +   TT   T 
Sbjct: 874  AKDKTTERDLRTTPET-----TTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 928

Query: 1249 P--SPKGGPATPPPKGAPTPPAATPPSL--KGGLATPPHKGAPNPAVVTPPSPKGGPATS 1304
            P         T  PK   T    T   +  K      P   A N    TP   K      
Sbjct: 929  PFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK------ 982

Query: 1305 PPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP------------TLPAT 1352
             P  AP  P +T   PK  P    PK  PTP  +T   P+  P            T P  
Sbjct: 983  -PTKAPKKPTST-KKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQ 1040

Query: 1353 TPSSKGGPTTPSSK-----EGPTPPAATPSHKGGPAMTP 1386
            TP+SK     P S+     EG TP      H   P +TP
Sbjct: 1041 TPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTP 1079



 Score =  225 bits (574), Expect = 3e-58
 Identities = 265/973 (27%), Positives = 363/973 (37%), Gaps = 152/973 (15%)

Query: 981  SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP 1040
            +P   P+   A PPS        + K +P PP                    S    ++ 
Sbjct: 68   NPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS 127

Query: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100
             S   S ++T     +    AA     K       LK        T   P   P      
Sbjct: 128  SSSSSSSSSTIRKIKSSKNSAANRELQK------KLKVKDNKKNRTKKKPTPKPPVVDEA 181

Query: 1101 GAPMP----PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156
            G+ +        TP +     +T  H    T+P  T   P     + PP    +   +  
Sbjct: 182  GSGLDNGDFKVTTPDT-----STTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLT 236

Query: 1157 PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1216
             + +  + T       TT      S  G   T S K   +              T +   
Sbjct: 237  VNKETTVETKE-----TTTTNKQTSTDGKEKTTSAKETQSIEK-----------TSAKDL 280

Query: 1217 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG 1276
            APT+     P+PK    T  P         TP  P   P TP    + TP   TP ++K 
Sbjct: 281  APTSKVLAKPTPKAETTTKGPA------LTTPKEPT--PTTPKEPASTTPKEPTPTTIKS 332

Query: 1277 GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP 1336
               T P + AP      P +PK    T+  + APT P    P+    P     K APT P
Sbjct: 333  A-PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 391

Query: 1337 AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP 1396
                P+   TP  PA T   +  PTTP      TP    P+ K     TP  P   P  P
Sbjct: 392  KEPAPT---TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP--APTAP 446

Query: 1397 SPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGP 1456
                  T     P +PK+ PA   T+E + T      TP    P + K AP T+     P
Sbjct: 447  KKPAPTTPKEPAPTTPKE-PAPTTTKEPSPT------TPKEPAPTTTKSAPTTTKE---P 496

Query: 1457 ATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEV 1516
            A  ++K  PT P    P+  + PAP            P  PAP   P  PA  P++PKE 
Sbjct: 497  APTTTKSAPTTPKEPSPTTTKEPAPT----------TPKEPAPT-TPKKPA--PTTPKE- 542

Query: 1517 PATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE-APATPS 1575
            PA P++ ++P APT T    K PA   PKE               PA  TPKE AP TP 
Sbjct: 543  PA-PTTPKEP-APTTT----KKPAPTTPKE---------------PAPTTPKETAPTTPK 581

Query: 1576 SKEASSPPAVTPST-YKGAPSPKELLIPPAVTSPSP----KEAPTPPAVTPPSPEKGPAT 1630
                ++P  + P+T  K AP+  E L P     P+P    + APT P    P+  K PA 
Sbjct: 582  KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 641

Query: 1631 PAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAP 1690
              PK    + P  P+     PT+P         T P   KG      PT LKE    PAP
Sbjct: 642  TTPKEPAPTTPKEPA-----PTTPKE-------TAPTTPKGT----APTTLKE----PAP 681

Query: 1691 ESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQ------KD 1744
             +TP   AP    P T K   ++    P P+   G+  P +   PAP  P +      K 
Sbjct: 682  -TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT-APTTPKEPAPTTPKEPAPTTPKG 739

Query: 1745 SSKTAKGKDASHSPKGP----LAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSL 1800
            ++ T   + A  +PK P    LAP  +K  T  T+       PK  + +    P+P  + 
Sbjct: 740  TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP--TT 797

Query: 1801 PLAPSP-VPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVL 1859
            P  P+P  P  PP      S+P    E  +   +P   DE  P +  EP          L
Sbjct: 798  PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP---DESTPELSAEPT------PKAL 848

Query: 1860 VNMPTPKSAGIP-VPTPSAKQP-VTKNNKGSGTESD------SDESVPEL--EEQDSTQA 1909
             N  +PK  G+P   TP+A +P +T   K   TE D      +  + P++  E   +T+ 
Sbjct: 849  EN--SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 906

Query: 1910 TTQQAQLAAAAEI 1922
            TT+    A   ++
Sbjct: 907  TTESKITATTTQV 919



 Score =  209 bits (532), Expect = 2e-53
 Identities = 271/949 (28%), Positives = 353/949 (37%), Gaps = 140/949 (14%)

Query: 1080 PTPPAATPPSPKGGPATPSPKGAPMPP--AATPPSPKGGLATPPHKGAPTTPAATPPSPK 1137
            P+   A PPS        + K +P PP    T    +    T  H  +    +++  S  
Sbjct: 73   PSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSS 132

Query: 1138 GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP----------KGGLA 1187
               +T     +    AA     K  L     K   T    TP  P           G   
Sbjct: 133  SSSSTIRKIKSSKNSAANRELQKK-LKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFK 191

Query: 1188 TPSPKGAPTTPAATPPSPKGGLATP-SPKGAPTTPAATPPSPKGGLA-----TPSPKGAP 1241
              +P  + T       SPK   A P +P+  P+ P  +  S +  L      T   K   
Sbjct: 192  VTTPDTSTTQHNKVSTSPKITTAKPINPR--PSLPPNSDTSKETSLTVNKETTVETKETT 249

Query: 1242 TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP 1301
            TT   T  S  G   T   K   +    +   L           AP   V+  P+PK   
Sbjct: 250  TTNKQT--STDGKEKTTSAKETQSIEKTSAKDL-----------APTSKVLAKPTPKAET 296

Query: 1302 ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361
             T  P    TP   TP +PK    T P +  PT     P +PK     PA T ++K  PT
Sbjct: 297  TTKGP-ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKE----PAPT-TTKSAPT 350

Query: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV-IPLSPKK-APATP 1419
            TP      T     P+    PA   P+  + PA  + K  PT+P    P +PKK AP TP
Sbjct: 351  TPKEPAPTTTKEPAPTTPKEPA---PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 407

Query: 1420 VTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV-TPPSPKEP 1478
              +E A T  K         P    K PA + PK    T   K  PT P    P +PKEP
Sbjct: 408  --KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 465

Query: 1479 PAPKQVATSSSPKKAPATPAPMGAPTL---PAVIPSSPKEVPATPSSRRDPIAPTATLLS 1535
                    S +  K PA      APT    PA  P++ K  P TP   ++P +PT T   
Sbjct: 466  APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA--PTTTKSAPTTP---KEP-SPTTT--- 516

Query: 1536 KKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE-APATPSSKEASSPPAVTPSTYKGAP 1594
             K PA   PKE    PA T P   K PA  TPKE AP TP        PA T +      
Sbjct: 517  -KEPAPTTPKE----PAPTTP---KKPAPTTPKEPAPTTPKE------PAPTTTKKPAPT 562

Query: 1595 SPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP----PVTPSS-LKD 1649
            +PKE    PA T+P      TP  +TP +PEK   T   K  PT+P    P TP      
Sbjct: 563  TPKE----PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 618

Query: 1650 SPTSPASVTCKMGA--TVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTR-KG--P 1704
            +P  PA  T K  A  T  + +   P +  PT  KE    PAP +TP  TAPT  KG  P
Sbjct: 619  TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE----PAP-TTPKETAPTTPKGTAP 673

Query: 1705 QTKKSSATSPPICPDPS--AKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPL 1762
             T K  A + P  P P   A   +K P ST    P     K ++ T   + A  +PK P 
Sbjct: 674  TTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP- 732

Query: 1763 APPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPV--PTLPPKQQFLPSS 1820
            AP   K + P T        P P +      P  P    LAP+    PT     +  P++
Sbjct: 733  APTTPKGTAPTTLKE-----PAPTT------PKKPAPKELAPTTTKGPTSTTSDKPAPTT 781

Query: 1821 PGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQP 1880
            P        K  AP    E  P  P +P              P P ++ +  PT + K+P
Sbjct: 782  P--------KETAPTTPKEPAPTTPKKPAP-------TTPETPPPTTSEVSTPT-TTKEP 825

Query: 1881 VTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQ------LAAAAEIDEEPVSKAKQSR 1934
             T            DES PEL  + + +A     +          A    E  + AK   
Sbjct: 826  TT-------IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 878

Query: 1935 SEKKARKA-MSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDT 1982
            +E+  R    +     ++T  T  T  K+       T   V  +   DT
Sbjct: 879  TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDT 927



 Score =  166 bits (420), Expect = 2e-40
 Identities = 268/1120 (23%), Positives = 382/1120 (34%), Gaps = 174/1120 (15%)

Query: 154  PPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVP 213
            PP+   +PP    +++    T  +P  P++ KT    + SE +                 
Sbjct: 72   PPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTK-KVIESEEITEE-------------- 116

Query: 214  YHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPP 273
             H V+      S  +S   ++    +  +     +  +   L    N  + + K P   P
Sbjct: 117  -HSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKP 175

Query: 274  AALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSD 333
              +  +   L       K   P+T                                  S 
Sbjct: 176  PVVDEAGSGLD--NGDFKVTTPDT----------------------------------ST 199

Query: 334  PTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVV----APSVDKGPST-- 387
                 +S     T A   + R  +PP    ++    TV     V      + +K  ST  
Sbjct: 200  TQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDG 259

Query: 388  -ISSITCSPSGSLNVATSFSLSPTTSLILKSSPNA--TYHYPLVA-------QMPVSSVG 437
               + +   + S+   ++  L+PT+ ++ K +P A  T   P +          P     
Sbjct: 260  KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS 319

Query: 438  TTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQV 497
            TTP   T P TI +APTT  E A   +    S P +  EP        AP  PKEP+   
Sbjct: 320  TTPKEPT-PTTIKSAPTTPKEPAPTTT---KSAPTTPKEPAPTTTKEPAPTTPKEPA--- 372

Query: 498  ATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDP 557
                  P +   P P   K+ P++     PT           + AP +P +   TT K+P
Sbjct: 373  ------PTTTKEPAPTTTKSAPTTPKEPAPT--------TPKKPAPTTPKEPAPTTPKEP 418

Query: 558  TVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSS 617
            T        PK  P+  +   +P  P  P  T  KK    P P      + T+P     +
Sbjct: 419  T-----PTTPK-EPAPTTKEPAPTTPKEPAPTAPKK----PAPTTPKEPAPTTP--KEPA 466

Query: 618  ASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFL 677
             +  K  S   P    P    S   PT    P         APTT K   T     SP  
Sbjct: 467  PTTTKEPSPTTPKEPAPTTTKS--APTTTKEP---------APTTTKSAPTTPKEPSP-- 513

Query: 678  EGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSP 737
              T +  P     KE   TT P  P  +     AP+     AP  T   AP  PK  P+P
Sbjct: 514  --TTTKEPAPTTPKEPAPTT-PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-PAP 569

Query: 738  SLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPL 797
            + P    P   KK+   +    LAP  +  K  PT     + T   + T T   + P+P 
Sbjct: 570  TTPKETAPTTPKKLTPTT-PEKLAP-TTPEKPAPTTPEELAPTTPEEPTPT-TPEEPAP- 625

Query: 798  GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVE-ASFLPENSLSFQGSKDSPATTHSP 856
                +P+   P T K  A P TP     +P +P E A   P+ +        +P T   P
Sbjct: 626  ---TTPKAAAPNTPKEPA-PTTP--KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 679

Query: 857  TPPSPKG------APT----PSAVT-----PLSPKGVTLPPKETPTPSVVNLPFPKEGPA 901
             P +PK       APT    P++ T     P +PKG      + P P+    P P     
Sbjct: 680  APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 739

Query: 902  T-PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK 960
            T P   + PA +       K  A    KG  ++ S K APT P  T P+    PA  +PK
Sbjct: 740  TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK 799

Query: 961  W-APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAV-TPPS 1018
              APT P  TPP      +TP+    PT    +P       +TP     PTP A+   P 
Sbjct: 800  KPAPTTP-ETPPPTTSEVSTPTTTKEPTTIHKSPDE-----STPELSAEPTPKALENSPK 853

Query: 1019 PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG 1078
              G P         +  PAAT P    +       +   TTP  T  +PK    T +   
Sbjct: 854  EPGVP--------TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTE 905

Query: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138
              T    T  + +   +T +    P        +      T   K   TT     P    
Sbjct: 906  KTTESKITATTTQ-VTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPE--- 961

Query: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198
               T  PK   T   AT P P+       P  AP  P +T   PK       PK  PT  
Sbjct: 962  --ETAKPKDRATNSKATTPKPQ------KPTKAPKKPTST-KKPKTMPRVRKPKTTPTPR 1012

Query: 1199 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1238
              T   P+    +   +    T      +P   L   +PK
Sbjct: 1013 KMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPK 1052



 Score =  144 bits (363), Expect = 9e-34
 Identities = 172/675 (25%), Positives = 236/675 (34%), Gaps = 91/675 (13%)

Query: 1317 PPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATP 1376
            P SP  S   PPP GA             + T+ +TT  S   P    +K+       T 
Sbjct: 69   PTSPPSSKKAPPPSGA-------------SQTIKSTTKRSPKPPNKKKTKKVIESEEITE 115

Query: 1377 SHKGGP----AMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK--------------KAPAT 1418
             H        + +  S      I   K    S A   L  K                P  
Sbjct: 116  EHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKP 175

Query: 1419 PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP 1478
            PV  E  +    GD         + +    +++PK   A P +      P++ P S    
Sbjct: 176  PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR----PSLPPNSDTSK 231

Query: 1479 PAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKT 1538
                 V   ++ +    T       T      +S KE  +   +    +APT+ +L+K T
Sbjct: 232  ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT 291

Query: 1539 PA--TLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAP-S 1595
            P   T     AL  P    P+  K PA  TPKE   T      ++P    P+T K AP +
Sbjct: 292  PKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 351

Query: 1596 PKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP----PVTPSS-LKDS 1650
            PKE   P   T+  P  APT P    P+  K PA    K  PT+P    P TP      +
Sbjct: 352  PKE---PAPTTTKEP--APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 406

Query: 1651 PTSPASVTCKMGA-TVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKS 1709
            P  PA  T K    T P+       +  PT  KE   AP     P  T P    P T K 
Sbjct: 407  PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE--PAPTAPKKPAPTTPKEPAPTTPKE 464

Query: 1710 SA------TSPPICPDPSAKNGSKGPLSTVAPAPLL-----PVQKDSSKTAKGKDASHSP 1758
             A       SP    +P+       P +T  PAP          K+ S T   + A  +P
Sbjct: 465  PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 524

Query: 1759 KGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSP------VPTLPP 1812
            K P AP   K   P T        PK  + + +  P+P  + P  P+P       PT P 
Sbjct: 525  KEP-APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP--TTPKEPAPTTPKETAPTTPK 581

Query: 1813 KQQFLPSSP-GLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIP 1871
            K    P++P  L   +P KP AP   +EL P  P E               PTP +   P
Sbjct: 582  K--LTPTTPEKLAPTTPEKP-APTTPEELAPTTPEE---------------PTPTTPEEP 623

Query: 1872 VP-TPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKA 1930
             P TP A  P T       T  +   + P+     + + T        A    +EP    
Sbjct: 624  APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 683

Query: 1931 KQSRSEKKARKAMSK 1945
             +  + K+     +K
Sbjct: 684  PKKPAPKELAPTTTK 698



 Score =  135 bits (341), Expect = 3e-31
 Identities = 228/952 (23%), Positives = 330/952 (34%), Gaps = 158/952 (16%)

Query: 66   PFPSP-------STIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAA--- 115
            P P P       S + +   +V  P +S+     + T+P+  T  P    P + P +   
Sbjct: 171  PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 230

Query: 116  ----------LALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFP----PNLLTSP 161
                        + +     T K T +        A    S++K+SA        +L  P
Sbjct: 231  KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 290

Query: 162  -PSVAVAESGSVITLS---APIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCV 217
             P       G  +T      P  P EP +   K P+            P  + + P    
Sbjct: 291  TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT------------PTTIKSAP---T 335

Query: 218  TPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALS 277
            TP     +   S P TTP       + +   TT       P+ P   + K P       +
Sbjct: 336  TPKEPAPTTTKSAP-TTPKEPAPTTTKEPAPTT-------PKEPAPTTTKEPAPTTTKSA 387

Query: 278  LSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVK 337
             +T   P  T+ +K A P TP                          +  P+   +PT  
Sbjct: 388  PTTPKEPAPTTPKKPA-PTTPK-------------------------EPAPTTPKEPTPT 421

Query: 338  TISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSG 397
            T      +T    P+  +   P P+  +    T    P  AP+  K P+  ++   SP+ 
Sbjct: 422  TPKEPAPTT--KEPAPTTPKEPAPTAPKKPAPTTPKEP--APTTPKEPAPTTTKEPSPT- 476

Query: 398  SLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTF 457
                 T    +PTT+   KS+P  T      A     S  TTP   +   T   APTT  
Sbjct: 477  -----TPKEPAPTTT---KSAPTTTKE---PAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 525

Query: 458  EVATCV------SPPMSSGPISNIEPTSPAALVMAPVAPKEPS----TQVATTLRIPVSP 507
            E A         + P    P +  EP        AP  PKEP+     + A T    ++P
Sbjct: 526  EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 585

Query: 508  PLPD------PEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLP 561
              P+      PE  K  P++     PT  +  T     E AP +P  A   T K+P    
Sbjct: 586  TTPEKLAPTTPE--KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTT 643

Query: 562  LVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPI--GKPASSMTSPLGVNSSAS 619
              + AP        T+     P +P+ T A  +L EP P    KPA    +P       +
Sbjct: 644  PKEPAPTTPKEPAPTTPKETAPTTPKGT-APTTLKEPAPTTPKKPAPKELAP-------T 695

Query: 620  VIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEG 679
              K  +    D   P        PT    P  +  P   APTT KGT+  T      L+ 
Sbjct: 696  TTKEPTSTTCDKPAPTTPKG-TAPTTPKEPAPTT-PKEPAPTTPKGTAPTT------LKE 747

Query: 680  TVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSL 739
                 PK    KE   TT    PT++ +   AP+     AP      AP  PK  P+P+ 
Sbjct: 748  PAPTTPKKPAPKELAPTTTK-GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK-PAPTT 805

Query: 740  PPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGV 799
            P    PP T +V   + T     +  SP E   E        S++ T   L +SP   GV
Sbjct: 806  PET-PPPTTSEVSTPTTTKEPTTIHKSPDESTPE-------LSAEPTPKALENSPKEPGV 857

Query: 800  SVSPQTKRPPTKKGSAGP------------DTPIGNLSSPVSPVEASFLPENSLSFQGSK 847
               P TK P   K                  TP    ++P    E +   E +   + + 
Sbjct: 858  ---PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITA 914

Query: 848  DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP---ATPA 904
             +   T + T  +     T    T L+PK VT   K   T  ++N P     P   AT +
Sbjct: 915  TTTQVTSTTTQDTTPFKITTLKTTTLAPK-VTTTKKTITTTEIMNKPEETAKPKDRATNS 973

Query: 905  PKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT 956
                P     + +PKK  +T  PK +P    PK  PTP   T   P+  P +
Sbjct: 974  KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTS 1025



 Score =  119 bits (299), Expect = 2e-26
 Identities = 189/790 (23%), Positives = 276/790 (34%), Gaps = 98/790 (12%)

Query: 6    TETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQAS 65
            T+++  T  +   P ++    P   A + T      GP L  P  P P   P   A+   
Sbjct: 269  TQSIEKTSAKDLAPTSKVLAKPTPKAETTTK-----GPALTTPKEPTPTT-PKEPASTTP 322

Query: 66   PFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTF----LPNLIGPPISPAALALASP 121
              P+P+TI S P     P  ++  + P      APT      P     P +P      +P
Sbjct: 323  KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP-APTTTKEPAP 381

Query: 122  MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAP 181
                +   TP   AP      AP + ++ +   P     P      E        AP  P
Sbjct: 382  TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK---EPTPTTPKEPAPTTKEPAPTTP 438

Query: 182  SEPKTNLNKVPSEVVPNPKG--TPSPPCIVSTVPYHCVTPMASIQSGVASLPQTT----P 235
             EP     K P+   P      TP  P   +T      TP     +   S P TT    P
Sbjct: 439  KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 498

Query: 236  TTTLAIASPQVK---DTTISSVLISPQNPGSLSLKGPV-SPPAALSLSTQSLPVVTSSQK 291
            TTT +  +   +    TT      +P+ P   + K P  + P   + +T   P  T+++K
Sbjct: 499  TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 558

Query: 292  TAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPT----VKTISVDHSSTG 347
             A P TP +   +     AP       + + L  T P  L+  T      T   + + T 
Sbjct: 559  PA-PTTPKEPAPTTPKETAPT------TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 611

Query: 348  ASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSL 407
               P+  +   P P+  +         P  AP+  K P+  +    +P+      T    
Sbjct: 612  PEEPTPTTPEEPAPTTPKAAAPNTPKEP--APTTPKEPAPTTPKEPAPT------TPKET 663

Query: 408  SPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFE--VATCVSP 465
            +PTT       P  T    L    P     TTP     P     APTTT E    TC  P
Sbjct: 664  APTT-------PKGTAPTTLKEPAP-----TTP---KKPAPKELAPTTTKEPTSTTCDKP 708

Query: 466  -PMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLR--IPVSPPLPDPEDLKNLPSSV 522
             P +    +   P  PA       AP  P     TTL+   P +P  P P++L    +  
Sbjct: 709  APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 768

Query: 523  LVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQST------ 576
                 + K   T P   E AP +P +   TT K P   P     P  + S  ST      
Sbjct: 769  PTSTTSDKPAPTTPK--ETAPTTPKEPAPTTPKKPA--PTTPETPPPTTSEVSTPTTTKE 824

Query: 577  ---------SSSPEIPLSPEATLAKKSLGEP-LPIGKPASSMTSPLGVNSSASVIKTDSY 626
                      S+PE+   P     + S  EP +P  K  ++    +   +     + D  
Sbjct: 825  PTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLR 884

Query: 627  AGPD--SAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPF---LEGTV 681
              P+  +A P +     T T      E    + +  TT + TST T   +PF      T 
Sbjct: 885  TTPETTTAAPKMTKETATTT------EKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 938

Query: 682  SLAPKNHPVKEGTLTTLPLVPTASENCPV---APSPQNTCAPLATLVLAPEIPKSVPSPS 738
            +LAPK    K+ T+TT  ++    E       A + + T         AP+ P S   P 
Sbjct: 939  TLAPKVTTTKK-TITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPK 997

Query: 739  LPPAGTPPGT 748
              P    P T
Sbjct: 998  TMPRVRKPKT 1007



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 70/280 (25%), Positives = 99/280 (35%), Gaps = 25/280 (8%)

Query: 2   PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
           P    E  P T +E P P       P +   +      +P PT P   +P   + P    
Sbjct: 601 PTTPEELAPTTPEE-PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 659

Query: 62  NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAP---EAPTFLPNLIGPPISPAALAL 118
            + +   +P   A T L+ P P +    A P   AP   + PT        P +P   A 
Sbjct: 660 PKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718

Query: 119 ASPMI-APTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSA 177
            +P   APT   TP   AP      AP ++++ +   P              G   T S 
Sbjct: 719 TTPKEPAPT---TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 775

Query: 178 PIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTT 237
             AP+ PK      P E  P     P+P     T P    TP  +  +   S P TT   
Sbjct: 776 KPAPTTPKETAPTTPKEPAPTTPKKPAP-----TTP---ETPPPT--TSEVSTPTTTKEP 825

Query: 238 TLAIASPQVK------DTTISSVLISPQNPGSLSLKGPVS 271
           T    SP         + T  ++  SP+ PG  + K P +
Sbjct: 826 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 865


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score =  305 bits (780), Expect = 4e-82
 Identities = 316/1051 (30%), Positives = 428/1051 (40%), Gaps = 128/1051 (12%)

Query: 712  PSPQNTCAPLATLVLAPEIPKSVPSPS---------LPPAGTPPGTKKVDGISHTSALAP 762
            P  ++ CA +     +P   K  P PS            +  PP  KK   +  +  +  
Sbjct: 98   PDYESFCAEVHNPT-SPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITE 156

Query: 763  VASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIG 822
              S  +    E S +S+++SS  T+  +  S +        +  +    K +     P  
Sbjct: 157  EHSVSEN--QESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKP-- 212

Query: 823  NLSSPVSPV--EASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTL 880
               +P  PV  EA    +N      + D+  T H+    SPK     +   P++P+  +L
Sbjct: 213  ---TPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPK----ITTAKPINPRP-SL 264

Query: 881  PPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPK--GIPASPSPKG 938
            PP  + T    +L   KE   T   K+    +  +S+  K + T A +   I  + +   
Sbjct: 265  PPN-SDTSKETSLTVNKE--TTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 321

Query: 939  APTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG 998
            APT      P+PK    T  P    TP   TP +PK   +T       TP   TP + K 
Sbjct: 322  APTSKVLAKPTPKAETTTKGPALT-TPKEPTPTTPKEPAST-------TPKEPTPTTIKS 373

Query: 999  GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPT 1058
             P TP  + APT     P +PK  PA T   + A T P    P+    PA T   K APT
Sbjct: 374  APTTPK-EPAPTTTKSAPTTPK-EPAPTTTKEPAPTTPKEPAPTTTKEPAPT-TTKSAPT 430

Query: 1059 TPAATLPS--PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGG 1116
            TP    P+   K  P TP      TP   TP +PK        + AP      P +PK  
Sbjct: 431  TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK--------EPAPTTKEPAPTTPKEP 482

Query: 1117 LATPPHKGAPTTP-AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175
              T P K APTTP    P +PK    T   + +PTTP    P+      T   + APTT 
Sbjct: 483  APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 542

Query: 1176 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP-AATPPSPKGGLAT 1234
             + P +PK    T + + APTTP    P       T   K APTTP    P +PK    T
Sbjct: 543  KSAPTTPKEPSPTTTKEPAPTTPKEPAP-------TTPKKPAPTTPKEPAPTTPKEPAPT 595

Query: 1235 PSPKGAPTTP-AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAP-NPAVV 1292
             + K APTTP    P +PK    T P K  PT P    P       T P K AP  P  +
Sbjct: 596  TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP-------TTPEKPAPTTPEEL 648

Query: 1293 TPPSPKGGPATSPPKGAP-TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPA 1351
             P +P+    T+P + AP TP AA P +PK    T P + APT    TP  P   PT P 
Sbjct: 649  APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT----TPKEP--APTTPK 702

Query: 1352 TTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSP-AVIPL 1410
             T  +    T P++ + P P   TP       + P + K   +    K  PT+P    P 
Sbjct: 703  ETAPTTPKGTAPTTLKEPAP--TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 760

Query: 1411 SPKK-APATPVTREGAATPSKG----DLTPPAVTPVSLKKAPATSAP---KGGPATPSSK 1462
            +PK+ AP TP  +E A T  KG     L  PA T    K AP   AP   KG  +T S K
Sbjct: 761  TPKEPAPTTP--KEPAPTTPKGTAPTTLKEPAPT-TPKKPAPKELAPTTTKGPTSTTSDK 817

Query: 1463 GDPTLPAVTPPSPKEPPAPKQVATSSSPKK-APATPAPMGAPTLPAVIPSSPKEVPATPS 1521
              PT P  T P+  + PAP      ++PKK AP TP      T     P++ KE P T  
Sbjct: 818  PAPTTPKETAPTTPKEPAP------TTPKKPAPTTPETPPPTTSEVSTPTTTKE-PTT-- 868

Query: 1522 SRRDPIAPTATLLSKKTPATL--APKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEA 1579
              + P   T  L ++ TP  L  +PKE  +P         KTPA   P E   T   K  
Sbjct: 869  IHKSPDESTPELSAEPTPKALENSPKEPGVPTT-------KTPAATKP-EMTTTAKDKTT 920

Query: 1580 SSPPAVTPSTYKGAPS-PKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP--------AT 1630
                  TP T   AP   KE       T+ S   A T    +  + +  P         T
Sbjct: 921  ERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTT 980

Query: 1631 PAPKGTPTSPPVTPSSLKDSP---TSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVA 1687
             APK T T   +T + + + P     P        AT P+  K   A K PT+ K+    
Sbjct: 981  LAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK---- 1036

Query: 1688 PAPESTPIITAPTRKGPQTKKSSATSPPICP 1718
              P++ P +  P +  P  +K ++T P + P
Sbjct: 1037 --PKTMPRVRKP-KTTPTPRKMTSTMPELNP 1064



 Score =  285 bits (728), Expect = 4e-76
 Identities = 278/915 (30%), Positives = 356/915 (38%), Gaps = 131/915 (14%)

Query: 735  PSPSLPP-AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADS 793
            P PSLPP + T   T        T       ++ K+  T+  G   T S+K T +    S
Sbjct: 260  PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTD--GKEKTTSAKETQSIEKTS 317

Query: 794  PSPLG----VSVSPQTKRPPTKKGSA--GPDTPIGNLSSPVSPVEASFLPENSLSFQGSK 847
               L     V   P  K   T KG A   P  P     +P +P E +       +    K
Sbjct: 318  AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP-----TPTTPKEPASTTPKEPTPTTIK 372

Query: 848  DSPATTHSPTPPSPKGAPT----PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903
             +P T   P P + K APT    P+  T   P   T  PKE P P+    P P    + P
Sbjct: 373  SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT--PKE-PAPTTTKEPAPTTTKSAP 429

Query: 904  APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963
               + PA     ++PKK   T   +  P +P      TP    P + +  P TP    AP
Sbjct: 430  TTPKEPA----PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP-AP 484

Query: 964  TPPAATPPSPKGGPATPSPKG-APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS 1022
            T P    P+    PA  +PK  APT      P+    PA  + K APT      P+   S
Sbjct: 485  TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 544

Query: 1023 PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS-PKGGPATPSLKGAPT 1081
               TP     +T     P +PK  PA T   K APTTP    P+ PK    T + K APT
Sbjct: 545  APTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 603

Query: 1082 PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA-TPPSPKGGL 1140
                TP  P   P TP       P   TP +P+    T P K APTTP    P +P+   
Sbjct: 604  ----TPKEP--APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 657

Query: 1141 ATPPPKGAPTTP-AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1199
             T P + APTTP AA P +PK    T P + APTTP                + APTTP 
Sbjct: 658  PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK---------------EPAPTTPK 702

Query: 1200 ATPPS-PKGGLATPSPKGAPTTPAATPPSPKGGLATPSP------KGAPTTPAATPPS-P 1251
             T P+ PKG   T   + APTTP    P       T  P      K APTTP  T P+ P
Sbjct: 703  ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 762

Query: 1252 KGGPATPPPKGAPTPPAATPPS-LKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP 1310
            K    T P + APT P  T P+ LK    T P K  P P  + P + KG  +T+  K AP
Sbjct: 763  KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK--PAPKELAPTTTKGPTSTTSDKPAP 820

Query: 1311 TPPAATPPS-PKGSPGTPPPKGAPTPPAVTPP--SPKGTPTLPA--TTPSSKGGPTTPSS 1365
            T P  T P+ PK    T P K APT P   PP  S   TPT     TT       +TP  
Sbjct: 821  TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 880

Query: 1366 KEGPTPPAA--TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATP-VTR 1422
               PTP A   +P   G P    P+  + P + +   D T+   +  +P+   A P +T+
Sbjct: 881  SAEPTPKALENSPKEPGVPTTKTPAATK-PEMTTTAKDKTTERDLRTTPETTTAAPKMTK 939

Query: 1423 EGAATPSKG------------------DLTPPAVTPV----------SLKKAPATSAPKG 1454
            E A T  K                   D TP  +T +          + KK   T+    
Sbjct: 940  ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMN 999

Query: 1455 GPA-TPSSKGDPTLPAVTPPSPKEPP-APKQVATSSSPKKAPATPAPMGAPTLPAVIPSS 1512
             P  T   K   T    T P P++P  APK+  ++  PK  P    P   PT        
Sbjct: 1000 KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPT-------- 1051

Query: 1513 PKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPA 1572
                P   +S    + PT+ +       T  P +                  P  K    
Sbjct: 1052 ----PRKMTSTMPELNPTSRIAEAMLQTTTRPNQT-----------------PNSKLVEV 1090

Query: 1573 TPSSKEASSPPAVTP 1587
             P S++A      TP
Sbjct: 1091 NPKSEDAGGAEGETP 1105



 Score =  259 bits (661), Expect = 2e-68
 Identities = 305/1086 (28%), Positives = 403/1086 (37%), Gaps = 143/1086 (13%)

Query: 477  PTSPAALVMAPVAPKEPSTQVATTLRIPVSP------PLPDPEDL--------KNLPSSV 522
            PTSP +   AP       T  +TT R P  P       + + E++            SS 
Sbjct: 110  PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 169

Query: 523  LVKFPTQKDLQTVPASLEGAPFSPAQAGL--------TTKKDPTVLPLV---QAAPKNSP 571
                 +   ++ + +S   A     Q  L         TKK PT  P V     +  ++ 
Sbjct: 170  SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNG 229

Query: 572  SFQ------STSSSPEIPLSPEATLAKKSLGEP-LPIGKPASSMTSPLGVNSSASV---- 620
             F+      ST+   ++  SP+ T AK     P LP     S  TS L VN   +V    
Sbjct: 230  DFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETS-LTVNKETTVETKE 288

Query: 621  ----IKTDSYAGPDSAGPLLKSSLITPT----VAAFPLESADPAGVAPTTAKGTSTYTTT 672
                 K  S  G +      ++  I  T    +A      A P   A TT KG +  TT 
Sbjct: 289  TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA-LTTP 347

Query: 673  ASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNT-CAPLATLVLAPEIP 731
              P    T    P +   KE T TT+   PT     P  P+P  T  AP      AP   
Sbjct: 348  KEP--TPTTPKEPASTTPKEPTPTTIKSAPTT----PKEPAPTTTKSAPTTPKEPAPTTT 401

Query: 732  KSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLA 791
            K  P+P+ P    P  TK+           P  ++ K  PT     + T   K       
Sbjct: 402  KE-PAPTTPKEPAPTTTKE-----------PAPTTTKSAPTTPKEPAPTTPKK------- 442

Query: 792  DSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPA 851
              P+P     +P+   P T K    P TP     +P +   A   P+        K +P 
Sbjct: 443  --PAP----TTPKEPAPTTPK-EPTPTTP--KEPAPTTKEPAPTTPKEPAPTAPKKPAPT 493

Query: 852  TTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPAL 911
            T   P P +PK  P P+     SP      PKE    +  + P   + PA    K AP  
Sbjct: 494  TPKEPAPTTPK-EPAPTTTKEPSP----TTPKEPAPTTTKSAPTTTKEPAPTTTKSAP-- 546

Query: 912  SMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK----GGPATPSPKWAPTPPA 967
                ++PK+   T   +  P +P      TP    P +PK      P  P+P     P  
Sbjct: 547  ----TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 602

Query: 968  ATPPSPKGGPATPSPKGAPTPPAATPPSP-KGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026
             TP  P   P TP      TP   TP +P K  P TP      TP  + P +P+     T
Sbjct: 603  TTPKEP--APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 660

Query: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT 1086
            P     +TP AA P +PK  PA T   + APTTP       +  P TP  + APT P  T
Sbjct: 661  PEEPAPTTPKAAAPNTPK-EPAPTTPKEPAPTTP------KEPAPTTPK-ETAPTTPKGT 712

Query: 1087 PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAAT-PPSPKGGLATPPP 1145
             P+    PA  +PK  P P    P + K   +T   K APTTP  T P +PK    T P 
Sbjct: 713  APTTLKEPAPTTPK-KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 771

Query: 1146 KGAPTTPAATPPSP-KGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT-PP 1203
            + APTTP  T P+  K    T P K AP   A  P + KG  +T S K APTTP  T P 
Sbjct: 772  EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA--PTTTKGPTSTTSDKPAPTTPKETAPT 829

Query: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP----------PSPKG 1253
            +PK    T   K APTTP  TPP     ++TP+    PTT   +P          P+PK 
Sbjct: 830  TPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 888

Query: 1254 GPATPPPKGAPT--PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP------ATSP 1305
               +P   G PT   PAAT P +     T   K        TP +    P      AT+ 
Sbjct: 889  LENSPKEPGVPTTKTPAATKPEM---TTTAKDKTTERDLRTTPETTTAAPKMTKETATTT 945

Query: 1306 PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLP--ATTPSSKGGPTTP 1363
             K   +   AT      +          T    T  +PK T T     TT        T 
Sbjct: 946  EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA 1005

Query: 1364 SSKEGPTPPAATPSHKGGPAMTP------PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA 1417
              K+  T   AT      P   P        PK  P +  PK  PT   +    P+  P 
Sbjct: 1006 KPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 1065

Query: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477
            + +      T ++ + TP +       K+      +G       +    +P VTP     
Sbjct: 1066 SRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYL 1125

Query: 1478 PPAPKQ 1483
            P  P Q
Sbjct: 1126 PRVPNQ 1131



 Score =  239 bits (610), Expect = 2e-62
 Identities = 322/1179 (27%), Positives = 428/1179 (36%), Gaps = 216/1179 (18%)

Query: 257  SPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSS 316
            +P +P S S K P  PP+  S + +S    T+ +    PN      +     +   H  S
Sbjct: 109  NPTSPPS-SKKAP--PPSGASQTIKS----TTKRSPKPPNKKKTKKVIESEEITEEH--S 159

Query: 317  FGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPV 376
                Q    +  S+ S  T++ I    +S      + R +   L  ++     T      
Sbjct: 160  VSENQESSSSSSSSSSSSTIRKIKSSKNSA-----ANRELQKKLKVKDNKKNRTKKKPTP 214

Query: 377  VAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQ--MPVS 434
              P VD+  S + +      G   V T    S T    + +SP  T   P+  +  +P +
Sbjct: 215  KPPVVDEAGSGLDN------GDFKVTTP-DTSTTQHNKVSTSPKITTAKPINPRPSLPPN 267

Query: 435  SVGT--TPLVVTNPCTIAAAPTTTFEVATCVS---PPMSSGPISNIEPTS-----PAALV 484
            S  +  T L V    T+    TTT    T         S+    +IE TS     P + V
Sbjct: 268  SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 327

Query: 485  MAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPF 544
            +A   PK  +T     L  P  P    P++    P+S   K PT       P +++ AP 
Sbjct: 328  LAKPTPKAETTTKGPALTTPKEPTPTTPKE----PASTTPKEPT-------PTTIKSAPT 376

Query: 545  SPAQ-AGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGK 603
            +P + A  TTK  PT        PK      +   +P  P  P  T  K+          
Sbjct: 377  TPKEPAPTTTKSAPTT-------PKEPAPTTTKEPAPTTPKEPAPTTTKE---------- 419

Query: 604  PASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTA 663
            PA + T                           KS+  TP   A       P   APTT 
Sbjct: 420  PAPTTT---------------------------KSAPTTPKEPA----PTTPKKPAPTTP 448

Query: 664  KGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLAT 723
            K  +  TT   P             P +    T  P   T  E  P AP           
Sbjct: 449  KEPAP-TTPKEP---------TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP-------- 490

Query: 724  LVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASS 783
               AP  PK  P+P+ P    P  TK+    S T+   P  ++ K  PT     + T + 
Sbjct: 491  ---APTTPKE-PAPTTPKEPAPTTTKEP---SPTTPKEPAPTTTKSAPTTTKEPAPTTTK 543

Query: 784  KGTLTYLADSPSPLGVSVSPQTKRP-PTKKGSAGPDTPIGNLSSPVSPVE-ASFLPENSL 841
                T    SP+         TK P PT      P TP     +P +P E A   P+   
Sbjct: 544  SAPTTPKEPSPT--------TTKEPAPTTPKEPAPTTP--KKPAPTTPKEPAPTTPK--- 590

Query: 842  SFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPA 901
                 + +P TT  P P +PK  P P+     +P   T P K TPT         K  P 
Sbjct: 591  -----EPAPTTTKKPAPTTPK-EPAPTTPKETAP---TTPKKLTPTTP------EKLAPT 635

Query: 902  TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKW 961
            TP  K AP      ++P++   T   +  P +P      TP AA P +PK     P+P  
Sbjct: 636  TP-EKPAP------TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK----EPAPTT 684

Query: 962  APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG 1021
               P   TP  P   P TP  + APT P  T P+    PA  +PK  P P  + P + K 
Sbjct: 685  PKEPAPTTPKEP--APTTPK-ETAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTTK- 739

Query: 1022 SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPT 1081
             P +T   K A T P  T P+    PA T   + APTTP  T P+    PA P+    P 
Sbjct: 740  EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA-PTTPKKPA 798

Query: 1082 PPAATPPSPKGGPATPSPKGAPMPPAAT-PPSPKGGLATPPHKGAPTTPAATPPSPKGGL 1140
            P    P + KG  +T S K AP  P  T P +PK    T P K APTTP  TPP     +
Sbjct: 799  PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEV 857

Query: 1141 ATPPPKGAPTTPAATP----------PSPKGGLATPPPKGAPT--TPAATPPSPKGGLAT 1188
            +TP     PTT   +P          P+PK    +P   G PT  TPAAT P       T
Sbjct: 858  STPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM---TTT 914

Query: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248
               K        TP +      T +PK    T   T  + +  +   + +   TT   T 
Sbjct: 915  AKDKTTERDLRTTPET-----TTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 969

Query: 1249 P--SPKGGPATPPPKGAPTPPAATPPSL--KGGLATPPHKGAPNPAVVTPPSPKGGPATS 1304
            P         T  PK   T    T   +  K      P   A N    TP   K      
Sbjct: 970  PFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK------ 1023

Query: 1305 PPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP------------TLPAT 1352
             P  AP  P +T   PK  P    PK  PTP  +T   P+  P            T P  
Sbjct: 1024 -PTKAPKKPTST-KKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQ 1081

Query: 1353 TPSSKGGPTTPSSK-----EGPTPPAATPSHKGGPAMTP 1386
            TP+SK     P S+     EG TP      H   P +TP
Sbjct: 1082 TPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTP 1120



 Score =  225 bits (574), Expect = 3e-58
 Identities = 265/973 (27%), Positives = 363/973 (37%), Gaps = 152/973 (15%)

Query: 981  SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP 1040
            +P   P+   A PPS        + K +P PP                    S    ++ 
Sbjct: 109  NPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS 168

Query: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100
             S   S ++T     +    AA     K       LK        T   P   P      
Sbjct: 169  SSSSSSSSSTIRKIKSSKNSAANRELQK------KLKVKDNKKNRTKKKPTPKPPVVDEA 222

Query: 1101 GAPMP----PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156
            G+ +        TP +     +T  H    T+P  T   P     + PP    +   +  
Sbjct: 223  GSGLDNGDFKVTTPDT-----STTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLT 277

Query: 1157 PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1216
             + +  + T       TT      S  G   T S K   +              T +   
Sbjct: 278  VNKETTVETKE-----TTTTNKQTSTDGKEKTTSAKETQSIEK-----------TSAKDL 321

Query: 1217 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG 1276
            APT+     P+PK    T  P         TP  P   P TP    + TP   TP ++K 
Sbjct: 322  APTSKVLAKPTPKAETTTKGPA------LTTPKEPT--PTTPKEPASTTPKEPTPTTIKS 373

Query: 1277 GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP 1336
               T P + AP      P +PK    T+  + APT P    P+    P     K APT P
Sbjct: 374  A-PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 432

Query: 1337 AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP 1396
                P+   TP  PA T   +  PTTP      TP    P+ K     TP  P   P  P
Sbjct: 433  KEPAPT---TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP--APTAP 487

Query: 1397 SPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGP 1456
                  T     P +PK+ PA   T+E + T      TP    P + K AP T+     P
Sbjct: 488  KKPAPTTPKEPAPTTPKE-PAPTTTKEPSPT------TPKEPAPTTTKSAPTTTKE---P 537

Query: 1457 ATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEV 1516
            A  ++K  PT P    P+  + PAP            P  PAP   P  PA  P++PKE 
Sbjct: 538  APTTTKSAPTTPKEPSPTTTKEPAPT----------TPKEPAPT-TPKKPA--PTTPKE- 583

Query: 1517 PATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE-APATPS 1575
            PA P++ ++P APT T    K PA   PKE               PA  TPKE AP TP 
Sbjct: 584  PA-PTTPKEP-APTTT----KKPAPTTPKE---------------PAPTTPKETAPTTPK 622

Query: 1576 SKEASSPPAVTPST-YKGAPSPKELLIPPAVTSPSP----KEAPTPPAVTPPSPEKGPAT 1630
                ++P  + P+T  K AP+  E L P     P+P    + APT P    P+  K PA 
Sbjct: 623  KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 682

Query: 1631 PAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAP 1690
              PK    + P  P+     PT+P         T P   KG      PT LKE    PAP
Sbjct: 683  TTPKEPAPTTPKEPA-----PTTPKE-------TAPTTPKGT----APTTLKE----PAP 722

Query: 1691 ESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQ------KD 1744
             +TP   AP    P T K   ++    P P+   G+  P +   PAP  P +      K 
Sbjct: 723  -TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT-APTTPKEPAPTTPKEPAPTTPKG 780

Query: 1745 SSKTAKGKDASHSPKGP----LAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSL 1800
            ++ T   + A  +PK P    LAP  +K  T  T+       PK  + +    P+P  + 
Sbjct: 781  TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP--TT 838

Query: 1801 PLAPSP-VPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVL 1859
            P  P+P  P  PP      S+P    E  +   +P   DE  P +  EP          L
Sbjct: 839  PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP---DESTPELSAEPT------PKAL 889

Query: 1860 VNMPTPKSAGIP-VPTPSAKQP-VTKNNKGSGTESD------SDESVPEL--EEQDSTQA 1909
             N  +PK  G+P   TP+A +P +T   K   TE D      +  + P++  E   +T+ 
Sbjct: 890  EN--SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 947

Query: 1910 TTQQAQLAAAAEI 1922
            TT+    A   ++
Sbjct: 948  TTESKITATTTQV 960



 Score =  209 bits (532), Expect = 2e-53
 Identities = 271/949 (28%), Positives = 353/949 (37%), Gaps = 140/949 (14%)

Query: 1080 PTPPAATPPSPKGGPATPSPKGAPMPP--AATPPSPKGGLATPPHKGAPTTPAATPPSPK 1137
            P+   A PPS        + K +P PP    T    +    T  H  +    +++  S  
Sbjct: 114  PSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSS 173

Query: 1138 GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP----------KGGLA 1187
               +T     +    AA     K  L     K   T    TP  P           G   
Sbjct: 174  SSSSTIRKIKSSKNSAANRELQKK-LKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFK 232

Query: 1188 TPSPKGAPTTPAATPPSPKGGLATP-SPKGAPTTPAATPPSPKGGLA-----TPSPKGAP 1241
              +P  + T       SPK   A P +P+  P+ P  +  S +  L      T   K   
Sbjct: 233  VTTPDTSTTQHNKVSTSPKITTAKPINPR--PSLPPNSDTSKETSLTVNKETTVETKETT 290

Query: 1242 TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP 1301
            TT   T  S  G   T   K   +    +   L           AP   V+  P+PK   
Sbjct: 291  TTNKQT--STDGKEKTTSAKETQSIEKTSAKDL-----------APTSKVLAKPTPKAET 337

Query: 1302 ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361
             T  P    TP   TP +PK    T P +  PT     P +PK     PA T ++K  PT
Sbjct: 338  TTKGP-ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKE----PAPT-TTKSAPT 391

Query: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV-IPLSPKK-APATP 1419
            TP      T     P+    PA   P+  + PA  + K  PT+P    P +PKK AP TP
Sbjct: 392  TPKEPAPTTTKEPAPTTPKEPA---PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 448

Query: 1420 VTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV-TPPSPKEP 1478
              +E A T  K         P    K PA + PK    T   K  PT P    P +PKEP
Sbjct: 449  --KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 506

Query: 1479 PAPKQVATSSSPKKAPATPAPMGAPTL---PAVIPSSPKEVPATPSSRRDPIAPTATLLS 1535
                    S +  K PA      APT    PA  P++ K  P TP   ++P +PT T   
Sbjct: 507  APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA--PTTTKSAPTTP---KEP-SPTTT--- 557

Query: 1536 KKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE-APATPSSKEASSPPAVTPSTYKGAP 1594
             K PA   PKE    PA T P   K PA  TPKE AP TP        PA T +      
Sbjct: 558  -KEPAPTTPKE----PAPTTP---KKPAPTTPKEPAPTTPKE------PAPTTTKKPAPT 603

Query: 1595 SPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP----PVTPSS-LKD 1649
            +PKE    PA T+P      TP  +TP +PEK   T   K  PT+P    P TP      
Sbjct: 604  TPKE----PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 659

Query: 1650 SPTSPASVTCKMGA--TVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTR-KG--P 1704
            +P  PA  T K  A  T  + +   P +  PT  KE    PAP +TP  TAPT  KG  P
Sbjct: 660  TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE----PAP-TTPKETAPTTPKGTAP 714

Query: 1705 QTKKSSATSPPICPDPS--AKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPL 1762
             T K  A + P  P P   A   +K P ST    P     K ++ T   + A  +PK P 
Sbjct: 715  TTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP- 773

Query: 1763 APPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPV--PTLPPKQQFLPSS 1820
            AP   K + P T        P P +      P  P    LAP+    PT     +  P++
Sbjct: 774  APTTPKGTAPTTLKE-----PAPTT------PKKPAPKELAPTTTKGPTSTTSDKPAPTT 822

Query: 1821 PGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQP 1880
            P        K  AP    E  P  P +P              P P ++ +  PT + K+P
Sbjct: 823  P--------KETAPTTPKEPAPTTPKKPAP-------TTPETPPPTTSEVSTPT-TTKEP 866

Query: 1881 VTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQ------LAAAAEIDEEPVSKAKQSR 1934
             T            DES PEL  + + +A     +          A    E  + AK   
Sbjct: 867  TT-------IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 919

Query: 1935 SEKKARKA-MSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDT 1982
            +E+  R    +     ++T  T  T  K+       T   V  +   DT
Sbjct: 920  TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDT 968



 Score =  166 bits (420), Expect = 2e-40
 Identities = 268/1120 (23%), Positives = 382/1120 (34%), Gaps = 174/1120 (15%)

Query: 154  PPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVP 213
            PP+   +PP    +++    T  +P  P++ KT    + SE +                 
Sbjct: 113  PPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTK-KVIESEEITEE-------------- 157

Query: 214  YHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPP 273
             H V+      S  +S   ++    +  +     +  +   L    N  + + K P   P
Sbjct: 158  -HSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKP 216

Query: 274  AALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSD 333
              +  +   L       K   P+T                                  S 
Sbjct: 217  PVVDEAGSGLD--NGDFKVTTPDT----------------------------------ST 240

Query: 334  PTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVV----APSVDKGPST-- 387
                 +S     T A   + R  +PP    ++    TV     V      + +K  ST  
Sbjct: 241  TQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDG 300

Query: 388  -ISSITCSPSGSLNVATSFSLSPTTSLILKSSPNA--TYHYPLVA-------QMPVSSVG 437
               + +   + S+   ++  L+PT+ ++ K +P A  T   P +          P     
Sbjct: 301  KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAS 360

Query: 438  TTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQV 497
            TTP   T P TI +APTT  E A   +    S P +  EP        AP  PKEP+   
Sbjct: 361  TTPKEPT-PTTIKSAPTTPKEPAPTTT---KSAPTTPKEPAPTTTKEPAPTTPKEPA--- 413

Query: 498  ATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDP 557
                  P +   P P   K+ P++     PT           + AP +P +   TT K+P
Sbjct: 414  ------PTTTKEPAPTTTKSAPTTPKEPAPT--------TPKKPAPTTPKEPAPTTPKEP 459

Query: 558  TVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSS 617
            T        PK  P+  +   +P  P  P  T  KK    P P      + T+P     +
Sbjct: 460  T-----PTTPK-EPAPTTKEPAPTTPKEPAPTAPKK----PAPTTPKEPAPTTP--KEPA 507

Query: 618  ASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFL 677
             +  K  S   P    P    S   PT    P         APTT K   T     SP  
Sbjct: 508  PTTTKEPSPTTPKEPAPTTTKS--APTTTKEP---------APTTTKSAPTTPKEPSP-- 554

Query: 678  EGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSP 737
              T +  P     KE   TT P  P  +     AP+     AP  T   AP  PK  P+P
Sbjct: 555  --TTTKEPAPTTPKEPAPTT-PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-PAP 610

Query: 738  SLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPL 797
            + P    P   KK+   +    LAP  +  K  PT     + T   + T T   + P+P 
Sbjct: 611  TTPKETAPTTPKKLTPTT-PEKLAP-TTPEKPAPTTPEELAPTTPEEPTPT-TPEEPAP- 666

Query: 798  GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVE-ASFLPENSLSFQGSKDSPATTHSP 856
                +P+   P T K  A P TP     +P +P E A   P+ +        +P T   P
Sbjct: 667  ---TTPKAAAPNTPKEPA-PTTP--KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 720

Query: 857  TPPSPKG------APT----PSAVT-----PLSPKGVTLPPKETPTPSVVNLPFPKEGPA 901
             P +PK       APT    P++ T     P +PKG      + P P+    P P     
Sbjct: 721  APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 780

Query: 902  T-PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK 960
            T P   + PA +       K  A    KG  ++ S K APT P  T P+    PA  +PK
Sbjct: 781  TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK 840

Query: 961  W-APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAV-TPPS 1018
              APT P  TPP      +TP+    PT    +P       +TP     PTP A+   P 
Sbjct: 841  KPAPTTP-ETPPPTTSEVSTPTTTKEPTTIHKSPDE-----STPELSAEPTPKALENSPK 894

Query: 1019 PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG 1078
              G P         +  PAAT P    +       +   TTP  T  +PK    T +   
Sbjct: 895  EPGVP--------TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTE 946

Query: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138
              T    T  + +   +T +    P        +      T   K   TT     P    
Sbjct: 947  KTTESKITATTTQ-VTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPE--- 1002

Query: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198
               T  PK   T   AT P P+       P  AP  P +T   PK       PK  PT  
Sbjct: 1003 --ETAKPKDRATNSKATTPKPQ------KPTKAPKKPTST-KKPKTMPRVRKPKTTPTPR 1053

Query: 1199 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1238
              T   P+    +   +    T      +P   L   +PK
Sbjct: 1054 KMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPK 1093



 Score =  144 bits (363), Expect = 9e-34
 Identities = 172/675 (25%), Positives = 236/675 (34%), Gaps = 91/675 (13%)

Query: 1317 PPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATP 1376
            P SP  S   PPP GA             + T+ +TT  S   P    +K+       T 
Sbjct: 110  PTSPPSSKKAPPPSGA-------------SQTIKSTTKRSPKPPNKKKTKKVIESEEITE 156

Query: 1377 SHKGGP----AMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK--------------KAPAT 1418
             H        + +  S      I   K    S A   L  K                P  
Sbjct: 157  EHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKP 216

Query: 1419 PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP 1478
            PV  E  +    GD         + +    +++PK   A P +      P++ P S    
Sbjct: 217  PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR----PSLPPNSDTSK 272

Query: 1479 PAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKT 1538
                 V   ++ +    T       T      +S KE  +   +    +APT+ +L+K T
Sbjct: 273  ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT 332

Query: 1539 PA--TLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAP-S 1595
            P   T     AL  P    P+  K PA  TPKE   T      ++P    P+T K AP +
Sbjct: 333  PKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 392

Query: 1596 PKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP----PVTPSS-LKDS 1650
            PKE   P   T+  P  APT P    P+  K PA    K  PT+P    P TP      +
Sbjct: 393  PKE---PAPTTTKEP--APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 447

Query: 1651 PTSPASVTCKMGA-TVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKS 1709
            P  PA  T K    T P+       +  PT  KE   AP     P  T P    P T K 
Sbjct: 448  PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE--PAPTAPKKPAPTTPKEPAPTTPKE 505

Query: 1710 SA------TSPPICPDPSAKNGSKGPLSTVAPAPLL-----PVQKDSSKTAKGKDASHSP 1758
             A       SP    +P+       P +T  PAP          K+ S T   + A  +P
Sbjct: 506  PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 565

Query: 1759 KGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSP------VPTLPP 1812
            K P AP   K   P T        PK  + + +  P+P  + P  P+P       PT P 
Sbjct: 566  KEP-APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP--TTPKEPAPTTPKETAPTTPK 622

Query: 1813 KQQFLPSSP-GLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIP 1871
            K    P++P  L   +P KP AP   +EL P  P E               PTP +   P
Sbjct: 623  K--LTPTTPEKLAPTTPEKP-APTTPEELAPTTPEE---------------PTPTTPEEP 664

Query: 1872 VP-TPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKA 1930
             P TP A  P T       T  +   + P+     + + T        A    +EP    
Sbjct: 665  APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 724

Query: 1931 KQSRSEKKARKAMSK 1945
             +  + K+     +K
Sbjct: 725  PKKPAPKELAPTTTK 739



 Score =  135 bits (341), Expect = 3e-31
 Identities = 228/952 (23%), Positives = 330/952 (34%), Gaps = 158/952 (16%)

Query: 66   PFPSP-------STIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAA--- 115
            P P P       S + +   +V  P +S+     + T+P+  T  P    P + P +   
Sbjct: 212  PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 271

Query: 116  ----------LALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFP----PNLLTSP 161
                        + +     T K T +        A    S++K+SA        +L  P
Sbjct: 272  KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 331

Query: 162  -PSVAVAESGSVITLS---APIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCV 217
             P       G  +T      P  P EP +   K P+            P  + + P    
Sbjct: 332  TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT------------PTTIKSAP---T 376

Query: 218  TPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALS 277
            TP     +   S P TTP       + +   TT       P+ P   + K P       +
Sbjct: 377  TPKEPAPTTTKSAP-TTPKEPAPTTTKEPAPTT-------PKEPAPTTTKEPAPTTTKSA 428

Query: 278  LSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVK 337
             +T   P  T+ +K A P TP                          +  P+   +PT  
Sbjct: 429  PTTPKEPAPTTPKKPA-PTTPK-------------------------EPAPTTPKEPTPT 462

Query: 338  TISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSG 397
            T      +T    P+  +   P P+  +    T    P  AP+  K P+  ++   SP+ 
Sbjct: 463  TPKEPAPTT--KEPAPTTPKEPAPTAPKKPAPTTPKEP--APTTPKEPAPTTTKEPSPT- 517

Query: 398  SLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTF 457
                 T    +PTT+   KS+P  T      A     S  TTP   +   T   APTT  
Sbjct: 518  -----TPKEPAPTTT---KSAPTTTKE---PAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 566

Query: 458  EVATCV------SPPMSSGPISNIEPTSPAALVMAPVAPKEPS----TQVATTLRIPVSP 507
            E A         + P    P +  EP        AP  PKEP+     + A T    ++P
Sbjct: 567  EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 626

Query: 508  PLPD------PEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLP 561
              P+      PE  K  P++     PT  +  T     E AP +P  A   T K+P    
Sbjct: 627  TTPEKLAPTTPE--KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTT 684

Query: 562  LVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPI--GKPASSMTSPLGVNSSAS 619
              + AP        T+     P +P+ T A  +L EP P    KPA    +P       +
Sbjct: 685  PKEPAPTTPKEPAPTTPKETAPTTPKGT-APTTLKEPAPTTPKKPAPKELAP-------T 736

Query: 620  VIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEG 679
              K  +    D   P        PT    P  +  P   APTT KGT+  T      L+ 
Sbjct: 737  TTKEPTSTTCDKPAPTTPKG-TAPTTPKEPAPTT-PKEPAPTTPKGTAPTT------LKE 788

Query: 680  TVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSL 739
                 PK    KE   TT    PT++ +   AP+     AP      AP  PK  P+P+ 
Sbjct: 789  PAPTTPKKPAPKELAPTTTK-GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK-PAPTT 846

Query: 740  PPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGV 799
            P    PP T +V   + T     +  SP E   E        S++ T   L +SP   GV
Sbjct: 847  PET-PPPTTSEVSTPTTTKEPTTIHKSPDESTPE-------LSAEPTPKALENSPKEPGV 898

Query: 800  SVSPQTKRPPTKKGSAGP------------DTPIGNLSSPVSPVEASFLPENSLSFQGSK 847
               P TK P   K                  TP    ++P    E +   E +   + + 
Sbjct: 899  ---PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITA 955

Query: 848  DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP---ATPA 904
             +   T + T  +     T    T L+PK VT   K   T  ++N P     P   AT +
Sbjct: 956  TTTQVTSTTTQDTTPFKITTLKTTTLAPK-VTTTKKTITTTEIMNKPEETAKPKDRATNS 1014

Query: 905  PKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT 956
                P     + +PKK  +T  PK +P    PK  PTP   T   P+  P +
Sbjct: 1015 KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTS 1066



 Score =  119 bits (299), Expect = 2e-26
 Identities = 189/790 (23%), Positives = 276/790 (34%), Gaps = 98/790 (12%)

Query: 6    TETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQAS 65
            T+++  T  +   P ++    P   A + T      GP L  P  P P   P   A+   
Sbjct: 310  TQSIEKTSAKDLAPTSKVLAKPTPKAETTTK-----GPALTTPKEPTPTT-PKEPASTTP 363

Query: 66   PFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTF----LPNLIGPPISPAALALASP 121
              P+P+TI S P     P  ++  + P      APT      P     P +P      +P
Sbjct: 364  KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP-APTTTKEPAP 422

Query: 122  MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAP 181
                +   TP   AP      AP + ++ +   P     P      E        AP  P
Sbjct: 423  TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK---EPTPTTPKEPAPTTKEPAPTTP 479

Query: 182  SEPKTNLNKVPSEVVPNPKG--TPSPPCIVSTVPYHCVTPMASIQSGVASLPQTT----P 235
             EP     K P+   P      TP  P   +T      TP     +   S P TT    P
Sbjct: 480  KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 539

Query: 236  TTTLAIASPQVK---DTTISSVLISPQNPGSLSLKGPV-SPPAALSLSTQSLPVVTSSQK 291
            TTT +  +   +    TT      +P+ P   + K P  + P   + +T   P  T+++K
Sbjct: 540  TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 599

Query: 292  TAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPT----VKTISVDHSSTG 347
             A P TP +   +     AP       + + L  T P  L+  T      T   + + T 
Sbjct: 600  PA-PTTPKEPAPTTPKETAPT------TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 652

Query: 348  ASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSL 407
               P+  +   P P+  +         P  AP+  K P+  +    +P+      T    
Sbjct: 653  PEEPTPTTPEEPAPTTPKAAAPNTPKEP--APTTPKEPAPTTPKEPAPT------TPKET 704

Query: 408  SPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFE--VATCVSP 465
            +PTT       P  T    L    P     TTP     P     APTTT E    TC  P
Sbjct: 705  APTT-------PKGTAPTTLKEPAP-----TTP---KKPAPKELAPTTTKEPTSTTCDKP 749

Query: 466  -PMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLR--IPVSPPLPDPEDLKNLPSSV 522
             P +    +   P  PA       AP  P     TTL+   P +P  P P++L    +  
Sbjct: 750  APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 809

Query: 523  LVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQST------ 576
                 + K   T P   E AP +P +   TT K P   P     P  + S  ST      
Sbjct: 810  PTSTTSDKPAPTTPK--ETAPTTPKEPAPTTPKKPA--PTTPETPPPTTSEVSTPTTTKE 865

Query: 577  ---------SSSPEIPLSPEATLAKKSLGEP-LPIGKPASSMTSPLGVNSSASVIKTDSY 626
                      S+PE+   P     + S  EP +P  K  ++    +   +     + D  
Sbjct: 866  PTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLR 925

Query: 627  AGPD--SAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPF---LEGTV 681
              P+  +A P +     T T      E    + +  TT + TST T   +PF      T 
Sbjct: 926  TTPETTTAAPKMTKETATTT------EKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 979

Query: 682  SLAPKNHPVKEGTLTTLPLVPTASENCPV---APSPQNTCAPLATLVLAPEIPKSVPSPS 738
            +LAPK    K+ T+TT  ++    E       A + + T         AP+ P S   P 
Sbjct: 980  TLAPKVTTTKK-TITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPK 1038

Query: 739  LPPAGTPPGT 748
              P    P T
Sbjct: 1039 TMPRVRKPKT 1048



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 70/280 (25%), Positives = 99/280 (35%), Gaps = 25/280 (8%)

Query: 2   PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
           P    E  P T +E P P       P +   +      +P PT P   +P   + P    
Sbjct: 642 PTTPEELAPTTPEE-PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 700

Query: 62  NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAP---EAPTFLPNLIGPPISPAALAL 118
            + +   +P   A T L+ P P +    A P   AP   + PT        P +P   A 
Sbjct: 701 PKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759

Query: 119 ASPMI-APTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSA 177
            +P   APT   TP   AP      AP ++++ +   P              G   T S 
Sbjct: 760 TTPKEPAPT---TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 816

Query: 178 PIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTT 237
             AP+ PK      P E  P     P+P     T P    TP  +  +   S P TT   
Sbjct: 817 KPAPTTPKETAPTTPKEPAPTTPKKPAP-----TTP---ETPPPT--TSEVSTPTTTKEP 866

Query: 238 TLAIASPQVK------DTTISSVLISPQNPGSLSLKGPVS 271
           T    SP         + T  ++  SP+ PG  + K P +
Sbjct: 867 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 906


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score =  300 bits (767), Expect = 1e-80
 Identities = 288/904 (31%), Positives = 378/904 (41%), Gaps = 109/904 (12%)

Query: 848  DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907
            D+  T H+    SPK     +   P++P+  +LPP  + T    +L   KE   T   K+
Sbjct: 103  DTSTTQHNKVSTSPK----ITTAKPINPRP-SLPPN-SDTSKETSLTVNKE--TTVETKE 154

Query: 908  APALSMTSSSPKKARATPAPK--GIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965
                +  +S+  K + T A +   I  + +   APT      P+PK    T  P    TP
Sbjct: 155  TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT-TP 213

Query: 966  PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAA 1025
               TP +PK   +T       TP   TP + K  P TP  + APT     P +PK  PA 
Sbjct: 214  KEPTPTTPKEPAST-------TPKEPTPTTIKSAPTTPK-EPAPTTTKSAPTTPK-EPAP 264

Query: 1026 TPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS--PKGGPATPSLKGAPTPP 1083
            T   + A T P    P+    PA T   K APTTP    P+   K  P TP      TP 
Sbjct: 265  TTTKEPAPTTPKEPAPTTTKEPAPT-TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 323

Query: 1084 AATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP-AATPPSPKGGLAT 1142
              TP +PK        + AP      P +PK    T P K APTTP    P +PK    T
Sbjct: 324  EPTPTTPK--------EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 375

Query: 1143 PPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1202
               + +PTTP    P+      T   + APTT  + P +PK    T + + APTTP    
Sbjct: 376  TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 435

Query: 1203 PSPKGGLATPSPKGAPTTP-AATPPSPKGGLATPSPKGAPTTP-AATPPSPKGGPATPPP 1260
            P       T   K APTTP    P +PK    T + K APTTP    P +PK    T P 
Sbjct: 436  P-------TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 488

Query: 1261 KGAPTPPAATPPSLKGGLATPPHKGAP-NPAVVTPPSPKGGPATSPPKGAP-TPPAATPP 1318
            K  PT P    P       T P K AP  P  + P +P+    T+P + AP TP AA P 
Sbjct: 489  KLTPTTPEKLAP-------TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN 541

Query: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378
            +PK    T P + APT    TP  P   PT P  T  +    T P++ + P P   TP  
Sbjct: 542  TPKEPAPTTPKEPAPT----TPKEP--APTTPKETAPTTPKGTAPTTLKEPAP--TTPKK 593

Query: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSP-AVIPLSPKK-APATPVTREGAATPSKG----D 1432
                 + P + K   +    K  PT+P    P +PK+ AP TP  +E A T  KG     
Sbjct: 594  PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTP--KEPAPTTPKGTAPTT 651

Query: 1433 LTPPAVTPVSLKKAPATSAP---KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSS 1489
            L  PA T    K AP   AP   KG  +T S K  PT P  T P+  + PAP      ++
Sbjct: 652  LKEPAPT-TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP------TT 704

Query: 1490 PKK-APATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL--APKE 1546
            PKK AP TP      T     P++ KE P T    + P   T  L ++ TP  L  +PKE
Sbjct: 705  PKKPAPTTPETPPPTTSEVSTPTTTKE-PTT--IHKSPDESTPELSAEPTPKALENSPKE 761

Query: 1547 ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPS-PKELLIPPAV 1605
              +P         KTPA   P E   T   K        TP T   AP   KE       
Sbjct: 762  PGVPTT-------KTPAATKP-EMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 813

Query: 1606 TSPSPKEAPTPPAVTPPSPEKGP--------ATPAPKGTPTSPPVTPSSLKDSP---TSP 1654
            T+ S   A T    +  + +  P         T APK T T   +T + + + P     P
Sbjct: 814  TTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKP 873

Query: 1655 ASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSP 1714
                    AT P+  K   A K PT+ K+      P++ P +  P +  P  +K ++T P
Sbjct: 874  KDRATNSKATTPKPQKPTKAPKKPTSTKK------PKTMPRVRKP-KTTPTPRKMTSTMP 926

Query: 1715 PICP 1718
             + P
Sbjct: 927  ELNP 930



 Score =  285 bits (728), Expect = 4e-76
 Identities = 278/915 (30%), Positives = 356/915 (38%), Gaps = 131/915 (14%)

Query: 735  PSPSLPP-AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADS 793
            P PSLPP + T   T        T       ++ K+  T+  G   T S+K T +    S
Sbjct: 126  PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTD--GKEKTTSAKETQSIEKTS 183

Query: 794  PSPLG----VSVSPQTKRPPTKKGSA--GPDTPIGNLSSPVSPVEASFLPENSLSFQGSK 847
               L     V   P  K   T KG A   P  P     +P +P E +       +    K
Sbjct: 184  AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP-----TPTTPKEPASTTPKEPTPTTIK 238

Query: 848  DSPATTHSPTPPSPKGAPT----PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903
             +P T   P P + K APT    P+  T   P   T  PKE P P+    P P    + P
Sbjct: 239  SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT--PKE-PAPTTTKEPAPTTTKSAP 295

Query: 904  APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963
               + PA     ++PKK   T   +  P +P      TP    P + +  P TP    AP
Sbjct: 296  TTPKEPA----PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP-AP 350

Query: 964  TPPAATPPSPKGGPATPSPKG-APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS 1022
            T P    P+    PA  +PK  APT      P+    PA  + K APT      P+   S
Sbjct: 351  TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 410

Query: 1023 PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS-PKGGPATPSLKGAPT 1081
               TP     +T     P +PK  PA T   K APTTP    P+ PK    T + K APT
Sbjct: 411  APTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 469

Query: 1082 PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA-TPPSPKGGL 1140
                TP  P   P TP       P   TP +P+    T P K APTTP    P +P+   
Sbjct: 470  ----TPKEP--APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 523

Query: 1141 ATPPPKGAPTTP-AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1199
             T P + APTTP AA P +PK    T P + APTTP                + APTTP 
Sbjct: 524  PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK---------------EPAPTTPK 568

Query: 1200 ATPPS-PKGGLATPSPKGAPTTPAATPPSPKGGLATPSP------KGAPTTPAATPPS-P 1251
             T P+ PKG   T   + APTTP    P       T  P      K APTTP  T P+ P
Sbjct: 569  ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 628

Query: 1252 KGGPATPPPKGAPTPPAATPPS-LKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP 1310
            K    T P + APT P  T P+ LK    T P K  P P  + P + KG  +T+  K AP
Sbjct: 629  KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK--PAPKELAPTTTKGPTSTTSDKPAP 686

Query: 1311 TPPAATPPS-PKGSPGTPPPKGAPTPPAVTPP--SPKGTPTLPA--TTPSSKGGPTTPSS 1365
            T P  T P+ PK    T P K APT P   PP  S   TPT     TT       +TP  
Sbjct: 687  TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 746

Query: 1366 KEGPTPPAA--TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATP-VTR 1422
               PTP A   +P   G P    P+  + P + +   D T+   +  +P+   A P +T+
Sbjct: 747  SAEPTPKALENSPKEPGVPTTKTPAATK-PEMTTTAKDKTTERDLRTTPETTTAAPKMTK 805

Query: 1423 EGAATPSKG------------------DLTPPAVTPV----------SLKKAPATSAPKG 1454
            E A T  K                   D TP  +T +          + KK   T+    
Sbjct: 806  ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMN 865

Query: 1455 GPA-TPSSKGDPTLPAVTPPSPKEPP-APKQVATSSSPKKAPATPAPMGAPTLPAVIPSS 1512
             P  T   K   T    T P P++P  APK+  ++  PK  P    P   PT        
Sbjct: 866  KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPT-------- 917

Query: 1513 PKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPA 1572
                P   +S    + PT+ +       T  P +                  P  K    
Sbjct: 918  ----PRKMTSTMPELNPTSRIAEAMLQTTTRPNQT-----------------PNSKLVEV 956

Query: 1573 TPSSKEASSPPAVTP 1587
             P S++A      TP
Sbjct: 957  NPKSEDAGGAEGETP 971



 Score =  252 bits (643), Expect = 3e-66
 Identities = 284/995 (28%), Positives = 369/995 (37%), Gaps = 135/995 (13%)

Query: 553  TKKDPTVLPLV---QAAPKNSPSFQ------STSSSPEIPLSPEATLAKKSLGEP-LPIG 602
            TKK PT  P V     +  ++  F+      ST+   ++  SP+ T AK     P LP  
Sbjct: 74   TKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPN 133

Query: 603  KPASSMTSPLGVNSSASVI--------KTDSYAGPDSAGPLLKSSLITPT----VAAFPL 650
               S  TS L VN   +V         K  S  G +      ++  I  T    +A    
Sbjct: 134  SDTSKETS-LTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 192

Query: 651  ESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPV 710
              A P   A TT KG +  TT   P    T    P +   KE T TT+   PT     P 
Sbjct: 193  VLAKPTPKAETTTKGPAL-TTPKEP--TPTTPKEPASTTPKEPTPTTIKSAPTT----PK 245

Query: 711  APSPQNT-CAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKE 769
             P+P  T  AP      AP   K  P+P+ P    P  TK+           P  ++ K 
Sbjct: 246  EPAPTTTKSAPTTPKEPAPTTTKE-PAPTTPKEPAPTTTKE-----------PAPTTTKS 293

Query: 770  CPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVS 829
             PT     + T   K         P+P     +P+   P T K    P TP     +P +
Sbjct: 294  APTTPKEPAPTTPKK---------PAP----TTPKEPAPTTPKEPT-PTTP--KEPAPTT 337

Query: 830  PVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPS 889
               A   P+        K +P T   P P +PK    P+  T   P   T  PKE    +
Sbjct: 338  KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK---EPAPTTTKEPSPTT--PKEPAPTT 392

Query: 890  VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPS 949
              + P   + PA    K AP      ++PK+   T   +  P +P      TP    P +
Sbjct: 393  TKSAPTTTKEPAPTTTKSAP------TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 446

Query: 950  PKGG----PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSP-KGGPATPS 1004
            PK      P  P+P     P   TP  P   P TP      TP   TP +P K  P TP 
Sbjct: 447  PKEPAPTTPKEPAPTTTKKPAPTTPKEP--APTTPKETAPTTPKKLTPTTPEKLAPTTPE 504

Query: 1005 PKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKG-------SPAATPLPKGAP 1057
                 TP  + P +P+     TP     +TP AA P +PK         PA T   + AP
Sbjct: 505  KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 564

Query: 1058 TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGL 1117
            TTP  T               APT P  T P+    PA  +PK  P P    P + K   
Sbjct: 565  TTPKET---------------APTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTTKEPT 608

Query: 1118 ATPPHKGAPTTPAAT-PPSPKGGLATPPPKGAPTTPAATPPSP-KGGLATPPPKGAPTTP 1175
            +T   K APTTP  T P +PK    T P + APTTP  T P+  K    T P K AP   
Sbjct: 609  STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 668

Query: 1176 AATPPSPKGGLATPSPKGAPTTPAAT-PPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1234
            A  P + KG  +T S K APTTP  T P +PK    T   K APTTP  TPP     ++T
Sbjct: 669  A--PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVST 725

Query: 1235 PSPKGAPTTPAATP----------PSPKGGPATPPPKGAPT--PPAATPPSLKGGLATPP 1282
            P+    PTT   +P          P+PK    +P   G PT   PAAT P +     T  
Sbjct: 726  PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM---TTTAK 782

Query: 1283 HKGAPNPAVVTPPSPKGGP------ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP 1336
             K        TP +    P      AT+  K   +   AT      +          T  
Sbjct: 783  DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 842

Query: 1337 AVTPPSPKGTPTLP--ATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTP------PS 1388
              T  +PK T T     TT        T   K+  T   AT      P   P        
Sbjct: 843  KTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK 902

Query: 1389 PKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPA 1448
            PK  P +  PK  PT   +    P+  P + +      T ++ + TP +       K+  
Sbjct: 903  PKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSED 962

Query: 1449 TSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ 1483
                +G       +    +P VTP     P  P Q
Sbjct: 963  AGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQ 997



 Score =  224 bits (571), Expect = 7e-58
 Identities = 246/837 (29%), Positives = 330/837 (39%), Gaps = 123/837 (14%)

Query: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180
            P    P    A      G      P  + T       SPK   A P     P+ P  +  
Sbjct: 78   PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPI-NPRPSLPPNSDT 136

Query: 1181 SPKGGLA-----TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG-LAT 1234
            S +  L      T   K   TT   T    K    +     +    +A   +P    LA 
Sbjct: 137  SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 196

Query: 1235 PSPKGAPTT--PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV 1292
            P+PK   TT  PA T P  +  P TP    + TP   TP ++K    T P + AP     
Sbjct: 197  PTPKAETTTKGPALTTPK-EPTPTTPKEPASTTPKEPTPTTIKSA-PTTPKEPAPTTTKS 254

Query: 1293 TPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPAT 1352
             P +PK    T+  + APT P    P+    P     K APT P    P+   TP  PA 
Sbjct: 255  APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT---TPKKPAP 311

Query: 1353 TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP 1412
            T   +  PTTP      TP    P+ K     TP  P   P  P      T     P +P
Sbjct: 312  TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP--APTAPKKPAPTTPKEPAPTTP 369

Query: 1413 KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP 1472
            K+ PA   T+E + T      TP    P + K AP T+     PA  ++K  PT P    
Sbjct: 370  KE-PAPTTTKEPSPT------TPKEPAPTTTKSAPTTTKE---PAPTTTKSAPTTPKEPS 419

Query: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532
            P+  + PAP            P  PAP   P  PA  P++PKE PA P++ ++P APT T
Sbjct: 420  PTTTKEPAPT----------TPKEPAPT-TPKKPA--PTTPKE-PA-PTTPKEP-APTTT 463

Query: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE-APATPSSKEASSPPAVTPST-Y 1590
                K PA   PKE               PA  TPKE AP TP     ++P  + P+T  
Sbjct: 464  ----KKPAPTTPKE---------------PAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 504

Query: 1591 KGAPSPKELLIPPAVTSPSP----KEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSS 1646
            K AP+  E L P     P+P    + APT P    P+  K PA   PK    + P  P+ 
Sbjct: 505  KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA- 563

Query: 1647 LKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQT 1706
                PT+P         T P   KG      PT LKE    PAP +TP   AP    P T
Sbjct: 564  ----PTTPKE-------TAPTTPKGT----APTTLKE----PAP-TTPKKPAPKELAPTT 603

Query: 1707 KKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQ------KDSSKTAKGKDASHSPKG 1760
             K   ++    P P+   G+  P +   PAP  P +      K ++ T   + A  +PK 
Sbjct: 604  TKEPTSTTCDKPAPTTPKGT-APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 662

Query: 1761 P----LAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSP-VPTLPPKQQ 1815
            P    LAP  +K  T  T+       PK  + +    P+P  + P  P+P  P  PP   
Sbjct: 663  PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP--TTPKKPAPTTPETPPPTT 720

Query: 1816 FLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIP-VPT 1874
               S+P    E  +   +P   DE  P +  EP          L N  +PK  G+P   T
Sbjct: 721  SEVSTPTTTKEPTTIHKSP---DESTPELSAEPT------PKALEN--SPKEPGVPTTKT 769

Query: 1875 PSAKQP-VTKNNKGSGTESD------SDESVPEL--EEQDSTQATTQQAQLAAAAEI 1922
            P+A +P +T   K   TE D      +  + P++  E   +T+ TT+    A   ++
Sbjct: 770  PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 826



 Score =  208 bits (530), Expect = 4e-53
 Identities = 253/851 (29%), Positives = 325/851 (38%), Gaps = 128/851 (15%)

Query: 1166 PPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP-SPKGAPTTPAAT 1224
            P PK  P    A      G     +P  + T       SPK   A P +P+  P+ P  +
Sbjct: 78   PTPK-PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR--PSLPPNS 134

Query: 1225 PPSPKGGLA-----TPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLA 1279
              S +  L      T   K   TT   T  S  G   T   K   +    +   L     
Sbjct: 135  DTSKETSLTVNKETTVETKETTTTNKQT--STDGKEKTTSAKETQSIEKTSAKDL----- 187

Query: 1280 TPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVT 1339
                  AP   V+  P+PK    T  P    TP   TP +PK    T P +  PT     
Sbjct: 188  ------APTSKVLAKPTPKAETTTKGP-ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 240

Query: 1340 PPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK 1399
            P +PK     PA T ++K  PTTP      T     P+    PA   P+  + PA  + K
Sbjct: 241  PTTPKE----PAPT-TTKSAPTTPKEPAPTTTKEPAPTTPKEPA---PTTTKEPAPTTTK 292

Query: 1400 GDPTSPAV-IPLSPKK-APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPA 1457
              PT+P    P +PKK AP TP  +E A T  K         P    K PA + PK    
Sbjct: 293  SAPTTPKEPAPTTPKKPAPTTP--KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP 350

Query: 1458 TPSSKGDPTLPAV-TPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL---PAVIPSSP 1513
            T   K  PT P    P +PKEP        S +  K PA      APT    PA  P++ 
Sbjct: 351  TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA--PTTT 408

Query: 1514 KEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE-APA 1572
            K  P TP   ++P +PT T    K PA   PKE    PA T P   K PA  TPKE AP 
Sbjct: 409  KSAPTTP---KEP-SPTTT----KEPAPTTPKE----PAPTTP---KKPAPTTPKEPAPT 453

Query: 1573 TPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPA 1632
            TP        PA T +      +PKE    PA T+P      TP  +TP +PEK   T  
Sbjct: 454  TPKE------PAPTTTKKPAPTTPKE----PAPTTPKETAPTTPKKLTPTTPEKLAPTTP 503

Query: 1633 PKGTPTSP----PVTPSS-LKDSPTSPASVTCKMGA--TVPQASKGLPAKKGPTALKEVL 1685
             K  PT+P    P TP      +P  PA  T K  A  T  + +   P +  PT  KE  
Sbjct: 504  EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-- 561

Query: 1686 VAPAPESTPIITAPTR-KG--PQTKKSSATSPPICPDPS--AKNGSKGPLSTVAPAPLLP 1740
              PAP +TP  TAPT  KG  P T K  A + P  P P   A   +K P ST    P   
Sbjct: 562  --PAP-TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 618

Query: 1741 VQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSL 1800
              K ++ T   + A  +PK P AP   K + P T        P P +      P  P   
Sbjct: 619  TPKGTAPTTPKEPAPTTPKEP-APTTPKGTAPTTLKE-----PAPTT------PKKPAPK 666

Query: 1801 PLAPSPV--PTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSV 1858
             LAP+    PT     +  P++P        K  AP    E  P  P +P          
Sbjct: 667  ELAPTTTKGPTSTTSDKPAPTTP--------KETAPTTPKEPAPTTPKKPAP-------T 711

Query: 1859 LVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQ--- 1915
                P P ++ +  PT + K+P T            DES PEL  + + +A     +   
Sbjct: 712  TPETPPPTTSEVSTPT-TTKEPTT-------IHKSPDESTPELSAEPTPKALENSPKEPG 763

Query: 1916 ---LAAAAEIDEEPVSKAKQSRSEKKARKA-MSKLGLRQVTGVTRVTIRKSKNILFVITK 1971
                   A    E  + AK   +E+  R    +     ++T  T  T  K+       T 
Sbjct: 764  VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 823

Query: 1972 PDVYKSPASDT 1982
              V  +   DT
Sbjct: 824  TQVTSTTTQDT 834



 Score =  139 bits (350), Expect = 3e-32
 Identities = 149/561 (26%), Positives = 206/561 (36%), Gaps = 60/561 (10%)

Query: 1413 KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP 1472
            K  P  PV  E  +    GD         + +    +++PK   A P +      P++ P
Sbjct: 77   KPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR----PSLPP 132

Query: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532
             S         V   ++ +    T       T      +S KE  +   +    +APT+ 
Sbjct: 133  NSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 192

Query: 1533 LLSKKTPA--TLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590
            +L+K TP   T     AL  P    P+  K PA  TPKE   T      ++P    P+T 
Sbjct: 193  VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 252

Query: 1591 KGAP-SPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP----PVTPS 1645
            K AP +PKE   P   T+  P  APT P    P+  K PA    K  PT+P    P TP 
Sbjct: 253  KSAPTTPKE---PAPTTTKEP--APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 307

Query: 1646 S-LKDSPTSPASVTCKMGA-TVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKG 1703
                 +P  PA  T K    T P+       +  PT  KE   AP     P  T P    
Sbjct: 308  KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE--PAPTAPKKPAPTTPKEPA 365

Query: 1704 PQTKKSSA------TSPPICPDPSAKNGSKGPLSTVAPAPLL-----PVQKDSSKTAKGK 1752
            P T K  A       SP    +P+       P +T  PAP          K+ S T   +
Sbjct: 366  PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 425

Query: 1753 DASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSP------ 1806
             A  +PK P AP   K   P T        PK  + + +  P+P  + P  P+P      
Sbjct: 426  PAPTTPKEP-APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP--TTPKEPAPTTPKET 482

Query: 1807 VPTLPPKQQFLPSSP-GLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTP 1865
             PT P K    P++P  L   +P KP AP   +EL P  P E               PTP
Sbjct: 483  APTTPKK--LTPTTPEKLAPTTPEKP-APTTPEELAPTTPEE---------------PTP 524

Query: 1866 KSAGIPVP-TPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDE 1924
             +   P P TP A  P T       T  +   + P+     + + T        A    +
Sbjct: 525  TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 584

Query: 1925 EPVSKAKQSRSEKKARKAMSK 1945
            EP     +  + K+     +K
Sbjct: 585  EPAPTTPKKPAPKELAPTTTK 605



 Score =  139 bits (350), Expect = 3e-32
 Identities = 226/942 (23%), Positives = 331/942 (35%), Gaps = 138/942 (14%)

Query: 66  PFPSP-------STIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALAL 118
           P P P       S + +   +V  P +S+     + T+P+  T        PI+P     
Sbjct: 78  PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITT------AKPINPR---- 127

Query: 119 ASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAP 178
                 P+L     +S   +L      +V+       N  TS         G   T SA 
Sbjct: 128 ------PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTST-------DGKEKTTSAK 174

Query: 179 IAPSEPKTNLNKVPSEVVPNPK--GTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPT 236
              S  KT+      ++ P  K    P+P    +T      TP            + TPT
Sbjct: 175 ETQSIEKTSAK----DLAPTSKVLAKPTPKAETTTKGPALTTPK-----------EPTPT 219

Query: 237 TTLAIASPQVKD---TTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTA 293
           T    AS   K+   TTI S   +P+ P   + K   + P   + +T   P  T+ ++ A
Sbjct: 220 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA 279

Query: 294 GPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQ 353
              T    P +  S  AP             +  P+    P   T   + + T    P+ 
Sbjct: 280 PTTTKEPAPTTTKS--APTTPK---------EPAPTTPKKPA-PTTPKEPAPTTPKEPTP 327

Query: 354 RSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSL 413
            +   P P+  E  P T       AP+  K P+  +    +P+     A + +  P+ + 
Sbjct: 328 TTPKEPAPTTKEPAPTTPKE---PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 384

Query: 414 ILKSSPNATYHYPLVAQMPV----SSVGTTPLVVTNPCTIAAAPTTTFEVATCV------ 463
             + +P  T   P   + P      S  TTP   +   T   APTT  E A         
Sbjct: 385 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 444

Query: 464 --------SPPMSSGPISNIEPTSPAALVMAPVAPKE--PSTQVATTLRIP--VSPPLPD 511
                   + P    P +  +P        AP  PKE  P+T    T   P  ++P  P+
Sbjct: 445 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 504

Query: 512 PEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSP 571
               K  P++     PT  +  T     E AP +P  A   T K+P      + AP    
Sbjct: 505 ----KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 560

Query: 572 SFQSTSSSPEIPLSPEATLAKKSLGEPLPI--GKPASSMTSPLGVNSSASVIKTDSYAGP 629
               T+     P +P+ T A  +L EP P    KPA    +P       +  K  +    
Sbjct: 561 EPAPTTPKETAPTTPKGT-APTTLKEPAPTTPKKPAPKELAP-------TTTKEPTSTTC 612

Query: 630 DSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHP 689
           D   P        PT    P  +  P   APTT KGT+  T      L+      PK   
Sbjct: 613 DKPAPTTPKG-TAPTTPKEPAPTT-PKEPAPTTPKGTAPTT------LKEPAPTTPKKPA 664

Query: 690 VKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTK 749
            KE   TT    PT++ +   AP+     AP      AP  PK  P+P+ P    PP T 
Sbjct: 665 PKELAPTTTK-GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK-PAPTTPET-PPPTTS 721

Query: 750 KVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPP 809
           +V   + T     +  SP E   E        S++ T   L +SP   GV   P TK P 
Sbjct: 722 EVSTPTTTKEPTTIHKSPDESTPE-------LSAEPTPKALENSPKEPGV---PTTKTPA 771

Query: 810 TKKGSAGP------------DTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT 857
             K                  TP    ++P    E +   E +   + +  +   T + T
Sbjct: 772 ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTT 831

Query: 858 PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP---ATPAPKQAPALSMT 914
             +     T    T L+PK VT   K   T  ++N P     P   AT +    P     
Sbjct: 832 QDTTPFKITTLKTTTLAPK-VTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKP 890

Query: 915 SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT 956
           + +PKK  +T  PK +P    PK  PTP   T   P+  P +
Sbjct: 891 TKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTS 932



 Score =  119 bits (299), Expect = 2e-26
 Identities = 189/790 (23%), Positives = 276/790 (34%), Gaps = 98/790 (12%)

Query: 6   TETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQAS 65
           T+++  T  +   P ++    P   A + T      GP L  P  P P   P   A+   
Sbjct: 176 TQSIEKTSAKDLAPTSKVLAKPTPKAETTTK-----GPALTTPKEPTPTT-PKEPASTTP 229

Query: 66  PFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTF----LPNLIGPPISPAALALASP 121
             P+P+TI S P     P  ++  + P      APT      P     P +P      +P
Sbjct: 230 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP-APTTTKEPAP 288

Query: 122 MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAP 181
               +   TP   AP      AP + ++ +   P     P      E        AP  P
Sbjct: 289 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK---EPTPTTPKEPAPTTKEPAPTTP 345

Query: 182 SEPKTNLNKVPSEVVPNPKG--TPSPPCIVSTVPYHCVTPMASIQSGVASLPQTT----P 235
            EP     K P+   P      TP  P   +T      TP     +   S P TT    P
Sbjct: 346 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 405

Query: 236 TTTLAIASPQVK---DTTISSVLISPQNPGSLSLKGPV-SPPAALSLSTQSLPVVTSSQK 291
           TTT +  +   +    TT      +P+ P   + K P  + P   + +T   P  T+++K
Sbjct: 406 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 465

Query: 292 TAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPT----VKTISVDHSSTG 347
            A P TP +   +     AP       + + L  T P  L+  T      T   + + T 
Sbjct: 466 PA-PTTPKEPAPTTPKETAPT------TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 518

Query: 348 ASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSL 407
              P+  +   P P+  +         P  AP+  K P+  +    +P+      T    
Sbjct: 519 PEEPTPTTPEEPAPTTPKAAAPNTPKEP--APTTPKEPAPTTPKEPAPT------TPKET 570

Query: 408 SPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFE--VATCVSP 465
           +PTT       P  T    L    P     TTP     P     APTTT E    TC  P
Sbjct: 571 APTT-------PKGTAPTTLKEPAP-----TTP---KKPAPKELAPTTTKEPTSTTCDKP 615

Query: 466 -PMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLR--IPVSPPLPDPEDLKNLPSSV 522
            P +    +   P  PA       AP  P     TTL+   P +P  P P++L    +  
Sbjct: 616 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 675

Query: 523 LVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQST------ 576
                + K   T P   E AP +P +   TT K P   P     P  + S  ST      
Sbjct: 676 PTSTTSDKPAPTTPK--ETAPTTPKEPAPTTPKKPA--PTTPETPPPTTSEVSTPTTTKE 731

Query: 577 ---------SSSPEIPLSPEATLAKKSLGEP-LPIGKPASSMTSPLGVNSSASVIKTDSY 626
                     S+PE+   P     + S  EP +P  K  ++    +   +     + D  
Sbjct: 732 PTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLR 791

Query: 627 AGPD--SAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPF---LEGTV 681
             P+  +A P +     T T      E    + +  TT + TST T   +PF      T 
Sbjct: 792 TTPETTTAAPKMTKETATTT------EKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 845

Query: 682 SLAPKNHPVKEGTLTTLPLVPTASENCPV---APSPQNTCAPLATLVLAPEIPKSVPSPS 738
           +LAPK    K+ T+TT  ++    E       A + + T         AP+ P S   P 
Sbjct: 846 TLAPKVTTTKK-TITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPK 904

Query: 739 LPPAGTPPGT 748
             P    P T
Sbjct: 905 TMPRVRKPKT 914



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 70/280 (25%), Positives = 99/280 (35%), Gaps = 25/280 (8%)

Query: 2   PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
           P    E  P T +E P P       P +   +      +P PT P   +P   + P    
Sbjct: 508 PTTPEELAPTTPEE-PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 566

Query: 62  NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAP---EAPTFLPNLIGPPISPAALAL 118
            + +   +P   A T L+ P P +    A P   AP   + PT        P +P   A 
Sbjct: 567 PKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625

Query: 119 ASPM-IAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSA 177
            +P   APT   TP   AP      AP ++++ +   P              G   T S 
Sbjct: 626 TTPKEPAPT---TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 682

Query: 178 PIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTT 237
             AP+ PK      P E  P     P+P     T P    TP  +  +   S P TT   
Sbjct: 683 KPAPTTPKETAPTTPKEPAPTTPKKPAP-----TTP---ETPPPT--TSEVSTPTTTKEP 732

Query: 238 TLAIASPQVK------DTTISSVLISPQNPGSLSLKGPVS 271
           T    SP         + T  ++  SP+ PG  + K P +
Sbjct: 733 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 772



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 73/309 (23%), Positives = 116/309 (37%), Gaps = 47/309 (15%)

Query: 3   GEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAAN 62
           G A  T+       P+  A   + P ++    +    +P PT P   +P   + P     
Sbjct: 577 GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTP 636

Query: 63  QASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPM 122
           +     +P   A T L+ P P           T P+ P   P  + P  +    +  S  
Sbjct: 637 KEPAPTTPKGTAPTTLKEPAP-----------TTPKKPA--PKELAPTTTKGPTSTTSDK 683

Query: 123 IAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPS 182
            APT   TP  +AP      AP + +K +   P   T PP+ +         +S P    
Sbjct: 684 PAPT---TPKETAPTTPKEPAPTTPKKPAPTTPE--TPPPTTS--------EVSTPTTTK 730

Query: 183 EPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCV----TPMASIQSGVASLP------- 231
           EP T ++K P E  P     P+P  + ++     V    TP A+      +         
Sbjct: 731 EP-TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 789

Query: 232 -QTTPTTTLAIASPQVKDT------TISSVLISPQNPGSLSLKGPVSPPAALSLSTQSL- 283
            +TTP TT A A    K+T      T  S + +     + +     +P    +L T +L 
Sbjct: 790 LRTTPETTTA-APKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLA 848

Query: 284 PVVTSSQKT 292
           P VT+++KT
Sbjct: 849 PKVTTTKKT 857


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score =  300 bits (767), Expect = 1e-80
 Identities = 288/904 (31%), Positives = 378/904 (41%), Gaps = 109/904 (12%)

Query: 848  DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907
            D+  T H+    SPK     +   P++P+  +LPP  + T    +L   KE   T   K+
Sbjct: 144  DTSTTQHNKVSTSPK----ITTAKPINPRP-SLPPN-SDTSKETSLTVNKE--TTVETKE 195

Query: 908  APALSMTSSSPKKARATPAPK--GIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965
                +  +S+  K + T A +   I  + +   APT      P+PK    T  P    TP
Sbjct: 196  TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT-TP 254

Query: 966  PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAA 1025
               TP +PK   +T       TP   TP + K  P TP  + APT     P +PK  PA 
Sbjct: 255  KEPTPTTPKEPAST-------TPKEPTPTTIKSAPTTPK-EPAPTTTKSAPTTPK-EPAP 305

Query: 1026 TPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS--PKGGPATPSLKGAPTPP 1083
            T   + A T P    P+    PA T   K APTTP    P+   K  P TP      TP 
Sbjct: 306  TTTKEPAPTTPKEPAPTTTKEPAPT-TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 364

Query: 1084 AATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP-AATPPSPKGGLAT 1142
              TP +PK        + AP      P +PK    T P K APTTP    P +PK    T
Sbjct: 365  EPTPTTPK--------EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 416

Query: 1143 PPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1202
               + +PTTP    P+      T   + APTT  + P +PK    T + + APTTP    
Sbjct: 417  TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 476

Query: 1203 PSPKGGLATPSPKGAPTTP-AATPPSPKGGLATPSPKGAPTTP-AATPPSPKGGPATPPP 1260
            P       T   K APTTP    P +PK    T + K APTTP    P +PK    T P 
Sbjct: 477  P-------TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 529

Query: 1261 KGAPTPPAATPPSLKGGLATPPHKGAP-NPAVVTPPSPKGGPATSPPKGAP-TPPAATPP 1318
            K  PT P    P       T P K AP  P  + P +P+    T+P + AP TP AA P 
Sbjct: 530  KLTPTTPEKLAP-------TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN 582

Query: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378
            +PK    T P + APT    TP  P   PT P  T  +    T P++ + P P   TP  
Sbjct: 583  TPKEPAPTTPKEPAPT----TPKEP--APTTPKETAPTTPKGTAPTTLKEPAP--TTPKK 634

Query: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSP-AVIPLSPKK-APATPVTREGAATPSKG----D 1432
                 + P + K   +    K  PT+P    P +PK+ AP TP  +E A T  KG     
Sbjct: 635  PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTP--KEPAPTTPKGTAPTT 692

Query: 1433 LTPPAVTPVSLKKAPATSAP---KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSS 1489
            L  PA T    K AP   AP   KG  +T S K  PT P  T P+  + PAP      ++
Sbjct: 693  LKEPAPT-TPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP------TT 745

Query: 1490 PKK-APATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL--APKE 1546
            PKK AP TP      T     P++ KE P T    + P   T  L ++ TP  L  +PKE
Sbjct: 746  PKKPAPTTPETPPPTTSEVSTPTTTKE-PTT--IHKSPDESTPELSAEPTPKALENSPKE 802

Query: 1547 ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPS-PKELLIPPAV 1605
              +P         KTPA   P E   T   K        TP T   AP   KE       
Sbjct: 803  PGVPTT-------KTPAATKP-EMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 854

Query: 1606 TSPSPKEAPTPPAVTPPSPEKGP--------ATPAPKGTPTSPPVTPSSLKDSP---TSP 1654
            T+ S   A T    +  + +  P         T APK T T   +T + + + P     P
Sbjct: 855  TTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKP 914

Query: 1655 ASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSP 1714
                    AT P+  K   A K PT+ K+      P++ P +  P +  P  +K ++T P
Sbjct: 915  KDRATNSKATTPKPQKPTKAPKKPTSTKK------PKTMPRVRKP-KTTPTPRKMTSTMP 967

Query: 1715 PICP 1718
             + P
Sbjct: 968  ELNP 971



 Score =  285 bits (728), Expect = 4e-76
 Identities = 278/915 (30%), Positives = 356/915 (38%), Gaps = 131/915 (14%)

Query: 735  PSPSLPP-AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADS 793
            P PSLPP + T   T        T       ++ K+  T+  G   T S+K T +    S
Sbjct: 167  PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTD--GKEKTTSAKETQSIEKTS 224

Query: 794  PSPLG----VSVSPQTKRPPTKKGSA--GPDTPIGNLSSPVSPVEASFLPENSLSFQGSK 847
               L     V   P  K   T KG A   P  P     +P +P E +       +    K
Sbjct: 225  AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP-----TPTTPKEPASTTPKEPTPTTIK 279

Query: 848  DSPATTHSPTPPSPKGAPT----PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903
             +P T   P P + K APT    P+  T   P   T  PKE P P+    P P    + P
Sbjct: 280  SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT--PKE-PAPTTTKEPAPTTTKSAP 336

Query: 904  APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963
               + PA     ++PKK   T   +  P +P      TP    P + +  P TP    AP
Sbjct: 337  TTPKEPA----PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP-AP 391

Query: 964  TPPAATPPSPKGGPATPSPKG-APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS 1022
            T P    P+    PA  +PK  APT      P+    PA  + K APT      P+   S
Sbjct: 392  TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 451

Query: 1023 PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS-PKGGPATPSLKGAPT 1081
               TP     +T     P +PK  PA T   K APTTP    P+ PK    T + K APT
Sbjct: 452  APTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 510

Query: 1082 PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA-TPPSPKGGL 1140
                TP  P   P TP       P   TP +P+    T P K APTTP    P +P+   
Sbjct: 511  ----TPKEP--APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 564

Query: 1141 ATPPPKGAPTTP-AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1199
             T P + APTTP AA P +PK    T P + APTTP                + APTTP 
Sbjct: 565  PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK---------------EPAPTTPK 609

Query: 1200 ATPPS-PKGGLATPSPKGAPTTPAATPPSPKGGLATPSP------KGAPTTPAATPPS-P 1251
             T P+ PKG   T   + APTTP    P       T  P      K APTTP  T P+ P
Sbjct: 610  ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 669

Query: 1252 KGGPATPPPKGAPTPPAATPPS-LKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP 1310
            K    T P + APT P  T P+ LK    T P K  P P  + P + KG  +T+  K AP
Sbjct: 670  KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK--PAPKELAPTTTKGPTSTTSDKPAP 727

Query: 1311 TPPAATPPS-PKGSPGTPPPKGAPTPPAVTPP--SPKGTPTLPA--TTPSSKGGPTTPSS 1365
            T P  T P+ PK    T P K APT P   PP  S   TPT     TT       +TP  
Sbjct: 728  TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 787

Query: 1366 KEGPTPPAA--TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATP-VTR 1422
               PTP A   +P   G P    P+  + P + +   D T+   +  +P+   A P +T+
Sbjct: 788  SAEPTPKALENSPKEPGVPTTKTPAATK-PEMTTTAKDKTTERDLRTTPETTTAAPKMTK 846

Query: 1423 EGAATPSKG------------------DLTPPAVTPV----------SLKKAPATSAPKG 1454
            E A T  K                   D TP  +T +          + KK   T+    
Sbjct: 847  ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMN 906

Query: 1455 GPA-TPSSKGDPTLPAVTPPSPKEPP-APKQVATSSSPKKAPATPAPMGAPTLPAVIPSS 1512
             P  T   K   T    T P P++P  APK+  ++  PK  P    P   PT        
Sbjct: 907  KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPT-------- 958

Query: 1513 PKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPA 1572
                P   +S    + PT+ +       T  P +                  P  K    
Sbjct: 959  ----PRKMTSTMPELNPTSRIAEAMLQTTTRPNQT-----------------PNSKLVEV 997

Query: 1573 TPSSKEASSPPAVTP 1587
             P S++A      TP
Sbjct: 998  NPKSEDAGGAEGETP 1012



 Score =  252 bits (643), Expect = 3e-66
 Identities = 284/995 (28%), Positives = 369/995 (37%), Gaps = 135/995 (13%)

Query: 553  TKKDPTVLPLV---QAAPKNSPSFQ------STSSSPEIPLSPEATLAKKSLGEP-LPIG 602
            TKK PT  P V     +  ++  F+      ST+   ++  SP+ T AK     P LP  
Sbjct: 115  TKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPN 174

Query: 603  KPASSMTSPLGVNSSASVI--------KTDSYAGPDSAGPLLKSSLITPT----VAAFPL 650
               S  TS L VN   +V         K  S  G +      ++  I  T    +A    
Sbjct: 175  SDTSKETS-LTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 233

Query: 651  ESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPV 710
              A P   A TT KG +  TT   P    T    P +   KE T TT+   PT     P 
Sbjct: 234  VLAKPTPKAETTTKGPAL-TTPKEP--TPTTPKEPASTTPKEPTPTTIKSAPTT----PK 286

Query: 711  APSPQNT-CAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKE 769
             P+P  T  AP      AP   K  P+P+ P    P  TK+           P  ++ K 
Sbjct: 287  EPAPTTTKSAPTTPKEPAPTTTKE-PAPTTPKEPAPTTTKE-----------PAPTTTKS 334

Query: 770  CPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVS 829
             PT     + T   K         P+P     +P+   P T K    P TP     +P +
Sbjct: 335  APTTPKEPAPTTPKK---------PAP----TTPKEPAPTTPKEPT-PTTP--KEPAPTT 378

Query: 830  PVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPS 889
               A   P+        K +P T   P P +PK    P+  T   P   T  PKE    +
Sbjct: 379  KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK---EPAPTTTKEPSPTT--PKEPAPTT 433

Query: 890  VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPS 949
              + P   + PA    K AP      ++PK+   T   +  P +P      TP    P +
Sbjct: 434  TKSAPTTTKEPAPTTTKSAP------TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 487

Query: 950  PKGG----PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSP-KGGPATPS 1004
            PK      P  P+P     P   TP  P   P TP      TP   TP +P K  P TP 
Sbjct: 488  PKEPAPTTPKEPAPTTTKKPAPTTPKEP--APTTPKETAPTTPKKLTPTTPEKLAPTTPE 545

Query: 1005 PKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKG-------SPAATPLPKGAP 1057
                 TP  + P +P+     TP     +TP AA P +PK         PA T   + AP
Sbjct: 546  KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 605

Query: 1058 TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGL 1117
            TTP  T               APT P  T P+    PA  +PK  P P    P + K   
Sbjct: 606  TTPKET---------------APTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTTKEPT 649

Query: 1118 ATPPHKGAPTTPAAT-PPSPKGGLATPPPKGAPTTPAATPPSP-KGGLATPPPKGAPTTP 1175
            +T   K APTTP  T P +PK    T P + APTTP  T P+  K    T P K AP   
Sbjct: 650  STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 709

Query: 1176 AATPPSPKGGLATPSPKGAPTTPAAT-PPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1234
            A  P + KG  +T S K APTTP  T P +PK    T   K APTTP  TPP     ++T
Sbjct: 710  A--PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVST 766

Query: 1235 PSPKGAPTTPAATP----------PSPKGGPATPPPKGAPT--PPAATPPSLKGGLATPP 1282
            P+    PTT   +P          P+PK    +P   G PT   PAAT P +     T  
Sbjct: 767  PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM---TTTAK 823

Query: 1283 HKGAPNPAVVTPPSPKGGP------ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP 1336
             K        TP +    P      AT+  K   +   AT      +          T  
Sbjct: 824  DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 883

Query: 1337 AVTPPSPKGTPTLP--ATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTP------PS 1388
              T  +PK T T     TT        T   K+  T   AT      P   P        
Sbjct: 884  KTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK 943

Query: 1389 PKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPA 1448
            PK  P +  PK  PT   +    P+  P + +      T ++ + TP +       K+  
Sbjct: 944  PKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSED 1003

Query: 1449 TSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ 1483
                +G       +    +P VTP     P  P Q
Sbjct: 1004 AGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQ 1038



 Score =  224 bits (571), Expect = 7e-58
 Identities = 246/837 (29%), Positives = 330/837 (39%), Gaps = 123/837 (14%)

Query: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180
            P    P    A      G      P  + T       SPK   A P     P+ P  +  
Sbjct: 119  PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPI-NPRPSLPPNSDT 177

Query: 1181 SPKGGLA-----TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG-LAT 1234
            S +  L      T   K   TT   T    K    +     +    +A   +P    LA 
Sbjct: 178  SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 237

Query: 1235 PSPKGAPTT--PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV 1292
            P+PK   TT  PA T P  +  P TP    + TP   TP ++K    T P + AP     
Sbjct: 238  PTPKAETTTKGPALTTPK-EPTPTTPKEPASTTPKEPTPTTIKSA-PTTPKEPAPTTTKS 295

Query: 1293 TPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPAT 1352
             P +PK    T+  + APT P    P+    P     K APT P    P+   TP  PA 
Sbjct: 296  APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT---TPKKPAP 352

Query: 1353 TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP 1412
            T   +  PTTP      TP    P+ K     TP  P   P  P      T     P +P
Sbjct: 353  TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP--APTAPKKPAPTTPKEPAPTTP 410

Query: 1413 KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP 1472
            K+ PA   T+E + T      TP    P + K AP T+     PA  ++K  PT P    
Sbjct: 411  KE-PAPTTTKEPSPT------TPKEPAPTTTKSAPTTTKE---PAPTTTKSAPTTPKEPS 460

Query: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532
            P+  + PAP            P  PAP   P  PA  P++PKE PA P++ ++P APT T
Sbjct: 461  PTTTKEPAPT----------TPKEPAPT-TPKKPA--PTTPKE-PA-PTTPKEP-APTTT 504

Query: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE-APATPSSKEASSPPAVTPST-Y 1590
                K PA   PKE               PA  TPKE AP TP     ++P  + P+T  
Sbjct: 505  ----KKPAPTTPKE---------------PAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 545

Query: 1591 KGAPSPKELLIPPAVTSPSP----KEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSS 1646
            K AP+  E L P     P+P    + APT P    P+  K PA   PK    + P  P+ 
Sbjct: 546  KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA- 604

Query: 1647 LKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQT 1706
                PT+P         T P   KG      PT LKE    PAP +TP   AP    P T
Sbjct: 605  ----PTTPKE-------TAPTTPKGT----APTTLKE----PAP-TTPKKPAPKELAPTT 644

Query: 1707 KKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQ------KDSSKTAKGKDASHSPKG 1760
             K   ++    P P+   G+  P +   PAP  P +      K ++ T   + A  +PK 
Sbjct: 645  TKEPTSTTCDKPAPTTPKGT-APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 703

Query: 1761 P----LAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSP-VPTLPPKQQ 1815
            P    LAP  +K  T  T+       PK  + +    P+P  + P  P+P  P  PP   
Sbjct: 704  PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP--TTPKKPAPTTPETPPPTT 761

Query: 1816 FLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIP-VPT 1874
               S+P    E  +   +P   DE  P +  EP          L N  +PK  G+P   T
Sbjct: 762  SEVSTPTTTKEPTTIHKSP---DESTPELSAEPT------PKALEN--SPKEPGVPTTKT 810

Query: 1875 PSAKQP-VTKNNKGSGTESD------SDESVPEL--EEQDSTQATTQQAQLAAAAEI 1922
            P+A +P +T   K   TE D      +  + P++  E   +T+ TT+    A   ++
Sbjct: 811  PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 867



 Score =  208 bits (530), Expect = 4e-53
 Identities = 253/851 (29%), Positives = 325/851 (38%), Gaps = 128/851 (15%)

Query: 1166 PPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP-SPKGAPTTPAAT 1224
            P PK  P    A      G     +P  + T       SPK   A P +P+  P+ P  +
Sbjct: 119  PTPK-PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR--PSLPPNS 175

Query: 1225 PPSPKGGLA-----TPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLA 1279
              S +  L      T   K   TT   T  S  G   T   K   +    +   L     
Sbjct: 176  DTSKETSLTVNKETTVETKETTTTNKQT--STDGKEKTTSAKETQSIEKTSAKDL----- 228

Query: 1280 TPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVT 1339
                  AP   V+  P+PK    T  P    TP   TP +PK    T P +  PT     
Sbjct: 229  ------APTSKVLAKPTPKAETTTKGP-ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 281

Query: 1340 PPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK 1399
            P +PK     PA T ++K  PTTP      T     P+    PA   P+  + PA  + K
Sbjct: 282  PTTPKE----PAPT-TTKSAPTTPKEPAPTTTKEPAPTTPKEPA---PTTTKEPAPTTTK 333

Query: 1400 GDPTSPAV-IPLSPKK-APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPA 1457
              PT+P    P +PKK AP TP  +E A T  K         P    K PA + PK    
Sbjct: 334  SAPTTPKEPAPTTPKKPAPTTP--KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP 391

Query: 1458 TPSSKGDPTLPAV-TPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL---PAVIPSSP 1513
            T   K  PT P    P +PKEP        S +  K PA      APT    PA  P++ 
Sbjct: 392  TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA--PTTT 449

Query: 1514 KEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE-APA 1572
            K  P TP   ++P +PT T    K PA   PKE    PA T P   K PA  TPKE AP 
Sbjct: 450  KSAPTTP---KEP-SPTTT----KEPAPTTPKE----PAPTTP---KKPAPTTPKEPAPT 494

Query: 1573 TPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPA 1632
            TP        PA T +      +PKE    PA T+P      TP  +TP +PEK   T  
Sbjct: 495  TPKE------PAPTTTKKPAPTTPKE----PAPTTPKETAPTTPKKLTPTTPEKLAPTTP 544

Query: 1633 PKGTPTSP----PVTPSS-LKDSPTSPASVTCKMGA--TVPQASKGLPAKKGPTALKEVL 1685
             K  PT+P    P TP      +P  PA  T K  A  T  + +   P +  PT  KE  
Sbjct: 545  EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-- 602

Query: 1686 VAPAPESTPIITAPTR-KG--PQTKKSSATSPPICPDPS--AKNGSKGPLSTVAPAPLLP 1740
              PAP +TP  TAPT  KG  P T K  A + P  P P   A   +K P ST    P   
Sbjct: 603  --PAP-TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 659

Query: 1741 VQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSL 1800
              K ++ T   + A  +PK P AP   K + P T        P P +      P  P   
Sbjct: 660  TPKGTAPTTPKEPAPTTPKEP-APTTPKGTAPTTLKE-----PAPTT------PKKPAPK 707

Query: 1801 PLAPSPV--PTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSV 1858
             LAP+    PT     +  P++P        K  AP    E  P  P +P          
Sbjct: 708  ELAPTTTKGPTSTTSDKPAPTTP--------KETAPTTPKEPAPTTPKKPAP-------T 752

Query: 1859 LVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQ--- 1915
                P P ++ +  PT + K+P T            DES PEL  + + +A     +   
Sbjct: 753  TPETPPPTTSEVSTPT-TTKEPTT-------IHKSPDESTPELSAEPTPKALENSPKEPG 804

Query: 1916 ---LAAAAEIDEEPVSKAKQSRSEKKARKA-MSKLGLRQVTGVTRVTIRKSKNILFVITK 1971
                   A    E  + AK   +E+  R    +     ++T  T  T  K+       T 
Sbjct: 805  VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 864

Query: 1972 PDVYKSPASDT 1982
              V  +   DT
Sbjct: 865  TQVTSTTTQDT 875



 Score =  139 bits (350), Expect = 3e-32
 Identities = 149/561 (26%), Positives = 206/561 (36%), Gaps = 60/561 (10%)

Query: 1413 KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP 1472
            K  P  PV  E  +    GD         + +    +++PK   A P +      P++ P
Sbjct: 118  KPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR----PSLPP 173

Query: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532
             S         V   ++ +    T       T      +S KE  +   +    +APT+ 
Sbjct: 174  NSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 233

Query: 1533 LLSKKTPA--TLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590
            +L+K TP   T     AL  P    P+  K PA  TPKE   T      ++P    P+T 
Sbjct: 234  VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 293

Query: 1591 KGAP-SPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP----PVTPS 1645
            K AP +PKE   P   T+  P  APT P    P+  K PA    K  PT+P    P TP 
Sbjct: 294  KSAPTTPKE---PAPTTTKEP--APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 348

Query: 1646 S-LKDSPTSPASVTCKMGA-TVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKG 1703
                 +P  PA  T K    T P+       +  PT  KE   AP     P  T P    
Sbjct: 349  KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE--PAPTAPKKPAPTTPKEPA 406

Query: 1704 PQTKKSSA------TSPPICPDPSAKNGSKGPLSTVAPAPLL-----PVQKDSSKTAKGK 1752
            P T K  A       SP    +P+       P +T  PAP          K+ S T   +
Sbjct: 407  PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 466

Query: 1753 DASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSP------ 1806
             A  +PK P AP   K   P T        PK  + + +  P+P  + P  P+P      
Sbjct: 467  PAPTTPKEP-APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP--TTPKEPAPTTPKET 523

Query: 1807 VPTLPPKQQFLPSSP-GLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTP 1865
             PT P K    P++P  L   +P KP AP   +EL P  P E               PTP
Sbjct: 524  APTTPKK--LTPTTPEKLAPTTPEKP-APTTPEELAPTTPEE---------------PTP 565

Query: 1866 KSAGIPVP-TPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDE 1924
             +   P P TP A  P T       T  +   + P+     + + T        A    +
Sbjct: 566  TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 625

Query: 1925 EPVSKAKQSRSEKKARKAMSK 1945
            EP     +  + K+     +K
Sbjct: 626  EPAPTTPKKPAPKELAPTTTK 646



 Score =  139 bits (350), Expect = 3e-32
 Identities = 226/942 (23%), Positives = 331/942 (35%), Gaps = 138/942 (14%)

Query: 66  PFPSP-------STIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALAL 118
           P P P       S + +   +V  P +S+     + T+P+  T        PI+P     
Sbjct: 119 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITT------AKPINPR---- 168

Query: 119 ASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAP 178
                 P+L     +S   +L      +V+       N  TS         G   T SA 
Sbjct: 169 ------PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTST-------DGKEKTTSAK 215

Query: 179 IAPSEPKTNLNKVPSEVVPNPK--GTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPT 236
              S  KT+      ++ P  K    P+P    +T      TP            + TPT
Sbjct: 216 ETQSIEKTSAK----DLAPTSKVLAKPTPKAETTTKGPALTTPK-----------EPTPT 260

Query: 237 TTLAIASPQVKD---TTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTA 293
           T    AS   K+   TTI S   +P+ P   + K   + P   + +T   P  T+ ++ A
Sbjct: 261 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA 320

Query: 294 GPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQ 353
              T    P +  S  AP             +  P+    P   T   + + T    P+ 
Sbjct: 321 PTTTKEPAPTTTKS--APTTPK---------EPAPTTPKKPA-PTTPKEPAPTTPKEPTP 368

Query: 354 RSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSL 413
            +   P P+  E  P T       AP+  K P+  +    +P+     A + +  P+ + 
Sbjct: 369 TTPKEPAPTTKEPAPTTPKE---PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 425

Query: 414 ILKSSPNATYHYPLVAQMPV----SSVGTTPLVVTNPCTIAAAPTTTFEVATCV------ 463
             + +P  T   P   + P      S  TTP   +   T   APTT  E A         
Sbjct: 426 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 485

Query: 464 --------SPPMSSGPISNIEPTSPAALVMAPVAPKE--PSTQVATTLRIP--VSPPLPD 511
                   + P    P +  +P        AP  PKE  P+T    T   P  ++P  P+
Sbjct: 486 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 545

Query: 512 PEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSP 571
               K  P++     PT  +  T     E AP +P  A   T K+P      + AP    
Sbjct: 546 ----KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 601

Query: 572 SFQSTSSSPEIPLSPEATLAKKSLGEPLPI--GKPASSMTSPLGVNSSASVIKTDSYAGP 629
               T+     P +P+ T A  +L EP P    KPA    +P       +  K  +    
Sbjct: 602 EPAPTTPKETAPTTPKGT-APTTLKEPAPTTPKKPAPKELAP-------TTTKEPTSTTC 653

Query: 630 DSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHP 689
           D   P        PT    P  +  P   APTT KGT+  T      L+      PK   
Sbjct: 654 DKPAPTTPKG-TAPTTPKEPAPTT-PKEPAPTTPKGTAPTT------LKEPAPTTPKKPA 705

Query: 690 VKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTK 749
            KE   TT    PT++ +   AP+     AP      AP  PK  P+P+ P    PP T 
Sbjct: 706 PKELAPTTTK-GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK-PAPTTPET-PPPTTS 762

Query: 750 KVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPP 809
           +V   + T     +  SP E   E        S++ T   L +SP   GV   P TK P 
Sbjct: 763 EVSTPTTTKEPTTIHKSPDESTPE-------LSAEPTPKALENSPKEPGV---PTTKTPA 812

Query: 810 TKKGSAGP------------DTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT 857
             K                  TP    ++P    E +   E +   + +  +   T + T
Sbjct: 813 ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTT 872

Query: 858 PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP---ATPAPKQAPALSMT 914
             +     T    T L+PK VT   K   T  ++N P     P   AT +    P     
Sbjct: 873 QDTTPFKITTLKTTTLAPK-VTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKP 931

Query: 915 SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT 956
           + +PKK  +T  PK +P    PK  PTP   T   P+  P +
Sbjct: 932 TKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTS 973



 Score =  119 bits (299), Expect = 2e-26
 Identities = 189/790 (23%), Positives = 276/790 (34%), Gaps = 98/790 (12%)

Query: 6   TETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQAS 65
           T+++  T  +   P ++    P   A + T      GP L  P  P P   P   A+   
Sbjct: 217 TQSIEKTSAKDLAPTSKVLAKPTPKAETTTK-----GPALTTPKEPTPTT-PKEPASTTP 270

Query: 66  PFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTF----LPNLIGPPISPAALALASP 121
             P+P+TI S P     P  ++  + P      APT      P     P +P      +P
Sbjct: 271 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP-APTTTKEPAP 329

Query: 122 MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAP 181
               +   TP   AP      AP + ++ +   P     P      E        AP  P
Sbjct: 330 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK---EPTPTTPKEPAPTTKEPAPTTP 386

Query: 182 SEPKTNLNKVPSEVVPNPKG--TPSPPCIVSTVPYHCVTPMASIQSGVASLPQTT----P 235
            EP     K P+   P      TP  P   +T      TP     +   S P TT    P
Sbjct: 387 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 446

Query: 236 TTTLAIASPQVK---DTTISSVLISPQNPGSLSLKGPV-SPPAALSLSTQSLPVVTSSQK 291
           TTT +  +   +    TT      +P+ P   + K P  + P   + +T   P  T+++K
Sbjct: 447 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 506

Query: 292 TAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPT----VKTISVDHSSTG 347
            A P TP +   +     AP       + + L  T P  L+  T      T   + + T 
Sbjct: 507 PA-PTTPKEPAPTTPKETAPT------TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 559

Query: 348 ASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSL 407
              P+  +   P P+  +         P  AP+  K P+  +    +P+      T    
Sbjct: 560 PEEPTPTTPEEPAPTTPKAAAPNTPKEP--APTTPKEPAPTTPKEPAPT------TPKET 611

Query: 408 SPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFE--VATCVSP 465
           +PTT       P  T    L    P     TTP     P     APTTT E    TC  P
Sbjct: 612 APTT-------PKGTAPTTLKEPAP-----TTP---KKPAPKELAPTTTKEPTSTTCDKP 656

Query: 466 -PMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLR--IPVSPPLPDPEDLKNLPSSV 522
            P +    +   P  PA       AP  P     TTL+   P +P  P P++L    +  
Sbjct: 657 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 716

Query: 523 LVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQST------ 576
                + K   T P   E AP +P +   TT K P   P     P  + S  ST      
Sbjct: 717 PTSTTSDKPAPTTPK--ETAPTTPKEPAPTTPKKPA--PTTPETPPPTTSEVSTPTTTKE 772

Query: 577 ---------SSSPEIPLSPEATLAKKSLGEP-LPIGKPASSMTSPLGVNSSASVIKTDSY 626
                     S+PE+   P     + S  EP +P  K  ++    +   +     + D  
Sbjct: 773 PTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLR 832

Query: 627 AGPD--SAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPF---LEGTV 681
             P+  +A P +     T T      E    + +  TT + TST T   +PF      T 
Sbjct: 833 TTPETTTAAPKMTKETATTT------EKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 886

Query: 682 SLAPKNHPVKEGTLTTLPLVPTASENCPV---APSPQNTCAPLATLVLAPEIPKSVPSPS 738
           +LAPK    K+ T+TT  ++    E       A + + T         AP+ P S   P 
Sbjct: 887 TLAPKVTTTKK-TITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPK 945

Query: 739 LPPAGTPPGT 748
             P    P T
Sbjct: 946 TMPRVRKPKT 955



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 70/280 (25%), Positives = 99/280 (35%), Gaps = 25/280 (8%)

Query: 2   PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
           P    E  P T +E P P       P +   +      +P PT P   +P   + P    
Sbjct: 549 PTTPEELAPTTPEE-PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 607

Query: 62  NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAP---EAPTFLPNLIGPPISPAALAL 118
            + +   +P   A T L+ P P +    A P   AP   + PT        P +P   A 
Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666

Query: 119 ASPM-IAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSA 177
            +P   APT   TP   AP      AP ++++ +   P              G   T S 
Sbjct: 667 TTPKEPAPT---TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 723

Query: 178 PIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTT 237
             AP+ PK      P E  P     P+P     T P    TP  +  +   S P TT   
Sbjct: 724 KPAPTTPKETAPTTPKEPAPTTPKKPAP-----TTP---ETPPPT--TSEVSTPTTTKEP 773

Query: 238 TLAIASPQVK------DTTISSVLISPQNPGSLSLKGPVS 271
           T    SP         + T  ++  SP+ PG  + K P +
Sbjct: 774 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 813



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 73/309 (23%), Positives = 116/309 (37%), Gaps = 47/309 (15%)

Query: 3   GEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAAN 62
           G A  T+       P+  A   + P ++    +    +P PT P   +P   + P     
Sbjct: 618 GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTP 677

Query: 63  QASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPM 122
           +     +P   A T L+ P P           T P+ P   P  + P  +    +  S  
Sbjct: 678 KEPAPTTPKGTAPTTLKEPAP-----------TTPKKPA--PKELAPTTTKGPTSTTSDK 724

Query: 123 IAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPS 182
            APT   TP  +AP      AP + +K +   P   T PP+ +         +S P    
Sbjct: 725 PAPT---TPKETAPTTPKEPAPTTPKKPAPTTPE--TPPPTTS--------EVSTPTTTK 771

Query: 183 EPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCV----TPMASIQSGVASLP------- 231
           EP T ++K P E  P     P+P  + ++     V    TP A+      +         
Sbjct: 772 EP-TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 830

Query: 232 -QTTPTTTLAIASPQVKDT------TISSVLISPQNPGSLSLKGPVSPPAALSLSTQSL- 283
            +TTP TT A A    K+T      T  S + +     + +     +P    +L T +L 
Sbjct: 831 LRTTPETTTA-APKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLA 889

Query: 284 PVVTSSQKT 292
           P VT+++KT
Sbjct: 890 PKVTTTKKT 898


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score =  286 bits (733), Expect = 1e-76
 Identities = 304/1047 (29%), Positives = 404/1047 (38%), Gaps = 178/1047 (17%)

Query: 711  APSPQNTCAPLATLVLAPEIPKSV-PSPSLPPA-----------GTPPGTKKVDGISHTS 758
            A +   T A  A  +L P  P S  P P + PA           G  P  ++  GI    
Sbjct: 10   AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG--G 67

Query: 759  ALAPVASSPKECPTEDSGASAT-------ASSKGTLTYLADSPSPLGVSVSPQTKRPPTK 811
            A  P  S+P+  PT  +G S+        AS +G     A + SP  VS SP      T+
Sbjct: 68   ATIP-ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS-SPGRASGTTR 125

Query: 812  KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTP--PSP------KG 863
             G  G      +    V+  +A+  P+ S    G++     T  PTP  PSP      + 
Sbjct: 126  PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRD---TSGPTPGTPSPAMARRSRA 182

Query: 864  APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPA------------- 910
            A T   +   +P     PP E P  SV +         +PA ++ P+             
Sbjct: 183  AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242

Query: 911  ------LSMTSSSPKKARATPAPKGIPASPSPKG--APTPPAATPP----SPKGGPATPS 958
                  LS  + S   AR TP     P+ P PKG  A  PP  TPP    +P  GP + S
Sbjct: 243  SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302

Query: 959  PKWAPTPPA--ATPPSPKGGPATPSPKGAP-TPPAATP-----PSPKGGPATPS-PKGAP 1009
            P   P+P    A P  P    ATP P   P +PP ATP     PSP   P+  + P    
Sbjct: 303  PLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA 362

Query: 1010 TPPAVTPPSPKGSPAATP----------FPKGASTPPAATPPSPKG-SPAATPLPKGAPT 1058
            TPP+  PPS    P   P           P   ++P    PPSP   S        G+PT
Sbjct: 363  TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPT 422

Query: 1059 TPAATLPSPKGGPATPSLKGAPTPPAATPP------SPKGGPATPSPKGAPMPPAATPPS 1112
              A           T +   +P+ PA+TPP      +P   PA+P P    + PA +P S
Sbjct: 423  LQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASP-PLQTSLSPAVSPLS 481

Query: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPP--------PKGAPTTPAA--TPPSPKGG 1162
                L   P +   +  + +P +P   L  PP        P    T PA+  TPP     
Sbjct: 482  SP--LTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP 539

Query: 1163 LATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP-SPKGGLATPSPKGAPTTP 1221
               PPP    + P  TP         P P  AP +P  TPP      +ATP P+  P   
Sbjct: 540  SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA 599

Query: 1222 A----ATPPSPKGGLATPSPKGAP---TTPAATPPSPKGGPATPPPKGAPTPPAATPPSL 1274
            +      P  P   LATP P+  P     P   PPSP   PA+PP     TP    P +L
Sbjct: 600  SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP---PASPPLSPLATPSPQAPNAL 656

Query: 1275 KGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPT 1334
               L   P    P+P V  P SP   P  SP   + TPP+  PP    S   PP +  P+
Sbjct: 657  AVHLLQAPFSPPPSPPVQAPFSPPASPPVSP---SATPPSQAPP----SLAAPPLQVPPS 709

Query: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPA 1394
            PPA  P SP  TP   A  P +      P  +  P+PPA+ P     P+ TPP P+  P 
Sbjct: 710  PPASPPMSPSATPPPQAPPPLA-----APPLQVPPSPPASPPM---SPSATPP-PRVPPL 760

Query: 1395 IPSP--KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAP 1452
            + +P  +  P+ PA +P+SP   P        A  P +   +PPA  P     +P+ S P
Sbjct: 761  LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 820

Query: 1453 KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP---MGAPTLPAVI 1509
                ATP  +  P L A   P  + PP+P    T  +P++ P TP P   +  P L   +
Sbjct: 821  MSPLATPPPQAPPVLAA---PLLQVPPSPPASPTLQAPRR-PPTPGPDTSVSGPRLTLAL 876

Query: 1510 PSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569
               P   P  PS           L    + AT  P+E                     + 
Sbjct: 877  APGP---PPPPSRSPSSTLSGPDLAGHSSSATSTPEEL--------------------RG 913

Query: 1570 APATPSSKEASSPP------AVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS 1623
              + P    A+SPP      A  P+ +   P+P     P A         P PPA  P S
Sbjct: 914  YDSGPEGGAAASPPPDAELAACHPAAWSRGPAP-----PLAFRGAPGAPLPWPPATGPGS 968

Query: 1624 PE--------KGP--ATPAPKGTPTSP 1640
             +        +GP  ATPAP      P
Sbjct: 969  ADGLCTIYETEGPESATPAPGALDPGP 995



 Score =  264 bits (674), Expect = 8e-70
 Identities = 297/1022 (29%), Positives = 399/1022 (39%), Gaps = 149/1022 (14%)

Query: 465  PPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTL---RIPVSPPLPDPEDLKNLPSS 521
            PP S  P   + P +   L  A    ++P  + A  +    IP S P   P       S 
Sbjct: 29   PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSR 88

Query: 522  VLV----------KFPTQKDLQTVPASLEGA------PFSPAQAGLTTKKDPTVLP-LVQ 564
                         + P  K+    P S  G       P    Q GL    + TV      
Sbjct: 89   NPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT 148

Query: 565  AAPKNSPSFQST--SSSPEIPLSPEATLAKKS--------LGEPLPIGKPASSMTSPLGV 614
             APK S         +S   P +P   +A++S        L  P P  +P      P   
Sbjct: 149  EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 208

Query: 615  NSSASVIKTDSYAG-----PDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTY 669
             SSAS   T   +      P + G L + +  + + +A PL S  PA   P+ A+GT   
Sbjct: 209  VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS--PARSGPS-ARGTPRA 265

Query: 670  TTTAS-PFLEGTVSLAPKN--HPVKE-----GTLTTLPLV---PTASENCPVAPSPQNTC 718
                S P  +G  +L P     P K+     G L++ PL    P+ ++  PV P P N  
Sbjct: 266  PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPP-PDNAA 324

Query: 719  APLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGAS 778
             PL    L P  P + P P  PP+ + P + +       +  +P A+ P + P   S  +
Sbjct: 325  TPLPA-TLPPSPPLATPLPLAPPSPSAPPSLQ-------TLPSPPATPPSQAPP--SMTT 374

Query: 779  ATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPE 838
                +  +L  +     P  ++ SP  + PP+    +       +L SP      SFL  
Sbjct: 375  PPMQAPPSLQTIPPIQVPHSLT-SPSLQAPPSPLALSSLQATT-SLGSPTLQATHSFLTM 432

Query: 839  NSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNL-PFPK 897
            +    Q S  SP+   S TPP       P ++    P   +L P  +P  S + + P   
Sbjct: 433  SPRQTQASLTSPSRPAS-TPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQA 491

Query: 898  EGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATP 957
                     QAP LS     P + +++ AP  +   P+     TPP    PS    P   
Sbjct: 492  LSSLASHSPQAP-LSSLIMPPLETQSSLAPPSLQTPPA--SLTTPPLENLPSLAPPPLQT 548

Query: 958  SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAP---TPPAV 1014
            +     TP   TPP P   P    P    TPP  TP S     ATP P+  P   +PP  
Sbjct: 549  ASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI----ATPPPQAPPALASPPLQ 604

Query: 1015 TPPSPKGSPAATPFPKGA---STPPAATPPSPKGSPAATPLPKGAPTTPAAT----LPSP 1067
              PSP  SP ATP P+     + PP   PPSP  SP  +PL   +P  P A     L +P
Sbjct: 605  GLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 664

Query: 1068 KGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPT 1127
               P +P ++   +PPA+ P SP   P + +P     PP   PPSP    A+PP   + T
Sbjct: 665  FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP---ASPPMSPSAT 721

Query: 1128 TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAP---TTPAATPPSPKG 1184
             P   PP     LA PP +  P+ PA+ P SP    ATPPP+  P     P   PPSP  
Sbjct: 722  PPPQAPPP----LAAPPLQVPPSPPASPPMSPS---ATPPPRVPPLLAAPPLQVPPSPPA 774

Query: 1185 GLA-TPSPKGAPTTPAATPPSPKGGLATPS---PKGAPTTPAAT-PPSPKGGLATPSPKG 1239
             L  +P  K  P  P A    P   L +P    P  AP +P+A+ P SP   LATP P+ 
Sbjct: 775  SLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP---LATPPPQA 831

Query: 1240 APTTPAA---TPPSPKGGPATPPPKGAPTP----------------PAATPP---SLKGG 1277
             P   A     PPSP   P    P+  PTP                P   PP   S    
Sbjct: 832  PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 891

Query: 1278 LATPPHKGAPNPAVVTPPS-------PKGGPATSPPKGAPTP---PAATPPSP------K 1321
            L+ P   G  + A  TP         P+GG A SPP  A      PAA    P      +
Sbjct: 892  LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR 951

Query: 1322 GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGG 1381
            G+PG P     P PPA  P S  G  T+  T      GP + +   G   P  +P   GG
Sbjct: 952  GAPGAP----LPWPPATGPGSADGLCTIYETE-----GPESATPAPGALDPGPSPGTSGG 1002

Query: 1382 PA 1383
             A
Sbjct: 1003 KA 1004



 Score =  261 bits (668), Expect = 4e-69
 Identities = 285/980 (29%), Positives = 376/980 (38%), Gaps = 143/980 (14%)

Query: 944  AATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP 1003
            A TP +   G  TP P  +P PP   P +P       +       P A      GG   P
Sbjct: 14   ARTPAARAPGLLTPRPPGSPRPPP--PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71

Query: 1004 --SPKGAPTPPAVTPP-SPKGSPAATPFPKGASTPPAA-TPPSPKGSPAAT-----PLPK 1054
              +P+  PT  A T   +P   P A+   +G   PPA  T P P  SP        P P 
Sbjct: 72   ESAPRAGPTRSAGTSSRNPASRPPASG--RGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129

Query: 1055 GAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPK 1114
            G      +   +   G AT + K +     A   +    P TPSP  A    AA     +
Sbjct: 130  GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA---GTE 186

Query: 1115 GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG--AP 1172
             GL  P     P  P   P       A+      P+  A   PS  GGL  P  +   + 
Sbjct: 187  VGLPRPAPSARPRPPTEGPRKSVSS-ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245

Query: 1173 TTPAATPPSPKGGLATPSPKGAPTTPA-ATPPSPKGGLATPSPKGAPTTPAATP---PSP 1228
             TP ++P       + PS +G P  PA  + P PKG  A   P+  P    A P   P  
Sbjct: 246  ATPLSSPAR-----SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300

Query: 1229 KGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAP-TPPAATPPSLKGGLATPPHKGAP 1287
               LATPSP G      A P  P    ATP P   P +PP ATP  L      PP   AP
Sbjct: 301  SSPLATPSPSGTK----ARPVPPPDNAATPLPATLPPSPPLATPLPL-----APPSPSAP 351

Query: 1288 NPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP 1347
             P++ T PSP   P +  P    TPP   PPS +  P    P    +P    PPSP    
Sbjct: 352  -PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALS 410

Query: 1348 TLPATTPSSKGGPTTPSSKE----GPTPPAATPSHKGGPAMTPP------SPKRGPAIPS 1397
            +L ATT  S G PT  ++       P    A+ +    PA TPP      +P   PA P 
Sbjct: 411  SLQATT--SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASP- 467

Query: 1398 PKGDPTSPAVIPLS------PKKAPATPVTREGAATPS---------KGDLTPPAVT--P 1440
            P     SPAV PLS      P +A ++  +    A  S         +  L PP++   P
Sbjct: 468  PLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP 527

Query: 1441 VSLKKAPATSAPKGGPATPSSKGDP-TLPAV-TPPSP-----KEPPAPKQVATSSSPKKA 1493
             SL   P  + P   P    +   P T P + TPP P     + PP+P       +P   
Sbjct: 528  ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI 587

Query: 1494 PATPAPMGAPTLPAV----IPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALI 1549
             ATP P   P L +     +PS P    ATP  +  P      L +  +P    P   L 
Sbjct: 588  -ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLA 646

Query: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA---VTPSTYKGAPSPKELLIPPAVT 1606
             P+   P+      +  P   P +P  +   SPPA   V+PS    + +P  L  PP   
Sbjct: 647  TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 706

Query: 1607 SPSPKEAP------TPPAVTPPSPEKGPATPAPKGTPTSPPVTPSS-------------- 1646
             PSP  +P      TPP   PP P   P    P   P SPP++PS+              
Sbjct: 707  PPSPPASPPMSPSATPPPQAPP-PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765

Query: 1647 LKDSPTSPASVTCK-MGATVPQASKGL-------------------PAKKGPTALKEVLV 1686
            L+  P+ PAS+    +    PQA   L                   P     +     L 
Sbjct: 766  LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 825

Query: 1687 APAPESTPIITAPTRKGPQTKKSSAT--SPPICPDPSAKNGSKGPLST--VAPAPLLPVQ 1742
             P P++ P++ AP  + P +  +S T  +P   P P       GP  T  +AP P  P  
Sbjct: 826  TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 885

Query: 1743 KDSSKTAKGKD-ASHSPKGPLAPPESKA--STPLTAAAFEKVLPKPES-------ASVSA 1792
            +  S T  G D A HS      P E +   S P   AA     P P++       A+ S 
Sbjct: 886  RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA---ASPPPDAELAACHPAAWSR 942

Query: 1793 APSPPVSLPLAP-SPVPTLP 1811
             P+PP++   AP +P+P  P
Sbjct: 943  GPAPPLAFRGAPGAPLPWPP 962



 Score =  251 bits (642), Expect = 4e-66
 Identities = 295/1034 (28%), Positives = 386/1034 (37%), Gaps = 199/1034 (19%)

Query: 907  QAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPA---------------------- 944
            +A A + T ++      TP P G P  P P    TP A                      
Sbjct: 9    KAGAAARTPAARAPGLLTPRPPGSPRPPPP---VTPAALRVLGAAGAVGRKPLAERAGGI 65

Query: 945  --ATPP--SPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAA-------TP 993
              AT P  +P+ GP   +   +  P +  P S +G  A P+   +P P ++       T 
Sbjct: 66   GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125

Query: 994  PSPKG--------------GPATPSPK------------GAPTPPAVTPPSPKGSPAA-- 1025
            P P G              G AT +PK              PTP   +P   + S AA  
Sbjct: 126  PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 185

Query: 1026 ---TPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG---PATPSLKGA 1079
                P P  ++ P   T    K   +A+      P+  A   PS  GG   PA+ SL  +
Sbjct: 186  EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245

Query: 1080 PTP---PAATPPSPKG------GPATPSPKG--APMPPAATPPSPKGGLATPPHKGAPTT 1128
             TP   PA + PS +G       P+ P PKG  A  PP  TPP      A  P     ++
Sbjct: 246  ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP---LSSS 302

Query: 1129 PAATPPSPKGGLA--TPPPKGAPT-TPAATPPSPKGGLATPPPKGAPTTPAATP-----P 1180
            P AT PSP G  A   PPP  A T  PA  PPSP   LATP P  AP +P+A P     P
Sbjct: 303  PLAT-PSPSGTKARPVPPPDNAATPLPATLPPSPP--LATPLPL-APPSPSAPPSLQTLP 358

Query: 1181 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP--KGGLATPSPK 1238
            SP     + +P    T P   PPS +       P    +     PPSP     L   +  
Sbjct: 359  SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418

Query: 1239 GAPTTPA----------------ATPPSPKGGPATPPPKGAPTPPAATPP---------- 1272
            G+PT  A                 +P  P   P   PP  AP    A+PP          
Sbjct: 419  GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVS 478

Query: 1273 SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP--------PKGAPTPPAA--TPPSPKG 1322
             L   L   P +   + A  +P +P       P        P    TPPA+  TPP    
Sbjct: 479  PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL 538

Query: 1323 SPGTPPP---KGAP--TPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPS 1377
                PPP     AP  TP   TPP P   P     +P +   P TPSS   P PP A P+
Sbjct: 539  PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATP-PPQAPPA 597

Query: 1378 HKGGPAMTPPSPKRGP------------AIPSPKGDPTSPAVIPLSPKKAPATPVTREGA 1425
                P    PSP   P            A+P  +  P+ PA  PLSP   P+       A
Sbjct: 598  LASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA 657

Query: 1426 ATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVA 1485
                +   +PP   PV    +P  S P    ATP S+  P+L A     P  PPA   ++
Sbjct: 658  VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 717

Query: 1486 TSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPK 1545
             S++P   P  P P+ AP  P  +P SP   PA+P     P++P+AT    + P  LA  
Sbjct: 718  PSATP--PPQAPPPLAAP--PLQVPPSP---PASP-----PMSPSAT-PPPRVPPLLAAP 764

Query: 1546 EALIPPAMTVPSPKKTPAIPTPKEAP--ATPSSKEASSPPAVTPSTYKGAPSPKELLIPP 1603
               +PP+     P    A P P+  P  ATP  +   SPPA  P     +PS    + P 
Sbjct: 765  PLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 824

Query: 1604 AVTSP-SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMG 1662
            A   P +P     P    PPSP   P   AP+  PT  P       D+  S   +T  + 
Sbjct: 825  ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP-------DTSVSGPRLTLALA 877

Query: 1663 ATVPQASKGLPAK--KGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPP----- 1715
               P      P+    GP        + +  STP        GP+    +A SPP     
Sbjct: 878  PGPPPPPSRSPSSTLSGPDLAGH---SSSATSTPEELRGYDSGPE--GGAAASPPPDAEL 932

Query: 1716 -ICPDPSAKNGSKGPL----STVAPAPLLPVQKDSSK-------TAKGKDASHSPKGPLA 1763
              C   +   G   PL    +  AP P  P     S          +G +++    G L 
Sbjct: 933  AACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALD 992

Query: 1764 PPESKASTPLTAAA 1777
            P  S  ++   AAA
Sbjct: 993  PGPSPGTSGGKAAA 1006



 Score =  241 bits (616), Expect = 4e-63
 Identities = 303/1077 (28%), Positives = 392/1077 (36%), Gaps = 191/1077 (17%)

Query: 1032 ASTPPAATPPSPKGSPAATPLPKGA-----PTTPAATLPSPKGGPA--TPSLKGAPTPPA 1084
            A    AA  P+ +     TP P G+     P TPAA       G     P  + A     
Sbjct: 8    AKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67

Query: 1085 ATPP--SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP--------P 1134
            AT P  +P+ GP T S   +   PA+ PP+   G   PP K     P ++P        P
Sbjct: 68   ATIPESAPRAGP-TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126

Query: 1135 SPKG--------------GLATPPPKGAPTTPAA-------TP--PSP-----------K 1160
             P G              G AT  PK +  +  A       TP  PSP           +
Sbjct: 127  GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186

Query: 1161 GGLATPPPKGAPTTPAATP----------------------PSPKGGLATPSPK--GAPT 1196
             GL  P P   P  P   P                      PS  GGL  P+ +   +  
Sbjct: 187  VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 246

Query: 1197 TPAATPPSPKGGLATPSPKGAPTTPA-ATPPSPKGGLATPSPKGAPTTPAATP------- 1248
            TP ++P       + PS +G P  PA  + P PKG  A   P+  P    A P       
Sbjct: 247  TPLSSP-----ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301

Query: 1249 -----PSPKGGPA--TPPPKGAPTP-PAATPPSLKGGLAT-----PPHKGAPNPAVVTPP 1295
                 PSP G  A   PPP  A TP PA  PPS    LAT     PP   AP P++ T P
Sbjct: 302  SPLATPSPSGTKARPVPPPDNAATPLPATLPPS--PPLATPLPLAPPSPSAP-PSLQTLP 358

Query: 1296 SPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355
            SP   P +  P    TPP   PPS +  P    P    +P    PPSP    +L ATT  
Sbjct: 359  SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATT-- 416

Query: 1356 SKGGPTTPSSKE----GPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLS 1411
            S G PT  ++       P    A+ +    PA TPP     P + +P   P SP   PL 
Sbjct: 417  SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD---SPPLQAPLSLPASP---PLQ 470

Query: 1412 PKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471
               +P        A +P    LT   +  +S   + +  AP      P  +   T  ++ 
Sbjct: 471  TSLSP--------AVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLE---TQSSLA 519

Query: 1472 PPSPKEPPA-----PKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDP 1526
            PPS + PPA     P +   S +P       AP+  P L      +P  + A PS    P
Sbjct: 520  PPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP 579

Query: 1527 IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAP---ATPSSKEASSPP 1583
              P  T  S  TP   AP     PP   +PSP  +P    P +AP   A P  +   SPP
Sbjct: 580  --PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPP 637

Query: 1584 AVTPSTYKGAPSPK-------ELLIPPAVTSPSPK-EAP-TPPAVTPPSPEKGPATPAPK 1634
            A  P +    PSP+        LL  P    PSP  +AP +PPA  P SP   P + AP 
Sbjct: 638  ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 697

Query: 1635 GTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEV--LVAPAPES 1692
                 P   P S   SP    S T    A  P A+  L     P A   +     P P  
Sbjct: 698  SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757

Query: 1693 TPIITAPTRKGPQTKKSSATSPPIC-PDPSAKNGSKGPLSTVAPAP--LLPVQKDSSKTA 1749
             P++ AP  + P +  +S    P+  P P A      P     P+P    P Q   S +A
Sbjct: 758  PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 817

Query: 1750 KGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAP-------------SP 1796
                    P  PLA P  +A  P+ AA   +V P P ++    AP              P
Sbjct: 818  S------LPMSPLATPPPQA-PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 870

Query: 1797 PVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPAD-------EDELLPLIPPEPI 1849
             ++L LAP P P          S P L   S S    P +        +      PP   
Sbjct: 871  RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA 930

Query: 1850 SGGVPFQSVLVNMPTPKSA-----GIPVPTPSAKQPVTKNNKGSGTESDSDES-VPELEE 1903
                   +     P P  A     G P+P P A  P + +   +  E++  ES  P    
Sbjct: 931  ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA 990

Query: 1904 QDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIR 1960
             D   +       AAA             SRS K+AR     LG  Q + V  +  R
Sbjct: 991  LDPGPSPGTSGGKAAAG------AGAGASSRSPKQARLGELPLGALQASVVQHLLSR 1041



 Score =  234 bits (598), Expect = 5e-61
 Identities = 309/1114 (27%), Positives = 415/1114 (37%), Gaps = 147/1114 (13%)

Query: 180  APSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTL 239
            A +  +T   + P  + P P G+P PP          VTP A    G A      P   L
Sbjct: 10   AGAAARTPAARAPGLLTPRPPGSPRPP--------PPVTPAALRVLGAAGAVGRKP---L 58

Query: 240  AIASPQVKDTTI--SSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNT 297
            A  +  +   TI  S+    P      S + P S P A                  G   
Sbjct: 59   AERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPA---------------SGRGERA 103

Query: 298  PPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVI 357
            PP    S G   +P   S       LGQ G    ++ TV       +   A+   +RS +
Sbjct: 104  PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV-------ARGKATEAPKRSAL 156

Query: 358  PPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKS 417
                 R+   P      P +A       + +     +PS      T     P  S+   S
Sbjct: 157  SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE---GPRKSVSSAS 213

Query: 418  SPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEP 477
              + T   P   + P +  G     +  P + + + +     AT +S P  SGP +   P
Sbjct: 214  EHSTTEPSPAARRRPSAGGG-----LQRPASRSLSSS-----ATPLSSPARSGPSARGTP 263

Query: 478  TSPAALVMAPVAPKEPSTQVATTLRIP-VSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVP 536
             +PA        P +P  +    LR P V+PP  D        SS  +  P+    +  P
Sbjct: 264  RAPA-------HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARP 316

Query: 537  ASLEGAPFSPAQAGLTTKKD-PTVLPLVQAAPKNSPSFQSTSSSPEIPLS---PEATL-- 590
                    +P  A L       T LPL   +P   PS Q+  S P  P S   P  T   
Sbjct: 317  VPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP 376

Query: 591  --AKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAG-PLLKSS----LITP 643
              A  SL    PI  P  S+TSP  + +  S +   S     S G P L+++     ++P
Sbjct: 377  MQAPPSLQTIPPIQVP-HSLTSP-SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434

Query: 644  TVAAFPLES-ADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVP 702
                  L S + PA   P +    +  +  ASP L+   SL+P   P+     + L + P
Sbjct: 435  RQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQ--TSLSPAVSPLS----SPLTIHP 488

Query: 703  TASENCPVAPSPQNTCAPLATLVLAP-EIPKSVPSPSLPPAGTPPGTKKVDGISHTSALA 761
              + +   + SPQ   APL++L++ P E   S+  PSL    TPP          +    
Sbjct: 489  LQALSSLASHSPQ---APLSSLIMPPLETQSSLAPPSLQ---TPPA---------SLTTP 533

Query: 762  PVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPI 821
            P+ + P   P     ASA  ++    T    +P PL    SP T  PP    S     P 
Sbjct: 534  PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593

Query: 822  GNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLP 881
               +    P++   LP   LS   +    A      PP  +  P+P A  PLSP  +  P
Sbjct: 594  APPALASPPLQG--LPSPPLSPLATPPPQAPPXLALPPL-QAPPSPPASPPLSP--LATP 648

Query: 882  PKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIP--ASPSPKGA 939
              + P    V+L      P    P QAP  S  +S P    ATP  +  P  A+P  +  
Sbjct: 649  SPQAPNALAVHLLQAPFSPPPSPPVQAP-FSPPASPPVSPSATPPSQAPPSLAAPPLQVP 707

Query: 940  PTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGP-----ATPSPK----------- 983
            P+PPA+ P SP   P   +P     PP   PPSP   P     ATP P+           
Sbjct: 708  PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQ 767

Query: 984  GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS-PAATPFPKGASTPPAATPPS 1042
              P+PPA+ P SP   P   +P    TPP    PSP  S P   PF   AS P       
Sbjct: 768  VPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM------ 821

Query: 1043 PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGA 1102
               SP ATP P+  P   A  L  P   PA+P+L+    PP   P +   GP       A
Sbjct: 822  ---SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL-A 877

Query: 1103 PMPPAATPPSPKGGLATPPHKGAPTTPAATP-------PSPKGGLATPPPKGAPTT---P 1152
            P PP     SP   L+ P   G  ++  +TP         P+GG A  PP  A      P
Sbjct: 878  PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHP 937

Query: 1153 AATPPSPKGGLATPPPKGAPTT-PAATPPSPKGGLA----TPSPKGAPTTPAATPPSPKG 1207
            AA    P   LA     GAP   P AT P    GL     T  P+ A   P A  P P  
Sbjct: 938  AAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 997

Query: 1208 GLATPSPKGAPTTPA-ATPPSPKGGLATPSPKGA 1240
            G  T   K A    A A+  SPK       P GA
Sbjct: 998  G--TSGGKAAAGAGAGASSRSPKQARLGELPLGA 1029



 Score =  146 bits (369), Expect = 2e-34
 Identities = 246/974 (25%), Positives = 353/974 (36%), Gaps = 167/974 (17%)

Query: 27   PMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSS 86
            P  SALS  A     GPT   P     ++   +      P P+PS     P E P    S
Sbjct: 151  PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS 210

Query: 87   S----GTALPLGTAPEAPTFLPNLIGP---PISPAALALASP-MIAPTLKGTPSSSA--- 135
            S     T  P   A   P+    L  P    +S +A  L+SP    P+ +GTP + A   
Sbjct: 211  SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 270

Query: 136  ---PLALVALAPHSV---QKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLN 189
               P  L AL P  V   +K +A     L+S P    + SG   T + P+ P  P     
Sbjct: 271  QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSG---TKARPVPP--PDNAAT 325

Query: 190  KVPSEVVPNP---------KGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLA 240
             +P+ + P+P           +PS P  + T+P    TP +     + + P   P +   
Sbjct: 326  PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQT 385

Query: 241  IASPQVKDTTISSVLISPQNPGSL-SLKGPVSPPAALSLSTQSLPVVTSSQKTA---GPN 296
            I   QV  +  S  L +P +P +L SL+   S  +    +T S   ++  Q  A    P+
Sbjct: 386  IPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPS 445

Query: 297  TPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDP-TVKTISVDHS--STGASYPSQ 353
             P   P       APL   +   +Q       S LS P T+  +    S  S     P  
Sbjct: 446  RPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS 505

Query: 354  RSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSL 413
              ++PPL +++ + P          PS+   P   +S+T  P  +L      SL+P   L
Sbjct: 506  SLIMPPLETQSSLAP----------PSLQTPP---ASLTTPPLENLP-----SLAP-PPL 546

Query: 414  ILKSSPNATYHY-------PLVAQMPVSSVGT----TPLVVTNPCTIAAAPTTTFEVATC 462
               S+P  T H        P   Q P S + T    TP  +  P   A     +  +   
Sbjct: 547  QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGL 606

Query: 463  VSPPMSSGPISNIEPTSPAALVMAPV------------------APKEPSTQVATTLRIP 504
             SPP+S  P++   P +P  L + P+                  +P+ P+      L+ P
Sbjct: 607  PSPPLS--PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 664

Query: 505  VSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFS-PAQAGLTTKKDPTVLPLV 563
             SPP   P      P +     P+       P SL   P   P     +    P+  P  
Sbjct: 665  FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 724

Query: 564  QAAPK-NSPSFQSTSSSP-EIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVI 621
            QA P   +P  Q   S P   P+SP AT   +    PL    P     SP      AS+ 
Sbjct: 725  QAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV--PPLLAAPPLQVPPSP-----PASLP 777

Query: 622  KTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTV 681
             +     P  A P    +L TP + A P   A   G AP +   +   +  A+P      
Sbjct: 778  MSPLAKPPPQAPP----ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP------ 827

Query: 682  SLAPKNHPVKEGTLTTLPLVPTASENC-----PVAPSPQNTCA-PLATLVLAPEIPKSVP 735
               P+  PV    L  +P  P AS        P  P P  + + P  TL LAP  P   P
Sbjct: 828  --PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP---P 882

Query: 736  SPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPS 795
             PS  P+ T  G    D   H+S+     S+P+E    DSG    A++            
Sbjct: 883  PPSRSPSSTLSGP---DLAGHSSS---ATSTPEELRGYDSGPEGGAAAS----------- 925

Query: 796  PLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHS 855
                        PP       PD  +    +   P   S  P   L+F+G+  +P     
Sbjct: 926  ------------PP-------PDAEL----AACHPAAWSRGPAPPLAFRGAPGAPL---- 958

Query: 856  PTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS 915
            P PP+          T    +G   P   TP P  ++ P P  G +            +S
Sbjct: 959  PWPPATGPGSADGLCTIYETEG---PESATPAPGALD-PGPSPGTSGGKAAAGAGAGASS 1014

Query: 916  SSPKKARATPAPKG 929
             SPK+AR    P G
Sbjct: 1015 RSPKQARLGELPLG 1028



 Score =  137 bits (345), Expect = 1e-31
 Identities = 200/768 (26%), Positives = 270/768 (35%), Gaps = 191/768 (24%)

Query: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPS------------------------ 1319
            K     A  TP +   G  T  P G+P PP    P+                        
Sbjct: 7    KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66

Query: 1320 ----PKGSPGTPPPKGAPTP---PAVTPPS---------PKGTPTLPATTPSSKGGPTTP 1363
                P+ +P   P + A T    PA  PP+          K T   P ++P    G T P
Sbjct: 67   GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126

Query: 1364 ----------SSKEGPTPPAATPSHK------------GGPAMTPPSP---KRGPAIPSP 1398
                      S++E      AT + K             GP    PSP   +R  A  + 
Sbjct: 127  GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186

Query: 1399 KGDP-TSPAVIPLSPKKAPATPV---TREGAATPSK---------GDLTPPAVTPVSLKK 1445
             G P  +P+  P  P + P   V   +      PS          G L  PA   +S   
Sbjct: 187  VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 246

Query: 1446 APATSAPKGGPA---TPSSKGDPTLP------AVTPPS---PKEPPAPKQVATSSSP--- 1490
             P +S  + GP+   TP +   P+ P      A+ PP    P++  AP     SSSP   
Sbjct: 247  TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306

Query: 1491 ------KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAP 1544
                  K  P  P    A  LPA +P SP      P +   P AP +       PAT  P
Sbjct: 307  PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPAT-PP 365

Query: 1545 KEALIPPAMTVPSPKKTPAIPT--PKEAPATPSSKEASSPP------AVTPSTYKGAPSP 1596
             +A  PP+MT P  +  P++ T  P + P + +S    +PP      ++  +T  G+P+ 
Sbjct: 366  SQA--PPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL 423

Query: 1597 KE----LLIPPAVTSPSPKEAPTPPAVTPP------SPEKGPATPAPKGTPTSPPVTP-- 1644
            +     L + P  T  S   +P+ PA TPP      +P   PA+P P  T  SP V+P  
Sbjct: 424  QATHSFLTMSPRQTQAS-LTSPSRPASTPPDSPPLQAPLSLPASP-PLQTSLSPAVSPLS 481

Query: 1645 -----------------------SSLKDSP-------------TSPASVTCKMGATVPQ- 1667
                                   SSL   P             T PAS+T      +P  
Sbjct: 482  SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSL 541

Query: 1668 ASKGLPAKKGPTALKEVLVAPAPESTPIITAP---TRKGPQTKKSSATSPPICPDPSAKN 1724
            A   L     P     +   P P   P+   P   T   P+T  S AT PP  P   A  
Sbjct: 542  APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP 601

Query: 1725 GSKG----PLSTVAPAP--------LLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTP 1772
              +G    PLS +A  P        L P+Q   S  A        P  PLA P  +A   
Sbjct: 602  PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS------PPLSPLATPSPQAPNA 655

Query: 1773 LTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPL 1832
            L     +     P S  V A  SPP S P++PS     PP Q    + P L       P 
Sbjct: 656  LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS---ATPPSQ----APPSLAAPPLQVPP 708

Query: 1833 APADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQP 1880
            +P     + P   P P     P  +  + +P P     P  +PSA  P
Sbjct: 709  SPPASPPMSPSATPPP-QAPPPLAAPPLQVP-PSPPASPPMSPSATPP 754



 Score =  119 bits (298), Expect = 3e-26
 Identities = 171/664 (25%), Positives = 254/664 (38%), Gaps = 93/664 (14%)

Query: 10  PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPS 69
           P+  +  P P  + A  P+ + L  +  L  P P  PP  S  P    L +     P  +
Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA 368

Query: 70  PSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKG 129
           P ++ + P++ P     S   +P    P + T  P+L  PP SP AL   S + A T  G
Sbjct: 369 PPSMTTPPMQAP----PSLQTIPPIQVPHSLT-SPSLQAPP-SPLAL---SSLQATTSLG 419

Query: 130 TPSSSAPLALVALAPHSVQKSSAFP---------------PNLLTSPPSVAVAESGSVIT 174
           +P+  A  + + ++P   Q S   P               P  L + P +  + S +V  
Sbjct: 420 SPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSP 479

Query: 175 LSAPI--------------APSEPKTNLNKVPSEVVPN--PKGTPSPPCIVSTVPYHCVT 218
           LS+P+              +P  P ++L   P E   +  P    +PP  ++T P   + 
Sbjct: 480 LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP 539

Query: 219 PMASIQSGVASLPQTTP--TTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAAL 276
            +A      AS P TTP   T    A   ++          P+ P S++   P +PPA  
Sbjct: 540 SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA 599

Query: 277 SLSTQSLP-VVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPT 335
           S   Q LP    S   T  P  PP   ++L    AP    +   +  L    P A +   
Sbjct: 600 SPPLQGLPSPPLSPLATPPPQAPP--XLALPPLQAPPSPPASPPLSPLATPSPQAPNALA 657

Query: 336 VKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSP 395
           V  +    S              P PS     P +  A P V+PS         S+   P
Sbjct: 658 VHLLQAPFS--------------PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 703

Query: 396 SGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTT 455
              L V  S   SP        SP+AT   P  A  P+++    P +   P   A+ P +
Sbjct: 704 ---LQVPPSPPASP------PMSPSAT--PPPQAPPPLAA----PPLQVPPSPPASPPMS 748

Query: 456 TFEVATCVSPPMSSGPISNIEPTSPAALVMAPVA---PKEPSTQVATTLRIPVSPPLPDP 512
                    PP+ + P   + P+ PA+L M+P+A   P+ P       L+   SPP   P
Sbjct: 749 PSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFP 808

Query: 513 EDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPS 572
                 PS+ L   P    L T P     AP   A   L     P   P +Q AP+  P 
Sbjct: 809 GQAPFSPSASLPMSP----LATPPPQ---APPVLAAPLLQVPPSPPASPTLQ-APRRPP- 859

Query: 573 FQSTSSSPEIPLS-PEATLAKKSLGEPLPIGKPASSMTSP-LGVNSSASVIKTDSYAGPD 630
               +  P+  +S P  TLA      P P   P+S+++ P L  +SS++    +   G D
Sbjct: 860 ----TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD 915

Query: 631 SAGP 634
           S GP
Sbjct: 916 S-GP 918



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 119/461 (25%), Positives = 175/461 (37%), Gaps = 66/461 (14%)

Query: 5   ATETVPATEQ--ELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAAN 62
           A+ T P  E    L  P  +TA  P+++            P L  P  PAP  CPL A  
Sbjct: 528 ASLTTPPLENLPSLAPPPLQTASAPLTT------------PHLETPPCPAP--CPLQAPP 573

Query: 63  QASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPM 122
                P P T +S  +  P PQ+    A P      +P   P    PP +P  LAL    
Sbjct: 574 SPLTTPPPETPSS--IATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL---- 627

Query: 123 IAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLT---SPPSVAVAESGSVITLSAPI 179
             P L+  PS  A   L  LA  S Q  +A   +LL    SPP     ++      S P+
Sbjct: 628 --PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 685

Query: 180 A-----PSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGV-ASLPQT 233
           +     PS+   +L   P +V P+P  +P P    +T P     P+A+    V  S P +
Sbjct: 686 SPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQVPPSPPAS 744

Query: 234 TPTTTLAIASPQVKDTTISSVL-ISPQNPGSLSLK-----GPVSPPAALSLSTQSLPVVT 287
            P +  A   P+V     +  L + P  P SL +       P +PPA  +   Q+LP   
Sbjct: 745 PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804

Query: 288 SSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTV---KTISVDHS 344
           +S     P + P   + +     P  Q+       L Q  PS  + PT+   +       
Sbjct: 805 ASFPGQAPFS-PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 863

Query: 345 STGASYPSQRSVI----PPLPSRNEVVPATVAAFPVVA-------------PSVDKGPST 387
            T  S P     +    PP PSR+   P++  + P +A                D GP  
Sbjct: 864 DTSVSGPRLTLALAPGPPPPPSRS---PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 920

Query: 388 ISSITCSPSGSLNVA--TSFSLSPTTSLILKSSPNATYHYP 426
            ++ +  P   L      ++S  P   L  + +P A   +P
Sbjct: 921 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 961



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 58/193 (30%), Positives = 75/193 (38%), Gaps = 35/193 (18%)

Query: 1   MPGEATETVPATEQELPQPQAETAVL----------PMSSALSVTAALGQPGPTLPPPCS 50
           +P     + P +    P PQA   +           P S  +S +A    P P +PP  +
Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT---PPPRVPPLLA 762

Query: 51  PAPQQCP------LSAANQASPFPS-------------PSTIASTPLEVPFPQSSSGTAL 91
             P Q P      L  +  A P P              PS  AS P + PF  S+S    
Sbjct: 763 APPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 822

Query: 92  PLGT-APEAPTFL--PNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQ 148
           PL T  P+AP  L  P L  PP  PA+  L +P   PT     S S P   +ALAP    
Sbjct: 823 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 882

Query: 149 KSSAFPPNLLTSP 161
             S  P + L+ P
Sbjct: 883 PPSRSPSSTLSGP 895


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score =  270 bits (691), Expect = 8e-72
 Identities = 494/2157 (22%), Positives = 775/2157 (35%), Gaps = 328/2157 (15%)

Query: 6    TETVPATEQELPQPQAETA---VLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAAN 62
            T + P T +    P + T+    L  S  +S T        TL    +P   + P+  +N
Sbjct: 1256 TSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLT--TPVDTKGPVVTSN 1313

Query: 63   QASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLI------GPPISPAAL 116
            + S  P+P+   S P        +  T++P+ T   A + +  L         P++ +  
Sbjct: 1314 EVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTE 1373

Query: 117  ALASPMIA---------PTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVA 167
            A +SP  +         P+   TP +S P++   +        SA P +  TS P    A
Sbjct: 1374 ACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVD--TSTPGTTSA 1431

Query: 168  ESGSVITLSAPIA-----PSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMAS 222
            E+ S  T +  I+     PSE KT L  +P   V N     S    +ST P    +P+ +
Sbjct: 1432 EATSSPTTAEGISIPTSTPSEGKTPLKSIP---VSNTPVANSEASTLSTTPVDSNSPVVT 1488

Query: 223  IQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQS 282
              + V+S P     T++AI++P    T ++S+ +S     S  +    + PA  S     
Sbjct: 1489 -STAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTST---- 1543

Query: 283  LPVVTSSQKTAGPNTPPDFPISLGSHL---APLHQSSFGSVQLLGQTGPSALSDP----T 335
             PV T SQ ++ P T     +   ++     PL      ++ ++     +  + P    T
Sbjct: 1544 -PVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKT 1602

Query: 336  VKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSP 395
              T S + SS+  +  S  ++  P      +    V+  PV +P      ST+S+     
Sbjct: 1603 QVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEA----STLSTTPVDS 1658

Query: 396  SGSLNVATSFSLSPTTSLILKSSPNATY---HYPL---------VAQMPVSSVGTTPLVV 443
            +  +  +T  S SPT +    S P +TY     PL         VA   +S++ TTP+  
Sbjct: 1659 NSPVITSTEVSSSPTPAEGT-SMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDN 1717

Query: 444  TNPCTIA----AAPTTTFEVATCVSPP------MSSGPISNIEPTSPAALVMAPVAPKEP 493
            + P T +    ++PTT+   +   S P      ++S P+S     S  A  ++   P + 
Sbjct: 1718 STPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLS-ATPIDT 1776

Query: 494  STQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTT 553
            ST V T+     SP   +     ++P+S L +  T   L + P S      S A    TT
Sbjct: 1777 STPVTTSTEATSSPTTAEGT---SIPTSTLSEGMTP--LTSTPVSHTLVANSEASTLSTT 1831

Query: 554  KKDPTVLPLVQAAPKNSPS-FQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPL 612
              D     +   A  +SP+  + TS +   P   E + A  S+  P+     ASS T+ L
Sbjct: 1832 PVDSNSPVVTSTAVSSSPTPAEGTSIATSTP--SEGSTALTSI--PVSTTTVASSETNTL 1887

Query: 613  GVNSSASVIKTDSYAGPDSAG------------------PLLKSSLITPTVAAF------ 648
                + +     +YA   S+                   PL    + T TVA+       
Sbjct: 1888 STTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLS 1947

Query: 649  --------PLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPL 700
                    P+ +   A  +PTTA GTS  T   S       S+      V     +TL  
Sbjct: 1948 TTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLST 2007

Query: 701  VPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPP-AGTPPGTKKV-DGISHTS 758
             P  +   P   S + + +P  T      I  S PS    P AG P  T  V     +T 
Sbjct: 2008 TPVDTST-PATTSTEGSSSP--TTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTL 2064

Query: 759  ALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD 818
            +  PV S  +   + ++ +SATA             SPL  S+   T    + + S    
Sbjct: 2065 STTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLST 2124

Query: 819  TPIGNLSSPVSPVEASF--LPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPK 876
            TP+ + S  ++  E S   +P    S Q S  S   T   + P        SA++ LS  
Sbjct: 2125 TPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTT 2184

Query: 877  GVTLPPKETPTPSVVNLPFPKEGPA----TPAPKQAPALSM-------TSSSPKKARATP 925
             V      T +    + P   EG +    TP+    P  SM        +S      ATP
Sbjct: 2185 PVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATP 2244

Query: 926  APKGIPASPSPKGAPTPPAAT----PPSPKGGPATPSPKW---------APTPPAATPPS 972
                 P + S +   +P  A     P S      TP             +     +T P 
Sbjct: 2245 VDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPV 2304

Query: 973  PKGGPATPSPKGAPTPPAA------TPPSPKGG-PATPSPKGAP------TPPAVTPPSP 1019
                P T S + +  PP A      T  S +G  P T  P          T    T P+ 
Sbjct: 2305 DSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPAD 2364

Query: 1020 KGSPAATPFPKGASTPPA--ATPPSPKGSPAATPLPK---------GAPTTPAATLPSPK 1068
              +P  T    G+S   A   + P+   S  +TPL            +  +  +T P   
Sbjct: 2365 TSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDT 2424

Query: 1069 GGPATPSLKGAPTPPAATPPS-PKGGPATPSPKGAPMPPAATP--PSPKGGLATPPHKGA 1125
              P T S + + +P  A   S P   P+  +   A MP + TP   S  G L+T P   +
Sbjct: 2425 STPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTS 2484

Query: 1126 P----TTPAATPPSPKGGLATPPPKGAP-----------TTPAATPPSPKGGLATPP--- 1167
                 +T A++ P+    +  P    +            TTP A+P +    L+T P   
Sbjct: 2485 TPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEAST--LSTTPVDS 2542

Query: 1168 --PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1225
              P    T  +++  S +G     S     +TP  + P     LA+       TTP  T 
Sbjct: 2543 NSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTS 2602

Query: 1226 -PSPKGGLATPSPKGAPTT--PAATPPSPKGG-----PATPPPKGAPTPPAATPP----- 1272
             P       + SP  A  T  P +TP            +T P   +     +T P     
Sbjct: 2603 IPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRT 2662

Query: 1273 --SLKGGLATPPHKGAPNPAVVTPPSPKGGPAT-----------SPPKGAPTPPA--ATP 1317
              +   G ++ P     +    + P  +  P T           S      T P   +TP
Sbjct: 2663 LVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTP 2722

Query: 1318 PSPKGSPGTPPPKGAPTPPAVTPPSPKGTPT---LPATTPSSKGGPTTPSSKEGPTPPAA 1374
             +      + P     T   ++ PS   TP    L +T P +    +T S+    T    
Sbjct: 2723 VTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPV 2782

Query: 1375 TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKG--D 1432
            T S +   A + P+     ++P+     TS    PL+      TPV    A T S    D
Sbjct: 2783 TTSTE---ASSSPTTAEVTSMPTSTPSETST---PLTSMPVNHTPVASSEAGTLSTTPVD 2836

Query: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV----------------TPPSPK 1476
             + P  T      +P T+     P + +S+G   L ++                T P   
Sbjct: 2837 TSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDT 2896

Query: 1477 EPPAPKQVATSSSPKKAPATPAPMGAPT---------LPAVIPSSPKE---VPATPSSRR 1524
              P       SSSP  A  T  P+  P+         L + +P +  E   +  TP   R
Sbjct: 2897 SIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTR 2956

Query: 1525 DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTP-------AIPTPKEAPATPSSK 1577
             P+  +A   S  T A     E    P  T P  ++TP        +P      +T S  
Sbjct: 2957 TPVTTSAEASSSPTTA-----EGTSMPIST-PGERRTPLTSMSVSTMPVASSEASTLSRT 3010

Query: 1578 EASSPPAVTPSTY-KGAPSPKELLIPPAVTSPSPKEAPT---PPAVTPPS-PEKGPATPA 1632
             A +   VT ST    +P+  E    P +++PS    P    P + TP + PE    +  
Sbjct: 3011 PADTSTPVTTSTEASSSPTTAEGTGIP-ISTPSEGSTPLTSIPVSTTPVAIPEASTLSTT 3069

Query: 1633 PKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASK---GLPAKKGP---TALKEVLV 1686
            P  +  SP VT + +  SPT PA  T    +T  + S    G+P    P   +A+  +  
Sbjct: 3070 PVDS-NSPVVTSTEVSSSPT-PAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLST 3127

Query: 1687 APAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSS 1746
             P   STP+ T+       T     + P   P   +   +  P+ST+    L+   +DS+
Sbjct: 3128 TPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTM----LVVSSEDST 3183

Query: 1747 KTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSP 1806
             +A   D                STP+T +         E  S+  +       PL   P
Sbjct: 3184 LSATPVD---------------TSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVP 3228

Query: 1807 VPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPK 1866
            V   P            V  S +  L+    D   PL      S          + PT +
Sbjct: 3229 VSNTP------------VASSEASILSTTPVDSNTPLTTSTEASS---------SPPTAE 3267

Query: 1867 SAGIPVPTPS-AKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEI 1922
               +P  TPS    P+T     + T + S+ S       D++   T  +Q +++  I
Sbjct: 3268 GTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPI 3324



 Score =  266 bits (679), Expect = 2e-70
 Identities = 483/2121 (22%), Positives = 788/2121 (37%), Gaps = 277/2121 (13%)

Query: 5    ATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQA 64
            +T    +TE        E   +P+S+    +  L     ++ P  SP       +  +  
Sbjct: 775  STHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSN 834

Query: 65   SPFPSPSTIASTP-----LEVPFPQSSSG----TALPLGTAPEAPTFLPNLIGPPISPAA 115
            SP  + + ++S+P       +P    S G    T++P+ T   A + +  L   P+  + 
Sbjct: 835  SPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTST 894

Query: 116  LALAS---------------PMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTS 160
                S               P   P    TP +S P +   +     +  SA P +  T 
Sbjct: 895  PVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTP 954

Query: 161  PPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPM 220
              +   A S         I  S P      + S  V +     S    +ST P    TP+
Sbjct: 955  VTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPL 1014

Query: 221  ASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLST 280
             +  +  +S P T   T++  ++P    T ++ + +S     S       + PA  S   
Sbjct: 1015 TT-STEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPV 1073

Query: 281  QSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTIS 340
             +    +SS  TA   + P    S GS   PL      +  ++     +  + P   +I 
Sbjct: 1074 TTYSQASSSSTTADGTSMPTSTYSEGS--TPLTSVPVSTRLVVSSEASTLSTTPVDTSIP 1131

Query: 341  VDHSSTGASYP--SQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGS 398
            V  S+  +S P  ++ + IP  P      P  +A+ PV    V    +   S T   S +
Sbjct: 1132 VTTSTEASSSPTTAEGTSIPTSPPSEGTTP--LASMPVSTTLVVSSEANTLSTTPVDSKT 1189

Query: 399  LNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSS--VGTTPLVVTNPCTIAAAPTTT 456
                ++ + SP  +  + S P +T   P     P++S  V  TP+  +   T++ +P  T
Sbjct: 1190 QVATSTEASSPPPTAEVTSMPTST---PGERSTPLTSMPVRHTPVASSEASTLSTSPVDT 1246

Query: 457  FEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPL---PDPE 513
                   S P+++   ++  PT+     +      E ST + +   IPVS  L   P+  
Sbjct: 1247 -------STPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTS---IPVSTTLVTSPEAS 1296

Query: 514  DLKNLPSSVLVKFPTQKDLQTVPASLEGA--PFSPAQAGLTTKKD-PTVLPLVQAAPKNS 570
             L   P        T  ++ + P   EG   P S    G T     P    LV ++  + 
Sbjct: 1297 TLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISI 1356

Query: 571  PSFQSTSSSPEIPLSPEA-TLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGP 629
             S     +S  +  S EA +    S G  +P   P+   T    +              P
Sbjct: 1357 LSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSI--------------P 1402

Query: 630  DSAGPLLKSSLITPTVAAFPLESADP------AGVAPTTAKGTSTYTTTASPFLEGTVSL 683
             S  P++ S     T++A P++++ P      A  +PTTA+G S  T+T S       S+
Sbjct: 1403 VSTTPVVSSE--ASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSI 1460

Query: 684  APKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPL----ATLVLAPEIPKSVPSPSL 739
               N PV     +TL   P  S N PV  S   + +P      ++ ++     S    S+
Sbjct: 1461 PVSNTPVANSEASTLSTTPVDS-NSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSI 1519

Query: 740  PPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATA--SSKGTLTYLADSPSPL 797
            P + T   + +++ +S T A   V S+P    ++ S +  TA  +S  T TY ++  +PL
Sbjct: 1520 PVSTTTVASSEINSLSTTPA---VTSTPVTTYSQASSSPTTADGTSMQTSTY-SEGSTPL 1575

Query: 798  GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT 857
              S+   T    + + +    TPI + +   +  EAS    +S + +GS     T  +P+
Sbjct: 1576 -TSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEAS----SSTTAEGSS---MTISTPS 1627

Query: 858  PPSPKGAPTPSAVTPL-SPKGVTL--PPKETPTP-----SVVNLPFPKEGPATP------ 903
              SP     P + TP+ SP+  TL   P ++ +P      V + P P EG + P      
Sbjct: 1628 EGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTE 1687

Query: 904  ------------APKQAPALSMTSSSP----------KKARATPAPKGIPASP--SPKGA 939
                         P  + A+S  S++P           +AR++P      + P  +P   
Sbjct: 1688 GRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEG 1747

Query: 940  PTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG- 998
             TP  + P S     ++ +   + TP   + P      AT SP  A      T    +G 
Sbjct: 1748 TTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGM 1807

Query: 999  GPATPSP------KGAPTPPAVTPPSPKGSPAATPFPKGASTPPA-----ATPPSPKGSP 1047
             P T +P        +      T P    SP  T     +S  PA     AT    +GS 
Sbjct: 1808 TPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGST 1867

Query: 1048 AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP-SPKGAPMPP 1106
            A T +P    T  ++   +    PA  S         ++ P+   G + P S      PP
Sbjct: 1868 ALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPP 1927

Query: 1107 AATPPSPKGGLATPPHKGAPTTPAAT-PPSPKGGLATPPPKGAPTTPAATPPSPKGG--- 1162
              + P     +A+       TT A T  P      A+  P  A  T   TP   +G    
Sbjct: 1928 LTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPL 1987

Query: 1163 ----LATPPPKGAPTTPAATPPSPKGGLATPSPKG--APTTPAATPPSPKGGLATPSPKG 1216
                L+T     +  +  +T P      AT S +G  +PTT   T        +TPS + 
Sbjct: 1988 TSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQ----TSTPSER- 2042

Query: 1217 APTTPAATPP-------SPKGGLATPSPKGAPT-----TPAATPPSPKGGPAT--PPPKG 1262
              TTP A  P       S +G   + +P  + T     T A++  + +G   T   P +G
Sbjct: 2043 --TTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEG 2100

Query: 1263 AP--------TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA 1314
            +P        T P A+P +    L+T P     N  V+T       P   P +G  T   
Sbjct: 2101 SPLLTSIPLSTTPVASPEA--STLSTTPVDS--NSPVITSTEVSSSPI--PTEG--TSMQ 2152

Query: 1315 ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP--SSKGGPTTPSSKEGPTPP 1372
             +  S + +P T  P  + T  A +  S   T  +  +TP  +S    ++P++ EG + P
Sbjct: 2153 TSTYSDRRTPLTSMPV-STTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMP 2211

Query: 1373 AATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP----KKAPATPVTREGAATP 1428
             +TPS    P  + P     P + S     ++  V   +P     +A ++P T EG + P
Sbjct: 2212 TSTPSEGSTPFTSMPVSTM-PVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIP 2270

Query: 1429 S---KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVA 1485
            +       TP    PVS     A S       TP     P   +    SP        + 
Sbjct: 2271 TSTLSEGTTPLTSIPVS-HTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMP 2329

Query: 1486 TS-SSPKKAPATPAPMGAPTLPAVIPSSPKEVPA--------------TPSSRRDPIAPT 1530
            TS SS    P T  P+    + +   S+    PA              +P++  D   PT
Sbjct: 2330 TSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPT 2389

Query: 1531 ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590
            +T     TP T  P   + P   +  S   T  + T    P T S++ +SS     P+T 
Sbjct: 2390 STYSEGSTPLTSVPVSTM-PVVSSEASTHSTTPVDT--STPVTTSTEASSS-----PTTA 2441

Query: 1591 KGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPV-TPSSLKD 1649
            +G   P         TSP P E  TP A  P S    P   +  GT ++ PV T + +  
Sbjct: 2442 EGTSIP---------TSP-PSEGTTPLASMPVSTT--PVVSSEAGTLSTTPVDTSTPMTT 2489

Query: 1650 SPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKS 1709
            S  + +S T      VP ++    A +G T L  + V+  P ++P  +  +     +   
Sbjct: 2490 STEASSSPTTAEDIVVPIST----ASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSP 2545

Query: 1710 SATSPPICPDPSAKNGSKGPLSTVA----PAPLLPVQKDSSKTAKGKDASHSPKG---PL 1762
              TS  I    ++  G+  P ST +    P   +PV      +++    S +P     P+
Sbjct: 2546 VVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPV 2605

Query: 1763 APPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTL---PPKQQFLPS 1819
                  +S+P TA      +  P   S S       ++P+A S   TL   P   + L +
Sbjct: 2606 TTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVT 2665

Query: 1820 SPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVN------------MPTPKS 1867
            +      SP+       E   +P   P   S   P  ++LV+              TP  
Sbjct: 2666 TSTGTSSSPT-----TAEGSSMPTSTPGERS--TPLTNILVSTTLLANSEASTLSTTPVD 2718

Query: 1868 AGIPVPT--PSAKQPVTKNNKGSGTESDSDESVPELEEQDST--QATTQQAQLAAAAEID 1923
               PV T   ++  P T         + SD S P      ST   A+++ + ++  A   
Sbjct: 2719 TSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDT 2778

Query: 1924 EEPVSKAKQSRSEKKARKAMS 1944
              PV+ + ++ S     +  S
Sbjct: 2779 SIPVTTSTEASSSPTTAEVTS 2799



 Score =  264 bits (675), Expect = 6e-70
 Identities = 485/2134 (22%), Positives = 774/2134 (36%), Gaps = 295/2134 (13%)

Query: 2    PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
            P E T    +T  E   P      +P+S+ L  T+A+     T      P     P++ +
Sbjct: 849  PAEGTSMPTSTYSEGRTPLTS---MPVSTTLVATSAISTLSTT------PVDTSTPVTNS 899

Query: 62   NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAP----EAPTF--LPNLIGPPISPAA 115
             +A   P+ S   S P   P   S+  T++P  T P    EA T    P     P++ + 
Sbjct: 900  TEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTST 959

Query: 116  LALASPMIA---------PTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLT------- 159
             A +SP  A         P+   TP +S P++   +A       S  P +  T       
Sbjct: 960  EATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTE 1019

Query: 160  --SPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCV 217
              SPP  A   S    T      PSE  T L ++P   V       S    +ST P    
Sbjct: 1020 ASSPPPTAEGTSMPTST------PSEGSTPLTRMP---VSTTMVASSETSTLSTTPADTS 1070

Query: 218  TPMASIQSGVASLPQTT------PTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVS 271
            TP+ +     AS   TT      PT+T +  S  +    +S+ L+      +LS   PV 
Sbjct: 1071 TPVTTYSQ--ASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTT-PVD 1127

Query: 272  PPAALSLSTQSLPVVTSSQKTAGPNTPPD--------FPIS----LGSHLAPLHQSSFGS 319
                ++ ST++    T+++ T+ P +PP          P+S    + S    L  +   S
Sbjct: 1128 TSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDS 1187

Query: 320  VQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSV-IPPLPSRNEVVPATVAAFPVVA 378
               +  +  ++   PT +  S+  S+     P +RS  +  +P R+  V ++ A+    +
Sbjct: 1188 KTQVATSTEASSPPPTAEVTSMPTST-----PGERSTPLTSMPVRHTPVASSEASTLSTS 1242

Query: 379  PSVDKGPSTISSITCSPSGSLNVATSFSLSPTT--SLILKSSPNATYHYPLVAQMPVSSV 436
            P     P T S+ T S S +    TS   S T+  S +L S P +T    LV     S++
Sbjct: 1243 PVDTSTPVTTSAETSS-SPTTAEGTSLPTSTTSEGSTLLTSIPVST---TLVTSPEASTL 1298

Query: 437  GTTPL-----VVTN--------PCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAAL 483
             TTP+     VVT+        P    + PT+T+        P++S P++     S A  
Sbjct: 1299 LTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRT---PLTSIPVNTTLVASSAIS 1355

Query: 484  VMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVP------A 537
            +++   P + ST V T+     SP   +   + N   S      T   + T P      +
Sbjct: 1356 ILS-TTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEAS 1414

Query: 538  SLEGAPFSPAQAGLTTKKDPTVLPLVQ---AAPKNSPSFQSTS------SSPEIPLSPEA 588
            +L   P   +  G TT  + T  P      + P ++PS   T       S+  +  S  +
Sbjct: 1415 TLSATPVDTSTPG-TTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEAS 1473

Query: 589  TLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAG------PDSAGPLLKSSL-- 640
            TL+   +    P+    +  +SP     ++  I T S         P S   +  S +  
Sbjct: 1474 TLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINS 1533

Query: 641  --ITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTL 698
               TP V + P+ +   A  +PTTA GTS  T+T S       SL      V      TL
Sbjct: 1534 LSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTL 1593

Query: 699  PLVP-------TASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLP---PAGTPPGT 748
               P       TAS     + + + +   ++T      +  S+P  + P   P  +   T
Sbjct: 1594 STTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLST 1653

Query: 749  KKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSV------- 801
              VD  S       V+SSP          S     +  LT +    +P+  S        
Sbjct: 1654 TPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTT 1713

Query: 802  -----SPQT------KRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSP 850
                 +P T        P T +G++ P++     ++P++ +  S  P  S        +P
Sbjct: 1714 PVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATP 1773

Query: 851  ATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETP---TPSVVNLPFPKEGPA---TPA 904
              T +P   S +   +P+     S    TL    TP   TP    L    E      TP 
Sbjct: 1774 IDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPV 1833

Query: 905  PKQAPALSMT--SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA 962
               +P ++ T  SSSP  A  T      P+  S      P + T  +        +    
Sbjct: 1834 DSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAV 1893

Query: 963  PTPPAATPPSPKGGPATPSPKGAPT--PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK 1020
             + P  T       P T      PT  P    PP      +T +   +      T  +  
Sbjct: 1894 TSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADT 1953

Query: 1021 GSPAATPFPKGASTPPAA------TPPSPKGS------PAATPLPKGAPTTPAATLPSPK 1068
             +P  T + + +S+P  A      TP   +GS      P +T L   +  +  +T P   
Sbjct: 1954 RTPVTT-YSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDT 2012

Query: 1069 GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP---MPPAATPPSPKGG--LATPPHK 1123
              PAT S +G+ +P  A   S +   +TPS +  P   MP + T      G  L+T P  
Sbjct: 2013 STPATTSTEGSSSPTTAGGTSIQ--TSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVD 2070

Query: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1183
                   +T  S     ++   +G+  T +A  PS    L T  P    TTP A+P +  
Sbjct: 2071 SKTQVTNSTEAS-----SSATAEGSSMTISA--PSEGSPLLTSIPLS--TTPVASPEAST 2121

Query: 1184 GGLATPSPKGAP---TTPAATPPSPKGGLA----TPSPKGAPTT--PAATPPSPKGGLAT 1234
                TP    +P   +T  ++ P P  G +    T S +  P T  P +T       ++T
Sbjct: 2122 LS-TTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAIST 2180

Query: 1235 PSPKGAPT-TPAATPPSPKGGPATPPPKGAPT--PPAATPPSLKGGLATPPHKGAPNPAV 1291
             S     T TP       +  P T      PT  P   + P     ++T P   +    +
Sbjct: 2181 LSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTL 2240

Query: 1292 VTPPSPKGGPATSPPKGAPTPPAA---TPPSPKGSPGTPPPKGAP---TPPAVTPPSPKG 1345
               P     P T+  +   +P  A   + P+   S GT P    P   T  A +  S   
Sbjct: 2241 SATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLS 2300

Query: 1346 TPTLPATTP--SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPT 1403
            T  + + TP  +S    + P + EG + P +T S    P    P      A        T
Sbjct: 2301 TTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLST 2360

Query: 1404 SPAVIPLSPKKAPATPVTR--EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSS 1461
            +PA          +TPVT   +  ++P+  D T    +  S    P TS P       SS
Sbjct: 2361 TPA--------DTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSS 2412

Query: 1462 KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATP- 1520
            +        T P     P       SSSP  A  T  P   P+     P +   V  TP 
Sbjct: 2413 EASTHS---TTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPS-EGTTPLASMPVSTTPV 2468

Query: 1521 -SSRRDPIAPT----ATLLSKKTPATLAPKEA--LIPPAMTVPS--------PKKTPAIP 1565
             SS    ++ T    +T ++  T A+ +P  A  ++ P  T           P  T  + 
Sbjct: 2469 VSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVA 2528

Query: 1566 TPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPE 1625
            +P+ +  + +  +++SP   +      A S +   +P +  S       + P  T P   
Sbjct: 2529 SPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLAS 2588

Query: 1626 KGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVL 1685
               +T +     TS PVT S+   S  + A  T    +T  + S         T+L  +L
Sbjct: 2589 SEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVS---------TSLTSIL 2639

Query: 1686 VAPAP----ESTPIITAP--TRKGPQTKKSSATSPPICPDPSAKNGSKG----PLSTVAP 1735
            V+  P    E++ + T P  TR    T   +++SP      S    + G    PL+ +  
Sbjct: 2640 VSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILV 2699

Query: 1736 APLLPVQKDSSKTAK-----------GKDASHSPKGP------LAPPESKASTPLTAAAF 1778
            +  L    ++S  +              +AS SP         ++ P S  STPLT+   
Sbjct: 2700 STTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTP-SDGSTPLTSILV 2758

Query: 1779 EKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPL------ 1832
              +      AS  +  +   S+P+  S   +  P    + S P       S PL      
Sbjct: 2759 STLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVN 2818

Query: 1833 -APADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSA-GIPVPTPSAKQ----------- 1879
              P    E    +   P+    P  +      +P +A GI VP  +A +           
Sbjct: 2819 HTPVASSE-AGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVS 2877

Query: 1880 --PVTKNNKGSGTESDSDESVPELEEQDSTQATT 1911
              PV  +   + + +  D S+P     + + + T
Sbjct: 2878 TTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPT 2911



 Score =  262 bits (670), Expect = 2e-69
 Identities = 459/1932 (23%), Positives = 724/1932 (37%), Gaps = 318/1932 (16%)

Query: 6    TETVPATEQELPQPQAETAVLPMSSA---------LSVTAALGQPGPTLPPPCSPAPQQC 56
            T    +TE   P P AE   +P S++         + V+  +     T     +PA    
Sbjct: 2308 TPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTST 2367

Query: 57   PLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAP----EAPTF--LPNLIGPP 110
            P++  +QA   P+ +   S P       S+  T++P+ T P    EA T    P     P
Sbjct: 2368 PVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTP 2427

Query: 111  ISPAALALASPMIA---------PTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSP 161
            ++ +  A +SP  A         P+   TP +S P++   +        S  P +  T P
Sbjct: 2428 VTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTST-P 2486

Query: 162  PSVAVAESGSVITLSAPIAP----SEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCV 217
             + +   S S  T    + P    SE  T L  +P  V   P  +P    + ST P    
Sbjct: 2487 MTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIP--VSTTPVASPEASTL-STTPVDSN 2543

Query: 218  TPMAS---IQSGVASLPQTT-PTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPP 273
            +P+ +   I S   S   T+ PT+T +  S  ++   +S+  ++     +LS   PV   
Sbjct: 2544 SPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTT-PVDT- 2601

Query: 274  AALSLSTQSLPVVTSSQKTAGPNTPPD--FPISLGSHLAPLHQSSFGSVQLLGQTGPSAL 331
                    S+PV TS++ ++ P T  D   PIS  S ++    S   S   +  +  S L
Sbjct: 2602 --------SIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTL 2653

Query: 332  SDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSV--DKGPSTIS 389
            S   V T ++  +STG S     +    +P+      +T     +V+ ++  +   ST+S
Sbjct: 2654 STTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLS 2713

Query: 390  SITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTI 449
            +     S  +  +   S SPTT+       +     P     P++S+    LV T P   
Sbjct: 2714 TTPVDTSTPVTTSAEASSSPTTA----EGTSMRISTPSDGSTPLTSI----LVSTLPVAS 2765

Query: 450  AAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVS-PP 508
            + A T +   A   S P+++   ++  PT+     M    P E ST + +   +PV+  P
Sbjct: 2766 SEASTVS-TTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTS---MPVNHTP 2821

Query: 509  LPDPE--DLKNLPSSVLVKFPTQKDLQTVPASLEG--APFSPAQAGLTTKKDPTVLPLVQ 564
            +   E   L   P        T     + P + EG   P S A  G T     T +P V 
Sbjct: 2822 VASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLL---TSIP-VS 2877

Query: 565  AAPKNSPSFQSTSSSPEIPLSPEATLAKKSL------GEPLPIGKPASSMTSPLGVNSSA 618
              P  S    + S++P     P  T  + S       G  +PI  P S +++PL    ++
Sbjct: 2878 TTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTP-SEVSTPL----TS 2932

Query: 619  SVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLE 678
             ++ T   AG +++     +   TP     P+ ++  A  +PTTA+GTS   +T      
Sbjct: 2933 ILVSTVPVAGSEAS-----TLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRT 2987

Query: 679  GTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPS 738
               S++    PV     +TL   P A  + PV  S + + +P  T      IP S PS  
Sbjct: 2988 PLTSMSVSTMPVASSEASTLSRTP-ADTSTPVTTSTEASSSP--TTAEGTGIPISTPSEG 3044

Query: 739  LPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLG 798
              P  + P       +S T    P AS+    P + +    T+      T ++ SP+P  
Sbjct: 3045 STPLTSIP-------VSTTPVAIPEASTLSTTPVDSNSPVVTS------TEVSSSPTPA- 3090

Query: 799  VSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTP 858
                         +G++ P +     S+P++ V  S  P  S +      +P  T +P  
Sbjct: 3091 -------------EGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVT 3137

Query: 859  PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP 918
             S     T +  +P + +G ++P   T TPS        EG           + + SS  
Sbjct: 3138 TS-----TEAHSSPTTSEGTSMP---TSTPS--------EGSTPLTYMPVSTMLVVSSED 3181

Query: 919  KKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATP-------- 970
                ATP     P + S +   +  A     P   P+         P + TP        
Sbjct: 3182 STLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASI 3241

Query: 971  ----PSPKGGPATPSPKGAPTPPAA-------TPPSPKGGPATPSP------KGAPTPPA 1013
                P     P T S + + +PP A       + PS    P T  P        + T   
Sbjct: 3242 LSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTL 3301

Query: 1014 VTPPSPKGSPAATPFPKGASTPPAA---TPPSPKGSPAATPLPKGA-PTTPA-------- 1061
             T P+   +P  T + + +S+PP A   + P+   S  +TPL   +  TTP         
Sbjct: 3302 STTPADTSTPVTT-YSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTL 3360

Query: 1062 ATLPSPKGGPATPSLKGAPTPPAATPPS-PKGGPATPSPKGAPMPPAATP--PSPKGGLA 1118
            +T P     P T S + + +P  A   S P   P+  +   A MP + TP   S    L+
Sbjct: 3361 STTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLS 3420

Query: 1119 TPPHKG----APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT 1174
            T P         +T A++ P+   G + P    + T+  +TP S      TP      +T
Sbjct: 3421 TTPVDSNTLVTTSTEASSSPTIAEGTSLPT---STTSEGSTPLSIMPLSTTPVASSEAST 3477

Query: 1175 PAATPPSPKGGLATPSP-KGAPTTPAAT--PPSPKGGLATP-SPKGAPTTPAA------- 1223
             + TP      + T SP   +PTT   T  P S  G  +TP +     TTP A       
Sbjct: 3478 LSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTL 3537

Query: 1224 -TPPSPKGGLATPSPKGAP-------TTPAATPPSPKGGPATPPPKGAP---TPPAATPP 1272
             T P       T S + +        TT   + PS      T     +    +  A+TP 
Sbjct: 3538 STTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPS 3597

Query: 1273 SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA------PTPPAATPPSPKGSPGT 1326
            +     +TP      + +  TPP     P ++P + +      P    +   S  G+  T
Sbjct: 3598 TPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTAST 3657

Query: 1327 PP-----PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGG 1381
             P     P    T  + +P +P+GT T+P  TPS    P T      P       S +G 
Sbjct: 3658 LPVDTSTPVITSTQVSSSPVTPEGT-TMPIWTPSEGSTPLTTM----PVSTTRVTSSEGS 3712

Query: 1382 PAMTPPSPKRGPAIPSPKG-------DPTSPAV-IPLSPKK------APATPVTR-EGAA 1426
               TP      P   S +        D T+ +V +P+             TPVTR   ++
Sbjct: 3713 TLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESS 3772

Query: 1427 TPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPP-----------SP 1475
            TPS     P   T +S+     T+A +G  +  + +G  T+P  T             SP
Sbjct: 3773 TPS----IPSVYTSMSM-----TTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISP 3823

Query: 1476 KEPPAPKQVATSSSPKKAPATP----APMGAPTLPAVIPS------SPKEVPATP---SS 1522
                +P + +T S+P    +TP       G+ ++PA + +      S +  P T    S+
Sbjct: 3824 ISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVST 3883

Query: 1523 RRDPIAPTATLLSKK--------TPATLAPKEALIPPAMTVP--------SPKKTPAIP- 1565
                  P A++ S          TP+T       IP A T+         +P  T  IP 
Sbjct: 3884 TLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPS 3943

Query: 1566 ---TPKEAPATPSSKEASSPPAVT------PSTYKGAP----SPKELLIPPAVTSPSP-- 1610
               T   A   P++  A S P +T      PST   +     S  +    PA+T+ +P  
Sbjct: 3944 TPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLT 4003

Query: 1611 ----KEAPTPPAVTPPSPEKGPATPAPKGTP------TSPPVTPSSLKDSPTSPASVTCK 1660
                  AP+ P  T        +T +   TP      T+ PVTPSS    P++  S T  
Sbjct: 4004 YVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHT-- 4061

Query: 1661 MGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDP 1720
            +  T P A    P     T+     V P      + T  TR  P T+ +S  +      P
Sbjct: 4062 IPPTFPPAHSSTPP---TTSASSTTVNP----EAVTTMTTRTKPSTRTTSFPTVTTTAVP 4114

Query: 1721 SAKNGSKGPLST 1732
            +       P ST
Sbjct: 4115 TNTTIKSNPTST 4126



 Score =  257 bits (657), Expect = 7e-68
 Identities = 468/2095 (22%), Positives = 747/2095 (35%), Gaps = 249/2095 (11%)

Query: 27   PMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPS---TIASTPLEVPFP 83
            P++++   +++   P  T  P  + +    PL++   ++   + S   T+ +TP+E+  P
Sbjct: 187  PLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTP 246

Query: 84   QSSSGTALPLGTAPEAPTF---LPNLIGPPIS--PAALALASPMIAPTLKGTP------- 131
             + S  A    T  E P+     P+    P++  P ++ L     A TL  TP       
Sbjct: 247  VTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPV 306

Query: 132  ------SSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPK 185
                  SSS   A     P S     + P  L ++P S     +  + TLS     +   
Sbjct: 307  ITSTEASSSPTTAEGTSIPTSTYTEGSTP--LTSTPASTMPVATSEMSTLSITPVDTSTL 364

Query: 186  TNLNKVPSEVVPNPKGT-------------------------PSPPCIVSTVPYHCVTPM 220
               +  PS +    + T                          S     ST+P    T  
Sbjct: 365  VTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKT-F 423

Query: 221  ASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLST 280
             +  S  +S P T   T++A ++P    T ++S+ +S     S       + P       
Sbjct: 424  VTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQV 483

Query: 281  QSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTIS 340
             +    +SS  TA  N+ P    S GS   PL   S  ++ +      +  + P   +  
Sbjct: 484  TTSTEASSSPPTAEVNSMPTSTPSEGS--TPLTSMSVSTMPVASSEASTLSTTPVDTSTP 541

Query: 341  VDHSSTGAS---YPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSG 397
            V  SS  +S    P   S+    PS        +   PV    V    ++ +S T + S 
Sbjct: 542  VTTSSEASSSSTTPEGTSIPTSTPSEGS---TPLTNMPVSTRLVVSSEASTTSTTPADSN 598

Query: 398  SLNVATSFSLSPTTSLILKSSPNATY------------HYPLVAQMPVSSVGTTPLVVTN 445
            +    +S + S +T+    S P +TY               LVA    S++ TTP+    
Sbjct: 599  TFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNT 658

Query: 446  PCTIAAAPTTTFEVA----------TCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPST 495
            P T +   T++   A          T  S P++S P++     S  A  ++   P + ST
Sbjct: 659  PVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLS-TTPVDTST 717

Query: 496  QVATTLRIPVSPPLPD----PEDLKNLPSSVLVKFPTQKDLQT--VPASLEGAPFSPAQA 549
             V T+     SP   D    P    +  S+ L   P  K L T    ++L   P      
Sbjct: 718  PVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLD-TST 776

Query: 550  GLTTKKDPTVLPL--------VQAAPKNSPSFQSTSSSPEIPLSPEA-TLAKKSLGEPLP 600
             +TT  + +  P         +    + SP   S   S     SPEA TL+   +    P
Sbjct: 777  HITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSP 836

Query: 601  IGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLI----------TPTVAAFPL 650
            +       +SP     ++    T S          + ++L+          TP   + P+
Sbjct: 837  VTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPV 896

Query: 651  ESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPV 710
             ++  A  +PTT++GTS  T+T         S+     PV      TL   P    + PV
Sbjct: 897  TNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATP-VDTSTPV 955

Query: 711  APSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKEC 770
              S + T +P  T      IP S PS    P  + P       +SHT      AS+    
Sbjct: 956  TTSTEATSSP--TTAEGTSIPTSTPSEGTTPLTSTP-------VSHTLVANSEASTLSTT 1006

Query: 771  PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSP 830
            P  DS    T S++      A SP P     S  T  P   +GS    TP+  +  PVS 
Sbjct: 1007 PV-DSNTPLTTSTE------ASSPPPTAEGTSMPTSTP--SEGS----TPLTRM--PVST 1051

Query: 831  VEASFLPENSLSFQGSKDS-PATTHS--------------PTPPSPKGAPTPSAVTPLSP 875
               +    ++LS   +  S P TT+S              PT    +G+ TP    P+S 
Sbjct: 1052 TMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGS-TPLTSVPVST 1110

Query: 876  KGVTLPPKET--PTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPAS 933
            + V      T   TP   ++P      A+ +P  A   S+ +S P +     A   +  +
Sbjct: 1111 RLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTT 1170

Query: 934  PSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP 993
                      + TP   K   AT +   +P P A     P   P   S      P   TP
Sbjct: 1171 LVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTP 1230

Query: 994  -PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052
              S +    + SP    T P  T      SP      +G S P + T    +GS   T +
Sbjct: 1231 VASSEASTLSTSPVDTST-PVTTSAETSSSPTTA---EGTSLPTSTT---SEGSTLLTSI 1283

Query: 1053 PKGAP--TTPAA----TLPSPKGGPATPS--LKGAPTPPAAT--PPSPKGGPATPSPKGA 1102
            P      T+P A    T P    GP   S  +  +PTP   T  P S      TP     
Sbjct: 1284 PVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPL-TSI 1342

Query: 1103 PMPPAATPPSPKGGLATPPHKGA----PTTPAATPPSPKGGLATP---PPKGAPTTPAAT 1155
            P+       S    L+T P   +     +T A + P+   G + P   P +G  TTP  +
Sbjct: 1343 PVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEG--TTPLTS 1400

Query: 1156 PPSPKGGLATPPPKGAPTTPAATP-----PSPKGGLATPSPKGAP--TTPAATPPSPKGG 1208
             P       TP      +T +ATP     P      AT SP  A   + P +TP   K  
Sbjct: 1401 IPVS----TTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTP 1456

Query: 1209 LA------TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP--ATPPP 1260
            L       TP      +T + TP      + T       +T  ++ P+P  G   A   P
Sbjct: 1457 LKSIPVSNTPVANSEASTLSTTPVDSNSPVVT-------STAVSSSPTPAEGTSIAISTP 1509

Query: 1261 KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSP 1320
                T   + P S     ++  +  +  PAV + P      A+S P  A      T    
Sbjct: 1510 SEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYS 1569

Query: 1321 KGS-PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHK 1379
            +GS P T  P       +    +   TP    T  ++    ++ ++ EG +   +TPS +
Sbjct: 1570 EGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPS-E 1628

Query: 1380 GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPA-- 1437
            G P +T   P     + SP+    S    P+       T      + TP++G   P +  
Sbjct: 1629 GSPLLT-SIPVSTTPVASPEASTLS--TTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTY 1685

Query: 1438 ------VTPVSLKKAP-ATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP 1490
                  +T ++++  P A+SA      TP    D + P  T    +  P   +   +S P
Sbjct: 1686 TEGRTPLTSITVRTTPVASSAISTLSTTPV---DNSTPVTTSTEARSSPTTSE--GTSMP 1740

Query: 1491 KKAPA---TPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPA--TLAPK 1545
               P+   TP      +   V+ S    + ATP     P+  +    S  T A  T  P 
Sbjct: 1741 NSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPT 1800

Query: 1546 EALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAV 1605
              L      + S   +  +    EA    ++   S+ P VT +    +P+P E     ++
Sbjct: 1801 STLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAE---GTSI 1857

Query: 1606 TSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATV 1665
             + +P E  T     P S     A+       T+P VT + +       +S T   G+++
Sbjct: 1858 ATSTPSEGSTALTSIPVSTTT-VASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSM 1916

Query: 1666 PQAS--KGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPI------C 1717
            P ++  +G P       +    VA +  +T   T    + P T  S A+S P        
Sbjct: 1917 PTSTPREGRPPLTS-IPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSM 1975

Query: 1718 PDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTA-----KGKDASHSPKGPLAPPESKASTP 1772
            P P+   GS  PL+++  +  L V  ++S  +         A+ S +G  +P  +  ++ 
Sbjct: 1976 PTPAYSEGST-PLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSI 2034

Query: 1773 LTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPL 1832
             T+   E+  P       +          L+ +PV +         +S     E  S  +
Sbjct: 2035 QTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTI 2094

Query: 1833 -APADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTE 1891
             AP++   LL  IP        P  S L   P   ++ +   T  +  P+        T 
Sbjct: 2095 SAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTS 2154

Query: 1892 SDSDESVPELEEQDSTQATTQQA--QLAAAAEIDEEPVSKAKQSRSEKKARKAMS 1944
            + SD   P      ST      A   L+        PV+ + ++RS     +  S
Sbjct: 2155 TYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTS 2209



 Score =  257 bits (656), Expect = 9e-68
 Identities = 495/2211 (22%), Positives = 804/2211 (36%), Gaps = 341/2211 (15%)

Query: 6    TETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQAS 65
            T+   +TE     P AE   +P S+          P     P  S +    P++++    
Sbjct: 481  TQVTTSTEASSSPPTAEVNSMPTST----------PSEGSTPLTSMSVSTMPVASSEA-- 528

Query: 66   PFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEA---PTFLPNLIGPPIS--PAALALAS 120
                 ST+++TP++   P ++S  A    T PE    PT  P+    P++  P +  L  
Sbjct: 529  -----STLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVV 583

Query: 121  PMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVIT---LSA 177
               A T   TP+ S           S + SS+      TS P+   +E G+ IT   +S 
Sbjct: 584  SSEASTTSTTPADSNTFVTT-----SSEASSSSTTAEGTSMPTSTYSERGTTITSMSVST 638

Query: 178  PIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTT 237
             +  S   + L+  P +    P  T +     ST       P ++   G   L      T
Sbjct: 639  TLVASSEASTLSTTPVD-SNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNT 697

Query: 238  TLAIASPQVKDTTISSVLISPQNPGSLSLKG------------PVSPPAALSLSTQSLPV 285
            TL  +S   + +T+S+  +    P + S +             P S P+  S    S+PV
Sbjct: 698  TLVASS---EASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPV 754

Query: 286  VTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGP-SALSDPTVKTISVDHS 344
              +   ++  +T    P+   +H+    ++S       G + P S  S+ +    S+  S
Sbjct: 755  SKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVS 814

Query: 345  STGASYPSQRSV-IPPLPSRNEVVPAT-VAAFPVVAPSVDKGPSTISS----ITCSPSGS 398
             T  + P   ++   P+ S + V  +T V++ P  A       ST S     +T  P  +
Sbjct: 815  ITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVST 874

Query: 399  LNVATSFSLSPTTSLILKSSP--NAT--YHYPLVAQ---MPVSSVG------------TT 439
              VATS   + +T+ +  S+P  N+T     P  ++   MP S+ G            TT
Sbjct: 875  TLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTT 934

Query: 440  PLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVAT 499
            P+V +   T++A P  T       S P+++   +   PT+     +    P E +T + +
Sbjct: 935  PVVSSEARTLSATPVDT-------STPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTS 987

Query: 500  TLRIPVSPPL---PDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGA--PFSPAQAGLTTK 554
            T   PVS  L    +   L   P        T  +  + P + EG   P S    G T  
Sbjct: 988  T---PVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPL 1044

Query: 555  KDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGV 614
                V   + A+ + S    + S++P    +P  T ++ S       G    + T   G 
Sbjct: 1045 TRMPVSTTMVASSETS----TLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGS 1100

Query: 615  NSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTAS 674
                SV  +        A  L      TP   + P+ ++  A  +PTTA+GTS  T   S
Sbjct: 1101 TPLTSVPVSTRLVVSSEASTL----STTPVDTSIPVTTSTEASSSPTTAEGTSIPT---S 1153

Query: 675  PFLEGTVSLAPKNHPV--------KEGTLTTLPL-----VPTASENCPVAPSPQNTCAPL 721
            P  EGT  LA  + PV        +  TL+T P+     V T++E     P+ + T  P 
Sbjct: 1154 PPSEGTTPLA--SMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPT 1211

Query: 722  ATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGIS----HTSALAPVASSPKECPTEDSGA 777
            +T        +S P  S+P   TP  + +   +S     TS     ++     PT   G 
Sbjct: 1212 ST-----PGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGT 1266

Query: 778  S---ATASSKGTL-------TYLADSPSPLGVSVSPQTKRPP--TKKGSAGPDTPIGNLS 825
            S   +T S   TL       T L  SP    +  +P   + P  T    +   TP    S
Sbjct: 1267 SLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTS 1326

Query: 826  SPVS------------PVEASFLPENSLSFQGS----KDSPATTHS---PTPPSPKGAPT 866
             P S            PV  + +  +++S   +      +P TT +    +P + +G   
Sbjct: 1327 MPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSM 1386

Query: 867  PSA-----VTPLSPKGVTLPP-------KETPTPSVVNLPFPKEGPATPAPKQAPALSMT 914
            P++      TPL+   V+  P         + TP   + P      AT +P  A  +S+ 
Sbjct: 1387 PNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIP 1446

Query: 915  SSSPKKARATPAPKGIPASPSP-KGAPTPPAATPPSPKGGPATPSP--KWAPTPP----- 966
            +S+P + + TP  K IP S +P   +     +T P     P   S     +PTP      
Sbjct: 1447 TSTPSEGK-TPL-KSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSI 1504

Query: 967  AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPA-TPSPKGAPTPPAVTPPSPKGSPAA 1025
            A + PS      T  P    T  ++   S    PA T +P    +  + +P +  G+   
Sbjct: 1505 AISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQ 1564

Query: 1026 TPFPKGASTPPAATP-------PSPKGSPAATPLPKGAPTTPAA-------------TLP 1065
            T      STP  + P        S   + + TP+      T +              T+ 
Sbjct: 1565 TSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTIS 1624

Query: 1066 SP-KGGPATPSLKGAPTPPA-------ATPPSPKGGP--------ATPSP-KGAPMPPAA 1108
            +P +G P   S+  + TP A       +T P     P        ++P+P +G  MP + 
Sbjct: 1625 TPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTST 1684

Query: 1109 -----TPPSPKGGLATPPHKGAPTTPAATPPSPKGGLAT-PPPKGAPTT------PAATP 1156
                 TP +      TP    A +T + TP      + T    + +PTT      P +TP
Sbjct: 1685 YTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTP 1744

Query: 1157 PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1216
                  L + P    P   +         + T +P    T   ++P + +G     S   
Sbjct: 1745 SEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLS 1804

Query: 1217 APTTPAATPPSPKGGLA---------TPSPKGAP---TTPAATPPSPKGGP--ATPPPKG 1262
               TP  + P     +A         TP    +P   +T  ++ P+P  G   AT  P  
Sbjct: 1805 EGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSE 1864

Query: 1263 APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG 1322
              T   + P S     ++  +  +  PAV + P       +S P    T   ++ P+   
Sbjct: 1865 GSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSP---TTADGSSMPTSTP 1921

Query: 1323 SPGTPPPKGAPTPPAVTPPS--------------PKGTPTLPATTPSSKGGPT--TPSSK 1366
              G PP    P        S              P  T +  +++P++  G +  TP+  
Sbjct: 1922 REGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYS 1981

Query: 1367 EGPTPPAATP-------SHKGGPAMTPPSPKRGPAIPSPKG--DPTSP--AVIPLSPKKA 1415
            EG TP  + P       S +     T P     PA  S +G   PT+     I  S    
Sbjct: 1982 EGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSE 2041

Query: 1416 PATPVTREGAAT----PSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471
              TP+     +T     S+G+    + TPV   K   T++ +   +  +     T+ A +
Sbjct: 2042 RTTPLAGMPVSTTLVVSSEGNTL--STTPVD-SKTQVTNSTEASSSATAEGSSMTISAPS 2098

Query: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTA 1531
              SP     P      +SP+ +  +  P+ + +   VI S+  EV ++P         T+
Sbjct: 2099 EGSPLLTSIPLSTTPVASPEASTLSTTPVDSNS--PVITST--EVSSSPIPTEGTSMQTS 2154

Query: 1532 TLLSKKTPATLAPKEALIPPAMTVPSPKKTPA-----IPTPKEAPATPSSKEASSPPAVT 1586
            T   ++TP T  P    +  +  + +   TP      +    EA ++P++ E +S P  T
Sbjct: 2155 TYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTST 2214

Query: 1587 PSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAP---KGTP------ 1637
            PS      +   +   P VTS +   + TP   + P      AT +P   +GT       
Sbjct: 2215 PSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTL 2274

Query: 1638 -------TSPPVTPSSLKDSPTSPASVTCKMG----ATVPQASKGLPAKKG---PTA--- 1680
                   TS PV+ + + +S  S  S T         T  +AS   P  +G   PT+   
Sbjct: 2275 SEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSS 2334

Query: 1681 ----------LKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD-----PSAKNG 1725
                      +   +VA    ST   T      P T  S A S P   D      S  + 
Sbjct: 2335 EGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSE 2394

Query: 1726 SKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKP 1785
               PL++V P   +PV    + T        S   P+      +S+P TA         P
Sbjct: 2395 GSTPLTSV-PVSTMPVVSSEASTHSTTPVDTST--PVTTSTEASSSPTTAEGTSIPTSPP 2451

Query: 1786 ESASVSAAPSPPVSLPLAPSPVPTL---------PPKQQFLPSSPGLVLESPSKPLAPAD 1836
               +   A  P  + P+  S   TL         P       SS     E    P++ A 
Sbjct: 2452 SEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTAS 2511

Query: 1837 E-DELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSD 1895
            E   LL  IP        P  S L   P   ++ +   T  +    +       T + S+
Sbjct: 2512 EGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSE 2571

Query: 1896 ESVPELEEQDSTQ--ATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMS 1944
             S P      ST+  A+++ + L+        PV+ + ++ S     K  S
Sbjct: 2572 GSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTS 2622



 Score =  249 bits (635), Expect = 3e-65
 Identities = 460/2053 (22%), Positives = 737/2053 (35%), Gaps = 312/2053 (15%)

Query: 10   PATEQ--ELPQPQAETAVLPMSSA-LSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASP 66
            P T +   +P         P++S  +S T  L     TL    +P     P++ + +A+ 
Sbjct: 1731 PTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLS--ATPIDTSTPVTTSTEATS 1788

Query: 67   FPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPT 126
              SP+T   T   +P    S G   PL + P + T + N     +S   +   SP++  T
Sbjct: 1789 --SPTTAEGT--SIPTSTLSEGMT-PLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTST 1843

Query: 127  LKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKT 186
                 SS  P    ++A  +  + S    ++  S  +VA +E+ ++ T   P   S P T
Sbjct: 1844 --AVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLST--TPAVTSTPVT 1899

Query: 187  NLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQ---SGVASLPQTTPTTTLAIAS 243
               +V S   P      S P   ++ P     P+ SI    + VAS    T +TTLA   
Sbjct: 1900 TYAQVSSS--PTTADGSSMP---TSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTR 1954

Query: 244  PQVKDTTISSVLISPQNPGSLSLKGPV-----SPPAALSLSTQ----------------- 281
              V  TT S    SP      S+  P      +P  ++ LST                  
Sbjct: 1955 TPV--TTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDT 2012

Query: 282  SLPVVTSSQKTAGPNTPPDFPISLGS---HLAPLHQSSFGSVQLLGQTGPSALSDP---- 334
            S P  TS++ ++ P T     I   +      PL      +  ++   G +  + P    
Sbjct: 2013 STPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSK 2072

Query: 335  TVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCS 394
            T  T S + SS+  +  S  ++  P      +    ++  PV +P      ST+S+    
Sbjct: 2073 TQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEA----STLSTTPVD 2128

Query: 395  PSGSLNVATSFSLSP--TTSLILKSSPNATYHYPL---------VAQMPVSSVGTTPL-- 441
             +  +  +T  S SP  T    +++S  +    PL         VA   +S++ TTP+  
Sbjct: 2129 SNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDT 2188

Query: 442  --VVTNPCTIAAAPTTTFEVATCVSPP------MSSGPISNIEPTSPAALVMAPVAPKEP 493
               VTN     ++PTT+   +   S P       +S P+S +   +  A  ++   P + 
Sbjct: 2189 STPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLS-ATPVDT 2247

Query: 494  STQVATTLR------------IPVSPPLPDPEDLKNLP-SSVLVKFPTQKDLQTVPASLE 540
            ST V T+              IP S        L ++P S  LV       L T P    
Sbjct: 2248 STPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVD-S 2306

Query: 541  GAPFSPAQAGLTTKK--DPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEP 598
              PF+ +    +     + T +P   ++  N+P  +   S+  +     +TL+       
Sbjct: 2307 NTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTS 2366

Query: 599  LPIGKPASSMTSPLGVNSSASVIKTDSYAG------PDSAGPLLKSSL----ITPTVAAF 648
             P+   + + +SP   + ++    T S         P S  P++ S       TP   + 
Sbjct: 2367 TPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTST 2426

Query: 649  PLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAP---KNHPV---KEGTLTTLPL-- 700
            P+ ++  A  +PTTA+GTS  T   SP  EGT  LA       PV   + GTL+T P+  
Sbjct: 2427 PVTTSTEASSSPTTAEGTSIPT---SPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDT 2483

Query: 701  ---VPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHT 757
               + T++E      + ++   P++T      +  S+P  + P A     T     +   
Sbjct: 2484 STPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSN 2543

Query: 758  SALAPVASSPKECPTEDSGASATASSKGTLTY------------------------LADS 793
            S   PV +S +      S  SA  +S  T TY                        L+ +
Sbjct: 2544 S---PVVTSTE---ISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTT 2597

Query: 794  PSPLGVSVSPQTKR---PPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSP 850
            P    + V+  T+    P T K ++ P +    +S+ ++ +  S +P  S        +P
Sbjct: 2598 PVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTP 2657

Query: 851  ATTH---------SPTPPSPKGAPTPSAV-----TPLS-------------PKGVTLPPK 883
              T          S +P + +G+  P++      TPL+                ++  P 
Sbjct: 2658 VDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPV 2717

Query: 884  ETPTPSVVNL-----PFPKEGPA----TPAPKQAP-------ALSMTSSSPKKARATPAP 927
            +T TP   +      P   EG +    TP+    P        L + SS       T   
Sbjct: 2718 DTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVD 2777

Query: 928  KGIPASPSPKGAPTPPAA-------TPPSPKGGPATPSPKWAPTPPAA-------TPPSP 973
              IP + S + + +P  A       + PS    P T  P    TP A+       T P  
Sbjct: 2778 TSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPV-NHTPVASSEAGTLSTTPVD 2836

Query: 974  KGGPATPSPKGAPTPPAAT------PPSPKGGPATPSPKGAPTPPAVTPPSPKGS-PAAT 1026
               P T S K + +P  A         + +G     S   + TP A +  S   + P  T
Sbjct: 2837 TSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDT 2896

Query: 1027 PFPKGASTPPAATPPSPKGS--PAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPA 1084
              P   ST  +++P + +G+  P +TP     P T       P  G    +L   P    
Sbjct: 2897 SIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTR 2956

Query: 1085 ATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP 1144
                +     ++P+       P +TP   +  L +      P   +      +    T  
Sbjct: 2957 TPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTST 3016

Query: 1145 PKGAPTTPAATPPSPKGG---LATPPPKGAP-------TTPAATPPSPKGGLATPSPKGA 1194
            P    T  +++P + +G    ++TP     P       TTP A P +      TP    +
Sbjct: 3017 PVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLS-TTPVDSNS 3075

Query: 1195 P---TTPAATPPSPKGGLATP----SPKGAPTT--PAATPPSPKGGLATPSPKGAPT-TP 1244
            P   +T  ++ P+P  G + P    S    P T  P +T P     ++T S     T TP
Sbjct: 3076 PVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTP 3135

Query: 1245 AATPPSPKGGPATPPPKGAPT--PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPA 1302
              T       P T      PT  P   + P     ++T     + +  +   P     P 
Sbjct: 3136 VTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPV 3195

Query: 1303 TSPPKGAPTPPAATPPSPKGSP--GTPPPKGAP---TPPAVTPPSPKGTPTLPATTP--S 1355
            T+  +   +  A     P  +P  G  P    P   TP A +  S   T  + + TP  +
Sbjct: 3196 TTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTT 3255

Query: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415
            S    ++P + EG + P +TPS    P  + P      A        T+PA         
Sbjct: 3256 STEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPA--------D 3307

Query: 1416 PATPVTR--EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPP 1473
             +TPVT   + +++P   D T    +  S    P T+         SS+   TL   T P
Sbjct: 3308 TSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEAS-TLS--TTP 3364

Query: 1474 SPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATP--SSRRDPIAPTA 1531
                 P       S SP  A  T  P  +P+     P +   V  TP  SS  + ++ T 
Sbjct: 3365 VDTSTPVTTSTEASLSPTTAEGTSIPTSSPS-EGTTPLASMPVSTTPVVSSEVNTLSTTP 3423

Query: 1532 ----TLLSKKTPATLAPKEA---LIPPAMTVPSPKKTPAIP---TP---KEAPATPSSKE 1578
                TL++  T A+ +P  A    +P + T         +P   TP    EA    ++  
Sbjct: 3424 VDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPV 3483

Query: 1579 ASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP----PAVTPPSPEKGPATPAPK 1634
             +S P  T S    +P+  E+   P  T+    E  TP    P  T P      +T +  
Sbjct: 3484 DTSTPVTTSSPTNSSPTTAEVTSMPTSTAG---EGSTPLTNMPVSTTPVASSEASTLSTT 3540

Query: 1635 GTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTP 1694
               ++  VT SS   S  +   VT    +T  + S  L        L    V  +  STP
Sbjct: 3541 PVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTM----LLSSTYVTSSEASTP 3596

Query: 1695 IITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDA 1754
               +  R  P T  + + S P  P+      S  P     P  ++PV   S   ++   A
Sbjct: 3597 STPSVDRSTPVTTSTQSNSTPTPPEVITLPMST-PSEVSTPLTIMPVSTTSVTISEAGTA 3655

Query: 1755 SHSPKGPLAP-------------PE---------SKASTPLTAAAFEKVLPKPESASVSA 1792
            S  P     P             PE         S+ STPLT              S  +
Sbjct: 3656 STLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLS 3715

Query: 1793 APSPPVSLPLAPS 1805
             PS   S P+  S
Sbjct: 3716 TPSVVTSTPVTTS 3728



 Score =  240 bits (612), Expect = 1e-62
 Identities = 416/1778 (23%), Positives = 661/1778 (37%), Gaps = 227/1778 (12%)

Query: 5    ATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQA 64
            +T    +TE       AE  V+P+S+A   +  L     +  P  SP       +  +  
Sbjct: 2484 STPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSN 2543

Query: 65   SPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIA 124
            SP  + + I+S+        S+ GT++P  T  E  T L ++   P+S   LA +    A
Sbjct: 2544 SPVVTSTEISSSAT------SAEGTSMPTSTYSEGSTPLRSM---PVSTKPLASSE---A 2591

Query: 125  PTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEP 184
             TL  TP  ++ + +      S   ++A   ++  S PS       S++  + P+A SE 
Sbjct: 2592 STLSTTPVDTS-IPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEA 2650

Query: 185  KTNLNKVPSE---VVPNPKGTPSPPCIV------STVPYHCVTPMASI--------QSGV 227
             T L+  P +   +V    GT S P         ++ P    TP+ +I         S  
Sbjct: 2651 ST-LSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEA 2709

Query: 228  ASLPQT-----TPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKG------PVSPPAAL 276
            ++L  T     TP TT A AS        +S+ IS  + GS  L        PV+   A 
Sbjct: 2710 STLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEAS 2769

Query: 277  SLSTQ----SLPVVTSSQKTAGPNTPP--DFPISLGSHLA-PLHQSSFGSVQLLGQTGPS 329
            ++ST     S+PV TS++ ++ P T      P S  S  + PL         +      +
Sbjct: 2770 TVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGT 2829

Query: 330  ALSDPTVKTISVDHSSTGASYPSQ-RSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTI 388
              + P   +  V  S+  +S P+    ++ P+ + +E      +      P      ST+
Sbjct: 2830 LSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTL 2889

Query: 389  SSITCSPSGSLNVATSFSLSPTTS------LILKSSPNATYHYPLVAQMPV-----SSVG 437
            S+     S  +  +T  S SPTT+      +   S  +      LV+ +PV     S++ 
Sbjct: 2890 STTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLS 2949

Query: 438  TTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQV 497
            TTP+    P T +A  +++   A   S P+S+ P     P +  ++   PVA  E ST  
Sbjct: 2950 TTPVDTRTPVTTSAEASSSPTTAEGTSMPIST-PGERRTPLTSMSVSTMPVASSEAST-- 3006

Query: 498  ATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGA--PFSPAQAGLTTKK 555
                             L   P+       T  +  + P + EG   P S    G T   
Sbjct: 3007 -----------------LSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPL- 3048

Query: 556  DPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVN 615
              T +P V   P   P   + S++P    SP  T  + S         PA   + P+   
Sbjct: 3049 --TSIP-VSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPT-----PAEGTSMPISTY 3100

Query: 616  SSASVIKTDSYAGPDSAGPLLKSSL----ITPTVAAFPLESADPAGVAPTTAKGTSTYTT 671
            S  S   T     P S  P+  S++     TP   + P+ ++  A  +PTT++GTS  T+
Sbjct: 3101 SEGSTPLTGV---PVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTS 3157

Query: 672  TASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPE-- 729
            T S   EG+        P+    ++T+ +V  +SE+  ++ +P +T  P+ T   A    
Sbjct: 3158 TPS---EGST-------PLTYMPVSTMLVV--SSEDSTLSATPVDTSTPVTTSTEATSST 3205

Query: 730  ------IPKSVPSP------SLPPAGTPPGTKKVDGISHT--------------SALAPV 763
                  IP S PS       S+P + TP  + +   +S T              S+  P 
Sbjct: 3206 TAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPT 3265

Query: 764  A---SSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTP 820
            A   S P   P+E  G++   S   + T +A S +    +    T  P T    A    P
Sbjct: 3266 AEGTSMPTSTPSE--GSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPP 3323

Query: 821  IGN-LSSPVSPVEASFLPENSLSFQGSK--DSPATTHSPTP---PSPKGAPTPSAVTPLS 874
            I +  S P S       P  ++SF  +    S A+T S TP    +P    T ++++P +
Sbjct: 3324 IADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTT 3383

Query: 875  PKGVTLP---PKETPTP------SVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATP 925
             +G ++P   P E  TP      S   +   +    +  P  +  L  TS+    +    
Sbjct: 3384 AEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIA 3443

Query: 926  APKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGA 985
                +P S + +G+ TP +  P S     ++ +   + TP   + P     P   SP  A
Sbjct: 3444 EGTSLPTSTTSEGS-TPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTA 3502

Query: 986  PTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKG 1045
                 + P S  G  +TP       P + TP +   +   +  P  ++T   ++  +   
Sbjct: 3503 EV--TSMPTSTAGEGSTPLTN---MPVSTTPVASSEASTLSTTPVDSNTFVTSSSQA-SS 3556

Query: 1046 SPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP---TPPAATPPSPKGGPATPSPKGA 1102
            SPA   +     TT   + PS      T  L  +    +  A+TP +P    +TP     
Sbjct: 3557 SPATLQV-----TTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTST 3611

Query: 1103 PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1162
                  TPP               T P +TP      L   P      T +    +    
Sbjct: 3612 QSNSTPTPPE------------VITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLP 3659

Query: 1163 LATPPPKGAPTTPAATPPSPKGG---LATPSPKGAPTTP---AATPPSPKGGLATPSPKG 1216
            + T  P    T  +++P +P+G    + TPS    P T    + T  +   G    +P  
Sbjct: 3660 VDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSV 3719

Query: 1217 APTTPAATPPSPKGGLATPSPKGAPTTPAATPP---SPKGGP---ATPPPKGAPTPPAAT 1270
              +TP  T        AT       TT + + P   S  G     +T P    P     +
Sbjct: 3720 VTSTPVTTSTEAISSSATLDS----TTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPS 3775

Query: 1271 PPSLKGGLA-TPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPP 1329
             PS+   ++ T   +G+ +P  +   +      TS      T    +P S         P
Sbjct: 3776 IPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMS------P 3829

Query: 1330 KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS-KEGPTPPAATPSHKGGPAMTPPS 1388
              A T    TPP    TP L +T   S   P   ++ +   T   +TP      + T P+
Sbjct: 3830 SEAST--LSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPT 3887

Query: 1389 PKRGPAIPSPKGDPTSPAVIPLSPKKA-PATPVTREGAATPSKGDLTPPAVTPVSLKKAP 1447
               G +I S     TS    P +   + P  PV    + +      TP   T + +   P
Sbjct: 3888 SFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPG--TTIFIPSTP 3945

Query: 1448 ATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSS-SPKKAPATPAPMGAPTLP 1506
             TS+       P++ G  + P +T      P       T+S S  K   TPA   A  L 
Sbjct: 3946 VTSST--ADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLT 4003

Query: 1507 AVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPT 1566
             V  S+    P T S  R      +TL +  TP T     ++    +T  S    P+  T
Sbjct: 4004 YVTMSTAPSTPRTTS--RGCTTSASTLSATSTPHT---STSVTTRPVTPSSESSRPSTIT 4058

Query: 1567 PKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEK 1626
                P T     +S+PP  T S      +P+ +      T PS +    P   T   P  
Sbjct: 4059 SHTIPPTFPPAHSSTPP--TTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTN 4116

Query: 1627 GPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGAT 1664
                  P  TPT P  T +   D   + AS  CK G T
Sbjct: 4117 TTIKSNPTSTPTVPRTT-TCFGDGCQNTAS-RCKNGGT 4152



 Score =  236 bits (603), Expect = 1e-61
 Identities = 429/1910 (22%), Positives = 679/1910 (35%), Gaps = 253/1910 (13%)

Query: 176  SAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVA---SLPQ 232
            S  + PS  +   +    E    P  TPS   I ST+ +    P+ S ++  +    +  
Sbjct: 125  STTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDM 184

Query: 233  TTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKG------PVSPPAALSLSTQ----S 282
            +TP TT   AS        +++  S  + GS  L         V+   A++L T     S
Sbjct: 185  STPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEIS 244

Query: 283  LPVVTSSQKTAGPNTPPDFPISLGS---HLAPLHQSSFGSVQLLGQTGPSALSDPTVKTI 339
             PV  S+Q ++ P T     +S  +      PL +     + ++     +  + P    I
Sbjct: 245  TPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNI 304

Query: 340  SVDHSSTGASYP--SQRSVIPPLPSRNEVVPAT---VAAFPVVAPSVDK------GPSTI 388
             V  S+  +S P  ++ + IP         P T    +  PV    +          ST+
Sbjct: 305  PVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTL 364

Query: 389  SSITCSPSGSLNVATSFSLSPTTSLILKSSP--NATYHYPLVAQMPVSSVGTTPL----V 442
             + +  PS     A + S+  T++L   S+P  N      LVA    S+  T P+     
Sbjct: 365  VTTSTEPSSLPTTAEATSML-TSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTF 423

Query: 443  VTNPCTIAAAPTTTFEVATCV------SPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQ 496
            VT     +++PTT  + +         S P++S P+S     S  A  ++   P +  TQ
Sbjct: 424  VTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLS-TTPVDSKTQ 482

Query: 497  VATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAG-LTTKK 555
            V T+     SPP     ++ ++P+S     P++        S+   P + ++A  L+T  
Sbjct: 483  VTTSTEASSSPP---TAEVNSMPTST----PSEGSTPLTSMSVSTMPVASSEASTLSTTP 535

Query: 556  DPTVLPLVQAAPKNSPSF--QSTSSSPEIPLSPEATLAKKSLGEPLPIGKPAS-SMTSPL 612
              T  P+  ++  +S S   + TS     P      L    +   L +   AS + T+P 
Sbjct: 536  VDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPA 595

Query: 613  GVNSSASVIKTDSYAGPDSAG-------------PLLKSSLITPTVAAFPLESADPAGVA 659
              N+  +     S +   + G              +   S+ T  VA+    +     V 
Sbjct: 596  DSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVD 655

Query: 660  PTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPT---ASENCPVAPSPQN 716
              T   TST  T++S   EGT S+    +      LT++P+  T   +SE   ++ +P +
Sbjct: 656  SNTPVTTSTEATSSSTTAEGT-SMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVD 714

Query: 717  TCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDG--ISHTSALAPVASSPKECPTED 774
            T  P+ T   A   P +    S+P +    G+  +    +S T   +  AS+    P + 
Sbjct: 715  TSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDT 774

Query: 775  S---GASATASSKGTLTYLADSP-------SPLGVSVSPQTKRPPTKKGSAGPDTPIGNL 824
            S     S  AS   T T     P       SPL  S+        + + S    TP+ + 
Sbjct: 775  STHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDS- 833

Query: 825  SSPV---SPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLP 881
            +SPV   + V +S  P    S   S  S   T   + P        SA++ LS   V   
Sbjct: 834  NSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTS 893

Query: 882  PKETPTPSVVNLPFPKEG----PATPAPKQAPALSM-------TSSSPKKARATPAPKGI 930
               T +    + P   EG     +TP     P  SM        SS  +   ATP     
Sbjct: 894  TPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTST 953

Query: 931  PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA 990
            P + S +   +P  A   S      T +P    TP  +TP S            +     
Sbjct: 954  PVTTSTEATSSPTTAEGTS----IPTSTPSEGTTPLTSTPVS------HTLVANSEASTL 1003

Query: 991  ATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAAT 1050
            +T P     P T S     T  +  PP+ +G+   T  P   STP    P S       T
Sbjct: 1004 STTPVDSNTPLTTS-----TEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVS-------T 1051

Query: 1051 PLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA----TPPSPKGGPATPSPKGAPMPP 1106
             +   + T+  +T P+    P T   + + +   A     P S     +TP     P+  
Sbjct: 1052 TMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPL-TSVPVST 1110

Query: 1107 AATPPSPKGGLATPPHKGA----PTTPAATPPSPKGGLATP-PPKGAPTTPAATPPSPKG 1161
                 S    L+T P   +     +T A++ P+   G + P  P    TTP A+ P    
Sbjct: 1111 RLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVS-- 1168

Query: 1162 GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT- 1220
               T        T + TP   K  +AT +   +P   A     P    +TP  +  P T 
Sbjct: 1169 --TTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMP---TSTPGERSTPLTS 1223

Query: 1221 -PAATPPSPKGGLATPSPKGAPT-TPAATPPSPKGGPATPPPKGAPTPPAA------TPP 1272
             P    P      +T S     T TP  T       P T      PT   +      T  
Sbjct: 1224 MPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSI 1283

Query: 1273 SLKGGLATPPHKGAPNPAVVTPPSPKGGPATS-PPKGAPTPPAATP-PSPKGSPGTPPPK 1330
             +   L T P     +  + TP   KG   TS     +PTP   T  P+   S G  P  
Sbjct: 1284 PVSTTLVTSPE---ASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLT 1340

Query: 1331 GAPTPPAVTPPSPKGTPTLPATTPSSKGGPTT--------PSSKEGPTPPAATPSHKGGP 1382
              P    +   S     ++ +TTP     P T        P++ EG + P + PS    P
Sbjct: 1341 SIPVNTTLVASS---AISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTP 1397

Query: 1383 AMTPP---SPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREG----AATPSKGDLTP 1435
              + P   +P       +    P   +    +  +A ++P T EG     +TPS+G  TP
Sbjct: 1398 LTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGK-TP 1456

Query: 1436 PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPA 1495
                PVS     A S       TP     P + +    S   P     +A S+  + + A
Sbjct: 1457 LKSIPVS-NTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTA 1515

Query: 1496 -TPAPMGAPTLPA----------VIPSSP----KEVPATPSSRRDPIAPTATLLSKKTPA 1540
             T  P+   T+ +           + S+P     +  ++P++       T+T     TP 
Sbjct: 1516 LTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPL 1575

Query: 1541 TLAPKEALIPPA------MTVPSPKKTP------------------AIPTPKEAPATPSS 1576
            T  P   ++  +       T P   KT                    I TP E     +S
Sbjct: 1576 TSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTS 1635

Query: 1577 KEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT--PPSPEKGPATPAPK 1634
               S+ P  +P     + +P +    P +TS     +PTP   T  P S      TP   
Sbjct: 1636 IPVSTTPVASPEASTLSTTPVD-SNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTS 1694

Query: 1635 GTPTSPPVTPSSLKDSPTSPAS-----VTCKMGATVPQASKGL-----PAKKGPTALKEV 1684
             T  + PV  S++    T+P        T     + P  S+G         +G T L  +
Sbjct: 1695 ITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSI 1754

Query: 1685 LVAPAP---------ESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVA- 1734
             V+  P          +TPI T+     P T  + ATS      P+   G+  P ST++ 
Sbjct: 1755 PVSTTPVLSSEASTLSATPIDTST----PVTTSTEATS-----SPTTAEGTSIPTSTLSE 1805

Query: 1735 ---PAPLLPVQKDSSKTAKGKDASHSP---KGPLAPPESKASTPLTAAAFEKVLPKPESA 1788
               P    PV       ++    S +P     P+    + +S+P  A         P   
Sbjct: 1806 GMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEG 1865

Query: 1789 SVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEP 1848
            S +    P  +  +A S   TL      + S+P       S     AD   +    P E 
Sbjct: 1866 STALTSIPVSTTTVASSETNTLSTTPA-VTSTPVTTYAQVSSSPTTADGSSMPTSTPRE- 1923

Query: 1849 ISGGVPFQSVLVNMPTPKSAGI---PVPTPSAKQPVTKNNKGSGTESDSD 1895
              G  P  S+ V+  T  S+ I          + PVT  ++ S + + +D
Sbjct: 1924 --GRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTAD 1971



 Score =  207 bits (528), Expect = 7e-53
 Identities = 373/1753 (21%), Positives = 608/1753 (34%), Gaps = 252/1753 (14%)

Query: 387  TISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNP 446
            T S+    P   L+ +T+  ++   S +   +P             VSS   TP      
Sbjct: 71   TTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPG------------VSSTRMTPTESRTT 118

Query: 447  CTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVS 506
                +  TT F        P S+   S+  PT+P    +    P E S  +++T+    +
Sbjct: 119  SESTSDSTTLF--------PSSTEDTSS--PTTPEGTDVPMSTPSEES--ISSTMAFVST 166

Query: 507  PPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAA 566
             PLP  E   +L   V +  P     Q   +S    P S      T  +  T L  + A+
Sbjct: 167  APLPSFEAYTSLTYKVDMSTPLTTSTQA--SSSPTTPESTTIPKSTNSEGSTPLTSMPAS 224

Query: 567  PKNSPSFQS-TSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDS 625
                 S ++ T  +  + +S   T++ ++   P     P+ S ++P G ++  + +    
Sbjct: 225  TMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSV 284

Query: 626  YAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAP 685
                 S    L +   TP     P+ ++  A  +PTTA+GTS  T+T +       S   
Sbjct: 285  MLVVSSEASTLST---TPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPA 341

Query: 686  KNHPVKEGTLTTLPLVPTASE---NCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPA 742
               PV    ++TL + P  +         PS   T A   +++ +     S P  ++P +
Sbjct: 342  STMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVS 401

Query: 743  --------GTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGT--LTYLAD 792
                     +   T  VD  +  +  +  +SSP     ED+  + +  S+G+  LT +  
Sbjct: 402  TILVASSEASTTSTIPVDSKTFVTTASEASSSP--TTAEDTSIATSTPSEGSTPLTSMPV 459

Query: 793  SPSPLGVS---------VSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASF-LPENSLS 842
            S +P+  S         V  +T+   + + S+ P T   N     +P E S  L   S+S
Sbjct: 460  STTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVS 519

Query: 843  FQGSKDSPATTHSPTP---PSPKGAPTPSAVTPLSPKGVTLP---PKETPTPSVVNLPF- 895
                  S A+T S TP    +P    + ++ +  +P+G ++P   P E  TP + N+P  
Sbjct: 520  TMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTP-LTNMPVS 578

Query: 896  ------PKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASP-SPKG---------- 938
                   +    +  P  +     TSS    +  T     +P S  S +G          
Sbjct: 579  TRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVST 638

Query: 939  -----------APTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGG-PATPSPKGAP 986
                       + TP  +  P      AT S   A      T    +G  P T  P    
Sbjct: 639  TLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTT 698

Query: 987  TPPAATPPSPKGGPA-TPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP----- 1040
               ++   +    P  T +P    T  + +P +  G+   T  P   STP  + P     
Sbjct: 699  LVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTL 758

Query: 1041 --PSPKGSPAATPLPKG-----------APTTPAAT---LPSP-KGGPATPSLKGAPTPP 1083
               S   + + TPL              +PTT   T   + +P +G P   S+  + TP 
Sbjct: 759  LTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITP- 817

Query: 1084 AATPPSPKGGPATPSPKGAPMPPA---ATPPSPKGGLATP---------PHKGAPTTPAA 1131
              T P       TP    +P+  +   ++ P+P  G + P         P    P +   
Sbjct: 818  -VTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTL 876

Query: 1132 TPPSPKGGLATPP------------PKGAPTTPAAT--PPSPKGGLATPPPKGAPTTPAA 1177
               S    L+T P             + +PTT   T  P S  G  +TP      +T   
Sbjct: 877  VATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPV 936

Query: 1178 TPPSPKGGLATPSPKGAP-TTPAATPPSPKGGLATPSPKGAP---TTPAATPPSPKGGLA 1233
                 +   ATP     P TT      SP     T  P   P   TTP  + P     +A
Sbjct: 937  VSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVA 996

Query: 1234 TPSPKGAPTTP--AATPPSPKGGPATPPPKGAPTP-PAATP-----PSLKGGLATPPHKG 1285
                    TTP  + TP +     ++PPP    T  P +TP     P  +  ++T     
Sbjct: 997  NSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVAS 1056

Query: 1286 APNPAVVTPPSPKGGPATS---PPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPS 1342
            +    + T P+    P T+       + T    + P+   S G+ P    P    +   S
Sbjct: 1057 SETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSS 1116

Query: 1343 --------------PKGTPTLPATTPSSKGGPTTPSS--KEGPTPPAATP--------SH 1378
                          P  T T  +++P++  G + P+S   EG TP A+ P        S 
Sbjct: 1117 EASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSE 1176

Query: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA-------------TPVTREGA 1425
                + TP   K   A  +    P   A +   P   P              TPV    A
Sbjct: 1177 ANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEA 1236

Query: 1426 ATPSKG--DLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ 1483
            +T S    D + P  T      +P T+     P + +S+G   L ++        P    
Sbjct: 1237 STLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSI--------PVSTT 1288

Query: 1484 VATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLA 1543
            + TS        TP     P +      +  EV ++P+       PT+T    +TP T  
Sbjct: 1289 LVTSPEASTLLTTPVDTKGPVV------TSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSI 1342

Query: 1544 P------KEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK 1597
            P        + I    T P    TP + T  EA ++P++ E +S P   PS      +  
Sbjct: 1343 PVNTTLVASSAISILSTTPVDNSTP-VTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSI 1401

Query: 1598 ELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPK-----GTPTSPPVT-PSSLKDSP 1651
             +   P V+S +   + TP   + P      AT +P        PTS P    + LK  P
Sbjct: 1402 PVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIP 1461

Query: 1652 TSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAP---ESTPIITAPTRKGPQTKK 1708
             S   V     +T+       P       +    V+ +P   E T I  +   +G     
Sbjct: 1462 VSNTPVANSEASTLSTT----PVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALT 1517

Query: 1709 SSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESK 1768
            S   S          + S  P  T  P         S  TA G     S         S+
Sbjct: 1518 SIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTS-------TYSE 1570

Query: 1769 ASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESP 1828
             STPLT+     +L     A+            L+ +P+ +         +S     E  
Sbjct: 1571 GSTPLTSLPVSTMLVVSSEANT-----------LSTTPIDSKTQVTASTEASSSTTAEGS 1619

Query: 1829 SKPLA-PADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKG 1887
            S  ++ P++   LL  IP        P  S L   P   ++ +   T  +  P       
Sbjct: 1620 SMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTS 1679

Query: 1888 SGTESDSDESVP--ELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSK 1945
              T + ++   P   +  + +  A++  + L+     +  PV+ + ++RS     +  S 
Sbjct: 1680 MPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSM 1739

Query: 1946 LGLRQVTGVTRVT 1958
                   G T +T
Sbjct: 1740 PNSTPSEGTTPLT 1752


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  243 bits (619), Expect = 2e-63
 Identities = 318/1203 (26%), Positives = 388/1203 (32%), Gaps = 198/1203 (16%)

Query: 705  SENCPVAPSPQNTCAPLA---------TLVLAPEIPKSVPSPSLP--PAGTPPGTKKVDG 753
            ++NCP A  P+  C P+                E PK    P  P  PAG PPG   + G
Sbjct: 78   TKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAG-PPGRDGIPG 136

Query: 754  ISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKG 813
                    P    P   P          +    L+Y  D  S  G+SV           G
Sbjct: 137  -------QPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISV----------PG 179

Query: 814  SAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTP------ 867
              GP  P G    P +P            FQG    P    +  P  P+G P P      
Sbjct: 180  PMGPSGPRGLPGPPGAP--------GPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGD 231

Query: 868  --SAVTPLSP--KGVTLPPKETPTPSVVNLPFPK-----------EGPATPA-PKQAPAL 911
               A  P  P  +G   P      P    LP  K           +G A PA PK  P  
Sbjct: 232  DGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGS 291

Query: 912  SMTSSSPKK--ARATPAPKGIPASPSPKGAPTPPAAT----PPSPKGGPATPS-PKWAPT 964
               + +P +   R  P  +G P +P P GA     AT    PP P G    P  P     
Sbjct: 292  PGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGA 351

Query: 965  PPAATPPSPKGGPATPSPKGAPTPP----AATP---------PSPKGGPATPSPKGAPTP 1011
               A P  P+G       +G P PP    AA P         P  KG    P   GAP  
Sbjct: 352  KGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGF 411

Query: 1012 PAVTPPSPKGSPAATPFPKGASTPPAAT----------PPSPKG-----SPAATPLPKGA 1056
            P    PS    P   P PKG S  P A            P P G      PA     +GA
Sbjct: 412  PGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGA 471

Query: 1057 PTTPAAT-LPSPKGGPATPSLKGAPTPPAAT----PPSPKGGPATPSPKGAP----MPPA 1107
               P  T LP P G    P  +G P          P   +G P    PKG+P     P  
Sbjct: 472  RGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGE 531

Query: 1108 ATPPSPKGGLATPPHKGAPTTPAAT-PPSPKGGLATPPPKGAPTTPAATP----PSPKGG 1162
            A  P  KG   +P   G+P     T PP P G    P P G P           P PKG 
Sbjct: 532  AGLPGAKGLTGSP---GSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGA 588

Query: 1163 LATP---PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT-----------------P 1202
               P     +G P  P A  P+ K G A       P  PA                   P
Sbjct: 589  AGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGP 648

Query: 1203 PSPKGGLATPSPKGAPTTPAATPPS-PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPK 1261
              P G    P  +G P    A  PS  +G    P  +G    P   P  P+G    P   
Sbjct: 649  AGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPG--PAGPRGANGAPGND 706

Query: 1262 GAPTPPAATPPSLKGGLATPPHKGAPNP-AVVTPPSPKGGPATSPPKGAPTPPAATPPSP 1320
            GA     A  P   G    P  +G P        P PKG    + PKGA   P       
Sbjct: 707  GAKGDAGA--PGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRG 764

Query: 1321 KGSP-GTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKG--GPTTPSSKEGPTPPAATPS 1377
               P G P P GAP     + PS    PT     P  +G  GP  P+   GP      P 
Sbjct: 765  LTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPG 824

Query: 1378 HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATP-------SK 1430
             KG P         GP  P P G    P   P+    AP     R  A  P       + 
Sbjct: 825  AKGEPGDAGAKGDAGP--PGPAGPAGPPG--PIGNVGAPGAKGARGSAGPPGATGFPGAA 880

Query: 1431 GDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPT--LPAVTPPSPKEPPAPKQVATSS 1488
            G + PP  +  +    P   A K G   P  +  P      V PP P  P   K    + 
Sbjct: 881  GRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGAD 940

Query: 1489 SPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548
             P  AP TP P G      V+      +P     R  P  P  +    K   + A  E  
Sbjct: 941  GPAGAPGTPGPQGIAGQRGVV-----GLPGQRGERGFPGLPGPSGEPGKQGPSGASGERG 995

Query: 1549 IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP 1608
             P  M  P     P     + AP    S      P       +  P+      PP   +P
Sbjct: 996  PPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAG-----PPG--AP 1048

Query: 1609 SPKEAPTPPAVTPPSPEKGPATPA-PKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ 1667
                AP P      S ++G   PA P G     PV P   +  P  P       G T  Q
Sbjct: 1049 GAPGAPGPVGPAGKSGDRGETGPAGPAG-----PVGPVGAR-GPAGPQGPRGDKGETGEQ 1102

Query: 1668 ASKGLPAKKGPTALKEVLVAPAPESTPIITAPT----RKGPQTKKSSATSPPICPDPSAK 1723
              +G+   +G + L+     P P  +P    P+      GP+    SA +    P     
Sbjct: 1103 GDRGIKGHRGFSGLQG---PPGPPGSPGEQGPSGASGPAGPRGPPGSAGA----PGKDGL 1155

Query: 1724 NGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFE-KVL 1782
            NG  GP+    P              +G+     P GP  PP         +A F+   L
Sbjct: 1156 NGLPGPIGPPGP--------------RGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFL 1201

Query: 1783 PKP 1785
            P+P
Sbjct: 1202 PQP 1204



 Score =  231 bits (589), Expect = 6e-60
 Identities = 311/1160 (26%), Positives = 373/1160 (32%), Gaps = 238/1160 (20%)

Query: 850  PATTHSPTPPSPKGAPTPSAVT-PLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAP--- 905
            P  + SPT     G   P   T P  P+G   PP     P    LP P   P  P P   
Sbjct: 96   PDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGL 155

Query: 906  --KQAPALSMTSSSPKKAR-ATPAPKGIPASPSPKGAPTPPAATPP----SPKGGPATP- 957
                AP LS           + P P G      P+G P PP A  P     P G P  P 
Sbjct: 156  GGNFAPQLSYGYDEKSTGGISVPGPMG---PSGPRGLPGPPGAPGPQGFQGPPGEPGEPG 212

Query: 958  -----SPKWAPTPPAAT----------------PPSPKGGPATPSPKGAP---------- 986
                  P+  P PP                   PP P+G    P   G P          
Sbjct: 213  ASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSG 272

Query: 987  ---TPPAATPPSPKGGPATPSPKGAPTPPAVTP-PSPKGSPAATPFPKGA----STPPAA 1038
                   A P  PKG P +P   GAP        P  +G P A P P GA        AA
Sbjct: 273  LDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGA-PGPAGARGNDGATGAA 331

Query: 1039 TPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPP----AATP------- 1087
             PP P G       P        A    P+G      ++G P PP    AA P       
Sbjct: 332  GPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGAD 391

Query: 1088 --PSPKGGPATPSPKGAPMPPAAT----------PPSPKGGLATPPHKGAP-TTPAATPP 1134
              P  KG    P   GAP  P A           PP PKG    P   G+   T A   P
Sbjct: 392  GQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEP 451

Query: 1135 SPKGGLATPPP------KGAPTTPAATP-PSPKGGLATPPPKGAP-TTPAATPPSPKGGL 1186
             P G    P P      +GA   P  T  P P G    P  +G P     A P  P G  
Sbjct: 452  GPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGER 511

Query: 1187 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT-------PPSPKGGLATPSPKG 1239
             +P P G   +P       + GL  P  KG   +P +        PP P G    P P G
Sbjct: 512  GSPGPAGPKGSPGEAGRPGEAGL--PGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPG 569

Query: 1240 APTTPAATP----PSPKGG---PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV 1292
             P           P PKG    P     +G P PP A  P+ K G A    +G P PA  
Sbjct: 570  PPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGA--QGPPGPAGP 627

Query: 1293 TPPSPKGGPATSPP-KGAPTPPAATPPSPKGSP---GTPPPKGAPTPPAVTP----PSPK 1344
                 + GPA SP  +G P P  A PP   G P   G P   GAP P         P  +
Sbjct: 628  AGERGEQGPAGSPGFQGLPGP--AGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGER 685

Query: 1345 GT--PTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPA-IPSPKGD 1401
            G   P  PA    + G P    +K     P A P  +G P +     +RG A +P PKGD
Sbjct: 686  GVQGPPGPAGPRGANGAPGNDGAKGDAGAPGA-PGSQGAPGLQGMPGERGAAGLPGPKGD 744

Query: 1402 --------------------------PTSPAVIP----LSPKKAPATPVTREGAATPSKG 1431
                                      P  PA  P     S    PA P    G A   +G
Sbjct: 745  RGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARG-APGDRG 803

Query: 1432 DLTPPAVTPVSLKKAPATS---APKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSS 1488
            +  PP   P      P        KG P    +KGD   P   P  P  PP P     + 
Sbjct: 804  EPGPPG--PAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPG--PAGPAGPPGPIGNVGAP 859

Query: 1489 SPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSK-------KTPAT 1541
              K A  +  P GA   P    ++ +  P  PS    P  P      +       +T   
Sbjct: 860  GAKGARGSAGPPGATGFPG---AAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPA 916

Query: 1542 LAPKEALIPPAMTVPSPKK-TPAIPTPKEAPATPSSKEASSPPAVT-------PSTYKGA 1593
              P E + PP    P+ +K +P    P  AP TP  +  +    V           + G 
Sbjct: 917  GRPGE-VGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGL 975

Query: 1594 PSPKELLIPPAVTSPS-------PKEAPTPPAVTPPSPEKG-PATPAPKGTP---TSPPV 1642
            P P      P    PS       P     PP +  P  E G    P  +G+P    SP  
Sbjct: 976  PGPSG---EPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGA 1032

Query: 1643 TPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPI--ITAPT 1700
                 +  P  P       GA  P    G    +G T        PA  + P+  + A  
Sbjct: 1033 KGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGET-------GPAGPAGPVGPVGARG 1085

Query: 1701 RKGPQTKKS-------------------SATSPPICPDPSAKNGSKGPLSTVAPAPLLPV 1741
              GPQ  +                    S    P  P P    G +GP     PA   P 
Sbjct: 1086 PAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGP--PGPPGSPGEQGPSGASGPAG--PR 1141

Query: 1742 QKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLP 1801
                S  A GKD  +   GP+ PP  +  T                A     P PP   P
Sbjct: 1142 GPPGSAGAPGKDGLNGLPGPIGPPGPRGRT--------------GDAGPVGPPGPPG--P 1185

Query: 1802 LAPSPVPTLPPKQQFLPSSP 1821
              P   P+      FLP  P
Sbjct: 1186 PGPPGPPSAGFDFSFLPQPP 1205



 Score =  216 bits (549), Expect = 2e-55
 Identities = 303/1162 (26%), Positives = 371/1162 (31%), Gaps = 204/1162 (17%)

Query: 918  PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGP 977
            P+     P   GIP  P   G P PP    P   GG   P   +     +    S  G  
Sbjct: 122  PRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPM 181

Query: 978  ATPSPKGAPTPPAAT-------PPSPKGGPATPSPKGAPTPPAVTPPSPKG--SPAATPF 1028
                P+G P PP A        PP   G P    P G   PP   PP   G    A  P 
Sbjct: 182  GPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPG--PPGKNGDDGEAGKPG 239

Query: 1029 PKGASTPPAATPPSPKGSPAATPLP--------KGAPTTPAATLPS-PKGGPATPSLKGA 1079
              G   PP   P   +G P    LP         G         P+ PKG P +P   GA
Sbjct: 240  RPGERGPPG--PQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGA 297

Query: 1080 PTPPAATP-PSPKGGPATPSPKGAPMPPAAT----PPSPKGGLATPPHKGAPTTPA-ATP 1133
            P        P  +G P  P P GA     AT    PP P G    P   GA      A P
Sbjct: 298  PGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGP 357

Query: 1134 PSPKG--------GLATPPPKGAPTTPAATP-----PSPKGGLATPPPKGAPTTPAATPP 1180
              P+G        G   PP       PA  P     P  KG    P   GAP  P A  P
Sbjct: 358  QGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGP 417

Query: 1181 S-PKGGLATPSPKGAPTTPAAT----------PPSPKGGLATPSP------KGAPTTPAA 1223
            S P+G    P PKG    P A            P P G    P P      +GA   P  
Sbjct: 418  SGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGP 477

Query: 1224 TP-PSPKGGLATPSPKGAPTTPAAT----PPSPKGGPATPPPKGAP----TPPAATPPSL 1274
            T  P P G    P  +G P          P   +G P    PKG+P     P  A  P  
Sbjct: 478  TGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGA 537

Query: 1275 KGGLATPPHKGAPNPAVVT-PPSPKGGPATSPPKGAPTPPAATP-------PSPKGS--- 1323
            KG   +P   G+P P   T PP P G        G P PP A         P PKG+   
Sbjct: 538  KGLTGSP---GSPGPDGKTGPPGPAGQDGR---PGPPGPPGARGQAGVMGFPGPKGAAGE 591

Query: 1324 PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG--G 1381
            PG    +G P PP    P+ K         P    GP  P+ + G   PA +P  +G  G
Sbjct: 592  PGKAGERGVPGPPGAVGPAGKDGEAGAQGPP----GPAGPAGERGEQGPAGSPGFQGLPG 647

Query: 1382 PAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPV 1441
            PA  PP     P      GD  +P   P   +     P  R G   P      P    P 
Sbjct: 648  PA-GPPGEAGKPGEQGVPGDLGAPG--PSGARGERGFPGER-GVQGP------PGPAGPR 697

Query: 1442 SLKKAPATSAPK---GGPATPSSKGDPTLPAVTPPSPKEP---PAPKQVATSSSPKKAPA 1495
                AP     K   G P  P S+G P L  +  P  +     P PK     + PK A  
Sbjct: 698  GANGAPGNDGAKGDAGAPGAPGSQGAPGLQGM--PGERGAAGLPGPKGDRGDAGPKGADG 755

Query: 1496 TPAPMGAPTLPAVI-------------------PSSPKEVPATPSSRRDPIAPTATLL-- 1534
            +P   G   L   I                   P+ P      P  R +P  P       
Sbjct: 756  SPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAG 815

Query: 1535 ---------SKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV 1585
                     +K  P     K    PP    P+    P       AP    ++ ++ PP  
Sbjct: 816  PPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPI--GNVGAPGAKGARGSAGPPGA 873

Query: 1586 T----PSTYKGAPSPKELLIPPAVTSPSPKE-----------APTPPAVTPPSP-----E 1625
            T     +   G P P     PP    P+ KE           A  P  V PP P     E
Sbjct: 874  TGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGE 933

Query: 1626 KG-PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEV 1684
            KG P    P G P +P     + +           + G        G P K+GP+     
Sbjct: 934  KGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGE 993

Query: 1685 LVAPAPESTPIITAPT-RKGPQTKKSSATSPPICPDPSAK--NGSKGPL-------STVA 1734
               P P   P +  P    G +    +  SP     P AK   G  GP        +  A
Sbjct: 994  RGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGA 1053

Query: 1735 PAPLLPVQKDSSKTAKGKDASHSP------KGPLAPPESKASTPLTAAAFEKVLPKPESA 1788
            P P+ P  K   +   G      P      +GP  P   +     T    ++ +      
Sbjct: 1054 PGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGF 1113

Query: 1789 SVSAAPSPPVSLPLAPSPV-------PTLPPKQQFLPSSPGL-VLESPSKPLAPADE-DE 1839
            S    P  P   P    P        P  PP     P   GL  L  P  P  P     +
Sbjct: 1114 SGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGD 1173

Query: 1840 LLPLIPPEPISGGVPFQSVLVNMPTPKSAGIP---VPTPSAKQPVTKNNKGSGTESDSDE 1896
              P+ PP P     P        P P SAG     +P P    P  K + G       D 
Sbjct: 1174 AGPVGPPGPPGPPGP--------PGPPSAGFDFSFLPQP----PQEKAHDGGRYYRADDA 1221

Query: 1897 SV---PELEEQDSTQATTQQAQ 1915
            +V    +LE   + ++ +QQ +
Sbjct: 1222 NVVRDRDLEVDTTLKSLSQQIE 1243



 Score =  157 bits (398), Expect = 8e-38
 Identities = 181/654 (27%), Positives = 218/654 (33%), Gaps = 111/654 (16%)

Query: 735  PSPSLPPAGT-----PPGTKKVDGISHTSALAPVASSPKECPTE-DSGASATASSKGTLT 788
            P P+  PAG      P G+    G+   +     A  P E     D GA   + ++G   
Sbjct: 622  PGPA-GPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERG 680

Query: 789  YLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKD 848
            +    P   GV   P    P    G+ G D   G+  +P +P              GS+ 
Sbjct: 681  F----PGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAP--------------GSQG 722

Query: 849  SPATTHSPTPPSPKGAPTPSAVT-PLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907
            +P     P      G P P        PKG    P +     +   P    GPA     +
Sbjct: 723  APGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTG-PIGPPGPAGAPGDK 781

Query: 908  APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT-PPSPKG-------------- 952
              +     + P  AR  P  +G P  P P G   PP A   P  KG              
Sbjct: 782  GESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPP 841

Query: 953  GPATPSPKWAPTPPAATPPSPKGGPATPSPKGA---PTPPAAT----------PPSPKGG 999
            GPA P+           PP P G    P  KGA     PP AT          PP P G 
Sbjct: 842  GPAGPA----------GPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGN 891

Query: 1000 PATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTT 1059
               P P G         P  +  PA  P   G   PP   P   KGSP A   P GAP T
Sbjct: 892  AGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPG--PAGEKGSPGADG-PAGAPGT 948

Query: 1060 PAAT-LPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLA 1118
            P    +   +G    P  +G    P    P P G P    P GA       PP P G   
Sbjct: 949  PGPQGIAGQRGVVGLPGQRGERGFPGL--PGPSGEPGKQGPSGA--SGERGPPGPMG--- 1001

Query: 1119 TPPHKGAPTTPAATPPSPKGGLATPPPKGAP---TTPAATPPSPKGGLATPPPKGAPTTP 1175
             PP         A PP   G    P  +G+P    +P A     + G A PP  GAP  P
Sbjct: 1002 -PP-------GLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPP--GAPGAP 1051

Query: 1176 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1235
             A  P    G +    +  P  PA  P  P G      P+G        P   KG     
Sbjct: 1052 GAPGPVGPAGKSGDRGETGPAGPAG-PVGPVGARGPAGPQG--------PRGDKGETGEQ 1102

Query: 1236 SPKGAP----TTPAATPPSPKGGPATPPPKGAPTPPAAT-PPSLKGGLATPPHKGAPNPA 1290
              +G       +    PP P G P    P GA  P     PP   G        G P P 
Sbjct: 1103 GDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGP- 1161

Query: 1291 VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPK 1344
             + PP P+G    + P G P PP   PP P G    PP  G        PP  K
Sbjct: 1162 -IGPPGPRGRTGDAGPVGPPGPPG--PPGPPG----PPSAGFDFSFLPQPPQEK 1208



 Score = 36.6 bits (83), Expect = 0.26
 Identities = 93/378 (24%), Positives = 112/378 (29%), Gaps = 86/378 (22%)

Query: 3   GEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGP---TLPPPCSPAPQQC--- 56
           GE     PA  +  P          +  A  +T + G PGP   T PP   PA Q     
Sbjct: 509 GERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPP--GPAGQDGRPG 566

Query: 57  ---PLSAANQASP--FPSPSTIASTPLE-----VPFPQSSSGTALPLGTA-------PEA 99
              P  A  QA    FP P   A  P +     VP P  + G A   G A       P  
Sbjct: 567 PPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAG 626

Query: 100 PTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSA-PLALVALAPHSVQKSSAFPPNL- 157
           P       GP  SP    L  P   P   G P     P  L A  P   +    FP    
Sbjct: 627 PAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERG 686

Query: 158 LTSPPSVA--------VAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIV 209
           +  PP  A            G+     AP AP           S+  P  +G P      
Sbjct: 687 VQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPG----------SQGAPGLQGMPG----- 731

Query: 210 STVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGP 269
                         + G A LP   P      A P+  D        SP   G   L GP
Sbjct: 732 --------------ERGAAGLPG--PKGDRGDAGPKGADG-------SPGKDGVRGLTGP 768

Query: 270 VSPPAALSL------STQSLPVVTSSQKTA-------GPNTPPDFPISLGSHLAPLHQSS 316
           + PP           S  S P   +  + A       GP  P  F    G+   P  +  
Sbjct: 769 IGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGE 828

Query: 317 FGSVQLLGQTGPSALSDP 334
            G     G  GP   + P
Sbjct: 829 PGDAGAKGDAGPPGPAGP 846


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score =  242 bits (617), Expect = 3e-63
 Identities = 507/2017 (25%), Positives = 713/2017 (35%), Gaps = 293/2017 (14%)

Query: 6    TETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPL------- 58
            T  +P T+         T+ LP++S  SV+     P P   P  +      PL       
Sbjct: 2254 TTPLPVTDASSVSTGHATS-LPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASS 2312

Query: 59   SAANQASPFP-----SPSTIASTPLEVPFPQSSS-GTALPLGTAPEAPTFLPNLIGPPIS 112
            ++   A+P P     S ST  +TPL V  P S+S G A PL     +     +    P++
Sbjct: 2313 ASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVT 2372

Query: 113  PAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSV 172
             ++ A +S    P L  T +SSA        P  V  +S+      T  P   ++ + + 
Sbjct: 2373 SSSSA-SSGHTTP-LPVTDASSASTG--DTTPLPVTDTSSASTGHATHLPVTGLSSASTG 2428

Query: 173  ITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQ 232
             T   P+      TN++   +        TP P    S+      TP+    +   S   
Sbjct: 2429 DTTRLPV------TNVSSASTG-----HATPLPVTSTSSASTGDTTPLPGTDTSSVSTGH 2477

Query: 233  TTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKT 292
            TTP      +S    DTT   V                SP +A +  T  LPV  +   +
Sbjct: 2478 TTPLLVTDASSVSTGDTTRLPV---------------TSPSSASTGHTTPLPVTDTPSAS 2522

Query: 293  AGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSS---TGAS 349
             G  TP   P++  S L+  H +S      L  T PS+ S     ++ V  +S   TG +
Sbjct: 2523 TGDTTP--LPVTNASSLSTRHATS------LHVTSPSSASTGHATSLPVTDTSAASTGHA 2574

Query: 350  YP--------SQRSVIPPLPSRNEVVPATVAAFPVVAP---SVDKGPSTISSITCSPSGS 398
             P        +      PLP  +    +T  A P+      S   G +T   +T + S S
Sbjct: 2575 TPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSAS 2634

Query: 399  LNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVS-SVG-TTPLVVTNPCTIAAAPTTT 456
               AT   ++ T+S+   S+ +AT   PL    P S S G TTPL VT+  +++    T+
Sbjct: 2635 TGHATPLPVTNTSSV---STGHAT---PLHVTSPSSASTGHTTPLPVTDASSVSTGHATS 2688

Query: 457  FEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLK 516
              V    S  + +G  +++  T P++       P   +   + +     S P+ D   + 
Sbjct: 2689 LPVTDASS--VFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVS 2746

Query: 517  N-----LP----SSVLVKFPTQKDLQTVPASLEG-------APFSPAQAGLTTKKDPTVL 560
                  LP    SSV     T   L ++ +   G          S A  G  T    T L
Sbjct: 2747 TGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSL 2806

Query: 561  PLVQAA-----PKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTS----- 610
              V        P    S  ST  +  +P++ + + A      PLP    +S+ T      
Sbjct: 2807 SSVSTGDTTPLPVTDTSSASTGHATSLPVT-DTSSASTGHATPLPDTDTSSASTGHATLL 2865

Query: 611  PLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYT 670
            P+   SSAS+    S    D++   + +   TP     P  SA      P     TS+ +
Sbjct: 2866 PVTDTSSASIGHATSLPVTDTSS--ISTGHATPLHVTSP-SSASTGHATPLPVTDTSSAS 2922

Query: 671  TT-ASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVA-PSPQNTCAPLATLVLAP 728
            T  A+P    + S A   H       T LP+  T+S +   A P P  + + ++T    P
Sbjct: 2923 TGHANPLHVTSPSSASTGHA------TPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTP 2976

Query: 729  EIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLT 788
             +P + PS +     TP         S   A A   +S     T D+       +    T
Sbjct: 2977 -LPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSAST 3035

Query: 789  YLADSPSPL----GVSVSPQTKRPPTKKGSA--GPDTPI-GNLSSPVSPVEASFLPENSL 841
              A +P P+     VS    T  P T   SA  G  TP+    +S  S  +A+ LP  SL
Sbjct: 3036 GQA-TPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSL 3094

Query: 842  SFQGSKDS-PATTHSPTPPSPKGAPTPSAVTPLSPKGV----TLPPKETP---TPSVVNL 893
            S   + D+ P    SP+  S  G  T   VT  S        +LP  +T    T    +L
Sbjct: 3095 SSVSTGDTTPLPVTSPSSAST-GHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSL 3153

Query: 894  PFP-----KEGPATP----------APKQAPALSMTSSSPKKARATPAPKGIPASPSPKG 938
            P         G  TP               P L   +SS     ATP     P+S S   
Sbjct: 3154 PVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGD 3213

Query: 939  APTPPAATPPSPKGGPATPSPKWAPTP---------PAATPPSPKGGPATPSP--KGAPT 987
                P     S   G ATP P    +          P     S   G ATP P    +  
Sbjct: 3214 TTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSV 3273

Query: 988  PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFP--------KGASTPPAAT 1039
                T P P   P++ S  G  TP  VT  S   +  ATP P         G +TP   T
Sbjct: 3274 STGDTMPLPVTSPSSAST-GHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVT 3332

Query: 1040 PPSPKGSPAATPLPKGAPTTPAA--TLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097
              S   +   TPLP  +P++ +   T P     P++ S     T P     S   G ATP
Sbjct: 3333 DTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATP 3392

Query: 1098 SP--KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPP-------KGA 1148
             P    + +      P P   L++         P     S   G ATP P          
Sbjct: 3393 LPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTG 3452

Query: 1149 PTTP--AATPPSPKGGLATPPP-------KGAPTT--PAATPPSPKGGLATPSP------ 1191
             TTP       S   G ATP P           TT  P     S   G ATP P      
Sbjct: 3453 DTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSS 3512

Query: 1192 -KGAPTTP--AATPPSPKGGLATPSPKGAPTTPAATPPS---PKGGLATPSPKGAPTTPA 1245
                 TTP       S   G ATP P    T+ A+T  +   P    ++ S   A   P 
Sbjct: 3513 VSTGDTTPLLVTDASSVSTGHATPLPV-TDTSSASTGDTTRLPVTDTSSASTGQATPLPV 3571

Query: 1246 ATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP 1305
              P S   G  TP P         +  S+  G  TP H  +P+ A     +P    +TS 
Sbjct: 3572 TIPSSSSSGHTTPLP-------VTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSS 3624

Query: 1306 PKGAPTPPAATPPSPKGSPG--TPPP--------KGAPTPPAVTPPSPKGT---PTLPAT 1352
                   P     +   S G  TP P         G  TP  VT  S   T     LP T
Sbjct: 3625 ASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVT 3684

Query: 1353 TPSSKG-GPTTP---SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI 1408
            + SS   G TTP   +     +   ATP     P   P S   G  +P P   P+S +  
Sbjct: 3685 SLSSVSTGDTTPLPVTDASSASTGHATPL----PVTIPSSVSTGDTMPLPVTSPSSAST- 3739

Query: 1409 PLSPKKAPATPVTREGAATPSKGDLTPPAVTPV-SLKKAPATSAPKGGPATPSSKGDPTL 1467
                    ATP+   G ++ S GD TP  VT   S     AT  P    ++ S+     L
Sbjct: 3740 ------GHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRL 3793

Query: 1468 PAVTPPSPKEPPA-PKQVATSSSPKKAPATPAPM---------GAPTLPAVIPSSPKEVP 1517
            P     S     A P  V ++SS      TP P+          A +LP    SS     
Sbjct: 3794 PVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGH 3853

Query: 1518 ATPSSRRDPIAPT---ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATP 1574
            ATP    D  + +   AT L   + ++++   A   P  +  S     A P P  + ++ 
Sbjct: 3854 ATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSA 3913

Query: 1575 SSKEASSPPAVTPSTYK-GAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAP 1633
            S+ + +  P    S+   G  +P  +  P   +S S  +  T P     S   G ATP P
Sbjct: 3914 STGDTTPLPVTNASSLSTGHATPLHVTSP---SSASRGDTSTLPVTDASSASTGHATPLP 3970

Query: 1634 --------KGTPTSPPVT-PSSLKDSPTSPASVT----CKMGATVP-------QASKGLP 1673
                     G  T  PVT  SS      +P  VT       G T P        AS G  
Sbjct: 3971 LTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHT 4030

Query: 1674 AKKGPTALKEVLVA-----PAPESTPIITAPTRKGPQTKKSS-----ATSPPICPDPSAK 1723
                 T    V        P   ++   T  T   P T  SS     AT  P+    SA 
Sbjct: 4031 TSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSAS 4090

Query: 1724 NGSKGP-----LSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAF 1778
             G   P     LS+V+     P+   SS T+    +S SP     P  +  S        
Sbjct: 4091 TGHATPLPVTSLSSVSTGHATPLAV-SSATSASTVSSDSPLKMETPGMTTPSLKTDGGRR 4149

Query: 1779 EKVLPKPESAS--VSAAPSPPVSLPLAPSPVPTLPPK 1813
                P P ++   +S  PS  +      +P+P LP +
Sbjct: 4150 TATSPPPTTSQTIISTIPSTAMHTRSTAAPIPILPER 4186



 Score =  231 bits (590), Expect = 4e-60
 Identities = 541/2189 (24%), Positives = 778/2189 (35%), Gaps = 334/2189 (15%)

Query: 2    PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCP-LSA 60
            P  A       + E  +   +T     +S+ S T + G   P+        P     +S 
Sbjct: 764  PDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGIST 823

Query: 61   ANQASPFPS-PSTIASTPLEVP--FPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALA 117
            + + + F S PS  + T          S+S  A+P+ T   A + +P    P +S A+ A
Sbjct: 824  SGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGM-ASSIVPGTFHPTLSEASTA 882

Query: 118  --------LASPMIAPTLKGTPSSSAPLA---------LVALAPHSVQKSSAFPPNLLTS 160
                      SP  +P      S  A             ++LA  +    S  PP    +
Sbjct: 883  GRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPP----T 938

Query: 161  PPSVAVAESGSVITLSAPIAPS-EPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTP 219
            PPS+      S  T +  ++PS   KT    + S   P P    S      T P H VT 
Sbjct: 939  PPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLH-VTD 997

Query: 220  MASIQSGVAS-LPQTTP-------TTTLAIASPQVKDT---------TISSVLISPQNP- 261
             +S+ +G A+ LP T+P       TT L +     + T         + SS       P 
Sbjct: 998  ASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPL 1057

Query: 262  ----GSLSLKGPVSPPAALSLSTQS------LPVVTSSQKTAGPNTPPDFPISLGSHLAP 311
                 S +  G V+P    SLS+ S      LPV  +S  + G  T    P++  S ++ 
Sbjct: 1058 PVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHAT--SLPVTDTSSVST 1115

Query: 312  LHQSSFGSVQLLGQTGPSALSDPTVKTISVD--HSS----TGASYPSQRSVIP-PLPSRN 364
             H +          +   A S P   T SV   H++    T AS  S     P P+ S +
Sbjct: 1116 GHTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLHVTDASSASTGQATPLPVTSLS 1175

Query: 365  EVVPATVAAFPVVAPS-VDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATY 423
             V        PV +PS    G +T   +T + S S   AT   ++  +S+   S+ +AT 
Sbjct: 1176 SVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSV---STDHAT- 1231

Query: 424  HYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTT------TFEVATCVSPPM--------SS 469
              P+      S+  TTPL VT+  + +    T      T  V+T  + P+        S+
Sbjct: 1232 SLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSAST 1291

Query: 470  GPISNIEPTSPAALVMAPVAPKE----PSTQVATTLRIPV-SPPLPDPEDLKNLPSSVLV 524
            G ++ +  TSP++       P       S     T+ +PV SP      D   LP +   
Sbjct: 1292 GHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDAS 1351

Query: 525  KFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAA-----PKNSPSFQSTSSS 579
               T     T P  +  A  S A  G  T    T L  V        P  SPS  ST  +
Sbjct: 1352 SVSTG---HTTPLHVTDA--SSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHA 1406

Query: 580  PEIPLSPEATLAKKSLGEPLPIGKPASSMTS-----PLGVNSSASVIKTDSYAGPD--SA 632
              + L  + + A      PLP+   +S  T      P+ + S+AS   T      D  SA
Sbjct: 1407 TPL-LVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSA 1465

Query: 633  GPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYT----TTASPFLEGTVSLAPKNH 688
                 +SL+    ++       P  V  T++  T   T    T+ S    G  +  P   
Sbjct: 1466 STGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTS 1525

Query: 689  PVKEGTLTTLPLV---PTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPS------- 738
                 T  T+PL    P+++      P P    + ++T    P +P + PS +       
Sbjct: 1526 LSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTP-LPVTSPSSASTGHTTP 1584

Query: 739  LPPAGTPPGTK-----------KVDGISHTSALAPV-----ASSPKECPTEDSGASATAS 782
            LP   T   +K                 HT+ L PV     AS+    P   + AS+ ++
Sbjct: 1585 LPVTDTSSASKGDTTPLPVTSPSSASTGHTTPL-PVTDTSSASTGDTTPLPVTNASSLST 1643

Query: 783  SKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD----TPIGNLSS---------PVS 829
               T  ++    SP   S    T  P T   SA        P+  LSS         PV+
Sbjct: 1644 GHATPLHVT---SPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVT 1700

Query: 830  PV------EASFLPENSLSFQGSKDS-PATTHSPTPPSPKGAPTPSAVTPLSP----KGV 878
             V      +A+ LP  SLS   + D+ P    SP+  S  G  +P  VT  S     +  
Sbjct: 1701 DVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSAST-GHASPLLVTDASSASTGQAT 1759

Query: 879  TLPPKETPTPSVVNL-PFPKEGPATPAPKQAPALSMTS-SSPKKARATPAPKGIPASPSP 936
             LP  +T + S  +  P P  G ++ +      L +T  SS    +A P P   P+S S 
Sbjct: 1760 PLPVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSAST 1819

Query: 937  KGAPTPPAATPPSPKGGPATPSPKWAPTPPAA--TPPSPKGGPATPSPKGAPTPPAATPP 994
                  P     S   G  T  P   P+  ++  T   P    ++ S   A +       
Sbjct: 1820 GDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDAS 1879

Query: 995  SPKGGPATPSP--------KGAPTPPAVTPPSPKGSPAATPFP--------KGASTPPAA 1038
            S   G  TP P         G  TP  VT  S   +  AT  P         G +TP   
Sbjct: 1880 SVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPV 1939

Query: 1039 TPPSPKGSPAATPLP----KGAPTTPAATLPSPKGGPATPSLKGAPTP-PAATPPSPKGG 1093
            T PS   S   TPLP       PT  A +LP       +    G  TP P     S   G
Sbjct: 1940 TSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVST---GHATPLPVTDASSVSTG 1996

Query: 1094 PATPSP----------KGAPMPPAATPPSPKGGLATPPHKGAPTTPAAT---PPSPKGGL 1140
             ATP P          +  P+P  +   +  G   T P     T+ A+T    P P   L
Sbjct: 1997 HATPLPVTDTSSVSTGQATPLPVTSLSSASTGD--TTPLPVTDTSSASTGQDTPLPVTSL 2054

Query: 1141 ATPPPKGAPTTPAATPPSPKGGLATP---PPKGAPTTPAATP--PSPKGGLATPSPKGAP 1195
            ++         P  +P S   G ATP       + +T  AT    +    ++T       
Sbjct: 2055 SSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHATALH 2114

Query: 1196 TTPAATPPSPKGGLATPSPKGAPTTPAA--TPPSPKGGLATPSPKGAPTTPAATPPSPKG 1253
             T A+   S   G  TP P  +P++ +   T P P    ++ S   A + P     S   
Sbjct: 2115 VTDAS---SLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSSAST 2171

Query: 1254 GPATPPP--------KGAPTP-PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS 1304
            G AT  P         G  TP P     S   G ATP    +P+ A      P     TS
Sbjct: 2172 GHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTS 2231

Query: 1305 PPK-GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGT---PTLPATTPSSKG-G 1359
                G  TP   T  S   +       G  TP  VT  S   T    +LP T+ SS   G
Sbjct: 2232 SASTGQATPLPVTSLSSAST-------GDTTPLPVTDASSVSTGHATSLPVTSLSSVSTG 2284

Query: 1360 PTTPSSKEGPTPPA---ATPSHKGGPAMTPPSPKRGPAIPSP--------KGDPTS-PAV 1407
             TTP     P+  +   ATP H         S   G A P P         GD T  P  
Sbjct: 2285 DTTPLPVTSPSSASTGHATPLH----VTDASSASTGHATPLPVTSLSSASTGDTTPLPVT 2340

Query: 1408 IPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPT- 1466
             P S     ATP+    A++ S GD TP  VT  S   +  T+      A+ +S GD T 
Sbjct: 2341 SPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTP 2400

Query: 1467 LPAVTPPSPKEPPAPKQVATS-SSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRD 1525
            LP     S     A     T  SS      T  P+   +  +   ++P  V +T S+   
Sbjct: 2401 LPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTG 2460

Query: 1526 PIAP-TATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA 1584
               P   T  S  +     P   L+  A +V +   T     P  +P++ S+   +  P 
Sbjct: 2461 DTTPLPGTDTSSVSTGHTTP--LLVTDASSVSTGDTT---RLPVTSPSSASTGHTTPLPV 2515

Query: 1585 V-TPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAP--------KG 1635
              TPS   G  +P   L     +S S + A +    +P S   G AT  P         G
Sbjct: 2516 TDTPSASTGDTTP---LPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTG 2572

Query: 1636 TPTSPPVT-PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTP 1694
              T  PVT  SS     T+P  VT    A+  QA+        P  + +   A   ++TP
Sbjct: 2573 HATPLPVTSTSSASTGDTTPLPVTDTYSASTGQAT--------PLPVTDTSSASTGDTTP 2624

Query: 1695 IITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPL-------LPVQKDSSK 1747
            +   P           AT  P+    S   G   PL   +P+         LPV  D+S 
Sbjct: 2625 L---PVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPLPV-TDASS 2680

Query: 1748 TAKG-------KDAS-----HSPKGPLAPPESKAS---TPLTAAAFEKV-------LPKP 1785
             + G        DAS     H+   P+  P S +S   TPL       V       LP  
Sbjct: 2681 VSTGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVT 2740

Query: 1786 ESASVS---AAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLP 1842
            +++SVS   A P P        +   T  P       S G     P    + A   +  P
Sbjct: 2741 DASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATP 2800

Query: 1843 LIPPEPISGGVPFQSVLVNMPTPKSAGIPV-PTPSAKQPVTKNNKGSGTESDSDESVPEL 1901
            L    P++        L ++ T  +  +PV  T SA      +   + T S S      L
Sbjct: 2801 L----PVTS-------LSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPL 2849

Query: 1902 EEQDSTQATTQQAQLAAAAEIDEEPVSKA 1930
             + D++ A+T  A L    +     +  A
Sbjct: 2850 PDTDTSSASTGHATLLPVTDTSSASIGHA 2878



 Score =  229 bits (585), Expect = 2e-59
 Identities = 517/2121 (24%), Positives = 743/2121 (35%), Gaps = 331/2121 (15%)

Query: 22   ETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVP 81
            +T  LP++S  S +     P     P  +      PL   + +S        AST   +P
Sbjct: 1485 DTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSS--------ASTGDTMP 1536

Query: 82   FPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVA 141
             P +S  +A    T P   T   ++     +P  L + SP  A T       + PL +  
Sbjct: 1537 LPVTSPSSASTGDTTPLPVTDASSVSTGHTTP--LPVTSPSSAST-----GHTTPLPVTD 1589

Query: 142  LAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKG 201
             +  S   ++  P   +TSP S +   +  +       A +   T L    +  +     
Sbjct: 1590 TSSASKGDTTPLP---VTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHA 1646

Query: 202  TPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVL-ISPQN 260
            TP      S+      TP+    +  AS    TP     ++S    DTT   V  +S  +
Sbjct: 1647 TPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSAS 1706

Query: 261  PGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTP---PDFPISLGSHLAPLHQSSF 317
             G  +     S  +  +  T  LPV + S  + G  +P    D   +      PL  +  
Sbjct: 1707 TGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDT 1766

Query: 318  GSVQL-----LGQTG-PSALSDPTVK--TISVDHSSTGASYPSQRSVIPPLPSRNEVVPA 369
             SV       L  TG  SA +D T +     V  +STG + P       P+ S +     
Sbjct: 1767 SSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPL------PVTSPSSASTG 1820

Query: 370  TVAAFPVV-APSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLV 428
                 PV  A S   G +T   +T   S S    TS  ++  +S+   S+ +AT      
Sbjct: 1821 DTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSV---STGHATSLLVTD 1877

Query: 429  AQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPM---SSGPISNIEPTSPAALVM 485
            A   VS+  TTPL VT+  + +   TT   V    S      +S P++++   S      
Sbjct: 1878 ASS-VSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTP 1936

Query: 486  APVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFS 545
             PV     ++   TT       PLP   D  ++P+      P   D  +V       P  
Sbjct: 1937 LPVTSPSSASSGHTT-------PLP-VTDASSVPTGHATSLPVT-DASSVSTG-HATPLP 1986

Query: 546  PAQAGLTTKKDPTVLPLV--------QAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGE 597
               A   +    T LP+         QA P    S  S S+    PL P    +  S G+
Sbjct: 1987 VTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPL-PVTDTSSASTGQ 2045

Query: 598  PLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVA-AFPLESADPA 656
              P+  P +S++S    +++   + + S A    A PLL +   + +   A  L   D +
Sbjct: 2046 DTPL--PVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVTDAS 2103

Query: 657  GVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHP--VKEGTLTTLPLVPTASENCPVAPSP 714
             V+  T   T+ + T AS    G  +  P   P     G  T LP+  T+S +   A S 
Sbjct: 2104 SVS--TGHATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSL 2161

Query: 715  QNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTED 774
              T    A+   A  +P +  S +     TP        ++ TS+    AS+ +  P   
Sbjct: 2162 PVTDTSSASTGHATSLPVTDTSSASTGHATPLP------VTDTSS----ASTGQATPLPV 2211

Query: 775  SGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSA--GPDTPIGNL-SSPVSPV 831
            +  S+ ++       + D+ S    S    T  P T   SA  G  TP+    +S VS  
Sbjct: 2212 TSPSSASTGHAIPLLVTDTSS---ASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTG 2268

Query: 832  EASFLPENSLSFQGSKDS-PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSV 890
             A+ LP  SLS   + D+ P    SP+  S  G  TP  VT  S          TP P V
Sbjct: 2269 HATSLPVTSLSSVSTGDTTPLPVTSPSSAST-GHATPLHVTDASSASTG---HATPLP-V 2323

Query: 891  VNLPFPKEGPATPAPKQAPALSMT----------SSSPKKARATPAPKGIPASPSPKGAP 940
             +L     G  TP P  +P+ + T          +SS      TP P    +S S  G  
Sbjct: 2324 TSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSAS-SGHT 2382

Query: 941  TP-PAATPPSPKGGPATPSPKWAPTPPAATPPS---PKGGPATPSPKGAPTPPAATPPSP 996
            TP P     S   G  TP P    T  A+T  +   P  G ++ S       P     S 
Sbjct: 2383 TPLPVTDASSASTGDTTPLPV-TDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSA 2441

Query: 997  KGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGA 1056
              G ATP P  + +  +    +P      +    G +TP   T  S   +   T LP  +
Sbjct: 2442 STGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTS 2501

Query: 1057 PTT---------PAATLPSPKGGPATP---------SLKGAPTPPAATPPSPKGGPATPS 1098
            P++         P    PS   G  TP         S + A +    +P S   G AT  
Sbjct: 2502 PSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSL 2561

Query: 1099 P----------KGAPMPPAATPPSPKGGLATPPHKG--APTTPAATP------PSPKGGL 1140
            P             P+P  +T  +  G     P     + +T  ATP       S   G 
Sbjct: 2562 PVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGD 2621

Query: 1141 ATPPP---KGAPTTPAATP------PSPKGGLATPPPKGAPTTPAA--TPPSPKGGLATP 1189
             TP P     + +T  ATP       S   G ATP    +P++ +   T P P    ++ 
Sbjct: 2622 TTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSV 2681

Query: 1190 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA--TPPSPKGGLATPSPKGAPTTPAAT 1247
            S   A + P     S   G AT  P   P++ ++  T P P    ++ S   A + P   
Sbjct: 2682 STGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTD 2741

Query: 1248 PPSPKGGPATPPP--------KGAPTP-PAATPPSLKGGLATP--------PHKGAPNPA 1290
              S   G ATP P         G  TP P  +  S+  G  TP           G   P 
Sbjct: 2742 ASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPL 2801

Query: 1291 VVTPPSPKGGPATSPPKGAPTPPAAT------PPSPKGSPGTPPPKGAPTPPAVTPPSPK 1344
             VT  S      T+P     T  A+T      P +   S  T      P P   T  +  
Sbjct: 2802 PVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTG--HATPLPDTDTSSAST 2859

Query: 1345 GTPTLPATTPSSKGG-------PTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPS 1397
            G  TL   T +S          P T +S    +   ATP H      +P S   G A P 
Sbjct: 2860 GHATLLPVTDTSSASIGHATSLPVTDTSSI--STGHATPLH----VTSPSSASTGHATPL 2913

Query: 1398 PKGDPTSPAV---------IPLSPKKAPATPV-------TREGAATP---------SKGD 1432
            P  D +S +           P S     ATP+          G ATP         S GD
Sbjct: 2914 PVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGD 2973

Query: 1433 LTP-PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE-PPAPKQVATSSSP 1490
             TP P  +P S      T  P    ++ S+     LP  +  S       P  V  +SS 
Sbjct: 2974 TTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSA 3033

Query: 1491 KKAPATPAPMGAPTLPAVIPSSPKEVPAT-PSS----RRDPIAPTATLLSKKTPATLAPK 1545
                ATP P+   +L +V       +P T PSS       P+  T    +    AT  P 
Sbjct: 3034 STGQATPLPV--TSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPV 3091

Query: 1546 EAL--IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASS--------PPAVTPSTYKGAPS 1595
             +L  +    T P P  +P+  +   A + P +  +S+        P   T S Y G  +
Sbjct: 3092 TSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTT 3151

Query: 1596 PKELLIPPAVTSPSPKEAPTPPAVTPPSP-EKGPATP--------APKGTPTSPPVT-PS 1645
                 +P   TS S     TP  VT  S    G ATP        A  G  T   VT PS
Sbjct: 3152 S----LPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPS 3207

Query: 1646 SLKDSPTSPASVT----CKMGATVPQASKGL-PAKKGPTA---LKEVLVAPAPESTPI-- 1695
            S     T+P  VT       G   P    GL  A  G T    + ++  A   ++TP+  
Sbjct: 3208 SASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPV 3267

Query: 1696 ---------------ITAPTRKG-------PQTKKSS-----ATSPPICPDPSAKNGSKG 1728
                           +T+P+          P T  SS     AT  P+    SA  G   
Sbjct: 3268 TNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTT 3327

Query: 1729 PL-------STVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKV 1781
            PL       ++      LPV   SS +       H      A     ++ P+T A+    
Sbjct: 3328 PLPVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSAST 3387

Query: 1782 -----LPKPESASVS---AAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLA 1833
                 LP  +++SVS   A P P  SL    +   T  P      +S G     P   L+
Sbjct: 3388 GHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLS 3447

Query: 1834 PADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESD 1893
                 +  PL               LV   +  S G   P P            + T S 
Sbjct: 3448 SVSTGDTTPL---------------LVTDASSVSTGHATPLPV-----------TDTSSA 3481

Query: 1894 SDESVPELEEQDSTQATTQQA 1914
            S      L   D++ A+T QA
Sbjct: 3482 STGDTTRLPVTDTSSASTGQA 3502



 Score =  221 bits (562), Expect = 8e-57
 Identities = 459/1904 (24%), Positives = 686/1904 (36%), Gaps = 237/1904 (12%)

Query: 50   SPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGP 109
            S +PQ+ P  +    +  P  +  + T   V  P + + T    G++  A    P+ I P
Sbjct: 625  STSPQESPAVSQRGHTQAPQTTQESQTTRSVS-PMTDTKTVTTPGSSFTASGHSPSEIVP 683

Query: 110  PISPAALALASPMIAPTLKGTPSSSAPLALVA--------LAPH---SVQKSSAFPPNLL 158
              +P   A  +   APT  G  + +   AL A        L P    S+ K+ A    L 
Sbjct: 684  QDAPTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGAL--TLA 741

Query: 159  TSPPSVAVAESGSVITLSAPIAP--SEPKTNLNKVPSEVVPNPKGTPSPPCIVS-TVPYH 215
             S  S      G   + SA  +P  +   T+ ++  S        T  P    S T    
Sbjct: 742  NSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAG 801

Query: 216  CVTPMASIQSGVASLPQ----TTPTTTLAIASPQVKDTTISS---VLISPQNPGSLSLKG 268
              TP +S  SG          T+  TT   ++P     T  S   +L +  + G++    
Sbjct: 802  TATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAI---- 857

Query: 269  PVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGP 328
            PVS   A S+   +     S   TAG  T    P S  +  +P   ++   +    +T  
Sbjct: 858  PVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSA--SPQETAAISRMAQTQRTRT 915

Query: 329  SALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTI 388
            S  SD    TIS+   +T        S +PP P             P +  +    P T 
Sbjct: 916  SRGSD----TISLASQATDTF-----STVPPTP-------------PSITSTGLTSPQT- 952

Query: 389  SSITCSPSGSLNVATSFSLSPTTSL-ILKSSPNATYHYPLVAQMPVSSVGT---TPLVVT 444
             + T SPSGS    T+  +S  T L +  +S  +T H   +     SSV T   TPL VT
Sbjct: 953  ETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVT 1012

Query: 445  NPCTIAAAPTTTFEVATCVSPP---MSSGPISNIEPTSPAALVMAPVAPKE--------- 492
            +P +++   TT   V    S     ++  P+++    S       PV             
Sbjct: 1013 SPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTP 1072

Query: 493  -PSTQVATTLRIPVSP-PLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAG 550
             P T +++      +P P+ D        ++ L    T          L     S A  G
Sbjct: 1073 LPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTG 1132

Query: 551  LTTK---KDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGE--PLPIGKPA 605
              T     D + +      P +     S S+    PL P  +L+  S G+  PLP+  P+
Sbjct: 1133 HATSLPVTDTSSVSTGHTTPLHVTDASSASTGQATPL-PVTSLSSVSTGDTTPLPVTSPS 1191

Query: 606  SSMTSPLGVNSSASVIKTDSYAGPDSAGPLL---KSSLITPTVAAFPLESADPAGVAPTT 662
            S+ T     +++  ++   S A    A PL     SS+ T    + P+     A    TT
Sbjct: 1192 SASTG----HATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTT 1247

Query: 663  AKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCP-VAP----SPQNT 717
                 T T++AS   + T  L      V  G  T LP+  T+S +   V P    SP + 
Sbjct: 1248 PLPV-TDTSSASTG-QATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSA 1305

Query: 718  CAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGA 777
                AT +    +  +    ++P   T P +               AS+    P   + A
Sbjct: 1306 STGHATPLPVTSLSSASTGDTMPLPVTSPSS---------------ASTGDTTPLPVTDA 1350

Query: 778  SATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLP 837
            S+ ++   T  ++ D+ S                 G A P  P+ +LSS VS  + + LP
Sbjct: 1351 SSVSTGHTTPLHVTDASS--------------ASTGQATP-LPVTSLSS-VSTGDTTPLP 1394

Query: 838  ENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTP---LSPKGVTLPPKETPTPSVVN-- 892
              S S   +  +     + T  +  G  TP  VT    +S    T  P   P+ +     
Sbjct: 1395 VTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHT 1454

Query: 893  LPFPKEGPATPAPKQAPALSMT-SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK 951
             P P    ++ +  QA +L +T +SS      TP P    +S S  G  TP   T PS  
Sbjct: 1455 TPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSAST-GHVTPLHVTSPSSA 1513

Query: 952  G-GPATPSPKWAPTPPAA--TPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGA 1008
              G ATP P  + +  +   T P P   P++ S       P     S   G  TP P  +
Sbjct: 1514 STGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTS 1573

Query: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP--KGAPTTPAATLPS 1066
            P+  +    +P      +   KG +TP   T PS   +   TPLP    +  +   T P 
Sbjct: 1574 PSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPL 1633

Query: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAA--TPPSPKGGLATPPHKG 1124
            P    ++ S   A      +P S   G ATP P  +    +     P P  GL++     
Sbjct: 1634 PVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDD 1693

Query: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP-- 1182
                P     S   G ATP        P  +  S   G  TP P  +P++ +    SP  
Sbjct: 1694 TTRLPVTDVSSASTGQATP-------LPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLL 1746

Query: 1183 -------KGGLATPSP--KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1233
                     G ATP P    +  + A   P P  GL++ S       P     S   G A
Sbjct: 1747 VTDASSASTGQATPLPVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQA 1806

Query: 1234 TPSPKGAPTTPAA--TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP-PHKGAPNPA 1290
             P P  +P++ +   T P P    ++       + P   P S   G  T  P   A + +
Sbjct: 1807 IPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVS 1866

Query: 1291 VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGT---P 1347
                 S     A+S   G  TP    P +   S  T    G  TP  VT  S   T    
Sbjct: 1867 TGHATSLLVTDASSVSTGDTTP---LPVTDTNSAST----GDTTPLHVTDASSVSTGHAT 1919

Query: 1348 TLPATTPSSKG-GPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTS-P 1405
            +LP T+ SS   G TTP        P  +PS       TP       ++P+  G  TS P
Sbjct: 1920 SLPVTSLSSASTGDTTPL-------PVTSPSSASSGHTTPLPVTDASSVPT--GHATSLP 1970

Query: 1406 AVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATP------ 1459
                 S     ATP+    A++ S G  TP  VT         TS+   G ATP      
Sbjct: 1971 VTDASSVSTGHATPLPVTDASSVSTGHATPLPVTD--------TSSVSTGQATPLPVTSL 2022

Query: 1460 --SSKGDPTLPAVTPPSPKE--PPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKE 1515
              +S GD T   VT  S        P  V + SS      TP P+ +P+  +   ++P  
Sbjct: 2023 SSASTGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLL 2082

Query: 1516 VPATPSSRRDPIAPTATLLSKKTPATLAPKEAL-IPPAMTVPSPKKTPAIPTPKEAPATP 1574
            V  T +S       T+ L++  +  +     AL +  A ++ +   T   P P  +P++ 
Sbjct: 2083 V--TDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTT---PLPVTSPSSA 2137

Query: 1575 SSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAP- 1633
            S+ + +  P    S+     +    L     +S S   A + P     S   G ATP P 
Sbjct: 2138 STGDTTPLPVTDTSSVSTGHATS--LPVTDTSSASTGHATSLPVTDTSSASTGHATPLPV 2195

Query: 1634 -------KGTPTSPPVT-PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVL 1685
                    G  T  PVT PSS       P  VT    A+  QA+        P  +  + 
Sbjct: 2196 TDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQAT--------PLPVTSLS 2247

Query: 1686 VAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP-----LLP 1740
             A   ++TP+   P           ATS P+    S   G   PL   +P+        P
Sbjct: 2248 SASTGDTTPL---PVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATP 2304

Query: 1741 VQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSL 1800
            +    + +A    A+  P   L+   +  +TPL   +       P SAS   A    V+ 
Sbjct: 2305 LHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTS-------PSSASTGHATPLHVTD 2357

Query: 1801 PLAPSPVPTLP-PKQQFLPSSPGLVLESPSKPLAPADEDELLPL 1843
              + S   T P P      +S G     P    + A   +  PL
Sbjct: 2358 ASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPL 2401



 Score =  162 bits (409), Expect = 4e-39
 Identities = 350/1460 (23%), Positives = 490/1460 (33%), Gaps = 214/1460 (14%)

Query: 565  AAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTD 624
            + P  SPS  + + +     SP    A  SL          +SM +   +  + S   T 
Sbjct: 220  STPSFSPSVHNVTGTVSQKTSPSGETATSSL-----CSVTNTSMMTSEKITVTTSTGSTL 274

Query: 625  SYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLA 684
               G  S+ P+   SL+  T AA  L + DP G +P T   TST  TTA           
Sbjct: 275  GNPGETSSVPVT-GSLMPVTSAA--LVTFDPEGQSPATFSRTSTQDTTA----------F 321

Query: 685  PKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGT 744
             KNH  +    T +  + T            NT  P+ T  +        PS ++     
Sbjct: 322  SKNHQTQSVETTRVSQINTL-----------NTLTPVTTSTVLSSPSGFNPSGTVSQETF 370

Query: 745  PPGTKKVDGISHTSALAPVASSPKECPTEDSGA-----SATASSKGTLTYLADSPSPLGV 799
            P G       S  S    V S     PT            + S  GT++ +    S +  
Sbjct: 371  PSGETTTSSPSSVSNTFLVTSKVFRMPTSRDSTLGNTEETSLSVSGTISAITSKVSTIWW 430

Query: 800  SVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQ-GSKDSPATTHS--- 855
            S +  T   P+   S  P       +      E +  P    SF  G      T H    
Sbjct: 431  SDTLSTALSPS---SLPPKISTAFHTQQSEGAETTGRPHERSSFSPGVSQEIFTLHETTT 487

Query: 856  -PTPPSPKGAPT------PSAVTPLSPKGVTLPPKETPTPSVVNLP-----FPKEGPATP 903
             P+  S KG  T      PS  T  + + VT  P      ++  +P       + G  T 
Sbjct: 488  WPSSFSSKGHTTWSQTELPSTSTGAATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTT 547

Query: 904  APKQAPALSMTSSSPKKARAT--PAPKGIPASPSPKGAPTPPAATPPSPKGGP------- 954
                +  L  T+ +  + + T      G     SP  + T    T  SP   P       
Sbjct: 548  YSSHSTTLPKTTGAGAQTQWTQETGTTGEALLSSPSYSVTQMIKTATSPSSSPMLDRHTS 607

Query: 955  --ATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP 1012
               T +P    +   +T  SP+  PA  S +G    P  T  S      +P      T  
Sbjct: 608  QQITTAPSTNHSTIHSTSTSPQESPAV-SQRGHTQAPQTTQESQTTRSVSPM---TDTKT 663

Query: 1013 AVTPPSPKGSPAATP---FPKGASTPPAAT--PPSPKGSPAATPLP----KGAPTTPAAT 1063
              TP S   +   +P    P+ A T  AAT   P+P G    T  P    + AP++  AT
Sbjct: 664  VTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDAT 723

Query: 1064 LPSPKGGPATPSLKGAPT---PPAATPPSPKGGPATPSPKGAPMPPAA---------TPP 1111
            L  P GG +  S  GA T      +TP  P+G   + S   +P   AA         T  
Sbjct: 724  L-GPSGGTSL-SKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQAESTEA 781

Query: 1112 SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGA----------------------- 1148
            S +   + P   G+ TT A T      G +   P G+                       
Sbjct: 782  SGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTT 841

Query: 1149 -PTTPAATPPSPKGGLATPPPKGAPTTPAATPP--SPKGGLATPSPKGAPTTPAATPPSP 1205
              TT   +  +  G +       +   P    P  S       P+ + +PT+P+A+P   
Sbjct: 842  QSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQET 901

Query: 1206 KG------GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP--------PSP 1251
                       T + +G+ T   A+  +       P+P    +T   +P        PS 
Sbjct: 902  AAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSG 961

Query: 1252 KGGPATPPPKGAPTP-PAATPPSLKGGLATPPH--------KGAPNPAVVTPPSPKGGPA 1302
             G   T       TP P     S   G  TP H         G   P  VT PS      
Sbjct: 962  SGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGH 1021

Query: 1303 TSPPKGAPTPPAAT---PPSPKGSPGTPPPKGAPTPPAVTPPSPKGT---PTLPATTPSS 1356
            T+P     T   +T    P P  S  +    G  TP  VT  S   T     LP T+ SS
Sbjct: 1022 TTPLPVTDTSSESTGHVTPLPVTS-FSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSS 1080

Query: 1357 KG-GPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415
               G TTP      T  A+T      P     S   G   P P  D +S      S   A
Sbjct: 1081 ASTGDTTPLPVT-DTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSS-----ASTGHA 1134

Query: 1416 PATPVTREGAATPSKGDLTPPAVTPV-SLKKAPATSAPKGGPATPSSKGDPTLPAVTPPS 1474
             + PVT    ++ S G  TP  VT   S     AT  P    ++ S+     LP  +P S
Sbjct: 1135 TSLPVT--DTSSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSS 1192

Query: 1475 PKEPPA-PKQVATSSSPKKAPATPAPM---------GAPTLPAVIPSSPKEVPATPSSRR 1524
                 A P  V  +SS     ATP P+          A +LP  IPS+      TP    
Sbjct: 1193 ASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPL--- 1249

Query: 1525 DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSP-KKTPAIPTPKEAPATPSSKEASSPP 1583
             P+  T++  + +  + L    + +    T P P   T +  T    P   +S  ++S  
Sbjct: 1250 -PVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTG 1308

Query: 1584 AVTPSTYKGAPSPKE-LLIPPAVTSPSPKEA--PTP-PAVTPPSPEKGPATP-------- 1631
              TP       S      +P  VTSPS       TP P     S   G  TP        
Sbjct: 1309 HATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASS 1368

Query: 1632 APKGTPTSPPVTP-SSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAP 1690
            A  G  T  PVT  SS+    T+P  VT    A+   A+        P  + +   A   
Sbjct: 1369 ASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHAT--------PLLVTDTSSASTG 1420

Query: 1691 ESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAK 1750
             +TP+   P           ATS P+    +A  G   PL     +     Q  S     
Sbjct: 1421 HATPL---PVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTD 1477

Query: 1751 GKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTL 1810
                S     PL  P +  S+  T       +  P SAS   A   PV+   + S   T+
Sbjct: 1478 TSSVSTGDTTPL--PVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTM 1535

Query: 1811 PPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGI 1870
            P           L + SPS   A   +   LP+     +S G    +  + + +P SA  
Sbjct: 1536 P-----------LPVTSPSS--ASTGDTTPLPVTDASSVSTG---HTTPLPVTSPSSAST 1579

Query: 1871 PVPTPSAKQPVTKNNKGSGT 1890
               TP      +  +KG  T
Sbjct: 1580 GHTTPLPVTDTSSASKGDTT 1599



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 261/1254 (20%), Positives = 397/1254 (31%), Gaps = 199/1254 (15%)

Query: 746  PGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQT 805
            PGT +   I+ +   APV S+           S TA+ +G  T  +   S   +S S Q 
Sbjct: 27   PGTTEDTLITGSKTAAPVTST----------GSTTATLEGQSTAASSRTSNQDISASSQN 76

Query: 806  KRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP 865
             +  +              +   S  +   L +   S   S  S        PP      
Sbjct: 77   HQTKS--------------TETTSKAQTDTLTQMMTSTLFSSPSVHNVMETAPPDEMTTS 122

Query: 866  TPSAVTP---LSPKGVTLPPK------------------ETPTPSVVNLPFPKEGPATPA 904
             PS+VT    ++ K +T+                      TP  S V++   +EG +   
Sbjct: 123  FPSSVTNTLMMTSKTITMTTSTDSTLGNTEETSTAGTESSTPVTSAVSITAGQEGQSRTT 182

Query: 905  PKQAPALSMTSSSPKK-ARATPAPKGIPASPSPKGAPTPPAATPP------------SPK 951
              +      ++SS     R+T   +    S       + P+ +P             SP 
Sbjct: 183  SWRTSIQDTSASSQNHWTRSTQTTRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPS 242

Query: 952  GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTP 1011
            G  AT S          T        +T S  G P   ++ P +    P T +      P
Sbjct: 243  GETATSSLCSVTNTSMMTSEKITVTTSTGSTLGNPGETSSVPVTGSLMPVTSAALVTFDP 302

Query: 1012 PAVTPP--SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG 1069
               +P   S   +   T F K   T    T    + +   T      P T +  L SP G
Sbjct: 303  EGQSPATFSRTSTQDTTAFSKNHQTQSVETTRVSQINTLNTL----TPVTTSTVLSSPSG 358

Query: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP 1129
                      P+   +    P G   T SP                 L T      PT+ 
Sbjct: 359  FN--------PSGTVSQETFPSGETTTSSPSSVS----------NTFLVTSKVFRMPTSR 400

Query: 1130 AAT-PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1188
             +T   + +  L+      A T+  +T       +          +P++ PP       T
Sbjct: 401  DSTLGNTEETSLSVSGTISAITSKVST-------IWWSDTLSTALSPSSLPPKISTAFHT 453

Query: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248
               +GA TT     P  +   + P       T   T   P    ++ S KG  T      
Sbjct: 454  QQSEGAETTGR---PHERSSFS-PGVSQEIFTLHETTTWP----SSFSSKGHTTWSQTEL 505

Query: 1249 PSPKGGPATPPPKGAP-TPPAATPPSLKGGLATPPHKGAPNP----AVVTPPSPKGGPAT 1303
            PS   G AT    G P T  A T P +   ++     G P      +   P +   G  T
Sbjct: 506  PSTSTGAATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQT 565

Query: 1304 SPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTP 1363
               +   T   A   SP  S          T    T  SP  +P L   T       TT 
Sbjct: 566  QWTQETGTTGEALLSSPSYSV---------TQMIKTATSPSSSPMLDRHTSQQI---TTA 613

Query: 1364 SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTRE 1423
             S    T  + + S +  PA++     + P   + +   T+ +V P++  K   TP +  
Sbjct: 614  PSTNHSTIHSTSTSPQESPAVSQRGHTQAPQ--TTQESQTTRSVSPMTDTKTVTTPGSSF 671

Query: 1424 GAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ 1483
             A+  S  ++ P        + AP  SA       P+  G  T    T            
Sbjct: 672  TASGHSPSEIVP--------QDAPTISAATTFAPAPTGDGHTTQAPTT------------ 711

Query: 1484 VATSSSPKKAPATPAPMGAPTLPAV-IPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL 1542
             A  ++P    AT  P G  +L      +    V +TP          +   S  T A +
Sbjct: 712  -ALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAM 770

Query: 1543 A---PKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKG------- 1592
                  E+      T  S   +    T     ATPSS  AS     TPS  +G       
Sbjct: 771  THTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGAS---GTTPSGSEGISTSGET 827

Query: 1593 -------------APSPKELLIPPAVTSPSPKEAPTPPAVTPPS--PEKGPATPAPKGTP 1637
                           S  ELL   A     P       ++ P +  P    A+ A + T 
Sbjct: 828  TRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTG 887

Query: 1638 TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697
             S P +PS+   SP   A+++        + S+G       +   +   +  P + P IT
Sbjct: 888  QSSPTSPSA---SPQETAAISRMAQTQRTRTSRGSDTISLASQATDTF-STVPPTPPSIT 943

Query: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSS--------KTA 1749
            +     PQT+  +     + P  S K  +   +S   P P+      S+          A
Sbjct: 944  STGLTSPQTETHT-----LSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDA 998

Query: 1750 KGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVS---AAPSPPVSLPLAPSP 1806
                  H+   P+  P S ++   T       LP  +++S S     P P  S   A + 
Sbjct: 999  SSVSTGHATPLPVTSPSSVSTGHTTP------LPVTDTSSESTGHVTPLPVTSFSSASTG 1052

Query: 1807 VPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVL-VNMPTP 1865
              T  P      +S G V   P   L+ A   +  PL   +  S      + L V   + 
Sbjct: 1053 DSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSS 1112

Query: 1866 KSAGIPVPTP-----SAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQA 1914
             S G   P P     SA      +   + T S S      L   D++ A+T QA
Sbjct: 1113 VSTGHTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLHVTDASSASTGQA 1166



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 96/408 (23%), Positives = 151/408 (37%), Gaps = 55/408 (13%)

Query: 2    PGEATETVPATEQE---LPQPQAETAVLPMSSALSVTA-ALGQPGPTLPPPCSPAPQQCP 57
            P   T+T  A+  +   LP     +A    ++ L VT+ +    G T P P +       
Sbjct: 3776 PLPVTDTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVST 3835

Query: 58   LSAAN-QASPFPSPSTIASTPLEVPFPQS-SSGTALPLGTAPEAPTFLPNLIGPPI-SPA 114
              A +   +   S ST  +TPL V    S S+G A PL     +     +    P+ SP+
Sbjct: 3836 GHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPS 3895

Query: 115  ALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVIT 174
            + +       P    + +S+     + +   S   +    P  +TSP S   A  G   T
Sbjct: 3896 SASTGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSS---ASRGDTST 3952

Query: 175  LSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTT 234
            L    A S    +              TP P   +S+V     TP+    +  AS  Q T
Sbjct: 3953 LPVTDASSASTGH-------------ATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQAT 3999

Query: 235  PTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSL---------------- 278
            P    +++S    DTT   V I        +   PV+  +++S                 
Sbjct: 4000 PLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSAST 4059

Query: 279  -STQSLPVVTSSQKTAGPNTP---PDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDP 334
              T  LPV  +S  + G  TP    D   +   H  PL  +S  SV   G   P A+S  
Sbjct: 4060 GDTTPLPVTDTSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVS-TGHATPLAVSSA 4118

Query: 335  T-VKTISVDH----SSTGASYPS------QRSVIPPLPSRNEVVPATV 371
            T   T+S D      + G + PS      +R+   P P+ ++ + +T+
Sbjct: 4119 TSASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTI 4166


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  239 bits (609), Expect = 3e-62
 Identities = 312/1173 (26%), Positives = 381/1173 (32%), Gaps = 207/1173 (17%)

Query: 699  PLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTS 758
            P  PT   N      P+    P       P IP     P +P     PG+    GI  + 
Sbjct: 92   PTAPTRPPNGQGPQGPKGDPGP-------PGIPGRNGDPGIPGQPGSPGSPGPPGICESC 144

Query: 759  ALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD 818
               P   SP+    +     A          LA  P P G         PP   G  GP 
Sbjct: 145  PTGPQNYSPQYDSYDVKSGVAVGG-------LAGYPGPAG---------PP---GPPGPP 185

Query: 819  TPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPK-G 877
               G+  SP SP            +QG    P       PP P GA  PS       + G
Sbjct: 186  GTSGHPGSPGSP-----------GYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESG 234

Query: 878  VTLPPKETPTPSVVNLPFPKEGPATPAPKQ---------------APALSMTSSSPKKAR 922
                P E   P    +  P   P  P  K                AP L   +  P +  
Sbjct: 235  RPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENG 294

Query: 923  ATPAPKGIPASPSPKGAPTPPAAT-------------------PPSPKGGPATPSPKWAP 963
            A P P G   +P  +G P  P A                    PP   G P +P  K   
Sbjct: 295  A-PGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAK-GE 352

Query: 964  TPPAATP-----PSPKGGPATPSPKGAPTPPAATPPSPKGGPATPS---PKGAPTPPAVT 1015
              PA +P     P  +G P      GA  PP   PP   G P       P G P  P + 
Sbjct: 353  VGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPG--PPGINGSPGGKGEMGPAGIPGAPGLM 410

Query: 1016 ----PPSPKGSPAATPFPKGASTPP---AATPPSPKGSPAATPLPKGAPTTPAATLPSPK 1068
                PP P G+  A     GA  P    A   P P+G         G P  P A     K
Sbjct: 411  GARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEA----GIPGVPGAKGEDGK 466

Query: 1069 -GGPATPSLKGAP-------TPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120
             G P  P   G P        P    P  P G P    P G    P   P  P+G    P
Sbjct: 467  DGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPG--PAGPRGAAGEP 524

Query: 1121 PHKGAPTTPA--ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1178
               G P  P     P SP G    P   G P      PP  +G    P P G P+ P   
Sbjct: 525  GRDGVPGGPGMRGMPGSPGG----PGSDGKPG-----PPGSQGESGRPGPPG-PSGPRGQ 574

Query: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT----PPSP------ 1228
            P    G +  P PKG    P       +GG   P P+G P     T    PP P      
Sbjct: 575  P----GVMGFPGPKGNDGAPGKN--GERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGD 628

Query: 1229 KGGLATPSPKGAPTTPAAT-PPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAP 1287
            KG    P P+G    P    PP   G P  P PKG    P A  P  KG    P  +G P
Sbjct: 629  KGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGA--PGGKGDAGAPGERGPP 686

Query: 1288 NPAVVT-------PPSPKGGPATSPPKGAP----TPPAATPPSPKGSPGTPPPKGAPTPP 1336
              A          PP P+GG   + P G P    TP     P  +G  G+P PKG    P
Sbjct: 687  GLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEP 746

Query: 1337 AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG---GPAMTPPSPKRGP 1393
                P   G P         K GP  P+   GP  PA  P  KG    P +   +  RG 
Sbjct: 747  G--GPGADGVP--------GKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGS 796

Query: 1394 AIPSPKGD--PTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPA--- 1448
              P  +G+  P  PA  P +P +        E  A   KG+  PP V        PA   
Sbjct: 797  --PGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPP 854

Query: 1449 ----TSAPKGGPATPSSKGDPTLPAVT-PPSPKEPPAPKQVATSSSPKKAPATPAPMGAP 1503
                    +G P  P + G P    +  PP     P P   + S      P      GAP
Sbjct: 855  GPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAP 914

Query: 1504 TLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKE-ALIPPAMTVPSPKKTP 1562
              P V  S PK     P  +  P A       +  P    P   A I  A  +  P   P
Sbjct: 915  GSPGV--SGPKGDAGQPGEKGSPGA-------QGPPGAPGPLGIAGITGARGLAGP---P 962

Query: 1563 AIPTPKEAPATPSSK-EASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621
             +P P+ +P     K E+  P A   S  +G P P+ L    A T+  P     P +   
Sbjct: 963  GMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLP-GLAGTAGEPGRDGNPGSDGL 1021

Query: 1622 PSPEKGPATPAPKG---TPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP 1678
            P  +  P     +G   +P +P          P  PA  +   G + P    G P   G 
Sbjct: 1022 PGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGS 1081

Query: 1679 TALKEVLVAPAPESTPIITAPT-RKGPQTKKSSATSP-----PICPDPSAKNGSKGPLST 1732
                    AP P+        T  +G    K     P     P  P P+ + G+ G    
Sbjct: 1082 RG------APGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIG---- 1131

Query: 1733 VAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPP 1765
             +P P  P          GKD +    GP+ PP
Sbjct: 1132 -SPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPP 1163



 Score =  215 bits (547), Expect = 4e-55
 Identities = 330/1286 (25%), Positives = 408/1286 (31%), Gaps = 264/1286 (20%)

Query: 559  VLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSA 618
            V P    AP   P+ Q        P  P         G P   G P S    P G+  S 
Sbjct: 87   VCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSP--GPPGICESC 144

Query: 619  SVIKTDSYAGPDSAGPL-----LKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYT-TT 672
                     GP +  P      +KS +    +A +P  +  P    P    GTS +  + 
Sbjct: 145  PT-------GPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPP---GTSGHPGSP 194

Query: 673  ASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPK 732
             SP  +G     P   P + G        P+     P A  P             P  P 
Sbjct: 195  GSPGYQG-----PPGEPGQAG--------PSGPPGPPGAIGPSGPAGKDGESG-RPGRPG 240

Query: 733  SVPSPSLP----PAGTP--PGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGT 786
                P  P    PAG P  PG K   G    +               ++GA       G 
Sbjct: 241  ERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNG-----------EKGETGAPGLKGENG- 288

Query: 787  LTYLADSPSPLGVSVSPQTKRPPTKKGSAG---------------PDTPIGNLSSPVSP- 830
            L     +P P+G   +P  +  P   G+AG               P  P G    P SP 
Sbjct: 289  LPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPG 348

Query: 831  VEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSV 890
             +    P  S    GS  +P     P P    GA  P       P G+   P        
Sbjct: 349  AKGEVGPAGS---PGSNGAPGQRGEPGPQGHAGAQGPPG-----PPGINGSPGGKGEMGP 400

Query: 891  VNLP-----FPKEGPATPAPKQ-APALSMTSSSPKK--ARATPAPKG------IPASPSP 936
              +P         GP  PA    AP L   +  P K  A+  P P+G      IP  P  
Sbjct: 401  AGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGA 460

Query: 937  KGAPTPPAAT-PPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP---KGAPTPP--- 989
            KG      +   P   G P     + AP      P  P G P    P   +GAP P    
Sbjct: 461  KGEDGKDGSPGEPGANGLPGAAGERGAPG--FRGPAGPNGIPGEKGPAGERGAPGPAGPR 518

Query: 990  -AATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA 1048
             AA  P   G P  P  +G P  P       K  P  +    G   PP   P  P+G P 
Sbjct: 519  GAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPG--PSGPRGQPG 576

Query: 1049 AT--PLPKGAPTTPAATLPSPKGGPATPSLKGAP---------TPPAAT-PPSPKGGPAT 1096
                P PKG    P       +GGP  P  +G P          PP  T P   KG    
Sbjct: 577  VMGFPGPKGNDGAPGKN--GERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGP 634

Query: 1097 PSPKGAP-MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1155
            P P+G   +P    PP   G    P  KG    P A  P  KG    P  +G P    A 
Sbjct: 635  PGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGA--PGGKGDAGAPGERGPPGLAGA- 691

Query: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1215
             P  +GG   P P+G     AA PP P G   TP  +G         P  +GGL +P PK
Sbjct: 692  -PGLRGGAGPPGPEGG--KGAAGPPGPPGAAGTPGLQGM--------PGERGGLGSPGPK 740

Query: 1216 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLK 1275
            G    P    P   G      P+G PT P   PP P G P      GAP  P        
Sbjct: 741  GDKGEPGG--PGADGVPGKDGPRG-PTGPIG-PPGPAGQPGDKGEGGAPGLP-------- 788

Query: 1276 GGLATPPHKGAPNPAVVT-PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPT 1334
             G+A P  +G+P     T PP P G P      G         P  KG  G P  KG   
Sbjct: 789  -GIAGP--RGSPGERGETGPPGPAGFPGAPGQNG--------EPGGKGERGAPGEKGEGG 837

Query: 1335 PPAVT-PPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGP 1393
            PP V  PP   G    PA  P  +G      S  GP   A  P  +G P   PP     P
Sbjct: 838  PPGVAGPPGGSG----PAGPPGPQGVKGERGSPGGP-GAAGFPGARGLPG--PPGSNGNP 890

Query: 1394 AIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPK 1453
              P P G P          K  P  P    GA                    +P  S PK
Sbjct: 891  GPPGPSGSP---------GKDGPPGPAGNTGA------------------PGSPGVSGPK 923

Query: 1454 GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSP 1513
            G    P  KG P   A  PP    P     +  +      P  P P G+P    V   S 
Sbjct: 924  GDAGQPGEKGSP--GAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESG 981

Query: 1514 KEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK-----TPAIPTPK 1568
            K      S  R P  P                + L   A T   P +     +  +P   
Sbjct: 982  KPGANGLSGERGPPGP----------------QGLPGLAGTAGEPGRDGNPGSDGLPGRD 1025

Query: 1569 EAPATPSSK-EASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKG 1627
             +P     + E  SP A     + G P P    + PA  S    E+        P P   
Sbjct: 1026 GSPGGKGDRGENGSPGAPGAPGHPGPPGP----VGPAGKSGDRGESGPAGPAGAPGPAGS 1081

Query: 1628 PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVA 1687
               P P+G               P      T + GA   +  +G P   G          
Sbjct: 1082 RGAPGPQG---------------PRGDKGETGERGAAGIKGHRGFPGNPG---------- 1116

Query: 1688 PAPESTPIITAPTRKGPQTKKSSATSP-------PICPD-PSAKNGSKGPLSTVAPAPLL 1739
                      AP   GP  ++ +  SP       P+ P  P  K+G+ G      P P+ 
Sbjct: 1117 ----------APGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSG-----HPGPIG 1161

Query: 1740 PVQKDSSKTAKGKDASHSPKGPLAPP 1765
            P     ++  +G + S    G   PP
Sbjct: 1162 PPGPRGNRGERGSEGSPGHPGQPGPP 1187



 Score =  212 bits (540), Expect = 3e-54
 Identities = 265/1000 (26%), Positives = 312/1000 (31%), Gaps = 189/1000 (18%)

Query: 884  ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAP---------KGIPASP 934
            + P P +   PF +     P P  AP        P+  +  P P          GIP  P
Sbjct: 73   DCPNPEI---PFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQP 129

Query: 935  SPKGAPTPPAATPPSPKGGPATPSPKW--------------APTPPAATPPSPKGGPATP 980
               G+P PP      P  GP   SP++              A  P  A PP P G P T 
Sbjct: 130  GSPGSPGPPGICESCPT-GPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTS 188

Query: 981  SPKGAPTPPAATPPSPKGGPATPSPKGAPTPP-AVTPPSPKGSPAATPFPKGASTPPAAT 1039
               G+P  P      P G P    P G P PP A+ P  P G    +  P          
Sbjct: 189  GHPGSPGSPGY--QGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPG 246

Query: 1040 PPSPKGSPAATPLPKGAPTTPAAT-------LPSPKGGPATPSLKGAPTPPAAT-PPSPK 1091
            PP  KG       P G P  P              KG    P LKG    P     P P 
Sbjct: 247  PPGIKG-------PAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPM 299

Query: 1092 GGPATPSPKGAPMPPAAT----------------PPSPKGGLATPPHKGA--PTTPAATP 1133
            G    P  +G P  P A                 PP P G    P   GA     PA +P
Sbjct: 300  GPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSP 359

Query: 1134 PS--PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP--KGGLATP 1189
             S    G    P P+G     A  PP P G   +P  KG    PA  P +P   G    P
Sbjct: 360  GSNGAPGQRGEPGPQG--HAGAQGPPGPPGINGSPGGKG-EMGPAGIPGAPGLMGARGPP 416

Query: 1190 SPKGAPTTP----AATPPSPKGGLATPSPK------GAPTTPAATPPSPKGGLATPSPKG 1239
             P GA   P     A  P   G    P P+      G P  P A     K G  +P   G
Sbjct: 417  GPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDG--SPGEPG 474

Query: 1240 APTTPAAT----------PPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAP-N 1288
            A   P A           P  P G P    P G    P    P  +G    P   G P  
Sbjct: 475  ANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGP--RGAAGEPGRDGVPGG 532

Query: 1289 PAVVTPPSPKGGPAT----SPP-----KGAPTPPAATPPSPKGSPGT---PPPKGAPTPP 1336
            P +   P   GGP +     PP      G P PP   P  P+G PG    P PKG    P
Sbjct: 533  PGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPG--PSGPRGQPGVMGFPGPKGNDGAP 590

Query: 1337 AVT-------PPSPKGTPTLPATT-PSSKGGPTTPSSKEGPTPPAATPSHKGGPAM-TPP 1387
                       P P+G P     T P    GPT P   +G T P      +G P    PP
Sbjct: 591  GKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPP 650

Query: 1388 SPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPV-SLKKA 1446
                 P  P PKGD             AP  P  +  A  P  G+  PP +     L+  
Sbjct: 651  GENGKPGEPGPKGD-----------AGAPGAPGGKGDAGAP--GERGPPGLAGAPGLRGG 697

Query: 1447 PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP 1506
                 P+GG       G P   A   P  +  P  +    S  PK     P   GA  +P
Sbjct: 698  AGPPGPEGGKGAAGPPGPP--GAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVP 755

Query: 1507 AVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPT 1566
                   K+ P  P+    P  P      K      AP    I      P  +     P 
Sbjct: 756  G------KDGPRGPTGPIGPPGPAGQPGDKGEGG--APGLPGIAGPRGSPGERGETGPPG 807

Query: 1567 PKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPT-PPAVTPPSPE 1625
            P   P  P                +GAP  K    PP V  P     P  PP       E
Sbjct: 808  PAGFPGAPGQNGEPGGKG-----ERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGE 862

Query: 1626 KG----------------PATPAPKGTPTSPPVTPSSLKDSPTSPASVT---CKMGATVP 1666
            +G                P  P   G P  P  + S  KD P  PA  T      G + P
Sbjct: 863  RGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGP 922

Query: 1667 QASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGS 1726
            +   G P +KG         +P  +  P    P      T       PP  P P    G 
Sbjct: 923  KGDAGQPGEKG---------SPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGP 973

Query: 1727 KGPLSTVAPAPLLPVQKDSSKT-AKGKDASHSPKGPLAPP 1765
            +G            V+ +S K  A G      P GP   P
Sbjct: 974  QG------------VKGESGKPGANGLSGERGPPGPQGLP 1001



 Score =  196 bits (497), Expect = 3e-49
 Identities = 212/752 (28%), Positives = 256/752 (34%), Gaps = 123/752 (16%)

Query: 796  PLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHS 855
            P G +  P  K P  ++G+ GP  P G    P                 GS   P +   
Sbjct: 493  PAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPG--GPGMRGMPGSPGGPGSDGK 550

Query: 856  PTPPSPKG-APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT 914
            P PP  +G +  P    P  P+G          P V+  P PK     P           
Sbjct: 551  PGPPGSQGESGRPGPPGPSGPRG---------QPGVMGFPGPKGNDGAPG---------- 591

Query: 915  SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPS-PKGGPATPSPKWAP-TPPAATPPS 972
             +  +     P P+G P      G   PP  T P   KG    P P+     P    PP 
Sbjct: 592  KNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPG 651

Query: 973  PKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGA 1032
              G P  P PKG    P A  P  KG    P  +G        PP   G+P      +G 
Sbjct: 652  ENGKPGEPGPKGDAGAPGA--PGGKGDAGAPGERG--------PPGLAGAPGL----RGG 697

Query: 1033 STPPAATPPSPKGSPAATPLPKGAPTTPAAT-LPSPKGGPATPSLKGAPTPPAATPPSPK 1091
            + PP   P   KG+ A  P P GA  TP    +P  +GG  +P  KG    P    P   
Sbjct: 698  AGPPG--PEGGKGA-AGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGG--PGAD 752

Query: 1092 GGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPP--SP--KGGLATPPPKG 1147
            G P    P+G   P    PP P G        GAP  P    P  SP  +G    P P G
Sbjct: 753  GVPGKDGPRGPTGPIG--PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAG 810

Query: 1148 APTTPAAT-PPSPKGGLATPPPKGAPTTPA-ATPPSPKGGLATPSP------KGAPTTPA 1199
             P  P     P  KG    P  KG    P  A PP   G    P P      +G+P  P 
Sbjct: 811  FPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPG 870

Query: 1200 ATP-------PSPKGGLATPSPKGAPTTPAAT-PPSPKGGLATPSPKGAPTTPA-ATPPS 1250
            A         P P G    P P G   +P    PP P G    P   G       A  P 
Sbjct: 871  AAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPG 930

Query: 1251 PKGGPATPPPKGAPTPPAATPPSLKGGLATPPH----KGAPNPAVVT------------- 1293
             KG P    P GAP P      +   GLA PP     +G+P P  V              
Sbjct: 931  EKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSG 990

Query: 1294 ---PPSPKGGPATSPPKGAP----TPPAATPPSPKGSPG---------TPPPKGAPTPPA 1337
               PP P+G P  +   G P     P +   P   GSPG         +P   GAP  P 
Sbjct: 991  ERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPG 1050

Query: 1338 VTPPSPKGTPTLPATTPSSKG--GPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPA- 1394
              PP P G    PA     +G  GP  P+   GP      P  +G       + +RG A 
Sbjct: 1051 --PPGPVG----PAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAG 1104

Query: 1395 IPSPKGDPTSPAVIPLSPKKA----------PATPVTREGAATPSKGDLT---PPAVTPV 1441
            I   +G P +P   P SP  A          PA P    G + P   D T   P  + P 
Sbjct: 1105 IKGHRGFPGNPGA-PGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPP 1163

Query: 1442 SLKKAPATSAPKGGPATPSSKGDPTLPAVTPP 1473
              +        +G P  P   G P  P    P
Sbjct: 1164 GPRGNRGERGSEGSPGHPGQPGPPGPPGAPGP 1195



 Score =  156 bits (394), Expect = 2e-37
 Identities = 173/621 (27%), Positives = 206/621 (33%), Gaps = 112/621 (18%)

Query: 731  PKSVPSPSLPPAGT----PPGTKKVDGISHTSALAPVASSPKEC-PTEDSGASATASSKG 785
            P+  P P+ P        PPG + + G+  T         P E  P  D+GA      KG
Sbjct: 616  PQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKG 675

Query: 786  TLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGN--LSSPVSPVEASFLPENSLSF 843
                 A +P   G    P     P  +G AGP  P G    + P  P  A+  P      
Sbjct: 676  D----AGAPGERG---PPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTP----GL 724

Query: 844  QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSV--VNLPFPKEGPA 901
            QG         SP P   KG P         P    +P K+ P      +  P P   P 
Sbjct: 725  QGMPGERGGLGSPGPKGDKGEPG-------GPGADGVPGKDGPRGPTGPIGPPGPAGQPG 777

Query: 902  TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT-PPSPKGGPATPSPK 960
                  AP L   +      R +P  +G    P P G P  P     P  KG    P  K
Sbjct: 778  DKGEGGAPGLPGIAGP----RGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEK 833

Query: 961  WAPTPPAATPPSPKGGPATP-------SPKGAPTPPAAT----------PPSPKGGPATP 1003
                PP    P    GPA P         +G+P  P A           PP   G P  P
Sbjct: 834  GEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPP 893

Query: 1004 SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAP------ 1057
             P G+P      PP P G+  A   P  +     A  P  KGSP A   P GAP      
Sbjct: 894  GPSGSPGKDG--PPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQG-PPGAPGPLGIA 950

Query: 1058 -TTPAATL------PSPKGGPATPSLKGAPTPPAAT-------PPSPKGGPATPSPKGAP 1103
              T A  L      P P+G P    +KG    P A        PP P+G P      G P
Sbjct: 951  GITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEP 1010

Query: 1104 ----------MPPAATPPSPKGGLATPPHKGAPTTPAAT-PPSPKGGLATPPPKG--APT 1150
                      +P     P  KG        GAP  P    PP P G       +G   P 
Sbjct: 1011 GRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPA 1070

Query: 1151 TPAATPPSPKGGLATPPPKGAPTTPAAT----PPSPKGGLATPSPKGAPTTPAATPPSPK 1206
             PA  P  P G    P P+G       T        KG    P   GAP +P   P   +
Sbjct: 1071 GPAGAP-GPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPG--PAGQQ 1127

Query: 1207 GGLATPSPKG--APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG---------GP 1255
            G + +P P G   P  P+  PP   G    P P G        PP P+G          P
Sbjct: 1128 GAIGSPGPAGPRGPVGPSG-PPGKDGTSGHPGPIG--------PPGPRGNRGERGSEGSP 1178

Query: 1256 ATPPPKGAPTPPAATPPSLKG 1276
              P   G P PP A  P   G
Sbjct: 1179 GHPGQPGPPGPPGAPGPCCGG 1199



 Score =  142 bits (359), Expect = 3e-33
 Identities = 164/601 (27%), Positives = 191/601 (31%), Gaps = 90/601 (14%)

Query: 702  PTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGI-SHTSAL 760
            P      P  P P+           AP  P        P    PPG     G+       
Sbjct: 649  PPGENGKPGEPGPKGDAG-------APGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPP 701

Query: 761  APVASSPKECPTEDSGASATASSKGTLTYLADSPSP-----LGVSVSPQTKRPPTKKGSA 815
             P        P    GA+ T   +G         SP      G    P     P K G  
Sbjct: 702  GPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPR 761

Query: 816  GPDTPIGNLSSPVSPVE-----ASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP-TPSA 869
            GP  PIG       P +     A  LP       G + SP       PP P G P  P  
Sbjct: 762  GPTGPIGPPGPAGQPGDKGEGGAPGLP----GIAGPRGSPGERGETGPPGPAGFPGAPGQ 817

Query: 870  VTPLSPKGVTLPPKETPT--PSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAP 927
                  KG    P E     P  V  P    GPA P   Q           K  R +P  
Sbjct: 818  NGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGV---------KGERGSPGG 868

Query: 928  KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPT 987
             G    P  +G P PP +      G P  P P  +P      PP P G    P   G   
Sbjct: 869  PGAAGFPGARGLPGPPGS-----NGNPGPPGPSGSPGKDG--PPGPAGNTGAPGSPGVSG 921

Query: 988  PPA-ATPPSPKGGPATPSPKGAPTPPAVT-------------PPSPKGSPAATPFPKGAS 1033
            P   A  P  KG P    P GAP P  +               P P+GSP      KG S
Sbjct: 922  PKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGV-KGES 980

Query: 1034 TPPAATPPSPKGSPAATPLPKGAP-TTPAATLPSPKGGPATPSLKGAP-TPPAATPPSPK 1091
              P A   S +  P   P P+G P     A  P   G P +  L G   +P         
Sbjct: 981  GKPGANGLSGERGP---PGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGEN 1037

Query: 1092 GGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151
            G P  P   G P PP    P+ K G      +  P  PA   P P G    P P+G    
Sbjct: 1038 GSPGAPGAPGHPGPPGPVGPAGKSG---DRGESGPAGPAGA-PGPAGSRGAPGPQGPRGD 1093

Query: 1152 PAAT----PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKG--APTTPAATPPSP 1205
               T        KG    P   GAP +P   P   +G + +P P G   P  P+  PP  
Sbjct: 1094 KGETGERGAAGIKGHRGFPGNPGAPGSPG--PAGQQGAIGSPGPAGPRGPVGPSG-PPGK 1150

Query: 1206 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265
             G    P P G        PP P+G       +G+P  P        G P  P P GAP 
Sbjct: 1151 DGTSGHPGPIG--------PPGPRGNRGERGSEGSPGHP--------GQPGPPGPPGAPG 1194

Query: 1266 P 1266
            P
Sbjct: 1195 P 1195



 Score =  137 bits (345), Expect = 1e-31
 Identities = 199/775 (25%), Positives = 242/775 (31%), Gaps = 107/775 (13%)

Query: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG 1139
            P PP A P  P  G     PKG P PP    P   G    P   G+P +P   PP    G
Sbjct: 89   PQPPTA-PTRPPNGQGPQGPKGDPGPPGI--PGRNGDPGIPGQPGSPGSPG--PP----G 139

Query: 1140 LATPPPKGAPT-TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198
            +    P G    +P       K G+A     G P    A PP P G   T    G+P +P
Sbjct: 140  ICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGP--AGPPGPPGPPGTSGHPGSPGSP 197

Query: 1199 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL-------ATPSPKGAPTTPAATPPSP 1251
                P  + G A PS  G P  P A  PS   G          P  +G P  P    P+ 
Sbjct: 198  GYQGPPGEPGQAGPS--GPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPA- 254

Query: 1252 KGGPATPPPKGAP-------TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS 1304
             G P  P  KG                P LKG    P   GAP P       P+G P   
Sbjct: 255  -GIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPM-----GPRGAPGER 308

Query: 1305 PPKGAPTPPAATP-PSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTL-PATTPSSKGGPTT 1362
               G P    A      +GS G P P G P   A  P SP     + PA +P S G P  
Sbjct: 309  GRPGLPGAAGARGNDGARGSDGQPGPPGPPGT-AGFPGSPGAKGEVGPAGSPGSNGAPGQ 367

Query: 1363 -----PSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI----PLSPK 1413
                 P    G   P   P   G P         G     P G P +P ++    P  P 
Sbjct: 368  RGEPGPQGHAGAQGPPGPPGINGSPG--------GKGEMGPAGIPGAPGLMGARGPPGPA 419

Query: 1414 KAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG---PATPSSKGDPTLPAV 1470
             A   P  R GA  P K             K  P     +G    P  P +KG+      
Sbjct: 420  GANGAPGLRGGAGEPGKN----------GAKGEPGPRGERGEAGIPGVPGAKGEDGKDG- 468

Query: 1471 TPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPT 1530
               SP EP A   +  ++  + AP    P G   +P       ++ PA       P  P 
Sbjct: 469  ---SPGEPGA-NGLPGAAGERGAPGFRGPAGPNGIPG------EKGPAGERGAPGPAGPR 518

Query: 1531 ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590
                     A   P    +P    +     +P  P     P  P S+  S  P       
Sbjct: 519  G--------AAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRP------- 563

Query: 1591 KGAPSPKELLIPPAVTS-PSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKD 1649
             G P P      P V   P PK     P         GP  P P+G P     T      
Sbjct: 564  -GPPGPSGPRGQPGVMGFPGPKGNDGAPGKN--GERGGPGGPGPQGPPGKNGETGPQGPP 620

Query: 1650 SPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPE-STPIITAPTRKGPQTKK 1708
             PT P       G   PQ  +GLP   GP         P P+       AP  KG     
Sbjct: 621  GPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAP 680

Query: 1709 SSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESK 1768
                 P +   P  + G+  P          P     +    G       +G L  P  K
Sbjct: 681  GERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPK 740

Query: 1769 ASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGL 1823
                      E   P  +       P  P   P+ P P P   P  +    +PGL
Sbjct: 741  GDKG------EPGGPGADGVPGKDGPRGPTG-PIGP-PGPAGQPGDKGEGGAPGL 787



 Score =  102 bits (253), Expect = 5e-21
 Identities = 185/739 (25%), Positives = 232/739 (31%), Gaps = 108/739 (14%)

Query: 1232 LATPSPKGAPTTPAATPPSPKGGPATPP-------PKGAPTPPAAT----PPSLKGGLAT 1280
            L  P+P+       A  P P   P  PP       PKG P PP        P + G   +
Sbjct: 72   LDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGS 131

Query: 1281 PPHKGAPNPAVVTPPSP------------KGGPATSPPKGAPTPPAATPPSPKGSPGTPP 1328
            P   G P      P  P            K G A     G P P  A PP P G PGT  
Sbjct: 132  PGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGP--AGPPGPPGPPGTSG 189

Query: 1329 PKGAPTPPAVTPPSPKGTPTLPATTPSSKG--GPTTPSSKEGPTPPAATPSHKG------ 1380
              G+P  P    P  +     P+  P   G  GP+ P+ K+G +     P  +G      
Sbjct: 190  HPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPG 249

Query: 1381 --GPAMTPPSP--------------KRGPAIPSPKGDPTSP----AVIPLSPKKAP---- 1416
              GPA  P  P              K     P  KG+   P    A  P+ P+ AP    
Sbjct: 250  IKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERG 309

Query: 1417 ------ATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG--GPA-TPSSKGDPTL 1467
                  A        A  S G   PP   P      P +   KG  GPA +P S G P  
Sbjct: 310  RPGLPGAAGARGNDGARGSDGQPGPPG--PPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQ 367

Query: 1468 PAVTPP----SPKEPPAPKQVATS------SSPKKAPATPAPMGAPTLPAVIPSSPKEVP 1517
                 P      + PP P  +  S        P   P  P  MGA   P   P+     P
Sbjct: 368  RGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPG--PAGANGAP 425

Query: 1518 ATPSSRRDPIAPTATLLSKKTPATLAPK-EALIPPAMTVPSPKKTPAIPTPKEAPATP-S 1575
                   +P    A    K  P     + EA IP              P    A   P +
Sbjct: 426  GLRGGAGEPGKNGA----KGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGA 481

Query: 1576 SKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKG 1635
            + E  +P    P+   G P  K     PA    +P  A    A   P  +  P  P  +G
Sbjct: 482  AGERGAPGFRGPAGPNGIPGEK----GPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRG 537

Query: 1636 TPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPI 1695
             P SP    S  K  P      + + G   P   +G P   G    K    AP       
Sbjct: 538  MPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGER- 596

Query: 1696 ITAPTRKGPQ--TKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAK-GK 1752
               P   GPQ    K+  T P   P P+   G KG      P  L  +        + GK
Sbjct: 597  -GGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGK 655

Query: 1753 DASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESA-SVSAAPSPPVSLPLAPSPVPTLP 1811
                 PKG    P +        A  E+  P    A  +     PP       +  P  P
Sbjct: 656  PGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGP 715

Query: 1812 PKQQFLPSSPGLVLE--SPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAG 1869
            P     P   G+  E      P    D+ E     P  P + GVP +    + P   +  
Sbjct: 716  PGAAGTPGLQGMPGERGGLGSPGPKGDKGE-----PGGPGADGVPGK----DGPRGPTGP 766

Query: 1870 IPVPTPSAKQPVTKNNKGS 1888
            I  P P A QP  K   G+
Sbjct: 767  IGPPGP-AGQPGDKGEGGA 784



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 121/504 (24%), Positives = 155/504 (30%), Gaps = 53/504 (10%)

Query: 536  PASLEGAPFSPAQAGLTTKKDPT--VLPLVQAAPKNSPSFQSTSSSPEIP--LSPEATLA 591
            P   +G P  P   G+  K  P     P+    P   P  +    +P +P    P  +  
Sbjct: 739  PKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPG 798

Query: 592  KKS-LGEPLPIGKPASSMTS--PLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPT-VAA 647
            ++   G P P G P +   +  P G     +  +      P  AGP   S    P     
Sbjct: 799  ERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQG 858

Query: 648  FPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSL-APKNHPVKEGTLTTLPLVPTASE 706
               E   P G  P  A           P   G      P   P K+G     P  P  + 
Sbjct: 859  VKGERGSPGG--PGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDG-----PPGPAGNT 911

Query: 707  NCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALA--PVA 764
              P +P       P        E  K  P    PP    PG   + GI+    LA  P  
Sbjct: 912  GAPGSPG---VSGPKGDAGQPGE--KGSPGAQGPPGA--PGPLGIAGITGARGLAGPPGM 964

Query: 765  SSPKECPTEDS--GASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIG 822
              P+  P      G S    + G L+     P P G+     T   P + G+ G D   G
Sbjct: 965  PGPRGSPGPQGVKGESGKPGANG-LSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPG 1023

Query: 823  NLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPP 882
               SP                 G K       SP  P   G P P    P+ P G +   
Sbjct: 1024 RDGSP-----------------GGKGDRGENGSPGAPGAPGHPGPPG--PVGPAGKSGDR 1064

Query: 883  KETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP 942
             E+        P P      P P Q P      +  + A      +G P +P   G+P P
Sbjct: 1065 GESGPAGPAGAPGPAGSRGAPGP-QGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGP 1123

Query: 943  PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP-SPKGGPA 1001
                      GPA P     P  P+  PP   G    P P G P P         +G P 
Sbjct: 1124 AGQQGAIGSPGPAGPR---GPVGPSG-PPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPG 1179

Query: 1002 TPSPKGAPTPPAVTPPSPKGSPAA 1025
             P   G P PP    P   G  AA
Sbjct: 1180 HPGQPGPPGPPGAPGPCCGGVGAA 1203



 Score = 32.3 bits (72), Expect = 5.0
 Identities = 43/171 (25%), Positives = 54/171 (31%), Gaps = 29/171 (16%)

Query: 37   ALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTA 96
            A G PGP  P P  PA +      +  A P  +P    S     P PQ   G     G  
Sbjct: 1045 APGHPGP--PGPVGPAGKSGDRGESGPAGPAGAPGPAGSRG--APGPQGPRGDKGETGER 1100

Query: 97   PEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALA-PHSVQKSSAFPP 155
              A   +    G P +P A     P       G+P  + P   V  + P     +S  P 
Sbjct: 1101 GAAG--IKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHP- 1157

Query: 156  NLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPP 206
                                  PI P  P+ N  +  SE  P   G P PP
Sbjct: 1158 ---------------------GPIGPPGPRGNRGERGSEGSPGHPGQPGPP 1187


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  238 bits (608), Expect = 3e-62
 Identities = 358/1386 (25%), Positives = 432/1386 (31%), Gaps = 262/1386 (18%)

Query: 706  ENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVAS 765
            +  P  P P+    P       P  P +   P +P     PG + + G + T        
Sbjct: 80   DGIPGPPGPKGIRGPPGL----PGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPG 135

Query: 766  SPK----ECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDT-- 819
            SP     + P    G        G++  ++  P P G   +P    PP  +G  GP    
Sbjct: 136  SPGFPGLQGPPGPPGIPGMKGEPGSII-MSSLPGPKG---NPGYPGPPGIQGLPGPTGIP 191

Query: 820  -PIGNLSSP--VSPVEASFLP----ENSLSFQGSKDSPATTHSPTPPSPKGAPT------ 866
             PIG    P  + P     LP       L+FQG K          PP P G  +      
Sbjct: 192  GPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPI 251

Query: 867  -----------PSAVTPLSPKGVTLPPK----ETPTPSVVNLPFPKEGPATPAPKQAPAL 911
                       P    P  P G+  PP     E         P  +  P        P +
Sbjct: 252  DVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGI 311

Query: 912  SMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPP 971
                  P      P   G        G P PP    P P  G           P      
Sbjct: 312  PGLPGDPGYP-GEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEK 370

Query: 972  SPKGGPATPSPKGAPTPPAAT---PPSPKGGPATPSPKGAPTPPAVT---PPSPKGSPAA 1025
              +G P    P G P PP A    PP P G P     KG   PP ++   PP   G P A
Sbjct: 371  GERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGA 430

Query: 1026 -----TPFPKGASTPPA-----ATPPSPKGSPAATPL----------------------- 1052
                  P P G   PP+       PP P GSP    L                       
Sbjct: 431  PGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGIS 490

Query: 1053 -PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAA--- 1108
             P G P  P   LP P G    P  KG      AT   PKG P  P   GAP  P +   
Sbjct: 491  GPPGQPGLPG--LPGPPGSLGFPGQKGEKGQAGAT--GPKGLPGIPGAPGAPGFPGSKGE 546

Query: 1109 -----TPPSPKGGLATPPHKGAPTTPA--ATP--------PSPK---GGLATPPPKGAPT 1150
                 T P  KG        GAP  P    TP        P PK   GG+     +G P 
Sbjct: 547  PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606

Query: 1151 TPAAT---------------PPSPKG-----GLA-------TPPPKGAPTTPAATP---- 1179
             P                  PP P G     G+A        P PKG P      P    
Sbjct: 607  NPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG 666

Query: 1180 ----PSPKGGLATPSPKGAPTTPAAT------------------PPSPKGGLATPSPKGA 1217
                P   G +  P   G P  P                     PP PKG    P P GA
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726

Query: 1218 PTTPAAT----PPSPKG--------GLATPSPKGAPTTP----AATPPSPKGGPATPPP- 1260
            P TP       PP P G        G A P P G P  P    A  P   +G P  P P 
Sbjct: 727  PGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPP 786

Query: 1261 -----KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG--GPATSP-------P 1306
                  G P P     P+ + G   PP  G P   V  PP P G  GP   P        
Sbjct: 787  GRTGLDGLPGPKGDVGPNGQPGPMGPP--GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGE 844

Query: 1307 KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS-- 1364
            KG P PP    P P G  G+P   GAP P  + PP   G+P LP    +S G P T    
Sbjct: 845  KGDPGPPGLDVPGPPGERGSPGIPGAPGP--IGPP---GSPGLPGKAGAS-GFPGTKGEM 898

Query: 1365 ---SKEGPTPPAATPSHKGGPAMTPPSPKRG-PAIPSPKGDPTSPAVIPLSPKKAPATPV 1420
                  GP  P   P   G P +      +G P +P P G+  S     L     P  P 
Sbjct: 899  GMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL-----PGPPG 953

Query: 1421 TREGAATPSKGDLTPPAVTPVSLKKAPATSAPK------GGPATPSSKGDPTLPAVTPPS 1474
              +     SKG+   P +  +     P  S PK      G P  P   G P LP   PP 
Sbjct: 954  PMDPNLLGSKGEKGEPGLPGI-----PGVSGPKGYQGLPGDPGQPGLSGQPGLPG--PPG 1006

Query: 1475 PK-EPPAPKQVATSSSPKKAPAT-----PAPMG--APTLPAVIPSSPKEVPATPSSRRDP 1526
            PK  P  P Q      P           P P G   P  P+ +P  P   P  P  + D 
Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGS-PGLPGQKGDK 1065

Query: 1527 IAPTATLLSKKTPATLAPK-EALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV 1585
              P  + +    P    PK E  +P     P  K +   P     P TP +K     P  
Sbjct: 1066 GDPGISSIG--LPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF 1123

Query: 1586 TPSTYKGAPSPKELLIPPA----VTSPSPKEAPTPPAVTPPSPEKG----PATPAPKGTP 1637
             P T  G P PK +  PP        P P      P    P  EKG       P P G  
Sbjct: 1124 -PGT-PGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQK 1181

Query: 1638 TSPPVTPSSLKDSPTSPASVTCKMGATVP--QASKGLPAKKGPTALKEVLVAPAPESTPI 1695
              P          P  P     K    +P    + GLP  KG            P   P 
Sbjct: 1182 GEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG 1241

Query: 1696 ITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDAS 1755
               P  +GP+        PP  P P+   G  GP       P LP     +   KG+  +
Sbjct: 1242 SPGPALEGPK-GNPGPQGPPGRPGPTGFQGLPGP----EGPPGLP----GNGGIKGEKGN 1292

Query: 1756 HSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQ 1815
                G    P  K          +    +P    +   P  P          P+  P   
Sbjct: 1293 PGQPGLPGLPGLKGDQ--GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA 1350

Query: 1816 FLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKS-AGIPVPT 1874
                 PGL+   P  P  P    + + +I  +    G+P Q  L  +P P+   G+P PT
Sbjct: 1351 GPEGEPGLI-GPPGPPGLPGPSGQSI-IIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPT 1408

Query: 1875 PSAKQP 1880
                 P
Sbjct: 1409 GPPGDP 1414



 Score =  228 bits (580), Expect = 6e-59
 Identities = 315/1190 (26%), Positives = 373/1190 (31%), Gaps = 202/1190 (16%)

Query: 709  PVAPSPQNTCAPLATLVLAPEIPKSVPSP------SLPPAGTPPGTKKVDGISHTSALA- 761
            P    P     P    V+ P  P   P          PP  + PG   +DG      L  
Sbjct: 376  PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435

Query: 762  -PVASSPKECPTED---------SGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTK 811
             P  + P   P+++          G+      +G      D        +      PP +
Sbjct: 436  PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 812  KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT 871
             G  G   P G+L  P    E       +   +G    P    +P  P  KG P      
Sbjct: 496  PGLPGLPGPPGSLGFPGQKGEKG--QAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTF 553

Query: 872  P--LSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKG 929
            P     KG    P     P +   P     P  P PK  P       + K  R  P   G
Sbjct: 554  PGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPG----GITFKGERGPPGNPG 609

Query: 930  IPASPSPKGAPTPPAATPPSP------------KGGPATPSPKWAPTPPAATP------- 970
            +P  P   G   PP   PP P             G P  P PK  P      P       
Sbjct: 610  LPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 971  ----------------PSPKGGPATPSPKGAPTPPAAT---PPSPKGGPATPSPKGAP-T 1010
                            P   G P  P  KG P  P      PP PKG P  P P GAP T
Sbjct: 670  NPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGT 729

Query: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA-----------ATPLPKGAP-T 1058
            P  +    P G P   P PKG        PP P G P              P P G P  
Sbjct: 730  PGRIGLEGPPG-PPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGR 788

Query: 1059 TPAATLPSPKG--------GPATP------SLKGAPTPPAATPPSPKGGP---ATPSPKG 1101
            T    LP PKG        GP  P       ++G P PP    P P G P     P  KG
Sbjct: 789  TGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI--PGPIGQPGLHGIPGEKG 846

Query: 1102 APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT------ 1155
             P PP    P P G   +P   GAP      P  P G    P   GA   P         
Sbjct: 847  DPGPPGLDVPGPPGERGSPGIPGAP-----GPIGPPGSPGLPGKAGASGFPGTKGEMGMM 901

Query: 1156 -PPSPKGGLATPPPKGAPTTPAATP-------PSPKGGLATPSPKGAPTTPAATPPSPKG 1207
             PP P G L  P   G P              P P G   +    G P  P    P+  G
Sbjct: 902  GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLG 961

Query: 1208 GLATPSPKGAPTTPAATPPSPKGGL----ATPSPKGAPTTPAATPPSPKGGPATPPPKGA 1263
                    G P  P  + P    GL      P   G P  P   PP PKG P  P     
Sbjct: 962  SKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG--PPGPKGNPGLP----- 1014

Query: 1264 PTPPAATPPSLKGGLATPPHKGAPNP-AVVTPPSPKGGPATSPPKGAPTPPAATPP---S 1319
              P    PP LKG   T    G P P  V  PP P G P      G P           S
Sbjct: 1015 GQPGLIGPPGLKG---TIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGIS 1071

Query: 1320 PKGSPGTPPPKGAPTPPAVTPPSP--------KGTPTLPATTPSSKGGPTTPSSKEGPTP 1371
              G PG P PKG P  P   P +P         G P LP  TP +KG P  P     P P
Sbjct: 1072 SIGLPGLPGPKGEPGLPGY-PGNPGIKGSVGDPGLPGLPG-TPGAKGQPGLPGFPGTPGP 1129

Query: 1372 PAATPSHKGGPAMTP-----PSPKRG---PAIPSPKGDPTSPAVIPLSPKKAPATPVTRE 1423
            P   P    GP   P     P P  G   P  P P G+   P          P     + 
Sbjct: 1130 PG--PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKP-----GQDGIPGPAGQKG 1182

Query: 1424 GAATPSKGDLTPPAVTPVSLKKAP-ATSAPKGGPATPSSKGDP---TLPAVT-PPSPKEP 1478
                P  G+  PP +  +S +K         G P  P  KG+P     P V  PP P   
Sbjct: 1183 EPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS 1242

Query: 1479 PAPKQVATSSS--PKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSK 1536
            P P       +  P+  P  P P G   LP   P  P  +P     + +   P    L  
Sbjct: 1243 PGPALEGPKGNPGPQGPPGRPGPTGFQGLPG--PEGPPGLPGNGGIKGEKGNPGQPGL-- 1298

Query: 1537 KTPATLAPKEALIPPAMT-------VPSPKKTPAIPTPKEAPAT--PSSKEASSPPAVTP 1587
              P     K    PP +        +   K  P +P     P    PS    S+ P   P
Sbjct: 1299 --PGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEP 1356

Query: 1588 STYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGT--PTSPPVTPS 1645
                G P P  L  P   +     +A  P     P  +  P    P+G   PT PP  P 
Sbjct: 1357 GLI-GPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPG 1415

Query: 1646 SLKDSPTSPASVTCKMGATVP--QASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKG 1703
                 P    +   K    +P    ++GL    GP  L+       P   P  ++     
Sbjct: 1416 R-NGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQ------GPPGPPGTSSVAHGF 1468

Query: 1704 PQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKD 1753
              T+ S  T  P CP        +G L       LL VQ   +K A G+D
Sbjct: 1469 LITRHSQTTDAPQCP--------QGTLQVYEGFSLLYVQ--GNKRAHGQD 1508



 Score =  212 bits (539), Expect = 3e-54
 Identities = 290/1066 (27%), Positives = 339/1066 (31%), Gaps = 156/1066 (14%)

Query: 918  PKKARATPAPKGIPASPSPKGAPTPPAATP-PSPKGGPATPSPKWAPTP---PAATPPSP 973
            P   R      GIP  P PKG   PP     P   G P  P    AP P   P       
Sbjct: 70   PPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKG 129

Query: 974  K----GGPATPSPKGAPTPPAATPPSPKGGPAT------PSPKGAPTPPAVTPPSPKGSP 1023
            +    G P  P  +G P PP    P  KG P +      P PKG P  P   PP  +G P
Sbjct: 130  ERGFPGSPGFPGLQGPPGPPGI--PGMKGEPGSIIMSSLPGPKGNPGYPG--PPGIQGLP 185

Query: 1024 AAT--PFPKGASTPPAAT-PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP 1080
              T  P P G   PP    PP P G P     PKG           PKG      L+G P
Sbjct: 186  GPTGIPGPIGPPGPPGLMGPPGPPGLPG----PKG---NMGLNFQGPKGEKGEQGLQGPP 238

Query: 1081 TPPAATPPS--------PKGGPATPSPKGAPMPPAAT-PPSPKGGLATPPHKGAPTTPAA 1131
             PP               KG    P  +G P PP    PP P GG      KG    P  
Sbjct: 239  GPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGG--EKGEKGEQGEPGK 296

Query: 1132 T-PPSPKGGLATPPPKGAPTTPA-ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1189
               P   G    P   G P  P     P   G        G P  P    P P  G+ T 
Sbjct: 297  RGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGI-TI 355

Query: 1190 SPKGAPTTPAATPPSPKGGLATP---SPKGAPTTPAAT---PPSPKGGLATPSPKGAPTT 1243
              KG    P    P  KG    P    P G P  P A    PP P G       KG    
Sbjct: 356  GEKGNIGLPGL--PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGP 413

Query: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG---- 1299
            P  + P P G    P   G P PP    P +      PP      P    PP   G    
Sbjct: 414  PGISIPGPPGLDGQPGAPGLPGPPGPAGPHI------PPSDEICEPGPPGPPGSPGDKGL 467

Query: 1300 ------------------GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341
                              G   S P G P  P    P P GS G P  KG       T  
Sbjct: 468  QGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGL--PGPPGSLGFPGQKGEKGQAGAT-- 523

Query: 1342 SPKGTPTLPATT-----PSSKGGP----TTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392
             PKG P +P        P SKG P    T P  K G      +P   G P + P +P + 
Sbjct: 524  GPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMK-GDKGELGSPGAPGLPGL-PGTPGQD 581

Query: 1393 --PAIPSPKGDPTSPAVI-PLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT 1449
              P +P PKG+P          P   P  P               PP   PV  K     
Sbjct: 582  GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG--PVGEKGIQGV 639

Query: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP--------KKAPATPAPMG 1501
            +   G P  P  KGDP      P  P  P  P +      P           P  P   G
Sbjct: 640  AGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKG 699

Query: 1502 APTLPAV---IPSSPKEVPATPSSRRDPIAPTATLLS--KKTPATLAPKEALIPPAMTVP 1556
             P +P +    P  PK  P  P     P  P    L      P    PK     P   +P
Sbjct: 700  EPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG---EPGFALP 756

Query: 1557 SPKKTPAIPTPKEAPATPSSKEASSPPAVTPST-YKGAPSPK---------ELLIPPAVT 1606
             P   P +P  K A      +    PP     T   G P PK           + PP + 
Sbjct: 757  GPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816

Query: 1607 SPSPKEAPTPPAVTPPSPEKG-PATPAPKGTPTSPPVT---PSSLKDSPTSPASVTCKMG 1662
                +  P PP +  P  + G    P  KG P  P +    P   + SP  P +     G
Sbjct: 817  GIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGA----PG 872

Query: 1663 ATVPQASKGLPAKKG----PTALKEVLVAPAPESTPIITAPTRKGPQTKK--SSATSPPI 1716
               P  S GLP K G    P    E+ +   P     +  P R G    K        P 
Sbjct: 873  PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG 932

Query: 1717 CPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAA 1776
             P P+ + GSKG      P   +      SK  KG+       G   P            
Sbjct: 933  LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP-----------K 981

Query: 1777 AFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGL--VLESPSKPLAP 1834
             ++ +   P    +S  P  P   P  P   P L P Q  L   PGL   +     P   
Sbjct: 982  GYQGLPGDPGQPGLSGQPGLPG--PPGPKGNPGL-PGQPGLIGPPGLKGTIGDMGFPGPQ 1038

Query: 1835 ADEDELLPL-IPPEPISGGVPFQSVLVNMPTPKSAGIP-VPTPSAK 1878
              E    P  +P +P S G+P Q      P   S G+P +P P  +
Sbjct: 1039 GVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE 1084


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score =  238 bits (606), Expect = 6e-62
 Identities = 179/519 (34%), Positives = 253/519 (48%), Gaps = 70/519 (13%)

Query: 901  ATPAPKQAPALSMTSSSPKKARATPA----PKGIPASPSPKGAPTPPAATPPSPKGGPAT 956
            + P+P    + +MT   P    ATPA       + +  +P  A   P+A   +    P  
Sbjct: 1505 SAPSPMGGISPAMT---PWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGY 1561

Query: 957  PSPKWAPTPPAATPPSPKGGPATPSPKGA------PTPPAATPPSPKGGPATPSPKGAPT 1010
             SP W+PTP +   P P   P  PSP GA      PT PA  P SP GG    SP  +PT
Sbjct: 1562 -SPAWSPTPGSPGSPGPSS-PYIPSPGGAMSPSYSPTSPAYEPRSP-GGYTPQSPSYSPT 1618

Query: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG 1070
             P+ +P SP  SP +   P  + T P+ +P SP  SP +   P  +PT+P+ +  SP   
Sbjct: 1619 SPSYSPTSPSYSPTS---PNYSPTSPSYSPTSPSYSPTS---PSYSPTSPSYSPTSPSYS 1672

Query: 1071 PATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPA 1130
            P +PS   +PT P+ +P SP   P +PS   +P  P+ +P SP     +P +  +PT+P+
Sbjct: 1673 PTSPSY--SPTSPSYSPTSPSYSPTSPSY--SPTSPSYSPTSPSYSPTSPSY--SPTSPS 1726

Query: 1131 ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS 1190
             +P SP           +PT+P+ +P SP           +PT+P  TP SP    +  S
Sbjct: 1727 YSPTSPSY---------SPTSPSYSPTSPNY---------SPTSPNYTPTSPS--YSPTS 1766

Query: 1191 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1250
            P  +PT+P  TP SP    +  SP  +PT+P+ +P SP    +  SP+  P +P  TP S
Sbjct: 1767 PSYSPTSPNYTPTSPN--YSPTSPSYSPTSPSYSPTSPS--YSPSSPRYTPQSPTYTPSS 1822

Query: 1251 PKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP 1310
            P   P++P    +PT P  TP S     ++P +   P     +P SPK  P +  PK +P
Sbjct: 1823 PSYSPSSP--SYSPTSPKYTPTSPSYSPSSPEY--TPTSPKYSPTSPKYSPTS--PKYSP 1876

Query: 1311 TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPT 1370
            T P  +P +PK SP +  P  +PT P  TP SPK +PT P  +P+        S K  PT
Sbjct: 1877 TSPTYSPTTPKYSPTS--PTYSPTSPVYTPTSPKYSPTSPTYSPT--------SPKYSPT 1926

Query: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIP 1409
             P  +P+   G   +P SP   P   SP    TSPA+ P
Sbjct: 1927 SPTYSPTSPKGSTYSPTSPGYSPT--SPTYSLTSPAISP 1963



 Score =  235 bits (599), Expect = 4e-61
 Identities = 181/543 (33%), Positives = 260/543 (47%), Gaps = 62/543 (11%)

Query: 904  APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963
            A K    + + ++ P    A P      ++PSP G  +P A TP +    PA  +  W+P
Sbjct: 1477 AEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISP-AMTPWNQGATPAYGA--WSP 1533

Query: 964  TPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023
            +  +   P    G A  SP  A      +P        TP   G+P P +   PSP G+ 
Sbjct: 1534 SVGSGMTP----GAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAM 1589

Query: 1024 AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPP 1083
            +    P  + T PA  P SP G    +P    +PT+P+ +  SP   P +P+   +PT P
Sbjct: 1590 S----PSYSPTSPAYEPRSPGGYTPQSP--SYSPTSPSYSPTSPSYSPTSPNY--SPTSP 1641

Query: 1084 AATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATP 1143
            + +P SP   P +PS   +P  P+ +P SP     +P +  +PT+P+ +P SP       
Sbjct: 1642 SYSPTSPSYSPTSPSY--SPTSPSYSPTSPSYSPTSPSY--SPTSPSYSPTSPSY----- 1692

Query: 1144 PPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1203
                +PT+P+ +P SP           +PT+P+ +P SP    +  SP  +PT+P+ +P 
Sbjct: 1693 ----SPTSPSYSPTSPSY---------SPTSPSYSPTSPS--YSPTSPSYSPTSPSYSPT 1737

Query: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGA 1263
            SP    +  SP  +PT+P  TP SP    +  SP  +PT+P  TP SP   P +P    +
Sbjct: 1738 SPS--YSPTSPNYSPTSPNYTPTSPS--YSPTSPSYSPTSPNYTPTSPNYSPTSP--SYS 1791

Query: 1264 PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS 1323
            PT P+ +P S     ++P +   P     TP SP   P  S P  +PT P  TP SP  S
Sbjct: 1792 PTSPSYSPTSPSYSPSSPRY--TPQSPTYTPSSPSYSP--SSPSYSPTSPKYTPTSPSYS 1847

Query: 1324 PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKG-GPTTPSSKEGPTPPAATPSHKGGP 1382
            P +P  +  PT P  +P SPK +PT P  +P+S    PTTP  K  PT P  +P+    P
Sbjct: 1848 PSSP--EYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTP--KYSPTSPTYSPT---SP 1900

Query: 1383 AMTPPSPKRGPAIP-----SPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPA 1437
              TP SPK  P  P     SPK  PTSP   P SPK +  +P +   + T     LT PA
Sbjct: 1901 VYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPA 1960

Query: 1438 VTP 1440
            ++P
Sbjct: 1961 ISP 1963



 Score =  224 bits (570), Expect = 9e-58
 Identities = 189/524 (36%), Positives = 259/524 (49%), Gaps = 78/524 (14%)

Query: 1031 GASTPPA---ATPPSPKG--SPAATPLPKGAPTTPAATLPSPK-GGPATPSLKGAPTPPA 1084
            GA+ P      + PSP G  SPA TP  +GA  TPA    SP  G   TP   G  +P A
Sbjct: 1494 GAAGPTGMFFGSAPSPMGGISPAMTPWNQGA--TPAYGAWSPSVGSGMTPGAAGF-SPSA 1550

Query: 1085 ATPPS---PKGGPA---TPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138
            A+  S   P   PA   TP   G+P P +   PSP GG  +P +  +PT+PA  P SP G
Sbjct: 1551 ASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSP-GGAMSPSY--SPTSPAYEPRSP-G 1606

Query: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198
            G     P  +PT+P+ +P SP    +   P  +PT+P+ +P SP    +  SP  +PT+P
Sbjct: 1607 GYTPQSPSYSPTSPSYSPTSPS--YSPTSPNYSPTSPSYSPTSPS--YSPTSPSYSPTSP 1662

Query: 1199 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATP 1258
            + +P SP    +  SP  +PT+P+ +P SP    +  SP  +PT+P+ +P SP   P +P
Sbjct: 1663 SYSPTSPS--YSPTSPSYSPTSPSYSPTSPS--YSPTSPSYSPTSPSYSPTSPSYSPTSP 1718

Query: 1259 P-----PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPP 1313
                  P  +PT P+ +P S      +P +  +P     TP SP   P +  P  +PT P
Sbjct: 1719 SYSPTSPSYSPTSPSYSPTSPSYSPTSPNY--SPTSPNYTPTSPSYSPTS--PSYSPTSP 1774

Query: 1314 AATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT-TPSSKEGPTPP 1372
              TP SP  SP +P    +PT P+ +P SP  +P+ P  TP S   PT TPSS      P
Sbjct: 1775 NYTPTSPNYSPTSP--SYSPTSPSYSPTSPSYSPSSPRYTPQS---PTYTPSS------P 1823

Query: 1373 AATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432
            + +PS    P+ +P SPK  P   SP   P+SP   P SPK +P +P          K  
Sbjct: 1824 SYSPS---SPSYSPTSPKYTPT--SPSYSPSSPEYTPTSPKYSPTSP----------KYS 1868

Query: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKK 1492
             T P  +P S   +P T  PK  P +P+    PT P  TP SPK  P        +SP  
Sbjct: 1869 PTSPKYSPTSPTYSPTT--PKYSPTSPTY--SPTSPVYTPTSPKYSP--------TSPTY 1916

Query: 1493 APATPAPMGAPTLPAVIPSSPKEVPATPSS-RRDPIAPTATLLS 1535
            +P   +P  +PT P   P+SPK    +P+S    P +PT +L S
Sbjct: 1917 SPT--SPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTS 1958



 Score =  192 bits (488), Expect = 3e-48
 Identities = 149/459 (32%), Positives = 211/459 (45%), Gaps = 64/459 (13%)

Query: 776  GASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPI-----GNLSSPVSP 830
            G+  T  + G     A   S      SP     P   GS GP +P      G +S   SP
Sbjct: 1536 GSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSP 1595

Query: 831  VEASFLPENSLSF--QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTP 888
               ++ P +   +  Q    SP T+ S +P SP  +PT    +P SP      P  +PT 
Sbjct: 1596 TSPAYEPRSPGGYTPQSPSYSP-TSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTS 1654

Query: 889  SVVNLPFPKEGPATPA-PKQAPALSMTSSSPKKARATPAPKGIPASP-SPKGAPTPPAAT 946
               +   P   P +P+    +P+ S TS S      + +P     SP SP  +PT P+ +
Sbjct: 1655 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1714

Query: 947  PPSPKGGPATPS-----PKWAPTPPAATPPSPKGGPATP-----SPKGAPTPPAATPPSP 996
            P SP   P +PS     P ++PT P+ +P SP   P +P     SP  +PT P+ +P SP
Sbjct: 1715 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSP 1774

Query: 997  KGGPATP-----SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATP 1051
               P +P     SP  +PT P+ +P SP  SP++   P+     P  TP SP  SP++  
Sbjct: 1775 NYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSS---PRYTPQSPTYTPSSPSYSPSSPS 1831

Query: 1052 L----PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPA 1107
                 PK  PT+P+ +  SP+  P +P  K +PT P  +P SPK  P   SP  +P  P 
Sbjct: 1832 YSPTSPKYTPTSPSYSPSSPEYTPTSP--KYSPTSPKYSPTSPKYSPT--SPTYSPTTPK 1887

Query: 1108 ATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP 1167
             +P SP           +PT+P  TP S         PK +PT+P  +P S         
Sbjct: 1888 YSPTSP---------TYSPTSPVYTPTS---------PKYSPTSPTYSPTS--------- 1920

Query: 1168 PKGAPTTPAATPPSPKGGLATP-SPKGAPTTPAATPPSP 1205
            PK +PT+P  +P SPKG   +P SP  +PT+P  +  SP
Sbjct: 1921 PKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSP 1959



 Score =  189 bits (481), Expect = 2e-47
 Identities = 173/521 (33%), Positives = 240/521 (46%), Gaps = 66/521 (12%)

Query: 1226 PSPKGGLATPSPKGAPTTPAATPPSPKGG--PA-TPPPKGAPTPPAATPPSLKGGLATPP 1282
            P+   GL    P G     A   PSP GG  PA TP  +GA     A  PS+  G+    
Sbjct: 1487 PTNIPGLGAAGPTGMFFGSA---PSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGA 1543

Query: 1283 HKGAPNPAV-VTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341
               +P+ A   +  SP   PA SP  G+P  P  + P      G   P  +PT PA  P 
Sbjct: 1544 AGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPR 1603

Query: 1342 SPKG-TPTLPATTPSSKG-GPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP--- 1396
            SP G TP  P+ +P+S    PT+PS    PT P  +P+    P+ +P SP   P  P   
Sbjct: 1604 SPGGYTPQSPSYSPTSPSYSPTSPS--YSPTSPNYSPT---SPSYSPTSPSYSPTSPSYS 1658

Query: 1397 --SPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG 1454
              SP   PTSP+  P SP  +P +P     + T      T P+ +P S   +P  ++P  
Sbjct: 1659 PTSPSYSPTSPSYSPTSPSYSPTSP---SYSPTSPSYSPTSPSYSPTSPSYSP--TSPSY 1713

Query: 1455 GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATP-----APMGAPTLPAVI 1509
             P +PS    PT P+ +P SP   P      + +SP  +P +P     +P  +PT P+  
Sbjct: 1714 SPTSPSY--SPTSPSYSPTSPSYSPTSPSY-SPTSPNYSPTSPNYTPTSPSYSPTSPSYS 1770

Query: 1510 PSSPKEVPATPSSRRDPIAPTATLLSKKTP--ATLAPKEALIPPAMTVPSPKKTPAIPTP 1567
            P+SP   P +P+      +PT+   S  +P  +  +P  +   P  T  SP  TP+  +P
Sbjct: 1771 PTSPNYTPTSPN-----YSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPS--SP 1823

Query: 1568 KEAPATPSSKEASSPPAVTPSTYKGAP-SPKELLIPPAVTSPSPKEAPTPPAVTPPSPEK 1626
              +P++PS    S  P  TP++   +P SP+     P  +  SPK +PT P  +P SP  
Sbjct: 1824 SYSPSSPSYSPTS--PKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTY 1881

Query: 1627 GPATP-----APKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTAL 1681
             P TP     +P  +PTSP  TP+S K SPTSP         T P+ S   P    PT+ 
Sbjct: 1882 SPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPT-----YSPTSPKYSPTSPT-YSPTSP 1935

Query: 1682 KEVLVAP-APESTPIITAPTRKGPQTKKSSATSPPICPDPS 1721
            K    +P +P  +P  T+PT         S TSP I PD S
Sbjct: 1936 KGSTYSPTSPGYSP--TSPT--------YSLTSPAISPDDS 1966



 Score =  164 bits (414), Expect = 1e-39
 Identities = 139/422 (32%), Positives = 189/422 (44%), Gaps = 57/422 (13%)

Query: 736  SPSLPPAGTP-PGTKKVDGISHTSALAPV-ASSPKECPTEDSGASATASSKGTLTYLADS 793
            SP   PA +P PG+    G S     +P  A SP   PT  +       S G  T  + S
Sbjct: 1558 SPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPA---YEPRSPGGYTPQSPS 1614

Query: 794  PSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSP-VSPVEASFLPENSLSFQGSKDSPAT 852
             SP   S SP +        +  P +P  + +SP  SP   S+ P +      S     T
Sbjct: 1615 YSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1674

Query: 853  THSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPA-PKQAPAL 911
            + S +P SP  +PT  + +P SP      P  +PT    +   P   P +P+    +P+ 
Sbjct: 1675 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1734

Query: 912  SMTSSS--PKKARATP-APKGIPASPS-----PKGAPTPPAATPPSPKGGPATPS----- 958
            S TS S  P     +P +P   P SPS     P  +PT P  TP SP   P +PS     
Sbjct: 1735 SPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTS 1794

Query: 959  PKWAPTPPAATPPSPKGGPATP------------SPKGAPTPPAATPPSPKGGPATP--- 1003
            P ++PT P+ +P SP+  P +P            SP  +PT P  TP SP   P++P   
Sbjct: 1795 PSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYT 1854

Query: 1004 --SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPA 1061
              SPK +PT P  +P SPK SP          T P  +P +PK SP +   P  +PT+P 
Sbjct: 1855 PTSPKYSPTSPKYSPTSPKYSP----------TSPTYSPTTPKYSPTS---PTYSPTSPV 1901

Query: 1062 ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG---APMPPAATPPSPKGGLA 1118
             T  SPK  P +P+   +PT P  +P SP   P   SPKG   +P  P  +P SP   L 
Sbjct: 1902 YTPTSPKYSPTSPTY--SPTSPKYSPTSPTYSPT--SPKGSTYSPTSPGYSPTSPTYSLT 1957

Query: 1119 TP 1120
            +P
Sbjct: 1958 SP 1959



 Score =  160 bits (405), Expect = 1e-38
 Identities = 160/529 (30%), Positives = 221/529 (41%), Gaps = 44/529 (8%)

Query: 562  LVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVI 621
            L Q AP  +  F     + +     E       LG   P G    S  SP+G  S A   
Sbjct: 1460 LGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTP 1519

Query: 622  KTDSYAGPDSAGPLLKSSLITPTVAAF-PLESADPAGVAPTTAKGTSTYTTTASPFLEGT 680
                      A      S +TP  A F P  ++D +G +P  +   S   T  SP   G+
Sbjct: 1520 WNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSP--TPGSP---GS 1574

Query: 681  VSLAPKNHPVKEGTLTTL--PLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVP-SP 737
               +    P   G ++    P  P      P   +PQ+      +   +P  P   P SP
Sbjct: 1575 PGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSP 1634

Query: 738  SLPPAGTPPGTKKVDGISHTS-ALAPVASSPKECPTEDSGASATASSKGTL-TYLADSPS 795
            +  P  +P  +      S TS + +P  +SP   PT  S +  + S   T  +Y   SPS
Sbjct: 1635 NYSPT-SPSYSPTSPSYSPTSPSYSP--TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1691

Query: 796  --PLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSP-VSPVEASFLPENSLSFQGSKDSPAT 852
              P   S SP +        S  P +P  + +SP  SP   S+ P +      S +   T
Sbjct: 1692 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPT 1751

Query: 853  THSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALS 912
            + + TP SP  +PT  + +P SP      P  +PT    +   P   P +P         
Sbjct: 1752 SPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSP--------- 1802

Query: 913  MTSSSPKKARATP-APKGIPASPS-----PKGAPTPPAATPPSPKGGPATPSPKWAPTPP 966
              S SP   R TP +P   P+SPS     P  +PT P  TP SP   P+  SP++ PT P
Sbjct: 1803 --SYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPS--SPEYTPTSP 1858

Query: 967  AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026
              +P SPK  P   SPK +PT P  +P +PK  P   SP  +PT P  TP SPK SP + 
Sbjct: 1859 KYSPTSPKYSPT--SPKYSPTSPTYSPTTPKYSPT--SPTYSPTSPVYTPTSPKYSPTSP 1914

Query: 1027 PF----PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGP 1071
             +    PK + T P  +P SPKGS  +   P  +PT+P  +L SP   P
Sbjct: 1915 TYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISP 1963



 Score =  158 bits (400), Expect = 5e-38
 Identities = 161/562 (28%), Positives = 234/562 (41%), Gaps = 103/562 (18%)

Query: 1301 PATSPPKGAPTPPA---ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK 1357
            P   P  GA  P      + PSP G             PA+TP +   TP   A +PS  
Sbjct: 1487 PTNIPGLGAAGPTGMFFGSAPSPMGG----------ISPAMTPWNQGATPAYGAWSPSVG 1536

Query: 1358 GGPTTPSSKEGPTPPAATPSHKGGPAMTPP-SPKRG---------PAIPSPKGDPTSPAV 1407
             G T  ++  G +P AA+ +    P  +P  SP  G         P IPSP G   SP+ 
Sbjct: 1537 SGMTPGAA--GFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSP-GGAMSPSY 1593

Query: 1408 IPLSPKKAPATPVTREGAATPSKGDLTP--PAVTPVSLKKAPATSAPKGGPATPSSKGDP 1465
             P SP   P +P    G  TP     +P  P+ +P S   +P  ++P   P +PS    P
Sbjct: 1594 SPTSPAYEPRSP----GGYTPQSPSYSPTSPSYSPTSPSYSP--TSPNYSPTSPSYS--P 1645

Query: 1466 TLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRD 1525
            T P+ +P SP   P     + +S P  +P +P+   +PT P+  P+SP   P +PS    
Sbjct: 1646 TSPSYSPTSPSYSPTSPSYSPTS-PSYSPTSPSY--SPTSPSYSPTSPSYSPTSPS---- 1698

Query: 1526 PIAPTATLLSKKTPA--TLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPP 1583
              +PT+   S  +P+    +P  +   P+ +  SP  +P   +P  +P +P+    S  P
Sbjct: 1699 -YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT--SPSYSPTSPNYSPTS--P 1753

Query: 1584 AVTPSTYKGAP-SPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPA-----PKGTP 1637
              TP++   +P SP      P  T  SP  +PT P+ +P SP   P +P+     P+ TP
Sbjct: 1754 NYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTP 1813

Query: 1638 TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697
             SP  TPSS   SP+SP+        T P+ +   P+              +PE TP  T
Sbjct: 1814 QSPTYTPSSPSYSPSSPS-----YSPTSPKYTPTSPSYS----------PSSPEYTP--T 1856

Query: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757
            +P +  P + K S TSP   P                          +S T       +S
Sbjct: 1857 SP-KYSPTSPKYSPTSPKYSP--------------------------TSPTYSPTTPKYS 1889

Query: 1758 PKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFL 1817
            P  P   P S   TP T+  +    P     S   +P+ P   P +P      P    + 
Sbjct: 1890 PTSPTYSPTSPVYTP-TSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYS 1948

Query: 1818 PSSPGLVLESPSKPLAPADEDE 1839
            P+SP   L SP+  ++P D DE
Sbjct: 1949 PTSPTYSLTSPA--ISPDDSDE 1968



 Score =  120 bits (302), Expect = 1e-26
 Identities = 132/490 (26%), Positives = 201/490 (41%), Gaps = 42/490 (8%)

Query: 1424 GAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ 1483
            G+A    G ++P A+TP +    PA  A    P+  S         +TP +    P+   
Sbjct: 1504 GSAPSPMGGISP-AMTPWNQGATPAYGA--WSPSVGSG--------MTPGAAGFSPSAAS 1552

Query: 1484 VATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLA 1543
             A+  SP  +PA     G+P  P   PSSP  +P+   +     +PT+     ++P    
Sbjct: 1553 DASGFSPGYSPAWSPTPGSPGSPG--PSSPY-IPSPGGAMSPSYSPTSPAYEPRSPGGYT 1609

Query: 1544 PKEALIPPAMTVPSPKKTPAIPT-PKEAPATPSSKEASSPPAVTPSTYKGAP-SPKELLI 1601
            P+     P     SP      PT P  +P +PS    S  P+ +P++   +P SP     
Sbjct: 1610 PQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTS--PSYSPTSPSYSPTSPSYSPT 1667

Query: 1602 PPAVTSPSPKEAPTPPAVTPPSPEKGPATP-----APKGTPTSPPVTPSSLKDSPTSP-- 1654
             P+ +  SP  +PT P+ +P SP   P +P     +P  +PTSP  +P+S   SPTSP  
Sbjct: 1668 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1727

Query: 1655 ASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKG--PQTKKSSAT 1712
            +  +     T P  S   P    PT+      +P+   T    +PT     P +   S T
Sbjct: 1728 SPTSPSYSPTSPSYSPTSP-NYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPT 1786

Query: 1713 SP---PICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKA 1769
            SP   P  P  S  + S  P S+    P  P    SS +      S+SP  P   P S +
Sbjct: 1787 SPSYSPTSPSYSPTSPSYSP-SSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPS 1845

Query: 1770 STPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPS 1829
             +P ++  +    PK    S   +P+ P   P +P+  PT P   ++ P+SP     SP+
Sbjct: 1846 YSP-SSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTP---KYSPTSP---TYSPT 1898

Query: 1830 KPLAPADEDELLPLIPP-EPISGGVPFQSVLVNMPTPKSAGIPVPTP--SAKQPVTKNNK 1886
             P+      +  P  P   P S      S   +  +PK +     +P  S   P      
Sbjct: 1899 SPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTS 1958

Query: 1887 GSGTESDSDE 1896
             + +  DSDE
Sbjct: 1959 PAISPDDSDE 1968



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 136/526 (25%), Positives = 189/526 (35%), Gaps = 63/526 (11%)

Query: 98   EAPTFLPNL--IGPP-----ISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKS 150
            E PT +P L   GP       +P+ +   SP + P  +G        A  A    S    
Sbjct: 1485 EIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQG--------ATPAYGAWSPSVG 1536

Query: 151  SAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVS 210
            S   P      PS A   SG     S   +P+          S  +P+P G  SP     
Sbjct: 1537 SGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPS---- 1592

Query: 211  TVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPV 270
               Y   +P    +S     PQ          SP    T+ S    SP +P S S   P 
Sbjct: 1593 ---YSPTSPAYEPRSPGGYTPQ----------SPSYSPTSPS---YSPTSP-SYSPTSPN 1635

Query: 271  SPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPS- 329
              P + S S  S P  + +  +  P +P   P S     +P   S   +      T PS 
Sbjct: 1636 YSPTSPSYSPTS-PSYSPTSPSYSPTSPSYSPTS--PSYSPTSPSYSPTSPSYSPTSPSY 1692

Query: 330  ALSDPTVKTISVDHSSTGASY-PSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTI 388
            + + P+    S  +S T  SY P+  S  P  PS +   P+     P  +P+        
Sbjct: 1693 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT-------- 1744

Query: 389  SSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVV-TNPC 447
             S   SP+      TS S SPT+     +SPN T   P  +    S   T+P    T+P 
Sbjct: 1745 -SPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPS 1803

Query: 448  TIAAAPTTTFEVATCVSPPMSSGPIS-NIEPTSPAALVMAP-VAPKEPSTQVATTLRIPV 505
               ++P  T +  T      S  P S +  PTSP     +P  +P  P     +    P 
Sbjct: 1804 YSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPT 1863

Query: 506  SPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQA 565
            SP    P   K  P+S      T K   T P     +P SP     + K  PT       
Sbjct: 1864 SPKY-SPTSPKYSPTSPTYSPTTPKYSPTSPTY---SPTSPVYTPTSPKYSPTSPTYSPT 1919

Query: 566  APKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSP 611
            +PK SP+  + S     P SP+ +    +     P   P  S+TSP
Sbjct: 1920 SPKYSPTSPTYS-----PTSPKGSTYSPTSPGYSPT-SPTYSLTSP 1959



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 108/436 (24%), Positives = 162/436 (37%), Gaps = 41/436 (9%)

Query: 464  SPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVL 523
            SP  S  P S   P   +  + +P     PS    +    P SP    P+     P+S  
Sbjct: 1562 SPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPS 1621

Query: 524  VKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIP 583
               PT       P S   +P SP+ +  +    PT       +P  SP+  S S     P
Sbjct: 1622 YS-PTSPSYS--PTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS-----P 1673

Query: 584  LSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITP 643
             SP  +    S     P   P S   SP    +S S   T     P S      S   +P
Sbjct: 1674 TSPSYSPTSPSYSPTSPSYSPTSPSYSP----TSPSYSPTSPSYSPTSPSYSPTSPSYSP 1729

Query: 644  TVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPT 703
            T  ++   S   +  +P  +  +  YT T+  +   + S +P +      T T+    PT
Sbjct: 1730 TSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTS---PNYTPTSPNYSPT 1786

Query: 704  ASENCPVAPS--PQNTCAPLATLVLAPEIPKSVPS-PSLPPAGTPPGTKKVDGISHTSAL 760
            +    P +PS  P +     ++    P+ P   PS PS  P+              + + 
Sbjct: 1787 SPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSY 1846

Query: 761  APVASSPKECPTEDSGASATASSKGTLTYLADSP--SPLGVSVSPQTKRPPTKKGSAGPD 818
            +P  SSP+  PT    +  +        Y   SP  SP   + SP T +      +  P 
Sbjct: 1847 SP--SSPEYTPTSPKYSPTSPK------YSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPT 1898

Query: 819  TPIGNLSSP-VSPVEASFLPENSLSFQGSKDSPAT-THSPTPPSPKGA---PTPSAVTPL 873
            +P+   +SP  SP   ++ P +       K SP + T+SPT  SPKG+   PT    +P 
Sbjct: 1899 SPVYTPTSPKYSPTSPTYSPTSP------KYSPTSPTYSPT--SPKGSTYSPTSPGYSPT 1950

Query: 874  SPKGVTLPPKETPTPS 889
            SP      P  +P  S
Sbjct: 1951 SPTYSLTSPAISPDDS 1966


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  237 bits (604), Expect = 1e-61
 Identities = 358/1382 (25%), Positives = 436/1382 (31%), Gaps = 260/1382 (18%)

Query: 706  ENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVAS 765
            +  P  P P+    P       P  P +   P +P     PG + + G + T        
Sbjct: 80   DGIPGPPGPKGIRGPPGL----PGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPG 135

Query: 766  SPK----ECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDT-- 819
            SP     + P    G        G++  ++  P P G   +P    PP  +G  GP    
Sbjct: 136  SPGFPGLQGPPGPPGIPGMKGEPGSII-MSSLPGPKG---NPGYPGPPGIQGLPGPTGIP 191

Query: 820  -PIGNLSSP--VSPVEASFLP----ENSLSFQGSKDSPATTHSPTPPSPKGAPT------ 866
             PIG    P  + P     LP       L+FQG K          PP P G  +      
Sbjct: 192  GPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPI 251

Query: 867  -----------PSAVTPLSPKGVTLPPK----ETPTPSVVNLPFPKEGPATPAPKQAPAL 911
                       P    P  P G+  PP     E         P  +  P        P +
Sbjct: 252  DVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGI 311

Query: 912  SMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPP 971
                  P      P   G        G P PP    P P  G           P      
Sbjct: 312  PGLPGDPGYP-GEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEK 370

Query: 972  SPKGGPATPSPKGAPTPPAAT---PPSPKGGPATPSPKGAPTPPAVT---PPSPKGSPAA 1025
              +G P    P G P PP A    PP P G P     KG   PP ++   PP   G P A
Sbjct: 371  GERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGA 430

Query: 1026 -----TPFPKGASTPPA-----ATPPSPKGSPAATPL----------------------- 1052
                  P P G   PP+       PP P GSP    L                       
Sbjct: 431  PGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGIS 490

Query: 1053 -PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAA--- 1108
             P G P  P   LP P G    P  KG      AT   PKG P  P   GAP  P +   
Sbjct: 491  GPPGQPGLPG--LPGPPGSLGFPGQKGEKGQAGAT--GPKGLPGIPGAPGAPGFPGSKGE 546

Query: 1109 -----TPPSPKGGLATPPHKGAPTTPA--ATP--------PSPK---GGLATPPPKGAPT 1150
                 T P  KG        GAP  P    TP        P PK   GG+     +G P 
Sbjct: 547  PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606

Query: 1151 TPAAT---------------PPSPKG-----GLA-------TPPPKGAPTTPAATP---- 1179
             P                  PP P G     G+A        P PKG P      P    
Sbjct: 607  NPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG 666

Query: 1180 ----PSPKGGLATPSPKGAPTTPAAT------------------PPSPKGGLATPSPKGA 1217
                P   G +  P   G P  P                     PP PKG    P P GA
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726

Query: 1218 PTTPAAT----PPSPKG--------GLATPSPKGAPTTP----AATPPSPKGGPATPPP- 1260
            P TP       PP P G        G A P P G P  P    A  P   +G P  P P 
Sbjct: 727  PGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPP 786

Query: 1261 -----KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG--GPATSP-------P 1306
                  G P P     P+ + G   PP  G P   V  PP P G  GP   P        
Sbjct: 787  GRTGLDGLPGPKGDVGPNGQPGPMGPP--GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGE 844

Query: 1307 KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS-- 1364
            KG P PP    P P G  G+P   GAP P  + PP   G+P LP    +S G P T    
Sbjct: 845  KGDPGPPGLDVPGPPGERGSPGIPGAPGP--IGPP---GSPGLPGKAGAS-GFPGTKGEM 898

Query: 1365 ---SKEGPTPPAATPSHKGGPAMTPPSPKRG-PAIPSPKGDPTSPAVIPLSPKKAPATPV 1420
                  GP  P   P   G P +      +G P +P P G+  S     L     P  P 
Sbjct: 899  GMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL-----PGPPG 953

Query: 1421 TREGAATPSKGDLTPPAVTPVSLKKAPATSAPK------GGPATPSSKGDPTLPAVTPPS 1474
              +     SKG+   P +  +     P  S PK      G P  P   G P LP   PP 
Sbjct: 954  PMDPNLLGSKGEKGEPGLPGI-----PGVSGPKGYQGLPGDPGQPGLSGQPGLPG--PPG 1006

Query: 1475 PK-EPPAPKQVATSSSPKKAPAT-----PAPMG--APTLPAVIPSSPKEVPATPSSRRDP 1526
            PK  P  P Q      P           P P G   P  P+ +P  P   P  P  + D 
Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGS-PGLPGQKGDK 1065

Query: 1527 IAPTATLLSKKTPATLAPK-EALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV 1585
              P  + +    P    PK E  +P     P  K +   P     P TP +K     P  
Sbjct: 1066 GDPGISSIG--LPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF 1123

Query: 1586 TPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVT-P 1644
             P T  G P PK +  PP   +P     P P        + GP  P  KG P    +  P
Sbjct: 1124 -PGT-PGPPGPKGISGPPG--NPGLPGEPGPVGGGGHPGQPGP--PGEKGKPGQDGIPGP 1177

Query: 1645 SSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEV---LVAPAPESTPIITA-PT 1700
            +  K  P  P       G   P    GL  +KG   L  +      P P+  P     P 
Sbjct: 1178 AGQKGEPGQPG-----FGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG 1232

Query: 1701 RKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVA-PAPLLPVQKDSSKTAKGKDASHSPK 1759
             +GP     S    P    P    G +GP      P P  P     +   KG+  +    
Sbjct: 1233 VQGPPGPPGS--PGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQP 1290

Query: 1760 GPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPS 1819
            G    P  K          +    +P    +   P  P          P+  P       
Sbjct: 1291 GLPGLPGLKGDQ--GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEG 1348

Query: 1820 SPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKS-AGIPVPTPSAK 1878
             PGL+   P  P  P    + + +I  +    G+P Q  L  +P P+   G+P PT    
Sbjct: 1349 EPGLI-GPPGPPGLPGPSGQSI-IIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPG 1406

Query: 1879 QP 1880
             P
Sbjct: 1407 DP 1408



 Score =  229 bits (584), Expect = 2e-59
 Identities = 316/1188 (26%), Positives = 372/1188 (31%), Gaps = 204/1188 (17%)

Query: 709  PVAPSPQNTCAPLATLVLAPEIPKSVPSP------SLPPAGTPPGTKKVDGISHTSALA- 761
            P    P     P    V+ P  P   P          PP  + PG   +DG      L  
Sbjct: 376  PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435

Query: 762  -PVASSPKECPTED---------SGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTK 811
             P  + P   P+++          G+      +G      D        +      PP +
Sbjct: 436  PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 812  KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT 871
             G  G   P G+L  P    E       +   +G    P    +P  P  KG P      
Sbjct: 496  PGLPGLPGPPGSLGFPGQKGEKG--QAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTF 553

Query: 872  P--LSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKG 929
            P     KG    P     P +   P     P  P PK  P       + K  R  P   G
Sbjct: 554  PGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPG----GITFKGERGPPGNPG 609

Query: 930  IPASPSPKGAPTPPAATPPSP------------KGGPATPSPKWAPTPPAATP------- 970
            +P  P   G   PP   PP P             G P  P PK  P      P       
Sbjct: 610  LPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 971  ----------------PSPKGGPATPSPKGAPTPPAAT---PPSPKGGPATPSPKGAP-T 1010
                            P   G P  P  KG P  P      PP PKG P  P P GAP T
Sbjct: 670  NPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGT 729

Query: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA-----------ATPLPKGAP-T 1058
            P  +    P G P   P PKG        PP P G P              P P G P  
Sbjct: 730  PGRIGLEGPPG-PPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGR 788

Query: 1059 TPAATLPSPKG--------GPATP------SLKGAPTPPAATPPSPKGGP---ATPSPKG 1101
            T    LP PKG        GP  P       ++G P PP    P P G P     P  KG
Sbjct: 789  TGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI--PGPIGQPGLHGIPGEKG 846

Query: 1102 APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT------ 1155
             P PP    P P G   +P   GAP      P  P G    P   GA   P         
Sbjct: 847  DPGPPGLDVPGPPGERGSPGIPGAP-----GPIGPPGSPGLPGKAGASGFPGTKGEMGMM 901

Query: 1156 -PPSPKGGLATPPPKGAPTTPAATP-------PSPKGGLATPSPKGAPTTPAATPPSPKG 1207
             PP P G L  P   G P              P P G   +    G P  P    P+  G
Sbjct: 902  GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLG 961

Query: 1208 GLATPSPKGAPTTPAATPPSPKGGL----ATPSPKGAPTTPAATPPSPKGGPATPPPKGA 1263
                    G P  P  + P    GL      P   G P  P   PP PKG P  P     
Sbjct: 962  SKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG--PPGPKGNPGLP----- 1014

Query: 1264 PTPPAATPPSLKGGLATPPHKGAPNP-AVVTPPSPKGGPATSPPKGAPTPPAATPP---S 1319
              P    PP LKG   T    G P P  V  PP P G P      G P           S
Sbjct: 1015 GQPGLIGPPGLKG---TIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGIS 1071

Query: 1320 PKGSPGTPPPKGAPTPPAVTPPSP--------KGTPTLPATTPSSKGGPTTPSSKEGPTP 1371
              G PG P PKG P  P   P +P         G P LP  TP +KG P  P     P P
Sbjct: 1072 SIGLPGLPGPKGEPGLPGY-PGNPGIKGSVGDPGLPGLPG-TPGAKGQPGLPGFPGTPGP 1129

Query: 1372 PAATPSHKGGPAMTP-----PSPKRG---PAIPSPKGDPTSPAVIPLSPKKAPATPVTRE 1423
            P   P    GP   P     P P  G   P  P P G+   P          P     + 
Sbjct: 1130 PG--PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKP-----GQDGIPGPAGQKG 1182

Query: 1424 GAATPSKGDLTPPAVTPVSLKKAP-ATSAPKGGPATPSSKGDP---TLPAVT-PPSPKEP 1478
                P  G+  PP +  +S +K         G P  P  KG+P     P V  PP P   
Sbjct: 1183 EPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS 1242

Query: 1479 PAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKT 1538
            P P        PK  P    P G P LP   P  P  +P     + +   P    L    
Sbjct: 1243 PGP----ALEGPKGNPGPQGPPGRPGLPG--PEGPPGLPGNGGIKGEKGNPGQPGL---- 1292

Query: 1539 PATLAPKEALIPPAMT-------VPSPKKTPAIPTPKEAPAT--PSSKEASSPPAVTPST 1589
            P     K    PP +        +   K  P +P     P    PS    S+ P   P  
Sbjct: 1293 PGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL 1352

Query: 1590 YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGT--PTSPPVTPSSL 1647
              G P P  L  P   +     +A  P     P  +  P    P+G   PT PP  P   
Sbjct: 1353 I-GPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGR- 1410

Query: 1648 KDSPTSPASVTCKMGATVP--QASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQ 1705
               P    +   K    +P    ++GL    GP  L+       P   P  ++       
Sbjct: 1411 NGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQ------GPPGPPGTSSVAHGFLI 1464

Query: 1706 TKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKD 1753
            T+ S  T  P CP        +G L       LL VQ   +K A G+D
Sbjct: 1465 TRHSQTTDAPQCP--------QGTLQVYEGFSLLYVQ--GNKRAHGQD 1502



 Score =  212 bits (539), Expect = 3e-54
 Identities = 290/1066 (27%), Positives = 339/1066 (31%), Gaps = 156/1066 (14%)

Query: 918  PKKARATPAPKGIPASPSPKGAPTPPAATP-PSPKGGPATPSPKWAPTP---PAATPPSP 973
            P   R      GIP  P PKG   PP     P   G P  P    AP P   P       
Sbjct: 70   PPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKG 129

Query: 974  K----GGPATPSPKGAPTPPAATPPSPKGGPAT------PSPKGAPTPPAVTPPSPKGSP 1023
            +    G P  P  +G P PP    P  KG P +      P PKG P  P   PP  +G P
Sbjct: 130  ERGFPGSPGFPGLQGPPGPPGI--PGMKGEPGSIIMSSLPGPKGNPGYPG--PPGIQGLP 185

Query: 1024 AAT--PFPKGASTPPAAT-PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP 1080
              T  P P G   PP    PP P G P     PKG           PKG      L+G P
Sbjct: 186  GPTGIPGPIGPPGPPGLMGPPGPPGLPG----PKG---NMGLNFQGPKGEKGEQGLQGPP 238

Query: 1081 TPPAATPPS--------PKGGPATPSPKGAPMPPAAT-PPSPKGGLATPPHKGAPTTPAA 1131
             PP               KG    P  +G P PP    PP P GG      KG    P  
Sbjct: 239  GPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGG--EKGEKGEQGEPGK 296

Query: 1132 T-PPSPKGGLATPPPKGAPTTPA-ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1189
               P   G    P   G P  P     P   G        G P  P    P P  G+ T 
Sbjct: 297  RGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGI-TI 355

Query: 1190 SPKGAPTTPAATPPSPKGGLATP---SPKGAPTTPAAT---PPSPKGGLATPSPKGAPTT 1243
              KG    P    P  KG    P    P G P  P A    PP P G       KG    
Sbjct: 356  GEKGNIGLPGL--PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGP 413

Query: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG---- 1299
            P  + P P G    P   G P PP    P +      PP      P    PP   G    
Sbjct: 414  PGISIPGPPGLDGQPGAPGLPGPPGPAGPHI------PPSDEICEPGPPGPPGSPGDKGL 467

Query: 1300 ------------------GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341
                              G   S P G P  P    P P GS G P  KG       T  
Sbjct: 468  QGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGL--PGPPGSLGFPGQKGEKGQAGAT-- 523

Query: 1342 SPKGTPTLPATT-----PSSKGGP----TTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392
             PKG P +P        P SKG P    T P  K G      +P   G P + P +P + 
Sbjct: 524  GPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMK-GDKGELGSPGAPGLPGL-PGTPGQD 581

Query: 1393 --PAIPSPKGDPTSPAVI-PLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT 1449
              P +P PKG+P          P   P  P               PP   PV  K     
Sbjct: 582  GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG--PVGEKGIQGV 639

Query: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP--------KKAPATPAPMG 1501
            +   G P  P  KGDP      P  P  P  P +      P           P  P   G
Sbjct: 640  AGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKG 699

Query: 1502 APTLPAV---IPSSPKEVPATPSSRRDPIAPTATLLS--KKTPATLAPKEALIPPAMTVP 1556
             P +P +    P  PK  P  P     P  P    L      P    PK     P   +P
Sbjct: 700  EPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG---EPGFALP 756

Query: 1557 SPKKTPAIPTPKEAPATPSSKEASSPPAVTPST-YKGAPSPK---------ELLIPPAVT 1606
             P   P +P  K A      +    PP     T   G P PK           + PP + 
Sbjct: 757  GPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816

Query: 1607 SPSPKEAPTPPAVTPPSPEKG-PATPAPKGTPTSPPVT---PSSLKDSPTSPASVTCKMG 1662
                +  P PP +  P  + G    P  KG P  P +    P   + SP  P +     G
Sbjct: 817  GIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGA----PG 872

Query: 1663 ATVPQASKGLPAKKG----PTALKEVLVAPAPESTPIITAPTRKGPQTKK--SSATSPPI 1716
               P  S GLP K G    P    E+ +   P     +  P R G    K        P 
Sbjct: 873  PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG 932

Query: 1717 CPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAA 1776
             P P+ + GSKG      P   +      SK  KG+       G   P            
Sbjct: 933  LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP-----------K 981

Query: 1777 AFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGL--VLESPSKPLAP 1834
             ++ +   P    +S  P  P   P  P   P L P Q  L   PGL   +     P   
Sbjct: 982  GYQGLPGDPGQPGLSGQPGLPG--PPGPKGNPGL-PGQPGLIGPPGLKGTIGDMGFPGPQ 1038

Query: 1835 ADEDELLPL-IPPEPISGGVPFQSVLVNMPTPKSAGIP-VPTPSAK 1878
              E    P  +P +P S G+P Q      P   S G+P +P P  +
Sbjct: 1039 GVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE 1084


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  236 bits (601), Expect = 2e-61
 Identities = 358/1385 (25%), Positives = 436/1385 (31%), Gaps = 263/1385 (18%)

Query: 706  ENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVAS 765
            +  P  P P+    P       P  P +   P +P     PG + + G + T        
Sbjct: 80   DGIPGPPGPKGIRGPPGL----PGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPG 135

Query: 766  SPK----ECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDT-- 819
            SP     + P    G        G++  ++  P P G   +P    PP  +G  GP    
Sbjct: 136  SPGFPGLQGPPGPPGIPGMKGEPGSII-MSSLPGPKG---NPGYPGPPGIQGLPGPTGIP 191

Query: 820  -PIGNLSSP--VSPVEASFLP----ENSLSFQGSKDSPATTHSPTPPSPKGAPT------ 866
             PIG    P  + P     LP       L+FQG K          PP P G  +      
Sbjct: 192  GPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPI 251

Query: 867  -----------PSAVTPLSPKGVTLPPK----ETPTPSVVNLPFPKEGPATPAPKQAPAL 911
                       P    P  P G+  PP     E         P  +  P        P +
Sbjct: 252  DVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGI 311

Query: 912  SMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPP 971
                  P      P   G        G P PP    P P  G           P      
Sbjct: 312  PGLPGDPGYP-GEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEK 370

Query: 972  SPKGGPATPSPKGAPTPPAAT---PPSPKGGPATPSPKGAPTPPAVT---PPSPKGSPAA 1025
              +G P    P G P PP A    PP P G P     KG   PP ++   PP   G P A
Sbjct: 371  GERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGA 430

Query: 1026 -----TPFPKGASTPPA-----ATPPSPKGSPAATPL----------------------- 1052
                  P P G   PP+       PP P GSP    L                       
Sbjct: 431  PGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGIS 490

Query: 1053 -PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAA--- 1108
             P G P  P   LP P G    P  KG      AT   PKG P  P   GAP  P +   
Sbjct: 491  GPPGQPGLPG--LPGPPGSLGFPGQKGEKGQAGAT--GPKGLPGIPGAPGAPGFPGSKGE 546

Query: 1109 -----TPPSPKGGLATPPHKGAPTTPA--ATP--------PSPK---GGLATPPPKGAPT 1150
                 T P  KG        GAP  P    TP        P PK   GG+     +G P 
Sbjct: 547  PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606

Query: 1151 TPAAT---------------PPSPKG-----GLA-------TPPPKGAPTTPAATP---- 1179
             P                  PP P G     G+A        P PKG P      P    
Sbjct: 607  NPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG 666

Query: 1180 ----PSPKGGLATPSPKGAPTTPAAT------------------PPSPKGGLATPSPKGA 1217
                P   G +  P   G P  P                     PP PKG    P P GA
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726

Query: 1218 PTTPAAT----PPSPKG--------GLATPSPKGAPTTP----AATPPSPKGGPATPPP- 1260
            P TP       PP P G        G A P P G P  P    A  P   +G P  P P 
Sbjct: 727  PGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPP 786

Query: 1261 -----KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG--GPATSP-------P 1306
                  G P P     P+ + G   PP  G P   V  PP P G  GP   P        
Sbjct: 787  GRTGLDGLPGPKGDVGPNGQPGPMGPP--GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGE 844

Query: 1307 KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS-- 1364
            KG P PP    P P G  G+P   GAP P  + PP   G+P LP    +S G P T    
Sbjct: 845  KGDPGPPGLDVPGPPGERGSPGIPGAPGP--IGPP---GSPGLPGKAGAS-GFPGTKGEM 898

Query: 1365 ---SKEGPTPPAATPSHKGGPAMTPPSPKRG-PAIPSPKGDPTSPAVIPLSPKKAPATPV 1420
                  GP  P   P   G P +      +G P +P P G+  S     L     P  P 
Sbjct: 899  GMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL-----PGPPG 953

Query: 1421 TREGAATPSKGDLTPPAVTPVSLKKAPATSAPK------GGPATPSSKGDPTLPAVTPPS 1474
              +     SKG+   P +  +     P  S PK      G P  P   G P LP   PP 
Sbjct: 954  PMDPNLLGSKGEKGEPGLPGI-----PGVSGPKGYQGLPGDPGQPGLSGQPGLPG--PPG 1006

Query: 1475 PK-EPPAPKQVATSSSPKKAPAT-----PAPMG--APTLPAVIPSSPKEVPATPSSRRDP 1526
            PK  P  P Q      P           P P G   P  P+ +P  P   P  P  + D 
Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGS-PGLPGQKGDK 1065

Query: 1527 IAPTATLLSKKTPATLAPK-EALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV 1585
              P  + +    P    PK E  +P     P  K +   P     P TP +K     P  
Sbjct: 1066 GDPGISSIG--LPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF 1123

Query: 1586 TPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVT-P 1644
             P T  G P PK +  PP   +P     P P        + GP  P  KG P    +  P
Sbjct: 1124 -PGT-PGPPGPKGISGPPG--NPGLPGEPGPVGGGGHPGQPGP--PGEKGKPGQDGIPGP 1177

Query: 1645 SSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEV---LVAPAPESTPIITA-PT 1700
            +  K  P  P       G   P    GL  +KG   L  +      P P+  P     P 
Sbjct: 1178 AGQKGEPGQPG-----FGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG 1232

Query: 1701 RKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVA----PAPLLPVQKDSSKTAKGKDASH 1756
             +GP     S    P    P    G +GP         P P  P     +   KG+  + 
Sbjct: 1233 VQGPPGPPGS--PGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNP 1290

Query: 1757 SPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQF 1816
               G    P  K          +    +P    +   P  P          P+  P    
Sbjct: 1291 GQPGLPGLPGLKGDQ--GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAG 1348

Query: 1817 LPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKS-AGIPVPTP 1875
                PGL+   P  P  P    + + +I  +    G+P Q  L  +P P+   G+P PT 
Sbjct: 1349 PEGEPGLI-GPPGPPGLPGPSGQSI-IIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTG 1406

Query: 1876 SAKQP 1880
                P
Sbjct: 1407 PPGDP 1411



 Score =  224 bits (571), Expect = 7e-58
 Identities = 314/1189 (26%), Positives = 371/1189 (31%), Gaps = 203/1189 (17%)

Query: 709  PVAPSPQNTCAPLATLVLAPEIPKSVPSP------SLPPAGTPPGTKKVDGISHTSALA- 761
            P    P     P    V+ P  P   P          PP  + PG   +DG      L  
Sbjct: 376  PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435

Query: 762  -PVASSPKECPTED---------SGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTK 811
             P  + P   P+++          G+      +G      D        +      PP +
Sbjct: 436  PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 812  KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT 871
             G  G   P G+L  P    E       +   +G    P    +P  P  KG P      
Sbjct: 496  PGLPGLPGPPGSLGFPGQKGEKG--QAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTF 553

Query: 872  P--LSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKG 929
            P     KG    P     P +   P     P  P PK  P       + K  R  P   G
Sbjct: 554  PGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPG----GITFKGERGPPGNPG 609

Query: 930  IPASPSPKGAPTPPAATPPSP------------KGGPATPSPKWAPTPPAATP------- 970
            +P  P   G   PP   PP P             G P  P PK  P      P       
Sbjct: 610  LPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 971  ----------------PSPKGGPATPSPKGAPTPPAAT---PPSPKGGPATPSPKGAP-T 1010
                            P   G P  P  KG P  P      PP PKG P  P P GAP T
Sbjct: 670  NPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGT 729

Query: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA-----------ATPLPKGAP-T 1058
            P  +    P G P   P PKG        PP P G P              P P G P  
Sbjct: 730  PGRIGLEGPPG-PPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGR 788

Query: 1059 TPAATLPSPKG--------GPATP------SLKGAPTPPAATPPSPKGGP---ATPSPKG 1101
            T    LP PKG        GP  P       ++G P PP    P P G P     P  KG
Sbjct: 789  TGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI--PGPIGQPGLHGIPGEKG 846

Query: 1102 APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT------ 1155
             P PP    P P G   +P   GAP      P  P G    P   GA   P         
Sbjct: 847  DPGPPGLDVPGPPGERGSPGIPGAP-----GPIGPPGSPGLPGKAGASGFPGTKGEMGMM 901

Query: 1156 -PPSPKGGLATPPPKGAPTTPAATP-------PSPKGGLATPSPKGAPTTPAATPPSPKG 1207
             PP P G L  P   G P              P P G   +    G P  P    P+  G
Sbjct: 902  GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLG 961

Query: 1208 GLATPSPKGAPTTPAATPPSPKGGL----ATPSPKGAPTTPAATPPSPKGGPATPPPKGA 1263
                    G P  P  + P    GL      P   G P  P   PP PKG P  P     
Sbjct: 962  SKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG--PPGPKGNPGLP----- 1014

Query: 1264 PTPPAATPPSLKGGLATPPHKGAPNP-AVVTPPSPKGGPATSPPKGAPTPPAATPP---S 1319
              P    PP LKG   T    G P P  V  PP P G P      G P           S
Sbjct: 1015 GQPGLIGPPGLKG---TIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGIS 1071

Query: 1320 PKGSPGTPPPKGAPTPPAVTPPSP--------KGTPTLPATTPSSKGGPTTPSSKEGPTP 1371
              G PG P PKG P  P   P +P         G P LP  TP +KG P  P     P P
Sbjct: 1072 SIGLPGLPGPKGEPGLPGY-PGNPGIKGSVGDPGLPGLPG-TPGAKGQPGLPGFPGTPGP 1129

Query: 1372 PAATPSHKGGPAMTP-----PSPKRG---PAIPSPKGDPTSPAVIPLSPKKAPATPVTRE 1423
            P   P    GP   P     P P  G   P  P P G+   P          P     + 
Sbjct: 1130 PG--PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKP-----GQDGIPGPAGQKG 1182

Query: 1424 GAATPSKGDLTPPAVTPVSLKKAP-ATSAPKGGPATPSSKGDP---TLPAVT-PPSPKEP 1478
                P  G+  PP +  +S +K         G P  P  KG+P     P V  PP P   
Sbjct: 1183 EPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS 1242

Query: 1479 PAPKQVATSSSPKKAPATPAPMGAPTLPAVI-PSSPKEVPATPSSRRDPIAPTATLLSKK 1537
            P P        PK  P    P G P    +  P  P  +P     + +   P    L   
Sbjct: 1243 PGP----ALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGL--- 1295

Query: 1538 TPATLAPKEALIPPAMT-------VPSPKKTPAIPTPKEAPAT--PSSKEASSPPAVTPS 1588
             P     K    PP +        +   K  P +P     P    PS    S+ P   P 
Sbjct: 1296 -PGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPG 1354

Query: 1589 TYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGT--PTSPPVTPSS 1646
               G P P  L  P   +     +A  P     P  +  P    P+G   PT PP  P  
Sbjct: 1355 LI-GPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGR 1413

Query: 1647 LKDSPTSPASVTCKMGATVP--QASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGP 1704
                P    +   K    +P    ++GL    GP  L+       P   P  ++      
Sbjct: 1414 -NGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQ------GPPGPPGTSSVAHGFL 1466

Query: 1705 QTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKD 1753
             T+ S  T  P CP        +G L       LL VQ   +K A G+D
Sbjct: 1467 ITRHSQTTDAPQCP--------QGTLQVYEGFSLLYVQ--GNKRAHGQD 1505



 Score =  212 bits (539), Expect = 3e-54
 Identities = 290/1066 (27%), Positives = 339/1066 (31%), Gaps = 156/1066 (14%)

Query: 918  PKKARATPAPKGIPASPSPKGAPTPPAATP-PSPKGGPATPSPKWAPTP---PAATPPSP 973
            P   R      GIP  P PKG   PP     P   G P  P    AP P   P       
Sbjct: 70   PPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKG 129

Query: 974  K----GGPATPSPKGAPTPPAATPPSPKGGPAT------PSPKGAPTPPAVTPPSPKGSP 1023
            +    G P  P  +G P PP    P  KG P +      P PKG P  P   PP  +G P
Sbjct: 130  ERGFPGSPGFPGLQGPPGPPGI--PGMKGEPGSIIMSSLPGPKGNPGYPG--PPGIQGLP 185

Query: 1024 AAT--PFPKGASTPPAAT-PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP 1080
              T  P P G   PP    PP P G P     PKG           PKG      L+G P
Sbjct: 186  GPTGIPGPIGPPGPPGLMGPPGPPGLPG----PKG---NMGLNFQGPKGEKGEQGLQGPP 238

Query: 1081 TPPAATPPS--------PKGGPATPSPKGAPMPPAAT-PPSPKGGLATPPHKGAPTTPAA 1131
             PP               KG    P  +G P PP    PP P GG      KG    P  
Sbjct: 239  GPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGG--EKGEKGEQGEPGK 296

Query: 1132 T-PPSPKGGLATPPPKGAPTTPA-ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1189
               P   G    P   G P  P     P   G        G P  P    P P  G+ T 
Sbjct: 297  RGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGI-TI 355

Query: 1190 SPKGAPTTPAATPPSPKGGLATP---SPKGAPTTPAAT---PPSPKGGLATPSPKGAPTT 1243
              KG    P    P  KG    P    P G P  P A    PP P G       KG    
Sbjct: 356  GEKGNIGLPGL--PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGP 413

Query: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG---- 1299
            P  + P P G    P   G P PP    P +      PP      P    PP   G    
Sbjct: 414  PGISIPGPPGLDGQPGAPGLPGPPGPAGPHI------PPSDEICEPGPPGPPGSPGDKGL 467

Query: 1300 ------------------GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341
                              G   S P G P  P    P P GS G P  KG       T  
Sbjct: 468  QGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGL--PGPPGSLGFPGQKGEKGQAGAT-- 523

Query: 1342 SPKGTPTLPATT-----PSSKGGP----TTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392
             PKG P +P        P SKG P    T P  K G      +P   G P + P +P + 
Sbjct: 524  GPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMK-GDKGELGSPGAPGLPGL-PGTPGQD 581

Query: 1393 --PAIPSPKGDPTSPAVI-PLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT 1449
              P +P PKG+P          P   P  P               PP   PV  K     
Sbjct: 582  GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG--PVGEKGIQGV 639

Query: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP--------KKAPATPAPMG 1501
            +   G P  P  KGDP      P  P  P  P +      P           P  P   G
Sbjct: 640  AGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKG 699

Query: 1502 APTLPAV---IPSSPKEVPATPSSRRDPIAPTATLLS--KKTPATLAPKEALIPPAMTVP 1556
             P +P +    P  PK  P  P     P  P    L      P    PK     P   +P
Sbjct: 700  EPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG---EPGFALP 756

Query: 1557 SPKKTPAIPTPKEAPATPSSKEASSPPAVTPST-YKGAPSPK---------ELLIPPAVT 1606
             P   P +P  K A      +    PP     T   G P PK           + PP + 
Sbjct: 757  GPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816

Query: 1607 SPSPKEAPTPPAVTPPSPEKG-PATPAPKGTPTSPPVT---PSSLKDSPTSPASVTCKMG 1662
                +  P PP +  P  + G    P  KG P  P +    P   + SP  P +     G
Sbjct: 817  GIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGA----PG 872

Query: 1663 ATVPQASKGLPAKKG----PTALKEVLVAPAPESTPIITAPTRKGPQTKK--SSATSPPI 1716
               P  S GLP K G    P    E+ +   P     +  P R G    K        P 
Sbjct: 873  PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG 932

Query: 1717 CPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAA 1776
             P P+ + GSKG      P   +      SK  KG+       G   P            
Sbjct: 933  LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP-----------K 981

Query: 1777 AFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGL--VLESPSKPLAP 1834
             ++ +   P    +S  P  P   P  P   P L P Q  L   PGL   +     P   
Sbjct: 982  GYQGLPGDPGQPGLSGQPGLPG--PPGPKGNPGL-PGQPGLIGPPGLKGTIGDMGFPGPQ 1038

Query: 1835 ADEDELLPL-IPPEPISGGVPFQSVLVNMPTPKSAGIP-VPTPSAK 1878
              E    P  +P +P S G+P Q      P   S G+P +P P  +
Sbjct: 1039 GVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE 1084


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  228 bits (580), Expect = 6e-59
 Identities = 314/1135 (27%), Positives = 393/1135 (34%), Gaps = 165/1135 (14%)

Query: 596  GEPLPIGKPASSMTSPLGVNSSASVIKTDSYAG--PDSAGPLLKSSLITPTVAAFPLESA 653
            G P P G P       LG N +A +      AG   + AG      +  P     P    
Sbjct: 159  GNPGPPGPPGPPGPPGLGGNFAAQM------AGGFDEKAGGAQLGVMQGPMGPMGPRGPP 212

Query: 654  DPAGVAPTTAKGTSTYTTTASPFLEGTVS-LAPKNHPVKEGTLTTLPLVPTASENCPVAP 712
             PAG AP              P + G +    P   P K G          A E  P  P
Sbjct: 213  GPAG-APGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP--P 269

Query: 713  SPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSAL--APVASSPKEC 770
             PQ       T  L P +      P L  A    G   V G S +     +P    P+  
Sbjct: 270  GPQGARGFPGTPGL-PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGL 328

Query: 771  PTED--SGASATASSKGT--LTYLADSPSPLGVSVSPQTKRPPTKKGSAGP--------- 817
            P E   +G +  A ++G       A  P P+G +  P     P  KG AGP         
Sbjct: 329  PGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGA 388

Query: 818  DTPIGNLSSPVSP--VEASFLP--ENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT-P 872
              P G   +P SP    AS  P  +     +GS  +P    +P  P P+G P P   T P
Sbjct: 389  QGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP 448

Query: 873  LSPKGVTLPPKETPTPSVVNL-----PFPKEGPATPAPKQAPALSMTSSSPKKARATPAP 927
            L PKG      +T  P +        P  + GPA P     PA        + AR  P  
Sbjct: 449  LGPKG------QTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA---GEEGKRGARGEPGG 499

Query: 928  KGIPASPSPKGAPT----PPAATPPSPKGGPATPSPKWAPTPPAAT-PPSPKGGPATPSP 982
             G    P  +GAP     P       PKG P    P     P  A   P   G P  P  
Sbjct: 500  VGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGA 559

Query: 983  KGAPTPPAATPPSPKGGPA-TPSPKGAPTPPAVTPPSPKGSPAATPFP--KGASTPPA-A 1038
            +G    P    P  K GP+  P   G P PP   P   +G P    FP  KGA+  P  A
Sbjct: 560  RGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPG--PQGARGQPGVMGFPGPKGANGEPGKA 617

Query: 1039 TPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT----PPSPKGGP 1094
                  G+P    LP     T AA  P P G       +GAP P        PP P G  
Sbjct: 618  GEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEG 677

Query: 1095 ATPSPKGAPMPPAATP-PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1153
              P  +G P    A     P+G    P  +G+P           G      P+G P TP 
Sbjct: 678  GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSP-----------GAQGLQGPRGLPGTPG 726

Query: 1154 ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1213
               P    G A PP        A  PP  +G    P  +GA     A P   +G +    
Sbjct: 727  TDGPKGASGPAGPPG-------AQGPPGLQG---MPGERGA--AGIAGPKGDRGDVGEKG 774

Query: 1214 PKGAP-------TTPAATPPSP------KGGLATPSPKGAPTTPAATPPSPKGGPATPPP 1260
            P+GAP        T    PP P      KG +  P P G+     A  P  +G    P P
Sbjct: 775  PEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA--PGERGETGPPGP 832

Query: 1261 KGAPTPPAAT-PPSLKGGLATPPHKG---APNPAVVT-PPSPKGGPATSPPKGA---PTP 1312
             G   PP A   P  KG       KG   AP P   +  P P+G    + PKGA     P
Sbjct: 833  AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 892

Query: 1313 PAATP-PSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP 1371
            P AT  P   G  G P   G P PP   PP P G          S  GP   + + G   
Sbjct: 893  PGATGFPGAAGRVGPPGSNGNPGPPG--PPGPSGKDGPKGARGDS--GPPGRAGEPGLQG 948

Query: 1372 PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA---------PATPVTR 1422
            PA  P  KG P    PS   GP  P P+G      ++ L  ++          P+    +
Sbjct: 949  PAGPPGEKGEPGDDGPSGAEGP--PGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGK 1006

Query: 1423 EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPK 1482
            +GA   S GD  PP   PV     P  + P G P    S G     A  PP        K
Sbjct: 1007 QGAPGAS-GDRGPPG--PVG---PPGLTGPAGEPGREGSPG-----ADGPPGRDGAAGVK 1055

Query: 1483 QVATSSSPKKAPATPAPMGAPTLPAVIPSSP--KEVPATPSSRRDPIAPTATLLSKKTPA 1540
                 +    AP  P P G+P      P+ P  K+     +  + P+ P+    ++    
Sbjct: 1056 GDRGETGAVGAPGAPGPPGSPG-----PAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQG 1110

Query: 1541 TLAPK----EALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSP 1596
               P+    EA  P    +   +    +      P  PS  + +S PA  PS  +G P P
Sbjct: 1111 PQGPRGDKGEAGEPGERGLKGHRGFTGLQG-LPGPPGPSGDQGASGPA-GPSGPRGPPGP 1168

Query: 1597 KELLIPPAVTSPSPKEAPT--PPAVTPPSP-----EKGPATPAPKGTPTSPPVTP 1644
                       PS K+     P  + PP P     E GPA P     P  PP  P
Sbjct: 1169 ---------VGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP 1214



 Score =  224 bits (571), Expect = 7e-58
 Identities = 307/1193 (25%), Positives = 379/1193 (31%), Gaps = 170/1193 (14%)

Query: 726  LAPEIPKSVPSPSLPP----AGTPPGTKKVDGISHT--SALAPVASSPKECPTEDSGASA 779
            L+PEIP     P  P     A   PG K   G        + P      + P  + G   
Sbjct: 76   LSPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRG 135

Query: 780  TASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPEN 839
                KG       +P P G    P T   P   G  GP  P G   +  + +   F  + 
Sbjct: 136  DRGDKGE----KGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKA 191

Query: 840  SLSFQGSKDSPATTHSPT-PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKE 898
              +  G    P     P  PP P GAP         P+G    P E   P V   P    
Sbjct: 192  GGAQLGVMQGPMGPMGPRGPPGPAGAP--------GPQGFQGNPGEPGEPGVSG-PMGPR 242

Query: 899  GPATPAPKQAPALSMTSSSPKKA--RATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT 956
            GP  P P   P     +  P KA  R  P P+G    P   G P          +G P  
Sbjct: 243  GP--PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGH-----RGYPGL 295

Query: 957  PSPKWAPTPPAAT----PPSPKGGPATPSPKGAPTPPAATPPS----PKGGPATPSPKGA 1008
               K     P        P   G P    P+G P     T P+     +G    P P G 
Sbjct: 296  DGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGP 355

Query: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPK 1068
            P P  V P    G P A P  KG + P  A    P+G+      P+G P TP +  P P 
Sbjct: 356  PGP--VGPAGGPGFPGA-PGAKGEAGPTGAR--GPEGAQG----PRGEPGTPGS--PGPA 404

Query: 1069 GGPATPSLKGAP-TPPAATPPSPKGGPATPSPKGAPMPPAATPP-SPKGGLATPPHKGAP 1126
            G    P   G P    +A  P   G P  P P+G P P  AT P  PKG    P   G  
Sbjct: 405  GASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFK 464

Query: 1127 TTPAAT-PPSPKGGLATPPP------KGAPTTPAATPP-SPKGGLATPPPKGAPT----- 1173
                    P P G    P P      +GA   P    P  P G    P  +G P      
Sbjct: 465  GEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLA 524

Query: 1174 ----TPAATPPS----PKGGLATPSPKGAPTTPAATPPSPKGGLATPS----PKGAPTTP 1221
                 P    PS    PKG    P   G P  P A   + + G A P     P GAP   
Sbjct: 525  GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED 584

Query: 1222 AAT-PPSPKGG------LATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP----AAT 1270
                PP P+G       +  P PKGA   P       KG P  P  +G P       AA 
Sbjct: 585  GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKA--GEKGLPGAPGLRGLPGKDGETGAAG 642

Query: 1271 PPSLKGGLATPPHKGAPNPA----VVTPPSPKGGPATSPPKGAPTPPAATP-PSPKGSPG 1325
            PP   G       +GAP P+    +  PP P G       +G P    A     P+G  G
Sbjct: 643  PPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERG 702

Query: 1326 TPPPKGAPTPPAVTPPSPKGTPTLPATT-PSSKGGPTTPSSKEGPTPPAATPSHKGGPAM 1384
             P  +G+P    +    P+G P  P T  P    GP  P   +GP      P  +G   +
Sbjct: 703  FPGERGSPGAQGLQ--GPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 760

Query: 1385 TPPSPKRGPA-IPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSL 1443
              P   RG      P+G P       L+    P  P    G     KG++ PP       
Sbjct: 761  AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANG----EKGEVGPPG------ 810

Query: 1444 KKAPATSAPKGGPATPSSKGD--PTLPA--VTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499
               PA SA  G    P  +G+  P  PA    PP     P  K     +  K     P P
Sbjct: 811  ---PAGSA--GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGP 865

Query: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP--PAMTVPS 1557
             G    P   P  P  V     +R     P AT           P     P  P    PS
Sbjct: 866  QGPSGAPG--PQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPS 923

Query: 1558 PKKTPAIPTPKEAP----ATPSSKEASSPPAVT-------PSTYKGAPSPKELLIPPAVT 1606
             K  P        P      P  +  + PP          PS  +G P P+ L     + 
Sbjct: 924  GKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV 983

Query: 1607 S-PSPKEAPTPPAVTPPSPEKG----PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKM 1661
              P  +     P +  PS E G    P     +G P   PV P  L   P          
Sbjct: 984  GLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPG--PVGPPGLT-GPAGEPGREGSP 1040

Query: 1662 GATVP---QASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICP 1718
            GA  P     + G+   +G T       AP P  +P    PT K     ++ A  P    
Sbjct: 1041 GADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPS 1100

Query: 1719 DPSAKNGSKGPLSTVA-------------------------PAPLLPVQKDSSKTAKGKD 1753
             P+   G +GP                              P P  P     +    G  
Sbjct: 1101 GPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPS 1160

Query: 1754 ASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSP 1806
                P GP+ P     +  +         P P   S    P+ P   P  P P
Sbjct: 1161 GPRGPPGPVGPSGKDGANGIPGPIGP---PGPRGRSGETGPAGPPGNPGPPGP 1210



 Score =  200 bits (508), Expect = 1e-50
 Identities = 277/1056 (26%), Positives = 330/1056 (31%), Gaps = 172/1056 (16%)

Query: 857  TPPSPKGAPTPSAVTPLSPKGVTLPPK--ETPTPSVVNLPFPK--EGPATPAPKQAPALS 912
            +P  P G   P   T L+       PK  +     + ++  PK   GP  PA +Q P   
Sbjct: 77   SPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGP--- 133

Query: 913  MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPA-------------TPSP 959
                  K  +  P P+G    P   G P PP   PP P G P                  
Sbjct: 134  RGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPG--PPGPPGPPGLGGNFAAQMAGGFDEKA 191

Query: 960  KWAPTPPAATPPSPKGGPATPSPKGAPTPPA-ATPPSPKGGPATPSPKGAPTPPAVTPPS 1018
              A       P  P G    P P GAP P      P   G P    P G   PP   PP 
Sbjct: 192  GGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPG--PPG 249

Query: 1019 PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG 1078
              G       P  A       PP P+G+       +G P TP   LP  KG    P L G
Sbjct: 250  KPGDDGEAGKPGKAG---ERGPPGPQGA-------RGFPGTPG--LPGVKGHRGYPGLDG 297

Query: 1079 APTPPAATPPSPKGGPATPSPKGAPMP--PAATP-----PSPKGGLATPPHKGAPTTPAA 1131
            A     A  P  KG   +P   G+P P  P   P       P G      + G P    A
Sbjct: 298  AKGEAGA--PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQP--GPA 353

Query: 1132 TPPSPKGGLATPPPKGAPTTPA-ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS 1190
             PP P G    P   GAP     A P   +G      P+G P TP +  P P G    P 
Sbjct: 354  GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGS--PGPAGASGNPG 411

Query: 1191 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT-PPSPKGGLATPSPKGAPTTPAAT-- 1247
              G         P  KG    P   GAP  P    PP P+G      PKG    P     
Sbjct: 412  TDGI--------PGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGF 463

Query: 1248 --PPSPKGGPATPPPKGAPTPP-------AATPPSLKGGLATPPHKGAPN----PAVVTP 1294
                 PKG P    P+GAP P        A   P   G +  P  +GAP     P     
Sbjct: 464  KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGL 523

Query: 1295 PSPKGGPATSPPKGAPTPPAAT-PPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353
              PKG P    P G   P  A   P   G PG P  +G    P    P  K     P+  
Sbjct: 524  AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGK---VGPSGA 580

Query: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK 1413
            P   G P  P    GP      P   G P   P      P     KG P +P +  L  K
Sbjct: 581  PGEDGRPGPP----GPQGARGQPGVMGFPG--PKGANGEPGKAGEKGLPGAPGLRGLPGK 634

Query: 1414 KAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPP 1473
                      G A P+       A  P   +  P    P G    P  +G          
Sbjct: 635  DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQG---------- 684

Query: 1474 SPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATL 1533
             P E  AP  V     P+     P   G+P    +    P+ +P TP           T 
Sbjct: 685  VPGEAGAPGLV----GPRGERGFPGERGSPGAQGL--QGPRGLPGTP----------GTD 728

Query: 1534 LSKKTPATLAPKEALIPPAMT-VPSPKKTPAIPTPK------------EAPATPSSKEAS 1580
              K       P  A  PP +  +P  +    I  PK             AP     +  +
Sbjct: 729  GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT 788

Query: 1581 SPPAVTPSTYKGAPSPKELLIPPA-VTSPSPKEAPTPPAVT-PPSPEKGPATPAPKGTPT 1638
             P  + P    GA   K  + PP    S   + AP     T PP P      P   G P 
Sbjct: 789  GP--IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPG 846

Query: 1639 SPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT- 1697
            +               A      GA  PQ   G P  +GPT +     A   +  P  T 
Sbjct: 847  A---------KGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATG 897

Query: 1698 ---APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDA 1754
               A  R GP     +   PP  P PS K+G KG      P               G+  
Sbjct: 898  FPGAAGRVGPPGSNGN-PGPPGPPGPSGKDGPKGARGDSGP--------------PGRAG 942

Query: 1755 SHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQ 1814
                +GP  PP  K               +P     S A  PP    LA        P Q
Sbjct: 943  EPGLQGPAGPPGEKG--------------EPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQ 988

Query: 1815 QFLPSSPGLVLES--PSKPLAPADEDELLPLIPPEP 1848
            +     PGL   S  P K  AP    +  P  P  P
Sbjct: 989  RGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGP 1024



 Score =  164 bits (414), Expect = 1e-39
 Identities = 238/904 (26%), Positives = 267/904 (29%), Gaps = 284/904 (31%)

Query: 731  PKSVPSPSLPPAGTP-----PGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKG 785
            P   P P + PAG P     PG K   G   T A  P             GA       G
Sbjct: 352  PAGPPGP-VGPAGGPGFPGAPGAKGEAG--PTGARGP------------EGAQGPRGEPG 396

Query: 786  TLTYLADSPSPLGVSVSPQTKRPPTKKGSAG------------PDTPIG--NLSSPVSPV 831
            T      SP P G S +P T   P  KGSAG            P  P G    + P+ P 
Sbjct: 397  T----PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPK 452

Query: 832  EASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA-------------VTPLSPKGV 878
              +  P       G K        P P  P+GAP P+              V P+ P G 
Sbjct: 453  GQTGEP----GIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGE 508

Query: 879  TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKG 938
               P     P    L  PK  P    P          + PK A   P   G P  P  +G
Sbjct: 509  RGAPGNRGFPGQDGLAGPKGAPGERGPSGL-------AGPKGANGDPGRPGEPGLPGARG 561

Query: 939  APTPPAATPPSPKGGPA-TPSPKWAPTPPAATP----------PSPKGG---PATPSPKG 984
                P    P  K GP+  P     P PP              P PKG    P     KG
Sbjct: 562  LTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKG 621

Query: 985  APTPP-------------AATPPSPKGGPATPSPKGAPTPPAVT-------PPSPKGSPA 1024
             P  P             AA PP P G       +GAP P           PP   G P 
Sbjct: 622  LPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPG 681

Query: 1025 ATPFPKGASTPPAATP------PSPKGSPAATPL--PKGAPTTPAATLPSPKGGPATPSL 1076
                P  A  P    P      P  +GSP A  L  P+G P TP    P    GPA P  
Sbjct: 682  DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP- 740

Query: 1077 KGAPTPPA-------------ATPPSPKGGPATPSPKGAP-------MPPAATPPSPKG- 1115
             GA  PP              A P   +G      P+GAP       +     PP P G 
Sbjct: 741  -GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 799

Query: 1116 ----GLATPPH-------KGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT----PPSPK 1160
                G   PP        +GAP     T P    G A PP  GA   P A         K
Sbjct: 800  NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP--GADGQPGAKGEQGEAGQK 857

Query: 1161 GGLATPPPKGAPTTPAATPPS----PKGGLATPSPKGAPTTPAAT-------------PP 1203
            G    P P+G    P    P+    PKG      P GA   P A              PP
Sbjct: 858  GDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPP 917

Query: 1204 SPKGGLATPSPKGA-----------------PTTP--------------AATPPSPKG-- 1230
             P G      PKGA                 P  P              A  PP P+G  
Sbjct: 918  GPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLA 977

Query: 1231 ------GL----------ATPSPKGAPTTPAAT-------PPSPKGGPATPPPKGAP--- 1264
                  GL            P P G P    A        PP P G P    P G P   
Sbjct: 978  GQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGRE 1037

Query: 1265 -TPPAATPPSLKGGLATPPHKGAPNPAVVTP--PSPKGGPATSPPKG------------- 1308
             +P A  PP   G       +G    AV  P  P P G P  + P G             
Sbjct: 1038 GSPGADGPPGRDGAAGVKGDRGETG-AVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1096

Query: 1309 -APTPPAAT--------------------------------------PPSP---KGSPGT 1326
              P+ PA                                        PP P   +G+ G 
Sbjct: 1097 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1156

Query: 1327 PPPKGAPTPPAVTPPSPK-GTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385
              P G   PP    PS K G   +P   P    GP   S + GP  P   P   G P   
Sbjct: 1157 AGPSGPRGPPGPVGPSGKDGANGIPG--PIGPPGPRGRSGETGPAGPPGNPGPPGPPG-- 1212

Query: 1386 PPSP 1389
            PP P
Sbjct: 1213 PPGP 1216


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  228 bits (580), Expect = 6e-59
 Identities = 314/1135 (27%), Positives = 393/1135 (34%), Gaps = 165/1135 (14%)

Query: 596  GEPLPIGKPASSMTSPLGVNSSASVIKTDSYAG--PDSAGPLLKSSLITPTVAAFPLESA 653
            G P P G P       LG N +A +      AG   + AG      +  P     P    
Sbjct: 90   GNPGPPGPPGPPGPPGLGGNFAAQM------AGGFDEKAGGAQLGVMQGPMGPMGPRGPP 143

Query: 654  DPAGVAPTTAKGTSTYTTTASPFLEGTVS-LAPKNHPVKEGTLTTLPLVPTASENCPVAP 712
             PAG AP              P + G +    P   P K G          A E  P  P
Sbjct: 144  GPAG-APGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP--P 200

Query: 713  SPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSAL--APVASSPKEC 770
             PQ       T  L P +      P L  A    G   V G S +     +P    P+  
Sbjct: 201  GPQGARGFPGTPGL-PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGL 259

Query: 771  PTED--SGASATASSKGT--LTYLADSPSPLGVSVSPQTKRPPTKKGSAGP--------- 817
            P E   +G +  A ++G       A  P P+G +  P     P  KG AGP         
Sbjct: 260  PGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGA 319

Query: 818  DTPIGNLSSPVSP--VEASFLP--ENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT-P 872
              P G   +P SP    AS  P  +     +GS  +P    +P  P P+G P P   T P
Sbjct: 320  QGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP 379

Query: 873  LSPKGVTLPPKETPTPSVVNL-----PFPKEGPATPAPKQAPALSMTSSSPKKARATPAP 927
            L PKG      +T  P +        P  + GPA P     PA        + AR  P  
Sbjct: 380  LGPKG------QTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA---GEEGKRGARGEPGG 430

Query: 928  KGIPASPSPKGAPT----PPAATPPSPKGGPATPSPKWAPTPPAAT-PPSPKGGPATPSP 982
             G    P  +GAP     P       PKG P    P     P  A   P   G P  P  
Sbjct: 431  VGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGA 490

Query: 983  KGAPTPPAATPPSPKGGPA-TPSPKGAPTPPAVTPPSPKGSPAATPFP--KGASTPPA-A 1038
            +G    P    P  K GP+  P   G P PP   P   +G P    FP  KGA+  P  A
Sbjct: 491  RGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPG--PQGARGQPGVMGFPGPKGANGEPGKA 548

Query: 1039 TPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT----PPSPKGGP 1094
                  G+P    LP     T AA  P P G       +GAP P        PP P G  
Sbjct: 549  GEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEG 608

Query: 1095 ATPSPKGAPMPPAATP-PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1153
              P  +G P    A     P+G    P  +G+P           G      P+G P TP 
Sbjct: 609  GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSP-----------GAQGLQGPRGLPGTPG 657

Query: 1154 ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1213
               P    G A PP        A  PP  +G    P  +GA     A P   +G +    
Sbjct: 658  TDGPKGASGPAGPPG-------AQGPPGLQG---MPGERGA--AGIAGPKGDRGDVGEKG 705

Query: 1214 PKGAP-------TTPAATPPSP------KGGLATPSPKGAPTTPAATPPSPKGGPATPPP 1260
            P+GAP        T    PP P      KG +  P P G+     A  P  +G    P P
Sbjct: 706  PEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA--PGERGETGPPGP 763

Query: 1261 KGAPTPPAAT-PPSLKGGLATPPHKG---APNPAVVT-PPSPKGGPATSPPKGA---PTP 1312
             G   PP A   P  KG       KG   AP P   +  P P+G    + PKGA     P
Sbjct: 764  AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 823

Query: 1313 PAATP-PSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP 1371
            P AT  P   G  G P   G P PP   PP P G          S  GP   + + G   
Sbjct: 824  PGATGFPGAAGRVGPPGSNGNPGPPG--PPGPSGKDGPKGARGDS--GPPGRAGEPGLQG 879

Query: 1372 PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA---------PATPVTR 1422
            PA  P  KG P    PS   GP  P P+G      ++ L  ++          P+    +
Sbjct: 880  PAGPPGEKGEPGDDGPSGAEGP--PGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGK 937

Query: 1423 EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPK 1482
            +GA   S GD  PP   PV     P  + P G P    S G     A  PP        K
Sbjct: 938  QGAPGAS-GDRGPPG--PVG---PPGLTGPAGEPGREGSPG-----ADGPPGRDGAAGVK 986

Query: 1483 QVATSSSPKKAPATPAPMGAPTLPAVIPSSP--KEVPATPSSRRDPIAPTATLLSKKTPA 1540
                 +    AP  P P G+P      P+ P  K+     +  + P+ P+    ++    
Sbjct: 987  GDRGETGAVGAPGAPGPPGSPG-----PAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQG 1041

Query: 1541 TLAPK----EALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSP 1596
               P+    EA  P    +   +    +      P  PS  + +S PA  PS  +G P P
Sbjct: 1042 PQGPRGDKGEAGEPGERGLKGHRGFTGLQG-LPGPPGPSGDQGASGPA-GPSGPRGPPGP 1099

Query: 1597 KELLIPPAVTSPSPKEAPT--PPAVTPPSP-----EKGPATPAPKGTPTSPPVTP 1644
                       PS K+     P  + PP P     E GPA P     P  PP  P
Sbjct: 1100 ---------VGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP 1145



 Score =  219 bits (559), Expect = 2e-56
 Identities = 294/1142 (25%), Positives = 363/1142 (31%), Gaps = 164/1142 (14%)

Query: 771  PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSP 830
            P  + G       KG       +P P G    P T   P   G  GP  P G   +  + 
Sbjct: 58   PAGEQGPRGDRGDKGE----KGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQ 113

Query: 831  VEASFLPENSLSFQGSKDSPATTHSPT-PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPS 889
            +   F  +   +  G    P     P  PP P GAP         P+G    P E   P 
Sbjct: 114  MAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAP--------GPQGFQGNPGEPGEPG 165

Query: 890  VVNLPFPKEGPATPAPKQAPALSMTSSSPKKA--RATPAPKGIPASPSPKGAPTPPAATP 947
            V   P    GP  P P   P     +  P KA  R  P P+G    P   G P       
Sbjct: 166  VSG-PMGPRGP--PGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGH-- 220

Query: 948  PSPKGGPATPSPKWAPTPPAAT----PPSPKGGPATPSPKGAPTPPAATPPS----PKGG 999
               +G P     K     P        P   G P    P+G P     T P+     +G 
Sbjct: 221  ---RGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN 277

Query: 1000 PATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTT 1059
               P P G P P  V P    G P A P  KG + P  A    P+G+      P+G P T
Sbjct: 278  DGQPGPAGPPGP--VGPAGGPGFPGA-PGAKGEAGPTGAR--GPEGAQG----PRGEPGT 328

Query: 1060 PAATLPSPKGGPATPSLKGAP-TPPAATPPSPKGGPATPSPKGAPMPPAATPP-SPKGGL 1117
            P +  P P G    P   G P    +A  P   G P  P P+G P P  AT P  PKG  
Sbjct: 329  PGS--PGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT 386

Query: 1118 ATPPHKGAPTTPAAT-PPSPKGGLATPPP------KGAPTTPAATPP-SPKGGLATPPPK 1169
              P   G          P P G    P P      +GA   P    P  P G    P  +
Sbjct: 387  GEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNR 446

Query: 1170 GAPT---------TPAATPPS----PKGGLATPSPKGAPTTPAATPPSPKGGLATPS--- 1213
            G P           P    PS    PKG    P   G P  P A   + + G A P    
Sbjct: 447  GFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKV 506

Query: 1214 -PKGAPTTPAAT-PPSPKGG------LATPSPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265
             P GAP       PP P+G       +  P PKGA   P       KG P  P  +G P 
Sbjct: 507  GPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKA--GEKGLPGAPGLRGLPG 564

Query: 1266 PP----AATPPSLKGGLATPPHKGAPNPA----VVTPPSPKGGPATSPPKGAPTPPAATP 1317
                  AA PP   G       +GAP P+    +  PP P G       +G P    A  
Sbjct: 565  KDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPG 624

Query: 1318 -PSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT-PSSKGGPTTPSSKEGPTPPAAT 1375
               P+G  G P  +G+P    +    P+G P  P T  P    GP  P   +GP      
Sbjct: 625  LVGPRGERGFPGERGSPGAQGLQ--GPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 682

Query: 1376 PSHKGGPAMTPPSPKRGPA-IPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT 1434
            P  +G   +  P   RG      P+G P       L+    P  P    G     KG++ 
Sbjct: 683  PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANG----EKGEVG 738

Query: 1435 PPAVTPVSLKKAPATSAPKGGPATPSSKGD--PTLPA--VTPPSPKEPPAPKQVATSSSP 1490
            PP          PA SA  G    P  +G+  P  PA    PP     P  K     +  
Sbjct: 739  PPG---------PAGSA--GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQ 787

Query: 1491 KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP 1550
            K     P P G    P   P  P  V     +R     P AT           P     P
Sbjct: 788  KGDAGAPGPQGPSGAPG--PQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNP 845

Query: 1551 --PAMTVPSPKKTPAIPTPKEAP----ATPSSKEASSPPAVT-------PSTYKGAPSPK 1597
              P    PS K  P        P      P  +  + PP          PS  +G P P+
Sbjct: 846  GPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQ 905

Query: 1598 ELLIPPAVTS-PSPKEAPTPPAVTPPSPEKG----PATPAPKGTPTSPPVTPSSLKDSPT 1652
             L     +   P  +     P +  PS E G    P     +G P   PV P  L   P 
Sbjct: 906  GLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPG--PVGPPGLT-GPA 962

Query: 1653 SPASVTCKMGATVP---QASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKS 1709
                     GA  P     + G+   +G T       AP P  +P    PT K     ++
Sbjct: 963  GEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEA 1022

Query: 1710 SATSPPICPDPSAKNGSKGPLSTVA-------------------------PAPLLPVQKD 1744
             A  P     P+   G +GP                              P P  P    
Sbjct: 1023 GAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQ 1082

Query: 1745 SSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAP 1804
             +    G      P GP+ P     +  +         P P   S    P+ P   P  P
Sbjct: 1083 GASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGP---PGPRGRSGETGPAGPPGNPGPP 1139

Query: 1805 SP 1806
             P
Sbjct: 1140 GP 1141



 Score =  199 bits (506), Expect = 2e-50
 Identities = 267/1010 (26%), Positives = 314/1010 (31%), Gaps = 168/1010 (16%)

Query: 899  GPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPA--- 955
            GP  PA +Q P         K  +  P P+G    P   G P PP   PP P G P    
Sbjct: 54   GPQGPAGEQGP---RGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPG--PPGPPGPPGLGG 108

Query: 956  ----------TPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA-ATPPSPKGGPATPS 1004
                            A       P  P G    P P GAP P      P   G P    
Sbjct: 109  NFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSG 168

Query: 1005 PKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATL 1064
            P G   PP   PP   G       P  A       PP P+G+       +G P TP   L
Sbjct: 169  PMGPRGPPG--PPGKPGDDGEAGKPGKAG---ERGPPGPQGA-------RGFPGTPG--L 214

Query: 1065 PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP--PAATP-----PSPKGGL 1117
            P  KG    P L GA     A  P  KG   +P   G+P P  P   P       P G  
Sbjct: 215  PGVKGHRGYPGLDGAKGEAGA--PGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAA 272

Query: 1118 ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPA-ATPPSPKGGLATPPPKGAPTTPA 1176
                + G P    A PP P G    P   GAP     A P   +G      P+G P TP 
Sbjct: 273  GARGNDGQP--GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG 330

Query: 1177 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT-PPSPKGGLATP 1235
            +  P P G    P   G         P  KG    P   GAP  P    PP P+G     
Sbjct: 331  S--PGPAGASGNPGTDGI--------PGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL 380

Query: 1236 SPKGAPTTPAAT----PPSPKGGPATPPPKGAPTPP-------AATPPSLKGGLATPPHK 1284
             PKG    P          PKG P    P+GAP P        A   P   G +  P  +
Sbjct: 381  GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 440

Query: 1285 GAPN----PAVVTPPSPKGGPATSPPKGAPTPPAAT-PPSPKGSPGTPPPKGAPTPPAVT 1339
            GAP     P       PKG P    P G   P  A   P   G PG P  +G    P   
Sbjct: 441  GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDA 500

Query: 1340 PPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK 1399
             P  K     P+  P   G P  P    GP      P   G P   P      P     K
Sbjct: 501  GPQGK---VGPSGAPGEDGRPGPP----GPQGARGQPGVMGFPG--PKGANGEPGKAGEK 551

Query: 1400 GDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATP 1459
            G P +P +  L  K          G A P+       A  P   +  P    P G    P
Sbjct: 552  GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP 611

Query: 1460 SSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPAT 1519
              +G           P E  AP  V     P+     P   G+P    +    P+ +P T
Sbjct: 612  GDQG----------VPGEAGAPGLV----GPRGERGFPGERGSPGAQGL--QGPRGLPGT 655

Query: 1520 PSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT-VPSPKKTPAIPTPK---------- 1568
            P           T   K       P  A  PP +  +P  +    I  PK          
Sbjct: 656  P----------GTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKG 705

Query: 1569 --EAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPA-VTSPSPKEAPTPPAVT-PPSP 1624
               AP     +  + P  + P    GA   K  + PP    S   + AP     T PP P
Sbjct: 706  PEGAPGKDGGRGLTGP--IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 763

Query: 1625 EKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEV 1684
                  P   G P +               A      GA  PQ   G P  +GPT +   
Sbjct: 764  AGFAGPPGADGQPGA---------KGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGP 814

Query: 1685 LVAPAPESTPIIT----APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLP 1740
              A   +  P  T    A  R GP     +   PP  P PS K+G KG      P     
Sbjct: 815  KGARGAQGPPGATGFPGAAGRVGPPGSNGN-PGPPGPPGPSGKDGPKGARGDSGP----- 868

Query: 1741 VQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSL 1800
                      G+      +GP  PP  K               +P     S A  PP   
Sbjct: 869  ---------PGRAGEPGLQGPAGPPGEKG--------------EPGDDGPSGAEGPPGPQ 905

Query: 1801 PLAPSPVPTLPPKQQFLPSSPGLVLES--PSKPLAPADEDELLPLIPPEP 1848
             LA        P Q+     PGL   S  P K  AP    +  P  P  P
Sbjct: 906  GLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGP 955



 Score =  164 bits (414), Expect = 1e-39
 Identities = 238/904 (26%), Positives = 267/904 (29%), Gaps = 284/904 (31%)

Query: 731  PKSVPSPSLPPAGTP-----PGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKG 785
            P   P P + PAG P     PG K   G   T A  P             GA       G
Sbjct: 283  PAGPPGP-VGPAGGPGFPGAPGAKGEAG--PTGARGP------------EGAQGPRGEPG 327

Query: 786  TLTYLADSPSPLGVSVSPQTKRPPTKKGSAG------------PDTPIG--NLSSPVSPV 831
            T      SP P G S +P T   P  KGSAG            P  P G    + P+ P 
Sbjct: 328  T----PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPK 383

Query: 832  EASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA-------------VTPLSPKGV 878
              +  P       G K        P P  P+GAP P+              V P+ P G 
Sbjct: 384  GQTGEP----GIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGE 439

Query: 879  TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKG 938
               P     P    L  PK  P    P          + PK A   P   G P  P  +G
Sbjct: 440  RGAPGNRGFPGQDGLAGPKGAPGERGPSGL-------AGPKGANGDPGRPGEPGLPGARG 492

Query: 939  APTPPAATPPSPKGGPA-TPSPKWAPTPPAATP----------PSPKGG---PATPSPKG 984
                P    P  K GP+  P     P PP              P PKG    P     KG
Sbjct: 493  LTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKG 552

Query: 985  APTPP-------------AATPPSPKGGPATPSPKGAPTPPAVT-------PPSPKGSPA 1024
             P  P             AA PP P G       +GAP P           PP   G P 
Sbjct: 553  LPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPG 612

Query: 1025 ATPFPKGASTPPAATP------PSPKGSPAATPL--PKGAPTTPAATLPSPKGGPATPSL 1076
                P  A  P    P      P  +GSP A  L  P+G P TP    P    GPA P  
Sbjct: 613  DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP- 671

Query: 1077 KGAPTPPA-------------ATPPSPKGGPATPSPKGAP-------MPPAATPPSPKG- 1115
             GA  PP              A P   +G      P+GAP       +     PP P G 
Sbjct: 672  -GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 730

Query: 1116 ----GLATPPH-------KGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT----PPSPK 1160
                G   PP        +GAP     T P    G A PP  GA   P A         K
Sbjct: 731  NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP--GADGQPGAKGEQGEAGQK 788

Query: 1161 GGLATPPPKGAPTTPAATPPS----PKGGLATPSPKGAPTTPAAT-------------PP 1203
            G    P P+G    P    P+    PKG      P GA   P A              PP
Sbjct: 789  GDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPP 848

Query: 1204 SPKGGLATPSPKGA-----------------PTTP--------------AATPPSPKG-- 1230
             P G      PKGA                 P  P              A  PP P+G  
Sbjct: 849  GPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLA 908

Query: 1231 ------GL----------ATPSPKGAPTTPAAT-------PPSPKGGPATPPPKGAP--- 1264
                  GL            P P G P    A        PP P G P    P G P   
Sbjct: 909  GQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGRE 968

Query: 1265 -TPPAATPPSLKGGLATPPHKGAPNPAVVTP--PSPKGGPATSPPKG------------- 1308
             +P A  PP   G       +G    AV  P  P P G P  + P G             
Sbjct: 969  GSPGADGPPGRDGAAGVKGDRGETG-AVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1027

Query: 1309 -APTPPAAT--------------------------------------PPSP---KGSPGT 1326
              P+ PA                                        PP P   +G+ G 
Sbjct: 1028 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1087

Query: 1327 PPPKGAPTPPAVTPPSPK-GTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385
              P G   PP    PS K G   +P   P    GP   S + GP  P   P   G P   
Sbjct: 1088 AGPSGPRGPPGPVGPSGKDGANGIPG--PIGPPGPRGRSGETGPAGPPGNPGPPGPPG-- 1143

Query: 1386 PPSP 1389
            PP P
Sbjct: 1144 PPGP 1147



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 165/696 (23%), Positives = 207/696 (29%), Gaps = 161/696 (23%)

Query: 1294 PPSPKGGPATSP----PKGAPTPPAATPPSPKGSPGTPPP---------KGAP------- 1333
            P   KG P        PKG        PP P+G  G   P         KGAP       
Sbjct: 33   PKGQKGEPGDIKDIVGPKG--------PPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDG 84

Query: 1334 ---TPPAVTPPSPKGTPTLPA----------------------------TTPSSKGGPTT 1362
               TP    PP P G P  P                               P    GP  
Sbjct: 85   EPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPG 144

Query: 1363 PSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTR 1422
            P+   GP      P   G P ++ P   RGP  P P G P          K     P   
Sbjct: 145  PAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP--PGPPGKPGDDGEAGKPGKAGERGPPGP 202

Query: 1423 EGAATPSKGDLTPPAVTPVSLKKA-PATSAPKGGPATPSSKGDPTLPAVT-PPSPKEP-- 1478
            +GA    +G    P +  V   +  P     KG    P  KG+   P     P P  P  
Sbjct: 203  QGA----RGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRG 258

Query: 1479 ---------PAPKQVATSSSPKKAPATP----APMGAPTLPAVIPSSPKEVPATPSSRRD 1525
                     PA    A  +  +  PA P     P G P  P   P +  E  A P+  R 
Sbjct: 259  LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGA-PGAKGE--AGPTGARG 315

Query: 1526 PIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV 1585
            P           TP +  P  A   P         T  IP  K +   P    A +P   
Sbjct: 316  PEGAQGPRGEPGTPGSPGPAGASGNPG--------TDGIPGAKGSAGAPGI--AGAP--- 362

Query: 1586 TPSTYKGAPSPKELLIPPAVTSP-SPKEAPTPPAVTPPSPEKGP-ATPAPKGTPTSP-PV 1642
                  G P P+    P   T P  PK     P +     E+GP   P P G   +P P 
Sbjct: 363  ------GFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA 416

Query: 1643 TPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRK 1702
                 + +   P  V    G   P   +G P  +G    ++ L  P         AP  +
Sbjct: 417  GEEGKRGARGEPGGV----GPIGPPGERGAPGNRGFPG-QDGLAGPK-------GAPGER 464

Query: 1703 GPQ--TKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKG 1760
            GP        A   P  P      G++G   T  P    P  K     A G+D    P G
Sbjct: 465  GPSGLAGPKGANGDPGRPGEPGLPGARG--LTGRPGDAGPQGKVGPSGAPGEDGRPGPPG 522

Query: 1761 P---------LAPPESKASTPLTAAAFEKVLP-------KPESASVSAAPSPPVSLPLAP 1804
            P         +  P  K +      A EK LP        P     + A  PP   P  P
Sbjct: 523  PQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG--PAGP 580

Query: 1805 S-----------------PVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPE 1847
            +                 P P  PP +   P   G+  E+ +  L     +   P     
Sbjct: 581  AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS 640

Query: 1848 PISGGVPFQSVLVNMP---TPKSAGIPVPTPSAKQP 1880
            P + G+     L   P    PK A  P   P A+ P
Sbjct: 641  PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGP 676



 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 108/469 (23%), Positives = 154/469 (32%), Gaps = 73/469 (15%)

Query: 1338 VTPPSPKGTPTLPATT-----PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392
            V  P PKG    P        P    GP  P+ ++GP         KG P       + G
Sbjct: 28   VRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPG 87

Query: 1393 -PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSA 1451
             P  P P G P  P    L    A       +  A  ++  +    + P+  +  P  + 
Sbjct: 88   TPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAG 147

Query: 1452 PKGGPATPSSKGDPTLPAVT-PPSPKEPPAPK----QVATSSSPKKA--PATPAPMGA-- 1502
              G      + G+P  P V+ P  P+ PP P         +  P KA     P P GA  
Sbjct: 148  APGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARG 207

Query: 1503 ----PTLPAVIPSSPKEVPATPSSRRDPIAP-----TATLLSKKTPATLAPKEALIPPAM 1553
                P LP V     +  P    ++ +  AP     + +     +P  + P+        
Sbjct: 208  FPGTPGLPGV--KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGR 265

Query: 1554 TVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEA 1613
            T P+          +  PA P        PA  P  + GAP  K    P     P   + 
Sbjct: 266  TGPAGAAGARGNDGQPGPAGPPGPVG---PAGGPG-FPGAPGAKGEAGPTGARGPEGAQG 321

Query: 1614 PTPPAVTPPSPEKGPA----------TPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGA 1663
            P     TP SP  GPA           P  KG+  +P +  +     P  P       GA
Sbjct: 322  PRGEPGTPGSP--GPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPG---PQGA 376

Query: 1664 TVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAK 1723
            T P   KG   + G    K                   +GP+ +   A  P   P P+ +
Sbjct: 377  TGPLGPKGQTGEPGIAGFK-----------------GEQGPKGEPGPA-GPQGAPGPAGE 418

Query: 1724 NGSKGPLSTVAPAPLLPVQKDSSKTA------KGKDASHSPKGPLAPPE 1766
             G +G  +   P  + P+     + A       G+D    PKG  AP E
Sbjct: 419  EGKRG--ARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKG--APGE 463


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score =  221 bits (562), Expect = 8e-57
 Identities = 360/1445 (24%), Positives = 513/1445 (35%), Gaps = 251/1445 (17%)

Query: 754  ISHTSALAPVASSPKECPT----EDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPP 809
            +S  +AL+ V+S   +        DS AS   ++K       +   P G+   P  ++PP
Sbjct: 157  LSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPP 216

Query: 810  T---KKGSAGPD------TPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS 860
                K+   G D      TP  ++SS       S  P      QG   +P T H+  P  
Sbjct: 217  KPIPKQQGPGRDPLQQDGTP-KSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQ 275

Query: 861  PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK 920
             + A  P        +G ++ P   P+PS    P  +  P  P P Q P    +   P K
Sbjct: 276  -RDASRPQTKQADIVRGESVKPS-LPSPS--KPPIQQPTPGKP-PAQQPGHEKSQPGPAK 330

Query: 921  ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATP 980
              A P+    P +  P G   PP   PP     PA   P     PPA    S K     P
Sbjct: 331  PPAQPSGLTKPLAQQP-GTVKPPVQ-PPGTTKPPA--QPLGPAKPPAQQTGSEKPSSEQP 386

Query: 981  SPKGAPTPPAA-TPPSPKGGPATPSPK--GAPTPPAVTP--PSPKGSPAATPFPKGASTP 1035
             PK    PP     P+ + GPA P  +  G P P A  P   SP  +P  T  P     P
Sbjct: 387  GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP--VQQP 444

Query: 1036 PAATPPSPKGSPAATPLPKGAPTTPAATLPSP------KGGPATPSLK--GAPTPPAATP 1087
                 P+ +  P  T   +  PT P + LP P      + GPA P  +  G+  PP+  P
Sbjct: 445  GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP 504

Query: 1088 PSPKGGPATPSP-KGAPMPPAAT-PPSPKGGLATP----PHKGAPTTPAATPPSPKGGLA 1141
             S K  P  P P K +P  P +T PPS + G A P    P    P+   +T P  + G  
Sbjct: 505  GSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG-- 562

Query: 1142 TPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT-TPAA 1200
                 G P  P    PS K     PP +G P T      + +  L  P      T T   
Sbjct: 563  ----SGKPLQPPTVSPSAK----QPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQ 614

Query: 1201 TPPSPKGGLATPSPK------------------GAPTTPAATPPSPKGGLATPSPKGAP- 1241
            T      G   P+P                   G    P  + P PK        K AP 
Sbjct: 615  TTVCSLCGF-NPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK-------LKTAPV 666

Query: 1242 -TTPAATPPSPKGGPATPPPKGAP------TPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294
             TT A +  SP+    +P    AP       P    PP L   +  P   G+P+     P
Sbjct: 667  TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPL---VKQPTLHGSPSAKAKQP 723

Query: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA-PTPPAVTPPSPKGTPTLPATT 1353
            P        +PPK  P+ P+    +P        PK   PT   V+  S    P +P++ 
Sbjct: 724  PEADSLSKPAPPK-EPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSK 782

Query: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGP----AIPSPKGDPTSPAVIP 1409
              S+       ++E  TPP  T S K   +  P   K  P    AIP P  D        
Sbjct: 783  VQSQ-------AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD-------- 827

Query: 1410 LSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGP---ATPSSKGDPT 1466
                   +  ++  G ++ SKG      V PV  K+ P  +  K  P   A P  KG PT
Sbjct: 828  -------SKIISHPGPSSESKGQ---KQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPT 877

Query: 1467 LPAVTP------PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP------------AV 1508
             P   P      P+P++ P P++ +   S      T AP   PT P            A 
Sbjct: 878  PPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGAS 937

Query: 1509 IPSSPKEVPAT-----PSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT---VPSPKK 1560
            I S    + +T     P S+  P AP      K+ PA   P  +  PP  T    P+P K
Sbjct: 938  IFSQASNLISTAGQPGPHSQSGPGAP-----MKQAPAPSQPPTSQGPPKSTGQAPPAPAK 992

Query: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620
              +IP  KE  A  + K    P A    T K   + K+   PP +       A    AV 
Sbjct: 993  --SIPVKKETKAPAAEK--LEPKAEQAPTVKRTETEKK---PPPIKDSKSLTAEPQKAVL 1045

Query: 1621 PPSPEKGPATPAPKGT-PTSPPVTPSSLKDSPTSPASVTCK------------------- 1660
            P   EK   +P P+ T P          KD P       CK                   
Sbjct: 1046 PTKLEK---SPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQ 1102

Query: 1661 ----MGATVPQASKGL--PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSP 1714
                +     +A  G     +K P A      +P P  T   +  T   PQ K       
Sbjct: 1103 EWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQ 1162

Query: 1715 PICPDPS----AKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAS 1770
             +  +       K      +  + P      +++ SK  K K ++   K PL  PE K  
Sbjct: 1163 EVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPL--PEEKKL 1220

Query: 1771 TPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSK 1830
             P      EK+  + +   +      P    L P    + P +Q+              K
Sbjct: 1221 IP----EEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQK----------HDLLK 1266

Query: 1831 PLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGT 1890
                  E++L   + P+ +  G          P  K  G+P  TP +             
Sbjct: 1267 SQVQIAEEKLEGRVAPKTVQEG--------KQPQTKMEGLPSGTPQS------------L 1306

Query: 1891 ESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEK-KARKAMSKLGL- 1948
              + D++   ++EQ     T +  Q+    E  E+   K+  S S++ K+ + +S  G  
Sbjct: 1307 PKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYS 1366

Query: 1949 -----RQVTGVTRVTIRKSKNILFVITKPDVYK--SPASDTYIVFGEAKI-EDLSQQAQL 2000
                   +  +  +     K+IL  + K    +  SP+S + +   E+ +   L  QA  
Sbjct: 1367 SDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQAST 1426

Query: 2001 AAAEKF--KVQGEAVS----NIQENTQ--TPTVQEESEEEEVDETGVEVKDIELVMSQAN 2052
             A EK   K Q   VS      QE TQ  + T++    EEE+ E+  E KD     SQ +
Sbjct: 1427 LADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQD 1486

Query: 2053 VSRAK 2057
            +  +K
Sbjct: 1487 IPSSK 1491



 Score =  176 bits (446), Expect = 2e-43
 Identities = 328/1410 (23%), Positives = 471/1410 (33%), Gaps = 240/1410 (17%)

Query: 543  PFSPAQAGLTTKKDPTVLPLVQAAPKNSPS---FQSTSSSPEIPLSPEATLAKKSLGEPL 599
            P  PAQ GL+  +        Q  P  SPS    + + S  ++    ++++    L E  
Sbjct: 102  PGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVN 161

Query: 600  PIGKPASSMTS----PLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFP---LES 652
             +   +S +       L  +S AS  +T                +I P +   P   +  
Sbjct: 162  ALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPK 221

Query: 653  ADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAP-KNHPVKEGTLTTLPLVPTASENCPVA 711
                G  P    GT    ++  P  E   S  P    P++  T T      T     P+ 
Sbjct: 222  QQGPGRDPLQQDGTPKSISSQQP--EKIKSQPPGTGKPIQGPTQTP----QTDHAKLPLQ 275

Query: 712  PSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECP 771
                      A +V    +  S+PSPS PP   P   K            P A  P    
Sbjct: 276  RDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK------------PPAQQPGHEK 323

Query: 772  TEDSGASATASSKGTLTYLADSPSPLGVSVSPQ-TKRPPTKKGSAGPDTPIGNLSSPVSP 830
            ++   A   A   G    LA  P  +   V P  T +PP +    GP  P    +    P
Sbjct: 324  SQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQP--LGPAKPPAQQTGSEKP 381

Query: 831  VEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAV-------TPLSPKGVTLPPK 883
                  P+      G   +PA    P  P  +   TP  +       +P    G T  P 
Sbjct: 382  SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441

Query: 884  ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP 943
            + P P    +P  + GP   + +Q       S  P  A+  P   G PA P P+    P 
Sbjct: 442  QQPGPG--KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPG-PAKPPPQ---QPG 495

Query: 944  AATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP 1003
            +A PPS + G   P P+  P P   +P  P G    PS +     P+A  PS    PA P
Sbjct: 496  SAKPPSQQPGSTKPPPQ-QPGPAKPSPQQP-GSTKPPSQQPGSAKPSAQQPS----PAKP 549

Query: 1004 SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAAT 1063
            S + +  P + T     G P   P     +  P+A  P  +G P  T  P    T     
Sbjct: 550  SAQQSTKPVSQT---GSGKPLQPP-----TVSPSAKQPPSQGLP-KTICPLCNTTELLLH 600

Query: 1064 LPSPKGGPATPSLKGAPTPPAATPPSPKGGPA---------TPSPKGAPMPPAATPPSPK 1114
            +P           +          P+P                   G  + P  + P PK
Sbjct: 601  VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK 660

Query: 1115 GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPP------ 1168
              L T P     TT A +  SP+    +P    AP    +  P PK     PPP      
Sbjct: 661  --LKTAP---VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPK----KPPPLVKQPT 711

Query: 1169 -KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA-PTTPAATPP 1226
              G+P+  A  PP     L+ P+P   P+ P+    +P        PK   PTT   +  
Sbjct: 712  LHGSPSAKAKQPPE-ADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSS 770

Query: 1227 SPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGA 1286
            S       PS K        T P  K   A P     PT    +P   K   A P  + A
Sbjct: 771  SATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSK---AIP--RPA 825

Query: 1287 PNPAVVTPPSP----KGGPATSPPKGAPTP-PAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341
             +  +++ P P    KG     P +    P  A T  SPK     P PKG+PTPP   P 
Sbjct: 826  SDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPK-PDAKPMPKGSPTPPGPRPT 884

Query: 1342 SPKGTPTLPATTP---------SSKGGPTTPSSKEGPTPPAATPSHK---GGPAMTPPSP 1389
            + +  PT P  +P         S   G  T + K  PT P  T + K    G ++   + 
Sbjct: 885  AGQTVPT-PQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQAS 943

Query: 1390 KRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT 1449
                    P     S    P+    AP+ P T +G    S G   P     + +KK   T
Sbjct: 944  NLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQG-PPKSTGQAPPAPAKSIPVKK--ET 1000

Query: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509
             AP      P ++  PT+   T    K PP     + ++ P+KA           LP  +
Sbjct: 1001 KAPAAEKLEPKAEQAPTVKR-TETEKKPPPIKDSKSLTAEPQKA----------VLPTKL 1049

Query: 1510 PSSPKEVPATPSSR-------RDP------------------IAPTATL--------LSK 1536
              SPK     P  +       +DP                    PT  L        L+ 
Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNC 1109

Query: 1537 KTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV----------- 1585
            +T   ++ +   I      PS  K   +P P E+    SS++ + PP V           
Sbjct: 1110 QTQRAISGQLGDIRKMPPAPSGPKASPMPVPTES----SSQKTAVPPQVKLVKKQEQEVK 1165

Query: 1586 TPSTYKGAPSPKELL----IPPAVTS---------------------PSPKEAP-TPPAV 1619
            T +        KE L    IPP VT+                     P P+E    P   
Sbjct: 1166 TEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEE 1225

Query: 1620 TPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ-------ASKGL 1672
               S EK P     K TP    + P +   +P        K    + +       A K +
Sbjct: 1226 KIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTV 1285

Query: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLST 1732
               K P    E L +  P+S P            K+   T+  I   P        P  T
Sbjct: 1286 QEGKQPQTKMEGLPSGTPQSLP------------KEDDKTTKTIKEQPQ-------PPCT 1326

Query: 1733 VAPAPLLPVQKDSSKTAKGKDASHS--PKGPLAPPESKASTPLTAAAFEKV---LP---- 1783
              P  + P ++ + K     D S S  PK P    ++  S+   +++  ++   +P    
Sbjct: 1327 AKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEK 1386

Query: 1784 ------KPESASVSAAPSPPVSLPLAPSPV 1807
                  K +S S  ++PS P  L    S V
Sbjct: 1387 DILKGLKKDSFSQESSPSSPSDLAKLESTV 1416



 Score =  146 bits (369), Expect = 2e-34
 Identities = 307/1322 (23%), Positives = 424/1322 (32%), Gaps = 207/1322 (15%)

Query: 561  PLVQAAPKNSPSFQSTSSSP----EIPLSPEATLAKKSLGEPLPIGKPASSMTS------ 610
            PL Q  PK  P  Q     P      P S  +   +K   +P   GKP    T       
Sbjct: 210  PLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269

Query: 611  ---PLGVNSSASVIKTDSYAGPDSAGPLL----KSSLITPTVAAFPLESADPAGVAPTTA 663
               PL  ++S    K       +S  P L    K  +  PT    P +        P  A
Sbjct: 270  AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329

Query: 664  KGTSTYTTTASPFLEGTVSLAPKNHP---VKEGTLTTLPLVPTASENCPVAPSPQNTCAP 720
            K  +  +    P  +   ++ P   P    K       P  P A +     PS +    P
Sbjct: 330  KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP-GP 388

Query: 721  LATLVLAPEI---PKSVPSPSLPPA---GTPPGTKKVDGI-SHTSALAPVAS-----SPK 768
             A L   P +   P   P P+ PP    GTP    +  G+ S   A  P  +      P 
Sbjct: 389  KA-LAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG 447

Query: 769  ECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQ------TKRPPTKKGSAGPDT--P 820
            + P + +G   T++ +   T     PS L     P        K PP + GSA P +  P
Sbjct: 448  KIPAQQAGPGKTSAQQ---TGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP 504

Query: 821  IGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH-SPTPPSPKGAPTPSAVTPLSPKGVT 879
                  P  P  A   P+   S +     P +   S   PSP       +  P+S  G +
Sbjct: 505  GSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG-S 563

Query: 880  LPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSS----PKKAR-------ATPAPK 928
              P + PT S    P  K+ P+   PK    L  T+      P+KA         T    
Sbjct: 564  GKPLQPPTVS----PSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCS 619

Query: 929  GIPASPSPK------------------GAPTPPAATPPSPK--GGPATPSPKWAPTPPAA 968
                +P+P                   G    P  + P PK    P T       T  A 
Sbjct: 620  LCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVT-------TTSAV 672

Query: 969  TPPSPKGGPATPSPKGAPTPPAATPPSPKGGP---ATPSPKGAPTPPAVTPPSPKGSPAA 1025
            +  SP+    +P    AP    +  P PK  P     P+  G+P+  A  PP       A
Sbjct: 673  SKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE------A 726

Query: 1026 TPFPKGASTPPAATPPSPKGSPAATPLPKG----APTTPAATLPSPKGGPATPSLKGAPT 1081
                K A     + P     +P A   PK      PTT   +  S    P  PS K    
Sbjct: 727  DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQ 786

Query: 1082 PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP-PHKGAPTTPAATPPSPKGG- 1139
                T P  K   A PS      PP     SP    A P P   +       P S   G 
Sbjct: 787  AEEKTTPPLKTDSAKPSQS---FPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQ 843

Query: 1140 -LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198
                P  K      A T  SPK   A P PKG+PT P    P P  G   P+P+ +P   
Sbjct: 844  KQVDPVQKKEEPKKAQTKMSPKPD-AKPMPKGSPTPPG---PRPTAGQTVPTPQQSPKPQ 899

Query: 1199 AATPP-SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPAT 1257
              +   S   G  T +PK  PTTP  T      G    S     +   +T   P  GP +
Sbjct: 900  EQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA-SIFSQASNLISTAGQP--GPHS 956

Query: 1258 PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP 1317
                GAP   A  P         P  +G P      PP+P     + P K     PAA  
Sbjct: 957  QSGPGAPMKQAPAPSQ------PPTSQGPPKSTGQAPPAP---AKSIPVKKETKAPAAEK 1007

Query: 1318 PSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPS 1377
              PK       P    T     PP  K + +L A  P     PT    ++ P P +  P 
Sbjct: 1008 LEPKAEQA---PTVKRTETEKKPPPIKDSKSLTA-EPQKAVLPT--KLEKSPKPESTCPL 1061

Query: 1378 HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP-----KKAPATPVTREGAATPSKGD 1432
             K    +    P         K    +      +P     ++        + A +   GD
Sbjct: 1062 CKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGD 1121

Query: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKK 1492
            +          K  PA S PK  P    ++      AV P         ++V T +    
Sbjct: 1122 IR---------KMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVI 1172

Query: 1493 APATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPA 1552
                   +    +P ++ +  K+  +     +      A+ L +K P  L  ++ LIP  
Sbjct: 1173 LEKVKETLSMEKIPPMVTTDQKQEESKLEKDK------ASALQEKKP--LPEEKKLIPEE 1224

Query: 1553 MTVPSPKKTPAI----PTPKEAPATPSSK-------------------EASSPPAVTPST 1589
              + S +K P +    PTP++    P +K                   E      V P T
Sbjct: 1225 EKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKT 1284

Query: 1590 ----------YKGAPS--PKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637
                       +G PS  P+ L      T+ + KE P PP    P        P  + T 
Sbjct: 1285 VQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPD----QVEPGKEKTE 1340

Query: 1638 TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697
                 + +S    P SP  +     +    +S G+ +  G            P   P   
Sbjct: 1341 KEDDKSDTSSSQQPKSPQGL-----SDTGYSSDGISSSLG----------EIPSLIPTDE 1385

Query: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757
                KG +    S  S P  P   AK  S       A A  L  +K   KT   + +   
Sbjct: 1386 KDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQ 1445

Query: 1758 PK 1759
            PK
Sbjct: 1446 PK 1447



 Score = 88.6 bits (218), Expect = 6e-17
 Identities = 204/939 (21%), Positives = 296/939 (31%), Gaps = 180/939 (19%)

Query: 13   EQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPST 72
            +++  +PQ + A +    ++  +     P P+ PP   P P + P          P P+ 
Sbjct: 275  QRDASRPQTKQADIVRGESVKPSL----PSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAK 330

Query: 73   IASTPLEVPFPQSSSGTALPLGTAP---EAPTFLPNLIGPPISPAALALASPMIAPTLKG 129
              + P         SG   PL   P   + P   P    PP  P  L  A P    T   
Sbjct: 331  PPAQP---------SGLTKPLAQQPGTVKPPVQPPGTTKPPAQP--LGPAKPPAQQTGSE 379

Query: 130  TPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLN 189
             PSS  P                  P  L  PP V         T +    P++P T   
Sbjct: 380  KPSSEQP-----------------GPKALAQPPGVGK-------TPAQQPGPAKPPTQQV 415

Query: 190  KVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDT 249
              P  +   P G  SP    +  P    TP+     G     Q  P  T           
Sbjct: 416  GTPKPLAQQP-GLQSP----AKAPGPTKTPVQQPGPGKIPAQQAGPGKT----------- 459

Query: 250  TISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHL 309
              S+    P  P S  L GP  PP                 +  GP  PP  P   GS  
Sbjct: 460  --SAQQTGPTKPPS-QLPGPAKPP----------------PQQPGPAKPP--PQQPGSAK 498

Query: 310  APLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPA 369
             P  Q    +     Q GP+  S     +        G++ PS +   P  PS      A
Sbjct: 499  PPSQQPG-STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS------A 551

Query: 370  TVAAFPVVAPSVDK--GPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPL 427
              +  PV      K   P T+S     P       T   L  TT L+L     A ++   
Sbjct: 552  QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611

Query: 428  VAQMPVSSV-GTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMA 486
              Q  V S+ G  P    NP        T  +   C++  M      ++ P      V +
Sbjct: 612  ECQTTVCSLCGFNP----NP------HLTEVKEWLCLNCQMKRALGGDLAP------VPS 655

Query: 487  PVAPKEPSTQVATTLRIPVSPPLPDPEDLKN--LPSSVLVKFPTQKDLQTVPASLEGAPF 544
               PK  +  V TT  +  S P P     K    P   L K P  K     P  L   P 
Sbjct: 656  SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK----PPPLVKQPT 711

Query: 545  SPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKP 604
                     K+ P    L + AP   PS  S           +A +A     +P  + KP
Sbjct: 712  LHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQD--------KAPVADDKPKQPKMV-KP 762

Query: 605  ASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAK 664
             + +     V+SS++  K      PD     ++S     T      +SA P+   P T +
Sbjct: 763  TTDL-----VSSSSATTK------PDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGE 811

Query: 665  GTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATL 724
              S + + A P             P  +  + + P   + S+        Q    P    
Sbjct: 812  KVSPFDSKAIP------------RPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQ 859

Query: 725  VLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSK 784
                  P + P P   P  TPPG +   G            +P++ P     +   + + 
Sbjct: 860  TKMSPKPDAKPMPKGSP--TPPGPRPTAG--------QTVPTPQQSPKPQEQSRRFSLNL 909

Query: 785  GTLTYLADSPSP---------------LGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVS 829
            G++T   D+P                  G S+  Q     +  G  GP +     S P +
Sbjct: 910  GSIT---DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ----SGPGA 962

Query: 830  PVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPS 889
            P++ +  P    + QG    P  +    PP+P     P      +P    L PK    P+
Sbjct: 963  PMKQAPAPSQPPTSQG----PPKSTGQAPPAP-AKSIPVKKETKAPAAEKLEPKAEQAPT 1017

Query: 890  VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPK 928
            V      K+ P     K   A    +  P K   +P P+
Sbjct: 1018 VKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE 1056



 Score = 78.2 bits (191), Expect = 8e-14
 Identities = 130/571 (22%), Positives = 189/571 (33%), Gaps = 86/571 (15%)

Query: 723  TLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVA---------SSPKECPTE 773
            +L+L    P S  + S+PP+ TP  T  V  +  T + +P+          + P +  T+
Sbjct: 2161 SLILTYSEP-SESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITK 2219

Query: 774  DSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEA 833
               +   +SS      + D P  + VS+     R     G A  D  + +LS   S +  
Sbjct: 2220 FEDSEEISSSTYFPGSIIDYPEEISVSLD----RTAPPDGRASADHIVISLSDMASSIIE 2275

Query: 834  SFL--PENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPL-------------SPKGV 878
            S +  PE  ++   S D   +   P   + K       +  L             +   +
Sbjct: 2276 SVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSL 2335

Query: 879  TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP-- 936
            +    + P  SV+ LP  KE  +T              + +    +P+   +PA P P  
Sbjct: 2336 SETVFDHPPSSVIALPM-KEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFF 2394

Query: 937  KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSP 996
            + +    +A PP P   P  P     P PP   PP P   P +P P           P  
Sbjct: 2395 RSSSLDISAQPPPPPPPPPPP-----PPPPPPPPPPPLPPPTSPKP--------TILPKK 2441

Query: 997  KGGPATPSPKGAPTPPAVTPPSPKG--SPAATPFPKGASTPPAATPPSPKGSPAA----- 1049
            K   A+P     P   AVT             P  +  +T P   PP P   P+      
Sbjct: 2442 KLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTH 2501

Query: 1050 TPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPS-------PKGA 1102
             P P   P  P          P  P L      P    P P G   T S           
Sbjct: 2502 RPEPSKPPIAPK---------PVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADY 2552

Query: 1103 PMPPAATPPSPKGGLATPPHKGA--PTTPAATPPSPKGGLATPPPKGAPTTPAATP-PSP 1159
             +P   +P SP    ++P    +   T    T PS  G   TP    A     + P  SP
Sbjct: 2553 KLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPG---TPTDSSASQAITSWPLGSP 2609

Query: 1160 KGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1219
               L +  P  +   P      P     T    GA  T +ATP +            AP+
Sbjct: 2610 SKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVT------------APS 2657

Query: 1220 TPAATPPSPKGGLATPSPKGAPTTPAATPPS 1250
            +  A P S    L T   K   +   +T PS
Sbjct: 2658 SFQAAPTSVTQFLTTEVSKTEVSATRSTAPS 2688



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 235/1064 (22%), Positives = 344/1064 (32%), Gaps = 196/1064 (18%)

Query: 17   PQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPL-------SAANQASPFPS 69
            P  Q      P++    + +    PGPT  P   P P + P        ++A Q  P   
Sbjct: 410  PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469

Query: 70   PSTIASTPLEVPFPQSSSGTALPLGTAP---EAPTFLPNLIGPPISPAALALASPMIAPT 126
            PS +   P     P    G A P    P   + P+  P    PP      A  SP    +
Sbjct: 470  PSQL---PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526

Query: 127  LKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKT 186
             K  P S  P      A  S Q+ S   P+   S   V+   SG       P+ P     
Sbjct: 527  TK--PPSQQP----GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK------PLQPPTVSP 574

Query: 187  NLNKVPSEVVPNPKGTPSPPCIVSTVPYH------------CVTPMASIQSGVASLPQTT 234
            +  + PS+ +P    T  P C  + +  H            C T + S+  G    P  T
Sbjct: 575  SAKQPPSQGLPK---TICPLCNTTELLLHVPEKANFNTCTECQTTVCSL-CGFNPNPHLT 630

Query: 235  PTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAG 294
                    + Q+K      +   P +P       PV+  +A+S S+   P  TS +K A 
Sbjct: 631  EVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQ-PQQTSPKKDAA 689

Query: 295  PNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVK--TISVDHSSTGASYPS 352
            P                         Q L +        P VK  T+    S+     P 
Sbjct: 690  PK------------------------QDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE 725

Query: 353  QRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTS 412
              S+  P P +   VP+     P VA    K P  +                    PTT 
Sbjct: 726  ADSLSKPAPPKEPSVPSEQDKAP-VADDKPKQPKMV-------------------KPTTD 765

Query: 413  LILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPI 472
            L+  SS       P       +   TTP + T+    +A P+ +F        P  S  I
Sbjct: 766  LVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTD----SAKPSQSFPPTGEKVSPFDSKAI 821

Query: 473  SNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDL 532
                P S + ++  P    E   Q              DP   K  P     K   + D 
Sbjct: 822  P--RPASDSKIISHPGPSSESKGQKQV-----------DPVQKKEEPKKAQTKMSPKPDA 868

Query: 533  QTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQS----------TSSSPEI 582
            + +P      P     AG T       +P  Q +PK  P  QS          T +    
Sbjct: 869  KPMPKGSPTPPGPRPTAGQT-------VPTPQQSPK--PQEQSRRFSLNLGSITDAPKSQ 919

Query: 583  PLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLIT 642
            P +P+ T+  K  G    I   AS++ S  G           S +GP    P+ ++   +
Sbjct: 920  PTTPQETVTGKLFGFGASIFSQASNLISTAGQPG------PHSQSGP--GAPMKQAPAPS 971

Query: 643  -PTVAAFPLESADPAGVAPTTAKGTSTYTTTASPF---LEGTVSLAP---------KNHP 689
             P  +  P +S   A  AP  AK       T +P    LE     AP         K  P
Sbjct: 972  QPPTSQGPPKSTGQAPPAP--AKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPP 1029

Query: 690  VKEG-TLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGT 748
            +K+  +LT  P           +P P++TC PL    L      ++ S   P   T    
Sbjct: 1030 IKDSKSLTAEPQKAVLPTKLEKSPKPESTC-PLCKTEL------NIGSKDPPNFNTCTEC 1082

Query: 749  K----KVDGISHTSALAPVAS-SPKECPTEDSGASATASSKGTLTYLADSP-----SPLG 798
            K     + G + T  L  +       C T+     A +   G +  +  +P     SP+ 
Sbjct: 1083 KNQVCNLCGFNPTPHLTEIQEWLCLNCQTQ----RAISGQLGDIRKMPPAPSGPKASPMP 1138

Query: 799  V---SVSPQTKRPP----TKKGSAGPDTPIGNL----------SSPVSPVEASFLPENSL 841
            V   S S +T  PP     KK      T    +             + P+  +   +   
Sbjct: 1139 VPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEES 1198

Query: 842  SFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPA 901
              +  K S      P P   K  P    +   S +   L  ++ PTP    L  P+   +
Sbjct: 1199 KLEKDKASALQEKKPLPEEKKLIPEEEKIR--SEEKKPLLEEKKPTPEDKKL-LPEAKTS 1255

Query: 902  TPAPKQAPAL-SMTSSSPKKARATPAPKGIPASPSPKGAPTP-PAATPPS-PK-GGPATP 957
             P  ++   L S    + +K     APK +     P+      P+ TP S PK     T 
Sbjct: 1256 APEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTK 1315

Query: 958  SPKWAPTPPAATPP---SPKGGPATPSPKGAPTPPAATPPSPKG 998
            + K  P PP    P    P           + T  +  P SP+G
Sbjct: 1316 TIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQG 1359



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 124/510 (24%), Positives = 182/510 (35%), Gaps = 90/510 (17%)

Query: 1472 PPSPKEPPAP--KQVATSSSPKKAPATPAPMGAPTLPAVIPS-------SPKEVPA-TPS 1521
            PP+  E P+   KQ   SS P K    P   G P  P +  S       S +++P  +PS
Sbjct: 72   PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPS 131

Query: 1522 SRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASS 1581
            +     + + T L ++  +++ P       A++  S       P    + +  S +E + 
Sbjct: 132  TISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTK 191

Query: 1582 PPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAP--------------TPPAVTPPSPEKG 1627
               V     K    P+ ++ PP    P PK  P              TP +++   PEK 
Sbjct: 192  KQKV---VQKEQGKPEGIIKPPLQQQP-PKPIPKQQGPGRDPLQQDGTPKSISSQQPEKI 247

Query: 1628 PATPAPKGTPTSPPV-TPSSLKDSPTSPASVTCKMGATVPQAS-----KGLPAKKG-PTA 1680
             + P   G P   P  TP       T  A +  +  A+ PQ       +G   K   P+ 
Sbjct: 248  KSQPPGTGKPIQGPTQTPQ------TDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP 301

Query: 1681 LKEVLVAPAPESTPI------ITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVA 1734
             K  +  P P   P        + P    P  + S  T P      + K   + P +T  
Sbjct: 302  SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKP 361

Query: 1735 PA-PLLPVQKDSSKTAKGKDASHSP------------------KGPLAPPESKASTPLTA 1775
            PA PL P +  + +T   K +S  P                   GP  PP  +  TP   
Sbjct: 362  PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTP--- 418

Query: 1776 AAFEKVLPKPESASVSAAPSP---PVSLPLAPSPVPTL---PPK---QQFLPSSPGLVLE 1826
               + +  +P   S + AP P   PV  P  P  +P     P K   QQ  P+ P   L 
Sbjct: 419  ---KPLAQQPGLQSPAKAPGPTKTPVQQP-GPGKIPAQQAGPGKTSAQQTGPTKPPSQLP 474

Query: 1827 SPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTP----SAKQPVT 1882
             P+KP  P  +       P +P S   P Q      P P+  G   P+P    S K P  
Sbjct: 475  GPAKP--PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP-- 530

Query: 1883 KNNKGSGTESDSDESVPELEEQDSTQATTQ 1912
                GS   S    S  +   Q ST+  +Q
Sbjct: 531  SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560



 Score = 73.2 bits (178), Expect = 3e-12
 Identities = 81/315 (25%), Positives = 123/315 (39%), Gaps = 43/315 (13%)

Query: 1297 PKGGPATSPPKGAPTP--------PAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPT 1348
            P G P+ S     P P         +A PP P   P  PPP   P PP   PP P  T  
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP---PPLPPPTSP 2433

Query: 1349 LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI 1408
             P   P  K    +P +        ATP       +   +  R   +P  +   T+P  +
Sbjct: 2434 KPTILPKKKLTVASPVT-------TATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPV 2486

Query: 1409 PLSPKKAPATPVTREGAATPSKGDLTPPAVTP--VSLKKAPATSAPKGGPATPSSKGDPT 1466
            P  P   P+  V       PSK  + P  V P   +  + P    PK  P   S     T
Sbjct: 2487 PPKPSSIPSGLVFTH-RPEPSKPPIAPKPVIPQLPTTTQKPTDIHPK--PTGLSLTSSMT 2543

Query: 1467 LPAVTP-----PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPS 1521
            L  VT      PSP  P +P   +  SSP+ + +        TLP+  P +P +  A+ +
Sbjct: 2544 LNLVTSADYKLPSPTSPLSPH--SNKSSPRFSKSLTETYVVITLPSE-PGTPTDSSASQA 2600

Query: 1522 SRRDPI-APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEAS 1580
                P+ +P+  L+S      + P  +++PP   V  P     I + +    + + +  S
Sbjct: 2601 ITSWPLGSPSKDLVS------VEPVFSVVPPVTAVEIP-----ISSEQTFYISGALQTFS 2649

Query: 1581 SPPAVTPSTYKGAPS 1595
            + P   PS+++ AP+
Sbjct: 2650 ATPVTAPSSFQAAPT 2664



 Score = 73.2 bits (178), Expect = 3e-12
 Identities = 129/531 (24%), Positives = 209/531 (39%), Gaps = 100/531 (18%)

Query: 41   PGPTLPPPCSPAPQQCPLSAANQASPFPSPSTI--ASTPLEVPFPQSSSG---TALPLGT 95
            P P LPPP SP P   P      ASP  + + +  A T LE      S+G   T +    
Sbjct: 2423 PPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTA 2482

Query: 96   APEAP------------TFLPNLIGPPISPAALALASPM-------IAPTLKG-TPSSSA 135
             P  P            T  P    PPI+P  +    P        I P   G + +SS 
Sbjct: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSM 2542

Query: 136  PLALVALAPHSV-QKSSAFPPNLLTSPP--SVAVAESGSVITLSAPIAPSEPKTNLNKVP 192
             L LV  A + +   +S   P+   S P  S ++ E+  VITL     PSEP T  +   
Sbjct: 2543 TLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITL-----PSEPGTPTDSSA 2597

Query: 193  SEVVPN-PKGTPSPPCIVSTVPYHCVTPMASIQSGVAS---------LPQTTPTTTLAIA 242
            S+ + + P G+PS   +     +  V P+ +++  ++S         L   + T   A +
Sbjct: 2598 SQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPS 2657

Query: 243  SPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFP 302
            S Q   T+++  L +  +   +S     +P  ++ LS+ S+ +            PP+ P
Sbjct: 2658 SFQAAPTSVTQFLTTEVSKTEVSATRSTAP--SVGLSSISITI------------PPE-P 2702

Query: 303  ISLGS-HLAPLHQSSFGSVQLLG-----QTGPSALSDPTVKTISVDHSSTGAS------- 349
            ++L + HL        G +QL+G     +T P      T K I +  S+           
Sbjct: 2703 LALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITANE 2762

Query: 350  -YPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSL- 407
             Y  Q S + P      ++  +V +  +V P V     T++ +TC+ S S    T   + 
Sbjct: 2763 VYGKQISAVQP-----SIINLSVTS-SIVTP-VSLATETVTFVTCTASASYTTGTESLVG 2815

Query: 408  ---SPTTSLILKSSPNA--TYHYPLVAQMPVS--------SVGT----TPLVVTNPCTIA 450
               + TT L L +S +A   Y  P     P++        S+GT      L +T P T+ 
Sbjct: 2816 AEHAMTTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVP 2875

Query: 451  AAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTL 501
                T     + VS  ++ G + ++  T     V   V   E ++ V T +
Sbjct: 2876 PVGVTNGWTDSTVSQGITDGEVVDLSTTKSHRTV---VTMDESTSSVMTKI 2923



 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 97/395 (24%), Positives = 143/395 (36%), Gaps = 51/395 (12%)

Query: 1432 DLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK 1491
            D  P +V  + +K+  +T+    G      K    LP+ +P     P  P+    SSS  
Sbjct: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD 2400

Query: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551
             +   P P   P  P   P  P   P  P     P +P  T+L KK              
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPP-----PTSPKPTILPKK-------------- 2441

Query: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK 1611
             +TV SP  T          ATP     ++          G P  +     P    P P 
Sbjct: 2442 KLTVASPVTT----------ATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPS 2491

Query: 1612 EAPTPPAVT-PPSPEKGPATPAPKGTPTSPPVT--PSSLKDSPTSPASVTCKMGATVPQA 1668
              P+    T  P P K P  P P   P  P  T  P+ +   PT  +  +      V  A
Sbjct: 2492 SIPSGLVFTHRPEPSKPPIAPKPV-IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSA 2550

Query: 1669 SKGLPAKKGPTALKEVLVAP-----APESTPIITAPTRKGPQTKKSSA---TSPPICPDP 1720
               LP+   P +      +P       E+  +IT P+  G  T  S++   TS P+   P
Sbjct: 2551 DYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPL-GSP 2609

Query: 1721 SAKNGSKGPLSTVAP---APLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAA 1777
            S    S  P+ +V P   A  +P+  + +    G   + S   P+  P S  + P +   
Sbjct: 2610 SKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSAT-PVTAPSSFQAAPTSVTQ 2668

Query: 1778 F--EKVLPKPESASVSAAPS---PPVSLPLAPSPV 1807
            F   +V     SA+ S APS     +S+ + P P+
Sbjct: 2669 FLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPL 2703



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 83/343 (24%), Positives = 116/343 (33%), Gaps = 27/343 (7%)

Query: 813  GSAGPDTPIGNLSSPVSPVEAS---FLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA 869
            G   P + + + S  VS + A    F   +SL        P     P PP P   P P  
Sbjct: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL 2427

Query: 870  VTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKG 929
              P SPK   LP K+    S V    P     T    +  A+  ++  P     T AP  
Sbjct: 2428 PPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTL--ETTAVLRSNGLPVTRICTTAPPP 2485

Query: 930  IPASPSPKGAPTPPAAT-PPSPKGGPATPSPKWAPTP-----PAATPPSPKGGPATPS-- 981
            +P  P P   P+    T  P P   P  P P     P     P    P P G   T S  
Sbjct: 2486 VP--PKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMT 2543

Query: 982  -----PKGAPTPPAATPPSPKGGPATP--SPKGAPTPPAVTPPSPKGSPAATPFPKGAST 1034
                       P   +P SP    ++P  S     T   +T PS  G+P  +   +  ++
Sbjct: 2544 LNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITS 2603

Query: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATP-PSPKGG 1093
             P  +P   K   +  P+    P  P   +  P     T  + GA    +ATP  +P   
Sbjct: 2604 WPLGSP--SKDLVSVEPVFSVVP--PVTAVEIPISSEQTFYISGALQTFSATPVTAPSSF 2659

Query: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136
             A P+     +    +        +T P  G  +     PP P
Sbjct: 2660 QAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEP 2702



 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 93/361 (25%), Positives = 130/361 (36%), Gaps = 48/361 (13%)

Query: 1210 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAA 1269
            A+  P G+P+  ++ P  P+     P  + +    +A PP P   P  PPP   P PP  
Sbjct: 2373 ASQLPSGSPSV-SSLPAKPR-----PFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP 2426

Query: 1270 TPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS-------PPKGAP------TPPAAT 1316
             PP         P K     + VT  +P     T+          G P      T P   
Sbjct: 2427 LPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPV 2486

Query: 1317 PPSPKGSPGTPPPKGAPTPPAVTPPSPKGT-PTLPATTPSSKGGPTTPSSKEGPTPPAAT 1375
            PP P   P        P  P+  P +PK   P LP TT      PT    K  PT  + T
Sbjct: 2487 PPKPSSIPSGLVFTHRP-EPSKPPIAPKPVIPQLPTTTQK----PTDIHPK--PTGLSLT 2539

Query: 1376 PSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTP 1435
             S      +T    K    +PSP   P SP     SP+ + +   T      PS+    P
Sbjct: 2540 SSMTLN-LVTSADYK----LPSPT-SPLSPHSNKSSPRFSKSLTETYVVITLPSE----P 2589

Query: 1436 PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPA 1495
               T  S  +A  TS P G P+      +P    V P +  E P   +     S      
Sbjct: 2590 GTPTDSSASQA-ITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTF 2648

Query: 1496 TPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTV 1555
            +  P+ AP+     P+S  +   T  S+ +  A  +T          AP   L   ++T+
Sbjct: 2649 SATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRST----------APSVGLSSISITI 2698

Query: 1556 P 1556
            P
Sbjct: 2699 P 2699



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 96/375 (25%), Positives = 138/375 (36%), Gaps = 68/375 (18%)

Query: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPAT-----PSSKEASSPPAVTP 1587
            L +++T ++L+      PP+  +  P K     T   +  T     P+S+  S  P+V+ 
Sbjct: 2326 LEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSS 2385

Query: 1588 STYKGAPSPKELLI----------PPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637
               K  P  +   +          PP    P P   P PP + PP+  K    P  K T 
Sbjct: 2386 LPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTV 2445

Query: 1638 TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697
             SP  T + L D+ T+       +  T    S GLP  +  T      V P P S P   
Sbjct: 2446 ASPVTTATPLFDAVTT-------LETTAVLRSNGLPVTRICTTAPPP-VPPKPSSIPSGL 2497

Query: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTA-------- 1749
              T +   +K      PPI P P      + P +T  P  + P     S T+        
Sbjct: 2498 VFTHRPEPSK------PPIAPKPVI---PQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVT 2548

Query: 1750 KGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPT 1809
                   SP  PL+P  +K+S       F K L   E+  V   PS P          PT
Sbjct: 2549 SADYKLPSPTSPLSPHSNKSS-----PRFSKSL--TETYVVITLPSEP--------GTPT 2593

Query: 1810 LPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPE-----PISGGVPFQSVLVNMPT 1864
                 Q + S P   L SPSK L     + +  ++PP      PIS     Q+  ++   
Sbjct: 2594 DSSASQAITSWP---LGSPSKDLVSV--EPVFSVVPPVTAVEIPISSE---QTFYISGAL 2645

Query: 1865 PKSAGIPVPTPSAKQ 1879
               +  PV  PS+ Q
Sbjct: 2646 QTFSATPVTAPSSFQ 2660



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 87/369 (23%), Positives = 125/369 (33%), Gaps = 51/369 (13%)

Query: 691  KEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKK 750
            +E   + LP    +  + P  P P    + L      P  P   P P  PP   PP    
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP-- 2426

Query: 751  VDGISHTSALAPVASSPKECPTEDSGASAT-ASSKGTLTYLADSPSPLGVSVSPQTKRPP 809
                       P  +SPK  PT       T AS   T T L D+ + L  +         
Sbjct: 2427 ----------LPPPTSPK--PTILPKKKLTVASPVTTATPLFDAVTTLETTA-------- 2466

Query: 810  TKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA 869
              + +  P T I   + P  P + S +P + L F         TH P P  P  AP P  
Sbjct: 2467 VLRSNGLPVTRICTTAPPPVPPKPSSIP-SGLVF---------THRPEPSKPPIAPKP-- 2514

Query: 870  VTPLSPKGVTLPPKETPTPSVVNLP-------FPKEGPATPAPKQAPALSMTSSSPKKAR 922
            V P  P     P    P P+ ++L                P+P    +     SSP+ ++
Sbjct: 2515 VIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSK 2574

Query: 923  ATPAPKGIPASPSPKGAPTPPAATPPS---PKGGPA----TPSPKWAPTPPAATPPSPKG 975
            +      +   PS  G PT  +A+      P G P+    +  P ++  PP      P  
Sbjct: 2575 SLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPIS 2634

Query: 976  GPATPSPKGAPTPPAATP-PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAST 1034
               T    GA    +ATP  +P    A P+         V+      + +  P   G S+
Sbjct: 2635 SEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAP-SVGLSS 2693

Query: 1035 PPAATPPSP 1043
                 PP P
Sbjct: 2694 ISITIPPEP 2702



 Score = 40.8 bits (94), Expect = 0.014
 Identities = 62/257 (24%), Positives = 96/257 (37%), Gaps = 35/257 (13%)

Query: 1387 PSPKRGPAIPSPKGDPTSPA--VIPLSPKKAPATPVTRE-GAATPSKGDLTPPAV---TP 1440
            P+  R  A     GD  + A    PLS   + A     E    T   G +  P++     
Sbjct: 3485 PTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVD 3544

Query: 1441 VSLKKAPATSAP----KGGPATPSSKGDPT------LPAVTPPSPKEPPAPKQVATSSSP 1490
              ++     SAP    KGG     ++ D        L A +PP  K+ P P ++  SS  
Sbjct: 3545 AKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHL 3604

Query: 1491 KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP 1550
            +           P  P V+ S     P +P S    +        K  P  ++P++ L P
Sbjct: 3605 RADSTVQLAPSPPKSPKVLYS-----PISPLSPGKALESAFVPYEKPLPDDISPQKVLHP 3659

Query: 1551 PAMTVP--SPKKTP----AIPTPKEAPATPSSKEASSPPAVTPSTY--KGA----PSPKE 1598
                VP  SPK       ++  PK  P +P++ E+S  P      Y  KG+     S  +
Sbjct: 3660 DMAKVPPASPKTAKMMQRSMSDPK--PLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQ 3717

Query: 1599 LLIPPAVTSPSPKEAPT 1615
              +   + +P P+E  T
Sbjct: 3718 KKVKRTLPNPPPEEIST 3734



 Score = 38.1 bits (87), Expect = 0.090
 Identities = 52/223 (23%), Positives = 82/223 (36%), Gaps = 30/223 (13%)

Query: 1660 KMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPI--ITAPTRKGPQTKKSSATSPPIC 1717
            K G ++ +A K  P  K  +   + +   + ++ P+  I  P+ +     K         
Sbjct: 3496 KYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISA 3555

Query: 1718 PDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAA 1777
            P+ + K GS G             + DS   +    ++ SP     P + K  TPL    
Sbjct: 3556 PEKTYKGGSLG----------CQTEADSDTQSPQYLSATSP-----PKDKKRPTPLEIGY 3600

Query: 1778 FEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADE 1837
               +      ++V  APSPP S  +  SP+          P SPG  LES   P      
Sbjct: 3601 SSHLRA---DSTVQLAPSPPKSPKVLYSPIS---------PLSPGKALESAFVPYEKPLP 3648

Query: 1838 DELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVP-TPSAKQ 1879
            D++ P     P    VP  S        +S   P P +P+A +
Sbjct: 3649 DDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADE 3691



 Score = 32.0 bits (71), Expect = 6.5
 Identities = 42/168 (25%), Positives = 60/168 (35%), Gaps = 18/168 (10%)

Query: 1540 ATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL 1599
            AT  PK+   P  + +       A  T + AP+ P S +    P ++P       SP + 
Sbjct: 3583 ATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSP-ISPL------SPGKA 3635

Query: 1600 LIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKD----SPTSPA 1655
            L    V    P E P P  ++P           P  +P +  +   S+ D    SPT+  
Sbjct: 3636 LESAFV----PYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADE 3691

Query: 1656 SVTCKMGATVPQASKGLPAKKGPTALKEV---LVAPAPESTPIITAPT 1700
            S       T    +KG        A K+V   L  P PE     T  T
Sbjct: 3692 SSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEISTGTQST 3739


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score =  221 bits (562), Expect = 8e-57
 Identities = 360/1445 (24%), Positives = 513/1445 (35%), Gaps = 251/1445 (17%)

Query: 754  ISHTSALAPVASSPKECPT----EDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPP 809
            +S  +AL+ V+S   +        DS AS   ++K       +   P G+   P  ++PP
Sbjct: 157  LSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPP 216

Query: 810  T---KKGSAGPD------TPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS 860
                K+   G D      TP  ++SS       S  P      QG   +P T H+  P  
Sbjct: 217  KPIPKQQGPGRDPLQQDGTP-KSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQ 275

Query: 861  PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK 920
             + A  P        +G ++ P   P+PS    P  +  P  P P Q P    +   P K
Sbjct: 276  -RDASRPQTKQADIVRGESVKPS-LPSPS--KPPIQQPTPGKP-PAQQPGHEKSQPGPAK 330

Query: 921  ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATP 980
              A P+    P +  P G   PP   PP     PA   P     PPA    S K     P
Sbjct: 331  PPAQPSGLTKPLAQQP-GTVKPPVQ-PPGTTKPPA--QPLGPAKPPAQQTGSEKPSSEQP 386

Query: 981  SPKGAPTPPAA-TPPSPKGGPATPSPK--GAPTPPAVTP--PSPKGSPAATPFPKGASTP 1035
             PK    PP     P+ + GPA P  +  G P P A  P   SP  +P  T  P     P
Sbjct: 387  GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP--VQQP 444

Query: 1036 PAATPPSPKGSPAATPLPKGAPTTPAATLPSP------KGGPATPSLK--GAPTPPAATP 1087
                 P+ +  P  T   +  PT P + LP P      + GPA P  +  G+  PP+  P
Sbjct: 445  GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP 504

Query: 1088 PSPKGGPATPSP-KGAPMPPAAT-PPSPKGGLATP----PHKGAPTTPAATPPSPKGGLA 1141
             S K  P  P P K +P  P +T PPS + G A P    P    P+   +T P  + G  
Sbjct: 505  GSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG-- 562

Query: 1142 TPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT-TPAA 1200
                 G P  P    PS K     PP +G P T      + +  L  P      T T   
Sbjct: 563  ----SGKPLQPPTVSPSAK----QPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQ 614

Query: 1201 TPPSPKGGLATPSPK------------------GAPTTPAATPPSPKGGLATPSPKGAP- 1241
            T      G   P+P                   G    P  + P PK        K AP 
Sbjct: 615  TTVCSLCGF-NPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK-------LKTAPV 666

Query: 1242 -TTPAATPPSPKGGPATPPPKGAP------TPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294
             TT A +  SP+    +P    AP       P    PP L   +  P   G+P+     P
Sbjct: 667  TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPL---VKQPTLHGSPSAKAKQP 723

Query: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA-PTPPAVTPPSPKGTPTLPATT 1353
            P        +PPK  P+ P+    +P        PK   PT   V+  S    P +P++ 
Sbjct: 724  PEADSLSKPAPPK-EPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSK 782

Query: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGP----AIPSPKGDPTSPAVIP 1409
              S+       ++E  TPP  T S K   +  P   K  P    AIP P  D        
Sbjct: 783  VQSQ-------AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD-------- 827

Query: 1410 LSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGP---ATPSSKGDPT 1466
                   +  ++  G ++ SKG      V PV  K+ P  +  K  P   A P  KG PT
Sbjct: 828  -------SKIISHPGPSSESKGQ---KQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPT 877

Query: 1467 LPAVTP------PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP------------AV 1508
             P   P      P+P++ P P++ +   S      T AP   PT P            A 
Sbjct: 878  PPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGAS 937

Query: 1509 IPSSPKEVPAT-----PSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT---VPSPKK 1560
            I S    + +T     P S+  P AP      K+ PA   P  +  PP  T    P+P K
Sbjct: 938  IFSQASNLISTAGQPGPHSQSGPGAP-----MKQAPAPSQPPTSQGPPKSTGQAPPAPAK 992

Query: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620
              +IP  KE  A  + K    P A    T K   + K+   PP +       A    AV 
Sbjct: 993  --SIPVKKETKAPAAEK--LEPKAEQAPTVKRTETEKK---PPPIKDSKSLTAEPQKAVL 1045

Query: 1621 PPSPEKGPATPAPKGT-PTSPPVTPSSLKDSPTSPASVTCK------------------- 1660
            P   EK   +P P+ T P          KD P       CK                   
Sbjct: 1046 PTKLEK---SPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQ 1102

Query: 1661 ----MGATVPQASKGL--PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSP 1714
                +     +A  G     +K P A      +P P  T   +  T   PQ K       
Sbjct: 1103 EWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQ 1162

Query: 1715 PICPDPS----AKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAS 1770
             +  +       K      +  + P      +++ SK  K K ++   K PL  PE K  
Sbjct: 1163 EVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPL--PEEKKL 1220

Query: 1771 TPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSK 1830
             P      EK+  + +   +      P    L P    + P +Q+              K
Sbjct: 1221 IP----EEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQK----------HDLLK 1266

Query: 1831 PLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGT 1890
                  E++L   + P+ +  G          P  K  G+P  TP +             
Sbjct: 1267 SQVQIAEEKLEGRVAPKTVQEG--------KQPQTKMEGLPSGTPQS------------L 1306

Query: 1891 ESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEK-KARKAMSKLGL- 1948
              + D++   ++EQ     T +  Q+    E  E+   K+  S S++ K+ + +S  G  
Sbjct: 1307 PKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYS 1366

Query: 1949 -----RQVTGVTRVTIRKSKNILFVITKPDVYK--SPASDTYIVFGEAKI-EDLSQQAQL 2000
                   +  +  +     K+IL  + K    +  SP+S + +   E+ +   L  QA  
Sbjct: 1367 SDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQAST 1426

Query: 2001 AAAEKF--KVQGEAVS----NIQENTQ--TPTVQEESEEEEVDETGVEVKDIELVMSQAN 2052
             A EK   K Q   VS      QE TQ  + T++    EEE+ E+  E KD     SQ +
Sbjct: 1427 LADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQD 1486

Query: 2053 VSRAK 2057
            +  +K
Sbjct: 1487 IPSSK 1491



 Score =  176 bits (446), Expect = 2e-43
 Identities = 328/1410 (23%), Positives = 471/1410 (33%), Gaps = 240/1410 (17%)

Query: 543  PFSPAQAGLTTKKDPTVLPLVQAAPKNSPS---FQSTSSSPEIPLSPEATLAKKSLGEPL 599
            P  PAQ GL+  +        Q  P  SPS    + + S  ++    ++++    L E  
Sbjct: 102  PGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVN 161

Query: 600  PIGKPASSMTS----PLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFP---LES 652
             +   +S +       L  +S AS  +T                +I P +   P   +  
Sbjct: 162  ALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPK 221

Query: 653  ADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAP-KNHPVKEGTLTTLPLVPTASENCPVA 711
                G  P    GT    ++  P  E   S  P    P++  T T      T     P+ 
Sbjct: 222  QQGPGRDPLQQDGTPKSISSQQP--EKIKSQPPGTGKPIQGPTQTP----QTDHAKLPLQ 275

Query: 712  PSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECP 771
                      A +V    +  S+PSPS PP   P   K            P A  P    
Sbjct: 276  RDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK------------PPAQQPGHEK 323

Query: 772  TEDSGASATASSKGTLTYLADSPSPLGVSVSPQ-TKRPPTKKGSAGPDTPIGNLSSPVSP 830
            ++   A   A   G    LA  P  +   V P  T +PP +    GP  P    +    P
Sbjct: 324  SQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQP--LGPAKPPAQQTGSEKP 381

Query: 831  VEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAV-------TPLSPKGVTLPPK 883
                  P+      G   +PA    P  P  +   TP  +       +P    G T  P 
Sbjct: 382  SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441

Query: 884  ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP 943
            + P P    +P  + GP   + +Q       S  P  A+  P   G PA P P+    P 
Sbjct: 442  QQPGPG--KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPG-PAKPPPQ---QPG 495

Query: 944  AATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP 1003
            +A PPS + G   P P+  P P   +P  P G    PS +     P+A  PS    PA P
Sbjct: 496  SAKPPSQQPGSTKPPPQ-QPGPAKPSPQQP-GSTKPPSQQPGSAKPSAQQPS----PAKP 549

Query: 1004 SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAAT 1063
            S + +  P + T     G P   P     +  P+A  P  +G P  T  P    T     
Sbjct: 550  SAQQSTKPVSQT---GSGKPLQPP-----TVSPSAKQPPSQGLP-KTICPLCNTTELLLH 600

Query: 1064 LPSPKGGPATPSLKGAPTPPAATPPSPKGGPA---------TPSPKGAPMPPAATPPSPK 1114
            +P           +          P+P                   G  + P  + P PK
Sbjct: 601  VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK 660

Query: 1115 GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPP------ 1168
              L T P     TT A +  SP+    +P    AP    +  P PK     PPP      
Sbjct: 661  --LKTAP---VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPK----KPPPLVKQPT 711

Query: 1169 -KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA-PTTPAATPP 1226
              G+P+  A  PP     L+ P+P   P+ P+    +P        PK   PTT   +  
Sbjct: 712  LHGSPSAKAKQPPE-ADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSS 770

Query: 1227 SPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGA 1286
            S       PS K        T P  K   A P     PT    +P   K   A P  + A
Sbjct: 771  SATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSK---AIP--RPA 825

Query: 1287 PNPAVVTPPSP----KGGPATSPPKGAPTP-PAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341
             +  +++ P P    KG     P +    P  A T  SPK     P PKG+PTPP   P 
Sbjct: 826  SDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPK-PDAKPMPKGSPTPPGPRPT 884

Query: 1342 SPKGTPTLPATTP---------SSKGGPTTPSSKEGPTPPAATPSHK---GGPAMTPPSP 1389
            + +  PT P  +P         S   G  T + K  PT P  T + K    G ++   + 
Sbjct: 885  AGQTVPT-PQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQAS 943

Query: 1390 KRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT 1449
                    P     S    P+    AP+ P T +G    S G   P     + +KK   T
Sbjct: 944  NLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQG-PPKSTGQAPPAPAKSIPVKK--ET 1000

Query: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509
             AP      P ++  PT+   T    K PP     + ++ P+KA           LP  +
Sbjct: 1001 KAPAAEKLEPKAEQAPTVKR-TETEKKPPPIKDSKSLTAEPQKA----------VLPTKL 1049

Query: 1510 PSSPKEVPATPSSR-------RDP------------------IAPTATL--------LSK 1536
              SPK     P  +       +DP                    PT  L        L+ 
Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNC 1109

Query: 1537 KTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV----------- 1585
            +T   ++ +   I      PS  K   +P P E+    SS++ + PP V           
Sbjct: 1110 QTQRAISGQLGDIRKMPPAPSGPKASPMPVPTES----SSQKTAVPPQVKLVKKQEQEVK 1165

Query: 1586 TPSTYKGAPSPKELL----IPPAVTS---------------------PSPKEAP-TPPAV 1619
            T +        KE L    IPP VT+                     P P+E    P   
Sbjct: 1166 TEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEE 1225

Query: 1620 TPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ-------ASKGL 1672
               S EK P     K TP    + P +   +P        K    + +       A K +
Sbjct: 1226 KIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTV 1285

Query: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLST 1732
               K P    E L +  P+S P            K+   T+  I   P        P  T
Sbjct: 1286 QEGKQPQTKMEGLPSGTPQSLP------------KEDDKTTKTIKEQPQ-------PPCT 1326

Query: 1733 VAPAPLLPVQKDSSKTAKGKDASHS--PKGPLAPPESKASTPLTAAAFEKV---LP---- 1783
              P  + P ++ + K     D S S  PK P    ++  S+   +++  ++   +P    
Sbjct: 1327 AKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEK 1386

Query: 1784 ------KPESASVSAAPSPPVSLPLAPSPV 1807
                  K +S S  ++PS P  L    S V
Sbjct: 1387 DILKGLKKDSFSQESSPSSPSDLAKLESTV 1416



 Score =  146 bits (369), Expect = 2e-34
 Identities = 307/1322 (23%), Positives = 424/1322 (32%), Gaps = 207/1322 (15%)

Query: 561  PLVQAAPKNSPSFQSTSSSP----EIPLSPEATLAKKSLGEPLPIGKPASSMTS------ 610
            PL Q  PK  P  Q     P      P S  +   +K   +P   GKP    T       
Sbjct: 210  PLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269

Query: 611  ---PLGVNSSASVIKTDSYAGPDSAGPLL----KSSLITPTVAAFPLESADPAGVAPTTA 663
               PL  ++S    K       +S  P L    K  +  PT    P +        P  A
Sbjct: 270  AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329

Query: 664  KGTSTYTTTASPFLEGTVSLAPKNHP---VKEGTLTTLPLVPTASENCPVAPSPQNTCAP 720
            K  +  +    P  +   ++ P   P    K       P  P A +     PS +    P
Sbjct: 330  KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP-GP 388

Query: 721  LATLVLAPEI---PKSVPSPSLPPA---GTPPGTKKVDGI-SHTSALAPVAS-----SPK 768
             A L   P +   P   P P+ PP    GTP    +  G+ S   A  P  +      P 
Sbjct: 389  KA-LAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG 447

Query: 769  ECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQ------TKRPPTKKGSAGPDT--P 820
            + P + +G   T++ +   T     PS L     P        K PP + GSA P +  P
Sbjct: 448  KIPAQQAGPGKTSAQQ---TGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP 504

Query: 821  IGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH-SPTPPSPKGAPTPSAVTPLSPKGVT 879
                  P  P  A   P+   S +     P +   S   PSP       +  P+S  G +
Sbjct: 505  GSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG-S 563

Query: 880  LPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSS----PKKAR-------ATPAPK 928
              P + PT S    P  K+ P+   PK    L  T+      P+KA         T    
Sbjct: 564  GKPLQPPTVS----PSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCS 619

Query: 929  GIPASPSPK------------------GAPTPPAATPPSPK--GGPATPSPKWAPTPPAA 968
                +P+P                   G    P  + P PK    P T       T  A 
Sbjct: 620  LCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVT-------TTSAV 672

Query: 969  TPPSPKGGPATPSPKGAPTPPAATPPSPKGGP---ATPSPKGAPTPPAVTPPSPKGSPAA 1025
            +  SP+    +P    AP    +  P PK  P     P+  G+P+  A  PP       A
Sbjct: 673  SKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE------A 726

Query: 1026 TPFPKGASTPPAATPPSPKGSPAATPLPKG----APTTPAATLPSPKGGPATPSLKGAPT 1081
                K A     + P     +P A   PK      PTT   +  S    P  PS K    
Sbjct: 727  DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQ 786

Query: 1082 PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP-PHKGAPTTPAATPPSPKGG- 1139
                T P  K   A PS      PP     SP    A P P   +       P S   G 
Sbjct: 787  AEEKTTPPLKTDSAKPSQS---FPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQ 843

Query: 1140 -LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198
                P  K      A T  SPK   A P PKG+PT P    P P  G   P+P+ +P   
Sbjct: 844  KQVDPVQKKEEPKKAQTKMSPKPD-AKPMPKGSPTPPG---PRPTAGQTVPTPQQSPKPQ 899

Query: 1199 AATPP-SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPAT 1257
              +   S   G  T +PK  PTTP  T      G    S     +   +T   P  GP +
Sbjct: 900  EQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA-SIFSQASNLISTAGQP--GPHS 956

Query: 1258 PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP 1317
                GAP   A  P         P  +G P      PP+P     + P K     PAA  
Sbjct: 957  QSGPGAPMKQAPAPSQ------PPTSQGPPKSTGQAPPAP---AKSIPVKKETKAPAAEK 1007

Query: 1318 PSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPS 1377
              PK       P    T     PP  K + +L A  P     PT    ++ P P +  P 
Sbjct: 1008 LEPKAEQA---PTVKRTETEKKPPPIKDSKSLTA-EPQKAVLPT--KLEKSPKPESTCPL 1061

Query: 1378 HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP-----KKAPATPVTREGAATPSKGD 1432
             K    +    P         K    +      +P     ++        + A +   GD
Sbjct: 1062 CKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGD 1121

Query: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKK 1492
            +          K  PA S PK  P    ++      AV P         ++V T +    
Sbjct: 1122 IR---------KMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVI 1172

Query: 1493 APATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPA 1552
                   +    +P ++ +  K+  +     +      A+ L +K P  L  ++ LIP  
Sbjct: 1173 LEKVKETLSMEKIPPMVTTDQKQEESKLEKDK------ASALQEKKP--LPEEKKLIPEE 1224

Query: 1553 MTVPSPKKTPAI----PTPKEAPATPSSK-------------------EASSPPAVTPST 1589
              + S +K P +    PTP++    P +K                   E      V P T
Sbjct: 1225 EKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKT 1284

Query: 1590 ----------YKGAPS--PKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637
                       +G PS  P+ L      T+ + KE P PP    P        P  + T 
Sbjct: 1285 VQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPD----QVEPGKEKTE 1340

Query: 1638 TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697
                 + +S    P SP  +     +    +S G+ +  G            P   P   
Sbjct: 1341 KEDDKSDTSSSQQPKSPQGL-----SDTGYSSDGISSSLG----------EIPSLIPTDE 1385

Query: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757
                KG +    S  S P  P   AK  S       A A  L  +K   KT   + +   
Sbjct: 1386 KDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQ 1445

Query: 1758 PK 1759
            PK
Sbjct: 1446 PK 1447



 Score = 88.6 bits (218), Expect = 6e-17
 Identities = 204/939 (21%), Positives = 296/939 (31%), Gaps = 180/939 (19%)

Query: 13   EQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPST 72
            +++  +PQ + A +    ++  +     P P+ PP   P P + P          P P+ 
Sbjct: 275  QRDASRPQTKQADIVRGESVKPSL----PSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAK 330

Query: 73   IASTPLEVPFPQSSSGTALPLGTAP---EAPTFLPNLIGPPISPAALALASPMIAPTLKG 129
              + P         SG   PL   P   + P   P    PP  P  L  A P    T   
Sbjct: 331  PPAQP---------SGLTKPLAQQPGTVKPPVQPPGTTKPPAQP--LGPAKPPAQQTGSE 379

Query: 130  TPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLN 189
             PSS  P                  P  L  PP V         T +    P++P T   
Sbjct: 380  KPSSEQP-----------------GPKALAQPPGVGK-------TPAQQPGPAKPPTQQV 415

Query: 190  KVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDT 249
              P  +   P G  SP    +  P    TP+     G     Q  P  T           
Sbjct: 416  GTPKPLAQQP-GLQSP----AKAPGPTKTPVQQPGPGKIPAQQAGPGKT----------- 459

Query: 250  TISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHL 309
              S+    P  P S  L GP  PP                 +  GP  PP  P   GS  
Sbjct: 460  --SAQQTGPTKPPS-QLPGPAKPP----------------PQQPGPAKPP--PQQPGSAK 498

Query: 310  APLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPA 369
             P  Q    +     Q GP+  S     +        G++ PS +   P  PS      A
Sbjct: 499  PPSQQPG-STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS------A 551

Query: 370  TVAAFPVVAPSVDK--GPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPL 427
              +  PV      K   P T+S     P       T   L  TT L+L     A ++   
Sbjct: 552  QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611

Query: 428  VAQMPVSSV-GTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMA 486
              Q  V S+ G  P    NP        T  +   C++  M      ++ P      V +
Sbjct: 612  ECQTTVCSLCGFNP----NP------HLTEVKEWLCLNCQMKRALGGDLAP------VPS 655

Query: 487  PVAPKEPSTQVATTLRIPVSPPLPDPEDLKN--LPSSVLVKFPTQKDLQTVPASLEGAPF 544
               PK  +  V TT  +  S P P     K    P   L K P  K     P  L   P 
Sbjct: 656  SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK----PPPLVKQPT 711

Query: 545  SPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKP 604
                     K+ P    L + AP   PS  S           +A +A     +P  + KP
Sbjct: 712  LHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQD--------KAPVADDKPKQPKMV-KP 762

Query: 605  ASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAK 664
             + +     V+SS++  K      PD     ++S     T      +SA P+   P T +
Sbjct: 763  TTDL-----VSSSSATTK------PDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGE 811

Query: 665  GTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATL 724
              S + + A P             P  +  + + P   + S+        Q    P    
Sbjct: 812  KVSPFDSKAIP------------RPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQ 859

Query: 725  VLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSK 784
                  P + P P   P  TPPG +   G            +P++ P     +   + + 
Sbjct: 860  TKMSPKPDAKPMPKGSP--TPPGPRPTAG--------QTVPTPQQSPKPQEQSRRFSLNL 909

Query: 785  GTLTYLADSPSP---------------LGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVS 829
            G++T   D+P                  G S+  Q     +  G  GP +     S P +
Sbjct: 910  GSIT---DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ----SGPGA 962

Query: 830  PVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPS 889
            P++ +  P    + QG    P  +    PP+P     P      +P    L PK    P+
Sbjct: 963  PMKQAPAPSQPPTSQG----PPKSTGQAPPAP-AKSIPVKKETKAPAAEKLEPKAEQAPT 1017

Query: 890  VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPK 928
            V      K+ P     K   A    +  P K   +P P+
Sbjct: 1018 VKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE 1056



 Score = 78.2 bits (191), Expect = 8e-14
 Identities = 130/571 (22%), Positives = 189/571 (33%), Gaps = 86/571 (15%)

Query: 723  TLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVA---------SSPKECPTE 773
            +L+L    P S  + S+PP+ TP  T  V  +  T + +P+          + P +  T+
Sbjct: 2161 SLILTYSEP-SESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITK 2219

Query: 774  DSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEA 833
               +   +SS      + D P  + VS+     R     G A  D  + +LS   S +  
Sbjct: 2220 FEDSEEISSSTYFPGSIIDYPEEISVSLD----RTAPPDGRASADHIVISLSDMASSIIE 2275

Query: 834  SFL--PENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPL-------------SPKGV 878
            S +  PE  ++   S D   +   P   + K       +  L             +   +
Sbjct: 2276 SVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSL 2335

Query: 879  TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP-- 936
            +    + P  SV+ LP  KE  +T              + +    +P+   +PA P P  
Sbjct: 2336 SETVFDHPPSSVIALPM-KEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFF 2394

Query: 937  KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSP 996
            + +    +A PP P   P  P     P PP   PP P   P +P P           P  
Sbjct: 2395 RSSSLDISAQPPPPPPPPPPP-----PPPPPPPPPPPLPPPTSPKP--------TILPKK 2441

Query: 997  KGGPATPSPKGAPTPPAVTPPSPKG--SPAATPFPKGASTPPAATPPSPKGSPAA----- 1049
            K   A+P     P   AVT             P  +  +T P   PP P   P+      
Sbjct: 2442 KLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTH 2501

Query: 1050 TPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPS-------PKGA 1102
             P P   P  P          P  P L      P    P P G   T S           
Sbjct: 2502 RPEPSKPPIAPK---------PVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADY 2552

Query: 1103 PMPPAATPPSPKGGLATPPHKGA--PTTPAATPPSPKGGLATPPPKGAPTTPAATP-PSP 1159
             +P   +P SP    ++P    +   T    T PS  G   TP    A     + P  SP
Sbjct: 2553 KLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPG---TPTDSSASQAITSWPLGSP 2609

Query: 1160 KGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1219
               L +  P  +   P      P     T    GA  T +ATP +            AP+
Sbjct: 2610 SKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVT------------APS 2657

Query: 1220 TPAATPPSPKGGLATPSPKGAPTTPAATPPS 1250
            +  A P S    L T   K   +   +T PS
Sbjct: 2658 SFQAAPTSVTQFLTTEVSKTEVSATRSTAPS 2688



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 235/1064 (22%), Positives = 344/1064 (32%), Gaps = 196/1064 (18%)

Query: 17   PQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPL-------SAANQASPFPS 69
            P  Q      P++    + +    PGPT  P   P P + P        ++A Q  P   
Sbjct: 410  PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469

Query: 70   PSTIASTPLEVPFPQSSSGTALPLGTAP---EAPTFLPNLIGPPISPAALALASPMIAPT 126
            PS +   P     P    G A P    P   + P+  P    PP      A  SP    +
Sbjct: 470  PSQL---PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526

Query: 127  LKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKT 186
             K  P S  P      A  S Q+ S   P+   S   V+   SG       P+ P     
Sbjct: 527  TK--PPSQQP----GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK------PLQPPTVSP 574

Query: 187  NLNKVPSEVVPNPKGTPSPPCIVSTVPYH------------CVTPMASIQSGVASLPQTT 234
            +  + PS+ +P    T  P C  + +  H            C T + S+  G    P  T
Sbjct: 575  SAKQPPSQGLPK---TICPLCNTTELLLHVPEKANFNTCTECQTTVCSL-CGFNPNPHLT 630

Query: 235  PTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAG 294
                    + Q+K      +   P +P       PV+  +A+S S+   P  TS +K A 
Sbjct: 631  EVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQ-PQQTSPKKDAA 689

Query: 295  PNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVK--TISVDHSSTGASYPS 352
            P                         Q L +        P VK  T+    S+     P 
Sbjct: 690  PK------------------------QDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE 725

Query: 353  QRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTS 412
              S+  P P +   VP+     P VA    K P  +                    PTT 
Sbjct: 726  ADSLSKPAPPKEPSVPSEQDKAP-VADDKPKQPKMV-------------------KPTTD 765

Query: 413  LILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPI 472
            L+  SS       P       +   TTP + T+    +A P+ +F        P  S  I
Sbjct: 766  LVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTD----SAKPSQSFPPTGEKVSPFDSKAI 821

Query: 473  SNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDL 532
                P S + ++  P    E   Q              DP   K  P     K   + D 
Sbjct: 822  P--RPASDSKIISHPGPSSESKGQKQV-----------DPVQKKEEPKKAQTKMSPKPDA 868

Query: 533  QTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQS----------TSSSPEI 582
            + +P      P     AG T       +P  Q +PK  P  QS          T +    
Sbjct: 869  KPMPKGSPTPPGPRPTAGQT-------VPTPQQSPK--PQEQSRRFSLNLGSITDAPKSQ 919

Query: 583  PLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLIT 642
            P +P+ T+  K  G    I   AS++ S  G           S +GP    P+ ++   +
Sbjct: 920  PTTPQETVTGKLFGFGASIFSQASNLISTAGQPG------PHSQSGP--GAPMKQAPAPS 971

Query: 643  -PTVAAFPLESADPAGVAPTTAKGTSTYTTTASPF---LEGTVSLAP---------KNHP 689
             P  +  P +S   A  AP  AK       T +P    LE     AP         K  P
Sbjct: 972  QPPTSQGPPKSTGQAPPAP--AKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPP 1029

Query: 690  VKEG-TLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGT 748
            +K+  +LT  P           +P P++TC PL    L      ++ S   P   T    
Sbjct: 1030 IKDSKSLTAEPQKAVLPTKLEKSPKPESTC-PLCKTEL------NIGSKDPPNFNTCTEC 1082

Query: 749  K----KVDGISHTSALAPVAS-SPKECPTEDSGASATASSKGTLTYLADSP-----SPLG 798
            K     + G + T  L  +       C T+     A +   G +  +  +P     SP+ 
Sbjct: 1083 KNQVCNLCGFNPTPHLTEIQEWLCLNCQTQ----RAISGQLGDIRKMPPAPSGPKASPMP 1138

Query: 799  V---SVSPQTKRPP----TKKGSAGPDTPIGNL----------SSPVSPVEASFLPENSL 841
            V   S S +T  PP     KK      T    +             + P+  +   +   
Sbjct: 1139 VPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEES 1198

Query: 842  SFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPA 901
              +  K S      P P   K  P    +   S +   L  ++ PTP    L  P+   +
Sbjct: 1199 KLEKDKASALQEKKPLPEEKKLIPEEEKIR--SEEKKPLLEEKKPTPEDKKL-LPEAKTS 1255

Query: 902  TPAPKQAPAL-SMTSSSPKKARATPAPKGIPASPSPKGAPTP-PAATPPS-PK-GGPATP 957
             P  ++   L S    + +K     APK +     P+      P+ TP S PK     T 
Sbjct: 1256 APEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTK 1315

Query: 958  SPKWAPTPPAATPP---SPKGGPATPSPKGAPTPPAATPPSPKG 998
            + K  P PP    P    P           + T  +  P SP+G
Sbjct: 1316 TIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQG 1359



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 124/510 (24%), Positives = 182/510 (35%), Gaps = 90/510 (17%)

Query: 1472 PPSPKEPPAP--KQVATSSSPKKAPATPAPMGAPTLPAVIPS-------SPKEVPA-TPS 1521
            PP+  E P+   KQ   SS P K    P   G P  P +  S       S +++P  +PS
Sbjct: 72   PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPS 131

Query: 1522 SRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASS 1581
            +     + + T L ++  +++ P       A++  S       P    + +  S +E + 
Sbjct: 132  TISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTK 191

Query: 1582 PPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAP--------------TPPAVTPPSPEKG 1627
               V     K    P+ ++ PP    P PK  P              TP +++   PEK 
Sbjct: 192  KQKV---VQKEQGKPEGIIKPPLQQQP-PKPIPKQQGPGRDPLQQDGTPKSISSQQPEKI 247

Query: 1628 PATPAPKGTPTSPPV-TPSSLKDSPTSPASVTCKMGATVPQAS-----KGLPAKKG-PTA 1680
             + P   G P   P  TP       T  A +  +  A+ PQ       +G   K   P+ 
Sbjct: 248  KSQPPGTGKPIQGPTQTPQ------TDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP 301

Query: 1681 LKEVLVAPAPESTPI------ITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVA 1734
             K  +  P P   P        + P    P  + S  T P      + K   + P +T  
Sbjct: 302  SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKP 361

Query: 1735 PA-PLLPVQKDSSKTAKGKDASHSP------------------KGPLAPPESKASTPLTA 1775
            PA PL P +  + +T   K +S  P                   GP  PP  +  TP   
Sbjct: 362  PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTP--- 418

Query: 1776 AAFEKVLPKPESASVSAAPSP---PVSLPLAPSPVPTL---PPK---QQFLPSSPGLVLE 1826
               + +  +P   S + AP P   PV  P  P  +P     P K   QQ  P+ P   L 
Sbjct: 419  ---KPLAQQPGLQSPAKAPGPTKTPVQQP-GPGKIPAQQAGPGKTSAQQTGPTKPPSQLP 474

Query: 1827 SPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTP----SAKQPVT 1882
             P+KP  P  +       P +P S   P Q      P P+  G   P+P    S K P  
Sbjct: 475  GPAKP--PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP-- 530

Query: 1883 KNNKGSGTESDSDESVPELEEQDSTQATTQ 1912
                GS   S    S  +   Q ST+  +Q
Sbjct: 531  SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560



 Score = 73.2 bits (178), Expect = 3e-12
 Identities = 81/315 (25%), Positives = 123/315 (39%), Gaps = 43/315 (13%)

Query: 1297 PKGGPATSPPKGAPTP--------PAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPT 1348
            P G P+ S     P P         +A PP P   P  PPP   P PP   PP P  T  
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP---PPLPPPTSP 2433

Query: 1349 LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI 1408
             P   P  K    +P +        ATP       +   +  R   +P  +   T+P  +
Sbjct: 2434 KPTILPKKKLTVASPVT-------TATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPV 2486

Query: 1409 PLSPKKAPATPVTREGAATPSKGDLTPPAVTP--VSLKKAPATSAPKGGPATPSSKGDPT 1466
            P  P   P+  V       PSK  + P  V P   +  + P    PK  P   S     T
Sbjct: 2487 PPKPSSIPSGLVFTH-RPEPSKPPIAPKPVIPQLPTTTQKPTDIHPK--PTGLSLTSSMT 2543

Query: 1467 LPAVTP-----PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPS 1521
            L  VT      PSP  P +P   +  SSP+ + +        TLP+  P +P +  A+ +
Sbjct: 2544 LNLVTSADYKLPSPTSPLSPH--SNKSSPRFSKSLTETYVVITLPSE-PGTPTDSSASQA 2600

Query: 1522 SRRDPI-APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEAS 1580
                P+ +P+  L+S      + P  +++PP   V  P     I + +    + + +  S
Sbjct: 2601 ITSWPLGSPSKDLVS------VEPVFSVVPPVTAVEIP-----ISSEQTFYISGALQTFS 2649

Query: 1581 SPPAVTPSTYKGAPS 1595
            + P   PS+++ AP+
Sbjct: 2650 ATPVTAPSSFQAAPT 2664



 Score = 73.2 bits (178), Expect = 3e-12
 Identities = 129/531 (24%), Positives = 209/531 (39%), Gaps = 100/531 (18%)

Query: 41   PGPTLPPPCSPAPQQCPLSAANQASPFPSPSTI--ASTPLEVPFPQSSSG---TALPLGT 95
            P P LPPP SP P   P      ASP  + + +  A T LE      S+G   T +    
Sbjct: 2423 PPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTA 2482

Query: 96   APEAP------------TFLPNLIGPPISPAALALASPM-------IAPTLKG-TPSSSA 135
             P  P            T  P    PPI+P  +    P        I P   G + +SS 
Sbjct: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSM 2542

Query: 136  PLALVALAPHSV-QKSSAFPPNLLTSPP--SVAVAESGSVITLSAPIAPSEPKTNLNKVP 192
             L LV  A + +   +S   P+   S P  S ++ E+  VITL     PSEP T  +   
Sbjct: 2543 TLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITL-----PSEPGTPTDSSA 2597

Query: 193  SEVVPN-PKGTPSPPCIVSTVPYHCVTPMASIQSGVAS---------LPQTTPTTTLAIA 242
            S+ + + P G+PS   +     +  V P+ +++  ++S         L   + T   A +
Sbjct: 2598 SQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPS 2657

Query: 243  SPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFP 302
            S Q   T+++  L +  +   +S     +P  ++ LS+ S+ +            PP+ P
Sbjct: 2658 SFQAAPTSVTQFLTTEVSKTEVSATRSTAP--SVGLSSISITI------------PPE-P 2702

Query: 303  ISLGS-HLAPLHQSSFGSVQLLG-----QTGPSALSDPTVKTISVDHSSTGAS------- 349
            ++L + HL        G +QL+G     +T P      T K I +  S+           
Sbjct: 2703 LALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITANE 2762

Query: 350  -YPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSL- 407
             Y  Q S + P      ++  +V +  +V P V     T++ +TC+ S S    T   + 
Sbjct: 2763 VYGKQISAVQP-----SIINLSVTS-SIVTP-VSLATETVTFVTCTASASYTTGTESLVG 2815

Query: 408  ---SPTTSLILKSSPNA--TYHYPLVAQMPVS--------SVGT----TPLVVTNPCTIA 450
               + TT L L +S +A   Y  P     P++        S+GT      L +T P T+ 
Sbjct: 2816 AEHAMTTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVP 2875

Query: 451  AAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTL 501
                T     + VS  ++ G + ++  T     V   V   E ++ V T +
Sbjct: 2876 PVGVTNGWTDSTVSQGITDGEVVDLSTTKSHRTV---VTMDESTSSVMTKI 2923



 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 97/395 (24%), Positives = 143/395 (36%), Gaps = 51/395 (12%)

Query: 1432 DLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK 1491
            D  P +V  + +K+  +T+    G      K    LP+ +P     P  P+    SSS  
Sbjct: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD 2400

Query: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551
             +   P P   P  P   P  P   P  P     P +P  T+L KK              
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPP-----PTSPKPTILPKK-------------- 2441

Query: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK 1611
             +TV SP  T          ATP     ++          G P  +     P    P P 
Sbjct: 2442 KLTVASPVTT----------ATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPS 2491

Query: 1612 EAPTPPAVT-PPSPEKGPATPAPKGTPTSPPVT--PSSLKDSPTSPASVTCKMGATVPQA 1668
              P+    T  P P K P  P P   P  P  T  P+ +   PT  +  +      V  A
Sbjct: 2492 SIPSGLVFTHRPEPSKPPIAPKPV-IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSA 2550

Query: 1669 SKGLPAKKGPTALKEVLVAP-----APESTPIITAPTRKGPQTKKSSA---TSPPICPDP 1720
               LP+   P +      +P       E+  +IT P+  G  T  S++   TS P+   P
Sbjct: 2551 DYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPL-GSP 2609

Query: 1721 SAKNGSKGPLSTVAP---APLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAA 1777
            S    S  P+ +V P   A  +P+  + +    G   + S   P+  P S  + P +   
Sbjct: 2610 SKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSAT-PVTAPSSFQAAPTSVTQ 2668

Query: 1778 F--EKVLPKPESASVSAAPS---PPVSLPLAPSPV 1807
            F   +V     SA+ S APS     +S+ + P P+
Sbjct: 2669 FLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPL 2703



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 83/343 (24%), Positives = 116/343 (33%), Gaps = 27/343 (7%)

Query: 813  GSAGPDTPIGNLSSPVSPVEAS---FLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA 869
            G   P + + + S  VS + A    F   +SL        P     P PP P   P P  
Sbjct: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL 2427

Query: 870  VTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKG 929
              P SPK   LP K+    S V    P     T    +  A+  ++  P     T AP  
Sbjct: 2428 PPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTL--ETTAVLRSNGLPVTRICTTAPPP 2485

Query: 930  IPASPSPKGAPTPPAAT-PPSPKGGPATPSPKWAPTP-----PAATPPSPKGGPATPS-- 981
            +P  P P   P+    T  P P   P  P P     P     P    P P G   T S  
Sbjct: 2486 VP--PKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMT 2543

Query: 982  -----PKGAPTPPAATPPSPKGGPATP--SPKGAPTPPAVTPPSPKGSPAATPFPKGAST 1034
                       P   +P SP    ++P  S     T   +T PS  G+P  +   +  ++
Sbjct: 2544 LNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITS 2603

Query: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATP-PSPKGG 1093
             P  +P   K   +  P+    P  P   +  P     T  + GA    +ATP  +P   
Sbjct: 2604 WPLGSP--SKDLVSVEPVFSVVP--PVTAVEIPISSEQTFYISGALQTFSATPVTAPSSF 2659

Query: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136
             A P+     +    +        +T P  G  +     PP P
Sbjct: 2660 QAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEP 2702



 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 93/361 (25%), Positives = 130/361 (36%), Gaps = 48/361 (13%)

Query: 1210 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAA 1269
            A+  P G+P+  ++ P  P+     P  + +    +A PP P   P  PPP   P PP  
Sbjct: 2373 ASQLPSGSPSV-SSLPAKPR-----PFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP 2426

Query: 1270 TPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS-------PPKGAP------TPPAAT 1316
             PP         P K     + VT  +P     T+          G P      T P   
Sbjct: 2427 LPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPV 2486

Query: 1317 PPSPKGSPGTPPPKGAPTPPAVTPPSPKGT-PTLPATTPSSKGGPTTPSSKEGPTPPAAT 1375
            PP P   P        P  P+  P +PK   P LP TT      PT    K  PT  + T
Sbjct: 2487 PPKPSSIPSGLVFTHRP-EPSKPPIAPKPVIPQLPTTTQK----PTDIHPK--PTGLSLT 2539

Query: 1376 PSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTP 1435
             S      +T    K    +PSP   P SP     SP+ + +   T      PS+    P
Sbjct: 2540 SSMTLN-LVTSADYK----LPSPT-SPLSPHSNKSSPRFSKSLTETYVVITLPSE----P 2589

Query: 1436 PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPA 1495
               T  S  +A  TS P G P+      +P    V P +  E P   +     S      
Sbjct: 2590 GTPTDSSASQA-ITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTF 2648

Query: 1496 TPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTV 1555
            +  P+ AP+     P+S  +   T  S+ +  A  +T          AP   L   ++T+
Sbjct: 2649 SATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRST----------APSVGLSSISITI 2698

Query: 1556 P 1556
            P
Sbjct: 2699 P 2699



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 96/375 (25%), Positives = 138/375 (36%), Gaps = 68/375 (18%)

Query: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPAT-----PSSKEASSPPAVTP 1587
            L +++T ++L+      PP+  +  P K     T   +  T     P+S+  S  P+V+ 
Sbjct: 2326 LEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSS 2385

Query: 1588 STYKGAPSPKELLI----------PPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637
               K  P  +   +          PP    P P   P PP + PP+  K    P  K T 
Sbjct: 2386 LPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTV 2445

Query: 1638 TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697
             SP  T + L D+ T+       +  T    S GLP  +  T      V P P S P   
Sbjct: 2446 ASPVTTATPLFDAVTT-------LETTAVLRSNGLPVTRICTTAPPP-VPPKPSSIPSGL 2497

Query: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTA-------- 1749
              T +   +K      PPI P P      + P +T  P  + P     S T+        
Sbjct: 2498 VFTHRPEPSK------PPIAPKPVI---PQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVT 2548

Query: 1750 KGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPT 1809
                   SP  PL+P  +K+S       F K L   E+  V   PS P          PT
Sbjct: 2549 SADYKLPSPTSPLSPHSNKSS-----PRFSKSL--TETYVVITLPSEP--------GTPT 2593

Query: 1810 LPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPE-----PISGGVPFQSVLVNMPT 1864
                 Q + S P   L SPSK L     + +  ++PP      PIS     Q+  ++   
Sbjct: 2594 DSSASQAITSWP---LGSPSKDLVSV--EPVFSVVPPVTAVEIPISSE---QTFYISGAL 2645

Query: 1865 PKSAGIPVPTPSAKQ 1879
               +  PV  PS+ Q
Sbjct: 2646 QTFSATPVTAPSSFQ 2660



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 87/369 (23%), Positives = 125/369 (33%), Gaps = 51/369 (13%)

Query: 691  KEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKK 750
            +E   + LP    +  + P  P P    + L      P  P   P P  PP   PP    
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP-- 2426

Query: 751  VDGISHTSALAPVASSPKECPTEDSGASAT-ASSKGTLTYLADSPSPLGVSVSPQTKRPP 809
                       P  +SPK  PT       T AS   T T L D+ + L  +         
Sbjct: 2427 ----------LPPPTSPK--PTILPKKKLTVASPVTTATPLFDAVTTLETTA-------- 2466

Query: 810  TKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA 869
              + +  P T I   + P  P + S +P + L F         TH P P  P  AP P  
Sbjct: 2467 VLRSNGLPVTRICTTAPPPVPPKPSSIP-SGLVF---------THRPEPSKPPIAPKP-- 2514

Query: 870  VTPLSPKGVTLPPKETPTPSVVNLP-------FPKEGPATPAPKQAPALSMTSSSPKKAR 922
            V P  P     P    P P+ ++L                P+P    +     SSP+ ++
Sbjct: 2515 VIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSK 2574

Query: 923  ATPAPKGIPASPSPKGAPTPPAATPPS---PKGGPA----TPSPKWAPTPPAATPPSPKG 975
            +      +   PS  G PT  +A+      P G P+    +  P ++  PP      P  
Sbjct: 2575 SLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPIS 2634

Query: 976  GPATPSPKGAPTPPAATP-PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAST 1034
               T    GA    +ATP  +P    A P+         V+      + +  P   G S+
Sbjct: 2635 SEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAP-SVGLSS 2693

Query: 1035 PPAATPPSP 1043
                 PP P
Sbjct: 2694 ISITIPPEP 2702



 Score = 40.8 bits (94), Expect = 0.014
 Identities = 62/257 (24%), Positives = 96/257 (37%), Gaps = 35/257 (13%)

Query: 1387 PSPKRGPAIPSPKGDPTSPA--VIPLSPKKAPATPVTRE-GAATPSKGDLTPPAV---TP 1440
            P+  R  A     GD  + A    PLS   + A     E    T   G +  P++     
Sbjct: 3485 PTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVD 3544

Query: 1441 VSLKKAPATSAP----KGGPATPSSKGDPT------LPAVTPPSPKEPPAPKQVATSSSP 1490
              ++     SAP    KGG     ++ D        L A +PP  K+ P P ++  SS  
Sbjct: 3545 AKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHL 3604

Query: 1491 KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP 1550
            +           P  P V+ S     P +P S    +        K  P  ++P++ L P
Sbjct: 3605 RADSTVQLAPSPPKSPKVLYS-----PISPLSPGKALESAFVPYEKPLPDDISPQKVLHP 3659

Query: 1551 PAMTVP--SPKKTP----AIPTPKEAPATPSSKEASSPPAVTPSTY--KGA----PSPKE 1598
                VP  SPK       ++  PK  P +P++ E+S  P      Y  KG+     S  +
Sbjct: 3660 DMAKVPPASPKTAKMMQRSMSDPK--PLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQ 3717

Query: 1599 LLIPPAVTSPSPKEAPT 1615
              +   + +P P+E  T
Sbjct: 3718 KKVKRTLPNPPPEEIST 3734



 Score = 38.1 bits (87), Expect = 0.090
 Identities = 52/223 (23%), Positives = 82/223 (36%), Gaps = 30/223 (13%)

Query: 1660 KMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPI--ITAPTRKGPQTKKSSATSPPIC 1717
            K G ++ +A K  P  K  +   + +   + ++ P+  I  P+ +     K         
Sbjct: 3496 KYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISA 3555

Query: 1718 PDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAA 1777
            P+ + K GS G             + DS   +    ++ SP     P + K  TPL    
Sbjct: 3556 PEKTYKGGSLG----------CQTEADSDTQSPQYLSATSP-----PKDKKRPTPLEIGY 3600

Query: 1778 FEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADE 1837
               +      ++V  APSPP S  +  SP+          P SPG  LES   P      
Sbjct: 3601 SSHLRA---DSTVQLAPSPPKSPKVLYSPIS---------PLSPGKALESAFVPYEKPLP 3648

Query: 1838 DELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVP-TPSAKQ 1879
            D++ P     P    VP  S        +S   P P +P+A +
Sbjct: 3649 DDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADE 3691



 Score = 32.0 bits (71), Expect = 6.5
 Identities = 42/168 (25%), Positives = 60/168 (35%), Gaps = 18/168 (10%)

Query: 1540 ATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL 1599
            AT  PK+   P  + +       A  T + AP+ P S +    P ++P       SP + 
Sbjct: 3583 ATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSP-ISPL------SPGKA 3635

Query: 1600 LIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKD----SPTSPA 1655
            L    V    P E P P  ++P           P  +P +  +   S+ D    SPT+  
Sbjct: 3636 LESAFV----PYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADE 3691

Query: 1656 SVTCKMGATVPQASKGLPAKKGPTALKEV---LVAPAPESTPIITAPT 1700
            S       T    +KG        A K+V   L  P PE     T  T
Sbjct: 3692 SSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEISTGTQST 3739


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score =  211 bits (537), Expect = 6e-54
 Identities = 219/780 (28%), Positives = 303/780 (38%), Gaps = 104/780 (13%)

Query: 997  KGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGA 1056
            K G A  +P  A   P +  P P GSP   P      TP A       G+    PL + A
Sbjct: 9    KAGAAARTP--AARAPGLLTPRPPGSPRPPP----PVTPAALRVLGAAGAVGRKPLAERA 62

Query: 1057 PTTPAATLP--SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPK 1114
                 AT+P  +P+ GP   +   +  P +  P S +G  A P+   +P P ++  P   
Sbjct: 63   GGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS--PGRA 120

Query: 1115 GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT 1174
             G   P   G      +   +   G AT  PK +  +  A   +      TP P  A  +
Sbjct: 121  SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180

Query: 1175 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1234
             AA     + GL  P+P   P  P   P       A+      P+  A   PS  GGL  
Sbjct: 181  RAA---GTEVGLPRPAPSARPRPPTEGPRKSVSS-ASEHSTTEPSPAARRRPSAGGGLQR 236

Query: 1235 PSPKGAP------TTPAATPPSPKGGPATPPPKGAPTP---PAATPPSLKGGLATPPHKG 1285
            P+ +         ++PA + PS +G P  P     P P    A  PP +     TPP K 
Sbjct: 237  PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV-----TPPRKD 291

Query: 1286 APNPAVVTPPSPKGGPATSPPKGAPTPPAA----TPPSPKGSP---------GTPPPKGA 1332
            A         +P  GP +S P   P+P AA     PP+   +P          TP P   
Sbjct: 292  A---------APALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP 342

Query: 1333 PTPPAVTPPSPKGTPTLPATTPS----SKGGPTTPSSKEG-PTPPAATPSHKGGPAMTPP 1387
            P+P A  PPS +  P+ PAT PS    S G PT  ++    P+PP +       P  TPP
Sbjct: 343  PSPSA--PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS-------PLATPP 393

Query: 1388 SPKRGPAIPSP--KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445
             P+  PA+  P  +  P+ PA  PLSP   P+       A    +   +PP   PV    
Sbjct: 394  -PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 452

Query: 1446 APATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL 1505
            +P  S P    ATP S+  P+L A     P  PPA   ++ S++P   P  P P+ AP L
Sbjct: 453  SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP--PPQAPPPLAAPPL 510

Query: 1506 PAVIPSSPKEVP---ATPSSRRDPIAPTATLLSKK--TPATLAPKEALIPPAMTVPSPKK 1560
                P  P + P   ATP  +  P +P A+   +   +P+   P   L  P    P    
Sbjct: 511  QLAKP--PPQAPPALATPPLQALP-SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 567

Query: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620
             P +  P   PA+P+ +    PP   P T    P     L      +P P   P PP+ +
Sbjct: 568  APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL------APGP---PPPPSRS 618

Query: 1621 PPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVT----CKMGATVPQASKGLPAKK 1676
            P S   GP       + TS P         P   A+ +     ++ A  P A    PA  
Sbjct: 619  PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP- 677

Query: 1677 GPTALKEVLVAPAP--------ESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG 1728
             P A +    AP P         +  + T    +GP+    SAT  P   DP    G+ G
Sbjct: 678  -PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPE----SATPAPGALDPGPSPGTSG 732



 Score =  207 bits (528), Expect = 7e-53
 Identities = 230/788 (29%), Positives = 303/788 (38%), Gaps = 101/788 (12%)

Query: 849  SPATTHSPTPPSPKGAPTPSAVTPLSPKG-VTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907
            +P    SP PP P    TP+A+  L   G V   P       +     P+      AP+ 
Sbjct: 26   TPRPPGSPRPPPPV---TPAALRVLGAAGAVGRKPLAERAGGIGGATIPES-----APRA 77

Query: 908  APALSMTSSSPKKARATPAP-KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP 966
             P  S  +SS   A   PA  +G  A P+   +P P ++  P    G   P P       
Sbjct: 78   GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS--PGRASGTTRPGPLGQKGLR 135

Query: 967  AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026
             +   +   G AT +PK +     A   +    P TPSP  A    A       G+    
Sbjct: 136  ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA------GTEVGL 189

Query: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG---PATPSLKGAPTP- 1082
            P P  ++ P   T    K   +A+      P+  A   PS  GG   PA+ SL  + TP 
Sbjct: 190  PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249

Query: 1083 --PAATPPSPKGGPATPS------PKG--APMPPAATPPSPKGGLATPPHKGAPTTPAAT 1132
              PA + PS +G P  P+      PKG  A  PP  TPP      A  P     ++P AT
Sbjct: 250  SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP---LSSSPLAT 306

Query: 1133 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPK 1192
            P SP   L +  P   P TP ++  + +  LATP P          PPSP    A PS +
Sbjct: 307  P-SPSAALQSQAPPTLPATPHSSSLTCQ--LATPLP--------LAPPSPS---APPSLQ 352

Query: 1193 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT---TPAATPP 1249
              P+ PA  P      L +P+ +    T +  P  P   LATP P+  P     P   PP
Sbjct: 353  TLPSPPATPPSQATTSLGSPTLQA---THSFLPSPPLSPLATPPPQAPPALALPPLQAPP 409

Query: 1250 SPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA 1309
            SP   PA+PP     TP    P +L   L   P    P+P V  P SP   P  SP   +
Sbjct: 410  SP---PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP---S 463

Query: 1310 PTPPAATPPS--------PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP- 1360
             TPP+  PPS        P   P +PP   + TPP   PP P   P L    P  +  P 
Sbjct: 464  ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP-PLAAPPLQLAKPPPQAPPA 522

Query: 1361 -TTPSSKEGPTPPAATPSHKGGPAMTPPS---PKRGPAIPSPKGDPTSPAVIPLSPKKAP 1416
              TP  +  P+PPA+ P    G A   PS   P    A P P+  P   A +   P   P
Sbjct: 523  LATPPLQALPSPPASFP----GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 578

Query: 1417 ATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL--PAVTPPS 1474
            A+P  +     P+ G  T  +   ++L  AP      G P  PS     TL  P +   S
Sbjct: 579  ASPTLQAPRRPPTPGPDTSVSGPRLTLALAP------GPPPPPSRSPSSTLSGPDLAGHS 632

Query: 1475 PKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLL 1534
                  P+++    S  +  A  +P     L A  P++    PA P + R   AP A L 
Sbjct: 633  SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRG--APGAPL- 689

Query: 1535 SKKTPATLAPKEA----LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590
                P    P  A     I       S    P    P  +P T   K A+   A   S  
Sbjct: 690  --PWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSR- 746

Query: 1591 KGAPSPKE 1598
                SPK+
Sbjct: 747  ----SPKQ 750



 Score =  203 bits (516), Expect = 2e-51
 Identities = 222/731 (30%), Positives = 292/731 (39%), Gaps = 173/731 (23%)

Query: 907  QAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPA---------------------- 944
            +A A + T ++      TP P G P  P P    TP A                      
Sbjct: 9    KAGAAARTPAARAPGLLTPRPPGSPRPPPP---VTPAALRVLGAAGAVGRKPLAERAGGI 65

Query: 945  --ATPP--SPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAA-------TP 993
              AT P  +P+ GP   +   +  P +  P S +G  A P+   +P P ++       T 
Sbjct: 66   GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125

Query: 994  PSPKG--------------GPATPSPK------------GAPTPPAVTPPSPKGSPAA-- 1025
            P P G              G AT +PK              PTP   +P   + S AA  
Sbjct: 126  PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 185

Query: 1026 ---TPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG---PATPSLKGA 1079
                P P  ++ P   T    K   +A+      P+  A   PS  GG   PA+ SL  +
Sbjct: 186  EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245

Query: 1080 PTP---PAATPPSPKG------GPATPSPKG--APMPPAATPPSPKGGLATPPHKGAPTT 1128
             TP   PA + PS +G       P+ P PKG  A  PP  TPP      A  P     ++
Sbjct: 246  ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP---LSSS 302

Query: 1129 PAATPPSPKGGLATPPPKGAPTTPAAT-------------PPSPKGGLATPPPKGAPTTP 1175
            P AT PSP   L +  P   P TP ++             PPSP    + PP      +P
Sbjct: 303  PLAT-PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP----SAPPSLQTLPSP 357

Query: 1176 AATPPSPKGGLATPSPKGAPT---TPAATPPSPKGGLATPSPKGAPT---TPAATPPSPK 1229
             ATPPS     AT S  G+PT   T +  P  P   LATP P+  P     P   PPSP 
Sbjct: 358  PATPPSQ----ATTS-LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 412

Query: 1230 GG-----LATPSPKG----------APTTPAATPP--SPKGGPATPPPKGAPTPPAATPP 1272
                   LATPSP+           AP +P  +PP  +P   PA+PP   + TPP+  PP
Sbjct: 413  ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472

Query: 1273 SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA 1332
            S    LA PP +  P+P    P SP   P+ +PP  AP PP A PP        PPP+  
Sbjct: 473  S----LAAPPLQVPPSP----PASPPMSPSATPPPQAP-PPLAAPPLQLAK---PPPQ-- 518

Query: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAM------TP 1386
              PPA+  P  +  P+ PA+ P     P +PS+   P  P ATP  +  P +       P
Sbjct: 519  -APPALATPPLQALPSPPASFPGQ--APFSPSASL-PMSPLATPPPQAPPVLAAPLLQVP 574

Query: 1387 PSPKRGPAIPSPKGDPT-------SPAVIPLSPKKAPATPVTREGAATPSKGDL----TP 1435
            PSP   P + +P+  PT       S   + L+    P  P +R  ++T S  DL    + 
Sbjct: 575  PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 634

Query: 1436 PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPA 1495
               TP  L+     S P+GG A  S   D  L A  P +    PAP         + AP 
Sbjct: 635  ATSTPEELR--GYDSGPEGG-AAASPPPDAELAACHPAAWSRGPAPPLAF-----RGAPG 686

Query: 1496 TPAPMGAPTLP 1506
             P P    T P
Sbjct: 687  APLPWPPATGP 697



 Score =  200 bits (508), Expect = 1e-50
 Identities = 200/699 (28%), Positives = 269/699 (38%), Gaps = 76/699 (10%)

Query: 1171 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1230
            A  TPAA  P    GL TP P G+P  P    P+    L      G    P A      G
Sbjct: 13   AARTPAARAP----GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRK--PLAERAGGIG 66

Query: 1231 GLATP--SPKGAPT--------TPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLAT 1280
            G   P  +P+  PT         PA+ PP+   G   PP K     P ++P     G   
Sbjct: 67   GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP-GRASGTTR 125

Query: 1281 PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPP------KGAPT 1334
            P   G     +    +   G AT  PK +     A   +   +PGTP P      + A T
Sbjct: 126  PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 185

Query: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPS------ 1388
               +  P+P   P  P   P       +  S   P+P A      GG    P S      
Sbjct: 186  EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245

Query: 1389 --PKRGPAI--PSPKGDPTSPAVIPLSPK-------KAPATPVTREGAATPSKGDLTPPA 1437
              P   PA   PS +G P +PA  P  PK       + P     R+ AA P+ G L+   
Sbjct: 246  ATPLSSPARSGPSARGTPRAPAH-PSQPKPKGLQALRPPQVTPPRKDAA-PALGPLSSSP 303

Query: 1438 VTPVSLKKAPATSAPKGGPATP-SSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPAT 1496
            +   S   A  + AP   PATP SS     L    P +P  P AP  + T  SP   P +
Sbjct: 304  LATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS 363

Query: 1497 PAP--MGAPTLPAV---IPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551
             A   +G+PTL A    +PS P    ATP  +  P      L +  +P    P   L  P
Sbjct: 364  QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 423

Query: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA---VTPSTYKGAPSPKELLIPPAVTSP 1608
            +   P+      +  P   P +P  +   SPPA   V+PS    + +P  L  PP    P
Sbjct: 424  SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 483

Query: 1609 SPKEA-PTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ 1667
            SP  + P  P+ TPP     P    P      PP  P +L    T P        A+ P 
Sbjct: 484  SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL---ATPPLQALPSPPASFPG 540

Query: 1668 ASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSAT--SPPICPDPSAKNG 1725
             +   P+   P +    L  P P++ P++ AP  + P +  +S T  +P   P P     
Sbjct: 541  QAPFSPSASLPMS---PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 597

Query: 1726 SKGPLST--VAPAPLLPVQKDSSKTAKGKD-ASHSPKGPLAPPESKA--STPLTAAAFEK 1780
              GP  T  +AP P  P  +  S T  G D A HS      P E +   S P   AA   
Sbjct: 598  VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA--- 654

Query: 1781 VLPKPES-------ASVSAAPSPPVSLPLAP-SPVPTLP 1811
              P P++       A+ S  P+PP++   AP +P+P  P
Sbjct: 655  ASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 693



 Score =  196 bits (497), Expect = 3e-49
 Identities = 231/803 (28%), Positives = 292/803 (36%), Gaps = 196/803 (24%)

Query: 944  AATPPSPKGGPATPSPKWAPTPPAATPPSP-----KGGPATPSP--------KGAPTPPA 990
            A TP +   G  TP P  +P PP    P+        G     P         GA  P +
Sbjct: 14   ARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73

Query: 991  ATPPSPKGGPATPSPKGAPTPPAV-----TPPSPKGSPAATPFPKGASTPPAATPPSPKG 1045
            A    P     T S   A  PPA       PP+   SP     P  AS     T P P G
Sbjct: 74   APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS---GTTRPGPLG 130

Query: 1046 SPA-------------ATPLPKGAPTTPAATLPSPKGGPATPSLK------------GAP 1080
                            AT  PK +  +  A   +    P TPS              G P
Sbjct: 131  QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 190

Query: 1081 TP-PAATPPSPKGGP------ATPSPKGAPMPPAATPPSPKGGLATPPHK--GAPTTPAA 1131
             P P+A P  P  GP      A+      P P A   PS  GGL  P  +   +  TP +
Sbjct: 191  RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250

Query: 1132 TPPSPKGGLATPPPKGAPTTPA-ATPPSPKGGLATPPPKGAPTTPAATP---PSPKGGLA 1187
            +P       + P  +G P  PA  + P PKG  A  PP+  P    A P   P     LA
Sbjct: 251  SP-----ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305

Query: 1188 TPSPKGA------PTTPAA----------------TPPSPKGGLATPSPKGAPTTPAATP 1225
            TPSP  A      PT PA                  PPSP    A PS +  P+ PA  P
Sbjct: 306  TPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPS---APPSLQTLPSPPATPP 362

Query: 1226 PSPKGGLATPSPKGA-------PTTPAATPPSPKGGP--ATPPPKGAPTPPAATPPSLKG 1276
                  L +P+ +         P +P ATPP P+  P  A PP +  P+PPA+ P S   
Sbjct: 363  SQATTSLGSPTLQATHSFLPSPPLSPLATPP-PQAPPALALPPLQAPPSPPASPPLS--- 418

Query: 1277 GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP-TPPAATPPSPKGSPGTPPPKGAPTP 1335
             LATP  + APN   V        P  SPP  AP +PPA+ P SP  +P +  P     P
Sbjct: 419  PLATPSPQ-APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 477

Query: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAI 1395
            P   PPSP   P  P  +PS+   P  P       PP A P  +    +  P P+  PA+
Sbjct: 478  PLQVPPSP---PASPPMSPSATPPPQAP-------PPLAAPPLQ----LAKPPPQAPPAL 523

Query: 1396 PSP--KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPK 1453
             +P  +  P+ PA  P     +P+  +     ATP      PP   PV    AP    P 
Sbjct: 524  ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP------PPQAPPV--LAAPLLQVPP 575

Query: 1454 GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSP 1513
              PA+P           T  +P+ PP P    + S P+   A  AP G P  P+  PSS 
Sbjct: 576  SPPASP-----------TLQAPRRPPTPGPDTSVSGPRLTLAL-AP-GPPPPPSRSPSST 622

Query: 1514 KEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPAT 1573
               P               L    + AT  P+E                     +   + 
Sbjct: 623  LSGP--------------DLAGHSSSATSTPEEL--------------------RGYDSG 648

Query: 1574 PSSKEASSPP------AVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPE-- 1625
            P    A+SPP      A  P+ +   P+P     P A         P PPA  P S +  
Sbjct: 649  PEGGAAASPPPDAELAACHPAAWSRGPAP-----PLAFRGAPGAPLPWPPATGPGSADGL 703

Query: 1626 ------KGP--ATPAPKGTPTSP 1640
                  +GP  ATPAP      P
Sbjct: 704  CTIYETEGPESATPAPGALDPGP 726



 Score =  183 bits (465), Expect = 1e-45
 Identities = 220/740 (29%), Positives = 285/740 (38%), Gaps = 116/740 (15%)

Query: 567  PKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSY 626
            P+++P    T S+     +P +       GE  P   PA + TSP  V+S          
Sbjct: 71   PESAPRAGPTRSAGTSSRNPASRPPASGRGERAP---PAKN-TSPGPVSSPGRA------ 120

Query: 627  AGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPK 686
            +G    GPL +  L            A  A      + G    T+  +P   GT S A  
Sbjct: 121  SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP---GTPSPAMA 177

Query: 687  NHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSL---PPAG 743
                  GT   LP    ++   P    P+ + +       A E   + PSP+    P AG
Sbjct: 178  RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS------ASEHSTTEPSPAARRRPSAG 231

Query: 744  TPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGV-SVS 802
               G ++    S +S+  P++S  +  P+      A A            P P G+ ++ 
Sbjct: 232  G--GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS--------QPKPKGLQALR 281

Query: 803  PQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT----- 857
            P    PP K  +      +G LSS  SP+ A+  P  +L  Q     PAT HS +     
Sbjct: 282  PPQVTPPRKDAAPA----LGPLSS--SPL-ATPSPSAALQSQAPPTLPATPHSSSLTCQL 334

Query: 858  -PPSPKGAPTPSAVTPLS--PKGVTLPPKE------TPTPSVVN--LPFPKEGP-ATPAP 905
              P P   P+PSA   L   P     PP +      +PT    +  LP P   P ATP P
Sbjct: 335  ATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 394

Query: 906  KQAPALSMT---------SSSPKKARATPAPKG----------IPASPSPKG---AP-TP 942
            +  PAL++          +S P    ATP+P+            P SP P     AP +P
Sbjct: 395  QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 454

Query: 943  PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGP-----ATPSPKGAPTPPAATPPSPK 997
            PA+ P SP   P + +P     PP   PPSP   P     ATP P+ AP PP A PP   
Sbjct: 455  PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ-AP-PPLAAPPLQL 512

Query: 998  GGPATPSPKGAPTPPAVTPPSPKGS-PAATPFPKGASTPPAATPPSPKGSPAATPLPKGA 1056
              P   +P    TPP    PSP  S P   PF   AS P          SP ATP P+  
Sbjct: 513  AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM---------SPLATPPPQAP 563

Query: 1057 PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGG 1116
            P   A  L  P   PA+P+L+    PP   P +   GP       AP PP     SP   
Sbjct: 564  PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL-APGPPPPPSRSPSST 622

Query: 1117 LATPPHKGAPTTPAATP-------PSPKGGLATPPPKGAPTT---PAATPPSPKGGLATP 1166
            L+ P   G  ++  +TP         P+GG A  PP  A      PAA    P   LA  
Sbjct: 623  LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR 682

Query: 1167 PPKGAPTT-PAATPPSPKGGLA----TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1221
               GAP   P AT P    GL     T  P+ A   P A  P P  G  T   K A    
Sbjct: 683  GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG--TSGGKAAAGAG 740

Query: 1222 A-ATPPSPKGGLATPSPKGA 1240
            A A+  SPK       P GA
Sbjct: 741  AGASSRSPKQARLGELPLGA 760



 Score =  147 bits (370), Expect = 1e-34
 Identities = 178/626 (28%), Positives = 239/626 (38%), Gaps = 98/626 (15%)

Query: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343
            K     A  TP +   G  T  P G+P PP    P+     G     G    P       
Sbjct: 7    KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVG--RKPLAERAGG 64

Query: 1344 KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPT 1403
             G  T+P + P           + GPT  A T S    PA  PP+  RG   P  K   T
Sbjct: 65   IGGATIPESAP-----------RAGPTRSAGTSSR--NPASRPPASGRGERAPPAKN--T 109

Query: 1404 SPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463
            SP  +  SP +A  T  TR G      G          ++ +  AT APK    +  ++ 
Sbjct: 110  SPGPVS-SPGRASGT--TRPGPL----GQKGLRISAEETVARGKATEAPKRSALSAGARR 162

Query: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIP----SSPKEVPAT 1519
            D + P  TP +P   PA  + + ++  +     PAP   P  P   P    SS  E   T
Sbjct: 163  DTSGP--TPGTPS--PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218

Query: 1520 ---PSSRRDPIA-------PTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569
               P++RR P A        + +L S  TP        L  PA + PS + TP  P    
Sbjct: 219  EPSPAARRRPSAGGGLQRPASRSLSSSATP--------LSSPARSGPSARGTPRAPAHPS 270

Query: 1570 APATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVT-SPSPKEAPTPPAVTPPSPEKGP 1628
             P  P   +A  PP VTP     AP+   L   P  T SPS       P   P +P    
Sbjct: 271  QP-KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS 329

Query: 1629 -----ATPAPKGTPTSPPVTPSSLKDSP----TSPASVTCKMGATVPQASKGLPAKKGPT 1679
                 ATP P   P+  P  P SL+  P    T P+  T  +G+   QA+        P+
Sbjct: 330  LTCQLATPLPLAPPS--PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL----PS 383

Query: 1680 ALKEVLVAPAPESTPIITAPTRKGPQTKKSS-ATSPPICPDPSAKNGSKGPL--STVAPA 1736
                 L  P P++ P +  P  + P +  +S   SP   P P A N     L  +  +P 
Sbjct: 384  PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 443

Query: 1737 PLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSP 1796
            P  PVQ           A  SP  P +PP S ++TP + A      P   +  +   PSP
Sbjct: 444  PSPPVQ-----------APFSP--PASPPVSPSATPPSQAP-----PSLAAPPLQVPPSP 485

Query: 1797 PVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPIS--GGVP 1854
            P S P++PS  P  PP+     ++P L L  P     PA     L  +P  P S  G  P
Sbjct: 486  PASPPMSPSATP--PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543

Query: 1855 FQSVLVNMPTPKSAGIPVPTPSAKQP 1880
            F       P+      P+ TP  + P
Sbjct: 544  FS------PSASLPMSPLATPPPQAP 563



 Score =  145 bits (367), Expect = 3e-34
 Identities = 180/614 (29%), Positives = 237/614 (38%), Gaps = 85/614 (13%)

Query: 1298 KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK 1357
            K G A   P  A   P    P P GSP  PPP        +      G   L A      
Sbjct: 9    KAGAAARTP--AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPL-AERAGGI 65

Query: 1358 GGPTTPSS--KEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415
            GG T P S  + GPT  A T S    PA  PP+  RG   P  K   TSP  +  SP +A
Sbjct: 66   GGATIPESAPRAGPTRSAGTSSRN--PASRPPASGRGERAPPAKN--TSPGPVS-SPGRA 120

Query: 1416 PATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSP 1475
              T  TR G      G          ++ +  AT APK    +  ++ D + P  TP +P
Sbjct: 121  SGT--TRPGPL----GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP--TPGTP 172

Query: 1476 KEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIP----SSPKEVPAT---PSSRRDPIA 1528
               PA  + + ++  +     PAP   P  P   P    SS  E   T   P++RR P A
Sbjct: 173  S--PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 230

Query: 1529 -------PTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASS 1581
                    + +L S  TP        L  PA + PS + TP  P     P  P   +A  
Sbjct: 231  GGGLQRPASRSLSSSATP--------LSSPARSGPSARGTPRAPAHPSQPK-PKGLQALR 281

Query: 1582 PPAVTPSTYKGAPSPKELLIPPAVT-SPSPKEAPTPPAVTPPSPEKGP-----ATPAPKG 1635
            PP VTP     AP+   L   P  T SPS       P   P +P         ATP P  
Sbjct: 282  PPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLA 341

Query: 1636 TPTSPPVTPSSLKDSPTSPAS----VTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPE 1691
             P+  P  P SL+  P+ PA+     T  +G+   QA+        P+     L  P P+
Sbjct: 342  PPS--PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL----PSPPLSPLATPPPQ 395

Query: 1692 STPIITAPTRKGPQTKKSSATSPPIC-PDPSAKNGSKGPL--STVAPAPLLPVQKDSSKT 1748
            + P +  P  + P +  +S    P+  P P A N     L  +  +P P  PVQ   S  
Sbjct: 396  APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 455

Query: 1749 AKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESA---SVSAAPSPPVSLPLAPS 1805
            A        P  P A P S+A   L A   + V P P ++   S SA P P    PLA  
Sbjct: 456  AS------PPVSPSATPPSQAPPSLAAPPLQ-VPPSPPASPPMSPSATPPPQAPPPLAAP 508

Query: 1806 PV------PTLPPKQ-----QFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVP 1854
            P+      P  PP       Q LPS P         P +P+    + PL  P P +  V 
Sbjct: 509  PLQLAKPPPQAPPALATPPLQALPSPPASF--PGQAPFSPSASLPMSPLATPPPQAPPVL 566

Query: 1855 FQSVLVNMPTPKSA 1868
               +L   P+P ++
Sbjct: 567  AAPLLQVPPSPPAS 580



 Score =  100 bits (248), Expect = 2e-20
 Identities = 195/832 (23%), Positives = 289/832 (34%), Gaps = 164/832 (19%)

Query: 180 APSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCV--------TPMASIQSGVA--- 228
           A +  +T   + P  + P P G+P PP  V+      +         P+A    G+    
Sbjct: 10  AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69

Query: 229 ---SLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPV 285
              S P+  PT +   +S        +S       P   +  GPVS P   S +T+  P+
Sbjct: 70  IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129

Query: 286 VTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSS 345
                + +   T     ++ G       +S+  +      +GP+    P   + ++   S
Sbjct: 130 GQKGLRISAEET-----VARGKATEAPKRSALSAGARRDTSGPT----PGTPSPAMARRS 180

Query: 346 TGAS--------YPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSG 397
             A          PS R   P    R  V  A+  +    +P+  + PS    +    S 
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240

Query: 398 SL-NVATSFSLSPTTSLILKSSPNATYH-------------YPLV------AQMPVSSVG 437
           SL + AT  S    +    + +P A  H              P V      A   +  + 
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300

Query: 438 TTPLVVTNPC---------TIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPV 488
           ++PL   +P          T+ A P ++       +P     P++   P++P +L   P 
Sbjct: 301 SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPL----PLAPPSPSAPPSLQTLPS 356

Query: 489 APKEPSTQVATTLRIPVSPP----LPDPEDLKNLPSSVLVKFPTQ-------KDLQTVPA 537
            P  P +Q  T+L  P        LP P      P S L   P Q         LQ  P+
Sbjct: 357 PPATPPSQATTSLGSPTLQATHSFLPSP------PLSPLATPPPQAPPALALPPLQAPPS 410

Query: 538 SLEGAPFSPAQAGLTTKKDPTVLPLVQA--APKNSPSFQSTSSSP-EIPLSPEAT---LA 591
                P SP         +   + L+QA  +P  SP  Q+  S P   P+SP AT    A
Sbjct: 411 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 470

Query: 592 KKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPL--------LKSSLITP 643
             SL  P P+  P S   SP     S S         P +A PL           +L TP
Sbjct: 471 PPSLAAP-PLQVPPSPPASP---PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 526

Query: 644 TVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPT 703
            + A P   A   G AP +   +   +  A+P         P+  PV    L  +P  P 
Sbjct: 527 PLQALPSPPASFPGQAPFSPSASLPMSPLATP--------PPQAPPVLAAPLLQVPPSPP 578

Query: 704 ASENC-----PVAPSPQNTCA-PLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHT 757
           AS        P  P P  + + P  TL LAP  P   P PS  P+ T  G    D   H+
Sbjct: 579 ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP---PPPSRSPSSTLSGP---DLAGHS 632

Query: 758 SALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGP 817
           S+     S+P+E    DSG    A++                        PP       P
Sbjct: 633 SS---ATSTPEELRGYDSGPEGGAAAS-----------------------PP-------P 659

Query: 818 DTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKG 877
           D  +    +   P   S  P   L+F+G+  +P     P PP+          T    +G
Sbjct: 660 DAEL----AACHPAAWSRGPAPPLAFRGAPGAPL----PWPPATGPGSADGLCTIYETEG 711

Query: 878 VTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKG 929
              P   TP P  ++ P P  G +            +S SPK+AR    P G
Sbjct: 712 ---PESATPAPGALD-PGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLG 759



 Score = 94.7 bits (234), Expect = 8e-19
 Identities = 159/643 (24%), Positives = 240/643 (37%), Gaps = 111/643 (17%)

Query: 27  PMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSS 86
           P  SALS  A     GPT   P     ++   +      P P+PS     P E P    S
Sbjct: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS 210

Query: 87  S----GTALPLGTAPEAPTFLPNLIGP---PISPAALALASP-MIAPTLKGTPSSSA--- 135
           S     T  P   A   P+    L  P    +S +A  L+SP    P+ +GTP + A   
Sbjct: 211 SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 270

Query: 136 ---PLALVALAPHSV---QKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEP-KTNL 188
              P  L AL P  V   +K +A     L+S P    + S ++ + + P  P+ P  ++L
Sbjct: 271 QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSL 330

Query: 189 NKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKD 248
               +  +P    +PS P  + T+P    TP +   + + S   T   T   + SP +  
Sbjct: 331 TCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGS--PTLQATHSFLPSPPLSP 388

Query: 249 TTISSVLISPQNPGSLS---LKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISL 305
                    PQ P +L+   L+ P SPPA+  LS    P+ T S         P  P +L
Sbjct: 389 LATP----PPQAPPALALPPLQAPPSPPASPPLS----PLATPS---------PQAPNAL 431

Query: 306 GSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNE 365
             HL    Q+ F              S P    +    S   AS P   S  PP      
Sbjct: 432 AVHLL---QAPF--------------SPPPSPPVQAPFSPP-ASPPVSPSATPP-----S 468

Query: 366 VVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHY 425
             P ++AA P+  P     PS  +S   SPS +        L+     + K  P A    
Sbjct: 469 QAPPSLAAPPLQVP-----PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP--- 520

Query: 426 PLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVM 485
           P +A  P+ ++ + P   + P     +P+ +  ++   +PP  + P+           + 
Sbjct: 521 PALATPPLQALPSPP--ASFPGQAPFSPSASLPMSPLATPPPQAPPV-----------LA 567

Query: 486 APVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFS 545
           AP+    PS   + TL+ P  PP P P+   + P   L   P             G P  
Sbjct: 568 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP-------------GPPPP 614

Query: 546 PAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPE----IPLSPEATL-----AKKSLG 596
           P+++  +T   P +     +A       +   S PE        P+A L     A  S G
Sbjct: 615 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 674

Query: 597 EPLPI---GKPASSMTSP--LGVNSSASVIKTDSYAGPDSAGP 634
              P+   G P + +  P   G  S+  +       GP+SA P
Sbjct: 675 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 717



 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 103/370 (27%), Positives = 145/370 (39%), Gaps = 47/370 (12%)

Query: 8   TVPATEQELPQPQAETAVLPMSSALSVTAALGQ---PGPTLPPPCSPAPQQCPLSAAN-- 62
           + P + Q LP P A       +S  S T        P P L P  +P PQ  P  A    
Sbjct: 346 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 405

Query: 63  QASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPM 122
           QA P P P++   +PL  P PQ+ +  A+ L  AP +P   P  +  P SP A    SP 
Sbjct: 406 QAPPSP-PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP-VQAPFSPPASPPVSPS 463

Query: 123 IAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPS 182
             P  +  PS +AP   V   P S   S    P+  T PP      +   + L+ P  P 
Sbjct: 464 ATPPSQAPPSLAAPPLQV---PPSPPASPPMSPS-ATPPPQAPPPLAAPPLQLAKP-PPQ 518

Query: 183 EPKTNLNKVPSEVVPNPKGTPSPPC-IVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAI 241
            P       P+   P  +  PSPP       P+   +P AS+           P + LA 
Sbjct: 519 AP-------PALATPPLQALPSPPASFPGQAPF---SPSASL-----------PMSPLAT 557

Query: 242 ASPQVKDTTISSVL-ISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPD 300
             PQ      + +L + P  P S +L+ P  PP     ++ S P +T +     P  P  
Sbjct: 558 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 617

Query: 301 FPISL--GSHLAPLHQSSFGSVQLL-----GQTGPSALSDPTVKTISVDHSSTGASYPSQ 353
            P S   G  LA    S+  + + L     G  G +A S P    ++  H +  +  P+ 
Sbjct: 618 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA- 676

Query: 354 RSVIPPLPSR 363
               PPL  R
Sbjct: 677 ----PPLAFR 682



 Score = 77.8 bits (190), Expect = 1e-13
 Identities = 137/538 (25%), Positives = 205/538 (38%), Gaps = 95/538 (17%)

Query: 24  AVLPMSSALSVTAALGQPGPTLPP-PCSPAPQQCPLSAANQASPFPSPST----IASTPL 78
           A+   S A      L +P P+  P P +  P++   SA+  ++  PSP+      A   L
Sbjct: 175 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 234

Query: 79  EVPFPQSSSGTALPLGT----------APEAPT------------FLPNLIGPP------ 110
           + P  +S S +A PL +           P AP               P  + PP      
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP 294

Query: 111 ----ISPAALALASPMIA------PTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTS 160
               +S + LA  SP  A      PTL  TP SS+    +A        S + PP+L T 
Sbjct: 295 ALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTL 354

Query: 161 PPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPM 220
           P   A   S +  +L +P      +   + +PS  + +P  TP P       P   + P+
Sbjct: 355 PSPPATPPSQATTSLGSPTL----QATHSFLPSPPL-SPLATPPP----QAPPALALPPL 405

Query: 221 ASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISP-QNPGSLSLKGPVSPPAALSLS 279
                   S P + P + LA  SPQ  +     +L +P   P S  ++ P SPPA+  +S
Sbjct: 406 ----QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 461

Query: 280 TQSLPVVTSSQKTAGP--NTPPDFPIS--LGSHLAPLHQS----SFGSVQLL--GQTGPS 329
             + P   +    A P    PP  P S  +     P  Q+    +   +QL       P 
Sbjct: 462 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 521

Query: 330 ALSDPTVKTISVDHSSTGASYPSQRSVIP--PLPSRNEVVPATVAAFPVVAPSVDKGPST 387
           AL+ P ++ +     S  AS+P Q    P   LP      P   A   + AP +   PS 
Sbjct: 522 ALATPPLQAL----PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 577

Query: 388 ISSITC-------SPSGSLNVA---TSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVG 437
            +S T        +P    +V+    + +L+P        SP++T   P +A    SS  
Sbjct: 578 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS-SSAT 636

Query: 438 TTPLVVTNPCT-----IAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAP 490
           +TP  +    +      AA+P    E+A C     S G      P  P A   AP AP
Sbjct: 637 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG------PAPPLAFRGAPGAP 688


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.303    0.124    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 126,361,225
Number of Sequences: 37866
Number of extensions: 11154287
Number of successful extensions: 377989
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1564
Number of HSP's successfully gapped in prelim test: 3366
Number of HSP's that attempted gapping in prelim test: 45696
Number of HSP's gapped (non-prelim): 91887
length of query: 2078
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1960
effective length of database: 13,779,330
effective search space: 27007486800
effective search space used: 27007486800
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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