Guide to the Human Genome
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Search of human proteins with 157426866

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157426866 zinc finger, FYVE domain containing 16 [Homo
sapiens]
         (1539 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens]   3070   0.0  
gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens]   3070   0.0  
gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Hom...   714   0.0  
gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Hom...   583   e-166
gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo...   135   2e-31
gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens]    86   4e-16
gi|217272865 myotubularin related protein 4 [Homo sapiens]             75   6e-13
gi|194018497 FYVE, RhoGEF and PH domain containing 5 [Homo sapiens]    75   6e-13
gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens]      75   6e-13
gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su...    72   4e-12
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ...    71   7e-12
gi|198041928 FYVE, RhoGEF and PH domain containing 4 [Homo sapiens]    71   9e-12
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi...    70   1e-11
gi|13375827 phafin 2 [Homo sapiens]                                    70   2e-11
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]    67   1e-10
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]    67   1e-10
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa...    67   1e-10
gi|24797153 faciogenital dysplasia protein [Homo sapiens]              67   1e-10
gi|189217917 FYVE, RhoGEF and PH domain containing 2 [Homo sapiens]    67   1e-10
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap...    65   5e-10
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap...    65   5e-10
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap...    65   5e-10
gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens]      65   7e-10
gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens]      65   7e-10
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             64   1e-09
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    62   4e-09
gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Ho...    62   4e-09
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho...    62   4e-09
gi|153791377 apoptosis-inducing protein D [Homo sapiens]               61   7e-09
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]    60   2e-08

>gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens]
          Length = 1539

 Score = 3070 bits (7959), Expect = 0.0
 Identities = 1539/1539 (100%), Positives = 1539/1539 (100%)

Query: 1    MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 60
            MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ
Sbjct: 1    MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 60

Query: 61   ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 120
            ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG
Sbjct: 61   ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 120

Query: 121  RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH 180
            RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH
Sbjct: 121  RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH 180

Query: 181  DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV 240
            DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV
Sbjct: 181  DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV 240

Query: 241  DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS 300
            DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS
Sbjct: 241  DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS 300

Query: 301  ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS 360
            ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS
Sbjct: 301  ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS 360

Query: 361  SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS 420
            SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS
Sbjct: 361  SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS 420

Query: 421  VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES 480
            VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES
Sbjct: 421  VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES 480

Query: 481  QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ 540
            QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ
Sbjct: 481  QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ 540

Query: 541  YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD 600
            YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD
Sbjct: 541  YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD 600

Query: 601  KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR 660
            KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR
Sbjct: 601  KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR 660

Query: 661  SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT 720
            SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT
Sbjct: 661  SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT 720

Query: 721  ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC 780
            ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC
Sbjct: 721  ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC 780

Query: 781  CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT 840
            CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT
Sbjct: 781  CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT 840

Query: 841  SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS 900
            SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS
Sbjct: 841  SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS 900

Query: 901  PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP 960
            PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP
Sbjct: 901  PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP 960

Query: 961  TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED 1020
            TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED
Sbjct: 961  TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED 1020

Query: 1021 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK 1080
            SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK
Sbjct: 1021 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK 1080

Query: 1081 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT 1140
            YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT
Sbjct: 1081 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT 1140

Query: 1141 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE 1200
            ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE
Sbjct: 1141 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE 1200

Query: 1201 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR 1260
            YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR
Sbjct: 1201 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR 1260

Query: 1261 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF 1320
            KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF
Sbjct: 1261 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF 1320

Query: 1321 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE 1380
            VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE
Sbjct: 1321 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE 1380

Query: 1381 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD 1440
            YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD
Sbjct: 1381 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD 1440

Query: 1441 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP 1500
            LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP
Sbjct: 1441 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP 1500

Query: 1501 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF 1539
            QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF
Sbjct: 1501 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF 1539


>gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens]
          Length = 1539

 Score = 3070 bits (7959), Expect = 0.0
 Identities = 1539/1539 (100%), Positives = 1539/1539 (100%)

Query: 1    MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 60
            MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ
Sbjct: 1    MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 60

Query: 61   ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 120
            ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG
Sbjct: 61   ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 120

Query: 121  RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH 180
            RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH
Sbjct: 121  RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH 180

Query: 181  DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV 240
            DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV
Sbjct: 181  DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV 240

Query: 241  DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS 300
            DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS
Sbjct: 241  DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS 300

Query: 301  ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS 360
            ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS
Sbjct: 301  ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS 360

Query: 361  SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS 420
            SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS
Sbjct: 361  SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS 420

Query: 421  VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES 480
            VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES
Sbjct: 421  VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES 480

Query: 481  QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ 540
            QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ
Sbjct: 481  QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ 540

Query: 541  YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD 600
            YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD
Sbjct: 541  YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD 600

Query: 601  KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR 660
            KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR
Sbjct: 601  KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR 660

Query: 661  SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT 720
            SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT
Sbjct: 661  SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT 720

Query: 721  ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC 780
            ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC
Sbjct: 721  ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC 780

Query: 781  CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT 840
            CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT
Sbjct: 781  CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT 840

Query: 841  SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS 900
            SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS
Sbjct: 841  SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS 900

Query: 901  PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP 960
            PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP
Sbjct: 901  PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP 960

Query: 961  TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED 1020
            TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED
Sbjct: 961  TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED 1020

Query: 1021 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK 1080
            SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK
Sbjct: 1021 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK 1080

Query: 1081 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT 1140
            YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT
Sbjct: 1081 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT 1140

Query: 1141 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE 1200
            ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE
Sbjct: 1141 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE 1200

Query: 1201 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR 1260
            YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR
Sbjct: 1201 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR 1260

Query: 1261 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF 1320
            KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF
Sbjct: 1261 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF 1320

Query: 1321 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE 1380
            VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE
Sbjct: 1321 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE 1380

Query: 1381 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD 1440
            YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD
Sbjct: 1381 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD 1440

Query: 1441 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP 1500
            LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP
Sbjct: 1441 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP 1500

Query: 1501 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF 1539
            QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF
Sbjct: 1501 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF 1539


>gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Homo
            sapiens]
          Length = 1425

 Score =  714 bits (1842), Expect = 0.0
 Identities = 538/1598 (33%), Positives = 799/1598 (50%), Gaps = 234/1598 (14%)

Query: 1    MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 60
            M++YF+A   +LDK+LD+FEQN DE                +VSS L  ++   +L    
Sbjct: 1    MENYFQAEAYNLDKVLDEFEQNEDE----------------TVSSTLLDTKWNKILDPP- 43

Query: 61   ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 120
                   S   S+    +S+NE  +    S +++  +    L  S    T +E       
Sbjct: 44   -------SHRLSFNPTLASVNESAV----SNESQPQLKVFSLAHSAPLTTEEE------D 86

Query: 121  RCSK-PICDLISDMGNL---VHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTP--- 173
             C+    C+L  ++  +    +A   ++ IK+    D + +A  +      +++  P   
Sbjct: 87   HCANGQDCNLNPEIATMWIDENAVAEDQLIKRNYSWDDQCSAVEVGEKKCGNLACLPDEK 146

Query: 174  --CVSSTDHDSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKK 231
               V +  H+ D  R  QND+           +      +D     +  +S + N   +K
Sbjct: 147  NVLVVAVMHNCDK-RTLQNDLQDCNNYNSQSLMDAFSCSLDNENRQTDQFSFSINESTEK 205

Query: 232  IFNQLESIVDFNMSSALTRQSSKMFH-AKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAA 290
              N  + +   N      R  + +   + D L     P   LKD G +  +  ++ IT+ 
Sbjct: 206  DMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASVCSP-SQLKDDGSIGRDPSMSAITSL 264

Query: 291  ---ECLKEEGKTSALTCSLPKN----EDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQ 343
                 +  +G          +N    EDL    S+ R +      FS   +  ++K+   
Sbjct: 265  TVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSPRTDLGSPNSFSHMSEGILMKKEPA 324

Query: 344  EDSKSLDLKDNDVIQDSSSALHVSSK-DVPSSLSCLPASGSMCGSLIESKARGDFLPQHE 402
            E+S + +           S L +  K D+P+              L+ ++ R D    +E
Sbjct: 325  EESTTEE--------SLRSGLPLLLKPDMPNGSGRNNDCERCSDCLVPNEVRADENEGYE 376

Query: 403  HKDNIQDAVTIHEEIQNSVVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQT- 461
            H++ +        E  N      E F E+  +   K   +        M D +++ ++  
Sbjct: 377  HEETLGTT-----EFLNMT----EHFSESQDMTNWKLTKL------NEMNDSQVNEEKEK 421

Query: 462  ---VIRAESLDGGDTSSTVVESQEGLS--GTHVPESSDC-CEGFINTFSSNDMDGQDLDY 515
               + + E  +G      V  +  GL   GT + ES +C     I+T ++N +      Y
Sbjct: 422  FLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDSY 481

Query: 516  FNIDEGAKSGPLISDAELDAFLTEQYLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNIN 575
               D G    P    ++ D+ +TE           E+ + +SKS+              +
Sbjct: 482  GMQDPGVSFVPKTLPSKEDS-VTE-----------EKEIEESKSEC------------YS 517

Query: 576  NIYFNAEAGAIGESHGINIICETVD--KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQ 633
            NIY         E  G+ ++  T D  K+N + N  S      +P   G  + K      
Sbjct: 518  NIY-EQRGNEATEGSGL-LLNSTGDLMKKNYLHNFCS-----QVPSVLGQSSPKV----- 565

Query: 634  LSVSDINSQSV--GGARPKQLFSLPSRT-RSSKDLNKPDVPDTIESEPSTADTVVPITCA 690
              V+ + S SV  GGARPKQ  +L  +  +   D  + D P    +     + ++     
Sbjct: 566  --VASLPSISVPFGGARPKQPSNLKLQIPKPLSDHLQNDFPANSGNNTKNKNDILGKAKL 623

Query: 691  IDSTADPQVSFN-SNYIDIESNSEGGSSFVT--------ANEDSVPENTCKEG------- 734
             +++A    S +  N  ++++N E   S+          A     P+N  + G       
Sbjct: 624  GENSATNVCSPSLGNISNVDTNGEHLESYEAEISTRPCLALAPDSPDNDLRAGQFGISAR 683

Query: 735  ---LVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLE 791
                 LG+  P WVPDS+APNCM C+ +FTFTKRRHHCRACGKVFC  CC+ KCKL Y++
Sbjct: 684  KPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMD 743

Query: 792  -KEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDE-CTTVQPPQENQTSSIPSPATL 849
             KEARVCV+C+  +  AQA+E MMS +  +   N+  E C+T+ P Q+ Q S        
Sbjct: 744  RKEARVCVICHSVLMNAQAWENMMSASSQSPNPNNPAEYCSTIPPLQQAQASG------- 796

Query: 850  PVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFSPLSPDVPMT 909
               AL  P                                              P V + 
Sbjct: 797  ---ALSSP---------------------------------------------PPTVMVP 808

Query: 910  VNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLPTSGSFTLDD 969
            V  + H     V +P  +      + I+  P  +V    KL+MN       TS + TL  
Sbjct: 809  VGVLKHP-GAEVAQPREQRRVWFADGIL--PNGEVADAAKLTMNG------TSSAGTL-- 857

Query: 970  DVFAETEEPSSPTGVLVNSNLPIASISDYRL----LCDINKYVCNKISLLPNDEDSLPPL 1025
               A + +P  P      +  P+ + +D  L    +  +   V + ++L+P  ED LPP+
Sbjct: 858  ---AVSHDPVKPV-----TTSPLPAETDICLFSGSITQVGSPVGSAMNLIP--EDGLPPI 907

Query: 1026 LVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDKYWYFS 1085
            L+++G KG    VEE PS   ++  LE  G  P+ FVLNANLL  VK + Y + K W F+
Sbjct: 908  LISTGVKGDY-AVEEKPSQISVMQQLEDGGPDPLVFVLNANLLSMVKIVNYVNRKCWCFT 966

Query: 1086 TNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFTESFLS 1145
            T G+H +GQ+EI+ILL CLP+E  +PKDIF  F+ +Y+DAL G  + NL +  F++SFL 
Sbjct: 967  TKGMHAVGQSEIVILLQCLPDEKCLPKDIFNHFVQLYRDALAGNVVSNLGHSFFSQSFLG 1026

Query: 1146 SKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAEYKAYP 1205
            SK+HGGFL++T T+Q L DL LP+ P+L GILIQK E PWAKVFP+RLMLRLGAEY+ YP
Sbjct: 1027 SKEHGGFLYVTSTYQSLQDLVLPTPPYLFGILIQKWETPWAKVFPIRLMLRLGAEYRLYP 1086

Query: 1206 APLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPRKKYSD 1265
             PL S+R RKPLFGE GHTIMNLL D RNYQYTL  +  L++ ME+ K+ IKIP  +Y++
Sbjct: 1087 CPLFSVRFRKPLFGETGHTIMNLLADFRNYQYTLPVVQGLVVDMEVRKTSIKIPSNRYNE 1146

Query: 1266 VMKVLNSSNEHVISIGASFSTEADSHLVCIQN-DGIYETQANSATGHPRKVTGASFVVFN 1324
            +MK +N SNEHV++ GA F+ +ADSHLVC+QN DG Y+TQA S    PRKVTGASF VF+
Sbjct: 1147 MMKAMNKSNEHVLAGGACFNEKADSHLVCVQNDDGNYQTQAISIHNQPRKVTGASFFVFS 1206

Query: 1325 GALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLREYVDI 1384
            GALK+SSG+LAKSSIVEDG+MVQIT E M+ LR ALRE KDF ITCGK DA + +E++ I
Sbjct: 1207 GALKSSSGYLAKSSIVEDGVMVQITAENMDSLRQALREMKDFTITCGKADAEEPQEHIHI 1266

Query: 1385 CWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQDLSIL 1444
             WVD ++  +KGV+S +DG S++   + KI   ++++ + K+++ TEVF+   D   + L
Sbjct: 1267 QWVDDDKNVSKGVVSPIDGKSMETITNVKIFHGSEYKANGKVIRWTEVFFLENDDQHNCL 1326

Query: 1445 S---TSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLPQ 1501
            S      +  + +A A   ALCPHLK LK +GM K+GLRV++D+D V +QAGS GQ LP 
Sbjct: 1327 SDPADHSRLTEHVAKAFCLALCPHLKLLKEDGMTKLGLRVTLDSDQVGYQAGSNGQPLPS 1386

Query: 1502 HYLNDLDSALIPVIHGGTSN-SSLPLEIELVFFIIEHL 1538
             Y+NDLDSAL+PVIHGG    S  P+ +EL+F+I+E++
Sbjct: 1387 QYMNDLDSALVPVIHGGACQLSEGPVVMELIFYILENI 1424


>gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Homo
            sapiens]
          Length = 1366

 Score =  583 bits (1504), Expect = e-166
 Identities = 311/608 (51%), Positives = 419/608 (68%), Gaps = 28/608 (4%)

Query: 940  PISQVPSVEKLSMNTGNEGLPTSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYR 999
            P  +V    KL+MN       TS + TL     A + +P  P      +  P+ + +D  
Sbjct: 777  PNGEVADAAKLTMNG------TSSAGTL-----AVSHDPVKPV-----TTSPLPAETDIC 820

Query: 1000 L----LCDINKYVCNKISLLPNDEDSLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEG 1055
            L    +  +   V + ++L+P  ED LPP+L+++G KG    VEE PS   ++  LE  G
Sbjct: 821  LFSGSITQVGSPVGSAMNLIP--EDGLPPILISTGVKGDY-AVEEKPSQISVMQQLEDGG 877

Query: 1056 FHPVTFVLNANLLVNVKFIFYSSDKYWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIF 1115
              P+ FVLNANLL  VK + Y + K W F+T G+H +GQ+EI+ILL CLP+E  +PKDIF
Sbjct: 878  PDPLVFVLNANLLSMVKIVNYVNRKCWCFTTKGMHAVGQSEIVILLQCLPDEKCLPKDIF 937

Query: 1116 RLFITIYKDALKGKYIENLDNITFTESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCG 1175
              F+ +Y+DAL G  + NL +  F++SFL SK+HGGFL++T T+Q L DL LP+ P+L G
Sbjct: 938  NHFVQLYRDALAGNVVSNLGHSFFSQSFLGSKEHGGFLYVTSTYQSLQDLVLPTPPYLFG 997

Query: 1176 ILIQKLEIPWAKVFPMRLMLRLGAEYKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNY 1235
            ILIQK E PWAKVFP+RLMLRLGAEY+ YP PL S+R RKPLFGE GHTIMNLL D RNY
Sbjct: 998  ILIQKWETPWAKVFPIRLMLRLGAEYRLYPCPLFSVRFRKPLFGETGHTIMNLLADFRNY 1057

Query: 1236 QYTLHNIDQLLIHMEMGKSCIKIPRKKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCI 1295
            QYTL  +  L++ ME+ K+ IKIP  +Y+++MK +N SNEHV++ GA F+ +ADSHLVC+
Sbjct: 1058 QYTLPVVQGLVVDMEVRKTSIKIPSNRYNEMMKAMNKSNEHVLAGGACFNEKADSHLVCV 1117

Query: 1296 QN-DGIYETQANSATGHPRKVTGASFVVFNGALKTSSGFLAKSSIVEDGLMVQITPETMN 1354
            QN DG Y+TQA S    PRKVTGASF VF+GALK+SSG+LAKSSIVEDG+MVQIT E M+
Sbjct: 1118 QNDDGNYQTQAISIHNQPRKVTGASFFVFSGALKSSSGYLAKSSIVEDGVMVQITAENMD 1177

Query: 1355 GLRLALREQKDFKITCGKVDAVDLREYVDICWVDAEEKGNKGVISSVDGISLQGFPSEKI 1414
             LR ALRE KDF ITCGK DA + +E++ I WVD ++  +KGV+S +DG S++   + KI
Sbjct: 1178 SLRQALREMKDFTITCGKADAEEPQEHIHIQWVDDDKNVSKGVVSPIDGKSMETITNVKI 1237

Query: 1415 KLEADFETDEKIVKCTEVFYFLKDQDLSILS---TSYQFAKEIAMACSAALCPHLKTLKS 1471
               ++++ + K+++ TEVF+   D   + LS      +  + +A A   ALCPHLK LK 
Sbjct: 1238 FHGSEYKANGKVIRWTEVFFLENDDQHNCLSDPADHSRLTEHVAKAFCLALCPHLKLLKE 1297

Query: 1472 NGMNKIGLRVSIDTDMVEFQAGSEGQLLPQHYLNDLDSALIPVIHGGTSN-SSLPLEIEL 1530
            +GM K+GLRV++D+D V +QAGS GQ LP  Y+NDLDSAL+PVIHGG    S  P+ +EL
Sbjct: 1298 DGMTKLGLRVTLDSDQVGYQAGSNGQPLPSQYMNDLDSALVPVIHGGACQLSEGPVVMEL 1357

Query: 1531 VFFIIEHL 1538
            +F+I+E++
Sbjct: 1358 IFYILENI 1365



 Score =  155 bits (392), Expect = 3e-37
 Identities = 232/960 (24%), Positives = 375/960 (39%), Gaps = 209/960 (21%)

Query: 1   MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 60
           M++YF+A   +LDK+LD+FEQN DE                +VSS L  ++   +L    
Sbjct: 1   MENYFQAEAYNLDKVLDEFEQNEDE----------------TVSSTLLDTKWNKILDPP- 43

Query: 61  ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 120
                  S   S+    +S+NE  +    S +++  +    L  S    T +E       
Sbjct: 44  -------SHRLSFNPTLASVNESAV----SNESQPQLKVFSLAHSAPLTTEEE------D 86

Query: 121 RCSK-PICDLISDMGNL---VHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTP--- 173
            C+    C+L  ++  +    +A   ++ IK+    D + +A  +      +++  P   
Sbjct: 87  HCANGQDCNLNPEIATMWIDENAVAEDQLIKRNYSWDDQCSAVEVGEKKCGNLACLPDEK 146

Query: 174 --CVSSTDHDSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKK 231
              V +  H+ D  R  QND+           +      +D     +  +S + N   +K
Sbjct: 147 NVLVVAVMHNCDK-RTLQNDLQDCNNYNSQSLMDAFSCSLDNENRQTDQFSFSINESTEK 205

Query: 232 IFNQLESIVDFNMSSALTRQSSKMFH-AKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAA 290
             N  + +   N      R  + +   + D L     P   LKD G +  +  ++ IT+ 
Sbjct: 206 DMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASVCSP-SQLKDDGSIGRDPSMSAITSL 264

Query: 291 ---ECLKEEGKTSALTCSLPKN----EDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQ 343
                +  +G          +N    EDL    S+ R +      FS   +  ++K+   
Sbjct: 265 TVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSPRTDLGSPNSFSHMSEGILMKKEPA 324

Query: 344 EDSKSLDLKDNDVIQDSSSALHVSSK-DVPSSLSCLPASGSMCGSLIESKARGDFLPQHE 402
           E+S + +           S L +  K D+P+              L+ ++ R D    +E
Sbjct: 325 EESTTEE--------SLRSGLPLLLKPDMPNGSGRNNDCERCSDCLVPNEVRADENEGYE 376

Query: 403 HKDNIQDAVTIHEEIQNSVVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQT- 461
           H++ +        E  N      E F E+  +   K   +        M D +++ ++  
Sbjct: 377 HEETLGTT-----EFLNMT----EHFSESQDMTNWKLTKL------NEMNDSQVNEEKEK 421

Query: 462 ---VIRAESLDGGDTSSTVVESQEGLS--GTHVPESSDC-CEGFINTFSSNDMDGQDLDY 515
              + + E  +G      V  +  GL   GT + ES +C     I+T ++N +      Y
Sbjct: 422 FLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDSY 481

Query: 516 FNIDEGAKSGPLISDAELDAFLTEQYLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNIN 575
              D G    P    ++ D+ +TE           E+ + +SKS+              +
Sbjct: 482 GMQDPGVSFVPKTLPSKEDS-VTE-----------EKEIEESKSEC------------YS 517

Query: 576 NIYFNAEAGAIGESHGINIICETVD--KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQ 633
           NIY         E  G+ ++  T D  K+N + N  S      +P   G  + K      
Sbjct: 518 NIY-EQRGNEATEGSGL-LLNSTGDLMKKNYLHNFCS-----QVPSVLGQSSPKV----- 565

Query: 634 LSVSDINSQSV--GGARPKQLFSLPSRT-RSSKDLNKPDVPDTIESEPSTADTVVPITCA 690
             V+ + S SV  GGARPKQ  +L  +  +   D  + D P    +     + ++     
Sbjct: 566 --VASLPSISVPFGGARPKQPSNLKLQIPKPLSDHLQNDFPANSGNNTKNKNDILGKAKL 623

Query: 691 IDSTADPQVSFN-SNYIDIESNSEGGSSFVT--------ANEDSVPENTCKEG------- 734
            +++A    S +  N  ++++N E   S+          A     P+N  + G       
Sbjct: 624 GENSATNVCSPSLGNISNVDTNGEHLESYEAEISTRPCLALAPDSPDNDLRAGQFGISAR 683

Query: 735 ---LVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLE 791
                LG+  P WVPDS+APNCM C+ +FTFTKRRHHCRACGKVFC  CC+ KCKL Y++
Sbjct: 684 KPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMD 743

Query: 792 -KEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQTSSIPSPATLP 850
            KEARVCV+C                        HS      QP                
Sbjct: 744 RKEARVCVIC------------------------HSVLMNVAQP---------------- 763

Query: 851 VSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKL------SSGSKRCSEDFSPLSP 904
                         +EQ+RVWFADGILPNGEVAD  KL      S+G+   S D  P+ P
Sbjct: 764 --------------REQRRVWFADGILPNGEVADAAKLTMNGTSSAGTLAVSHD--PVKP 807


>gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo
           sapiens]
          Length = 762

 Score =  135 bits (341), Expect = 2e-31
 Identities = 202/854 (23%), Positives = 342/854 (40%), Gaps = 147/854 (17%)

Query: 1   MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 60
           M++YF+A   +LDK+LD+FEQN DE                +VSS L  ++   +L    
Sbjct: 1   MENYFQAEAYNLDKVLDEFEQNEDE----------------TVSSTLLDTKWNKILDPP- 43

Query: 61  ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 120
                  S   S+    +S+NE  +    S +++  +    L  S    T +E       
Sbjct: 44  -------SHRLSFNPTLASVNESAV----SNESQPQLKVFSLAHSAPLTTEEE------D 86

Query: 121 RCSK-PICDLISDMGNL---VHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTP--- 173
            C+    C+L  ++  +    +A   ++ IK+    D + +A  +      +++  P   
Sbjct: 87  HCANGQDCNLNPEIATMWIDENAVAEDQLIKRNYSWDDQCSAVEVGEKKCGNLACLPDEK 146

Query: 174 --CVSSTDHDSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKK 231
              V +  H+ D  R  QND+           +      +D     +  +S + N   +K
Sbjct: 147 NVLVVAVMHNCDK-RTLQNDLQDCNNYNSQSLMDAFSCSLDNENRQTDQFSFSINESTEK 205

Query: 232 IFNQLESIVDFNMSSALTRQSSKMFH-AKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAA 290
             N  + +   N      R  + +   + D L     P   LKD G +  +  ++ IT+ 
Sbjct: 206 DMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASVCSP-SQLKDDGSIGRDPSMSAITSL 264

Query: 291 ---ECLKEEGKTSALTCSLPKN----EDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQ 343
                +  +G          +N    EDL    S+ R +      FS   +  ++K+   
Sbjct: 265 TVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSPRTDLGSPNSFSHMSEGILMKKEPA 324

Query: 344 EDSKSLDLKDNDVIQDSSSALHVSSK-DVPSSLSCLPASGSMCGSLIESKARGDFLPQHE 402
           E+S + +           S L +  K D+P+              L+ ++ R D    +E
Sbjct: 325 EESTTEE--------SLRSGLPLLLKPDMPNGSGRNNDCERCSDCLVPNEVRADENEGYE 376

Query: 403 HKDNIQDAVTIHEEIQNSVVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQT- 461
           H++ +        E  N      E F E+  +   K   +        M D +++ ++  
Sbjct: 377 HEETLGTT-----EFLNMT----EHFSESQDMTNWKLTKL------NEMNDSQVNEEKEK 421

Query: 462 ---VIRAESLDGGDTSSTVVESQEGLS--GTHVPESSDC-CEGFINTFSSNDMDGQDLDY 515
              + + E  +G      V  +  GL   GT + ES +C     I+T ++N +      Y
Sbjct: 422 FLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDSY 481

Query: 516 FNIDEGAKSGPLISDAELDAFLTEQYLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNIN 575
              D G    P    ++ D+ +TE           E+ + +SKS+              +
Sbjct: 482 GMQDPGVSFVPKTLPSKEDS-VTE-----------EKEIEESKSEC------------YS 517

Query: 576 NIYFNAEAGAIGESHGINIICETVD--KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQ 633
           NIY         E  G+ ++  T D  K+N + N  S      +P   G  + K      
Sbjct: 518 NIY-EQRGNEATEGSGL-LLNSTGDLMKKNYLHNFCS-----QVPSVLGQSSPKV----- 565

Query: 634 LSVSDINSQSV--GGARPKQLFSLPSRT-RSSKDLNKPDVPDTIESEPSTADTVVPITCA 690
             V+ + S SV  GGARPKQ  +L  +  +   D  + D P    +     + ++     
Sbjct: 566 --VASLPSISVPFGGARPKQPSNLKLQIPKPLSDHLQNDFPANSGNNTKNKNDILGKAKL 623

Query: 691 IDSTADPQVSFN-SNYIDIESNSEGGSSFVT--------ANEDSVPENTCKEG------- 734
            +++A    S +  N  ++++N E   S+          A     P+N  + G       
Sbjct: 624 GENSATNVCSPSLGNISNVDTNGEHLESYEAEISTRPCLALAPDSPDNDLRAGQFGISAR 683

Query: 735 ---LVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLE 791
                LG+  P WVPDS+APNCM C+ +FTFTKRRHHCRACGKVFC  CC+ KCKL Y++
Sbjct: 684 KPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMD 743

Query: 792 -KEARVCVVCYETI 804
            KEARVCV+C+  +
Sbjct: 744 RKEARVCVICHSVL 757


>gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens]
          Length = 1430

 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 54/154 (35%), Positives = 74/154 (48%), Gaps = 8/154 (5%)

Query: 724  DSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNR 783
            D       +E   LG K P W+PD+ A  CM C  +FT T RRHHCRACGK+ C  C + 
Sbjct: 1199 DEADSENKEEVSPLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSN 1258

Query: 784  KCKLQYLEKE-ARVCVVCYETISKA--QAFERMMSPTGSNLKSNHSDECTTVQP-PQENQ 839
            K  L YL+ + ARVC  C++ + K   Q   R+ SP   N KS  S   + +   P   +
Sbjct: 1259 KYGLDYLKNQPARVCEHCFQELQKLDHQHSPRIGSP--GNHKSPSSALSSVLHSIPSGRK 1316

Query: 840  TSSIPSPATLPVSALKQPGVEGLC--SKEQKRVW 871
               IP+      +  +   + G    SK  K+ W
Sbjct: 1317 QKKIPAALKEVSANTEDSSMSGYLYRSKGNKKPW 1350


>gi|217272865 myotubularin related protein 4 [Homo sapiens]
          Length = 1195

 Score = 74.7 bits (182), Expect = 6e-13
 Identities = 42/123 (34%), Positives = 61/123 (49%), Gaps = 4/123 (3%)

Query: 695  ADPQVSFNSNYIDI-ESNSEGGSSFVTANEDSVPENTCKEGLVLGQKQPT-WVPDSEAPN 752
            A+P + +  ++  + ES+      F + + +        E +   + + T WVPD  A +
Sbjct: 1060 AEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCLSEASWEPVDKKETEVTRWVPDHMASH 1119

Query: 753  CMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKL--QYLEKEARVCVVCYETISKAQAF 810
            C NC  +F   KRRHHCR CG VFC  CC+ K  +  Q L     VC  CYE I  ++A 
Sbjct: 1120 CYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRAR 1179

Query: 811  ERM 813
            E M
Sbjct: 1180 ELM 1182


>gi|194018497 FYVE, RhoGEF and PH domain containing 5 [Homo sapiens]
          Length = 1462

 Score = 74.7 bits (182), Expect = 6e-13
 Identities = 50/154 (32%), Positives = 72/154 (46%), Gaps = 18/154 (11%)

Query: 734  GLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYL-EK 792
            G+ LG++ PT VP +    CMNC   F+ T RRHHC ACGK+ C  C   K  L+YL ++
Sbjct: 1229 GVSLGERPPTLVPVTHVMMCMNCGCDFSLTLRRHHCHACGKIVCRNCSRNKYPLKYLKDR 1288

Query: 793  EARVCVVCYETISK-AQAFERMM------------SPTGSNLKSNHSDECTTVQPPQENQ 839
             A+VC  C+  + K  +A   +M            SP  S   S  S    ++ P    +
Sbjct: 1289 MAKVCDGCFGELKKRGRAVPGLMRERPVSMSFPLSSPRFSG--SAFSSVFQSINPSTFKK 1346

Query: 840  TSSIPSPATLPVSALKQPGVEGLCS--KEQKRVW 871
               +PS  T   ++ +   + G  S  K  KR W
Sbjct: 1347 QKKVPSALTEVAASGEGSAISGYLSRCKRGKRHW 1380


>gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens]
          Length = 234

 Score = 74.7 bits (182), Expect = 6e-13
 Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 4/92 (4%)

Query: 726 VPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKC 785
           VPE+    G   G ++P WVPD E   CM C  KF F  R+HHCR CGK FC  CC++K 
Sbjct: 24  VPEHRAF-GSPFGLEEPQWVPDKECRRCMQCDAKFDFLTRKHHCRRCGKCFCDRCCSQKV 82

Query: 786 KLQYL--EKEARVCVVC-YETISKAQAFERMM 814
            L+ +      R C  C   ++ +A+ +++ +
Sbjct: 83  PLRRMCFVDPVRQCAECALVSLKEAEFYDKQL 114


>gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
           substrate [Homo sapiens]
          Length = 777

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 42/126 (33%), Positives = 60/126 (47%), Gaps = 21/126 (16%)

Query: 727 PENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCK 786
           PE    + +   ++ P WV   +A  C  C+V+F    R+HHCRACG++FCG C ++   
Sbjct: 143 PEFKESDAMFAAERAPDWV---DAEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYST 199

Query: 787 LQY--LEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQTSSIP 844
           +    +EKE RVC  CYE +               N K+      TT  PP E  TS + 
Sbjct: 200 IPKFGIEKEVRVCEPCYEQL---------------NRKAEGKATSTTELPP-EYLTSPLS 243

Query: 845 SPATLP 850
             + LP
Sbjct: 244 QQSQLP 249


>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
           isoform 2 [Homo sapiens]
          Length = 2098

 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 35/100 (35%), Positives = 52/100 (52%), Gaps = 4/100 (4%)

Query: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKC--KLQYLEKEARVCVVCY 801
           W+PDS+   C +C  KFT  +RRHHCR CG++FC  CCN++   K      + R C  C 
Sbjct: 155 WMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYC- 213

Query: 802 ETISKAQAFERMMSPTGSNLKSNHSDECT-TVQPPQENQT 840
             I+ + A     +  G +L +     C+ +V  P E +T
Sbjct: 214 RKIALSYAHSTDSNSIGEDLNALSDSACSVSVLDPSEPRT 253


>gi|198041928 FYVE, RhoGEF and PH domain containing 4 [Homo sapiens]
          Length = 766

 Score = 70.9 bits (172), Expect = 9e-12
 Identities = 33/71 (46%), Positives = 45/71 (63%), Gaps = 2/71 (2%)

Query: 737 LGQKQPTWVPDSEAPNCMNCQVKFT-FTKRRHHCRACGKVFCGVCCNRKCKLQY-LEKEA 794
           LG++ P W+ D+E   CM C+  F   T+RRHHCRACG V C  C + K +L+Y   K +
Sbjct: 549 LGKRAPRWIRDNEVTMCMKCKEPFNALTRRRHHCRACGYVVCWKCSDYKAQLEYDGGKLS 608

Query: 795 RVCVVCYETIS 805
           +VC  CY+ IS
Sbjct: 609 KVCKDCYQIIS 619


>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens]
          Length = 1478

 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 29/91 (31%), Positives = 51/91 (56%), Gaps = 5/91 (5%)

Query: 744  WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEARVCVVCYET 803
            W+ D+EA +C++C+ +F++  RRHHCR CG++FC  CCN     ++  K+ R C  C++ 
Sbjct: 1170 WLGDTEANHCLDCKREFSWMVRRHHCRICGRIFCYYCCNNYVLSKHGGKKERCCRACFQK 1229

Query: 804  ISKAQAFERMMSPTGSNLKSNHSDECTTVQP 834
            +S+        SP  S   ++  +    + P
Sbjct: 1230 LSEGPG-----SPDSSGSGTSQGEPSPALSP 1255


>gi|13375827 phafin 2 [Homo sapiens]
          Length = 249

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 33/64 (51%), Positives = 38/64 (59%), Gaps = 2/64 (3%)

Query: 744 WVPDSEAPNCMNCQ-VKFTFTKRRHHCRACGKVFCGVCCNRKCKL-QYLEKEARVCVVCY 801
           WVPDSEA  CM CQ  KFT   RRHHCR CG V CG C  ++  L     K  R+C  CY
Sbjct: 149 WVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCY 208

Query: 802 ETIS 805
           + +S
Sbjct: 209 DLLS 212


>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
          Length = 1161

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 28/63 (44%), Positives = 37/63 (58%), Gaps = 2/63 (3%)

Query: 744  WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKL--QYLEKEARVCVVCY 801
            W+PD  A +C  C   F    R+HHCR CG VFC  CCN+K  +  Q L + +RVC  CY
Sbjct: 1079 WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCY 1138

Query: 802  ETI 804
             ++
Sbjct: 1139 SSL 1141


>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
          Length = 1198

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 28/63 (44%), Positives = 37/63 (58%), Gaps = 2/63 (3%)

Query: 744  WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKL--QYLEKEARVCVVCY 801
            W+PD  A +C  C   F    R+HHCR CG VFC  CCN+K  +  Q L + +RVC  CY
Sbjct: 1116 WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCY 1175

Query: 802  ETI 804
             ++
Sbjct: 1176 SSL 1178


>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
           sapiens]
          Length = 641

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 30/79 (37%), Positives = 43/79 (54%), Gaps = 7/79 (8%)

Query: 723 EDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCN 782
           ED    N   +GLV       W+ D EA +C  C+ +F+ +KR+HHCR CG++FC  C +
Sbjct: 558 EDIKEANKALQGLV-------WLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSD 610

Query: 783 RKCKLQYLEKEARVCVVCY 801
            +  L    K  RVC  C+
Sbjct: 611 NELPLPSSPKPVRVCDSCH 629


>gi|24797153 faciogenital dysplasia protein [Homo sapiens]
          Length = 961

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 34/82 (41%), Positives = 47/82 (57%), Gaps = 5/82 (6%)

Query: 722 NEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKF-TFTKRRHHCRACGKVFCGVC 780
           +ED+ P +     + LG++ PT + + E   CM CQ  F + TKRRHHC+ACG V CG C
Sbjct: 708 DEDTPPNSP---NVDLGKRAPTPIREKEVTMCMRCQEPFNSITKRRHHCKACGHVVCGKC 764

Query: 781 CNRKCKLQY-LEKEARVCVVCY 801
              + +L Y   +  RVC  CY
Sbjct: 765 SEFRARLVYDNNRSNRVCTDCY 786


>gi|189217917 FYVE, RhoGEF and PH domain containing 2 [Homo sapiens]
          Length = 655

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 37/104 (35%), Positives = 52/104 (50%), Gaps = 3/104 (2%)

Query: 700 SFNSNYIDIESNSEGGSSFVTANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVK 759
           +F +    IE  +E   +     E  + E   +    LG + P WV D     CM CQ  
Sbjct: 412 AFQAAIDQIEKRNETFKAAAQGPEGDIQEQELQSE-ELGLRAPQWVRDKMVTMCMRCQEP 470

Query: 760 FT-FTKRRHHCRACGKVFCGVCCNRKCKLQYLE-KEARVCVVCY 801
           F   T+RRHHCRACG V C  C + + +L+Y + +  RVC+ CY
Sbjct: 471 FNALTRRRHHCRACGYVVCARCSDYRAELKYDDNRPNRVCLHCY 514


>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
           sapiens]
          Length = 600

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 24/62 (38%), Positives = 36/62 (58%)

Query: 740 KQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEARVCVV 799
           K   W+ D EA +C  C+ +F+ ++R+HHCR CG +FC  C + +  L    K  RVC  
Sbjct: 527 KGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDS 586

Query: 800 CY 801
           C+
Sbjct: 587 CH 588


>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
           sapiens]
          Length = 600

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 24/62 (38%), Positives = 36/62 (58%)

Query: 740 KQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEARVCVV 799
           K   W+ D EA +C  C+ +F+ ++R+HHCR CG +FC  C + +  L    K  RVC  
Sbjct: 527 KGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDS 586

Query: 800 CY 801
           C+
Sbjct: 587 CH 588


>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
           sapiens]
          Length = 708

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 24/62 (38%), Positives = 36/62 (58%)

Query: 740 KQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEARVCVV 799
           K   W+ D EA +C  C+ +F+ ++R+HHCR CG +FC  C + +  L    K  RVC  
Sbjct: 635 KGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDS 694

Query: 800 CY 801
           C+
Sbjct: 695 CH 696


>gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens]
          Length = 887

 Score = 64.7 bits (156), Expect = 7e-10
 Identities = 28/62 (45%), Positives = 36/62 (58%), Gaps = 2/62 (3%)

Query: 742 PTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKL-QYLE-KEARVCVV 799
           P WVPD     C  C+  FT  +R+HHCR+CGK+FC  C +    L +Y + K  RVC  
Sbjct: 812 PEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTH 871

Query: 800 CY 801
           CY
Sbjct: 872 CY 873


>gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens]
          Length = 2539

 Score = 64.7 bits (156), Expect = 7e-10
 Identities = 45/154 (29%), Positives = 64/154 (41%), Gaps = 8/154 (5%)

Query: 681  ADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFV---TANEDSVPENTCKEGLVL 737
            +D+V+ +   +   ADP+    S   +    +  G S +   +  E S P     +  V 
Sbjct: 1740 SDSVIHLQEIVHQAADPETLPRSPSAEFSPAAPPGISSIHSPSLRERSFPPTQPSQEFVP 1799

Query: 738  GQKQPT---WVPDSEAPNCMNC-QVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQ-YLEK 792
                P    WVPD     CM C +  FT   RRHHCR CG++ C  C  +K  ++   E 
Sbjct: 1800 PATPPARHQWVPDETESICMVCCREHFTMFNRRHHCRRCGRLVCSSCSTKKMVVEGCREN 1859

Query: 793  EARVCVVCYETISKAQAFERMMSPTGSNLKSNHS 826
             ARVC  CY   +K    E    P   +   N S
Sbjct: 1860 PARVCDQCYSYCNKDVPEEPSEKPEALDSSKNES 1893


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 25/61 (40%), Positives = 32/61 (52%)

Query: 744  WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEARVCVVCYET 803
            W  D+E  NCM C   F+ T RRHHCR CG +FC  C  +       +K  RVC  C+  
Sbjct: 1349 WAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAECSAKNALTPSSKKPVRVCDACFND 1408

Query: 804  I 804
            +
Sbjct: 1409 L 1409


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 128/718 (17%), Positives = 257/718 (35%), Gaps = 53/718 (7%)

Query: 10   SDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQECVNSCASS 69
            SD D   D  + N  +     D  ++ +S++ S SS+ + S  +S         +S  SS
Sbjct: 634  SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSS 693

Query: 70   ETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMGRCSKPICDL 129
            ++S  +  S  ++ +    +   +  N    D  SS    +SD          S    D 
Sbjct: 694  DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD----------SSNSSDS 743

Query: 130  ISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDHDSDTVREQQ 189
             SD  +  ++++S +        D   ++DS    D S+ SD+   S++   SD+     
Sbjct: 744  -SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSD 802

Query: 190  NDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIVDFNMSSALT 249
            +  SS+  +             D++ SDS N S + N  D             + +S+ +
Sbjct: 803  SSNSSDSSDSS-----------DSSDSDSSNSSDSSNSSDSSD----------SSNSSDS 841

Query: 250  RQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTSALTCSLPKN 309
              SS      D             D     +  + +  + +    E   +S  + S   +
Sbjct: 842  SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS 901

Query: 310  EDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDSSSALHVSSK 369
            +    + SNS D +    D S   D +    S+   + S     +D    S S+    S 
Sbjct: 902  DSDSSDSSNSSDSS----DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957

Query: 370  DVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNSVVLGGEPFK 429
            +   S +   +S S      +S    D     +  D+   + + +    +      +   
Sbjct: 958  NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSN 1017

Query: 430  ENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVESQEGLSGTHV 489
             +D        +    S      D   D   +   ++S +  D+S +  +S +    +  
Sbjct: 1018 SSDSSNSSDSSNSSDSSDSSDSSDSS-DSSDSSDSSDSSNSSDSSDSS-DSSDSSDSSDS 1075

Query: 490  PESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQYLQTTNIKS 549
             +SSD  E   ++ SSN  D  D    + D    S    S    D+  +     +++   
Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSD----SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1131

Query: 550  FEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVDKQNTIENGL 609
              ++ + S S  +    +  D  + ++   ++++    +S   +    + D  ++ ++  
Sbjct: 1132 SSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1191

Query: 610  SLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTRSSKDLNKPD 669
            S     +        +S S  ++  S S  +S S   +   +       + SS   N  D
Sbjct: 1192 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSD 1251

Query: 670  VPDTIESEPSTADTVVPITCAIDSTADPQVSF---NSNYIDIESNSEGGSSFVTANED 724
              D+ +S  ST+D+        +  +D Q      N+N  D +S+SEG  S  + ++D
Sbjct: 1252 SSDSSDSSDSTSDS--------NDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 127/729 (17%), Positives = 252/729 (34%), Gaps = 29/729 (3%)

Query: 6    KAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQECVNS 65
            K+  SD D    D   + D  D      ++ DSN  S S    S    S      +  NS
Sbjct: 546  KSDSSDSDS--SDSSNSSDSSD--SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNS 601

Query: 66   CASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLS-SVDGGTSDEIQPLYMGRCSK 124
              SS++S  ++ S  ++ +     S ++E + +  D  S S D  +SD            
Sbjct: 602  SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDN-------- 653

Query: 125  PICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDHDSDT 184
                  SD  +  +++NS +        D  S++DS    D S  SD+   S +   SD+
Sbjct: 654  ------SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDS 707

Query: 185  VREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIVDFNM 244
                 +D SS+  N       +      +  SDS N S + +  D    +      D + 
Sbjct: 708  SDSDSSD-SSDSSN---SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763

Query: 245  SSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTSALTC 304
            SS  +  S     +       S       D        D +  + +    +   + +   
Sbjct: 764  SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823

Query: 305  SLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDSSSAL 364
            S   N     + SNS D +         +  +  +  +   S S D  D+    DSS + 
Sbjct: 824  SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS- 882

Query: 365  HVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNSVVLG 424
               S +  +S     +S S      +S    D        D+ + + +      +     
Sbjct: 883  -SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNS 941

Query: 425  GEPFKENDLL-KQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVESQEG 483
             +    +D     +   S    +  +  +    D   +   ++S D  D+S +  +S + 
Sbjct: 942  SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDS-SDSSDS 1000

Query: 484  LSGTHVPESSDCCEGFINTFSSNDMDGQDL--DYFNIDEGAKSGPLISDAELDAFLTEQY 541
             + +   +SSD  +   ++ SSN  D  +      + D    S    S    D+  +   
Sbjct: 1001 SNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1060

Query: 542  LQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVDK 601
              +++     ++ + S S  +       D  N ++   ++++    +S   +   ++ D 
Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1120

Query: 602  QNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTRS 661
             N+ ++  S     +        +S S  ++  S S  +S S   +           + S
Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1180

Query: 662  SKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVTA 721
            S   +  D  D+ +S  S+  +    +     ++D   S +S+     S+S   S    +
Sbjct: 1181 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDS 1240

Query: 722  NEDSVPENT 730
            ++ S   N+
Sbjct: 1241 SDSSDSSNS 1249



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 79/423 (18%), Positives = 155/423 (36%), Gaps = 19/423 (4%)

Query: 309 NEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDSSSALHVSS 368
           N D   N +N  D+N K      + D      S  + S S +  D+    DS S+   SS
Sbjct: 523 NSDSNGNGNNGNDDNDKSDSGKGKSD-----SSDSDSSDSSNSSDSSDSSDSDSSDSNSS 577

Query: 369 KDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNSVVLGGEPF 428
            D  SS S   +S S      +S    D     +  D+   + +   +  +S        
Sbjct: 578 SDSDSSDS--DSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSS-------- 627

Query: 429 KENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVESQEGLSGTH 488
           K          KS    S      D   D   +   + S D  D+S +  +S      ++
Sbjct: 628 KSESDSSDSDSKSDSSDSNSSDSSDNS-DSSDSSNSSNSSDSSDSSDS-SDSSSSSDSSN 685

Query: 489 VPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQYLQTTNIK 548
             +SSD  +   ++ SS+  D  D D  +  + + S    SD+   +  ++    +++  
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS-SNSSDSS 744

Query: 549 SFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVDKQNTIENG 608
              ++ N S S  +       D  + ++   ++++    +S+  +   ++ D  N+ ++ 
Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804

Query: 609 LSLGEKSTIPVQQGLPTSKSEITNQLSVSD-INSQSVGGARPKQLFSLPSRTRSSKDLNK 667
            S     +        ++ S+ +N    SD  NS     +      S    +  S   N 
Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864

Query: 668 PDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVTANEDSVP 727
            D  D+ +S  S+  +    +    +++D   S NS+  D   +S    S  ++N     
Sbjct: 865 SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS 924

Query: 728 ENT 730
           E++
Sbjct: 925 ESS 927


>gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Homo
           sapiens]
          Length = 281

 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 2/70 (2%)

Query: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLE--KEARVCVVCY 801
           WV D    +C  C V+F+ T+RRHHCR CG++FC  C   + +++ L+     RVC  CY
Sbjct: 206 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265

Query: 802 ETISKAQAFE 811
             +   +  E
Sbjct: 266 YNLQHERGSE 275


>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
            sapiens]
          Length = 3526

 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 2/70 (2%)

Query: 744  WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLE--KEARVCVVCY 801
            WV D    +C  C V+F+ T+RRHHCR CG++FC  C   + +++ L+     RVC  CY
Sbjct: 3451 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 3510

Query: 802  ETISKAQAFE 811
              +   +  E
Sbjct: 3511 YNLQHERGSE 3520


>gi|153791377 apoptosis-inducing protein D [Homo sapiens]
          Length = 279

 Score = 61.2 bits (147), Expect = 7e-09
 Identities = 29/70 (41%), Positives = 37/70 (52%), Gaps = 2/70 (2%)

Query: 744 WVPDSEAPNCMNC-QVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLE-KEARVCVVCY 801
           W+PD     CM C Q +F+   RRHHCR CG V C  C  ++  L  L  K  RVC +CY
Sbjct: 149 WIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCY 208

Query: 802 ETISKAQAFE 811
             ++  Q  E
Sbjct: 209 RELAAQQRQE 218


>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
          Length = 1170

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 28/72 (38%), Positives = 37/72 (51%), Gaps = 11/72 (15%)

Query: 744  WVPDSEAPNCMNCQVKFTFTKRRHHCR---------ACGKVFCGVCCNRKCKL--QYLEK 792
            W+PD  A +C  C   F    R+HHCR          CG VFC  CCN+K  +  Q L +
Sbjct: 1079 WLPDHLAAHCYACDSAFWLASRKHHCRDTDRVDQTWNCGNVFCSSCCNQKVPVPSQQLFE 1138

Query: 793  EARVCVVCYETI 804
             +RVC  CY ++
Sbjct: 1139 PSRVCKSCYSSL 1150


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.131    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,981,085
Number of Sequences: 37866
Number of extensions: 2717830
Number of successful extensions: 7761
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 7514
Number of HSP's gapped (non-prelim): 184
length of query: 1539
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1424
effective length of database: 13,892,928
effective search space: 19783529472
effective search space used: 19783529472
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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