Guide to the Human Genome
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Name: CISH Sequence: fasta or formatted (275aa) NCBI GI: 195976771
Description:

cytokine-inducible SH2-containing protein isoform 1

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt prot [258aa] cytokine-inducible SH2-containing protein isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.7         24           1
 C cysteine            2.2          6           1
 D aspartate           6.5         18           3
 E glutamate           5.5         15           2
 F phenylalanine       2.9          8           1
 G glycine             2.5          7           1
 H histidine           3.3          9           2
 I isoleucine          1.8          5           1
 K lysine              2.5          7           1
 L leucine            12.0         33           2
 M methionine          2.2          6           1
 N asparagine          1.1          3           1
 P proline            12.7         35           3
 Q glutamine           3.6         10           1
 R arginine            7.6         21           2
 S serine              8.0         22           2
 T threonine           6.5         18           2
 V valine              6.2         17           2
 W tryptophan          1.1          3           1
 Y tyrosine            2.9          8           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   cytokine-inducible SH2-containing protein isoform 1... 
CISH                  0.899   cytokine-inducible SH2-containing protein isoform 2 ...
SOCS2                 0.247   suppressor of cytokine signaling-2 
SOCS3                 0.147   suppressor of cytokine signaling 3 
SOCS6                 0.109   suppressor of cytokine signaling 6 
SOCS1                 0.096   suppressor of cytokine signaling 1 
SOCS7                 0.094   suppressor of cytokine signaling 7 
SOCS4                 0.090   suppressor of cytokine signaling 4 
SOCS4                 0.090   suppressor of cytokine signaling 4 
SOCS5                 0.079   suppressor of cytokine signaling 5 
SOCS5                 0.079   suppressor of cytokine signaling 5 
PIK3R2                0.055   phosphoinositide-3-kinase, regulatory subunit 2 (beta...
PIK3R3                0.053   phosphoinositide-3-kinase, regulatory subunit 3 (p5...
PIK3R3                0.053   phosphoinositide-3-kinase, regulatory subunit 3 (p5...
PIK3R1                0.044   phosphoinositide-3-kinase, regulatory subunit 1 (alp...
PIK3R1                0.044   phosphoinositide-3-kinase, regulatory subunit 1 (alp...
PIK3R1                0.044   phosphoinositide-3-kinase, regulatory subunit 1 (alp...
TNS4                  0.033   tensin 4 
SHF                   0.031   Src homology 2 domain containing F 
DAPP1                 0.031   dual adaptor of phosphotyrosine and 3-phosphoinosit...
CSK                   0.029   c-src tyrosine kinase 
CSK                   0.029   c-src tyrosine kinase 
MATK                  0.029   megakaryocyte-associated tyrosine kinase isoform c [...
MATK                  0.029   megakaryocyte-associated tyrosine kinase isoform b [...
MATK                  0.029   megakaryocyte-associated tyrosine kinase isoform a [...
FER                   0.028   fer (fps/fes related) tyrosine kinase 
SHE                   0.028   Src homology 2 domain containing E 
CRK                   0.028   v-crk sarcoma virus CT10 oncogene homolog isoform a ...
CRK                   0.028   v-crk sarcoma virus CT10 oncogene homolog isoform b ...
NCK2                  0.026   NCK adaptor protein 2 isoform A 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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