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Search of human proteins with 157502177
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157502177 tetratricopeptide repeat domain 21A isoform 2
[Homo sapiens]
(1320 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157502177 tetratricopeptide repeat domain 21A isoform 2 [Homo... 2622 0.0
gi|157502179 tetratricopeptide repeat domain 21A isoform 1 [Homo... 2617 0.0
gi|116089292 tetratricopeptide repeat domain 21B [Homo sapiens] 1367 0.0
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 51 6e-06
gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] 50 1e-05
gi|83415184 transmembrane and tetratricopeptide repeat containin... 50 1e-05
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 45 6e-04
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 45 6e-04
gi|34304360 nephrocystin 3 [Homo sapiens] 44 8e-04
gi|22749211 transmembrane and tetratricopeptide repeat containin... 44 0.001
gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi... 42 0.004
gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi... 42 0.004
gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap... 40 0.019
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 39 0.025
gi|118402596 cell division cycle protein 23 [Homo sapiens] 39 0.043
gi|224809432 transmembrane and tetratricopeptide repeat containi... 38 0.056
gi|110225358 tetratricopeptide repeat domain 7A [Homo sapiens] 37 0.096
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 37 0.16
gi|17149828 NMDA receptor regulated 1 [Homo sapiens] 37 0.16
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 36 0.21
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 36 0.21
gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo ... 36 0.21
gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo ... 36 0.21
gi|15619013 43 kD receptor-associated protein of the synapse iso... 35 0.48
gi|209976994 adenylate cyclase 10 [Homo sapiens] 35 0.62
gi|60685231 tetratricopeptide repeat domain 7B [Homo sapiens] 35 0.62
gi|4503729 FK506 binding protein 52 [Homo sapiens] 34 1.1
gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 33 1.4
gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 33 1.4
gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Hom... 33 1.4
>gi|157502177 tetratricopeptide repeat domain 21A isoform 2 [Homo
sapiens]
Length = 1320
Score = 2622 bits (6796), Expect = 0.0
Identities = 1320/1320 (100%), Positives = 1320/1320 (100%)
Query: 1 MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS 60
MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
Sbjct: 1 MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS 60
Query: 61 DLESIRHHPDVSLCSTMALIYAHKRCEIIDREAIQELEYSLKEIRKTVSGTALYYAGLFL 120
DLESIRHHPDVSLCSTMALIYAHKRCEIIDREAIQELEYSLKEIRKTVSGTALYYAGLFL
Sbjct: 61 DLESIRHHPDVSLCSTMALIYAHKRCEIIDREAIQELEYSLKEIRKTVSGTALYYAGLFL 120
Query: 121 WLIGRHDKAKEYIDRMLKISRGFREAYVLRGWVDLTSDKPHTAKKAIEYLEQGIQDTKDV 180
WLIGRHDKAKEYIDRMLKISRGFREAYVLRGWVDLTSDKPHTAKKAIEYLEQGIQDTKDV
Sbjct: 121 WLIGRHDKAKEYIDRMLKISRGFREAYVLRGWVDLTSDKPHTAKKAIEYLEQGIQDTKDV 180
Query: 181 LGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQTVEMGHRI 240
LGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQTVEMGHRI
Sbjct: 181 LGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQTVEMGHRI 240
Query: 241 LEKDESNIDACQILTVHELAREGNMTTVSSLKTQKATNHVRNLIKALETREPENPSLHLK 300
LEKDESNIDACQILTVHELAREGNMTTVSSLKTQKATNHVRNLIKALETREPENPSLHLK
Sbjct: 241 LEKDESNIDACQILTVHELAREGNMTTVSSLKTQKATNHVRNLIKALETREPENPSLHLK 300
Query: 301 KIIVVSRLCGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWYSEA 360
KIIVVSRLCGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWYSEA
Sbjct: 301 KIIVVSRLCGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWYSEA 360
Query: 361 MKLDKDGMAGLTGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSRKHK 420
MKLDKDGMAGLTGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSRKHK
Sbjct: 361 MKLDKDGMAGLTGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSRKHK 420
Query: 421 GEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFLVCIAKEYLLFCPKQPRLPGQIV 480
GEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFLVCIAKEYLLFCPKQPRLPGQIV
Sbjct: 421 GEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFLVCIAKEYLLFCPKQPRLPGQIV 480
Query: 481 SPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYSELENAQSILQRCLELDPASVDAHLL 540
SPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYSELENAQSILQRCLELDPASVDAHLL
Sbjct: 481 SPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYSELENAQSILQRCLELDPASVDAHLL 540
Query: 541 MCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVIK 600
MCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVIK
Sbjct: 541 MCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVIK 600
Query: 601 LPALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEEN 660
LPALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEEN
Sbjct: 601 LPALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEEN 660
Query: 661 RITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYRE 720
RITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYRE
Sbjct: 661 RITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYRE 720
Query: 721 LCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTE 780
LCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTE
Sbjct: 721 LCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTE 780
Query: 781 AIEYYEAAQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCL 840
AIEYYEAAQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCL
Sbjct: 781 AIEYYEAAQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCL 840
Query: 841 LLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYL 900
LLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYL
Sbjct: 841 LLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYL 900
Query: 901 AEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETAS 960
AEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETAS
Sbjct: 901 AEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETAS 960
Query: 961 VLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKV 1020
VLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKV
Sbjct: 961 VLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKV 1020
Query: 1021 SSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPDNEVV 1080
SSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPDNEVV
Sbjct: 1021 SSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPDNEVV 1080
Query: 1081 GGEAFENQGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQGLCRLATREK 1140
GGEAFENQGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQGLCRLATREK
Sbjct: 1081 GGEAFENQGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQGLCRLATREK 1140
Query: 1141 ANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWVLSEAEDL 1200
ANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWVLSEAEDL
Sbjct: 1141 ANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWVLSEAEDL 1200
Query: 1201 EKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYKL 1260
EKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYKL
Sbjct: 1201 EKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYKL 1260
Query: 1261 AWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLREHPDYPKIREEILEKARRSLRP 1320
AWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLREHPDYPKIREEILEKARRSLRP
Sbjct: 1261 AWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLREHPDYPKIREEILEKARRSLRP 1320
>gi|157502179 tetratricopeptide repeat domain 21A isoform 1 [Homo
sapiens]
Length = 1321
Score = 2617 bits (6784), Expect = 0.0
Identities = 1320/1321 (99%), Positives = 1320/1321 (99%), Gaps = 1/1321 (0%)
Query: 1 MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS 60
MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS
Sbjct: 1 MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAIS 60
Query: 61 DLESIRHHPDVSLCSTMALIYAHKRCEIIDREAIQELEYSLKEIRKTVSGTALYYAGLFL 120
DLESIRHHPDVSLCSTMALIYAHKRCEIIDREAIQELEYSLKEIRKTVSGTALYYAGLFL
Sbjct: 61 DLESIRHHPDVSLCSTMALIYAHKRCEIIDREAIQELEYSLKEIRKTVSGTALYYAGLFL 120
Query: 121 WLIGRHDKAKEYIDRMLKISRGFREAYVLRGWVDLTSDKPHTAKKAIEYLEQGIQDTKDV 180
WLIGRHDKAKEYIDRMLKISRGFREAYVLRGWVDLTSDKPHTAKKAIEYLEQGIQDTKDV
Sbjct: 121 WLIGRHDKAKEYIDRMLKISRGFREAYVLRGWVDLTSDKPHTAKKAIEYLEQGIQDTKDV 180
Query: 181 LGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQTVEMGHRI 240
LGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQTVEMGHRI
Sbjct: 181 LGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQTVEMGHRI 240
Query: 241 LEKDESNIDACQILTVHELAREGNMTTVSSLKTQKATNHVRNLIKALETREPENPSLHLK 300
LEKDESNIDACQILTVHELAREGNMTTVSSLKTQKATNHVRNLIKALETREPENPSLHLK
Sbjct: 241 LEKDESNIDACQILTVHELAREGNMTTVSSLKTQKATNHVRNLIKALETREPENPSLHLK 300
Query: 301 KIIVVSRLCGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWYSEA 360
KIIVVSRLCGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWYSEA
Sbjct: 301 KIIVVSRLCGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWYSEA 360
Query: 361 MKLDKDGMAGLTGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSRKHK 420
MKLDKDGMAGLTGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSRKHK
Sbjct: 361 MKLDKDGMAGLTGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSRKHK 420
Query: 421 GEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFLVCIAKEYLLFCPKQPRLPGQIV 480
GEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFLVCIAKEYLLFCPKQPRLPGQIV
Sbjct: 421 GEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFLVCIAKEYLLFCPKQPRLPGQIV 480
Query: 481 SPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYS-ELENAQSILQRCLELDPASVDAHL 539
SPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYS ELENAQSILQRCLELDPASVDAHL
Sbjct: 481 SPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYSGELENAQSILQRCLELDPASVDAHL 540
Query: 540 LMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVI 599
LMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVI
Sbjct: 541 LMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVI 600
Query: 600 KLPALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEE 659
KLPALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEE
Sbjct: 601 KLPALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEE 660
Query: 660 NRITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYR 719
NRITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYR
Sbjct: 661 NRITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYR 720
Query: 720 ELCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYT 779
ELCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYT
Sbjct: 721 ELCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYT 780
Query: 780 EAIEYYEAAQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKC 839
EAIEYYEAAQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKC
Sbjct: 781 EAIEYYEAAQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKC 840
Query: 840 LLLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHY 899
LLLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHY
Sbjct: 841 LLLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHY 900
Query: 900 LAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETA 959
LAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETA
Sbjct: 901 LAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETA 960
Query: 960 SVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKK 1019
SVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKK
Sbjct: 961 SVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKK 1020
Query: 1020 VSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPDNEV 1079
VSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPDNEV
Sbjct: 1021 VSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPDNEV 1080
Query: 1080 VGGEAFENQGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQGLCRLATRE 1139
VGGEAFENQGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQGLCRLATRE
Sbjct: 1081 VGGEAFENQGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQGLCRLATRE 1140
Query: 1140 KANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWVLSEAED 1199
KANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWVLSEAED
Sbjct: 1141 KANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWVLSEAED 1200
Query: 1200 LEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYK 1259
LEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYK
Sbjct: 1201 LEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYK 1260
Query: 1260 LAWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLREHPDYPKIREEILEKARRSLR 1319
LAWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLREHPDYPKIREEILEKARRSLR
Sbjct: 1261 LAWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLREHPDYPKIREEILEKARRSLR 1320
Query: 1320 P 1320
P
Sbjct: 1321 P 1321
>gi|116089292 tetratricopeptide repeat domain 21B [Homo sapiens]
Length = 1316
Score = 1367 bits (3537), Expect = 0.0
Identities = 676/1315 (51%), Positives = 941/1315 (71%), Gaps = 14/1315 (1%)
Query: 12 IIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAISDLESIRHHPDV 71
I YY QE+YFHHV A+ G++++ +DPV +F+ AYG L E Q+A+ + E+I++ DV
Sbjct: 10 INYYCQERYFHHVLLVASEGIKRYGSDPVFRFYHAYGTLMEGKTQEALREFEAIKNKQDV 69
Query: 72 SLCSTMALIYAHKRCEIIDREAIQELEYSLKEIRKTVSGTALYYAGLFLWLIGRHDKAKE 131
SLCS +ALIYAHK DREAI E + +KE RK ALY+AGLFLW IGRHDKA+E
Sbjct: 70 SLCSLLALIYAHKMSPNPDREAILESDARVKEQRKGAGEKALYHAGLFLWHIGRHDKARE 129
Query: 132 YIDRMLKISRGFREAYVLRGWVDLTSDKPHTAKKAIEYLEQGIQDTKDVLGLMGKAMYFM 191
YIDRM+KIS G ++ +VL+ W+D+T K KKA++Y E+G+QD D L+GKA
Sbjct: 130 YIDRMIKISDGSKQGHVLKAWLDITRGKEPYTKKALKYFEEGLQDGNDTFALLGKAQCLE 189
Query: 192 MQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQTVEMGHRILEKDESNIDAC 251
M+QNYS ALE VNQI V SFLPA V KM+L LA QDW+QTVE R+L +D N++A
Sbjct: 190 MRQNYSGALETVNQIIVNFPSFLPAFVKKMKLQLALQDWDQTVETAQRLLLQDSQNVEAL 249
Query: 252 QILTVHELAREGNMTTVSSLKTQKATNHVRNLIKALETREPENPSLHLKKIIVVSRLCGS 311
++ ++ + REG++ +KA+ + NL L+ EP+N L + SR CG
Sbjct: 250 RMQALYYVCREGDI--------EKASTKLENLGNTLDAMEPQNAQLFYNITLAFSRTCGR 301
Query: 312 HQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWYSEAMKLDKDGMAGL 371
Q+IL + + +ER F P ATELGY IL+ +VKEAL WY AM LD+ ++ L
Sbjct: 302 SQLILQKIQTLLERAFSLNPQQSEFATELGYQMILQGRVKEALKWYKTAMTLDETSVSAL 361
Query: 372 TGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSRKHKGEEETTALLKE 431
G I C ++EG L++A+ +LEFL E+Q+S+GKS LI+L A+L +K+K +EE LL +
Sbjct: 362 VGFIQCQLIEGQLQDADQQLEFLNEIQQSIGKSAELIYLHAVLAMKKNKRQEEVINLLND 421
Query: 432 AVELHFSSMQGIPLGSEYFEKLDPYFLVCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVIL 491
++ HFS ++G+PLG +YFEKL+P FL+ I EYL FCP QP PGQ + PLL++ +L
Sbjct: 422 VLDTHFSQLEGLPLGIQYFEKLNPDFLLEIVMEYLSFCPMQPASPGQPLCPLLRRCISVL 481
Query: 492 NPVVKAAPALIDPLYLMAQVRYYS-ELENAQSILQRCLELDPASVDAHLLMCQIYLAQGN 550
VV+ P L+ ++L+A+V+Y S ++E A + LQ CLE +P+ DAHLL+ Q+YL+Q
Sbjct: 482 ETVVRTVPGLLQTVFLIAKVKYLSGDIEAAFNNLQHCLEHNPSYADAHLLLAQVYLSQEK 541
Query: 551 FGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKK---E 607
+C LEL +S++F+VRD+PLYHLIKA++ K G+ +AIKTL M + LP +K+
Sbjct: 542 VKLCSQSLELCLSYDFKVRDYPLYHLIKAQSQKKMGEIADAIKTLHMAMSLPGMKRIGAS 601
Query: 608 EGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANV 667
K + V S R SI LEL++ RLNGE HEATKV+QD I+EF GT EE R+TIAN
Sbjct: 602 TKSKDRKTEVDTSHRLSIFLELIDVHRLNGEQHEATKVLQDAIHEFSGTSEEVRVTIANA 661
Query: 668 DLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYRELCEHLPG 727
DL L++G+++ AL++L+N+ +Q ++EAREKMA+IYL+ +D+ LYI C+RE+ E +
Sbjct: 662 DLALAQGDIERALSILQNVTAEQPYFIEAREKMADIYLKHRKDKMLYITCFREIAERMAN 721
Query: 728 PHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEA 787
P + LLLGDA M+ILEPE+A+ Y++A QNP D +LAS++G A +K H Y+ AI YYEA
Sbjct: 722 PRSFLLLGDAYMNILEPEEAIVAYEQALNQNPKDGTLASKMGKALIKTHNYSMAITYYEA 781
Query: 788 AQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVY 847
A K +++LC DL +LLLKLK +KAEKVL+ AL H+ V ++ ++M D +C +LLAKVY
Sbjct: 782 ALKTGQKNYLCYDLAELLLKLKWYDKAEKVLQHALAHEPVNELSALMEDGRCQVLLAKVY 841
Query: 848 -KSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKEYD 906
K K I L +A +LQ+R+LKRV +EQP+ +P+QK LAA IC + A+H +A+++Y+
Sbjct: 842 SKMEKLGDAITALQQARELQARVLKRVQMEQPDAVPAQKHLAAEICAEIAKHSVAQRDYE 901
Query: 907 KAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADL 966
KA++ Y++ + TDNK+MLELA+LYL Q D C + CA+LLQ++Q++E A+++MADL
Sbjct: 902 KAIKFYREALVHCETDNKIMLELARLYLAQDDPDSCLRQCALLLQSDQDNEAATMMMADL 961
Query: 967 MFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKVSSRVPL 1026
MFRKQ +E A+ Q+LE+ PDN++ L +LIDLLRR GKLED+P FF +A+K +SR L
Sbjct: 962 MFRKQDYEQAVFHLQQLLERKPDNYMTLSRLIDLLRRCGKLEDVPRFFSMAEKRNSRAKL 1021
Query: 1027 EPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPDNEVVGGEAFE 1086
EPGF YC+G+Y W+ G+PN+AL+ NKARKD WGQ+A+Y+M++ICLNPDNE VGGE FE
Sbjct: 1022 EPGFQYCKGLYLWYTGEPNDALRHFNKARKDRDWGQNALYNMIEICLNPDNETVGGEVFE 1081
Query: 1087 N-QGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQGLCRLATREKANMEA 1145
N G N EK+E Q V TAEKLL+E P + QLR+++ C +AT++K+N+E
Sbjct: 1082 NLDGDLGNSTEKQESVQLAVRTAEKLLKELKPQTVQGHVQLRIMENYCLMATKQKSNVEQ 1141
Query: 1146 ALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWVLSEAEDLEKSWL 1205
AL +F +IA +EK+ +PALL +A AY+ LKQ P+AR QLKR+AK W +AE+ EKSWL
Sbjct: 1142 ALNTFTEIAASEKEHIPALLGMATAYMILKQTPRARNQLKRIAKMNWNAIDAEEFEKSWL 1201
Query: 1206 LLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYKLAWKYS 1265
LLADIY Q +K+D+A +LL+RC+++N+SC KAYEYMG+IMEKEQ+Y DA NY++AWKYS
Sbjct: 1202 LLADIYIQSAKYDMAEDLLKRCLRHNRSCCKAYEYMGYIMEKEQAYTDAALNYEMAWKYS 1261
Query: 1266 HHANPAIGFKLAFNYLKDKKFVEAIEICNDVLREHPDYPKIREEILEKARRSLRP 1320
+ NPA+G+KLAFNYLK K++V++I+IC+ VL HP YPKIR++IL+KAR SLRP
Sbjct: 1262 NRTNPAVGYKLAFNYLKAKRYVDSIDICHQVLEAHPTYPKIRKDILDKARASLRP 1316
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 51.2 bits (121), Expect = 6e-06
Identities = 117/600 (19%), Positives = 236/600 (39%), Gaps = 88/600 (14%)
Query: 733 LLGDALMSILEPEK--ALEVYDEAYRQNPH-DASLASRIGHAYVKAHQYTEAIEYYEAAQ 789
LLG A +S + + AL Y +A R NP A + +GH +VK ++ +A + A
Sbjct: 166 LLGKACISFNKKDYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRAL 225
Query: 790 KINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALE-----HDIVQDIPSMMNDVKCLLLLA 844
++N + C L L+ NK +K ++ + I P ++N +
Sbjct: 226 ELNSK---CVGALVGLAVLELNNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFK 282
Query: 845 KVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKE 904
K Y + A+ N ++ + A C Q A + +++
Sbjct: 283 KDYSKVQHLALHAFHNTEVEA---------------------MQAESCYQLARSFHVQED 321
Query: 905 YDKAVQSYKDVFSYLPTDNKV-MLELAQLYLLQGHLDLCEQHC--AILLQTEQNHETASV 961
YD+A Q Y + + + L Q+Y+ +G + Q C +L N+ET +
Sbjct: 322 YDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRGDKENASQ-CFEKVLKAYPNNYETMKI 380
Query: 962 L--MADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFE---- 1015
L + ++K + A +V E+ PD+ +L +L ++ + A+
Sbjct: 381 LGSLYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQILEQTDIQGALSAYGTATRI 440
Query: 1016 LAKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKF----LNKARKDSTWGQSAIYHMVQI 1071
L +KV + VP E N G + +G EA K+ L++A+ ++ + Y+ + +
Sbjct: 441 LQEKVQADVPPEILNNV--GALHFRLGNLGEAKKYFLASLDRAKAEAEHDEH-YYNAISV 497
Query: 1072 CLNPDNEVVGGEAFENQGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQG 1131
+ + + E AE Y + +LRE H + LRL
Sbjct: 498 TTSYNLARLYEAMCEFHEAEKLY--------------KNILRE---HPNYVDCYLRL--- 537
Query: 1132 LCRLATREKANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTP 1191
R+K N A F + Q +D A + ++ ++ + + +R+ K P
Sbjct: 538 --GAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQP 595
Query: 1192 WVLSEAEDLEKSWLLLADIYCQ------------GSKFDLALELLRRCVQYNKSCYKAYE 1239
S+ S L L +++ Q D AL + ++ ++ + A
Sbjct: 596 STQSDT----YSMLALGNVWLQTLHQPTRDREKEKRHQDRALAIYKQVLRNDAKNLYAAN 651
Query: 1240 YMGFIMEKEQSYKDAVTNYKLAWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLRE 1299
+G ++ + +++A + + + + + LA Y++ K+++ A+++ + LR+
Sbjct: 652 GIGAVLAHKGYFREARDVFAQVREATADISD-VWLNLAHIYVEQKQYISAVQMYENCLRK 710
Score = 37.7 bits (86), Expect = 0.073
Identities = 70/327 (21%), Positives = 130/327 (39%), Gaps = 54/327 (16%)
Query: 730 TSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQ 789
TS L ++ E +A ++Y R++P+ R+G + EA ++++ A
Sbjct: 499 TSYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWFKEAL 558
Query: 790 KINGQDF--LCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVY 847
+IN QD +G L L ++ +K ++ L+ PS +D +L L V+
Sbjct: 559 QIN-QDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQ------PSTQSDTYSMLALGNVW 611
Query: 848 ------KSHKKEAVIETLNKALDLQSRIL-------------------KRVPLEQPEMIP 882
+ +E ++AL + ++L K E ++
Sbjct: 612 LQTLHQPTRDREKEKRHQDRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFA 671
Query: 883 SQKQLAASIC---IQFAEHYLAEKEYDKAVQSYKDVFS--YLPTDNKVMLELAQLYLLQG 937
++ A I + A Y+ +K+Y AVQ Y++ Y + +V+L LA+ G
Sbjct: 672 QVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHQNTEVVLYLARALFKCG 731
Query: 938 HLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKL 997
L C+Q LL+ + +VLM ++ Q+ L VL+ N L
Sbjct: 732 KLQECKQ---TLLKARHVAPSDTVLMFNVALVLQR------LATSVLKDEKSN------L 776
Query: 998 IDLLRRSGKLEDIPAFFELAKKVSSRV 1024
++L +LE +F KV ++
Sbjct: 777 KEVLNAVKELELAHRYFSYLSKVGDKM 803
Score = 32.3 bits (72), Expect = 3.1
Identities = 38/182 (20%), Positives = 74/182 (40%), Gaps = 16/182 (8%)
Query: 700 MANIYLQTL--------RDRRLYIRCYRELCEHLPGPHTSLLLGDALMSILEPE----KA 747
+ N++LQTL +++R R + L +L + + ++L + +A
Sbjct: 607 LGNVWLQTLHQPTRDREKEKRHQDRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREA 666
Query: 748 LEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQK---INGQDFLCCDLGKL 804
+V+ + + + + H YV+ QY A++ YE + + + L +
Sbjct: 667 RDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHQNTEVVLYLARA 726
Query: 805 LLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEAVIETLNKALD 864
L K K+ + ++ L +A H D M N L LA +K + E LN +
Sbjct: 727 LFKCGKLQECKQTLLKA-RHVAPSDTVLMFNVALVLQRLATSVLKDEKSNLKEVLNAVKE 785
Query: 865 LQ 866
L+
Sbjct: 786 LE 787
>gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]
Length = 519
Score = 50.4 bits (119), Expect = 1e-05
Identities = 57/257 (22%), Positives = 108/257 (42%), Gaps = 34/257 (13%)
Query: 745 EKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQDF-LCCDLGK 803
+++LE++ +P A ++ + ++ AIE Y A K+N +D+ + +LG
Sbjct: 84 QESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAAIEVYNEAAKLNQKDWEISHNLGV 143
Query: 804 LLLKLKKVNKAEKVLKQAL---EHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEAVIETLN 860
+ LK+ NKA+ L AL HD+ ++L K+ H E L+
Sbjct: 144 CYIYLKQFNKAQDQLHNALNLNRHDLT------------YIMLGKI---HLLEG---DLD 185
Query: 861 KALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLP 920
KA+++ + ++ P E E++ + L YL Y KA + + +Y P
Sbjct: 186 KAIEVYKKAVEFSP-ENTELLTTLGLL-----------YLQLGIYQKAFEHLGNALTYDP 233
Query: 921 TDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKHEAAINLY 980
T+ K +L + G D+ ++ + F K+K+ AAI+
Sbjct: 234 TNYKAILAAGSMMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCFFGKKKYVAAISCL 293
Query: 981 HQVLEKAPDNFLVLHKL 997
+ AP ++ +L+ L
Sbjct: 294 KRANYLAPFDWKILYNL 310
Score = 34.3 bits (77), Expect = 0.81
Identities = 44/205 (21%), Positives = 88/205 (42%), Gaps = 9/205 (4%)
Query: 584 KAGDYPEAIKTLKMVIKLPALKK--EEGRKFLRPSVQPSQRASILLELVEAL--RLNGEL 639
KA ++P ++ +I L ++K E + ++ +Q +Q V+AL RL G +
Sbjct: 25 KAPEFP-ILEKQNWLIHLHYIRKDYEACKAVIKEQLQETQGLCEYAIYVQALIFRLEGNI 83
Query: 640 HEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREK 699
E+ ++ Q T +N +A +L K + + L ++ +
Sbjct: 84 QESLELFQ-TCAVLSPQSADNLKQVARSLFLLGKHKAAIEVYNEAAKLNQKDWEISHNLG 142
Query: 700 MANIYLQTLRDRRLYIRCYRELCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNP 759
+ IYL+ + + L H T ++LG + + +KA+EVY +A +P
Sbjct: 143 VCYIYLKQFNKAQDQLHNALNLNRH---DLTYIMLGKIHLLEGDLDKAIEVYKKAVEFSP 199
Query: 760 HDASLASRIGHAYVKAHQYTEAIEY 784
+ L + +G Y++ Y +A E+
Sbjct: 200 ENTELLTTLGLLYLQLGIYQKAFEH 224
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 50.4 bits (119), Expect = 1e-05
Identities = 68/361 (18%), Positives = 142/361 (39%), Gaps = 36/361 (9%)
Query: 657 PEENRITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIR 716
P+ NR +L+ S+ + A+ +L++ + + +A +A++ + R +
Sbjct: 437 PQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAE-E 495
Query: 717 CYRELCEHLPGP---HTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYV 773
Y+ ++ P H + G L+ PEKA+ Y +A + +P +G Y
Sbjct: 496 IYQTGIKNCPDSSDLHNNY--GVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYR 553
Query: 774 KAHQYTEAIEYYEAAQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSM 833
+ + A E+Y+ A ++ + + LG L + +A ++ ++A +
Sbjct: 554 SLGENSMAEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQEAAA------LQPS 607
Query: 834 MNDVKCLLLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICI 893
+++ L KEA ++ + E+ + + L+A
Sbjct: 608 QRELRLALAQVLAVMGQTKEA------------EKMTNHIVSEETGCLECYRLLSAI--- 652
Query: 894 QFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLEL----AQLYLLQGHLDLCEQHCAIL 949
Y ++ +DKA+ + P D KV+ EL Q LD + +
Sbjct: 653 -----YSKQENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNLLDKAFESYRVA 707
Query: 950 LQTEQNHETASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLED 1009
+Q + A + M + K K+ +A Y + L+ PD+ L+ L L R +L++
Sbjct: 708 VQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLKENLAKLDRLEKRLQE 767
Query: 1010 I 1010
+
Sbjct: 768 V 768
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 44.7 bits (104), Expect = 6e-04
Identities = 65/282 (23%), Positives = 114/282 (40%), Gaps = 21/282 (7%)
Query: 754 AYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQDFL--CCDLGKLLLKLKKV 811
A +QNP A S +G+ Y + Q EAIE+Y A ++ DF+ +L L+ +
Sbjct: 71 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLK-PDFIDGYINLAAALVAAGDM 129
Query: 812 NKAEKVLKQALEHDIVQDIPSMMNDVKCLL-----------LLAKVYKSHKKEAVI-ETL 859
A + AL+++ D+ + +D+ LL K ++ AV L
Sbjct: 130 EGAVQAYVSALQYN--PDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNL 187
Query: 860 NKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKE-YDKAVQSYKDVFSY 918
+ Q I + + + L A I + + L E +D+AV +Y S
Sbjct: 188 GCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLG---NVLKEARIFDRAVAAYLRALSL 244
Query: 919 LPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKHEAAIN 978
P V LA +Y QG +DL ++ + + A +A+ + K A +
Sbjct: 245 SPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAED 304
Query: 979 LYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKV 1020
Y+ L P + L+ L ++ R G +E+ + A +V
Sbjct: 305 CYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEV 346
Score = 40.8 bits (94), Expect = 0.009
Identities = 64/304 (21%), Positives = 125/304 (41%), Gaps = 23/304 (7%)
Query: 734 LGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKING 793
LG+ + ++A+E Y A R P + A V A A++ Y +A + N
Sbjct: 85 LGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYN- 143
Query: 794 QDFLCC--DLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLL-LLAKVYKS- 849
D C DLG LL L ++ +A+ +A+E + +++ C+ +++ +
Sbjct: 144 PDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQ--PNFAVAWSNLGCVFNAQGEIWLAI 201
Query: 850 -HKKEAVI---ETLNKALDL-----QSRILKRVP---LEQPEMIPSQKQLAASICIQFAE 897
H ++AV L+ ++L ++RI R L + P+ + ++ + E
Sbjct: 202 HHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYE 261
Query: 898 HYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHE 957
L D A+ +Y+ P LA +G + E L+ H
Sbjct: 262 QGLI----DLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHA 317
Query: 958 TASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELA 1017
+ +A++ + E A+ LY + LE P+ L +L++ GKL++ ++ A
Sbjct: 318 DSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEA 377
Query: 1018 KKVS 1021
++S
Sbjct: 378 IRIS 381
Score = 33.5 bits (75), Expect = 1.4
Identities = 37/164 (22%), Positives = 69/164 (42%), Gaps = 5/164 (3%)
Query: 629 LVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALNMLRNILP 688
L AL+ G + EA +T T ++ +AN+ +GN++ A+ + R L
Sbjct: 289 LANALKEKGSVAEAEDCY-NTALRLCPTHADSLNNLANIKR--EQGNIEEAVRLYRKALE 345
Query: 689 KQSCYMEAREKMANIYLQTLRDRRLYIRCYRELCEHLPGPHTSLL-LGDALMSILEPEKA 747
+ A +A++ Q + + + Y+E P + +G+ L + + + A
Sbjct: 346 VFPEFAAAHSNLASVLQQQGKLQEALMH-YKEAIRISPTFADAYSNMGNTLKEMQDVQGA 404
Query: 748 LEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKI 791
L+ Y A + NP A S + + + EAI Y A K+
Sbjct: 405 LQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKL 448
Score = 31.6 bits (70), Expect = 5.3
Identities = 45/198 (22%), Positives = 75/198 (37%), Gaps = 19/198 (9%)
Query: 484 LKQVAVILNPVVKAAPALIDPLYLMAQVRYYSELENAQSILQ---RCLELDPASVDAHLL 540
L++ + ++ +P D M E+++ Q LQ R ++++PA DAH
Sbjct: 367 LQEALMHYKEAIRISPTFADAYSNMGNT--LKEMQDVQGALQCYTRAIQINPAFADAHSN 424
Query: 541 MCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVIK 600
+ I+ GN + D P + A L D+ + + +K ++
Sbjct: 425 LASIHKDSGNIPEAIASYRTALKLK---PDFPDAYCNLAHCLQIVCDWTDYDERMKKLVS 481
Query: 601 LPALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEEN 660
+ A + E+ R PSV P S+L L R + D IN P E+
Sbjct: 482 IVADQLEKNR---LPSVHPHH--SMLYPLSHGFR-KAIAERHGNLCLDKINVLHKPPYEH 535
Query: 661 RITIANVDLVLSKGNVDV 678
DL LS G + V
Sbjct: 536 -----PKDLKLSDGRLRV 548
Score = 30.8 bits (68), Expect = 9.0
Identities = 62/284 (21%), Positives = 104/284 (36%), Gaps = 39/284 (13%)
Query: 517 LENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHL 576
LE A++ + +E P A + ++ AQG + H E V+ + D ++
Sbjct: 163 LEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDA---YI 219
Query: 577 IKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKFLRPSVQPSQRASILLELV-----E 631
L +A + A+ L AL + ++ L++L
Sbjct: 220 NLGNVLKEARIFDRAVAAY-----LRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRR 274
Query: 632 ALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALNMLRNILPKQS 691
A+ L +A + + + E G E N L L + D +LN L NI +Q
Sbjct: 275 AIELQPHFPDAYCNLANALKEKGSVAEAE--DCYNTALRLCPTHAD-SLNNLANIKREQG 331
Query: 692 CYMEAREKMANIYLQTLRDRRLYIRCYRELCEHLP---GPHTSLLLGDALMSILEPEKAL 748
EA +R YR+ E P H++L L + ++AL
Sbjct: 332 NIEEA------------------VRLYRKALEVFPEFAAAHSNL--ASVLQQQGKLQEAL 371
Query: 749 EVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKIN 792
Y EA R +P A S +G+ + A++ Y A +IN
Sbjct: 372 MHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQIN 415
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 44.7 bits (104), Expect = 6e-04
Identities = 65/282 (23%), Positives = 114/282 (40%), Gaps = 21/282 (7%)
Query: 754 AYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQDFL--CCDLGKLLLKLKKV 811
A +QNP A S +G+ Y + Q EAIE+Y A ++ DF+ +L L+ +
Sbjct: 81 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLK-PDFIDGYINLAAALVAAGDM 139
Query: 812 NKAEKVLKQALEHDIVQDIPSMMNDVKCLL-----------LLAKVYKSHKKEAVI-ETL 859
A + AL+++ D+ + +D+ LL K ++ AV L
Sbjct: 140 EGAVQAYVSALQYN--PDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNL 197
Query: 860 NKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKE-YDKAVQSYKDVFSY 918
+ Q I + + + L A I + + L E +D+AV +Y S
Sbjct: 198 GCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLG---NVLKEARIFDRAVAAYLRALSL 254
Query: 919 LPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKHEAAIN 978
P V LA +Y QG +DL ++ + + A +A+ + K A +
Sbjct: 255 SPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAED 314
Query: 979 LYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKV 1020
Y+ L P + L+ L ++ R G +E+ + A +V
Sbjct: 315 CYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEV 356
Score = 40.8 bits (94), Expect = 0.009
Identities = 64/304 (21%), Positives = 125/304 (41%), Gaps = 23/304 (7%)
Query: 734 LGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKING 793
LG+ + ++A+E Y A R P + A V A A++ Y +A + N
Sbjct: 95 LGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYN- 153
Query: 794 QDFLCC--DLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLL-LLAKVYKS- 849
D C DLG LL L ++ +A+ +A+E + +++ C+ +++ +
Sbjct: 154 PDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQ--PNFAVAWSNLGCVFNAQGEIWLAI 211
Query: 850 -HKKEAVI---ETLNKALDL-----QSRILKRVP---LEQPEMIPSQKQLAASICIQFAE 897
H ++AV L+ ++L ++RI R L + P+ + ++ + E
Sbjct: 212 HHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYE 271
Query: 898 HYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHE 957
L D A+ +Y+ P LA +G + E L+ H
Sbjct: 272 QGLI----DLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHA 327
Query: 958 TASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELA 1017
+ +A++ + E A+ LY + LE P+ L +L++ GKL++ ++ A
Sbjct: 328 DSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEA 387
Query: 1018 KKVS 1021
++S
Sbjct: 388 IRIS 391
Score = 33.5 bits (75), Expect = 1.4
Identities = 37/164 (22%), Positives = 69/164 (42%), Gaps = 5/164 (3%)
Query: 629 LVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALNMLRNILP 688
L AL+ G + EA +T T ++ +AN+ +GN++ A+ + R L
Sbjct: 299 LANALKEKGSVAEAEDCY-NTALRLCPTHADSLNNLANIKR--EQGNIEEAVRLYRKALE 355
Query: 689 KQSCYMEAREKMANIYLQTLRDRRLYIRCYRELCEHLPGPHTSLL-LGDALMSILEPEKA 747
+ A +A++ Q + + + Y+E P + +G+ L + + + A
Sbjct: 356 VFPEFAAAHSNLASVLQQQGKLQEALMH-YKEAIRISPTFADAYSNMGNTLKEMQDVQGA 414
Query: 748 LEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKI 791
L+ Y A + NP A S + + + EAI Y A K+
Sbjct: 415 LQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKL 458
Score = 31.6 bits (70), Expect = 5.3
Identities = 45/198 (22%), Positives = 75/198 (37%), Gaps = 19/198 (9%)
Query: 484 LKQVAVILNPVVKAAPALIDPLYLMAQVRYYSELENAQSILQ---RCLELDPASVDAHLL 540
L++ + ++ +P D M E+++ Q LQ R ++++PA DAH
Sbjct: 377 LQEALMHYKEAIRISPTFADAYSNMGNT--LKEMQDVQGALQCYTRAIQINPAFADAHSN 434
Query: 541 MCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVIK 600
+ I+ GN + D P + A L D+ + + +K ++
Sbjct: 435 LASIHKDSGNIPEAIASYRTALKLK---PDFPDAYCNLAHCLQIVCDWTDYDERMKKLVS 491
Query: 601 LPALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEEN 660
+ A + E+ R PSV P S+L L R + D IN P E+
Sbjct: 492 IVADQLEKNR---LPSVHPHH--SMLYPLSHGFR-KAIAERHGNLCLDKINVLHKPPYEH 545
Query: 661 RITIANVDLVLSKGNVDV 678
DL LS G + V
Sbjct: 546 -----PKDLKLSDGRLRV 558
Score = 30.8 bits (68), Expect = 9.0
Identities = 62/284 (21%), Positives = 104/284 (36%), Gaps = 39/284 (13%)
Query: 517 LENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHL 576
LE A++ + +E P A + ++ AQG + H E V+ + D ++
Sbjct: 173 LEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDA---YI 229
Query: 577 IKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKFLRPSVQPSQRASILLELV-----E 631
L +A + A+ L AL + ++ L++L
Sbjct: 230 NLGNVLKEARIFDRAVAAY-----LRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRR 284
Query: 632 ALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALNMLRNILPKQS 691
A+ L +A + + + E G E N L L + D +LN L NI +Q
Sbjct: 285 AIELQPHFPDAYCNLANALKEKGSVAEAE--DCYNTALRLCPTHAD-SLNNLANIKREQG 341
Query: 692 CYMEAREKMANIYLQTLRDRRLYIRCYRELCEHLP---GPHTSLLLGDALMSILEPEKAL 748
EA +R YR+ E P H++L L + ++AL
Sbjct: 342 NIEEA------------------VRLYRKALEVFPEFAAAHSNL--ASVLQQQGKLQEAL 381
Query: 749 EVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKIN 792
Y EA R +P A S +G+ + A++ Y A +IN
Sbjct: 382 MHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQIN 425
>gi|34304360 nephrocystin 3 [Homo sapiens]
Length = 1330
Score = 44.3 bits (103), Expect = 8e-04
Identities = 65/293 (22%), Positives = 128/293 (43%), Gaps = 29/293 (9%)
Query: 745 EKALEVYDEAY-RQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQDFLCCDLGK 803
++ALE+ + AY +P+ A + Y K ++Y +A + + + KI+ K
Sbjct: 1009 KQALEISENAYGADHPYTARELEALATLYQKQNKYEQAEHFRKKSFKIHQ---------K 1059
Query: 804 LLLKLKKVNKAEKVLKQALEHD---IVQDIPSMMNDVKCLLLLAKVYKSHKKEAVIETLN 860
+ K + + ++AL+ + + +D P + L +L Y + E + L
Sbjct: 1060 AIKKKGNLYGFALLRRRALQLEELTLGKDTPDNARTLNELGVL--YYLQNNLETADQFLK 1117
Query: 861 KALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSY-L 919
++L+++ R+L + P+ S LAA +C + ++ AE+ Y++A+ + +
Sbjct: 1118 RSLEMRERVLGP---DHPDCAQSLNNLAA-LCNEKKQYDKAEELYERALDIRRRALAPDH 1173
Query: 920 PTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNH--------ETASVLMADLMFRKQ 971
P+ + LA LY G LD + ++ Q TA V +A L + +
Sbjct: 1174 PSLAYTVKHLAILYKKMGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMK 1233
Query: 972 KHEAAINLYHQVLEKAPDNFLVLHKLI-DLLRRSGKLEDIPAFFELAKKVSSR 1023
KH A+ LY + L+ D+ +H + + L+ L FE A ++ R
Sbjct: 1234 KHVEALPLYERALKIYEDSLGRMHPRVGETLKNLAVLSYEGGDFEKAAELYKR 1286
>gi|22749211 transmembrane and tetratricopeptide repeat containing 2
[Homo sapiens]
Length = 836
Score = 43.9 bits (102), Expect = 0.001
Identities = 67/262 (25%), Positives = 113/262 (43%), Gaps = 46/262 (17%)
Query: 706 QTLRDRRLYIRCYRELCEHLPGPH------TSLL--LGDALMSILEPEKALEVYDEAYRQ 757
+T RR +++C E+L PH TS L LG E+AL VY EA ++
Sbjct: 576 RTEEARRTFLKCSEIPDENLKDPHAHKSSVTSCLYNLGKLYHEQGHYEEALSVYKEAIQK 635
Query: 758 NPHD---ASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQDFLCCDL--GKLLLKLKKVN 812
P SL + +G AY++ + EA +Y + + + D + L GKLL + +
Sbjct: 636 MPRQFAPQSLYNMMGEAYMRLSKLPEAEHWYMESLR-SKTDHIPAHLTYGKLLALTGRKS 694
Query: 813 KAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEAVIETLNKALDLQSRILKR 872
+AEK+ +A+E D P+ N C + H + ++E ++R+
Sbjct: 695 EAEKLFLKAIELD-----PTKGN---CYM--------HYGQFLLE--------EARL--- 727
Query: 873 VPLEQPEMIPSQKQL-AASICIQF-AEHYLAEKEYDKAVQSYKDVFSYL-PTDNKVMLEL 929
+E EM +L + + F A H L + ++A + Y D+ + L P ++ L
Sbjct: 728 --IEAAEMAKKAAELDSTEFDVVFNAAHMLRQASLNEAAEKYYDLAARLRPNYPAALMNL 785
Query: 930 AQLYLLQGHLDLCEQHCAILLQ 951
+ L G L E + LQ
Sbjct: 786 GAILHLNGRLQKAEANYLRALQ 807
>gi|167466177 cell division cycle protein 27 isoform 1 [Homo
sapiens]
Length = 830
Score = 42.0 bits (97), Expect = 0.004
Identities = 40/151 (26%), Positives = 64/151 (42%), Gaps = 2/151 (1%)
Query: 677 DVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYRELCEHLPG-PHTSLLLG 735
DVAL++L L A R+ + I+ ++ + P + LLG
Sbjct: 555 DVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLG 614
Query: 736 DALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQ- 794
+ E +KAL + A R NP + +G Y K +++ A +++ A IN Q
Sbjct: 615 HEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQS 674
Query: 795 DFLCCDLGKLLLKLKKVNKAEKVLKQALEHD 825
L C +G + LKK KA L +A+ D
Sbjct: 675 SVLLCHIGVVQHALKKSEKALDTLNKAIVID 705
Score = 33.5 bits (75), Expect = 1.4
Identities = 37/158 (23%), Positives = 66/158 (41%), Gaps = 33/158 (20%)
Query: 309 CGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEAL-------------- 354
C S Q + F +R P+Y + T LG+ F+L ++ +AL
Sbjct: 582 CFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHY 641
Query: 355 -LWYSEAM---KLDKDGMAGL-----------TGIILCHI--LEGHLEEAEYRLEFLKEV 397
WY M K +K +A + + ++LCHI ++ L+++E L+ L +
Sbjct: 642 NAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKA 701
Query: 398 QKSLGKSEVLIFLQA--LLMSRKHKGEEETTALLKEAV 433
K+ + F +A L + K+K + LK+ V
Sbjct: 702 IVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIV 739
>gi|167466175 cell division cycle protein 27 isoform 2 [Homo
sapiens]
Length = 824
Score = 42.0 bits (97), Expect = 0.004
Identities = 40/151 (26%), Positives = 64/151 (42%), Gaps = 2/151 (1%)
Query: 677 DVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYRELCEHLPG-PHTSLLLG 735
DVAL++L L A R+ + I+ ++ + P + LLG
Sbjct: 549 DVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLG 608
Query: 736 DALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQ- 794
+ E +KAL + A R NP + +G Y K +++ A +++ A IN Q
Sbjct: 609 HEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQS 668
Query: 795 DFLCCDLGKLLLKLKKVNKAEKVLKQALEHD 825
L C +G + LKK KA L +A+ D
Sbjct: 669 SVLLCHIGVVQHALKKSEKALDTLNKAIVID 699
Score = 33.5 bits (75), Expect = 1.4
Identities = 37/158 (23%), Positives = 66/158 (41%), Gaps = 33/158 (20%)
Query: 309 CGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEAL-------------- 354
C S Q + F +R P+Y + T LG+ F+L ++ +AL
Sbjct: 576 CFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHY 635
Query: 355 -LWYSEAM---KLDKDGMAGL-----------TGIILCHI--LEGHLEEAEYRLEFLKEV 397
WY M K +K +A + + ++LCHI ++ L+++E L+ L +
Sbjct: 636 NAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKA 695
Query: 398 QKSLGKSEVLIFLQA--LLMSRKHKGEEETTALLKEAV 433
K+ + F +A L + K+K + LK+ V
Sbjct: 696 IVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIV 733
>gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sapiens]
Length = 504
Score = 39.7 bits (91), Expect = 0.019
Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 23/123 (18%)
Query: 1199 DLEKSWLLLADIYCQGSKFDLALELLRRCV---QYNKSC---YKAYEYMGFIMEKEQS-- 1250
D +++ ++ +Y Q +L+L +R C+ Q +K C YK + + ++E +
Sbjct: 220 DNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELI 279
Query: 1251 ----YKDAVTNYKLAWKYSHHANPAIGF-------KLAFNYLKDKKFVEAIEICNDVLRE 1299
Y DA + Y+ K P+I ++ + KD+K VEAI +C++VL+
Sbjct: 280 RDGRYTDATSKYESVMK----TEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQM 335
Query: 1300 HPD 1302
PD
Sbjct: 336 EPD 338
Score = 37.0 bits (84), Expect = 0.13
Identities = 28/113 (24%), Positives = 52/113 (46%), Gaps = 14/113 (12%)
Query: 743 EPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQDFLCCDLG 802
+P +A+ V E + P + + AY+ Y EAI+ YE AQ+ N D
Sbjct: 321 KPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQI---- 376
Query: 803 KLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEAV 855
+ + KA+++LKQ+ + D + + N K ++ K+++K A+
Sbjct: 377 -----REGLEKAQRLLKQSQKRDYYKILGVKRNAKK-----QEIIKAYRKLAL 419
Score = 35.8 bits (81), Expect = 0.28
Identities = 70/350 (20%), Positives = 129/350 (36%), Gaps = 64/350 (18%)
Query: 669 LVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIY----LQTLRDRRL----------- 713
L+L +G +D A + + +L E +E + + +Q LR + L
Sbjct: 114 LLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSGDYTAA 173
Query: 714 --YIRCYRELCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHA 771
++ E+C + L + + EP KA+ A + + +I
Sbjct: 174 IAFLDKILEVC--VWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTL 231
Query: 772 YVKAHQYTEAIEYYEAAQKINGQDFLCCDLGKLLLKLKK-VNKAEKVLKQALEHDIVQDI 830
Y + + ++ K++ C K + KL K + AE++++ D
Sbjct: 232 YYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKY 291
Query: 831 PSMMNDVKCLLLLAKVYKSHKKEAVIETLNK------ALDLQSRILKRVPLEQPEMIPSQ 884
S+M + Y KE + +K A+ + S +L+ +P+ + +
Sbjct: 292 ESVMKTEPSIA----EYTVRSKERICHCFSKDEKPVEAIRVCSEVLQM----EPDNVNAL 343
Query: 885 KQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVM--LELAQLYLLQGHLDLC 942
K A E YL E+ YD+A+Q Y+ + D ++ LE AQ
Sbjct: 344 KDRA--------EAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQR---------- 385
Query: 943 EQHCAILLQTEQNHETASVLMADLMFRKQKHEAAINLYHQV-LEKAPDNF 991
LL+ Q + +L R K + I Y ++ L+ PDNF
Sbjct: 386 ------LLKQSQKRDYYKILGVK---RNAKKQEIIKAYRKLALQWHPDNF 426
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 39.3 bits (90), Expect = 0.025
Identities = 78/395 (19%), Positives = 151/395 (38%), Gaps = 90/395 (22%)
Query: 735 GDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQ 794
G+ +S+ + AL+ Y EA + +PH+ L S AY K Y +A Y + + ++
Sbjct: 11 GNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKA--YEDGCKTVD-- 66
Query: 795 DFLCCDLGK-------LLLKLKKVNKAEKVLKQALEHD-----IVQDIPSM--------- 833
L D GK L L + +A++ ++ L+H+ + + + +M
Sbjct: 67 --LKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEARLAERKF 124
Query: 834 MNDVKCLLLLAKVYKSHK----------KEAVIETLNKALDL-----QSRILKRV----- 873
MN L K+ + +E + + NK DL RI+ +
Sbjct: 125 MNPFNMPNLYQKLESDPRTRTLLSDPTYRELIEQLRNKPSDLGTKLQDPRIMTTLSVLLG 184
Query: 874 --------------------PLEQPEMIPSQKQLAASICIQFAEHYLAEKEY-----DKA 908
P ++ + P ++ L + E L Y D A
Sbjct: 185 VDLGSMDEEEEIATPPPPPPPKKETKPEPMEEDLPENKKQALKEKELGNDAYKKKDFDTA 244
Query: 909 VQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQT-EQNHE------TASV 961
++ Y PT+ + A +Y +G + C + C ++ +N E A
Sbjct: 245 LKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAYA 304
Query: 962 LMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKVS 1021
+ + F+++K++ AI+ Y++ L + H+ D+L++ + E I E ++
Sbjct: 305 RIGNSYFKEEKYKDAIHFYNKSLAE--------HRTPDVLKKCQQAEKILKEQERLAYIN 356
Query: 1022 SRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARK 1056
+ LE +G C+ G +A+K +A K
Sbjct: 357 PDLALE---EKNKGNECFQKGDYPQAMKHYTEAIK 388
>gi|118402596 cell division cycle protein 23 [Homo sapiens]
Length = 597
Score = 38.5 bits (88), Expect = 0.043
Identities = 66/306 (21%), Positives = 123/306 (40%), Gaps = 33/306 (10%)
Query: 675 NVDVALNMLRNILPKQSCYMEAREKMANI-YLQTLRDRRLYIRCYRELCE-HLPGPHTSL 732
++D AL++ + + +E + +N+ Y+++++ Y+ LCE T
Sbjct: 278 DIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLA--HNLCEIDKYRVETCC 335
Query: 733 LLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKIN 792
++G+ + EKA + A + NP + +GH Y++ + AI+ Y A ++N
Sbjct: 336 VIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVN 395
Query: 793 GQDFLC-CDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSHK 851
+D+ LG+ LK ++A H + ND + L+ L + Y
Sbjct: 396 KRDYRAWYGLGQTYEILKMPFYCLYYYRRA--HQL------RPNDSRMLVALGECY---- 443
Query: 852 KEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQ- 910
E LN+ ++ + + + E + K A + Q E A + Y K +Q
Sbjct: 444 -----EKLNQLVEAKKCYWRAYAVGDVEKMALVK--LAKLHEQLTESEQAAQCYIKYIQD 496
Query: 911 --SYKDVFSYLPTDNKVMLELAQLYL---LQGHLDLCEQHCAILLQTEQNHETASVLMAD 965
S ++ +L ++ LAQ Y L C Q C T + E ++L
Sbjct: 497 IYSCGEIVEHL-EESTAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTRE--EGKALLRQI 553
Query: 966 LMFRKQ 971
L R Q
Sbjct: 554 LQLRNQ 559
>gi|224809432 transmembrane and tetratricopeptide repeat containing 3
[Homo sapiens]
Length = 914
Score = 38.1 bits (87), Expect = 0.056
Identities = 60/292 (20%), Positives = 120/292 (41%), Gaps = 26/292 (8%)
Query: 785 YEAAQKINGQDF-LCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLL 843
+ +A K+N + L ++G L K +A K QA H DI + MN +
Sbjct: 435 FMSALKVNKNNAKLWNNVGHALENEKNFERALKYFLQAT-HVQPDDIGAHMN-------V 486
Query: 844 AKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAA------SICIQFAE 897
+ YK+ LN+ + + + L P++IP +K A ++ I A
Sbjct: 487 GRTYKN---------LNRTKEAEESYMMAKSL-MPQIIPGKKYAARIAPNHLNVYINLAN 536
Query: 898 HYLA-EKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNH 956
A E ++A Q Y+ S P + + +L L ++ L+ ++N+
Sbjct: 537 LIRANESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNN 596
Query: 957 ETASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFEL 1016
+A + ++ A+ +++ LE P + L L +++ SG+++ P +
Sbjct: 597 ADLWYNLAIVHIELKEPNEALKNFNRALELNPKHKLALFNSAIVMQESGEVKLRPEARKR 656
Query: 1017 AKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHM 1068
+ PL+ + G+ + NEA ++ KA K +SA++++
Sbjct: 657 LLSYINEEPLDANGYFNLGMLAMDDKKDNEAEIWMKKAIKLQADFRSALFNL 708
Score = 34.7 bits (78), Expect = 0.62
Identities = 69/349 (19%), Positives = 131/349 (37%), Gaps = 30/349 (8%)
Query: 298 HLKKIIVVSRLCGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWY 357
HL I ++ L +++ L + P + G L + N+ +A Y
Sbjct: 527 HLNVYINLANLIRANESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAY 586
Query: 358 SEAMKLDKDGMAGLTGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSR 417
+A++LD++ + + HI L+E L+ + K ++ +F A++M
Sbjct: 587 LKALELDRNNADLWYNLAIVHI---ELKEPNEALKNFNRALELNPKHKLALFNSAIVMQ- 642
Query: 418 KHKGEEETTALLKEAVELHFSSMQGIPLGSE-YF--------EKLDPYFLVCIAKEYLLF 468
E L EA + S + PL + YF +K D + + K L
Sbjct: 643 ----ESGEVKLRPEARKRLLSYINEEPLDANGYFNLGMLAMDDKKDNEAEIWMKKAIKLQ 698
Query: 469 CPKQPRL--PGQIVSPLLKQVAV--ILNPVVKAAPALIDPLYLMAQV--RYYSELENAQS 522
+ L + S K++ IL +++ P I L L + ++ A+
Sbjct: 699 ADFRSALFNLALLYSQTAKELKALPILEELLRYYPDHIKGLILKGDILMNQKKDILGAKK 758
Query: 523 ILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARAL 582
+R LE+DP++V +C +Y + + CL + H Y R L
Sbjct: 759 CFERILEMDPSNVQGKHNLCVVYFEEKDLLKAERCL----LETLALAPHEEY---IQRHL 811
Query: 583 NKAGDYPEAIKTLKMVIKLPALKKEEGRKFLRPSVQPSQRASILLELVE 631
N D + ++ + + EG+K SV+ + S ++V+
Sbjct: 812 NIVRDKISSSSFIEPIFPTSKISSVEGKKIPTESVKEIRGESRQTQIVK 860
>gi|110225358 tetratricopeptide repeat domain 7A [Homo sapiens]
Length = 858
Score = 37.4 bits (85), Expect = 0.096
Identities = 68/302 (22%), Positives = 116/302 (38%), Gaps = 33/302 (10%)
Query: 731 SLLLGDALMSILEPE---KALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEA 787
SL DA + + E KAL+ + A + P D + + Q + A+E +
Sbjct: 498 SLQATDATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQE 557
Query: 788 AQKINGQDFLCCDLGKLLLKLKKVNK-AEKVLKQAL-EHDIVQDIPSMMNDVKC------ 839
A K+ D L LL +K ++ A V+ A+ EH ++ M VK
Sbjct: 558 ALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHP--ENFNLMFTKVKLEQVLKG 615
Query: 840 ----------LLLLAKVYKSHKKEAVIE---TLNKALDLQSRILKRVPLEQPEMIPSQKQ 886
+L L + S + +E + + L ++ + + L S +
Sbjct: 616 PEEALVTCRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSR 675
Query: 887 LAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLD---LCE 943
A+SI E ++E +V + T ++ L+ A+L++ Q HL C
Sbjct: 676 RASSIAASRLEEAMSELTMPSSVLK-QGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCI 734
Query: 944 QHCAILLQTEQNHETASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRR 1003
Q A L T + +A++ K E A LY + L PD ++H L +L R
Sbjct: 735 QEAAGLFPTSHSVLYMRGRLAEV---KGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 791
Query: 1004 SG 1005
G
Sbjct: 792 LG 793
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 36.6 bits (83), Expect = 0.16
Identities = 69/285 (24%), Positives = 107/285 (37%), Gaps = 45/285 (15%)
Query: 743 EPEKALEVYDEAYRQNPHDASLASRIGHAYVK---AHQYTEAIEYYEAAQKINGQDFLCC 799
EPE EV + + H + + Y K H EA++ + A + G+D
Sbjct: 1359 EPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQK 1418
Query: 800 DLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEAVIETL 859
D L K K + +K L+ E D + + + K L K +K+ +E
Sbjct: 1419 DTA-LEQKDKALEPKDKDLE---EKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPK 1474
Query: 860 NKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAE-----------KEYDKA 908
+K L+ + R+L EQ E IP +K A ++ EH E ++ DKA
Sbjct: 1475 DKDLEQKDRVL-----EQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKA 1529
Query: 909 ------VQSYKDVFSYLPTDNKVMLELAQLYLLQGHLD-LCEQHCAILLQTEQNHETASV 961
Q KD S K L Q Y G D EQ+ L + Q E S+
Sbjct: 1530 PEQKHQAQEQKDKVS-----EKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESL 1584
Query: 962 LMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGK 1006
+ D RK K + EK+P+ + + ++ L K
Sbjct: 1585 VQED-KTRKPK---------MLEEKSPEKVKAMEEKLEALLEKTK 1619
>gi|17149828 NMDA receptor regulated 1 [Homo sapiens]
Length = 866
Score = 36.6 bits (83), Expect = 0.16
Identities = 52/240 (21%), Positives = 95/240 (39%), Gaps = 19/240 (7%)
Query: 706 QTLRDRRLYIRCYRELCEHLPGPHTSLLL----GDALMSILEPEKALEVYDEAYRQNPHD 761
Q LR+ LY LC + L + G+ L+ + E A +VY +NP +
Sbjct: 198 QVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPEN 257
Query: 762 ASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQA 821
+ + A +K E ++ YE A + + +L L K ++ L +
Sbjct: 258 WAYYKGLEKA-LKPANMLERLKIYEEAWTKYPRGLV---PRRLPLNFLSGEKFKECLDKF 313
Query: 822 LEHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMI 881
L + + P + N ++ L YK +K A+IE L + LK L P
Sbjct: 314 LRMNFSKGCPPVFNTLRSL------YKDKEKVAIIEELVVGYETS---LKSCRLFNPNDD 364
Query: 882 PSQKQLAASICIQF--AEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHL 939
++ + +Q+ A+HY + A++ PT ++ L A++Y G++
Sbjct: 365 GKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNI 424
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 36.2 bits (82), Expect = 0.21
Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 3/117 (2%)
Query: 881 IPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLD 940
+ SQK L + Y + +YD+A+ Y P + + A Y
Sbjct: 128 VDSQKALVLK---EKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFA 184
Query: 941 LCEQHCAILLQTEQNHETASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKL 997
+ E C + + +++ A F QK E A Y +VLE P+NF ++L
Sbjct: 185 VAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNEL 241
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 36.2 bits (82), Expect = 0.21
Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 3/117 (2%)
Query: 881 IPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLD 940
+ SQK L + Y + +YD+A+ Y P + + A Y
Sbjct: 128 VDSQKALVLK---EKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFA 184
Query: 941 LCEQHCAILLQTEQNHETASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKL 997
+ E C + + +++ A F QK E A Y +VLE P+NF ++L
Sbjct: 185 VAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNEL 241
Score = 32.3 bits (72), Expect = 3.1
Identities = 39/151 (25%), Positives = 68/151 (45%), Gaps = 22/151 (14%)
Query: 164 KKAIEYLEQGIQ-DTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLK-- 220
++AIE +GI D + L +AM ++ Q Y EA + Q + GS+ A +
Sbjct: 299 ERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGT 358
Query: 221 MQLFL-----ARQDWEQT--VEMGHRILEKDESNIDACQILTVHELAREGNMTTVSSLKT 273
+ FL A+QD+E +E G++ + S I EL +G+ V T
Sbjct: 359 ARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIK-------KELIEKGHWDDVFLDST 411
Query: 274 QKATNHVRNLIKALETREPENPSLHLKKIIV 304
Q+ +N++K ++ + LKK+I+
Sbjct: 412 QR-----QNVVKPIDNPPHPGSTKPLKKVII 437
>gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo
sapiens]
Length = 833
Score = 36.2 bits (82), Expect = 0.21
Identities = 52/286 (18%), Positives = 107/286 (37%), Gaps = 60/286 (20%)
Query: 735 GDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQ 794
G+ + + + EKA E Y EA R + IG Y K ++ EA++ +
Sbjct: 500 GNTVFANGDYEKAAEFYKEALRNDSSCTEALYNIGLTYEKLNRLDEALDCF--------- 550
Query: 795 DFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEA 854
LKL + + N + L +A +Y+
Sbjct: 551 -----------LKLHAI---------------------LRNSAEVLYQIANIYE------ 572
Query: 855 VIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKD 914
++E ++A++ +++ +P + P+++ + E Y E + +A Q Y +
Sbjct: 573 LMENPSQAIEWLMQVVSVIPTD-PQVLS-----------KLGELYDREGDKSQAFQYYYE 620
Query: 915 VFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKHE 974
+ Y P + +V+ L Y+ + Q+ + +++A R ++
Sbjct: 621 SYRYFPCNIEVIEWLGAYYIDTQFWEKAIQYFERASLIQPTQVKWQLMVASCFRRSGNYQ 680
Query: 975 AAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKV 1020
A++ Y K P+N L L+ L G L+D + K++
Sbjct: 681 KALDTYKDTHRKFPENVECLRFLVRLCTDLG-LKDAQEYARKLKRL 725
Score = 36.2 bits (82), Expect = 0.21
Identities = 35/158 (22%), Positives = 67/158 (42%), Gaps = 7/158 (4%)
Query: 636 NGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGN-VDVALNMLRNILPKQSCYM 694
NG+ +A + ++ + E + N+ L K N +D AL+ +
Sbjct: 506 NGDYEKAAEFYKEALRNDSSCTE----ALYNIGLTYEKLNRLDEALDCFLKLHAILRNSA 561
Query: 695 EAREKMANIYLQTLRDRRLYIRCYRELCEHLP-GPHTSLLLGDALMSILEPEKALEVYDE 753
E ++ANIY + + + I ++ +P P LG+ + +A + Y E
Sbjct: 562 EVLYQIANIY-ELMENPSQAIEWLMQVVSVIPTDPQVLSKLGELYDREGDKSQAFQYYYE 620
Query: 754 AYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKI 791
+YR P + + +G Y+ + +AI+Y+E A I
Sbjct: 621 SYRYFPCNIEVIEWLGAYYIDTQFWEKAIQYFERASLI 658
>gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo
sapiens]
Length = 824
Score = 36.2 bits (82), Expect = 0.21
Identities = 52/286 (18%), Positives = 107/286 (37%), Gaps = 60/286 (20%)
Query: 735 GDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQ 794
G+ + + + EKA E Y EA R + IG Y K ++ EA++ +
Sbjct: 491 GNTVFANGDYEKAAEFYKEALRNDSSCTEALYNIGLTYEKLNRLDEALDCF--------- 541
Query: 795 DFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEA 854
LKL + + N + L +A +Y+
Sbjct: 542 -----------LKLHAI---------------------LRNSAEVLYQIANIYE------ 563
Query: 855 VIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKD 914
++E ++A++ +++ +P + P+++ + E Y E + +A Q Y +
Sbjct: 564 LMENPSQAIEWLMQVVSVIPTD-PQVLS-----------KLGELYDREGDKSQAFQYYYE 611
Query: 915 VFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKHE 974
+ Y P + +V+ L Y+ + Q+ + +++A R ++
Sbjct: 612 SYRYFPCNIEVIEWLGAYYIDTQFWEKAIQYFERASLIQPTQVKWQLMVASCFRRSGNYQ 671
Query: 975 AAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKV 1020
A++ Y K P+N L L+ L G L+D + K++
Sbjct: 672 KALDTYKDTHRKFPENVECLRFLVRLCTDLG-LKDAQEYARKLKRL 716
Score = 36.2 bits (82), Expect = 0.21
Identities = 35/158 (22%), Positives = 67/158 (42%), Gaps = 7/158 (4%)
Query: 636 NGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGN-VDVALNMLRNILPKQSCYM 694
NG+ +A + ++ + E + N+ L K N +D AL+ +
Sbjct: 497 NGDYEKAAEFYKEALRNDSSCTE----ALYNIGLTYEKLNRLDEALDCFLKLHAILRNSA 552
Query: 695 EAREKMANIYLQTLRDRRLYIRCYRELCEHLP-GPHTSLLLGDALMSILEPEKALEVYDE 753
E ++ANIY + + + I ++ +P P LG+ + +A + Y E
Sbjct: 553 EVLYQIANIY-ELMENPSQAIEWLMQVVSVIPTDPQVLSKLGELYDREGDKSQAFQYYYE 611
Query: 754 AYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKI 791
+YR P + + +G Y+ + +AI+Y+E A I
Sbjct: 612 SYRYFPCNIEVIEWLGAYYIDTQFWEKAIQYFERASLI 649
>gi|15619013 43 kD receptor-associated protein of the synapse
isoform 1 [Homo sapiens]
Length = 412
Score = 35.0 bits (79), Expect = 0.48
Identities = 54/223 (24%), Positives = 92/223 (41%), Gaps = 48/223 (21%)
Query: 718 YRELCEHLPGPHT--------SLLLGDALMSILEPEKALEVYDEA--YRQNPHDASLASR 767
Y + C LPG SL +G+A + + +KALE +++A Y N DA L R
Sbjct: 105 YCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECR 164
Query: 768 I----GHAYVKAHQYTEAIEY-YEAAQKING------------QDFLCCDLGKLLLKL-K 809
+ G Y + Y +A+ + +AA+ +N + +LL +L
Sbjct: 165 VCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGS 224
Query: 810 KVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSH-KKEAVIETLNKALDLQSR 868
+ E+ +K AL+H D P CLL A +++S E + A+ + +
Sbjct: 225 AMECCEESMKIALQHG---DRPL---QALCLLCFADIHRSRGDLETAFPRYDSAMSIMTE 278
Query: 869 ILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQS 911
I R+ Q Q + A+ ++A K DKA+ +
Sbjct: 279 IGNRL---------GQVQALLGV----AKCWVARKALDKALDA 308
>gi|209976994 adenylate cyclase 10 [Homo sapiens]
Length = 1610
Score = 34.7 bits (78), Expect = 0.62
Identities = 38/152 (25%), Positives = 65/152 (42%), Gaps = 22/152 (14%)
Query: 857 ETLNKALDLQSRILKRVPLEQPEMIPSQ----KQLAASICIQFAEHYLAEKEYDKAVQSY 912
E K L+ +L ++ ++IP + +++ + + A H+LA E DKA+ +
Sbjct: 1029 EIREKILNFFDHVLTKMKTSDEDIIPLESCQCEEILEIVILPLAHHFLALGENDKALYYF 1088
Query: 913 KDVFS-YLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADLMFRKQ 971
++ S YL + M A +YL +G LL+T + ++ S F
Sbjct: 1089 LEIASAYLIFCDNYM---AYMYLNEGQK---------LLKTLKKDKSWSQTFESATFYSL 1136
Query: 972 KHEAAINLYHQVLEKAPDNFLVLHKLIDLLRR 1003
K E N+ VL K +L K + LL R
Sbjct: 1137 KGEVCFNMGQIVLAKK-----MLRKALKLLNR 1163
>gi|60685231 tetratricopeptide repeat domain 7B [Homo sapiens]
Length = 843
Score = 34.7 bits (78), Expect = 0.62
Identities = 21/94 (22%), Positives = 45/94 (47%)
Query: 907 KAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADL 966
KA+ +++ S PTD++ LA + + + LQ + + + L+A L
Sbjct: 499 KALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALL 558
Query: 967 MFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDL 1000
+ ++ + A+N+ L + P+NF++L + L
Sbjct: 559 LSAQKHYHDALNIIDMALSEYPENFILLFSKVKL 592
>gi|4503729 FK506 binding protein 52 [Homo sapiens]
Length = 459
Score = 33.9 bits (76), Expect = 1.1
Identities = 51/204 (25%), Positives = 79/204 (38%), Gaps = 43/204 (21%)
Query: 1109 EKLLREFYPHSDSSQTQLRLLQGLCRLATREKANMEAALGSFIQIAQAEKDSVPALLALA 1168
E L +Y Q +LR G E N++ G I + EK +++ L
Sbjct: 171 EVALEGYYKDKLFDQRELRFEIG-------EGENLDLPYGLERAIQRMEKGE-HSIVYLK 222
Query: 1169 QAYVFLK------QIP-----KARMQLKRL--AKTPWVLSEAEDLEKSWLLL--ADIYCQ 1213
+Y F QIP K + LK AK W ++ E LE+S ++ +Y +
Sbjct: 223 PSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFK 282
Query: 1214 GSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYKLAWKYSHHANPAIG 1273
K+ AL ++ V + +E E S+ + A + + H N
Sbjct: 283 EGKYKQALLQYKKIVSW--------------LEYESSFSNEEAQKAQALRLASHLN---- 324
Query: 1274 FKLAFNYLKDKKFVEAIEICNDVL 1297
LA +LK + F AIE CN L
Sbjct: 325 --LAMCHLKLQAFSAAIESCNKAL 346
>gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 33.5 bits (75), Expect = 1.4
Identities = 61/310 (19%), Positives = 118/310 (38%), Gaps = 64/310 (20%)
Query: 772 YVKAHQYTEAIEYYEAAQKINGQD---------FLCCDLGKLLLKLKKVNKAEKVLKQAL 822
YV++ E I+YYE+ KI ++ F C G + KL K+ A
Sbjct: 885 YVESDLPQEVIKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSA-------- 936
Query: 823 EHDIVQDIPSMMNDVKCLLLLAKVYKS-----HKKEAVIETLNKALDLQSRILKRVPLEQ 877
MND++ ++LL ++ + H + +N+ALD + I K
Sbjct: 937 -----------MNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHK------ 979
Query: 878 PEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQG 937
+ + AE Y +K+ A+ +Y PTD + ++Y +
Sbjct: 980 ------YNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITN 1033
Query: 938 HLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKH--------EAAINLYHQVLEKAPD 989
+ + + + T ++L L + + ++ A +N+ HQ +A
Sbjct: 1034 KVLAIDDFSKCIFYDPK--RTDALLKRGLFYCENENWFAAIEDFTALLNIDHQ-NSQARG 1090
Query: 990 NFLVLHKLIDLLRRSGKLEDIPAFFELAKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALK 1049
+L++ K DL + + I E+ K +S P++ Y +C + + E L
Sbjct: 1091 QYLLMMKYYDLAKFT-----IYQIAEMDKGLSELSPMQQALIYS---FCENHDKAIEVLD 1142
Query: 1050 FLNKARKDST 1059
++ R + T
Sbjct: 1143 GISWNRAEMT 1152
>gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 33.5 bits (75), Expect = 1.4
Identities = 61/310 (19%), Positives = 118/310 (38%), Gaps = 64/310 (20%)
Query: 772 YVKAHQYTEAIEYYEAAQKINGQD---------FLCCDLGKLLLKLKKVNKAEKVLKQAL 822
YV++ E I+YYE+ KI ++ F C G + KL K+ A
Sbjct: 885 YVESDLPQEVIKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSA-------- 936
Query: 823 EHDIVQDIPSMMNDVKCLLLLAKVYKS-----HKKEAVIETLNKALDLQSRILKRVPLEQ 877
MND++ ++LL ++ + H + +N+ALD + I K
Sbjct: 937 -----------MNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHK------ 979
Query: 878 PEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQG 937
+ + AE Y +K+ A+ +Y PTD + ++Y +
Sbjct: 980 ------YNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITN 1033
Query: 938 HLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKH--------EAAINLYHQVLEKAPD 989
+ + + + T ++L L + + ++ A +N+ HQ +A
Sbjct: 1034 KVLAIDDFSKCIFYDPK--RTDALLKRGLFYCENENWFAAIEDFTALLNIDHQ-NSQARG 1090
Query: 990 NFLVLHKLIDLLRRSGKLEDIPAFFELAKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALK 1049
+L++ K DL + + I E+ K +S P++ Y +C + + E L
Sbjct: 1091 QYLLMMKYYDLAKFT-----IYQIAEMDKGLSELSPMQQALIYS---FCENHDKAIEVLD 1142
Query: 1050 FLNKARKDST 1059
++ R + T
Sbjct: 1143 GISWNRAEMT 1152
>gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Homo
sapiens]
Length = 1614
Score = 33.5 bits (75), Expect = 1.4
Identities = 61/310 (19%), Positives = 118/310 (38%), Gaps = 64/310 (20%)
Query: 772 YVKAHQYTEAIEYYEAAQKINGQD---------FLCCDLGKLLLKLKKVNKAEKVLKQAL 822
YV++ E I+YYE+ KI ++ F C G + KL K+ A
Sbjct: 885 YVESDLPQEVIKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSA-------- 936
Query: 823 EHDIVQDIPSMMNDVKCLLLLAKVYKS-----HKKEAVIETLNKALDLQSRILKRVPLEQ 877
MND++ ++LL ++ + H + +N+ALD + I K
Sbjct: 937 -----------MNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHK------ 979
Query: 878 PEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQG 937
+ + AE Y +K+ A+ +Y PTD + ++Y +
Sbjct: 980 ------YNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITN 1033
Query: 938 HLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKH--------EAAINLYHQVLEKAPD 989
+ + + + T ++L L + + ++ A +N+ HQ +A
Sbjct: 1034 KVLAIDDFSKCIFYDPK--RTDALLKRGLFYCENENWFAAIEDFTALLNIDHQ-NSQARG 1090
Query: 990 NFLVLHKLIDLLRRSGKLEDIPAFFELAKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALK 1049
+L++ K DL + + I E+ K +S P++ Y +C + + E L
Sbjct: 1091 QYLLMMKYYDLAKFT-----IYQIAEMDKGLSELSPMQQALIYS---FCENHDKAIEVLD 1142
Query: 1050 FLNKARKDST 1059
++ R + T
Sbjct: 1143 GISWNRAEMT 1152
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,106,319
Number of Sequences: 37866
Number of extensions: 1983346
Number of successful extensions: 6074
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 5789
Number of HSP's gapped (non-prelim): 286
length of query: 1320
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1206
effective length of database: 13,930,794
effective search space: 16800537564
effective search space used: 16800537564
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.