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Search of human proteins with 16306525
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
(291 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16306525 cyclin B3 isoform 1 [Homo sapiens] 584 e-167
gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 450 e-127
gi|14327896 cyclin B1 [Homo sapiens] 126 2e-29
gi|4757930 cyclin B2 [Homo sapiens] 125 3e-29
gi|161377472 cyclin A1 isoform c [Homo sapiens] 119 2e-27
gi|161377470 cyclin A1 isoform c [Homo sapiens] 119 2e-27
gi|161377468 cyclin A1 isoform b [Homo sapiens] 119 2e-27
gi|4502611 cyclin A1 isoform a [Homo sapiens] 119 2e-27
gi|4502613 cyclin A [Homo sapiens] 102 3e-22
gi|118572588 cyclin F [Homo sapiens] 71 1e-12
gi|153791755 cyclin domain containing [Homo sapiens] 60 2e-09
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho... 60 2e-09
gi|17318565 cyclin E2 [Homo sapiens] 56 4e-08
gi|17318559 cyclin E1 isoform 1 [Homo sapiens] 54 1e-07
gi|17318561 cyclin E1 isoform 2 [Homo sapiens] 54 1e-07
gi|197276674 cyclin J isoform 1 [Homo sapiens] 52 5e-07
gi|16950655 cyclin D1 [Homo sapiens] 50 2e-06
gi|40805832 cyclin G1 [Homo sapiens] 50 2e-06
gi|4757934 cyclin G1 [Homo sapiens] 50 2e-06
gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 44 2e-04
gi|4502617 cyclin D2 [Homo sapiens] 44 2e-04
gi|40254889 cyclin J isoform 2 [Homo sapiens] 43 3e-04
gi|197276676 cyclin J isoform 3 [Homo sapiens] 43 4e-04
gi|89886237 cyclin I family, member 2 [Homo sapiens] 41 0.001
gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 40 0.002
gi|5802992 cyclin I [Homo sapiens] 40 0.002
gi|94680985 cyclin J-like [Homo sapiens] 38 0.009
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 33 0.23
gi|138175847 zinc finger protein 228 isoform 1 [Homo sapiens] 30 1.9
gi|138175821 zinc finger protein 228 isoform 2 [Homo sapiens] 30 1.9
>gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
Length = 291
Score = 584 bits (1506), Expect = e-167
Identities = 291/291 (100%), Positives = 291/291 (100%)
Query: 1 MLLPLPPQSSKPVPKKSQSSKIVPSHHDPSEKTGENCQTKISPSSLQESPSSLQGALKKR 60
MLLPLPPQSSKPVPKKSQSSKIVPSHHDPSEKTGENCQTKISPSSLQESPSSLQGALKKR
Sbjct: 1 MLLPLPPQSSKPVPKKSQSSKIVPSHHDPSEKTGENCQTKISPSSLQESPSSLQGALKKR 60
Query: 61 SAFEDLTNVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPR 120
SAFEDLTNVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPR
Sbjct: 61 SAFEDLTNVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPR 120
Query: 121 VDDFVYICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRY 180
VDDFVYICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRY
Sbjct: 121 VDDFVYICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRY 180
Query: 181 ICEMTLQEYHYVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNK 240
ICEMTLQEYHYVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNK
Sbjct: 181 ICEMTLQEYHYVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNK 240
Query: 241 LLTFSSYDSLKAVYYKYSHPVFFEVAKIPALDMLKLEEILNCDCEAQGLVL 291
LLTFSSYDSLKAVYYKYSHPVFFEVAKIPALDMLKLEEILNCDCEAQGLVL
Sbjct: 241 LLTFSSYDSLKAVYYKYSHPVFFEVAKIPALDMLKLEEILNCDCEAQGLVL 291
>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
Length = 1395
Score = 450 bits (1158), Expect = e-127
Identities = 223/223 (100%), Positives = 223/223 (100%)
Query: 69 VSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYIC 128
VSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYIC
Sbjct: 1173 VSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYIC 1232
Query: 129 DDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQE 188
DDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQE
Sbjct: 1233 DDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQE 1292
Query: 189 YHYVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSSYD 248
YHYVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSSYD
Sbjct: 1293 YHYVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSSYD 1352
Query: 249 SLKAVYYKYSHPVFFEVAKIPALDMLKLEEILNCDCEAQGLVL 291
SLKAVYYKYSHPVFFEVAKIPALDMLKLEEILNCDCEAQGLVL
Sbjct: 1353 SLKAVYYKYSHPVFFEVAKIPALDMLKLEEILNCDCEAQGLVL 1395
Score = 140 bits (352), Expect = 2e-33
Identities = 69/70 (98%), Positives = 69/70 (98%)
Query: 1 MLLPLPPQSSKPVPKKSQSSKIVPSHHDPSEKTGENCQTKISPSSLQESPSSLQGALKKR 60
MLLPLPPQSSKPVPKKSQSSKIVPSHHDPSEKTGENCQTKISPSSLQESPSSLQGALKKR
Sbjct: 1 MLLPLPPQSSKPVPKKSQSSKIVPSHHDPSEKTGENCQTKISPSSLQESPSSLQGALKKR 60
Query: 61 SAFEDLTNVS 70
SAFEDLTN S
Sbjct: 61 SAFEDLTNAS 70
>gi|14327896 cyclin B1 [Homo sapiens]
Length = 433
Score = 126 bits (317), Expect = 2e-29
Identities = 64/213 (30%), Positives = 117/213 (54%), Gaps = 2/213 (0%)
Query: 69 VSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYIC 128
+ F + ET+Y+ V ++D ++ K LQL+G TA IA+K+EE P + DF ++
Sbjct: 214 MKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVT 273
Query: 129 DDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQE 188
D+ Y + ++ ME+ IL L + P+ HFLRR ++ +++ TL++Y+ E+T+ +
Sbjct: 274 DNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLD 333
Query: 189 YHYVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSSYD 248
Y V S++AA + LAL + G W P L+HY Y+ L P+++ L K + +
Sbjct: 334 YDMVHFPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQG 393
Query: 249 SLK--AVYYKYSHPVFFEVAKIPALDMLKLEEI 279
K V KY+ +++ +P L+ ++++
Sbjct: 394 LTKHMTVKNKYATSKHAKISTLPQLNSALVQDL 426
>gi|4757930 cyclin B2 [Homo sapiens]
Length = 398
Score = 125 bits (315), Expect = 3e-29
Identities = 69/211 (32%), Positives = 125/211 (59%), Gaps = 2/211 (0%)
Query: 71 FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 130
F + ETLY+ V ++D +L + KLQL+G TA ++A+K+EE SP ++DFVYI D+
Sbjct: 180 FRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDN 239
Query: 131 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYH 190
Y S++ ME IL LK ++ P+ HFLRR ++ +++ TL++Y+ E+TL +Y
Sbjct: 240 AYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYD 299
Query: 191 YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSSYDSL 250
V SK+AAA+ L+ + G W ++Y+GY+ +E+ +++ + K + + +
Sbjct: 300 MVHYHPSKVAAAASCLSQKVLGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNENLT 359
Query: 251 K--AVYYKYSHPVFFEVAKIPALDMLKLEEI 279
K A+ KY+ +++ IP L+ ++++
Sbjct: 360 KFIAIKNKYASSKLLKISMIPQLNSKAVKDL 390
>gi|161377472 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 119 bits (299), Expect = 2e-27
Identities = 67/188 (35%), Positives = 109/188 (57%), Gaps = 1/188 (0%)
Query: 71 FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 130
+++ ETLYLAV +D +L + KLQL+G A ++A+K+EE P VD+FVYI DD
Sbjct: 214 YKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDD 273
Query: 131 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYH 190
Y + ++L ME +L VL D+ +P FL +Y R ++T L++Y+ E++L E
Sbjct: 274 TYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEAD 333
Query: 191 -YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSSYDS 249
+++ S +AAA+ LA Y +W L ++GYS+SE+ P + +L+K +
Sbjct: 334 PFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRP 393
Query: 250 LKAVYYKY 257
+A+ KY
Sbjct: 394 QQAIREKY 401
>gi|161377470 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 119 bits (299), Expect = 2e-27
Identities = 67/188 (35%), Positives = 109/188 (57%), Gaps = 1/188 (0%)
Query: 71 FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 130
+++ ETLYLAV +D +L + KLQL+G A ++A+K+EE P VD+FVYI DD
Sbjct: 214 YKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDD 273
Query: 131 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYH 190
Y + ++L ME +L VL D+ +P FL +Y R ++T L++Y+ E++L E
Sbjct: 274 TYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEAD 333
Query: 191 -YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSSYDS 249
+++ S +AAA+ LA Y +W L ++GYS+SE+ P + +L+K +
Sbjct: 334 PFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRP 393
Query: 250 LKAVYYKY 257
+A+ KY
Sbjct: 394 QQAIREKY 401
>gi|161377468 cyclin A1 isoform b [Homo sapiens]
Length = 464
Score = 119 bits (299), Expect = 2e-27
Identities = 67/188 (35%), Positives = 109/188 (57%), Gaps = 1/188 (0%)
Query: 71 FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 130
+++ ETLYLAV +D +L + KLQL+G A ++A+K+EE P VD+FVYI DD
Sbjct: 257 YKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDD 316
Query: 131 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYH 190
Y + ++L ME +L VL D+ +P FL +Y R ++T L++Y+ E++L E
Sbjct: 317 TYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEAD 376
Query: 191 -YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSSYDS 249
+++ S +AAA+ LA Y +W L ++GYS+SE+ P + +L+K +
Sbjct: 377 PFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRP 436
Query: 250 LKAVYYKY 257
+A+ KY
Sbjct: 437 QQAIREKY 444
>gi|4502611 cyclin A1 isoform a [Homo sapiens]
Length = 465
Score = 119 bits (299), Expect = 2e-27
Identities = 67/188 (35%), Positives = 109/188 (57%), Gaps = 1/188 (0%)
Query: 71 FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 130
+++ ETLYLAV +D +L + KLQL+G A ++A+K+EE P VD+FVYI DD
Sbjct: 258 YKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDD 317
Query: 131 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYH 190
Y + ++L ME +L VL D+ +P FL +Y R ++T L++Y+ E++L E
Sbjct: 318 TYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEAD 377
Query: 191 -YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSSYDS 249
+++ S +AAA+ LA Y +W L ++GYS+SE+ P + +L+K +
Sbjct: 378 PFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRP 437
Query: 250 LKAVYYKY 257
+A+ KY
Sbjct: 438 QQAIREKY 445
>gi|4502613 cyclin A [Homo sapiens]
Length = 432
Score = 102 bits (255), Expect = 3e-22
Identities = 66/210 (31%), Positives = 112/210 (53%), Gaps = 6/210 (2%)
Query: 71 FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 130
+++ +ETL+LAV +D +L + KLQL+G A ++A+KFEE P V +FVYI DD
Sbjct: 225 YKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDD 284
Query: 131 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIH---TNMKTLTLSRYICEMTLQ 187
Y + +VL ME +L VL D+ P FL +Y +H N K +L+ ++ E++L
Sbjct: 285 TYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQY--FLHQQPANCKVESLAMFLGELSLI 342
Query: 188 EYH-YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSS 246
+ Y++ S +A A+ LALY W L +GY++ L P + L++ +
Sbjct: 343 DADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAP 402
Query: 247 YDSLKAVYYKYSHPVFFEVAKIPALDMLKL 276
+ +++ KY + + V+ + + L L
Sbjct: 403 QHAQQSIREKYKNSKYHGVSLLNPPETLNL 432
>gi|118572588 cyclin F [Homo sapiens]
Length = 786
Score = 71.2 bits (173), Expect = 1e-12
Identities = 46/170 (27%), Positives = 84/170 (49%), Gaps = 1/170 (0%)
Query: 72 EMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDN 131
+ T L+L V+ VD YL + + + +LQLLG +I +F + + V++ D+
Sbjct: 325 DFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKEILTIREAVWLTDNT 384
Query: 132 YQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYHY 191
Y+ +++ M I++ L+ I +P + + ++T L ++CE++L
Sbjct: 385 YKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTSL 444
Query: 192 VQEKASKLAAASLLLA-LYMKKLGYWVPFLEHYSGYSISELHPLVRQLNK 240
++LAAA+LLLA L + W L +G+S +L P V L+K
Sbjct: 445 SAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHK 494
>gi|153791755 cyclin domain containing [Homo sapiens]
Length = 350
Score = 60.5 bits (145), Expect = 2e-09
Identities = 39/145 (26%), Positives = 66/145 (45%), Gaps = 8/145 (5%)
Query: 71 FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 130
F ++ E+L L V +D +L D QLLG T+ +IA K E + PRV + +C
Sbjct: 147 FGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCG 206
Query: 131 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARC--------IHTNMKTLTLSRYIC 182
+ R ++ ++E +L+ L + P FL + ++ L+R +
Sbjct: 207 AFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVA 266
Query: 183 EMTLQEYHYVQEKASKLAAASLLLA 207
E++L +Y + S LA L LA
Sbjct: 267 ELSLADYAFTSYSPSLLAICCLALA 291
>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
sapiens]
Length = 307
Score = 60.1 bits (144), Expect = 2e-09
Identities = 42/132 (31%), Positives = 65/132 (49%)
Query: 76 ETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRS 135
+TLYLAV L+D YL + +LQLLG +A K EE P + D++ R+
Sbjct: 127 DTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLCLLSADSFSRA 186
Query: 136 EVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYHYVQEK 195
E+L E IL+ L ++ P L A ++ + + L+ Y E++L E +
Sbjct: 187 ELLRAERRILSRLDFRLHHPGPLLCLGLLAALAGSSPQVMLLATYFLELSLLEAEAAGWE 246
Query: 196 ASKLAAASLLLA 207
+ AAA+L LA
Sbjct: 247 PGRRAAAALSLA 258
>gi|17318565 cyclin E2 [Homo sapiens]
Length = 404
Score = 55.8 bits (133), Expect = 4e-08
Identities = 28/83 (33%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
Query: 71 FEMTHETLYLAVKLVDLYLM-KAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICD 129
+ + ET YLA D +++ + K+ LQL+G T+ IA+K EE +P++ +F Y+ D
Sbjct: 156 YTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTD 215
Query: 130 DNYQRSEVLSMEINILNVLKCDI 152
++L ME+ IL LK ++
Sbjct: 216 GACSEEDILRMELIILKALKWEL 238
>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
Length = 410
Score = 54.3 bits (129), Expect = 1e-07
Identities = 35/119 (29%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Query: 71 FEMTHETLYLAVKLVDLYLM-KAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICD 129
+++ ET YLA D Y+ + K LQL+G ++ IAAK EE P++ F Y+ D
Sbjct: 159 YKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTD 218
Query: 130 DNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTN-MKTLTLSRYICEMTLQ 187
E+L+ME+ I+ LK ++ +L Y + + N + + L +Y ++ +Q
Sbjct: 219 GACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQ 277
>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
Length = 395
Score = 54.3 bits (129), Expect = 1e-07
Identities = 35/119 (29%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Query: 71 FEMTHETLYLAVKLVDLYLM-KAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICD 129
+++ ET YLA D Y+ + K LQL+G ++ IAAK EE P++ F Y+ D
Sbjct: 144 YKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTD 203
Query: 130 DNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTN-MKTLTLSRYICEMTLQ 187
E+L+ME+ I+ LK ++ +L Y + + N + + L +Y ++ +Q
Sbjct: 204 GACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQ 262
>gi|197276674 cyclin J isoform 1 [Homo sapiens]
Length = 383
Score = 52.4 bits (124), Expect = 5e-07
Identities = 53/223 (23%), Positives = 97/223 (43%), Gaps = 32/223 (14%)
Query: 43 PSSLQESPSSLQGALKKRSAFEDLTNV---SFEMTHETLYLAVKLVDLYLMKAVCKKDKL 99
PS +SP L R F DL + F + +LAV L+DL++ + +L
Sbjct: 28 PSYKGQSPQ-----LSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQL 82
Query: 100 QLLGATAFMIAAKFEEHNS--PRVDDFVYI-CDDNYQ----RSEVLSMEINILNVLKCDI 152
L+ + ++A+KFEE P+++ + C N + +L ME+ +L + ++
Sbjct: 83 HLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNL 142
Query: 153 NIPIAYHFLRRY-ARCIH---------------TNMKTLTLSRYICEMTLQEYHYVQEKA 196
+P A HF+ Y + +H T + + Y E++LQ+Y ++
Sbjct: 143 CLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEVSLQDYAFLNYAP 202
Query: 197 SKLAAASLLLALYMKKLG-YWVPFLEHYSGYSISELHPLVRQL 238
S +AAA + + + +L W L + YS L + +L
Sbjct: 203 SLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 245
>gi|16950655 cyclin D1 [Homo sapiens]
Length = 295
Score = 50.1 bits (118), Expect = 2e-06
Identities = 37/152 (24%), Positives = 67/152 (44%), Gaps = 4/152 (2%)
Query: 76 ETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRS 135
E LA+ +D +L KK +LQLLGAT +A+K +E + D++ +
Sbjct: 76 EVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPE 135
Query: 136 EVLSMEINILNVLKCDINIPIAY----HFLRRYARCIHTNMKTLTLSRYICEMTLQEYHY 191
E+L ME+ ++N LK ++ + HFL + ++ + + +
Sbjct: 136 ELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKF 195
Query: 192 VQEKASKLAAASLLLALYMKKLGYWVPFLEHY 223
+ S +AA S++ A+ L FL +Y
Sbjct: 196 ISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYY 227
>gi|40805832 cyclin G1 [Homo sapiens]
Length = 295
Score = 50.1 bits (118), Expect = 2e-06
Identities = 63/262 (24%), Positives = 110/262 (41%), Gaps = 41/262 (15%)
Query: 37 CQTKISPSSLQESP--SSLQGALKKRS-AFEDLTNVS--FEMTHETLYLAVKLVDLYLMK 91
CQ K+ L ES + L+ + R +DL +++ F ET LAV L+D +L K
Sbjct: 27 CQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSK 86
Query: 92 AVCKKDKLQLLGATAFMIAAKF--EEHNSPRVDDFVYICDDNYQRSEVLSMEINILNVLK 149
+ L +G + F +A K EE N P D + I + S+++ ME +L +
Sbjct: 87 MKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVC 146
Query: 150 CDINIPIAYHFLRRYARCIHTNM---KTLTLSRYICEMTLQEYH----YVQEKASKLAAA 202
+ A+ FL+ Y + N+ + +++ E L+ H + + K S LA +
Sbjct: 147 WKVKATTAFQFLQLYYSLLQENLPLERRNSINFERLEAQLKACHCRIIFSKAKPSVLALS 206
Query: 203 SLLLALYMKK---------------------LGYWVPF----LEHYSGYSISELHPLVRQ 237
+ L + +K L +W L YS S+ P V++
Sbjct: 207 IIALEIQAQKCVELTEGIECLQKHSKINGRDLTFWQELVSKCLTEYSSNKCSK--PNVQK 264
Query: 238 LNKLLTFSSYDSLKAVYYKYSH 259
L +++ + LK YY+ +H
Sbjct: 265 LKWIVSGRTARQLKHSYYRITH 286
>gi|4757934 cyclin G1 [Homo sapiens]
Length = 295
Score = 50.1 bits (118), Expect = 2e-06
Identities = 63/262 (24%), Positives = 110/262 (41%), Gaps = 41/262 (15%)
Query: 37 CQTKISPSSLQESP--SSLQGALKKRS-AFEDLTNVS--FEMTHETLYLAVKLVDLYLMK 91
CQ K+ L ES + L+ + R +DL +++ F ET LAV L+D +L K
Sbjct: 27 CQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSK 86
Query: 92 AVCKKDKLQLLGATAFMIAAKF--EEHNSPRVDDFVYICDDNYQRSEVLSMEINILNVLK 149
+ L +G + F +A K EE N P D + I + S+++ ME +L +
Sbjct: 87 MKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVC 146
Query: 150 CDINIPIAYHFLRRYARCIHTNM---KTLTLSRYICEMTLQEYH----YVQEKASKLAAA 202
+ A+ FL+ Y + N+ + +++ E L+ H + + K S LA +
Sbjct: 147 WKVKATTAFQFLQLYYSLLQENLPLERRNSINFERLEAQLKACHCRIIFSKAKPSVLALS 206
Query: 203 SLLLALYMKK---------------------LGYWVPF----LEHYSGYSISELHPLVRQ 237
+ L + +K L +W L YS S+ P V++
Sbjct: 207 IIALEIQAQKCVELTEGIECLQKHSKINGRDLTFWQELVSKCLTEYSSNKCSK--PNVQK 264
Query: 238 LNKLLTFSSYDSLKAVYYKYSH 259
L +++ + LK YY+ +H
Sbjct: 265 LKWIVSGRTARQLKHSYYRITH 286
>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
Length = 292
Score = 43.9 bits (102), Expect = 2e-04
Identities = 26/86 (30%), Positives = 41/86 (47%)
Query: 76 ETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRS 135
E LA+ +D YL +K +LQLLGA ++A+K E ++ D
Sbjct: 76 EVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPR 135
Query: 136 EVLSMEINILNVLKCDINIPIAYHFL 161
++ E+ +L LK D+ IA+ FL
Sbjct: 136 QLRDWEVLVLGKLKWDLAAVIAHDFL 161
>gi|4502617 cyclin D2 [Homo sapiens]
Length = 289
Score = 43.5 bits (101), Expect = 2e-04
Identities = 27/104 (25%), Positives = 48/104 (46%)
Query: 76 ETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRS 135
E LA+ +D +L K LQLLGA +A+K +E + + D++ +
Sbjct: 75 EVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQ 134
Query: 136 EVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSR 179
E+L E+ +L LK ++ + F+ R + + L+L R
Sbjct: 135 ELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIR 178
>gi|40254889 cyclin J isoform 2 [Homo sapiens]
Length = 372
Score = 43.1 bits (100), Expect = 3e-04
Identities = 46/212 (21%), Positives = 86/212 (40%), Gaps = 21/212 (9%)
Query: 43 PSSLQESPSSLQGALKKRSAFEDLTNV---SFEMTHETLYLAVKLVDLYLMKAVCKKDKL 99
PS +SP L R F DL + F + +LAV L+DL++ + +L
Sbjct: 28 PSYKGQSPQ-----LSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQL 82
Query: 100 QLLGATAFMIAAKFEEHNS--PRVDDFVYI-CDDNYQ----RSEVLSMEINILNVLKCDI 152
L+ + ++A+KFEE P+++ + C N + +L ME+ +L + ++
Sbjct: 83 HLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNL 142
Query: 153 NIPIAYHFLRRY------ARCIHTNMKTLTLSRYICEMTLQEYHYVQEKASKLAAASLLL 206
+P A HF+ Y +H + L + M ++++ AA
Sbjct: 143 CLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEVSLQVAAACVASS 202
Query: 207 ALYMKKLGYWVPFLEHYSGYSISELHPLVRQL 238
+ ++ W L + YS L + +L
Sbjct: 203 RIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 234
>gi|197276676 cyclin J isoform 3 [Homo sapiens]
Length = 371
Score = 42.7 bits (99), Expect = 4e-04
Identities = 35/132 (26%), Positives = 62/132 (46%), Gaps = 15/132 (11%)
Query: 43 PSSLQESPSSLQGALKKRSAFEDLTNV---SFEMTHETLYLAVKLVDLYLMKAVCKKDKL 99
PS +SP L R F DL + F + +LAV L+DL++ + +L
Sbjct: 28 PSYKGQSPQ-----LSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQL 82
Query: 100 QLLGATAFMIAAKFEEHNS--PRVDDFVYI-CDDNYQ----RSEVLSMEINILNVLKCDI 152
L+ + ++A+KFEE P+++ + C N + +L ME+ +L + ++
Sbjct: 83 HLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNL 142
Query: 153 NIPIAYHFLRRY 164
+P A HF+ Y
Sbjct: 143 CLPTAAHFIEYY 154
>gi|89886237 cyclin I family, member 2 [Homo sapiens]
Length = 369
Score = 40.8 bits (94), Expect = 0.001
Identities = 41/164 (25%), Positives = 66/164 (40%), Gaps = 15/164 (9%)
Query: 70 SFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNS--PRVDDFVYI 127
+F + T LA+ + L+ K+ L T+ +AAK E P+V DF
Sbjct: 163 TFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQVKDFTKH 222
Query: 128 CDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTN-------MKTLTLSRY 180
+Y +E+L ME+ IL+ L D+ I FL + + + + S +
Sbjct: 223 YGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELLPQRNPSLH 282
Query: 181 ICEMTLQEYH------YVQEKASKLAAASLLLALYMKKLGYWVP 218
+ +T Q H +Q K S LA + L L G+ P
Sbjct: 283 VASLTRQLQHCMAGHQLLQFKGSTLALVIITLELERLMPGWCAP 326
>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
Length = 211
Score = 40.0 bits (92), Expect = 0.002
Identities = 23/77 (29%), Positives = 37/77 (48%)
Query: 85 VDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRSEVLSMEINI 144
+D YL +K +LQLLGA ++A+K E ++ D ++ E+ +
Sbjct: 4 LDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLV 63
Query: 145 LNVLKCDINIPIAYHFL 161
L LK D+ IA+ FL
Sbjct: 64 LGKLKWDLAAVIAHDFL 80
>gi|5802992 cyclin I [Homo sapiens]
Length = 377
Score = 40.0 bits (92), Expect = 0.002
Identities = 48/187 (25%), Positives = 83/187 (44%), Gaps = 23/187 (12%)
Query: 43 PSSLQESPSSLQGALKKRSAFEDLTNVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLL 102
PS+ SPS ++ + + F + ET LA L+D +L L +
Sbjct: 35 PSNQNVSPSQRDEVIQWLAKLK----YQFNLYPETFALASSLLDRFLATVKAHPKYLSCI 90
Query: 103 GATAFMIAAKFEEHNSPRVDDFVYICDDNY---QRSEVLSMEINILNVLKCDINIPIAYH 159
+ F +AAK E + R+ + D++ SE+L ME IL+ L D++
Sbjct: 91 AISCFFLAAKTVEEDE-RIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLD 149
Query: 160 FLRRY-ARCIHT------NMKTLTLSRYICEMTLQEYH------YVQEKASKLAAASLLL 206
FL + A + T ++ L+ S+++ +T Q H +Q + S LA A ++
Sbjct: 150 FLHIFHAIAVSTRPQLLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQFRGSMLALA--MV 207
Query: 207 ALYMKKL 213
+L M+KL
Sbjct: 208 SLEMEKL 214
>gi|94680985 cyclin J-like [Homo sapiens]
Length = 435
Score = 38.1 bits (87), Expect = 0.009
Identities = 36/147 (24%), Positives = 62/147 (42%), Gaps = 25/147 (17%)
Query: 112 KFEEHNSPRVDDFVYICDDNYQ--RSEVLSMEINILNVLKCDINIPIAYHFLRRY----- 164
K E+ NS R+ + N+ + E+LS E+ +L ++ +P HFL Y
Sbjct: 153 KLEQINSTRI-----LSSQNFTLTKKELLSTELLLLEAFSWNLCLPTPAHFLDYYLLASV 207
Query: 165 -----------ARCIHTNMKTLT-LSRYICEMTLQEYHYVQEKASKLAAASLLLALYMKK 212
C + L + Y E+TLQ++ + + + S +AAA + + +
Sbjct: 208 SQKDHHCHTWPTTCPRKTKECLKEYAHYFLEVTLQDHIFYKFQPSVVAAACVGASRICLQ 267
Query: 213 LG-YWVPFLEHYSGYSISELHPLVRQL 238
L YW L+ S YS+ L + L
Sbjct: 268 LSPYWTRDLQRISSYSLEHLSTCIEIL 294
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 33.5 bits (75), Expect = 0.23
Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Query: 6 PPQSSKPVPKKSQSSKIVPSHHDPSEKTGENCQTKISPSSLQESPSSLQGALKKRSAFED 65
PP P P+ ++ +++ HH P + S L+E+PS L + S F+
Sbjct: 1023 PPGQQPPPPQPAKPQQVIQHHHSPRHHKSD----PYSTGHLREAPSPLMIHSPQMSQFQS 1078
Query: 66 LTNVS 70
LT+ S
Sbjct: 1079 LTHQS 1083
>gi|138175847 zinc finger protein 228 isoform 1 [Homo sapiens]
Length = 913
Score = 30.4 bits (67), Expect = 1.9
Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
Query: 126 YICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMT 185
+IC N + ME N N +C +A HF + + +HT K RY+C +
Sbjct: 424 FICSSNLDIQHRVHMEENSYNSEECGNGFSLASHF--QDLQIVHT--KEQPYKRYVCSNS 479
Query: 186 LQEYHYVQ 193
Y+Q
Sbjct: 480 FSHNLYLQ 487
>gi|138175821 zinc finger protein 228 isoform 2 [Homo sapiens]
Length = 907
Score = 30.4 bits (67), Expect = 1.9
Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
Query: 126 YICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMT 185
+IC N + ME N N +C +A HF + + +HT K RY+C +
Sbjct: 418 FICSSNLDIQHRVHMEENSYNSEECGNGFSLASHF--QDLQIVHT--KEQPYKRYVCSNS 473
Query: 186 LQEYHYVQ 193
Y+Q
Sbjct: 474 FSHNLYLQ 481
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,307,355
Number of Sequences: 37866
Number of extensions: 423195
Number of successful extensions: 1774
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 1710
Number of HSP's gapped (non-prelim): 80
length of query: 291
length of database: 18,247,518
effective HSP length: 101
effective length of query: 190
effective length of database: 14,423,052
effective search space: 2740379880
effective search space used: 2740379880
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.