Guide to the Human Genome
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Search of human proteins with 157820127

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157820127 claudin-like [Homo sapiens]
         (229 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157820127 claudin-like [Homo sapiens]                              472   e-133
gi|162417973 claudin 22 [Homo sapiens]                                230   7e-61
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]                229   1e-60
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]                228   4e-60
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]                228   4e-60
gi|11141861 claudin 9 [Homo sapiens]                                  111   4e-25
gi|10863887 claudin 1 [Homo sapiens]                                  111   6e-25
gi|153792768 claudin 6 [Homo sapiens]                                 110   1e-24
gi|153792186 claudin 7 [Homo sapiens]                                 104   5e-23
gi|195947374 claudin 5 [Homo sapiens]                                 103   9e-23
gi|195947372 claudin 5 [Homo sapiens]                                 103   9e-23
gi|4502875 claudin 3 [Homo sapiens]                                   103   2e-22
gi|40788011 claudin 8 [Homo sapiens]                                  100   8e-22
gi|183979973 claudin 19 isoform a [Homo sapiens]                      100   8e-22
gi|183979975 claudin 19 isoform b [Homo sapiens]                      100   8e-22
gi|4502877 claudin 4 [Homo sapiens]                                   100   1e-21
gi|225703142 claudin 14 [Homo sapiens]                                 98   7e-21
gi|21536294 claudin 14 [Homo sapiens]                                  98   7e-21
gi|225703138 claudin 14 [Homo sapiens]                                 98   7e-21
gi|6912314 claudin 14 [Homo sapiens]                                   98   7e-21
gi|225703140 claudin 14 [Homo sapiens]                                 98   7e-21
gi|6912316 claudin 17 [Homo sapiens]                                   97   1e-20
gi|9966781 claudin 2 [Homo sapiens]                                    92   4e-19
gi|7656981 claudin 15 [Homo sapiens]                                   89   4e-18
gi|50345279 claudin 18 isoform 2 [Homo sapiens]                        82   4e-16
gi|7705961 claudin 18 isoform 1 [Homo sapiens]                         81   8e-16
gi|5921465 claudin 10 isoform b [Homo sapiens]                         70   1e-12
gi|47716519 claudin 20 [Homo sapiens]                                  67   1e-11
gi|33598916 claudin 10 isoform a [Homo sapiens]                        56   3e-08
gi|124107616 claudin 23 [Homo sapiens]                                 54   9e-08

>gi|157820127 claudin-like [Homo sapiens]
          Length = 229

 Score =  472 bits (1214), Expect = e-133
 Identities = 229/229 (100%), Positives = 229/229 (100%)

Query: 1   MAWSFRAKVQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWIMGIWEVCVDREEV 60
           MAWSFRAKVQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWIMGIWEVCVDREEV
Sbjct: 1   MAWSFRAKVQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWIMGIWEVCVDREEV 60

Query: 61  ATVCKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGL 120
           ATVCKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGL
Sbjct: 61  ATVCKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGL 120

Query: 121 LGRTLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGG 180
           LGRTLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGG
Sbjct: 121 LGRTLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGG 180

Query: 181 LLLIFSACLGKEDVPFPLMAGPTVPLSCAPVEESDGSFHLMLRPRNLVI 229
           LLLIFSACLGKEDVPFPLMAGPTVPLSCAPVEESDGSFHLMLRPRNLVI
Sbjct: 181 LLLIFSACLGKEDVPFPLMAGPTVPLSCAPVEESDGSFHLMLRPRNLVI 229


>gi|162417973 claudin 22 [Homo sapiens]
          Length = 220

 Score =  230 bits (587), Expect = 7e-61
 Identities = 108/188 (57%), Positives = 136/188 (72%)

Query: 1   MAWSFRAKVQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWIMGIWEVCVDREEV 60
           MA  FR   QL G+ LSLLGWV SC+T  LP WK LNL+LNEME W MG+W+ CV +EEV
Sbjct: 1   MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60

Query: 61  ATVCKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGL 120
              CK F+SFL+LP EL+V+RILM  S+GLG LGLL+  FG +C +    +   KRRL +
Sbjct: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120

Query: 121 LGRTLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGG 180
           LG  L  ++  T L+PVSWVAH T+Q+FWD+++PD +PRWEFG AL+LGW AG+ L LGG
Sbjct: 121 LGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180

Query: 181 LLLIFSAC 188
            LL  +AC
Sbjct: 181 CLLHCAAC 188


>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score =  229 bits (584), Expect = 1e-60
 Identities = 108/188 (57%), Positives = 137/188 (72%)

Query: 1   MAWSFRAKVQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWIMGIWEVCVDREEV 60
           MA  FR  +Q  GLLLSLLGW+ S +TT LP WK LNL+LNEME W MG+W+ CV +EEV
Sbjct: 1   MALIFRTAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60

Query: 61  ATVCKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGL 120
              CK F+SFL+LP EL+V+RILM  S+GLG LGLL+  FG +C +    +   KRRL +
Sbjct: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120

Query: 121 LGRTLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGG 180
           LG  L  ++  T L+PVSWVAH T+Q+FWD+++PD +PRWEFG AL+LGW AG+ L LGG
Sbjct: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180

Query: 181 LLLIFSAC 188
            LL  +AC
Sbjct: 181 CLLNCAAC 188


>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score =  228 bits (580), Expect = 4e-60
 Identities = 107/188 (56%), Positives = 136/188 (72%)

Query: 1   MAWSFRAKVQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWIMGIWEVCVDREEV 60
           MA  FR  +Q  GLLLS LGW+ S +TT LP WK LNL+LNEME W MG+W+ CV +EEV
Sbjct: 1   MALIFRTAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60

Query: 61  ATVCKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGL 120
              CK F+SFL+LP EL+V+RILM  S+GLG LGLL+  FG +C +    +   KRRL +
Sbjct: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120

Query: 121 LGRTLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGG 180
           LG  L  ++  T L+PVSWVAH T+Q+FWD+++PD +PRWEFG AL+LGW AG+ L LGG
Sbjct: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180

Query: 181 LLLIFSAC 188
            LL  +AC
Sbjct: 181 CLLNCAAC 188


>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score =  228 bits (580), Expect = 4e-60
 Identities = 107/188 (56%), Positives = 136/188 (72%)

Query: 1   MAWSFRAKVQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWIMGIWEVCVDREEV 60
           MA  FR  +Q  GLLLS LGW+ S +TT LP WK LNL+LNEME W MG+W+ CV +EEV
Sbjct: 1   MALIFRTAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEV 60

Query: 61  ATVCKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGL 120
              CK F+SFL+LP EL+V+RILM  S+GLG LGLL+  FG +C +    +   KRRL +
Sbjct: 61  GMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLI 120

Query: 121 LGRTLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGG 180
           LG  L  ++  T L+PVSWVAH T+Q+FWD+++PD +PRWEFG AL+LGW AG+ L LGG
Sbjct: 121 LGGILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGG 180

Query: 181 LLLIFSAC 188
            LL  +AC
Sbjct: 181 CLLNCAAC 188


>gi|11141861 claudin 9 [Homo sapiens]
          Length = 217

 Score =  111 bits (278), Expect = 4e-25
 Identities = 69/179 (38%), Positives = 97/179 (54%), Gaps = 7/179 (3%)

Query: 9   VQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMET----WIMGIWEVCVDREEVATVC 64
           ++L G+ L++LGW+ + V+  LP WK      N +      W  G+W  CV +      C
Sbjct: 6   LELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVW-EGLWMSCVVQSTGQMQC 64

Query: 65  KAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRT 124
           K ++S L+LPQ+LQ AR L V +  L LLGLL+   G++C          K R+ L    
Sbjct: 65  KVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGA-KARIVLTAGV 123

Query: 125 LEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLL 183
           +   A    L+PV W AHA IQDF++  + + + R E G +LYLGWAA   L LGG LL
Sbjct: 124 ILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKR-ELGASLYLGWAAAALLMLGGGLL 181


>gi|10863887 claudin 1 [Homo sapiens]
          Length = 211

 Score =  111 bits (277), Expect = 6e-25
 Identities = 64/194 (32%), Positives = 98/194 (50%), Gaps = 4/194 (2%)

Query: 7   AKVQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMET---WIMGIWEVCVDREEVATV 63
           A +QL G +L+ LGW+ + V+T LPQW+  +   + + T      G+W  CV +      
Sbjct: 4   AGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQ 63

Query: 64  CKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGR 123
           CK F+S L+L   LQ  R LMV    LG++ + + + G +C +      V K R+ ++G 
Sbjct: 64  CKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGG 123

Query: 124 TLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLL 183
            +   A    L+  +W  +  +Q+F+D   P +  R+EFG AL+ GWAA     LGG LL
Sbjct: 124 AIFLLAGLAILVATAWYGNRIVQEFYDPMTP-VNARYEFGQALFTGWAAASLCLLGGALL 182

Query: 184 IFSACLGKEDVPFP 197
             S        P P
Sbjct: 183 CCSCPRKTTSYPTP 196


>gi|153792768 claudin 6 [Homo sapiens]
          Length = 220

 Score =  110 bits (275), Expect = 1e-24
 Identities = 74/198 (37%), Positives = 103/198 (52%), Gaps = 7/198 (3%)

Query: 7   AKVQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMET----WIMGIWEVCVDREEVAT 62
           A +Q+ G++L+LLGWV   V+  LP WK      N +      W  G+W  CV +     
Sbjct: 4   AGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVW-EGLWMSCVVQSTGQM 62

Query: 63  VCKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLG 122
            CK ++S L+LPQ+LQ AR L V +  + L GLL+   G++C      +   K RL L  
Sbjct: 63  QCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEK-DSKARLVLTS 121

Query: 123 RTLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLL 182
             +   +   TL+PV W AHA I+DF++  + +   R E G +LYLGWAA   L LGG L
Sbjct: 122 GIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKR-ELGASLYLGWAASGLLLLGGGL 180

Query: 183 LIFSACLGKEDVPFPLMA 200
           L  +   G    P   MA
Sbjct: 181 LCCTCPSGGSQGPSHYMA 198


>gi|153792186 claudin 7 [Homo sapiens]
          Length = 211

 Score =  104 bits (260), Expect = 5e-23
 Identities = 69/202 (34%), Positives = 100/202 (49%), Gaps = 10/202 (4%)

Query: 9   VQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMET---WIMGIWEVCVDREEVATVCK 65
           +QL G  ++LLGWV     T +PQW+  +   + + T      G+W  CV +      CK
Sbjct: 6   LQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSCK 65

Query: 66  AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
            ++S L+L   LQ  R LMV S  LG L + + + G +C +      V K R+ + G  +
Sbjct: 66  MYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGGII 125

Query: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIF 185
              A    L+  SW  H  + DF++  IP  I ++EFG A+++GWA    + LGG LL  
Sbjct: 126 FIVAGLAALVACSWYGHQIVTDFYNPLIPTNI-KYEFGPAIFIGWAGSALVILGGALLSC 184

Query: 186 SACLGKEDVPFPLMAGPTVPLS 207
           S C G E       AG  VP S
Sbjct: 185 S-CPGNES-----KAGYRVPRS 200


>gi|195947374 claudin 5 [Homo sapiens]
          Length = 303

 Score =  103 bits (258), Expect = 9e-23
 Identities = 64/197 (32%), Positives = 103/197 (52%), Gaps = 7/197 (3%)

Query: 7   AKVQLGGLLLSLLGWVCSCVTTILPQWKT---LNLELNEMETWIMGIWEVCVDREEVATV 63
           A +++ GL+L L+GW    +   LP W+    L+  +   +T   G+W  CV +      
Sbjct: 89  AALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQ 148

Query: 64  CKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGR 123
           CK ++S L+L  E+Q AR L V++  L  + L +   G++C          K R+ L G 
Sbjct: 149 CKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKARVALTGG 207

Query: 124 TLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLL 183
            L        L+P+ W A+  +++F+D S+P +  ++E G ALY+GWAA   L +GG LL
Sbjct: 208 VLYLFCGLLALVPLCWFANIVVREFYDPSVP-VSQKYELGAALYIGWAATALLMVGGCLL 266

Query: 184 IFSA--CLGKEDVPFPL 198
              A  C G+ D+ FP+
Sbjct: 267 CCGAWVCTGRPDLSFPV 283


>gi|195947372 claudin 5 [Homo sapiens]
          Length = 303

 Score =  103 bits (258), Expect = 9e-23
 Identities = 64/197 (32%), Positives = 103/197 (52%), Gaps = 7/197 (3%)

Query: 7   AKVQLGGLLLSLLGWVCSCVTTILPQWKT---LNLELNEMETWIMGIWEVCVDREEVATV 63
           A +++ GL+L L+GW    +   LP W+    L+  +   +T   G+W  CV +      
Sbjct: 89  AALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQ 148

Query: 64  CKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGR 123
           CK ++S L+L  E+Q AR L V++  L  + L +   G++C          K R+ L G 
Sbjct: 149 CKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTC-VAPGPAKARVALTGG 207

Query: 124 TLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLL 183
            L        L+P+ W A+  +++F+D S+P +  ++E G ALY+GWAA   L +GG LL
Sbjct: 208 VLYLFCGLLALVPLCWFANIVVREFYDPSVP-VSQKYELGAALYIGWAATALLMVGGCLL 266

Query: 184 IFSA--CLGKEDVPFPL 198
              A  C G+ D+ FP+
Sbjct: 267 CCGAWVCTGRPDLSFPV 283


>gi|4502875 claudin 3 [Homo sapiens]
          Length = 220

 Score =  103 bits (256), Expect = 2e-22
 Identities = 61/181 (33%), Positives = 97/181 (53%), Gaps = 5/181 (2%)

Query: 9   VQLGGLLLSLLGWVCSCVTTILPQWKT---LNLELNEMETWIMGIWEVCVDREEVATVCK 65
           +++ G  L++LGW+ + V   LP W+    +   +   +    G+W  CV +      CK
Sbjct: 5   LEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCK 64

Query: 66  AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
            ++S L+LPQ+LQ AR L+V +  L   GLL+   G++C    +     K ++ ++   L
Sbjct: 65  VYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDD-TAKAKITIVAGVL 123

Query: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIF 185
              A+  TL+PVSW A+  I+DF++  +P+   R E G  LY+GWAA     LGG LL  
Sbjct: 124 FLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKR-EMGAGLYVGWAAAALQLLGGALLCC 182

Query: 186 S 186
           S
Sbjct: 183 S 183


>gi|40788011 claudin 8 [Homo sapiens]
          Length = 225

 Score =  100 bits (250), Expect = 8e-22
 Identities = 58/187 (31%), Positives = 95/187 (50%), Gaps = 4/187 (2%)

Query: 9   VQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEM---ETWIMGIWEVCVDREEVATVCK 65
           +++ GL L  +G V +   T++PQW+      N +   E +  G+W  CV +  +   CK
Sbjct: 6   LEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANIRMQCK 65

Query: 66  AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
            ++S L+L  +LQ AR LM A+  +  L  ++   G +C +        K  + L    +
Sbjct: 66  IYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILLTAGII 125

Query: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIF 185
                   L+PVSWVA+A I+DF+ +SI ++  + E G ALYLGW   + L +GG L   
Sbjct: 126 FIITGMVVLIPVSWVANAIIRDFY-NSIVNVAQKRELGEALYLGWTTALVLIVGGALFCC 184

Query: 186 SACLGKE 192
             C  ++
Sbjct: 185 VFCCNEK 191


>gi|183979973 claudin 19 isoform a [Homo sapiens]
          Length = 224

 Score =  100 bits (250), Expect = 8e-22
 Identities = 62/178 (34%), Positives = 92/178 (51%), Gaps = 4/178 (2%)

Query: 9   VQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWI---MGIWEVCVDREEVATVCK 65
           +QL G  L+L GWV    +T LPQWK  +   + + T +    G+W  C  +      CK
Sbjct: 6   LQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQCK 65

Query: 66  AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
            ++S L+L   +Q AR LMV +  LG + ++L   G +C +      + K R+ + G  L
Sbjct: 66  LYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGAL 125

Query: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLL 183
              A   TL  VSW A    Q+F++ S P +  R+EFG AL++GWA+     LGG  L
Sbjct: 126 FILAGLCTLTAVSWYATLVTQEFFNPSTP-VNARYEFGPALFVGWASAGLAVLGGSFL 182


>gi|183979975 claudin 19 isoform b [Homo sapiens]
          Length = 211

 Score =  100 bits (250), Expect = 8e-22
 Identities = 62/178 (34%), Positives = 92/178 (51%), Gaps = 4/178 (2%)

Query: 9   VQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWI---MGIWEVCVDREEVATVCK 65
           +QL G  L+L GWV    +T LPQWK  +   + + T +    G+W  C  +      CK
Sbjct: 6   LQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQCK 65

Query: 66  AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
            ++S L+L   +Q AR LMV +  LG + ++L   G +C +      + K R+ + G  L
Sbjct: 66  LYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGAL 125

Query: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLL 183
              A   TL  VSW A    Q+F++ S P +  R+EFG AL++GWA+     LGG  L
Sbjct: 126 FILAGLCTLTAVSWYATLVTQEFFNPSTP-VNARYEFGPALFVGWASAGLAVLGGSFL 182


>gi|4502877 claudin 4 [Homo sapiens]
          Length = 209

 Score =  100 bits (249), Expect = 1e-21
 Identities = 63/191 (32%), Positives = 99/191 (51%), Gaps = 6/191 (3%)

Query: 9   VQLGGLLLSLLGWVCSCVTTILPQWKT---LNLELNEMETWIMGIWEVCVDREEVATVCK 65
           +Q+ G+ L++LGW+   +   LP W+    +   +   +T   G+W  CV +      CK
Sbjct: 6   LQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCK 65

Query: 66  AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
            ++S L+LPQ+LQ AR L++ S  +  LG+LL   G +C          K +  ++   +
Sbjct: 66  VYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESA-KAKTMIVAGVV 124

Query: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIF 185
              A    ++PVSW AH  IQDF++  +     R E G +LY+GWAA   L LGG LL  
Sbjct: 125 FLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKR-EMGASLYVGWAASGLLLLGGGLLCC 183

Query: 186 SACLGKEDVPF 196
           + C  + D P+
Sbjct: 184 N-CPPRTDKPY 193


>gi|225703142 claudin 14 [Homo sapiens]
          Length = 239

 Score = 97.8 bits (242), Expect = 7e-21
 Identities = 70/217 (32%), Positives = 111/217 (51%), Gaps = 12/217 (5%)

Query: 9   VQLGGLLLSLLGWVCSCVTTILPQWK-TLNLELNEME--TWIMGIWEVCVDREEVATVCK 65
           VQL G LLS LG V + +TTILP W+ T ++  N +   +++ G+W  CV        C+
Sbjct: 6   VQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQ 65

Query: 66  AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
            + S L+LPQ+LQ AR LMV S  L  +       G +C +  +     K    +LG TL
Sbjct: 66  IYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAK-GTPAKTTFAILGGTL 124

Query: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIF 185
              A    ++ VSW  +  +Q+F++  +P  + ++E G ALYLG+ +     +GG LL  
Sbjct: 125 FILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLLCL 183

Query: 186 SACLGKEDVPF-PLMAGP---TVPLSCAPVEESDGSF 218
           S    +++ P+ P  A P   T   + AP  +   ++
Sbjct: 184 SC---QDEAPYRPYQAPPRATTTTANTAPAYQPPAAY 217


>gi|21536294 claudin 14 [Homo sapiens]
          Length = 239

 Score = 97.8 bits (242), Expect = 7e-21
 Identities = 70/217 (32%), Positives = 111/217 (51%), Gaps = 12/217 (5%)

Query: 9   VQLGGLLLSLLGWVCSCVTTILPQWK-TLNLELNEME--TWIMGIWEVCVDREEVATVCK 65
           VQL G LLS LG V + +TTILP W+ T ++  N +   +++ G+W  CV        C+
Sbjct: 6   VQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQ 65

Query: 66  AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
            + S L+LPQ+LQ AR LMV S  L  +       G +C +  +     K    +LG TL
Sbjct: 66  IYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAK-GTPAKTTFAILGGTL 124

Query: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIF 185
              A    ++ VSW  +  +Q+F++  +P  + ++E G ALYLG+ +     +GG LL  
Sbjct: 125 FILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLLCL 183

Query: 186 SACLGKEDVPF-PLMAGP---TVPLSCAPVEESDGSF 218
           S    +++ P+ P  A P   T   + AP  +   ++
Sbjct: 184 SC---QDEAPYRPYQAPPRATTTTANTAPAYQPPAAY 217


>gi|225703138 claudin 14 [Homo sapiens]
          Length = 239

 Score = 97.8 bits (242), Expect = 7e-21
 Identities = 70/217 (32%), Positives = 111/217 (51%), Gaps = 12/217 (5%)

Query: 9   VQLGGLLLSLLGWVCSCVTTILPQWK-TLNLELNEME--TWIMGIWEVCVDREEVATVCK 65
           VQL G LLS LG V + +TTILP W+ T ++  N +   +++ G+W  CV        C+
Sbjct: 6   VQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQ 65

Query: 66  AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
            + S L+LPQ+LQ AR LMV S  L  +       G +C +  +     K    +LG TL
Sbjct: 66  IYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAK-GTPAKTTFAILGGTL 124

Query: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIF 185
              A    ++ VSW  +  +Q+F++  +P  + ++E G ALYLG+ +     +GG LL  
Sbjct: 125 FILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLLCL 183

Query: 186 SACLGKEDVPF-PLMAGP---TVPLSCAPVEESDGSF 218
           S    +++ P+ P  A P   T   + AP  +   ++
Sbjct: 184 SC---QDEAPYRPYQAPPRATTTTANTAPAYQPPAAY 217


>gi|6912314 claudin 14 [Homo sapiens]
          Length = 239

 Score = 97.8 bits (242), Expect = 7e-21
 Identities = 70/217 (32%), Positives = 111/217 (51%), Gaps = 12/217 (5%)

Query: 9   VQLGGLLLSLLGWVCSCVTTILPQWK-TLNLELNEME--TWIMGIWEVCVDREEVATVCK 65
           VQL G LLS LG V + +TTILP W+ T ++  N +   +++ G+W  CV        C+
Sbjct: 6   VQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQ 65

Query: 66  AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
            + S L+LPQ+LQ AR LMV S  L  +       G +C +  +     K    +LG TL
Sbjct: 66  IYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAK-GTPAKTTFAILGGTL 124

Query: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIF 185
              A    ++ VSW  +  +Q+F++  +P  + ++E G ALYLG+ +     +GG LL  
Sbjct: 125 FILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLLCL 183

Query: 186 SACLGKEDVPF-PLMAGP---TVPLSCAPVEESDGSF 218
           S    +++ P+ P  A P   T   + AP  +   ++
Sbjct: 184 SC---QDEAPYRPYQAPPRATTTTANTAPAYQPPAAY 217


>gi|225703140 claudin 14 [Homo sapiens]
          Length = 239

 Score = 97.8 bits (242), Expect = 7e-21
 Identities = 70/217 (32%), Positives = 111/217 (51%), Gaps = 12/217 (5%)

Query: 9   VQLGGLLLSLLGWVCSCVTTILPQWK-TLNLELNEME--TWIMGIWEVCVDREEVATVCK 65
           VQL G LLS LG V + +TTILP W+ T ++  N +   +++ G+W  CV        C+
Sbjct: 6   VQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQ 65

Query: 66  AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
            + S L+LPQ+LQ AR LMV S  L  +       G +C +  +     K    +LG TL
Sbjct: 66  IYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAK-GTPAKTTFAILGGTL 124

Query: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIF 185
              A    ++ VSW  +  +Q+F++  +P  + ++E G ALYLG+ +     +GG LL  
Sbjct: 125 FILAGLLCMVAVSWTTNDVVQNFYNPLLPSGM-KFEIGQALYLGFISSSLSLIGGTLLCL 183

Query: 186 SACLGKEDVPF-PLMAGP---TVPLSCAPVEESDGSF 218
           S    +++ P+ P  A P   T   + AP  +   ++
Sbjct: 184 SC---QDEAPYRPYQAPPRATTTTANTAPAYQPPAAY 217


>gi|6912316 claudin 17 [Homo sapiens]
          Length = 224

 Score = 96.7 bits (239), Expect = 1e-20
 Identities = 63/187 (33%), Positives = 93/187 (49%), Gaps = 4/187 (2%)

Query: 9   VQLGGLLLSLLGWVCSCVTTILPQWKT---LNLELNEMETWIMGIWEVCVDREEVATVCK 65
           +Q+ GL+L  LG V +  TT+LPQW+    +   +   E    G+W  C+ +  V   CK
Sbjct: 6   LQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARVRLQCK 65

Query: 66  AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
            + S L+LP  L+ AR LM  +  L L+ LL+   G +  Q        K  L      L
Sbjct: 66  FYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLGTSGVL 125

Query: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIF 185
                   L+PVSW A+  I+DF++ +I  I  + E G AL+LGWA+   L +GG LL  
Sbjct: 126 FILTGIFVLIPVSWTANIIIRDFYNPAI-HIGQKRELGAALFLGWASAAVLFIGGGLLCG 184

Query: 186 SACLGKE 192
             C  ++
Sbjct: 185 FCCCNRK 191


>gi|9966781 claudin 2 [Homo sapiens]
          Length = 230

 Score = 92.0 bits (227), Expect = 4e-19
 Identities = 54/181 (29%), Positives = 89/181 (49%), Gaps = 5/181 (2%)

Query: 9   VQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWI---MGIWEVCVDREEVATVCK 65
           +QL G +L LLG + + V  +LP WKT +     + T +    G+W  C       T C 
Sbjct: 6   LQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGITQCD 65

Query: 66  AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
            + + L LP ++Q A+ +MV S  +  L  ++   G  C  F +     K R+ + G   
Sbjct: 66  IYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRA-KDRVAVAGGVF 124

Query: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIF 185
                    +PV+W  H  ++DF+   +PD + ++E G ALYLG  + +F  + G++L F
Sbjct: 125 FILGGLLGFIPVAWNLHGILRDFYSPLVPDSM-KFEIGEALYLGIISSLFSLIAGIILCF 183

Query: 186 S 186
           S
Sbjct: 184 S 184


>gi|7656981 claudin 15 [Homo sapiens]
          Length = 228

 Score = 88.6 bits (218), Expect = 4e-18
 Identities = 63/210 (30%), Positives = 92/210 (43%), Gaps = 5/210 (2%)

Query: 9   VQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWIM--GIWEVCVDREEVATVCKA 66
           V+  G  ++ +G +   VT     W+   +  N + T  +   +W  C         C  
Sbjct: 5   VETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYNCWE 64

Query: 67  FESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTLE 126
           F S L+L   +Q  R LM+ +  LG LGLLL   G  C     +    K +L      L 
Sbjct: 65  FPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGALH 124

Query: 127 ASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIFS 186
             A    ++ +SW A    +DF+D   P    ++E G ALYLGW+A +   LGGL L  +
Sbjct: 125 ILAGICGMVAISWYAFNITRDFFDPLYPG--TKYELGPALYLGWSASLISILGGLCLCSA 182

Query: 187 ACLGKEDVPFPLMAGP-TVPLSCAPVEESD 215
            C G ++ P      P   P+S  PV  SD
Sbjct: 183 CCCGSDEDPAASARRPYQAPVSVMPVATSD 212


>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
          Length = 261

 Score = 82.0 bits (201), Expect = 4e-16
 Identities = 52/190 (27%), Positives = 85/190 (44%), Gaps = 13/190 (6%)

Query: 13  GLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWI--MGIWEVCVDREEVATVCKAFESF 70
           G ++SL+G       T + QW T +L  N +       G+W  CV      T C+ + + 
Sbjct: 10  GFVVSLIGIAGIIAATCMDQWSTQDLYNNPVTAVFNYQGLWRSCVRESSGFTECRGYFTL 69

Query: 71  LSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTLEASAS 130
           L LP  LQ  R LM+    LG +GLL+  F  +C +   +    K  + L    +   + 
Sbjct: 70  LGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFIVSG 129

Query: 131 ATTLLPVSWVAHATIQDFWDDS----------IPDIIPRWEFGGALYLGWAAGIFLALGG 180
              +  VS  A+  + +FW  +          +  +  R+ FG AL++GW AG    +GG
Sbjct: 130 LCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGLTLIGG 189

Query: 181 LLLIFSACLG 190
           +++   AC G
Sbjct: 190 VMMCI-ACRG 198


>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
          Length = 261

 Score = 80.9 bits (198), Expect = 8e-16
 Identities = 53/193 (27%), Positives = 87/193 (45%), Gaps = 13/193 (6%)

Query: 10  QLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMETWIM--GIWEVCVDREEVATVCKAF 67
           Q+   LLS+LG       T +  W T +L  N + +     G+W  CV +    T C+ +
Sbjct: 7   QVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGFTECRPY 66

Query: 68  ESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTLEA 127
            + L LP  LQ  R LM+    LG +GLL+  F  +C +   +    K  + L    +  
Sbjct: 67  FTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFI 126

Query: 128 SASATTLLPVSWVAHATIQDFWDDS----------IPDIIPRWEFGGALYLGWAAGIFLA 177
            +    +  VS  A+  + +FW  +          +  +  R+ FG AL++GW AG    
Sbjct: 127 VSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGLTL 186

Query: 178 LGGLLLIFSACLG 190
           +GG+++   AC G
Sbjct: 187 IGGVMMCI-ACRG 198


>gi|5921465 claudin 10 isoform b [Homo sapiens]
          Length = 228

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 46/174 (26%), Positives = 80/174 (45%), Gaps = 5/174 (2%)

Query: 15  LLSLLGWVCSCVTTILPQWK--TLNLELNEMETWIMGIWEVCVDREEVATVCKAFESFLS 72
           ++S+ GWV    T     WK  T++  +    T+   +W+ CV      + CK F S L+
Sbjct: 12  MVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNCKDFPSMLA 71

Query: 73  LPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTLEASASAT 132
           L   +Q  R LM+A+  LG  G +   FG +C +        K ++  L   +   +   
Sbjct: 72  LDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKA-KAKIACLAGIVFILSGLC 130

Query: 133 TLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIFS 186
           ++   S  A+    +F+D     +  ++E G AL++GWA      +GG++  FS
Sbjct: 131 SMTGCSLYANKITTEFFDPLF--VEQKYELGAALFIGWAGASLCIIGGVIFCFS 182


>gi|47716519 claudin 20 [Homo sapiens]
          Length = 219

 Score = 67.0 bits (162), Expect = 1e-11
 Identities = 51/183 (27%), Positives = 84/183 (45%), Gaps = 5/183 (2%)

Query: 7   AKVQLGGLLLSLLGWVCSCVTTILPQWKT-LNLELNEMETWIM--GIWEVCVDREEVATV 63
           A +QL   +L+L G       T+LP WK  ++++ N +   +   G+W  C         
Sbjct: 4   AGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTGMFS 63

Query: 64  CKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGR 123
           C    S LSLP  +Q AR  MV +  L  LG+   + G +C +    R   K      G 
Sbjct: 64  CALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRET-KSHASFAGG 122

Query: 124 TLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLL 183
               SA  ++L+   W     I +F D ++P+   + E GGA+Y+G+ + + L + G++ 
Sbjct: 123 VCFMSAGISSLISTVWYTKEIIANFLDLTVPE-SNKHEPGGAIYIGFISAMLLFISGMIF 181

Query: 184 IFS 186
             S
Sbjct: 182 CTS 184


>gi|33598916 claudin 10 isoform a [Homo sapiens]
          Length = 226

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 40/182 (21%), Positives = 78/182 (42%), Gaps = 5/182 (2%)

Query: 7   AKVQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEME-TWI-MGIWEVCVDREEVATVC 64
           ++ Q+  L+  + G+      T   +WK      + +  TW+  G+W  C      +  C
Sbjct: 2   SRAQIWALVSGVGGFGALVAATTSNEWKVTTRASSVITATWVYQGLWMNCAGNALGSFHC 61

Query: 65  KAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRT 124
           +   +   +   +Q  R LM+A+  LG  G +   FG +C +        K ++  L   
Sbjct: 62  RPHFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKA-KAKIACLAGI 120

Query: 125 LEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLI 184
           +   +   ++   S  A+    +F+D     +  ++E G AL++GWA      +GG++  
Sbjct: 121 VFILSGLCSMTGCSLYANKITTEFFDPLF--VEQKYELGAALFIGWAGASLCIIGGVIFC 178

Query: 185 FS 186
           FS
Sbjct: 179 FS 180


>gi|124107616 claudin 23 [Homo sapiens]
          Length = 292

 Score = 54.3 bits (129), Expect = 9e-08
 Identities = 55/184 (29%), Positives = 83/184 (45%), Gaps = 23/184 (12%)

Query: 13  GLLLSLLGWVCSCVTTILPQWKTLNLELNE---METWIMGIWEVCVDREEVATVCKAFES 69
           G++L+  G + +   T+ P W+ +   LN+   +E +  G+W++C ++      C   + 
Sbjct: 10  GMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVELY-QGLWDMCREQSSRERECGQTDQ 68

Query: 70  FLSLP-QELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTLEAS 128
           +     Q + VAR LMV S    +LGLLL S G  C+Q     +V     GL G  L   
Sbjct: 69  WGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQ-DEPNFVL---AGLSGVVLFV- 123

Query: 129 ASATTLLPVSWVAHATIQDFWDDSIPDIIP------RWEFGGALYLGWAAGIFLALGGLL 182
           A    L+PVSW  H     F  D   D++P        +   +L LG+     L LGG  
Sbjct: 124 AGLLGLIPVSWYNH-----FLGDR--DVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGFS 176

Query: 183 LIFS 186
           L  S
Sbjct: 177 LALS 180


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.141    0.470 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,130,847
Number of Sequences: 37866
Number of extensions: 382551
Number of successful extensions: 1124
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1021
Number of HSP's gapped (non-prelim): 44
length of query: 229
length of database: 18,247,518
effective HSP length: 99
effective length of query: 130
effective length of database: 14,498,784
effective search space: 1884841920
effective search space used: 1884841920
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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