Guide to the Human Genome
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Search of human proteins with 16306555

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16306555 potassium channel, subfamily K, member 13 [Homo
sapiens]
         (408 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16306555 potassium channel, subfamily K, member 13 [Homo sapi...   824   0.0  
gi|11545761 potassium channel, subfamily K, member 12 [Homo sapi...   521   e-148
gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens]    134   2e-31
gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens]    129   6e-30
gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens]   117   1e-26
gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]    113   4e-25
gi|14149764 potassium channel, subfamily K, member 16 isoform 2 ...   110   2e-24
gi|20143946 potassium channel, subfamily K, member 10 isoform 3 ...   108   1e-23
gi|20143944 potassium channel, subfamily K, member 10 isoform 2 ...   108   1e-23
gi|10863961 potassium channel, subfamily K, member 10 isoform 1 ...   108   1e-23
gi|205360983 potassium channel, subfamily K, member 16 isoform 3...   108   1e-23
gi|15718767 TRAAK [Homo sapiens]                                      103   3e-22
gi|14589851 potassium channel, subfamily K, member 2 isoform b [...   102   8e-22
gi|126365795 potassium channel, subfamily K, member 2 isoform c ...   102   8e-22
gi|62912487 potassium channel, subfamily K, member 2 isoform a [...   102   8e-22
gi|205360973 potassium channel, subfamily K, member 16 isoform 4...   100   3e-21
gi|205360971 potassium channel, subfamily K, member 16 isoform 1...   100   3e-21
gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens]     96   6e-20
gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens]     95   1e-19
gi|17025230 potassium channel, subfamily K, member 17 isoform 1 ...    84   2e-16
gi|205361107 potassium channel, subfamily K, member 17 isoform 2...    79   6e-15
gi|16118231 potassium channel, subfamily K, member 7 isoform A [...    55   1e-07
gi|5031821 potassium channel, subfamily K, member 7 isoform C [H...    54   3e-07
gi|16118235 potassium channel, subfamily K, member 7 isoform B [...    54   3e-07
gi|16118233 potassium channel, subfamily K, member 7 isoform B [...    54   3e-07
gi|32469495 potassium channel, subfamily K, member 18 [Homo sapi...    46   5e-05
gi|41349443 potassium channel, subfamily T, member 2 [Homo sapiens]    39   0.006
gi|240255505 potassium channel, subfamily T, member 1 [Homo sapi...    38   0.019
gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]    33   0.36 
gi|157074214 potassium channel, subfamily U, member 1 [Homo sapi...    33   0.61 

>gi|16306555 potassium channel, subfamily K, member 13 [Homo
           sapiens]
          Length = 408

 Score =  824 bits (2129), Expect = 0.0
 Identities = 408/408 (100%), Positives = 408/408 (100%)

Query: 1   MAGRGFSWGPGHLNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANF 60
           MAGRGFSWGPGHLNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANF
Sbjct: 1   MAGRGFSWGPGHLNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANF 60

Query: 61  SRGHNLSRDELRGFLRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPAT 120
           SRGHNLSRDELRGFLRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPAT
Sbjct: 61  SRGHNLSRDELRGFLRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPAT 120

Query: 121 VGGKIFLIFYGLVGCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAG 180
           VGGKIFLIFYGLVGCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAG
Sbjct: 121 VGGKIFLIFYGLVGCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAG 180

Query: 181 QCEVDSLAGWKPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGF 240
           QCEVDSLAGWKPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGF
Sbjct: 181 QCEVDSLAGWKPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGF 240

Query: 241 GDLVSSQNAHYESQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLNWILRKMDSGCCP 300
           GDLVSSQNAHYESQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLNWILRKMDSGCCP
Sbjct: 241 GDLVSSQNAHYESQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLNWILRKMDSGCCP 300

Query: 301 QCQRGLLRSRRNVVMPGSVRNRCNISIETDGVAESDTDGRRLSGEMISMKDLLAANKASL 360
           QCQRGLLRSRRNVVMPGSVRNRCNISIETDGVAESDTDGRRLSGEMISMKDLLAANKASL
Sbjct: 301 QCQRGLLRSRRNVVMPGSVRNRCNISIETDGVAESDTDGRRLSGEMISMKDLLAANKASL 360

Query: 361 AILQKQLSEMANGCPHQTSTLARDNEFSGGVGAFAIMNNRLAETSGDR 408
           AILQKQLSEMANGCPHQTSTLARDNEFSGGVGAFAIMNNRLAETSGDR
Sbjct: 361 AILQKQLSEMANGCPHQTSTLARDNEFSGGVGAFAIMNNRLAETSGDR 408


>gi|11545761 potassium channel, subfamily K, member 12 [Homo
           sapiens]
          Length = 430

 Score =  521 bits (1341), Expect = e-148
 Identities = 262/400 (65%), Positives = 304/400 (76%), Gaps = 3/400 (0%)

Query: 12  HLNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHNLSRDEL 71
           HLNED  RF+LLAALI LYL+ GA VFSALE   E +A+ RW   L NFS  H ++  EL
Sbjct: 31  HLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEPEL 90

Query: 72  RGFLRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYG 131
           R FLRHYE A  AG+R D +RPRWDF GAFYFVGTVVSTIGFGMTTPATVGGK FLI YG
Sbjct: 91  RAFLRHYEAALAAGVRADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYG 150

Query: 132 LVGCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWK 191
           L GC+ TILFFNLFLER+I+++A+IM++C +RQLRR G LP    + +   E DSLAGWK
Sbjct: 151 LFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWK 210

Query: 192 PSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHY 251
           PSVY+V+LIL   ++L+SCCASAMYT +EGW Y DSLYFCFV FSTIGFGDLVSSQ+A Y
Sbjct: 211 PSVYHVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAY 270

Query: 252 ESQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLNWILRKMDSGCCPQC--QRGLLRS 309
            +QGLYR  NF+FIL+GVCCIYSLFNVISILIKQ LNW+LRK+   CC +C    G   +
Sbjct: 271 RNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQVLNWMLRKLSCRCCARCCPAPGAPLA 330

Query: 310 RRNVVMPGSVRNRCNISIETDGVA-ESDTDGRRLSGEMISMKDLLAANKASLAILQKQLS 368
           RRN + PGS   R   ++  D  A +SD +GRRLSGE+ISM+DL A+NK SLA+LQKQLS
Sbjct: 331 RRNAITPGSRLRRRLAALGADPAARDSDAEGRRLSGELISMRDLTASNKVSLALLQKQLS 390

Query: 369 EMANGCPHQTSTLARDNEFSGGVGAFAIMNNRLAETSGDR 408
           E ANG P       R N FSGGVGA  IMNNRLAETS  R
Sbjct: 391 ETANGYPRSVCVNTRQNGFSGGVGALGIMNNRLAETSASR 430


>gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens]
          Length = 394

 Score =  134 bits (336), Expect = 2e-31
 Identities = 88/270 (32%), Positives = 135/270 (50%), Gaps = 31/270 (11%)

Query: 13  LNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHNLSRDELR 72
           +   N R L L      YLL GAAVF ALE   E   +QR E R       +NLS+    
Sbjct: 1   MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGG-- 58

Query: 73  GFLRHYEEATRAGIRVDNVRP--RWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFY 130
                YEE  R  +R+   +   +W F G+FYF  TV++TIG+G   P+T GGK+F +FY
Sbjct: 59  -----YEELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFY 113

Query: 131 GLVGCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGW 190
            L+G   T++ F    ER+ T++ Y++                 + K  G    D     
Sbjct: 114 ALLGIPLTLVMFQSLGERINTLVRYLL---------------HRAKKGLGMRRAD----- 153

Query: 191 KPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQ-NA 249
             S+  ++LI   + I   C  +A ++  E W++F + Y+CF+  +TIGFGD V+ Q + 
Sbjct: 154 -VSMANMVLIGFFSCISTLCIGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQ 212

Query: 250 HYESQGLYRFANFVFILMGVCCIYSLFNVI 279
             ++Q  Y   +FV+IL G+  I +  N++
Sbjct: 213 ALQTQPQYVAFSFVYILTGLTVIGAFLNLV 242


>gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens]
          Length = 374

 Score =  129 bits (323), Expect = 6e-30
 Identities = 80/270 (29%), Positives = 131/270 (48%), Gaps = 31/270 (11%)

Query: 13  LNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHNLSRDELR 72
           +   N R L L      YLL GAAVF ALE  HE + +++ +         +N+S ++ R
Sbjct: 1   MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYR 60

Query: 73  GF--LRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFY 130
               +    E  RAG++       W F G+FYF  TV++TIG+G   P T  GK F +FY
Sbjct: 61  QLELVILQSEPHRAGVQ-------WKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFY 113

Query: 131 GLVGCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGW 190
            ++G   T++ F    ER+ T + Y++K   +    R   +  E++   G          
Sbjct: 114 AVLGIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVG---------- 163

Query: 191 KPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQ-NA 249
                      C  ++   C  +A ++  E WS+F + Y+CF+  +TIGFGD V+ Q   
Sbjct: 164 --------FFSCMGTL---CIGAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKG 212

Query: 250 HYESQGLYRFANFVFILMGVCCIYSLFNVI 279
             + + LY   +F++IL+G+  I +  N++
Sbjct: 213 ALQKKPLYVAFSFMYILVGLTVIGAFLNLV 242


>gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens]
          Length = 330

 Score =  117 bits (294), Expect = 1e-26
 Identities = 90/311 (28%), Positives = 146/311 (46%), Gaps = 36/311 (11%)

Query: 23  LAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHNLSRDELRGFLRHYEEAT 82
           L    + YLL GAAVF ALE   E   ++   ++     R    S ++       Y E  
Sbjct: 11  LVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAED-------YRELE 63

Query: 83  RAGIRVDNVRP--RWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSSTIL 140
           R  ++ +  R   +W F G+FYF  TV++TIG+G   P T  GK+F +FY L+G   T++
Sbjct: 64  RLALQAEPHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLTLV 123

Query: 141 FFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSVYYVMLI 200
            F    ERL  ++  ++ +       R   +  E+L  AG                  L+
Sbjct: 124 TFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAG------------------LL 165

Query: 201 LCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHYESQGL-YRF 259
            C A++ +   A   ++  EGW++F + Y+CF+  +TIGFGD V+ Q+     + L Y  
Sbjct: 166 ACAATLALGAVA---FSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVA 222

Query: 260 ANFVFILMGVCCIYSLFNVISI-LIKQSLNWILR--KMDSGCCPQC--QRGLLRSRRNVV 314
            +F++IL+G+  I +  N++ +  +  S +W  R  +  S   P     RGL   RR   
Sbjct: 223 FSFLYILLGLTVIGAFLNLVVLRFLVASADWPERAARPPSPRPPGAPESRGLWLPRRPAR 282

Query: 315 MPGSVRNRCNI 325
             GS    C++
Sbjct: 283 SVGSASVFCHV 293


>gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]
          Length = 336

 Score =  113 bits (282), Expect = 4e-25
 Identities = 79/254 (31%), Positives = 124/254 (48%), Gaps = 25/254 (9%)

Query: 20  FLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHN-LSRDELRGFLRHY 78
           FL+L  L  LYL+ GA VFS++EL +E   +Q   +    F   H  LS  +L  FL   
Sbjct: 25  FLVLGYL--LYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRV 82

Query: 79  EEATRAGIRVDNVRP---RWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGC 135
            EA+  G+ V +       WDFT A +F  TV+ST G+G T P + GGK F I Y ++G 
Sbjct: 83  LEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGI 142

Query: 136 SSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSVY 195
             T+LF    ++R+               + RR  L    ++     +V ++      V+
Sbjct: 143 PFTLLFLTAVVQRITV------------HVTRRPVL-YFHIRWGFSKQVVAI------VH 183

Query: 196 YVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHYESQG 255
            V+L   T S      A+      + W++ +S YFCF++ STIG GD V  +  + + + 
Sbjct: 184 AVLLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRE 243

Query: 256 LYRFANFVFILMGV 269
           LY+     ++L+G+
Sbjct: 244 LYKIGITCYLLLGL 257


>gi|14149764 potassium channel, subfamily K, member 16 isoform 2
           [Homo sapiens]
          Length = 309

 Score =  110 bits (275), Expect = 2e-24
 Identities = 81/286 (28%), Positives = 136/286 (47%), Gaps = 31/286 (10%)

Query: 19  RFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHN-LSRDELRGFLRH 77
           R L L    V YLL GA +F  LE   E Q++ +++     F   +  L +  +  F++ 
Sbjct: 13  RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQV 72

Query: 78  YEEATRAGI--RVDNVRP-RWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVG 134
             EA   G+  + ++  P  WDF  +F+F GTVV+TIG+G   P+T  G++F +FY L+G
Sbjct: 73  IMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132

Query: 135 CSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSV 194
               ++F N     L           H   + R    P+ S       +V  + G     
Sbjct: 133 IPLNVIFLNHLGTGL---------RAHLAAIERWEDRPRRS-------QVLQVLG----- 171

Query: 195 YYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLV--SSQNAHYE 252
             + L L   +++I      +++ +EGWS+ +  YF F+  STIGFGD V  +  + HY 
Sbjct: 172 --LALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYI 229

Query: 253 SQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLNWILRKMDSGC 298
           S  +YR    ++IL+G+  +  +  +  +L+ +     L  +  GC
Sbjct: 230 S--VYRSLAAIWILLGLAWLALILPLGPLLLHRCCQLWLLSLRQGC 273


>gi|20143946 potassium channel, subfamily K, member 10 isoform 3
           [Homo sapiens]
          Length = 543

 Score =  108 bits (269), Expect = 1e-23
 Identities = 80/267 (29%), Positives = 124/267 (46%), Gaps = 39/267 (14%)

Query: 26  LIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHN-LSRDELRGFLRHYEEATRA 84
           ++V+YL+ G  VF ALE   E   K       A F R H  +S  EL   ++H  +A  A
Sbjct: 83  VVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNA 142

Query: 85  GI----RVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSSTIL 140
           G+       N    WD   AF+F GTV++TIG+G   P+T GGKIF I Y + G    I 
Sbjct: 143 GVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG----IP 198

Query: 141 FFNLFL----ERLITI----IAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKP 192
            F   L    ++L TI    IA + K   ++Q+ +                       K 
Sbjct: 199 LFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQT----------------------KI 236

Query: 193 SVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHYE 252
            V   +L +    I+     + ++  IEGW+  +S+YF  V  +T+GFGD V+  NA   
Sbjct: 237 RVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGIN 296

Query: 253 SQGLYRFANFVFILMGVCCIYSLFNVI 279
            +  Y+   + +IL+G+    ++ ++I
Sbjct: 297 YREWYKPLVWFWILVGLAYFAAVLSMI 323


>gi|20143944 potassium channel, subfamily K, member 10 isoform 2
           [Homo sapiens]
          Length = 543

 Score =  108 bits (269), Expect = 1e-23
 Identities = 80/267 (29%), Positives = 124/267 (46%), Gaps = 39/267 (14%)

Query: 26  LIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHN-LSRDELRGFLRHYEEATRA 84
           ++V+YL+ G  VF ALE   E   K       A F R H  +S  EL   ++H  +A  A
Sbjct: 83  VVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNA 142

Query: 85  GI----RVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSSTIL 140
           G+       N    WD   AF+F GTV++TIG+G   P+T GGKIF I Y + G    I 
Sbjct: 143 GVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG----IP 198

Query: 141 FFNLFL----ERLITI----IAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKP 192
            F   L    ++L TI    IA + K   ++Q+ +                       K 
Sbjct: 199 LFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQT----------------------KI 236

Query: 193 SVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHYE 252
            V   +L +    I+     + ++  IEGW+  +S+YF  V  +T+GFGD V+  NA   
Sbjct: 237 RVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGIN 296

Query: 253 SQGLYRFANFVFILMGVCCIYSLFNVI 279
            +  Y+   + +IL+G+    ++ ++I
Sbjct: 297 YREWYKPLVWFWILVGLAYFAAVLSMI 323


>gi|10863961 potassium channel, subfamily K, member 10 isoform 1
           [Homo sapiens]
          Length = 538

 Score =  108 bits (269), Expect = 1e-23
 Identities = 80/267 (29%), Positives = 124/267 (46%), Gaps = 39/267 (14%)

Query: 26  LIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHN-LSRDELRGFLRHYEEATRA 84
           ++V+YL+ G  VF ALE   E   K       A F R H  +S  EL   ++H  +A  A
Sbjct: 78  VVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNA 137

Query: 85  GI----RVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSSTIL 140
           G+       N    WD   AF+F GTV++TIG+G   P+T GGKIF I Y + G    I 
Sbjct: 138 GVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG----IP 193

Query: 141 FFNLFL----ERLITI----IAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKP 192
            F   L    ++L TI    IA + K   ++Q+ +                       K 
Sbjct: 194 LFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQT----------------------KI 231

Query: 193 SVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHYE 252
            V   +L +    I+     + ++  IEGW+  +S+YF  V  +T+GFGD V+  NA   
Sbjct: 232 RVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGIN 291

Query: 253 SQGLYRFANFVFILMGVCCIYSLFNVI 279
            +  Y+   + +IL+G+    ++ ++I
Sbjct: 292 YREWYKPLVWFWILVGLAYFAAVLSMI 318


>gi|205360983 potassium channel, subfamily K, member 16 isoform 3
           [Homo sapiens]
          Length = 294

 Score =  108 bits (269), Expect = 1e-23
 Identities = 80/282 (28%), Positives = 136/282 (48%), Gaps = 32/282 (11%)

Query: 19  RFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHN-LSRDELRGFLRH 77
           R L L    V YLL GA +F  LE   E Q++ +++     F   +  L +  +  F++ 
Sbjct: 13  RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQV 72

Query: 78  YEEATRAGI--RVDNVRP-RWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVG 134
             EA   G+  + ++  P  WDF  +F+F GTVV+TIG+G   P+T  G++F +FY L+G
Sbjct: 73  IMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132

Query: 135 CSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSV 194
               ++F N     L           H   + R    P+ S       +V  + G     
Sbjct: 133 IPLNVIFLNHLGTGL---------RAHLAAIERWEDRPRRS-------QVLQVLG----- 171

Query: 195 YYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLV--SSQNAHYE 252
             + L L   +++I      +++ +EGWS+ +  YF F+  STIGFGD V  +  + HY 
Sbjct: 172 --LALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYI 229

Query: 253 SQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLN-WILRK 293
           S  +YR    ++IL+G+  +  +  +  +L+ +    W+L +
Sbjct: 230 S--VYRSLAAIWILLGLAWLALILPLGPLLLHRCCQLWLLSR 269


>gi|15718767 TRAAK [Homo sapiens]
          Length = 393

 Score =  103 bits (257), Expect = 3e-22
 Identities = 81/281 (28%), Positives = 130/281 (46%), Gaps = 41/281 (14%)

Query: 21  LLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHNLSRDELRGFL-RHYE 79
           L L AL++LYL+ GA VF ALE  HE+QA++   E    F R H    D+  G L +   
Sbjct: 7   LALLALVLLYLVSGALVFRALEQPHEQQAQRELGEVREKFLRAHPCVSDQELGLLIKEVA 66

Query: 80  EATRAGIRVD------NVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLV 133
           +A   G   +      +    WD   AF+F GT+++TIG+G     T  G++F IFY LV
Sbjct: 67  DALGGGADPETNSTSNSSHSAWDLGSAFFFSGTIITTIGYGNVALRTDAGRLFCIFYALV 126

Query: 134 GCSSTILFFNLFL----ERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAG 189
           G    I  F + L    +RL + + + +   H   +  +  +P E ++            
Sbjct: 127 G----IPLFGILLAGVGDRLGSSLRHGIG--HIEAIFLKWHVPPELVR------------ 168

Query: 190 WKPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNA 249
               V   ML L    +L     + ++  +E WS  +++YF  V  +T+GFGD V+  + 
Sbjct: 169 ----VLSAMLFLLIGCLLFVLTPTFVFCYMEDWSKLEAIYFVIVTLTTVGFGDYVAGADP 224

Query: 250 HYESQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLNWI 290
             +S   Y+   + +IL+G+    S+   I        NW+
Sbjct: 225 RQDSPA-YQPLVWFWILLGLAYFASVLTTIG-------NWL 257


>gi|14589851 potassium channel, subfamily K, member 2 isoform b
           [Homo sapiens]
          Length = 411

 Score =  102 bits (253), Expect = 8e-22
 Identities = 81/268 (30%), Positives = 121/268 (45%), Gaps = 42/268 (15%)

Query: 26  LIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHN-LSRDELRGFLRHYEEATRA 84
           ++VLYL+ GA VF ALE  HE   +     +   F   H+ ++  EL   ++    A  A
Sbjct: 53  VVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINA 112

Query: 85  GI----RVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSSTIL 140
           GI       N    WD   +F+F GTV++TIGFG  +P T GGKIF I Y L+G    I 
Sbjct: 113 GIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLG----IP 168

Query: 141 FFNLFL----ERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSVYY 196
            F   L    ++L TI               +G    E          D+   W  S   
Sbjct: 169 LFGFLLAGVGDQLGTIFG-------------KGIAKVE----------DTFIKWNVSQTK 205

Query: 197 VMLILCTASILISC-----CASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHY 251
           + +I     IL  C       + ++  IEGWS  D++YF  +  +TIGFGD V+   +  
Sbjct: 206 IRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAG-GSDI 264

Query: 252 ESQGLYRFANFVFILMGVCCIYSLFNVI 279
           E    Y+   + +IL+G+    ++ ++I
Sbjct: 265 EYLDFYKPVVWFWILVGLAYFAAVLSMI 292


>gi|126365795 potassium channel, subfamily K, member 2 isoform c
           [Homo sapiens]
          Length = 426

 Score =  102 bits (253), Expect = 8e-22
 Identities = 81/268 (30%), Positives = 121/268 (45%), Gaps = 42/268 (15%)

Query: 26  LIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHN-LSRDELRGFLRHYEEATRA 84
           ++VLYL+ GA VF ALE  HE   +     +   F   H+ ++  EL   ++    A  A
Sbjct: 68  VVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINA 127

Query: 85  GI----RVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSSTIL 140
           GI       N    WD   +F+F GTV++TIGFG  +P T GGKIF I Y L+G    I 
Sbjct: 128 GIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLG----IP 183

Query: 141 FFNLFL----ERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSVYY 196
            F   L    ++L TI               +G    E          D+   W  S   
Sbjct: 184 LFGFLLAGVGDQLGTIFG-------------KGIAKVE----------DTFIKWNVSQTK 220

Query: 197 VMLILCTASILISC-----CASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHY 251
           + +I     IL  C       + ++  IEGWS  D++YF  +  +TIGFGD V+   +  
Sbjct: 221 IRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAG-GSDI 279

Query: 252 ESQGLYRFANFVFILMGVCCIYSLFNVI 279
           E    Y+   + +IL+G+    ++ ++I
Sbjct: 280 EYLDFYKPVVWFWILVGLAYFAAVLSMI 307


>gi|62912487 potassium channel, subfamily K, member 2 isoform a
           [Homo sapiens]
          Length = 422

 Score =  102 bits (253), Expect = 8e-22
 Identities = 81/268 (30%), Positives = 121/268 (45%), Gaps = 42/268 (15%)

Query: 26  LIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHN-LSRDELRGFLRHYEEATRA 84
           ++VLYL+ GA VF ALE  HE   +     +   F   H+ ++  EL   ++    A  A
Sbjct: 64  VVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINA 123

Query: 85  GI----RVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSSTIL 140
           GI       N    WD   +F+F GTV++TIGFG  +P T GGKIF I Y L+G    I 
Sbjct: 124 GIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLG----IP 179

Query: 141 FFNLFL----ERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSVYY 196
            F   L    ++L TI               +G    E          D+   W  S   
Sbjct: 180 LFGFLLAGVGDQLGTIFG-------------KGIAKVE----------DTFIKWNVSQTK 216

Query: 197 VMLILCTASILISC-----CASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHY 251
           + +I     IL  C       + ++  IEGWS  D++YF  +  +TIGFGD V+   +  
Sbjct: 217 IRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAG-GSDI 275

Query: 252 ESQGLYRFANFVFILMGVCCIYSLFNVI 279
           E    Y+   + +IL+G+    ++ ++I
Sbjct: 276 EYLDFYKPVVWFWILVGLAYFAAVLSMI 303


>gi|205360973 potassium channel, subfamily K, member 16 isoform 4
           [Homo sapiens]
          Length = 262

 Score =  100 bits (248), Expect = 3e-21
 Identities = 69/230 (30%), Positives = 110/230 (47%), Gaps = 27/230 (11%)

Query: 19  RFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHN-LSRDELRGFLRH 77
           R L L    V YLL GA +F  LE   E Q++ +++     F   +  L +  +  F++ 
Sbjct: 13  RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQV 72

Query: 78  YEEATRAGI--RVDNVRP-RWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVG 134
             EA   G+  + ++  P  WDF  +F+F GTVV+TIG+G   P+T  G++F +FY L+G
Sbjct: 73  IMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132

Query: 135 CSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSV 194
               ++F N     L           H   + R    P+ S       +V  + G     
Sbjct: 133 IPLNVIFLNHLGTGL---------RAHLAAIERWEDRPRRS-------QVLQVLG----- 171

Query: 195 YYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLV 244
             + L L   +++I      +++ +EGWS+ +  YF F+  STIGFGD V
Sbjct: 172 --LALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV 219


>gi|205360971 potassium channel, subfamily K, member 16 isoform 1
           [Homo sapiens]
          Length = 322

 Score =  100 bits (248), Expect = 3e-21
 Identities = 69/230 (30%), Positives = 110/230 (47%), Gaps = 27/230 (11%)

Query: 19  RFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHN-LSRDELRGFLRH 77
           R L L    V YLL GA +F  LE   E Q++ +++     F   +  L +  +  F++ 
Sbjct: 13  RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQV 72

Query: 78  YEEATRAGI--RVDNVRP-RWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVG 134
             EA   G+  + ++  P  WDF  +F+F GTVV+TIG+G   P+T  G++F +FY L+G
Sbjct: 73  IMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132

Query: 135 CSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSV 194
               ++F N     L           H   + R    P+ S       +V  + G     
Sbjct: 133 IPLNVIFLNHLGTGL---------RAHLAAIERWEDRPRRS-------QVLQVLG----- 171

Query: 195 YYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLV 244
             + L L   +++I      +++ +EGWS+ +  YF F+  STIGFGD V
Sbjct: 172 --LALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV 219


>gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens]
          Length = 499

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 71/258 (27%), Positives = 119/258 (46%), Gaps = 26/258 (10%)

Query: 22  LLAALIVLYLLGGAAVFSALELAHERQAKQRW-EERLANFSRGHNLSRDELRGFLRHYEE 80
           LL + I+ YL  GAA+F  LE  H ++AK+ +  ++L        L ++ L   L    +
Sbjct: 7   LLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSD 66

Query: 81  ATRAGIRVDNVRP--RWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSST 138
           A   G+ +   +    W++  A  F  TV++TIG+G   P T  G++F +FYGL G    
Sbjct: 67  AAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFG---- 122

Query: 139 ILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSVYYVM 198
                  +   +T I+ + K    R  R    L +  +         SL   K  +   +
Sbjct: 123 -------VPLCLTWISALGKFFGGRAKRLGQFLTKRGV---------SLR--KAQITCTV 164

Query: 199 LILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHYESQGLYR 258
           + +    ++       ++   EGW+Y + LY+ F+  STIGFGD V+  N       LYR
Sbjct: 165 IFIVWGVLVHLVIPPFVFMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYR 224

Query: 259 FANFVFILMGVCCIYSLF 276
           +   ++I +G+  + SLF
Sbjct: 225 YFVELWIYLGLAWL-SLF 241


>gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens]
          Length = 313

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 66/258 (25%), Positives = 112/258 (43%), Gaps = 36/258 (13%)

Query: 25  ALIVLYLLGGAAVFSALELAHERQAKQRWEERLANF-SRGHNLSRDELRGFLRHYEEATR 83
           A    YL+ GA + + LE  HE + +   E   A    R   ++   L  F+     A R
Sbjct: 12  AAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAGR 71

Query: 84  AGIRV--------DNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGC 135
            G  V        +   P WDF  A +F  T+++T+G+G TTP T  GK F I + L+G 
Sbjct: 72  LGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGV 131

Query: 136 SSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSVY 195
            +T+L      +RL  ++ ++  S                        +    GW P   
Sbjct: 132 PTTMLLLTASAQRLSLLLTHVPLSW-----------------------LSMRWGWDPRRA 168

Query: 196 YVMLILCTASILISCC---ASAMYTPI-EGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHY 251
               ++    ++++ C    + ++  + E WS+ D+ YFCF++ STIG GD V  +    
Sbjct: 169 ACWHLVALLGVVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQ 228

Query: 252 ESQGLYRFANFVFILMGV 269
             + LY+    V++ +G+
Sbjct: 229 PYRALYKVLVTVYLFLGL 246



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 7/58 (12%)

Query: 95  WDFTGAFYFVGTVVSTIGFGMTTPATVGG-------KIFLIFYGLVGCSSTILFFNLF 145
           W F  AFYF    +STIG G   P    G       K+ +  Y  +G  + +L    F
Sbjct: 199 WSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLVLQTF 256


>gi|17025230 potassium channel, subfamily K, member 17 isoform 1
           [Homo sapiens]
          Length = 332

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 69/266 (25%), Positives = 117/266 (43%), Gaps = 32/266 (12%)

Query: 21  LLLAALIVLYLLGGAAVFSALELAHERQAKQRWE----ERLANFSRGHNLSRDELRGFLR 76
           +LL    + YL  G  VF  LE    + + + ++    E L NF+    L R  L   +R
Sbjct: 23  VLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTC---LDRPALDSLIR 79

Query: 77  HYEEATRAGIRV---DNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLV 133
              +A + G  +        RW+  G+F+F  + ++TIG+G  +P T+  ++F IF+ LV
Sbjct: 80  DVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALV 139

Query: 134 GCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPS 193
           G    ++  N         + ++M+        R G   Q+  K         LAG    
Sbjct: 140 GIPLNLVVLNR--------LGHLMQQGVNHWASRLGGTWQDPDK------ARWLAGSGAL 185

Query: 194 VYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHYES 253
           +  ++L L    +L        ++ +EGWSY +  YF F+  ST+GFGD V   N     
Sbjct: 186 LSGLLLFLLLPPLL--------FSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQRY 237

Query: 254 QGLYRFANFVFILMGVCCIYSLFNVI 279
              Y+    ++IL G+  +  +  +I
Sbjct: 238 PLWYKNMVSLWILFGMAWLALIIKLI 263


>gi|205361107 potassium channel, subfamily K, member 17 isoform 2
           [Homo sapiens]
          Length = 271

 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 63/231 (27%), Positives = 104/231 (45%), Gaps = 32/231 (13%)

Query: 21  LLLAALIVLYLLGGAAVFSALELAHERQAKQRWE----ERLANFSRGHNLSRDELRGFLR 76
           +LL    + YL  G  VF  LE    + + + ++    E L NF+    L R  L   +R
Sbjct: 23  VLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTC---LDRPALDSLIR 79

Query: 77  HYEEATRAGIRV---DNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLV 133
              +A + G  +        RW+  G+F+F  + ++TIG+G  +P T+  ++F IF+ LV
Sbjct: 80  DVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALV 139

Query: 134 GCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPS 193
           G    ++  N         + ++M+        R G   Q+  K         LAG    
Sbjct: 140 GIPLNLVVLNR--------LGHLMQQGVNHWASRLGGTWQDPDK------ARWLAGSGAL 185

Query: 194 VYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLV 244
           +  ++L L    +L        ++ +EGWSY +  YF F+  ST+GFGD V
Sbjct: 186 LSGLLLFLLLPPLL--------FSHMEGWSYTEGFYFAFITLSTVGFGDYV 228


>gi|16118231 potassium channel, subfamily K, member 7 isoform A
           [Homo sapiens]
          Length = 307

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 61/261 (23%), Positives = 103/261 (39%), Gaps = 31/261 (11%)

Query: 18  ARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHNL-----SRDELR 72
           +R+ LL    +L L  GA VF ALE     + +      LA F   H       + +EL 
Sbjct: 8   SRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELL 67

Query: 73  GFLRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGL 132
           G     +    + +   +    WD   A  F  ++++T G+G   P + GGK F + Y  
Sbjct: 68  GTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAA 127

Query: 133 VGCSSTILFFNLFLERLITIIA--YIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGW 190
           +G  +++         L+ +++      + H +    R AL Q                 
Sbjct: 128 LGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQA---------------- 171

Query: 191 KPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLV--SSQN 248
                 V L L  AS  +   A  ++      S   ++YFCF + STIG  DL+    ++
Sbjct: 172 ------VALGLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRS 225

Query: 249 AHYESQGLYRFANFVFILMGV 269
            H     L + A   ++L+G+
Sbjct: 226 LHPVIYHLGQLALLGYLLLGL 246


>gi|5031821 potassium channel, subfamily K, member 7 isoform C [Homo
           sapiens]
          Length = 257

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 56/234 (23%), Positives = 91/234 (38%), Gaps = 29/234 (12%)

Query: 18  ARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHNL-----SRDELR 72
           +R+ LL    +L L  GA VF ALE     + +      LA F   H       + +EL 
Sbjct: 8   SRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELL 67

Query: 73  GFLRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGL 132
           G     +    + +   +    WD   A  F  ++++T G+G   P + GGK F + Y  
Sbjct: 68  GTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAA 127

Query: 133 VGCSSTILFFNLFLERLITIIA--YIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGW 190
           +G  +++         L+ +++      + H +    R AL Q                 
Sbjct: 128 LGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQA---------------- 171

Query: 191 KPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLV 244
                 V L L  AS  +   A  ++      S   ++YFCF + STIG  DL+
Sbjct: 172 ------VALGLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLL 219


>gi|16118235 potassium channel, subfamily K, member 7 isoform B
           [Homo sapiens]
          Length = 252

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 56/234 (23%), Positives = 91/234 (38%), Gaps = 29/234 (12%)

Query: 18  ARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHNL-----SRDELR 72
           +R+ LL    +L L  GA VF ALE     + +      LA F   H       + +EL 
Sbjct: 8   SRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELL 67

Query: 73  GFLRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGL 132
           G     +    + +   +    WD   A  F  ++++T G+G   P + GGK F + Y  
Sbjct: 68  GTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAA 127

Query: 133 VGCSSTILFFNLFLERLITIIA--YIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGW 190
           +G  +++         L+ +++      + H +    R AL Q                 
Sbjct: 128 LGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQA---------------- 171

Query: 191 KPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLV 244
                 V L L  AS  +   A  ++      S   ++YFCF + STIG  DL+
Sbjct: 172 ------VALGLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLL 219


>gi|16118233 potassium channel, subfamily K, member 7 isoform B
           [Homo sapiens]
          Length = 252

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 56/234 (23%), Positives = 91/234 (38%), Gaps = 29/234 (12%)

Query: 18  ARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHNL-----SRDELR 72
           +R+ LL    +L L  GA VF ALE     + +      LA F   H       + +EL 
Sbjct: 8   SRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELL 67

Query: 73  GFLRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGL 132
           G     +    + +   +    WD   A  F  ++++T G+G   P + GGK F + Y  
Sbjct: 68  GTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAA 127

Query: 133 VGCSSTILFFNLFLERLITIIA--YIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGW 190
           +G  +++         L+ +++      + H +    R AL Q                 
Sbjct: 128 LGLPASLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQA---------------- 171

Query: 191 KPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLV 244
                 V L L  AS  +   A  ++      S   ++YFCF + STIG  DL+
Sbjct: 172 ------VALGLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLL 219


>gi|32469495 potassium channel, subfamily K, member 18 [Homo
           sapiens]
          Length = 384

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 37/140 (26%), Positives = 56/140 (40%), Gaps = 9/140 (6%)

Query: 21  LLLAALIVLYLLGGAAVFSALE------LAHERQAKQRWEERLANFSRGHNLSRDELRGF 74
           L     +V Y L GA VFSA+E       A + + ++  EE     +    +  D  +  
Sbjct: 24  LCFLCFLVTYALVGAVVFSAIEDGQVLVAADDGEFEKFLEELCRILNCSETVVEDRKQDL 83

Query: 75  LRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVG 134
             H ++         N    W F  + +F  TV ST+G+G   P T  GK   + Y L G
Sbjct: 84  QGHLQKVKPQWF---NRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFG 140

Query: 135 CSSTILFFNLFLERLITIIA 154
                L      + L TI++
Sbjct: 141 IPLMFLVLTDTGDILATILS 160



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 4/71 (5%)

Query: 91  VRPRW----DFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSSTILFFNLFL 146
           + P W    DF  AFYF    ++TIGFG T        +F   Y +VG     + F L  
Sbjct: 300 ILPFWETQLDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEIVFIAFKLVQ 359

Query: 147 ERLITIIAYIM 157
            RLI I   +M
Sbjct: 360 NRLIDIYKNVM 370



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 37/164 (22%), Positives = 67/164 (40%), Gaps = 20/164 (12%)

Query: 222 WSYFDSLYFCFVAFSTIGFGDLVSSQNAHYESQGLYRFANFVFILMGVCCIYSLF----N 277
           WS+  SL+FC   FST+G+G +       Y    L ++   ++ L G+  ++ +     +
Sbjct: 101 WSFLSSLFFCCTVFSTVGYGYI-------YPVTRLGKYLCMLYALFGIPLMFLVLTDTGD 153

Query: 278 VISILIKQSLN------WILRKMDSGCCPQCQRGLLRSRRNVVMPGSVRNRCNISIETDG 331
           +++ ++  S N      +  R + S  CP   + L + + +         +  IS E   
Sbjct: 154 ILATILSTSYNRFRKFPFFTRPLLSKWCP---KSLFKKKPDPKPADEAVPQIIISAEELP 210

Query: 332 VAESDTDGRRLSGEMISMKDLLAANKASLAILQKQLSEMANGCP 375
             +  T   R S  M   +   A  K +   L  Q  E +N CP
Sbjct: 211 GPKLGTCPSRPSCSMELFERSHALEKQNTLQLPPQAMERSNSCP 254



 Score = 37.0 bits (84), Expect = 0.032
 Identities = 21/72 (29%), Positives = 38/72 (52%), Gaps = 7/72 (9%)

Query: 208 ISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHYESQGLYRFANFVFILM 267
           ISC A+ +        + ++ YFCFV  +TIGFGD V       E    + F + ++I++
Sbjct: 294 ISCAAAILPFWETQLDFENAFYFCFVTLTTIGFGDTV------LEHPNFFLFFS-IYIIV 346

Query: 268 GVCCIYSLFNVI 279
           G+  ++  F ++
Sbjct: 347 GMEIVFIAFKLV 358


>gi|41349443 potassium channel, subfamily T, member 2 [Homo sapiens]
          Length = 1135

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 22/48 (45%), Positives = 27/48 (56%), Gaps = 10/48 (20%)

Query: 206 ILISCCASAMYTPIEGWSY----------FDSLYFCFVAFSTIGFGDL 243
           ILIS     ++T I G  +          FDSLYFC V FST+GFGD+
Sbjct: 201 ILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTFSTVGFGDV 248



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 12/41 (29%), Positives = 22/41 (53%)

Query: 88  VDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLI 128
           ++ +  + +   + YF     ST+GFG  TP T   K+F++
Sbjct: 220 LERIGKKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVV 260


>gi|240255505 potassium channel, subfamily T, member 1 [Homo
           sapiens]
          Length = 1235

 Score = 37.7 bits (86), Expect = 0.019
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 3/50 (6%)

Query: 197 VMLILCTASILI---SCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDL 243
           V+++ CT   L+   +C    +    E  S   S YFC V FST+G+GD+
Sbjct: 271 VLILFCTLLCLVFTGTCGIQHLERAGENLSLLTSFYFCIVTFSTVGYGDV 320


>gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]
          Length = 438

 Score = 33.5 bits (75), Expect = 0.36
 Identities = 14/58 (24%), Positives = 30/58 (51%)

Query: 101 FYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSSTILFFNLFLERLITIIAYIMK 158
           FY +   + T+G+ ++  +   G I L  +  + C+   +  NLFL  ++  I+ ++K
Sbjct: 122 FYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVK 179


>gi|157074214 potassium channel, subfamily U, member 1 [Homo
           sapiens]
          Length = 1149

 Score = 32.7 bits (73), Expect = 0.61
 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 6/47 (12%)

Query: 223 SYFDSLYFCFVAFSTIGFGDLVSSQN------AHYESQGLYRFANFV 263
           SYF+S+Y      ST+GFGD+V+  +        +    L  FAN++
Sbjct: 262 SYFESIYLVMATTSTVGFGDVVAKTSLGRTFIMFFTLGSLILFANYI 308



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 4/55 (7%)

Query: 100 AFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSSTILFFNLFLERLITIIA 154
           + Y V    ST+GFG     T  G+ F++F+ L    S ILF N ++  ++ + A
Sbjct: 266 SIYLVMATTSTVGFGDVVAKTSLGRTFIMFFTL---GSLILFAN-YIPEMVELFA 316


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,007,819
Number of Sequences: 37866
Number of extensions: 559228
Number of successful extensions: 2145
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1969
Number of HSP's gapped (non-prelim): 137
length of query: 408
length of database: 18,247,518
effective HSP length: 105
effective length of query: 303
effective length of database: 14,271,588
effective search space: 4324291164
effective search space used: 4324291164
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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