Guide to the Human Genome
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Search of human proteins with 162329583

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|162329583 cleavage and polyadenylation specific factor 6, 68
kD subunit [Homo sapiens]
         (551 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...  1177   0.0  
gi|217035107 pre-mRNA cleavage factor I, 59 kDa subunit isoform ...   362   e-100
gi|209862881 pre-mRNA cleavage factor I, 59 kDa subunit isoform ...   361   e-100
gi|217035102 pre-mRNA cleavage factor I, 59 kDa subunit isoform ...   361   e-100
gi|160707881 formin 2 [Homo sapiens]                                  140   4e-33
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...   135   1e-31
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]    134   3e-31
gi|7706501 WW domain binding protein 11 [Homo sapiens]                120   2e-27
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                    120   3e-27
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                    120   3e-27
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...   119   9e-27
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre...   112   1e-24
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...   110   4e-24
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...   108   1e-23
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...   108   1e-23
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]              108   1e-23
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...   108   1e-23
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   107   4e-23
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   107   4e-23
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   107   4e-23
gi|150417989 cyclin K isoform 1 [Homo sapiens]                        106   6e-23
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                105   1e-22
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...   105   1e-22
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      104   2e-22
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     103   5e-22
gi|146134388 YLP motif containing 1 [Homo sapiens]                    103   5e-22
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]       102   7e-22
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]       102   7e-22
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                102   9e-22
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...   101   2e-21

>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 1177 bits (3046), Expect = 0.0
 Identities = 551/551 (100%), Positives = 551/551 (100%)

Query: 1   MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDDVISPSANNGDAPEDRDYMDTLPPTV 60
           MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDDVISPSANNGDAPEDRDYMDTLPPTV
Sbjct: 1   MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDDVISPSANNGDAPEDRDYMDTLPPTV 60

Query: 61  GDDVGKGAAPNVVYTYTGKRIALYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRAN 120
           GDDVGKGAAPNVVYTYTGKRIALYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRAN
Sbjct: 61  GDDVGKGAAPNVVYTYTGKRIALYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRAN 120

Query: 121 GQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKTTQSGQM 180
           GQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKTTQSGQM
Sbjct: 121 GQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKTTQSGQM 180

Query: 181 SGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPP 240
           SGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPP
Sbjct: 181 SGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPP 240

Query: 241 LGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPV 300
           LGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPV
Sbjct: 241 LGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPV 300

Query: 301 PGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPA 360
           PGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPA
Sbjct: 301 PGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPA 360

Query: 361 FFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNR 420
           FFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNR
Sbjct: 361 FFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNR 420

Query: 421 NRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGI 480
           NRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGI
Sbjct: 421 NRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGI 480

Query: 481 ESKSYGSGSRRERSRERDHSRSREKSRRHKSRSRDRHDDYYRERSRERERHRDRDRDRDR 540
           ESKSYGSGSRRERSRERDHSRSREKSRRHKSRSRDRHDDYYRERSRERERHRDRDRDRDR
Sbjct: 481 ESKSYGSGSRRERSRERDHSRSREKSRRHKSRSRDRHDDYYRERSRERERHRDRDRDRDR 540

Query: 541 ERDREREYRHR 551
           ERDREREYRHR
Sbjct: 541 ERDREREYRHR 551


>gi|217035107 pre-mRNA cleavage factor I, 59 kDa subunit isoform 3
           [Homo sapiens]
          Length = 462

 Score =  362 bits (928), Expect = e-100
 Identities = 244/554 (44%), Positives = 303/554 (54%), Gaps = 110/554 (19%)

Query: 1   MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDDVISPSANNGDAPEDRDYMDTLPPTV 60
           M++GVD IDIYAD  EEFNQ+ E+   DQIDLYDDV++ ++   D   DR      PP V
Sbjct: 1   MSEGVDLIDIYAD--EEFNQDPEFNNTDQIDLYDDVLTATSQPSD---DRSSSTEPPPPV 55

Query: 61  GDDVG---KGAAPNVVYTYTG---KRIALYIGNLTWWTTDEDLTEAVHSLGVNDILEIKF 114
             +         P ++YTY+G   +R A+Y+G+ +WWTTD+ L + + S+GV D++E+KF
Sbjct: 56  RQEPSPKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKF 115

Query: 115 FENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKT 174
            ENRANGQSKG+A V V SE S  KL++LLP + L+G+   V P  +Q LSQFE Q+RK 
Sbjct: 116 AENRANGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKR 175

Query: 175 TQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQ 234
                        PP   SR +      GR     A P  +  P  A    PP   P   
Sbjct: 176 I------------PPRAHSRDS-SDSADGR-----ATPSENLVPSSARVDKPPSVLPYFN 217

Query: 235 TPPR--PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPL 292
            PP   P +G P PP PP         PPPL+   + G  PPPP +          L P 
Sbjct: 218 RPPSALPLMGLPPPPIPP---------PPPLSS--SFGVPPPPPGIH------YQHLMPP 260

Query: 293 PPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPP 352
           PP  PP +    PPPG  PP     P    F P P   +GPP         P     A  
Sbjct: 261 PPRLPPHLA--VPPPGAIPPALHLNP---AFFPPPNATVGPP---------PDTYMKASA 306

Query: 353 PAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEA 412
           P  H                S   GPPP                          + +SEA
Sbjct: 307 PYNHHG--------------SRDSGPPP--------------------------STVSEA 326

Query: 413 EFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISS 472
           EFE+IM RNRAISSSAIS+AVS ASAGDY  AIETL+TAI++IKQS+V+ D+RC+VLISS
Sbjct: 327 EFEDIMKRNRAISSSAISKAVSGASAGDYSDAIETLLTAIAVIKQSRVANDERCRVLISS 386

Query: 473 LQDCLHGIESKSY-----GSGSR-RERSRERDHSRSREKSRRHKS--RSRDRHDDYYRER 524
           L+DCLHGIE+KSY     GS SR R RSRER  SRSRE SRRH+    + DRHDDY++ER
Sbjct: 387 LKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQER 446

Query: 525 SRERERHRDRDRDR 538
           +RE ERHRDR+RDR
Sbjct: 447 NREHERHRDRERDR 460


>gi|209862881 pre-mRNA cleavage factor I, 59 kDa subunit isoform 2
           [Homo sapiens]
          Length = 471

 Score =  361 bits (927), Expect = e-100
 Identities = 245/554 (44%), Positives = 304/554 (54%), Gaps = 101/554 (18%)

Query: 1   MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDDVISPSANNGDAPEDRDYMDTLPPTV 60
           M++GVD IDIYAD  EEFNQ+ E+   DQIDLYDDV++ ++   D   DR      PP V
Sbjct: 1   MSEGVDLIDIYAD--EEFNQDPEFNNTDQIDLYDDVLTATSQPSD---DRSSSTEPPPPV 55

Query: 61  GDDVG---KGAAPNVVYTYTG---KRIALYIGNLTWWTTDEDLTEAVHSLGVNDILEIKF 114
             +         P ++YTY+G   +R A+Y+G+ +WWTTD+ L + + S+GV D++E+KF
Sbjct: 56  RQEPSPKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKF 115

Query: 115 FENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKT 174
            ENRANGQSKG+A V V SE S  KL++LLP + L+G+   V P  +Q LSQFE Q+RK 
Sbjct: 116 AENRANGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKR 175

Query: 175 TQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQ 234
                  G     PP   SR +      GR     A P  +  P  A    PP   P   
Sbjct: 176 ECVRVPRG---GIPPRAHSRDS-SDSADGR-----ATPSENLVPSSARVDKPPSVLPYFN 226

Query: 235 TPPR--PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPL 292
            PP   P +G P PP PP         PPPL+   + G  PPPP +          L P 
Sbjct: 227 RPPSALPLMGLPPPPIPP---------PPPLSS--SFGVPPPPPGIH------YQHLMPP 269

Query: 293 PPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPP 352
           PP  PP +    PPPG  PP     P    F P P   +GPP         P     A  
Sbjct: 270 PPRLPPHLA--VPPPGAIPPALHLNP---AFFPPPNATVGPP---------PDTYMKASA 315

Query: 353 PAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEA 412
           P  H                S   GPPP                          + +SEA
Sbjct: 316 PYNHHG--------------SRDSGPPP--------------------------STVSEA 335

Query: 413 EFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISS 472
           EFE+IM RNRAISSSAIS+AVS ASAGDY  AIETL+TAI++IKQS+V+ D+RC+VLISS
Sbjct: 336 EFEDIMKRNRAISSSAISKAVSGASAGDYSDAIETLLTAIAVIKQSRVANDERCRVLISS 395

Query: 473 LQDCLHGIESKSY-----GSGSR-RERSRERDHSRSREKSRRHKS--RSRDRHDDYYRER 524
           L+DCLHGIE+KSY     GS SR R RSRER  SRSRE SRRH+    + DRHDDY++ER
Sbjct: 396 LKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQER 455

Query: 525 SRERERHRDRDRDR 538
           +RE ERHRDR+RDR
Sbjct: 456 NREHERHRDRERDR 469


>gi|217035102 pre-mRNA cleavage factor I, 59 kDa subunit isoform 1
           [Homo sapiens]
          Length = 514

 Score =  361 bits (927), Expect = e-100
 Identities = 245/554 (44%), Positives = 304/554 (54%), Gaps = 101/554 (18%)

Query: 1   MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDDVISPSANNGDAPEDRDYMDTLPPTV 60
           M++GVD IDIYAD  EEFNQ+ E+   DQIDLYDDV++ ++   D   DR      PP V
Sbjct: 44  MSEGVDLIDIYAD--EEFNQDPEFNNTDQIDLYDDVLTATSQPSD---DRSSSTEPPPPV 98

Query: 61  GDDVG---KGAAPNVVYTYTG---KRIALYIGNLTWWTTDEDLTEAVHSLGVNDILEIKF 114
             +         P ++YTY+G   +R A+Y+G+ +WWTTD+ L + + S+GV D++E+KF
Sbjct: 99  RQEPSPKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKF 158

Query: 115 FENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKT 174
            ENRANGQSKG+A V V SE S  KL++LLP + L+G+   V P  +Q LSQFE Q+RK 
Sbjct: 159 AENRANGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKR 218

Query: 175 TQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQ 234
                  G     PP   SR +      GR     A P  +  P  A    PP   P   
Sbjct: 219 ECVRVPRG---GIPPRAHSRDS-SDSADGR-----ATPSENLVPSSARVDKPPSVLPYFN 269

Query: 235 TPPR--PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPL 292
            PP   P +G P PP PP         PPPL+   + G  PPPP +          L P 
Sbjct: 270 RPPSALPLMGLPPPPIPP---------PPPLSS--SFGVPPPPPGIH------YQHLMPP 312

Query: 293 PPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPP 352
           PP  PP +    PPPG  PP     P    F P P   +GPP         P     A  
Sbjct: 313 PPRLPPHLA--VPPPGAIPPALHLNP---AFFPPPNATVGPP---------PDTYMKASA 358

Query: 353 PAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEA 412
           P  H                S   GPPP                          + +SEA
Sbjct: 359 PYNHHG--------------SRDSGPPP--------------------------STVSEA 378

Query: 413 EFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISS 472
           EFE+IM RNRAISSSAIS+AVS ASAGDY  AIETL+TAI++IKQS+V+ D+RC+VLISS
Sbjct: 379 EFEDIMKRNRAISSSAISKAVSGASAGDYSDAIETLLTAIAVIKQSRVANDERCRVLISS 438

Query: 473 LQDCLHGIESKSY-----GSGSR-RERSRERDHSRSREKSRRHKS--RSRDRHDDYYRER 524
           L+DCLHGIE+KSY     GS SR R RSRER  SRSRE SRRH+    + DRHDDY++ER
Sbjct: 439 LKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQER 498

Query: 525 SRERERHRDRDRDR 538
           +RE ERHRDR+RDR
Sbjct: 499 NREHERHRDRERDR 512


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score =  140 bits (352), Expect = 4e-33
 Identities = 94/208 (45%), Positives = 101/208 (48%), Gaps = 24/208 (11%)

Query: 208  PGAVPGGDRFPGPAGPGG---PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLA 264
            P  +PG    P P  PG    PPPP P    PP PPL  PG   PP PP PG  +PPP  
Sbjct: 1044 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPP-P 1100

Query: 265  GPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG---PPPPVPGYGPPPGPPPPQQG-PPPPP 320
              P  G  PPPP+  PG   G PP  PLP     PPPP+PG G PP PP P+ G PPPPP
Sbjct: 1101 PLPGVGIPPPPPL--PGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPP 1156

Query: 321  GPFPPRPPGPLGPPLTLAPPPHLPG---PPP------GAPPPAPHVNPAFFPPPTNSGMP 371
             P    PP P  P   + PPP LPG   PPP      G PPP P       PPP   GM 
Sbjct: 1157 LPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMG 1216

Query: 372  TSDSRGPP-PTDPYGRPPPYDRGDYGPP 398
               +  PP P    G PPP      GPP
Sbjct: 1217 IPPAPAPPLPPPGTGIPPPPLLPVSGPP 1244



 Score =  138 bits (348), Expect = 1e-32
 Identities = 95/217 (43%), Positives = 103/217 (47%), Gaps = 27/217 (12%)

Query: 189  PGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGG---PPPPFPAGQTPPRPPLGPPG 245
            PG +     P  G G    P  +PG    P P  PG    PPPP P    PP PPL  PG
Sbjct: 949  PGAAIPPPPPLPGAGIP-LPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PG 1005

Query: 246  PPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG---PPPPVPG 302
               PP PP PG  +PPP    P  G  PPPP+  PG   G PP  PLP     PPPP+PG
Sbjct: 1006 AGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPL--PGA--GIPPPPPLPGAGIPPPPPLPG 1060

Query: 303  YGPPPGPPPPQQG-PPPPPGPFPPRPPGPLGPPLTLAPPPHLPG---PPP------GAPP 352
             G PP PP P  G PPPPP P    PP P  P   + PPP LPG   PPP      G PP
Sbjct: 1061 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP 1120

Query: 353  PAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389
            P P       PPP    +P +    PPP    G PPP
Sbjct: 1121 PPPLPGAGIPPPPP---LPGAGIPPPPPLPRVGIPPP 1154



 Score =  137 bits (346), Expect = 2e-32
 Identities = 90/198 (45%), Positives = 97/198 (48%), Gaps = 26/198 (13%)

Query: 208  PGAVPGGDRFPGPAGPGG---PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLA 264
            P  +PG    P P  PG    PPPP P    PP PPL  PG   PP PP PG  +PPP  
Sbjct: 978  PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPP-P 1034

Query: 265  GPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG---PPPPVPGYGPPPGPPPPQQG-PPPPP 320
              P  G  PPPP+  PG   G PP  PLP     PPPP+PG G PP PP P  G PPPPP
Sbjct: 1035 PLPGAGIPPPPPL--PGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1090

Query: 321  GPFPPRPPGPLGPPLTLAPPPHLPG---PPP------GAPPPAPHVNPAFFPPPTNSGMP 371
             P    PP P  P + + PPP LPG   PPP      G PPP P       PPP    +P
Sbjct: 1091 LPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP---LP 1147

Query: 372  TSDSRGPPPTDPYGRPPP 389
                  PPP    G PPP
Sbjct: 1148 RVGIPPPPPLPGAGIPPP 1165



 Score =  137 bits (346), Expect = 2e-32
 Identities = 90/198 (45%), Positives = 97/198 (48%), Gaps = 26/198 (13%)

Query: 208  PGAVPGGDRFPGPAGPGG---PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLA 264
            P  +PG    P P  PG    PPPP P    PP PPL  PG   PP PP PG  +PPP  
Sbjct: 1000 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPP-P 1056

Query: 265  GPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG---PPPPVPGYGPPPGPPPPQQG-PPPPP 320
              P  G  PPPP+  PG   G PP  PLP     PPPP+PG G PP PP P  G PPPPP
Sbjct: 1057 PLPGAGIPPPPPL--PGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1112

Query: 321  GPFPPRPPGPLGPPLTLAPPPHLPG---PPP------GAPPPAPHVNPAFFPPPTNSGMP 371
             P    PP P  P   + PPP LPG   PPP      G PPP P       PPP    +P
Sbjct: 1113 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPP---LP 1169

Query: 372  TSDSRGPPPTDPYGRPPP 389
             +    PPP    G PPP
Sbjct: 1170 GAGIPPPPPLPGVGIPPP 1187



 Score =  136 bits (343), Expect = 4e-32
 Identities = 89/198 (44%), Positives = 95/198 (47%), Gaps = 26/198 (13%)

Query: 208  PGAVPGGDRFPGPAGPGG---PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLA 264
            P  +PG    P P  PG    PPPP P    PP PPL   G P PP  P  G   PPPL 
Sbjct: 923  PPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPL- 981

Query: 265  GPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG---PPPPVPGYGPPPGPPPPQQG-PPPPP 320
              P  G  PPPP+  PG   G PP  PLP     PPPP+PG G PP PP P  G PPPPP
Sbjct: 982  --PGAGIPPPPPL--PGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1035

Query: 321  GPFPPRPPGPLGPPLTLAPPPHLPG---PPP------GAPPPAPHVNPAFFPPPTNSGMP 371
             P    PP P  P   + PPP LPG   PPP      G PPP P       PPP    +P
Sbjct: 1036 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP---LP 1092

Query: 372  TSDSRGPPPTDPYGRPPP 389
             +    PPP    G PPP
Sbjct: 1093 GAGIPPPPPLPGVGIPPP 1110



 Score =  130 bits (326), Expect = 4e-30
 Identities = 94/230 (40%), Positives = 100/230 (43%), Gaps = 30/230 (13%)

Query: 174  TTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPG-AVPGGDRFPGPAGPGGPPPPFPA 232
            T  S  M G G   PP        P  G      P  A+P      G      PPPP P 
Sbjct: 864  TESSSSMPGLGMVPPPPP------PLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG 917

Query: 233  GQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPL 292
               PP PPL  PG    P PP PG  +PPP   PP  G   PPP   PG     PP  PL
Sbjct: 918  AGIPPPPPL--PGAGILPLPPLPGAGIPPP---PPLPGAAIPPPPPLPGAGIPLPP--PL 970

Query: 293  PPG---PPPPVPGYGPPPGPPPPQQG-PPPPPGPFPPRPPGPLGPPLTLAPPPHLPG--- 345
            P     PPPP+PG G PP PP P  G PPPPP P    PP P  P   + PPP LPG   
Sbjct: 971  PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1030

Query: 346  PPP------GAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389
            PPP      G PPP P       PPP    +P +    PPP    G PPP
Sbjct: 1031 PPPPPLPGAGIPPPPPLPGAGIPPPPP---LPGAGIPPPPPLPGAGIPPP 1077



 Score =  128 bits (321), Expect = 2e-29
 Identities = 91/207 (43%), Positives = 100/207 (48%), Gaps = 24/207 (11%)

Query: 208  PGAVPGGDRFPGPAGPG---GPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLA 264
            P  +PG    P P  PG    PPPP P    PP PPL  PG   PP PP PG  +PPP  
Sbjct: 1088 PPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPP-- 1143

Query: 265  GPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG---PPPPVPGYGPPPGPPPPQQG-PPPPP 320
             P  R   PPPP L PG   G PP  PLP     PPPP+PG G PP PP P  G PPPPP
Sbjct: 1144 PPLPRVGIPPPPPL-PGA--GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP 1200

Query: 321  GP---FPPRPPGPLGPPLTLAPPPHLPGPPPGAPPP--APHVNPAFFPPPTNSGMPTSDS 375
             P    PP PP P G  +  AP P LP P  G PPP   P   P   P   +S +PT   
Sbjct: 1201 LPGAGIPPPPPLP-GMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQV 1259

Query: 376  RG----PPPTDPYGRPPPYDRGDYGPP 398
             G    P P+  +G     D+G    P
Sbjct: 1260 CGFLPPPLPSGLFGLGMNQDKGSRKQP 1286



 Score =  105 bits (261), Expect = 1e-22
 Identities = 77/203 (37%), Positives = 87/203 (42%), Gaps = 45/203 (22%)

Query: 227  PPPFPAGQTPPRPPLGPPGPPGPPGPPPPG--------------------QVLPPPLAGP 266
            PPP P  ++    P    G   PP PP PG                    ++LPPP    
Sbjct: 858  PPPLPCTESSSSMP--GLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915

Query: 267  PNRGDRPPPPV----LFPGQPF---GQPPLGPLPPG---PPPPVPGYGPPPGPPPPQQG- 315
            P  G  PPPP+    + P  P    G PP  PLP     PPPP+PG G P  PP P  G 
Sbjct: 916  PGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGI 975

Query: 316  PPPPPGPFPPRPPGPLGPPLTLAPPPHLPG---PPP------GAPPPAPHVNPAFFPPPT 366
            PPPPP P    PP P  P   + PPP LPG   PPP      G PPP P       PPP 
Sbjct: 976  PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1035

Query: 367  NSGMPTSDSRGPPPTDPYGRPPP 389
               +P +    PPP    G PPP
Sbjct: 1036 ---LPGAGIPPPPPLPGAGIPPP 1055



 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 79/234 (33%), Positives = 86/234 (36%), Gaps = 75/234 (32%)

Query: 228  PPFPAGQTPPRPPLGPPGPPGPPGPPPPGQV-----------------------LPPPL- 263
            P     Q PP P L      G PG  PP  +                        PPPL 
Sbjct: 803  PTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP 862

Query: 264  -----AGPPNRGDRPPPPVLFPGQPFGQPPLGPLP-----------PGPPPPVPGYGPPP 307
                 +  P  G  PPPP   PG      P   +P           P PPPP+PG G PP
Sbjct: 863  CTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPP 922

Query: 308  GPPPPQQG------------PPPPPGP---FPPRPP-----GPLGPPLT---LAPPPHLP 344
             PP P  G            PPPPP P    PP PP      PL PPL    + PPP LP
Sbjct: 923  PPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLP 982

Query: 345  G---PPP------GAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389
            G   PPP      G PPP P       PPP    +P +    PPP    G PPP
Sbjct: 983  GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP---LPGAGIPPPPPLPGAGIPPP 1033



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 66/255 (25%), Positives = 82/255 (32%), Gaps = 41/255 (16%)

Query: 161 KQFLSQFEMQSRKTTQSGQMSG-EGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFP- 218
           +Q   Q ++Q ++  Q  Q+ G E  A PP     A  PQ        PGA  G DRF  
Sbjct: 207 QQQQQQLQLQLQQQQQQQQLQGAEEPAAPP----TAVSPQ--------PGAFLGLDRFLL 254

Query: 219 GPAGPGGPPPPFPAGQ--------------TPPRPPLGPPGPPGPPGPPPPGQVLPPPLA 264
           GP+G  G  P  P  +                PR P  PP P G P    P      P A
Sbjct: 255 GPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAA 314

Query: 265 GPPNRGDRPPPPVLFPG-QPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPF 323
                    P P   PG +  G P  G            +   P   P ++  P      
Sbjct: 315 KDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDA 374

Query: 324 PPR--------PPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTN--SGMPTS 373
           P R          GP  P    A  P  P P      P P + P +    T   S    S
Sbjct: 375 PQRLGEEPEEEAQGPDAP--AAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHS 432

Query: 374 DSRGPPPTDPYGRPP 388
            S+ P  +    R P
Sbjct: 433 PSQSPNQSPRIKRRP 447



 Score = 29.3 bits (64), Expect = 9.8
 Identities = 23/87 (26%), Positives = 31/87 (35%), Gaps = 13/87 (14%)

Query: 316 PPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAP------------PPAPHVNPAF-F 362
           P  PP    P+P   LG    L  P    G  PG+P            P +    P    
Sbjct: 232 PAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQ 291

Query: 363 PPPTNSGMPTSDSRGPPPTDPYGRPPP 389
            PP+  G+P S++   P   P  +  P
Sbjct: 292 QPPSPGGLPVSEAPSLPAAQPAAKDSP 318


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score =  135 bits (339), Expect = 1e-31
 Identities = 96/250 (38%), Positives = 105/250 (42%), Gaps = 41/250 (16%)

Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP--PPFPAG---QTP 236
           G+ +  PP G ++   PQG    G+  G  P GD+   P  P G P  PP   G   Q P
Sbjct: 55  GKPQGPPPQGGNK---PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP 111

Query: 237 PRPPLGPPGPPG-----PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGP 291
           P PP  P GPP      P GPPPPG+   PP  G  +R  R PP     G+P G PP G 
Sbjct: 112 PPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPP-----GKPQGPPPQGG 166

Query: 292 LPPGPPPPVPG--YGPPPGPPPPQQGPPPPPGPFPPRPPG------------PLGPPLTL 337
             P  PPP PG   GPPP      QGPPPP  P  P P G            P GPP   
Sbjct: 167 NQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQG 226

Query: 338 APPPHLPGPPPGAP--PPAPHVNPAFFPPPTN-------SGMPTSDSRGPPPTDPYGRPP 388
              P  P PPPG P  PP    N    PPP          G   S S   PP  P G P 
Sbjct: 227 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQ 286

Query: 389 PYDRGDYGPP 398
                  GPP
Sbjct: 287 QEGNNPQGPP 296



 Score =  132 bits (332), Expect = 8e-31
 Identities = 98/256 (38%), Positives = 106/256 (41%), Gaps = 53/256 (20%)

Query: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG---PGGPPPPFPAGQTPP----RPP 240
           PP G  +   PQG + R   P + PG  + P P G   P GPPPP    Q PP      P
Sbjct: 72  PPPGKPQGPPPQGDKSRS--PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRP 129

Query: 241 LGPPGPPGPPGPPPPGQVL-----PP--PLAGPPNRGDRPPPPVLFPGQPFGQPPLG-PL 292
            GPP P  P GPPP G        PP  P   PP  G++P  P   PG+P G PP G   
Sbjct: 130 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK 189

Query: 293 PPGPPPPVPGYGPPP----------------GPPPP----QQGPPPPPG----------- 321
           P GPPPP    GPPP                GPPP      QGPPPPPG           
Sbjct: 190 PQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 249

Query: 322 -PFPPRPPG-PLGPPLTLAPPPHLPGPPPGAP--PPAPHVNPAFFPPPTNSGMPTSDSRG 377
            P  P PPG P GPP            PPG P  PP    N    PPP   G P    + 
Sbjct: 250 KPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNP-QQPQA 308

Query: 378 PPPTDPYGRPPPYDRG 393
           PP   P G P P   G
Sbjct: 309 PPAGQPQGPPRPPQGG 324



 Score =  127 bits (319), Expect = 3e-29
 Identities = 91/229 (39%), Positives = 99/229 (43%), Gaps = 50/229 (21%)

Query: 208 PGAVPGGDRFPGPAG---PGGPPPPFPAGQTPPRPPLGPPGPPG--PPGPPPPGQVLPPP 262
           P  + G  + P P G   P GPPPP       P  P GPP   G  P GPPPPG+   PP
Sbjct: 29  PSLIAGNPQGPSPQGGNKPQGPPPP-------PGKPQGPPPQGGNKPQGPPPPGKPQGPP 81

Query: 263 LAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPG--YGPPP-------GPPPP- 312
             G  +R  R PP     G+P G PP G   P  PPP PG   GPPP       GPPPP 
Sbjct: 82  PQGDKSRSPRSPP-----GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPG 136

Query: 313 -QQGPPP--PPGPFPPRPPG-PLGPPLTLAPPPHLPGPPPG---APPPAPHVNPAFFPPP 365
             QGPPP       P  PPG P GPP      P  P PPPG    PPP     P   PPP
Sbjct: 137 KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPP 196

Query: 366 -------------TNSGMPTSDSRGPPP---TDPYGRPPPYDRGDYGPP 398
                         +S  P    +GPPP     P G PPP  +    PP
Sbjct: 197 GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 245



 Score =  120 bits (301), Expect = 3e-27
 Identities = 87/229 (37%), Positives = 99/229 (43%), Gaps = 35/229 (15%)

Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP--PPFPAG---QTP 236
           G+ +  PP G +R   PQG    G+  G  P GD+   P  P G P  PP   G   Q P
Sbjct: 116 GKPQGPPPQGGNR---PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP 172

Query: 237 PRPPLGPPGPPG-----PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGP 291
           P PP  P GPP      P GPPPPG+   PP  G  +R  + PP     G+P G PP G 
Sbjct: 173 PPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPP-----GKPQGPPPQGG 227

Query: 292 LPPGPPPPVPG--YGPPP-------GPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPH 342
             P  PPP PG   GPPP       GPPPP + P  PP     +      PP     PP 
Sbjct: 228 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK-PQGPPAQGGSKSQSARSPPGKPQGPPQ 286

Query: 343 LPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP--PP 389
             G  P  PPP     PA   P      P    +GPP     GRP  PP
Sbjct: 287 QEGNNPQGPPP-----PAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 54/144 (37%), Positives = 56/144 (38%), Gaps = 34/144 (23%)

Query: 276 PVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPG---PFPPRPPG-PL 331
           P L  G P G  P G   P  PPP      PPG P      PPP G   P  P PPG P 
Sbjct: 29  PSLIAGNPQGPSPQGGNKPQGPPP------PPGKP----QGPPPQGGNKPQGPPPPGKPQ 78

Query: 332 GPP-------LTLAPPPHLPGPP------PGAPPPAPHVNPAFFPPPTNSGMPTSDSRGP 378
           GPP          +PP    GPP      P  PPP P       PPP     P      P
Sbjct: 79  GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG--PPPQGGNRPQGP---P 133

Query: 379 PPTDPYGRPPPYD--RGDYGPPGR 400
           PP  P G PP  D  R    PPG+
Sbjct: 134 PPGKPQGPPPQGDKSRSPRSPPGK 157



 Score = 32.7 bits (73), Expect = 0.89
 Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 16/78 (20%)

Query: 334 PLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP---TDPYGRPPPY 390
           P  +A  P  P P  G  P  P       PPP   G P    +GPPP     P G PPP 
Sbjct: 29  PSLIAGNPQGPSPQGGNKPQGP-------PPPP--GKP----QGPPPQGGNKPQGPPPPG 75

Query: 391 DRGDYGPPGREMDTARTP 408
                 P G +  + R+P
Sbjct: 76  KPQGPPPQGDKSRSPRSP 93


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score =  134 bits (336), Expect = 3e-31
 Identities = 97/245 (39%), Positives = 107/245 (43%), Gaps = 41/245 (16%)

Query: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG---PGGPPPPFPAGQTPP----RPP 240
           PP G  +   PQG + R   P + PG  + P P G   P GPPPP    Q PP      P
Sbjct: 93  PPPGKPQGPPPQGDKSRS--PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 150

Query: 241 LGPPGPPGPPGPPPPGQVL------PP--PLAGPPNRGDRPPPPVLFPGQPFGQPPLGP- 291
            GPP P  P GPPP G         PP  P   PP  G++P  P   PG+P G PP G  
Sbjct: 151 QGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 210

Query: 292 LPPGPPPPVPGYGPPP----------GPPPPQQGPPP-----PPGPFPPRPPGPLGPPLT 336
            P GPPPP    GPPP           PP   QGPPP     P GP PP P  P GPP  
Sbjct: 211 KPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGP-PPPPGKPQGPPPQ 269

Query: 337 LAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP---TDPYGRPPPYDRG 393
               P  P PPPG P   P   P       +S  P    +GPPP     P G PPP  + 
Sbjct: 270 GGNKPQGP-PPPGKPQGPP---PQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 325

Query: 394 DYGPP 398
              PP
Sbjct: 326 QGPPP 330



 Score =  131 bits (329), Expect = 2e-30
 Identities = 103/276 (37%), Positives = 114/276 (41%), Gaps = 72/276 (26%)

Query: 191 GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG---PGGPPPPFPAGQTPP----RPPLGP 243
           G+ + A PQGG  + + P + PG  + P P G   P GPPPP    Q PP      P GP
Sbjct: 34  GNPQGAPPQGGN-KPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 92

Query: 244 PGPPGPPGPPPPGQVL-----PP--PLAGPPNRGDRPPPPVLFPGQPFGQPPLGP-LPPG 295
           P P  P GPPP G        PP  P   PP  G++P  P   PG+P G PP G   P G
Sbjct: 93  PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 152

Query: 296 PPPPVPGYGPPP-----------------GPPPP----QQGPPPPPG------------P 322
           PPPP    GPPP                 GPPP      QGPPPPPG            P
Sbjct: 153 PPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 212

Query: 323 FPPRPPG-PLGPP--------LTLAPPPHLPGPPPGA------PPPAPHVNPAFFPPPTN 367
             P PPG P GPP           +PP    GPPP        PPP P       PPP  
Sbjct: 213 QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQG--PPPQG 270

Query: 368 SGMPTSDSRGPPPTDPYGRPP---PYDRGDYGPPGR 400
              P      PPP  P G PP      R    PPG+
Sbjct: 271 GNKPQGP---PPPGKPQGPPPQGGSKSRSSRSPPGK 303



 Score =  130 bits (326), Expect = 4e-30
 Identities = 95/246 (38%), Positives = 100/246 (40%), Gaps = 40/246 (16%)

Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG---PGGPPPPFPAGQTPP- 237
           G    GPP        P  G  + R   + PG  + P P G   P GPPPP    Q PP 
Sbjct: 147 GNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 206

Query: 238 ---RPPLGPPGPPGPPGPPPPGQ-----VLPPP--LAGPPNRGDR----PPPPVLFPGQP 283
                P GPP P  P GPPP G         PP    GPP +G      PPPP   PG+P
Sbjct: 207 QGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPP---PGKP 263

Query: 284 FGQPPL-GPLPPGPPPPVPGYGPPP----------GPPPPQQGPPPPPGPFPPRPPGPLG 332
            G PP  G  P GPPPP    GPPP           PP   QGPPP  G  P  PP P G
Sbjct: 264 QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG 323

Query: 333 PPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDR 392
            P    PPP     P G PPP     P   PP    G   S S   PP  P G P     
Sbjct: 324 KP--QGPPPQGGNKPQGPPPPGKPQGP---PP---QGGSKSRSARSPPGKPQGPPQQEGN 375

Query: 393 GDYGPP 398
              GPP
Sbjct: 376 NPQGPP 381



 Score =  119 bits (297), Expect = 9e-27
 Identities = 96/238 (40%), Positives = 106/238 (44%), Gaps = 51/238 (21%)

Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG--PGGPPPPFPAG----QT 235
           G+ +  PP G ++   PQG    G+  G  P GD     A   PG P  P P G    Q 
Sbjct: 199 GKPQGPPPQGGNK---PQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQG 255

Query: 236 PPRPPLGPPGPPG-----PPGPPPPGQVL-PPPLAGPPNRGDRPPPPVLFPGQPFGQPPL 289
           PP PP  P GPP      P GPPPPG+   PPP  G  +R  R PP     G+P G PP 
Sbjct: 256 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPP-----GKPQGPPPQ 310

Query: 290 GPLPPGPPPPVPG--YGPPP-------GPPPPQQGP--PPPPGPFPPR----PPG-PLGP 333
           G   P  PPP PG   GPPP       GPPPP + P  PPP G    R    PPG P GP
Sbjct: 311 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK-PQGPPPQGGSKSRSARSPPGKPQGP 369

Query: 334 PLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP--PP 389
           P      P  P PP G  P  P   PA        G P    +GPP     GRP  PP
Sbjct: 370 PQQEGNNPQGPPPPAGGNPQQPQAPPA--------GQP----QGPPRPPQGGRPSRPP 415



 Score =  115 bits (289), Expect = 8e-26
 Identities = 93/240 (38%), Positives = 99/240 (41%), Gaps = 60/240 (25%)

Query: 208 PGAVPGGDRFPGPAGPGGPP-PPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLA-- 264
           P  + G  +   P G   P  PP P G+    PP G   P GPP PPP     PPP    
Sbjct: 29  PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGN 87

Query: 265 ------------GPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPG--YGPPP--- 307
                       GPP +GD+   P   PG+P G PP G   P  PPP PG   GPPP   
Sbjct: 88  KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 147

Query: 308 ----GPPPP--QQGPPP-----------PPG-PFPPRPPG---PLGPPLTLAPPPHLP-G 345
               GPPPP   QGPPP           PPG P  P P G   P GPP    PPP  P G
Sbjct: 148 NKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP----PPPGKPQG 203

Query: 346 PPP-------GAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPP 398
           PPP       G PPP     P   PP    G   S S   PP  P G PP       GPP
Sbjct: 204 PPPQGGNKPQGPPPPGKPQGP---PP---QGDNKSQSARSPPGKPQGPPPQGGNQPQGPP 257



 Score =  101 bits (251), Expect = 2e-21
 Identities = 72/180 (40%), Positives = 75/180 (41%), Gaps = 36/180 (20%)

Query: 228 PPFPAGQTPPRPPLG---PPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPF 284
           P   AG     PP G   P GPP PPG P      PPP  G  N+   PPPP   PG+P 
Sbjct: 29  PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQG----PPPQGG--NQPQGPPPP---PGKPQ 79

Query: 285 GQPPLGP-LPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHL 343
           G PP G   P GPPPP    G P GPPP       P  P    P  P GPP      P  
Sbjct: 80  GPPPQGGNKPQGPPPP----GKPQGPPPQGDKSRSPRSP----PGKPQGPPPQGGNQPQG 131

Query: 344 PGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYD---RGDYGPPGR 400
           P PPPG P           PPP     P      PPP  P G PP  D   R    PPG+
Sbjct: 132 PPPPPGKPQG---------PPPQGGNKPQGP---PPPGKPQGPPPQGDNKSRSSRSPPGK 179



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 38/109 (34%), Positives = 42/109 (38%), Gaps = 32/109 (29%)

Query: 304 GPPPGPPPPQQGPPPPPGPFPPRPPG-PLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFF 362
           G P G PP  QG   P GP  P PPG P GPP      P  P PPPG P           
Sbjct: 34  GNPQGAPP--QGGNKPQGP--PSPPGKPQGPPPQGGNQPQGPPPPPGKP----------- 78

Query: 363 PPPTNSGMPTSDSRGPPP---TDPYGRPPPYDRGDYGPPGREMDTARTP 408
                        +GPPP     P G PPP       P G +  + R+P
Sbjct: 79  -------------QGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 114


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score =  120 bits (302), Expect = 2e-27
 Identities = 82/163 (50%), Positives = 89/163 (54%), Gaps = 20/163 (12%)

Query: 208 PGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPG--PPGPPPPGQVLPPPLAG 265
           P +VP   +   P  PG PPP  P    PP PPL PPGPP   PPGPPP     PP L  
Sbjct: 394 PQSVPPS-QIQAPPMPG-PPPLGP----PPAPPLRPPGPPTGLPPGPPPGA---PPFLRP 444

Query: 266 PPNRGDRPP-PPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFP 324
           P   G R P P +L PG P G+PP GP  PGPPP +P  GPPP  PPP+  PP PPG  P
Sbjct: 445 PGMPGLRGPLPRLLPPGPPPGRPP-GPP-PGPPPGLPP-GPPPRGPPPRLPPPAPPGIPP 501

Query: 325 PRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTN 367
           PR PG + PPL     P L   PPG  PPAP  NP     P N
Sbjct: 502 PR-PGMMRPPLV----PPLGPAPPGLFPPAPLPNPGVLSAPPN 539



 Score =  110 bits (276), Expect = 3e-24
 Identities = 69/152 (45%), Positives = 75/152 (49%), Gaps = 17/152 (11%)

Query: 249 PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPP----PPVPGY- 303
           PP   PP Q+  PP+ GPP  G  P PP+  PG P G PP GP P  PP    P +PG  
Sbjct: 393 PPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPP-GPPPGAPPFLRPPGMPGLR 451

Query: 304 GP-----PPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGP-PPGAPPPAPHV 357
           GP     PPGPPP +  P PPPGP P  PPGP  PP    PPP LP P PPG PPP P +
Sbjct: 452 GPLPRLLPPGPPPGRP-PGPPPGPPPGLPPGP--PPR--GPPPRLPPPAPPGIPPPRPGM 506

Query: 358 NPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389
                 PP     P      P P       PP
Sbjct: 507 MRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPP 538



 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 74/188 (39%), Positives = 83/188 (44%), Gaps = 20/188 (10%)

Query: 165 SQFEMQSRKT-TQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGP 223
           S+ E QS+K   +     G   A     +   + P         PG  P G     P  P
Sbjct: 364 SEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRP 423

Query: 224 GGPPPPFPAGQTPPRPP-LGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQ 282
            GPP   P G  P  PP L PPG PG  GP P  ++LPP   GPP      PPP   PG 
Sbjct: 424 PGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLP--RLLPP---GPPPGRPPGPPPGPPPGL 478

Query: 283 PFGQPPLGP-------LPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPL 335
           P G PP GP        PPG PPP PG   PP  PP     P PPG F   PP PL  P 
Sbjct: 479 PPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPL---GPAPPGLF---PPAPLPNPG 532

Query: 336 TLAPPPHL 343
            L+ PP+L
Sbjct: 533 VLSAPPNL 540



 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 43/92 (46%), Positives = 44/92 (47%), Gaps = 9/92 (9%)

Query: 313 QQGPPP--PPGPF--PPRP-PGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTN 367
           QQ PP   PP     PP P P PLGPP   APP   PGPP G PP  P   P F  PP  
Sbjct: 390 QQAPPQSVPPSQIQAPPMPGPPPLGPP--PAPPLRPPGPPTGLPPGPPPGAPPFLRPPGM 447

Query: 368 SGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPG 399
            G+     R  PP  P GRPP    G   PPG
Sbjct: 448 PGLRGPLPRLLPPGPPPGRPPGPPPGP--PPG 477



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 39/97 (40%), Positives = 40/97 (41%), Gaps = 20/97 (20%)

Query: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGP-PPPFPAGQTPPRP-----PL 241
           PPG       P  GR  G  PG  PG    P P GP    PPP P G  PPRP     PL
Sbjct: 459 PPG-------PPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPL 511

Query: 242 GPPGPPGPPGPPPPGQV-------LPPPLAGPPNRGD 271
            PP  P PPG  PP  +        PP L   P   D
Sbjct: 512 VPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADD 548



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 35/84 (41%), Positives = 39/84 (46%), Gaps = 20/84 (23%)

Query: 327 PPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP-TDPYG 385
           PP  + P    APP  +PGPPP  PPPAP + P         G PT    GPPP   P+ 
Sbjct: 393 PPQSVPPSQIQAPP--MPGPPPLGPPPAPPLRPP--------GPPTGLPPGPPPGAPPFL 442

Query: 386 RPP--PYDRGDY-------GPPGR 400
           RPP  P  RG          PPGR
Sbjct: 443 RPPGMPGLRGPLPRLLPPGPPPGR 466



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 28/64 (43%), Positives = 30/64 (46%), Gaps = 12/64 (18%)

Query: 250 PGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGP 309
           PG  PP  +      GPP R     P +L  G P        LPPG  PP    GPPPGP
Sbjct: 159 PGAQPPSILKKTSAYGPPTRAVSILP-LLGHGVP-------RLPPGRKPP----GPPPGP 206

Query: 310 PPPQ 313
           PPPQ
Sbjct: 207 PPPQ 210



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 11/77 (14%)

Query: 247 PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG----PLPPGPPPPVPG 302
           P P  P  P  +L   +  P  +    PP +L     +G P       PL     P +P 
Sbjct: 140 PLPDMPHAPSNILIQDIPLPGAQ----PPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP 195

Query: 303 YGPPPGPPPPQQGPPPP 319
              PPGPPP   GPPPP
Sbjct: 196 GRKPPGPPP---GPPPP 209



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 18/54 (33%)

Query: 291 PLPPGPPPPV----PGYGPP--------------PGPPPPQQGPPPPPGPFPPR 326
           PLP   PP +      YGPP              P  PP ++ P PPPGP PP+
Sbjct: 157 PLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQ 210



 Score = 33.5 bits (75), Expect = 0.52
 Identities = 24/78 (30%), Positives = 30/78 (38%), Gaps = 16/78 (20%)

Query: 335 LTLAPPPHLPG-------PPPGAPPPAPHVNPAFFPPPTNS---------GMPTSDSRGP 378
           + L   PH P        P PGA PP+     + + PPT +         G+P       
Sbjct: 139 IPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRK 198

Query: 379 PPTDPYGRPPPYDRGDYG 396
           PP  P G PPP     YG
Sbjct: 199 PPGPPPGPPPPQVVQMYG 216



 Score = 32.7 bits (73), Expect = 0.89
 Identities = 22/47 (46%), Positives = 24/47 (51%), Gaps = 10/47 (21%)

Query: 233 GQTPPRPPLG--PPGPPGPPGPPPP------GQVLPPPLAGPPNRGD 271
           G   PR P G  PPGPP  PGPPPP      G+ +   L  PP R D
Sbjct: 187 GHGVPRLPPGRKPPGPP--PGPPPPQVVQMYGRKVGFALDLPPRRRD 231



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 27/72 (37%), Positives = 29/72 (40%), Gaps = 19/72 (26%)

Query: 223 PGGPPPPF---PAGQTPPR------PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRP 273
           PG  PP      +   PP       P LG   P  PPG  PPG   PPP  GPP     P
Sbjct: 159 PGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPG---PPP--GPP-----P 208

Query: 274 PPPVLFPGQPFG 285
           P  V   G+  G
Sbjct: 209 PQVVQMYGRKVG 220


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score =  120 bits (301), Expect = 3e-27
 Identities = 87/196 (44%), Positives = 91/196 (46%), Gaps = 38/196 (19%)

Query: 211 VPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGP-PG------PP--PPGQVLPP 261
           VP     PG +G   PPPP P   T P PP  PP PP P PG      PP  P G  + P
Sbjct: 573 VPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISP 632

Query: 262 PLAGPPNRGDR--PPPPVLFPGQPFGQPPLGPLPPG----PPPPVPGYGPPPGPPPPQQG 315
           P   PP  GD   PPPP L  G   G P    LP G    PPPP+PG    P PPPP  G
Sbjct: 633 P---PPLSGDATIPPPPPLPEG--VGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPG 687

Query: 316 P---PPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHV-NPAFFPPPTNSGMP 371
               PPPP P P    G  G P    PPP LPG  PG PPP P    P   PPP   GMP
Sbjct: 688 SAGIPPPPPPLP----GEAGMP---PPPPPLPG-GPGIPPPPPFPGGPGIPPPPPGMGMP 739

Query: 372 TSDSRGPPPTDPYGRP 387
                 PPP   +G P
Sbjct: 740 ------PPPPFGFGVP 749



 Score =  107 bits (266), Expect = 4e-23
 Identities = 93/291 (31%), Positives = 117/291 (40%), Gaps = 31/291 (10%)

Query: 110 LEIKFFENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEM 169
           L+++  +  ++ + K   L G      S+K      K++L  +   +T    +   + E 
Sbjct: 489 LQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELED 548

Query: 170 QSRKTTQSGQMSGEGKAGPPGGSSRAAFPQ-----GGRGRGRFPGAVPGGDRFPGPAGPG 224
             +   +   +S      PP   SRA  P      G  G    P   PG    P P  P 
Sbjct: 549 AKK---EMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPP 605

Query: 225 GPPP-PFPAGQTPPRPPLGPPGPPGPPGPPPPGQ-VLPPPLAGPPNRGDRPPPPVLFPGQ 282
            PPP P P G     PP  P G    P PP  G   +PPP   P   G   P P   PG 
Sbjct: 606 PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP--PPLPEGVGIPSPSSLPGG 663

Query: 283 PFGQPPLGPLP-----PGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTL 337
               PP  PLP     P PPPP+PG    P PPPP  G    P P PP P GP      +
Sbjct: 664 T-AIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGP-----GI 717

Query: 338 APPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPP 388
            PPP  PG  PG PPP P +     PPP   G+P +      P  P+G  P
Sbjct: 718 PPPPPFPG-GPGIPPPPPGMGMP-PPPPFGFGVPAA------PVLPFGLTP 760



 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 66/166 (39%), Positives = 70/166 (42%), Gaps = 26/166 (15%)

Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-PGG----PPPPFPAGQTP 236
           G   + PP  S  A  P         P  +P G   P P+  PGG    PPPP P     
Sbjct: 627 GTAISPPPPLSGDATIPP--------PPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARI 678

Query: 237 PRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGP 296
           P PP   P  PG  G PPP    PPPL   P     PPPP   PG P G PP  P P GP
Sbjct: 679 PPPP---PPLPGSAGIPPP----PPPL---PGEAGMPPPPPPLPGGP-GIPPPPPFPGGP 727

Query: 297 --PPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPP 340
             PPP PG G PP PP     P  P  PF   P     P + L  P
Sbjct: 728 GIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRP 773



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 47/130 (36%), Positives = 55/130 (42%), Gaps = 15/130 (11%)

Query: 283 PFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPH 342
           P   P   P+PP PP P       P PP P     PPP P PP PP PL   + ++ PP 
Sbjct: 564 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPS 623

Query: 343 LPGPPPGAPPPAPHVNPAFFPP----------PTNSGMPTSDSRGPPPTDPYGR----PP 388
           LPG    +PPP P    A  PP          P+ S +P   +  PPP  P       PP
Sbjct: 624 LPGGTAISPPP-PLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 682

Query: 389 PYDRGDYGPP 398
           P   G  G P
Sbjct: 683 PPLPGSAGIP 692



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 27/73 (36%), Positives = 31/73 (42%), Gaps = 8/73 (10%)

Query: 340 PPHLPG--PPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRG--DY 395
           PP +P   P P A PP P  +    PPP   G  T+    PPP  P   PPP   G    
Sbjct: 564 PPSVPSRAPVPPA-PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPP---PPPLPGGVCIS 619

Query: 396 GPPGREMDTARTP 408
            PP     TA +P
Sbjct: 620 SPPSLPGGTAISP 632


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score =  120 bits (301), Expect = 3e-27
 Identities = 87/196 (44%), Positives = 91/196 (46%), Gaps = 38/196 (19%)

Query: 211 VPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGP-PG------PP--PPGQVLPP 261
           VP     PG +G   PPPP P   T P PP  PP PP P PG      PP  P G  + P
Sbjct: 582 VPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISP 641

Query: 262 PLAGPPNRGDR--PPPPVLFPGQPFGQPPLGPLPPG----PPPPVPGYGPPPGPPPPQQG 315
           P   PP  GD   PPPP L  G   G P    LP G    PPPP+PG    P PPPP  G
Sbjct: 642 P---PPLSGDATIPPPPPLPEG--VGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPG 696

Query: 316 P---PPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHV-NPAFFPPPTNSGMP 371
               PPPP P P    G  G P    PPP LPG  PG PPP P    P   PPP   GMP
Sbjct: 697 SAGIPPPPPPLP----GEAGMP---PPPPPLPG-GPGIPPPPPFPGGPGIPPPPPGMGMP 748

Query: 372 TSDSRGPPPTDPYGRP 387
                 PPP   +G P
Sbjct: 749 ------PPPPFGFGVP 758



 Score =  107 bits (266), Expect = 4e-23
 Identities = 93/291 (31%), Positives = 117/291 (40%), Gaps = 31/291 (10%)

Query: 110 LEIKFFENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEM 169
           L+++  +  ++ + K   L G      S+K      K++L  +   +T    +   + E 
Sbjct: 498 LQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELED 557

Query: 170 QSRKTTQSGQMSGEGKAGPPGGSSRAAFPQ-----GGRGRGRFPGAVPGGDRFPGPAGPG 224
             +   +   +S      PP   SRA  P      G  G    P   PG    P P  P 
Sbjct: 558 AKK---EMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPP 614

Query: 225 GPPP-PFPAGQTPPRPPLGPPGPPGPPGPPPPGQ-VLPPPLAGPPNRGDRPPPPVLFPGQ 282
            PPP P P G     PP  P G    P PP  G   +PPP   P   G   P P   PG 
Sbjct: 615 PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP--PPLPEGVGIPSPSSLPGG 672

Query: 283 PFGQPPLGPLP-----PGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTL 337
               PP  PLP     P PPPP+PG    P PPPP  G    P P PP P GP      +
Sbjct: 673 T-AIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGP-----GI 726

Query: 338 APPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPP 388
            PPP  PG  PG PPP P +     PPP   G+P +      P  P+G  P
Sbjct: 727 PPPPPFPG-GPGIPPPPPGMGMP-PPPPFGFGVPAA------PVLPFGLTP 769



 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 66/166 (39%), Positives = 70/166 (42%), Gaps = 26/166 (15%)

Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-PGG----PPPPFPAGQTP 236
           G   + PP  S  A  P         P  +P G   P P+  PGG    PPPP P     
Sbjct: 636 GTAISPPPPLSGDATIPP--------PPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARI 687

Query: 237 PRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGP 296
           P PP   P  PG  G PPP    PPPL   P     PPPP   PG P G PP  P P GP
Sbjct: 688 PPPP---PPLPGSAGIPPP----PPPL---PGEAGMPPPPPPLPGGP-GIPPPPPFPGGP 736

Query: 297 --PPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPP 340
             PPP PG G PP PP     P  P  PF   P     P + L  P
Sbjct: 737 GIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRP 782



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 47/130 (36%), Positives = 55/130 (42%), Gaps = 15/130 (11%)

Query: 283 PFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPH 342
           P   P   P+PP PP P       P PP P     PPP P PP PP PL   + ++ PP 
Sbjct: 573 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPS 632

Query: 343 LPGPPPGAPPPAPHVNPAFFPP----------PTNSGMPTSDSRGPPPTDPYGR----PP 388
           LPG    +PPP P    A  PP          P+ S +P   +  PPP  P       PP
Sbjct: 633 LPGGTAISPPP-PLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 691

Query: 389 PYDRGDYGPP 398
           P   G  G P
Sbjct: 692 PPLPGSAGIP 701



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 27/73 (36%), Positives = 31/73 (42%), Gaps = 8/73 (10%)

Query: 340 PPHLPG--PPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRG--DY 395
           PP +P   P P A PP P  +    PPP   G  T+    PPP  P   PPP   G    
Sbjct: 573 PPSVPSRAPVPPA-PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPP---PPPLPGGVCIS 628

Query: 396 GPPGREMDTARTP 408
            PP     TA +P
Sbjct: 629 SPPSLPGGTAISP 641


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score =  119 bits (297), Expect = 9e-27
 Identities = 93/233 (39%), Positives = 99/233 (42%), Gaps = 43/233 (18%)

Query: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPG---GPPPP--FPAGQTPPR---- 238
           PP G      PQGG  + + P   PG    P P G     GPPP    P GQ P      
Sbjct: 52  PPPGKPEGRPPQGGN-QSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQS 110

Query: 239 --PPLGPPGPPGPP--------GPPP-PGQVL-PPPLAGPPNRGDRPPPPVLFPGQPFGQ 286
             PP  P  P GPP        GPPP PG+   PPP  G  N+   PPP    PG+P G 
Sbjct: 111 QGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGG--NQSQGPPPR---PGKPEGP 165

Query: 287 PPLGPLPPGPPPPVPG--YGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLP 344
           PP G      PPP PG   GPPP      QGPPP PG   P  P P G   +  PPP  P
Sbjct: 166 PPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPG--KPEGPPPQGGNQSQGPPPR-P 222

Query: 345 GPPPGAPP--------PAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389
           G P G P         P PH      PPP     P    R PPP  P G PPP
Sbjct: 223 GKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKP---QRPPPPGRPQGPPPP 272



 Score =  118 bits (295), Expect = 2e-26
 Identities = 96/239 (40%), Positives = 106/239 (44%), Gaps = 51/239 (21%)

Query: 187 GPP---GGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP--PPFPAGQTPPRPPL 241
           GPP   G  S+   P+ G+  G+ P    GG++  GP    G P  PP   G     PP 
Sbjct: 80  GPPPQGGNQSQGPPPRPGKPEGQPP---QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPP 136

Query: 242 GPPGPPGPP--------GPPP-PGQVL-PPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGP 291
            P  P GPP        GPPP PG+   PPP  G  N+   PPP    PG+P G PP G 
Sbjct: 137 RPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGG--NQSQGPPP---HPGKPEGPPPQGG 191

Query: 292 LPPGPPPPVPG--YGPPP-------GPP--------PPQQGPPPPPGPFPPRPPGPLGPP 334
                PPP PG   GPPP       GPP        PP QG   P GP PP P  P GPP
Sbjct: 192 NQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGP-PPHPGKPQGPP 250

Query: 335 LTLAPPPHLPGPPPGAP--PPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP--PP 389
                 P  P PPPG P  PP P  NP    PP     P    +GPPP    GRP  PP
Sbjct: 251 PQEGNKPQRP-PPPGRPQGPPPPGGNPQQPLPP-----PAGKPQGPPPPPQGGRPHRPP 303



 Score =  115 bits (287), Expect = 1e-25
 Identities = 82/219 (37%), Positives = 93/219 (42%), Gaps = 27/219 (12%)

Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPL 241
           G+ +  PP G +++  P    G+   P    G      P  PG P  P P G    + P 
Sbjct: 97  GKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGP- 155

Query: 242 GPPGPPGPPGPPPPG---QVLPPPLAG-----PPNRGDRPPPPVLFPGQPFGQPPLG--- 290
            PP P  P GPPP G      PPP  G     PP  G++   P   PG+P G PP G   
Sbjct: 156 -PPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 214

Query: 291 ----PLPPGPP--PPVPGYGPPPGPPP---PQQGPPPPPGPFPPRPPGPLGPPLTLAPPP 341
               P  PG P  PP  G   P GPPP     QGPPP  G  P RPP P  P     PPP
Sbjct: 215 SQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQ---GPPP 271

Query: 342 HLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP 380
             PG  P  P P P   P   PPP   G P    +G PP
Sbjct: 272 --PGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPP 308



 Score =  113 bits (283), Expect = 4e-25
 Identities = 87/235 (37%), Positives = 98/235 (41%), Gaps = 48/235 (20%)

Query: 212 PGGDRFPGPAGPGGPPPPFPAGQTPPRPPLG-------PPGPPGPPGPPPPG---QVLPP 261
           P G R  G   P   PPP   G+   RPP G       PP P  P GPPP G      PP
Sbjct: 36  PEGRRPQGGNQPQRTPPP--PGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPP 93

Query: 262 PLAG-----PPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPG--YGPPPGPPPPQQ 314
           P  G     PP  G++   P   PG+P G PP G      PPP PG   GPPP      Q
Sbjct: 94  PRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ 153

Query: 315 GPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPP--------PAPHVNPAFFPPPT 366
           GPPP PG   P  P P G   +  PPPH PG P G PP        P P       PPP 
Sbjct: 154 GPPPRPG--KPEGPPPQGGNQSQGPPPH-PGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQ 210

Query: 367 NSGMPTSDSRGPPP-------------TDPYGRPPPYDRGDYGPPGREMDTARTP 408
                 + S+GPPP               P G PPP+     GPP +E +  + P
Sbjct: 211 GG----NQSQGPPPRPGKPEGPPSQGGNKPQG-PPPHPGKPQGPPPQEGNKPQRP 260



 Score =  109 bits (273), Expect = 6e-24
 Identities = 85/233 (36%), Positives = 98/233 (42%), Gaps = 25/233 (10%)

Query: 183 EGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-PGGPPPPFPAGQTPPRPPL 241
           EG+    G   +   P  G+  GR P    GG++  GP   PG P  P P G    + P 
Sbjct: 37  EGRRPQGGNQPQRTPPPPGKPEGRPP---QGGNQSQGPPPRPGKPEGPPPQGGNQSQGP- 92

Query: 242 GPPGPPGPPGPPPPG---QVLPPPLAG-----PPNRGDRPPPPVLFPGQPFGQPPLGPLP 293
            PP P  P G PP G      PPP  G     PP  G++   P   PG+P G PP G   
Sbjct: 93  -PPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 151

Query: 294 PGPPPPVPGY--GPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAP 351
              PPP PG   GPPP      QGPPP PG   P  P P G   +  PPP  PG P G P
Sbjct: 152 SQGPPPRPGKPEGPPPQGGNQSQGPPPHPGK--PEGPPPQGGNQSQGPPPR-PGKPEGPP 208

Query: 352 PPAPHVNPAFFPPPTNSGMPTSDS----RGPPPTD--PYGRPPPYDRGDYGPP 398
           P   + +    P P     P S      +GPPP    P G PP        PP
Sbjct: 209 PQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPP 261



 Score =  105 bits (261), Expect = 1e-22
 Identities = 77/200 (38%), Positives = 85/200 (42%), Gaps = 34/200 (17%)

Query: 228 PPFPAGQTPPRPPLG-------PPGPPGPPGPPPPG---QVLPPPLAG-----PPNRGDR 272
           P   +G+   R P G       PP P  P G PP G      PPP  G     PP  G++
Sbjct: 29  PSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 88

Query: 273 PPPPVLFPGQPFGQPPLGPLPPGPPPPVPG--YGPPPGPPPPQQGPPPPPGPFPPRPPGP 330
              P   PG+P GQPP G      PPP PG   GPPP      QGPPP PG   P  P P
Sbjct: 89  SQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPG--KPEGPPP 146

Query: 331 LGPPLTLAPPPHLPGPPPGAPP--------PAPHVNPAFFPPPTNSGMPTSDSRGPPPT- 381
            G   +  PPP  PG P G PP        P PH      PPP       + S+GPPP  
Sbjct: 147 QGGNQSQGPPPR-PGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGG----NQSQGPPPRP 201

Query: 382 -DPYGRPPPYDRGDYGPPGR 400
             P G PP       GPP R
Sbjct: 202 GKPEGPPPQGGNQSQGPPPR 221


>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
           preproprotein [Homo sapiens]
          Length = 198

 Score =  112 bits (279), Expect = 1e-24
 Identities = 80/195 (41%), Positives = 86/195 (44%), Gaps = 39/195 (20%)

Query: 208 PGAVPGGDRFPGPAG---PGGPPPPFPAGQTPPRPPLGPPGPPG--PPGPPPPGQVLPPP 262
           P  + G  + P P G   P GPPPP       P  P GPP   G  P GPPPPG+   PP
Sbjct: 29  PSLIAGNPQGPSPQGGNKPQGPPPP-------PGKPQGPPPQGGNKPQGPPPPGKPQGPP 81

Query: 263 LAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPP--QQGPPPPP 320
             G  +R  R PP     G+P G PP G  P GPPP   G   P GPPPP   QGPP   
Sbjct: 82  PQGDKSRSPRSPP-----GKPQGPPPQGGKPQGPPP--QGGNKPQGPPPPGKPQGPPAQG 134

Query: 321 G---PFPPRPPG-PLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSR 376
           G        PPG P GPP      P  P PP G  P  P   PA        G P    +
Sbjct: 135 GSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPA--------GQP----Q 182

Query: 377 GPPPTDPYGRP--PP 389
           GPP     GRP  PP
Sbjct: 183 GPPRPPQGGRPSRPP 197



 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 64/153 (41%), Positives = 72/153 (47%), Gaps = 16/153 (10%)

Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPP-PFPAGQTPPRPP 240
           G+ +  PP G ++   PQG    G+  G  P GD+   P  P G P  P P G  P  PP
Sbjct: 55  GKPQGPPPQGGNK---PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPP 111

Query: 241 LGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPL-GPLPPGPPPP 299
             P G   P GPPPPG+   PP  G         PP    G+P G P   G  P GPPPP
Sbjct: 112 --PQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPP----GKPQGPPQQEGNNPQGPPPP 165

Query: 300 VPGYGP--PPGPPPPQ-QGPP-PPPGPFPPRPP 328
             G  P  P  PP  Q QGPP PP G  P RPP
Sbjct: 166 A-GGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 197



 Score = 80.5 bits (197), Expect = 4e-15
 Identities = 58/154 (37%), Positives = 63/154 (40%), Gaps = 30/154 (19%)

Query: 249 PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGP-LPPGPPPPVPGYGPPP 307
           P GP P G           N+   PPPP   PG+P G PP G   P GPPPP    G P 
Sbjct: 36  PQGPSPQGG----------NKPQGPPPP---PGKPQGPPPQGGNKPQGPPPP----GKPQ 78

Query: 308 GPPPP---QQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPP 364
           GPPP     + P  PPG  P  PP   G P    PPP     P G PPP     P     
Sbjct: 79  GPPPQGDKSRSPRSPPGK-PQGPPPQGGKPQ--GPPPQGGNKPQGPPPPGKPQGP----- 130

Query: 365 PTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPP 398
           P   G  +  +R PP   P G P        GPP
Sbjct: 131 PAQGGSKSQSARSPPGK-PQGPPQQEGNNPQGPP 163



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 48/122 (39%), Positives = 54/122 (44%), Gaps = 28/122 (22%)

Query: 304 GPPPGPPPP----QQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPP------ 353
           G P GP P      QGPPPPPG   P+ P P G      PPP  PG P   PPP      
Sbjct: 34  GNPQGPSPQGGNKPQGPPPPPGK--PQGPPPQGGNKPQGPPP--PGKPQ-GPPPQGDKSR 88

Query: 354 APHVNPAF-FPPPTNSGMPTSDSRGPPP---TDPYGRPPPYDRGDYGPP---GREMDTAR 406
           +P   P     PP   G P    +GPPP     P G PPP      GPP   G +  +AR
Sbjct: 89  SPRSPPGKPQGPPPQGGKP----QGPPPQGGNKPQGPPPP--GKPQGPPAQGGSKSQSAR 142

Query: 407 TP 408
           +P
Sbjct: 143 SP 144



 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 38/115 (33%), Positives = 45/115 (39%), Gaps = 30/115 (26%)

Query: 170 QSRKTTQSGQMSGEGKAGPP-GGSSRAAFPQGG-RGRGRFPGAVPGGDRFPG-------- 219
           Q  K+       G+ +  PP GG  +   PQGG + +G  P   P G    G        
Sbjct: 83  QGDKSRSPRSPPGKPQGPPPQGGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSAR 142

Query: 220 --PAGPGGPP---------PPFPAGQTPPRP-------PLGPPGPP--GPPGPPP 254
             P  P GPP         PP PAG  P +P       P GPP PP  G P  PP
Sbjct: 143 SPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 197



 Score = 32.7 bits (73), Expect = 0.89
 Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 16/78 (20%)

Query: 334 PLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP---TDPYGRPPPY 390
           P  +A  P  P P  G  P  P       PPP   G P    +GPPP     P G PPP 
Sbjct: 29  PSLIAGNPQGPSPQGGNKPQGP-------PPPP--GKP----QGPPPQGGNKPQGPPPPG 75

Query: 391 DRGDYGPPGREMDTARTP 408
                 P G +  + R+P
Sbjct: 76  KPQGPPPQGDKSRSPRSP 93


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score =  110 bits (274), Expect = 4e-24
 Identities = 86/234 (36%), Positives = 98/234 (41%), Gaps = 34/234 (14%)

Query: 185 KAGPPGGSSRAAFPQGGRGRG-----RFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRP 239
           + G  GG  R     GG GRG     R P    G ++  GP GPG        GQ+ P+P
Sbjct: 9   RGGGGGGFHRRG---GGGGRGGLHDFRSPPPGMGLNQNRGPMGPG-------PGQSGPKP 58

Query: 240 PLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPP 299
           P+ PP P      PPP Q  PPP   PP++    PPP   P Q   QPP  P P     P
Sbjct: 59  PIPPPPPHQQQQQPPPQQ--PPPQQPPPHQ----PPPHPQPHQQ-QQPP--PPPQDSSKP 109

Query: 300 VPGYGPPPGP-----PPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPA 354
           V   GP P P     PP     PP   P    PPG  GP  T  PPP +   PPGAPPP 
Sbjct: 110 VVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGS-GPGPTPTPPPAVTSAPPGAPPPT 168

Query: 355 PHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTP 408
           P  +     PP   G P   +  P P    G  P    G  GP G +M     P
Sbjct: 169 PPSSGVPTTPPQAGGPPPPPAAVPGP----GPGPKQGPGPGGPKGGKMPGGPKP 218



 Score =  105 bits (261), Expect = 1e-22
 Identities = 86/258 (33%), Positives = 91/258 (35%), Gaps = 53/258 (20%)

Query: 178 GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPP 237
           G     G  G  GG      P  G G  +  G +  G    GP  P  PPPP    Q PP
Sbjct: 14  GGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPP 73

Query: 238 R---PPLGPPGPPGPPGPPPPGQVLPPP----------LAGP---PNRGDRPP------- 274
               PP  PP    PP P P  Q  PPP            GP   P  G  PP       
Sbjct: 74  PQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPP 133

Query: 275 --------PPVLFPGQ-PFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPP----- 320
                   PP   PG  P   P +   PPG PPP P     P  PP   GPPPPP     
Sbjct: 134 ATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPG 193

Query: 321 -GPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMP-------- 371
            GP P + PGP GP     P    PG  PG   P  H      PP    G P        
Sbjct: 194 PGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPK----PPHRGGGEPRGGRQHHP 249

Query: 372 ---TSDSRGPPPTDPYGR 386
                  +GPPP  P GR
Sbjct: 250 PYHQQHHQGPPPGGPGGR 267


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score =  108 bits (271), Expect = 1e-23
 Identities = 92/265 (34%), Positives = 104/265 (39%), Gaps = 65/265 (24%)

Query: 190 GGSSRAAFPQGGRGRGRFPGAVPGGD-RFPGPAGPG---GPPPPFPAGQTPPRPPLGPPG 245
           GGS     P GGR     P + P G  RFP P+ PG   GPP P      PPRP +G   
Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPS-PGHRSGPPEPQRNRMPPPRPDVGSKP 180

Query: 246 ---PPGPPGPPPPGQVLP-----PPLAGPPNRGDRPPPPVLFPGQ--------------- 282
              PP  P  P P Q  P     PP+ G P +    P P  FPG                
Sbjct: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL 240

Query: 283 ----PFG-QPPLGPLPPG-----PPPPVPGYGPPPG-------PPPPQQGPPPPPGPFPP 325
               PF  +PPL P P       PPPP P  G  P        PPPPQ   PP P    P
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300

Query: 326 RPPGPLGPPLTLAPPPHLPGPPPGAPP----------PAPHVNPAFFPPPTNSGMPTSDS 375
                  PP    PPP  PGPPP  P           P  +++ +   PP    +P+   
Sbjct: 301 SASSQAPPP---PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPP----LPSPGR 353

Query: 376 RGPPPTDPYGRPPPYDRGDYGPPGR 400
            GP P  P  RPPP  R    PPGR
Sbjct: 354 SGPLPPPPSERPPPPVR---DPPGR 375



 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 93/303 (30%), Positives = 110/303 (36%), Gaps = 66/303 (21%)

Query: 144 LPKRELHGQNPVVTPCNK-QFLSQFEMQSRKTTQSGQMSGEGKAGPPGG-SSRAAFPQGG 201
           L K E  G+N +++  +K + L +     R      +  G G  G  GG      F  GG
Sbjct: 25  LNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDKPKGAGAGGGGGGFGGGGGFGGGG 84

Query: 202 RGRGRFPGAVPGGDRFPGPAG------------------PGGPPPPF--PAGQTPPRPPL 241
            G G   G   GG   PG  G                   GG  PP   P G++    P 
Sbjct: 85  GGGG---GGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPF 141

Query: 242 GPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGP----- 296
            PP  PG    P PG    PP    P R   PPP      +P   PP  P  P P     
Sbjct: 142 SPPSGPGRFPVPSPGHRSGPP---EPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP 198

Query: 297 ----PPPVPG--YGPPPGPPPP---------------QQGPPPPPGPFPPRPPGPLGPPL 335
                PPVPG    P PGP PP               +Q P     PF  RPP P  P  
Sbjct: 199 HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSR 258

Query: 336 TLAPPPHLPGPPPG---------APPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGR 386
            L   P  P PP G          PPP P  N    PP  ++  P++ S+ PPP  P  R
Sbjct: 259 ALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK---PPVPSTPRPSASSQAPPPPPPPSR 315

Query: 387 PPP 389
           P P
Sbjct: 316 PGP 318



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 72/213 (33%), Positives = 80/213 (37%), Gaps = 55/213 (25%)

Query: 204 RGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQV----- 258
           R   P   P  ++ P P+     P P  + Q PP PP  PP  PGPP  PP         
Sbjct: 279 REAVPPPPPQNNKPPVPS----TPRPSASSQAPPPPP--PPSRPGPPPLPPSSSGNDETP 332

Query: 259 -LP----------PPLAGPPNRGDRPPPPVLFPGQPFGQPP--LGPLPPGPPPPVPGYGP 305
            LP          PPL  P   G  PPPP   P  P   PP   GPLP  PPPPV   G 
Sbjct: 333 RLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLP--PPPPVSRNGS 390

Query: 306 -----PPGPPPPQQG--PPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVN 358
                P  P  P +     P  GP PP PP     P   APPP         PPP+  + 
Sbjct: 391 TSRALPATPQLPSRSGVDSPRSGPRPPLPP---DRPSAGAPPP---------PPPSTSIR 438

Query: 359 PAFFPPPTNSGM-------PTSDSRGPPPTDPY 384
             F   P            P SD    PP +PY
Sbjct: 439 NGFQDSPCEDEWESRFYFHPISDL---PPPEPY 468


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score =  108 bits (271), Expect = 1e-23
 Identities = 92/265 (34%), Positives = 104/265 (39%), Gaps = 65/265 (24%)

Query: 190 GGSSRAAFPQGGRGRGRFPGAVPGGD-RFPGPAGPG---GPPPPFPAGQTPPRPPLGPPG 245
           GGS     P GGR     P + P G  RFP P+ PG   GPP P      PPRP +G   
Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPS-PGHRSGPPEPQRNRMPPPRPDVGSKP 180

Query: 246 ---PPGPPGPPPPGQVLP-----PPLAGPPNRGDRPPPPVLFPGQ--------------- 282
              PP  P  P P Q  P     PP+ G P +    P P  FPG                
Sbjct: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL 240

Query: 283 ----PFG-QPPLGPLPPG-----PPPPVPGYGPPPG-------PPPPQQGPPPPPGPFPP 325
               PF  +PPL P P       PPPP P  G  P        PPPPQ   PP P    P
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300

Query: 326 RPPGPLGPPLTLAPPPHLPGPPPGAPP----------PAPHVNPAFFPPPTNSGMPTSDS 375
                  PP    PPP  PGPPP  P           P  +++ +   PP    +P+   
Sbjct: 301 SASSQAPPP---PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPP----LPSPGR 353

Query: 376 RGPPPTDPYGRPPPYDRGDYGPPGR 400
            GP P  P  RPPP  R    PPGR
Sbjct: 354 SGPLPPPPSERPPPPVR---DPPGR 375



 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 93/303 (30%), Positives = 110/303 (36%), Gaps = 66/303 (21%)

Query: 144 LPKRELHGQNPVVTPCNK-QFLSQFEMQSRKTTQSGQMSGEGKAGPPGG-SSRAAFPQGG 201
           L K E  G+N +++  +K + L +     R      +  G G  G  GG      F  GG
Sbjct: 25  LNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDKPKGAGAGGGGGGFGGGGGFGGGG 84

Query: 202 RGRGRFPGAVPGGDRFPGPAG------------------PGGPPPPF--PAGQTPPRPPL 241
            G G   G   GG   PG  G                   GG  PP   P G++    P 
Sbjct: 85  GGGG---GGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPF 141

Query: 242 GPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGP----- 296
            PP  PG    P PG    PP    P R   PPP      +P   PP  P  P P     
Sbjct: 142 SPPSGPGRFPVPSPGHRSGPP---EPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP 198

Query: 297 ----PPPVPG--YGPPPGPPPP---------------QQGPPPPPGPFPPRPPGPLGPPL 335
                PPVPG    P PGP PP               +Q P     PF  RPP P  P  
Sbjct: 199 HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSR 258

Query: 336 TLAPPPHLPGPPPG---------APPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGR 386
            L   P  P PP G          PPP P  N    PP  ++  P++ S+ PPP  P  R
Sbjct: 259 ALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK---PPVPSTPRPSASSQAPPPPPPPSR 315

Query: 387 PPP 389
           P P
Sbjct: 316 PGP 318



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 72/213 (33%), Positives = 80/213 (37%), Gaps = 55/213 (25%)

Query: 204 RGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQV----- 258
           R   P   P  ++ P P+     P P  + Q PP PP  PP  PGPP  PP         
Sbjct: 279 REAVPPPPPQNNKPPVPS----TPRPSASSQAPPPPP--PPSRPGPPPLPPSSSGNDETP 332

Query: 259 -LP----------PPLAGPPNRGDRPPPPVLFPGQPFGQPP--LGPLPPGPPPPVPGYGP 305
            LP          PPL  P   G  PPPP   P  P   PP   GPLP  PPPPV   G 
Sbjct: 333 RLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLP--PPPPVSRNGS 390

Query: 306 -----PPGPPPPQQG--PPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVN 358
                P  P  P +     P  GP PP PP     P   APPP         PPP+  + 
Sbjct: 391 TSRALPATPQLPSRSGVDSPRSGPRPPLPP---DRPSAGAPPP---------PPPSTSIR 438

Query: 359 PAFFPPPTNSGM-------PTSDSRGPPPTDPY 384
             F   P            P SD    PP +PY
Sbjct: 439 NGFQDSPCEDEWESRFYFHPISDL---PPPEPY 468


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score =  108 bits (271), Expect = 1e-23
 Identities = 95/264 (35%), Positives = 103/264 (39%), Gaps = 55/264 (20%)

Query: 161 KQFLSQFEMQSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGP 220
           KQF  QF  +  K              PP   S  A P G +   R P  +  G   P P
Sbjct: 204 KQFFLQFHFKMEK--------------PPAPPSLPAGPPGVK---RPPPPLMNGLP-PRP 245

Query: 221 AGPGGPPPPFPAG-QTPPRPPLGPPGPPGPPGPP----------PPGQVLPPPLAG--PP 267
             P   PPP P G   PP PP GP  P GPPGPP          PP  V+ PP +G  PP
Sbjct: 246 PLPESLPPPPPGGLPLPPMPPTGP-APSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPP 304

Query: 268 NRGDRPPPPVLFPGQPFGQPPLG---PLPPGPPPPVPGYGPP-PGPPPPQQGP-PPPPGP 322
             G  PP P + P  P   PP     P  PG  PP PG  PP PG  PP  G  PP PG 
Sbjct: 305 APGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGV 364

Query: 323 FPPRPPG--PLGPPLTLAPP---PHLPGPPPGAP------------PPAPHVN-PAFFPP 364
            PP   G  P  P +  A P   P  PG  P AP            PP  H + P   P 
Sbjct: 365 HPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQ 424

Query: 365 PTNSGMPTSDSRGPPPTDPYGRPP 388
           P            P P  P  RPP
Sbjct: 425 PPGVHPSNPGVHPPTPMPPMLRPP 448



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 55/135 (40%), Positives = 60/135 (44%), Gaps = 31/135 (22%)

Query: 271 DRPPPPVLFPGQPFGQPPLGPLPPG---PPPPVPGYGPPPGPPPPQQGPPPPPG-----P 322
           ++PP P   P  P G       PPG   PPPP+   G PP PP P+  PPPPPG     P
Sbjct: 215 EKPPAP---PSLPAG-------PPGVKRPPPPLMN-GLPPRPPLPESLPPPPPGGLPLPP 263

Query: 323 FPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNP---AFFPPPTNSGMPTSDSRGP- 378
            PP  P P GPP     PP LP P PG  PPAP V+P      PP      P      P 
Sbjct: 264 MPPTGPAPSGPP----GPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPA 319

Query: 379 ----PPTDPYGRPPP 389
               PPT     P P
Sbjct: 320 PGVHPPTSGVHPPAP 334



 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 65/164 (39%), Positives = 70/164 (42%), Gaps = 30/164 (18%)

Query: 208 PGAVPGGDRFPGPAGPGGPP-----PPFPAGQTPPRPPLGPPGP---PGPPG--PPPPGQ 257
           PG  P       PA    PP     PP P G  PP P + PP P   P  PG  PP PG 
Sbjct: 306 PGVHPPAPGVHPPAPGVHPPTSGVHPPAP-GVHPPAPGVHPPAPGVHPPAPGVHPPAPG- 363

Query: 258 VLPPPLAG--PPNRGDRPPPPVLFPGQPFGQPP----------LGPLPPGPPPPVPGYGP 305
           V PPP AG  P   G  P  P + P  P   PP          + P PPG  P  PG  P
Sbjct: 364 VHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHP 423

Query: 306 -PPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPP 348
            PPG  P   G  PP  P PP     L PPL    P ++P PPP
Sbjct: 424 QPPGVHPSNPGVHPPT-PMPPM----LRPPLPSEGPGNIPPPPP 462



 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 64/171 (37%), Positives = 71/171 (41%), Gaps = 37/171 (21%)

Query: 246 PPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGP 305
           PP PP  P          AGPP    RPPPP++      G PP  PLP   PPP PG  P
Sbjct: 217 PPAPPSLP----------AGPPGV-KRPPPPLMN-----GLPPRPPLPESLPPPPPGGLP 260

Query: 306 PPGPPPPQQGPPPPPGP-----FPPRPPGPLGPPLTLAPPPHLPGPP-PGAPPPAPHVNP 359
            P  PP     P P GP      PP  PG   P   + PP     PP PG  PPAP V+P
Sbjct: 261 LPPMPPTG---PAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHP 317

Query: 360 AF--FPPPTNSGMPTSDSRGPP-----PTDPYGRPP-----PYDRGDYGPP 398
                 PPT+   P +    PP     P  P   PP     P   G + PP
Sbjct: 318 PAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPP 368



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 29/77 (37%), Positives = 30/77 (38%), Gaps = 18/77 (23%)

Query: 324 PPRPPG-PLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTD 382
           PP PP  P GPP    PPP L    P  PP      P   PPP   G+P       PPT 
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMNGLPPRPPL-----PESLPPPPPGGLPLPPM---PPTG 268

Query: 383 PYGRPPPYDRGDYGPPG 399
           P            GPPG
Sbjct: 269 P---------APSGPPG 276


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score =  108 bits (270), Expect = 1e-23
 Identities = 86/228 (37%), Positives = 93/228 (40%), Gaps = 36/228 (15%)

Query: 191 GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPG---GPPPPFPAGQTPPRPPLG----- 242
           G      PQGG    R P   PG  + P P G     GPPPP   G+   RPP G     
Sbjct: 34  GKPEGRRPQGGNQPQR-PPPPPGKPQGPPPQGGNQSQGPPPP--PGKPEGRPPQGGNQSQ 90

Query: 243 -PPGPPGPPGPPPP-----GQVLPPPLAGPP-------NRGDRPPPPVLFPGQPFGQPPL 289
            PP  PG P  PPP      Q  PPP   P        N+  RPPPP   PG+P   PP 
Sbjct: 91  GPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPP---PGKPERPPPQ 147

Query: 290 GPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPG 349
           G      PPP PG    P  PPPQ+G        PP    P GPP      P  P PPPG
Sbjct: 148 GGNQSQGPPPHPG---KPEGPPPQEGNKSRSARSPPGK--PQGPPQQEGNKPQGP-PPPG 201

Query: 350 APPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGP 397
            P   P   PA   P      P    +GPPP    GRPP   +G   P
Sbjct: 202 KPQGPP---PAGGNPQQPQAPPAGKPQGPPPPPQGGRPPRPAQGQQPP 246



 Score = 99.8 bits (247), Expect = 6e-21
 Identities = 74/185 (40%), Positives = 84/185 (45%), Gaps = 37/185 (20%)

Query: 232 AGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGP 291
           +G+   R P G   P  PP  PPPG+   PP  G  N+   PPPP   PG+P G+PP G 
Sbjct: 33  SGKPEGRRPQGGNQPQRPP--PPPGKPQGPPPQG-GNQSQGPPPP---PGKPEGRPPQGG 86

Query: 292 LPPGPPPPVP---------------GYGPPPGPP--PPQQG------PPPPPGPFPPRPP 328
                PPP P               G  PPPG P  PP QG      PPPPPG  P RPP
Sbjct: 87  NQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGK-PERPP 145

Query: 329 GPLGPPLTLAPPPHLPGPPPGAPPPAPHVN-PAFFPPPTNSGMPTSDSR----GPPPTDP 383
            P G   +  PPPH PG P G PP   + +  A  PP    G P  +       PPP  P
Sbjct: 146 -PQGGNQSQGPPPH-PGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKP 203

Query: 384 YGRPP 388
            G PP
Sbjct: 204 QGPPP 208



 Score = 93.2 bits (230), Expect = 6e-19
 Identities = 73/188 (38%), Positives = 80/188 (42%), Gaps = 36/188 (19%)

Query: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG----PGGPPPPFPAGQTPP------ 237
           PP G      PQGG  + + P   PG    P P G     G PPPP    + PP      
Sbjct: 73  PPPGKPEGRPPQGGN-QSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQS 131

Query: 238 -RPPLGPPGPPGPP--------GPPP-PGQVL-PPPLAGPPNRGDRPPPPVLFPGQPFGQ 286
            RPP  P  P  PP        GPPP PG+   PPP  G  +R  R P     PG+P G 
Sbjct: 132 HRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSP-----PGKPQGP 186

Query: 287 PPL-GPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPG 345
           P   G  P GPPPP    GPPP    PQQ   PP G    +P GP  PP    P    P 
Sbjct: 187 PQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAG----KPQGPPPPPQGGRP----PR 238

Query: 346 PPPGAPPP 353
           P  G  PP
Sbjct: 239 PAQGQQPP 246



 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 71/188 (37%), Positives = 82/188 (43%), Gaps = 53/188 (28%)

Query: 231 PAGQTPP--RPPLGPPGPPGPP-GPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQP 287
           P G+ P     P  PP PPG P GPPP G           N+   PPPP   PG+P G+P
Sbjct: 36  PEGRRPQGGNQPQRPPPPPGKPQGPPPQGG----------NQSQGPPPP---PGKPEGRP 82

Query: 288 PLGPLPPGPPPPVPGYGPPPGPPPPQ-----QGPPPPPGPFPPRPPGPLGPPLTLAPPPH 342
           P G      PPP PG    P  PPPQ     QG PPPPG  P RPP P G         H
Sbjct: 83  PQGGNQSQGPPPHPG---KPERPPPQGGNQSQGTPPPPGK-PERPP-PQG-----GNQSH 132

Query: 343 LPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREM 402
            P PPPG P           PPP       + S+GPPP         +     GPP +E 
Sbjct: 133 RPPPPPGKPER---------PPPQGG----NQSQGPPP---------HPGKPEGPPPQEG 170

Query: 403 DTARTPLS 410
           + +R+  S
Sbjct: 171 NKSRSARS 178



 Score = 80.1 bits (196), Expect = 5e-15
 Identities = 52/129 (40%), Positives = 57/129 (44%), Gaps = 11/129 (8%)

Query: 278 LFPGQPFGQPPLGPLPPGPPPPVPG--YGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPL 335
           L  G+P G+ P G   P  PPP PG   GPPP      QGPPPPPG    RP  P G   
Sbjct: 31  LISGKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRP--PQGGNQ 88

Query: 336 TLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMP-----TSDSRGPPPTDPYGRPPPY 390
           +  PPPH PG P   PP   + +    PPP     P         R PPP     RPPP 
Sbjct: 89  SQGPPPH-PGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQ 147

Query: 391 -DRGDYGPP 398
                 GPP
Sbjct: 148 GGNQSQGPP 156



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 51/156 (32%), Positives = 56/156 (35%), Gaps = 42/156 (26%)

Query: 172 RKTTQSGQMSGEGKAGPPGGSSRAAFPQGG---RGRGRFPGAVPG-----GDRFPGPAGP 223
           R   Q G  S   +  PP G      PQGG   +G    PG   G     G++      P
Sbjct: 122 RPPPQGGNQSH--RPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSP 179

Query: 224 GGPP--PPFPAGQTPPRPPLGPPG-PPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFP 280
            G P  PP   G  P  PP  PPG P G           PPP  G P +   PP      
Sbjct: 180 PGKPQGPPQQEGNKPQGPP--PPGKPQG-----------PPPAGGNPQQPQAPP------ 220

Query: 281 GQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGP 316
                       P GPPPP  G G PP P   QQ P
Sbjct: 221 ---------AGKPQGPPPPPQG-GRPPRPAQGQQPP 246



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 22/61 (36%), Positives = 25/61 (40%), Gaps = 2/61 (3%)

Query: 179 QMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGD-RFPGPAGPGGPPPPFPAGQTPP 237
           Q  G    GPP        P  G G  + P A P G  + P P   GG PP    GQ PP
Sbjct: 188 QQEGNKPQGPPPPGKPQGPPPAG-GNPQQPQAPPAGKPQGPPPPPQGGRPPRPAQGQQPP 246

Query: 238 R 238
           +
Sbjct: 247 Q 247


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 1691

 Score =  107 bits (266), Expect = 4e-23
 Identities = 104/287 (36%), Positives = 117/287 (40%), Gaps = 72/287 (25%)

Query: 178 GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP---PPFPAGQ 234
           GQ    G  GP G      F +G RG    P   PG    PG  GP GPP   PP P G+
Sbjct: 579 GQDGLPGLPGPKGEPGGITF-KGERG----PPGNPGLPGLPGNIGPMGPPGFGPPGPVGE 633

Query: 235 TPPRPPLGPPGPPGPPGPP-PPGQVLPPP----LAGPPNR-GDRPPPPVLFPGQPF--GQ 286
              +   G PG PG PGP   PGQ +  P    L G P R GD     V  PG P   GQ
Sbjct: 634 KGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGD-----VGLPGDPGLPGQ 688

Query: 287 PPLGPLP-------------PGPPPP--VPGYGPPPGPPPPQ-----QGPPPPPG----- 321
           P L  +P             PGPP P   PG   PPG P        +GPP PPG     
Sbjct: 689 PGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPK 748

Query: 322 -------PFPPRPPGPLGPPLTLAPP-----PHLPGPP-----PGAPPPAPHVNPAFFPP 364
                  P PP PPG  G    L P      P  PGPP      G P P   V P   P 
Sbjct: 749 GEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPG 808

Query: 365 PTN-SGMPTSDSRGPPP----TDPYGRPP----PYDRGDYGPPGREM 402
           P    G+P    +GPP       P G+P     P ++GD GPPG ++
Sbjct: 809 PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855



 Score =  100 bits (249), Expect = 3e-21
 Identities = 94/271 (34%), Positives = 109/271 (40%), Gaps = 63/271 (23%)

Query: 182  GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-------------PGGPPP 228
            G G  GPPG    +    G +G G  PG +PG    PGP G             PG P  
Sbjct: 1188 GFGNPGPPGLPGLS----GQKGDGGLPG-IPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS 1242

Query: 229  PFPAGQTPPRPPLGPPGPPGPPGPPP----PGQVLPPPLAG------------------- 265
            P PA + P   P GP GPPG PGP      PG   PP L G                   
Sbjct: 1243 PGPALEGPKGNP-GPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL 1301

Query: 266  PPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPP-PPVPGYGPPPGPP--PPQQGPPPPPG- 321
            P  +GD+ PP +   G P G+P L  +   P  P VPG+    GP   P   GP   PG 
Sbjct: 1302 PGLKGDQGPPGL--QGNP-GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL 1358

Query: 322  ---PFPPRPPGPLGPPLTL---APPPHLPGPPPGAPPPAPHVNPAFFPPPT-------NS 368
               P PP  PGP G  + +   A PP +PG P     P P   P   P PT        +
Sbjct: 1359 IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ-GPQGLPGPTGPPGDPGRN 1417

Query: 369  GMPTSDSRGPPPTDPYGRPPPYDRGDYGPPG 399
            G+P  D  G    DP     P  RG  GPPG
Sbjct: 1418 GLPGFDGAGGRKGDPGLPGQPGTRGLDGPPG 1448



 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 92/252 (36%), Positives = 102/252 (40%), Gaps = 53/252 (21%)

Query: 189 PGGSSRAAFPQGGRGRGRFPGAV--PGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGP 246
           PG     +  +G +G   FPG    PG   FPGP GP GP      GQ       GPPGP
Sbjct: 34  PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGP-----RGQKGDDGIPGPPGP 88

Query: 247 PGPPGPPP-PGQVLPPPLAGPPNRGDRPPPPVL-----------FPGQPFGQPPLGPLPP 294
            G  GPP  PG    P L G P     P P  +           FPG P G P L   PP
Sbjct: 89  KGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSP-GFPGLQG-PP 146

Query: 295 GPPPPVPGYGPPPGP------PPPQQGP--PPPPG----PFPPRPPGPLGPPLTLAPPPH 342
           G PP +PG    PG       P P+  P  P PPG    P P   PGP+GPP     PP 
Sbjct: 147 G-PPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPP----GPPG 201

Query: 343 LPGP--PPGAPPPAPHVNPAFFPPPTNSG-MPTSDSRGPPPTDPYGRPP----------- 388
           L GP  PPG P P  ++   F  P    G        GPP      + P           
Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261

Query: 389 -PYDRGDYGPPG 399
            P DRG  GPPG
Sbjct: 262 LPGDRGPPGPPG 273



 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 90/240 (37%), Positives = 101/240 (42%), Gaps = 38/240 (15%)

Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAV-----PGGDRFPGPAGPGG---PPPPFPAG 233
           G G  GPPG       P G  G    PG +     PG   FPGP G  G   P PP P G
Sbjct: 705 GIGLPGPPGPKGFPGIP-GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763

Query: 234 QTPPRPPLGPPGP---PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG 290
               +  LGP G    PGPPG  PPG+     L GP  +GD  P     P  P G P +G
Sbjct: 764 LPGFKGALGPKGDRGFPGPPG--PPGRTGLDGLPGP--KGDVGPNGQPGPMGPPGLPGIG 819

Query: 291 PLPPGPPPPVPGYGPPPGPP-----PPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPG 345
              P  PP +PG   P G P     P ++G P PPG   P PPG  G P      P  PG
Sbjct: 820 VQGPPGPPGIPG---PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP----GIPGAPG 872

Query: 346 P--PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMD 403
           P  PPG+P        + F P T   M      GPP   P G P     G  G PG + D
Sbjct: 873 PIGPPGSPGLPGKAGASGF-PGTKGEMGMMGPPGPP--GPLGIP-----GRSGVPGLKGD 924



 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 93/271 (34%), Positives = 105/271 (38%), Gaps = 56/271 (20%)

Query: 174  TTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG----PGGPPPP 229
            T + G     G  GPPG         G +G    PG +PG     GP G    PG P  P
Sbjct: 937  TGEKGSKGEPGLPGPPGPMDPNLL--GSKGEKGEPG-LPGIPGVSGPKGYQGLPGDPGQP 993

Query: 230  FPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGP--------PNRGDRPPPPVLFPG 281
              +GQ     P GP G PG PG   PG + PP L G         P   + PP P   PG
Sbjct: 994  GLSGQPGLPGPPGPKGNPGLPG--QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPG 1051

Query: 282  QPFGQPPLG----------------PLPPGP--PPPVPGY----------GPP--PGPP- 310
            QP G P L                 P  PGP   P +PGY          G P  PG P 
Sbjct: 1052 QP-GSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPG 1110

Query: 311  -PPQQGPPPPPG-PFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNS 368
             P  +G P  PG P  P PPGP G    ++ PP  PG P    P     +P    PP   
Sbjct: 1111 TPGAKGQPGLPGFPGTPGPPGPKG----ISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK 1166

Query: 369  GMPTSDSRGPPPTDPYGRPPPYDRGDYGPPG 399
            G P  D   P P    G P     G+ GPPG
Sbjct: 1167 GKPGQDGI-PGPAGQKGEPGQPGFGNPGPPG 1196



 Score = 90.1 bits (222), Expect = 5e-18
 Identities = 103/295 (34%), Positives = 106/295 (35%), Gaps = 78/295 (26%)

Query: 176  QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAV--PG-----GDR-FPGPAGPGGPP 227
            Q G     G  GPPG       P+G  G    PG +  PG     GD  FPGP G  GPP
Sbjct: 992  QPGLSGQPGLPGPPG-------PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044

Query: 228  PPFPAGQTPPRP------------------------PLGPPGPPGPPGPPP-PGQVLPPP 262
             P      P  P                        P G PG PG PG P   G V  P 
Sbjct: 1045 GPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPG 1104

Query: 263  LAGPPNRGDRPPPPVL--FPGQP-------FGQPPLGPLPPGPPPPVPGYGPP--PGPP- 310
            L G P        P L  FPG P          PP  P  PG P PV G G P  PGPP 
Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164

Query: 311  ----PPQQGPPPPPGP--FPPRP----PGPLGPPLTLAPPPH--LPGPPPGAPPPAPHVN 358
                P Q G P P G    P +P    PGP G P          LPG P     P P   
Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE 1224

Query: 359  PAF--FP----PPTNSGMPTSDSRGPP----PTDPYGRPPPYD----RGDYGPPG 399
            P F  FP    PP   G P     GP     P  P GRP P       G  GPPG
Sbjct: 1225 PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPG 1279



 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 88/246 (35%), Positives = 96/246 (39%), Gaps = 50/246 (20%)

Query: 176  QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDR--FPGPAGPGGPPP----P 229
            Q G     G  GPPG    +  P G  G    PG V GG     PGP G  G P     P
Sbjct: 1117 QPGLPGFPGTPGPPGPKGISG-PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIP 1175

Query: 230  FPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRP--PPPVLFPGQPFGQP 287
             PAGQ       G PG PG   P PPG    P L+G    G  P  P     PG P G+P
Sbjct: 1176 GPAGQK------GEPGQPGFGNPGPPGL---PGLSGQKGDGGLPGIPGNPGLPG-PKGEP 1225

Query: 288  PLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGP-FPPRPPGPLGPPLTLAPPPHLPGP 346
                 P    PP    GPP  P P  +GP   PGP  PP  PGP G          LPGP
Sbjct: 1226 GFHGFPGVQGPP----GPPGSPGPALEGPKGNPGPQGPPGRPGPTG-------FQGLPGP 1274

Query: 347  --PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDT 404
              PPG P      N        N G P     G P         P  +GD GPPG + + 
Sbjct: 1275 EGPPGLPG-----NGGIKGEKGNPGQP-----GLPGL-------PGLKGDQGPPGLQGNP 1317

Query: 405  ARTPLS 410
             R  L+
Sbjct: 1318 GRPGLN 1323



 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 87/255 (34%), Positives = 99/255 (38%), Gaps = 43/255 (16%)

Query: 178  GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPG-----AVPGGDRFPGPAG-------PGG 225
            G+M   G  GPPG       P G  GR   PG      + G    PGP G       PG 
Sbjct: 896  GEMGMMGPPGPPG-------PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL 948

Query: 226  PPPPFPA-----GQTPPRPPLGPPGPPGPPGPPP----PGQVLPPPLAGPPNRGDRPPPP 276
            P PP P      G    +   G PG PG  GP      PG    P L+G P     PP P
Sbjct: 949  PGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL-PGPPGP 1007

Query: 277  VLFPGQPFGQPPLGPLPPGPPPPVPGYGPP-----PGPPPPQQGPPPPPGPFPPRPPGPL 331
               PG P GQP L   PPG    +   G P      GPP P   P  P  P  P   G  
Sbjct: 1008 KGNPGLP-GQPGLIG-PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 332  GPP-LTLAPPPHLPGP--PPGAP--PPAPHVNPAFFPP--PTNSGMPTSDSRGPPPTDPY 384
            G P ++    P LPGP   PG P  P  P +  +   P  P   G P +  +   P  P 
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 1125

Query: 385  GRPPPYDRGDYGPPG 399
               PP  +G  GPPG
Sbjct: 1126 TPGPPGPKGISGPPG 1140



 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 97/320 (30%), Positives = 110/320 (34%), Gaps = 111/320 (34%)

Query: 184 GKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-PGGPPPPFPAGQTPPRP--- 239
           G  GPPG       P G  G    PG++      PGP G PG P PP   G   P     
Sbjct: 141 GLQGPPG-------PPGIPGMKGEPGSIIMSS-LPGPKGNPGYPGPPGIQGLPGPTGIPG 192

Query: 240 PLGPPGPPG---PPGPP---------------PPGQVLPPPLAGPPN-----RGDRPPPP 276
           P+GPPGPPG   PPGPP               P G+     L GPP         + P  
Sbjct: 193 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 277 VLF----PGQPFGQPPLGPL----PPGPP---------------------------PPVP 301
           V F     G P  + P GP     PPGPP                           P +P
Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 302 GYGPPPGPP-----------PPQQGPPPPPGPFPPRP--------PGPLGPP-------- 334
           G    PG P               GPP PPG   PRP         G +G P        
Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372

Query: 335 ---LTLAPPPHLPGPPPGA--PPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP-- 387
                +  PP LPGPP  A   PP P   P       + G P     GPP  D  G+P  
Sbjct: 373 RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLD--GQPGA 430

Query: 388 -----PPYDRGDYGPPGREM 402
                PP   G + PP  E+
Sbjct: 431 PGLPGPPGPAGPHIPPSDEI 450



 Score = 72.8 bits (177), Expect = 8e-13
 Identities = 92/287 (32%), Positives = 103/287 (35%), Gaps = 72/287 (25%)

Query: 176 QSGQMSGEGKAGPPG------GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGG-PPP 228
           + GQ    G  GPPG      G+      +G  G    PG   G   FPG  GP G P P
Sbjct: 329 EKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE-KGERGFPGIQGPPGLPGP 387

Query: 229 PFPAGQTPPRPP--------LGPPGPPGPPGPPPP---GQVLPPPLAGPPNRGDRPPPPV 277
           P  A   PP PP         G  GPPG   P PP   GQ   P L GPP     P  P 
Sbjct: 388 PGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPG----PAGPH 443

Query: 278 LFPGQPFGQPPLGPLPPGPP--PPVPGYGPPPGPPPPQ------------QGPPPPPG-P 322
           + P     +P     PPGPP  P   G     G    +             GPP  PG P
Sbjct: 444 IPPSDEICEPG----PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499

Query: 323 FPPRPPGPLGPP--------LTLAPPPHLPGPP--PGAPP-PAPHVNPA---FFP----- 363
             P PPG LG P             P  LPG P  PGAP  P     P     FP     
Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD 559

Query: 364 --------PPTNSGMPTSDSRG--PPPTDPYGRPPPYD-RGDYGPPG 399
                    P   G+P +  +   P    P G P     +G+ GPPG
Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 61/161 (37%), Positives = 67/161 (41%), Gaps = 27/161 (16%)

Query: 183  EGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLG 242
            +G  GPPG       P G  G    PG +PG   FPG  GP G P    AG       +G
Sbjct: 1305 KGDQGPPGLQGNPGRP-GLNGMKGDPG-LPGVPGFPGMKGPSGVPGS--AGPEGEPGLIG 1360

Query: 243  PPGPPGPPGPPPPGQVL-----PPPLAGPPNRGDRPPP--PVLFPGQ--PFGQPPLGPLP 293
            PPGPPG PGP     ++     PP + G P     P P  P   PG   P G P    LP
Sbjct: 1361 PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP 1420

Query: 294  -----------PGPP--PPVPGYGPPPGPPPPQQGPPPPPG 321
                       PG P  P   G   PPGP    QGPP PPG
Sbjct: 1421 GFDGAGGRKGDPGLPGQPGTRGLDGPPGPDG-LQGPPGPPG 1460



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 36/108 (33%), Positives = 42/108 (38%), Gaps = 19/108 (17%)

Query: 176  QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQT 235
            + G +   G  G PG S ++   +G  G    PG  PG    PGP GP G P P      
Sbjct: 1355 EPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQ-PGLKGLPGPQGPQGLPGPTGPPGD 1413

Query: 236  PPRPPL----------------GPPGPPGPPGPPPPGQVLPPPLAGPP 267
            P R  L                G PG  G  GPP P  +  PP  GPP
Sbjct: 1414 PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPP--GPP 1459



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 37/91 (40%), Positives = 40/91 (43%), Gaps = 19/91 (20%)

Query: 183  EGKAGPPG-----GSSRAAFPQGGRGRGRFPGAV-----PGGDRFPGPAGPGGPP--PPF 230
            +G AGPPG     G      PQG +G    PG       PG +  PG  G GG    P  
Sbjct: 1378 KGDAGPPGIPGQPGLKGLPGPQGPQG---LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1434

Query: 231  PAGQTPPRPPLGPPGPPG---PPGPPPPGQV 258
            P GQ   R   GPPGP G   PPGPP    V
Sbjct: 1435 P-GQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1464



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 28/73 (38%), Positives = 29/73 (39%), Gaps = 2/73 (2%)

Query: 178  GQMSGEGKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQT 235
            GQ   +G  GP G  G      P G  GR   PG    G R   P  PG P      G  
Sbjct: 1388 GQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPP 1447

Query: 236  PPRPPLGPPGPPG 248
             P    GPPGPPG
Sbjct: 1448 GPDGLQGPPGPPG 1460


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
           sapiens]
          Length = 1685

 Score =  107 bits (266), Expect = 4e-23
 Identities = 104/287 (36%), Positives = 117/287 (40%), Gaps = 72/287 (25%)

Query: 178 GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP---PPFPAGQ 234
           GQ    G  GP G      F +G RG    P   PG    PG  GP GPP   PP P G+
Sbjct: 579 GQDGLPGLPGPKGEPGGITF-KGERG----PPGNPGLPGLPGNIGPMGPPGFGPPGPVGE 633

Query: 235 TPPRPPLGPPGPPGPPGPP-PPGQVLPPP----LAGPPNR-GDRPPPPVLFPGQPF--GQ 286
              +   G PG PG PGP   PGQ +  P    L G P R GD     V  PG P   GQ
Sbjct: 634 KGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGD-----VGLPGDPGLPGQ 688

Query: 287 PPLGPLP-------------PGPPPP--VPGYGPPPGPPPPQ-----QGPPPPPG----- 321
           P L  +P             PGPP P   PG   PPG P        +GPP PPG     
Sbjct: 689 PGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPK 748

Query: 322 -------PFPPRPPGPLGPPLTLAPP-----PHLPGPP-----PGAPPPAPHVNPAFFPP 364
                  P PP PPG  G    L P      P  PGPP      G P P   V P   P 
Sbjct: 749 GEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPG 808

Query: 365 PTN-SGMPTSDSRGPPP----TDPYGRPP----PYDRGDYGPPGREM 402
           P    G+P    +GPP       P G+P     P ++GD GPPG ++
Sbjct: 809 PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855



 Score =  102 bits (253), Expect = 1e-21
 Identities = 94/267 (35%), Positives = 109/267 (40%), Gaps = 61/267 (22%)

Query: 182  GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG----------------PGG 225
            G G  GPPG    +    G +G G  PG +PG    PGP G                PG 
Sbjct: 1188 GFGNPGPPGLPGLS----GQKGDGGLPG-IPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS 1242

Query: 226  PPPPF--PAGQTPPRPPLGPPGPPGPPGPP-------------PPGQVLPPPLAGPPN-R 269
            P P    P G   P+ P G PG PGP GPP              PGQ   P L G P  +
Sbjct: 1243 PGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQ---PGLPGLPGLK 1299

Query: 270  GDRPPPPVLFPGQPFGQPPLGPLPPGPP-PPVPGYGPPPGPP--PPQQGPPPPPG----P 322
            GD+ PP +   G P G+P L  +   P  P VPG+    GP   P   GP   PG    P
Sbjct: 1300 GDQGPPGL--QGNP-GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPP 1356

Query: 323  FPPRPPGPLGPPLTL---APPPHLPGPPPGAPPPAPHVNPAFFPPPT-------NSGMPT 372
             PP  PGP G  + +   A PP +PG P     P P   P   P PT        +G+P 
Sbjct: 1357 GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ-GPQGLPGPTGPPGDPGRNGLPG 1415

Query: 373  SDSRGPPPTDPYGRPPPYDRGDYGPPG 399
             D  G    DP     P  RG  GPPG
Sbjct: 1416 FDGAGGRKGDPGLPGQPGTRGLDGPPG 1442



 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 92/252 (36%), Positives = 102/252 (40%), Gaps = 53/252 (21%)

Query: 189 PGGSSRAAFPQGGRGRGRFPGAV--PGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGP 246
           PG     +  +G +G   FPG    PG   FPGP GP GP      GQ       GPPGP
Sbjct: 34  PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGP-----RGQKGDDGIPGPPGP 88

Query: 247 PGPPGPPP-PGQVLPPPLAGPPNRGDRPPPPVL-----------FPGQPFGQPPLGPLPP 294
            G  GPP  PG    P L G P     P P  +           FPG P G P L   PP
Sbjct: 89  KGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSP-GFPGLQG-PP 146

Query: 295 GPPPPVPGYGPPPGP------PPPQQGP--PPPPG----PFPPRPPGPLGPPLTLAPPPH 342
           G PP +PG    PG       P P+  P  P PPG    P P   PGP+GPP     PP 
Sbjct: 147 G-PPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPP----GPPG 201

Query: 343 LPGP--PPGAPPPAPHVNPAFFPPPTNSG-MPTSDSRGPPPTDPYGRPP----------- 388
           L GP  PPG P P  ++   F  P    G        GPP      + P           
Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261

Query: 389 -PYDRGDYGPPG 399
            P DRG  GPPG
Sbjct: 262 LPGDRGPPGPPG 273



 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 90/240 (37%), Positives = 101/240 (42%), Gaps = 38/240 (15%)

Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAV-----PGGDRFPGPAGPGG---PPPPFPAG 233
           G G  GPPG       P G  G    PG +     PG   FPGP G  G   P PP P G
Sbjct: 705 GIGLPGPPGPKGFPGIP-GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763

Query: 234 QTPPRPPLGPPGP---PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG 290
               +  LGP G    PGPPG  PPG+     L GP  +GD  P     P  P G P +G
Sbjct: 764 LPGFKGALGPKGDRGFPGPPG--PPGRTGLDGLPGP--KGDVGPNGQPGPMGPPGLPGIG 819

Query: 291 PLPPGPPPPVPGYGPPPGPP-----PPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPG 345
              P  PP +PG   P G P     P ++G P PPG   P PPG  G P      P  PG
Sbjct: 820 VQGPPGPPGIPG---PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP----GIPGAPG 872

Query: 346 P--PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMD 403
           P  PPG+P        + F P T   M      GPP   P G P     G  G PG + D
Sbjct: 873 PIGPPGSPGLPGKAGASGF-PGTKGEMGMMGPPGPP--GPLGIP-----GRSGVPGLKGD 924



 Score = 91.7 bits (226), Expect = 2e-18
 Identities = 108/335 (32%), Positives = 117/335 (34%), Gaps = 109/335 (32%)

Query: 176  QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAV--PG-----GDR-FPGPAGPGGPP 227
            Q G     G  GPPG       P+G  G    PG +  PG     GD  FPGP G  GPP
Sbjct: 992  QPGLSGQPGLPGPPG-------PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044

Query: 228  PPFPAGQTPPRP------------------------PLGPPGPPGPPGPPP-PGQVLPPP 262
             P      P  P                        P G PG PG PG P   G V  P 
Sbjct: 1045 GPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPG 1104

Query: 263  LAGPPNRGDRPPPPVL--FPGQP-------FGQPPLGPLPPGPPPPVPGYGPP--PGPP- 310
            L G P        P L  FPG P          PP  P  PG P PV G G P  PGPP 
Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164

Query: 311  ----PPQQGPPPPPG------------PFPPRPPGPLGPPLTLAPP-----PHLPGP--- 346
                P Q G P P G            P PP  PG  G       P     P LPGP   
Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE 1224

Query: 347  --------------PPGAPPPA---PHVNPAFFPPPTNSGMPTSDSRGPP---------- 379
                          PPG+P PA   P  NP    PP   G+P  +  GPP          
Sbjct: 1225 PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPE--GPPGLPGNGGIKG 1282

Query: 380  ----PTDPYGRPPPYDRGDYGPPGREMDTARTPLS 410
                P  P     P  +GD GPPG + +  R  L+
Sbjct: 1283 EKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLN 1317



 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 93/271 (34%), Positives = 105/271 (38%), Gaps = 56/271 (20%)

Query: 174  TTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG----PGGPPPP 229
            T + G     G  GPPG         G +G    PG +PG     GP G    PG P  P
Sbjct: 937  TGEKGSKGEPGLPGPPGPMDPNLL--GSKGEKGEPG-LPGIPGVSGPKGYQGLPGDPGQP 993

Query: 230  FPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGP--------PNRGDRPPPPVLFPG 281
              +GQ     P GP G PG PG   PG + PP L G         P   + PP P   PG
Sbjct: 994  GLSGQPGLPGPPGPKGNPGLPG--QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPG 1051

Query: 282  QPFGQPPLG----------------PLPPGP--PPPVPGY----------GPP--PGPP- 310
            QP G P L                 P  PGP   P +PGY          G P  PG P 
Sbjct: 1052 QP-GSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPG 1110

Query: 311  -PPQQGPPPPPG-PFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNS 368
             P  +G P  PG P  P PPGP G    ++ PP  PG P    P     +P    PP   
Sbjct: 1111 TPGAKGQPGLPGFPGTPGPPGPKG----ISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK 1166

Query: 369  GMPTSDSRGPPPTDPYGRPPPYDRGDYGPPG 399
            G P  D   P P    G P     G+ GPPG
Sbjct: 1167 GKPGQDGI-PGPAGQKGEPGQPGFGNPGPPG 1196



 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 87/255 (34%), Positives = 99/255 (38%), Gaps = 43/255 (16%)

Query: 178  GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPG-----AVPGGDRFPGPAG-------PGG 225
            G+M   G  GPPG       P G  GR   PG      + G    PGP G       PG 
Sbjct: 896  GEMGMMGPPGPPG-------PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL 948

Query: 226  PPPPFPA-----GQTPPRPPLGPPGPPGPPGPPP----PGQVLPPPLAGPPNRGDRPPPP 276
            P PP P      G    +   G PG PG  GP      PG    P L+G P     PP P
Sbjct: 949  PGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL-PGPPGP 1007

Query: 277  VLFPGQPFGQPPLGPLPPGPPPPVPGYGPP-----PGPPPPQQGPPPPPGPFPPRPPGPL 331
               PG P GQP L   PPG    +   G P      GPP P   P  P  P  P   G  
Sbjct: 1008 KGNPGLP-GQPGLIG-PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 332  GPP-LTLAPPPHLPGP--PPGAP--PPAPHVNPAFFPP--PTNSGMPTSDSRGPPPTDPY 384
            G P ++    P LPGP   PG P  P  P +  +   P  P   G P +  +   P  P 
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 1125

Query: 385  GRPPPYDRGDYGPPG 399
               PP  +G  GPPG
Sbjct: 1126 TPGPPGPKGISGPPG 1140



 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 97/320 (30%), Positives = 110/320 (34%), Gaps = 111/320 (34%)

Query: 184 GKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-PGGPPPPFPAGQTPPRP--- 239
           G  GPPG       P G  G    PG++      PGP G PG P PP   G   P     
Sbjct: 141 GLQGPPG-------PPGIPGMKGEPGSIIMSS-LPGPKGNPGYPGPPGIQGLPGPTGIPG 192

Query: 240 PLGPPGPPG---PPGPP---------------PPGQVLPPPLAGPPN-----RGDRPPPP 276
           P+GPPGPPG   PPGPP               P G+     L GPP         + P  
Sbjct: 193 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 277 VLF----PGQPFGQPPLGPL----PPGPP---------------------------PPVP 301
           V F     G P  + P GP     PPGPP                           P +P
Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 302 GYGPPPGPP-----------PPQQGPPPPPGPFPPRP--------PGPLGPP-------- 334
           G    PG P               GPP PPG   PRP         G +G P        
Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372

Query: 335 ---LTLAPPPHLPGPPPGA--PPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP-- 387
                +  PP LPGPP  A   PP P   P       + G P     GPP  D  G+P  
Sbjct: 373 RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLD--GQPGA 430

Query: 388 -----PPYDRGDYGPPGREM 402
                PP   G + PP  E+
Sbjct: 431 PGLPGPPGPAGPHIPPSDEI 450



 Score = 72.8 bits (177), Expect = 8e-13
 Identities = 92/287 (32%), Positives = 103/287 (35%), Gaps = 72/287 (25%)

Query: 176 QSGQMSGEGKAGPPG------GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGG-PPP 228
           + GQ    G  GPPG      G+      +G  G    PG   G   FPG  GP G P P
Sbjct: 329 EKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE-KGERGFPGIQGPPGLPGP 387

Query: 229 PFPAGQTPPRPP--------LGPPGPPGPPGPPPP---GQVLPPPLAGPPNRGDRPPPPV 277
           P  A   PP PP         G  GPPG   P PP   GQ   P L GPP     P  P 
Sbjct: 388 PGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPG----PAGPH 443

Query: 278 LFPGQPFGQPPLGPLPPGPP--PPVPGYGPPPGPPPPQ------------QGPPPPPG-P 322
           + P     +P     PPGPP  P   G     G    +             GPP  PG P
Sbjct: 444 IPPSDEICEPG----PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499

Query: 323 FPPRPPGPLGPP--------LTLAPPPHLPGPP--PGAPP-PAPHVNPA---FFP----- 363
             P PPG LG P             P  LPG P  PGAP  P     P     FP     
Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD 559

Query: 364 --------PPTNSGMPTSDSRG--PPPTDPYGRPPPYD-RGDYGPPG 399
                    P   G+P +  +   P    P G P     +G+ GPPG
Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 61/161 (37%), Positives = 67/161 (41%), Gaps = 27/161 (16%)

Query: 183  EGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLG 242
            +G  GPPG       P G  G    PG +PG   FPG  GP G P    AG       +G
Sbjct: 1299 KGDQGPPGLQGNPGRP-GLNGMKGDPG-LPGVPGFPGMKGPSGVPGS--AGPEGEPGLIG 1354

Query: 243  PPGPPGPPGPPPPGQVL-----PPPLAGPPNRGDRPPP--PVLFPGQ--PFGQPPLGPLP 293
            PPGPPG PGP     ++     PP + G P     P P  P   PG   P G P    LP
Sbjct: 1355 PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP 1414

Query: 294  -----------PGPP--PPVPGYGPPPGPPPPQQGPPPPPG 321
                       PG P  P   G   PPGP    QGPP PPG
Sbjct: 1415 GFDGAGGRKGDPGLPGQPGTRGLDGPPGPDG-LQGPPGPPG 1454



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 36/108 (33%), Positives = 42/108 (38%), Gaps = 19/108 (17%)

Query: 176  QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQT 235
            + G +   G  G PG S ++   +G  G    PG  PG    PGP GP G P P      
Sbjct: 1349 EPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQ-PGLKGLPGPQGPQGLPGPTGPPGD 1407

Query: 236  PPRPPL----------------GPPGPPGPPGPPPPGQVLPPPLAGPP 267
            P R  L                G PG  G  GPP P  +  PP  GPP
Sbjct: 1408 PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPP--GPP 1453



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 37/91 (40%), Positives = 40/91 (43%), Gaps = 19/91 (20%)

Query: 183  EGKAGPPG-----GSSRAAFPQGGRGRGRFPGAV-----PGGDRFPGPAGPGGPP--PPF 230
            +G AGPPG     G      PQG +G    PG       PG +  PG  G GG    P  
Sbjct: 1372 KGDAGPPGIPGQPGLKGLPGPQGPQG---LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1428

Query: 231  PAGQTPPRPPLGPPGPPG---PPGPPPPGQV 258
            P GQ   R   GPPGP G   PPGPP    V
Sbjct: 1429 P-GQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1458



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 28/73 (38%), Positives = 29/73 (39%), Gaps = 2/73 (2%)

Query: 178  GQMSGEGKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQT 235
            GQ   +G  GP G  G      P G  GR   PG    G R   P  PG P      G  
Sbjct: 1382 GQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPP 1441

Query: 236  PPRPPLGPPGPPG 248
             P    GPPGPPG
Sbjct: 1442 GPDGLQGPPGPPG 1454


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
           sapiens]
          Length = 1688

 Score =  107 bits (266), Expect = 4e-23
 Identities = 104/287 (36%), Positives = 117/287 (40%), Gaps = 72/287 (25%)

Query: 178 GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP---PPFPAGQ 234
           GQ    G  GP G      F +G RG    P   PG    PG  GP GPP   PP P G+
Sbjct: 579 GQDGLPGLPGPKGEPGGITF-KGERG----PPGNPGLPGLPGNIGPMGPPGFGPPGPVGE 633

Query: 235 TPPRPPLGPPGPPGPPGPP-PPGQVLPPP----LAGPPNR-GDRPPPPVLFPGQPF--GQ 286
              +   G PG PG PGP   PGQ +  P    L G P R GD     V  PG P   GQ
Sbjct: 634 KGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGD-----VGLPGDPGLPGQ 688

Query: 287 PPLGPLP-------------PGPPPP--VPGYGPPPGPPPPQ-----QGPPPPPG----- 321
           P L  +P             PGPP P   PG   PPG P        +GPP PPG     
Sbjct: 689 PGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPK 748

Query: 322 -------PFPPRPPGPLGPPLTLAPP-----PHLPGPP-----PGAPPPAPHVNPAFFPP 364
                  P PP PPG  G    L P      P  PGPP      G P P   V P   P 
Sbjct: 749 GEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPG 808

Query: 365 PTN-SGMPTSDSRGPPP----TDPYGRPP----PYDRGDYGPPGREM 402
           P    G+P    +GPP       P G+P     P ++GD GPPG ++
Sbjct: 809 PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855



 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 92/252 (36%), Positives = 102/252 (40%), Gaps = 53/252 (21%)

Query: 189 PGGSSRAAFPQGGRGRGRFPGAV--PGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGP 246
           PG     +  +G +G   FPG    PG   FPGP GP GP      GQ       GPPGP
Sbjct: 34  PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGP-----RGQKGDDGIPGPPGP 88

Query: 247 PGPPGPPP-PGQVLPPPLAGPPNRGDRPPPPVL-----------FPGQPFGQPPLGPLPP 294
            G  GPP  PG    P L G P     P P  +           FPG P G P L   PP
Sbjct: 89  KGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSP-GFPGLQG-PP 146

Query: 295 GPPPPVPGYGPPPGP------PPPQQGP--PPPPG----PFPPRPPGPLGPPLTLAPPPH 342
           G PP +PG    PG       P P+  P  P PPG    P P   PGP+GPP     PP 
Sbjct: 147 G-PPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPP----GPPG 201

Query: 343 LPGP--PPGAPPPAPHVNPAFFPPPTNSG-MPTSDSRGPPPTDPYGRPP----------- 388
           L GP  PPG P P  ++   F  P    G        GPP      + P           
Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261

Query: 389 -PYDRGDYGPPG 399
            P DRG  GPPG
Sbjct: 262 LPGDRGPPGPPG 273



 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 90/240 (37%), Positives = 101/240 (42%), Gaps = 38/240 (15%)

Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAV-----PGGDRFPGPAGPGG---PPPPFPAG 233
           G G  GPPG       P G  G    PG +     PG   FPGP G  G   P PP P G
Sbjct: 705 GIGLPGPPGPKGFPGIP-GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763

Query: 234 QTPPRPPLGPPGP---PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG 290
               +  LGP G    PGPPG  PPG+     L GP  +GD  P     P  P G P +G
Sbjct: 764 LPGFKGALGPKGDRGFPGPPG--PPGRTGLDGLPGP--KGDVGPNGQPGPMGPPGLPGIG 819

Query: 291 PLPPGPPPPVPGYGPPPGPP-----PPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPG 345
              P  PP +PG   P G P     P ++G P PPG   P PPG  G P      P  PG
Sbjct: 820 VQGPPGPPGIPG---PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP----GIPGAPG 872

Query: 346 P--PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMD 403
           P  PPG+P        + F P T   M      GPP   P G P     G  G PG + D
Sbjct: 873 PIGPPGSPGLPGKAGASGF-PGTKGEMGMMGPPGPP--GPLGIP-----GRSGVPGLKGD 924



 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 94/267 (35%), Positives = 108/267 (40%), Gaps = 58/267 (21%)

Query: 182  GEGKAGPPGGSSRAAFPQGGRGRGRFPG-----------AVPGGDRFPGPAGPGGPP-PP 229
            G G  GPPG    +    G +G G  PG             PG   FPG  GP GPP  P
Sbjct: 1188 GFGNPGPPGLPGLS----GQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSP 1243

Query: 230  FPAGQTPPRPPLGPPGPPGPPG-PPPPGQVLPPPLAG-------------------PPNR 269
             PA + P   P GP GPPG PG    PG   PP L G                   P  +
Sbjct: 1244 GPALEGPKGNP-GPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK 1302

Query: 270  GDRPPPPVLFPGQPFGQPPLGPLPPGPP-PPVPGYGPPPGPP--PPQQGPPPPPG----P 322
            GD+ PP +   G P G+P L  +   P  P VPG+    GP   P   GP   PG    P
Sbjct: 1303 GDQGPPGL--QGNP-GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPP 1359

Query: 323  FPPRPPGPLGPPLTL---APPPHLPGPPPGAPPPAPHVNPAFFPPPT-------NSGMPT 372
             PP  PGP G  + +   A PP +PG P     P P   P   P PT        +G+P 
Sbjct: 1360 GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ-GPQGLPGPTGPPGDPGRNGLPG 1418

Query: 373  SDSRGPPPTDPYGRPPPYDRGDYGPPG 399
             D  G    DP     P  RG  GPPG
Sbjct: 1419 FDGAGGRKGDPGLPGQPGTRGLDGPPG 1445



 Score = 95.9 bits (237), Expect = 9e-20
 Identities = 97/272 (35%), Positives = 106/272 (38%), Gaps = 62/272 (22%)

Query: 180  MSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAV--PGGDRFPGPAGPGGPP--PPFPAGQT 235
            +S  G  G PG       P G  G     G+V  PG    PG  G  G P  P FP    
Sbjct: 1070 ISSIGLPGLPGPKGEPGLP-GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG 1128

Query: 236  PPRPP--LGPPGPPGPPGPPPP-------GQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQ 286
            PP P    GPPG PG PG P P       GQ  PP   G P + D  P P    G+P GQ
Sbjct: 1129 PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ-DGIPGPAGQKGEP-GQ 1186

Query: 287  PPLG-PLPPGPP-----------PPVPGYGPPPGPP--------PPQQGPPPPPGPFPPR 326
            P  G P PPG P           P +PG    PGP         P  QGPP PPG   P 
Sbjct: 1187 PGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPA 1246

Query: 327  PPGPLGPPLTLAPPPH-----LPGP--PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPP 379
              GP G P    PP       LPGP  PPG P      N        N G P        
Sbjct: 1247 LEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPG-----NGGIKGEKGNPGQP-------- 1293

Query: 380  PTDPYGRPP-PYDRGDYGPPGREMDTARTPLS 410
                 G P  P  +GD GPPG + +  R  L+
Sbjct: 1294 -----GLPGLPGLKGDQGPPGLQGNPGRPGLN 1320



 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 93/271 (34%), Positives = 105/271 (38%), Gaps = 56/271 (20%)

Query: 174  TTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG----PGGPPPP 229
            T + G     G  GPPG         G +G    PG +PG     GP G    PG P  P
Sbjct: 937  TGEKGSKGEPGLPGPPGPMDPNLL--GSKGEKGEPG-LPGIPGVSGPKGYQGLPGDPGQP 993

Query: 230  FPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGP--------PNRGDRPPPPVLFPG 281
              +GQ     P GP G PG PG   PG + PP L G         P   + PP P   PG
Sbjct: 994  GLSGQPGLPGPPGPKGNPGLPG--QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPG 1051

Query: 282  QPFGQPPLG----------------PLPPGP--PPPVPGY----------GPP--PGPP- 310
            QP G P L                 P  PGP   P +PGY          G P  PG P 
Sbjct: 1052 QP-GSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPG 1110

Query: 311  -PPQQGPPPPPG-PFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNS 368
             P  +G P  PG P  P PPGP G    ++ PP  PG P    P     +P    PP   
Sbjct: 1111 TPGAKGQPGLPGFPGTPGPPGPKG----ISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK 1166

Query: 369  GMPTSDSRGPPPTDPYGRPPPYDRGDYGPPG 399
            G P  D   P P    G P     G+ GPPG
Sbjct: 1167 GKPGQDGI-PGPAGQKGEPGQPGFGNPGPPG 1196



 Score = 90.1 bits (222), Expect = 5e-18
 Identities = 99/283 (34%), Positives = 102/283 (36%), Gaps = 70/283 (24%)

Query: 176  QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAV--PG-----GDR-FPGPAGPGGPP 227
            Q G     G  GPPG       P+G  G    PG +  PG     GD  FPGP G  GPP
Sbjct: 992  QPGLSGQPGLPGPPG-------PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044

Query: 228  PPFPAGQTPPRP------------------------PLGPPGPPGPPGPPP-PGQVLPPP 262
             P      P  P                        P G PG PG PG P   G V  P 
Sbjct: 1045 GPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPG 1104

Query: 263  LAGPPNRGDRPPPPVL--FPGQP-------FGQPPLGPLPPGPPPPVPGYGPP--PGPP- 310
            L G P        P L  FPG P          PP  P  PG P PV G G P  PGPP 
Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164

Query: 311  ----PPQQGPPPPPGP--FPPRP----PGPLGPPLTLAPPPH--LPGPPPGAPPPAPHVN 358
                P Q G P P G    P +P    PGP G P          LPG P     P P   
Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE 1224

Query: 359  PAFFPPPTNSGMP-TSDSRGPPPTDPYGRPPPYDRGDYGPPGR 400
            P F   P   G P    S GP    P G P     G  GPPGR
Sbjct: 1225 PGFHGFPGVQGPPGPPGSPGPALEGPKGNP-----GPQGPPGR 1262



 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 101/279 (36%), Positives = 108/279 (38%), Gaps = 68/279 (24%)

Query: 176  QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDR--FPGPAGPGGPPP----P 229
            Q G     G  GPPG    +  P G  G    PG V GG     PGP G  G P     P
Sbjct: 1117 QPGLPGFPGTPGPPGPKGISG-PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIP 1175

Query: 230  FPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRP--PPPVLFPGQPFGQP 287
             PAGQ       G PG PG   P PPG    P L+G    G  P  P     PG P G+P
Sbjct: 1176 GPAGQK------GEPGQPGFGNPGPPGL---PGLSGQKGDGGLPGIPGNPGLPG-PKGEP 1225

Query: 288  -----PLGPLPPGPP-PPVPGYGPPPGPPPPQQGPPPPPG----PFPPRPPG-------- 329
                 P    PPGPP  P P    P G P P QGPP  PG    P P  PPG        
Sbjct: 1226 GFHGFPGVQGPPGPPGSPGPALEGPKGNPGP-QGPPGRPGFQGLPGPEGPPGLPGNGGIK 1284

Query: 330  -----PLGPPLTLAP-------PPHLPGPP--PG-----APPPAPHVNPAFFPPPTNSGM 370
                 P  P L   P       PP L G P  PG       P  P V P F      SG+
Sbjct: 1285 GEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGV-PGFPGMKGPSGV 1343

Query: 371  P-TSDSRGPP----PTDPYGRPPPYD-----RGDYGPPG 399
            P ++   G P    P  P G P P       +GD GPPG
Sbjct: 1344 PGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPG 1382



 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 87/255 (34%), Positives = 99/255 (38%), Gaps = 43/255 (16%)

Query: 178  GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPG-----AVPGGDRFPGPAG-------PGG 225
            G+M   G  GPPG       P G  GR   PG      + G    PGP G       PG 
Sbjct: 896  GEMGMMGPPGPPG-------PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL 948

Query: 226  PPPPFPA-----GQTPPRPPLGPPGPPGPPGPPP----PGQVLPPPLAGPPNRGDRPPPP 276
            P PP P      G    +   G PG PG  GP      PG    P L+G P     PP P
Sbjct: 949  PGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL-PGPPGP 1007

Query: 277  VLFPGQPFGQPPLGPLPPGPPPPVPGYGPP-----PGPPPPQQGPPPPPGPFPPRPPGPL 331
               PG P GQP L   PPG    +   G P      GPP P   P  P  P  P   G  
Sbjct: 1008 KGNPGLP-GQPGLIG-PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 332  GPP-LTLAPPPHLPGP--PPGAP--PPAPHVNPAFFPP--PTNSGMPTSDSRGPPPTDPY 384
            G P ++    P LPGP   PG P  P  P +  +   P  P   G P +  +   P  P 
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 1125

Query: 385  GRPPPYDRGDYGPPG 399
               PP  +G  GPPG
Sbjct: 1126 TPGPPGPKGISGPPG 1140



 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 97/320 (30%), Positives = 110/320 (34%), Gaps = 111/320 (34%)

Query: 184 GKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-PGGPPPPFPAGQTPPRP--- 239
           G  GPPG       P G  G    PG++      PGP G PG P PP   G   P     
Sbjct: 141 GLQGPPG-------PPGIPGMKGEPGSIIMSS-LPGPKGNPGYPGPPGIQGLPGPTGIPG 192

Query: 240 PLGPPGPPG---PPGPP---------------PPGQVLPPPLAGPPN-----RGDRPPPP 276
           P+GPPGPPG   PPGPP               P G+     L GPP         + P  
Sbjct: 193 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 277 VLF----PGQPFGQPPLGPL----PPGPP---------------------------PPVP 301
           V F     G P  + P GP     PPGPP                           P +P
Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 302 GYGPPPGPP-----------PPQQGPPPPPGPFPPRP--------PGPLGPP-------- 334
           G    PG P               GPP PPG   PRP         G +G P        
Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372

Query: 335 ---LTLAPPPHLPGPPPGA--PPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP-- 387
                +  PP LPGPP  A   PP P   P       + G P     GPP  D  G+P  
Sbjct: 373 RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLD--GQPGA 430

Query: 388 -----PPYDRGDYGPPGREM 402
                PP   G + PP  E+
Sbjct: 431 PGLPGPPGPAGPHIPPSDEI 450



 Score = 72.8 bits (177), Expect = 8e-13
 Identities = 92/287 (32%), Positives = 103/287 (35%), Gaps = 72/287 (25%)

Query: 176 QSGQMSGEGKAGPPG------GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGG-PPP 228
           + GQ    G  GPPG      G+      +G  G    PG   G   FPG  GP G P P
Sbjct: 329 EKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE-KGERGFPGIQGPPGLPGP 387

Query: 229 PFPAGQTPPRPP--------LGPPGPPGPPGPPPP---GQVLPPPLAGPPNRGDRPPPPV 277
           P  A   PP PP         G  GPPG   P PP   GQ   P L GPP     P  P 
Sbjct: 388 PGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPG----PAGPH 443

Query: 278 LFPGQPFGQPPLGPLPPGPP--PPVPGYGPPPGPPPPQ------------QGPPPPPG-P 322
           + P     +P     PPGPP  P   G     G    +             GPP  PG P
Sbjct: 444 IPPSDEICEPG----PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499

Query: 323 FPPRPPGPLGPP--------LTLAPPPHLPGPP--PGAPP-PAPHVNPA---FFP----- 363
             P PPG LG P             P  LPG P  PGAP  P     P     FP     
Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD 559

Query: 364 --------PPTNSGMPTSDSRG--PPPTDPYGRPPPYD-RGDYGPPG 399
                    P   G+P +  +   P    P G P     +G+ GPPG
Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 61/161 (37%), Positives = 67/161 (41%), Gaps = 27/161 (16%)

Query: 183  EGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLG 242
            +G  GPPG       P G  G    PG +PG   FPG  GP G P    AG       +G
Sbjct: 1302 KGDQGPPGLQGNPGRP-GLNGMKGDPG-LPGVPGFPGMKGPSGVPGS--AGPEGEPGLIG 1357

Query: 243  PPGPPGPPGPPPPGQVL-----PPPLAGPPNRGDRPPP--PVLFPGQ--PFGQPPLGPLP 293
            PPGPPG PGP     ++     PP + G P     P P  P   PG   P G P    LP
Sbjct: 1358 PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP 1417

Query: 294  -----------PGPP--PPVPGYGPPPGPPPPQQGPPPPPG 321
                       PG P  P   G   PPGP    QGPP PPG
Sbjct: 1418 GFDGAGGRKGDPGLPGQPGTRGLDGPPGPDG-LQGPPGPPG 1457



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 36/108 (33%), Positives = 42/108 (38%), Gaps = 19/108 (17%)

Query: 176  QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQT 235
            + G +   G  G PG S ++   +G  G    PG  PG    PGP GP G P P      
Sbjct: 1352 EPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQ-PGLKGLPGPQGPQGLPGPTGPPGD 1410

Query: 236  PPRPPL----------------GPPGPPGPPGPPPPGQVLPPPLAGPP 267
            P R  L                G PG  G  GPP P  +  PP  GPP
Sbjct: 1411 PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPP--GPP 1456



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 37/91 (40%), Positives = 40/91 (43%), Gaps = 19/91 (20%)

Query: 183  EGKAGPPG-----GSSRAAFPQGGRGRGRFPGAV-----PGGDRFPGPAGPGGPP--PPF 230
            +G AGPPG     G      PQG +G    PG       PG +  PG  G GG    P  
Sbjct: 1375 KGDAGPPGIPGQPGLKGLPGPQGPQG---LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1431

Query: 231  PAGQTPPRPPLGPPGPPG---PPGPPPPGQV 258
            P GQ   R   GPPGP G   PPGPP    V
Sbjct: 1432 P-GQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1461



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 28/73 (38%), Positives = 29/73 (39%), Gaps = 2/73 (2%)

Query: 178  GQMSGEGKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQT 235
            GQ   +G  GP G  G      P G  GR   PG    G R   P  PG P      G  
Sbjct: 1385 GQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPP 1444

Query: 236  PPRPPLGPPGPPG 248
             P    GPPGPPG
Sbjct: 1445 GPDGLQGPPGPPG 1457


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score =  106 bits (264), Expect = 6e-23
 Identities = 79/210 (37%), Positives = 88/210 (41%), Gaps = 49/210 (23%)

Query: 226 PPPPFPAGQT--PPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPP---PPVLFP 280
           PPP  P  +T  PP PP  PP    PP     G+  PP   GP +  D P    PP   P
Sbjct: 351 PPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPP---GPVDATDLPKVQIPPPAHP 407

Query: 281 GQPFGQPPLGPLPPGPPPPVP-----------------GY----------GPPPGPPPPQ 313
             P  QPP  PLP  PPPP P                 GY          GP  G  PP 
Sbjct: 408 A-PVHQPP--PLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPA 464

Query: 314 QGPPP----PPGPFPPR-PPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNS 368
            GPP      P  +PP  PP P+ PP    PPP +P P PG PPP P  NP F PPP   
Sbjct: 465 YGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPR- 523

Query: 369 GMPTSDSRGPPPTDPYGRPPPYDRGDYGPP 398
            +P + +  P P    G PP      Y PP
Sbjct: 524 -LPPTHAVPPHPPPGLGLPP----ASYPPP 548



 Score = 99.4 bits (246), Expect = 8e-21
 Identities = 81/217 (37%), Positives = 88/217 (40%), Gaps = 49/217 (22%)

Query: 208 PGAVPGGDRFPGPAGP-GGPPPPFPAGQTP-PRPPLGPPGPPGPPGPPPPGQVLPPP--- 262
           P A P  DR P  A   G   PP P   T  P+  + PP  P P   PPP    PPP   
Sbjct: 366 PPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPP 425

Query: 263 -------------LAGP-------------PNRGDRPP---PPVLFPGQPFGQPPLGPLP 293
                        ++G              P+ G  PP   PP   P  P   PP  P P
Sbjct: 426 SSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPP 485

Query: 294 PGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPR-PPGPLGPPLTLAPPPHLPGPPPGAP- 351
           P PPPP     PPP  PPP  G PPPP  + P  PP P   P T A PPH   PPPG   
Sbjct: 486 PVPPPPASF--PPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPH---PPPGLGL 540

Query: 352 PPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPP 388
           PPA +  PA  P     G P      PPP  P G PP
Sbjct: 541 PPASYPPPAVPP----GGQPPV----PPPIPPPGMPP 569


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score =  105 bits (262), Expect = 1e-22
 Identities = 96/286 (33%), Positives = 111/286 (38%), Gaps = 78/286 (27%)

Query: 178  GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPP 237
            G+   +G  GP G        QG RG     G +PG    PGP+G  G P     G T P
Sbjct: 734  GEPGAKGAMGPAGPDGH----QGPRGEQGLTG-MPGIRGPPGPSGDPGKP-----GLTGP 783

Query: 238  RPPLGPPGPPGPPG----PPPPGQVLPPP------LAGPPNRGDRPPPPVLFPGQPFGQP 287
            + P G PG PG PG    P  PG+++         + GPP     PP  +  PG P    
Sbjct: 784  QGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPG----PPGAMGPPGPPGAPG 839

Query: 288  PLGPL-------------PPGPP----PPVPGYGPPPGP--PPPQ--QGPPPPPGPF--- 323
            P GP              PPGPP    PP P    PPGP  PP +   GPP PPG F   
Sbjct: 840  PAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSN 899

Query: 324  -------PPRPPGPLGPPLTLAPP--------PHLPG--------------PPPGAP-PP 353
                   PP PPGP GP     PP          LPG               PPG P P 
Sbjct: 900  SETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQ 959

Query: 354  APHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPG 399
             P  +      P   G+P+  S G   +  Y   PP   G  GPPG
Sbjct: 960  GPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPG 1005



 Score =  101 bits (252), Expect = 2e-21
 Identities = 98/281 (34%), Positives = 108/281 (38%), Gaps = 62/281 (22%)

Query: 178 GQMSGEGKAGPPG--GSSRAAFPQGGRG----RGRFPGAV--PGGDRFPGPAGPGGPPPP 229
           G    +G  GPPG  G      P+G  G    RG  PGAV  PG     GPAGP G   P
Sbjct: 695 GVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRG-LPGAVGEPGAKGAMGPAGPDGHQGP 753

Query: 230 FPAGQTPPRPPL-GPPGPPGPPGPP----PPGQVLPPPLAGPPNRGDRPPPPVLFPGQPF 284
                    P + GPPGP G PG P    P G    P   G P     P  P        
Sbjct: 754 RGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEG 813

Query: 285 GQPPLGPLPPGPPPPVPGYGPP--PGPPPPQ-----------QGPPPPP------GPFPP 325
                 P PPGPP  +   GPP  PGP  P            QGPP PP      GP  P
Sbjct: 814 SSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIP 873

Query: 326 RPPGPLGPP-------------------LTLAPPPHLPGPP-----PGAPPPAPHVNPAF 361
            PPGP GPP                     L+ PP  PGPP      G P P  H     
Sbjct: 874 GPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQG 933

Query: 362 FPPPTNSGMPT--SDSRGPP-PTDPYGRPPPYDRGDYGPPG 399
            P  + SG  +   + +GPP P  P G  P  D+GD G PG
Sbjct: 934 LPGFSTSGSSSFGLNLQGPPGPPGPQG--PKGDKGDPGVPG 972



 Score = 96.3 bits (238), Expect = 7e-20
 Identities = 98/290 (33%), Positives = 109/290 (37%), Gaps = 64/290 (22%)

Query: 176 QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP-PPFPAGQ 234
           + G M   G+AGPPG   +      G      P  VPG     G +G  GP  PP P G 
Sbjct: 625 REGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGL 684

Query: 235 TPPRPPLGPPG------PPGPPGPP-PPGQVLPPPLAGPPN-RGDRPPPPVLFPGQPFGQ 286
              R  +G PG      P GPPGP    G+  P  L G P  RG   P  V  PG     
Sbjct: 685 QGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRG--LPGAVGEPGAKGAM 742

Query: 287 PPLGPL-------------------PPGPP--PPVPGYGPPPGPP--------PPQQGPP 317
            P GP                    PPGP   P  PG   P GP         P  +G P
Sbjct: 743 GPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEP 802

Query: 318 PPPG-------------PFPPRPPGPLGPPLTLAPPPHLPGP--PPGAPPPAPHVNPAFF 362
             PG             P PP PPG +GPP     PP  PGP  P G P     +N    
Sbjct: 803 GAPGKIVTSEGSSMLTVPGPPGPPGAMGPP----GPPGAPGPAGPAGLPGHQEVLNLQGP 858

Query: 363 P-PPTNSGMPTSDSRGPP-PTDPYGRPPPYDRGDYGPPGREMDTARTPLS 410
           P PP   G P     GPP P  P G   P   G  GPPG  +  + T LS
Sbjct: 859 PGPPGPRGPPGPSIPGPPGPRGPPGEGLP---GPPGPPGSFLSNSETFLS 905



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 113/414 (27%), Positives = 129/414 (31%), Gaps = 160/414 (38%)

Query: 141 MDLLPKRELHGQNPVVTP------CNKQFLSQFEMQSRKTTQSGQMSGEGKAGP-PGGSS 193
           MD + K  L G  P           +     +  M  RK     Q +G  +  P P G  
Sbjct: 516 MDRIEKDRLQGMAPAAGADLDKIGLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDM 575

Query: 194 RAAFPQGGRGRGRFPGAVPGGDRFPGPAGP-------GGPPPPFPAGQTPPRPPLGP--- 243
            +  P+G RG    PG +PG    PGP GP       G P    P GQ     P+GP   
Sbjct: 576 GSPGPKGDRGFPGTPG-IPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGE 634

Query: 244 -----------------PGPPGPPGPP----PPGQVLPPPLAGPPN-------------- 268
                            PGP GPPG P    P G    P   GPP               
Sbjct: 635 AGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLP 694

Query: 269 --RGDRPP--PP--------------------------VLFPGQPFGQPPLGP------- 291
             +GD+ P  PP                          V  PG      P GP       
Sbjct: 695 GVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPR 754

Query: 292 ------------LPPGP--PPPVPGYGPPPGPP--------PPQQGPPPPPG-------- 321
                        PPGP   P  PG   P GP         P  +G P  PG        
Sbjct: 755 GEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGS 814

Query: 322 -----PFPPRPPGPLGPPLTLAPPPHLPGP-----------------PPGAPPPAPHVNP 359
                P PP PPG +GPP     PP  PGP                 PPG P P     P
Sbjct: 815 SMLTVPGPPGPPGAMGPP----GPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGP 870

Query: 360 AFFPPPTNSGMPTSDSRGPPP-------------TDPYGRP-PPYDRGDYGPPG 399
           +   PP   G P     GPP              + P G P PP  +GD GPPG
Sbjct: 871 SIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPG 924



 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 88/261 (33%), Positives = 97/261 (37%), Gaps = 105/261 (40%)

Query: 178  GQMSGEGKAGPPG------GSSRAAFPQGGRGRGRFPGAV--PGGDRFPGPAGPGGPP-- 227
            G+   +G+ G PG      GSS    P    G    PGA+  PG    PGPAGP G P  
Sbjct: 794  GRPGIKGEPGAPGKIVTSEGSSMLTVP----GPPGPPGAMGPPGPPGAPGPAGPAGLPGH 849

Query: 228  --------PPFPAG-QTPPRPPL-GPPGPPGPPG------PPPPGQVL---------PPP 262
                    PP P G + PP P + GPPGP GPPG      P PPG  L         PP 
Sbjct: 850  QEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPG 909

Query: 263  LAGPPN-RGDRPPPPVL-------FPG------QPFGQPPLGPL-PPGPPPP-------- 299
              GPP  +GD+ PP           PG        FG    GP  PPGP  P        
Sbjct: 910  PPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPG 969

Query: 300  VPG-YGPPPGP-------------PPPQQGPPPPPGPF---------------------- 323
            VPG  G P GP             PP   GPP PPG                        
Sbjct: 970  VPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRS 1029

Query: 324  -------PPRPPGPLGPPLTL 337
                   PP PPGP GP  T+
Sbjct: 1030 YLSGVQGPPGPPGPPGPVTTI 1050



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 46/147 (31%), Positives = 53/147 (36%), Gaps = 31/147 (21%)

Query: 184  GKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPL 241
            G  GPPG  G      P+G +G    PG    G    G    G P PP P G   P+   
Sbjct: 909  GPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQG---PKGDK 965

Query: 242  GPPGPPG----PPGPPPPGQVLPPPLAGPPNRGDRPPPP--VLFPGQPFGQ--------- 286
            G PG PG    P GP   G      ++GPP     P PP  +   GQ   Q         
Sbjct: 966  GDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSD 1025

Query: 287  -----------PPLGPLPPGPPPPVPG 302
                       PP  P PPGP   + G
Sbjct: 1026 SIRSYLSGVQGPPGPPGPPGPVTTITG 1052



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 66/232 (28%), Positives = 83/232 (35%), Gaps = 48/232 (20%)

Query: 241  LGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPP--- 297
            +GP GPPGPPG    G +L    A   +R       +L      G     P PPGPP   
Sbjct: 1105 MGPRGPPGPPGASGDGSLLSLDYAELSSR-------ILSYMSSSGISIGLPGPPGPPGLP 1157

Query: 298  -------------PPVPGYGPPPGPPPPQQGPPPPPG-PFPPRPPGPLGPPLTLAPPPHL 343
                             G   PPGPP    GPP  PG  +       L   L  A    +
Sbjct: 1158 GTSYEELLSLLRGSEFRGIVGPPGPP----GPPGIPGNVWSSISVEDLSSYLHTAGLSFI 1213

Query: 344  PGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDS--------RGPPPTDPYGRPPPYDRGDY 395
            PGPP    PP P   P             SDS           P    +   PP   G  
Sbjct: 1214 PGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQ 1273

Query: 396  GPPGREMDTARTPLSEAEFEEIMNRNRAISSSAISRAVSDASAGDYGSAIET 447
            GPPG     +R   ++A      + +R  SSS+ S +V   S+  Y S++ T
Sbjct: 1274 GPPG----DSRLLSTDA------SHSRGSSSSSHSSSVRRGSS--YSSSMST 1313



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 52/179 (29%), Positives = 58/179 (32%), Gaps = 71/179 (39%)

Query: 219  GPAGPGGPPPPFPAG-----------------QTPPRPPLGPPGPPGPPGPPPPG-QVLP 260
            GP GP GPP     G                  +     +G PGPPGPPG P    + L 
Sbjct: 1106 GPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELL 1165

Query: 261  PPLAGPPNRG----DRPPPPVLFPGQPFGQPPLGPLP-----------PGPPPPVPGYGP 305
              L G   RG      PP P   PG  +    +  L            PGPP        
Sbjct: 1166 SLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPP-------G 1218

Query: 306  PPGPPPPQQGPPPPPGPF------------------------------PPRPPGPLGPP 334
            PPGPP P +GPP   G                                PP PPGP GPP
Sbjct: 1219 PPGPPGP-RGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPP 1276



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 39/122 (31%), Positives = 42/122 (34%), Gaps = 33/122 (27%)

Query: 214  GDRFPGPAGPGGPP-PPFPAGQTPPRPPL----------------GPPGPPGPPGPPPPG 256
            G  F G  GP GPP PP   G       +                GPPGPPGPPGP    
Sbjct: 1170 GSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGP---- 1225

Query: 257  QVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGY-GPPPGPPPPQQG 315
                    GPP                F    +  L     P V  +   PPGPP P QG
Sbjct: 1226 -------RGPPGVSGALATYAAENSDSFRSELISYL---TSPDVRSFIVGPPGPPGP-QG 1274

Query: 316  PP 317
            PP
Sbjct: 1275 PP 1276



 Score = 36.6 bits (83), Expect = 0.061
 Identities = 31/93 (33%), Positives = 36/93 (38%), Gaps = 13/93 (13%)

Query: 169  MQSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGG-----DRFPGPAGP 223
            MQ +   Q    + +G  G PG       PQG  G  +   A         D F      
Sbjct: 1384 MQRQGLLQGMAYTVQGPPGQPG-------PQGPPGISKVFSAYSNVTADLMDFFQTYGAI 1436

Query: 224  GGPPPPFPAGQTP-PRPPLGPPGPPGPPGPPPP 255
             GPP       TP P+   GP GPPG PGPP P
Sbjct: 1437 QGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGP 1469



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 33/103 (32%), Positives = 40/103 (38%), Gaps = 9/103 (8%)

Query: 153  NPVVTPCNKQFLSQFEMQSRKTTQSGQMSGEGKAGPPGGSSR-AAFPQGGRGRGRF---P 208
            N +    ++    Q  +Q    T  G     G  GPPG S   +A+         F    
Sbjct: 1374 NELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTY 1433

Query: 209  GAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPG 251
            GA+ G    PG  G  G P P   G   P  P G PGPPGP G
Sbjct: 1434 GAIQGP---PGQKGEMGTPGP--KGDRGPAGPPGHPGPPGPRG 1471



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 30/92 (32%), Positives = 36/92 (39%), Gaps = 17/92 (18%)

Query: 242  GPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVP 301
            GPPG PGP GPP   +V         +        ++   Q +G         GPP    
Sbjct: 1399 GPPGQPGPQGPPGISKVF--------SAYSNVTADLMDFFQTYGAIQ------GPPGQKG 1444

Query: 302  GYGPPPGPPPPQQGPPPPPG-PFPPRPPGPLG 332
              G P   P   +GP  PPG P PP P G  G
Sbjct: 1445 EMGTPG--PKGDRGPAGPPGHPGPPGPRGHKG 1474



 Score = 33.1 bits (74), Expect = 0.68
 Identities = 26/79 (32%), Positives = 31/79 (39%), Gaps = 24/79 (30%)

Query: 218  PGPAGPGGPP--------------------PPFPAGQTPP--RPPLGPPGPPGPPGPP-P 254
            PG  GP GPP                      + A Q PP  +  +G PGP G  GP  P
Sbjct: 1401 PGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGP 1460

Query: 255  PGQVLPP-PLAGPPNRGDR 272
            PG   PP P      +GD+
Sbjct: 1461 PGHPGPPGPRGHKGEKGDK 1479



 Score = 33.1 bits (74), Expect = 0.68
 Identities = 23/54 (42%), Positives = 24/54 (44%), Gaps = 18/54 (33%)

Query: 198  PQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPG 251
            P G +G    PG  P GDR  GPAGP G P              GPPGP G  G
Sbjct: 1439 PPGQKGEMGTPG--PKGDR--GPAGPPGHP--------------GPPGPRGHKG 1474


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score =  105 bits (261), Expect = 1e-22
 Identities = 89/265 (33%), Positives = 103/265 (38%), Gaps = 62/265 (23%)

Query: 189 PGGSSRAAFPQGGRGRG------RFPGAVPGGDRFPGPAGP--GGPPPPFPAGQT-PPRP 239
           P G    A  + G+G G      R P     G   P PA P  G       A +T PPRP
Sbjct: 111 PAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIP-PASPRLGNTSEAHGAARTAPPRP 169

Query: 240 PLGPPGPPGPPGPPPPGQVLPPPL----------AGPPNRGDRPPPPVLFPGQPFGQPPL 289
            +  P PP PP PPPP   LPPPL            PP    +   PV+ P  P   PP 
Sbjct: 170 NVPAPPPPTPPPPPPP---LPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPP 226

Query: 290 GPLPPGPPPPVPGYGP---------------PPGPPPPQQGPP--------PPPGPF--- 323
            P PP  PPP+P                   PP PPP    PP         P  P    
Sbjct: 227 PPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDA 286

Query: 324 --PPRPPGPLGPPLTLAPPPHLPGPP-PG------APPPAPHVNPAFFPPPTNSGMPTSD 374
             PP PP PL P  + +P   LP PP PG       PPP P  +P+F  PP  +G     
Sbjct: 287 QEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQAL- 345

Query: 375 SRGPPPTDPYGRPPPYDRGDYGPPG 399
              P P  P G  P   +  +G PG
Sbjct: 346 ---PAPPAPPGSQPFLQKKRHGRPG 367



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 71/210 (33%), Positives = 77/210 (36%), Gaps = 47/210 (22%)

Query: 218 PGPAGPGGPP---PPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPP 274
           PGP   G  P   PP P    PP PP  P  PP PP      + + P LA P +    PP
Sbjct: 204 PGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLA-PLHLPPIPP 262

Query: 275 PPVLFPGQPFGQP-----PLGPL-----PPGPPPPVPGYG-------------------- 304
           P  L P  P G P     P  P      PP PPPP+P Y                     
Sbjct: 263 PLPLLP--PCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSS 320

Query: 305 --PPPGPP--PPQQGPPPPPGPFP-PRPPGPLGPPLTLAPPPH-LPGPPPGA--PPPAPH 356
             PPP PP  P  Q PP   G    P PP P G    L    H  PG   G   PPPAP 
Sbjct: 321 ETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAP- 379

Query: 357 VNPAFFPPPTNSGMPTSDSRGPPPTDPYGR 386
             PA  P    S      +   P   P G+
Sbjct: 380 --PARSPTTELSSKSQQATAWTPTQQPGGQ 407



 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 74/261 (28%), Positives = 81/261 (31%), Gaps = 100/261 (38%)

Query: 223 PGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNR------------- 269
           P  PPPP P    PP PPLG P PP P  PP          A P  R             
Sbjct: 4   PPPPPPPLP----PPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRL 59

Query: 270 ------GDRPPPPV---------------------------LFPG-----QPFGQPPL-- 289
                  DR  P +                           LF G     +P GQ  +  
Sbjct: 60  RKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAG 119

Query: 290 -----GPLPPGPPPPVPG---YGP--PPGPP---------------PPQQGPPPPPGPFP 324
                GP    P P +P     GP  PP  P               PP+   P PP P P
Sbjct: 120 GKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP 179

Query: 325 PRPPGPLGPPLTLAPP-----------------PHLPGPPPGAPPPAPHVNPAFFPPPTN 367
           P PP PL PPL  + P                 P +  P P APPP P   P   PPP  
Sbjct: 180 PPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPP-TPPPLP 238

Query: 368 SGMPTSDSRGPPPTDPYGRPP 388
                SD    P   P   PP
Sbjct: 239 PASVLSDKAVKPQLAPLHLPP 259



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 57/206 (27%), Positives = 60/206 (29%), Gaps = 61/206 (29%)

Query: 198 PQGGRGRGRFPGAVPGGDRFPGPAGPGGPP--PPFPAGQT-------------------P 236
           P G   +G  P   P     P P  P  PP  PP P                       P
Sbjct: 203 PPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPP 262

Query: 237 PRPPLGPPGPPG--------------PPGPPPPGQVLPP--------PLAGPP----NRG 270
           P P L P G PG              PP PPPP   LPP         L  PP    N  
Sbjct: 263 PLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPP---LPPYASCSPRASLPAPPLPGVNSS 319

Query: 271 DRPPPPVLFPGQPFGQPPLG------PLPPGPPPPVP-----GYGPPPGPPPPQQGPPPP 319
              PPP+      F  PP        P PP PP   P      +G P         PP P
Sbjct: 320 SETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAP 379

Query: 320 PGPFPPRPPGPLGPPLTLAPPPHLPG 345
           P   P           T   P   PG
Sbjct: 380 PARSPTTELSSKSQQATAWTPTQQPG 405



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 58/212 (27%), Positives = 65/212 (30%), Gaps = 77/212 (36%)

Query: 237 PRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPL------- 289
           P PP  PP PP PP PPP G   PPP + PP   D      L    P G+  L       
Sbjct: 2   PVPP--PPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSS---LRRADPKGRSALLADIQQG 56

Query: 290 ------GPLPPGPPPPV---PGYGPPPGPPPPQQGPPPPP-------GPFP--------- 324
                   +     P +    G     G     +G   PP       G FP         
Sbjct: 57  TRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRD 116

Query: 325 ----------------PRPP-----GPLGPPL---------------TLAPPPHLPGPPP 348
                           PR P     GPL PP                T  P P++P PPP
Sbjct: 117 VAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPP 176

Query: 349 GAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP 380
             PPP P       PPP  S  P       PP
Sbjct: 177 PTPPPPPPP----LPPPLPSSSPIKTPLVSPP 204



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 18/34 (52%), Positives = 19/34 (55%), Gaps = 4/34 (11%)

Query: 292 LPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPP 325
           +P  PPPP P     P PPPP   PPPPP   PP
Sbjct: 1   MPVPPPPPPP----LPPPPPPLGAPPPPPPSAPP 30



 Score = 33.5 bits (75), Expect = 0.52
 Identities = 20/47 (42%), Positives = 22/47 (46%), Gaps = 3/47 (6%)

Query: 341 PHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTS-DSRGPPPTDPYGR 386
           P  P PPP  PPP P +     PPP  S  P S D+      DP GR
Sbjct: 2   PVPPPPPPPLPPPPPPLGAP--PPPPPSAPPVSTDTSSLRRADPKGR 46


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  104 bits (260), Expect = 2e-22
 Identities = 97/283 (34%), Positives = 109/283 (38%), Gaps = 59/283 (20%)

Query: 173  KTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPG-----AVPGGDRFP--------- 218
            K    G   G+G AGPPG       P G +G   FPG       PG D  P         
Sbjct: 929  KPGPKGNSGGDGPAGPPGERG----PNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGET 984

Query: 219  ---GPAGPGGPP----PPFPAGQTPPRPPLGPPGPPGPPGPP-------PPGQVLPPPLA 264
               G  GP GPP    P  P G+T P    G PGPPGPPG           G    P  A
Sbjct: 985  GFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPA 1044

Query: 265  GPPNRGDRPPPPVLFPGQPFGQPPLGPL-------PPGPPPPV--PGYGPPPGPP----- 310
            G P + D PP    FPG      P+G L       PPGPP P   PG   P G       
Sbjct: 1045 GLPGK-DGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGI 1103

Query: 311  PPQQGPPPPPGPF----PPRPPGPLGPPLT--LAPPPHLPGPPPGAPPPAPHVNPAFFPP 364
            P + GP  PPGP      P   GP GP     L  P  LPGP     PP    +      
Sbjct: 1104 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGE 1163

Query: 365  PTNSGMP-TSDSRGPP----PTDPYGRPPPYDR-GDYGPPGRE 401
            P   G       +GPP    P  P G+P P    G+ GP G++
Sbjct: 1164 PGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQ 1206



 Score =  102 bits (253), Expect = 1e-21
 Identities = 101/298 (33%), Positives = 114/298 (38%), Gaps = 74/298 (24%)

Query: 178  GQMSGEGKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP----PPFP 231
            G    EG  GPPG  GS     P G  G    PG  PG    PGPAG  G P    P  P
Sbjct: 1072 GLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGR-PGPQGPPGPAGEKGAPGEKGPQGP 1130

Query: 232  AGQTPPRPPLGPPGPPGPPGPP----PPGQVLPPPLAGPP-NRGDRPPPPVLFPGQPFGQ 286
            AG+   + P+G PGP GP GPP      G++  P   G   ++G++ PP    P  P GQ
Sbjct: 1131 AGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQ 1190

Query: 287  P-PLG----PLP------------------PGPPPPVPGYGPPPGPPPP--------QQG 315
            P P G    P P                  PGPP PV G    PGPP          Q G
Sbjct: 1191 PGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPV-GLQGLPGPPGEKGETGDVGQMG 1249

Query: 316  PPPPPGPFPPR----PPGPLGPPLTLAPPPHL-----------PGPPPGAPPPAPHVN-- 358
            PP PPGP  P       GP GPP  +  P  +           PG P    PP P     
Sbjct: 1250 PPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERG 1309

Query: 359  -------PAFFPPPTNSGMPTSDS-RGPP-----PTDPYGRPPPYDRGDYGPPGREMD 403
                        PP   G P  D  +G P     P DP     P   G  GPPG + D
Sbjct: 1310 EKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGD 1367



 Score =  100 bits (250), Expect = 3e-21
 Identities = 109/318 (34%), Positives = 121/318 (38%), Gaps = 93/318 (29%)

Query: 176  QSGQMSGEGKAGPPG-----------GSSRAAFPQGGRGR-GRFPGAVPGGDR-FPGPAG 222
            Q G    +G+ GPPG           G S A    G RG+ G F      G R FPGP G
Sbjct: 1166 QKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPG 1225

Query: 223  PGG----PPPPFPAGQTPPRPPLGPPGPPGPPGP-----------PP------------- 254
            P G    P PP   G+T     +GPPGPPGP GP           PP             
Sbjct: 1226 PVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKG 1285

Query: 255  -PGQVLPPPL---AGPPN-RGDR-------------PPPPVLFPGQ--PFGQP-PLG--- 290
             PG+   P L    GPP  +G+R             PP P   PG   P G P P+G   
Sbjct: 1286 EPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPG 1345

Query: 291  -PLPPGPPPPVPGYGPP----PGPPPPQQGPPPPPG-PFPPRPPGPLGPPLTLAP----- 339
             P PPG P P    GPP        P Q G P P G P P  PPG  GPP    P     
Sbjct: 1346 DPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQG 1405

Query: 340  ------------PPHLPGP--PPGAP-PPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPY 384
                        PP   GP  P GAP  P P        P    G+P S     PP  P 
Sbjct: 1406 EKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPP-GPM 1464

Query: 385  GRPP-PYDRGDYGPPGRE 401
            G P  P  +GD GP G +
Sbjct: 1465 GPPGLPGLKGDSGPKGEK 1482



 Score =  100 bits (248), Expect = 5e-21
 Identities = 90/254 (35%), Positives = 96/254 (37%), Gaps = 53/254 (20%)

Query: 173  KTTQSGQMSGEGKAGP--PGGSSRAAFPQGGRGRGRFPGAV-----PGGDRFPGPAGPGG 225
            +T   GQM   G  GP  P G+  A  PQG  G    PGAV     PG    PG  G GG
Sbjct: 1241 ETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGG 1300

Query: 226  PPPPF----PAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPG 281
            PP P       G++ P    GPPGP GPPG   P             +G   P PV FPG
Sbjct: 1301 PPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGP-------------KGS--PGPVGFPG 1345

Query: 282  QPFGQPPLGPLPPGPPPPVPGYGPPPGP----PPPQQGPPPPPG-PFPPRPPGPLGPPLT 336
             P         PPG P P    GPP        P Q G P P G P P  PPG  GPP  
Sbjct: 1346 DPG--------PPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGP 1397

Query: 337  LAPPPH-----------LPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYG 385
              P              L GPP    P  P   P    P    G+P        P  P  
Sbjct: 1398 AGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGP 1457

Query: 386  RPPPYDRGDYGPPG 399
              PP   G  GPPG
Sbjct: 1458 DGPP---GPMGPPG 1468



 Score = 97.1 bits (240), Expect = 4e-20
 Identities = 96/283 (33%), Positives = 111/283 (39%), Gaps = 75/283 (26%)

Query: 177  SGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-PGGPPPPFPAGQT 235
            +G+  G G  G PG   +   P G RG  R P  + G    PGP G  GG  P  P G+ 
Sbjct: 894  NGEKGGRGTPGKPGPRGQRG-PTGPRGE-RGPRGITGK---PGPKGNSGGDGPAGPPGER 948

Query: 236  PPRPPLGPPGPPGPPGPP-PPGQVLPPPLAGPPNR----------GDRPPPPVLFPGQPF 284
             P  P GP G PGP GPP PPG+     L G P +          G   PP V+ P  P 
Sbjct: 949  GPNGPQGPTGFPGPKGPPGPPGK---DGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPT 1005

Query: 285  GQP-PLG----PLPPGPP--PPVPGYG--------PPPGPPPPQQGPP---------PPP 320
            G+  P+G    P PPGPP    +PG          P P   P + GPP           P
Sbjct: 1006 GETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLP 1065

Query: 321  GPF----------PPRPPGPLGPPLTLAP-----PPHLPGPPPGAPPPAPHVNPAFFPPP 365
            GP           PP PPGP G P    P     P  +PG P    PP          P 
Sbjct: 1066 GPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPG---------PA 1116

Query: 366  TNSGMP-TSDSRGPPPTD----PYGRPPPYDRGDYGPPGREMD 403
               G P     +GP   D    P G P P   G  GPPG + D
Sbjct: 1117 GEKGAPGEKGPQGPAGRDGLQGPVGLPGP--AGPVGPPGEDGD 1157



 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 87/273 (31%), Positives = 99/273 (36%), Gaps = 73/273 (26%)

Query: 176  QSGQMSGEGKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP------ 227
            + G+    G AGPPG  G      P+G  G   FPG  PG    PGPAG  GPP      
Sbjct: 1310 EKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGD-PGPPGEPGPAGQDGPPGDKGDD 1368

Query: 228  -------PPFPAGQTPPRPPLGPPGPPGPPGPP----------------PPGQVLPPPLA 264
                    P P G+  P  P G  GPPGP GP                 PPG+  P    
Sbjct: 1369 GEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQ 1428

Query: 265  GPPNRGDRP-----PPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGP---------- 309
            G P +         P PV   G P    P GP  P  PP +PG     GP          
Sbjct: 1429 GAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLI 1488

Query: 310  ----PPPQQGP------PPPPGPFPPR-------PPGPLGPPLTLAPPPHLPGPP----- 347
                PP +QG       P P G   P+       P GP+GPP     PP LPGPP     
Sbjct: 1489 GLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPP----GPPGLPGPPGPKGA 1544

Query: 348  PGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP 380
             G+  P      A  P P     P  +   P P
Sbjct: 1545 KGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLP 1577



 Score = 90.9 bits (224), Expect = 3e-18
 Identities = 100/320 (31%), Positives = 108/320 (33%), Gaps = 109/320 (34%)

Query: 184  GKAGPPG-----GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP----------- 227
            G  GPPG     G+     PQG  GR    G V      PGPAGP GPP           
Sbjct: 1108 GPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVG----LPGPAGPVGPPGEDGDKGEIGE 1163

Query: 228  -----------PPFPAGQTPPRPPLGPPGPP---GPPG-------------------PPP 254
                          P G T P+ P+G PGP    G PG                   P P
Sbjct: 1164 PGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGP 1223

Query: 255  PGQVLPPPLAGPPNR-------GDRPPPPVLFPGQPFGQPPLGPLPPGPP---------- 297
            PG V    L GPP         G   PP    P  P G P     P GPP          
Sbjct: 1224 PGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADG-PQGPPGGIGNPGAVG 1282

Query: 298  ----------PPVPGYGPPPGP-----------PPPQQGPPPPPGP----FPPRPPGPLG 332
                      P +PG G PPGP           P    GPP P GP     P   PGP+G
Sbjct: 1283 EKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVG 1342

Query: 333  PPLTLAPPPHLPGP-----PPGAPPPAPHVNPAFFPPPTNSGMPTS--DSRGPP-PTDPY 384
             P    PP   PGP     PPG             P PT    P+     RGPP P  P 
Sbjct: 1343 FPGDPGPPGE-PGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPE 1401

Query: 385  GRP----PPYDRGDYGPPGR 400
            GR        + G  GPPG+
Sbjct: 1402 GRQGEKGAKGEAGLEGPPGK 1421



 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 92/279 (32%), Positives = 107/279 (38%), Gaps = 61/279 (21%)

Query: 164 LSQFEMQSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGP 223
           +S  E Q++   Q  +++  G AGP G + R   P G  G G   G        PG  GP
Sbjct: 539 VSAQESQAQAILQQARLALRGPAGPMGLTGRPG-PVGPPGSGGLKGE-------PGDVGP 590

Query: 224 GGPP----PPFPAGQTPPRPPLGPPGPPGPPGPPPP----------------GQVLPPPL 263
            GP     PP PAG+   R   G  G  G PG   P                G    P  
Sbjct: 591 QGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGP 650

Query: 264 AGPPN-------RGDRPPP-PVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQ-- 313
           +GPP        RGD     P   PG+P  +  LGP  P  PP  PG     G P P+  
Sbjct: 651 SGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGN 710

Query: 314 ---QGPPPPPGPFP-------PRPPGPLGPPLTLAP--PPHLPGPPPGAPPPAPHVNPAF 361
              QG P PPG          P P G +GPP    P   P LPG P    PP    +P  
Sbjct: 711 VGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPG---HPGK 767

Query: 362 FPPPTNSGMPTSDSRGPP-PTDPYGRPPPYDRGDYGPPG 399
             PP   G      +GPP P  P G P P  RG  G  G
Sbjct: 768 EGPPGEKG-----GQGPPGPQGPIGYPGP--RGVKGADG 799



 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 94/291 (32%), Positives = 107/291 (36%), Gaps = 69/291 (23%)

Query: 176  QSGQMSGEGKAGPPGGSSRAAFP--------QGGRGRGRFPGAVPGGDRFPGPAG-PGGP 226
            + G     G  GPPG   +   P        QG +G   FPG  PG +   G  G PG P
Sbjct: 848  RGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPG-FPGANGEKGGRGTPGKP 906

Query: 227  PPPFPAGQTPPRPPLGPPGPPGPPGPP----------PPGQVLPPPLAGP-----PNRGD 271
             P    G T PR   GP G  G PGP           PPG+  P    GP     P    
Sbjct: 907  GPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPP 966

Query: 272  RPPPPVLFPGQPFGQPPLG----PLPPGPPPPVPGYGPP-----------PGP--PPPQQ 314
             PP     PG P  +   G      PPGPP  V   GP            PGP  PP +Q
Sbjct: 967  GPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQ 1026

Query: 315  GPPPPPG-------PFPPRPPGPLGPPLTLAPPPH--LPGP-----------PPGAPPPA 354
            G P   G       P P   PG  GPP     P    LPGP           PPG  PP 
Sbjct: 1027 GLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPG--PPG 1084

Query: 355  PHVNPAFFPPPTNSGMPTSDSRGPPPTDPYG----RPPPYDRGDYGPPGRE 401
            P  +P    P   +G P      P P  P G    +  P ++G  GP GR+
Sbjct: 1085 PAGSPGERGPAGAAG-PIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1134



 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 75/205 (36%), Positives = 87/205 (42%), Gaps = 47/205 (22%)

Query: 174  TTQSGQMSGEGKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-PGGPPP-- 228
            T + G     GK GPPG  G       +G +G     G  PG     GP G PG P P  
Sbjct: 1380 TGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGP-PGKTGPIGPQGAPGKPGPDG 1438

Query: 229  ----PFPAGQT--PPRP-PLGPPGPPGPPGPP-------PPGQVLPPPLAG---PPN--- 268
                P P G+   P  P P GPPGP GPPG P       P G+   P L G   PP    
Sbjct: 1439 LRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQG 1498

Query: 269  -RGDRPPPPVLFPGQPFGQP----PLGPLPPGPPPPVPGYGPPPGP-----------PPP 312
             +GDR  P       P G+     P GP+ P  PP +PG   PPGP           P  
Sbjct: 1499 EKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPG---PPGPKGAKGSSGPTGPKG 1555

Query: 313  QQGPPPPPGPFPPRPPGPLGPPLTL 337
            + G P PPGP  P PPG +  PL +
Sbjct: 1556 EAGHPGPPGP--PGPPGEVIQPLPI 1578



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 92/300 (30%), Positives = 104/300 (34%), Gaps = 80/300 (26%)

Query: 178  GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPG-----AVPGGDRFPGPAGPGGPP----- 227
            G+  G+G  GP G       P+G +G     G        G D FPG  G  G       
Sbjct: 772  GEKGGQGPPGPQGPIGYPG-PRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGE 830

Query: 228  --PPFPAGQTPPRPPLGPPGPPGPPGP--PP--PGQVLPPPLAGPPNRGDRPPPPVLFPG 281
              PP P G+  P  P G  GP G PGP  PP   G++  P L G P R   P   + FPG
Sbjct: 831  IGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGR-QGPKGSIGFPG 889

Query: 282  QPFGQPPLGPL-PPGPPPPVPGYGP--------------PPGP-----------PPPQQG 315
             P      G    PG P P    GP               PGP           PP ++G
Sbjct: 890  FPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERG 949

Query: 316  PPPPPGPFP-PRPPGPLGPPLTLAPPPH--------------LPGPPPGAPPPAP----- 355
            P  P GP   P P GP GPP     P H               PGPP    P  P     
Sbjct: 950  PNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETG 1009

Query: 356  ----HVNPAFFPPPTNSGMP-------TSDSRGPPPTDPYGRPP-----PYDRGDYGPPG 399
                  +P    PP   G+P       T    GP        PP     P DRG  GP G
Sbjct: 1010 PMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVG 1069



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 94/318 (29%), Positives = 103/318 (32%), Gaps = 101/318 (31%)

Query: 178  GQMSGEGKAGPPG-----------GSSRAAFPQGGRGRGRFPG--AVPGGDRFPGPAGPG 224
            G +  +G+ GPPG           G   A  P G +G    PG   +PG D  PG  G  
Sbjct: 709  GNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKE 768

Query: 225  GPP-------PPFPAGQ---------------------------------------TPPR 238
            GPP       PP P G                                           R
Sbjct: 769  GPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDR 828

Query: 239  PPLGPPGPPGPPGPPPP----GQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG---- 290
              +GPPGP G  GP  P    G    P   GPP    +   P L PG P  Q P G    
Sbjct: 829  GEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGL-PGYPGRQGPKGSIGF 887

Query: 291  PLPPGPPPPVPGYGPPPGP-PPPQQGPPPPPGPFPPR-------------PPGPLGPPLT 336
            P  PG      G G P  P P  Q+GP  P G   PR               GP GPP  
Sbjct: 888  PGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGE 947

Query: 337  LAP-----PPHLPGP--PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPP-------PTD 382
              P     P   PGP  PPG  PP     P    P            GPP       P  
Sbjct: 948  RGPNGPQGPTGFPGPKGPPG--PPGKDGLPGH--PGQRGETGFQGKTGPPGPPGVVGPQG 1003

Query: 383  PYGRPPPY-DRGDYGPPG 399
            P G   P  +RG  GPPG
Sbjct: 1004 PTGETGPMGERGHPGPPG 1021



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 84/312 (26%), Positives = 96/312 (30%), Gaps = 118/312 (37%)

Query: 198 PQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPG------ 251
           P+G +G+   P  +  G    GP GP GP     AG   P   +GP G  G PG      
Sbjct: 448 PRGEKGQKGEPAIIEPGMLIEGPPGPEGP-----AGLPGPPGTMGPTGQVGDPGERGPPG 502

Query: 252 ----------PPPPGQVLPPPL------------------------------------AG 265
                     P PPG +L  P                                     AG
Sbjct: 503 RPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAG 562

Query: 266 PPNRGDR-----PPPPVLFPGQPFGQPPLGPL----PPGPPPP--------------VPG 302
           P     R     PP      G+P    P GP     PPGP                 +PG
Sbjct: 563 PMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPG 622

Query: 303 YGPPPGP-----------------PPPQQGPPPPPGP----------FPPRPPGPLGPPL 335
              P G                   P   GPP PPG            P   PG  GP  
Sbjct: 623 QTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRG 682

Query: 336 TLAP--PPHLPGPP-----PGAPPPAPHVNPAFFP-PPTNSGMPTSDSRGPPPTDPYGRP 387
            L P  PP  PGPP      G P P  +V P   P PP   G P +    P P    G  
Sbjct: 683 LLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGL-PGPQGAIG-- 739

Query: 388 PPYDRGDYGPPG 399
           PP ++G  G PG
Sbjct: 740 PPGEKGPLGKPG 751



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 52/168 (30%), Positives = 62/168 (36%), Gaps = 13/168 (7%)

Query: 236 PPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPN-RGDRPPPPVLFPGQPFGQPPLGPLPP 294
           P   P   P   GP G P     +   + GP   +G +  P ++ PG     PP GP  P
Sbjct: 419 PYYDPTSSPSEIGP-GMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPP-GPEGP 476

Query: 295 GPPPPVPGYGPPPGP--PPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPP 352
              P  PG   P G    P ++GPP  PG   P   G  GPP T+   P   G    A  
Sbjct: 477 AGLPGPPGTMGPTGQVGDPGERGPPGRPGL--PGADGLPGPPGTMLMLPFRFGGGGDAGS 534

Query: 353 PAPHVNPAFFPPPTNSGMPTSDSRGPP-PTDPYGRPPPYDRGDYGPPG 399
             P V+                 RGP  P    GRP     G  GPPG
Sbjct: 535 KGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRP-----GPVGPPG 577



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 32/88 (36%), Positives = 38/88 (43%), Gaps = 10/88 (11%)

Query: 176  QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAV--PGGDRFPGPAGP----GGPPPP 229
            + G+    G  GP G S     P+G +G     G +  PG    PGP GP    G   P 
Sbjct: 1496 EQGEKGDRGLPGPQGSSG----PKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPT 1551

Query: 230  FPAGQTPPRPPLGPPGPPGPPGPPPPGQ 257
             P G+     P GPPGPPG    P P Q
Sbjct: 1552 GPKGEAGHPGPPGPPGPPGEVIQPLPIQ 1579


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  103 bits (256), Expect = 5e-22
 Identities = 94/253 (37%), Positives = 100/253 (39%), Gaps = 43/253 (16%)

Query: 184 GKAGPPG--GSSRAAFPQGGRGRGRFPG--AVPG---GDRFPGPAG----PGGPPPPFPA 232
           G AGPPG  G   AA P G  G    PG   +PG   G   PGP G    PGGP      
Sbjct: 696 GGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVP 755

Query: 233 GQTPPRPPLGPPGPPGPPGPP--------PPGQVLPPPLAGPPNRGDR-PPPPVLFPGQP 283
           G+  PR P GP GPPGP G P        P    +  P   P  RG+  PP P  FPG P
Sbjct: 756 GKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAP 815

Query: 284 FGQPPLGPLPPGPPPPVPGYGPPPG--PPPPQQGPPPPPGP-------FPPRPPGPLGPP 334
                 G       P   G G PPG   PP   GP  PPGP         P  PG  G P
Sbjct: 816 GQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFP 875

Query: 335 LTLAPPPHLPGPP-----PGAPPPAPHVNPAFFPPP---TNSGMPTSDSRGPPPTDPYGR 386
                   LPGPP     PG  PP P  +P    PP    N+G P S     P  D    
Sbjct: 876 GARG----LPGPPGSNGNPG--PPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQP 929

Query: 387 PPPYDRGDYGPPG 399
                 G  GPPG
Sbjct: 930 GEKGSPGAQGPPG 942



 Score = 89.7 bits (221), Expect = 6e-18
 Identities = 89/257 (34%), Positives = 99/257 (38%), Gaps = 48/257 (18%)

Query: 178 GQMSGEGKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQT 235
           G    +GK GPPG  G S    P G  G    P   PG   FPGP G  G P        
Sbjct: 543 GGPGSDGKPGPPGSQGESGRPGPPGPSG----PRGQPGVMGFPGPKGNDGAPGKNGERGG 598

Query: 236 PPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDR-PPPPVLFPGQP-FGQPPLGPLP 293
           P  P  GP GPPG  G   P Q  P P     ++GD  PP P    G P  G PP     
Sbjct: 599 PGGP--GPQGPPGKNGETGP-QGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGK 655

Query: 294 PGPPPPVPGYGPPPGP-------PPPQQGPP------------PPPGP-------FPPRP 327
           PG P P    G P  P        P ++GPP             PPGP        PP P
Sbjct: 656 PGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGP 715

Query: 328 PGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGP-PPTDPYGR 386
           PG  G P        +PG   G   P P  +      P   G+P  D  GP  PT P G 
Sbjct: 716 PGAAGTPGLQG----MPGERGGLGSPGPKGDKGEPGGPGADGVPGKD--GPRGPTGPIGP 769

Query: 387 P----PPYDRGDYGPPG 399
           P     P D+G+ G PG
Sbjct: 770 PGPAGQPGDKGEGGAPG 786



 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 93/278 (33%), Positives = 102/278 (36%), Gaps = 58/278 (20%)

Query: 176  QSGQMSGEGKAGPPGGSSRAA--FPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAG 233
            + G+    G AGPPGGS  A    PQG +G    PG  PG   FPG  G  GPP     G
Sbjct: 832  EKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGG-PGAAGFPGARGLPGPPGS--NG 888

Query: 234  QTPPRPPLGPPGPPGPPGPP-PPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPL 292
               P  P G PG  GPPGP    G    P ++GP  +GD   P     G P  Q P  P 
Sbjct: 889  NPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGP--KGDAGQPGE--KGSPGAQGP--PG 942

Query: 293  PPGP--------------PPPVPGYGPPPGPP--PPQQGPPPPPGPFPPR-PPGPLGPP- 334
             PGP              PP +PG    PGP     + G P   G    R PPGP G P 
Sbjct: 943  APGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPG 1002

Query: 335  -LTLAPPPHLPGPP-----------------------PGAPPPAPHVNPAFFPPPTNSGM 370
                A  P   G P                       PGAP    H  P   P P     
Sbjct: 1003 LAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGP---PGPVGPAG 1059

Query: 371  PTSDSRGPPPTDPYGRP-PPYDRGDYGPPGREMDTART 407
             + D     P  P G P P   RG  GP G   D   T
Sbjct: 1060 KSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGET 1097



 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 91/274 (33%), Positives = 108/274 (39%), Gaps = 50/274 (18%)

Query: 176 QSGQMSGEGKAGPPGGSSRAAFP-----QGGRGRGRFPG-----AVPG--GDR----FPG 219
           + G+   +G+ GP G    A  P     +G  G+   PG      +PG  G+R    F G
Sbjct: 433 EPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRG 492

Query: 220 PAGPGG-PPPPFPAGQTPPRPPLGPPGPPGPPG----PPPPGQVLPPPLAGPPNRGDRPP 274
           PAGP G P    PAG+     P GP G  G PG    P  PG    P   G P    +P 
Sbjct: 493 PAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPG 552

Query: 275 PPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPP---------------PGPPPPQQGPPPP 319
           PP    G+     P GP  P   P V G+  P               PG P PQ GPP  
Sbjct: 553 PPGS-QGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQ-GPPGK 610

Query: 320 PGPFPPR-PPGPLGP----PLTLAPPPH-LPGPPPGAPPPAPHVNPAFFPPPTNSGMP-- 371
            G   P+ PPGP GP      T  P P  L G P    PP  +  P    P  ++G P  
Sbjct: 611 NGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGA 670

Query: 372 ---TSDSRGPPPTDPYG-RPPPYDRGDYGPPGRE 401
                D+  P    P G    P  RG  GPPG E
Sbjct: 671 PGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPE 704



 Score = 84.0 bits (206), Expect = 3e-16
 Identities = 80/232 (34%), Positives = 89/232 (38%), Gaps = 36/232 (15%)

Query: 178 GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGP----AGPGGPPPPFPAG 233
           G     G+ GPPG S     P+G  G   FPG   G D  PG      GPGGP P  P G
Sbjct: 555 GSQGESGRPGPPGPSG----PRGQPGVMGFPGP-KGNDGAPGKNGERGGPGGPGPQGPPG 609

Query: 234 QTPPRPPLGPPGPPGPPGPP----PPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPL 289
           +     P GPPGP GP G      PPG   P  L G P  G  PP     PG+P      
Sbjct: 610 KNGETGPQGPPGPTGPGGDKGDTGPPG---PQGLQGLPGTGG-PPGENGKPGEP------ 659

Query: 290 GPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPG 349
           GP      P  PG G      P ++GPP   G      PG  G     A PP   G    
Sbjct: 660 GPKGDAGAPGAPG-GKGDAGAPGERGPPGLAGA-----PGLRGG----AGPPGPEGGKGA 709

Query: 350 APPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGRE 401
           A PP P   P     P   GMP        P     +  P   G  G PG++
Sbjct: 710 AGPPGP---PGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKD 758



 Score = 80.5 bits (197), Expect = 4e-15
 Identities = 65/183 (35%), Positives = 73/183 (39%), Gaps = 23/183 (12%)

Query: 184  GKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPF-PAGQTPPRPPLG 242
            G+ G PGG       +G RG    PGA PG    PGP GP GP       G++ P  P G
Sbjct: 1023 GRDGSPGG-------KGDRGENGSPGA-PGAPGHPGPPGPVGPAGKSGDRGESGPAGPAG 1074

Query: 243  PPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVL----FPGQPFGQPPLGPLPP---- 294
             PGP G  G P P      P       G+R    +     FPG P      GP       
Sbjct: 1075 APGPAGSRGAPGP----QGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAI 1130

Query: 295  GPPPPVPGYGPP-PGPPPPQQGPPPPPGPF-PPRPPGPLGPPLTLAPPPHLPGPPPGAPP 352
            G P P    GP  P  PP + G    PGP  PP P G  G   +   P H   P P  PP
Sbjct: 1131 GSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPP 1190

Query: 353  PAP 355
             AP
Sbjct: 1191 GAP 1193



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 82/283 (28%), Positives = 97/283 (34%), Gaps = 64/283 (22%)

Query: 178 GQMSGEGKAGPPGGSSRAAFP--------------QGGRGRGRFPG-----AVPGGDRFP 218
           G+    G  GPPG    A  P               G +G    PG      +PG +  P
Sbjct: 237 GRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAP 296

Query: 219 GPAGPGGPP-----PPFPA-----GQTPPRPPLGPPGPPGPPG-------PPPPGQVLPP 261
           GP GP G P     P  P      G    R   G PGPPGPPG       P   G+V P 
Sbjct: 297 GPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPA 356

Query: 262 PLAG----PPNRGDR----------PPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPP 307
              G    P  RG+           PP P    G P G+  +GP      P + G   PP
Sbjct: 357 GSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPP 416

Query: 308 GPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAP--PPHLPGPPPGAPPPAPHVNPAFFPPP 365
           GP      P    G   P   G  G P          +PG P          +P     P
Sbjct: 417 GPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPG---EP 473

Query: 366 TNSGMP-TSDSRGPP----PTDPYGRP----PPYDRGDYGPPG 399
             +G+P  +  RG P    P  P G P    P  +RG  GP G
Sbjct: 474 GANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAG 516



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 98/314 (31%), Positives = 111/314 (35%), Gaps = 95/314 (30%)

Query: 178 GQMSGEGKAGPPG------GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPP-- 229
           GQ    G  GPPG         +   PQ      +   AV G   +PGPAGP GPP P  
Sbjct: 127 GQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPG 186

Query: 230 ---------FPAGQTPPRPP-----LGPPGPPGPPGPP-PPGQVLPPPLAGPPNRGDRPP 274
                     P  Q PP  P      GPPGPPG  GP  P G+       G P     P 
Sbjct: 187 TSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPG 246

Query: 275 PPVL--------FPGQ--------------PFGQPPL---GPLP-----PGP--PPPVPG 302
           PP +        FPG                 G P L     LP     PGP  P   PG
Sbjct: 247 PPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPG 306

Query: 303 YGPPPGPP--------------PPQQGPPPPPGP--FPPRP-----PGPLGPPLTLAPPP 341
               PG P                Q GPP PPG   FP  P      GP G P +   P 
Sbjct: 307 ERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPG 366

Query: 342 HL--PGP--------PPGAPPPAPHVNPAFFPPPTNSGMPTS----DSRGPP-PTDPYGR 386
               PGP        PPG  PP  + +P        +G+P +     +RGPP P    G 
Sbjct: 367 QRGEPGPQGHAGAQGPPG--PPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGA 424

Query: 387 PPPYDRGDYGPPGR 400
           P    RG  G PG+
Sbjct: 425 PGL--RGGAGEPGK 436



 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 72/223 (32%), Positives = 80/223 (35%), Gaps = 56/223 (25%)

Query: 218 PGPAGPGGP-----PPPFPAGQTPP--RPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRG 270
           P P  P G      P P  A   PP  + P GP G PGPPG   PG+   P + G P   
Sbjct: 75  PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPG--IPGRNGDPGIPGQPGSP 132

Query: 271 DRPPPPVLFPGQPFGQPPLGPL-----------------------PPGPPPPVPGYGPPP 307
             P PP +    P G     P                        PPGPP P PG    P
Sbjct: 133 GSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGP-PGTSGHP 191

Query: 308 GPP--PPQQGPPPPPGPF----PPRPPGPLGP--PLTLAPPPHLPGPP--PGAPPPAPHV 357
           G P  P  QGPP  PG      PP PPG +GP  P         PG P   G P P    
Sbjct: 192 GSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIK 251

Query: 358 NPAFFPP-PTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPG 399
            PA  P  P   G    D R              ++G+ G PG
Sbjct: 252 GPAGIPGFPGMKGHRGFDGRNG------------EKGETGAPG 282



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 61/147 (41%), Positives = 66/147 (44%), Gaps = 28/147 (19%)

Query: 176  QSGQMSGEGKAGP-----PGGSSRAAFPQGGRG-RG----RFPGAVPGGDRFPGPAGPGG 225
            +SG     G AGP     P GS  A  PQG RG +G    R    + G   FPG   PG 
Sbjct: 1060 KSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPG--NPGA 1117

Query: 226  PPPPFPAGQTPPRPPLGPPGPPGPPGP--PP--------PGQVLPPPLAGPPNRGDRPPP 275
            P  P PAGQ       GP GP GP GP  PP        PG + PP   G  NRG+R   
Sbjct: 1118 PGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRG--NRGERGSE 1175

Query: 276  PVLFPGQPFGQPPLGPLPPGPPPPVPG 302
                PG P GQP   P PPG P P  G
Sbjct: 1176 G--SPGHP-GQPG-PPGPPGAPGPCCG 1198



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 22/58 (37%), Positives = 25/58 (43%), Gaps = 8/58 (13%)

Query: 176  QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAG 233
            + G     G  GPPG       P+G RG     G+ PG    PGP GP G P P   G
Sbjct: 1150 KDGTSGHPGPIGPPG-------PRGNRGERGSEGS-PGHPGQPGPPGPPGAPGPCCGG 1199


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score =  103 bits (256), Expect = 5e-22
 Identities = 89/242 (36%), Positives = 103/242 (42%), Gaps = 39/242 (16%)

Query: 226 PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAG---PPNRGDRPPPPVLFPGQ 282
           PPP  P  Q PP  P  PP P  PP  PPP  V+PP L     PP      PPPV+ P  
Sbjct: 517 PPPFVPYSQMPPPLPTMPP-PVLPPSLPPP--VMPPALPATVPPPGM----PPPVMPPSL 569

Query: 283 PFGQPP---------LGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGP 333
           P   PP          GP P  PPP +   GPPP  PPP      PP      P  PL P
Sbjct: 570 PTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPP------PVMPL-P 622

Query: 334 PLTLAPPPHLPG-PPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDR 392
           PL+ A PP  PG PPPG P   P    A   PP +S   +  S+ P    P   P P   
Sbjct: 623 PLSSATPP--PGIPPPGVPQGIPPQLTAAPVPPASS---SQSSQVPEKPRPALLPTPVSF 677

Query: 393 GDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSAI--SRAVSDASAGDYGSAIETLVT 450
           G   P      T   PL  A   E +N    +S SA+  S   SD   G+  +A    +T
Sbjct: 678 GSAPP-----TTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPIT 732

Query: 451 AI 452
           A+
Sbjct: 733 AV 734



 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 59/192 (30%), Positives = 70/192 (36%), Gaps = 16/192 (8%)

Query: 226 PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVL----PPPLAGPPNRGDRPPPPVLFPG 281
           PPPP P     P    G   PP PP PPPPG  L                R  PP L P 
Sbjct: 82  PPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPM 141

Query: 282 QPFGQPPLGPLPPGP-PPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLT---L 337
           +    P   P+PPG   PP   Y PPP PPP    P       PP  P P   P +   L
Sbjct: 142 ELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYL 201

Query: 338 APPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGP 397
           AP P        +     H        P++   P+  S+G   +     PPP       P
Sbjct: 202 APTPSYSSSSSSSQSYLSHSQSYL---PSSQASPSRPSQGHSKSQLLAPPPP-----SAP 253

Query: 398 PGREMDTARTPL 409
           PG +    + PL
Sbjct: 254 PGNKTTVQQEPL 265



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 85/300 (28%), Positives = 115/300 (38%), Gaps = 57/300 (19%)

Query: 267  PNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPR 326
            P   D  PP          +P + P PPG   P P  G PPG       PP        R
Sbjct: 1483 PQMADHLPPQESRLQNTSSRPGMYP-PPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTR 1541

Query: 327  PPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGM-PTSDSRG-------- 377
            PP P+ PP    PPP LP PPP   P    V    +   +  G+  T+D +G        
Sbjct: 1542 PPVPIPPP---PPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSE 1598

Query: 378  --PPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSAISRAVSD 435
                P+ P   PPP       PPG  +     P+S+                 + + V  
Sbjct: 1599 TAAIPSAPVLPPPPV-HSSIPPPG-PVPMGMPPMSK--------------PPPVQQTV-- 1640

Query: 436  ASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGIESKSYGSGSRRERSR 495
                DYG   +     IS  K  ++   +R  +    L +     E++  G   R +R R
Sbjct: 1641 ----DYGHGRD-----ISTNKVEQIPYGERITLRPDPLPE-RSTFETEHAGQRDRYDRER 1690

Query: 496  ERDHSRSREKSRRHKSRSRDRHDDYYRERSRERERHRDRDRDR---DRERDR-EREYRHR 551
            +R+    R+      S     H D+     R+RE HRDRDRDR   D +RDR +RE R R
Sbjct: 1691 DREPYFDRQ------SNVIADHRDF----KRDRETHRDRDRDRGVIDYDRDRFDRERRPR 1740



 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 65/207 (31%), Positives = 74/207 (35%), Gaps = 33/207 (15%)

Query: 247 PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPG-----------------------QP 283
           P PP PPPP   LP    GP       P      G                       Q 
Sbjct: 15  PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74

Query: 284 FGQPPLGPLPPGPPPPV---PGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPP 340
             QP   P PP PPPPV    GYG    PPPP    PPPPGP              L   
Sbjct: 75  VLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPM---PPPPGPALSYQKQQQYKHQML--- 128

Query: 341 PHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGR 400
            H    PPG  P      P   P P  S MP S S  PPP  P    PP     Y PP  
Sbjct: 129 HHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPA- 187

Query: 401 EMDTARTPLSEAEFEEIMNRNRAISSS 427
           +   +++P S++      + + + SSS
Sbjct: 188 QPSPSQSPPSQSYLAPTPSYSSSSSSS 214



 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 45/127 (35%), Positives = 48/127 (37%), Gaps = 17/127 (13%)

Query: 223 PGGPPPPFPAGQTPPRPP-----LGPPGPPGPPG----PPPPGQVLPPPLAGPPNRGDRP 273
           PG PP    AG  P  PP      GPP    PP      PPP   LPP  +        P
Sbjct: 576 PGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSA------TP 629

Query: 274 PPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGP 333
           PP +  PG P G PP   L   P PP         P  P+    P P  F   PP    P
Sbjct: 630 PPGIPPPGVPQGIPP--QLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHP 687

Query: 334 PLTLAPP 340
           PL  A P
Sbjct: 688 PLQSAGP 694



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 47/156 (30%), Positives = 52/156 (33%), Gaps = 46/156 (29%)

Query: 229  PFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAG-PPNRGDRPPPPVLFPGQPFGQP 287
            P  A   PP+          P   PPPG   PPP  G PP    RP  P      P  +P
Sbjct: 1483 PQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRP 1542

Query: 288  PLGPLPPGPPPPVPGYGPPPGPPPPQ-----------------------QG--------- 315
            P+   PP PPPP+P   PPP    PQ                       QG         
Sbjct: 1543 PVPIPPPPPPPPLP---PPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSET 1599

Query: 316  ----------PPPPPGPFPPRPPGPLGPPLTLAPPP 341
                      PPP     PP  P P+G P    PPP
Sbjct: 1600 AAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPP 1635



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 52/177 (29%), Positives = 62/177 (35%), Gaps = 36/177 (20%)

Query: 161  KQFLSQFEMQSRKTTQSGQMSGEGKAG---PPGGSSRAAFPQGGRGRGRFPGAVPGGDRF 217
            K F S+ +M      Q  ++          PP GS R   P G     + PG++      
Sbjct: 1477 KDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMG-----KPPGSI------ 1525

Query: 218  PGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPV 277
                 P  PP       T P  P+ PP PP P  PPPP  + P   A    R D      
Sbjct: 1526 ---VRPSAPPARSSVPVTRPPVPIPPPPPPPPL-PPPPPVIKPQTSAVEQERWDEDSFYG 1581

Query: 278  L------------FPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPP---PQQGPPPP 319
            L            F  +    P     P  PPPPV    PPPGP P   P    PPP
Sbjct: 1582 LWDTNDEQGLNSEFKSETAAIP---SAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPP 1635



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 40/134 (29%), Positives = 44/134 (32%), Gaps = 41/134 (30%)

Query: 208  PGAVPGGDRFPGPAGPGGPPPPFPAGQTPP--------RPPLG-PPGPPGPPGPPPPGQV 258
            PG  P    +  P   G PP        PP        RPP+  PP PP PP PPPP  +
Sbjct: 1503 PGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVI 1562

Query: 259  LPPPLAGPPNRGDR--------------------------------PPPPVLFPGQPFGQ 286
             P   A    R D                                 PPPPV     P G 
Sbjct: 1563 KPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGP 1622

Query: 287  PPLGPLPPGPPPPV 300
             P+G  P   PPPV
Sbjct: 1623 VPMGMPPMSKPPPV 1636



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 68/295 (23%), Positives = 76/295 (25%), Gaps = 139/295 (47%)

Query: 218 PGPAGPGG-------PPPPFPAGQTPPRPPL------------------GPPG------- 245
           P P  PGG       PPPP P    PP P L                  GPPG       
Sbjct: 88  PPPVMPGGGYGDWQPPPPPMPP---PPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELE 144

Query: 246 -----PPGPPGP--PPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQ--PP----LGPL 292
                PP PPG   PP    +PPP   P         P L P QP     PP    L P 
Sbjct: 145 SPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPT 204

Query: 293 PP------------------------GPPPPVPGYG-------PPPGPPP---------- 311
           P                          P  P  G+        PPP  PP          
Sbjct: 205 PSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEP 264

Query: 312 ------------PQQGPPPPPGPFPPRP-------------------------------- 327
                        Q  P P P    P+                                 
Sbjct: 265 LESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAK 324

Query: 328 --PGPLGPPLTLAPPPHLPGPP----PGAPPPAPHVNPAFFPPPTNSGMPTSDSR 376
             P P+   +T+     +P  P    P  PPP   V P   P    S  P  D+R
Sbjct: 325 DTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDAR 379



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 4/65 (6%)

Query: 329 GPLGPPLTLAPPPHLPGPPPGAPPPA--PHVNPAFFPPPTNSGMPTSDSRGP--PPTDPY 384
           G +  P    P   +P P P  PPP   P + P   PP   + +P      P  PP+ P 
Sbjct: 512 GNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPT 571

Query: 385 GRPPP 389
             PPP
Sbjct: 572 SVPPP 576



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 60/272 (22%), Positives = 81/272 (29%), Gaps = 61/272 (22%)

Query: 218 PGPAGPGGPPPPFPAGQTPP-------------RPPLGPPGPPGPPGPPPPGQVLPPPLA 264
           P P  P G PP   A   PP             RP L P   P   G  PP    PP  +
Sbjct: 634 PPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPT--PVSFGSAPPTTYHPPLQS 691

Query: 265 GPPNRGDRPPPPVLFPGQPFGQ------------PPLGPLPPGPPPPVPGYGPPPGPPPP 312
             P+       P+     P+               P  P+      PV   G  P PP  
Sbjct: 692 AGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRS 751

Query: 313 Q--QGPPPPPGPFP------------PRPPGP-LGPPLTLAPPPHLPGPP---------- 347
              + P  P    P            PRP GP         P P   G P          
Sbjct: 752 SYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGM 811

Query: 348 -PGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTAR 406
            P  P    ++ P+    P  SG      +GP P   +G+           P   +   +
Sbjct: 812 IPRGPASQFYITPSTSLSPRQSG---PQWKGPKPA--FGQQHQQQPKSQAEP---LSGNK 863

Query: 407 TPLSEAEFEEIMNRNRAISSSAISRAVSDASA 438
            PL++    +  N     ++ +I+  V D  A
Sbjct: 864 EPLADTSSNQQKNFKMQSAAFSIAADVKDVKA 895



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 16/40 (40%), Positives = 19/40 (47%), Gaps = 2/40 (5%)

Query: 220  PAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVL 259
            P+ P  PPPP  +   PP P   P G P    PPP  Q +
Sbjct: 1603 PSAPVLPPPPVHSSIPPPGPV--PMGMPPMSKPPPVQQTV 1640



 Score = 29.6 bits (65), Expect = 7.5
 Identities = 18/58 (31%), Positives = 23/58 (39%), Gaps = 1/58 (1%)

Query: 217  FPGPAGPGGPPPPFPAGQTP-PRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRP 273
            + GP+  GG    +P  + P P P L    PP P     P       +  PP R  RP
Sbjct: 1775 YEGPSMFGGERRTYPEERMPLPAPSLSHQPPPAPRVEKKPESKNVDDILKPPGRESRP 1832



 Score = 29.3 bits (64), Expect = 9.8
 Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 1/49 (2%)

Query: 497  RDHSRSREKSRRHKSRSRDRH-DDYYRERSRERERHRDRDRDRDRERDR 544
            R+   S   SR H    R    DD+ R++  + + +R+ +RD DR+ DR
Sbjct: 1244 REDRFSAPPSRSHDGDRRGPWWDDWERDQDMDEDYNREMERDMDRDVDR 1292


>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score =  102 bits (255), Expect = 7e-22
 Identities = 105/297 (35%), Positives = 120/297 (40%), Gaps = 77/297 (25%)

Query: 176 QSGQMSGEGKAGPPG--------GSSRAAF--PQGGRGRGRFPGAV-PGGDRFP-GPAGP 223
           Q G   G+G+ G PG        G  +  F  P+G RG G  PGA+ P G++ P G  G 
Sbjct: 326 QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGI 385

Query: 224 GGPP--PPFPAGQTPPRPP--------------LGPPGPPGPPGPP-------------- 253
           GGPP  P  P    P  PP              +GP GPPGP G P              
Sbjct: 386 GGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGE 445

Query: 254 --PPG-QVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG-PLPPGP-----PPPVPGYG 304
             PPG + LP P+      G +  P +  PG P    P G P  PG      PP +PG G
Sbjct: 446 VGPPGMRGLPGPIGPKGEAGQKGVPGL--PGVPGLLGPKGEPGIPGDQGLQGPPGIPGIG 503

Query: 305 PPPGP--PPPQQGPPPPPG-PFPPRPP-----------GPLGPPLTLAP--PPHLPGPP- 347
            P GP  PP   GP   PG P PP  P           GP G P  L P   P LPGPP 
Sbjct: 504 GPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPG 563

Query: 348 PGAPPPAPHVNPAFFPPPTNSGMPTS--DSRGPPPTDPYGRPPPYDRGDYGPPGREM 402
           P  PP  P V P   PPP    +P       G  P   YG      +G  G P  EM
Sbjct: 564 PPGPPGPPAVMPP-TPPPQGEYLPDMGLGIDGVKPPHAYGA----KKGKNGGPAYEM 615



 Score = 95.9 bits (237), Expect = 9e-20
 Identities = 94/247 (38%), Positives = 105/247 (42%), Gaps = 38/247 (15%)

Query: 178 GQMSGEGKAGPPG--GSSRAAFPQGGRGRGRFPGAV-----PGGDRFPGPAGPGGPPPPF 230
           GQ   +G  GP G  G      P+G +G G  PGA      PG    PGP G  G   P 
Sbjct: 217 GQPGPKGDRGPKGLPGPQGLRGPKGDKGFG-MPGAPGVKGPPGMHGPPGPVGLPGVGKPG 275

Query: 231 PAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPN-RGDRPPPPVLFPGQP-----F 284
             G   P+ PLG PG PG PGP  P  V  P + GPP   G   P     PGQP      
Sbjct: 276 VTGFPGPQGPLGKPGAPGEPGPQGPIGV--PGVQGPPGIPGIGKPGQDGIPGQPGFPGGK 333

Query: 285 GQPPLGPLPPGPPPPVPGYGPPPGP-PPPQQGPPPPPGPFPPR-PPGPLGPPLTLAPP-- 340
           G+  L  LP   PP +PG G P  P P   +G    PG   PR   GP+G P    PP  
Sbjct: 334 GEQGLPGLP--GPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGE 391

Query: 341 PHLPG-PPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP-------PPYDR 392
           P LPG P P  PP A       FP P   G      +GPP   P G P        P   
Sbjct: 392 PGLPGIPGPMGPPGA-----IGFPGPKGEG-GIVGPQGPP--GPKGEPGLQGFPGKPGFL 443

Query: 393 GDYGPPG 399
           G+ GPPG
Sbjct: 444 GEVGPPG 450



 Score = 86.7 bits (213), Expect = 5e-17
 Identities = 80/240 (33%), Positives = 98/240 (40%), Gaps = 37/240 (15%)

Query: 184 GKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP-------PPFPAGQ 234
           G+ GPPG  G      P+G  G+   PG +PG     GP G  G P       PP   G 
Sbjct: 444 GEVGPPGMRGLPGPIGPKGEAGQKGVPG-LPGVPGLLGPKGEPGIPGDQGLQGPPGIPGI 502

Query: 235 TPPRPPLGPPGPPGPPGPPP-PGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLP 293
             P  P+GPPG PGP G P  PG    P +  P   G   PP       P GQP L P P
Sbjct: 503 GGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGL-PGP 561

Query: 294 PGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPP 353
           PGPP P       PGPP      PPP G + P     +G  +    PPH  G   G    
Sbjct: 562 PGPPGP-------PGPPAVMPPTPPPQGEYLP----DMGLGIDGVKPPHAYGAKKGKNGG 610

Query: 354 APHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAE 413
             +  PAF          T++   P P  P G P  +++  Y   GR+    +T +   E
Sbjct: 611 PAYEMPAF----------TAELTAPFP--PVGAPVKFNKLLYN--GRQNYNPQTGIFTCE 656



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 79/232 (34%), Positives = 93/232 (40%), Gaps = 44/232 (18%)

Query: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFP-GPAGPGGPPPPFPAGQTPPRPPLGPPGP 246
           P     + A P+ G+     P A   G++ P G  GP GPP P      P  P  G PG 
Sbjct: 95  PAPRMGKEAVPKKGK---EIPLASLRGEQGPRGEPGPRGPPGP------PGLPGHGIPGI 145

Query: 247 PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQ--PFGQP----PLG-PLPPGPPPP 299
            G PGP     V  P + G P +    P  +  PG     GQ     P+G P P GPP P
Sbjct: 146 KGKPGPQGYPGVGKPGMPGMPGK----PGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGP 201

Query: 300 --VPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPP-----HLPGPPPGAPP 352
             +PG G P GP     G P  PGP   R P  L  P  L  P       +PG P    P
Sbjct: 202 HGLPGIGKPGGP-----GLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGP 256

Query: 353 PAPHVNPAFFPPPTNSGMPTSDSRG----PPPTDPYGRP-PPYDRGDYGPPG 399
           P  H       PP   G+P     G    P P  P G+P  P + G  GP G
Sbjct: 257 PGMH------GPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIG 302



 Score = 32.7 bits (73), Expect = 0.89
 Identities = 39/121 (32%), Positives = 45/121 (37%), Gaps = 14/121 (11%)

Query: 281 GQPFGQPPLGP-LPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAP 339
           G  +G  PL P +PP  PP +P Y       P  Q  P  P        G   P L    
Sbjct: 28  GAYYGIKPLPPQIPPQMPPQIPQY------QPLGQQVPHMPLAKDGLAMGKEMPHLQYGK 81

Query: 340 P-PHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPP 398
             PHLP        PAP +      P     +P +  RG     P G P P  RG  GPP
Sbjct: 82  EYPHLPQYMKEI-QPAPRMGKEAV-PKKGKEIPLASLRG--EQGPRGEPGP--RGPPGPP 135

Query: 399 G 399
           G
Sbjct: 136 G 136


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score =  102 bits (255), Expect = 7e-22
 Identities = 105/297 (35%), Positives = 120/297 (40%), Gaps = 77/297 (25%)

Query: 176 QSGQMSGEGKAGPPG--------GSSRAAF--PQGGRGRGRFPGAV-PGGDRFP-GPAGP 223
           Q G   G+G+ G PG        G  +  F  P+G RG G  PGA+ P G++ P G  G 
Sbjct: 326 QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGI 385

Query: 224 GGPP--PPFPAGQTPPRPP--------------LGPPGPPGPPGPP-------------- 253
           GGPP  P  P    P  PP              +GP GPPGP G P              
Sbjct: 386 GGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGE 445

Query: 254 --PPG-QVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG-PLPPGP-----PPPVPGYG 304
             PPG + LP P+      G +  P +  PG P    P G P  PG      PP +PG G
Sbjct: 446 VGPPGMRGLPGPIGPKGEAGQKGVPGL--PGVPGLLGPKGEPGIPGDQGLQGPPGIPGIG 503

Query: 305 PPPGP--PPPQQGPPPPPG-PFPPRPP-----------GPLGPPLTLAP--PPHLPGPP- 347
            P GP  PP   GP   PG P PP  P           GP G P  L P   P LPGPP 
Sbjct: 504 GPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPG 563

Query: 348 PGAPPPAPHVNPAFFPPPTNSGMPTS--DSRGPPPTDPYGRPPPYDRGDYGPPGREM 402
           P  PP  P V P   PPP    +P       G  P   YG      +G  G P  EM
Sbjct: 564 PPGPPGPPAVMPP-TPPPQGEYLPDMGLGIDGVKPPHAYGA----KKGKNGGPAYEM 615



 Score = 95.9 bits (237), Expect = 9e-20
 Identities = 94/247 (38%), Positives = 105/247 (42%), Gaps = 38/247 (15%)

Query: 178 GQMSGEGKAGPPG--GSSRAAFPQGGRGRGRFPGAV-----PGGDRFPGPAGPGGPPPPF 230
           GQ   +G  GP G  G      P+G +G G  PGA      PG    PGP G  G   P 
Sbjct: 217 GQPGPKGDRGPKGLPGPQGLRGPKGDKGFG-MPGAPGVKGPPGMHGPPGPVGLPGVGKPG 275

Query: 231 PAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPN-RGDRPPPPVLFPGQP-----F 284
             G   P+ PLG PG PG PGP  P  V  P + GPP   G   P     PGQP      
Sbjct: 276 VTGFPGPQGPLGKPGAPGEPGPQGPIGV--PGVQGPPGIPGIGKPGQDGIPGQPGFPGGK 333

Query: 285 GQPPLGPLPPGPPPPVPGYGPPPGP-PPPQQGPPPPPGPFPPR-PPGPLGPPLTLAPP-- 340
           G+  L  LP   PP +PG G P  P P   +G    PG   PR   GP+G P    PP  
Sbjct: 334 GEQGLPGLP--GPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGE 391

Query: 341 PHLPG-PPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP-------PPYDR 392
           P LPG P P  PP A       FP P   G      +GPP   P G P        P   
Sbjct: 392 PGLPGIPGPMGPPGA-----IGFPGPKGEG-GIVGPQGPP--GPKGEPGLQGFPGKPGFL 443

Query: 393 GDYGPPG 399
           G+ GPPG
Sbjct: 444 GEVGPPG 450



 Score = 86.7 bits (213), Expect = 5e-17
 Identities = 80/240 (33%), Positives = 98/240 (40%), Gaps = 37/240 (15%)

Query: 184 GKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP-------PPFPAGQ 234
           G+ GPPG  G      P+G  G+   PG +PG     GP G  G P       PP   G 
Sbjct: 444 GEVGPPGMRGLPGPIGPKGEAGQKGVPG-LPGVPGLLGPKGEPGIPGDQGLQGPPGIPGI 502

Query: 235 TPPRPPLGPPGPPGPPGPPP-PGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLP 293
             P  P+GPPG PGP G P  PG    P +  P   G   PP       P GQP L P P
Sbjct: 503 GGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGL-PGP 561

Query: 294 PGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPP 353
           PGPP P       PGPP      PPP G + P     +G  +    PPH  G   G    
Sbjct: 562 PGPPGP-------PGPPAVMPPTPPPQGEYLP----DMGLGIDGVKPPHAYGAKKGKNGG 610

Query: 354 APHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAE 413
             +  PAF          T++   P P  P G P  +++  Y   GR+    +T +   E
Sbjct: 611 PAYEMPAF----------TAELTAPFP--PVGAPVKFNKLLYN--GRQNYNPQTGIFTCE 656



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 79/232 (34%), Positives = 93/232 (40%), Gaps = 44/232 (18%)

Query: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFP-GPAGPGGPPPPFPAGQTPPRPPLGPPGP 246
           P     + A P+ G+     P A   G++ P G  GP GPP P      P  P  G PG 
Sbjct: 95  PAPRMGKEAVPKKGK---EIPLASLRGEQGPRGEPGPRGPPGP------PGLPGHGIPGI 145

Query: 247 PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQ--PFGQP----PLG-PLPPGPPPP 299
            G PGP     V  P + G P +    P  +  PG     GQ     P+G P P GPP P
Sbjct: 146 KGKPGPQGYPGVGKPGMPGMPGK----PGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGP 201

Query: 300 --VPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPP-----HLPGPPPGAPP 352
             +PG G P GP     G P  PGP   R P  L  P  L  P       +PG P    P
Sbjct: 202 HGLPGIGKPGGP-----GLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGP 256

Query: 353 PAPHVNPAFFPPPTNSGMPTSDSRG----PPPTDPYGRP-PPYDRGDYGPPG 399
           P  H       PP   G+P     G    P P  P G+P  P + G  GP G
Sbjct: 257 PGMH------GPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIG 302



 Score = 32.7 bits (73), Expect = 0.89
 Identities = 39/121 (32%), Positives = 45/121 (37%), Gaps = 14/121 (11%)

Query: 281 GQPFGQPPLGP-LPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAP 339
           G  +G  PL P +PP  PP +P Y       P  Q  P  P        G   P L    
Sbjct: 28  GAYYGIKPLPPQIPPQMPPQIPQY------QPLGQQVPHMPLAKDGLAMGKEMPHLQYGK 81

Query: 340 P-PHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPP 398
             PHLP        PAP +      P     +P +  RG     P G P P  RG  GPP
Sbjct: 82  EYPHLPQYMKEI-QPAPRMGKEAV-PKKGKEIPLASLRG--EQGPRGEPGP--RGPPGPP 135

Query: 399 G 399
           G
Sbjct: 136 G 136


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score =  102 bits (254), Expect = 9e-22
 Identities = 91/271 (33%), Positives = 98/271 (36%), Gaps = 60/271 (22%)

Query: 180 MSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRP 239
           M G G  GP GG      P         P    G    P    P GPPPP+     PP P
Sbjct: 382 MHGGGPGGPGGGPHSFPHP--------LPSLTGGHGGHPMQHNPNGPPPPW---MQPPPP 430

Query: 240 PLGP-PGPPGPPGPPPPGQVLPPPLAG--------------PPNRGDRPPPPVLFPGQPF 284
           P+   P PPG  GPPP  Q L     G              PP  G  PPPP    GQP 
Sbjct: 431 PMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQP- 489

Query: 285 GQPPLGPLPPG-------PPPPVPGYGPPPGPPPPQQ------------GPPPP------ 319
             PP GPLPP        PPPP P        P P Q            G  PP      
Sbjct: 490 PPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQA 549

Query: 320 PGPFPPRPPGPLGPPLTLAPPPHLPGP-PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGP 378
                P  P   G P  +  PP +  P PPGAPPP P       PPP ++GM  +    P
Sbjct: 550 AAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPP------PPPGSAGMMYAPPPPP 603

Query: 379 -PPTDPYGRPPPYDRGDYGPPGREMDTARTP 408
            PP DP         G  G P   M  A  P
Sbjct: 604 PPPMDPSNFVTMMGMGVAGMPPFGMPPAPPP 634



 Score = 92.4 bits (228), Expect = 9e-19
 Identities = 72/213 (33%), Positives = 81/213 (38%), Gaps = 48/213 (22%)

Query: 188 PPGGSSRAAFPQGGRG---RGRFPGAVPGGDRF-----------PGPAGPGGPPPPFPAG 233
           PP   ++   P G  G     ++ G+ P G              P P G   PPPP P+G
Sbjct: 428 PPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSG 487

Query: 234 QTPPRPPLGPPGP-------PGPPGPPPPGQVLPPPLAGPPNR---------GDRPP--- 274
           Q PP PP GP  P       P PP PP        PL    N          G  PP   
Sbjct: 488 QPPP-PPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQ 546

Query: 275 ---PPVLFPGQPF--GQPPLGPLPPGPPPPVPGYGPPPGPPPPQQG-------PPPPPGP 322
                   PG P   G P + PLPPG  PP+P   PPP PPPP          PPPPP P
Sbjct: 547 QQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPP 606

Query: 323 FPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAP 355
             P     +        PP   G PP  PPP P
Sbjct: 607 MDPSNFVTMMGMGVAGMPPF--GMPPAPPPPPP 637



 Score = 82.8 bits (203), Expect = 7e-16
 Identities = 64/188 (34%), Positives = 73/188 (38%), Gaps = 23/188 (12%)

Query: 224 GGPPPPFPAGQT--PPRPPLGP-PGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFP 280
           G  P P   G T  P   PL   P P  P   PPP  ++    + PP     P     + 
Sbjct: 321 GEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH 380

Query: 281 GQPFGQPP-LGPLPPGPPPPVP----GYGPPP------GPPPPQQGPPPPPGPFPPRPPG 329
           G   G P   G  P   P P+P    G+G  P      GPPPP   PPPPP    P PPG
Sbjct: 381 GMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPG 440

Query: 330 PLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389
             GPP       +L   P G+     H      PPP    MP      PPP  P G+PPP
Sbjct: 441 HHGPP---PMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMP------PPPPPPSGQPPP 491

Query: 390 YDRGDYGP 397
              G   P
Sbjct: 492 PPSGPLPP 499



 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 74/226 (32%), Positives = 88/226 (38%), Gaps = 29/226 (12%)

Query: 193 SRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPL-----GPPGPP 247
           SR  +   G    R    + GG    GP GPGG P  FP     P P L     G P   
Sbjct: 364 SRPPWMNSGPSESRPYHGMHGG----GPGGPGGGPHSFPH----PLPSLTGGHGGHPMQH 415

Query: 248 GPPGPPPPGQVLPPPLAGPPNRGDRPP----PPVLFPGQPFGQPPLGPLPPGPPPPVPGY 303
            P GPPPP    PPP   P N+G  PP    PP +   Q  G  P+G    G      G 
Sbjct: 416 NPNGPPPPWMQPPPP---PMNQGPHPPGHHGPPPM--DQYLGSTPVGS---GVYRLHQGK 467

Query: 304 GPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFP 363
           G  P PPP    PPPPP P    PP P GP   L P       PP  PPP+  +  +   
Sbjct: 468 GMMP-PPPMGMMPPPPPPPSGQPPPPPSGP---LPPWQQQQQQPPPPPPPSSSMASSTPL 523

Query: 364 PPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPL 409
           P   +   T+ S G     P+ +         G P  + +    PL
Sbjct: 524 PWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPL 569



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 45/155 (29%), Positives = 57/155 (36%), Gaps = 24/155 (15%)

Query: 270 GDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPG 329
           G+ P P  +  G   G P   PL   P P  P   PPP         P        RPP 
Sbjct: 321 GEAPVPASV--GSTSG-PATTPLASAPRPAAPANNPPP---------PSLMSTTQSRPPW 368

Query: 330 PLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPT--NSGMPTSDS-RGPPPTDPYGR 386
               P    P   + G  PG P   PH  P   P  T  + G P   +  GPPP  P+ +
Sbjct: 369 MNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPP--PWMQ 426

Query: 387 PPP-------YDRGDYGPPGREMDTARTPLSEAEF 414
           PPP       +  G +GPP  +     TP+    +
Sbjct: 427 PPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVY 461


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score =  101 bits (252), Expect = 2e-21
 Identities = 73/207 (35%), Positives = 80/207 (38%), Gaps = 25/207 (12%)

Query: 208 PGAVPGGDRFPGP-AGPGGPPPPFPAGQTPPRPPLGPPGPPGPPG-PPPPGQVLPPPLAG 265
           P   P     P P A P    PP     +PP  PL  P P  PP    PP Q  P P A 
Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639

Query: 266 PPNRGDRPPPP-------VLFPGQPFGQPPLGPL-----PPGPPPPVPGYGPPPGPP--- 310
           PP      P P       V     PF  PP  P+     PP  PP  P   PP   P   
Sbjct: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 699

Query: 311 --PPQQGPPPPPGPFPPRP---PGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPP 365
             PP Q PP PP   P  P   P P  PP   APP  +P  PP +PP +P   P    PP
Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759

Query: 366 TNSGMPTSDSRGPP---PTDPYGRPPP 389
             +  P      PP   P  P  +PPP
Sbjct: 760 LLAAPPLQVPPSPPASLPMSPLAKPPP 786



 Score =  100 bits (249), Expect = 3e-21
 Identities = 78/214 (36%), Positives = 84/214 (39%), Gaps = 34/214 (15%)

Query: 227 PPPFPAGQTPPRPPLGPPGPPG--PPG--PP----PPGQVLPPPLAGPPNRGDRPPPPVL 278
           PPP P  Q P  PP  PP  P   PP   PP    PP QV P P A PP      PPP  
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726

Query: 279 FPGQPFGQPPLG--PLPPGPPPPVPGYGPPPGPPP-----PQQGPPPPPGPFPPRP---P 328
            P  P   PPL   P PP  PP  P   PPP  PP     P Q PP PP   P  P   P
Sbjct: 727 PP--PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784

Query: 329 GPLGPPLTLAPP-PHLPGPPPGAPPPAPH-------VNPAFFPPPTNSGMPTSDSRGPPP 380
            P  PP    PP   LP PP   P  AP        ++P   PPP    +  +     PP
Sbjct: 785 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 844

Query: 381 TDPYG------RPPPYDRGDYGPPGREMDTARTP 408
           + P        R PP    D    G  +  A  P
Sbjct: 845 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 878



 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 76/235 (32%), Positives = 92/235 (39%), Gaps = 29/235 (12%)

Query: 208 PGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPP 267
           P A P     P  A P    PP P    P  P   PP    PP   PP QV P P A PP
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPP 746

Query: 268 NRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVP----GYGPPPGPP----PPQQGPPPP 319
                 PPP + P      PPL  +PP PP  +P       PP  PP    PP Q  P P
Sbjct: 747 MSPSATPPPRVPP--LLAAPPL-QVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSP 803

Query: 320 PGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPP 379
           P  FP + P      L ++P   L  PPP APP      P    PP+    PT  +   P
Sbjct: 804 PASFPGQAPFSPSASLPMSP---LATPPPQAPPVL--AAPLLQVPPSPPASPTLQAPRRP 858

Query: 380 PTDPYGRPPPYDRGDYGP-------PGREMDTARTPLSEAEFEEIMNRNRAISSS 427
           PT      P  D    GP       PG     +R+P S     ++   + + +S+
Sbjct: 859 PT------PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 907



 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 70/220 (31%), Positives = 79/220 (35%), Gaps = 50/220 (22%)

Query: 220 PAGPGGPPPP-------FPAGQTPPRPPLGPP-GPPGPPGPPPPG----QVLPPPLAGPP 267
           P  P   PPP        P  Q PP PP  PP  P   P P  P      +L  P + PP
Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669

Query: 268 NRGDRPP--PPVLFPGQPFGQPP-------------LGPLPPGPPPPVPGYGPPPGPPPP 312
           +   + P  PP   P  P   PP             + P PP  PP  P   PPP  PPP
Sbjct: 670 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729

Query: 313 QQGPP------PPPGP--FPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPP 364
              PP      PP  P   P   P P  PPL  APP  +P  PP + P +P   P    P
Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAP 789

Query: 365 PTNSGMPTSDSRGPP---------------PTDPYGRPPP 389
           P  +  P      PP               P  P   PPP
Sbjct: 790 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 80/259 (30%), Positives = 88/259 (33%), Gaps = 39/259 (15%)

Query: 186 AGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPP-------FPAGQTPPR 238
           A PP   S     Q        P  VP       P  P   PPP        P  Q PP 
Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPS 740

Query: 239 PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLP----- 293
           PP  PP  P    PP     +PP LA PP +   P PP   P  P  +PP    P     
Sbjct: 741 PPASPPMSPSATPPPR----VPPLLAAPPLQVP-PSPPASLPMSPLAKPPPQAPPALATP 795

Query: 294 -----PGPPPPVPGYGP---------PPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAP 339
                P PP   PG  P          P   PP Q PP    P    PP P   P   AP
Sbjct: 796 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 855

Query: 340 -PPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPP----PTDPYGRPPPYDRGD 394
             P  PGP      P   +  A  PPP  S  P+S   GP      +     P      D
Sbjct: 856 RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD 915

Query: 395 YGPPGREMDTARTPLSEAE 413
            GP G     A +P  +AE
Sbjct: 916 SGPEG---GAAASPPPDAE 931



 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 75/229 (32%), Positives = 84/229 (36%), Gaps = 20/229 (8%)

Query: 186 AGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPP-------FPAGQTPPR 238
           A PP   S    PQ        P  VP       P  P   PPP        P  Q PP 
Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPS 771

Query: 239 PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQ-PFGQPPLGPLPPGPP 297
           PP   P    P   PPP    PP LA PP +   P PP  FPGQ PF   P   LP  P 
Sbjct: 772 PPASLP--MSPLAKPPPQA--PPALATPPLQA-LPSPPASFPGQAPFS--PSASLPMSPL 824

Query: 298 PPVPGYGPPPGPPPPQQGPPPPPGP----FPPRPPGPLGPPLTLAPPPHLPGPPPGAPPP 353
              P   PP    P  Q PP PP       P RPP P GP  +++ P       PG PPP
Sbjct: 825 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP-GPDTSVSGPRLTLALAPGPPPP 883

Query: 354 APHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREM 402
                 +    P  +G  +S +  P     Y   P        PP  E+
Sbjct: 884 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 932



 Score = 76.3 bits (186), Expect = 7e-14
 Identities = 59/178 (33%), Positives = 65/178 (36%), Gaps = 26/178 (14%)

Query: 231 PAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG 290
           P+ QTPP     PP    P   PPP Q    PL  P    + PP P   P Q    P   
Sbjct: 521 PSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTP--HLETPPCPAPCPLQAPPSPLTT 578

Query: 291 PLPPGP-----PPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPG 345
           P P  P     PPP     PP    PP QG P PP   P   P P  PP    PP   P 
Sbjct: 579 PPPETPSSIATPPP---QAPPALASPPLQGLPSPP-LSPLATPPPQAPPXLALPPLQAPP 634

Query: 346 PPPGAPPPAPHVNPA---------------FFPPPTNSGMPTSDSRGPPPTDPYGRPP 388
            PP +PP +P   P+               F PPP+            PP  P   PP
Sbjct: 635 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 692



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 64/213 (30%), Positives = 74/213 (34%), Gaps = 43/213 (20%)

Query: 220 PAGPGGPPPPFPAGQTPPRPPLGPP---------GPPGPPGPPPPGQVLPP--------P 262
           P+ P   PP  P  Q P   P  PP          P   P    P Q L          P
Sbjct: 444 PSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAP 503

Query: 263 LAG---PP--NRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPP 317
           L+    PP   +    PP +  P      PPL  LP   PPP+     P   P  +  P 
Sbjct: 504 LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPC 563

Query: 318 PPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRG 377
           P P P    PP PL       PPP  P      PP AP   PA   PP   G+P+     
Sbjct: 564 PAPCPL-QAPPSPL-----TTPPPETPSSIATPPPQAP---PALASPPL-QGLPS----- 608

Query: 378 PPPTDPYGRPPPYDRGDYGPPGREMDTARTPLS 410
            PP  P   PPP       PP   +   + P S
Sbjct: 609 -PPLSPLATPPP-----QAPPXLALPPLQAPPS 635



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 58/191 (30%), Positives = 70/191 (36%), Gaps = 22/191 (11%)

Query: 239 PPLGPPGPPGPPG-PPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPP 297
           PPL       PP    PP  +  PPL   P+     PPP+     P   P L    P  P
Sbjct: 510 PPLETQSSLAPPSLQTPPASLTTPPLENLPSLA---PPPLQTASAPLTTPHLET--PPCP 564

Query: 298 PPVPGYGPP-PGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLP--GPPPGAPPPA 354
            P P   PP P   PP + P     P P  PP    PPL   P P L     PP   PP 
Sbjct: 565 APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPX 624

Query: 355 PHVNPAFFPPPTNSGMPTSDSRGPPP-----------TDPYGRPP-PYDRGDYGPPGR-E 401
             + P   PP   +  P S    P P             P+  PP P  +  + PP    
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 684

Query: 402 MDTARTPLSEA 412
           +  + TP S+A
Sbjct: 685 VSPSATPPSQA 695



 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 52/165 (31%), Positives = 63/165 (38%), Gaps = 11/165 (6%)

Query: 220 PAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLF 279
           P  P  P  P P G    RPP     PP     P  G +   PLA P   G +  P  + 
Sbjct: 263 PRAPAHPSQPKPKGLQALRPP--QVTPPRKDAAPALGPLSSSPLATPSPSGTKARP--VP 318

Query: 280 PGQPFGQPPLGPLPPGPP--PPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTL 337
           P      P    LPP PP   P+P   P P  PP  Q  P PP   P + P  +  P   
Sbjct: 319 PPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ 378

Query: 338 APPPHLPGPPPGAPPPAPHVNPAFFPPPTN---SGMPTSDSRGPP 379
           APP     PP   P      +P+   PP+    S +  + S G P
Sbjct: 379 APPSLQTIPPIQVPHSL--TSPSLQAPPSPLALSSLQATTSLGSP 421



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 56/193 (29%), Positives = 64/193 (33%), Gaps = 48/193 (24%)

Query: 207 FPGAVPGGDRFPGPAGPGGPPPP-------FPAGQTPPRPPLGP-------PGPPGP--- 249
           FPG  P       P  P   PPP        P  Q PP PP  P       P  PGP   
Sbjct: 807 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 866

Query: 250 -----------PGPPPPGQVLP------PPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPL 292
                      PGPPPP    P      P LAG  +     P  +    + +   P G  
Sbjct: 867 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL----RGYDSGPEGGA 922

Query: 293 PPGPPPPVP-------GYGPPPGPPPPQQGPPPPPGPFPPRP-PGPLGPPLTL--APPPH 342
              PPP           +   P PP   +G P  P P+PP   PG      T+     P 
Sbjct: 923 AASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPE 982

Query: 343 LPGPPPGAPPPAP 355
              P PGA  P P
Sbjct: 983 SATPAPGALDPGP 995



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 51/171 (29%), Positives = 56/171 (32%), Gaps = 29/171 (16%)

Query: 220 PAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLF 279
           P+  GG   P     +    PL  P   GP     P     P    P       PP V  
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT- 286

Query: 280 PGQPFGQPPLGPLPPGP-PPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLA 338
           P +    P LGPL   P   P P        PPP     P P   PP PP  L  PL LA
Sbjct: 287 PPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPP--LATPLPLA 344

Query: 339 PPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389
           PP       P APP                 + T  S   PP  P  + PP
Sbjct: 345 PPS------PSAPP----------------SLQTLPS---PPATPPSQAPP 370



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 49/151 (32%), Positives = 53/151 (35%), Gaps = 20/151 (13%)

Query: 243 PPGPPGPPGPPPPG-QVLPPPLAGPPNRGDRPPPPVLFPGQPFGQP-PLGPLPPGPPPPV 300
           P  P  P  P P G Q L PP   PP R D  P        P   P P G      PPP 
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPP-RKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321

Query: 301 PGYGPPPG---PPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHV 357
               P P    P PP   P P   P P  PP       +L   P  P  PP   PP+   
Sbjct: 322 NAATPLPATLPPSPPLATPLPLAPPSPSAPP-------SLQTLPSPPATPPSQAPPSMTT 374

Query: 358 NPAFFPPPTNSGMP-------TSDSRGPPPT 381
            P   PP   +  P       TS S   PP+
Sbjct: 375 PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPS 405



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 72/277 (25%), Positives = 86/277 (31%), Gaps = 53/277 (19%)

Query: 178 GQMSGEGKAGP-PGGSSRAAFPQGGRGRGRFPGAVPGGDRF--PGPAGPGGPPPPFPAGQ 234
           G +S    A P P G+     P         P  +P       P P  P  P  P P+ Q
Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP-PSLQ 355

Query: 235 TPPRPPLGPPGPPGPPG---PP---PPGQVLPPPLAGPPNRG----DRPPPPVLFP---- 280
           T P PP  PP    PP    PP   PP     PP+  P +        PP P+       
Sbjct: 356 TLPSPPATPP-SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQA 414

Query: 281 ----GQPFGQPPLGPLPPGPPPPVPGYGPP--PGPPPPQQGPPPPPGPFPPRPP------ 328
               G P  Q     L   P         P  P   PP   P   P   P  PP      
Sbjct: 415 TTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLS 474

Query: 329 ---GPLGPPLTLAP-------PPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGP 378
               PL  PLT+ P         H P  P  +    P    +   PP+    P S +  P
Sbjct: 475 PAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPP 534

Query: 379 PPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFE 415
               P   PPP            + TA  PL+    E
Sbjct: 535 LENLPSLAPPP------------LQTASAPLTTPHLE 559



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 62/241 (25%), Positives = 72/241 (29%), Gaps = 65/241 (26%)

Query: 232 AGQTPPR--PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPG-----QPF 284
           A +TP    P L  P PPG P PPPP       + G      R P      G      P 
Sbjct: 13  AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72

Query: 285 GQPPLGPL--------PPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRP-----PGPL 331
             P  GP          P   PP  G G      PP +   P P   P R      PGPL
Sbjct: 73  SAPRAGPTRSAGTSSRNPASRPPASGRGE---RAPPAKNTSPGPVSSPGRASGTTRPGPL 129

Query: 332 G-----------------------PPLTLAPPPHLPGPPPGAPPPA-------------- 354
           G                         L+        GP PG P PA              
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189

Query: 355 PHVNPAFFPPPTNSG-----MPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPL 409
           P   P+  P P   G        S+     P+    R P    G   P  R + ++ TPL
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249

Query: 410 S 410
           S
Sbjct: 250 S 250



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 31/102 (30%), Positives = 32/102 (31%), Gaps = 15/102 (14%)

Query: 208  PGAVPGGDRFPGPAGPGGPPPPFP-------AGQTPPRPPLGPPGPPGPPGPPPPGQVLP 260
            P  + G D  P       PPP          A    P PPL   G PG P P PP     
Sbjct: 908  PEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP----- 962

Query: 261  PPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPG 302
               A  P   D         G     P  G L PGP P   G
Sbjct: 963  ---ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSG 1001


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.139    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,106,541
Number of Sequences: 37866
Number of extensions: 4516720
Number of successful extensions: 168060
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2008
Number of HSP's successfully gapped in prelim test: 2079
Number of HSP's that attempted gapping in prelim test: 20670
Number of HSP's gapped (non-prelim): 40182
length of query: 551
length of database: 18,247,518
effective HSP length: 107
effective length of query: 444
effective length of database: 14,195,856
effective search space: 6302960064
effective search space used: 6302960064
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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