Guide to the Human Genome
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Search of human proteins with 162417973

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|162417973 claudin 22 [Homo sapiens]
         (220 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|162417973 claudin 22 [Homo sapiens]                                457   e-129
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]                399   e-112
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]                398   e-111
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]                398   e-111
gi|157820127 claudin-like [Homo sapiens]                              230   6e-61
gi|153792186 claudin 7 [Homo sapiens]                                 127   1e-29
gi|153792768 claudin 6 [Homo sapiens]                                 125   4e-29
gi|11141861 claudin 9 [Homo sapiens]                                  120   1e-27
gi|10863887 claudin 1 [Homo sapiens]                                  120   1e-27
gi|40788011 claudin 8 [Homo sapiens]                                  120   1e-27
gi|4502877 claudin 4 [Homo sapiens]                                   117   8e-27
gi|183979973 claudin 19 isoform a [Homo sapiens]                      114   5e-26
gi|183979975 claudin 19 isoform b [Homo sapiens]                      114   5e-26
gi|195947374 claudin 5 [Homo sapiens]                                 113   1e-25
gi|195947372 claudin 5 [Homo sapiens]                                 113   1e-25
gi|4502875 claudin 3 [Homo sapiens]                                   112   2e-25
gi|7705961 claudin 18 isoform 1 [Homo sapiens]                        107   8e-24
gi|6912316 claudin 17 [Homo sapiens]                                  107   8e-24
gi|225703142 claudin 14 [Homo sapiens]                                107   1e-23
gi|21536294 claudin 14 [Homo sapiens]                                 107   1e-23
gi|225703138 claudin 14 [Homo sapiens]                                107   1e-23
gi|6912314 claudin 14 [Homo sapiens]                                  107   1e-23
gi|225703140 claudin 14 [Homo sapiens]                                107   1e-23
gi|50345279 claudin 18 isoform 2 [Homo sapiens]                       105   3e-23
gi|9966781 claudin 2 [Homo sapiens]                                    99   4e-21
gi|5921465 claudin 10 isoform b [Homo sapiens]                         99   4e-21
gi|7656981 claudin 15 [Homo sapiens]                                   91   6e-19
gi|47716519 claudin 20 [Homo sapiens]                                  80   2e-15
gi|33598916 claudin 10 isoform a [Homo sapiens]                        73   2e-13
gi|10938016 claudin 11 [Homo sapiens]                                  66   3e-11

>gi|162417973 claudin 22 [Homo sapiens]
          Length = 220

 Score =  457 bits (1177), Expect = e-129
 Identities = 220/220 (100%), Positives = 220/220 (100%)

Query: 1   MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60
           MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV
Sbjct: 1   MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60

Query: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120
           GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI
Sbjct: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120

Query: 121 LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180
           LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG
Sbjct: 121 LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180

Query: 181 CLLHCAACSSHAPLASGHYAVAQTQDHHQELETRNTNLKH 220
           CLLHCAACSSHAPLASGHYAVAQTQDHHQELETRNTNLKH
Sbjct: 181 CLLHCAACSSHAPLASGHYAVAQTQDHHQELETRNTNLKH 220


>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score =  399 bits (1026), Expect = e-112
 Identities = 192/212 (90%), Positives = 198/212 (93%)

Query: 1   MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60
           MAL+FRT  Q  G+ LSLLGW+LS +T YLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV
Sbjct: 1   MALIFRTAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60

Query: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120
           GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI
Sbjct: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120

Query: 121 LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180
           LGGILSWASG+TALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG
Sbjct: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180

Query: 181 CLLHCAACSSHAPLASGHYAVAQTQDHHQELE 212
           CLL+CAACSSHAPLA GHYAVAQ Q     LE
Sbjct: 181 CLLNCAACSSHAPLALGHYAVAQMQTQCPYLE 212


>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score =  398 bits (1022), Expect = e-111
 Identities = 191/212 (90%), Positives = 197/212 (92%)

Query: 1   MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60
           MAL+FRT  Q  G+ LS LGW+LS +T YLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV
Sbjct: 1   MALIFRTAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60

Query: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120
           GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI
Sbjct: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120

Query: 121 LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180
           LGGILSWASG+TALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG
Sbjct: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180

Query: 181 CLLHCAACSSHAPLASGHYAVAQTQDHHQELE 212
           CLL+CAACSSHAPLA GHYAVAQ Q     LE
Sbjct: 181 CLLNCAACSSHAPLALGHYAVAQMQTQCPYLE 212


>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score =  398 bits (1022), Expect = e-111
 Identities = 191/212 (90%), Positives = 197/212 (92%)

Query: 1   MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60
           MAL+FRT  Q  G+ LS LGW+LS +T YLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV
Sbjct: 1   MALIFRTAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60

Query: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120
           GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI
Sbjct: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120

Query: 121 LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180
           LGGILSWASG+TALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG
Sbjct: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180

Query: 181 CLLHCAACSSHAPLASGHYAVAQTQDHHQELE 212
           CLL+CAACSSHAPLA GHYAVAQ Q     LE
Sbjct: 181 CLLNCAACSSHAPLALGHYAVAQMQTQCPYLE 212


>gi|157820127 claudin-like [Homo sapiens]
          Length = 229

 Score =  230 bits (587), Expect = 6e-61
 Identities = 108/188 (57%), Positives = 136/188 (72%)

Query: 1   MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60
           MA  FR   QL G+ LSLLGWV SC+T  LP WK LNL+LNEME W MG+W+ CV +EEV
Sbjct: 1   MAWSFRAKVQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWIMGIWEVCVDREEV 60

Query: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120
              CK F+SFL+LP EL+V+RILM  S+GLG LGLL+  FG +C +    +   KRRL +
Sbjct: 61  ATVCKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGL 120

Query: 121 LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180
           LG  L  ++  T L+PVSWVAH T+Q+FWD+++PD +PRWEFG AL+LGW AG+ L LGG
Sbjct: 121 LGRTLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGG 180

Query: 181 CLLHCAAC 188
            LL  +AC
Sbjct: 181 LLLIFSAC 188


>gi|153792186 claudin 7 [Homo sapiens]
          Length = 211

 Score =  127 bits (318), Expect = 1e-29
 Identities = 68/180 (37%), Positives = 102/180 (56%), Gaps = 4/180 (2%)

Query: 10  QLAGVSLSLLGWVLSCLTNYLPHWKNLNL---DLNEMENWTMGLWQTCVIQEEVGMQCKD 66
           QL G S++LLGWV       +P W+  +    ++   +    GLW  CV Q    M CK 
Sbjct: 7   QLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSCKM 66

Query: 67  FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
           +DS LAL A L+ +R LM +S  LGFL + V+  G+ C R G   +  K R+ + GGI+ 
Sbjct: 67  YDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGGIIF 126

Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186
             +G+ ALV  SW  H+ V +F++  +P  + ++EFG A+F+GW     ++LGG LL C+
Sbjct: 127 IVAGLAALVACSWYGHQIVTDFYNPLIPTNI-KYEFGPAIFIGWAGSALVILGGALLSCS 185


>gi|153792768 claudin 6 [Homo sapiens]
          Length = 220

 Score =  125 bits (313), Expect = 4e-29
 Identities = 77/193 (39%), Positives = 106/193 (54%), Gaps = 6/193 (3%)

Query: 10  QLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTM---GLWQTCVIQEEVGMQCKD 66
           Q+ GV L+LLGWV   ++  LP WK      N +    +   GLW +CV+Q    MQCK 
Sbjct: 7   QILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKV 66

Query: 67  FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
           +DS LALP +L+ +R L  ++  +   GLLV   G  C    E ++D K RL++  GI+ 
Sbjct: 67  YDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVE-EKDSKARLVLTSGIVF 125

Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186
             SGV  L+PV W AH  +++F++  V +   R E G +L+LGW A   LLLGG LL C 
Sbjct: 126 VISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKR-ELGASLYLGWAASGLLLLGGGLL-CC 183

Query: 187 ACSSHAPLASGHY 199
            C S       HY
Sbjct: 184 TCPSGGSQGPSHY 196


>gi|11141861 claudin 9 [Homo sapiens]
          Length = 217

 Score =  120 bits (300), Expect = 1e-27
 Identities = 68/182 (37%), Positives = 106/182 (58%), Gaps = 5/182 (2%)

Query: 7   TVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTM---GLWQTCVIQEEVGMQ 63
           T  +L G++L++LGW+ + ++  LP WK      N +    +   GLW +CV+Q    MQ
Sbjct: 4   TGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQ 63

Query: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
           CK +DS LALP +L+ +R L  ++  L  LGLLV+  G  C    E +   K R+++  G
Sbjct: 64  CKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDE-GAKARIVLTAG 122

Query: 124 ILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
           ++   +G+  L+PV W AH  +Q+F++  V + + R E G +L+LGW A   L+LGG LL
Sbjct: 123 VILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKR-ELGASLYLGWAAAALLMLGGGLL 181

Query: 184 HC 185
            C
Sbjct: 182 CC 183


>gi|10863887 claudin 1 [Homo sapiens]
          Length = 211

 Score =  120 bits (300), Expect = 1e-27
 Identities = 65/180 (36%), Positives = 100/180 (55%), Gaps = 4/180 (2%)

Query: 10  QLAGVSLSLLGWVLSCLTNYLPHWKNLNL---DLNEMENWTMGLWQTCVIQEEVGMQCKD 66
           QL G  L+ LGW+ + ++  LP W+  +    ++   +    GLW +CV Q    +QCK 
Sbjct: 7   QLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCKV 66

Query: 67  FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
           FDS L L + L+ +R LM +   LG + + V+  G+ C++  E     K R+ ++GG + 
Sbjct: 67  FDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAIF 126

Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186
             +G+  LV  +W  ++ VQEF+D   P    R+EFG+ALF GW A    LLGG LL C+
Sbjct: 127 LLAGLAILVATAWYGNRIVQEFYDPMTP-VNARYEFGQALFTGWAAASLCLLGGALLCCS 185


>gi|40788011 claudin 8 [Homo sapiens]
          Length = 225

 Score =  120 bits (300), Expect = 1e-27
 Identities = 62/182 (34%), Positives = 103/182 (56%), Gaps = 4/182 (2%)

Query: 10  QLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEM---ENWTMGLWQTCVIQEEVGMQCKD 66
           ++AG+ L  +G V +     +P W+      N +   EN+  GLW  CV Q  + MQCK 
Sbjct: 7   EIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANIRMQCKI 66

Query: 67  FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
           +DS LAL  +L+ +R LM  ++ + FL  +++  G+ C R       +K  +L+  GI+ 
Sbjct: 67  YDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILLTAGIIF 126

Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186
             +G+  L+PVSWVA+  +++F++ ++ +   + E GEAL+LGW   L L++GG L  C 
Sbjct: 127 IITGMVVLIPVSWVANAIIRDFYN-SIVNVAQKRELGEALYLGWTTALVLIVGGALFCCV 185

Query: 187 AC 188
            C
Sbjct: 186 FC 187


>gi|4502877 claudin 4 [Homo sapiens]
          Length = 209

 Score =  117 bits (293), Expect = 8e-27
 Identities = 68/179 (37%), Positives = 105/179 (58%), Gaps = 5/179 (2%)

Query: 10  QLAGVSLSLLGWVLSCLTNYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQCKD 66
           Q+ G++L++LGW+   L   LP W+    +  N + + T+  GLW  CV+Q    MQCK 
Sbjct: 7   QVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCKV 66

Query: 67  FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
           +DS LALP +L+ +R L+ +S  +  LG+L+S  G  C    E +   K + +I+ G++ 
Sbjct: 67  YDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDE-SAKAKTMIVAGVVF 125

Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHC 185
             +G+  +VPVSW AH  +Q+F++  V     R E G +L++GW A   LLLGG LL C
Sbjct: 126 LLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKR-EMGASLYVGWAASGLLLLGGGLLCC 183


>gi|183979973 claudin 19 isoform a [Homo sapiens]
          Length = 224

 Score =  114 bits (286), Expect = 5e-26
 Identities = 69/190 (36%), Positives = 100/190 (52%), Gaps = 4/190 (2%)

Query: 10  QLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWT---MGLWQTCVIQEEVGMQCKD 66
           QL G  L+L GWV    +  LP WK  +   + +        GLW +C  Q    +QCK 
Sbjct: 7   QLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQCKL 66

Query: 67  FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
           +DS LAL   ++ +R LM ++  LGF+ +++S  G+ C R+G+S    K R+ I GG L 
Sbjct: 67  YDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGALF 126

Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186
             +G+  L  VSW A    QEF++ + P    R+EFG ALF+GW +    +LGG  L C 
Sbjct: 127 ILAGLCTLTAVSWYATLVTQEFFNPSTP-VNARYEFGPALFVGWASAGLAVLGGSFLCCT 185

Query: 187 ACSSHAPLAS 196
                 P +S
Sbjct: 186 CPEPERPNSS 195


>gi|183979975 claudin 19 isoform b [Homo sapiens]
          Length = 211

 Score =  114 bits (286), Expect = 5e-26
 Identities = 69/190 (36%), Positives = 100/190 (52%), Gaps = 4/190 (2%)

Query: 10  QLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWT---MGLWQTCVIQEEVGMQCKD 66
           QL G  L+L GWV    +  LP WK  +   + +        GLW +C  Q    +QCK 
Sbjct: 7   QLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQCKL 66

Query: 67  FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
           +DS LAL   ++ +R LM ++  LGF+ +++S  G+ C R+G+S    K R+ I GG L 
Sbjct: 67  YDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGALF 126

Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186
             +G+  L  VSW A    QEF++ + P    R+EFG ALF+GW +    +LGG  L C 
Sbjct: 127 ILAGLCTLTAVSWYATLVTQEFFNPSTP-VNARYEFGPALFVGWASAGLAVLGGSFLCCT 185

Query: 187 ACSSHAPLAS 196
                 P +S
Sbjct: 186 CPEPERPNSS 195


>gi|195947374 claudin 5 [Homo sapiens]
          Length = 303

 Score =  113 bits (282), Expect = 1e-25
 Identities = 70/181 (38%), Positives = 101/181 (55%), Gaps = 5/181 (2%)

Query: 10  QLAGVSLSLLGWVLSCLTNYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQCKD 66
           ++ G+ L L+GW    L   LP W+    LD N +   T   GLW +CV+Q    MQCK 
Sbjct: 92  EILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKV 151

Query: 67  FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
           +DS LAL  E++ +R L   +  L F+ L V+  G  C     +    K R+ + GG+L 
Sbjct: 152 YDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKARVALTGGVLY 210

Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186
              G+ ALVP+ W A+  V+EF+D +VP    ++E G AL++GW A   L++GGCLL C 
Sbjct: 211 LFCGLLALVPLCWFANIVVREFYDPSVP-VSQKYELGAALYIGWAATALLMVGGCLLCCG 269

Query: 187 A 187
           A
Sbjct: 270 A 270


>gi|195947372 claudin 5 [Homo sapiens]
          Length = 303

 Score =  113 bits (282), Expect = 1e-25
 Identities = 70/181 (38%), Positives = 101/181 (55%), Gaps = 5/181 (2%)

Query: 10  QLAGVSLSLLGWVLSCLTNYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQCKD 66
           ++ G+ L L+GW    L   LP W+    LD N +   T   GLW +CV+Q    MQCK 
Sbjct: 92  EILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKV 151

Query: 67  FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
           +DS LAL  E++ +R L   +  L F+ L V+  G  C     +    K R+ + GG+L 
Sbjct: 152 YDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKARVALTGGVLY 210

Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186
              G+ ALVP+ W A+  V+EF+D +VP    ++E G AL++GW A   L++GGCLL C 
Sbjct: 211 LFCGLLALVPLCWFANIVVREFYDPSVP-VSQKYELGAALYIGWAATALLMVGGCLLCCG 269

Query: 187 A 187
           A
Sbjct: 270 A 270


>gi|4502875 claudin 3 [Homo sapiens]
          Length = 220

 Score =  112 bits (281), Expect = 2e-25
 Identities = 63/180 (35%), Positives = 102/180 (56%), Gaps = 5/180 (2%)

Query: 10  QLAGVSLSLLGWVLSCLTNYLPHWKN---LNLDLNEMENWTMGLWQTCVIQEEVGMQCKD 66
           ++ G +L++LGW+ + +   LP W+    +  ++   +N   GLW  CV+Q    MQCK 
Sbjct: 6   EITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCKV 65

Query: 67  FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
           +DS LALP +L+ +R L+ ++  L   GLLV+  G  C    +     K ++ I+ G+L 
Sbjct: 66  YDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDD-TAKAKITIVAGVLF 124

Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186
             + +  LVPVSW A+  +++F++  VP+   R E G  L++GW A    LLGG LL C+
Sbjct: 125 LLAALLTLVPVSWSANTIIRDFYNPVVPEAQKR-EMGAGLYVGWAAAALQLLGGALLCCS 183


>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
          Length = 261

 Score =  107 bits (267), Expect = 8e-24
 Identities = 71/214 (33%), Positives = 102/214 (47%), Gaps = 13/214 (6%)

Query: 7   TVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64
           T  Q+    LS+LG         +  W   +L  N + +     GLW++CV Q     +C
Sbjct: 4   TTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGFTEC 63

Query: 65  KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
           + + + L LPA L+  R LM +   LG +GLLVS F L C+RIG  +   K  + +  GI
Sbjct: 64  RPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGI 123

Query: 125 LSWASGVTALVPVSWVAHKTVQEFWDEN----------VPDFVPRWEFGEALFLGWFAGL 174
           +   SG+ A+  VS  A+  V  FW             V     R+ FG ALF+GW AG 
Sbjct: 124 MFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGG 183

Query: 175 SLLLGGCLLHCAACSSHAPLASGHYAVAQTQDHH 208
             L+GG ++ C AC   AP  + + AV+     H
Sbjct: 184 LTLIGGVMM-CIACRGLAPEETNYKAVSYHASGH 216


>gi|6912316 claudin 17 [Homo sapiens]
          Length = 224

 Score =  107 bits (267), Expect = 8e-24
 Identities = 69/212 (32%), Positives = 106/212 (50%), Gaps = 6/212 (2%)

Query: 10  QLAGVSLSLLGWVLSCLTNYLPHWKN---LNLDLNEMENWTMGLWQTCVIQEEVGMQCKD 66
           Q+AG+ L  LG V +  T  LP W+    +  ++   E    GLW  C+ Q  V +QCK 
Sbjct: 7   QIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARVRLQCKF 66

Query: 67  FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
           + S LALP  L  +R LM ++  L  + LL+   G+  ++   S    K  LL   G+L 
Sbjct: 67  YSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLGTSGVLF 126

Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186
             +G+  L+PVSW A+  +++F++  +     + E G ALFLGW +   L +GG LL C 
Sbjct: 127 ILTGIFVLIPVSWTANIIIRDFYNPAI-HIGQKRELGAALFLGWASAAVLFIGGGLL-CG 184

Query: 187 ACSSHAPLASGHYAVAQTQDHHQELETRNTNL 218
            C  +       Y V   +  H + + RNT +
Sbjct: 185 FCCCNRKKQGYRYPVPGYRVPHTD-KRRNTTM 215


>gi|225703142 claudin 14 [Homo sapiens]
          Length = 239

 Score =  107 bits (266), Expect = 1e-23
 Identities = 65/190 (34%), Positives = 100/190 (52%), Gaps = 6/190 (3%)

Query: 7   TVAQLAGVSLSLLGWVLSCLTNYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63
           T  QL G  LS LG V + +T  LPHW+   ++  ++    ++  GLW  CV       Q
Sbjct: 4   TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63

Query: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
           C+ + S LALP +L+ +R LM +S  L  +    +  G+ C R  +     K    ILGG
Sbjct: 64  CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122

Query: 124 ILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
            L   +G+  +V VSW  +  VQ F++  +P  + ++E G+AL+LG+ +    L+GG LL
Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181

Query: 184 HCAACSSHAP 193
            C +C   AP
Sbjct: 182 -CLSCQDEAP 190


>gi|21536294 claudin 14 [Homo sapiens]
          Length = 239

 Score =  107 bits (266), Expect = 1e-23
 Identities = 65/190 (34%), Positives = 100/190 (52%), Gaps = 6/190 (3%)

Query: 7   TVAQLAGVSLSLLGWVLSCLTNYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63
           T  QL G  LS LG V + +T  LPHW+   ++  ++    ++  GLW  CV       Q
Sbjct: 4   TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63

Query: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
           C+ + S LALP +L+ +R LM +S  L  +    +  G+ C R  +     K    ILGG
Sbjct: 64  CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122

Query: 124 ILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
            L   +G+  +V VSW  +  VQ F++  +P  + ++E G+AL+LG+ +    L+GG LL
Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181

Query: 184 HCAACSSHAP 193
            C +C   AP
Sbjct: 182 -CLSCQDEAP 190


>gi|225703138 claudin 14 [Homo sapiens]
          Length = 239

 Score =  107 bits (266), Expect = 1e-23
 Identities = 65/190 (34%), Positives = 100/190 (52%), Gaps = 6/190 (3%)

Query: 7   TVAQLAGVSLSLLGWVLSCLTNYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63
           T  QL G  LS LG V + +T  LPHW+   ++  ++    ++  GLW  CV       Q
Sbjct: 4   TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63

Query: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
           C+ + S LALP +L+ +R LM +S  L  +    +  G+ C R  +     K    ILGG
Sbjct: 64  CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122

Query: 124 ILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
            L   +G+  +V VSW  +  VQ F++  +P  + ++E G+AL+LG+ +    L+GG LL
Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181

Query: 184 HCAACSSHAP 193
            C +C   AP
Sbjct: 182 -CLSCQDEAP 190


>gi|6912314 claudin 14 [Homo sapiens]
          Length = 239

 Score =  107 bits (266), Expect = 1e-23
 Identities = 65/190 (34%), Positives = 100/190 (52%), Gaps = 6/190 (3%)

Query: 7   TVAQLAGVSLSLLGWVLSCLTNYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63
           T  QL G  LS LG V + +T  LPHW+   ++  ++    ++  GLW  CV       Q
Sbjct: 4   TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63

Query: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
           C+ + S LALP +L+ +R LM +S  L  +    +  G+ C R  +     K    ILGG
Sbjct: 64  CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122

Query: 124 ILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
            L   +G+  +V VSW  +  VQ F++  +P  + ++E G+AL+LG+ +    L+GG LL
Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181

Query: 184 HCAACSSHAP 193
            C +C   AP
Sbjct: 182 -CLSCQDEAP 190


>gi|225703140 claudin 14 [Homo sapiens]
          Length = 239

 Score =  107 bits (266), Expect = 1e-23
 Identities = 65/190 (34%), Positives = 100/190 (52%), Gaps = 6/190 (3%)

Query: 7   TVAQLAGVSLSLLGWVLSCLTNYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63
           T  QL G  LS LG V + +T  LPHW+   ++  ++    ++  GLW  CV       Q
Sbjct: 4   TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63

Query: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
           C+ + S LALP +L+ +R LM +S  L  +    +  G+ C R  +     K    ILGG
Sbjct: 64  CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122

Query: 124 ILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
            L   +G+  +V VSW  +  VQ F++  +P  + ++E G+AL+LG+ +    L+GG LL
Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181

Query: 184 HCAACSSHAP 193
            C +C   AP
Sbjct: 182 -CLSCQDEAP 190


>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
          Length = 261

 Score =  105 bits (262), Expect = 3e-23
 Identities = 71/215 (33%), Positives = 103/215 (47%), Gaps = 15/215 (6%)

Query: 7   TVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEME---NWTMGLWQTCVIQEEVGMQ 63
           T  Q  G  +SL+G         +  W   +L  N +    N+  GLW++CV +     +
Sbjct: 4   TACQGLGFVVSLIGIAGIIAATCMDQWSTQDLYNNPVTAVFNY-QGLWRSCVRESSGFTE 62

Query: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
           C+ + + L LPA L+  R LM +   LG +GLLVS F L C+RIG  +   K  + +  G
Sbjct: 63  CRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSG 122

Query: 124 ILSWASGVTALVPVSWVAHKTVQEFWDEN----------VPDFVPRWEFGEALFLGWFAG 173
           I+   SG+ A+  VS  A+  V  FW             V     R+ FG ALF+GW AG
Sbjct: 123 IMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAG 182

Query: 174 LSLLLGGCLLHCAACSSHAPLASGHYAVAQTQDHH 208
              L+GG ++ C AC   AP  + + AV+     H
Sbjct: 183 GLTLIGGVMM-CIACRGLAPEETNYKAVSYHASGH 216


>gi|9966781 claudin 2 [Homo sapiens]
          Length = 230

 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 60/199 (30%), Positives = 100/199 (50%), Gaps = 7/199 (3%)

Query: 10  QLAGVSLSLLGWVLSCLTNYLPHWKN---LNLDLNEMENWTMGLWQTCVIQEEVGMQCKD 66
           QL G  L LLG + + +   LP WK    +   +     ++ GLW  C        QC  
Sbjct: 7   QLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGITQCDI 66

Query: 67  FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
           + + L LPA+++ ++ +M  S+ +  L  ++S  G+ C    +  R  K R+ + GG+  
Sbjct: 67  YSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESR-AKDRVAVAGGVFF 125

Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186
              G+   +PV+W  H  +++F+   VPD + ++E GEAL+LG  + L  L+ G +L C 
Sbjct: 126 ILGGLLGFIPVAWNLHGILRDFYSPLVPDSM-KFEIGEALYLGIISSLFSLIAGIIL-CF 183

Query: 187 ACSSHAPLASGHYAVAQTQ 205
           +CSS     S +Y   Q Q
Sbjct: 184 SCSSQRN-RSNYYDAYQAQ 201


>gi|5921465 claudin 10 isoform b [Homo sapiens]
          Length = 228

 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 64/188 (34%), Positives = 98/188 (52%), Gaps = 8/188 (4%)

Query: 7   TVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64
           T +++    +S+ GWVL   T    +WK   +D   +   T    LW+ CV        C
Sbjct: 4   TASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNC 63

Query: 65  KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124
           KDF S LAL   ++  R LM  +  LGF G + + FG+ C ++G S +  K ++  L GI
Sbjct: 64  KDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDK-AKAKIACLAGI 122

Query: 125 LSWASGVTALVPVSWVAHKTVQEFWDENVPDFV-PRWEFGEALFLGWFAGLSLLLGGCLL 183
           +   SG+ ++   S  A+K   EF+D   P FV  ++E G ALF+GW AG SL + G ++
Sbjct: 123 VFILSGLCSMTGCSLYANKITTEFFD---PLFVEQKYELGAALFIGW-AGASLCIIGGVI 178

Query: 184 HCAACSSH 191
            C + S +
Sbjct: 179 FCFSISDN 186


>gi|7656981 claudin 15 [Homo sapiens]
          Length = 228

 Score = 91.3 bits (225), Expect = 6e-19
 Identities = 62/189 (32%), Positives = 93/189 (49%), Gaps = 8/189 (4%)

Query: 13  GVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQCKDFDSF 70
           G  ++ +G ++  +T    +W+   +  N +   T+   LW +C         C +F S 
Sbjct: 9   GFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYNCWEFPSM 68

Query: 71  LALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILSWASG 130
           LAL   ++  R LM  +  LGFLGLL+   GL C  IG  +   K +L    G L   +G
Sbjct: 69  LALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGALHILAG 128

Query: 131 VTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCAAC-- 188
           +  +V +SW A    ++F+D   P    ++E G AL+LGW A L  +LGG  L C+AC  
Sbjct: 129 ICGMVAISWYAFNITRDFFDPLYPG--TKYELGPALYLGWSASLISILGGLCL-CSACCC 185

Query: 189 -SSHAPLAS 196
            S   P AS
Sbjct: 186 GSDEDPAAS 194


>gi|47716519 claudin 20 [Homo sapiens]
          Length = 219

 Score = 79.7 bits (195), Expect = 2e-15
 Identities = 53/195 (27%), Positives = 92/195 (47%), Gaps = 13/195 (6%)

Query: 11  LAGVSLSLLGWVLSC-------LTNYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEV 60
           +A   L LL ++L+            LP+WK N+++D N +       GLW  C      
Sbjct: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60

Query: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120
              C    S L+LP  ++ +R  M L+  L  LG+  S  G+ C R+G   R+ K     
Sbjct: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLG-GDRETKSHASF 119

Query: 121 LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180
            GG+   ++G+++L+   W   + +  F D  VP+   + E G A+++G+ + + L + G
Sbjct: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPE-SNKHEPGGAIYIGFISAMLLFISG 178

Query: 181 CLLHCAACSSHAPLA 195
            ++ C +C    P A
Sbjct: 179 -MIFCTSCIKRNPEA 192


>gi|33598916 claudin 10 isoform a [Homo sapiens]
          Length = 226

 Score = 72.8 bits (177), Expect = 2e-13
 Identities = 46/144 (31%), Positives = 74/144 (51%), Gaps = 6/144 (4%)

Query: 49  GLWQTCVIQEEVGMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIG 108
           GLW  C         C+   +   +   ++  R LM  +  LGF G + + FG+ C ++G
Sbjct: 46  GLWMNCAGNALGSFHCRPHFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVG 105

Query: 109 ESQRDLKRRLLILGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFV-PRWEFGEALF 167
            S +  K ++  L GI+   SG+ ++   S  A+K   EF+D   P FV  ++E G ALF
Sbjct: 106 GSDK-AKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFD---PLFVEQKYELGAALF 161

Query: 168 LGWFAGLSLLLGGCLLHCAACSSH 191
           +GW AG SL + G ++ C + S +
Sbjct: 162 IGW-AGASLCIIGGVIFCFSISDN 184


>gi|10938016 claudin 11 [Homo sapiens]
          Length = 207

 Score = 65.9 bits (159), Expect = 3e-11
 Identities = 52/194 (26%), Positives = 79/194 (40%), Gaps = 21/194 (10%)

Query: 7   TVAQLAGVSLSLLGWVLSCLTNYLPHWK-----NLNLDLNEMENWTMGLWQTCVIQEEVG 61
           T  Q+ G   S +GW+   +T     W       +       E  + GLW  CV+   + 
Sbjct: 4   TCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVMATGL- 62

Query: 62  MQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLIL 121
             CK     L LP  ++  R LM  ++ LG   +L+    L C+R+G+     K R   L
Sbjct: 63  YHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRAQL 122

Query: 122 GGILSWASGVTALVPVSW---VAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLL 178
            G+L     + ALV   W    AH+                  FG +L+ GW   +  L+
Sbjct: 123 AGVLLILLALCALVATIWFPVCAHRETTIV------------SFGYSLYAGWIGAVLCLV 170

Query: 179 GGCLLHCAACSSHA 192
           GGC++ C A  + A
Sbjct: 171 GGCVILCCAGDAQA 184


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.139    0.457 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,420,934
Number of Sequences: 37866
Number of extensions: 357022
Number of successful extensions: 1177
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1076
Number of HSP's gapped (non-prelim): 49
length of query: 220
length of database: 18,247,518
effective HSP length: 98
effective length of query: 122
effective length of database: 14,536,650
effective search space: 1773471300
effective search space used: 1773471300
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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