BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|162417973 claudin 22 [Homo sapiens] (220 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|162417973 claudin 22 [Homo sapiens] 457 e-129 gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] 399 e-112 gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] 398 e-111 gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] 398 e-111 gi|157820127 claudin-like [Homo sapiens] 230 6e-61 gi|153792186 claudin 7 [Homo sapiens] 127 1e-29 gi|153792768 claudin 6 [Homo sapiens] 125 4e-29 gi|11141861 claudin 9 [Homo sapiens] 120 1e-27 gi|10863887 claudin 1 [Homo sapiens] 120 1e-27 gi|40788011 claudin 8 [Homo sapiens] 120 1e-27 gi|4502877 claudin 4 [Homo sapiens] 117 8e-27 gi|183979973 claudin 19 isoform a [Homo sapiens] 114 5e-26 gi|183979975 claudin 19 isoform b [Homo sapiens] 114 5e-26 gi|195947374 claudin 5 [Homo sapiens] 113 1e-25 gi|195947372 claudin 5 [Homo sapiens] 113 1e-25 gi|4502875 claudin 3 [Homo sapiens] 112 2e-25 gi|7705961 claudin 18 isoform 1 [Homo sapiens] 107 8e-24 gi|6912316 claudin 17 [Homo sapiens] 107 8e-24 gi|225703142 claudin 14 [Homo sapiens] 107 1e-23 gi|21536294 claudin 14 [Homo sapiens] 107 1e-23 gi|225703138 claudin 14 [Homo sapiens] 107 1e-23 gi|6912314 claudin 14 [Homo sapiens] 107 1e-23 gi|225703140 claudin 14 [Homo sapiens] 107 1e-23 gi|50345279 claudin 18 isoform 2 [Homo sapiens] 105 3e-23 gi|9966781 claudin 2 [Homo sapiens] 99 4e-21 gi|5921465 claudin 10 isoform b [Homo sapiens] 99 4e-21 gi|7656981 claudin 15 [Homo sapiens] 91 6e-19 gi|47716519 claudin 20 [Homo sapiens] 80 2e-15 gi|33598916 claudin 10 isoform a [Homo sapiens] 73 2e-13 gi|10938016 claudin 11 [Homo sapiens] 66 3e-11 >gi|162417973 claudin 22 [Homo sapiens] Length = 220 Score = 457 bits (1177), Expect = e-129 Identities = 220/220 (100%), Positives = 220/220 (100%) Query: 1 MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60 MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV Sbjct: 1 MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60 Query: 61 GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120 GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI Sbjct: 61 GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120 Query: 121 LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180 LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG Sbjct: 121 LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180 Query: 181 CLLHCAACSSHAPLASGHYAVAQTQDHHQELETRNTNLKH 220 CLLHCAACSSHAPLASGHYAVAQTQDHHQELETRNTNLKH Sbjct: 181 CLLHCAACSSHAPLASGHYAVAQTQDHHQELETRNTNLKH 220 >gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] Length = 220 Score = 399 bits (1026), Expect = e-112 Identities = 192/212 (90%), Positives = 198/212 (93%) Query: 1 MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60 MAL+FRT Q G+ LSLLGW+LS +T YLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV Sbjct: 1 MALIFRTAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60 Query: 61 GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120 GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI Sbjct: 61 GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120 Query: 121 LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180 LGGILSWASG+TALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG Sbjct: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180 Query: 181 CLLHCAACSSHAPLASGHYAVAQTQDHHQELE 212 CLL+CAACSSHAPLA GHYAVAQ Q LE Sbjct: 181 CLLNCAACSSHAPLALGHYAVAQMQTQCPYLE 212 >gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] Length = 220 Score = 398 bits (1022), Expect = e-111 Identities = 191/212 (90%), Positives = 197/212 (92%) Query: 1 MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60 MAL+FRT Q G+ LS LGW+LS +T YLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV Sbjct: 1 MALIFRTAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60 Query: 61 GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120 GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI Sbjct: 61 GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120 Query: 121 LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180 LGGILSWASG+TALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG Sbjct: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180 Query: 181 CLLHCAACSSHAPLASGHYAVAQTQDHHQELE 212 CLL+CAACSSHAPLA GHYAVAQ Q LE Sbjct: 181 CLLNCAACSSHAPLALGHYAVAQMQTQCPYLE 212 >gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] Length = 220 Score = 398 bits (1022), Expect = e-111 Identities = 191/212 (90%), Positives = 197/212 (92%) Query: 1 MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60 MAL+FRT Q G+ LS LGW+LS +T YLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV Sbjct: 1 MALIFRTAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60 Query: 61 GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120 GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI Sbjct: 61 GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120 Query: 121 LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180 LGGILSWASG+TALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG Sbjct: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180 Query: 181 CLLHCAACSSHAPLASGHYAVAQTQDHHQELE 212 CLL+CAACSSHAPLA GHYAVAQ Q LE Sbjct: 181 CLLNCAACSSHAPLALGHYAVAQMQTQCPYLE 212 >gi|157820127 claudin-like [Homo sapiens] Length = 229 Score = 230 bits (587), Expect = 6e-61 Identities = 108/188 (57%), Positives = 136/188 (72%) Query: 1 MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60 MA FR QL G+ LSLLGWV SC+T LP WK LNL+LNEME W MG+W+ CV +EEV Sbjct: 1 MAWSFRAKVQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWIMGIWEVCVDREEV 60 Query: 61 GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120 CK F+SFL+LP EL+V+RILM S+GLG LGLL+ FG +C + + KRRL + Sbjct: 61 ATVCKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGL 120 Query: 121 LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180 LG L ++ T L+PVSWVAH T+Q+FWD+++PD +PRWEFG AL+LGW AG+ L LGG Sbjct: 121 LGRTLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGG 180 Query: 181 CLLHCAAC 188 LL +AC Sbjct: 181 LLLIFSAC 188 >gi|153792186 claudin 7 [Homo sapiens] Length = 211 Score = 127 bits (318), Expect = 1e-29 Identities = 68/180 (37%), Positives = 102/180 (56%), Gaps = 4/180 (2%) Query: 10 QLAGVSLSLLGWVLSCLTNYLPHWKNLNL---DLNEMENWTMGLWQTCVIQEEVGMQCKD 66 QL G S++LLGWV +P W+ + ++ + GLW CV Q M CK Sbjct: 7 QLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSCKM 66 Query: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126 +DS LAL A L+ +R LM +S LGFL + V+ G+ C R G + K R+ + GGI+ Sbjct: 67 YDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGGIIF 126 Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186 +G+ ALV SW H+ V +F++ +P + ++EFG A+F+GW ++LGG LL C+ Sbjct: 127 IVAGLAALVACSWYGHQIVTDFYNPLIPTNI-KYEFGPAIFIGWAGSALVILGGALLSCS 185 >gi|153792768 claudin 6 [Homo sapiens] Length = 220 Score = 125 bits (313), Expect = 4e-29 Identities = 77/193 (39%), Positives = 106/193 (54%), Gaps = 6/193 (3%) Query: 10 QLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTM---GLWQTCVIQEEVGMQCKD 66 Q+ GV L+LLGWV ++ LP WK N + + GLW +CV+Q MQCK Sbjct: 7 QILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKV 66 Query: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126 +DS LALP +L+ +R L ++ + GLLV G C E ++D K RL++ GI+ Sbjct: 67 YDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVE-EKDSKARLVLTSGIVF 125 Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186 SGV L+PV W AH +++F++ V + R E G +L+LGW A LLLGG LL C Sbjct: 126 VISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKR-ELGASLYLGWAASGLLLLGGGLL-CC 183 Query: 187 ACSSHAPLASGHY 199 C S HY Sbjct: 184 TCPSGGSQGPSHY 196 >gi|11141861 claudin 9 [Homo sapiens] Length = 217 Score = 120 bits (300), Expect = 1e-27 Identities = 68/182 (37%), Positives = 106/182 (58%), Gaps = 5/182 (2%) Query: 7 TVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTM---GLWQTCVIQEEVGMQ 63 T +L G++L++LGW+ + ++ LP WK N + + GLW +CV+Q MQ Sbjct: 4 TGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQ 63 Query: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123 CK +DS LALP +L+ +R L ++ L LGLLV+ G C E + K R+++ G Sbjct: 64 CKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDE-GAKARIVLTAG 122 Query: 124 ILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183 ++ +G+ L+PV W AH +Q+F++ V + + R E G +L+LGW A L+LGG LL Sbjct: 123 VILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKR-ELGASLYLGWAAAALLMLGGGLL 181 Query: 184 HC 185 C Sbjct: 182 CC 183 >gi|10863887 claudin 1 [Homo sapiens] Length = 211 Score = 120 bits (300), Expect = 1e-27 Identities = 65/180 (36%), Positives = 100/180 (55%), Gaps = 4/180 (2%) Query: 10 QLAGVSLSLLGWVLSCLTNYLPHWKNLNL---DLNEMENWTMGLWQTCVIQEEVGMQCKD 66 QL G L+ LGW+ + ++ LP W+ + ++ + GLW +CV Q +QCK Sbjct: 7 QLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCKV 66 Query: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126 FDS L L + L+ +R LM + LG + + V+ G+ C++ E K R+ ++GG + Sbjct: 67 FDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAIF 126 Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186 +G+ LV +W ++ VQEF+D P R+EFG+ALF GW A LLGG LL C+ Sbjct: 127 LLAGLAILVATAWYGNRIVQEFYDPMTP-VNARYEFGQALFTGWAAASLCLLGGALLCCS 185 >gi|40788011 claudin 8 [Homo sapiens] Length = 225 Score = 120 bits (300), Expect = 1e-27 Identities = 62/182 (34%), Positives = 103/182 (56%), Gaps = 4/182 (2%) Query: 10 QLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEM---ENWTMGLWQTCVIQEEVGMQCKD 66 ++AG+ L +G V + +P W+ N + EN+ GLW CV Q + MQCK Sbjct: 7 EIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANIRMQCKI 66 Query: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126 +DS LAL +L+ +R LM ++ + FL +++ G+ C R +K +L+ GI+ Sbjct: 67 YDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILLTAGIIF 126 Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186 +G+ L+PVSWVA+ +++F++ ++ + + E GEAL+LGW L L++GG L C Sbjct: 127 IITGMVVLIPVSWVANAIIRDFYN-SIVNVAQKRELGEALYLGWTTALVLIVGGALFCCV 185 Query: 187 AC 188 C Sbjct: 186 FC 187 >gi|4502877 claudin 4 [Homo sapiens] Length = 209 Score = 117 bits (293), Expect = 8e-27 Identities = 68/179 (37%), Positives = 105/179 (58%), Gaps = 5/179 (2%) Query: 10 QLAGVSLSLLGWVLSCLTNYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQCKD 66 Q+ G++L++LGW+ L LP W+ + N + + T+ GLW CV+Q MQCK Sbjct: 7 QVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCKV 66 Query: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126 +DS LALP +L+ +R L+ +S + LG+L+S G C E + K + +I+ G++ Sbjct: 67 YDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDE-SAKAKTMIVAGVVF 125 Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHC 185 +G+ +VPVSW AH +Q+F++ V R E G +L++GW A LLLGG LL C Sbjct: 126 LLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKR-EMGASLYVGWAASGLLLLGGGLLCC 183 >gi|183979973 claudin 19 isoform a [Homo sapiens] Length = 224 Score = 114 bits (286), Expect = 5e-26 Identities = 69/190 (36%), Positives = 100/190 (52%), Gaps = 4/190 (2%) Query: 10 QLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWT---MGLWQTCVIQEEVGMQCKD 66 QL G L+L GWV + LP WK + + + GLW +C Q +QCK Sbjct: 7 QLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQCKL 66 Query: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126 +DS LAL ++ +R LM ++ LGF+ +++S G+ C R+G+S K R+ I GG L Sbjct: 67 YDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGALF 126 Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186 +G+ L VSW A QEF++ + P R+EFG ALF+GW + +LGG L C Sbjct: 127 ILAGLCTLTAVSWYATLVTQEFFNPSTP-VNARYEFGPALFVGWASAGLAVLGGSFLCCT 185 Query: 187 ACSSHAPLAS 196 P +S Sbjct: 186 CPEPERPNSS 195 >gi|183979975 claudin 19 isoform b [Homo sapiens] Length = 211 Score = 114 bits (286), Expect = 5e-26 Identities = 69/190 (36%), Positives = 100/190 (52%), Gaps = 4/190 (2%) Query: 10 QLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWT---MGLWQTCVIQEEVGMQCKD 66 QL G L+L GWV + LP WK + + + GLW +C Q +QCK Sbjct: 7 QLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQCKL 66 Query: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126 +DS LAL ++ +R LM ++ LGF+ +++S G+ C R+G+S K R+ I GG L Sbjct: 67 YDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGALF 126 Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186 +G+ L VSW A QEF++ + P R+EFG ALF+GW + +LGG L C Sbjct: 127 ILAGLCTLTAVSWYATLVTQEFFNPSTP-VNARYEFGPALFVGWASAGLAVLGGSFLCCT 185 Query: 187 ACSSHAPLAS 196 P +S Sbjct: 186 CPEPERPNSS 195 >gi|195947374 claudin 5 [Homo sapiens] Length = 303 Score = 113 bits (282), Expect = 1e-25 Identities = 70/181 (38%), Positives = 101/181 (55%), Gaps = 5/181 (2%) Query: 10 QLAGVSLSLLGWVLSCLTNYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQCKD 66 ++ G+ L L+GW L LP W+ LD N + T GLW +CV+Q MQCK Sbjct: 92 EILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKV 151 Query: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126 +DS LAL E++ +R L + L F+ L V+ G C + K R+ + GG+L Sbjct: 152 YDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKARVALTGGVLY 210 Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186 G+ ALVP+ W A+ V+EF+D +VP ++E G AL++GW A L++GGCLL C Sbjct: 211 LFCGLLALVPLCWFANIVVREFYDPSVP-VSQKYELGAALYIGWAATALLMVGGCLLCCG 269 Query: 187 A 187 A Sbjct: 270 A 270 >gi|195947372 claudin 5 [Homo sapiens] Length = 303 Score = 113 bits (282), Expect = 1e-25 Identities = 70/181 (38%), Positives = 101/181 (55%), Gaps = 5/181 (2%) Query: 10 QLAGVSLSLLGWVLSCLTNYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQCKD 66 ++ G+ L L+GW L LP W+ LD N + T GLW +CV+Q MQCK Sbjct: 92 EILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKV 151 Query: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126 +DS LAL E++ +R L + L F+ L V+ G C + K R+ + GG+L Sbjct: 152 YDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKARVALTGGVLY 210 Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186 G+ ALVP+ W A+ V+EF+D +VP ++E G AL++GW A L++GGCLL C Sbjct: 211 LFCGLLALVPLCWFANIVVREFYDPSVP-VSQKYELGAALYIGWAATALLMVGGCLLCCG 269 Query: 187 A 187 A Sbjct: 270 A 270 >gi|4502875 claudin 3 [Homo sapiens] Length = 220 Score = 112 bits (281), Expect = 2e-25 Identities = 63/180 (35%), Positives = 102/180 (56%), Gaps = 5/180 (2%) Query: 10 QLAGVSLSLLGWVLSCLTNYLPHWKN---LNLDLNEMENWTMGLWQTCVIQEEVGMQCKD 66 ++ G +L++LGW+ + + LP W+ + ++ +N GLW CV+Q MQCK Sbjct: 6 EITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCKV 65 Query: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126 +DS LALP +L+ +R L+ ++ L GLLV+ G C + K ++ I+ G+L Sbjct: 66 YDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDD-TAKAKITIVAGVLF 124 Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186 + + LVPVSW A+ +++F++ VP+ R E G L++GW A LLGG LL C+ Sbjct: 125 LLAALLTLVPVSWSANTIIRDFYNPVVPEAQKR-EMGAGLYVGWAAAALQLLGGALLCCS 183 >gi|7705961 claudin 18 isoform 1 [Homo sapiens] Length = 261 Score = 107 bits (267), Expect = 8e-24 Identities = 71/214 (33%), Positives = 102/214 (47%), Gaps = 13/214 (6%) Query: 7 TVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64 T Q+ LS+LG + W +L N + + GLW++CV Q +C Sbjct: 4 TTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGFTEC 63 Query: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124 + + + L LPA L+ R LM + LG +GLLVS F L C+RIG + K + + GI Sbjct: 64 RPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGI 123 Query: 125 LSWASGVTALVPVSWVAHKTVQEFWDEN----------VPDFVPRWEFGEALFLGWFAGL 174 + SG+ A+ VS A+ V FW V R+ FG ALF+GW AG Sbjct: 124 MFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGG 183 Query: 175 SLLLGGCLLHCAACSSHAPLASGHYAVAQTQDHH 208 L+GG ++ C AC AP + + AV+ H Sbjct: 184 LTLIGGVMM-CIACRGLAPEETNYKAVSYHASGH 216 >gi|6912316 claudin 17 [Homo sapiens] Length = 224 Score = 107 bits (267), Expect = 8e-24 Identities = 69/212 (32%), Positives = 106/212 (50%), Gaps = 6/212 (2%) Query: 10 QLAGVSLSLLGWVLSCLTNYLPHWKN---LNLDLNEMENWTMGLWQTCVIQEEVGMQCKD 66 Q+AG+ L LG V + T LP W+ + ++ E GLW C+ Q V +QCK Sbjct: 7 QIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARVRLQCKF 66 Query: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126 + S LALP L +R LM ++ L + LL+ G+ ++ S K LL G+L Sbjct: 67 YSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLGTSGVLF 126 Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186 +G+ L+PVSW A+ +++F++ + + E G ALFLGW + L +GG LL C Sbjct: 127 ILTGIFVLIPVSWTANIIIRDFYNPAI-HIGQKRELGAALFLGWASAAVLFIGGGLL-CG 184 Query: 187 ACSSHAPLASGHYAVAQTQDHHQELETRNTNL 218 C + Y V + H + + RNT + Sbjct: 185 FCCCNRKKQGYRYPVPGYRVPHTD-KRRNTTM 215 >gi|225703142 claudin 14 [Homo sapiens] Length = 239 Score = 107 bits (266), Expect = 1e-23 Identities = 65/190 (34%), Positives = 100/190 (52%), Gaps = 6/190 (3%) Query: 7 TVAQLAGVSLSLLGWVLSCLTNYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63 T QL G LS LG V + +T LPHW+ ++ ++ ++ GLW CV Q Sbjct: 4 TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63 Query: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123 C+ + S LALP +L+ +R LM +S L + + G+ C R + K ILGG Sbjct: 64 CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122 Query: 124 ILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183 L +G+ +V VSW + VQ F++ +P + ++E G+AL+LG+ + L+GG LL Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181 Query: 184 HCAACSSHAP 193 C +C AP Sbjct: 182 -CLSCQDEAP 190 >gi|21536294 claudin 14 [Homo sapiens] Length = 239 Score = 107 bits (266), Expect = 1e-23 Identities = 65/190 (34%), Positives = 100/190 (52%), Gaps = 6/190 (3%) Query: 7 TVAQLAGVSLSLLGWVLSCLTNYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63 T QL G LS LG V + +T LPHW+ ++ ++ ++ GLW CV Q Sbjct: 4 TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63 Query: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123 C+ + S LALP +L+ +R LM +S L + + G+ C R + K ILGG Sbjct: 64 CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122 Query: 124 ILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183 L +G+ +V VSW + VQ F++ +P + ++E G+AL+LG+ + L+GG LL Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181 Query: 184 HCAACSSHAP 193 C +C AP Sbjct: 182 -CLSCQDEAP 190 >gi|225703138 claudin 14 [Homo sapiens] Length = 239 Score = 107 bits (266), Expect = 1e-23 Identities = 65/190 (34%), Positives = 100/190 (52%), Gaps = 6/190 (3%) Query: 7 TVAQLAGVSLSLLGWVLSCLTNYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63 T QL G LS LG V + +T LPHW+ ++ ++ ++ GLW CV Q Sbjct: 4 TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63 Query: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123 C+ + S LALP +L+ +R LM +S L + + G+ C R + K ILGG Sbjct: 64 CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122 Query: 124 ILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183 L +G+ +V VSW + VQ F++ +P + ++E G+AL+LG+ + L+GG LL Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181 Query: 184 HCAACSSHAP 193 C +C AP Sbjct: 182 -CLSCQDEAP 190 >gi|6912314 claudin 14 [Homo sapiens] Length = 239 Score = 107 bits (266), Expect = 1e-23 Identities = 65/190 (34%), Positives = 100/190 (52%), Gaps = 6/190 (3%) Query: 7 TVAQLAGVSLSLLGWVLSCLTNYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63 T QL G LS LG V + +T LPHW+ ++ ++ ++ GLW CV Q Sbjct: 4 TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63 Query: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123 C+ + S LALP +L+ +R LM +S L + + G+ C R + K ILGG Sbjct: 64 CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122 Query: 124 ILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183 L +G+ +V VSW + VQ F++ +P + ++E G+AL+LG+ + L+GG LL Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181 Query: 184 HCAACSSHAP 193 C +C AP Sbjct: 182 -CLSCQDEAP 190 >gi|225703140 claudin 14 [Homo sapiens] Length = 239 Score = 107 bits (266), Expect = 1e-23 Identities = 65/190 (34%), Positives = 100/190 (52%), Gaps = 6/190 (3%) Query: 7 TVAQLAGVSLSLLGWVLSCLTNYLPHWK---NLNLDLNEMENWTMGLWQTCVIQEEVGMQ 63 T QL G LS LG V + +T LPHW+ ++ ++ ++ GLW CV Q Sbjct: 4 TAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQ 63 Query: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123 C+ + S LALP +L+ +R LM +S L + + G+ C R + K ILGG Sbjct: 64 CQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKG-TPAKTTFAILGG 122 Query: 124 ILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183 L +G+ +V VSW + VQ F++ +P + ++E G+AL+LG+ + L+GG LL Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLL 181 Query: 184 HCAACSSHAP 193 C +C AP Sbjct: 182 -CLSCQDEAP 190 >gi|50345279 claudin 18 isoform 2 [Homo sapiens] Length = 261 Score = 105 bits (262), Expect = 3e-23 Identities = 71/215 (33%), Positives = 103/215 (47%), Gaps = 15/215 (6%) Query: 7 TVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEME---NWTMGLWQTCVIQEEVGMQ 63 T Q G +SL+G + W +L N + N+ GLW++CV + + Sbjct: 4 TACQGLGFVVSLIGIAGIIAATCMDQWSTQDLYNNPVTAVFNY-QGLWRSCVRESSGFTE 62 Query: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123 C+ + + L LPA L+ R LM + LG +GLLVS F L C+RIG + K + + G Sbjct: 63 CRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSG 122 Query: 124 ILSWASGVTALVPVSWVAHKTVQEFWDEN----------VPDFVPRWEFGEALFLGWFAG 173 I+ SG+ A+ VS A+ V FW V R+ FG ALF+GW AG Sbjct: 123 IMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAG 182 Query: 174 LSLLLGGCLLHCAACSSHAPLASGHYAVAQTQDHH 208 L+GG ++ C AC AP + + AV+ H Sbjct: 183 GLTLIGGVMM-CIACRGLAPEETNYKAVSYHASGH 216 >gi|9966781 claudin 2 [Homo sapiens] Length = 230 Score = 98.6 bits (244), Expect = 4e-21 Identities = 60/199 (30%), Positives = 100/199 (50%), Gaps = 7/199 (3%) Query: 10 QLAGVSLSLLGWVLSCLTNYLPHWKN---LNLDLNEMENWTMGLWQTCVIQEEVGMQCKD 66 QL G L LLG + + + LP WK + + ++ GLW C QC Sbjct: 7 QLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGITQCDI 66 Query: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126 + + L LPA+++ ++ +M S+ + L ++S G+ C + R K R+ + GG+ Sbjct: 67 YSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESR-AKDRVAVAGGVFF 125 Query: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186 G+ +PV+W H +++F+ VPD + ++E GEAL+LG + L L+ G +L C Sbjct: 126 ILGGLLGFIPVAWNLHGILRDFYSPLVPDSM-KFEIGEALYLGIISSLFSLIAGIIL-CF 183 Query: 187 ACSSHAPLASGHYAVAQTQ 205 +CSS S +Y Q Q Sbjct: 184 SCSSQRN-RSNYYDAYQAQ 201 >gi|5921465 claudin 10 isoform b [Homo sapiens] Length = 228 Score = 98.6 bits (244), Expect = 4e-21 Identities = 64/188 (34%), Positives = 98/188 (52%), Gaps = 8/188 (4%) Query: 7 TVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQC 64 T +++ +S+ GWVL T +WK +D + T LW+ CV C Sbjct: 4 TASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNC 63 Query: 65 KDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124 KDF S LAL ++ R LM + LGF G + + FG+ C ++G S + K ++ L GI Sbjct: 64 KDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDK-AKAKIACLAGI 122 Query: 125 LSWASGVTALVPVSWVAHKTVQEFWDENVPDFV-PRWEFGEALFLGWFAGLSLLLGGCLL 183 + SG+ ++ S A+K EF+D P FV ++E G ALF+GW AG SL + G ++ Sbjct: 123 VFILSGLCSMTGCSLYANKITTEFFD---PLFVEQKYELGAALFIGW-AGASLCIIGGVI 178 Query: 184 HCAACSSH 191 C + S + Sbjct: 179 FCFSISDN 186 >gi|7656981 claudin 15 [Homo sapiens] Length = 228 Score = 91.3 bits (225), Expect = 6e-19 Identities = 62/189 (32%), Positives = 93/189 (49%), Gaps = 8/189 (4%) Query: 13 GVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQCKDFDSF 70 G ++ +G ++ +T +W+ + N + T+ LW +C C +F S Sbjct: 9 GFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYNCWEFPSM 68 Query: 71 LALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILSWASG 130 LAL ++ R LM + LGFLGLL+ GL C IG + K +L G L +G Sbjct: 69 LALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGALHILAG 128 Query: 131 VTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCAAC-- 188 + +V +SW A ++F+D P ++E G AL+LGW A L +LGG L C+AC Sbjct: 129 ICGMVAISWYAFNITRDFFDPLYPG--TKYELGPALYLGWSASLISILGGLCL-CSACCC 185 Query: 189 -SSHAPLAS 196 S P AS Sbjct: 186 GSDEDPAAS 194 >gi|47716519 claudin 20 [Homo sapiens] Length = 219 Score = 79.7 bits (195), Expect = 2e-15 Identities = 53/195 (27%), Positives = 92/195 (47%), Gaps = 13/195 (6%) Query: 11 LAGVSLSLLGWVLSC-------LTNYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEV 60 +A L LL ++L+ LP+WK N+++D N + GLW C Sbjct: 1 MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60 Query: 61 GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120 C S L+LP ++ +R M L+ L LG+ S G+ C R+G R+ K Sbjct: 61 MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLG-GDRETKSHASF 119 Query: 121 LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180 GG+ ++G+++L+ W + + F D VP+ + E G A+++G+ + + L + G Sbjct: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPE-SNKHEPGGAIYIGFISAMLLFISG 178 Query: 181 CLLHCAACSSHAPLA 195 ++ C +C P A Sbjct: 179 -MIFCTSCIKRNPEA 192 >gi|33598916 claudin 10 isoform a [Homo sapiens] Length = 226 Score = 72.8 bits (177), Expect = 2e-13 Identities = 46/144 (31%), Positives = 74/144 (51%), Gaps = 6/144 (4%) Query: 49 GLWQTCVIQEEVGMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIG 108 GLW C C+ + + ++ R LM + LGF G + + FG+ C ++G Sbjct: 46 GLWMNCAGNALGSFHCRPHFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVG 105 Query: 109 ESQRDLKRRLLILGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFV-PRWEFGEALF 167 S + K ++ L GI+ SG+ ++ S A+K EF+D P FV ++E G ALF Sbjct: 106 GSDK-AKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFD---PLFVEQKYELGAALF 161 Query: 168 LGWFAGLSLLLGGCLLHCAACSSH 191 +GW AG SL + G ++ C + S + Sbjct: 162 IGW-AGASLCIIGGVIFCFSISDN 184 >gi|10938016 claudin 11 [Homo sapiens] Length = 207 Score = 65.9 bits (159), Expect = 3e-11 Identities = 52/194 (26%), Positives = 79/194 (40%), Gaps = 21/194 (10%) Query: 7 TVAQLAGVSLSLLGWVLSCLTNYLPHWK-----NLNLDLNEMENWTMGLWQTCVIQEEVG 61 T Q+ G S +GW+ +T W + E + GLW CV+ + Sbjct: 4 TCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVMATGL- 62 Query: 62 MQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLIL 121 CK L LP ++ R LM ++ LG +L+ L C+R+G+ K R L Sbjct: 63 YHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRAQL 122 Query: 122 GGILSWASGVTALVPVSW---VAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLL 178 G+L + ALV W AH+ FG +L+ GW + L+ Sbjct: 123 AGVLLILLALCALVATIWFPVCAHRETTIV------------SFGYSLYAGWIGAVLCLV 170 Query: 179 GGCLLHCAACSSHA 192 GGC++ C A + A Sbjct: 171 GGCVILCCAGDAQA 184 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.325 0.139 0.457 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,420,934 Number of Sequences: 37866 Number of extensions: 357022 Number of successful extensions: 1177 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 35 Number of HSP's successfully gapped in prelim test: 12 Number of HSP's that attempted gapping in prelim test: 1076 Number of HSP's gapped (non-prelim): 49 length of query: 220 length of database: 18,247,518 effective HSP length: 98 effective length of query: 122 effective length of database: 14,536,650 effective search space: 1773471300 effective search space used: 1773471300 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.