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Search of human proteins with 157738639
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157738639 tensin 4 [Homo sapiens]
(715 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157738639 tensin 4 [Homo sapiens] 1447 0.0
gi|65288071 tensin 3 [Homo sapiens] 319 6e-87
gi|66529407 tensin [Homo sapiens] 317 2e-86
gi|38787970 tensin like C1 domain containing phosphatase isoform... 301 1e-81
gi|38787957 tensin like C1 domain containing phosphatase isoform... 301 1e-81
gi|38787941 tensin like C1 domain containing phosphatase isoform... 301 1e-81
gi|55750053 atrophin-1 [Homo sapiens] 52 2e-06
gi|55750041 atrophin-1 [Homo sapiens] 52 2e-06
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi... 51 3e-06
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 50 6e-06
gi|91982772 mucin 17 [Homo sapiens] 48 4e-05
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 47 6e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 47 8e-05
gi|211971072 FERM and PDZ domain containing 4 [Homo sapiens] 46 1e-04
gi|153792074 proline rich 12 [Homo sapiens] 45 3e-04
gi|171543895 ataxin 2 [Homo sapiens] 44 4e-04
gi|117938254 BCL2-associated transcription factor 1 isoform 3 [H... 44 4e-04
gi|187475373 c-src tyrosine kinase [Homo sapiens] 44 5e-04
gi|4758078 c-src tyrosine kinase [Homo sapiens] 44 5e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 44 5e-04
gi|28559039 mediator complex subunit 1 [Homo sapiens] 44 5e-04
gi|5174545 myocyte enhancer factor 2D [Homo sapiens] 43 9e-04
gi|68989256 ras inhibitor RIN1 [Homo sapiens] 43 0.001
gi|195976771 cytokine-inducible SH2-containing protein isoform 1... 43 0.001
gi|110431352 transducer of regulated CREB protein 3 isoform b [H... 43 0.001
gi|110431354 transducer of regulated CREB protein 3 isoform a [H... 43 0.001
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 42 0.002
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 42 0.002
gi|14149916 Src-like-adaptor 2 isoform a [Homo sapiens] 42 0.003
gi|54860079 nadrin isoform 1 [Homo sapiens] 41 0.003
>gi|157738639 tensin 4 [Homo sapiens]
Length = 715
Score = 1447 bits (3745), Expect = 0.0
Identities = 715/715 (100%), Positives = 715/715 (100%)
Query: 1 MSQVMSSPLLAGGHAVSLAPCDEPRRTLHPAPSPSLPPQCSYYTTEGWGAQALMAPVPCM 60
MSQVMSSPLLAGGHAVSLAPCDEPRRTLHPAPSPSLPPQCSYYTTEGWGAQALMAPVPCM
Sbjct: 1 MSQVMSSPLLAGGHAVSLAPCDEPRRTLHPAPSPSLPPQCSYYTTEGWGAQALMAPVPCM 60
Query: 61 GPPGRLQQAPQVEAKATCFLPSPGEKALGTPEDLDSYIDFSLESLNQMILELDPTFQLLP 120
GPPGRLQQAPQVEAKATCFLPSPGEKALGTPEDLDSYIDFSLESLNQMILELDPTFQLLP
Sbjct: 61 GPPGRLQQAPQVEAKATCFLPSPGEKALGTPEDLDSYIDFSLESLNQMILELDPTFQLLP 120
Query: 121 PGTGGSQAELAQSTMSMRKKEESEALDIKYIEVTSARSRCHDGPQHCSSPSVTPPFGSLR 180
PGTGGSQAELAQSTMSMRKKEESEALDIKYIEVTSARSRCHDGPQHCSSPSVTPPFGSLR
Sbjct: 121 PGTGGSQAELAQSTMSMRKKEESEALDIKYIEVTSARSRCHDGPQHCSSPSVTPPFGSLR 180
Query: 181 SGGLLLSRDVPRETRSSSESLIFSGNQGRGHQRPLPPSEGLSPRPPNSPSISIPCMGSKA 240
SGGLLLSRDVPRETRSSSESLIFSGNQGRGHQRPLPPSEGLSPRPPNSPSISIPCMGSKA
Sbjct: 181 SGGLLLSRDVPRETRSSSESLIFSGNQGRGHQRPLPPSEGLSPRPPNSPSISIPCMGSKA 240
Query: 241 SSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSH 300
SSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSH
Sbjct: 241 SSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSH 300
Query: 301 QSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTMGQPRTPHSPPLAKEHASS 360
QSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTMGQPRTPHSPPLAKEHASS
Sbjct: 301 QSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTMGQPRTPHSPPLAKEHASS 360
Query: 361 CPPSITNSMVDIPIVLINGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPATRSNSQTLS 420
CPPSITNSMVDIPIVLINGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPATRSNSQTLS
Sbjct: 361 CPPSITNSMVDIPIVLINGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPATRSNSQTLS 420
Query: 421 DAPFTTCPEGPARDMQPTMKFVMDTSKYWFKPNITREQAIELLRKEEPGAFVIRDSSSYR 480
DAPFTTCPEGPARDMQPTMKFVMDTSKYWFKPNITREQAIELLRKEEPGAFVIRDSSSYR
Sbjct: 421 DAPFTTCPEGPARDMQPTMKFVMDTSKYWFKPNITREQAIELLRKEEPGAFVIRDSSSYR 480
Query: 481 GSFGLALKVQEVPASAQSRPGEDSNDLIRHFLIESSAKGVHLKGADEEPYFGSLSAFVCQ 540
GSFGLALKVQEVPASAQSRPGEDSNDLIRHFLIESSAKGVHLKGADEEPYFGSLSAFVCQ
Sbjct: 481 GSFGLALKVQEVPASAQSRPGEDSNDLIRHFLIESSAKGVHLKGADEEPYFGSLSAFVCQ 540
Query: 541 HSIMALALPCKLTIPQRELGGADGASDSTDSPASCQKKSAGCHTLYLSSVSVETLTGALA 600
HSIMALALPCKLTIPQRELGGADGASDSTDSPASCQKKSAGCHTLYLSSVSVETLTGALA
Sbjct: 541 HSIMALALPCKLTIPQRELGGADGASDSTDSPASCQKKSAGCHTLYLSSVSVETLTGALA 600
Query: 601 VQKAISTTFERDILPTPTVVHFKVTEQGITLTDVQRKVFFRRHYPLTTLRFCGMDPEQRK 660
VQKAISTTFERDILPTPTVVHFKVTEQGITLTDVQRKVFFRRHYPLTTLRFCGMDPEQRK
Sbjct: 601 VQKAISTTFERDILPTPTVVHFKVTEQGITLTDVQRKVFFRRHYPLTTLRFCGMDPEQRK 660
Query: 661 WQKYCKPSWIFGFVAKSQTEPQENVCHLFAEYDMVQPASQVIGLVTALLQDAERM 715
WQKYCKPSWIFGFVAKSQTEPQENVCHLFAEYDMVQPASQVIGLVTALLQDAERM
Sbjct: 661 WQKYCKPSWIFGFVAKSQTEPQENVCHLFAEYDMVQPASQVIGLVTALLQDAERM 715
>gi|65288071 tensin 3 [Homo sapiens]
Length = 1445
Score = 319 bits (817), Expect = 6e-87
Identities = 269/848 (31%), Positives = 375/848 (44%), Gaps = 160/848 (18%)
Query: 14 HAVSLAPCDEPRRTLH-PAPSPSL---PPQCSYYTTEGWGAQALMAPVPCMGPPGRLQQA 69
H S AP E R PA +P L P+ T G ++ + GP Q
Sbjct: 599 HQYSFAPDGEARLVSRCPADNPGLVQAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPDTQQ 658
Query: 70 PQVEAKATCFLPS-PGEKALG----------TPEDLDSYIDFSLESLNQMILELDPTFQL 118
P + + F P PG++ + +P ID S+E LN++ILELDPTF+
Sbjct: 659 P---SPSKAFKPRFPGDQVVNGAGPELSTGPSPGSPTLDIDQSIEQLNRLILELDPTFEP 715
Query: 119 LP-----------------------------PGTG-------GSQAELAQSTMSMRKKEE 142
+P P TG G Q A+ + R ++
Sbjct: 716 IPTHMNALGSQANGSVSPDSVGGGLRASSRLPDTGEGPSRATGRQGSSAEQPLGGRLRKL 775
Query: 143 SEALDIKYIEVTSARSRCHDGPQHCSSPSVTPPFGSLRSGGLLLSRDVPRETRSSSESLI 202
S S+C G PPF S ++ P++ + I
Sbjct: 776 SLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPPFPSPADVKETMTPGYPQDL-DIIDGRI 834
Query: 203 FSGNQGRGHQRPLPPS------EGLSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPRL 256
S + P S + PP SP P + S AS G P L
Sbjct: 835 LSSKESMCSTPAFPVSPETPYVKTALRHPPFSPPE--PPLSSPASQHKGGREPRSCPETL 892
Query: 257 EKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSHQ--SSSRSLES----- 309
+G G + ++L A S S+ + S SSN Q SS S E
Sbjct: 893 THAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVES 952
Query: 310 -------------PANSSSSLHSLGS-----VSLCTRPSDFQAP-RNPTLTMGQPRTPHS 350
P S S G+ V C PS+ QAP + L++ +P +
Sbjct: 953 SPKPMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLA 1012
Query: 351 PP--------------------------LAKEHASSCPPSIT------------------ 366
PP LA H +S PSI
Sbjct: 1013 PPSSQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTATGAADNGFLSHNFLT 1072
Query: 367 ----NSMVDIPIVLINGCPEPGSSP-PQRTPGHQNSVQPGAASPSNPCPATRSNSQTLSD 421
+S P + G PG P P++ + G+ SPS+ ++ + T+S
Sbjct: 1073 VAPGHSSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTIS- 1131
Query: 422 APF--------------TTCPEGPARDMQPTMKFVMDTSKYWFKPNITREQAIELLRKEE 467
PF + P+ P D +KFV DTSK+W+K +I+REQAI +L+ +E
Sbjct: 1132 IPFPNVLPDFSKASEAASPLPDSPG-DKLVIVKFVQDTSKFWYKADISREQAIAMLKDKE 1190
Query: 468 PGAFVIRDSSSYRGSFGLALKVQEVPASA---QSRPGEDSNDLIRHFLIESSAKGVHLKG 524
PG+F++RDS S+RG++GLA+KV P S + G+ +N+L+RHFLIE + KGV LKG
Sbjct: 1191 PGSFIVRDSHSFRGAYGLAMKVATPPPSVLQLNKKAGDLANELVRHFLIECTPKGVRLKG 1250
Query: 525 ADEEPYFGSLSAFVCQHSIMALALPCKLTIPQR---ELGGADGASDSTDSPASCQKKSAG 581
EPYFGSL+A VCQHSI LALPCKL IP+R E + +S A K+ A
Sbjct: 1251 CSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAESSPQTAANSAAELLKQGAA 1310
Query: 582 CHTLYLSSVSVETLTGALAVQKAISTTFERDILPTPTVVHFKVTEQGITLTDVQRKVFFR 641
C+ YL+SV +E+LTG A+QKA+S T ++ P TVVHFKV+ QGITLTD QRK+FFR
Sbjct: 1311 CNVWYLNSVEMESLTGHQAIQKALSITLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFR 1370
Query: 642 RHYPLTTLRFCGMDPEQRKWQKYCKPSWIFGFVAKSQTEPQENVCHLFAEYDMVQPASQV 701
RHYP+ ++ FC +DP+ RKW K S +FGFVA+ Q +NVCHLFAE+D QPAS +
Sbjct: 1371 RHYPVNSVIFCALDPQDRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAI 1430
Query: 702 IGLVTALL 709
+ V+ ++
Sbjct: 1431 VNFVSKVM 1438
>gi|66529407 tensin [Homo sapiens]
Length = 1735
Score = 317 bits (813), Expect = 2e-86
Identities = 209/501 (41%), Positives = 281/501 (56%), Gaps = 50/501 (9%)
Query: 226 PNSPSISIPCMGSKASSPHGLGSPLVASP---RLEKRLGGLAPQRGSRISVLSASPVSDV 282
P SPS+ + + GL S +ASP L + LGG SV+ SP D
Sbjct: 1267 PGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSG-------SVVPGSPCLDR 1319
Query: 283 SYMFGS-SQSLLHSSNSSHQSSSRSLESPANSS---SSLHSLGSVSLCTRPSDFQAPRNP 338
+G S S QSS+ ++P+ S S + G S T PS P +
Sbjct: 1320 HVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPS----PDSA 1375
Query: 339 TLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPGSSPPQRTPGHQNSV 398
G P TP P + S+ N ING SSP V
Sbjct: 1376 AFRQGSP-TPALPEKRRMSVGDRAGSLPN------YATING---KVSSP----------V 1415
Query: 399 QPGAASPSNPCPATRSNSQTLSDAPFTTCPEGPARDMQPTMKFVMDTSKYWFKPNITREQ 458
G +SPS +T S S TL D + P+ + + + +KFV DTSKYW+KP I+REQ
Sbjct: 1416 ASGMSSPSGG--STVSFSHTLPDFSKYSMPDN-SPETRAKVKFVQDTSKYWYKPEISREQ 1472
Query: 459 AIELLRKEEPGAFVIRDSSSYRGSFGLALKVQEVPASA--QSRPGEDSNDLIRHFLIESS 516
AI LL+ +EPGAF+IRDS S+RG++GLA+KV P + Q++ G+ +++L+RHFLIE+
Sbjct: 1473 AIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTHELVRHFLIETG 1532
Query: 517 AKGVHLKGADEEPYFGSLSAFVCQHSIMALALPCKLTIPQRELGGADGASDST---DSPA 573
+GV LKG EP FGSLSA V QHSI+ LALPCKL IP R+ D + DS+ +S A
Sbjct: 1533 PRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRD--PTDESKDSSGPANSTA 1590
Query: 574 SCQKKSAGCHTLYLSSVSVETLTGALAVQKAISTTFERDILPTPTVVHFKVTEQGITLTD 633
K+ A C+ L+++SV +E+LTG A+ KA S T D P T+VHFKV+ QGITLTD
Sbjct: 1591 DLLKQGAACNVLFVNSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTD 1650
Query: 634 VQRKVFFRRHYPLTTLRFCGMDPEQRKWQKY--CKPSWIFGFVAKSQTEPQENVCHLFAE 691
QRK+FFRRHYPL T+ FC +DP++RKW K P+ +FGFVA+ Q +N CHLFAE
Sbjct: 1651 NQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAE 1710
Query: 692 YDMVQPASQVIGLVTALLQDA 712
D QPAS ++ V+ ++ +A
Sbjct: 1711 LDPNQPASAIVNFVSKVMLNA 1731
>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
[Homo sapiens]
Length = 1285
Score = 301 bits (771), Expect = 1e-81
Identities = 195/492 (39%), Positives = 262/492 (53%), Gaps = 38/492 (7%)
Query: 238 SKASSPHGLGSPLVASPRLEKRLGGLAPQ--RGSRISVLSASPVSDVSYMFGSSQSLLHS 295
S S+P SP A P + + G AP+ GS L+ SPVS
Sbjct: 807 SPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPT----------FPP 856
Query: 296 SNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTM-GQPRTPHSPPLA 354
S+ S RS ++ +S + + R + +Q PR P + G P TP +
Sbjct: 857 SSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMP 916
Query: 355 KEHASSCPPSITNSMVDIPIVL---INGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPA 411
AS PP + + P+ NG +P + PG QPG P
Sbjct: 917 WLVASPEPPQSSPTPA-FPLAASYDTNGLSQPPLPEKRHLPGPGQ--QPGPWGPEQASSP 973
Query: 412 TRSNSQTLSDAPFTT-----CPEGPARDMQPTMKFVMDTSKYWFKPNITREQAIELLRKE 466
R S ++ AP + PE P ++ Q +KFV DTSK+W+KP+++R+QAI LL+ +
Sbjct: 974 ARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDK 1033
Query: 467 EPGAFVIRDSSSYRGSFGLALKVQEVPASAQSRPGEDSNDLIRHFLIESSAKGVHLKGAD 526
+PGAF+IRDS S++G++GLALKV P SAQ G+ L+RHFLIE+ KGV +KG
Sbjct: 1034 DPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCP 1093
Query: 527 EEPYFGSLSAFVCQHSIMALALPCKLTIPQRELGGADGASDSTDSP--------ASCQKK 578
EPYFGSLSA V QHSI ++LPC L IP + D ++ ++P A ++
Sbjct: 1094 SEPYFGSLSALVSQHSISPISLPCCLRIPSK-----DPLEETPEAPVPTNMSTAADLLRQ 1148
Query: 579 SAGCHTLYLSSVSVETLTGALAVQKAISTTFERDILPTPTVVHFKVTEQGITLTDVQRKV 638
A C LYL+SV E+LTG AV +A S PTP VVHFKV+ QGITLTD QRK+
Sbjct: 1149 GAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKL 1208
Query: 639 FFRRHYPLTTLRFCGMDPEQRKW-QKYCKPSWIFGFVAKSQTEPQENVCHLFAEYDMVQP 697
FFRRHYP+ ++ F DP+ R+W S IFGFVAK P ENVCHLFAE D QP
Sbjct: 1209 FFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQP 1268
Query: 698 ASQVIGLVTALL 709
A ++ +T +L
Sbjct: 1269 AGAIVTFITKVL 1280
>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
[Homo sapiens]
Length = 1409
Score = 301 bits (771), Expect = 1e-81
Identities = 195/492 (39%), Positives = 262/492 (53%), Gaps = 38/492 (7%)
Query: 238 SKASSPHGLGSPLVASPRLEKRLGGLAPQ--RGSRISVLSASPVSDVSYMFGSSQSLLHS 295
S S+P SP A P + + G AP+ GS L+ SPVS
Sbjct: 931 SPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPT----------FPP 980
Query: 296 SNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTM-GQPRTPHSPPLA 354
S+ S RS ++ +S + + R + +Q PR P + G P TP +
Sbjct: 981 SSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMP 1040
Query: 355 KEHASSCPPSITNSMVDIPIVL---INGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPA 411
AS PP + + P+ NG +P + PG QPG P
Sbjct: 1041 WLVASPEPPQSSPTPA-FPLAASYDTNGLSQPPLPEKRHLPGPGQ--QPGPWGPEQASSP 1097
Query: 412 TRSNSQTLSDAPFTT-----CPEGPARDMQPTMKFVMDTSKYWFKPNITREQAIELLRKE 466
R S ++ AP + PE P ++ Q +KFV DTSK+W+KP+++R+QAI LL+ +
Sbjct: 1098 ARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDK 1157
Query: 467 EPGAFVIRDSSSYRGSFGLALKVQEVPASAQSRPGEDSNDLIRHFLIESSAKGVHLKGAD 526
+PGAF+IRDS S++G++GLALKV P SAQ G+ L+RHFLIE+ KGV +KG
Sbjct: 1158 DPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCP 1217
Query: 527 EEPYFGSLSAFVCQHSIMALALPCKLTIPQRELGGADGASDSTDSP--------ASCQKK 578
EPYFGSLSA V QHSI ++LPC L IP + D ++ ++P A ++
Sbjct: 1218 SEPYFGSLSALVSQHSISPISLPCCLRIPSK-----DPLEETPEAPVPTNMSTAADLLRQ 1272
Query: 579 SAGCHTLYLSSVSVETLTGALAVQKAISTTFERDILPTPTVVHFKVTEQGITLTDVQRKV 638
A C LYL+SV E+LTG AV +A S PTP VVHFKV+ QGITLTD QRK+
Sbjct: 1273 GAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKL 1332
Query: 639 FFRRHYPLTTLRFCGMDPEQRKW-QKYCKPSWIFGFVAKSQTEPQENVCHLFAEYDMVQP 697
FFRRHYP+ ++ F DP+ R+W S IFGFVAK P ENVCHLFAE D QP
Sbjct: 1333 FFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQP 1392
Query: 698 ASQVIGLVTALL 709
A ++ +T +L
Sbjct: 1393 AGAIVTFITKVL 1404
>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
[Homo sapiens]
Length = 1419
Score = 301 bits (771), Expect = 1e-81
Identities = 195/492 (39%), Positives = 262/492 (53%), Gaps = 38/492 (7%)
Query: 238 SKASSPHGLGSPLVASPRLEKRLGGLAPQ--RGSRISVLSASPVSDVSYMFGSSQSLLHS 295
S S+P SP A P + + G AP+ GS L+ SPVS
Sbjct: 941 SPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPT----------FPP 990
Query: 296 SNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTM-GQPRTPHSPPLA 354
S+ S RS ++ +S + + R + +Q PR P + G P TP +
Sbjct: 991 SSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMP 1050
Query: 355 KEHASSCPPSITNSMVDIPIVL---INGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPA 411
AS PP + + P+ NG +P + PG QPG P
Sbjct: 1051 WLVASPEPPQSSPTPA-FPLAASYDTNGLSQPPLPEKRHLPGPGQ--QPGPWGPEQASSP 1107
Query: 412 TRSNSQTLSDAPFTT-----CPEGPARDMQPTMKFVMDTSKYWFKPNITREQAIELLRKE 466
R S ++ AP + PE P ++ Q +KFV DTSK+W+KP+++R+QAI LL+ +
Sbjct: 1108 ARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDK 1167
Query: 467 EPGAFVIRDSSSYRGSFGLALKVQEVPASAQSRPGEDSNDLIRHFLIESSAKGVHLKGAD 526
+PGAF+IRDS S++G++GLALKV P SAQ G+ L+RHFLIE+ KGV +KG
Sbjct: 1168 DPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCP 1227
Query: 527 EEPYFGSLSAFVCQHSIMALALPCKLTIPQRELGGADGASDSTDSP--------ASCQKK 578
EPYFGSLSA V QHSI ++LPC L IP + D ++ ++P A ++
Sbjct: 1228 SEPYFGSLSALVSQHSISPISLPCCLRIPSK-----DPLEETPEAPVPTNMSTAADLLRQ 1282
Query: 579 SAGCHTLYLSSVSVETLTGALAVQKAISTTFERDILPTPTVVHFKVTEQGITLTDVQRKV 638
A C LYL+SV E+LTG AV +A S PTP VVHFKV+ QGITLTD QRK+
Sbjct: 1283 GAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKL 1342
Query: 639 FFRRHYPLTTLRFCGMDPEQRKW-QKYCKPSWIFGFVAKSQTEPQENVCHLFAEYDMVQP 697
FFRRHYP+ ++ F DP+ R+W S IFGFVAK P ENVCHLFAE D QP
Sbjct: 1343 FFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQP 1402
Query: 698 ASQVIGLVTALL 709
A ++ +T +L
Sbjct: 1403 AGAIVTFITKVL 1414
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 52.0 bits (123), Expect = 2e-06
Identities = 61/238 (25%), Positives = 89/238 (37%), Gaps = 49/238 (20%)
Query: 215 LPPSEGLSPRPPNSPSISIPCMGSKA-----SSPHGLGSPLVASPRLEKRLGGLAPQRGS 269
LPP L RP N+ S S P +G++ SPH +G + P ++ LAP S
Sbjct: 301 LPPPPAL--RPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS 358
Query: 270 RISVLSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSL-------GS 322
S++P + + + SS S +++SS SSS S SP +S +L S S
Sbjct: 359 LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS-ASPFPASQALPSYPHSFPPPTS 417
Query: 323 VSLCTRPSDFQAPRNPTLTMGQPRTPHSPPLAK------EHASSCPPSITNSMVDIPIVL 376
+S+ +P + P P+ + P PP + H PPS P V
Sbjct: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVS 477
Query: 377 I----------------------------NGCPEPGSSPPQRTPGHQNSVQPGAASPS 406
+G P PG+ P G + P A SPS
Sbjct: 478 THHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPS 535
Score = 35.0 bits (79), Expect = 0.24
Identities = 60/266 (22%), Positives = 92/266 (34%), Gaps = 43/266 (16%)
Query: 191 PRETRSSSESLIFSGNQGRGHQRPLPPSEGLSPRP----------PNSPSISIPCMGSKA 240
P E SS + ++ + G RP PP P P PN P +S S +
Sbjct: 518 PLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVS---SSSNS 574
Query: 241 SSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSH 300
SS GS + P +P +G + + PV V+ + +++ + SS
Sbjct: 575 SSSTSQGSYPCSHP---------SPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSP 625
Query: 301 QS-SSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTMGQPRTPHSPPLAKEHAS 359
+ S P S G+ T P ++ P+ G P +
Sbjct: 626 AGYKTASPPGPPPYGKRAPSPGAYKTAT-PPGYKPGSPPSFRTGTP---------PGYRG 675
Query: 360 SCPPSITNSMVDIPIVLINGCPEPGSSP-PQRTPGHQNSVQPGAASPSN--PCPATRSNS 416
+ PP+ P G P G P P P S+ P A+P++ P AT+
Sbjct: 676 TSPPA-------GPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQ 728
Query: 417 QTLSDAPFTTCPEGPARDMQPTMKFV 442
+ + P PAR P K V
Sbjct: 729 EPAEEYETPESPVPPARSPSPPPKVV 754
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 52.0 bits (123), Expect = 2e-06
Identities = 61/238 (25%), Positives = 89/238 (37%), Gaps = 49/238 (20%)
Query: 215 LPPSEGLSPRPPNSPSISIPCMGSKA-----SSPHGLGSPLVASPRLEKRLGGLAPQRGS 269
LPP L RP N+ S S P +G++ SPH +G + P ++ LAP S
Sbjct: 301 LPPPPAL--RPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS 358
Query: 270 RISVLSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSL-------GS 322
S++P + + + SS S +++SS SSS S SP +S +L S S
Sbjct: 359 LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS-ASPFPASQALPSYPHSFPPPTS 417
Query: 323 VSLCTRPSDFQAPRNPTLTMGQPRTPHSPPLAK------EHASSCPPSITNSMVDIPIVL 376
+S+ +P + P P+ + P PP + H PPS P V
Sbjct: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVS 477
Query: 377 I----------------------------NGCPEPGSSPPQRTPGHQNSVQPGAASPS 406
+G P PG+ P G + P A SPS
Sbjct: 478 THHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPS 535
Score = 35.0 bits (79), Expect = 0.24
Identities = 60/266 (22%), Positives = 92/266 (34%), Gaps = 43/266 (16%)
Query: 191 PRETRSSSESLIFSGNQGRGHQRPLPPSEGLSPRP----------PNSPSISIPCMGSKA 240
P E SS + ++ + G RP PP P P PN P +S S +
Sbjct: 518 PLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVS---SSSNS 574
Query: 241 SSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSH 300
SS GS + P +P +G + + PV V+ + +++ + SS
Sbjct: 575 SSSTSQGSYPCSHP---------SPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSP 625
Query: 301 QS-SSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTMGQPRTPHSPPLAKEHAS 359
+ S P S G+ T P ++ P+ G P +
Sbjct: 626 AGYKTASPPGPPPYGKRAPSPGAYKTAT-PPGYKPGSPPSFRTGTP---------PGYRG 675
Query: 360 SCPPSITNSMVDIPIVLINGCPEPGSSP-PQRTPGHQNSVQPGAASPSN--PCPATRSNS 416
+ PP+ P G P G P P P S+ P A+P++ P AT+
Sbjct: 676 TSPPA-------GPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQ 728
Query: 417 QTLSDAPFTTCPEGPARDMQPTMKFV 442
+ + P PAR P K V
Sbjct: 729 EPAEEYETPESPVPPARSPSPPPKVV 754
>gi|239508790 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 490
Score = 51.2 bits (121), Expect = 3e-06
Identities = 82/274 (29%), Positives = 107/274 (39%), Gaps = 33/274 (12%)
Query: 168 SSPSVTPPFGSLRSGGLLLSRDV---PRETRS--SSESLIFSGNQGRGHQRPLPPSEGLS 222
S PS P SL SG L DV P + S S + SG P PPS+ S
Sbjct: 116 SPPSDVP---SLLSGVPSLPSDVSSPPSDVPSLLSDVPSLLSGVPSPPSDVPSPPSDVPS 172
Query: 223 PRPPNSPSISIPCMGSKASSPHGLGSPL--VASPRLEKRLGGLAPQRGSRISVLS--ASP 278
P P + PS+ + S P + SP V SP + L P S + +LS SP
Sbjct: 173 P-PSDVPSL----LSGVPSPPSDVPSPPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPSP 227
Query: 279 VSDVSYMFGSSQSL--LHSSNSSHQSSSRSLESPANSSSSLHSLGSV--SLCTRPSDFQA 334
SDV + SL + S S S + SP + S + S+ + + PSD
Sbjct: 228 PSDVPSLPSDVPSLSGVPSPPSDVPSLLSGVPSPPSDISPPSDVPSLLSDVPSLPSDV-- 285
Query: 335 PRNPTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPGS---SPPQRT 391
P+L G P P P S P + + DIP L++G P P S SPP
Sbjct: 286 ---PSLLSGVPSPPSDVPSLLSDVPSPPSDVPSPPSDIP--LLSGVPSPPSDVPSPPSDV 340
Query: 392 PGHQNSVQ--PGAASPSNPCPATRSNSQTLSDAP 423
P + V G SP + P SD P
Sbjct: 341 PSPPSDVPLLSGVPSPLSDVPLLSGVPSPPSDVP 374
Score = 34.3 bits (77), Expect = 0.41
Identities = 39/146 (26%), Positives = 55/146 (37%), Gaps = 20/146 (13%)
Query: 306 SLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPT---LTMGQPRTPHSPPLAKEHASSCP 362
SL SP S S H L + +P P L G P P P S P
Sbjct: 77 SLVSPQYSPVSPHC----PLVSPHYSLVSPHRPLVSPLLSGVPSPPSDVPSLLSGVPSLP 132
Query: 363 PSITNSMVDIPIV------LINGCPEPGS---SPPQRTPGHQN---SVQPGAASPSNPCP 410
+++ D+P + L++G P P S SPP P + S+ G SP + P
Sbjct: 133 SDVSSPPSDVPSLLSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPSLLSGVPSPPSDVP 192
Query: 411 ATRSN-SQTLSDAPFTTCPEGPARDM 435
+ S+ SD P + P D+
Sbjct: 193 SPPSDVPSPPSDVPLLSDVPSPPSDV 218
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 50.4 bits (119), Expect = 6e-06
Identities = 58/220 (26%), Positives = 86/220 (39%), Gaps = 21/220 (9%)
Query: 222 SPRPPNS----PSISIPCMGSKASSPHGLGSPLVASPRLEKRLG-GLAPQRGSRISVLSA 276
SP+PP+ P G + P S +K+LG ++P R R SA
Sbjct: 487 SPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSA 546
Query: 277 SPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLE-SPANSSSSLHS--------LGSVSLCT 327
S S + SS+S +S + S +S SRS S +S SS HS S S
Sbjct: 547 SSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSP 606
Query: 328 RPSDFQAPRNPTL-TMGQPRTP----HSPPLAKEHASSCPPSITNSMVDIPIVLINGCPE 382
PS +P P++ T G+P P + K PP T + +P G P
Sbjct: 607 SPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPR 666
Query: 383 PG--SSPPQRTPGHQNSVQPGAASPSNPCPATRSNSQTLS 420
P RTP + ++ + + + S S++LS
Sbjct: 667 EARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLS 706
Score = 35.0 bits (79), Expect = 0.24
Identities = 60/240 (25%), Positives = 90/240 (37%), Gaps = 47/240 (19%)
Query: 122 GTGGSQAELAQSTMSMRKKEESEALDIKYIEVTSARSRCHDGPQHCS-SPSVTPPFGSLR 180
G+G S++ S+ S S ++ + +RSR S SP+ +P S+R
Sbjct: 566 GSGSSRSRSRSSSYSSYSSRSS-----RHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIR 620
Query: 181 SGGLLLSRDVPRETRSSSESLIFSGNQGRGHQRPLPPSEGLSPRPPNSPSISIPCMGSKA 240
+ G P ++ +S+ ++P PP P PP + + P
Sbjct: 621 TKG----EPAPPPGKAGEKSV----------KKPAPP-----PAPPQATKTTAP-----V 656
Query: 241 SSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSH 300
P G P A R ++R P+R + LS S S GSS S S
Sbjct: 657 PEPTKPGDPREA--RRKERPARTPPRRRT----LSGSGSGSGSSYSGSSSR----SRSLS 706
Query: 301 QSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTMGQPRTPHSPPLAKEHASS 360
SS S+ S +SSSS HS+ S D A ++ R+P KE S
Sbjct: 707 VSSVSSVSSATSSSSSAHSVDS-------EDMYADLASPVSSASSRSPAPAQTRKEKGKS 759
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 47.8 bits (112), Expect = 4e-05
Identities = 54/218 (24%), Positives = 86/218 (39%), Gaps = 22/218 (10%)
Query: 217 PSEGLSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSA 276
P + +P +SP+ S P S P S L P S S LS
Sbjct: 3482 PVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGE--GSTPLTNMPVSTTPVASSEASTLST 3539
Query: 277 SPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPR 336
+PV +++ SSQ+ SS ++ Q ++ + +P+ SSSL ++ S S+ P
Sbjct: 3540 TPVDSNTFVTSSSQA--SSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPS 3597
Query: 337 NPTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPGSSPPQRTPGHQN 396
P++ P T + + +++ PP + I L P S+P P
Sbjct: 3598 TPSVDRSTPVTTST----QSNSTPTPPEV--------ITLPMSTPSEVSTPLTIMPVSTT 3645
Query: 397 SVQPGAASPSNPCPATRS----NSQTLSDAPFTTCPEG 430
SV A ++ P S S +S +P T PEG
Sbjct: 3646 SVTISEAGTASTLPVDTSTPVITSTQVSSSPVT--PEG 3681
Score = 37.4 bits (85), Expect = 0.049
Identities = 61/245 (24%), Positives = 90/245 (36%), Gaps = 40/245 (16%)
Query: 217 PSEGLSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSA 276
P + P ++ + S P S P + +P S L L P S S LS
Sbjct: 2598 PVDTSIPVTTSTETSSSPTTAKDTSMP--ISTPSEVSTSLTSILVSTMPVASSEASTLST 2655
Query: 277 SPVSD---VSYMFGSSQSLLHSSNSSHQSS-----SRSLESPANSSSSLHSLGSVSLCTR 328
+PV V+ G+S S + SS +S S L + S++ L + + +L T
Sbjct: 2656 TPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTT 2715
Query: 329 PSDFQAP--------RNPTLTMGQPRTPHSP-----PLAKEHASSCP------PSITNSM 369
P D P +PT G +P PL S+ P +++ +
Sbjct: 2716 PVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTA 2775
Query: 370 VDIPIVLINGCPEPGSSP--------PQRTPGHQNSVQPGAASPSNPCPATRSNSQTLSD 421
VD I + E SSP P TP ++ P + P N P S + TLS
Sbjct: 2776 VDTSIPVTTST-EASSSPTTAEVTSMPTSTPSETST--PLTSMPVNHTPVASSEAGTLST 2832
Query: 422 APFTT 426
P T
Sbjct: 2833 TPVDT 2837
Score = 36.2 bits (82), Expect = 0.11
Identities = 64/295 (21%), Positives = 104/295 (35%), Gaps = 51/295 (17%)
Query: 168 SSPSVTPPFGSLRSGGLLLSRDVPRETR--SSSESLIFSGNQGRGHQRPLPPSEGLSPRP 225
++ + P + G LL+ +P T +SSE+ S P + P
Sbjct: 2853 TAEGIVVPISTASEGSTLLT-SIPVSTTPVASSEASTLSTT----------PVDTSIPVT 2901
Query: 226 PNSPSISIPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYM 285
++ S P S P + +P S L L P GS S LS +PV + +
Sbjct: 2902 TSTEGSSSPTTAEGTSMP--ISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPV 2959
Query: 286 FGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLG----------SVSLCTRPSDFQAP 335
S+++ SS ++ + +S + +P + L S+ + +L P+D P
Sbjct: 2960 TTSAEA--SSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTP 3017
Query: 336 --------RNPTLTMGQP---RTPH--SPPLAKEHASSCPPSITNSMV--------DIPI 374
+PT G TP S PL S+ P +I + + P+
Sbjct: 3018 VTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPV 3077
Query: 375 VL---INGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPATRSNSQTLSDAPFTT 426
V ++ P P + P P + P T S TLS P T
Sbjct: 3078 VTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDT 3132
Score = 33.5 bits (75), Expect = 0.71
Identities = 45/217 (20%), Positives = 83/217 (38%), Gaps = 16/217 (7%)
Query: 218 SEGLSP---RPPNSPSISIPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVL 274
SEG++P P + ++ + +++P SP+V S + P G+ I+
Sbjct: 1804 SEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSS---SPTPAEGTSIATS 1860
Query: 275 SASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQA 334
+ S S S + + SS ++ S++ PA +S+ + + VS +D +
Sbjct: 1861 TPSEGSTALTSIPVSTTTVASSETNTLSTT-----PAVTSTPVTTYAQVSSSPTTADGSS 1915
Query: 335 PRNPTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDI--PIVLIN---GCPEPGSSPPQ 389
T G+P P ASS +++ ++ D P+ + P
Sbjct: 1916 MPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSM 1975
Query: 390 RTPGHQNSVQPGAASPSNPCPATRSNSQTLSDAPFTT 426
TP + P + P + S + TLS P T
Sbjct: 1976 PTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDT 2012
Score = 30.4 bits (67), Expect = 6.0
Identities = 64/274 (23%), Positives = 100/274 (36%), Gaps = 46/274 (16%)
Query: 164 PQHCSSPSVTPPFGSLRSG------GLLLSRDVPRETRSSSESLIFSGNQGRGHQRPLPP 217
P+ S S P S+ S G+ +R P E+R++SES
Sbjct: 79 PRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSEST---------------- 122
Query: 218 SEGLSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSAS 277
S+ + P ++ S P ++P G P+ ++P E +A S + S
Sbjct: 123 SDSTTLFPSSTEDTSSP------TTPEGTDVPM-STPSEESISSTMAFV--STAPLPSFE 173
Query: 278 PVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRP-SDFQAPR 336
+ ++Y S L + S+ SSS + S +S GS L + P S +
Sbjct: 174 AYTSLTYKVDMSTPL---TTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVAS 230
Query: 337 NPTLTM-GQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPGSSPPQRTPGHQ 395
+ +T+ P +P ASS P + L N P GS+P R P
Sbjct: 231 SEAITLLTTPVEISTPVTISAQASSSPTTAEGPS------LSNSAPSGGSTPLTRMPLSV 284
Query: 396 NSVQPGAASPSNPCPATRS----NSQTLSDAPFT 425
V AS + PA + S S +P T
Sbjct: 285 MLVVSSEASTLSTTPAATNIPVITSTEASSSPTT 318
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 47.0 bits (110), Expect = 6e-05
Identities = 55/195 (28%), Positives = 68/195 (34%), Gaps = 24/195 (12%)
Query: 228 SPSISIPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFG 287
S S S S +SS GS +K G G S S+ S S
Sbjct: 2559 SSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSS 2618
Query: 288 SSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRN---------- 337
SS S SS+SS SSS S S ++SSSS S S S + S + +
Sbjct: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSS 2678
Query: 338 --------PTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPGSSPPQ 389
P T G P A + A PS + P P+P + PPQ
Sbjct: 2679 CSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTP------APQPQAPPPQ 2732
Query: 390 RTPGHQNSVQPGAAS 404
T Q Q GA S
Sbjct: 2733 PTQPLQPKAQAGAKS 2747
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 46.6 bits (109), Expect = 8e-05
Identities = 79/331 (23%), Positives = 119/331 (35%), Gaps = 54/331 (16%)
Query: 123 TGGSQAELAQSTMSMRKKEESEALDIKYIEVTSARSRCHDGPQHC-------------SS 169
+G S +S S R+ + + ++K ++S RSR P+ SS
Sbjct: 724 SGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSS 783
Query: 170 P-----SVTPPFGSLRSGGL---LLSRDVPRETRSSSESLIFSGNQGRGHQRPLPPSEGL 221
P S TPP S RSG SR PR +RSSS PP +
Sbjct: 784 PCPKQKSQTPPRRS-RSGSSQPKAKSRTPPRRSRSSSSP---------------PPKQKS 827
Query: 222 SPRPPNSPSISIPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSD 281
S S S P K+ +P GS + SP+ ++ + PQR S +SP +
Sbjct: 828 KTPSRQSHSSSSPHPKVKSGTPPRQGS--ITSPQANEQ--SVTPQRRS---CFESSPDPE 880
Query: 282 VSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPT-- 339
+ S S SS +SS+ +SP+ SSS + ++ + R +P+
Sbjct: 881 LKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAI-ISPRQRSHSGSSSPSPS 939
Query: 340 --LTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEP-----GSSPPQRTP 392
+ PR S S P ++S P + P GS P
Sbjct: 940 RVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKV 999
Query: 393 GHQNSVQPGAASPSNPCPATRSNSQTLSDAP 423
Q P + +PCP +S + P
Sbjct: 1000 KAQTPPGPSLSGSKSPCPQEKSKDSLVQSCP 1030
Score = 41.2 bits (95), Expect = 0.003
Identities = 62/268 (23%), Positives = 95/268 (35%), Gaps = 33/268 (12%)
Query: 143 SEALDIKYIEVTSARSRCHDGPQHCSSPSVT-------PPFGSLRSGGLLLSRDVPRETR 195
S++L + T++ + H+G +P V P + L + +E R
Sbjct: 2472 SQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERR 2531
Query: 196 SSSESLIFSGNQGRGHQRPLPPSEGLSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPR 255
SSS S S S +S S S GS +S G P+
Sbjct: 2532 SSSSS----------------SSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVA 2575
Query: 256 LEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSS 315
L++ + + P SS S SS+SS SSS S S ++SSS
Sbjct: 2576 LKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2635
Query: 316 SLHSLGSVSLCTRPSDFQAPRNP-TLTMGQPRTPHSPPLAKEHASSCPPSI-----TNSM 369
S S S S + PS P P + +P +P PP + + S I + S+
Sbjct: 2636 SSSSSSSSSSSSSPS----PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSL 2691
Query: 370 VDIPIVLINGCPEPGSSPPQRTPGHQNS 397
P+ P+P Q + + S
Sbjct: 2692 SYSPVERRRPSPQPSPRDQQSSSSERGS 2719
Score = 38.1 bits (87), Expect = 0.029
Identities = 44/165 (26%), Positives = 59/165 (35%), Gaps = 12/165 (7%)
Query: 265 PQR----GSRISVLSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSL--- 317
PQR GS + S S SS + S SS +S RSL SP + + S
Sbjct: 718 PQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRS--RSLSSPRSKAKSRLSL 775
Query: 318 -HSLGSVSLCTRPSDFQAPRNPTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVL 376
SL S C + PR QP+ P + +SS PP S P
Sbjct: 776 RRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKT--PSRQ 833
Query: 377 INGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPATRSNSQTLSD 421
+ P TP Q S+ A+ + P RS ++ D
Sbjct: 834 SHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPD 878
Score = 37.4 bits (85), Expect = 0.049
Identities = 63/298 (21%), Positives = 109/298 (36%), Gaps = 46/298 (15%)
Query: 151 IEVTSARSRCHDGPQ-------HCSSPSVTPPFGSLRS--------GGLLLSRDVPRETR 195
+ + S+R C P C SP + P GS R+ GG ++ PR
Sbjct: 2107 VALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPD 2166
Query: 196 SSSESLIFSGNQGRGHQRPLPPSEGLSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPR 255
S+ + Q R S G + PP+ + + S+ +P L S A
Sbjct: 2167 HQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAP-- 2224
Query: 256 LEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSS 315
A SRI SA+ ++ S + + ++ ++S +++ ++ + ++
Sbjct: 2225 --------AANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTA 2276
Query: 316 SLHSLGSVSLCTRPSDFQAPRNPTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIV 375
S +V+L +D + P P + + RTP + S PP+ N
Sbjct: 2277 VAPS--AVNL----ADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAAN-------- 2322
Query: 376 LINGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPATRS-NSQTLSDAPFTTCPEGPA 432
P SS + P N V P +A + P S + L+ A T+ PA
Sbjct: 2323 ------YPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPA 2374
Score = 36.2 bits (82), Expect = 0.11
Identities = 78/357 (21%), Positives = 123/357 (34%), Gaps = 37/357 (10%)
Query: 73 EAKATCFLPSPGEKALGTPEDLDSYIDFSLESLNQMILELDPTFQLLP---PGTGGSQAE 129
E+K LP + P D + F ++ + L T + P G G S
Sbjct: 1163 ESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPET 1222
Query: 130 LAQSTMSMRKKEESEALDIKYIEVTSARSRCHDGPQHCSSPSVTPPFGSLRSGGLLLSRD 189
Q++ ++ E +++ V + H SS + S + R
Sbjct: 1223 KEQNSALPTSSQDEELMEV----VEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERP 1278
Query: 190 VPRETRSSSESL-------IFSGNQGRGHQRPLPPSEGLSPRPPNSPSISIPCMGSKASS 242
T S+S + S G P + LS P S P + + S
Sbjct: 1279 AVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSP-LEFRNSG 1337
Query: 243 PHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSHQS 302
P G S +++ L G ++ L P D+ S++S HSS+
Sbjct: 1338 PLGTEMNTGFSSEVKEDLNG------PFLNQLETDPSLDMKEQ--STRSSGHSSSELSPD 1389
Query: 303 SSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTMGQPRTP-------HSPPLAK 355
+ +N S S L +V + +P + G PRTP SP L
Sbjct: 1390 AVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRD 1449
Query: 356 EHASSCPPSITNS---MVDIPIVLINGCPEPGSSP-PQRTPGHQNSVQPGAASPSNP 408
+ S++ S M DIP G E SSP P+ P + +P + SPS+P
Sbjct: 1450 GSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALP---QTPRPRSRSPSSP 1503
Score = 31.6 bits (70), Expect = 2.7
Identities = 56/245 (22%), Positives = 84/245 (34%), Gaps = 41/245 (16%)
Query: 191 PRETRSSSESLIF-SGNQGRGHQRPLPPSEGLSPRPPNSPSISIPCMGSKASSPHGLGSP 249
P ++R +SE S G+ + L P PR P + S A + GS
Sbjct: 2414 PSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQ 2473
Query: 250 LVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHS------------SN 297
++S + G P SDV S+ + S S+
Sbjct: 2474 SLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSS 2533
Query: 298 SSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTMGQPRTPHSPPLAKEH 357
SS SSS S S ++SSSS S GS S + S P P + + R P P KE
Sbjct: 2534 SSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSL--PVQPEVAL--KRVPSPTPAPKEA 2589
Query: 358 ASSCPPSITNSMVDIPIVLINGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPATRSNSQ 417
PP+ TP + ++S S+ ++ S+S
Sbjct: 2590 VRE------------------------GRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSS 2625
Query: 418 TLSDA 422
+ S +
Sbjct: 2626 SSSSS 2630
>gi|211971072 FERM and PDZ domain containing 4 [Homo sapiens]
Length = 1322
Score = 45.8 bits (107), Expect = 1e-04
Identities = 69/278 (24%), Positives = 109/278 (39%), Gaps = 39/278 (14%)
Query: 87 ALGTPEDLDSYIDFSLESLNQMILELDPTFQLLPPGTGGSQAELAQSTMSMRKKEESEAL 146
+L PE D+ DF L SLN I P F+ + + +Q+ KE+ +L
Sbjct: 785 SLPPPEGDDNEDDFLLRSLNMAIAAPPPGFR----DSSDEEDSQSQAASFPEDKEKGSSL 840
Query: 147 DIKYIEV-------TSARSRCHDGPQHCSSPSVTPPFGSLRSGGLLLSRDVPRETRS--- 196
I V TSA +C G + +V G+L + L +S + S
Sbjct: 841 QNDEIPVSLIDAVPTSAEGKCEKGLDN----AVVSTLGALEA--LSVSEEQQTSDNSGVA 894
Query: 197 -----SSESLIFSGNQGRGHQRPLPPSEGLSPRPPNSPSISIPCMGSKASSPHGLGSPLV 251
S ES SGN+ + + S L+ S ++S + + H L
Sbjct: 895 ILRAYSPESSSDSGNETNSSE--MTESSELATAQKQSENLSRMFLATHEGY-HPLAEEQT 951
Query: 252 ASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPA 311
P + GGL P+ L+A P +D+ S+ LLHS + + + +S
Sbjct: 952 EFPASKTPAGGLPPKSSH---ALAARPATDLPPKVVPSKQLLHSDHMEMEPETMETKSVT 1008
Query: 312 NSSSSLHSLGSVSL-CTRPSDFQAPRNPTLTMGQPRTP 348
+ S LH +GSV+ CT + R L G+ + P
Sbjct: 1009 DYFSKLH-MGSVAYSCT------SKRKSKLADGEGKAP 1039
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 44.7 bits (104), Expect = 3e-04
Identities = 51/205 (24%), Positives = 79/205 (38%), Gaps = 42/205 (20%)
Query: 214 PLPPSEGLSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISV 273
P P+ GL P+PP +P++ P S GLG L A+ + LG P R+
Sbjct: 1315 PSVPARGLQPQPPATPAVPHP----PPSGAFGLGGALEAAE--SEGLGLGCPSPCKRLD- 1367
Query: 274 LSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQ 333
+ + ++L S+ S +++ + + SS++ +L L
Sbjct: 1368 ---------EELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLA------- 1411
Query: 334 APRNPTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPE--------PGS 385
P++ + TP PPLA A PP + +P NG PE P +
Sbjct: 1412 GPKDTS-------TPDGPPLAPAAAVPGPPPLPG----LPSANSNGTPEPPLLEEKPPPT 1460
Query: 386 SPPQRTPGHQNSVQPGAASPSNPCP 410
PP TP Q P P+ P P
Sbjct: 1461 PPPAPTPQPQPPPPPPPPQPALPSP 1485
>gi|171543895 ataxin 2 [Homo sapiens]
Length = 1313
Score = 44.3 bits (103), Expect = 4e-04
Identities = 37/111 (33%), Positives = 48/111 (43%), Gaps = 23/111 (20%)
Query: 342 MGQPRTPHSPPLAKEHASSCPPS------ITNSMVDIPIVLINGCPEPGSSPPQRTPGHQ 395
MGQP + P + H S P+ + N V P + CP P S PP R
Sbjct: 516 MGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWP----SPCPSPSSRPPSRYQSGP 571
Query: 396 NSVQPGAASPSNP--CPATRSN------SQTLSDAPFTTCP-----EGPAR 433
NS+ P AA+P+ P P +R + S S AP +T P EGP R
Sbjct: 572 NSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPR 622
Score = 40.8 bits (94), Expect = 0.004
Identities = 79/333 (23%), Positives = 120/333 (36%), Gaps = 64/333 (19%)
Query: 215 LPPSEGLSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGS----- 269
LPP RPP+ P S P S HG +P+ P KR+ P R S
Sbjct: 574 LPPRAATPTRPPSRPP-SRPSRPPSHPSAHGSPAPVSTMP---KRMSSEGPPRMSPKAQR 629
Query: 270 -----RISVLSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGSVS 324
R+S S S + ++ H+ S + + SP+ + S G
Sbjct: 630 HPRNHRVSAGRGSISSGLEFVS-------HNPPSEAATPPVARTSPSGGTWSSVVSGVPR 682
Query: 325 LCTRPSDFQAPRNPTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPG 384
L + ++PR ++ TP P LA A P V +PI P
Sbjct: 683 LSPKTHRPRSPRQNSIG----NTPSGPVLASPQAGIIP----TEAVAMPI--------PA 726
Query: 385 SSPPQRTPGHQNSVQPGAASPSNPCPATRSNSQTLSDAPFTTCPEGPARDMQP--TMKFV 442
+SP +P +V P + + + R NS P G +++P T
Sbjct: 727 ASPTPASPASNRAVTPSSEAKDSRLQDQRQNS-----------PAGNKENIKPNETSPSF 775
Query: 443 MDTSKYWFKPNIT--REQAIELLRKEEPGAFVIRDSSSYRGSFGLALKVQEVPASAQSRP 500
P ++ R+Q +L K+ F ++ SS+ L K +R
Sbjct: 776 SKAENKGISPVVSEHRKQIDDL--KKFKNDFRLQPSSTSESMDQLLNK---------NRE 824
Query: 501 GEDSNDLIRHFLIESSAKGVHLKGADEEPYFGS 533
GE S DLI+ IE SAK ++ + GS
Sbjct: 825 GEKSRDLIKD-KIEPSAKDSFIENSSSNCTSGS 856
Score = 32.3 bits (72), Expect = 1.6
Identities = 82/381 (21%), Positives = 129/381 (33%), Gaps = 86/381 (22%)
Query: 116 FQLLPPGTGGSQAELAQSTMSMRKKEESEALDIKYIE-------VTSARSRCHDGPQHCS 168
F+L P T S +L R+ E+S L IE + ++ S C G +
Sbjct: 804 FRLQPSSTSESMDQLLNKN---REGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPN 860
Query: 169 SPSVTPPFGS---------LRSGGLLLS--------------RDVPRETRSSSESLIFSG 205
SPS++P S + S G+ S +D + R S+ +
Sbjct: 861 SPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKE 920
Query: 206 NQGRGHQRPLPPSEGLSPRPPNSPSISI-------PCMGSKASSPHGLGSPLVASPRLEK 258
R +P P + SPRP PS S+ P + P+ SP ++
Sbjct: 921 FNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQP 980
Query: 259 RLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLH 318
L P + + V A V M Q H S H +S+ P ++ +
Sbjct: 981 ----LYPIPMTPMPVNQAKTYRAVPNMPQQRQDQHHQSAMMHPASAAG--PPIAATPPAY 1034
Query: 319 SLGSVSLCTRPSDFQAPRNPTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLIN 378
S V+ +P QP H P +H P I
Sbjct: 1035 STQYVAY-----------SPQQFPNQPLVQHVPHYQSQHPHVYSPVI------------- 1070
Query: 379 GCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPATRSNSQTLSDAPFTTCPEGP-ARDMQP 437
G++ P H QPG S S AT+ + + A + CP+ P ++ P
Sbjct: 1071 ----QGNARMMAPPTH---AQPGLVSSS----ATQYGAHEQTHAMY-ACPKLPYNKETSP 1118
Query: 438 TMKFVMDT---SKYWFKPNIT 455
+ F + T ++ + PN T
Sbjct: 1119 SFYFAISTGSLAQQYAHPNAT 1139
>gi|117938254 BCL2-associated transcription factor 1 isoform 3 [Homo
sapiens]
Length = 747
Score = 44.3 bits (103), Expect = 4e-04
Identities = 100/411 (24%), Positives = 153/411 (37%), Gaps = 73/411 (17%)
Query: 156 ARSRCHDGPQHCSSPSVTPPFGSLRSGGLLLSRDVPRETRSSSESLIFSGNQGRGH---- 211
+RSR H + SS S + + RS + SRD R+ R++ G +GRG
Sbjct: 23 SRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQ 82
Query: 212 ----------QRPL-------PPSEGLS-PRPPNSPSISIPCMGSKA-SSPHGLGSPLVA 252
RP+ P G S R P S+S S++ S SP +
Sbjct: 83 GGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSS 142
Query: 253 SPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLE-SPA 311
S R +P S +S S G Q + S + + E P+
Sbjct: 143 SSR------SSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPS 196
Query: 312 NSSSSLHSLGSVSLCTRPSDFQAPRNPTLTMGQPRTPHSP-PLAKEHASSCPPSITNSMV 370
S + + S P A N PR+PHSP P+A PPS ++S
Sbjct: 197 ESIDEFNKSSATSGDIWPG-LSAYDN------SPRSPHSPSPIA------TPPSQSSSCS 243
Query: 371 DIPIV----LINGCPEPGSSPPQRTPGHQNS---------VQPGAASPSNPCPATRSNSQ 417
D P++ P S Q +P S P SP + P+ RS ++
Sbjct: 244 DAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAK 303
Query: 418 TLS--DAP-------FTTCPEGPARDMQPTMKFVMDTSKYWFKPNITREQAIELLRKEEP 468
T++ +AP + P+G ++ T KF+ + K RE++ R+E P
Sbjct: 304 TIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKSPPLH--KNLDAREKS--TFREESP 359
Query: 469 GAFVIRDSSSYRGSFGLALKVQEVPASAQSRPGEDSND-LIRHFLIESSAK 518
+ S S+R + LK+ VP +RP + D L+ L+ S K
Sbjct: 360 LRIKMIASDSHRPE--VKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKK 408
>gi|187475373 c-src tyrosine kinase [Homo sapiens]
Length = 450
Score = 43.9 bits (102), Expect = 5e-04
Identities = 35/119 (29%), Positives = 52/119 (43%), Gaps = 19/119 (15%)
Query: 449 WFKPNITREQAIELLRKEEPGAFVIRDSSSYRGSFGLALKVQEVPASAQSRPGEDSNDLI 508
WF ITREQA LL E G F++R+S++Y G + L + + +
Sbjct: 82 WFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCV---------------SCDGKV 126
Query: 509 RHFLIESSAKGVHLKGADEEPYFGSLSAFVCQHSIMALALPCKLTIPQRELGGADGASD 567
H+ I A + + DEE YF +L V ++ A L C I + + G A D
Sbjct: 127 EHYRIMYHASKLSI---DEEVYFENLMQLVEHYTSDADGL-CTRLIKPKVMEGTVAAQD 181
>gi|4758078 c-src tyrosine kinase [Homo sapiens]
Length = 450
Score = 43.9 bits (102), Expect = 5e-04
Identities = 35/119 (29%), Positives = 52/119 (43%), Gaps = 19/119 (15%)
Query: 449 WFKPNITREQAIELLRKEEPGAFVIRDSSSYRGSFGLALKVQEVPASAQSRPGEDSNDLI 508
WF ITREQA LL E G F++R+S++Y G + L + + +
Sbjct: 82 WFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCV---------------SCDGKV 126
Query: 509 RHFLIESSAKGVHLKGADEEPYFGSLSAFVCQHSIMALALPCKLTIPQRELGGADGASD 567
H+ I A + + DEE YF +L V ++ A L C I + + G A D
Sbjct: 127 EHYRIMYHASKLSI---DEEVYFENLMQLVEHYTSDADGL-CTRLIKPKVMEGTVAAQD 181
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 43.9 bits (102), Expect = 5e-04
Identities = 93/410 (22%), Positives = 139/410 (33%), Gaps = 63/410 (15%)
Query: 24 PRRTLHPAPSPSLPPQCSYYTTEGWGAQALMAPVPCMGPPGRLQQAPQVEAKATCFLPSP 83
P L P L + TT AP P PP L P + P
Sbjct: 534 PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593
Query: 84 GEKALGTPEDLDSYIDFSLESLNQMILELDPTFQLLPPGTGGSQ-AELAQSTMSMRKKEE 142
AL +P L L L + P L P S A S ++ +
Sbjct: 594 APPALASPP-LQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQA 652
Query: 143 SEALDIKYIEVTSARSRCHDGPQHCSSPSVTPPFGSLRSGGLLLSRDVPRETRSSSESLI 202
AL + ++ + SP V PF S + S P + S +
Sbjct: 653 PNALAVHLLQAPFSPP---------PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA-- 701
Query: 203 FSGNQGRGHQRPLPPSEGLSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPRLEKRLGG 262
PP + + P PP SP +S P +P L +P + P
Sbjct: 702 -------------PPLQ-VPPSPPASPPMS-PSATPPPQAPPPLAAPPLQVPPSPPASPP 746
Query: 263 LAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGS 322
++P SA+P V + + + S + S + P + +L +
Sbjct: 747 MSP---------SATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPL 797
Query: 323 VSLCTRPSDF--QAPRNPTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGC 380
+L + P+ F QAP +P+ ++ PP A PP + ++ +P
Sbjct: 798 QALPSPPASFPGQAPFSPSASLPMSPLATPPPQA-------PPVLAAPLLQVP------- 843
Query: 381 PEPGSSP----PQR--TPGHQNSVQPG----AASPSNPCPATRSNSQTLS 420
P P +SP P+R TPG SV A +P P P +RS S TLS
Sbjct: 844 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 893
Score = 37.7 bits (86), Expect = 0.037
Identities = 51/219 (23%), Positives = 82/219 (37%), Gaps = 31/219 (14%)
Query: 208 GRGHQRPLPPSEGLSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQR 267
G G QRP S S P +SP+ S P G+P + + + GL R
Sbjct: 231 GGGLQRPASRSLSSSATPLSSPA---------RSGPSARGTPRAPAHPSQPKPKGLQALR 281
Query: 268 GSRISVLSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSL--GSVSL 325
+++ P D + G S ++ S + +R + P N+++ L + S L
Sbjct: 282 PPQVT----PPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPL 337
Query: 326 CT-RPSDFQAPRNPTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPG 384
T P +P P P P +PP S PPS+T + P P
Sbjct: 338 ATPLPLAPPSPSAPPSLQTLPSPPATPP------SQAPPSMTTPPMQAP-------PSLQ 384
Query: 385 SSPPQRTPGHQNSVQPGAASPSNPCPATRSNSQTLSDAP 423
+ PP + P + P +P +P + + T +P
Sbjct: 385 TIPPIQVP--HSLTSPSLQAPPSPLALSSLQATTSLGSP 421
Score = 36.2 bits (82), Expect = 0.11
Identities = 76/298 (25%), Positives = 100/298 (33%), Gaps = 61/298 (20%)
Query: 182 GGLLLSRDVPRE--TRSSSESLIFSGNQ----GRGHQRPLPPSEGLSPRPPNSPSISIPC 235
GG + PR TRS+ S ++ GRG + P P++ SP P +SP
Sbjct: 66 GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAP--PAKNTSPGPVSSPG----- 118
Query: 236 MGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHS 295
S + P LG + E G A + R S LSA D S + S +
Sbjct: 119 RASGTTRPGPLGQKGLRISAEETVARGKATEAPKR-SALSAGARRDTSGPTPGTPSPAMA 177
Query: 296 SNSSHQSSSRSLESPAN---------------SSSSLHSL-------------------- 320
S + L PA SS+S HS
Sbjct: 178 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237
Query: 321 GSVSLCTRPSDFQAP-RNPTLTMGQPRTPHSP--PLAKEHASSCPPSITNSMVDIPIVLI 377
S SL + + +P R+ G PR P P P K + PP +T D L
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL- 296
Query: 378 NGCPEPGSSPPQRTPGHQNSVQPGAASPSN---PCPATRSNSQTLSDAPFTTCPEGPA 432
P SS P TP + P N P PAT S L+ P P P+
Sbjct: 297 ----GPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA-TPLPLAPPSPS 349
Score = 35.0 bits (79), Expect = 0.24
Identities = 102/452 (22%), Positives = 155/452 (34%), Gaps = 77/452 (17%)
Query: 32 PSPSLPPQC----SYYTTEGWGAQALMAPVPCMGPPGRLQQAPQVEAKATCFLPS----P 83
PSPS PP S T A M P PP LQ P ++ + PS P
Sbjct: 346 PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPS-LQTIPPIQVPHSLTSPSLQAPP 404
Query: 84 GEKALGTPEDLDSYIDFSLESLNQMILELDPTFQL----------LPPGTGGSQAELA-- 131
AL + + S +L++ + + Q PP + QA L+
Sbjct: 405 SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLP 464
Query: 132 -----QSTMSMRKKEESEALDIKYIE-VTSARSRCHDGP------------QHCSSPSVT 173
Q+++S S L I ++ ++S S P + PS+
Sbjct: 465 ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524
Query: 174 PPFGSLRSGGLL-LSRDVPRETRSSSESLIFSGNQGRGHQRPLP---PSEGLSPRPPNSP 229
P SL + L L P +++S L + P P P L+ PP +P
Sbjct: 525 TPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETP 584
Query: 230 SISIPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSS 289
S ++P P +ASP L+ GL +S L+ P +
Sbjct: 585 S--------SIATPPPQAPPALASPPLQ----GLP---SPPLSPLATPPPQAPPXLALPP 629
Query: 290 QSLLHSSNSSHQSSSRSLESP-ANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTMGQPRTP 348
S +S S + SP A ++ ++H L + QAP +P P
Sbjct: 630 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP---------P 680
Query: 349 HSPPLAKEHA--SSCPPSITNSMVDIPI-------VLINGCPEPGSSPPQRTPGHQNSVQ 399
SPP++ S PPS+ + +P + + P P + PP P Q
Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPS 740
Query: 400 PGAASPSNPCPATRSNSQTLSDAPFTTCPEGP 431
P A+ P +P L AP P P
Sbjct: 741 PPASPPMSPSATPPPRVPPLLAAPPLQVPPSP 772
Score = 35.0 bits (79), Expect = 0.24
Identities = 53/218 (24%), Positives = 75/218 (34%), Gaps = 14/218 (6%)
Query: 216 PPSEGLSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLS 275
PP +GL P PP SP + P +P L P + +P L+P +
Sbjct: 601 PPLQGL-PSPPLSPLATPP-----PQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPN 654
Query: 276 ASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAP 335
A V + F S + S +S S S + SL + L PS P
Sbjct: 655 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP---P 711
Query: 336 RNPTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPGSSPPQRTPGHQ 395
+P ++ P +PP PPS S P + + P P P P Q
Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS----PPMSPSATPPPRVPPLLAAPPLQ 767
Query: 396 NSVQPGAASPSNPCPATRSNS-QTLSDAPFTTCPEGPA 432
P A+ P +P + L+ P P PA
Sbjct: 768 VPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPA 805
Score = 30.8 bits (68), Expect = 4.6
Identities = 55/258 (21%), Positives = 90/258 (34%), Gaps = 45/258 (17%)
Query: 221 LSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVS 280
L+PRPP SP P + G+ V L +R GG+ ++ ++P +
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGA--VGRKPLAERAGGI-----GGATIPESAPRA 77
Query: 281 DVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDF-------- 332
+ G+S S + R+ + S + S G S TRP
Sbjct: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137
Query: 333 -----------QAPRNPTLTMGQPRTPHSP-PLAKEHASSCPPSITNSMVDIPIVLINGC 380
+AP+ L+ G R P P A + + V +P +
Sbjct: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 197
Query: 381 PEPGSSPPQR---TPGHQNSVQPGAASPSNPC-------PATR--SNSQTLSDAPFTT-- 426
P P + P++ + ++ +P A+ P PA+R S+S T +P +
Sbjct: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 257
Query: 427 ----CPEGPARDMQPTMK 440
P PA QP K
Sbjct: 258 SARGTPRAPAHPSQPKPK 275
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/221 (27%), Positives = 85/221 (38%), Gaps = 36/221 (16%)
Query: 217 PSEGLSPRPPNSPSIS----IPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRIS 272
PS S RP P+ + P ++ +P G+ +P + ++ G +
Sbjct: 1022 PSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKG----------T 1071
Query: 273 VLSASPVSDVSYMF-GSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSD 331
V+ P S Y GS S S+ SH SSS S S + S S GS S S
Sbjct: 1072 VMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSM 1131
Query: 332 FQA--------PRNPTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEP 383
+ + +N + + G+ P S P+ K SS S P L+N P
Sbjct: 1132 YSSQGSSGSSQSKNSSQSGGK---PGSSPITKHGLSSGSSSTKMKPQGKPSSLMN----P 1184
Query: 384 GSSPPQRTPGHQNSVQPGA----ASPSNPCPATRSNSQTLS 420
S P +P H S PG ASP P P T +S+ S
Sbjct: 1185 SLSKPNISPSH--SRPPGGSDKLASPMKPVPGTPPSSKAKS 1223
Score = 37.4 bits (85), Expect = 0.049
Identities = 60/247 (24%), Positives = 88/247 (35%), Gaps = 50/247 (20%)
Query: 126 SQAELAQSTMSMRKKEESEALDIKYIEVTSARSRCHDGPQHCSSPSVTPPFGSLRSGGLL 185
S + + ST K +SE + + S+ G + S +SGG
Sbjct: 1102 SSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSS--------QSGGKP 1153
Query: 186 LSRDVPRETRSSSESLIFSGNQGRGHQRPLPPSEGLSPRPPNSPSISIPCMGSKASSPHG 245
S + + SS S QG+ P +PS+S P + S P G
Sbjct: 1154 GSSPITKHGLSSGSSSTKMKPQGK-------------PSSLMNPSLSKPNISPSHSRPPG 1200
Query: 246 LGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSHQSSSR 305
GS +ASP + P G+ S + SP+S S SH S +
Sbjct: 1201 -GSDKLASP--------MKPVPGTPPSSKAKSPISS-------------GSGGSHMSGTS 1238
Query: 306 SLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPT------LTMGQPRTPHSPPLAKEHAS 359
S S SSS L S GS+S T PS + + +M + H K +
Sbjct: 1239 S-SSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSR 1297
Query: 360 SCPPSIT 366
+ PS+T
Sbjct: 1298 NKKPSLT 1304
>gi|5174545 myocyte enhancer factor 2D [Homo sapiens]
Length = 521
Score = 43.1 bits (100), Expect = 9e-04
Identities = 44/145 (30%), Positives = 62/145 (42%), Gaps = 11/145 (7%)
Query: 277 SPVSDVSYMFGSSQSLLHSS-----NSSHQSSSRSLES-PANSSSSLHSLGSVSLCTRPS 330
+PV V+ SQ L SS N+ +Q +S L S PA SS SLG+V+ +P
Sbjct: 309 TPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAWQQPQ 368
Query: 331 DFQAPRNPTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIV-LINGCPEPGSSPPQ 389
Q P+ P QP P P + PP + +V + + LI G P P
Sbjct: 369 QPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAAL 428
Query: 390 RTPGHQN-SVQPGAASPS---NPCP 410
H + S++ SPS +P P
Sbjct: 429 TVTTHPHISIKSEPVSPSRERSPAP 453
>gi|68989256 ras inhibitor RIN1 [Homo sapiens]
Length = 783
Score = 42.7 bits (99), Expect = 0.001
Identities = 45/173 (26%), Positives = 75/173 (43%), Gaps = 25/173 (14%)
Query: 391 TPGHQNSVQPGAASPSNPCPATRSNSQTLSDAPFTTC---------PEGPARDMQPTMKF 441
+PG + PGA SPS+ + + D + P+ P R + +
Sbjct: 3 SPGESGAGSPGAPSPSSFTTGHLAREKPAQDPLYDVPNASGGQAGGPQRPGRVVSLRERL 62
Query: 442 VMDTSKYWFKPNITREQAIELLRKEEPGAFVIRDSSSYRGSFGLALKVQEVPASAQSRPG 501
++ T W + A+ +LR E PG F++R S++ R L +++ E S P
Sbjct: 63 LL-TRPVWLQLQANAAAALHMLRTEPPGTFLVRKSNT-RQCQALCMRLPEA-----SGPS 115
Query: 502 EDSNDLIRHFLIESSAKGVHLKGADEEPYFGSLSAFVCQ--HSIMALALPCKL 552
S+ H+++ES GV L+G+ E F L +C H+ L LP +L
Sbjct: 116 FVSS----HYILESPG-GVSLEGS--ELMFPDLVQLICAYCHTRDILLLPLQL 161
>gi|195976771 cytokine-inducible SH2-containing protein isoform 1
[Homo sapiens]
Length = 275
Score = 42.7 bits (99), Expect = 0.001
Identities = 37/157 (23%), Positives = 59/157 (37%), Gaps = 14/157 (8%)
Query: 356 EHASSCPPSITNSMVDIPIVLINGCPEPGSSPPQRTPGHQNSVQPGAASPS---NPCPAT 412
EH S CP ++ +D P+ P P G + P P P PA
Sbjct: 4 EHTSHCPHHDDDTAMDTPL------PRPRPLLAVERTGQRPLWAPSLELPKPVMQPLPAG 57
Query: 413 RSNSQTLSDAPFTTCPEGPARDMQPTMKFVMDTSKY-----WFKPNITREQAIELLRKEE 467
+ P T E D + + + T Y W+ +IT +A + L+K
Sbjct: 58 AFLEEVAEGTPAQTESEPKVLDPEEDLLCIAKTFSYLRESGWYWGSITASEARQHLQKMP 117
Query: 468 PGAFVIRDSSSYRGSFGLALKVQEVPASAQSRPGEDS 504
G F++RDS+ F L++K P + + + S
Sbjct: 118 EGTFLVRDSTHPSYLFTLSVKTTRGPTNVRIEYADSS 154
>gi|110431352 transducer of regulated CREB protein 3 isoform b [Homo
sapiens]
Length = 618
Score = 42.7 bits (99), Expect = 0.001
Identities = 58/220 (26%), Positives = 92/220 (41%), Gaps = 25/220 (11%)
Query: 221 LSPRPPNSPSISIPCMGSKASSPH-GLGSPLVASPRLEK-RLGGLAPQRGSRISVLSASP 278
LS N P S+P AS+ H L +++P L L G + +R +S L+ SP
Sbjct: 342 LSSSLNNHPQTSVP----NASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSP 397
Query: 279 VSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNP 338
+ G S+ L +S + +S+ + S + S L + + + P + AP+
Sbjct: 398 GPEAHQ--GFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQV-SPPPPYPAPQEL 454
Query: 339 TLTM-GQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPGSSPPQRTPGHQNS 397
T + QPR P +P + ASS P S + L N P+ G Q S
Sbjct: 455 TQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFD--------QQS 506
Query: 398 VQPGAASPSNPCPATRSNSQTLSD------APFTTCPEGP 431
++PG A P P + S+ L D +P++ C P
Sbjct: 507 MRPGPAFPQQ-VPLVQQGSRELQDSFHLRPSPYSNCGSLP 545
>gi|110431354 transducer of regulated CREB protein 3 isoform a [Homo
sapiens]
Length = 619
Score = 42.7 bits (99), Expect = 0.001
Identities = 58/220 (26%), Positives = 92/220 (41%), Gaps = 25/220 (11%)
Query: 221 LSPRPPNSPSISIPCMGSKASSPH-GLGSPLVASPRLEK-RLGGLAPQRGSRISVLSASP 278
LS N P S+P AS+ H L +++P L L G + +R +S L+ SP
Sbjct: 342 LSSSLNNHPQTSVP----NASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSP 397
Query: 279 VSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNP 338
+ G S+ L +S + +S+ + S + S L + + + P + AP+
Sbjct: 398 GPEAHQ--GFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQV-SPPPPYPAPQEL 454
Query: 339 TLTM-GQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPGSSPPQRTPGHQNS 397
T + QPR P +P + ASS P S + L N P+ G Q S
Sbjct: 455 TQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFD--------QQS 506
Query: 398 VQPGAASPSNPCPATRSNSQTLSD------APFTTCPEGP 431
++PG A P P + S+ L D +P++ C P
Sbjct: 507 MRPGPAFPQQ-VPLVQQGSRELQDSFHLRPSPYSNCGSLP 545
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 42.4 bits (98), Expect = 0.002
Identities = 55/238 (23%), Positives = 89/238 (37%), Gaps = 34/238 (14%)
Query: 200 SLIFSGNQGRGHQRPLPPSEGLSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPRLEKR 259
S+ +S QG+ Q+ LPP++ P+P + + P + +G P A+ E+R
Sbjct: 1390 SVPYSTGQGQPQQQQLPPAQ---PQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERR 1446
Query: 260 LGGLAPQRGSRISVLSASPVSDVSYMFGSSQ-SLLHSSNSSHQSSSRSLESPANSSSSLH 318
G P + + FG + S +N+ + + P +S+ +
Sbjct: 1447 PAG--------------GPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVA 1492
Query: 319 SLGSV---------SLCTRPSDFQAPRNPTLTMGQPRTP---HSPPLAKEHASSCPPSIT 366
G++ + R S AP+ P G RT H+ A H S P T
Sbjct: 1493 QQGTMWQGRNDMTYNYANRQSTGSAPQGPAY-HGVNRTDEMLHTDQRA-NHEGSWPSHGT 1550
Query: 367 NSMVDIPIVLINGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPATRSNSQTLSDAPF 424
P + P S Q P QN + P +SP+ P P N + S +PF
Sbjct: 1551 RQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHI-PQVSSPA-PLPRPMENRTSPSKSPF 1606
Score = 35.8 bits (81), Expect = 0.14
Identities = 64/309 (20%), Positives = 106/309 (34%), Gaps = 37/309 (11%)
Query: 205 GNQGRGHQRPLPP-SEGLSPRP---PNSPSISIPCMGSKASSPHGLGSPLVASPRLEKRL 260
G Q R H P+ P S G +P PS + MG P+G +P +++
Sbjct: 352 GAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYG-----GTNPYSQQQG 406
Query: 261 GGLAPQRGSRISVL---SASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSL 317
PQ+G S +P M G +QS + + + Q + P+
Sbjct: 407 PPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQ- 465
Query: 318 HSLGSVSLCTRPSDFQAPRNPTLTMGQP-RTPHSPPLAKEHASSCPPSITNSMVDIPIVL 376
G + S + P + P +TPH+ P ++ S PP + +S
Sbjct: 466 ---GQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSS-------- 514
Query: 377 INGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPATRSNSQTLSDAPFTTCPEGPARDMQ 436
+P S P HQ S P + S SQ P P + Q
Sbjct: 515 -----QPPYSQQPSQPPHQQSPAPYPSQQST--TQQHPQSQPPYSQPQAQSPYQQQQPQQ 567
Query: 437 PTMKFVMDTSKYWFKPNITREQAIELLRKEEPGAFVIRDSSSYRGSFGLALK-----VQE 491
P + + Y + +Q ++ P + +DS + S ++ ++
Sbjct: 568 PAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQED 627
Query: 492 VPASAQSRP 500
+ S QSRP
Sbjct: 628 MNLSLQSRP 636
Score = 32.7 bits (73), Expect = 1.2
Identities = 89/409 (21%), Positives = 130/409 (31%), Gaps = 69/409 (16%)
Query: 24 PRRTLHPAPSPSLPPQCSYYTTEGWGAQALMAPVPCMGPPGRLQQAPQVEAKATCFLP-- 81
P R+ +P P+P+ T G GA A P PP + + ++ F
Sbjct: 217 PNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKP---PP---SSSASASSSSSSFAQQR 270
Query: 82 -------SPGEKALGTPEDLDSYIDFSLESLNQMILELDPT--FQLLPPG--TGGSQ--- 127
P GTP+ + +LNQ++ +Q P G +GG Q
Sbjct: 271 FGAMGGGGPSAAGGGTPQPT------ATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGG 324
Query: 128 AELAQSTMSMRKKEESEALDIKYIEVTSARSRCHDGPQHCSSPSVTPPFGSLRSGGLLLS 187
A + M+ + + A A+ R H P SP GS GG L+
Sbjct: 325 AGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPM---SP------GSSGGGGQPLA 375
Query: 188 RDVPRETRSSSESLIFSGNQGRGHQRPLPPSEGLSPRPPNSPSISIPCMGSKASSPHGLG 247
R + S + + Q G P +G PP+ P G S
Sbjct: 376 R--TPQPSSPMDQMGKMRPQPYGGTNPYSQQQG----PPSGPQQGHGYPGQPYGSQTPQR 429
Query: 248 SPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSL 307
P+ R + +GGL S + S Q+ ++ S H +
Sbjct: 430 YPMTMQGRAQSAMGGL-----SYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPP 484
Query: 308 ESPANSSSSLHSLGSVSLCTRPSDFQAPRN--PTLTMGQPRTPHSPPLAKEHASSCPPSI 365
S S + H+ +PS Q P++ P L QP P S P
Sbjct: 485 YSQQPPSQTPHA--------QPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPS 536
Query: 366 TNSMVDIPIVLINGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPATRS 414
S P S PP P Q+ Q P P P+T S
Sbjct: 537 QQSTTQ---------QHPQSQPPYSQPQAQSPYQ--QQQPQQPAPSTLS 574
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 42.0 bits (97), Expect = 0.002
Identities = 58/218 (26%), Positives = 79/218 (36%), Gaps = 40/218 (18%)
Query: 214 PLPPSEGLSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISV 273
PLPP L R P + + S S S P P + + L G PQ R
Sbjct: 334 PLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRP----PTVFRLLEGRGPQTPRRSRP 389
Query: 274 LSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQ 333
+ +PV + SQ +L S S L +P S HS GS +L SD
Sbjct: 390 RAPAPVPQPFSLPEPSQPILPSV-----LSLLGLPTPGPS----HSDGSFNLLG--SDAH 438
Query: 334 APRNPTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPGSSPPQRTPG 393
P PTL+ G P P P S P + + S+ +P G P P ++
Sbjct: 439 LPPPPTLSSGSPPQPRHP-----IQPSLPGTTSGSLSSVP-----GAPAPPAA------- 481
Query: 394 HQNSVQPGAASPSNPCPATRSNSQTLSDAPFTTCPEGP 431
+ +P P P +S S+ L CP P
Sbjct: 482 --------SKAPVVPSPVLQSPSEGLGMGAGPACPLPP 511
>gi|14149916 Src-like-adaptor 2 isoform a [Homo sapiens]
Length = 261
Score = 41.6 bits (96), Expect = 0.003
Identities = 42/134 (31%), Positives = 59/134 (44%), Gaps = 14/134 (10%)
Query: 424 FTTCPEGPARDMQPTMKFVMDTSKYWFKPNITREQAIELLRK--EEPGAFVIRDSSSYRG 481
+T E R+ V S W ++RE+A ELL GAF+IR+S + RG
Sbjct: 69 WTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRG 128
Query: 482 SFGLALKVQEVPASAQSRPGEDSNDLIRHFLIESSAKGVHLKGADEEPYFGSLSAFVCQH 541
S+ L++++ SRP S D IRH+ I G F SL A V +
Sbjct: 129 SYSLSVRL--------SRPA--SWDRIRHYRIHCLDNG--WLYISPRLTFPSLQALVDHY 176
Query: 542 SIMALALPCKLTIP 555
S +A + C L P
Sbjct: 177 SELADDICCLLKEP 190
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 41.2 bits (95), Expect = 0.003
Identities = 64/261 (24%), Positives = 97/261 (37%), Gaps = 19/261 (7%)
Query: 169 SPSVTPPFGSLRSGGLLLSRDVPRETRSSSESLIFSG----NQGRGHQRPLPPSEGLSPR 224
SP+ PP ++ + P S +ES G + G Q P P +G P+
Sbjct: 520 SPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGP-SPGDGSPPK 578
Query: 225 PPNSPSISIPCMGSKASS-PHGLGSPLVASPRLEKRLG------GLAPQRGSRISVLSAS 277
P + S ++P G S G P A+ + +G G +P R A
Sbjct: 579 PKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAP 638
Query: 278 PVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSS--SLHSLGSVSLCTRPSDFQAP 335
SS +S S S + P S S + H+ + PS AP
Sbjct: 639 APPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAP 698
Query: 336 RNPTLTMGQPRTP-HSPPLAKEHASSCPPSITNSM-VDIPIVL--INGCPEPGSSPPQRT 391
R + ++ + P H PP A+ + NS P+ L +G +P +PPQ T
Sbjct: 699 RRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQ-T 757
Query: 392 PGHQNSVQPGAASPSNPCPAT 412
P ++ G +PS P P T
Sbjct: 758 PTPPSTPPLGKQNPSLPAPQT 778
Score = 32.7 bits (73), Expect = 1.2
Identities = 64/266 (24%), Positives = 92/266 (34%), Gaps = 39/266 (14%)
Query: 214 PLPPSEGLSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISV 273
P PP G +P PP P G+ P P SP + G P + S S
Sbjct: 638 PAPPKPG-NP-PPGHPG-GQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQ 694
Query: 274 LSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQ 333
LSA + SS S + + N + P ++ +H T+P+ Q
Sbjct: 695 LSAPR------RYSSSLSPIQAPNHPPP------QPPTQATPLMH--------TKPNS-Q 733
Query: 334 APRNPTLTM---GQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPGSSPPQR 390
P NP G + H+PP S+ P N + P L G PE + P
Sbjct: 734 GPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPET-AQPHAG 792
Query: 391 TPGHQNSVQPGAASPSNPCPATRSNSQTLSDAPFT-TCPEGPARDMQPTMKFVMDTSKYW 449
T V PS P P + D+ T T P K V D++
Sbjct: 793 TLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAP--------TASKIVTDSNSRV 844
Query: 450 FKP--NITREQAIELLRKEEPGAFVI 473
+P +I E + K+ PG ++
Sbjct: 845 SEPHRSIFPEMHSDSASKDVPGRILL 870
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,112,631
Number of Sequences: 37866
Number of extensions: 1865286
Number of successful extensions: 9169
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 528
Number of HSP's that attempted gapping in prelim test: 7943
Number of HSP's gapped (non-prelim): 1568
length of query: 715
length of database: 18,247,518
effective HSP length: 109
effective length of query: 606
effective length of database: 14,120,124
effective search space: 8556795144
effective search space used: 8556795144
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.