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Search of human proteins with 159032029
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|159032029 SUMO1/sentrin specific peptidase 5 [Homo sapiens]
(755 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|159032029 SUMO1/sentrin specific peptidase 5 [Homo sapiens] 1561 0.0
gi|21361499 SUMO1/sentrin/SMT3 specific protease 3 [Homo sapiens] 306 6e-83
gi|7657550 sentrin/SUMO-specific protease 1 [Homo sapiens] 159 9e-39
gi|54607091 SUMO1/sentrin/SMT3 specific protease 2 [Homo sapiens] 143 7e-34
gi|116174736 sentrin/SUMO-specific protease 7 isoform 2 [Homo sa... 59 2e-08
gi|116174746 sentrin/SUMO-specific protease 7 isoform 1 [Homo sa... 59 2e-08
gi|156105703 SUMO1/sentrin specific peptidase 6 isoform 2 [Homo ... 54 4e-07
gi|156105701 SUMO1/sentrin specific peptidase 6 isoform 1 [Homo ... 54 4e-07
gi|33942066 SUMO/sentrin specific peptidase family member 8 [Hom... 45 3e-04
gi|70980547 FYVE-finger-containing Rab5 effector protein rabenos... 37 0.088
gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens] 35 0.26
gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens] 35 0.26
gi|16904383 leucine rich repeat containing 7 [Homo sapiens] 35 0.34
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 34 0.44
gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens] 33 0.75
gi|116284392 mucin 2 precursor [Homo sapiens] 32 2.2
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 32 2.2
gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 32 2.2
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 31 3.7
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 31 3.7
gi|8923040 CDKN2A interacting protein [Homo sapiens] 31 3.7
gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens] 31 4.9
gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens] 31 4.9
gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo s... 31 4.9
gi|149944526 additional sex combs like 3 [Homo sapiens] 31 4.9
gi|221316627 cysteine and glycine-rich protein 1 isoform 2 [Homo... 30 6.3
gi|157837985 kazrin isoform E [Homo sapiens] 30 6.3
gi|65301128 kazrin isoform C [Homo sapiens] 30 6.3
gi|65301130 kazrin isoform B [Homo sapiens] 30 6.3
gi|63999741 kazrin isoform C [Homo sapiens] 30 6.3
>gi|159032029 SUMO1/sentrin specific peptidase 5 [Homo sapiens]
Length = 755
Score = 1561 bits (4042), Expect = 0.0
Identities = 755/755 (100%), Positives = 755/755 (100%)
Query: 1 MKKQRKILWRKGIHLAFSEKWNTGFGGFKKFYFHQHLCILKAKLGRPVTWNRQLRHFQGR 60
MKKQRKILWRKGIHLAFSEKWNTGFGGFKKFYFHQHLCILKAKLGRPVTWNRQLRHFQGR
Sbjct: 1 MKKQRKILWRKGIHLAFSEKWNTGFGGFKKFYFHQHLCILKAKLGRPVTWNRQLRHFQGR 60
Query: 61 KKALQIQKTWIKDEPLCAKTKFNVATQNVSTLSSKVKRKDAKHFISSSKTLLRLQAEKLL 120
KKALQIQKTWIKDEPLCAKTKFNVATQNVSTLSSKVKRKDAKHFISSSKTLLRLQAEKLL
Sbjct: 61 KKALQIQKTWIKDEPLCAKTKFNVATQNVSTLSSKVKRKDAKHFISSSKTLLRLQAEKLL 120
Query: 121 SSAKNSDHEYCREKNLLKAVTDFPSNSALGQANGHRPRTDPQPSDFPMKFNGESQSPGES 180
SSAKNSDHEYCREKNLLKAVTDFPSNSALGQANGHRPRTDPQPSDFPMKFNGESQSPGES
Sbjct: 121 SSAKNSDHEYCREKNLLKAVTDFPSNSALGQANGHRPRTDPQPSDFPMKFNGESQSPGES 180
Query: 181 GTIVVTLNNHKRKGFCYGCCQGPEHHRNGGPLIPKKFQLNQHRRIKLSPLMMYEKLSMIR 240
GTIVVTLNNHKRKGFCYGCCQGPEHHRNGGPLIPKKFQLNQHRRIKLSPLMMYEKLSMIR
Sbjct: 181 GTIVVTLNNHKRKGFCYGCCQGPEHHRNGGPLIPKKFQLNQHRRIKLSPLMMYEKLSMIR 240
Query: 241 FRYRILRSQHFRTKSKVCKLRKAQRSWVQKVTGDHQETRRENGEGGSCSPFPSPEPKDPS 300
FRYRILRSQHFRTKSKVCKLRKAQRSWVQKVTGDHQETRRENGEGGSCSPFPSPEPKDPS
Sbjct: 241 FRYRILRSQHFRTKSKVCKLRKAQRSWVQKVTGDHQETRRENGEGGSCSPFPSPEPKDPS 300
Query: 301 CRHQPYFPDMDSSAVVKGTNSHVPDCHTKGSSFLGKELSLDEAFPDQQNGSATNAWDQSS 360
CRHQPYFPDMDSSAVVKGTNSHVPDCHTKGSSFLGKELSLDEAFPDQQNGSATNAWDQSS
Sbjct: 301 CRHQPYFPDMDSSAVVKGTNSHVPDCHTKGSSFLGKELSLDEAFPDQQNGSATNAWDQSS 360
Query: 361 CSSPKWECTELIHDIPLPEHRSNTMFISETEREIMTLGQENQTSSVSDDRVKLSVSGADT 420
CSSPKWECTELIHDIPLPEHRSNTMFISETEREIMTLGQENQTSSVSDDRVKLSVSGADT
Sbjct: 361 CSSPKWECTELIHDIPLPEHRSNTMFISETEREIMTLGQENQTSSVSDDRVKLSVSGADT 420
Query: 421 SVSSVDGPVSQKAVQNENSYQMEEDGSLKQSILSSELLDHPYCKSPLEAPLVCSGLKLEN 480
SVSSVDGPVSQKAVQNENSYQMEEDGSLKQSILSSELLDHPYCKSPLEAPLVCSGLKLEN
Sbjct: 421 SVSSVDGPVSQKAVQNENSYQMEEDGSLKQSILSSELLDHPYCKSPLEAPLVCSGLKLEN 480
Query: 481 QVGGGKNSQKASPVDDEQLSVCLSGFLDEVMKKYGSLVPLSEKEVLGRLKDVFNEDFSNR 540
QVGGGKNSQKASPVDDEQLSVCLSGFLDEVMKKYGSLVPLSEKEVLGRLKDVFNEDFSNR
Sbjct: 481 QVGGGKNSQKASPVDDEQLSVCLSGFLDEVMKKYGSLVPLSEKEVLGRLKDVFNEDFSNR 540
Query: 541 KPFINREITNYRARHQKCNFRIFYNKHMLDMDDLATLDGQNWLNDQVINMYGELIMDAVP 600
KPFINREITNYRARHQKCNFRIFYNKHMLDMDDLATLDGQNWLNDQVINMYGELIMDAVP
Sbjct: 541 KPFINREITNYRARHQKCNFRIFYNKHMLDMDDLATLDGQNWLNDQVINMYGELIMDAVP 600
Query: 601 DKVHFFNSFFHRQLVTKGYNGVKRWTKKVDLFKKSLLLIPIHLEVHWSLITVTLSNRIIS 660
DKVHFFNSFFHRQLVTKGYNGVKRWTKKVDLFKKSLLLIPIHLEVHWSLITVTLSNRIIS
Sbjct: 601 DKVHFFNSFFHRQLVTKGYNGVKRWTKKVDLFKKSLLLIPIHLEVHWSLITVTLSNRIIS 660
Query: 661 FYDSQGIHFKFCVENIRKYLLTEAREKNRPEFLQGWQTAVTKCIPQQKNDSDCGVFVLQY 720
FYDSQGIHFKFCVENIRKYLLTEAREKNRPEFLQGWQTAVTKCIPQQKNDSDCGVFVLQY
Sbjct: 661 FYDSQGIHFKFCVENIRKYLLTEAREKNRPEFLQGWQTAVTKCIPQQKNDSDCGVFVLQY 720
Query: 721 CKCLALEQPFQFSQEDMPRVRKRIYKELCECRLMD 755
CKCLALEQPFQFSQEDMPRVRKRIYKELCECRLMD
Sbjct: 721 CKCLALEQPFQFSQEDMPRVRKRIYKELCECRLMD 755
>gi|21361499 SUMO1/sentrin/SMT3 specific protease 3 [Homo sapiens]
Length = 574
Score = 306 bits (783), Expect = 6e-83
Identities = 148/274 (54%), Positives = 202/274 (73%), Gaps = 6/274 (2%)
Query: 485 GKNSQKASPVDDEQLSVCLSGFLDEVMKKYGSLVPLSEKEVLGRLKDVFNEDFS--NRKP 542
G+ + + SP+ +E ++ C+ LDE ++ YGSL+PLS EV+ +L+D+F ++FS +RK
Sbjct: 300 GEKAGQHSPLREEHVT-CVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKG 358
Query: 543 FINREITNYRARHQKC---NFRIFYNKHMLDMDDLATLDGQNWLNDQVINMYGELIMDAV 599
+ + I +Y+ FR+ Y +H+L MDDL TL GQNWLNDQV+NMYG+L+MD V
Sbjct: 359 LVLQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTV 418
Query: 600 PDKVHFFNSFFHRQLVTKGYNGVKRWTKKVDLFKKSLLLIPIHLEVHWSLITVTLSNRII 659
P+KVHFFNSFF+ +L TKGY+GVKRWTK VD+F K LLLIPIHLEVHWSLI+V + R I
Sbjct: 419 PEKVHFFNSFFYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTI 478
Query: 660 SFYDSQGIHFKFCVENIRKYLLTEAREKNRPEFLQGWQTAVTKCIPQQKNDSDCGVFVLQ 719
+++DSQ + C ++I KYL EA +K+R +F QGW+ + +Q NDSDCG FVLQ
Sbjct: 479 TYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQ 538
Query: 720 YCKCLALEQPFQFSQEDMPRVRKRIYKELCECRL 753
YCK LAL QPF F+Q+DMP++R++IYKELC C+L
Sbjct: 539 YCKHLALSQPFSFTQQDMPKLRRQIYKELCHCKL 572
>gi|7657550 sentrin/SUMO-specific protease 1 [Homo sapiens]
Length = 643
Score = 159 bits (402), Expect = 9e-39
Identities = 82/188 (43%), Positives = 113/188 (60%), Gaps = 6/188 (3%)
Query: 573 DLATLDGQNWLNDQVINMYGELIMDAVPDK----VHFFNSFFHRQLVTKGYNGVKRWTKK 628
D+ TL+ NWLND++IN Y ++M+ +K VH FN+FF +L T GY VKRWTKK
Sbjct: 456 DIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKK 515
Query: 629 VDLFKKSLLLIPIHLEVHWSLITVTLSNRIISFYDSQGIHFKFCVENIRKYLLTEAREKN 688
VD+F +LL+PIHL VHW L V + I++YDS G + +YL E+ +K
Sbjct: 516 VDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKK 575
Query: 689 RPEF-LQGWQTAVTKC-IPQQKNDSDCGVFVLQYCKCLALEQPFQFSQEDMPRVRKRIYK 746
R EF GWQ K IPQQ N SDCG+F +Y C+ ++P F+Q+ MP RKR+
Sbjct: 576 RKEFDTNGWQLFSKKSQIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVW 635
Query: 747 ELCECRLM 754
E+ +L+
Sbjct: 636 EILHRKLL 643
>gi|54607091 SUMO1/sentrin/SMT3 specific protease 2 [Homo sapiens]
Length = 589
Score = 143 bits (360), Expect = 7e-34
Identities = 86/289 (29%), Positives = 151/289 (52%), Gaps = 12/289 (4%)
Query: 475 GLKLENQVGGGKNSQKASPVDDEQLS--VCLSGFLDEVMKKYGSLVPLSEKEVLGRLKDV 532
G++ EN+ + + P E++S + L + ++++ S++ EK G+ +D
Sbjct: 304 GIRFENE---SRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDR 360
Query: 533 FNEDFSNRKPFINREITNYRARHQKCNFRIFYNKHMLDMDDLATLDGQNWLNDQVINMYG 592
+D + +EI+N + K + D+ TL +WLND+VIN Y
Sbjct: 361 RTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYM 420
Query: 593 ELIMDAVPDK----VHFFNSFFHRQLVTKGYNGVKRWTKKVDLFKKSLLLIPIHLEVHWS 648
L+++ + +H F++FF+ +L + GY VKRWTK V+LF++ ++L+PIH +VHWS
Sbjct: 421 NLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWS 480
Query: 649 LITVTLSNRIISFYDSQGIHFKFCVENIRKYLLTEAREKNRPEF-LQGWQTAVTKC--IP 705
L+ + L + + + DS G E + +YL E++ K + L W K IP
Sbjct: 481 LVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIP 540
Query: 706 QQKNDSDCGVFVLQYCKCLALEQPFQFSQEDMPRVRKRIYKELCECRLM 754
QQ N SDCG+F +Y ++ ++P F+Q MP RK++ E+ +L+
Sbjct: 541 QQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL 589
>gi|116174736 sentrin/SUMO-specific protease 7 isoform 2 [Homo
sapiens]
Length = 985
Score = 58.5 bits (140), Expect = 2e-08
Identities = 53/235 (22%), Positives = 90/235 (38%), Gaps = 86/235 (36%)
Query: 572 DDLATLDGQNWLNDQVINMYGELIM-----DAVPDKVHFFNSFFHRQLVTKGYN------ 620
+DL L+ +LND +I+ Y + ++ D + ++ H F+SFF++ L K N
Sbjct: 700 EDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNLTEDNP 759
Query: 621 ----------GVKRWTKKVDLFKKSLLLIPIHLEVHWSLITV------------------ 652
V+ WT+ +++F K + +P++ HW L +
Sbjct: 760 NLSMAQRRHKRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVS 819
Query: 653 --------------------TLSNRIISFYDSQ------GIHFKFC-------------- 672
T S +S DSQ + K C
Sbjct: 820 QQSQAQQSQNDNKTIDNDLRTTSTLSLSAEDSQSTESNMSVPKKMCKRPCILILDSLKAA 879
Query: 673 -----VENIRKYLLT--EAREKNRPEFLQGWQTAVTKCIPQQKNDSDCGVFVLQY 720
V+N+R+YL E + K +F + + +P+Q N SDCGV++LQY
Sbjct: 880 SVQNTVQNLREYLEVEWEVKLKTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLLQY 934
>gi|116174746 sentrin/SUMO-specific protease 7 isoform 1 [Homo
sapiens]
Length = 1050
Score = 58.5 bits (140), Expect = 2e-08
Identities = 53/235 (22%), Positives = 90/235 (38%), Gaps = 86/235 (36%)
Query: 572 DDLATLDGQNWLNDQVINMYGELIM-----DAVPDKVHFFNSFFHRQLVTKGYN------ 620
+DL L+ +LND +I+ Y + ++ D + ++ H F+SFF++ L K N
Sbjct: 765 EDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNLTEDNP 824
Query: 621 ----------GVKRWTKKVDLFKKSLLLIPIHLEVHWSLITV------------------ 652
V+ WT+ +++F K + +P++ HW L +
Sbjct: 825 NLSMAQRRHKRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVS 884
Query: 653 --------------------TLSNRIISFYDSQ------GIHFKFC-------------- 672
T S +S DSQ + K C
Sbjct: 885 QQSQAQQSQNDNKTIDNDLRTTSTLSLSAEDSQSTESNMSVPKKMCKRPCILILDSLKAA 944
Query: 673 -----VENIRKYLLT--EAREKNRPEFLQGWQTAVTKCIPQQKNDSDCGVFVLQY 720
V+N+R+YL E + K +F + + +P+Q N SDCGV++LQY
Sbjct: 945 SVQNTVQNLREYLEVEWEVKLKTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLLQY 999
>gi|156105703 SUMO1/sentrin specific peptidase 6 isoform 2 [Homo
sapiens]
Length = 1105
Score = 54.3 bits (129), Expect = 4e-07
Identities = 30/101 (29%), Positives = 54/101 (53%), Gaps = 20/101 (19%)
Query: 572 DDLATLDGQNWLNDQVINMYGE-LIMDAVP----DKVHFFNSFFHRQL------------ 614
+DL L+ +LND +I+ Y + L+++ + D++H F+SFF+++L
Sbjct: 664 EDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNHETTN 723
Query: 615 ---VTKGYNGVKRWTKKVDLFKKSLLLIPIHLEVHWSLITV 652
K + VK WT+ VD+F+K + +P++ HW L V
Sbjct: 724 LSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVV 764
Score = 35.8 bits (81), Expect = 0.15
Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
Query: 673 VENIRKYLLTE--AREKNRPEFLQGWQTAVTKCIPQQKNDSDCGVFVLQY 720
V+ +R+YL E ++ ++ F + +PQQ N SDCGV+VLQY
Sbjct: 981 VKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQY 1030
>gi|156105701 SUMO1/sentrin specific peptidase 6 isoform 1 [Homo
sapiens]
Length = 1112
Score = 54.3 bits (129), Expect = 4e-07
Identities = 30/101 (29%), Positives = 54/101 (53%), Gaps = 20/101 (19%)
Query: 572 DDLATLDGQNWLNDQVINMYGE-LIMDAVP----DKVHFFNSFFHRQL------------ 614
+DL L+ +LND +I+ Y + L+++ + D++H F+SFF+++L
Sbjct: 671 EDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNHETTN 730
Query: 615 ---VTKGYNGVKRWTKKVDLFKKSLLLIPIHLEVHWSLITV 652
K + VK WT+ VD+F+K + +P++ HW L V
Sbjct: 731 LSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVV 771
Score = 35.8 bits (81), Expect = 0.15
Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
Query: 673 VENIRKYLLTE--AREKNRPEFLQGWQTAVTKCIPQQKNDSDCGVFVLQY 720
V+ +R+YL E ++ ++ F + +PQQ N SDCGV+VLQY
Sbjct: 988 VKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQY 1037
>gi|33942066 SUMO/sentrin specific peptidase family member 8 [Homo
sapiens]
Length = 212
Score = 44.7 bits (104), Expect = 3e-04
Identities = 45/183 (24%), Positives = 75/183 (40%), Gaps = 28/183 (15%)
Query: 564 YNKHMLDMDDLATLDGQNWLNDQVINMYGELIMDA----VPDKVHFFNSFFHRQL-VTKG 618
Y +L D++ LD +WLND +I E ++ D V F + + + T
Sbjct: 8 YMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSN 67
Query: 619 YNGVKRWTKKVDLFKKSLLLIPIHLE-------VHWSLITVTLSNRIISFYD----SQGI 667
+ + + +DL K ++ + I+ HWSL+ YD S +
Sbjct: 68 PAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSV 127
Query: 668 HFKFCVENIRKYLLTEAREKNRPEFLQGWQTAVTKCIPQQKNDSDCGVFVLQYCKCLALE 727
H K E + +L R+ ++ F V + P Q+N DCG++V+ C AL
Sbjct: 128 HAKQVAEKLEAFL---GRKGDKLAF-------VEEKAPAQQNSYDCGMYVI--CNTEALC 175
Query: 728 QPF 730
Q F
Sbjct: 176 QNF 178
>gi|70980547 FYVE-finger-containing Rab5 effector protein
rabenosyn-5 [Homo sapiens]
Length = 784
Score = 36.6 bits (83), Expect = 0.088
Identities = 35/127 (27%), Positives = 52/127 (40%), Gaps = 13/127 (10%)
Query: 252 RTKSKVCKLRKAQRSWVQ-KVTGDHQETRR-ENGEGGSCSPFPSPEPKDPSCRHQPYFPD 309
R + ++ + R+ +R Q +V H TR + E G PS EP+ H Y D
Sbjct: 519 REQLQMLRERELEREREQFRVASLHTRTRSLDFREIGPFQLEPSREPRT----HLAYALD 574
Query: 310 MDSSAVVKGTNSHVPDCHT-------KGSSFLGKELSLDEAFPDQQNGSATNAWDQSSCS 362
+ SS V T P + G +G+E + P Q G + N +D+ S
Sbjct: 575 LGSSPVPSSTAPKTPSLSSTQPTRVWSGPPAVGQERLPQSSMPQQHEGPSLNPFDEEDLS 634
Query: 363 SPKWECT 369
SP E T
Sbjct: 635 SPMEEAT 641
>gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]
Length = 2540
Score = 35.0 bits (79), Expect = 0.26
Identities = 44/163 (26%), Positives = 69/163 (42%), Gaps = 40/163 (24%)
Query: 353 TNAWDQSSCSSPKWECTELIHDIPLPEHRSNTMFISETEREIMTLGQENQTSSVSDDRVK 412
T+A D +S SS W +E+I + SNT+ S T E ++ +Q + + K
Sbjct: 1400 TSAADTTSVSS--WGGSEVISSL------SNTILAS-TSSECVSSKSVSQPVAQKQE-CK 1449
Query: 413 LSVSGADTSVSSVDGPVSQK---------------------AVQNENSYQME-EDGSLKQ 450
+S + T SS G V Q A Q ++S E E ++K
Sbjct: 1450 VSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKN 1509
Query: 451 SILSSELLDHPYCKSPLEAPLVCSGLKLENQVGGGKNSQKASP 493
LS+ L PL++ ++CS + N VG G+ SQ + P
Sbjct: 1510 QTLSASL--------PLDSTVICSTINKANSVGNGQASQTSQP 1544
>gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens]
Length = 2303
Score = 35.0 bits (79), Expect = 0.26
Identities = 44/163 (26%), Positives = 69/163 (42%), Gaps = 40/163 (24%)
Query: 353 TNAWDQSSCSSPKWECTELIHDIPLPEHRSNTMFISETEREIMTLGQENQTSSVSDDRVK 412
T+A D +S SS W +E+I + SNT+ S T E ++ +Q + + K
Sbjct: 1181 TSAADTTSVSS--WGGSEVISSL------SNTILAS-TSSECVSSKSVSQPVAQKQE-CK 1230
Query: 413 LSVSGADTSVSSVDGPVSQK---------------------AVQNENSYQME-EDGSLKQ 450
+S + T SS G V Q A Q ++S E E ++K
Sbjct: 1231 VSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKN 1290
Query: 451 SILSSELLDHPYCKSPLEAPLVCSGLKLENQVGGGKNSQKASP 493
LS+ L PL++ ++CS + N VG G+ SQ + P
Sbjct: 1291 QTLSASL--------PLDSTVICSTINKANSVGNGQASQTSQP 1325
>gi|16904383 leucine rich repeat containing 7 [Homo sapiens]
Length = 1537
Score = 34.7 bits (78), Expect = 0.34
Identities = 22/84 (26%), Positives = 39/84 (46%)
Query: 369 TELIHDIPLPEHRSNTMFISETEREIMTLGQENQTSSVSDDRVKLSVSGADTSVSSVDGP 428
T +++IPL + S + + ER LG E+ SS+S + + + S GP
Sbjct: 957 TYKVYNIPLENYASGSDHLGSHERPDKMLGPEHGMSSMSRSQSVPMLDDEMLTYGSSKGP 1016
Query: 429 VSQKAVQNENSYQMEEDGSLKQSI 452
QKA + YQ ++ + + S+
Sbjct: 1017 QQQKASMTKKVYQFDQSFNPQGSV 1040
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 34.3 bits (77), Expect = 0.44
Identities = 28/101 (27%), Positives = 39/101 (38%), Gaps = 14/101 (13%)
Query: 275 HQETRRENGEGGSCSPFPSPEPKDPSCRHQPYFPD----------MDSSAVVKGTNSHVP 324
H +R + EG S + DPS P PD + + T+SH P
Sbjct: 617 HSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSP 676
Query: 325 DCHTKGSSFLGKELSLDEAFPDQQNGSATNAWDQSSCSSPK 365
G G+ LS D++ D AT ++SS SS K
Sbjct: 677 STFPSG----GQTLSQDDSQADATTSKATLPGERSSSSSSK 713
>gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]
Length = 466
Score = 33.5 bits (75), Expect = 0.75
Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 11/90 (12%)
Query: 442 MEEDGSLKQSILSSELLDHPYCKSPLEAPLVC-------SGLKLE---NQVGGGKNSQKA 491
M E+ L + LS + P C SP AP + SGL+ ++G K Q+
Sbjct: 1 MAEEQDLSEVELSPVGSEEPRCLSPGSAPSLGPDGGGGGSGLRASPGPGELGKVKKEQQD 60
Query: 492 SPVDDEQLSVCLSGFLDEVMKKYG-SLVPL 520
DD++ VC+ + +V+ Y +LVP+
Sbjct: 61 GEADDDKFPVCIREAVSQVLSGYDWTLVPM 90
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 32.0 bits (71), Expect = 2.2
Identities = 27/125 (21%), Positives = 43/125 (34%), Gaps = 7/125 (5%)
Query: 253 TKSKVCKLRKAQRSWVQKVTGDHQETRRENGEGGSCSPFPSPEPKDPSCRHQPYFPDM-- 310
T + C L +RSW +K Q + ++ C P+P +C H D
Sbjct: 1032 TNPEPCSLNPHRRSWAEK-----QCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGG 1086
Query: 311 DSSAVVKGTNSHVPDCHTKGSSFLGKELSLDEAFPDQQNGSATNAWDQSSCSSPKWECTE 370
D S+ +C +G+ + L F D N W C + +E
Sbjct: 1087 DCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCR 1146
Query: 371 LIHDI 375
I+ I
Sbjct: 1147 TINGI 1151
>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
Length = 2639
Score = 32.0 bits (71), Expect = 2.2
Identities = 27/125 (21%), Positives = 43/125 (34%), Gaps = 7/125 (5%)
Query: 253 TKSKVCKLRKAQRSWVQKVTGDHQETRRENGEGGSCSPFPSPEPKDPSCRHQPYFPDM-- 310
T + C L +RSW +K Q + ++ C P+P +C H D
Sbjct: 933 TNPEPCSLNPHRRSWAEK-----QCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGG 987
Query: 311 DSSAVVKGTNSHVPDCHTKGSSFLGKELSLDEAFPDQQNGSATNAWDQSSCSSPKWECTE 370
D S+ +C +G+ + L F D N W C + +E
Sbjct: 988 DCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCR 1047
Query: 371 LIHDI 375
I+ I
Sbjct: 1048 TINGI 1052
>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
[Homo sapiens]
Length = 1093
Score = 32.0 bits (71), Expect = 2.2
Identities = 35/139 (25%), Positives = 48/139 (34%), Gaps = 41/139 (29%)
Query: 269 QKVTGDHQET--RRENG--------EGGSC----SPFPSPEPKDPSCRHQ---------- 304
Q D QET R E G G C S FP P+ +CR
Sbjct: 846 QGTLSDRQETVVRTEGGPQANGHIESNGVCPRDASHFPEPDTHSVACRQPKLCAGSAYHK 905
Query: 305 --------------PYFPDMDSSAVVKGTNSHVPDCHTKGSSFLGKELSLDEAFPDQQNG 350
P+ + V N+ V DC+++G +F + +S D A P NG
Sbjct: 906 EPWKAMEKAEGTPGPHKMEHGGRVVCSDCNTEV-DCYSRGQAFHPQPVSRDSAQPSAPNG 964
Query: 351 SATNAWDQSSCSSPKWECT 369
DQ SP +C+
Sbjct: 965 PEPGGSDQE--HSPHHQCS 981
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 31.2 bits (69), Expect = 3.7
Identities = 31/109 (28%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 400 ENQTSSVSDDRVKLSVSGADTSVSSVD---GPVSQKAVQNENSYQ-MEEDGSLKQSILSS 455
+ Q SS+ D V ++ GA+ SVS V+ G S+ V+++ S++ M KQ L
Sbjct: 1013 DTQVSSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLIL 1072
Query: 456 ELLDHPYCKSPLEAPLVCSGLKLENQVGGGKNSQKASPVDDEQLSVCLS 504
+ L +S L A KL+ ++ K+ Q + E +CLS
Sbjct: 1073 DHLPSVTKESSLRATQPSENDKLQKELNVLKSEQNDLRLQMEAQRICLS 1121
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 31.2 bits (69), Expect = 3.7
Identities = 31/109 (28%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 400 ENQTSSVSDDRVKLSVSGADTSVSSVD---GPVSQKAVQNENSYQ-MEEDGSLKQSILSS 455
+ Q SS+ D V ++ GA+ SVS V+ G S+ V+++ S++ M KQ L
Sbjct: 1013 DTQVSSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLIL 1072
Query: 456 ELLDHPYCKSPLEAPLVCSGLKLENQVGGGKNSQKASPVDDEQLSVCLS 504
+ L +S L A KL+ ++ K+ Q + E +CLS
Sbjct: 1073 DHLPSVTKESSLRATQPSENDKLQKELNVLKSEQNDLRLQMEAQRICLS 1121
>gi|8923040 CDKN2A interacting protein [Homo sapiens]
Length = 580
Score = 31.2 bits (69), Expect = 3.7
Identities = 57/240 (23%), Positives = 93/240 (38%), Gaps = 36/240 (15%)
Query: 317 KGTNSHVPDCHTKGSSFLGKELSLDEAFPD-----QQNGSATNAWDQSSCSSPKWECTEL 371
K + + PD H S + S++ QQ+GS + + S +S +E+
Sbjct: 229 KASEAEAPDKHGSASFVSLLKSSVNSHMTQSTDSRQQSGSPKKSALEGSSASASQSSSEI 288
Query: 372 IHDIPLPEHRSNTMFISETEREIMTLGQENQTSSVSDDRVKLSVSGADTSVSSVDGPVSQ 431
++PL + SE E +++ ++T+S SG TS +S + VS
Sbjct: 289 --EVPLLGSSGS----SEVELPLLSSKPSSETAS----------SGL-TSKTSSEASVSS 331
Query: 432 KAVQNENS-----YQMEEDGSLKQSILSSELLDHPYCKSPLEAPLVCSGLKLENQVGGGK 486
+N +S + S S+L+S+ S + A L+ S K +Q G
Sbjct: 332 SVAKNSSSSGTSLLTPKSSSSTNTSLLTSK------STSQVAASLLAS--KSSSQTSGSL 383
Query: 487 NSQKASPVDDEQLSVCLSGFLDEVMKKYGSLVPLSEKEVLGRLKDVFNEDFSNRKPFINR 546
S+ S QL+ S S SE V K + NED ++PF NR
Sbjct: 384 VSKSTSLASVSQLASKSSSQTSTSQLPSKSTSQSSESSVKFSCK-LTNEDVKQKQPFFNR 442
>gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens]
Length = 1251
Score = 30.8 bits (68), Expect = 4.9
Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 8/106 (7%)
Query: 428 PVSQKAVQNENSYQMEEDGSLKQSILSSELLDHPYCKSPLEAPLVCSG--LKLENQVGGG 485
P S++ ++ E+S S S L SE ++P K+ A SG +L+ G
Sbjct: 685 PKSKEFIETESS----SSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANG 740
Query: 486 KNSQKASPVDDEQLSVCLSGFLDEVMKKYGSLVPLSEKEVLGRLKD 531
+ +A PV S E+ +++ +LVP E+L LKD
Sbjct: 741 GSGPRA-PVGSINARTT-SDIAKELEEQFYTLVPFGRNELLSPLKD 784
>gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens]
Length = 1226
Score = 30.8 bits (68), Expect = 4.9
Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 8/106 (7%)
Query: 428 PVSQKAVQNENSYQMEEDGSLKQSILSSELLDHPYCKSPLEAPLVCSG--LKLENQVGGG 485
P S++ ++ E+S S S L SE ++P K+ A SG +L+ G
Sbjct: 660 PKSKEFIETESS----SSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANG 715
Query: 486 KNSQKASPVDDEQLSVCLSGFLDEVMKKYGSLVPLSEKEVLGRLKD 531
+ +A PV S E+ +++ +LVP E+L LKD
Sbjct: 716 GSGPRA-PVGSINARTT-SDIAKELEEQFYTLVPFGRNELLSPLKD 759
>gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo
sapiens]
Length = 770
Score = 30.8 bits (68), Expect = 4.9
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 52 RQLRHFQGRKKALQIQKTWIKDEPLCAKTKFNVATQNVSTLSSKVKR---KDAKHFISSS 108
+++ G++ LQ +KT IK++ C + ++ + S+ R K SS
Sbjct: 552 QEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDFYNSYKTQAGSS 611
Query: 109 KTLLRLQAEKLLSSAKNSDHEYCR 132
KT ++E+ SS +NS +CR
Sbjct: 612 KTEKPYKSERHFSSRRNSSDSFCR 635
>gi|149944526 additional sex combs like 3 [Homo sapiens]
Length = 2248
Score = 30.8 bits (68), Expect = 4.9
Identities = 46/203 (22%), Positives = 79/203 (38%), Gaps = 24/203 (11%)
Query: 286 GSCSPFPSPEPKDPSCRHQPYFPDMDSSAVVKGTNSHVPDCHTKGSSFLGKELSLDEAFP 345
G+C+ PSP + S + P + +S T+ + + S DE F
Sbjct: 620 GACTSLPSPGGETQSTSEESCTPASLETTFCSEVSS------TENTDKYNQRNSTDENF- 672
Query: 346 DQQNGSATNAWDQSSCSSPKWECTELIHDIPLPEHRS---NTMFISETEREIMTLGQENQ 402
+ S + S +SP+ L+ ++PL S N SET + L ++
Sbjct: 673 ---HASLMSEISPIS-TSPEISEASLMSNLPLTSEASPVSNLPLTSETS-PMSDLPLTSE 727
Query: 403 TSSVSDDRVKLSVSGADTSVSSVD-----GPVSQKAVQNENSYQMEEDGSLKQSILSSEL 457
TSSVS + ++ T VSS+ P+S ++ ++Q + S+ + LS +
Sbjct: 728 TSSVSS----MLLTSETTFVSSLPLPSETSPISNSSINERMAHQQRKSPSVSEEPLSPQK 783
Query: 458 LDHPYCKSPLEAPLVCSGLKLEN 480
+ PL L L N
Sbjct: 784 DESSATAKPLGENLTSQQKNLSN 806
>gi|221316627 cysteine and glycine-rich protein 1 isoform 2 [Homo
sapiens]
Length = 140
Score = 30.4 bits (67), Expect = 6.3
Identities = 12/27 (44%), Positives = 15/27 (55%)
Query: 151 QANGHRPRTDPQPSDFPMKFNGESQSP 177
+A GHRP T+P S F K G + P
Sbjct: 94 EAPGHRPTTNPNASKFAQKIGGSERCP 120
>gi|157837985 kazrin isoform E [Homo sapiens]
Length = 775
Score = 30.4 bits (67), Expect = 6.3
Identities = 44/220 (20%), Positives = 79/220 (35%), Gaps = 33/220 (15%)
Query: 53 QLRHF-----QGRKKALQIQKTWIKDEPLCAKTKFNV------ATQNVSTLSSKVKRKDA 101
QLR F Q RK++ K K++ L + K+ + AT + + L S++ KD
Sbjct: 172 QLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 231
Query: 102 KHFISSSKTLLRLQAEKLLSSAKNSDHEYCREKNLLK-------AVTDFPSNSALGQA-- 152
+ ++ + Q+ L+ H + D P +A+ Q+
Sbjct: 232 RMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQ 291
Query: 153 ---NGHRP--------RTDPQPSDFPMKFNGESQSPGESGTIVVTLNN--HKRKGFCYGC 199
+ H P R P S P + S + G+ + +N+ H+ C G
Sbjct: 292 TLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTPSDINSPRHRTHSLCNGD 351
Query: 200 CQGPEHHRNGGPLIPKKFQLNQHRRIKLSPLMMYEKLSMI 239
GP P++ L +R K M + +S +
Sbjct: 352 SPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRV 391
>gi|65301128 kazrin isoform C [Homo sapiens]
Length = 327
Score = 30.4 bits (67), Expect = 6.3
Identities = 44/220 (20%), Positives = 79/220 (35%), Gaps = 33/220 (15%)
Query: 53 QLRHF-----QGRKKALQIQKTWIKDEPLCAKTKFNV------ATQNVSTLSSKVKRKDA 101
QLR F Q RK++ K K++ L + K+ + AT + + L S++ KD
Sbjct: 78 QLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
Query: 102 KHFISSSKTLLRLQAEKLLSSAKNSDHEYCREKNLLK-------AVTDFPSNSALGQA-- 152
+ ++ + Q+ L+ H + D P +A+ Q+
Sbjct: 138 RMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQ 197
Query: 153 ---NGHRP--------RTDPQPSDFPMKFNGESQSPGESGTIVVTLNN--HKRKGFCYGC 199
+ H P R P S P + S + G+ + +N+ H+ C G
Sbjct: 198 TLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTPSDINSPRHRTHSLCNGD 257
Query: 200 CQGPEHHRNGGPLIPKKFQLNQHRRIKLSPLMMYEKLSMI 239
GP P++ L +R K M + +S +
Sbjct: 258 SPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRV 297
>gi|65301130 kazrin isoform B [Homo sapiens]
Length = 415
Score = 30.4 bits (67), Expect = 6.3
Identities = 44/220 (20%), Positives = 79/220 (35%), Gaps = 33/220 (15%)
Query: 53 QLRHF-----QGRKKALQIQKTWIKDEPLCAKTKFNV------ATQNVSTLSSKVKRKDA 101
QLR F Q RK++ K K++ L + K+ + AT + + L S++ KD
Sbjct: 166 QLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 225
Query: 102 KHFISSSKTLLRLQAEKLLSSAKNSDHEYCREKNLLK-------AVTDFPSNSALGQA-- 152
+ ++ + Q+ L+ H + D P +A+ Q+
Sbjct: 226 RMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQ 285
Query: 153 ---NGHRP--------RTDPQPSDFPMKFNGESQSPGESGTIVVTLNN--HKRKGFCYGC 199
+ H P R P S P + S + G+ + +N+ H+ C G
Sbjct: 286 TLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTPSDINSPRHRTHSLCNGD 345
Query: 200 CQGPEHHRNGGPLIPKKFQLNQHRRIKLSPLMMYEKLSMI 239
GP P++ L +R K M + +S +
Sbjct: 346 SPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRV 385
>gi|63999741 kazrin isoform C [Homo sapiens]
Length = 327
Score = 30.4 bits (67), Expect = 6.3
Identities = 44/220 (20%), Positives = 79/220 (35%), Gaps = 33/220 (15%)
Query: 53 QLRHF-----QGRKKALQIQKTWIKDEPLCAKTKFNV------ATQNVSTLSSKVKRKDA 101
QLR F Q RK++ K K++ L + K+ + AT + + L S++ KD
Sbjct: 78 QLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDN 137
Query: 102 KHFISSSKTLLRLQAEKLLSSAKNSDHEYCREKNLLK-------AVTDFPSNSALGQA-- 152
+ ++ + Q+ L+ H + D P +A+ Q+
Sbjct: 138 RMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGNQEWVVQADLPLTAAIRQSQQ 197
Query: 153 ---NGHRP--------RTDPQPSDFPMKFNGESQSPGESGTIVVTLNN--HKRKGFCYGC 199
+ H P R P S P + S + G+ + +N+ H+ C G
Sbjct: 198 TLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGDRSSTPSDINSPRHRTHSLCNGD 257
Query: 200 CQGPEHHRNGGPLIPKKFQLNQHRRIKLSPLMMYEKLSMI 239
GP P++ L +R K M + +S +
Sbjct: 258 SPGPVQKNLHNPIVQSLEDLEDQKRKKKKEKMGFGSISRV 297
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,735,092
Number of Sequences: 37866
Number of extensions: 1464281
Number of successful extensions: 4144
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 4106
Number of HSP's gapped (non-prelim): 60
length of query: 755
length of database: 18,247,518
effective HSP length: 110
effective length of query: 645
effective length of database: 14,082,258
effective search space: 9083056410
effective search space used: 9083056410
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.