Guide to the Human Genome
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Search of human proteins with 157419140

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157419140 laminin, gamma 2 isoform b precursor [Homo
sapiens]
         (1111 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]     2307   0.0  
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]     2303   0.0  
gi|145309326 laminin, gamma 1 precursor [Homo sapiens]                805   0.0  
gi|110611156 laminin, gamma 3 precursor [Homo sapiens]                565   e-161
gi|38788416 laminin, alpha 1 precursor [Homo sapiens]                 358   2e-98
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s...   313   6e-85
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa...   313   6e-85
gi|21264602 laminin alpha 5 [Homo sapiens]                            301   2e-81
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]         245   2e-64
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]          235   2e-61
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]            225   2e-58
gi|167614504 laminin, beta 1 precursor [Homo sapiens]                 167   4e-41
gi|119703755 laminin, beta 2 precursor [Homo sapiens]                 159   1e-38
gi|143770880 laminin, beta 4 [Homo sapiens]                           158   3e-38
gi|62868217 laminin, beta 3 precursor [Homo sapiens]                  135   2e-31
gi|62868215 laminin, beta 3 precursor [Homo sapiens]                  135   2e-31
gi|189083719 laminin, beta 3 precursor [Homo sapiens]                 135   2e-31
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]      132   2e-30
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]      129   1e-29
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]      129   1e-29
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]         124   5e-28
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]               120   5e-27
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]          114   4e-25
gi|219842266 usherin isoform B [Homo sapiens]                         105   2e-22
gi|219842259 usherin isoform A [Homo sapiens]                         105   2e-22
gi|5453810 netrin 3 [Homo sapiens]                                    105   3e-22
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]              103   1e-21
gi|93204871 netrin 4 [Homo sapiens]                                   102   2e-21
gi|190014607 netrin G2 [Homo sapiens]                                  97   6e-20
gi|164414431 netrin G1 isoform 1 [Homo sapiens]                        96   2e-19

>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
          Length = 1111

 Score = 2307 bits (5979), Expect = 0.0
 Identities = 1111/1111 (100%), Positives = 1111/1111 (100%)

Query: 1    MPALWLGCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNT 60
            MPALWLGCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNT
Sbjct: 1    MPALWLGCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNT 60

Query: 61   DGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGF 120
            DGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGF
Sbjct: 61   DGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGF 120

Query: 121  HMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGN 180
            HMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGN
Sbjct: 121  HMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGN 180

Query: 181  PEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVF 240
            PEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVF
Sbjct: 181  PEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVF 240

Query: 241  SSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPL 300
            SSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPL
Sbjct: 241  SSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPL 300

Query: 301  MPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYI 360
            MPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYI
Sbjct: 301  MPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYI 360

Query: 361  DNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG 420
            DNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG
Sbjct: 361  DNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG 420

Query: 421  GGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV 480
            GGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV
Sbjct: 421  GGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV 480

Query: 481  CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK 540
            CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK
Sbjct: 481  CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK 540

Query: 541  CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGP 600
            CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGP
Sbjct: 541  CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGP 600

Query: 601  NCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQAL 660
            NCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQAL
Sbjct: 601  NCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQAL 660

Query: 661  QDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTH 720
            QDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTH
Sbjct: 661  QDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTH 720

Query: 721  RLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTR 780
            RLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTR
Sbjct: 721  RLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTR 780

Query: 781  ETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIE 840
            ETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIE
Sbjct: 781  ETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIE 840

Query: 841  ADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLG 900
            ADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLG
Sbjct: 841  ADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLG 900

Query: 901  NWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDL 960
            NWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDL
Sbjct: 901  NWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDL 960

Query: 961  QVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE 1020
            QVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE
Sbjct: 961  QVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE 1020

Query: 1021 IEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITE 1080
            IEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITE
Sbjct: 1021 IEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITE 1080

Query: 1081 AQKVDTRAKNAGVTIQDTLNTLDGLLHLMGM 1111
            AQKVDTRAKNAGVTIQDTLNTLDGLLHLMGM
Sbjct: 1081 AQKVDTRAKNAGVTIQDTLNTLDGLLHLMGM 1111


>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
          Length = 1193

 Score = 2303 bits (5968), Expect = 0.0
 Identities = 1109/1109 (100%), Positives = 1109/1109 (100%)

Query: 1    MPALWLGCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNT 60
            MPALWLGCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNT
Sbjct: 1    MPALWLGCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNT 60

Query: 61   DGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGF 120
            DGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGF
Sbjct: 61   DGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGF 120

Query: 121  HMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGN 180
            HMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGN
Sbjct: 121  HMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGN 180

Query: 181  PEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVF 240
            PEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVF
Sbjct: 181  PEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVF 240

Query: 241  SSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPL 300
            SSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPL
Sbjct: 241  SSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPL 300

Query: 301  MPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYI 360
            MPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYI
Sbjct: 301  MPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYI 360

Query: 361  DNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG 420
            DNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG
Sbjct: 361  DNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG 420

Query: 421  GGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV 480
            GGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV
Sbjct: 421  GGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV 480

Query: 481  CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK 540
            CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK
Sbjct: 481  CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK 540

Query: 541  CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGP 600
            CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGP
Sbjct: 541  CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGP 600

Query: 601  NCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQAL 660
            NCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQAL
Sbjct: 601  NCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQAL 660

Query: 661  QDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTH 720
            QDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTH
Sbjct: 661  QDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTH 720

Query: 721  RLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTR 780
            RLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTR
Sbjct: 721  RLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTR 780

Query: 781  ETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIE 840
            ETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIE
Sbjct: 781  ETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIE 840

Query: 841  ADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLG 900
            ADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLG
Sbjct: 841  ADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLG 900

Query: 901  NWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDL 960
            NWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDL
Sbjct: 901  NWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDL 960

Query: 961  QVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE 1020
            QVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE
Sbjct: 961  QVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE 1020

Query: 1021 IEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITE 1080
            IEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITE
Sbjct: 1021 IEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITE 1080

Query: 1081 AQKVDTRAKNAGVTIQDTLNTLDGLLHLM 1109
            AQKVDTRAKNAGVTIQDTLNTLDGLLHLM
Sbjct: 1081 AQKVDTRAKNAGVTIQDTLNTLDGLLHLM 1109


>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
          Length = 1609

 Score =  805 bits (2080), Expect = 0.0
 Identities = 441/1230 (35%), Positives = 669/1230 (54%), Gaps = 151/1230 (12%)

Query: 9    CLCFSLLLPAARATSRREV----CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIH 64
            CL F    P  RAT+        CDCNG+S++C FD EL+R TG+G  C NC DNTDG H
Sbjct: 319  CLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAH 378

Query: 65   CEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLT 124
            CE+C+  F+R    + C  C+C+  GSLS +CD+ GRCSCKPGV G +CDRC PGFH LT
Sbjct: 379  CERCRENFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLT 438

Query: 125  DAGCTQDQRLLDSKCDCDPAGIAGPC--DAGRCVCKPAVTGERCDRCRSGYYNLDGGNPE 182
            +AGC          C CDP+G    C  + GRCVCK  V G  C+RC+ G++NL+  NP 
Sbjct: 439  EAGCRP--------CSCDPSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPR 490

Query: 183  GCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVFSS 242
            GCT CFC+GHS+ C ++  YSV+ I+STF  D DGW+A QR+GS A L+WS   QD+   
Sbjct: 491  GCTPCFCFGHSSVCTNAVGYSVYSISSTFQIDEDGWRAEQRDGSEASLEWSSERQDIAVI 550

Query: 243  AQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPLMP 302
            +    P YF+APAKFLG Q +SYGQ+LSF +RVDR     SA D++LEGAGLR++ PL+ 
Sbjct: 551  SDSYFPRYFIAPAKFLGKQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVSVPLIA 610

Query: 303  LGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYIDN 362
             G + P   T  Y FRL+E     W P L+ FE+++LL NLT+++IR TY E S GY+D+
Sbjct: 611  QGNSYPSETTVKYVFRLHEATDYPWRPALTPFEFQKLLNNLTSIKIRGTYSERSAGYLDD 670

Query: 363  VTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG 422
            VTL SARP  G PA WVE C CPVGY GQFC+ C SGY+R++  LGP+  C+ C C G  
Sbjct: 671  VTLASARPGPGVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHS 730

Query: 423  -ACDPDTGDC-----------------YSGD------------------------ENPDI 440
              CDP+TG C                 Y GD                        +  ++
Sbjct: 731  ETCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEV 790

Query: 441  ECADCPIG------------FYNDP---HDP-RSCKPCPCHNGFSCSVMPETEEVV--CN 482
             C +CP G            ++ DP   + P R C+ C C +    + +     +   C 
Sbjct: 791  VCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECL 850

Query: 483  NCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCN---------------------- 520
             C     G  C+ C DG+FG+P   + P   C+ C CN                      
Sbjct: 851  KCIYNTAGFYCDRCKDGFFGNPLAPN-PADKCKACNCNLYGTMKQQSSCNPVTGQCECLP 909

Query: 521  -------NNVDP--------------------SASGNCDRLTGRCLKCIHNTAGIYCDQC 553
                      DP                    S +G CD  TG+C +C     G +C++C
Sbjct: 910  HVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQC-ECQPGITGQHCERC 968

Query: 554  KAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEH--------- 604
            +  +FG    P   + C+ C+C+P GS  + C+ DG C C+ GF G  C+          
Sbjct: 969  EVNHFG--FGP---EGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNR 1023

Query: 605  ---GAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQ 661
               G   CPACY  VK ++     +LQ +E+LI+    GD +V D   E R+++AE+ + 
Sbjct: 1024 SWPGCQECPACYRLVKDKVADHRVKLQELESLIANLGTGDEMVTDQAFEDRLKEAEREVM 1083

Query: 662  DILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHR 721
            D+LR+AQ  +   ++L  +L +V +  +S  SRL +++ T+E    L  Q +  V +T R
Sbjct: 1084 DLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVENTER 1143

Query: 722  LITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRE 781
            LI      L +++ +  N ++   +    PN    LA+EA +LAE H + A ++ ++ + 
Sbjct: 1144 LIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKT 1203

Query: 782  TEDYSKQALSLVRKALHEGVGSGSGSPDGAV-VQGLVEKLEKTKSLAQQLTREATQAEIE 840
              D S +A +L+ + L       +G    A  ++ L  K E+ K+++Q L ++A +   E
Sbjct: 1204 ANDTSTEAYNLLLRTL-------AGENQTAFEIEELNRKYEQAKNISQDLEKQAARVHEE 1256

Query: 841  ADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLG 900
            A R+   ++ +  SV++L  +  ++ +  EA  IK +A++L  L+ + + +++  ++++ 
Sbjct: 1257 AKRAGDKAVEIYASVAQLSPLDSETLE-NEANNIKMEAENLEQLIDQKLKDYEDLREDMR 1315

Query: 901  NWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDL 960
              + E + LL+ GK+ ++ +DQLL+RA+ AK+ A+EA   G  T  E   IL NL++FD 
Sbjct: 1316 GKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDR 1375

Query: 961  QVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE 1020
            +V++ K  AEEA++++  I+Q +++A++KT++A++ALGSAAADA  AKN A EA  I+S 
Sbjct: 1376 RVNDNKTAAEEALRKIPAINQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASA 1435

Query: 1021 IEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITE 1080
            +++   S   EA  T      ++  + ++  +++E E EL+RK+ + D +M    M    
Sbjct: 1436 VQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQA 1495

Query: 1081 AQKVDTRAKNAGVTIQDTLNTLDGLLHLMG 1110
            AQ+ +  A+ A  ++   L+ ++ LL  +G
Sbjct: 1496 AQEAEINARKAKNSVTSLLSIINDLLEQLG 1525



 Score =  628 bits (1620), Expect = e-180
 Identities = 312/662 (47%), Positives = 391/662 (59%), Gaps = 97/662 (14%)

Query: 28  CDCNGKSRQCI---FDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR-------- 76
           C CNG + +C+   FD+ +           NC  NT G+ CEKC   F+  R        
Sbjct: 286 CKCNGHASECMKNEFDKLV----------CNCKHNTYGVDCEKCL-PFFNDRPWRRATAE 334

Query: 77  ERDRCLPCNCNSK----------------------------GSLSARC------------ 96
               CLPC+CN +                            G+   RC            
Sbjct: 335 SASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEA 394

Query: 97  ----------------DNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCD 140
                           D+ GRCSCKPGV G +CDRC PGFH LT+AGC          C 
Sbjct: 395 CSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGC--------RPCS 446

Query: 141 CDPAGIAGPC--DAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRS 198
           CDP+G    C  + GRCVCK  V G  C+RC+ G++NL+  NP GCT CFC+GHS+ C +
Sbjct: 447 CDPSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTN 506

Query: 199 SAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFL 258
           +  YSV+ I+STF  D DGW+A QR+GS A L+WS   QD+   +    P YF+APAKFL
Sbjct: 507 AVGYSVYSISSTFQIDEDGWRAEQRDGSEASLEWSSERQDIAVISDSYFPRYFIAPAKFL 566

Query: 259 GNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFR 318
           G Q +SYGQ+LSF +RVDR     SA D++LEGAGLR++ PL+  G + P   T  Y FR
Sbjct: 567 GKQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVSVPLIAQGNSYPSETTVKYVFR 626

Query: 319 LNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYIDNVTLISARPVSGAPAPW 378
           L+E     W P L+ FE+++LL NLT+++IR TY E S GY+D+VTL SARP  G PA W
Sbjct: 627 LHEATDYPWRPALTPFEFQKLLNNLTSIKIRGTYSERSAGYLDDVTLASARPGPGVPATW 686

Query: 379 VEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDEN 437
           VE C CPVGY GQFC+ C SGY+R++  LGP+  C+ C C G    CDP+TG C   D  
Sbjct: 687 VESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVCNCRDNT 746

Query: 438 PDIECADCPIGFYNDPHDPRS--CKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCEL 495
               C  C  G+Y D     S  C+PCPC  G SC+V+P+T+EVVC NCP G TG RCEL
Sbjct: 747 AGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCEL 806

Query: 496 CADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKA 555
           C DGYFGDP G +GPVR C+ CQC++N+DP+A GNC+RLTG CLKCI+NTAG YCD+CK 
Sbjct: 807 CDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKD 866

Query: 556 GYFGDPLAPNPADKCRACNCNPMGS--EPVGCRS-DGTCVCKPGFGGPNCEHGAFSCPAC 612
           G+FG+PLAPNPADKC+ACNCN  G+  +   C    G C C P   G +C  GA   P  
Sbjct: 867 GFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDC--GACD-PGF 923

Query: 613 YN 614
           YN
Sbjct: 924 YN 925



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 82/432 (18%), Positives = 175/432 (40%), Gaps = 44/432 (10%)

Query: 654  QQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQ 713
            ++ +Q   DI+R A+ +   S      L +  + EN     +++L    E+ + +    +
Sbjct: 1188 ERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQAKNISQDLE 1247

Query: 714  NRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESAS 773
             +    H    +      E  AS+           + P   ++L  EA  +       A 
Sbjct: 1248 KQAARVHEEAKRAGDKAVEIYASVAQ---------LSPLDSETLENEANNIKME----AE 1294

Query: 774  NMEQLT-RETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTR 832
            N+EQL  ++ +DY      +  K L        G  +      L+ + +  K+LA++  +
Sbjct: 1295 NLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAK 1354

Query: 833  EATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEF 892
            +      EA+    ++L+  D     + V+D     EEA R   K  +++  +T   ++ 
Sbjct: 1355 KGRDTLQEAN-DILNNLKDFD-----RRVNDNKTAAEEALR---KIPAINQTITEANEKT 1405

Query: 893  KRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESIL 952
            +  Q+ LG+   +A +           +  +   A   K+ A+   +       EV ++L
Sbjct: 1406 REAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNML 1465

Query: 953  KNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAG 1012
            K L+E + ++  ++ +A++ M      SQ   +A                +A++AKN   
Sbjct: 1466 KQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAE--------------INARKAKNSVT 1511

Query: 1013 EALEISSEIEQEIGSL---NLEANVTADGALAMEKG---LASLKSEMREVEGELERKELE 1066
              L I +++ +++G L   +L      +G L   K    ++ L  ++ ++E E +++E  
Sbjct: 1512 SLLSIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAKKQEAA 1571

Query: 1067 -FDTNMDAVQMV 1077
              D N D  +++
Sbjct: 1572 IMDYNRDIEEIM 1583


>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
          Length = 1575

 Score =  565 bits (1456), Expect = e-161
 Identities = 278/608 (45%), Positives = 356/608 (58%), Gaps = 27/608 (4%)

Query: 9   CLCFSLLLPAARATSRRE----VCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIH 64
           CL F    P AR T+        C+C+G+S +C FDREL R TG+G RC +C D+T G H
Sbjct: 304 CLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPH 363

Query: 65  CEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLT 124
           CE+C+  FY    R  C PC+C S GSL  +CD++G C+CKP VTG +CDRCLPGFH L+
Sbjct: 364 CERCQENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLS 423

Query: 125 DAGCTQDQRLLDSKCDCDPAGIAGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPE 182
           + GC          C C+PAG    CD  +GRC CK  V G  CDRCR G +NL   NP 
Sbjct: 424 EGGCRP--------CTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPA 475

Query: 183 GCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVFSS 242
           GC+ CFCYGHS  C S+A++ VH I S FHQ  +GW A    GS    QWS     V  S
Sbjct: 476 GCSSCFCYGHSKVCASTAQFQVHHILSDFHQGAEGWWARSVGGSEHPPQWSPN--GVLLS 533

Query: 243 AQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPLMP 302
            +  D     AP KFLG+Q+ SYGQ L   +RV  G   P    + LEG GL ++     
Sbjct: 534 PE--DEEELTAPEKFLGDQRFSYGQPLILTFRVPPGDS-PLPVQLRLEGTGLALSLRHSS 590

Query: 303 LGKTLPCGLTKTYTFRLN-EHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTG--Y 359
           L      G  +    R + +  S + +P L  F ++RLL NLT+LR+R + G    G  +
Sbjct: 591 LSGPQDAGHPREVELRFHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSPGPSPAGPVF 650

Query: 360 IDNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQ 419
           +  V L SARP    PA WVE C CP GY GQFC+ CA GYKR+  + GP+ +C+PC C 
Sbjct: 651 LTEVRLTSARPGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCN 710

Query: 420 GGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRS--CKPCPCHNGFSCSVMPETE 477
             G CDP+TG C          C  C  GFY +P   ++  C+PCPC    +C+ +PE+ 
Sbjct: 711 QHGTCDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESR 770

Query: 478 EVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGR 537
           EVVC +CPPG  G RCE+C DG+FGDP G  G  +PC  CQC+ NVDP+A GNCD L+G 
Sbjct: 771 EVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGH 830

Query: 538 CLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG--SEPVGCRS-DGTCVCK 594
           CL+C+HNT G +C+ C+ G++G  LAP PADKC  C+C+P G  SE + C    G C C 
Sbjct: 831 CLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCL 890

Query: 595 PGFGGPNC 602
           P     +C
Sbjct: 891 PHVTARDC 898



 Score =  182 bits (462), Expect = 2e-45
 Identities = 188/762 (24%), Positives = 304/762 (39%), Gaps = 80/762 (10%)

Query: 384  CPVGYKGQFCQDCASGYKRDSARLGPFG---TCIPCNCQGG------GACDPDTGDCYSG 434
            CP G +G+ C+ C  G+  D   LG FG    C  C C G       G CDP +G C   
Sbjct: 777  CPPGQRGRRCEVCDDGFFGDP--LGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRC 834

Query: 435  DENPDIE-CADCPIGFYNDPHDPR---SCKPCPCHNGFSCSVMPETEEVVCN-NCPPGVT 489
              N   + C  C  GFY     PR    C PC CH   S S     + V    +C P VT
Sbjct: 835  LHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVT 894

Query: 490  GARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIY 549
               C  C  G+F     +  P R C+ C+C+     S    C   TG+C  C     G  
Sbjct: 895  ARDCSRCYPGFF-----DLQPGRGCRSCKCHPL--GSQEDQCHPKTGQCT-CRPGVTGQA 946

Query: 550  CDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE--HGAF 607
            CD+C+ G+FG  +       CRAC C+P+G+    C  +GTCVC+PGF G  C+  H  F
Sbjct: 947  CDRCQLGFFGFSIKG-----CRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNF 1001

Query: 608  ----------SCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAE 657
                       CP+CY  VK +  +   +L   E  +   QG D   P   L+  + +A 
Sbjct: 1002 FLTADGTHCQQCPSCYALVKEEAAKLKARLTLTEGWL---QGSDCGSPWGPLDILLGEAP 1058

Query: 658  QALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVR 717
            +   D+ +   +  GA  +   Q+  +     + + +L  L       +A   +   ++ 
Sbjct: 1059 RG--DVYQGHHLLPGAREAFLEQMMSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLA 1116

Query: 718  DTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQ 777
            D   ++   +  +  + A L +  IP  +    P  +  LA EA  LA SH ++A+ +  
Sbjct: 1117 DLEAVLESSEEEILHAAAILASLEIP-QEGPSQPTKWSHLATEARALARSHRDTATKIAA 1175

Query: 778  LTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQA 837
                    S  + +L+   L           +G V       LE      Q   +    A
Sbjct: 1176 TAWRALLASNTSYALLWNLL-----------EGRVALETQRDLEDRYQEVQAAQKALRTA 1224

Query: 838  EIEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQK 897
              E     +  L  +  V               A   K +A+ L         + K  +K
Sbjct: 1225 VAEVLPEAESVLATVQQVGADTAPYLALLASPGALPQKSRAEDLGL-------KAKALEK 1277

Query: 898  NLGNWKE---EAQQLLQNGKSGREKSDQLLSR----ANLAKSRAQEALSMGNATFYEVES 950
             + +W+    EA + LQ       +  + L++    A  A ++A  ++     T     +
Sbjct: 1278 TVASWQHMATEAARTLQTAAQATLRQTEPLTKLHQEARAALTQASSSVQAATVTVMGART 1337

Query: 951  ILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNG 1010
            +L +L    LQ    K +A    K  S   + ++D   KT+QAER LG+AA  +  AK  
Sbjct: 1338 LLADLEGMKLQFPRPKDQAALQRKADSVSDRLLADTRKKTKQAERMLGNAAPLSSSAKKK 1397

Query: 1011 AGEALEISSEIEQEIGSLNLEANVTADGALAM-EKGLASLKSEMREV-EGELERKELEFD 1068
              EA  ++ +  +   +L  E       A  +  +  A+L+   ++V   E  R+ELE  
Sbjct: 1398 GREAEVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQASQQVLASEARRQELE-- 1455

Query: 1069 TNMDAVQMVITEAQKVDTRAKNAGVTIQDTLNTLDGLLHLMG 1110
                  + V     +++ + + + ++++  + TL  LL  +G
Sbjct: 1456 ----EAERVGAGLSEMEQQIRESRISLEKDIETLSELLARLG 1493



 Score =  115 bits (288), Expect = 2e-25
 Identities = 62/148 (41%), Positives = 80/148 (54%), Gaps = 22/148 (14%)

Query: 53  CLNCNDNTDGIHCEKCKNGFYRH----RERDRCLPCNCNSKGSLSAR--CDN-SGRCSCK 105
           CL C  NT G HCE C+ GFY      R  D+C+PC+C+ +GS+S +  CD  +G+CSC 
Sbjct: 831 CLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCL 890

Query: 106 PGVTGARCDRCLPGFHMLTDA-GCTQDQRLLDSKCDCDPAGI-AGPC--DAGRCVCKPAV 161
           P VT   C RC PGF  L    GC          C C P G     C    G+C C+P V
Sbjct: 891 PHVTARDCSRCYPGFFDLQPGRGC--------RSCKCHPLGSQEDQCHPKTGQCTCRPGV 942

Query: 162 TGERCDRCRSGYYNLDGGNPEGCTQCFC 189
           TG+ CDRC+ G++   G + +GC  C C
Sbjct: 943 TGQACDRCQLGFF---GFSIKGCRACRC 967



 Score = 74.3 bits (181), Expect = 6e-13
 Identities = 49/152 (32%), Positives = 63/152 (41%), Gaps = 19/152 (12%)

Query: 53  CLNCNDNTDGIHCEKCKNGFYRHR-----ERDRCLPCNCNSKGSLSA--RCDN-SGRC-S 103
           C +C     G  CE C +GF+            C  C C+     +A   CD  SG C  
Sbjct: 774 CTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLR 833

Query: 104 CKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAG---PCD--AGRCVCK 158
           C    TG  C+ C  GF+    A    D+ +    C C P G      PCD   G+C C 
Sbjct: 834 CLHNTTGDHCEHCQEGFYGSALAPRPADKCM---PCSCHPQGSVSEQMPCDPVTGQCSCL 890

Query: 159 PAVTGERCDRCRSGYYNLDGGNPEGCTQCFCY 190
           P VT   C RC  G+++L  G   GC  C C+
Sbjct: 891 PHVTARDCSRCYPGFFDLQPG--RGCRSCKCH 920



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 45/149 (30%), Positives = 63/149 (42%), Gaps = 13/149 (8%)

Query: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQC 519
           C C NG +    P+    +   C    TG  CE C   +   P+  G       C PC C
Sbjct: 271 CKC-NGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC 329

Query: 520 NNNVDPSA-SGNCDRLTG---RCLKCIHNTAGIYCDQCKAGYFG-DPLAPNPADKCRACN 574
           +   +         R TG   RC  C  +TAG +C++C+  ++  DP  P     C+ C+
Sbjct: 330 SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP-----CQPCD 384

Query: 575 CNPMGSEPVGCRSDGTCVCKPGFGGPNCE 603
           C   GS  + C   GTC CKP   G  C+
Sbjct: 385 CQSAGSLHLQCDDTGTCACKPTVTGWKCD 413



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 65/254 (25%), Positives = 83/254 (32%), Gaps = 41/254 (16%)

Query: 416 CNCQGGGA-CDPDTGD---CYSGDENPDIECADCPIGFYNDP------HDPRSCKPCPCH 465
           C C G  + C PD      C         +C  C   F + P           C PC C 
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330

Query: 466 N-GFSCSVMPETEEVV-----CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC 519
                C+   E          C++C     G  CE C + ++        P  PCQPC C
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFY-----HWDPRMPCQPCDC 385

Query: 520 NNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG 579
            +    S    CD  TG C  C     G  CD+C  G+            CR C CNP G
Sbjct: 386 QSA--GSLHLQCDD-TGTCA-CKPTVTGWKCDRCLPGFHS-----LSEGGCRPCTCNPAG 436

Query: 580 SEPVGCRSDGTCVCKPGFGGPNCE-----------HGAFSCPACYNQVKIQMDQFMQQLQ 628
           S        G C CK    G  C+           H    C +C+     ++     Q Q
Sbjct: 437 SLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVCASTAQFQ 496

Query: 629 RMEALISKAQGGDG 642
               L    QG +G
Sbjct: 497 VHHILSDFHQGAEG 510



 Score = 64.3 bits (155), Expect = 6e-10
 Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 8/98 (8%)

Query: 28   CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCN 87
            C C+    Q   + + H +TG       C     G  C++C+ GF+    +  C  C C+
Sbjct: 917  CKCHPLGSQ---EDQCHPKTGQ----CTCRPGVTGQACDRCQLGFFGFSIKG-CRACRCS 968

Query: 88   SKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTD 125
              G+ SA+C  +G C C+PG  G +CDRC   F +  D
Sbjct: 969  PLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTAD 1006



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 5/64 (7%)

Query: 541 CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGS-EPVGCRSDGTCVCKPGFGG 599
           C     G +C+ C  GY  +     P   C  C CN  G+ +P    + G CVC     G
Sbjct: 675 CPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGTCDP----NTGICVCSHHTEG 730

Query: 600 PNCE 603
           P+CE
Sbjct: 731 PSCE 734



 Score = 34.7 bits (78), Expect = 0.52
 Identities = 25/90 (27%), Positives = 31/90 (34%), Gaps = 9/90 (10%)

Query: 377  PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDP---DTGDCYS 433
            P   QC C  G  GQ C  C  G+   S +      C  C C   GA      + G C  
Sbjct: 931  PKTGQCTCRPGVTGQACDRCQLGFFGFSIK-----GCRACRCSPLGAASAQCHENGTCVC 985

Query: 434  GDENPDIECADCPIGFYNDPHDPRSCKPCP 463
                   +C  C   F+    D   C+ CP
Sbjct: 986  RPGFEGYKCDRCHDNFFLTA-DGTHCQQCP 1014


>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
          Length = 3075

 Score =  358 bits (919), Expect = 2e-98
 Identities = 235/646 (36%), Positives = 325/646 (50%), Gaps = 94/646 (14%)

Query: 26  EVCDCNGKSRQCIFDRELHRQ-----TGNGFR----CLNCNDNTDGIHCEKCKNGFYR-H 75
           E C+C+ K++ C +D  + +Q     T   FR    C+NC  NT GI+CE C +G+YR H
Sbjct: 325 EACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPH 384

Query: 76  R----ERDRCLPCNCNSKGSLSARC------------DNSGRCSCKPGVTGARCDRCLPG 119
           +    E + C PCNC+  GSLS+ C               G+C CK G TG +CDRC  G
Sbjct: 385 KVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLG 444

Query: 120 FHMLTDAGCTQDQRLLDSKCDCDPAGIAG--PCDAGRCVCKPAVTGERCDRCRSGYYNLD 177
           +         +D     S C C+P G A   PC  G CVCK  V G+ CDRC+ G+YNL 
Sbjct: 445 Y---------KDYPTCVS-CGCNPVGSASDEPC-TGPCVCKENVEGKACDRCKPGFYNLK 493

Query: 178 GGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQ--- 234
             NP GC++CFC+G S  C SS  + V ++ S     + GW       SP K+   Q   
Sbjct: 494 EKNPRGCSECFCFGVSDVC-SSLSWPVGQVNS-----MSGWLVTDLI-SPRKIPSQQDAL 546

Query: 235 --RHQDVFSSA---QRLDPVYF-VAPAKFLGNQQVSYG----QSLSFDYRVDRGGRHPSA 284
             RHQ   ++    QRL P Y+  AP  +LGN+  ++G     ++S+D  V+    +  +
Sbjct: 547 GGRHQVSINNTAVMQRLAPKYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPVETVDSNLMS 606

Query: 285 H-DVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSN----NWSPQLSYFEYRRL 339
           H DVI++G GL ++       + L     + Y   +   P N    +   Q+   +   +
Sbjct: 607 HADVIIKGNGLTLSTQ----AEGLSLQPYEEYLNVVRLVPENFQDFHSKRQIDRDQLMTV 662

Query: 340 LRNLTALRIRATYGEYSTGY--IDNVTL--ISARPVSGAPAPWVEQCICPVGYKGQFCQD 395
           L N+T L IRA Y         +++V+L   S+  +    A  VE C CP GY G  C+ 
Sbjct: 663 LANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVAADVEHCECPQGYTGTSCES 722

Query: 396 CASGYKR-DSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPD-IECADCPIGFYNDP 453
           C SGY R D    G  G C PC C G  A     G C +   N   + C  C  GFY +P
Sbjct: 723 CLSGYYRVDGILFG--GICQPCECHGHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEP 780

Query: 454 H--DPRSCKPCPC-----HNGFSCSV-MPETEEVVCNNCPPGVTGARCELCADGYFGDPF 505
               P  C+PC C      N FS +  + + +EVVC+ C PG +GA CE CADGY+G+P 
Sbjct: 781 SRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPT 840

Query: 506 GEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPN 565
               P   C PC C+ NVDPS +G+CD +TG CLKC+ NT G +C++C  G++GD +   
Sbjct: 841 V---PGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVT-- 895

Query: 566 PADKCRACNCNPMGSEPVGCRSD-GTCVCKPGFGGPNCE---HGAF 607
            A  CRAC C+  GS    C  + G C CKP   G  C+   HG +
Sbjct: 896 -AKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYY 940



 Score =  230 bits (587), Expect = 5e-60
 Identities = 262/1165 (22%), Positives = 448/1165 (38%), Gaps = 160/1165 (13%)

Query: 28   CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCN 87
            CDC      C        +TG    C+ C  +T G+ CE+C++G + +     C  CNC+
Sbjct: 998  CDCPHTQNTC------DPETGE---CV-CPPHTQGVKCEECEDGHWGYDAEVGCQACNCS 1047

Query: 88   SKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGI 146
              GS   RCD  +G C CK    G  CD+C  G+    D             CDCD  G 
Sbjct: 1048 LVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDC----------VPCDCDLRGT 1097

Query: 147  AGPC------------DAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSA 194
            +G              + G C CK  V G +C+ CR G + L   NP GC+ CFC G S 
Sbjct: 1098 SGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSH 1157

Query: 195  SCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVFSSAQ-----RLDPV 249
             C    +Y    +T    Q +    +        +  + Q    +  +A      R +P 
Sbjct: 1158 LCSELEDYVRTPVTLGSDQPLLRVVSQSNLRGTTEGVYYQAPDFLLDAATVRQHIRAEPF 1217

Query: 250  YFVAPAKFLGNQQVSYGQSLSFD---YRVDRGGRHPSAHDVILEGAGLRITAPLMPLGKT 306
            Y+  P +F G+Q ++YG  L +    Y +D  G       V+++G   RI   ++ +   
Sbjct: 1218 YWRLPQQFQGDQLMAYGGKLKYSVAFYSLDGVGTSNFEPQVLIKGG--RIRKQVIYMDAP 1275

Query: 307  LP-CGLTKTYTFRLNEHPSNNW-------SPQLSYFEYRRLLRNLTALRIRATYGE-YST 357
             P  G+ +     + E   N W          ++  ++  +L ++  + I+A+YG+    
Sbjct: 1276 APENGVRQEQEVAMRE---NFWKYFNSVSEKPVTREDFMSVLSDIEYILIKASYGQGLQQ 1332

Query: 358  GYIDNVTLISARPV-----SGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGP--- 409
              I ++++   R           A  +E C+CP G  G  CQDCA GY R     G    
Sbjct: 1333 SRISDISMEVGRKAEKLHPEEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRG 1392

Query: 410  ----FGTCIPCNCQG-GGACDPDTGDCYS-GDENPDIECADCPIGFYNDPHDPRS-CKPC 462
                   C+PC+C      CDP+TG C + GD      C  C  G+Y       S C  C
Sbjct: 1393 PRPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALC 1452

Query: 463  PCHNGFSCSVMPE-----TEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPC 517
             C +    S  P        +  C+ C  G  G  CE C+  Y+G+P     P   CQ C
Sbjct: 1453 ACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNP---QTPGGSCQKC 1509

Query: 518  QCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNP 577
             CN +   S  G+CDR +G+C+ C    +G+ CD+C      +P        C +C+   
Sbjct: 1510 DCNPH--GSVHGDCDRTSGQCV-CRLGASGLRCDEC------EPRHILMETDCVSCDDEC 1560

Query: 578  MGSEPVGCRSDGTCVCKPGFGG----PNCEHGAFSCPACYNQVKIQMDQFMQQLQRMEAL 633
            +G         G  V      G    P            Y Q  +  +   + L +++ L
Sbjct: 1561 VGVLLNDLDEIGDAVLSLNLTGIIPVPYGILSNLENTTKYLQESLLKENMQKDLGKIK-L 1619

Query: 634  ISKAQGGDGVVPD-TELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENSYQ 692
               A+  D +    T +    Q+  +A + I +++Q    A   L + + ++  +    Q
Sbjct: 1620 EGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIERLQMSITEIMEKTTLNQ 1679

Query: 693  SRLDDLKM---TVERVRALGSQYQN--RVRDTHRLITQMQLSLAESEASLGNTNIPASDH 747
            +  +D  +   T++ ++  G+      ++RD  +L     L L  +E  L        ++
Sbjct: 1680 TLDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQ----IQEN 1735

Query: 748  YVGP-NGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLV-----------RK 795
            Y  P    + L + A+ +   H       E L RE E   +++  L+            K
Sbjct: 1736 YQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDK 1795

Query: 796  ALH---------EGVGSGSGSPDGAVVQ--GLVEKLEKTKSLAQQLTREATQAEIEADRS 844
             LH         E +  G G  D A  Q   + + LE  +    +L   + +     D  
Sbjct: 1796 KLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDL 1855

Query: 845  YQHS---------LRLLDSVSRLQGVSDQSFQ-VEEAKRIKQKADS-------LSSLVTR 887
              H           R  D  +  Q ++D  +  +E  + +   A S       + SL+  
Sbjct: 1856 VMHMSQRNAVDLVYRAEDHAAEFQRLADVLYSGLENIRNVSLNATSAAYVHYNIQSLIEE 1915

Query: 888  HMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYE 947
              +  +   + +      ++ L+ NGK+  ++S + L   N   SR    +++      E
Sbjct: 1916 SEELARDAHRTVTETSLLSESLVSNGKAAVQRSSRFLKEGN-NLSRKLPGIAL------E 1968

Query: 948  VESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRA 1007
            +  +      F         +  E++  L  I + + D   KT++   +   +A    R 
Sbjct: 1969 LSELRNKTNRFQENAVEITRQTNESLLILRAIPKGIRDKGAKTKELATSASQSAVSTLRD 2028

Query: 1008 KNG-AGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGE------- 1059
              G + E L  S+ + +   +L     +  D  +A    LA  K +  E++         
Sbjct: 2029 VAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMATL--LAGRKVKDVEIQANLLFDRLK 2086

Query: 1060 -LERKELEFDTNMDAVQMVITEAQK 1083
             L+  E     N+  ++++I++A+K
Sbjct: 2087 PLKMLEENLSRNLSEIKLLISQARK 2111



 Score =  127 bits (320), Expect = 4e-29
 Identities = 85/270 (31%), Positives = 115/270 (42%), Gaps = 63/270 (23%)

Query: 384  CPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG------GACDPDTGDCYSGDEN 437
            C  GY G +C+ CA GY  +    G   +C+PC+C G       G CD  TG+C     N
Sbjct: 819  CAPGYSGAWCERCADGYYGNPTVPGE--SCVPCDCSGNVDPSEAGHCDSVTGECLKCLGN 876

Query: 438  PD-IECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
             D   C  C  GFY D    ++C+ C CH   S S +   E  +C+ C P VTG +C+ C
Sbjct: 877  TDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCD-CKPNVTGQQCDQC 935

Query: 497  ADGYFGDPFGEHGPVRPCQPCQCN-----------------------NNVDPSASG---- 529
              GY+G   G HG    C+PC C+                          D  A G    
Sbjct: 936  LHGYYGLDSG-HG----CRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAY 990

Query: 530  ---------------NCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACN 574
                            CD  TG C+ C  +T G+ C++C+ G++G          C+ACN
Sbjct: 991  QDGSCTPCDCPHTQNTCDPETGECV-CPPHTQGVKCEECEDGHWGYDAEVG----CQACN 1045

Query: 575  CNPMGSEPVGCR-SDGTCVCKPGFGGPNCE 603
            C+ +GS    C    G C CK  FGG  C+
Sbjct: 1046 CSLVGSTHHRCDVVTGHCQCKSKFGGRACD 1075



 Score =  114 bits (284), Expect = 7e-25
 Identities = 56/162 (34%), Positives = 74/162 (45%), Gaps = 17/162 (10%)

Query: 28   CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCN 87
            C+C+ K          H +TG      +C  N  G  C++C +G+Y       C PCNC+
Sbjct: 902  CECHVKGSHSAV---CHLETG----LCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCS 954

Query: 88   SKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA 147
              GS+S  C + G+C C PGV G RCDRC  GF+   D  CT         CDC      
Sbjct: 955  VAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCT--------PCDCPHTQNT 1006

Query: 148  GPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
               + G CVC P   G +C+ C  G++  D     GC  C C
Sbjct: 1007 CDPETGECVCPPHTQGVKCEECEDGHWGYDA--EVGCQACNC 1046



 Score =  111 bits (278), Expect = 3e-24
 Identities = 92/311 (29%), Positives = 116/311 (37%), Gaps = 51/311 (16%)

Query: 382  CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDP---DTGDCYSGDENP 438
            C C     GQ C  C  GY    +  G    C PCNC   G+      D G C+      
Sbjct: 921  CDCKPNVTGQQCDQCLHGYYGLDSGHG----CRPCNCSVAGSVSDGCTDEGQCHCVPGVA 976

Query: 439  DIECADCPIGFYNDPHDPRSCKPCPC-HNGFSCSVMPETEEVVCNNCPPGVTGARCELCA 497
               C  C  GFY   +   SC PC C H   +C   PET E VC   PP   G +CE C 
Sbjct: 977  GKRCDRCAHGFY--AYQDGSCTPCDCPHTQNTCD--PETGECVC---PPHTQGVKCEECE 1029

Query: 498  DGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGY 557
            DG++G    E G    CQ C C+  +  S    CD +TG C +C     G  CDQC  GY
Sbjct: 1030 DGHWGYD-AEVG----CQACNCS--LVGSTHHRCDVVTGHC-QCKSKFGGRACDQCSLGY 1081

Query: 558  FGDPLAPNPADKCRACNCNPMGSEPVGCRSD----------GTCVCKPGFGGP---NCEH 604
               P        C  C+C+  G+    C  +          G C CK    GP    C  
Sbjct: 1082 RDFP-------DCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECRE 1134

Query: 605  GAFS--------CPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQA 656
            G F+        C  C+      +   ++   R    +   Q    VV  + L G  +  
Sbjct: 1135 GTFALRADNPLGCSPCFCSGLSHLCSELEDYVRTPVTLGSDQPLLRVVSQSNLRGTTEGV 1194

Query: 657  EQALQDILRDA 667
                 D L DA
Sbjct: 1195 YYQAPDFLLDA 1205



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 52/182 (28%), Positives = 70/182 (38%), Gaps = 31/182 (17%)

Query: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQC 519
           C C+   S     ET + +   C     G  C  C  GY   P+  G       C+ C C
Sbjct: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329

Query: 520 NNNV-----DPSASGNCDRLT--------GRCLKCIHNTAGIYCDQCKAGYF-GDPLAPN 565
           +N       D S +     L         G C+ C+ NT GI C+ C  GY+    ++P 
Sbjct: 330 HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPY 389

Query: 566 PADKCRACNCNPMGSEPVGCRSD------------GTCVCKPGFGGPNCEH---GAFSCP 610
             + CR CNC+P+GS    C  D            G C CK G+ G  C+    G    P
Sbjct: 390 EDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYP 449

Query: 611 AC 612
            C
Sbjct: 450 TC 451



 Score = 77.4 bits (189), Expect = 7e-14
 Identities = 60/210 (28%), Positives = 86/210 (40%), Gaps = 38/210 (18%)

Query: 381  QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNC-QGGGACDPDTGDCYSGDENPD 439
            QC C  G  G+ C  CA G+          G+C PC+C      CDP+TG+C        
Sbjct: 968  QCHCVPGVAGKRCDRCAHGFYAYQD-----GSCTPCDCPHTQNTCDPETGECVCPPHTQG 1022

Query: 440  IECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETE---EVVCNN--CPPGVTGARCE 494
            ++C +C  G +    +   C+ C      +CS++  T    +VV  +  C     G  C+
Sbjct: 1023 VKCEECEDGHWGYDAEV-GCQAC------NCSLVGSTHHRCDVVTGHCQCKSKFGGRACD 1075

Query: 495  LCADGYFGDPFGEHGPVRPCQPCQCN--------NNVDPSASGNCDRLTGRCLKCIHNTA 546
             C+ GY   P         C PC C+         N++    G C   TG C  C  N  
Sbjct: 1076 QCSLGYRDFP--------DCVPCDCDLRGTSGDACNLEQGLCG-CVEETGAC-PCKENVF 1125

Query: 547  GIYCDQCKAGYFGDPLAPNPADKCRACNCN 576
            G  C++C+ G F    A NP   C  C C+
Sbjct: 1126 GPQCNECREGTFA-LRADNPLG-CSPCFCS 1153



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 65/247 (26%), Positives = 86/247 (34%), Gaps = 69/247 (27%)

Query: 377 PWVE-----QCICPVGYKGQFCQDCASGYKRDSARLGPF---GTCIPCNC---------- 418
           PW E     QC C     G+ C  C  GY +   R G      TC  CNC          
Sbjct: 280 PWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYD 339

Query: 419 ----------------QGGGACDPDTGDCYSGDENPDIECADCPIGFYN----DPHDPRS 458
                           +GGG C     +C        I C  C  G+Y      P++   
Sbjct: 340 ESVAKQKKSLNTAGQFRGGGVCI----NCL--QNTMGINCETCIDGYYRPHKVSPYEDEP 393

Query: 459 CKPCPCHNGFSCSVMPETEEVVCN----------NCPPGVTGARCELCADGYFGDPFGEH 508
           C+PC C    S S +   +++  +           C  G TG +C+ C  GY   P    
Sbjct: 394 CRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYP---- 449

Query: 509 GPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPAD 568
                C  C CN    P  S + +  TG C+ C  N  G  CD+CK G++   L      
Sbjct: 450 ----TCVSCGCN----PVGSASDEPCTGPCV-CKENVEGKACDRCKPGFYN--LKEKNPR 498

Query: 569 KCRACNC 575
            C  C C
Sbjct: 499 GCSECFC 505



 Score = 38.9 bits (89), Expect = 0.027
 Identities = 29/113 (25%), Positives = 40/113 (35%), Gaps = 26/113 (23%)

Query: 101 RCSCKPGVTGARCDRCLPGFHM------LTDAG--------------CTQDQRLLDSKCD 140
           +C C+    G  C+RC PG+H          +G              C  D+ +   K  
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348

Query: 141 CDPAGIAGPCDAGRCV-CKPAVTGERCDRCRSGYYNLDGGNP---EGCTQCFC 189
            + AG       G C+ C     G  C+ C  GYY     +P   E C  C C
Sbjct: 349 LNTAGQFR--GGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNC 399


>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
            sapiens]
          Length = 3118

 Score =  313 bits (802), Expect = 6e-85
 Identities = 230/705 (32%), Positives = 310/705 (43%), Gaps = 150/705 (21%)

Query: 26   EVCDCNGKSRQCIFDRELHRQT----------GNGFRCLNCNDNTDGIHCEKCKNGFYRH 75
            E C+C+GK+ +C +D  + R+           G G  C+NC  NT GI+CE C +GF+R 
Sbjct: 342  EACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGV-CINCTQNTAGINCETCTDGFFRP 400

Query: 76   RERDR-----CLPCNCNSKGSLSARCDNS----------GRCSCKPGVTGARCDRCLPGF 120
            +         C PC+C+  GSL+  C             G C CK G  G  CDRC  G+
Sbjct: 401  KGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460

Query: 121  HMLTDAGCTQDQRLLDSKCDCDPAGIAG--PCDAGRCVCKPAVTGERCDRCRSGYYNLDG 178
                D             C+C   G     PC  G C+CK  V G  C RC+SG++NL  
Sbjct: 461  TGYPDC----------KACNCSGLGSKNEDPC-FGPCICKENVEGGDCSRCKSGFFNLQE 509

Query: 179  GNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNG----SPAKLQWSQ 234
             N +GC +CFC G S  C+SS  ++  KI     QD+ GW      G    +P +     
Sbjct: 510  DNWKGCDECFCSGVSNRCQSSY-WTYGKI-----QDMSGWYLTDLPGRIRVAPQQDDLDS 563

Query: 235  RHQDVFSSAQRLDPV----YFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDV--- 287
              Q   S+A+    +    Y+ APA +LGN+  + G  L+F    D          V   
Sbjct: 564  PQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQL 623

Query: 288  --ILEGAGLRITAP-----LMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRR-- 338
              ILEG  L I+       L P  +     L K  +F ++           ++F  RR  
Sbjct: 624  MIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHG----------THFPVRRKE 673

Query: 339  ---LLRNLTALRIRATY--GEYSTGYIDNVTLISA--RPVSGAPAPWVEQCICPVGYKGQ 391
               +L NL  + ++ TY  G  +   + +V L SA   P  G+ A  VE C CP GY G 
Sbjct: 674  FMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGS 733

Query: 392  FCQDCASGYKRDSARLGPFGTCIPCNCQGGG-ACDPDTGDCYS-GDENPDIECADCPIGF 449
             C+ C   ++R +  +   G C PC C G   +CD  TG+C +  D      C  C  GF
Sbjct: 734  SCESCWPRHRRVNGTIFG-GICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGF 792

Query: 450  YNDPHDPRS--CKPCPC-----HNGFSCSV-MPETEEVVCNNCPPGVTGARCELCADGYF 501
            Y +P    S  C+PC C      N FS +  +  +  ++C+ CP G TG RCE CA+GYF
Sbjct: 793  YGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYF 852

Query: 502  GDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDP 561
            G P    G    CQPCQCN+N+D S  G+CD L+G CL C   T G YC+ C  GYFGD 
Sbjct: 853  GQPSVPGGS---CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDA 909

Query: 562  L-APN--------------------------------PADKCRA-------------CNC 575
            + A N                                  DKC+A             CNC
Sbjct: 910  VDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNC 969

Query: 576  NPMGSEPVGCRSDGTCVCKPGFGGPNCE---HGAFS-----CPAC 612
            N  GS+   C   G C C+PG  G  C+   HG F+     C AC
Sbjct: 970  NSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTAC 1014



 Score =  240 bits (612), Expect = 6e-63
 Identities = 280/1159 (24%), Positives = 454/1159 (39%), Gaps = 188/1159 (16%)

Query: 28   CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCN 87
            C+C+     C        +TG   RC+ C  NT G  C KC    + H     C  CNC+
Sbjct: 1014 CECSHLGNNC------DPKTG---RCI-CPPNTIGEKCSKCAPNTWGHSITTGCKACNCS 1063

Query: 88   SKGSLSARCD-NSGRCSCKPGVTGARCDRCLPG------------FHMLTDAGCTQDQRL 134
            + GSL  +C+ N+G+C+C P  +GA+C  C  G            F   TDA     +  
Sbjct: 1064 TVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSET- 1122

Query: 135  LDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSA 194
               KC C           G+C CK  V G  CDRCR G + LD  NP GC+ C+C+G + 
Sbjct: 1123 --KKCSCSD-------QTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTT 1173

Query: 195  SCRSSAEYSVHKITSTFHQDV-----DGWKAVQRNGSPAKLQWSQRHQDVFSSAQRLDPV 249
             C  +       +T    Q +     +  +     G   +      H D+      L+P 
Sbjct: 1174 QCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPF 1233

Query: 250  YFVAPAKFLGNQQVSYGQSLS----FDYRVDRGGRHPSAHDVILEGAGLRITAPLMPLGK 305
            Y+  P +F G + ++YG  L     F+ R + G    +   +I  G        +  +  
Sbjct: 1234 YWKLPEQFEGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAA 1293

Query: 306  TLPCGLTKTYTFRLNEHPSNNWSPQ------LSYFEYRRLLRNLTALRIRATYGEYST-G 358
             L   LT+ +   + E     +         ++  ++  +L ++  + I+ATYG +    
Sbjct: 1294 PLIGQLTR-HEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQS 1352

Query: 359  YIDNVTLISARPVSGA----PAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCI 414
             I  +++  A    G     PA  +E+C CP+GY G  C+ C  G+ R  ++        
Sbjct: 1353 RISEISMEVAEQGRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQ-------- 1404

Query: 415  PCNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMP 474
                 GG    P  G                            +C PC C NG S    P
Sbjct: 1405 ----PGGRTPGPTLG----------------------------TCVPCQC-NGHSSLCDP 1431

Query: 475  ETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC-----NNNVDPS--A 527
            ET   +C NC     G  CE CA GY+G      G    CQ C C     +NN  PS  A
Sbjct: 1432 ETS--ICQNCQHHTAGDFCERCALGYYGIV---KGLPNDCQQCACPLISSSNNFSPSCVA 1486

Query: 528  SGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRS 587
             G  D    RC  C     G YC++C  GY G P   NP   C+ C C+P GS PV C  
Sbjct: 1487 EGLDDY---RCTACPRGYEGQYCERCAPGYTGSP--GNPGGSCQECECDPYGSLPVPCDP 1541

Query: 588  -DGTCVCKPGFGGPNCE-------HGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQ- 638
              G C C+PG  G  C+          + C  C ++        +  L R+E ++     
Sbjct: 1542 VTGFCTCRPGATGRKCDGCKHWHAREGWECVFCGDEC---TGLLLGDLARLEQMVMSINL 1598

Query: 639  GGDGVVPDTELEGRMQQAEQALQDIL-------RDAQISEGASRSLGLQLAKVRSQENSY 691
             G    P   L G ++   Q L+ +L       R  Q++EG   +L  ++ ++ ++    
Sbjct: 1599 TGPLPAPYKMLYG-LENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKV 1657

Query: 692  ----QSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDH 747
                +    D + T  R ++LG   +   RD    + +  + L E   +LG  +     +
Sbjct: 1658 TADGEQTGQDAERTNTRAKSLGEFIKELARDA-EAVNEKAIKLNE---TLGTRDEAFERN 1713

Query: 748  YVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGS 807
              G    K + Q    L   ++E+    +++  +    ++  L  V+K   E  G     
Sbjct: 1714 LEGLQ--KEIDQMIKELRRKNLET---QKEIAEDELVAAEALLKKVKKLFGESRGENE-- 1766

Query: 808  PDGAVVQGLVEKLEKTKSL---AQQLTREATQAEIEADRSYQHSLRLLDSV-SRLQGVSD 863
                + + L EKL   K+    A  L REAT    EA+R +  + + + ++  + + V  
Sbjct: 1767 ---EMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVES 1823

Query: 864  QSFQVE----EAKRIKQKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREK 919
               Q+E    E   I  +A+ L+  +   +D  +  Q  L    EE    + +  S   K
Sbjct: 1824 GKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDD-LSQEIK 1882

Query: 920  SDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYI 979
              +L  + + A+S A        A   +  ++L  + +   +  N    A  A K  S I
Sbjct: 1883 DRKLAEKVSQAESHA--------AQLNDSSAVLDGILD---EAKNISFNATAAFKAYSNI 1931

Query: 980  SQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE--IEQEIGSLNLEANVTAD 1037
               + +A    ++A+      A +A +   G    L+  ++  +++    LN EA   A+
Sbjct: 1932 KDYIDEAEKVAKEAK----DLAHEATKLATGPRGLLKEDAKGCLQKSFRILN-EAKKLAN 1986

Query: 1038 GALAMEKGLASLKSEMREVE---GELERKELEFDTNMDAV--------QMVITEAQKVDT 1086
                 E  L  LK+ +   +   G+L R   +    + A+        Q V  +A++ + 
Sbjct: 1987 DVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDKARQAND 2046

Query: 1087 RAKNAGVTIQDTLNTLDGL 1105
             AK+    I +    LDGL
Sbjct: 2047 TAKDVLAQITELHQNLDGL 2065



 Score =  127 bits (319), Expect = 6e-29
 Identities = 82/238 (34%), Positives = 103/238 (43%), Gaps = 30/238 (12%)

Query: 383  ICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDENP 438
            IC  G  G++C+ CA GY  D+        C PC C  GG+    C   TG C       
Sbjct: 888  ICKPGTTGRYCELCADGYFGDAVDAK---NCQPCRCNAGGSFSEVCHSQTGQCECRANVQ 944

Query: 439  DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCAD 498
               C  C  G +      R C PC C N F        E   C  C PGVTG +C+ CA 
Sbjct: 945  GQRCDKCKAGTFG-LQSARGCVPCNC-NSFGSKSFDCEESGQCW-CQPGVTGKKCDRCAH 1001

Query: 499  GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
            GYF   F E G    C  C+C++        NCD  TGRC+ C  NT G  C +C    +
Sbjct: 1002 GYFN--FQEGG----CTACECSH-----LGNNCDPKTGRCI-CPPNTIGEKCSKCAPNTW 1049

Query: 559  GDPLAPNPADKCRACNCNPMGSEPVGCR-SDGTCVCKPGFGG---PNCEHGAFSCPAC 612
            G  +       C+ACNC+ +GS    C  + G C C P F G     C  G ++ P C
Sbjct: 1050 GHSITTG----CKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRC 1103



 Score =  120 bits (300), Expect = 9e-27
 Identities = 64/182 (35%), Positives = 80/182 (43%), Gaps = 17/182 (9%)

Query: 8    CCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEK 67
            C LC       A      + C CN       F    H QTG       C  N  G  C+K
Sbjct: 898  CELCADGYFGDAVDAKNCQPCRCNAGGS---FSEVCHSQTGQ----CECRANVQGQRCDK 950

Query: 68   CKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAG 127
            CK G +  +    C+PCNCNS GS S  C+ SG+C C+PGVTG +CDRC  G+    + G
Sbjct: 951  CKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGG 1010

Query: 128  CTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQC 187
            CT         C+C   G       GRC+C P   GE+C +C    +        GC  C
Sbjct: 1011 CT--------ACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWG--HSITTGCKAC 1060

Query: 188  FC 189
             C
Sbjct: 1061 NC 1062



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 72/260 (27%), Positives = 105/260 (40%), Gaps = 55/260 (21%)

Query: 381  QCICPVGYKGQFCQDCASG-YKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGD 435
            QC C    +GQ C  C +G +   SAR      C+PCNC   G+    C+ ++G C+   
Sbjct: 936  QCECRANVQGQRCDKCKAGTFGLQSAR-----GCVPCNCNSFGSKSFDCE-ESGQCWCQP 989

Query: 436  ENPDIECADCPIGFYNDPHDPRSCKPCPC-HNGFSCSVMPETEEVVCNNCPPGVTGARCE 494
                 +C  C  G++N       C  C C H G +C   P+T   +   CPP   G +C 
Sbjct: 990  GVTGKKCDRCAHGYFN--FQEGGCTACECSHLGNNCD--PKTGRCI---CPPNTIGEKCS 1042

Query: 495  LCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCK 554
             CA   +G     H     C+ C C  +   S    C+  TG+C  C    +G  C +C 
Sbjct: 1043 KCAPNTWG-----HSITTGCKACNC--STVGSLDFQCNVNTGQC-NCHPKFSGAKCTECS 1094

Query: 555  AGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD----------GTCVCKPGFGGPNCEH 604
             G++  P       +C  C+C   G++   C S+          G C CK    G +C+ 
Sbjct: 1095 RGHWNYP-------RCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDR 1147

Query: 605  ---GAF--------SCPACY 613
               G F         C +CY
Sbjct: 1148 CRPGKFGLDAKNPLGCSSCY 1167



 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 61/203 (30%), Positives = 77/203 (37%), Gaps = 26/203 (12%)

Query: 381  QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPD 439
            QC C  G  G+ C  CA GY          G C  C C   G  CDP TG C        
Sbjct: 984  QCWCQPGVTGKKCDRCAHGYFNFQE-----GGCTACECSHLGNNCDPKTGRCICPPNTIG 1038

Query: 440  IECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADG 499
             +C+ C    +        CK C C    S           CN C P  +GA+C  C+ G
Sbjct: 1039 EKCSKCAPNTWGHSITT-GCKACNCSTVGSLDFQCNVNTGQCN-CHPKFSGAKCTECSRG 1096

Query: 500  YFGDPFGEHGPVRPCQPCQC-------NNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQ 552
            ++  P         C  C C             +   +C   TG+C  C  N  GI+CD+
Sbjct: 1097 HWNYP--------RCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCT-CKVNVEGIHCDR 1147

Query: 553  CKAGYFGDPLAPNPADKCRACNC 575
            C+ G FG   A NP   C +C C
Sbjct: 1148 CRPGKFGLD-AKNPLG-CSSCYC 1168



 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 53/184 (28%), Positives = 76/184 (41%), Gaps = 34/184 (18%)

Query: 462 CPCH-NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQ 518
           C C+ +  +C + P T +  C  C     G  C+ C  G+   P+  G       C+ C 
Sbjct: 287 CICYGHARACPLDPATNKSRCE-CEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACN 345

Query: 519 CNNNVDPSA-SGNCDRLT------------GRCLKCIHNTAGIYCDQCKAGYFGDP-LAP 564
           C+   +      N  R              G C+ C  NTAGI C+ C  G+F    ++P
Sbjct: 346 CHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSP 405

Query: 565 NPADKCRACNCNPMGSEPVGCRSD----------GTCVCKPGFGGPNCEH------GAFS 608
           N    C+ C+C+P+GS    C  D          G+C CK GFGG +C+       G   
Sbjct: 406 NYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD 465

Query: 609 CPAC 612
           C AC
Sbjct: 466 CKAC 469



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 66/237 (27%), Positives = 87/237 (36%), Gaps = 50/237 (21%)

Query: 375 PAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGT---CIPCNCQG-GGACDPDT-- 428
           PA    +C C     G  C  C  G+ +   R G F T   C  CNC G    C  D   
Sbjct: 300 PATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENV 359

Query: 429 ----------------GDCYSGDEN-PDIECADCPIGFYN----DPHDPRSCKPCPCHNG 467
                           G C +  +N   I C  C  GF+      P+ PR C+PC C   
Sbjct: 360 ARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPI 419

Query: 468 FSCSVMPETEEVVCN--------NCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC 519
            S + +   +E            +C  G  G  C+ CA GY G P         C+ C C
Sbjct: 420 GSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYP--------DCKACNC 471

Query: 520 NNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCN 576
           +       S N D   G C+ C  N  G  C +CK+G+F   L  +    C  C C+
Sbjct: 472 SG----LGSKNEDPCFGPCI-CKENVEGGDCSRCKSGFFN--LQEDNWKGCDECFCS 521



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 31/117 (26%), Positives = 41/117 (35%), Gaps = 28/117 (23%)

Query: 98  NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCD-CDPAGIAGPC------ 150
           N  RC C+    G  CD+C PGFH       T    L  ++C+ C+  G A  C      
Sbjct: 303 NKSRCECEHNTCGDSCDQCCPGFHQKPWRAGT---FLTKTECEACNCHGKAEECYYDENV 359

Query: 151 --------------DAGRCV-CKPAVTGERCDRCRSGYYNLDG---GNPEGCTQCFC 189
                           G C+ C     G  C+ C  G++   G     P  C  C C
Sbjct: 360 ARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHC 416



 Score = 35.0 bits (79), Expect = 0.39
 Identities = 20/80 (25%), Positives = 31/80 (38%), Gaps = 19/80 (23%)

Query: 9    CLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKC 68
            C CF     A    S  + C C+ ++ QC                  C  N +GIHC++C
Sbjct: 1106 CDCFLPGTDATTCDSETKKCSCSDQTGQC-----------------TCKVNVEGIHCDRC 1148

Query: 69   KNGFYRHRERD--RCLPCNC 86
            + G +    ++   C  C C
Sbjct: 1149 RPGKFGLDAKNPLGCSSCYC 1168


>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
            sapiens]
          Length = 3122

 Score =  313 bits (802), Expect = 6e-85
 Identities = 230/705 (32%), Positives = 310/705 (43%), Gaps = 150/705 (21%)

Query: 26   EVCDCNGKSRQCIFDRELHRQT----------GNGFRCLNCNDNTDGIHCEKCKNGFYRH 75
            E C+C+GK+ +C +D  + R+           G G  C+NC  NT GI+CE C +GF+R 
Sbjct: 342  EACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGV-CINCTQNTAGINCETCTDGFFRP 400

Query: 76   RERDR-----CLPCNCNSKGSLSARCDNS----------GRCSCKPGVTGARCDRCLPGF 120
            +         C PC+C+  GSL+  C             G C CK G  G  CDRC  G+
Sbjct: 401  KGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460

Query: 121  HMLTDAGCTQDQRLLDSKCDCDPAGIAG--PCDAGRCVCKPAVTGERCDRCRSGYYNLDG 178
                D             C+C   G     PC  G C+CK  V G  C RC+SG++NL  
Sbjct: 461  TGYPDC----------KACNCSGLGSKNEDPC-FGPCICKENVEGGDCSRCKSGFFNLQE 509

Query: 179  GNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNG----SPAKLQWSQ 234
             N +GC +CFC G S  C+SS  ++  KI     QD+ GW      G    +P +     
Sbjct: 510  DNWKGCDECFCSGVSNRCQSSY-WTYGKI-----QDMSGWYLTDLPGRIRVAPQQDDLDS 563

Query: 235  RHQDVFSSAQRLDPV----YFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDV--- 287
              Q   S+A+    +    Y+ APA +LGN+  + G  L+F    D          V   
Sbjct: 564  PQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQL 623

Query: 288  --ILEGAGLRITAP-----LMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRR-- 338
              ILEG  L I+       L P  +     L K  +F ++           ++F  RR  
Sbjct: 624  MIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHG----------THFPVRRKE 673

Query: 339  ---LLRNLTALRIRATY--GEYSTGYIDNVTLISA--RPVSGAPAPWVEQCICPVGYKGQ 391
               +L NL  + ++ TY  G  +   + +V L SA   P  G+ A  VE C CP GY G 
Sbjct: 674  FMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGS 733

Query: 392  FCQDCASGYKRDSARLGPFGTCIPCNCQGGG-ACDPDTGDCYS-GDENPDIECADCPIGF 449
             C+ C   ++R +  +   G C PC C G   +CD  TG+C +  D      C  C  GF
Sbjct: 734  SCESCWPRHRRVNGTIFG-GICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGF 792

Query: 450  YNDPHDPRS--CKPCPC-----HNGFSCSV-MPETEEVVCNNCPPGVTGARCELCADGYF 501
            Y +P    S  C+PC C      N FS +  +  +  ++C+ CP G TG RCE CA+GYF
Sbjct: 793  YGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYF 852

Query: 502  GDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDP 561
            G P    G    CQPCQCN+N+D S  G+CD L+G CL C   T G YC+ C  GYFGD 
Sbjct: 853  GQPSVPGGS---CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDA 909

Query: 562  L-APN--------------------------------PADKCRA-------------CNC 575
            + A N                                  DKC+A             CNC
Sbjct: 910  VDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNC 969

Query: 576  NPMGSEPVGCRSDGTCVCKPGFGGPNCE---HGAFS-----CPAC 612
            N  GS+   C   G C C+PG  G  C+   HG F+     C AC
Sbjct: 970  NSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTAC 1014



 Score =  240 bits (612), Expect = 6e-63
 Identities = 280/1159 (24%), Positives = 454/1159 (39%), Gaps = 188/1159 (16%)

Query: 28   CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCN 87
            C+C+     C        +TG   RC+ C  NT G  C KC    + H     C  CNC+
Sbjct: 1014 CECSHLGNNC------DPKTG---RCI-CPPNTIGEKCSKCAPNTWGHSITTGCKACNCS 1063

Query: 88   SKGSLSARCD-NSGRCSCKPGVTGARCDRCLPG------------FHMLTDAGCTQDQRL 134
            + GSL  +C+ N+G+C+C P  +GA+C  C  G            F   TDA     +  
Sbjct: 1064 TVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSET- 1122

Query: 135  LDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSA 194
               KC C           G+C CK  V G  CDRCR G + LD  NP GC+ C+C+G + 
Sbjct: 1123 --KKCSCSD-------QTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTT 1173

Query: 195  SCRSSAEYSVHKITSTFHQDV-----DGWKAVQRNGSPAKLQWSQRHQDVFSSAQRLDPV 249
             C  +       +T    Q +     +  +     G   +      H D+      L+P 
Sbjct: 1174 QCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPF 1233

Query: 250  YFVAPAKFLGNQQVSYGQSLS----FDYRVDRGGRHPSAHDVILEGAGLRITAPLMPLGK 305
            Y+  P +F G + ++YG  L     F+ R + G    +   +I  G        +  +  
Sbjct: 1234 YWKLPEQFEGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAA 1293

Query: 306  TLPCGLTKTYTFRLNEHPSNNWSPQ------LSYFEYRRLLRNLTALRIRATYGEYST-G 358
             L   LT+ +   + E     +         ++  ++  +L ++  + I+ATYG +    
Sbjct: 1294 PLIGQLTR-HEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQS 1352

Query: 359  YIDNVTLISARPVSGA----PAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCI 414
             I  +++  A    G     PA  +E+C CP+GY G  C+ C  G+ R  ++        
Sbjct: 1353 RISEISMEVAEQGRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQ-------- 1404

Query: 415  PCNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMP 474
                 GG    P  G                            +C PC C NG S    P
Sbjct: 1405 ----PGGRTPGPTLG----------------------------TCVPCQC-NGHSSLCDP 1431

Query: 475  ETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC-----NNNVDPS--A 527
            ET   +C NC     G  CE CA GY+G      G    CQ C C     +NN  PS  A
Sbjct: 1432 ETS--ICQNCQHHTAGDFCERCALGYYGIV---KGLPNDCQQCACPLISSSNNFSPSCVA 1486

Query: 528  SGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRS 587
             G  D    RC  C     G YC++C  GY G P   NP   C+ C C+P GS PV C  
Sbjct: 1487 EGLDDY---RCTACPRGYEGQYCERCAPGYTGSP--GNPGGSCQECECDPYGSLPVPCDP 1541

Query: 588  -DGTCVCKPGFGGPNCE-------HGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQ- 638
              G C C+PG  G  C+          + C  C ++        +  L R+E ++     
Sbjct: 1542 VTGFCTCRPGATGRKCDGCKHWHAREGWECVFCGDEC---TGLLLGDLARLEQMVMSINL 1598

Query: 639  GGDGVVPDTELEGRMQQAEQALQDIL-------RDAQISEGASRSLGLQLAKVRSQENSY 691
             G    P   L G ++   Q L+ +L       R  Q++EG   +L  ++ ++ ++    
Sbjct: 1599 TGPLPAPYKMLYG-LENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKV 1657

Query: 692  ----QSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDH 747
                +    D + T  R ++LG   +   RD    + +  + L E   +LG  +     +
Sbjct: 1658 TADGEQTGQDAERTNTRAKSLGEFIKELARDA-EAVNEKAIKLNE---TLGTRDEAFERN 1713

Query: 748  YVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGS 807
              G    K + Q    L   ++E+    +++  +    ++  L  V+K   E  G     
Sbjct: 1714 LEGLQ--KEIDQMIKELRRKNLET---QKEIAEDELVAAEALLKKVKKLFGESRGENE-- 1766

Query: 808  PDGAVVQGLVEKLEKTKSL---AQQLTREATQAEIEADRSYQHSLRLLDSV-SRLQGVSD 863
                + + L EKL   K+    A  L REAT    EA+R +  + + + ++  + + V  
Sbjct: 1767 ---EMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVES 1823

Query: 864  QSFQVE----EAKRIKQKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREK 919
               Q+E    E   I  +A+ L+  +   +D  +  Q  L    EE    + +  S   K
Sbjct: 1824 GKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDD-LSQEIK 1882

Query: 920  SDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYI 979
              +L  + + A+S A        A   +  ++L  + +   +  N    A  A K  S I
Sbjct: 1883 DRKLAEKVSQAESHA--------AQLNDSSAVLDGILD---EAKNISFNATAAFKAYSNI 1931

Query: 980  SQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE--IEQEIGSLNLEANVTAD 1037
               + +A    ++A+      A +A +   G    L+  ++  +++    LN EA   A+
Sbjct: 1932 KDYIDEAEKVAKEAK----DLAHEATKLATGPRGLLKEDAKGCLQKSFRILN-EAKKLAN 1986

Query: 1038 GALAMEKGLASLKSEMREVE---GELERKELEFDTNMDAV--------QMVITEAQKVDT 1086
                 E  L  LK+ +   +   G+L R   +    + A+        Q V  +A++ + 
Sbjct: 1987 DVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDKARQAND 2046

Query: 1087 RAKNAGVTIQDTLNTLDGL 1105
             AK+    I +    LDGL
Sbjct: 2047 TAKDVLAQITELHQNLDGL 2065



 Score =  127 bits (319), Expect = 6e-29
 Identities = 82/238 (34%), Positives = 103/238 (43%), Gaps = 30/238 (12%)

Query: 383  ICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDENP 438
            IC  G  G++C+ CA GY  D+        C PC C  GG+    C   TG C       
Sbjct: 888  ICKPGTTGRYCELCADGYFGDAVDAK---NCQPCRCNAGGSFSEVCHSQTGQCECRANVQ 944

Query: 439  DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCAD 498
               C  C  G +      R C PC C N F        E   C  C PGVTG +C+ CA 
Sbjct: 945  GQRCDKCKAGTFG-LQSARGCVPCNC-NSFGSKSFDCEESGQCW-CQPGVTGKKCDRCAH 1001

Query: 499  GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
            GYF   F E G    C  C+C++        NCD  TGRC+ C  NT G  C +C    +
Sbjct: 1002 GYFN--FQEGG----CTACECSH-----LGNNCDPKTGRCI-CPPNTIGEKCSKCAPNTW 1049

Query: 559  GDPLAPNPADKCRACNCNPMGSEPVGCR-SDGTCVCKPGFGG---PNCEHGAFSCPAC 612
            G  +       C+ACNC+ +GS    C  + G C C P F G     C  G ++ P C
Sbjct: 1050 GHSITTG----CKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRC 1103



 Score =  120 bits (300), Expect = 9e-27
 Identities = 64/182 (35%), Positives = 80/182 (43%), Gaps = 17/182 (9%)

Query: 8    CCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEK 67
            C LC       A      + C CN       F    H QTG       C  N  G  C+K
Sbjct: 898  CELCADGYFGDAVDAKNCQPCRCNAGGS---FSEVCHSQTGQ----CECRANVQGQRCDK 950

Query: 68   CKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAG 127
            CK G +  +    C+PCNCNS GS S  C+ SG+C C+PGVTG +CDRC  G+    + G
Sbjct: 951  CKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGG 1010

Query: 128  CTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQC 187
            CT         C+C   G       GRC+C P   GE+C +C    +        GC  C
Sbjct: 1011 CT--------ACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWG--HSITTGCKAC 1060

Query: 188  FC 189
             C
Sbjct: 1061 NC 1062



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 72/260 (27%), Positives = 105/260 (40%), Gaps = 55/260 (21%)

Query: 381  QCICPVGYKGQFCQDCASG-YKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGD 435
            QC C    +GQ C  C +G +   SAR      C+PCNC   G+    C+ ++G C+   
Sbjct: 936  QCECRANVQGQRCDKCKAGTFGLQSAR-----GCVPCNCNSFGSKSFDCE-ESGQCWCQP 989

Query: 436  ENPDIECADCPIGFYNDPHDPRSCKPCPC-HNGFSCSVMPETEEVVCNNCPPGVTGARCE 494
                 +C  C  G++N       C  C C H G +C   P+T   +   CPP   G +C 
Sbjct: 990  GVTGKKCDRCAHGYFN--FQEGGCTACECSHLGNNCD--PKTGRCI---CPPNTIGEKCS 1042

Query: 495  LCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCK 554
             CA   +G     H     C+ C C  +   S    C+  TG+C  C    +G  C +C 
Sbjct: 1043 KCAPNTWG-----HSITTGCKACNC--STVGSLDFQCNVNTGQC-NCHPKFSGAKCTECS 1094

Query: 555  AGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD----------GTCVCKPGFGGPNCEH 604
             G++  P       +C  C+C   G++   C S+          G C CK    G +C+ 
Sbjct: 1095 RGHWNYP-------RCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDR 1147

Query: 605  ---GAF--------SCPACY 613
               G F         C +CY
Sbjct: 1148 CRPGKFGLDAKNPLGCSSCY 1167



 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 61/203 (30%), Positives = 77/203 (37%), Gaps = 26/203 (12%)

Query: 381  QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPD 439
            QC C  G  G+ C  CA GY          G C  C C   G  CDP TG C        
Sbjct: 984  QCWCQPGVTGKKCDRCAHGYFNFQE-----GGCTACECSHLGNNCDPKTGRCICPPNTIG 1038

Query: 440  IECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADG 499
             +C+ C    +        CK C C    S           CN C P  +GA+C  C+ G
Sbjct: 1039 EKCSKCAPNTWGHSITT-GCKACNCSTVGSLDFQCNVNTGQCN-CHPKFSGAKCTECSRG 1096

Query: 500  YFGDPFGEHGPVRPCQPCQC-------NNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQ 552
            ++  P         C  C C             +   +C   TG+C  C  N  GI+CD+
Sbjct: 1097 HWNYP--------RCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCT-CKVNVEGIHCDR 1147

Query: 553  CKAGYFGDPLAPNPADKCRACNC 575
            C+ G FG   A NP   C +C C
Sbjct: 1148 CRPGKFGLD-AKNPLG-CSSCYC 1168



 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 53/184 (28%), Positives = 76/184 (41%), Gaps = 34/184 (18%)

Query: 462 CPCH-NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQ 518
           C C+ +  +C + P T +  C  C     G  C+ C  G+   P+  G       C+ C 
Sbjct: 287 CICYGHARACPLDPATNKSRCE-CEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACN 345

Query: 519 CNNNVDPSA-SGNCDRLT------------GRCLKCIHNTAGIYCDQCKAGYFGDP-LAP 564
           C+   +      N  R              G C+ C  NTAGI C+ C  G+F    ++P
Sbjct: 346 CHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSP 405

Query: 565 NPADKCRACNCNPMGSEPVGCRSD----------GTCVCKPGFGGPNCEH------GAFS 608
           N    C+ C+C+P+GS    C  D          G+C CK GFGG +C+       G   
Sbjct: 406 NYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD 465

Query: 609 CPAC 612
           C AC
Sbjct: 466 CKAC 469



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 66/237 (27%), Positives = 87/237 (36%), Gaps = 50/237 (21%)

Query: 375 PAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGT---CIPCNCQG-GGACDPDT-- 428
           PA    +C C     G  C  C  G+ +   R G F T   C  CNC G    C  D   
Sbjct: 300 PATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENV 359

Query: 429 ----------------GDCYSGDEN-PDIECADCPIGFYN----DPHDPRSCKPCPCHNG 467
                           G C +  +N   I C  C  GF+      P+ PR C+PC C   
Sbjct: 360 ARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPI 419

Query: 468 FSCSVMPETEEVVCN--------NCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC 519
            S + +   +E            +C  G  G  C+ CA GY G P         C+ C C
Sbjct: 420 GSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYP--------DCKACNC 471

Query: 520 NNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCN 576
           +       S N D   G C+ C  N  G  C +CK+G+F   L  +    C  C C+
Sbjct: 472 SG----LGSKNEDPCFGPCI-CKENVEGGDCSRCKSGFFN--LQEDNWKGCDECFCS 521



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 31/117 (26%), Positives = 41/117 (35%), Gaps = 28/117 (23%)

Query: 98  NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCD-CDPAGIAGPC------ 150
           N  RC C+    G  CD+C PGFH       T    L  ++C+ C+  G A  C      
Sbjct: 303 NKSRCECEHNTCGDSCDQCCPGFHQKPWRAGT---FLTKTECEACNCHGKAEECYYDENV 359

Query: 151 --------------DAGRCV-CKPAVTGERCDRCRSGYYNLDG---GNPEGCTQCFC 189
                           G C+ C     G  C+ C  G++   G     P  C  C C
Sbjct: 360 ARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHC 416



 Score = 35.0 bits (79), Expect = 0.39
 Identities = 20/80 (25%), Positives = 31/80 (38%), Gaps = 19/80 (23%)

Query: 9    CLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKC 68
            C CF     A    S  + C C+ ++ QC                  C  N +GIHC++C
Sbjct: 1106 CDCFLPGTDATTCDSETKKCSCSDQTGQC-----------------TCKVNVEGIHCDRC 1148

Query: 69   KNGFYRHRERD--RCLPCNC 86
            + G +    ++   C  C C
Sbjct: 1149 RPGKFGLDAKNPLGCSSCYC 1168


>gi|21264602 laminin alpha 5 [Homo sapiens]
          Length = 3695

 Score =  301 bits (772), Expect = 2e-81
 Identities = 314/1206 (26%), Positives = 465/1206 (38%), Gaps = 210/1206 (17%)

Query: 53   CLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGS---LSARCD-NSGRCSCKPGV 108
            CL C   T G H                C  CNC+  G        CD +SG+C C+P V
Sbjct: 1509 CLLCQPQTFGCH------------PLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNV 1556

Query: 109  TGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPCD--AGRCVCKPAVTGER 165
            TG RCD C PGFH                 CDC  AG A G CD   G+C CK  V G +
Sbjct: 1557 TGRRCDTCSPGFHGYPRC----------RPCDCHEAGTAPGVCDPLTGQCYCKENVQGPK 1606

Query: 166  CDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAV---- 221
            CD+C  G ++LD  NP+GCT+CFC+G +  CRSS+       T     D++GW  +    
Sbjct: 1607 CDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSS------YTRQEFVDMEGWVLLSTDR 1660

Query: 222  -----QRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVD 276
                 +R      L+   RH    +  +    +Y+ AP  +LG++  SYG +L ++   +
Sbjct: 1661 QVVPHERQPGTEMLRADLRHVPE-AVPEAFPELYWQAPPSYLGDRVSSYGGTLRYELHSE 1719

Query: 277  --RGGRH---PSAHDVILEGAGLRIT--APLMPLGKTLPCGLTKTYTFRLNEHPSNNWSP 329
              RG       S  DV+L+G  + IT   P  P    +  G  +          + N   
Sbjct: 1720 TQRGDVFVPMESRPDVVLQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRN--- 1776

Query: 330  QLSYFEYRRLLRNLTALRIRATYGEYSTG-YIDNVTLISARPVS-GAPAPWVEQCICPVG 387
             +S  E   +L +L  L+IRA + + S+  ++  V L  A P   GA A  VE C+CP  
Sbjct: 1777 TVSREELMMVLASLEQLQIRALFSQISSAVFLRRVALEVASPAGQGALASNVELCLCPAS 1836

Query: 388  YKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPD-IECADC 445
            Y+G  CQ+CA G+ RD   L   G C+PC C G    C P +G C     N +   C  C
Sbjct: 1837 YRGDSCQECAPGFYRDVKGLF-LGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERC 1895

Query: 446  PIGFYNDPHDPRS-CKPCPC-----HNGFSCSVMPETEEVVCNNCPPGVTGARCELCADG 499
              GF +   DP + C  CPC      N F+   +       C  C PG  GA CE CA G
Sbjct: 1896 QAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCL-CKPGYAGASCERCAPG 1954

Query: 500  YFGDPFGEHGPVRPCQPCQCNNNVDPSAS-GNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
            +FG+P         CQPC C+ N DP+    +CD LTG C  C+ +T G  C+ C  G++
Sbjct: 1955 FFGNPLVLGSS---CQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFY 2011

Query: 559  GDPLAPNPADKCRACNCNPMGSEPV--------------------------------GCR 586
            G+ L P     C  C+C P G+E                                  GCR
Sbjct: 2012 GNALLPG---NCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCR 2068

Query: 587  ---------------SDGTCVCKPGFGGPNC-----------EHGAFSCPA--------- 611
                             G C C+PG  GP C           E G   C           
Sbjct: 2069 PCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQCPGGRCDPHT 2128

Query: 612  --CYNQVKIQMDQFMQQLQRMEALISKAQGGDGV------------VPDTELEGRMQQAE 657
              C     +  ++     Q+ +  +     G  +            + D E  G +    
Sbjct: 2129 GRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHCVVLLLDDLERAGALL--- 2185

Query: 658  QALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVR 717
             A+ + LR    S  A   L    A +   ++  +S L     T +++  L  Q  +  +
Sbjct: 2186 PAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQ 2245

Query: 718  DTHRL-------ITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVE 770
            D  RL         Q    LA +EA+LG+     +           L  +   L  ++  
Sbjct: 2246 DARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLAAIRAVDRTLSELMSQTGHLGLANA- 2304

Query: 771  SASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKL-EKTKSLAQQ 829
            SA + EQL R   +  +  L    +A   G    +   + A  Q L+ ++ E+  SL ++
Sbjct: 2305 SAPSGEQLLRTLAEVER--LLWEMRARDLGAPQAAAEAELAAAQRLLARVQEQLSSLWEE 2362

Query: 830  LTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQ-----------VEEAKRIKQK- 877
                ATQ     DR  QH   L+D    L    D + +           +EEA + KQ+ 
Sbjct: 2363 NQALATQTR---DRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEALQRKQEL 2419

Query: 878  -ADSLSSLVTRH-----MDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAK 931
              D+ +   T H     +    R   +L   KEE ++L  +    R    Q +   + A 
Sbjct: 2420 SRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFSPAG 2479

Query: 932  SRAQEALSMGNATFYEVESILKNLREFDLQVD-----NRKAEAEEAMKRLSYISQKVSDA 986
            S+ +  +    A   ++  +  NL    L V+      R  EA  A  R+    Q   DA
Sbjct: 2480 SKLR-LVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDA 2538

Query: 987  SDKT-QQAERALGSAAAD--AQRAKNGAGEALEISSEIEQEIGSLNLEANVTADGALAME 1043
            + +  QQA+    +        RA+     +  +   + QE   L L           + 
Sbjct: 2539 AGQALQQADHTWATVVRQGLVDRAQQLLANSTALEEAMLQEQQRLGL-----------VW 2587

Query: 1044 KGLASLKSEMREVEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNAGVTIQDTLNTLD 1103
              L   ++++R+V  + ++ E         + M   E  K    AK      QDT   + 
Sbjct: 2588 AALQGARTQLRDVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAAEAQDTATRVQ 2647

Query: 1104 GLLHLM 1109
              L  M
Sbjct: 2648 SQLQAM 2653



 Score =  251 bits (640), Expect = 4e-66
 Identities = 192/658 (29%), Positives = 267/658 (40%), Gaps = 140/658 (21%)

Query: 72   FYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDA-GCT 129
            FY +  R    PC C+  G+    C+   G+C C   V G  C RC  G+    +   C 
Sbjct: 1430 FYNNGAR----PCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCD 1485

Query: 130  QDQRLLD---SKCDCDPAGIAGPC------------------------------------ 150
               RL D    +C C P  I   C                                    
Sbjct: 1486 CGARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDT 1545

Query: 151  DAGRCVCKPAVTGERCDRCRSGY------------------------------------- 173
            D+G+C C+P VTG RCD C  G+                                     
Sbjct: 1546 DSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGP 1605

Query: 174  ---------YNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAV--- 221
                     ++LD  NP+GCT+CFC+G +  CRSS+       T     D++GW  +   
Sbjct: 1606 KCDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSS------YTRQEFVDMEGWVLLSTD 1659

Query: 222  ------QRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFD--- 272
                  +R      L+   RH    +  +    +Y+ AP  +LG++  SYG +L ++   
Sbjct: 1660 RQVVPHERQPGTEMLRADLRHVPE-AVPEAFPELYWQAPPSYLGDRVSSYGGTLRYELHS 1718

Query: 273  --YRVDRGGRHPSAHDVILEGAGLRIT--APLMPLGKTLPCGLTKTYTFRLNEHPSNNWS 328
               R D      S  DV+L+G  + IT   P  P    +  G  +          + N  
Sbjct: 1719 ETQRGDVFVPMESRPDVVLQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRN-- 1776

Query: 329  PQLSYFEYRRLLRNLTALRIRATYGEYSTG-YIDNVTLISARPV-SGAPAPWVEQCICPV 386
              +S  E   +L +L  L+IRA + + S+  ++  V L  A P   GA A  VE C+CP 
Sbjct: 1777 -TVSREELMMVLASLEQLQIRALFSQISSAVFLRRVALEVASPAGQGALASNVELCLCPA 1835

Query: 387  GYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPD-IECAD 444
             Y+G  CQ+CA G+ RD   L   G C+PC C G    C P +G C     N +   C  
Sbjct: 1836 SYRGDSCQECAPGFYRDVKGLF-LGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCER 1894

Query: 445  CPIGFYNDPHDPRS-CKPCPC-----HNGFSCSVMPETEEVVCNNCPPGVTGARCELCAD 498
            C  GF +   DP + C  CPC      N F+   +       C  C PG  GA CE CA 
Sbjct: 1895 CQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQC-LCKPGYAGASCERCAP 1953

Query: 499  GYFGDPFGEHGPVRPCQPCQCNNNVDPS-ASGNCDRLTGRCLKCIHNTAGIYCDQCKAGY 557
            G+FG+P         CQPC C+ N DP+    +CD LTG C  C+ +T G  C+ C  G+
Sbjct: 1954 GFFGNPLVLGS---SCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGF 2010

Query: 558  FGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGG---PNCEHGAFSCPAC 612
            +G+ L P     C  C+C P G+E     S G C+CK G  G     C+ G F    C
Sbjct: 2011 YGNALLPG---NCTRCDCTPCGTEACDPHS-GHCLCKAGVTGRRCDRCQEGHFGFDGC 2064



 Score =  125 bits (313), Expect = 3e-28
 Identities = 88/273 (32%), Positives = 113/273 (41%), Gaps = 55/273 (20%)

Query: 382 CI-CPVGYKGQFCQDCASG-YKRDSARLGPFGTCIPCNCQGG---GACDPDTGDCYSGDE 436
           CI C     G  C+ C  G Y+  +  L     C  CNC+     G C+  TG CY    
Sbjct: 393 CIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPN 452

Query: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCH-NGFSCSVMPETEEVVCNN------------ 483
                C  C  GF   P    SC P P   N     V+P  + V C+             
Sbjct: 453 FSGERCDVCAEGFTGFP----SCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRK 508

Query: 484 --------CPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLT 535
                   C P   G  CELCA G++G           CQPCQC++     A   CD  T
Sbjct: 509 DPRVGRCLCKPNFQGTHCELCAPGFYGPG---------CQPCQCSS--PGVADDRCDPDT 557

Query: 536 GRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKP 595
           G+C +C     G  CD+C  GYF  PL       C+ C C+P G+ P GC   G C+C+P
Sbjct: 558 GQC-RCRVGFEGATCDRCAPGYFHFPL-------CQLCGCSPAGTLPEGCDEAGRCLCQP 609

Query: 596 GFGGPNCE------HGAFSCPACYNQVKIQMDQ 622
            F GP+C+      HG  +C AC    +  +DQ
Sbjct: 610 EFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQ 642



 Score =  115 bits (287), Expect = 3e-25
 Identities = 64/173 (36%), Positives = 88/173 (50%), Gaps = 33/173 (19%)

Query: 26  EVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCN 85
           + C C+ +         L +  G G  C  C     G  C++C  GF+       C+PC+
Sbjct: 630 QACTCDPRGA-------LDQLCGAGGLC-RCRPGYTGTACQECSPGFHGFPS---CVPCH 678

Query: 86  CNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLT--DAGCTQDQRLLDSKCDCD 142
           C+++GSL A CD  SG+CSC+P VTG RCD C+PG +     +AG             C 
Sbjct: 679 CSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAG------------SCH 726

Query: 143 PAGIAGPCDAGR------CVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
           PAG+A P D         C+C+  V G  CDRC+ G++ L   NPEGCT+C C
Sbjct: 727 PAGLA-PVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSC 778



 Score =  114 bits (286), Expect = 4e-25
 Identities = 79/260 (30%), Positives = 106/260 (40%), Gaps = 54/260 (20%)

Query: 381 QCICPVGYKGQFCQDCASGY-------------KRDSARLGPFGTCIPCNCQGGG----A 423
           +C C   + G+ C  CA G+                  ++ P G  + C+C   G    A
Sbjct: 446 RCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNA 505

Query: 424 C--DPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVC 481
           C  DP  G C          C  C  GFY        C+PC C +        + +   C
Sbjct: 506 CRKDPRVGRCLCKPNFQGTHCELCAPGFYGP-----GCQPCQCSSPGVADDRCDPDTGQC 560

Query: 482 NNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSAS--GNCDRLTGRCL 539
             C  G  GA C+ CA GYF  P         CQ C C+    P+ +    CD   GRCL
Sbjct: 561 R-CRVGFEGATCDRCAPGYFHFPL--------CQLCGCS----PAGTLPEGCDE-AGRCL 606

Query: 540 KCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGG 599
            C    AG +CD+C+ GY G P        C+AC C+P G+    C + G C C+PG+ G
Sbjct: 607 -CQPEFAGPHCDRCRPGYHGFP-------NCQACTCDPRGALDQLCGAGGLCRCRPGYTG 658

Query: 600 PNCE------HGAFSCPACY 613
             C+      HG  SC  C+
Sbjct: 659 TACQECSPGFHGFPSCVPCH 678



 Score =  111 bits (277), Expect = 4e-24
 Identities = 67/178 (37%), Positives = 82/178 (46%), Gaps = 31/178 (17%)

Query: 15  LLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYR 74
           +LPA +  +    CDC+    Q        R+     RCL C  N  G HCE C  GFY 
Sbjct: 485 VLPAGQIVN----CDCSAAGTQ----GNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYG 535

Query: 75  HRERDRCLPCNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQR 133
                 C PC C+S G    RCD ++G+C C+ G  GA CDRC PG+             
Sbjct: 536 ----PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFP--------- 582

Query: 134 LLDSKCDCDPAG-IAGPCD-AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
            L   C C PAG +   CD AGRC+C+P   G  CDRCR GY+         C  C C
Sbjct: 583 -LCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGF-----PNCQACTC 634



 Score =  110 bits (276), Expect = 6e-24
 Identities = 73/232 (31%), Positives = 94/232 (40%), Gaps = 25/232 (10%)

Query: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG----ACDPDTGDCYSGDEN 437
           C C  GY G  CQ+C+ G+         F +C+PC+C   G    ACDP +G C      
Sbjct: 650 CRCRPGYTGTACQECSPGFHG-------FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRV 702

Query: 438 PDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEV-VCNNCPPGVTGARCELC 496
             + C  C  G YN P+    C+   CH      V P   E  V   C   V G  C+ C
Sbjct: 703 TGLRCDTCVPGAYNFPY----CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRC 758

Query: 497 ADGYFG-DPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKA 555
             G++G  P    G    C  C C+          C   TG+C  C  +  G  C  CK 
Sbjct: 759 KPGFWGLSPSNPEG----CTRCSCDLRGTLGGVAECQPGTGQCF-CKPHVCGQACASCKD 813

Query: 556 GYFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCEHGA 606
           G+FG  L       CR+C C+  G+    C    G C C+P   GP C   A
Sbjct: 814 GFFG--LDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPA 863



 Score =  105 bits (263), Expect = 2e-22
 Identities = 62/200 (31%), Positives = 89/200 (44%), Gaps = 35/200 (17%)

Query: 19  ARATSRREVCDCNGKSRQCIFDRELHRQTGN---------GFRCLNCNDNTDGIHCEKCK 69
           A + +  + C+C G +  C +D E+ R+  +         G  C++C  +T G++CE+C 
Sbjct: 350 ANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCL 409

Query: 70  NGFYRHRERDR-----CLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHML- 123
            GFYR           C  CNC S  +     D +GRC C+P  +G RCD C  GF    
Sbjct: 410 PGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFP 469

Query: 124 ------TDAGCTQDQRLLDSK---CDCDPAGIAGPC-----DAGRCVCKPAVTGERCDRC 169
                 + +  T++Q L   +   CDC  AG  G         GRC+CKP   G  C+ C
Sbjct: 470 SCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELC 529

Query: 170 RSGYYNLDGGNPEGCTQCFC 189
             G+Y        GC  C C
Sbjct: 530 APGFYG------PGCQPCQC 543



 Score =  101 bits (251), Expect = 4e-21
 Identities = 75/247 (30%), Positives = 98/247 (39%), Gaps = 47/247 (19%)

Query: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCY 432
           P V +C+C   ++G  C+ CA G+       GP   C PC C   G     CDPDTG C 
Sbjct: 510 PRVGRCLCKPNFQGTHCELCAPGF------YGP--GCQPCQCSSPGVADDRCDPDTGQCR 561

Query: 433 SGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPE-TEEVVCNNCPPGVTGA 491
                    C  C  G+++ P     C+ C C        +PE  +E     C P   G 
Sbjct: 562 CRVGFEGATCDRCAPGYFHFP----LCQLCGCS---PAGTLPEGCDEAGRCLCQPEFAGP 614

Query: 492 RCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRL--TGRCLKCIHNTAGIY 549
            C+ C  GY G P         CQ C C    DP   G  D+L   G   +C     G  
Sbjct: 615 HCDRCRPGYHGFP--------NCQACTC----DP--RGALDQLCGAGGLCRCRPGYTGTA 660

Query: 550 CDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCE---HG 605
           C +C  G+ G P        C  C+C+  GS    C    G C C+P   G  C+    G
Sbjct: 661 CQECSPGFHGFP-------SCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPG 713

Query: 606 AFSCPAC 612
           A++ P C
Sbjct: 714 AYNFPYC 720



 Score = 97.4 bits (241), Expect = 6e-20
 Identities = 70/240 (29%), Positives = 92/240 (38%), Gaps = 51/240 (21%)

Query: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG----ACDPDTGDCY 432
           P   QC C VG++G  C  CA GY         F  C  C C   G     CD + G C 
Sbjct: 555 PDTGQCRCRVGFEGATCDRCAPGYFH-------FPLCQLCGCSPAGTLPEGCD-EAGRCL 606

Query: 433 SGDENPDIECADCPIGFYNDPH------DPRSCKPCPCHNGFSCSVMPETEEVVCNNCPP 486
              E     C  C  G++  P+      DPR      C  G  C             C P
Sbjct: 607 CQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLC------------RCRP 654

Query: 487 GVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTA 546
           G TG  C+ C+ G+ G P         C PC C  + + S    CD  +G+C  C     
Sbjct: 655 GYTGTACQECSPGFHGFP--------SCVPCHC--SAEGSLHAACDPRSGQC-SCRPRVT 703

Query: 547 GIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVG---CRSDGTCVCKPGFGGPNCE 603
           G+ CD C  G +  P        C A +C+P G  PV      +   C+C+    GP+C+
Sbjct: 704 GLRCDTCVPGAYNFPY-------CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCD 756



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 48/174 (27%), Positives = 70/174 (40%), Gaps = 23/174 (13%)

Query: 462 CPCH-NGFSCSVMPETE--EVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQP 516
           C CH +  +C     T+   + C  C     G  C+ C  G+   P+          CQ 
Sbjct: 300 CVCHGHADACDAKDPTDPFRLQCT-CQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358

Query: 517 CQCNNNV-----DPS-----ASGNCDRLT---GRCLKCIHNTAGIYCDQCKAGYFGDPLA 563
           C C  +      DP      AS + D      G C+ C H+T G+ C++C  G++  P  
Sbjct: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418

Query: 564 P-NPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE---HGAFSCPACY 613
           P +    CR CNC    ++       G C C+P F G  C+    G    P+CY
Sbjct: 419 PLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCY 472



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 10/86 (11%)

Query: 46  QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCNSKGSLSARCD-NSGRC 102
           Q G G +C  C  +  G  C  CK+GF+   + D   C  C C+  G+L   C+  +G C
Sbjct: 791 QPGTG-QCF-CKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVC 848

Query: 103 SCKPGVTGARC-----DRCLPGFHML 123
            C+P   G  C     D  LP  H L
Sbjct: 849 RCRPNTQGPTCSEPARDHYLPDLHHL 874



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 31/113 (27%), Positives = 43/113 (38%), Gaps = 26/113 (23%)

Query: 101 RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPC---------- 150
           +C+C+    G  CDRC PGF+       T +       C+C   G A  C          
Sbjct: 321 QCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNC--YGHATDCYYDPEVDRRR 378

Query: 151 ----------DAGRCV-CKPAVTGERCDRCRSGYY---NLDGGNPEGCTQCFC 189
                       G C+ C+   TG  C+RC  G+Y   N    +P  C +C C
Sbjct: 379 ASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNC 431



 Score = 40.0 bits (92), Expect = 0.012
 Identities = 26/96 (27%), Positives = 36/96 (37%), Gaps = 19/96 (19%)

Query: 135 LDSKCDCDPAGIAGPCDAG--------RCVCKPAVTGERCDRCRSGYYN-----LDGGNP 181
           +  +C C   G A  CDA         +C C+    G  CDRC  G+           + 
Sbjct: 296 IGGRCVCH--GHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSA 353

Query: 182 EGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDG 217
             C  C CYGH+  C    E    + +    Q +DG
Sbjct: 354 NECQSCNCYGHATDCYYDPEVDRRRAS----QSLDG 385



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 24/60 (40%), Positives = 26/60 (43%), Gaps = 8/60 (13%)

Query: 377 PWVEQCICPVGYKGQFCQDCASG-YKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDC 431
           P   QC C     GQ C  C  G +  D A    FG C  C C  GGA    C+P TG C
Sbjct: 792 PGTGQCFCKPHVCGQACASCKDGFFGLDQADY--FG-CRSCRCDIGGALGQSCEPRTGVC 848


>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
          Length = 3277

 Score =  245 bits (625), Expect = 2e-64
 Identities = 241/925 (26%), Positives = 375/925 (40%), Gaps = 129/925 (13%)

Query: 56   CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSA---RCD-NSGRCSCKPGVTGA 111
            C   T    CE C+   +       C  CNC+ +G++ A    CD +SG+C CKP +TG 
Sbjct: 1328 CPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGR 1387

Query: 112  RCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPCD--AGRCVCKPAVTGERCDR 168
            +CDRC  GF+   +             C+C+  G   G CD   G C+CK  V G  C+ 
Sbjct: 1388 QCDRCASGFYRFPEC----------VPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNV 1437

Query: 169  CRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPA 228
            CR G ++LD  N +GCT CFC+G +  C SS     HK  + F  D+ GW     +    
Sbjct: 1438 CREGSFHLDPANLKGCTSCFCFGVNNQCHSS-----HKRRTKF-VDMLGWHLETADRVDI 1491

Query: 229  KLQWSQRHQDVFSSAQRLDPVY----FVAPAKFLGNQQVSYG-----QSLSFDYRVDRGG 279
             + ++     + +  Q L        +VAP  +LG++  SYG     Q+ SF    D   
Sbjct: 1492 PVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVL 1551

Query: 280  RHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRL 339
                  DV L G  + I        +       + +    N   +++ +P +S  E   +
Sbjct: 1552 LEKKP-DVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAP-VSREELMTV 1609

Query: 340  LRNLTALRIRATY-GEYSTGYIDNVTLISARPV-SGAPAPWVEQCICPVGYKGQFCQDCA 397
            L  L  +RI+  Y  E     +  V L  A    SG  A  VE C CP  Y G  CQ C+
Sbjct: 1610 LSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCS 1669

Query: 398  SGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPDIE-CADCPIGFY-NDPH 454
             GY RD   L   G C+PCNC G    C   +G C +   N   E C  C  G+Y N  H
Sbjct: 1670 PGYYRDHKGLYT-GRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVH 1728

Query: 455  DPRSCKPCPCH--NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVR 512
               SC+ CPC   N F+   +    +V C+ C  G TG +CE CA GYFG+P    G   
Sbjct: 1729 G--SCRACPCPHTNSFATGCVVNGGDVRCS-CKAGYTGTQCERCAPGYFGNPQKFGG--- 1782

Query: 513  PCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRA 572
             CQPC CN+N      G+C  LTG C+                    +P   +PA++C  
Sbjct: 1783 SCQPCSCNSN---GQLGSCHPLTGDCIN------------------QEPKDSSPAEECDD 1821

Query: 573  C-NCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAF-SCPACYNQVKIQMDQFMQQLQRM 630
            C +C       +    +   + K    G +   G          Q K   +Q +     +
Sbjct: 1822 CDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAI 1881

Query: 631  EALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENS 690
                SK +G         LE  +    Q  + +   AQ++   +++L   + +       
Sbjct: 1882 SNHGSKIEG---------LERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKE 1932

Query: 691  YQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNI---PASDH 747
               ++ ++   V  +  + +  +    + + L   ++ SL E EA L +       A+  
Sbjct: 1933 LDVKIKNVIRNVHMLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQ 1992

Query: 748  YVGPNGFKSLAQEATRLAESHVESASNMEQ----------------------LTRETEDY 785
                NG     + A    +  V+  ++++                       + +  ++Y
Sbjct: 1993 AKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEY 2052

Query: 786  SKQALSL--VRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTR----------- 832
             K A SL   R+ L + V   S S   A    LVE+ EK     Q+L +           
Sbjct: 2053 EKLAASLNEARQELSDKVRELSRS---AGKTSLVEEAEKHARSLQELAKQLEEIKRNASG 2109

Query: 833  -EATQAEIEADRSYQHSLRLL----DSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTR 887
             E  +  ++A  +Y++ L  +    D+ +R    S+ + Q    + + +KA +LSS   +
Sbjct: 2110 DELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDK 2169

Query: 888  HMDEFKRTQKNLGNWKEEAQQLLQN 912
             ++E K TQK L   K+E    L N
Sbjct: 2170 LLNEAKMTQKKL---KQEVSPALNN 2191



 Score =  120 bits (302), Expect = 5e-27
 Identities = 69/201 (34%), Positives = 99/201 (49%), Gaps = 34/201 (16%)

Query: 17  PAARATSRR-EVCDCNGKSRQCIFDRELHRQTGN---------GFRCLNCNDNTDGIHCE 66
           PAA   S   E C+C+G +  C +D ++ RQ  +         G  C+NC  NT G++CE
Sbjct: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403

Query: 67  KCKNGFYRH-----RERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH 121
           +C  G+YR         D C+PC+C+ + +       SGRC CKP   G  C++C  G++
Sbjct: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCE-QGSGRCHCKPNFHGDNCEKCAIGYY 462

Query: 122 ML----------TDAGCTQDQRLLDSK-CDCDPAGIAGP-CDA-GRCVCKPAVTGERCDR 168
                            ++D    D K CDC+  G+    CDA GRC+C+P V G RCD 
Sbjct: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDT 522

Query: 169 CRSGYYNLDGGNPEGCTQCFC 189
           CRSG+Y+        C  C+C
Sbjct: 523 CRSGFYSF-----PICQACWC 538



 Score =  107 bits (268), Expect = 5e-23
 Identities = 56/140 (40%), Positives = 73/140 (52%), Gaps = 14/140 (10%)

Query: 52  RCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTG 110
           RCL C    +G  C+ C++GFY       C  C C++ GS    C + +G+C C+PGVTG
Sbjct: 508 RCL-CRPGVEGPRCDTCRSGFYSF---PICQACWCSALGSYQMPCSSVTGQCECRPGVTG 563

Query: 111 ARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCR 170
            RCDRCL G +               S   CDPAG     + G C CK  V G  C RC+
Sbjct: 564 QRCDRCLSGAYDFPHCQ--------GSSSACDPAGTINS-NLGYCQCKLHVEGPTCSRCK 614

Query: 171 SGYYNLDGGNPEGCTQCFCY 190
             Y+NLD  NP GC++C C+
Sbjct: 615 LLYWNLDKENPSGCSECKCH 634



 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 22/158 (13%)

Query: 22   TSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRC 81
            T R   C+CNG S QC        Q G+G  C+NC  NT G HCE+C+ G+Y +     C
Sbjct: 1681 TGRCVPCNCNGHSNQC--------QDGSGI-CVNCQHNTAGEHCERCQEGYYGNAVHGSC 1731

Query: 82   LPCNCNSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSK 138
              C C    S +  C  +G   RCSCK G TG +C+RC PG+      G  Q        
Sbjct: 1732 RACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF-----GNPQKFGGSCQP 1786

Query: 139  CDCDPAGIAGPCD--AGRCV---CKPAVTGERCDRCRS 171
            C C+  G  G C    G C+    K +   E CD C S
Sbjct: 1787 CSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 1824



 Score = 96.3 bits (238), Expect = 1e-19
 Identities = 80/276 (28%), Positives = 108/276 (39%), Gaps = 58/276 (21%)

Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPF---GTCIPCNCQGGGA---CDPDT------ 428
           +C C     G+ C  C +GY +   R   +     C  CNC G  +    DPD       
Sbjct: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQAS 377

Query: 429 ----------GDCYSGDEN-PDIECADCPIGFYND---PHD-PRSCKPCPC--HNGFSCS 471
                     G C +   N   + C  C  G+Y     P D P  C PC C   +   C 
Sbjct: 378 LNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGC- 436

Query: 472 VMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQ-----------CN 520
              E     C +C P   G  CE CA GY+  PF    P+ P                C+
Sbjct: 437 ---EQGSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCD 492

Query: 521 NNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGS 580
            N++      CD   GRCL C     G  CD C++G++  P+       C+AC C+ +GS
Sbjct: 493 CNLEGVLPEICD-AHGRCL-CRPGVEGPRCDTCRSGFYSFPI-------CQACWCSALGS 543

Query: 581 EPVGCRS-DGTCVCKPGFGGPNCEH---GAFSCPAC 612
             + C S  G C C+PG  G  C+    GA+  P C
Sbjct: 544 YQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHC 579



 Score = 94.0 bits (232), Expect = 7e-19
 Identities = 65/217 (29%), Positives = 87/217 (40%), Gaps = 40/217 (18%)

Query: 414  IPCNCQGGGA----CDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFS 469
            +PC C   GA    C P+ G C         +C  C  G Y  P     CKPC C     
Sbjct: 1264 LPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR----CKPCSCGRRL- 1318

Query: 470  CSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN-VDPSAS 528
            C  M       C  CPP     +CE+C    F        P+  C+ C C+      +A 
Sbjct: 1319 CEEMTGQ----CR-CPPRTVRPQCEVCETHSFS-----FHPMAGCEGCNCSRRGTIEAAM 1368

Query: 529  GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RS 587
              CDR +G+C +C     G  CD+C +G++  P       +C  CNCN  G+EP  C   
Sbjct: 1369 PECDRDSGQC-RCKPRITGRQCDRCASGFYRFP-------ECVPCNCNRDGTEPGVCDPG 1420

Query: 588  DGTCVCKPGFGGPN---CEHGAF--------SCPACY 613
             G C+CK    G     C  G+F         C +C+
Sbjct: 1421 TGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCF 1457



 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 62/197 (31%), Positives = 82/197 (41%), Gaps = 24/197 (12%)

Query: 381  QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
            QC C     G+ C  CA+G+         F  C PC+C G   C+  TG C         
Sbjct: 1284 QCPCQPNVIGRQCTRCATGHY-------GFPRCKPCSC-GRRLCEEMTGQCRCPPRTVRP 1335

Query: 441  ECADCPIGFYNDPHDPRSCKPCPC-HNGFSCSVMPETEEVVCN-NCPPGVTGARCELCAD 498
            +C  C    ++  H    C+ C C   G   + MPE +       C P +TG +C+ CA 
Sbjct: 1336 QCEVCETHSFSF-HPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCAS 1394

Query: 499  GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
            G++  P         C PC CN   D +  G CD  TG CL C  N  G  C+ C+ G F
Sbjct: 1395 GFYRFP--------ECVPCNCNR--DGTEPGVCDPGTGACL-CKENVEGTECNVCREGSF 1443

Query: 559  GDPLAPNPADKCRACNC 575
               L P     C +C C
Sbjct: 1444 --HLDPANLKGCTSCFC 1458



 Score = 87.4 bits (215), Expect = 7e-17
 Identities = 74/259 (28%), Positives = 99/259 (38%), Gaps = 76/259 (29%)

Query: 382 CI-CPVGYKGQFCQDCASGYKRDSARLGPFGT-------CIPCNC--QGGGACDPDTGDC 431
           CI C     G  C+ CA GY R      P+G        CIPC+C  +    C+  +G C
Sbjct: 390 CINCQHNTAGVNCEQCAKGYYR------PYGVPVDAPDGCIPCSCDPEHADGCEQGSGRC 443

Query: 432 YSGDENPDIECADCPIGFYNDP---------------HDP--RSCKPCPCHNGFSCSVMP 474
           +         C  C IG+YN P                DP     K C C+      V+P
Sbjct: 444 HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLE---GVLP 500

Query: 475 ETEEVVCNN-----CPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASG 529
           E    +C+      C PGV G RC+ C  G++  P         CQ C C      SA G
Sbjct: 501 E----ICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI--------CQACWC------SALG 542

Query: 530 N----CDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC 585
           +    C  +TG+C +C     G  CD+C +G +  P     +  C          +P G 
Sbjct: 543 SYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDFPHCQGSSSAC----------DPAGT 591

Query: 586 RSD--GTCVCKPGFGGPNC 602
            +   G C CK    GP C
Sbjct: 592 INSNLGYCQCKLHVEGPTC 610



 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 52/171 (30%), Positives = 73/171 (42%), Gaps = 22/171 (12%)

Query: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQC 519
           C C+       +   E++    C     G  C+ C  GY    +          C+ C C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358

Query: 520 NNNV-----DP-----SASGNCDRL---TGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
           + +      DP      AS N   +    G C+ C HNTAG+ C+QC  GY+     P  
Sbjct: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418

Query: 567 A-DKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
           A D C  C+C+P  ++  GC +  G C CKP F G NCE    G ++ P C
Sbjct: 419 APDGCIPCSCDPEHAD--GCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFC 467



 Score = 74.3 bits (181), Expect = 6e-13
 Identities = 70/246 (28%), Positives = 92/246 (37%), Gaps = 46/246 (18%)

Query: 381 QCICPVGYKGQFCQDCASGYKRDS--ARLGPFGTCIP------------CNCQGGGACDP 426
           +C C   + G  C+ CA GY       R+  F    P            C+C   G   P
Sbjct: 442 RCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVL-P 500

Query: 427 DTGD------CYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV 480
           +  D      C  G E P   C  C  GFY+ P     C+ C C +      MP +    
Sbjct: 501 EICDAHGRCLCRPGVEGP--RCDTCRSGFYSFP----ICQACWC-SALGSYQMPCSSVTG 553

Query: 481 CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK 540
              C PGVTG RC+ C  G +  P  + G    C P           +G  +   G C +
Sbjct: 554 QCECRPGVTGQRCDRCLSGAYDFPHCQ-GSSSACDP-----------AGTINSNLGYC-Q 600

Query: 541 CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG--SEPVGCR-SDGTCVCKPGF 597
           C  +  G  C +CK  Y+   L       C  C C+  G  S    CR  DG C CK   
Sbjct: 601 CKLHVEGPTCSRCKLLYWN--LDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHV 658

Query: 598 GGPNCE 603
           GG +C+
Sbjct: 659 GGDSCD 664



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 52/177 (29%), Positives = 73/177 (41%), Gaps = 41/177 (23%)

Query: 447  IGFYNDPHDPRSCKPCPCH----NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFG 502
            + FY+     +   PC CH     G  CS  PE  +  C    P V G +C  CA G++G
Sbjct: 1256 VAFYH-----KGALPCECHPTGATGPHCS--PEGGQCPCQ---PNVIGRQCTRCATGHYG 1305

Query: 503  DPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPL 562
             P         C+PC C   +       C+ +TG+C +C   T    C+ C+   F    
Sbjct: 1306 FP--------RCKPCSCGRRL-------CEEMTGQC-RCPPRTVRPQCEVCETHSF---- 1345

Query: 563  APNPADKCRACNCNPMG----SEPVGCRSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
            + +P   C  CNC+  G    + P   R  G C CKP   G  C+    G +  P C
Sbjct: 1346 SFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPEC 1402



 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 50/180 (27%), Positives = 71/180 (39%), Gaps = 13/180 (7%)

Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
           QC C  G  GQ C  C SG        G    C P      G  + + G C         
Sbjct: 554 QCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPA-----GTINSNLGYCQCKLHVEGP 608

Query: 441 ECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVMPETEEVVCN-NCPPGVTGARCELCAD 498
            C+ C + ++N D  +P  C  C CH   + S   E  +   + +C   V G  C+ C D
Sbjct: 609 TCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCED 668

Query: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
           GYF     E      CQ CQC  ++  + S  C   +G C +C  +  G  C + +  Y+
Sbjct: 669 GYFA---LEKSNYFGCQGCQC--DIGGALSSMCSGPSGVC-QCREHVVGKVCQRPENNYY 722



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 42/156 (26%), Positives = 63/156 (40%), Gaps = 23/156 (14%)

Query: 30  CNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCN 87
           C G S  C     ++   G       C  + +G  C +CK  ++   + +   C  C C+
Sbjct: 579 CQGSSSACDPAGTINSNLGY----CQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCH 634

Query: 88  SKGSLSARCD---NSGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDC 141
             G++S   +     G C CK  V G  CD C  G+  L  +   GC          C C
Sbjct: 635 KAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGC--------QGCQC 686

Query: 142 DPAG-IAGPCD--AGRCVCKPAVTGERCDRCRSGYY 174
           D  G ++  C   +G C C+  V G+ C R  + YY
Sbjct: 687 DIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYY 722



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 3/62 (4%)

Query: 139  CDCDPAGIAGP-C--DAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSAS 195
            C+C P G  GP C  + G+C C+P V G +C RC +G+Y      P  C +  C   +  
Sbjct: 1266 CECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQ 1325

Query: 196  CR 197
            CR
Sbjct: 1326 CR 1327



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 34/130 (26%), Positives = 45/130 (34%), Gaps = 33/130 (25%)

Query: 84  CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDP 143
           CN N+   L        RC C+    G  CDRC  G++         +Q      C+C  
Sbjct: 308 CNINNPEKLF-------RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCH- 359

Query: 144 AGIAGPC--------------------DAGRCV-CKPAVTGERCDRCRSGYYNLDG---G 179
            G A  C                      G C+ C+    G  C++C  GYY   G    
Sbjct: 360 -GHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418

Query: 180 NPEGCTQCFC 189
            P+GC  C C
Sbjct: 419 APDGCIPCSC 428



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 11/72 (15%)

Query: 135 LDSKCDC----DPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEG------C 184
           +  +C C    +   I  P    RC C+    GE CDRC +G YN     P        C
Sbjct: 295 IGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTG-YNQRRWRPAAWEQSHEC 353

Query: 185 TQCFCYGHSASC 196
             C C+GH+++C
Sbjct: 354 EACNCHGHASNC 365



 Score = 37.7 bits (86), Expect = 0.061
 Identities = 49/256 (19%), Positives = 103/256 (40%), Gaps = 40/256 (15%)

Query: 856  SRLQGVSDQSFQVEEAKRIKQKADSLS-------SLVTRHMDEFKRTQKNLGNWKEEAQQ 908
            S+LQG+S  +  +E+ + ++ +A  L        S ++ H  + +  ++ L +  +E + 
Sbjct: 1845 SQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFET 1904

Query: 909  LLQNGKSGREKSDQLLSRANLAKSRAQEA----------LSMGNA--TFYEVE------- 949
            L +  +    K+  L +  N A   A+E           + M N   T+ +         
Sbjct: 1905 LQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHMLNRIRTWQKTHQGENNGL 1964

Query: 950  --SILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRA 1007
              SI  +L E++ ++ + +A  +EA       + +   A+   Q+ ERALG+     +  
Sbjct: 1965 ANSIRDSLNEYEAKLSDLRARLQEA-------AAQAKQANGLNQENERALGAIQRQVKEI 2017

Query: 1008 KNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEF 1067
             +   +  +  +  +  +    L+ N+        +K    L + + E   EL  K  E 
Sbjct: 2018 NSLQSDFTKYLTTADSSL----LQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVREL 2073

Query: 1068 DTNMDAVQMVITEAQK 1083
              +     +V  EA+K
Sbjct: 2074 SRSAGKTSLV-EEAEK 2088


>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
          Length = 3333

 Score =  235 bits (600), Expect = 2e-61
 Identities = 274/1077 (25%), Positives = 442/1077 (41%), Gaps = 165/1077 (15%)

Query: 56   CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSA---RCD-NSGRCSCKPGVTGA 111
            C   T    CE C+   +       C  CNC+ +G++ A    CD +SG+C CKP +TG 
Sbjct: 1328 CPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGR 1387

Query: 112  RCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPCD--AGRCVCKPAVTGERCDR 168
            +CDRC  GF+   +             C+C+  G   G CD   G C+CK  V G  C+ 
Sbjct: 1388 QCDRCASGFYRFPEC----------VPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNV 1437

Query: 169  CRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPA 228
            CR G ++LD  N +GCT CFC+G +  C SS     HK  + F  D+ GW     +    
Sbjct: 1438 CREGSFHLDPANLKGCTSCFCFGVNNQCHSS-----HKRRTKF-VDMLGWHLETADRVDI 1491

Query: 229  KLQWSQRHQDVFSSAQRLDPVY----FVAPAKFLGNQQVSYG-----QSLSFDYRVDRGG 279
             + ++     + +  Q L        +VAP  +LG++  SYG     Q+ SF    D   
Sbjct: 1492 PVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVL 1551

Query: 280  RHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRL 339
                  DV L G  + I        +       + +    N   +++ +P +S  E   +
Sbjct: 1552 LEKKP-DVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAP-VSREELMTV 1609

Query: 340  LRNLTALRIRATY-GEYSTGYIDNVTLISARPV-SGAPAPWVEQCICPVGYKGQFCQDCA 397
            L  L  +RI+  Y  E     +  V L  A    SG  A  VE C CP  Y G  CQ C+
Sbjct: 1610 LSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCS 1669

Query: 398  SGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPDIE-CADCPIGFY-NDPH 454
             GY RD   L   G C+PCNC G    C   +G C +   N   E C  C  G+Y N  H
Sbjct: 1670 PGYYRDHKGLYT-GRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVH 1728

Query: 455  DPRSCKPCPCH--NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVR 512
               SC+ CPC   N F+   +    +V C+ C  G TG +CE CA GYFG+P    G   
Sbjct: 1729 G--SCRACPCPHTNSFATGCVVNGGDVRCS-CKAGYTGTQCERCAPGYFGNPQKFGG--- 1782

Query: 513  PCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRA 572
             CQPC CN+N      G+C  LTG C+                    +P   +PA++C  
Sbjct: 1783 SCQPCSCNSN---GQLGSCHPLTGDCIN------------------QEPKDSSPAEECDD 1821

Query: 573  C-NCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAF-SCPACYNQVKIQMDQFMQQLQRM 630
            C +C       +    +   + K    G +   G          Q K   +Q +     +
Sbjct: 1822 CDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAI 1881

Query: 631  EALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENS 690
                SK +G         LE  +    Q  + +   AQ++   +++L             
Sbjct: 1882 SNHGSKIEG---------LERELTDLNQEFETLQEKAQVNSRKAQTLN------------ 1920

Query: 691  YQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVG 750
                 +++    +  + L  + +N +R+ H L+ Q+  +  E     GN N+P+ D    
Sbjct: 1921 -----NNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGE-----GN-NVPSGD---- 1965

Query: 751  PNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRK-----ALHEGVGSGS 805
               F     EA R+         N  +  RE E   +++  L+ +       H+G  +G 
Sbjct: 1966 ---FSREWAEAQRMMRE--LRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGL 2020

Query: 806  GSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQS 865
             +   ++   L E   K   L  +L   A QA+ +A+   Q + R L ++ R Q     S
Sbjct: 2021 AN---SIRDSLNEYEAKLSDLRARLQEAAAQAK-QANGLNQENERALGAIQR-QVKEINS 2075

Query: 866  FQVEEAKRIKQKADSL--SSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQL 923
             Q +  K +     SL  +++  + M++ ++  + L     EA+Q         E SD++
Sbjct: 2076 LQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQ---------ELSDKV 2126

Query: 924  LSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVD--NRKAEAEEAMKRLSYISQ 981
                 L++S  + +L        E E   ++L+E   Q++   R A  +E ++       
Sbjct: 2127 ---RELSRSAGKTSL------VEEAEKHARSLQELAKQLEEIKRNASGDELVR------- 2170

Query: 982  KVSDASDKTQQAERALGSAAADAQRAKNGAGEALE--ISSEIEQEIGSLNLEANVTADGA 1039
               DA+   +    A+ +A   A RA + +  AL+  I  ++ ++  +L+  ++   + A
Sbjct: 2171 CAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEA 2230

Query: 1040 LAMEKGLASLKSEMREVEGELE--------RKELEFDTNMDAVQMVITEAQKVDTRA 1088
               +K    LK E+      L+        +KE+  DTN+  ++  +   Q+ D  A
Sbjct: 2231 KMTQK---KLKQEVSPALNNLQQTLNIVTVQKEV-IDTNLTTLRDGLHGIQRGDIDA 2283



 Score =  120 bits (302), Expect = 5e-27
 Identities = 69/201 (34%), Positives = 99/201 (49%), Gaps = 34/201 (16%)

Query: 17  PAARATSRR-EVCDCNGKSRQCIFDRELHRQTGN---------GFRCLNCNDNTDGIHCE 66
           PAA   S   E C+C+G +  C +D ++ RQ  +         G  C+NC  NT G++CE
Sbjct: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403

Query: 67  KCKNGFYRH-----RERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH 121
           +C  G+YR         D C+PC+C+ + +       SGRC CKP   G  C++C  G++
Sbjct: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCE-QGSGRCHCKPNFHGDNCEKCAIGYY 462

Query: 122 ML----------TDAGCTQDQRLLDSK-CDCDPAGIAGP-CDA-GRCVCKPAVTGERCDR 168
                            ++D    D K CDC+  G+    CDA GRC+C+P V G RCD 
Sbjct: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDT 522

Query: 169 CRSGYYNLDGGNPEGCTQCFC 189
           CRSG+Y+        C  C+C
Sbjct: 523 CRSGFYSF-----PICQACWC 538



 Score =  107 bits (268), Expect = 5e-23
 Identities = 56/140 (40%), Positives = 73/140 (52%), Gaps = 14/140 (10%)

Query: 52  RCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTG 110
           RCL C    +G  C+ C++GFY       C  C C++ GS    C + +G+C C+PGVTG
Sbjct: 508 RCL-CRPGVEGPRCDTCRSGFYSF---PICQACWCSALGSYQMPCSSVTGQCECRPGVTG 563

Query: 111 ARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCR 170
            RCDRCL G +               S   CDPAG     + G C CK  V G  C RC+
Sbjct: 564 QRCDRCLSGAYDFPHCQ--------GSSSACDPAGTINS-NLGYCQCKLHVEGPTCSRCK 614

Query: 171 SGYYNLDGGNPEGCTQCFCY 190
             Y+NLD  NP GC++C C+
Sbjct: 615 LLYWNLDKENPSGCSECKCH 634



 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 22/158 (13%)

Query: 22   TSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRC 81
            T R   C+CNG S QC        Q G+G  C+NC  NT G HCE+C+ G+Y +     C
Sbjct: 1681 TGRCVPCNCNGHSNQC--------QDGSGI-CVNCQHNTAGEHCERCQEGYYGNAVHGSC 1731

Query: 82   LPCNCNSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSK 138
              C C    S +  C  +G   RCSCK G TG +C+RC PG+      G  Q        
Sbjct: 1732 RACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF-----GNPQKFGGSCQP 1786

Query: 139  CDCDPAGIAGPCD--AGRCV---CKPAVTGERCDRCRS 171
            C C+  G  G C    G C+    K +   E CD C S
Sbjct: 1787 CSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 1824



 Score = 96.3 bits (238), Expect = 1e-19
 Identities = 80/276 (28%), Positives = 108/276 (39%), Gaps = 58/276 (21%)

Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPF---GTCIPCNCQGGGA---CDPDT------ 428
           +C C     G+ C  C +GY +   R   +     C  CNC G  +    DPD       
Sbjct: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQAS 377

Query: 429 ----------GDCYSGDEN-PDIECADCPIGFYND---PHD-PRSCKPCPC--HNGFSCS 471
                     G C +   N   + C  C  G+Y     P D P  C PC C   +   C 
Sbjct: 378 LNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGC- 436

Query: 472 VMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQ-----------CN 520
              E     C +C P   G  CE CA GY+  PF    P+ P                C+
Sbjct: 437 ---EQGSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCD 492

Query: 521 NNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGS 580
            N++      CD   GRCL C     G  CD C++G++  P+       C+AC C+ +GS
Sbjct: 493 CNLEGVLPEICD-AHGRCL-CRPGVEGPRCDTCRSGFYSFPI-------CQACWCSALGS 543

Query: 581 EPVGCRS-DGTCVCKPGFGGPNCEH---GAFSCPAC 612
             + C S  G C C+PG  G  C+    GA+  P C
Sbjct: 544 YQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHC 579



 Score = 94.0 bits (232), Expect = 7e-19
 Identities = 65/217 (29%), Positives = 87/217 (40%), Gaps = 40/217 (18%)

Query: 414  IPCNCQGGGA----CDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFS 469
            +PC C   GA    C P+ G C         +C  C  G Y  P     CKPC C     
Sbjct: 1264 LPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR----CKPCSCGRRL- 1318

Query: 470  CSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN-VDPSAS 528
            C  M       C  CPP     +CE+C    F        P+  C+ C C+      +A 
Sbjct: 1319 CEEMTGQ----CR-CPPRTVRPQCEVCETHSFS-----FHPMAGCEGCNCSRRGTIEAAM 1368

Query: 529  GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RS 587
              CDR +G+C +C     G  CD+C +G++  P       +C  CNCN  G+EP  C   
Sbjct: 1369 PECDRDSGQC-RCKPRITGRQCDRCASGFYRFP-------ECVPCNCNRDGTEPGVCDPG 1420

Query: 588  DGTCVCKPGFGGPN---CEHGAF--------SCPACY 613
             G C+CK    G     C  G+F         C +C+
Sbjct: 1421 TGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCF 1457



 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 62/197 (31%), Positives = 82/197 (41%), Gaps = 24/197 (12%)

Query: 381  QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
            QC C     G+ C  CA+G+         F  C PC+C G   C+  TG C         
Sbjct: 1284 QCPCQPNVIGRQCTRCATGHY-------GFPRCKPCSC-GRRLCEEMTGQCRCPPRTVRP 1335

Query: 441  ECADCPIGFYNDPHDPRSCKPCPC-HNGFSCSVMPETEEVVCN-NCPPGVTGARCELCAD 498
            +C  C    ++  H    C+ C C   G   + MPE +       C P +TG +C+ CA 
Sbjct: 1336 QCEVCETHSFSF-HPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCAS 1394

Query: 499  GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
            G++  P         C PC CN   D +  G CD  TG CL C  N  G  C+ C+ G F
Sbjct: 1395 GFYRFP--------ECVPCNCNR--DGTEPGVCDPGTGACL-CKENVEGTECNVCREGSF 1443

Query: 559  GDPLAPNPADKCRACNC 575
               L P     C +C C
Sbjct: 1444 --HLDPANLKGCTSCFC 1458



 Score = 87.4 bits (215), Expect = 7e-17
 Identities = 74/259 (28%), Positives = 99/259 (38%), Gaps = 76/259 (29%)

Query: 382 CI-CPVGYKGQFCQDCASGYKRDSARLGPFGT-------CIPCNC--QGGGACDPDTGDC 431
           CI C     G  C+ CA GY R      P+G        CIPC+C  +    C+  +G C
Sbjct: 390 CINCQHNTAGVNCEQCAKGYYR------PYGVPVDAPDGCIPCSCDPEHADGCEQGSGRC 443

Query: 432 YSGDENPDIECADCPIGFYNDP---------------HDP--RSCKPCPCHNGFSCSVMP 474
           +         C  C IG+YN P                DP     K C C+      V+P
Sbjct: 444 HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLE---GVLP 500

Query: 475 ETEEVVCNN-----CPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASG 529
           E    +C+      C PGV G RC+ C  G++  P         CQ C C      SA G
Sbjct: 501 E----ICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI--------CQACWC------SALG 542

Query: 530 N----CDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC 585
           +    C  +TG+C +C     G  CD+C +G +  P     +  C          +P G 
Sbjct: 543 SYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDFPHCQGSSSAC----------DPAGT 591

Query: 586 RSD--GTCVCKPGFGGPNC 602
            +   G C CK    GP C
Sbjct: 592 INSNLGYCQCKLHVEGPTC 610



 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 52/171 (30%), Positives = 73/171 (42%), Gaps = 22/171 (12%)

Query: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQC 519
           C C+       +   E++    C     G  C+ C  GY    +          C+ C C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358

Query: 520 NNNV-----DP-----SASGNCDRL---TGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
           + +      DP      AS N   +    G C+ C HNTAG+ C+QC  GY+     P  
Sbjct: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418

Query: 567 A-DKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
           A D C  C+C+P  ++  GC +  G C CKP F G NCE    G ++ P C
Sbjct: 419 APDGCIPCSCDPEHAD--GCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFC 467



 Score = 74.3 bits (181), Expect = 6e-13
 Identities = 70/246 (28%), Positives = 92/246 (37%), Gaps = 46/246 (18%)

Query: 381 QCICPVGYKGQFCQDCASGYKRDS--ARLGPFGTCIP------------CNCQGGGACDP 426
           +C C   + G  C+ CA GY       R+  F    P            C+C   G   P
Sbjct: 442 RCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVL-P 500

Query: 427 DTGD------CYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV 480
           +  D      C  G E P   C  C  GFY+ P     C+ C C +      MP +    
Sbjct: 501 EICDAHGRCLCRPGVEGP--RCDTCRSGFYSFP----ICQACWC-SALGSYQMPCSSVTG 553

Query: 481 CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK 540
              C PGVTG RC+ C  G +  P  + G    C P           +G  +   G C +
Sbjct: 554 QCECRPGVTGQRCDRCLSGAYDFPHCQ-GSSSACDP-----------AGTINSNLGYC-Q 600

Query: 541 CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG--SEPVGCR-SDGTCVCKPGF 597
           C  +  G  C +CK  Y+   L       C  C C+  G  S    CR  DG C CK   
Sbjct: 601 CKLHVEGPTCSRCKLLYWN--LDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHV 658

Query: 598 GGPNCE 603
           GG +C+
Sbjct: 659 GGDSCD 664



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 52/177 (29%), Positives = 73/177 (41%), Gaps = 41/177 (23%)

Query: 447  IGFYNDPHDPRSCKPCPCH----NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFG 502
            + FY+     +   PC CH     G  CS  PE  +  C    P V G +C  CA G++G
Sbjct: 1256 VAFYH-----KGALPCECHPTGATGPHCS--PEGGQCPCQ---PNVIGRQCTRCATGHYG 1305

Query: 503  DPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPL 562
             P         C+PC C   +       C+ +TG+C +C   T    C+ C+   F    
Sbjct: 1306 FP--------RCKPCSCGRRL-------CEEMTGQC-RCPPRTVRPQCEVCETHSF---- 1345

Query: 563  APNPADKCRACNCNPMG----SEPVGCRSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
            + +P   C  CNC+  G    + P   R  G C CKP   G  C+    G +  P C
Sbjct: 1346 SFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPEC 1402



 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 50/180 (27%), Positives = 71/180 (39%), Gaps = 13/180 (7%)

Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
           QC C  G  GQ C  C SG        G    C P      G  + + G C         
Sbjct: 554 QCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPA-----GTINSNLGYCQCKLHVEGP 608

Query: 441 ECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVMPETEEVVCN-NCPPGVTGARCELCAD 498
            C+ C + ++N D  +P  C  C CH   + S   E  +   + +C   V G  C+ C D
Sbjct: 609 TCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCED 668

Query: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
           GYF     E      CQ CQC  ++  + S  C   +G C +C  +  G  C + +  Y+
Sbjct: 669 GYFA---LEKSNYFGCQGCQC--DIGGALSSMCSGPSGVC-QCREHVVGKVCQRPENNYY 722



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 42/156 (26%), Positives = 63/156 (40%), Gaps = 23/156 (14%)

Query: 30  CNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCN 87
           C G S  C     ++   G       C  + +G  C +CK  ++   + +   C  C C+
Sbjct: 579 CQGSSSACDPAGTINSNLGY----CQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCH 634

Query: 88  SKGSLSARCD---NSGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDC 141
             G++S   +     G C CK  V G  CD C  G+  L  +   GC          C C
Sbjct: 635 KAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGC--------QGCQC 686

Query: 142 DPAG-IAGPCD--AGRCVCKPAVTGERCDRCRSGYY 174
           D  G ++  C   +G C C+  V G+ C R  + YY
Sbjct: 687 DIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYY 722



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 3/62 (4%)

Query: 139  CDCDPAGIAGP-C--DAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSAS 195
            C+C P G  GP C  + G+C C+P V G +C RC +G+Y      P  C +  C   +  
Sbjct: 1266 CECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQ 1325

Query: 196  CR 197
            CR
Sbjct: 1326 CR 1327



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 34/130 (26%), Positives = 45/130 (34%), Gaps = 33/130 (25%)

Query: 84  CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDP 143
           CN N+   L        RC C+    G  CDRC  G++         +Q      C+C  
Sbjct: 308 CNINNPEKLF-------RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCH- 359

Query: 144 AGIAGPC--------------------DAGRCV-CKPAVTGERCDRCRSGYYNLDG---G 179
            G A  C                      G C+ C+    G  C++C  GYY   G    
Sbjct: 360 -GHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418

Query: 180 NPEGCTQCFC 189
            P+GC  C C
Sbjct: 419 APDGCIPCSC 428



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 11/72 (15%)

Query: 135 LDSKCDC----DPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEG------C 184
           +  +C C    +   I  P    RC C+    GE CDRC +G YN     P        C
Sbjct: 295 IGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTG-YNQRRWRPAAWEQSHEC 353

Query: 185 TQCFCYGHSASC 196
             C C+GH+++C
Sbjct: 354 EACNCHGHASNC 365


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score =  225 bits (573), Expect = 2e-58
 Identities = 174/599 (29%), Positives = 254/599 (42%), Gaps = 86/599 (14%)

Query: 28   CDCNGKSRQC--IFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRER---DRCL 82
            C+CNG +  C  ++             CLNC  NT+G  C KCK GF+    +     C 
Sbjct: 764  CNCNGHASSCDPVYGH-----------CLNCQHNTEGPQCNKCKAGFFGDAMKATATSCR 812

Query: 83   PCNC---NSKGSLSARC----DNSGRC-SCKPGVTGARCDRCLPGFHMLTDAGCTQDQRL 134
            PC C   ++    S  C    D    C +C PG TG RC+ C PG+         + + +
Sbjct: 813  PCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPV 872

Query: 135  LDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSA 194
                  CD  G  G      C CK  V G  C+ C  G ++L   NP+GC +CFC G S 
Sbjct: 873  NQEIVRCDERGSMGTSGEA-CRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCMGVSR 931

Query: 195  SCRSSA--------------EYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVF 240
             C SS+               +S+    ST H   +G  +     +P +L +S  H+ + 
Sbjct: 932  HCTSSSWSRAQLHGASEEPGHFSLTNAAST-HTTNEGIFSP----TPGELGFSSFHRLLS 986

Query: 241  SSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHD---VILEGAGLRIT 297
                   P ++  P++FLG++  SYG  L F             H    V+L+G  + + 
Sbjct: 987  G------PYFWSLPSRFLGDKVTSYGGELRFTVTQRSQPGSTPLHGQPLVVLQGNNIILE 1040

Query: 298  APLMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRL-LRNLTALRIRATYGEY- 355
              +    +    G   T+     E        Q +  E+  + L  +  L IRA+Y +  
Sbjct: 1041 HHV---AQEPSPGQPSTFIVPFREQAWQRPDGQPATREHLLMALAGIDTLLIRASYAQQP 1097

Query: 356  STGYIDNVTLISARPVSGA--PAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTC 413
            +   +  +++  A P      PA  VEQC CP GY+G  CQDC +GY R  + L   GTC
Sbjct: 1098 AESRVSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGL-YLGTC 1156

Query: 414  IPCNCQG-GGACDPDTGDCYSGDENPD-IECADCPIGFYNDPH--DPRSCKPCPCHNGFS 469
              C+C G   AC+P+TG C     + +   C  C  G+Y D     P+ C+ CPC+   +
Sbjct: 1157 ERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPA 1216

Query: 470  CSVMPET------EEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQ-------P 516
                  T          C+ C PG +G  CE CA GY+G+P       +PCQ       P
Sbjct: 1217 AGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNP----SQGQPCQRDSQVPGP 1272

Query: 517  CQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNC 575
              CN +   S S  CD   G+C +C     G+ C  C+  +F   L+ +  D C  C C
Sbjct: 1273 IGCNCDPQGSVSSQCD-AAGQC-QCKAQVEGLTCSHCRPHHF--HLSASNPDGCLPCFC 1327



 Score =  206 bits (524), Expect = 1e-52
 Identities = 170/529 (32%), Positives = 233/529 (44%), Gaps = 56/529 (10%)

Query: 26   EVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR---CL 82
            E C C+G S  C        +TG    C  C  +T+G  CE+C+ G+Y   +R     C 
Sbjct: 1157 ERCSCHGHSEAC------EPETG---ACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQ 1207

Query: 83   PCNCN---SKGSLSARC----DNSGRC-SCKPGVTGARCDRCLPGFHMLTDAG--CTQDQ 132
             C C    + G  +  C    D    C +C PG +G  C+RC PG++     G  C +D 
Sbjct: 1208 LCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDS 1267

Query: 133  RLLDS-KCDCDPAG-IAGPCDA-GRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
            ++     C+CDP G ++  CDA G+C CK  V G  C  CR  +++L   NP+GC  CFC
Sbjct: 1268 QVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327

Query: 190  YGHSASCRSSAEYSVHKITSTFHQ-DVDGWKAV--QRN----GSPAKLQWSQRHQDVFSS 242
             G +  C SSA Y+ H I++ F   D  G+  V  QRN    G        +  Q  F +
Sbjct: 1328 MGITQQCASSA-YTRHLISTHFAPGDFQGFALVNPQRNSRLTGEFTVEPVPEGAQLSFGN 1386

Query: 243  AQRL--DPVYFVAPAKFLGNQQVSYGQSLSF--DYRVDRGGRHPSAHDVILEGAGLRITA 298
              +L  +  Y+  P  + G++  +YG  L +   Y     G   S  DV + G  + + A
Sbjct: 1387 FAQLGHESFYWQLPETYQGDKVAAYGGKLRYTLSYTAGPQGSPLSDPDVQITGNNIMLVA 1446

Query: 299  PLMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRL-LRNLTALRIRATYGEYS- 356
                    L     ++Y     E        Q +  E+  + L +L  L IRAT+     
Sbjct: 1447 S----QPALQGPERRSYEIMFREEFWRRPDGQPATREHLLMALADLDELLIRATFSSVPL 1502

Query: 357  TGYIDNVTLISARP-VSGAP-APWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCI 414
               I  V+L  A+P  S  P A  VE+C CP GY G  CQDCA GY R  + L   G C 
Sbjct: 1503 AASISAVSLEVAQPGPSNRPRALEVEECRCPPGYIGLSCQDCAPGYTRTGSGL-YLGHCE 1561

Query: 415  PCNCQG-GGACDPDTGDCYSGDENPDIE-CADCPIGFYND--PHDPRSCKPCPCHNGFSC 470
             C C G    C P+TG C     N   E C  C  G+Y D     P  C+PC C      
Sbjct: 1562 LCECNGHSDLCHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPE 1621

Query: 471  SVMPETEEVV------CNNCPPGVTGARCELCADGYFGDPFGEHGPVRP 513
            ++   T E +      C  C PG TG  CE C  GY G+P  + G   P
Sbjct: 1622 NMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLP 1670



 Score =  159 bits (401), Expect = 2e-38
 Identities = 133/441 (30%), Positives = 195/441 (44%), Gaps = 53/441 (12%)

Query: 169 CRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQ-----R 223
           C  G++ L+  +   C  CFC+G ++ C+S+  +   +I   F Q  D +K V      +
Sbjct: 505 CPDGHFYLE--HSAACLPCFCFGITSVCQSTRRFR-DQIRLRFDQP-DDFKGVNVTMPAQ 560

Query: 224 NGSPAKLQWSQRHQDVFSSAQRLD--------PVYFVAPAKFLGNQQVSYGQSLSFD--Y 273
            G+P       +        Q +D          ++  P +FLGN+  SYG SL ++  Y
Sbjct: 561 PGTPPLSSTQLQIDPSLHEFQLVDLSRRFLVHDSFWALPEQFLGNKVDSYGGSLRYNVRY 620

Query: 274 RVDRGGRHPSAH-DVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLS 332
            + RG   P    DV+L GAG R+ +       T P  L +       EH  +     + 
Sbjct: 621 ELARGMLEPVQRPDVVLMGAGYRLLS--RGHTPTQPGALNQRQVQFSEEHWVHESGRPVQ 678

Query: 333 YFEYRRLLRNLTALRIRATYGEY--STGYID---NVTLISARPVSGAPAPWVEQCICPVG 387
             E  ++L++L A+ I+  Y     S G  D   + T+  A   S   A  VE+C CP+G
Sbjct: 679 RAELLQVLQSLEAVLIQTVYNTKMASVGLSDIAMDTTVTHA--TSHGRAHSVEECRCPIG 736

Query: 388 YKGQFCQDCASGYKRDSARLGPF-GTCIPCNCQG-GGACDPDTGDCYSGDENPD-IECAD 444
           Y G  C+ C + + R     GP+ GTC  CNC G   +CDP  G C +   N +  +C  
Sbjct: 737 YSGLSCESCDAHFTRVPG--GPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGPQCNK 794

Query: 445 CPIGFYNDPHDPR--SCKPCPC-----HNGFSCSVMPETE-EVVCNNCPPGVTGARCELC 496
           C  GF+ D       SC+PCPC        FS +   +T+ +  C+ C PG TG RCE C
Sbjct: 795 CKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESC 854

Query: 497 ADGYFGDPFGEHGPVRPC--QPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCK 554
           A GY G+P    G  RP   +  +C+       SG   R       C +N  G  C++C 
Sbjct: 855 APGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACR-------CKNNVVGRLCNECA 907

Query: 555 AGYFGDPLAPNPADKCRACNC 575
            G F   L+    D C  C C
Sbjct: 908 DGSF--HLSTRNPDGCLKCFC 926



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 51/138 (36%), Positives = 64/138 (46%), Gaps = 16/138 (11%)

Query: 474  PETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDR 533
            P   EV    CPPG  G  C+ CA GY     G +  +  C+ C+CN + D      C  
Sbjct: 1522 PRALEVEECRCPPGYIGLSCQDCAPGYTRTGSGLY--LGHCELCECNGHSDL-----CHP 1574

Query: 534  LTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNC---NPMGSEPVGCRSDGT 590
             TG C +C HN AG +C+ C  GY+GD  A  P D C+ C C   NP       C S G 
Sbjct: 1575 ETGACSQCQHNAAGEFCELCAPGYYGDATAGTPED-CQPCACPLTNPENMFSRTCESLGA 1633

Query: 591  -----CVCKPGFGGPNCE 603
                   C+PG+ G  CE
Sbjct: 1634 GGYRCTACEPGYTGQYCE 1651



 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 52/144 (36%), Positives = 68/144 (47%), Gaps = 20/144 (13%)

Query: 484 CPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIH 543
           CP G +G  CE C   +   P G +  +  C  C CN +     + +CD + G CL C H
Sbjct: 733 CPIGYSGLSCESCDAHFTRVPGGPY--LGTCSGCNCNGH-----ASSCDPVYGHCLNCQH 785

Query: 544 NTAGIYCDQCKAGYFGDPLAPNPADKCRACNC-----NPMGSEPVGCRSDG--TC-VCKP 595
           NT G  C++CKAG+FGD +    A  CR C C     +   S+     +DG  TC  C P
Sbjct: 786 NTEGPQCNKCKAGFFGDAMKAT-ATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAP 844

Query: 596 GFGGPNCEHGAFSCPACYNQVKIQ 619
           G+ G  CE    SC   Y    IQ
Sbjct: 845 GYTGRRCE----SCAPGYEGNPIQ 864



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 47/140 (33%), Positives = 64/140 (45%), Gaps = 22/140 (15%)

Query: 478  EVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGR 537
            EV   +CPPG  G  C+ C  GY   P G +  +  C+ C C+ +     S  C+  TG 
Sbjct: 1122 EVEQCSCPPGYRGPSCQDCDTGYTRTPSGLY--LGTCERCSCHGH-----SEACEPETGA 1174

Query: 538  CLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTC------ 591
            C  C H+T G  C+QC+ GY+GD     P D C+ C C     +P   ++  TC      
Sbjct: 1175 CQGCQHHTEGPRCEQCQPGYYGDAQRGTPQD-CQLCPCY---GDPAAGQAAHTCFLDTDG 1230

Query: 592  -----VCKPGFGGPNCEHGA 606
                  C PG  G +CE  A
Sbjct: 1231 HPTCDACSPGHSGRHCERCA 1250



 Score = 35.8 bits (81), Expect = 0.23
 Identities = 26/95 (27%), Positives = 37/95 (38%), Gaps = 18/95 (18%)

Query: 458  SCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPC 517
            +C+  PC NG  C    E+   VC  CP G TG+RC             EH     C P 
Sbjct: 3847 TCRDRPCQNGGQCHDS-ESSSYVCV-CPAGFTGSRC-------------EHSQALHCHPE 3891

Query: 518  QCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQ 552
             C  +   +   N     G   +C    +G+ C++
Sbjct: 3892 ACGPD---ATCVNRPDGRGYTCRCHLGRSGLRCEE 3923



 Score = 34.7 bits (78), Expect = 0.52
 Identities = 15/43 (34%), Positives = 23/43 (53%), Gaps = 1/43 (2%)

Query: 155 CVCKPAVTGERCDRCRSGYYNLDGGNPEG-CTQCFCYGHSASC 196
           C C    +G  C+ C + +  + GG   G C+ C C GH++SC
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSC 773



 Score = 33.9 bits (76), Expect = 0.88
 Identities = 28/119 (23%), Positives = 44/119 (36%), Gaps = 21/119 (17%)

Query: 488  VTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAG 547
            V G R +L          G+     PC+   C +      +G  +       +C+     
Sbjct: 4082 VNGKRLDLTYSFLGSQGIGQCYDSSPCERQPCQHGATCMPAGEYE------FQCL----- 4130

Query: 548  IYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGA 606
                 C+ G+ GD L  +  + C+       G    G R    C+C PGF GP C+ G+
Sbjct: 4131 -----CRDGFKGD-LCEHEENPCQLREPCLHGGTCQGTR----CLCLPGFSGPRCQQGS 4179



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 24/86 (27%), Positives = 28/86 (32%), Gaps = 13/86 (15%)

Query: 412  TCIPCNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYN---DPHDPRSCKPCPCHNGF 468
            TC    CQ GG C       Y            CP GF     +      C P  C    
Sbjct: 3847 TCRDRPCQNGGQCHDSESSSY---------VCVCPAGFTGSRCEHSQALHCHPEACGPDA 3897

Query: 469  SCSVMPETEEVVCNNCPPGVTGARCE 494
            +C   P+     C  C  G +G RCE
Sbjct: 3898 TCVNRPDGRGYTC-RCHLGRSGLRCE 3922



 Score = 30.4 bits (67), Expect = 9.7
 Identities = 23/80 (28%), Positives = 33/80 (41%), Gaps = 9/80 (11%)

Query: 95   RCDNSGRCSCKPGVTGARCDRCLPG----FHMLTDAGCTQDQ-RLLDSKCDC-DPAGIAG 148
            +C +S  C  +P   GA C   +P     F  L   G   D     ++ C   +P    G
Sbjct: 4101 QCYDSSPCERQPCQHGATC---MPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCLHGG 4157

Query: 149  PCDAGRCVCKPAVTGERCDR 168
             C   RC+C P  +G RC +
Sbjct: 4158 TCQGTRCLCLPGFSGPRCQQ 4177


>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
          Length = 1786

 Score =  167 bits (424), Expect = 4e-41
 Identities = 94/250 (37%), Positives = 124/250 (49%), Gaps = 35/250 (14%)

Query: 377  PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-G 434
            P   QC C  G   + C  C  G+         F +C PC C G    CDP TG+C +  
Sbjct: 835  PVTGQCHCFQGVYARQCDRCLPGH-------WGFPSCQPCQCNGHADDCDPVTGECLNCQ 887

Query: 435  DENPDIECADCPIGFYNDP--HDPRSCKPCPCHNG--------FSCSVMPETEEVVCNNC 484
            D      C  C  G+Y DP       C+PCPC +G         SC   P T ++ C  C
Sbjct: 888  DYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACV-C 946

Query: 485  PPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHN 544
             PG  G+RC+ CA GYFG+P    G    CQPCQC+NN+D +    CD+ TGRCLKC+++
Sbjct: 947  DPGYIGSRCDDCASGYFGNPSEVGGS---CQPCQCHNNIDTTDPEACDKETGRCLKCLYH 1003

Query: 545  TAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC--------RSDGTCVCKPG 596
            T G +C  C+ GY+GD L  +    CR C CN +G+    C        ++ G C+C P 
Sbjct: 1004 TEGEHCQFCRFGYYGDALQQD----CRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPN 1059

Query: 597  FGGPNCEHGA 606
              G NC+  A
Sbjct: 1060 VIGQNCDRCA 1069



 Score =  159 bits (401), Expect = 2e-38
 Identities = 184/810 (22%), Positives = 310/810 (38%), Gaps = 113/810 (13%)

Query: 382  CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG------GACDPDTGDCYSGD 435
            C+C  GY G  C DCASGY  + + +G  G+C PC C          ACD +TG C    
Sbjct: 944  CVCDPGYIGSRCDDCASGYFGNPSEVG--GSCQPCQCHNNIDTTDPEACDKETGRCLKCL 1001

Query: 436  ENPDIE-CADCPIGFYNDPHDPRSCKPCPCH---------NGFSCSVMPETEEVVCNNCP 485
             + + E C  C  G+Y D    + C+ C C+         NG  C     T + +C    
Sbjct: 1002 YHTEGEHCQFCRFGYYGDALQ-QDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCL--- 1057

Query: 486  PGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNT 545
            P V G  C+ CA   +    G       C PC CN     S   +C+  TG+C +C+   
Sbjct: 1058 PNVIGQNCDRCAPNTWQLASGTG-----CDPCNCN--AAHSFGPSCNEFTGQC-QCMPGF 1109

Query: 546  AGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCE- 603
             G  C +C+  ++GDP       +CRAC+C+P G E   C +S G CVC  G  GP C+ 
Sbjct: 1110 GGRTCSECQELFWGDPDV-----ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDK 1164

Query: 604  -----HGAF-SCPACYNQVKIQMDQFMQQLQRMEALISKAQG--GDGVV-PDTELEGRMQ 654
                  G F  C  C+    +      +   R    + KA+     GV+ P  E    ++
Sbjct: 1165 CTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRFLEKAKALKISGVIGPYRETVDSVE 1224

Query: 655  QAEQALQDILRDAQISEGASR--------------------SLGLQLAKVRSQENSYQSR 694
            +    ++DIL  +  +E                         + ++L+   SQ NS    
Sbjct: 1225 RKVSEIKDILAQSPAAEPLKNIGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKE 1284

Query: 695  LDDLKMTVE----RVRALGSQYQ----NRVRDTHRLITQ-MQLSLAESEASLGNTNIPAS 745
            LD L+   E     V+ L  Q +    + +R     IT+  Q+SL   E    +T  P S
Sbjct: 1285 LDSLQTEAESLDNTVKELAEQLEFIKNSDIRGALDSITKYFQMSLEAEERVNASTTEPNS 1344

Query: 746  D--------------HYVGPNGFKSLAQEATRLAES--------HVESASNMEQLTRETE 783
                                + FK   +E  RL +          + +A+ M   T    
Sbjct: 1345 TVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDELAGKLQSLDLSAAAEMTCGTPPGA 1404

Query: 784  DYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQ----------QLTRE 833
              S+           EG     G   G +V       +K   L Q          QL++ 
Sbjct: 1405 SCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVEQLSKM 1464

Query: 834  ATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFK 893
             ++A++ AD + Q +  +L   +  +   D+S   EE + + ++  +  +  +  +D  +
Sbjct: 1465 VSEAKLRADEAKQSAEDILLKTNATKEKMDKS--NEELRNLIKQIRNFLTQDSADLDSIE 1522

Query: 894  RTQKNLGNWK-EEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESIL 952
                 +   +     Q LQN      +  + LS+  +    +   ++       E +   
Sbjct: 1523 AVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRAS 1582

Query: 953  KNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAG 1012
            K+  +  +  D  K   EEA K      + +  A +  Q  +  L S  ++   ++    
Sbjct: 1583 KSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLF 1642

Query: 1013 EALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMD 1072
             A +  SE+E+ +  L  +A   +  A  +EK + ++K    +V+  L+    E D    
Sbjct: 1643 NASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDVKKTLDG---ELDEKYK 1699

Query: 1073 AVQMVITEAQKVDTRAKNAGVTIQDTLNTL 1102
             V+ +I +  +    A+     +Q+   TL
Sbjct: 1700 KVENLIAKKTEESADARRKAEMLQNEAKTL 1729



 Score =  115 bits (288), Expect = 2e-25
 Identities = 73/212 (34%), Positives = 92/212 (43%), Gaps = 30/212 (14%)

Query: 404 SARLGPFGTCIPCNCQGG--GACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKP 461
           SA L   G    C+ QG     CDP+ G C          C  C  G +     P  CKP
Sbjct: 763 SALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFG--FGPSGCKP 820

Query: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNN 521
           C CH   S +         C +C  GV   +C+ C  G++G P         CQPCQCN 
Sbjct: 821 CECHLQGSVNAFCNPVTGQC-HCFQGVYARQCDRCLPGHWGFP--------SCQPCQCNG 871

Query: 522 NVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581
           + D     +CD +TG CL C   T G  C++C AGY+GDP+     D CR C C P G +
Sbjct: 872 HAD-----DCDPVTGECLNCQDYTMGHNCERCLAGYYGDPII-GSGDHCRPCPC-PDGPD 924

Query: 582 -----PVGCRSDG-----TCVCKPGFGGPNCE 603
                   C  D       CVC PG+ G  C+
Sbjct: 925 SGRQFARSCYQDPVTLQLACVCDPGYIGSRCD 956



 Score =  114 bits (284), Expect = 7e-25
 Identities = 81/234 (34%), Positives = 104/234 (44%), Gaps = 50/234 (21%)

Query: 6   LGCCLCFSLL--LPAARATSRR----EVCDCNGKSRQCIFDRELHRQTGN--GFRCLNCN 57
           L C LC      LP   A  R     + C+CN  S  C FD  ++  TGN  G  C +C 
Sbjct: 307 LNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQ 366

Query: 58  DNTDGIHCEKCKNGFYRHRERDR-----CLPCNCNSKGSLSAR-CDN---------SGRC 102
            NT G +CE+CK  +Y+H ERD      C  C C+  GS +   CD+         +G+C
Sbjct: 367 HNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQC 426

Query: 103 SCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDCDPAGI---AGPCDA--GR 154
            CK  V G  CD C  GF+ L+     GC          C C+P G      PCD+  G 
Sbjct: 427 RCKLNVEGEHCDVCKEGFYDLSSEDPFGC--------KSCACNPLGTIPGGNPCDSETGH 478

Query: 155 CVCKPAVTGERCDRCRSGYY----NLDGGNPEGC-------TQCFCYGHSASCR 197
           C CK  VTG+ CD+C   ++    +LDG  P  C         CF      SCR
Sbjct: 479 CYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCR 532



 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 73/231 (31%), Positives = 102/231 (44%), Gaps = 41/231 (17%)

Query: 8    CCLC-FSLLLPAARATSRREVCD--------CNGKSRQCIFDRELHRQTGNGFRCLNCND 58
            C  C F     A +   R+ VC+        CNG   QC       + TG   +CL C  
Sbjct: 1009 CQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQC------DKATG---QCL-CLP 1058

Query: 59   NTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCL 117
            N  G +C++C    ++      C PCNCN+  S    C+  +G+C C PG  G  C  C 
Sbjct: 1059 NVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQ 1118

Query: 118  PGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYY 174
              F    D  C          CDCDP GI  P CD   G+CVC   V G RCD+C  GY 
Sbjct: 1119 ELFWGDPDVECRA--------CDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGY- 1169

Query: 175  NLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNG 225
               G  P+ CT C        C +  +  + ++T+  H+ ++  KA++ +G
Sbjct: 1170 --SGVFPD-CTPCH------QCFALWDVIIAELTNRTHRFLEKAKALKISG 1211



 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 56/160 (35%), Positives = 74/160 (46%), Gaps = 18/160 (11%)

Query: 25  REVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERD--RCL 82
           R  CD  G   + I D      TG       C  N +G HC+ CK GFY     D   C 
Sbjct: 397 RCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCK 456

Query: 83  PCNCNSKGSLSA--RCDN-SGRCSCKPGVTGARCDRCLPGFHMLTD--AGCTQDQRLLDS 137
            C CN  G++     CD+ +G C CK  VTG  CD+CLP    L++   GC         
Sbjct: 457 SCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGC--------R 508

Query: 138 KCDCDPAG-IAGPC--DAGRCVCKPAVTGERCDRCRSGYY 174
            CDCD  G +   C  ++G+C C+P + G +C+    GYY
Sbjct: 509 PCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548



 Score = 88.2 bits (217), Expect = 4e-17
 Identities = 59/196 (30%), Positives = 86/196 (43%), Gaps = 40/196 (20%)

Query: 28  CDCNGKSRQCI----FDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFY-------RHR 76
           C C G + +C     F+ E+         C+ C  NT G++CE C + ++         R
Sbjct: 271 CFCYGHASECAPVDGFNEEVEGMVHG--HCM-CRHNTKGLNCELCMDFYHDLPWRPAEGR 327

Query: 77  ERDRCLPCNCNSKGSLSARCD----------NSGRCS-CKPGVTGARCDRCLPGFHMLTD 125
             + C  CNCN   S+S   D          + G C  C+    G  C++C P ++   +
Sbjct: 328 NSNACKKCNCNEH-SISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPE 386

Query: 126 AGCTQDQRLLDSKCDCDPAGIA--GPCD----------AGRCVCKPAVTGERCDRCRSGY 173
               +D    + +C CDPAG    G CD          AG+C CK  V GE CD C+ G+
Sbjct: 387 RDI-RDPNFCE-RCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGF 444

Query: 174 YNLDGGNPEGCTQCFC 189
           Y+L   +P GC  C C
Sbjct: 445 YDLSSEDPFGCKSCAC 460



 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 69/260 (26%), Positives = 93/260 (35%), Gaps = 56/260 (21%)

Query: 382 CICPVGYKGQFCQDCASGYKRDSARLGP---FGTCIPCNCQ------------------- 419
           C+C    KG  C+ C   Y     R         C  CNC                    
Sbjct: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357

Query: 420 GGGACDPDTGDCYSGDENPDIECADCPIGFYNDPH----DPRSCKPCPC------HNGFS 469
            GG CD    DC       +  C  C   +Y  P     DP  C+ C C      + G  
Sbjct: 358 SGGVCD----DCQHNTMGRN--CEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGIC 411

Query: 470 CSVMPETEEVVCNNC--PPGVTGARCELCADGYFG----DPFGEHGPVRPCQPCQCNNNV 523
            S    +  ++   C     V G  C++C +G++     DPFG       C+ C CN   
Sbjct: 412 DSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFG-------CKSCACNPLG 464

Query: 524 DPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPV 583
                  CD  TG C  C     G +CDQC   ++G     N  D CR C+C+  G+   
Sbjct: 465 TIPGGNPCDSETGHCY-CKRLVTGQHCDQCLPEHWG---LSNDLDGCRPCDCDLGGALNN 520

Query: 584 GCRSD-GTCVCKPGFGGPNC 602
            C ++ G C C+P   G  C
Sbjct: 521 SCFAESGQCSCRPHMIGRQC 540



 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 63/204 (30%), Positives = 89/204 (43%), Gaps = 37/204 (18%)

Query: 429 GDCYSGDENPDIECADCPIGFYND----PHDPRS---CKPCPCHNG-----FSCSVMPET 476
           G C        + C  C + FY+D    P + R+   CK C C+       F  +V   T
Sbjct: 296 GHCMCRHNTKGLNCELC-MDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354

Query: 477 EEV---VCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGN--- 530
             V   VC++C     G  CE C   Y+  P  +      C+ C C    DP+ S N   
Sbjct: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTC----DPAGSQNEGI 410

Query: 531 CDRLT--------GRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEP 582
           CD  T        G+C +C  N  G +CD CK G++   L+      C++C CNP+G+ P
Sbjct: 411 CDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFY--DLSSEDPFGCKSCACNPLGTIP 467

Query: 583 VG--CRSD-GTCVCKPGFGGPNCE 603
            G  C S+ G C CK    G +C+
Sbjct: 468 GGNPCDSETGHCYCKRLVTGQHCD 491



 Score = 80.5 bits (197), Expect = 8e-15
 Identities = 42/119 (35%), Positives = 57/119 (47%), Gaps = 17/119 (14%)

Query: 82  LPCNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCD 140
           L C C+ +GSLS+ CD N G+C C+P V G  C+RC PG      +GC          C+
Sbjct: 771 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGC--------KPCE 822

Query: 141 CDPAG-IAGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASC 196
           C   G +   C+   G+C C   V   +CDRC  G++         C  C C GH+  C
Sbjct: 823 CHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGF-----PSCQPCQCNGHADDC 876



 Score = 77.4 bits (189), Expect = 7e-14
 Identities = 49/144 (34%), Positives = 67/144 (46%), Gaps = 15/144 (10%)

Query: 49  NGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPG 107
           NG +C  C  N  G  C +C  G +       C PC C+ +GS++A C+  +G+C C  G
Sbjct: 788 NGGQC-QCRPNVVGRTCNRCAPGTFGFGPSG-CKPCECHLQGSVNAFCNPVTGQCHCFQG 845

Query: 108 VTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCV-CKPAVTGERC 166
           V   +CDRCLPG          Q     D   DCDP         G C+ C+    G  C
Sbjct: 846 VYARQCDRCLPGHWGFPSCQPCQCNGHAD---DCDPV-------TGECLNCQDYTMGHNC 895

Query: 167 DRCRSGYY-NLDGGNPEGCTQCFC 189
           +RC +GYY +   G+ + C  C C
Sbjct: 896 ERCLAGYYGDPIIGSGDHCRPCPC 919



 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 63/208 (30%), Positives = 80/208 (38%), Gaps = 40/208 (19%)

Query: 7    GCCLCFSLL--------LPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCND 58
            G C CF  +        LP        + C CNG +  C         TG    CLNC D
Sbjct: 838  GQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDC------DPVTGE---CLNCQD 888

Query: 59   NTDGIHCEKCKNGFYRH---RERDRCLPCNC----NSKGSLSARCDNSG-----RCSCKP 106
             T G +CE+C  G+Y        D C PC C    +S    +  C          C C P
Sbjct: 889  YTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDP 948

Query: 107  GVTGARCDRCLPGF--HMLTDAGCTQDQRLLDSKCDCDPAGIAGPCD--AGRCV-CKPAV 161
            G  G+RCD C  G+  +     G  Q  +  ++    DP      CD   GRC+ C    
Sbjct: 949  GYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEA----CDKETGRCLKCLYHT 1004

Query: 162  TGERCDRCRSGYYNLDGGNPEGCTQCFC 189
             GE C  CR GYY       + C +C C
Sbjct: 1005 EGEHCQFCRFGYYG--DALQQDCRKCVC 1030



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 44/155 (28%), Positives = 63/155 (40%), Gaps = 16/155 (10%)

Query: 353 GEYSTGYIDNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGT 412
           G  + G  D+ T  S   ++G       QC C +  +G+ C  C  G+  D +   PFG 
Sbjct: 404 GSQNEGICDSYTDFSTGLIAG-------QCRCKLNVEGEHCDVCKEGFY-DLSSEDPFG- 454

Query: 413 CIPCNCQ------GGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHN 466
           C  C C       GG  CD +TG CY         C  C    +   +D   C+PC C  
Sbjct: 455 CKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDL 514

Query: 467 GFSCSVMPETEEVVCNNCPPGVTGARCELCADGYF 501
           G + +     E   C +C P + G +C     GY+
Sbjct: 515 GGALNNSCFAESGQC-SCRPHMIGRQCNEVEPGYY 548



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 2/71 (2%)

Query: 56  CNDNTDGIHCEKCKNGFYR-HRERDRCLPCNCNSKGSLSARC-DNSGRCSCKPGVTGARC 113
           C     G HC++C    +    + D C PC+C+  G+L+  C   SG+CSC+P + G +C
Sbjct: 481 CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQC 540

Query: 114 DRCLPGFHMLT 124
           +   PG++  T
Sbjct: 541 NEVEPGYYFAT 551



 Score = 38.9 bits (89), Expect = 0.027
 Identities = 27/88 (30%), Positives = 33/88 (37%), Gaps = 13/88 (14%)

Query: 381  QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG----ACDPDTGD--CYSG 434
            QC C  G+ G+ C +C   +  D     P   C  C+C   G     CD  TG   C  G
Sbjct: 1102 QCQCMPGFGGRTCSECQELFWGD-----PDVECRACDCDPRGIETPQCDQSTGQCVCVEG 1156

Query: 435  DENPDIECADCPIGFYNDPHDPRSCKPC 462
             E P   C  C  G+     D   C  C
Sbjct: 1157 VEGP--RCDKCTRGYSGVFPDCTPCHQC 1182


>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
          Length = 1798

 Score =  159 bits (402), Expect = 1e-38
 Identities = 89/247 (36%), Positives = 113/247 (45%), Gaps = 36/247 (14%)

Query: 381  QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-GDENP 438
            QC+C  G  G  C  C  G          F +C PC C G    C+  TG C    D   
Sbjct: 849  QCLCRTGAFGLRCDRCQRGQ-------WGFPSCRPCVCNGHADECNTHTGACLGCRDHTG 901

Query: 439  DIECADCPIGFYNDPHDPRS--CKPCPC--------HNGFSCSVMPETEEVVCNNCPPGV 488
               C  C  GF+ DP  P    C+PCPC        H   SC     ++++VC+ C  G 
Sbjct: 902  GEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCH-CRAGY 960

Query: 489  TGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGI 548
            TG RCE CA G+FGDP    G    CQ C+C+ N+DP     CD  TG+CL+C+H+T G 
Sbjct: 961  TGLRCEACAPGHFGDPSRPGGR---CQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGP 1017

Query: 549  YCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC---------RSDGTCVCKPGFGG 599
            +C  CK G+ G          C  C CN +G+ P  C          S G C C P   G
Sbjct: 1018 HCAHCKPGFHGQA----ARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQG 1073

Query: 600  PNCEHGA 606
            P+C+  A
Sbjct: 1074 PSCDRCA 1080



 Score =  122 bits (305), Expect = 2e-27
 Identities = 171/750 (22%), Positives = 279/750 (37%), Gaps = 113/750 (15%)

Query: 382  CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG------GACDPDTGDCYS-- 433
            C C  GY G  C+ CA G+  D +R  P G C  C C G        ACDP TG C    
Sbjct: 954  CHCRAGYTGLRCEACAPGHFGDPSR--PGGRCQLCECSGNIDPMDPDACDPHTGQCLRCL 1011

Query: 434  -GDENPDIECADCPIGFYNDPHDPRSCKPCPCHN-GFSCSVMPETEEVVCN----NCP-- 485
               E P   CA C  GF+      +SC  C C+  G +    P  ++  C+     CP  
Sbjct: 1012 HHTEGP--HCAHCKPGFHGQAAR-QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCL 1068

Query: 486  PGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNT 545
            P V G  C+ CA  ++    G HG    CQPC C+ +   +    C+  TG+C  C    
Sbjct: 1069 PNVQGPSCDRCAPNFWNLTSG-HG----CQPCACHPS--RARGPTCNEFTGQC-HCRAGF 1120

Query: 546  AGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH 604
             G  C +C+  ++GDP       +C AC+C+  G +   C R  G C C+PG  G  C+ 
Sbjct: 1121 GGRTCSECQELHWGDP-----GLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQ 1175

Query: 605  GA--FS--------CPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQ 654
             A  FS        C AC+      +     + QR+E    + Q        T + G  +
Sbjct: 1176 CARGFSGIFPACHPCHACFGDWDRVVQDLAARTQRLEQRAQELQ-------QTGVLGAFE 1228

Query: 655  QAEQALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQN 714
             +   +Q+              LG+    V ++  S  S    ++ T E  R +G   ++
Sbjct: 1229 SSFWHMQE-------------KLGIVQGIVGARNTSAASTAQLVEATEELRREIGEATEH 1275

Query: 715  RVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEAT-RLAESHVE--S 771
                    +TQ++  L + +    N N     H +       LA   T R  + H++   
Sbjct: 1276 --------LTQLEADLTDVQDENFNAN-----HALSGLERDRLALNLTLRQLDQHLDLLK 1322

Query: 772  ASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLT 831
             SN             Q+    R+A    +   S   + A  +   E L   +       
Sbjct: 1323 HSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEALMDAQKEDFNSK 1382

Query: 832  REATQAEIEADRSYQHSLRLLD----------------SVSRLQGVSDQSFQVEEAKRIK 875
              A Q  +    ++ H+L L D                S     G  D+  Q        
Sbjct: 1383 HMANQRALGKLSAHTHTLSLTDINELVCGAPGDAPCATSPCGGAGCRDEDGQPRCGGLSC 1442

Query: 876  QKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQ 935
              A + + L    +   + TQ        E Q+ L  G S   +  +   +A+ A+ RAQ
Sbjct: 1443 NGAAATADLA---LGRARHTQ-------AELQRALAEGGSILSRVAETRRQASEAQQRAQ 1492

Query: 936  EALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAER 995
             AL   NA+  +VE   + L+E    V +   +       +  ++ +V + S     AE+
Sbjct: 1493 AALDKANASRGQVEQANQELQELIQSVKDFLNQEGADPDSIEMVATRVLELSIPA-SAEQ 1551

Query: 996  ALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMRE 1055
                A A A+R ++ A    ++ + + + +G +     +  D   A        K +   
Sbjct: 1552 IQHLAGAIAERVRSLA----DVDAILARTVGDVRRAEQLLQDARRA-RSWAEDEKQKAET 1606

Query: 1056 VEGELERKELEFDTNMDAVQMVITEAQKVD 1085
            V+  LE  +        A++  + + +  +
Sbjct: 1607 VQAALEEAQRAQGIAQGAIRGAVADTRDTE 1636



 Score =  114 bits (284), Expect = 7e-25
 Identities = 68/184 (36%), Positives = 89/184 (48%), Gaps = 28/184 (15%)

Query: 28  CDCNGKSRQCIFDRELHRQTGN--GFRCLNCNDNTDGIHCEKCKNGFYRHRERDR----- 80
           C+C+G +  C FD  ++  +GN  G  C  C  NT G HCE C+  FYR   +D      
Sbjct: 347 CECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAV 406

Query: 81  CLPCNCNSKGSLSA-RCDN---------SGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQ 130
           C  C+C+  GS    RCD+         SG+C CK  V G RC +C  GF      G + 
Sbjct: 407 CRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFF-----GLSI 461

Query: 131 DQRLLDSKCDCDPAGI---AGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCT 185
             RL   +C C+  G    + PCD  +G C CK  VTG  CDRC  G++ L   +  GC 
Sbjct: 462 SDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGL-SHDLLGCR 520

Query: 186 QCFC 189
            C C
Sbjct: 521 PCDC 524



 Score = 97.4 bits (241), Expect = 6e-20
 Identities = 46/121 (38%), Positives = 64/121 (52%), Gaps = 17/121 (14%)

Query: 82  LPCNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCD 140
           LPC CN +GSLS+ C+ + G+C CKPGV G RCD C PG++     GC          C 
Sbjct: 781 LPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGC--------QACQ 832

Query: 141 CDPAG-IAGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCR 197
           C   G ++  C+  +G+C+C+    G RCDRC+ G +         C  C C GH+  C 
Sbjct: 833 CSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGF-----PSCRPCVCNGHADECN 887

Query: 198 S 198
           +
Sbjct: 888 T 888



 Score = 95.1 bits (235), Expect = 3e-19
 Identities = 69/227 (30%), Positives = 87/227 (38%), Gaps = 62/227 (27%)

Query: 19   ARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRER 78
            +R   R ++C+C+G       D      TG   +CL C  +T+G HC  CK GF+    R
Sbjct: 977  SRPGGRCQLCECSGNIDPMDPDA-CDPHTG---QCLRCLHHTEGPHCAHCKPGFHGQAAR 1032

Query: 79   DRCLPCNCNSKGSLSARCDN---------SGRCSCKPGVTGARCDRCLPGFHMLTDA-GC 128
              C  C CN  G+   +C +         SG+C C P V G  CDRC P F  LT   GC
Sbjct: 1033 QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGC 1092

Query: 129  TQ----------------------------------------DQRLLDSKCDCDPAGIAG 148
                                                      D  L    CDCD  GI  
Sbjct: 1093 QPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDT 1152

Query: 149  P-CD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCF-CYG 191
            P C    G C C+P V+G RCD+C  G+     G    C  C  C+G
Sbjct: 1153 PQCHRFTGHCSCRPGVSGVRCDQCARGF----SGIFPACHPCHACFG 1195



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 58/160 (36%), Positives = 80/160 (50%), Gaps = 22/160 (13%)

Query: 28  CDCNGKSRQCIFDRELHRQTGNGF---RCLNCNDNTDGIHCEKCKNGFYRHRERDR--CL 82
           CDC+    Q     + H     G    +C  C ++  G  C++C++GF+     DR  C 
Sbjct: 410 CDCDPMGSQDGGRCDSHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFGLSISDRLGCR 468

Query: 83  PCNCNSKGSL--SARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTD--AGCTQDQRLLDS 137
            C CN++G++  S  CD NSG C CK  VTG  CDRCLPG   L+    GC         
Sbjct: 469 RCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGC--------R 520

Query: 138 KCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYY 174
            CDCD  G   P CD   G+C C+  + G RC++ + GY+
Sbjct: 521 PCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 75/273 (27%), Positives = 97/273 (35%), Gaps = 52/273 (19%)

Query: 370 PVSGAPAPWVEQ----CICPVGYKGQFCQDCASGYKR---DSARLGPFGTCIPCNCQG-- 420
           P  GAPA         CIC    +G  C+ C   Y+      A  G    C  C C G  
Sbjct: 294 PAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHT 353

Query: 421 -----------------GGACDPDTGDCYSGDENPDIECADCPIGFYNDP----HDPRSC 459
                            GG CD     C          C  C   FY DP     DP  C
Sbjct: 354 HSCHFDMAVYLASGNVSGGVCD----GCQHNTAGR--HCELCRPFFYRDPTKDLRDPAVC 407

Query: 460 KPCPC-----HNGFSCSVMPETEEVVCN---NCPPGVTGARCELCADGYFGDPFGEHGPV 511
           + C C      +G  C    +    + +    C   V G RC+ C DG+FG    +    
Sbjct: 408 RSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDR--- 464

Query: 512 RPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCR 571
             C+ CQCN       S  CD  +G C  C     G  CD+C  G++G     +    CR
Sbjct: 465 LGCRRCQCNARGTVPGSTPCDPNSGSCY-CKRLVTGRGCDRCLPGHWG---LSHDLLGCR 520

Query: 572 ACNCNPMGS-EPVGCRSDGTCVCKPGFGGPNCE 603
            C+C+  G+ +P      G C C+    G  CE
Sbjct: 521 PCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCE 553



 Score = 84.3 bits (207), Expect = 6e-16
 Identities = 54/145 (37%), Positives = 73/145 (50%), Gaps = 22/145 (15%)

Query: 461 PCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCN 520
           PC C+   S S         C  C PGV G RC+LCA GY+G  FG  G    CQ CQC+
Sbjct: 782 PCQCNPQGSLSSECNPHGGQCL-CKPGVVGRRCDLCAPGYYG--FGPTG----CQACQCS 834

Query: 521 NNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGS 580
           +  + + S  C++ +G+CL C     G+ CD+C+ G +G P        CR C CN    
Sbjct: 835 H--EGALSSLCEKTSGQCL-CRTGAFGLRCDRCQRGQWGFP-------SCRPCVCNGHAD 884

Query: 581 EPVGCRS-DGTCV-CKPGFGGPNCE 603
           E   C +  G C+ C+   GG +CE
Sbjct: 885 E---CNTHTGACLGCRDHTGGEHCE 906



 Score = 77.4 bits (189), Expect = 7e-14
 Identities = 60/206 (29%), Positives = 80/206 (38%), Gaps = 54/206 (26%)

Query: 28   CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFY---RHRERDRCLPC 84
            C CNG + +C      +  TG    CL C D+T G HCE+C  GF+   R     +C PC
Sbjct: 877  CVCNGHADEC------NTHTG---ACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPC 927

Query: 85   NC----NSKGSLSARCDNSGR-----CSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLL 135
             C     S+   +  C          C C+ G TG RC+ C PG           D    
Sbjct: 928  PCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHF--------GDPSRP 979

Query: 136  DSKCD-CDPAGIAGPCD-------AGRCV-CKPAVTGERCDRCRSGYY------------ 174
              +C  C+ +G   P D        G+C+ C     G  C  C+ G++            
Sbjct: 980  GGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCT 1039

Query: 175  -NLDGGNPEGC---TQCFCYGHSASC 196
             NL G NP+ C    QC C   S  C
Sbjct: 1040 CNLLGTNPQQCPSPDQCHCDPSSGQC 1065



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 56/196 (28%), Positives = 81/196 (41%), Gaps = 40/196 (20%)

Query: 28  CDCNGKSRQCIF--DRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR--------E 77
           C C G + +C        H +      C+ C  NT G++CE+C++ FYR           
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQD-FYRDLPWRPAEDGH 340

Query: 78  RDRCLPCNCNSKGS---------LSARCDNSGRCS-CKPGVTGARCDRCLPGFHMLTDAG 127
              C  C C+             L++   + G C  C+    G  C+ C P F+      
Sbjct: 341 SHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYR----D 396

Query: 128 CTQDQR--LLDSKCDCDPAGI--AGPCDA----------GRCVCKPAVTGERCDRCRSGY 173
            T+D R   +   CDCDP G    G CD+          G+C CK  V G RC +CR G+
Sbjct: 397 PTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGF 456

Query: 174 YNLDGGNPEGCTQCFC 189
           + L   +  GC +C C
Sbjct: 457 FGLSISDRLGCRRCQC 472



 Score = 70.5 bits (171), Expect = 8e-12
 Identities = 54/171 (31%), Positives = 74/171 (43%), Gaps = 33/171 (19%)

Query: 28  CDCNGK---SRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPC 84
           C CN +   S +C           +G +CL C     G  C+ C  G+Y       C  C
Sbjct: 783 CQCNPQGSLSSEC---------NPHGGQCL-CKPGVVGRRCDLCAPGYYGFGPTG-CQAC 831

Query: 85  NCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDP 143
            C+ +G+LS+ C+  SG+C C+ G  G RCDRC  G            Q    S   C  
Sbjct: 832 QCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRG------------QWGFPSCRPCVC 879

Query: 144 AGIAGPCD--AGRCV-CKPAVTGERCDRCRSGYYNLDGGNPEG--CTQCFC 189
            G A  C+   G C+ C+    GE C+RC +G++  D   P G  C  C C
Sbjct: 880 NGHADECNTHTGACLGCRDHTGGEHCERCIAGFHG-DPRLPYGGQCRPCPC 929



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 58/226 (25%), Positives = 88/226 (38%), Gaps = 34/226 (15%)

Query: 352 YGEYSTGYIDNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSAR-LGPF 410
           +G   + + D    +++  VSG          C     G+ C+ C   + RD  + L   
Sbjct: 350 HGHTHSCHFDMAVYLASGNVSGGVCDG-----CQHNTAGRHCELCRPFFYRDPTKDLRDP 404

Query: 411 GTCIPCNC-----QGGGACDPD--------TGDCYSGDENPDIECADCPIGFYN-DPHDP 456
             C  C+C     Q GG CD          +G C   +      C  C  GF+     D 
Sbjct: 405 AVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDR 464

Query: 457 RSCKPCPCHNGFSCSVMPETEEVVCNN----CPPGVTGARCELCADGYFGDPFGEHGPVR 512
             C+ C C+   +   +P +     N+    C   VTG  C+ C  G++G      G   
Sbjct: 465 LGCRRCQCN---ARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLG--- 518

Query: 513 PCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
            C+PC C+  V  +    CD  TG+C  C  +  G  C+Q + GYF
Sbjct: 519 -CRPCDCD--VGGALDPQCDEGTGQC-HCRQHMVGRRCEQVQPGYF 560



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 44/136 (32%), Positives = 54/136 (39%), Gaps = 14/136 (10%)

Query: 381 QCICPVGYKGQFCQDCASGY--KRDSARLGPFGTCIPCNCQGGGA------CDPDTGDCY 432
           QC C     G  CQ C  G+     S RLG    C  C C   G       CDP++G CY
Sbjct: 437 QCRCKEHVVGTRCQQCRDGFFGLSISDRLG----CRRCQCNARGTVPGSTPCDPNSGSCY 492

Query: 433 SGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGAR 492
                    C  C  G +   HD   C+PC C  G +     +     C +C   + G R
Sbjct: 493 CKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQC-HCRQHMVGRR 551

Query: 493 CELCADGYFGDPFGEH 508
           CE    GYF  PF +H
Sbjct: 552 CEQVQPGYF-RPFLDH 566



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 40/141 (28%), Positives = 55/141 (39%), Gaps = 15/141 (10%)

Query: 381  QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG----GGACDPDTGDCYSGDE 436
            QC C    +G  C  CA  +   ++  G    C PC C      G  C+  TG C+    
Sbjct: 1064 QCPCLPNVQGPSCDRCAPNFWNLTSGHG----CQPCACHPSRARGPTCNEFTGQCHCRAG 1119

Query: 437  NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
                 C++C    + DP     C  C C +    +         C+ C PGV+G RC+ C
Sbjct: 1120 FGGRTCSECQELHWGDPG--LQCHACDCDSRGIDTPQCHRFTGHCS-CRPGVSGVRCDQC 1176

Query: 497  ADGYFGDPFGEHGPVRPCQPC 517
            A G+ G     H    PC  C
Sbjct: 1177 ARGFSGIFPACH----PCHAC 1193



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 19/105 (18%)

Query: 17   PAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR 76
            P A   SR     CN  + QC                 +C     G  C +C+   +   
Sbjct: 1094 PCACHPSRARGPTCNEFTGQC-----------------HCRAGFGGRTCSECQELHWGDP 1136

Query: 77   ERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGF 120
               +C  C+C+S+G  + +C   +G CSC+PGV+G RCD+C  GF
Sbjct: 1137 GL-QCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGF 1180



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 5/49 (10%)

Query: 153 GRCVCKPAVTGERCDRCRSGYYNL-----DGGNPEGCTQCFCYGHSASC 196
           G C+CK    G  C++C+  Y +L     + G+   C +C C+GH+ SC
Sbjct: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSC 356



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 66/296 (22%), Positives = 122/296 (41%), Gaps = 42/296 (14%)

Query: 814  QGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRL-LDSVSRLQGVSDQSFQVEEAK 872
            Q L E ++  K    Q   +    E+ A R  + S+    + +  L G          A+
Sbjct: 1510 QELQELIQSVKDFLNQEGADPDSIEMVATRVLELSIPASAEQIQHLAGAI--------AE 1561

Query: 873  RIKQKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGR---EKSDQLLSRANL 929
            R++  AD + +++ R + + +R           A+QLLQ+ +  R   E   Q       
Sbjct: 1562 RVRSLAD-VDAILARTVGDVRR-----------AEQLLQDARRARSWAEDEKQKAETVQA 1609

Query: 930  AKSRAQEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDK 989
            A   AQ A  +         +  ++  +   QV  R A AE A+      ++++ DA  +
Sbjct: 1610 ALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQL-DALLE 1668

Query: 990  TQQAERALGSAAADAQRAKNGAGEALEISSEIEQ--------EIGSLNLEANVTADGALA 1041
              + +RA  S AA    A+  AG A   + E EQ        +  ++   A   A G LA
Sbjct: 1669 ALKLKRAGNSLAAST--AEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLA 1726

Query: 1042 MEKGLASLKSEMREV----EGELER-KELE--FDTNMDAVQMVITEAQKVDTRAKN 1090
             +     L+ E R++    + +L+R +ELE  ++ N  A++    +   ++ R ++
Sbjct: 1727 AQARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARMRS 1782



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 20/72 (27%), Positives = 29/72 (40%), Gaps = 10/72 (13%)

Query: 508 HGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAP--- 564
           +G    C P        P A  + + +      C HNT G+ C+QC+  Y   P  P   
Sbjct: 286 YGHASECAPA-------PGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAED 338

Query: 565 NPADKCRACNCN 576
             +  CR C C+
Sbjct: 339 GHSHACRKCECH 350


>gi|143770880 laminin, beta 4 [Homo sapiens]
          Length = 1761

 Score =  158 bits (399), Expect = 3e-38
 Identities = 83/233 (35%), Positives = 114/233 (48%), Gaps = 26/233 (11%)

Query: 381  QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-GDENP 438
            QC C     G+ C  C +GY         F +C PC C      CDP+TG C++ G    
Sbjct: 835  QCPCHGEVSGRRCDRCLAGYFG-------FPSCHPCPCNRFAELCDPETGSCFNCGGFTT 887

Query: 439  DIECADCPIGFYNDPHDPRSCKPCPCHN--------GFSCSVMPETEEVVCNNCPPGVTG 490
               C  C  G+Y +P   + C+PC C +          SC     + +V+CN C  G TG
Sbjct: 888  GRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICN-CLQGYTG 946

Query: 491  ARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYC 550
             +C  C+ G++G+P     P   CQPC CNNN+D +   +C R+TG CL+C+HNT G  C
Sbjct: 947  TQCGECSTGFYGNPRISGAP---CQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANC 1003

Query: 551  DQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNC 602
              CK G++G  L       CR C+C+  G  P+ C    G C+C P  G   C
Sbjct: 1004 QLCKPGHYGSAL----NQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPC 1052



 Score =  136 bits (342), Expect = 1e-31
 Identities = 178/807 (22%), Positives = 316/807 (39%), Gaps = 159/807 (19%)

Query: 382  CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG------GACDPDTGDCYSGD 435
            C C  GY G  C +C++G+  +    G    C PC C          +C   TG+C    
Sbjct: 938  CNCLQGYTGTQCGECSTGFYGNPRISG--APCQPCACNNNIDVTDPESCSRVTGECLRCL 995

Query: 436  ENPD-IECADCPIGFYNDPHDPRSCKPCPCH-----------NGFSCSVMPETEEVVCNN 483
             N     C  C  G Y    + ++C+ C CH            G +C   P T    C  
Sbjct: 996  HNTQGANCQLCKPGHYGSALN-QTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCL- 1053

Query: 484  CPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIH 543
              P VTG  C+ CADGY+        P R CQ C C+     S S +CD+LTG+C  C  
Sbjct: 1054 --PNVTGLACDRCADGYW-----NLVPGRGCQSCDCDPRT--SQSSHCDQLTGQC-PCKL 1103

Query: 544  NTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD-GTCVCKPGFGGPNC 602
               G  C +C+  Y+GD     P  +C  C+CN  G++   C  D G C C+ G  G  C
Sbjct: 1104 GYGGKRCSECQENYYGD-----PPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRC 1158

Query: 603  EHGA----------FSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTE---- 648
            +  A            C  C++Q    +    + +Q +  L +  +     +P  E    
Sbjct: 1159 DRCARGHSQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAANMEDKRETLPVCEADFK 1218

Query: 649  -LEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRL------DDLKMT 701
             L G + + E+    IL+      G    +      VR Q      +L       DLK T
Sbjct: 1219 DLRGNVSEIER----ILKHPVFPSGKFLKVKDYHDSVRRQIMQLNEQLKAVYEFQDLKDT 1274

Query: 702  VERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEA 761
            +ER +           +   L+  +Q  +    + L  +   +S++        S A++ 
Sbjct: 1275 IERAK----------NEADLLLEDLQEEIDLQSSVLNASIADSSENIKKYYHISSSAEKK 1324

Query: 762  TRLAESHVESASNM--EQLTRETEDYSKQALSLVR---------KALHEGVGSGSGSP-- 808
                 S + +++N   + LT      SK  LSL R         + L+E V    G+   
Sbjct: 1325 INETSSTINTSANTRNDLLTILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGDPGNVPC 1384

Query: 809  -----DGAVVQG---------------------LVEKLEKTKSLAQQLTREA----TQAE 838
                  GA+  G                      ++K ++ KS+ + L ++      Q E
Sbjct: 1385 VPLPCGGALCTGRKGHRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLKNQIE 1444

Query: 839  I---EADRSYQHSLRLLDSVSRLQGVSD-------------QSFQVEE---AKRIKQKAD 879
                +A+ S  ++L+L + +  ++  SD             ++F +EE    + I++ A+
Sbjct: 1445 SISEQAEVSKNNALQLREKLGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIEKVAN 1504

Query: 880  SLSSL---------------VTRHM---DEFKRTQKNLGNWKEEAQQLLQNGKSGREKSD 921
             +  +               + +HM   ++++  +  L    + AQ+LL   K+  + ++
Sbjct: 1505 GVLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENRLNEEADGAQKLLVKAKAAEKAAN 1564

Query: 922  QLLSRANLAKSRAQEALSMG--NATFYEVESILKNLREFDLQVDNRKAEAE---EAMKRL 976
             LL+         Q  ++ G  N+T  ++ + +  +++  LQ +N+  E +   E  K+ 
Sbjct: 1565 ILLNLDKTLNQLQQAQITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELELAKQR 1624

Query: 977  SYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANVTA 1036
            S +   +S    K Q+ +    +A   A+ A++ AG   +   E++++   L  + + T 
Sbjct: 1625 SGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKEFVELKKQYAILQRKTSTTG 1684

Query: 1037 DGALAMEKGLASLKSEMREVEGELERK 1063
                 + K +  LK    ++ G+ E K
Sbjct: 1685 LTKETLGK-VKQLKDAAEKLAGDTEAK 1710



 Score =  114 bits (286), Expect = 4e-25
 Identities = 62/183 (33%), Positives = 90/183 (49%), Gaps = 27/183 (14%)

Query: 28  CDCNGKSRQCIFDRELHRQTG--NGFRCLNCNDNTDGIHCEKCKNGFYRHRERD-----R 80
           C CN  S +C FD   +  +G  +G  C +C  NT+G HC++C+  FYR   +       
Sbjct: 332 CSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYA 391

Query: 81  CLPCNCNSKGSLS----------ARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQ 130
           C+PC C+  G++S          A    +G+C CK  V GA+CD+C P  +     G + 
Sbjct: 392 CIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHY-----GLSA 446

Query: 131 DQRLLDSKCDCDPAG----IAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQ 186
              L    CDC+P G    +    D G+C+C   VTG  C+ C  GY+ L G +  GC+ 
Sbjct: 447 TDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGL-GNHLHGCSP 505

Query: 187 CFC 189
           C C
Sbjct: 506 CDC 508



 Score =  113 bits (283), Expect = 9e-25
 Identities = 81/237 (34%), Positives = 110/237 (46%), Gaps = 33/237 (13%)

Query: 381  QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
            QC C     G+ C  C++G    S  LG  G C PC+C   G+    CD  TG C    E
Sbjct: 787  QCQCKPLVVGRCCDRCSTG----SYDLGHHG-CHPCHCHPQGSKDTVCDQVTGQCPCHGE 841

Query: 437  NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
                 C  C  G++  P    SC PCPC N F+    PET    C NC    TG  CE C
Sbjct: 842  VSGRRCDRCLAGYFGFP----SCHPCPC-NRFAELCDPETGS--CFNCGGFTTGRNCERC 894

Query: 497  ADGYFGDPFGEHGPVRPCQPCQCNNNVDPSA----SGNCDR---LTGRCLKCIHNTAGIY 549
             DGY+G+P       +PC+PC C +  DPS+    + +C +    +     C+    G  
Sbjct: 895  IDGYYGNP----SSGQPCRPCLCPD--DPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQ 948

Query: 550  CDQCKAGYFGDP-LAPNPADKCRACNCNPMGSEPVGC-RSDGTCV-CKPGFGGPNCE 603
            C +C  G++G+P ++  P   C ACN N   ++P  C R  G C+ C     G NC+
Sbjct: 949  CGECSTGFYGNPRISGAPCQPC-ACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQ 1004



 Score = 96.3 bits (238), Expect = 1e-19
 Identities = 60/177 (33%), Positives = 75/177 (42%), Gaps = 31/177 (17%)

Query: 28   CDCNGKSRQCIFDRE-LHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNC 86
            C CN      + D E   R TG    CL C  NT G +C+ CK G Y       C  C+C
Sbjct: 970  CACNNNID--VTDPESCSRVTGE---CLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSC 1024

Query: 87   NSKGSLSARCDN----------SGRCSCKPGVTGARCDRCLPGF-HMLTDAGCTQDQRLL 135
            ++ G     C            +G C C P VTG  CDRC  G+ +++   GC       
Sbjct: 1025 HASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGC------- 1077

Query: 136  DSKCDCDP-AGIAGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
               CDCDP    +  CD   G+C CK    G+RC  C+  YY   G  P  C  C C
Sbjct: 1078 -QSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYY---GDPPGRCIPCDC 1130



 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 64/202 (31%), Positives = 89/202 (44%), Gaps = 43/202 (21%)

Query: 25  REVCDCNGKSRQCIFDRELHRQTGNGF--------RCLNCNDNTDGIHCEKCKNGFYRHR 76
           R  C CNG + +C   R + +  G+ F        +C+ C  NTDG +CE+CK+ F    
Sbjct: 262 RGSCFCNGHASEC---RPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAP 317

Query: 77  ER-------DRCLPCNCNSKGS---------LSARCDNSGRCS-CKPGVTGARCDRCLPG 119
            R       + C  C+CNS  S         L++   + G C  C+    G  CDRC P 
Sbjct: 318 WRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPL 377

Query: 120 FHMLTDAGCTQDQRLLDSKCDCDPAGI--AGPCD----------AGRCVCKPAVTGERCD 167
           F+   D   T         C+CDP G    G C           AG+C+CK  V G +CD
Sbjct: 378 FYR--DPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCD 435

Query: 168 RCRSGYYNLDGGNPEGCTQCFC 189
           +C+  +Y L   +P GC  C C
Sbjct: 436 QCKPNHYGLSATDPLGCQPCDC 457



 Score = 90.5 bits (223), Expect = 8e-18
 Identities = 75/266 (28%), Positives = 100/266 (37%), Gaps = 59/266 (22%)

Query: 381 QCICPVGYKGQFCQDCASGYK----RDSARLGPFGTCIPCNCQG---------------- 420
           QC+C     G  C+ C   ++    R +A L     C  C+C                  
Sbjct: 294 QCVCQHNTDGPNCERCKDFFQDAPWRPAADLQD-NACRSCSCNSHSSRCHFDMTTYLASG 352

Query: 421 ---GGACDPDTGDCYSGDENPDIECADCPIGFYNDP----HDPRSCKPCPCH------NG 467
              GG C+    DC    E     C  C   FY DP     DP +C PC C        G
Sbjct: 353 GLSGGVCE----DCQHNTEGQ--HCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGG 406

Query: 468 FSCSVMPETEEVVCNNC--PPGVTGARCELCADGYFG----DPFGEHGPVRPCQPCQCNN 521
              S        V   C     V GA+C+ C   ++G    DP G       CQPC CN 
Sbjct: 407 ICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLG-------CQPCDCNP 459

Query: 522 NVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581
            +       CD  TG+CL C+    G +C++C  GY+G     N    C  C+C+  G+ 
Sbjct: 460 -LGSLPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWG---LGNHLHGCSPCDCDIGGAY 514

Query: 582 PVGCR-SDGTCVCKPGFGGPNCEHGA 606
              C   +G C C+P   G +C   A
Sbjct: 515 SNVCSPKNGQCECRPHVTGRSCSEPA 540



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 49/162 (30%), Positives = 74/162 (45%), Gaps = 20/162 (12%)

Query: 56   CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
            C  N  G+ C++C +G++       C  C+C+ + S S+ CD  +G+C CK G  G RC 
Sbjct: 1052 CLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCS 1111

Query: 115  RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPC---DAGRCVCKPAVTGERCDRCRS 171
             C   ++      C          CDC+ AG   P    D G C C+  V+G+RCDRC  
Sbjct: 1112 ECQENYYGDPPGRCIP--------CDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCAR 1163

Query: 172  GYYNLDGGNPEGCTQC-FCY---GHSASCRSSAEYSVHKITS 209
            G+          C QC  C+    H+ S  S A   + ++ +
Sbjct: 1164 GH----SQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAA 1201



 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 48/157 (30%), Positives = 71/157 (45%), Gaps = 17/157 (10%)

Query: 79  DRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDS 137
           D  + C C+ +GS+ + C    G+C CKP V G  CDRC  G + L   GC         
Sbjct: 764 DGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGC--------H 815

Query: 138 KCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQC--FCYGH 192
            C C P G     CD   G+C C   V+G RCDRC +GY+     +P  C +    C   
Sbjct: 816 PCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPE 875

Query: 193 SASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAK 229
           + SC +   ++  +      + +DG+     +G P +
Sbjct: 876 TGSCFNCGGFTTGR---NCERCIDGYYGNPSSGQPCR 909



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 63/228 (27%), Positives = 86/228 (37%), Gaps = 41/228 (17%)

Query: 408 GPFGTCIPCNCQGGGACDPDT---GDCYSGDENPDIECADCPIGFYNDPHDP------RS 458
           G    C P     G    P     G C          C  C   F + P  P       +
Sbjct: 269 GHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNA 328

Query: 459 CKPCPCHNGFSCSVMPETEEV--------VCNNCPPGVTGARCELCADGYFGDPFGEHGP 510
           C+ C C++  S      T  +        VC +C     G  C+ C   ++ DP      
Sbjct: 329 CRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISD 388

Query: 511 VRPCQPCQCNNNVDPSASGN---------CDRLTGRCLKCIHNTAGIYCDQCKAGYFG-- 559
              C PC+C  + D + SG             + G+CL C  N  G  CDQCK  ++G  
Sbjct: 389 PYACIPCEC--DPDGTISGGICVSHSDPALGSVAGQCL-CKENVEGAKCDQCKPNHYGLS 445

Query: 560 --DPLAPNPADKCRACNCNPMGSEP-VGCRSD-GTCVCKPGFGGPNCE 603
             DPL       C+ C+CNP+GS P + C  D G C+C     G +CE
Sbjct: 446 ATDPLG------CQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCE 487



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 42/129 (32%), Positives = 55/129 (42%), Gaps = 8/129 (6%)

Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA-----CDPDTGDCYSGD 435
           QC+C    +G  C  C   +   SA   P G C PC+C   G+     CD DTG C    
Sbjct: 422 QCLCKENVEGAKCDQCKPNHYGLSAT-DPLG-CQPCDCNPLGSLPFLTCDVDTGQCLCLS 479

Query: 436 ENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCEL 495
                 C +C +G++   +    C PC C  G + S +   +   C  C P VTG  C  
Sbjct: 480 YVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQC-ECRPHVTGRSCSE 538

Query: 496 CADGYFGDP 504
            A GYF  P
Sbjct: 539 PAPGYFFAP 547



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 59/231 (25%), Positives = 80/231 (34%), Gaps = 80/231 (34%)

Query: 28   CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR-CLPCNC 86
            C CN  +  C        +TG+   C NC   T G +CE+C +G+Y +    + C PC C
Sbjct: 863  CPCNRFAELC------DPETGS---CFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLC 913

Query: 87   ----NSKGSLSARC-----DNSGRCSCKPGVTGARCDRCLPGFH--------MLTDAGCT 129
                +S    +  C      +   C+C  G TG +C  C  GF+              C 
Sbjct: 914  PDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACN 973

Query: 130  QDQRLLD---------------------------------------SKCDCDPAGI---- 146
             +  + D                                        +C C  +G+    
Sbjct: 974  NNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPME 1033

Query: 147  ------AGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
                  A  CD   G C C P VTG  CDRC  GY+NL  G   GC  C C
Sbjct: 1034 CPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPG--RGCQSCDC 1082



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 42/135 (31%), Positives = 56/135 (41%), Gaps = 18/135 (13%)

Query: 370  PVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNC----QGGGACD 425
            PV+GA       C C     G  C  CA GY      L P   C  C+C         CD
Sbjct: 1045 PVTGA-------CPCLPNVTGLACDRCADGY----WNLVPGRGCQSCDCDPRTSQSSHCD 1093

Query: 426  PDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCP 485
              TG C          C++C   +Y DP  P  C PC C+   +   + + +  +C  C 
Sbjct: 1094 QLTGQCPCKLGYGGKRCSECQENYYGDP--PGRCIPCDCNRAGTQKPICDPDTGMC-RCR 1150

Query: 486  PGVTGARCELCADGY 500
             GV+G RC+ CA G+
Sbjct: 1151 EGVSGQRCDRCARGH 1165



 Score = 57.8 bits (138), Expect = 6e-08
 Identities = 43/149 (28%), Positives = 59/149 (39%), Gaps = 29/149 (19%)

Query: 56  CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCD-NSGRC-SCKPGVTGARC 113
           C+    G  C++C  G++       C PC CN    L   CD  +G C +C    TG  C
Sbjct: 838 CHGEVSGRRCDRCLAGYFGF---PSCHPCPCNRFAEL---CDPETGSCFNCGGFTTGRNC 891

Query: 114 DRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAG---IAGPCDAGR------CVCKPAVTGE 164
           +RC+ G++    +G    Q      C  DP+     A  C          C C    TG 
Sbjct: 892 ERCIDGYYGNPSSG----QPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGT 947

Query: 165 RCDRCRSGYYNLDGGNPE----GCTQCFC 189
           +C  C +G+Y    GNP      C  C C
Sbjct: 948 QCGECSTGFY----GNPRISGAPCQPCAC 972



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 9/86 (10%)

Query: 381  QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
            QC C +GY G+ C +C   Y  D     P G CIPC+C   G     CDPDTG C   + 
Sbjct: 1098 QCPCKLGYGGKRCSECQENYYGD-----PPGRCIPCDCNRAGTQKPICDPDTGMCRCREG 1152

Query: 437  NPDIECADCPIGFYNDPHDPRSCKPC 462
                 C  C  G   +      C  C
Sbjct: 1153 VSGQRCDRCARGHSQEFPTCLQCHLC 1178



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 32/95 (33%), Positives = 45/95 (47%), Gaps = 8/95 (8%)

Query: 28  CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYR-HRERDRCLPCNC 86
           CDCN          ++   TG   +CL C     G HCE+C  G++        C PC+C
Sbjct: 455 CDCNPLGSLPFLTCDV--DTG---QCL-CLSYVTGAHCEECTVGYWGLGNHLHGCSPCDC 508

Query: 87  NSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGF 120
           +  G+ S  C   +G+C C+P VTG  C    PG+
Sbjct: 509 DIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGY 543



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 10/99 (10%)

Query: 519 CNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPM 578
           C  +   S   +C RL G+C +C     G  CD+C  G +           C  C+C+P 
Sbjct: 769 CKCHPQGSVGSSCSRLGGQC-QCKPLVVGRCCDRCSTGSYD-----LGHHGCHPCHCHPQ 822

Query: 579 GSEPVGC-RSDGTCVCKPGFGGPNCEH---GAFSCPACY 613
           GS+   C +  G C C     G  C+    G F  P+C+
Sbjct: 823 GSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCH 861



 Score = 34.3 bits (77), Expect = 0.67
 Identities = 14/49 (28%), Positives = 21/49 (42%), Gaps = 5/49 (10%)

Query: 153 GRCVCKPAVTGERCDRCRSGYYNLDGG-----NPEGCTQCFCYGHSASC 196
           G+CVC+    G  C+RC+  + +             C  C C  HS+ C
Sbjct: 293 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRC 341



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 19/55 (34%), Positives = 22/55 (40%), Gaps = 9/55 (16%)

Query: 568 DKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH--------GAFSCPACY 613
           D   AC C+P GS    C R  G C CKP   G  C+         G   C  C+
Sbjct: 764 DGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCH 818



 Score = 30.4 bits (67), Expect = 9.7
 Identities = 14/41 (34%), Positives = 19/41 (46%), Gaps = 6/41 (14%)

Query: 377  PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCN 417
            P    C C  G  GQ C  CA G+ ++      F TC+ C+
Sbjct: 1142 PDTGMCRCREGVSGQRCDRCARGHSQE------FPTCLQCH 1176


>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
          Length = 1172

 Score =  135 bits (340), Expect = 2e-31
 Identities = 158/731 (21%), Positives = 288/731 (39%), Gaps = 84/731 (11%)

Query: 389  KGQFCQDCASGY---KRDSARLGPFGTCIPCNCQGGGA-----CDPDTGDCYSGDENPDI 440
            +G+ C+ C   Y   +R  A +    TCI C C   GA     CDP TG C   +     
Sbjct: 351  EGKNCERCQLHYFRNRRPGASIQE--TCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGE 408

Query: 441  ECADCPIGFYNDPH-DPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADG 499
             C  C  GF    + +P+ C  C C+   S   MP  EE     C P V G +C+ CA  
Sbjct: 409  RCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPY 468

Query: 500  YFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFG 559
            ++    G+      C+PC C+ +   S S  C++ TG+C  C     G+ C         
Sbjct: 469  HWKLASGQ-----GCEPCACDPH--NSLSPQCNQFTGQC-PCREGFGGLMCSAAAIRQCP 520

Query: 560  DPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH----------GAFS 608
            D    + A  CRAC+C+  G+E  GC ++ G C+C+PG  GP C+              +
Sbjct: 521  DRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA 580

Query: 609  CPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQ 668
            C  C+      + +   +  R+    +    G G + D  L  R+  A+  ++ I   A 
Sbjct: 581  CHPCFQTYDADLREQALRFGRLRNATASLWSGPG-LEDRGLASRILDAKSKIEQI--RAV 637

Query: 669  ISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTV---ERVRALGSQYQNRVRDTHRLITQ 725
            +S  A      ++A+V S   S +  L  L++ +   E   +L    ++  R  + L+T 
Sbjct: 638  LSSPAVTE--QEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTM 695

Query: 726  MQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDY 785
             Q    + E       I ++D    P+G   +   A   +    +  S+  +L  +  D 
Sbjct: 696  YQRKREQFE------KISSAD----PSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDS 745

Query: 786  SKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAE------- 838
             ++A  LVR+A   G G G+GSP    ++  +  L        +L   + Q         
Sbjct: 746  RREAERLVRQA---GGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCP 802

Query: 839  ---IEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRT 895
                  D       R    + R  G    + QV E  R        ++ + R     +  
Sbjct: 803  GELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR------GFNAQLQRTRQMIRAA 856

Query: 896  QKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNL 955
            +++    +  AQ+L     + R + ++ + R  L   + ++ L+  +     ++ + + +
Sbjct: 857  EESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAV 916

Query: 956  REFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEAL 1015
                L  D+  A   + M  +  I+ ++ +      Q ++ +  A      A+     A 
Sbjct: 917  LALWLPTDS--ATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAH 974

Query: 1016 EISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQ 1075
             +  ++E  +G+L         G +A+++   +++   R +    +R        +  VQ
Sbjct: 975  AVEGQVEDVVGNLR-------QGTVALQEAQDTMQGTSRSLRLIQDR--------VAEVQ 1019

Query: 1076 MVITEAQKVDT 1086
             V+  A+K+ T
Sbjct: 1020 QVLRPAEKLVT 1030



 Score =  124 bits (312), Expect = 4e-28
 Identities = 71/183 (38%), Positives = 99/183 (54%), Gaps = 26/183 (14%)

Query: 28  CDCNGKSRQCIFDRELHR--QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRE-----RDR 80
           CDCNG S  C FD  +    Q   G  C NC D+T+G +CE+C+  ++R+R      ++ 
Sbjct: 316 CDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET 375

Query: 81  CLPCNCNSKGSL-SARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLL 135
           C+ C C+  G++  A CD  +G+C CK  V G RCD C PGF  LT A   GC       
Sbjct: 376 CISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC------- 428

Query: 136 DSKCDCDPAGIAG--PCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYG 191
             +CDC+  G     PCD  +GRC+C P V G +CD+C   ++ L  G  +GC  C C  
Sbjct: 429 -HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASG--QGCEPCACDP 485

Query: 192 HSA 194
           H++
Sbjct: 486 HNS 488



 Score = 91.3 bits (225), Expect = 5e-18
 Identities = 52/159 (32%), Positives = 71/159 (44%), Gaps = 31/159 (19%)

Query: 56  CNDNTDGIHCEKCKNGFYRHR--------ERDRCLPCNCN---------------SKGSL 92
           C  NT G +CE+C   FY +R        +   C  C+CN               S+G+ 
Sbjct: 281 CQHNTAGPNCERCAP-FYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAY 339

Query: 93  SARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCD- 151
              CDN     C+    G  C+RC   +      G +  +  +  +CD D A    PCD 
Sbjct: 340 GGVCDN-----CRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDP 394

Query: 152 -AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
             G+CVCK  V GERCD C+ G+  L   NP+GC +C C
Sbjct: 395 VTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDC 433



 Score = 89.4 bits (220), Expect = 2e-17
 Identities = 56/159 (35%), Positives = 74/159 (46%), Gaps = 27/159 (16%)

Query: 28  CDCN--GKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCN 85
           CDCN  G  R    D E         RCL C  N  G  C++C    ++      C PC 
Sbjct: 431 CDCNILGSRRDMPCDEE-------SGRCL-CLPNVVGPKCDQCAPYHWKLASGQGCEPCA 482

Query: 86  CNSKGSLSARCDN-SGRCSCKPGVTGARCD-----RCLPGFHMLTDAGCTQDQRLLDSKC 139
           C+   SLS +C+  +G+C C+ G  G  C      +C    +     GC          C
Sbjct: 483 CDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA--------C 534

Query: 140 DCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYYN 175
           DCD  G  GP CD  +GRC+C+P +TG RCD+C+ GY N
Sbjct: 535 DCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCN 573



 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 71/247 (28%), Positives = 93/247 (37%), Gaps = 42/247 (17%)

Query: 416 CNCQGGGACDPDTGD-----CYSGDENPDIECADCPIGFYNDP------HDPRSCKPCPC 464
           C  + G +  P T       C          C  C   + N P       D   C+ C C
Sbjct: 259 CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDC 318

Query: 465 HNGFS--CSVMPETEEV-------VCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQ 515
            NG S  C   P            VC+NC     G  CE C   YF +          C 
Sbjct: 319 -NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCI 377

Query: 516 PCQCN-NNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACN 574
            C+C+ +   P A   CD +TG+C+ C  +  G  CD CK G+ G   A NP   C  C+
Sbjct: 378 SCECDPDGAVPGAP--CDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYA-NP-QGCHRCD 432

Query: 575 CNPMGS-EPVGC-RSDGTCVCKPGFGGPNCEHGA---------FSCPAC----YNQVKIQ 619
           CN +GS   + C    G C+C P   GP C+  A           C  C    +N +  Q
Sbjct: 433 CNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQ 492

Query: 620 MDQFMQQ 626
            +QF  Q
Sbjct: 493 CNQFTGQ 499



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 9/68 (13%)

Query: 138 KCDCDPAGIAGPCDAGR----CVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCF 188
           +C   P   AGP  A +    CVC+    G  C+RC   Y N      +G +   C +C 
Sbjct: 258 RCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCD 317

Query: 189 CYGHSASC 196
           C GHS +C
Sbjct: 318 CNGHSETC 325


>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
          Length = 1172

 Score =  135 bits (340), Expect = 2e-31
 Identities = 158/731 (21%), Positives = 288/731 (39%), Gaps = 84/731 (11%)

Query: 389  KGQFCQDCASGY---KRDSARLGPFGTCIPCNCQGGGA-----CDPDTGDCYSGDENPDI 440
            +G+ C+ C   Y   +R  A +    TCI C C   GA     CDP TG C   +     
Sbjct: 351  EGKNCERCQLHYFRNRRPGASIQE--TCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGE 408

Query: 441  ECADCPIGFYNDPH-DPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADG 499
             C  C  GF    + +P+ C  C C+   S   MP  EE     C P V G +C+ CA  
Sbjct: 409  RCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPY 468

Query: 500  YFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFG 559
            ++    G+      C+PC C+ +   S S  C++ TG+C  C     G+ C         
Sbjct: 469  HWKLASGQ-----GCEPCACDPH--NSLSPQCNQFTGQC-PCREGFGGLMCSAAAIRQCP 520

Query: 560  DPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH----------GAFS 608
            D    + A  CRAC+C+  G+E  GC ++ G C+C+PG  GP C+              +
Sbjct: 521  DRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA 580

Query: 609  CPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQ 668
            C  C+      + +   +  R+    +    G G + D  L  R+  A+  ++ I   A 
Sbjct: 581  CHPCFQTYDADLREQALRFGRLRNATASLWSGPG-LEDRGLASRILDAKSKIEQI--RAV 637

Query: 669  ISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTV---ERVRALGSQYQNRVRDTHRLITQ 725
            +S  A      ++A+V S   S +  L  L++ +   E   +L    ++  R  + L+T 
Sbjct: 638  LSSPAVTE--QEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTM 695

Query: 726  MQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDY 785
             Q    + E       I ++D    P+G   +   A   +    +  S+  +L  +  D 
Sbjct: 696  YQRKREQFE------KISSAD----PSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDS 745

Query: 786  SKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAE------- 838
             ++A  LVR+A   G G G+GSP    ++  +  L        +L   + Q         
Sbjct: 746  RREAERLVRQA---GGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCP 802

Query: 839  ---IEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRT 895
                  D       R    + R  G    + QV E  R        ++ + R     +  
Sbjct: 803  GELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR------GFNAQLQRTRQMIRAA 856

Query: 896  QKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNL 955
            +++    +  AQ+L     + R + ++ + R  L   + ++ L+  +     ++ + + +
Sbjct: 857  EESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAV 916

Query: 956  REFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEAL 1015
                L  D+  A   + M  +  I+ ++ +      Q ++ +  A      A+     A 
Sbjct: 917  LALWLPTDS--ATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAH 974

Query: 1016 EISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQ 1075
             +  ++E  +G+L         G +A+++   +++   R +    +R        +  VQ
Sbjct: 975  AVEGQVEDVVGNLR-------QGTVALQEAQDTMQGTSRSLRLIQDR--------VAEVQ 1019

Query: 1076 MVITEAQKVDT 1086
             V+  A+K+ T
Sbjct: 1020 QVLRPAEKLVT 1030



 Score =  124 bits (312), Expect = 4e-28
 Identities = 71/183 (38%), Positives = 99/183 (54%), Gaps = 26/183 (14%)

Query: 28  CDCNGKSRQCIFDRELHR--QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRE-----RDR 80
           CDCNG S  C FD  +    Q   G  C NC D+T+G +CE+C+  ++R+R      ++ 
Sbjct: 316 CDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET 375

Query: 81  CLPCNCNSKGSL-SARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLL 135
           C+ C C+  G++  A CD  +G+C CK  V G RCD C PGF  LT A   GC       
Sbjct: 376 CISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC------- 428

Query: 136 DSKCDCDPAGIAG--PCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYG 191
             +CDC+  G     PCD  +GRC+C P V G +CD+C   ++ L  G  +GC  C C  
Sbjct: 429 -HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASG--QGCEPCACDP 485

Query: 192 HSA 194
           H++
Sbjct: 486 HNS 488



 Score = 91.3 bits (225), Expect = 5e-18
 Identities = 52/159 (32%), Positives = 71/159 (44%), Gaps = 31/159 (19%)

Query: 56  CNDNTDGIHCEKCKNGFYRHR--------ERDRCLPCNCN---------------SKGSL 92
           C  NT G +CE+C   FY +R        +   C  C+CN               S+G+ 
Sbjct: 281 CQHNTAGPNCERCAP-FYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAY 339

Query: 93  SARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCD- 151
              CDN     C+    G  C+RC   +      G +  +  +  +CD D A    PCD 
Sbjct: 340 GGVCDN-----CRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDP 394

Query: 152 -AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
             G+CVCK  V GERCD C+ G+  L   NP+GC +C C
Sbjct: 395 VTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDC 433



 Score = 89.4 bits (220), Expect = 2e-17
 Identities = 56/159 (35%), Positives = 74/159 (46%), Gaps = 27/159 (16%)

Query: 28  CDCN--GKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCN 85
           CDCN  G  R    D E         RCL C  N  G  C++C    ++      C PC 
Sbjct: 431 CDCNILGSRRDMPCDEE-------SGRCL-CLPNVVGPKCDQCAPYHWKLASGQGCEPCA 482

Query: 86  CNSKGSLSARCDN-SGRCSCKPGVTGARCD-----RCLPGFHMLTDAGCTQDQRLLDSKC 139
           C+   SLS +C+  +G+C C+ G  G  C      +C    +     GC          C
Sbjct: 483 CDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA--------C 534

Query: 140 DCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYYN 175
           DCD  G  GP CD  +GRC+C+P +TG RCD+C+ GY N
Sbjct: 535 DCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCN 573



 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 71/247 (28%), Positives = 93/247 (37%), Gaps = 42/247 (17%)

Query: 416 CNCQGGGACDPDTGD-----CYSGDENPDIECADCPIGFYNDP------HDPRSCKPCPC 464
           C  + G +  P T       C          C  C   + N P       D   C+ C C
Sbjct: 259 CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDC 318

Query: 465 HNGFS--CSVMPETEEV-------VCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQ 515
            NG S  C   P            VC+NC     G  CE C   YF +          C 
Sbjct: 319 -NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCI 377

Query: 516 PCQCN-NNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACN 574
            C+C+ +   P A   CD +TG+C+ C  +  G  CD CK G+ G   A NP   C  C+
Sbjct: 378 SCECDPDGAVPGAP--CDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYA-NP-QGCHRCD 432

Query: 575 CNPMGS-EPVGC-RSDGTCVCKPGFGGPNCEHGA---------FSCPAC----YNQVKIQ 619
           CN +GS   + C    G C+C P   GP C+  A           C  C    +N +  Q
Sbjct: 433 CNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQ 492

Query: 620 MDQFMQQ 626
            +QF  Q
Sbjct: 493 CNQFTGQ 499



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 9/68 (13%)

Query: 138 KCDCDPAGIAGPCDAGR----CVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCF 188
           +C   P   AGP  A +    CVC+    G  C+RC   Y N      +G +   C +C 
Sbjct: 258 RCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCD 317

Query: 189 CYGHSASC 196
           C GHS +C
Sbjct: 318 CNGHSETC 325


>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
          Length = 1172

 Score =  135 bits (340), Expect = 2e-31
 Identities = 158/731 (21%), Positives = 288/731 (39%), Gaps = 84/731 (11%)

Query: 389  KGQFCQDCASGY---KRDSARLGPFGTCIPCNCQGGGA-----CDPDTGDCYSGDENPDI 440
            +G+ C+ C   Y   +R  A +    TCI C C   GA     CDP TG C   +     
Sbjct: 351  EGKNCERCQLHYFRNRRPGASIQE--TCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGE 408

Query: 441  ECADCPIGFYNDPH-DPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADG 499
             C  C  GF    + +P+ C  C C+   S   MP  EE     C P V G +C+ CA  
Sbjct: 409  RCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPY 468

Query: 500  YFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFG 559
            ++    G+      C+PC C+ +   S S  C++ TG+C  C     G+ C         
Sbjct: 469  HWKLASGQ-----GCEPCACDPH--NSLSPQCNQFTGQC-PCREGFGGLMCSAAAIRQCP 520

Query: 560  DPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH----------GAFS 608
            D    + A  CRAC+C+  G+E  GC ++ G C+C+PG  GP C+              +
Sbjct: 521  DRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA 580

Query: 609  CPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQ 668
            C  C+      + +   +  R+    +    G G + D  L  R+  A+  ++ I   A 
Sbjct: 581  CHPCFQTYDADLREQALRFGRLRNATASLWSGPG-LEDRGLASRILDAKSKIEQI--RAV 637

Query: 669  ISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTV---ERVRALGSQYQNRVRDTHRLITQ 725
            +S  A      ++A+V S   S +  L  L++ +   E   +L    ++  R  + L+T 
Sbjct: 638  LSSPAVTE--QEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTM 695

Query: 726  MQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDY 785
             Q    + E       I ++D    P+G   +   A   +    +  S+  +L  +  D 
Sbjct: 696  YQRKREQFE------KISSAD----PSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDS 745

Query: 786  SKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAE------- 838
             ++A  LVR+A   G G G+GSP    ++  +  L        +L   + Q         
Sbjct: 746  RREAERLVRQA---GGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCP 802

Query: 839  ---IEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRT 895
                  D       R    + R  G    + QV E  R        ++ + R     +  
Sbjct: 803  GELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR------GFNAQLQRTRQMIRAA 856

Query: 896  QKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNL 955
            +++    +  AQ+L     + R + ++ + R  L   + ++ L+  +     ++ + + +
Sbjct: 857  EESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAV 916

Query: 956  REFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEAL 1015
                L  D+  A   + M  +  I+ ++ +      Q ++ +  A      A+     A 
Sbjct: 917  LALWLPTDS--ATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAH 974

Query: 1016 EISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQ 1075
             +  ++E  +G+L         G +A+++   +++   R +    +R        +  VQ
Sbjct: 975  AVEGQVEDVVGNLR-------QGTVALQEAQDTMQGTSRSLRLIQDR--------VAEVQ 1019

Query: 1076 MVITEAQKVDT 1086
             V+  A+K+ T
Sbjct: 1020 QVLRPAEKLVT 1030



 Score =  124 bits (312), Expect = 4e-28
 Identities = 71/183 (38%), Positives = 99/183 (54%), Gaps = 26/183 (14%)

Query: 28  CDCNGKSRQCIFDRELHR--QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRE-----RDR 80
           CDCNG S  C FD  +    Q   G  C NC D+T+G +CE+C+  ++R+R      ++ 
Sbjct: 316 CDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET 375

Query: 81  CLPCNCNSKGSL-SARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLL 135
           C+ C C+  G++  A CD  +G+C CK  V G RCD C PGF  LT A   GC       
Sbjct: 376 CISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC------- 428

Query: 136 DSKCDCDPAGIAG--PCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYG 191
             +CDC+  G     PCD  +GRC+C P V G +CD+C   ++ L  G  +GC  C C  
Sbjct: 429 -HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASG--QGCEPCACDP 485

Query: 192 HSA 194
           H++
Sbjct: 486 HNS 488



 Score = 91.3 bits (225), Expect = 5e-18
 Identities = 52/159 (32%), Positives = 71/159 (44%), Gaps = 31/159 (19%)

Query: 56  CNDNTDGIHCEKCKNGFYRHR--------ERDRCLPCNCN---------------SKGSL 92
           C  NT G +CE+C   FY +R        +   C  C+CN               S+G+ 
Sbjct: 281 CQHNTAGPNCERCAP-FYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAY 339

Query: 93  SARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCD- 151
              CDN     C+    G  C+RC   +      G +  +  +  +CD D A    PCD 
Sbjct: 340 GGVCDN-----CRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDP 394

Query: 152 -AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
             G+CVCK  V GERCD C+ G+  L   NP+GC +C C
Sbjct: 395 VTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDC 433



 Score = 89.4 bits (220), Expect = 2e-17
 Identities = 56/159 (35%), Positives = 74/159 (46%), Gaps = 27/159 (16%)

Query: 28  CDCN--GKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCN 85
           CDCN  G  R    D E         RCL C  N  G  C++C    ++      C PC 
Sbjct: 431 CDCNILGSRRDMPCDEE-------SGRCL-CLPNVVGPKCDQCAPYHWKLASGQGCEPCA 482

Query: 86  CNSKGSLSARCDN-SGRCSCKPGVTGARCD-----RCLPGFHMLTDAGCTQDQRLLDSKC 139
           C+   SLS +C+  +G+C C+ G  G  C      +C    +     GC          C
Sbjct: 483 CDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA--------C 534

Query: 140 DCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYYN 175
           DCD  G  GP CD  +GRC+C+P +TG RCD+C+ GY N
Sbjct: 535 DCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCN 573



 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 71/247 (28%), Positives = 93/247 (37%), Gaps = 42/247 (17%)

Query: 416 CNCQGGGACDPDTGD-----CYSGDENPDIECADCPIGFYNDP------HDPRSCKPCPC 464
           C  + G +  P T       C          C  C   + N P       D   C+ C C
Sbjct: 259 CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDC 318

Query: 465 HNGFS--CSVMPETEEV-------VCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQ 515
            NG S  C   P            VC+NC     G  CE C   YF +          C 
Sbjct: 319 -NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCI 377

Query: 516 PCQCN-NNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACN 574
            C+C+ +   P A   CD +TG+C+ C  +  G  CD CK G+ G   A NP   C  C+
Sbjct: 378 SCECDPDGAVPGAP--CDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYA-NP-QGCHRCD 432

Query: 575 CNPMGS-EPVGC-RSDGTCVCKPGFGGPNCEHGA---------FSCPAC----YNQVKIQ 619
           CN +GS   + C    G C+C P   GP C+  A           C  C    +N +  Q
Sbjct: 433 CNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQ 492

Query: 620 MDQFMQQ 626
            +QF  Q
Sbjct: 493 CNQFTGQ 499



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 9/68 (13%)

Query: 138 KCDCDPAGIAGPCDAGR----CVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCF 188
           +C   P   AGP  A +    CVC+    G  C+RC   Y N      +G +   C +C 
Sbjct: 258 RCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCD 317

Query: 189 CYGHSASC 196
           C GHS +C
Sbjct: 318 CNGHSETC 325


>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 1823

 Score =  132 bits (332), Expect = 2e-30
 Identities = 153/648 (23%), Positives = 263/648 (40%), Gaps = 97/648 (14%)

Query: 411  GTCIPCNCQGGG-ACDPDTGDCYSGDENPDIE-CADCPIGFYNDP--HDPRSCKPCPCH- 465
            G C+PC+C G    C   +G C     N   E C  C  G+  D     P+ C+PCPC  
Sbjct: 77   GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136

Query: 466  ---NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN 522
                 F+ S   +   V C  C     G  CE CA GY+G+P         C+ C C+ N
Sbjct: 137  PHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLIGST---CKKCDCSGN 192

Query: 523  VDPSAS-GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581
             DP+    +CD +TG+C  C+ NT G  C++C  GY+GD      A  C  CNC   G  
Sbjct: 193  SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGD---ARIAKNCAVCNC---GGG 246

Query: 582  PVGCRS-DGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFMQQLQ---RMEALISKA 637
            P  C S  G C+ + GF  P        CP       I  D+ +  L    R+ AL S  
Sbjct: 247  P--CDSVTGECL-EEGFEPPT----GMDCPT------ISCDKCVWDLTDALRLAAL-SIE 292

Query: 638  QGGDGVVPDTELEGRMQQAEQALQDI-LRDAQISEGASRSLGLQLAKVRSQENSYQSRLD 696
            +G  GV+  +      +   +    I L   ++SE       L+  ++ + EN+ +S L 
Sbjct: 293  EGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSE-RENQYALRKIQINNAENTMKSLLS 351

Query: 697  DLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKS 756
            D++  VE+                           E++AS                    
Sbjct: 352  DVEELVEK---------------------------ENQAS-------------------- 364

Query: 757  LAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGL 816
              ++   + +  +++ ++  QL  +  D   +   +  K L+ G        + +    L
Sbjct: 365  --RKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVL 422

Query: 817  VEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQV--EEAKRI 874
             +K+ +     Q    +    + EAD +Y+  L   +S  RL   +   F V  E+    
Sbjct: 423  AQKMLEEIRSRQPFFTQRELVDEEADEAYE-LLSQAESWQRLHNETRTLFPVVLEQLDDY 481

Query: 875  KQKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRA 934
              K   L   + + ++ + R  +++ N    A+Q  ++ +  +E+  + +   N++ S +
Sbjct: 482  NAKLSDLQEALDQALN-YVRDAEDM-NRATAARQ--RDHEKQQERVREQMEVVNMSLSTS 537

Query: 935  QEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQK-VSDASDKTQQA 993
             ++L+    T  E++ I+KN      ++D  K+E +  +  LS +S   V +A D  Q  
Sbjct: 538  ADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDL 597

Query: 994  ERALGSAAADAQRA-KNGAGEALEISSEIEQEIGSLNLEANVTADGAL 1040
            ++     +     +  NG  +    +S + + I +   EAN TA+ AL
Sbjct: 598  QQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFAL 645



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 62/182 (34%), Positives = 82/182 (45%), Gaps = 36/182 (19%)

Query: 28  CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR---CLPC 84
           CDCNG S +C+         G+G+ C++C  NT G HCEKC +G+     R     C PC
Sbjct: 82  CDCNGNSNECL--------DGSGY-CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPC 132

Query: 85  NC-----NSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH---MLTDAGCTQDQRLLD 136
            C      +      R + + RC C     G  C+RC PG++   +L  + C        
Sbjct: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC-------- 184

Query: 137 SKCDC----DPAGIAGPCD--AGRC-VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
            KCDC    DP  I   CD   G+C  C    TG +C+RC  GYY  D    + C  C C
Sbjct: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNC 243

Query: 190 YG 191
            G
Sbjct: 244 GG 245



 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 49/140 (35%), Positives = 63/140 (45%), Gaps = 23/140 (16%)

Query: 66  EKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRC-SCKPGVTGARCDRCLPGFHMLT 124
           EKC  GF+ H     C+PC+CN  G+ +   D SG C  C+   TG  C++CL G+   +
Sbjct: 65  EKCNAGFF-HTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121

Query: 125 DAGCTQDQRLLDSKCDC---DPAGIAGPC----DAGRCVCKPAVTGERCDRCRSGYYNLD 177
             G  Q        C C     A  A  C     A RC+C     G  C+RC  GYY   
Sbjct: 122 IRGAPQ----FCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY--- 174

Query: 178 GGNP----EGCTQCFCYGHS 193
            GNP      C +C C G+S
Sbjct: 175 -GNPLLIGSTCKKCDCSGNS 193



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 41/145 (28%), Positives = 52/145 (35%), Gaps = 30/145 (20%)

Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG-------ACDPDTGDCYS 433
           +CIC   Y G  C+ CA GY  +   +G   TC  C+C G          CD  TG C +
Sbjct: 154 RCICNENYAGPNCERCAPGYYGNPLLIG--STCKKCDCSGNSDPNLIFEDCDEVTGQCRN 211

Query: 434 GDEN-PDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGAR 492
              N    +C  C  G+Y D    ++C  C C  G   SV  E                 
Sbjct: 212 CLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGE----------------- 254

Query: 493 CELCADGYFGDPFGEHGPVRPCQPC 517
              C +  F  P G   P   C  C
Sbjct: 255 ---CLEEGFEPPTGMDCPTISCDKC 276



 Score = 31.2 bits (69), Expect = 5.7
 Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 7/65 (10%)

Query: 167 DRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQD----VDGWKAVQ 222
           ++C +G+++   G    C  C C G+S  C   + Y VH   +T  +     +DG+    
Sbjct: 65  EKCNAGFFHTLSGE---CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121

Query: 223 RNGSP 227
             G+P
Sbjct: 122 IRGAP 126


>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
          Length = 1816

 Score =  129 bits (325), Expect = 1e-29
 Identities = 150/645 (23%), Positives = 259/645 (40%), Gaps = 98/645 (15%)

Query: 411  GTCIPCNCQGGG-ACDPDTGDCYSGDENPDIE-CADCPIGFYNDP--HDPRSCKPCPCH- 465
            G C+PC+C G    C   +G C     N   E C  C  G+  D     P+ C+PCPC  
Sbjct: 77   GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136

Query: 466  ---NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN 522
                 F+ S   +   V C  C     G  CE CA GY+G+P         C+ C C+ N
Sbjct: 137  PHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLIGST---CKKCDCSGN 192

Query: 523  VDPSAS-GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581
             DP+    +CD +TG+C  C+ NT G  C++C  GY+GD      A  C  CNC   G  
Sbjct: 193  SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGD---ARIAKNCAVCNC---GGG 246

Query: 582  PVGCRS-DGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGG 640
            P  C S  G C+ + GF  P        C  C           +    R+ AL S  +G 
Sbjct: 247  P--CDSVTGECL-EEGFEPPT------GCDKCVWD--------LTDALRLAAL-SIEEGK 288

Query: 641  DGVVPDTELEGRMQQAEQALQDI-LRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLK 699
             GV+  +      +   +    I L   ++SE       L+  ++ + EN+ +S L D++
Sbjct: 289  SGVLSVSSGAAAHRHVNEINATIYLLKTKLSE-RENQYALRKIQINNAENTMKSLLSDVE 347

Query: 700  MTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQ 759
              VE+                           E++AS                      +
Sbjct: 348  ELVEK---------------------------ENQAS----------------------R 358

Query: 760  EATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEK 819
            +   + +  +++ ++  QL  +  D   +   +  K L+ G        + +    L +K
Sbjct: 359  KGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQK 418

Query: 820  LEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQV--EEAKRIKQK 877
            + +     Q    +    + EAD +Y+  L   +S  RL   +   F V  E+      K
Sbjct: 419  MLEEIRSRQPFFTQRELVDEEADEAYE-LLSQAESWQRLHNETRTLFPVVLEQLDDYNAK 477

Query: 878  ADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEA 937
               L   + + ++ + R  +++ N    A+Q  ++ +  +E+  + +   N++ S + ++
Sbjct: 478  LSDLQEALDQALN-YVRDAEDM-NRATAARQ--RDHEKQQERVREQMEVVNMSLSTSADS 533

Query: 938  LSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQK-VSDASDKTQQAERA 996
            L+    T  E++ I+KN      ++D  K+E +  +  LS +S   V +A D  Q  ++ 
Sbjct: 534  LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 593

Query: 997  LGSAAADAQRA-KNGAGEALEISSEIEQEIGSLNLEANVTADGAL 1040
                +     +  NG  +    +S + + I +   EAN TA+ AL
Sbjct: 594  ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFAL 638



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 62/182 (34%), Positives = 82/182 (45%), Gaps = 36/182 (19%)

Query: 28  CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR---CLPC 84
           CDCNG S +C+         G+G+ C++C  NT G HCEKC +G+     R     C PC
Sbjct: 82  CDCNGNSNECL--------DGSGY-CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPC 132

Query: 85  NC-----NSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH---MLTDAGCTQDQRLLD 136
            C      +      R + + RC C     G  C+RC PG++   +L  + C        
Sbjct: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC-------- 184

Query: 137 SKCDC----DPAGIAGPCD--AGRC-VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
            KCDC    DP  I   CD   G+C  C    TG +C+RC  GYY  D    + C  C C
Sbjct: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNC 243

Query: 190 YG 191
            G
Sbjct: 244 GG 245



 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 49/140 (35%), Positives = 63/140 (45%), Gaps = 23/140 (16%)

Query: 66  EKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRC-SCKPGVTGARCDRCLPGFHMLT 124
           EKC  GF+ H     C+PC+CN  G+ +   D SG C  C+   TG  C++CL G+   +
Sbjct: 65  EKCNAGFF-HTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121

Query: 125 DAGCTQDQRLLDSKCDC---DPAGIAGPC----DAGRCVCKPAVTGERCDRCRSGYYNLD 177
             G  Q        C C     A  A  C     A RC+C     G  C+RC  GYY   
Sbjct: 122 IRGAPQ----FCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY--- 174

Query: 178 GGNP----EGCTQCFCYGHS 193
            GNP      C +C C G+S
Sbjct: 175 -GNPLLIGSTCKKCDCSGNS 193



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 39/125 (31%), Positives = 51/125 (40%), Gaps = 16/125 (12%)

Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG-------ACDPDTGDCYS 433
           +CIC   Y G  C+ CA GY  +   +G   TC  C+C G          CD  TG C +
Sbjct: 154 RCICNENYAGPNCERCAPGYYGNPLLIG--STCKKCDCSGNSDPNLIFEDCDEVTGQCRN 211

Query: 434 GDEN-PDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEE------VVCNNCPP 486
              N    +C  C  G+Y D    ++C  C C  G   SV  E  E        C+ C  
Sbjct: 212 CLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVW 271

Query: 487 GVTGA 491
            +T A
Sbjct: 272 DLTDA 276



 Score = 31.2 bits (69), Expect = 5.7
 Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 7/65 (10%)

Query: 167 DRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQD----VDGWKAVQ 222
           ++C +G+++   G    C  C C G+S  C   + Y VH   +T  +     +DG+    
Sbjct: 65  EKCNAGFFHTLSGE---CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121

Query: 223 RNGSP 227
             G+P
Sbjct: 122 IRGAP 126


>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
          Length = 1816

 Score =  129 bits (325), Expect = 1e-29
 Identities = 150/645 (23%), Positives = 259/645 (40%), Gaps = 98/645 (15%)

Query: 411  GTCIPCNCQGGG-ACDPDTGDCYSGDENPDIE-CADCPIGFYNDP--HDPRSCKPCPCH- 465
            G C+PC+C G    C   +G C     N   E C  C  G+  D     P+ C+PCPC  
Sbjct: 77   GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136

Query: 466  ---NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN 522
                 F+ S   +   V C  C     G  CE CA GY+G+P         C+ C C+ N
Sbjct: 137  PHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLIGST---CKKCDCSGN 192

Query: 523  VDPSAS-GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581
             DP+    +CD +TG+C  C+ NT G  C++C  GY+GD      A  C  CNC   G  
Sbjct: 193  SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGD---ARIAKNCAVCNC---GGG 246

Query: 582  PVGCRS-DGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGG 640
            P  C S  G C+ + GF  P        C  C           +    R+ AL S  +G 
Sbjct: 247  P--CDSVTGECL-EEGFEPPT------GCDKCVWD--------LTDALRLAAL-SIEEGK 288

Query: 641  DGVVPDTELEGRMQQAEQALQDI-LRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLK 699
             GV+  +      +   +    I L   ++SE       L+  ++ + EN+ +S L D++
Sbjct: 289  SGVLSVSSGAAAHRHVNEINATIYLLKTKLSE-RENQYALRKIQINNAENTMKSLLSDVE 347

Query: 700  MTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQ 759
              VE+                           E++AS                      +
Sbjct: 348  ELVEK---------------------------ENQAS----------------------R 358

Query: 760  EATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEK 819
            +   + +  +++ ++  QL  +  D   +   +  K L+ G        + +    L +K
Sbjct: 359  KGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQK 418

Query: 820  LEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQV--EEAKRIKQK 877
            + +     Q    +    + EAD +Y+  L   +S  RL   +   F V  E+      K
Sbjct: 419  MLEEIRSRQPFFTQRELVDEEADEAYE-LLSQAESWQRLHNETRTLFPVVLEQLDDYNAK 477

Query: 878  ADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEA 937
               L   + + ++ + R  +++ N    A+Q  ++ +  +E+  + +   N++ S + ++
Sbjct: 478  LSDLQEALDQALN-YVRDAEDM-NRATAARQ--RDHEKQQERVREQMEVVNMSLSTSADS 533

Query: 938  LSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQK-VSDASDKTQQAERA 996
            L+    T  E++ I+KN      ++D  K+E +  +  LS +S   V +A D  Q  ++ 
Sbjct: 534  LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 593

Query: 997  LGSAAADAQRA-KNGAGEALEISSEIEQEIGSLNLEANVTADGAL 1040
                +     +  NG  +    +S + + I +   EAN TA+ AL
Sbjct: 594  ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFAL 638



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 62/182 (34%), Positives = 82/182 (45%), Gaps = 36/182 (19%)

Query: 28  CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR---CLPC 84
           CDCNG S +C+         G+G+ C++C  NT G HCEKC +G+     R     C PC
Sbjct: 82  CDCNGNSNECL--------DGSGY-CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPC 132

Query: 85  NC-----NSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH---MLTDAGCTQDQRLLD 136
            C      +      R + + RC C     G  C+RC PG++   +L  + C        
Sbjct: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC-------- 184

Query: 137 SKCDC----DPAGIAGPCD--AGRC-VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
            KCDC    DP  I   CD   G+C  C    TG +C+RC  GYY  D    + C  C C
Sbjct: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNC 243

Query: 190 YG 191
            G
Sbjct: 244 GG 245



 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 49/140 (35%), Positives = 63/140 (45%), Gaps = 23/140 (16%)

Query: 66  EKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRC-SCKPGVTGARCDRCLPGFHMLT 124
           EKC  GF+ H     C+PC+CN  G+ +   D SG C  C+   TG  C++CL G+   +
Sbjct: 65  EKCNAGFF-HTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121

Query: 125 DAGCTQDQRLLDSKCDC---DPAGIAGPC----DAGRCVCKPAVTGERCDRCRSGYYNLD 177
             G  Q        C C     A  A  C     A RC+C     G  C+RC  GYY   
Sbjct: 122 IRGAPQ----FCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY--- 174

Query: 178 GGNP----EGCTQCFCYGHS 193
            GNP      C +C C G+S
Sbjct: 175 -GNPLLIGSTCKKCDCSGNS 193



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 39/125 (31%), Positives = 51/125 (40%), Gaps = 16/125 (12%)

Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG-------ACDPDTGDCYS 433
           +CIC   Y G  C+ CA GY  +   +G   TC  C+C G          CD  TG C +
Sbjct: 154 RCICNENYAGPNCERCAPGYYGNPLLIG--STCKKCDCSGNSDPNLIFEDCDEVTGQCRN 211

Query: 434 GDEN-PDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEE------VVCNNCPP 486
              N    +C  C  G+Y D    ++C  C C  G   SV  E  E        C+ C  
Sbjct: 212 CLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVW 271

Query: 487 GVTGA 491
            +T A
Sbjct: 272 DLTDA 276



 Score = 31.2 bits (69), Expect = 5.7
 Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 7/65 (10%)

Query: 167 DRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQD----VDGWKAVQ 222
           ++C +G+++   G    C  C C G+S  C   + Y VH   +T  +     +DG+    
Sbjct: 65  EKCNAGFFHTLSGE---CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121

Query: 223 RNGSP 227
             G+P
Sbjct: 122 IRGAP 126


>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
          Length = 1668

 Score =  124 bits (311), Expect = 5e-28
 Identities = 136/569 (23%), Positives = 223/569 (39%), Gaps = 93/569 (16%)

Query: 394 QDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPDIE-CADCPIGFY- 450
           Q C+ GY RD   L   G C+PCNC G    C   +G C +   N   E C  C  G+Y 
Sbjct: 57  QGCSPGYYRDHKGLYT-GRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYG 115

Query: 451 NDPHDPRSCKPCPCH--NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEH 508
           N  H   SC+ CPC   N F+   +    +V C+ C  G TG +CE CA GYFG+P    
Sbjct: 116 NAVHG--SCRACPCPHTNSFATGCVVNGGDVRCS-CKAGYTGTQCERCAPGYFGNPQKFG 172

Query: 509 GPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPAD 568
           G    CQPC CN+N      G+C  LTG C+                    +P   +PA+
Sbjct: 173 G---SCQPCSCNSN---GQLGSCHPLTGDCIN------------------QEPKDSSPAE 208

Query: 569 KCRAC-NCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAF-SCPACYNQVKIQMDQFMQQ 626
           +C  C +C       +    +   + K    G +   G          Q K   +Q +  
Sbjct: 209 ECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNY 268

Query: 627 LQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRS 686
              +    SK +G         LE  +    Q  + +   AQ++   +++L   + +   
Sbjct: 269 RSAISNHGSKIEG---------LERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQ 319

Query: 687 QENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNI---P 743
                  ++ ++   V  +  + +  +    + + L   ++ SL E EA L +       
Sbjct: 320 SAKELDVKIKNVIRNVHMLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQE 379

Query: 744 ASDHYVGPNGFKSLAQEATRLAESHVESASNMEQ----------------------LTRE 781
           A+      NG     + A    +  V+  ++++                       + + 
Sbjct: 380 AAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKS 439

Query: 782 TEDYSKQALSL--VRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTR------- 832
            ++Y K A SL   R+ L + V   S S   A    LVE+ EK     Q+L +       
Sbjct: 440 QKEYEKLAASLNEARQELSDKVRELSRS---AGKTSLVEEAEKHARSLQELAKQLEEIKR 496

Query: 833 -----EATQAEIEADRSYQHSLRLL----DSVSRLQGVSDQSFQVEEAKRIKQKADSLSS 883
                E  +  ++A  +Y++ L  +    D+ +R    S+ + Q    + + +KA +LSS
Sbjct: 497 NASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSS 556

Query: 884 LVTRHMDEFKRTQKNLGNWKEEAQQLLQN 912
              + ++E K TQK L   K+E    L N
Sbjct: 557 NSDKLLNEAKMTQKKL---KQEVSPALNN 582



 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 22/158 (13%)

Query: 22  TSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRC 81
           T R   C+CNG S QC        Q G+G  C+NC  NT G HCE+C+ G+Y +     C
Sbjct: 72  TGRCVPCNCNGHSNQC--------QDGSGI-CVNCQHNTAGEHCERCQEGYYGNAVHGSC 122

Query: 82  LPCNCNSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSK 138
             C C    S +  C  +G   RCSCK G TG +C+RC PG+      G  Q        
Sbjct: 123 RACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF-----GNPQKFGGSCQP 177

Query: 139 CDCDPAGIAGPCD--AGRCV---CKPAVTGERCDRCRS 171
           C C+  G  G C    G C+    K +   E CD C S
Sbjct: 178 CSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 48/145 (33%), Positives = 62/145 (42%), Gaps = 30/145 (20%)

Query: 68  CKNGFYRHRE---RDRCLPCNCNSKGSLSARC-DNSGRC-SCKPGVTGARCDRCLPGFHM 122
           C  G+YR  +     RC+PCNCN     S +C D SG C +C+    G  C+RC  G++ 
Sbjct: 59  CSPGYYRDHKGLYTGRCVPCNCNGH---SNQCQDGSGICVNCQHNTAGEHCERCQEGYYG 115

Query: 123 LTDAGCTQDQRLLDSKCDCDPAG-IAGPCDAG----RCVCKPAVTGERCDRCRSGYYNLD 177
               G  +        C C      A  C       RC CK   TG +C+RC  GY+   
Sbjct: 116 NAVHGSCR-------ACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF--- 165

Query: 178 GGNPE----GCTQCFC--YGHSASC 196
            GNP+     C  C C   G   SC
Sbjct: 166 -GNPQKFGGSCQPCSCNSNGQLGSC 189



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 29/71 (40%), Positives = 38/71 (53%), Gaps = 8/71 (11%)

Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG---GACDPDTGDCYS---G 434
           +C C  GY G  C+ CA GY  +  + G  G+C PC+C      G+C P TGDC +    
Sbjct: 145 RCSCKAGYTGTQCERCAPGYFGNPQKFG--GSCQPCSCNSNGQLGSCHPLTGDCINQEPK 202

Query: 435 DENPDIECADC 445
           D +P  EC DC
Sbjct: 203 DSSPAEECDDC 213



 Score = 37.7 bits (86), Expect = 0.061
 Identities = 49/256 (19%), Positives = 103/256 (40%), Gaps = 40/256 (15%)

Query: 856  SRLQGVSDQSFQVEEAKRIKQKADSLS-------SLVTRHMDEFKRTQKNLGNWKEEAQQ 908
            S+LQG+S  +  +E+ + ++ +A  L        S ++ H  + +  ++ L +  +E + 
Sbjct: 236  SQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFET 295

Query: 909  LLQNGKSGREKSDQLLSRANLAKSRAQEA----------LSMGNA--TFYEVE------- 949
            L +  +    K+  L +  N A   A+E           + M N   T+ +         
Sbjct: 296  LQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHMLNRIRTWQKTHQGENNGL 355

Query: 950  --SILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRA 1007
              SI  +L E++ ++ + +A  +EA       + +   A+   Q+ ERALG+     +  
Sbjct: 356  ANSIRDSLNEYEAKLSDLRARLQEA-------AAQAKQANGLNQENERALGAIQRQVKEI 408

Query: 1008 KNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEF 1067
             +   +  +  +  +  +    L+ N+        +K    L + + E   EL  K  E 
Sbjct: 409  NSLQSDFTKYLTTADSSL----LQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVREL 464

Query: 1068 DTNMDAVQMVITEAQK 1083
              +     +V  EA+K
Sbjct: 465  SRSAGKTSLV-EEAEK 479


>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
          Length = 639

 Score =  120 bits (302), Expect = 5e-27
 Identities = 64/186 (34%), Positives = 83/186 (44%), Gaps = 18/186 (9%)

Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA-CDPDTGDCYSGDENPD 439
           +C C VG  G  C  C  GY   S        C+PC C    A CD  TG C +  EN  
Sbjct: 308 KCQCKVGVIGSICDRCQDGYYGFSKN-----GCLPCQCNNRSASCDALTGACLNCQENSK 362

Query: 440 -IECADCPIGFYNDPHDPRSCKPCPCH---NGFSCSVMPETEEVVCNNCPPGVTGARCEL 495
              C +C  GFY  P   + C  CPC    +  SCS+     E  C+ C  G  G  C  
Sbjct: 363 GNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNK 422

Query: 496 CADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGN-CDRLTGRCLKCIHNTAGIYCDQCK 554
           C +GY+            C+ CQC+ +VDP  +   C   +G C+ C+HNT G +C+ C 
Sbjct: 423 CENGYYNFD-------SICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCL 475

Query: 555 AGYFGD 560
            GY  D
Sbjct: 476 EGYVHD 481



 Score =  110 bits (276), Expect = 6e-24
 Identities = 68/204 (33%), Positives = 95/204 (46%), Gaps = 41/204 (20%)

Query: 416 CNCQGGGA-----CDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSC 470
           CNC   G+     C+  TG C        + C  C  GFY + +    C+PC C    + 
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLN-YTSGLCQPCDCSPHGAL 299

Query: 471 SVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGN 530
           S+ P      C  C  GV G+ C+ C DGY+G  F ++G    C PCQCNN      S +
Sbjct: 300 SI-PCNSSGKCQ-CKVGVIGSICDRCQDGYYG--FSKNG----CLPCQCNNR-----SAS 346

Query: 531 CDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGT 590
           CD LTG CL C  N+ G +C++CK G++    +P+   +C  C C+ +        S G+
Sbjct: 347 CDALTGACLNCQENSKGNHCEECKEGFY---QSPDATKECLRCPCSAV-------TSTGS 396

Query: 591 C------------VCKPGFGGPNC 602
           C             CK G+ GPNC
Sbjct: 397 CSIKSSELEPECDQCKDGYIGPNC 420



 Score =  106 bits (264), Expect = 1e-22
 Identities = 64/205 (31%), Positives = 92/205 (44%), Gaps = 33/205 (16%)

Query: 1   MPALWLGCCLCFSLL-------------LPAARATSRREVCDCNGKSRQCIFDRELHRQT 47
           MP  +LG   C S L             L  + A     VC+C+      +    ++R  
Sbjct: 201 MPQKYLGKYACESNLKSKYLPLTQPVMNLRVSEAVKTEYVCNCS-----VVGSLNVNRCN 255

Query: 48  GNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPG 107
               +C  C     G+HCE CK GFY +     C PC+C+  G+LS  C++SG+C CK G
Sbjct: 256 QTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKVG 314

Query: 108 VTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDA--GRCV-CKPAVTGE 164
           V G+ CDRC  G++  +  GC          C C+    +  CDA  G C+ C+    G 
Sbjct: 315 VIGSICDRCQDGYYGFSKNGCL--------PCQCN--NRSASCDALTGACLNCQENSKGN 364

Query: 165 RCDRCRSGYYNLDGGNPEGCTQCFC 189
            C+ C+ G+Y       E C +C C
Sbjct: 365 HCEECKEGFYQSPDATKE-CLRCPC 388



 Score = 95.1 bits (235), Expect = 3e-19
 Identities = 49/117 (41%), Positives = 66/117 (56%), Gaps = 14/117 (11%)

Query: 84  CNCNSKGSLSA-RCDNS-GRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDC 141
           CNC+  GSL+  RC+ + G+C C+PG  G  C+ C  GF++   +G  Q        CDC
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQP-------CDC 293

Query: 142 DPAG-IAGPCDA-GRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASC 196
            P G ++ PC++ G+C CK  V G  CDRC+ GYY   G +  GC  C C   SASC
Sbjct: 294 SPHGALSIPCNSSGKCQCKVGVIGSICDRCQDGYY---GFSKNGCLPCQCNNRSASC 347



 Score = 80.5 bits (197), Expect = 8e-15
 Identities = 60/181 (33%), Positives = 81/181 (44%), Gaps = 41/181 (22%)

Query: 28  CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR-CLPCNC 86
           C CN +S  C         TG    CLNC +N+ G HCE+CK GFY+  +  + CL C C
Sbjct: 338 CQCNNRSASC------DALTG---ACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPC 388

Query: 87  N---SKGSLSARCDN-SGRCS-CKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDC 141
           +   S GS S +       C  CK G  G  C++C  G++   D+ C         KC C
Sbjct: 389 SAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNF-DSICR--------KCQC 439

Query: 142 ----DPAGIAGPC--DAGRCV-CKPAVTGERCDRCRSGY-YNLDGG---------NPEGC 184
               DP      C  ++G C+ C    TG  C+ C  GY ++L+G           PEG 
Sbjct: 440 HGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEGNCIKKEVILPTPEGS 499

Query: 185 T 185
           T
Sbjct: 500 T 500



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 6/86 (6%)

Query: 519 CNNNVDPSASGN-CDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNP 577
           CN +V  S + N C++ TG+C +C     G++C+ CK G++ +      +  C+ C+C+P
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLN----YTSGLCQPCDCSP 295

Query: 578 MGSEPVGCRSDGTCVCKPGFGGPNCE 603
            G+  + C S G C CK G  G  C+
Sbjct: 296 HGALSIPCNSSGKCQCKVGVIGSICD 321


>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
          Length = 1724

 Score =  114 bits (286), Expect = 4e-25
 Identities = 169/721 (23%), Positives = 290/721 (40%), Gaps = 129/721 (17%)

Query: 394  QDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPDIE-CADCPIGFY- 450
            Q C+ GY RD   L   G C+PCNC G    C   +G C +   N   E C  C  G+Y 
Sbjct: 57   QGCSPGYYRDHKGLYT-GRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYG 115

Query: 451  NDPHDPRSCKPCPCH--NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEH 508
            N  H   SC+ CPC   N F+   +    +V C+ C  G TG +CE CA GYFG+P    
Sbjct: 116  NAVHG--SCRACPCPHTNSFATGCVVNGGDVRCS-CKAGYTGTQCERCAPGYFGNPQKFG 172

Query: 509  GPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPAD 568
            G    CQPC CN+N      G+C  LTG C+                    +P   +PA+
Sbjct: 173  G---SCQPCSCNSN---GQLGSCHPLTGDCIN------------------QEPKDSSPAE 208

Query: 569  KCRAC-NCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAF-SCPACYNQVKIQMDQFMQQ 626
            +C  C +C       +    +   + K    G +   G          Q K   +Q +  
Sbjct: 209  ECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNY 268

Query: 627  LQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRS 686
               +    SK +G         LE  +    Q  + +   AQ++   +++L         
Sbjct: 269  RSAISNHGSKIEG---------LERELTDLNQEFETLQEKAQVNSRKAQTLN-------- 311

Query: 687  QENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASD 746
                     +++    +  + L  + +N +R+ H L+ Q+  +  E     GN N+P+ D
Sbjct: 312  ---------NNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGE-----GN-NVPSGD 356

Query: 747  HYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRK-----ALHEGV 801
                   F     EA R+         N  +  RE E   +++  L+ +       H+G 
Sbjct: 357  -------FSREWAEAQRMMRE--LRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGE 407

Query: 802  GSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGV 861
             +G  +   ++   L E   K   L  +L   A QA+ +A+   Q + R L ++ R Q  
Sbjct: 408  NNGLAN---SIRDSLNEYEAKLSDLRARLQEAAAQAK-QANGLNQENERALGAIQR-QVK 462

Query: 862  SDQSFQVEEAKRIKQKADSL--SSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREK 919
               S Q +  K +     SL  +++  + M++ ++  + L     EA+Q         E 
Sbjct: 463  EINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQ---------EL 513

Query: 920  SDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVD--NRKAEAEEAMKRLS 977
            SD++     L++S  + +L        E E   ++L+E   Q++   R A  +E ++   
Sbjct: 514  SDKV---RELSRSAGKTSL------VEEAEKHARSLQELAKQLEEIKRNASGDELVR--- 561

Query: 978  YISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALE--ISSEIEQEIGSLNLEANVT 1035
                   DA+   +    A+ +A   A RA + +  AL+  I  ++ ++  +L+  ++  
Sbjct: 562  ----CAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKL 617

Query: 1036 ADGALAMEKGLASLKSEMREVEGELE--------RKELEFDTNMDAVQMVITEAQKVDTR 1087
             + A   +K    LK E+      L+        +KE+  DTN+  ++  +   Q+ D  
Sbjct: 618  LNEAKMTQK---KLKQEVSPALNNLQQTLNIVTVQKEV-IDTNLTTLRDGLHGIQRGDID 673

Query: 1088 A 1088
            A
Sbjct: 674  A 674



 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 22/158 (13%)

Query: 22  TSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRC 81
           T R   C+CNG S QC        Q G+G  C+NC  NT G HCE+C+ G+Y +     C
Sbjct: 72  TGRCVPCNCNGHSNQC--------QDGSGI-CVNCQHNTAGEHCERCQEGYYGNAVHGSC 122

Query: 82  LPCNCNSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSK 138
             C C    S +  C  +G   RCSCK G TG +C+RC PG+      G  Q        
Sbjct: 123 RACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF-----GNPQKFGGSCQP 177

Query: 139 CDCDPAGIAGPCD--AGRCV---CKPAVTGERCDRCRS 171
           C C+  G  G C    G C+    K +   E CD C S
Sbjct: 178 CSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 48/145 (33%), Positives = 62/145 (42%), Gaps = 30/145 (20%)

Query: 68  CKNGFYRHRE---RDRCLPCNCNSKGSLSARC-DNSGRC-SCKPGVTGARCDRCLPGFHM 122
           C  G+YR  +     RC+PCNCN     S +C D SG C +C+    G  C+RC  G++ 
Sbjct: 59  CSPGYYRDHKGLYTGRCVPCNCNGH---SNQCQDGSGICVNCQHNTAGEHCERCQEGYYG 115

Query: 123 LTDAGCTQDQRLLDSKCDCDPAG-IAGPCDAG----RCVCKPAVTGERCDRCRSGYYNLD 177
               G  +        C C      A  C       RC CK   TG +C+RC  GY+   
Sbjct: 116 NAVHGSCR-------ACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF--- 165

Query: 178 GGNPE----GCTQCFC--YGHSASC 196
            GNP+     C  C C   G   SC
Sbjct: 166 -GNPQKFGGSCQPCSCNSNGQLGSC 189



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 29/71 (40%), Positives = 38/71 (53%), Gaps = 8/71 (11%)

Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG---GACDPDTGDCYS---G 434
           +C C  GY G  C+ CA GY  +  + G  G+C PC+C      G+C P TGDC +    
Sbjct: 145 RCSCKAGYTGTQCERCAPGYFGNPQKFG--GSCQPCSCNSNGQLGSCHPLTGDCINQEPK 202

Query: 435 DENPDIECADC 445
           D +P  EC DC
Sbjct: 203 DSSPAEECDDC 213


>gi|219842266 usherin isoform B [Homo sapiens]
          Length = 5202

 Score =  105 bits (263), Expect = 2e-22
 Identities = 68/206 (33%), Positives = 96/206 (46%), Gaps = 41/206 (19%)

Query: 28  CDCNGKSRQCIFDREL------HRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR- 80
           C CN  S+ C ++  +      H + G G  C +C  NT G +CE CK+ F+R    D  
Sbjct: 575 CQCNSHSKSCHYNISVDPFPFEHFRGGGGV-CDDCEHNTTGRNCELCKDYFFRQVGADPS 633

Query: 81  ----CLPCNCNSKGSL--SARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQ 130
               C PC+C++ G+   S  CD   G+C+CK  V+G +C++C  GF+ L +    GC  
Sbjct: 634 AIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGC-- 691

Query: 131 DQRLLDSKCDCDPAG-----IAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCT 185
                 S C+C+ +G     I    ++G+C CK  V G RCD C  G+  L   N  GC 
Sbjct: 692 ------SPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCE 745

Query: 186 QC----------FCYGHSASCRSSAE 201
            C          FC  HS  C    E
Sbjct: 746 PCQCNLHGSVNKFCNPHSGQCECKKE 771



 Score =  101 bits (251), Expect = 4e-21
 Identities = 58/150 (38%), Positives = 73/150 (48%), Gaps = 21/150 (14%)

Query: 50  GFRCLNCNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCNSKGSLSARC---DNSGRCSC 104
           G +C NC  +  G  C +C+NGFY  +E D   C PCNCN+ G++        NSG+C C
Sbjct: 659 GGQC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKC 717

Query: 105 KPGVTGARCDRCLPGFHML---TDAGCTQDQRLLDSKCD--CDPAGIAGPCDAGRCVCKP 159
           K  V G RCD C  GF  L    D GC   Q  L    +  C+P        +G+C CK 
Sbjct: 718 KANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNP-------HSGQCECKK 770

Query: 160 AVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
              G +CD CR  +Y LD  N   C  C C
Sbjct: 771 EAKGLQCDTCRENFYGLDVTN---CKACDC 797



 Score =  101 bits (251), Expect = 4e-21
 Identities = 74/240 (30%), Positives = 99/240 (41%), Gaps = 37/240 (15%)

Query: 381  QCICPVGYKGQFCQDCASG--YKRDSARLGPFGTCIPCNCQGGGA------CDPDTGDCY 432
            QCIC    +G+ C  C  G  Y R +        C+PCNC   G       C+  TG C 
Sbjct: 814  QCICKPNVEGRQCNKCLEGNFYLRQNNSF----LCLPCNCDKTGTINGSLLCNKSTGQCP 869

Query: 433  SGDENPDIECADCPIGFYNDPHDP-RSCKPCPCHNGFSCSVMPETEEVVCNN------CP 485
                   + C  C    YN   D  + C+ C C    S   +P T   +C+       C 
Sbjct: 870  CKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECD---SLGTLPGT---ICDPISGQCLCV 923

Query: 486  PGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNT 545
            P   G RC  C  G++  P    G    C PC C+     + +  C+ LTG+C+    + 
Sbjct: 924  PNRQGRRCNQCQPGFYISP----GNATGCLPCSCHTT--GAVNHICNSLTGQCVCQDASI 977

Query: 546  AGIYCDQCKAGYFG-DPLAPNPADKCRACNCNPMGSEPVGCR-SDGTCVCKPGFGGPNCE 603
            AG  CDQCK  YFG DP       +C+ CNC+  G+    C    G C CK    G  C+
Sbjct: 978  AGQRCDQCKDHYFGFDP----QTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCD 1033



 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 71/237 (29%), Positives = 98/237 (41%), Gaps = 34/237 (14%)

Query: 381 QCICPVGYKGQFCQDCASGYK--RDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSG 434
           QC C     G  C  C  G+K  R    +G    C PC C   G+    C+P +G C   
Sbjct: 714 QCKCKANVIGLRCDHCNFGFKFLRSFNDVG----CEPCQCNLHGSVNKFCNPHSGQCECK 769

Query: 435 DENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNN------CPPGV 488
            E   ++C  C   FY    D  +CK C C    S   +P T   VCN       C P V
Sbjct: 770 KEAKGLQCDTCRENFYG--LDVTNCKACDCDTAGS---LPGT---VCNAKTGQCICKPNV 821

Query: 489 TGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGI 548
            G +C  C +G F   +        C PC C+     + S  C++ TG+C  C     G+
Sbjct: 822 EGRQCNKCLEGNF---YLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC-PCKLGVTGL 877

Query: 549 YCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD---GTCVCKPGFGGPNC 602
            C+QC+   +   L  +    C+ C C+ +G+ P G   D   G C+C P   G  C
Sbjct: 878 RCNQCEPHRYN--LTIDNFQHCQMCECDSLGTLP-GTICDPISGQCLCVPNRQGRRC 931



 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 63/218 (28%), Positives = 94/218 (43%), Gaps = 30/218 (13%)

Query: 416 CNCQG-GGACDPDTGD----CYSGDENPDIECADCPIGFYNDPHDPR-------SCKPCP 463
           C C G    CD  +      C        + C  C +  YND    +       +CKPC 
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRC-LPLYNDKPFRQGDQVYAFNCKPCQ 576

Query: 464 CHNG-----FSCSVMPETEEV------VCNNCPPGVTGARCELCADGYFGDPFGEHGPVR 512
           C++      ++ SV P   E       VC++C    TG  CELC D +F     +   + 
Sbjct: 577 CNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAID 636

Query: 513 PCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRA 572
            C+PC C+     + S  CD++ G+C  C  + +G  C+QC+ G++   L     D C  
Sbjct: 637 VCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYN--LQELDPDGCSP 693

Query: 573 CNCNPMGS--EPVGC-RSDGTCVCKPGFGGPNCEHGAF 607
           CNCN  G+    + C ++ G C CK    G  C+H  F
Sbjct: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNF 731



 Score = 89.4 bits (220), Expect = 2e-17
 Identities = 48/141 (34%), Positives = 66/141 (46%), Gaps = 13/141 (9%)

Query: 56  CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNS--GRCSCKPGVTGARC 113
           C     G+ C+ C+  FY   +   C  C+C++ GSL     N+  G+C CKP V G +C
Sbjct: 768 CKKEAKGLQCDTCRENFYG-LDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQC 826

Query: 114 DRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPC-----DAGRCVCKPAVTGERCDR 168
           ++CL G   L      Q+   L   C+CD  G            G+C CK  VTG RC++
Sbjct: 827 NKCLEGNFYLR-----QNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQ 881

Query: 169 CRSGYYNLDGGNPEGCTQCFC 189
           C    YNL   N + C  C C
Sbjct: 882 CEPHRYNLTIDNFQHCQMCEC 902



 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 57/183 (31%), Positives = 74/183 (40%), Gaps = 24/183 (13%)

Query: 381  QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-----GGACDPDTGDCYSGD 435
            QC C +G  G  C  C     R +  +  F  C  C C       G  CDP +G C    
Sbjct: 867  QCPCKLGVTGLRCNQCEP--HRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVP 924

Query: 436  ENPDIECADCPIGFYNDPHDPRSCKPCPCHN----GFSCSVMPETEEVVCNNCPPGVTGA 491
                  C  C  GFY  P +   C PC CH        C+ +  T + VC +    + G 
Sbjct: 925  NRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSL--TGQCVCQDA--SIAGQ 980

Query: 492  RCELCADGYFG-DPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYC 550
            RC+ C D YFG DP         CQPC C  ++  + +  C  +TG+C  C     G  C
Sbjct: 981  RCDQCKDHYFGFDP-----QTGRCQPCNC--HLSGALNETCHLVTGQCF-CKQFVTGSKC 1032

Query: 551  DQC 553
            D C
Sbjct: 1033 DAC 1035



 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 69/237 (29%), Positives = 96/237 (40%), Gaps = 33/237 (13%)

Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPD------TGDCYSG 434
           QC C     G+ C  C +G+  +   L P G C PCNC   G  D D      +G C   
Sbjct: 661 QCNCKRHVSGRQCNQCQNGFY-NLQELDPDG-CSPCNCNTSGTVDGDITCHQNSGQCKCK 718

Query: 435 DENPDIECADCPIGF-----YNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVT 489
                + C  C  GF     +ND      C+PC C+   S +         C  C     
Sbjct: 719 ANVIGLRCDHCNFGFKFLRSFNDV----GCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAK 773

Query: 490 GARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGN-CDRLTGRCLKCIHNTAGI 548
           G +C+ C + ++G        V  C+ C C  +   S  G  C+  TG+C+ C  N  G 
Sbjct: 774 GLQCDTCRENFYG------LDVTNCKACDC--DTAGSLPGTVCNAKTGQCI-CKPNVEGR 824

Query: 549 YCDQCKAGYFGDPLAPNPADKCRACNCNPMGS---EPVGCRSDGTCVCKPGFGGPNC 602
            C++C  G F   L  N +  C  CNC+  G+     +  +S G C CK G  G  C
Sbjct: 825 QCNKCLEGNF--YLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRC 879



 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 58/193 (30%), Positives = 84/193 (43%), Gaps = 45/193 (23%)

Query: 28  CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDN-TDGIHCEKCKNGFYRH--RERDR---- 80
           C C+G +  C         T   +RCL   ++ T+G+HC++C   +     R+ D+    
Sbjct: 518 CQCHGHADNC-------DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAF 570

Query: 81  -CLPCNCNSKGSLSARCD---------------NSGRCS-CKPGVTGARCDRCLPGFHML 123
            C PC CNS    S  C                  G C  C+   TG  C+ C   F   
Sbjct: 571 NCKPCQCNSH---SKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQ 627

Query: 124 TDAGCTQDQRLLD--SKCDCDPAGIAGP---CD--AGRCVCKPAVTGERCDRCRSGYYNL 176
             A    D   +D    CDCD  G       CD   G+C CK  V+G +C++C++G+YNL
Sbjct: 628 VGA----DPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNL 683

Query: 177 DGGNPEGCTQCFC 189
              +P+GC+ C C
Sbjct: 684 QELDPDGCSPCNC 696



 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 62/218 (28%), Positives = 89/218 (40%), Gaps = 44/218 (20%)

Query: 8    CCLCFSLLLPAARATSRREVCDCNGKSRQC--IFDRELHRQTGNGFRCLNCN-DNTD--- 61
            C    SL      A + + +C  N + RQC    +   + +  N F CL CN D T    
Sbjct: 797  CDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTIN 856

Query: 62   -------------------GIHCEKCKNGFYRHR--ERDRCLPCNCNSKGSLSAR-CDN- 98
                               G+ C +C+   Y         C  C C+S G+L    CD  
Sbjct: 857  GSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPI 916

Query: 99   SGRCSCKPGVTGARCDRCLPGFHML--TDAGCTQDQRLLDSKCDCDPAGIAGP-CDA--G 153
            SG+C C P   G RC++C PGF++      GC          C C   G     C++  G
Sbjct: 917  SGQCLCVPNRQGRRCNQCQPGFYISPGNATGCL--------PCSCHTTGAVNHICNSLTG 968

Query: 154  RCVCKPA-VTGERCDRCRSGYYNLDGGNPEGCTQCFCY 190
            +CVC+ A + G+RCD+C+  Y+  D      C  C C+
Sbjct: 969  QCVCQDASIAGQRCDQCKDHYFGFDPQTGR-CQPCNCH 1005



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 45/141 (31%), Positives = 69/141 (48%), Gaps = 13/141 (9%)

Query: 52   RCLNCNDNTDGIHCEKCKNGFY-RHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPG-V 108
            +CL C  N  G  C +C+ GFY        CLPC+C++ G+++  C++ +G+C C+   +
Sbjct: 919  QCL-CVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASI 977

Query: 109  TGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGER 165
             G RCD+C   +           Q      C+C  +G     C    G+C CK  VTG +
Sbjct: 978  AGQRCDQCKDHYFGF------DPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSK 1031

Query: 166  CDRCRSGYYNLDGGNPEGCTQ 186
            CD C     +LD  N  GC++
Sbjct: 1032 CDACVPSASHLDVNNLLGCSK 1052



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 24/77 (31%), Positives = 29/77 (37%), Gaps = 13/77 (16%)

Query: 131 DQRLLDSKCDCDPAGIAGPCDAG----RCVCKPA--VTGERCDRCRSGYYNL-----DGG 179
           D+  +  +C C   G A  CD      RC+C       G  CDRC   Y +      D  
Sbjct: 510 DEITISGRCQCH--GHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQV 567

Query: 180 NPEGCTQCFCYGHSASC 196
               C  C C  HS SC
Sbjct: 568 YAFNCKPCQCNSHSKSC 584


>gi|219842259 usherin isoform A [Homo sapiens]
          Length = 1546

 Score =  105 bits (263), Expect = 2e-22
 Identities = 68/206 (33%), Positives = 96/206 (46%), Gaps = 41/206 (19%)

Query: 28  CDCNGKSRQCIFDREL------HRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR- 80
           C CN  S+ C ++  +      H + G G  C +C  NT G +CE CK+ F+R    D  
Sbjct: 575 CQCNSHSKSCHYNISVDPFPFEHFRGGGGV-CDDCEHNTTGRNCELCKDYFFRQVGADPS 633

Query: 81  ----CLPCNCNSKGSL--SARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQ 130
               C PC+C++ G+   S  CD   G+C+CK  V+G +C++C  GF+ L +    GC  
Sbjct: 634 AIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGC-- 691

Query: 131 DQRLLDSKCDCDPAG-----IAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCT 185
                 S C+C+ +G     I    ++G+C CK  V G RCD C  G+  L   N  GC 
Sbjct: 692 ------SPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCE 745

Query: 186 QC----------FCYGHSASCRSSAE 201
            C          FC  HS  C    E
Sbjct: 746 PCQCNLHGSVNKFCNPHSGQCECKKE 771



 Score =  101 bits (251), Expect = 4e-21
 Identities = 58/150 (38%), Positives = 73/150 (48%), Gaps = 21/150 (14%)

Query: 50  GFRCLNCNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCNSKGSLSARC---DNSGRCSC 104
           G +C NC  +  G  C +C+NGFY  +E D   C PCNCN+ G++        NSG+C C
Sbjct: 659 GGQC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKC 717

Query: 105 KPGVTGARCDRCLPGFHML---TDAGCTQDQRLLDSKCD--CDPAGIAGPCDAGRCVCKP 159
           K  V G RCD C  GF  L    D GC   Q  L    +  C+P        +G+C CK 
Sbjct: 718 KANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNP-------HSGQCECKK 770

Query: 160 AVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
              G +CD CR  +Y LD  N   C  C C
Sbjct: 771 EAKGLQCDTCRENFYGLDVTN---CKACDC 797



 Score =  101 bits (251), Expect = 4e-21
 Identities = 74/240 (30%), Positives = 99/240 (41%), Gaps = 37/240 (15%)

Query: 381  QCICPVGYKGQFCQDCASG--YKRDSARLGPFGTCIPCNCQGGGA------CDPDTGDCY 432
            QCIC    +G+ C  C  G  Y R +        C+PCNC   G       C+  TG C 
Sbjct: 814  QCICKPNVEGRQCNKCLEGNFYLRQNNSF----LCLPCNCDKTGTINGSLLCNKSTGQCP 869

Query: 433  SGDENPDIECADCPIGFYNDPHDP-RSCKPCPCHNGFSCSVMPETEEVVCNN------CP 485
                   + C  C    YN   D  + C+ C C    S   +P T   +C+       C 
Sbjct: 870  CKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECD---SLGTLPGT---ICDPISGQCLCV 923

Query: 486  PGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNT 545
            P   G RC  C  G++  P    G    C PC C+     + +  C+ LTG+C+    + 
Sbjct: 924  PNRQGRRCNQCQPGFYISP----GNATGCLPCSCHTT--GAVNHICNSLTGQCVCQDASI 977

Query: 546  AGIYCDQCKAGYFG-DPLAPNPADKCRACNCNPMGSEPVGCR-SDGTCVCKPGFGGPNCE 603
            AG  CDQCK  YFG DP       +C+ CNC+  G+    C    G C CK    G  C+
Sbjct: 978  AGQRCDQCKDHYFGFDP----QTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCD 1033



 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 71/237 (29%), Positives = 98/237 (41%), Gaps = 34/237 (14%)

Query: 381 QCICPVGYKGQFCQDCASGYK--RDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSG 434
           QC C     G  C  C  G+K  R    +G    C PC C   G+    C+P +G C   
Sbjct: 714 QCKCKANVIGLRCDHCNFGFKFLRSFNDVG----CEPCQCNLHGSVNKFCNPHSGQCECK 769

Query: 435 DENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNN------CPPGV 488
            E   ++C  C   FY    D  +CK C C    S   +P T   VCN       C P V
Sbjct: 770 KEAKGLQCDTCRENFYG--LDVTNCKACDCDTAGS---LPGT---VCNAKTGQCICKPNV 821

Query: 489 TGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGI 548
            G +C  C +G F   +        C PC C+     + S  C++ TG+C  C     G+
Sbjct: 822 EGRQCNKCLEGNF---YLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC-PCKLGVTGL 877

Query: 549 YCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD---GTCVCKPGFGGPNC 602
            C+QC+   +   L  +    C+ C C+ +G+ P G   D   G C+C P   G  C
Sbjct: 878 RCNQCEPHRYN--LTIDNFQHCQMCECDSLGTLP-GTICDPISGQCLCVPNRQGRRC 931



 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 63/218 (28%), Positives = 94/218 (43%), Gaps = 30/218 (13%)

Query: 416 CNCQG-GGACDPDTGD----CYSGDENPDIECADCPIGFYNDPHDPR-------SCKPCP 463
           C C G    CD  +      C        + C  C +  YND    +       +CKPC 
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRC-LPLYNDKPFRQGDQVYAFNCKPCQ 576

Query: 464 CHNG-----FSCSVMPETEEV------VCNNCPPGVTGARCELCADGYFGDPFGEHGPVR 512
           C++      ++ SV P   E       VC++C    TG  CELC D +F     +   + 
Sbjct: 577 CNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAID 636

Query: 513 PCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRA 572
            C+PC C+     + S  CD++ G+C  C  + +G  C+QC+ G++   L     D C  
Sbjct: 637 VCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYN--LQELDPDGCSP 693

Query: 573 CNCNPMGS--EPVGC-RSDGTCVCKPGFGGPNCEHGAF 607
           CNCN  G+    + C ++ G C CK    G  C+H  F
Sbjct: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNF 731



 Score = 89.4 bits (220), Expect = 2e-17
 Identities = 48/141 (34%), Positives = 66/141 (46%), Gaps = 13/141 (9%)

Query: 56  CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNS--GRCSCKPGVTGARC 113
           C     G+ C+ C+  FY   +   C  C+C++ GSL     N+  G+C CKP V G +C
Sbjct: 768 CKKEAKGLQCDTCRENFYG-LDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQC 826

Query: 114 DRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPC-----DAGRCVCKPAVTGERCDR 168
           ++CL G   L      Q+   L   C+CD  G            G+C CK  VTG RC++
Sbjct: 827 NKCLEGNFYLR-----QNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQ 881

Query: 169 CRSGYYNLDGGNPEGCTQCFC 189
           C    YNL   N + C  C C
Sbjct: 882 CEPHRYNLTIDNFQHCQMCEC 902



 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 57/183 (31%), Positives = 74/183 (40%), Gaps = 24/183 (13%)

Query: 381  QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-----GGACDPDTGDCYSGD 435
            QC C +G  G  C  C     R +  +  F  C  C C       G  CDP +G C    
Sbjct: 867  QCPCKLGVTGLRCNQCEP--HRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVP 924

Query: 436  ENPDIECADCPIGFYNDPHDPRSCKPCPCHN----GFSCSVMPETEEVVCNNCPPGVTGA 491
                  C  C  GFY  P +   C PC CH        C+ +  T + VC +    + G 
Sbjct: 925  NRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSL--TGQCVCQDA--SIAGQ 980

Query: 492  RCELCADGYFG-DPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYC 550
            RC+ C D YFG DP         CQPC C  ++  + +  C  +TG+C  C     G  C
Sbjct: 981  RCDQCKDHYFGFDP-----QTGRCQPCNC--HLSGALNETCHLVTGQCF-CKQFVTGSKC 1032

Query: 551  DQC 553
            D C
Sbjct: 1033 DAC 1035



 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 69/237 (29%), Positives = 96/237 (40%), Gaps = 33/237 (13%)

Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPD------TGDCYSG 434
           QC C     G+ C  C +G+  +   L P G C PCNC   G  D D      +G C   
Sbjct: 661 QCNCKRHVSGRQCNQCQNGFY-NLQELDPDG-CSPCNCNTSGTVDGDITCHQNSGQCKCK 718

Query: 435 DENPDIECADCPIGF-----YNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVT 489
                + C  C  GF     +ND      C+PC C+   S +         C  C     
Sbjct: 719 ANVIGLRCDHCNFGFKFLRSFNDV----GCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAK 773

Query: 490 GARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGN-CDRLTGRCLKCIHNTAGI 548
           G +C+ C + ++G        V  C+ C C  +   S  G  C+  TG+C+ C  N  G 
Sbjct: 774 GLQCDTCRENFYG------LDVTNCKACDC--DTAGSLPGTVCNAKTGQCI-CKPNVEGR 824

Query: 549 YCDQCKAGYFGDPLAPNPADKCRACNCNPMGS---EPVGCRSDGTCVCKPGFGGPNC 602
            C++C  G F   L  N +  C  CNC+  G+     +  +S G C CK G  G  C
Sbjct: 825 QCNKCLEGNF--YLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRC 879



 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 58/193 (30%), Positives = 84/193 (43%), Gaps = 45/193 (23%)

Query: 28  CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDN-TDGIHCEKCKNGFYRH--RERDR---- 80
           C C+G +  C         T   +RCL   ++ T+G+HC++C   +     R+ D+    
Sbjct: 518 CQCHGHADNC-------DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAF 570

Query: 81  -CLPCNCNSKGSLSARCD---------------NSGRCS-CKPGVTGARCDRCLPGFHML 123
            C PC CNS    S  C                  G C  C+   TG  C+ C   F   
Sbjct: 571 NCKPCQCNSH---SKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQ 627

Query: 124 TDAGCTQDQRLLD--SKCDCDPAGIAGP---CD--AGRCVCKPAVTGERCDRCRSGYYNL 176
             A    D   +D    CDCD  G       CD   G+C CK  V+G +C++C++G+YNL
Sbjct: 628 VGA----DPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNL 683

Query: 177 DGGNPEGCTQCFC 189
              +P+GC+ C C
Sbjct: 684 QELDPDGCSPCNC 696



 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 62/218 (28%), Positives = 89/218 (40%), Gaps = 44/218 (20%)

Query: 8    CCLCFSLLLPAARATSRREVCDCNGKSRQC--IFDRELHRQTGNGFRCLNCN-DNTD--- 61
            C    SL      A + + +C  N + RQC    +   + +  N F CL CN D T    
Sbjct: 797  CDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTIN 856

Query: 62   -------------------GIHCEKCKNGFYRHR--ERDRCLPCNCNSKGSLSAR-CDN- 98
                               G+ C +C+   Y         C  C C+S G+L    CD  
Sbjct: 857  GSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPI 916

Query: 99   SGRCSCKPGVTGARCDRCLPGFHML--TDAGCTQDQRLLDSKCDCDPAGIAGP-CDA--G 153
            SG+C C P   G RC++C PGF++      GC          C C   G     C++  G
Sbjct: 917  SGQCLCVPNRQGRRCNQCQPGFYISPGNATGCL--------PCSCHTTGAVNHICNSLTG 968

Query: 154  RCVCKPA-VTGERCDRCRSGYYNLDGGNPEGCTQCFCY 190
            +CVC+ A + G+RCD+C+  Y+  D      C  C C+
Sbjct: 969  QCVCQDASIAGQRCDQCKDHYFGFDPQTGR-CQPCNCH 1005



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 45/141 (31%), Positives = 69/141 (48%), Gaps = 13/141 (9%)

Query: 52   RCLNCNDNTDGIHCEKCKNGFY-RHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPG-V 108
            +CL C  N  G  C +C+ GFY        CLPC+C++ G+++  C++ +G+C C+   +
Sbjct: 919  QCL-CVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASI 977

Query: 109  TGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGER 165
             G RCD+C   +           Q      C+C  +G     C    G+C CK  VTG +
Sbjct: 978  AGQRCDQCKDHYFGF------DPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSK 1031

Query: 166  CDRCRSGYYNLDGGNPEGCTQ 186
            CD C     +LD  N  GC++
Sbjct: 1032 CDACVPSASHLDVNNLLGCSK 1052



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 24/77 (31%), Positives = 29/77 (37%), Gaps = 13/77 (16%)

Query: 131 DQRLLDSKCDCDPAGIAGPCDAG----RCVCKPA--VTGERCDRCRSGYYNL-----DGG 179
           D+  +  +C C   G A  CD      RC+C       G  CDRC   Y +      D  
Sbjct: 510 DEITISGRCQCH--GHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQV 567

Query: 180 NPEGCTQCFCYGHSASC 196
               C  C C  HS SC
Sbjct: 568 YAFNCKPCQCNSHSKSC 584


>gi|5453810 netrin 3 [Homo sapiens]
          Length = 580

 Score =  105 bits (261), Expect = 3e-22
 Identities = 64/179 (35%), Positives = 83/179 (46%), Gaps = 24/179 (13%)

Query: 7   GCCLCFSLLLPAARATSRRE----VCDCNGKSRQCIFDRELHRQTG--NGFRCLNCNDNT 60
           G C  F    P  RAT+R       C CNG +R+C F+ EL+R +G  +G  CLNC  NT
Sbjct: 286 GRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNT 345

Query: 61  DGIHCEKCKNGFYRH-----RERDRCLPCNCNSKGSLSARCD-NSGRCSCKPGVTGARCD 114
            G HC  C+ GFYR       +R  C  C+C+  G+    C+  +G+C CK GVTG  C+
Sbjct: 346 AGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCN 405

Query: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGY 173
           RC PGF           Q+       C    I GP +    V +P      C   R  Y
Sbjct: 406 RCAPGF-----------QQSRSPVAPCVKTPIPGPTEDSSPV-QPQDCDSHCKPARGSY 452



 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 51/156 (32%), Positives = 72/156 (46%), Gaps = 13/156 (8%)

Query: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRP---CQPCQ 518
           C C NG +   + +T+  +  +C  G  G  C  C   Y   P+ +    R    C  C 
Sbjct: 255 CKC-NGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPW-QRATARESHACLACS 312

Query: 519 CNNNVDPSASG-NCDRLTGR-----CLKCIHNTAGIYCDQCKAGYFGDP-LAPNPADKCR 571
           CN +           RL+GR     CL C HNTAG +C  C+ G++ DP  A +    CR
Sbjct: 313 CNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACR 372

Query: 572 ACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEHGA 606
           AC+C+P+G+    C ++ G C CK G  G  C   A
Sbjct: 373 ACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCA 408



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 49/184 (26%), Positives = 65/184 (35%), Gaps = 48/184 (26%)

Query: 382 CICPVGYKGQFCQDCASGY-----KRDSARLGPFGTCIPCNCQGGGACDPDTGDCY--SG 434
           C C  G +G  C  C   Y     +R +AR      C+ C+C G         + Y  SG
Sbjct: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESH--ACLACSCNGHARRCRFNMELYRLSG 331

Query: 435 DENPDI-----------ECADCPIGFYNDP----HDPRSCKPCPCHNGFSCSVMPETEEV 479
             +  +            C  C  GFY DP     D R+C+ C CH         +T   
Sbjct: 332 RRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCH---PVGAAGKTCNQ 388

Query: 480 VCNNCP--PGVTGARCELCADGYFGDPFGEHGPVRPC---------------QPCQCNNN 522
               CP   GVTG  C  CA G+         PV PC               QP  C+++
Sbjct: 389 TTGQCPCKDGVTGLTCNRCAPGF----QQSRSPVAPCVKTPIPGPTEDSSPVQPQDCDSH 444

Query: 523 VDPS 526
             P+
Sbjct: 445 CKPA 448



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 33/126 (26%), Positives = 44/126 (34%), Gaps = 22/126 (17%)

Query: 84  CNCNSKGSLSARC--DNSGR--CSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKC 139
           C CN   S   RC  D  G   C C+ G  G  C RC P +        T  +      C
Sbjct: 255 CKCNGHAS---RCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLAC 311

Query: 140 DCDPAG-----------IAGPCDAGRCV-CKPAVTGERCDRCRSGYYNLDG---GNPEGC 184
            C+              ++G    G C+ C+    G  C  CR G+Y   G    +   C
Sbjct: 312 SCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRAC 371

Query: 185 TQCFCY 190
             C C+
Sbjct: 372 RACDCH 377



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 15/52 (28%), Positives = 20/52 (38%), Gaps = 5/52 (9%)

Query: 155 CVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCFCYGHSASCRSSAE 201
           C C+    G  C RC+  Y +             C  C C GH+  CR + E
Sbjct: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNME 325


>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
          Length = 1044

 Score =  103 bits (256), Expect = 1e-21
 Identities = 76/242 (31%), Positives = 108/242 (44%), Gaps = 60/242 (24%)

Query: 370 PVSGAPAPWVEQCICPVGYKGQFCQD-CASGYKRDSARLGPFGTCIPCNCQGGGACDPDT 428
           P++GA       C+C  G++G  C++ CA G      +L       PC C+ G +CDP  
Sbjct: 156 PITGA-------CVCAAGFRGWRCEELCAPGTHGKGCQL-------PCQCRHGASCDPRA 201

Query: 429 GDCYSGDENPDIECAD-CPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPG 487
           G+C        + C + CP G +    + R    CPC NG +C  +  T E     CPPG
Sbjct: 202 GECLCAPGYTGVYCEELCPPGSHGAHCELR----CPCQNGGTCHHI--TGECA---CPPG 252

Query: 488 VTGARC-ELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTA 546
            TGA C + C  G FG            Q C C++       G CD +TG+C    H TA
Sbjct: 253 WTGAVCAQPCPPGTFGQ--------NCSQDCPCHH------GGQCDHVTGQC----HCTA 294

Query: 547 GIYCDQCKA----GYFGDPLAPNPADKCRACNCNPMGSEPVGCR-SDGTCVCKPGFGGPN 601
           G   D+C+     G FG   + +       C+C+  G     C  + G C C+PG+ GP 
Sbjct: 295 GYMGDRCQEECPFGSFGFQCSQH-------CDCHNGGQ----CSPTTGACECEPGYKGPR 343

Query: 602 CE 603
           C+
Sbjct: 344 CQ 345



 Score =  102 bits (254), Expect = 2e-21
 Identities = 90/290 (31%), Positives = 108/290 (37%), Gaps = 77/290 (26%)

Query: 366 ISARPVSGAPAPWVEQCICPVGYKGQFCQD-CASGYKRDSARLGPFGTCIPCNCQGGGAC 424
           IS  PV+GA       C C  G+ G  C + C  GY  D  +L       PC CQ G  C
Sbjct: 370 ISCHPVTGA-------CTCQPGWSGHHCNESCPVGYYGDGCQL-------PCTCQNGADC 415

Query: 425 DPDTGDCYSGDENPDIECA-DCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNN 483
              TG C          CA  C  G Y     P     C C+NG +CS  P      C  
Sbjct: 416 HSITGGCTCAPGFMGEVCAVSCAAGTYG----PNCSSICSCNNGGTCS--PVDGSCTCKE 469

Query: 484 ----------CPPGVTGARCE---LCADGYFGDPFGEHGPVRP------CQ-PC------ 517
                     CP G  G  C     CA+G    P        P      C+ PC      
Sbjct: 470 GWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFG 529

Query: 518 -QCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQ-CKAGYFGDPLAPNPADKCRACN- 574
             C+ + D S +  CD +TG C  C+    GI CD  C  G +G    PN +  C   N 
Sbjct: 530 LNCSEHCDCSHADGCDPVTGHCC-CLAGWTGIRCDSTCPPGRWG----PNCSVSCSCENG 584

Query: 575 --CNPMGSEPVGCRSDGTCVCKPGFGGPNCE---------HG-AFSCPAC 612
             C+P          DG+C C PGF GP C+         HG A  CP C
Sbjct: 585 GSCSP---------EDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLC 625



 Score = 97.4 bits (241), Expect = 6e-20
 Identities = 76/231 (32%), Positives = 97/231 (41%), Gaps = 49/231 (21%)

Query: 382 CICPVGYKGQFC-QDCASGY-KRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPD 439
           C C  G+ G  C Q CA GY  +D A+L        C+C   G C P  G C        
Sbjct: 639 CECLPGFSGALCNQVCAGGYFGQDCAQL--------CSCANNGTCSPIDGSCQCFPGWIG 690

Query: 440 IECAD-CPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARC-ELCA 497
            +C+  CP GF+     P     C CHNG SCS     E+  C+ C PG TG  C + C 
Sbjct: 691 KDCSQACPPGFWG----PACFHACSCHNGASCSA----EDGACH-CTPGWTGLFCTQRCP 741

Query: 498 DGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQ-CKAG 556
             +FG   G        + CQC N        +CD ++G+C  C     G +C+Q C  G
Sbjct: 742 AAFFGKDCG--------RVCQCQNGA------SCDHISGKCT-CRTGFTGQHCEQRCAPG 786

Query: 557 YFGDPLAPNPADKCRACNC-NPMGSEPVGCRSDGTCVCKPGFGGPNCEHGA 606
            FG           + C C N    + V     GTC C PGF G  C+  A
Sbjct: 787 TFGYGCQ-------QLCECMNNSTCDHV----TGTCYCSPGFKGIRCDQAA 826



 Score = 88.2 bits (217), Expect = 4e-17
 Identities = 79/246 (32%), Positives = 103/246 (41%), Gaps = 56/246 (22%)

Query: 377 PWVEQCICPVGYKGQFCQD-CASGYKRDSARLGPFGTCIPCNCQGGGACDPDTG--DCYS 433
           P    C C  G+ G  C   C  G      R GP    + C+C+ GG+C P+ G  +C  
Sbjct: 546 PVTGHCCCLAGWTGIRCDSTCPPG------RWGP-NCSVSCSCENGGSCSPEDGSCECAP 598

Query: 434 GDENPDIECADCPIGFYNDPHDPRSCKPCP--CHNGFSCSVMPETEEVVCNNCPPGVTGA 491
           G   P  +   CP GFY         +PCP   H+   C  +      +C  C PG +GA
Sbjct: 599 GFRGPLCQ-RICPPGFYGH----GCAQPCPLCVHSSRPCHHI----SGIC-ECLPGFSGA 648

Query: 492 RC-ELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYC 550
            C ++CA GYFG            Q C C NN      G C  + G C +C     G  C
Sbjct: 649 LCNQVCAGGYFGQDC--------AQLCSCANN------GTCSPIDGSC-QCFPGWIGKDC 693

Query: 551 DQ-CKAGYFGDPLAPNPADKC-RACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCEHGAF 607
            Q C  G++G      PA  C  AC+C+   S    C + DG C C PG+ G  C     
Sbjct: 694 SQACPPGFWG------PA--CFHACSCHNGAS----CSAEDGACHCTPGWTGLFCTQ--- 738

Query: 608 SCPACY 613
            CPA +
Sbjct: 739 RCPAAF 744



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 47/157 (29%), Positives = 61/157 (38%), Gaps = 36/157 (22%)

Query: 56  CNDNTDGIHCEKCKNGFYRHRERDRC----------LPCNCNSKGSLSARCDNSGRCSCK 105
           C+  T   HC     G+   R ++ C            C+C++ G  S     +G C C+
Sbjct: 283 CDHVTGQCHCTA---GYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSP---TTGACECE 336

Query: 106 PGVTGARCDR--CLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTG 163
           PG  G RC    C  G H     GCT     L   CD D      P   G C C+P  +G
Sbjct: 337 PGYKGPRCQERLCPEGLH---GPGCT-----LPCPCDADNTISCHPV-TGACTCQPGWSG 387

Query: 164 ERC-DRCRSGYYNLDGGNPEGC-TQCFCYGHSASCRS 198
             C + C  GYY       +GC   C C  + A C S
Sbjct: 388 HHCNESCPVGYYG------DGCQLPCTCQ-NGADCHS 417



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 49/173 (28%), Positives = 64/173 (36%), Gaps = 39/173 (22%)

Query: 7   GCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRC------LNCNDNT 60
           G C CF    P        + C        C      H    NG  C       +C    
Sbjct: 680 GSCQCF----PGWIGKDCSQACPPGFWGPACFHACSCH----NGASCSAEDGACHCTPGW 731

Query: 61  DGIHC-EKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD-RCL 117
            G+ C ++C   F+    +D    C C +     A CD+ SG+C+C+ G TG  C+ RC 
Sbjct: 732 TGLFCTQRCPAAFFG---KDCGRVCQCQN----GASCDHISGKCTCRTGFTGQHCEQRCA 784

Query: 118 PGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCD--AGRCVCKPAVTGERCDR 168
           PG       GC Q        C+C        CD   G C C P   G RCD+
Sbjct: 785 PG---TFGYGCQQ-------LCECMN---NSTCDHVTGTCYCSPGFKGIRCDQ 824



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 45/151 (29%), Positives = 57/151 (37%), Gaps = 37/151 (24%)

Query: 50  GFRCLNCNDN-TDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGV 108
           GFR   C +    G H + C+            LPC C    S   R   +G C C PG 
Sbjct: 166 GFRGWRCEELCAPGTHGKGCQ------------LPCQCRHGASCDPR---AGECLCAPGY 210

Query: 109 TGARCDR-CLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCD 167
           TG  C+  C PG H    A C       + +C C   G       G C C P  TG  C 
Sbjct: 211 TGVYCEELCPPGSH---GAHC-------ELRCPCQNGGTCHHI-TGECACPPGWTGAVCA 259

Query: 168 R-CRSGYYNLDGGNPEGCTQ-CFCYGHSASC 196
           + C  G +       + C+Q C C+ H   C
Sbjct: 260 QPCPPGTFG------QNCSQDCPCH-HGGQC 283



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 45/135 (33%), Positives = 55/135 (40%), Gaps = 26/135 (19%)

Query: 56  CNDNTDGIHC-EKCKNGFYRHRERDRC-LPCNCNSKGSLSARCDN-SGRCSCKPGVTGAR 112
           C     G HC E C  G+Y     D C LPC C +     A C + +G C+C PG  G  
Sbjct: 381 CQPGWSGHHCNESCPVGYYG----DGCQLPCTCQN----GADCHSITGGCTCAPGFMGEV 432

Query: 113 CD-RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCD-RCR 170
           C   C  G +      C+       S C C+  G   P D G C CK    G  C   C 
Sbjct: 433 CAVSCAAGTY---GPNCS-------SICSCNNGGTCSPVD-GSCTCKEGWQGLDCTLPCP 481

Query: 171 SGYYNLDGGNPEGCT 185
           SG + L+    E CT
Sbjct: 482 SGTWGLNCN--ESCT 494



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 59/201 (29%), Positives = 69/201 (34%), Gaps = 48/201 (23%)

Query: 27  VCDCNGKSRQCIFDRELHRQTG-NGFRC-LNCNDNTDGIHCEK---CKNGFYRHRERDRC 81
           +C CN        D     + G  G  C L C   T G++C +   C NG         C
Sbjct: 449 ICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSC 508

Query: 82  ------------LPCNCNSKG-SLSARCDNS---------GRCSCKPGVTGARCD-RCLP 118
                       LPC   + G + S  CD S         G C C  G TG RCD  C P
Sbjct: 509 SCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPP 568

Query: 119 GFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDR-CRSGYYNLD 177
           G        C+         C C+  G   P D G C C P   G  C R C  G+Y   
Sbjct: 569 G---RWGPNCS-------VSCSCENGGSCSPED-GSCECAPGFRGPLCQRICPPGFYG-- 615

Query: 178 GGNPEGCTQ-C-FCYGHSASC 196
                GC Q C  C   S  C
Sbjct: 616 ----HGCAQPCPLCVHSSRPC 632



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 45/151 (29%), Positives = 60/151 (39%), Gaps = 30/151 (19%)

Query: 56  CNDNTDGIHCEK-CKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARC 113
           C     G  C++ C  GFY H     C  C  +S+      C + SG C C PG +GA C
Sbjct: 596 CAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRP-----CHHISGICECLPGFSGALC 650

Query: 114 DRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDR-CRSG 172
           ++   G +   D  C Q        C C   G   P D G C C P   G+ C + C  G
Sbjct: 651 NQVCAGGYFGQD--CAQ-------LCSCANNGTCSPID-GSCQCFPGWIGKDCSQACPPG 700

Query: 173 YYNLDGGNPEGCTQCFCYGHSASCRSSAEYS 203
           ++            CF   H+ SC + A  S
Sbjct: 701 FWG---------PACF---HACSCHNGASCS 719



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 38/134 (28%), Positives = 52/134 (38%), Gaps = 27/134 (20%)

Query: 67  KCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDA 126
           +C  G+Y     D C+P  C  +  +  RC +   C C+PG  G  C            +
Sbjct: 87  QCCPGYYE--SGDFCIPL-CTEE-CVHGRCVSPDTCHCEPGWGGPDC-----------SS 131

Query: 127 GCTQDQ--RLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDR-CRSGYYNLDGGNPEG 183
           GC  D       ++C C    +  P   G CVC     G RC+  C  G +       +G
Sbjct: 132 GCDSDHWGPHCSNRCQCQNGALCNPI-TGACVCAAGFRGWRCEELCAPGTHG------KG 184

Query: 184 C-TQCFCYGHSASC 196
           C   C C  H ASC
Sbjct: 185 CQLPCQC-RHGASC 197



 Score = 38.1 bits (87), Expect = 0.047
 Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 15/73 (20%)

Query: 552 QCKAGYF--GDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAFS- 608
           QC  GY+  GD   P   ++C    C           S  TC C+PG+GGP+C  G  S 
Sbjct: 87  QCCPGYYESGDFCIPLCTEECVHGRCV----------SPDTCHCEPGWGGPDCSSGCDSD 136

Query: 609 --CPACYNQVKIQ 619
              P C N+ + Q
Sbjct: 137 HWGPHCSNRCQCQ 149



 Score = 37.4 bits (85), Expect = 0.080
 Identities = 21/63 (33%), Positives = 24/63 (38%), Gaps = 8/63 (12%)

Query: 381 QCICPVGYKGQFC-QDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPD 439
           +C C  G+ GQ C Q CA G          +G    C C     CD  TG CY       
Sbjct: 767 KCTCRTGFTGQHCEQRCAPG-------TFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKG 819

Query: 440 IEC 442
           I C
Sbjct: 820 IRC 822


>gi|93204871 netrin 4 [Homo sapiens]
          Length = 628

 Score =  102 bits (254), Expect = 2e-21
 Identities = 61/144 (42%), Positives = 74/144 (51%), Gaps = 20/144 (13%)

Query: 21  ATSRREVCDCNGKSRQCIFDRELHRQTGN--GFRCLNCNDNTDGIHCEKCKNGFYRHRER 78
           A +    C CNG +  C FD  +   +GN  G  C +C  NT+G +C++CK GFYR   R
Sbjct: 325 APNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRR 384

Query: 79  -----DRCLPCNCNSKGS--LSAR----CDNS-GRCSCKPGVTGARCDRCLPGFHMLTDA 126
                D C PC+C+  GS  L A     CD S G C CKPGV G RCDRC+ G+    D 
Sbjct: 385 PFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDY 444

Query: 127 GCTQDQRLLDSKCDCDPAGIAGPC 150
           GC    R  D    CDP  I G C
Sbjct: 445 GC----RPCDCAGSCDP--ITGDC 462



 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 60/180 (33%), Positives = 79/180 (43%), Gaps = 33/180 (18%)

Query: 463 PCHNGFSCSVMPETEEVVCNNC--PPGVTGARCELCADGYFGDPF----GEHGPVRPCQP 516
           P H GF     P T  +V   C       G+ C+ CA  Y   P+    G+ G    C+ 
Sbjct: 273 PVH-GFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRT 331

Query: 517 CQCNNNVDP--------SASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPA- 567
           C+CN + D          ASGN  R  G C  C HNT G YC +CK G++ D   P  A 
Sbjct: 332 CKCNGHADTCHFDVNVWEASGN--RSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAP 389

Query: 568 DKCRACNCNPMGSEPVGCR-------SDGTCVCKPGFGGPNCEH--------GAFSCPAC 612
           D C+ C+C+P+GS  +          S+G C CKPG  G  C+         G + C  C
Sbjct: 390 DACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPC 449



 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 61/193 (31%), Positives = 77/193 (39%), Gaps = 55/193 (28%)

Query: 381 QCICPVGYKGQFCQDCASGY-----KRDSARLGPFGTCIPCNCQG--------------- 420
           +C+C     G  CQ CA  Y     +    + G    C  C C G               
Sbjct: 292 KCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEAS 351

Query: 421 ----GGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRS----CKPCPCHNGFSCSV 472
               GG CD    DC    E     C  C  GFY D   P S    CKPC CH     +V
Sbjct: 352 GNRSGGVCD----DCQHNTEGQ--YCQRCKPGFYRDLRRPFSAPDACKPCSCH-PVGSAV 404

Query: 473 MPETEEVVCN------NCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPS 526
           +P      C+       C PGV G RC+ C  GY+G  FG++G    C+PC C       
Sbjct: 405 LPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWG--FGDYG----CRPCDC------- 451

Query: 527 ASGNCDRLTGRCL 539
            +G+CD +TG C+
Sbjct: 452 -AGSCDPITGDCI 463



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 24/58 (41%), Positives = 29/58 (50%), Gaps = 7/58 (12%)

Query: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPD 439
           C C  G  G+ C  C  GY       G +G C PC+C   G+CDP TGDC S   + D
Sbjct: 420 CPCKPGVAGRRCDRCMVGYWG----FGDYG-CRPCDC--AGSCDPITGDCISSHTDID 470


>gi|190014607 netrin G2 [Homo sapiens]
          Length = 530

 Score = 97.4 bits (241), Expect = 6e-20
 Identities = 53/160 (33%), Positives = 76/160 (47%), Gaps = 21/160 (13%)

Query: 28  CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR-----ERDRCL 82
           C+C G S +C +   L+  T     C++C  NT G HC+ C+ G+YR+      + + C+
Sbjct: 353 CECYGHSNRCSYIDFLNVVT-----CVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCI 407

Query: 83  PCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLLDSKC 139
            CNCN  GS+  RC+ +G C C+ G  G +CD CLP  +         C  DQ L  +  
Sbjct: 408 ECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGG 467

Query: 140 DCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGG 179
            C            RC C    TG RC++ R    + DGG
Sbjct: 468 TC--------LQNQRCACPRGYTGVRCEQPRCDPADDDGG 499



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 41/141 (29%), Positives = 54/141 (38%), Gaps = 29/141 (20%)

Query: 484 CPPGVTGARCELC----------ADGYFGDPFGEHGPVRPCQP------CQCNNNVDPSA 527
           C    TG  C  C          A  Y   P   HG    C        C+C  +     
Sbjct: 307 CEHNTTGPDCGKCKKNFRTRSWRAGSYLPLP---HGSPNACATAGSFGNCECYGH----- 358

Query: 528 SGNCDRL----TGRCLKCIHNTAGIYCDQCKAGYFGDPLAP-NPADKCRACNCNPMGSEP 582
           S  C  +       C+ C HNT G +C  C+ GY+ +  A  +  + C  CNCN +GS  
Sbjct: 359 SNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVH 418

Query: 583 VGCRSDGTCVCKPGFGGPNCE 603
             C   G C C+ G  GP C+
Sbjct: 419 DRCNETGFCECREGAAGPKCD 439



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 51/195 (26%), Positives = 67/195 (34%), Gaps = 15/195 (7%)

Query: 414 IPCNCQGGGACDPDTGDCYSGDENPDIECAD---CPIGFYNDPHDPRSCKPCPCHNGFS- 469
           + C C+      PD G C                 P G  N      S   C C+   + 
Sbjct: 303 LQCECEHN-TTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNR 361

Query: 470 CSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASG 529
           CS +     V C +C     G  C+ C  GY+ +   E      C  C CN     S   
Sbjct: 362 CSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQ--IGSVHD 419

Query: 530 NCDRLTGRCLKCIHNTAGIYCDQC-KAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD 588
            C+  TG C +C    AG  CD C    Y+     PN  D  +   C   G+    C  +
Sbjct: 420 RCNE-TGFC-ECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLL-CQNGGT----CLQN 472

Query: 589 GTCVCKPGFGGPNCE 603
             C C  G+ G  CE
Sbjct: 473 QRCACPRGYTGVRCE 487



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 43/125 (34%), Positives = 55/125 (44%), Gaps = 16/125 (12%)

Query: 379 VEQCI-CPVGYKGQFCQDCASGYKRD-SARLGPFGTCIPCNCQGGGA----CDPDTGDCY 432
           V  C+ C    +GQ CQ C  GY R+ SA L     CI CNC   G+    C+ +TG C 
Sbjct: 370 VVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFCE 428

Query: 433 SGDENPDIECADC-PIGFYNDPHDPRSC--KPCPCHNGFSCSVMPETEEVVCNNCPPGVT 489
             +     +C DC P  ++     P  C      C NG +C      +   C  CP G T
Sbjct: 429 CREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC-----LQNQRC-ACPRGYT 482

Query: 490 GARCE 494
           G RCE
Sbjct: 483 GVRCE 487



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 48/181 (26%), Positives = 65/181 (35%), Gaps = 35/181 (19%)

Query: 28  CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCL----- 82
           C CN  +  C   RE         +C  C  NT G  C KCK  F     R         
Sbjct: 287 CKCNLHANLCSM-RE------GSLQC-ECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPH 338

Query: 83  --PCNCNSKGSLSARCD---NSGRCS------------CKPGVTGARCDRCLPGFHMLTD 125
             P  C + GS    C+   +S RCS            CK    G  C  C  G++   +
Sbjct: 339 GSPNACATAGSFG-NCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYR--N 395

Query: 126 AGCTQDQRLLDSKCDCDPAG-IAGPC-DAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEG 183
                D   +  +C+C+  G +   C + G C C+    G +CD C   +Y   G  P  
Sbjct: 396 GSAELDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNV 455

Query: 184 C 184
           C
Sbjct: 456 C 456



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 35/127 (27%), Positives = 47/127 (37%), Gaps = 23/127 (18%)

Query: 84  CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDP 143
           C CN   +L +  + S +C C+   TG  C +C   F   +    +       S   C  
Sbjct: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346

Query: 144 AGIAGPCD----AGRC------------VCKPAVTGERCDRCRSGYY-----NLDGGNPE 182
           AG  G C+    + RC             CK    G+ C  CR GYY      LD  N  
Sbjct: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV- 405

Query: 183 GCTQCFC 189
            C +C C
Sbjct: 406 -CIECNC 411



 Score = 35.0 bits (79), Expect = 0.39
 Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 16/59 (27%)

Query: 154 RCVCKPAVTGERCDRCRSG----------YYNLDGGNPEGCT------QCFCYGHSASC 196
           +C C+   TG  C +C+            Y  L  G+P  C        C CYGHS  C
Sbjct: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRC 362


>gi|164414431 netrin G1 isoform 1 [Homo sapiens]
          Length = 539

 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 56/153 (36%), Positives = 76/153 (49%), Gaps = 25/153 (16%)

Query: 28  CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR-----ERDRCL 82
           C+C G S +C +   L     N   C++C  NT G HCE C+ G++R+      + + C+
Sbjct: 364 CECFGHSNRCSYIDLL-----NTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCI 418

Query: 83  PCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPG--FHMLTDAGCTQ---DQRLLDS 137
            C CN  GS+  RC+ SG C CK G TG +CD CLPG  +H     GC     D  LL  
Sbjct: 419 ECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHY----GCQPNVCDNELL-- 472

Query: 138 KCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCR 170
              C   G     +  RC+C  A TG  C++ R
Sbjct: 473 --HCQNGGTCH--NNVRCLCPAAYTGILCEKLR 501



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 51/160 (31%), Positives = 69/160 (43%), Gaps = 24/160 (15%)

Query: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQC 519
           C C+   +  V  +  ++ C  C    TG  C  C   Y G P+  G + P+    P   
Sbjct: 297 CKCNLHATVCVY-DNSKLTCE-CEHNTTGPDCGKCKKNYQGRPWSPGSYLPI----PKGT 350

Query: 520 NNNVDPSAS--GNCDRL-------------TGRCLKCIHNTAGIYCDQCKAGYFGDPLAP 564
            N   PS S  GNC+               T  C+ C HNT G +C+ C+ GYF +  A 
Sbjct: 351 ANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQ 410

Query: 565 -NPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE 603
            +  + C  C CNP+GS    C   G C CK G  GP C+
Sbjct: 411 LDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCD 450



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 52/182 (28%), Positives = 68/182 (37%), Gaps = 36/182 (19%)

Query: 28  CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR----------- 76
           C CN  +  C++D        N      C  NT G  C KCK  +               
Sbjct: 297 CKCNLHATVCVYD--------NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPK 348

Query: 77  -ERDRCLPC-----NCNSKGSLSARCD-----NSGRC-SCKPGVTGARCDRCLPGFHMLT 124
              + C+P      NC   G  S RC      N+  C SCK    G  C+ C  G+    
Sbjct: 349 GTANTCIPSISSIGNCECFGH-SNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGY--FR 405

Query: 125 DAGCTQDQRLLDSKCDCDPAG-IAGPCD-AGRCVCKPAVTGERCDRCRSGYYNLDGGNPE 182
           +A    D   +  +C C+P G I   C+ +G C CK   TG +CD C  G     G  P 
Sbjct: 406 NASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPN 465

Query: 183 GC 184
            C
Sbjct: 466 VC 467



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 50/211 (23%), Positives = 66/211 (31%), Gaps = 61/211 (28%)

Query: 428 TGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCP------CHNGFS------------ 469
           T +C      PD  C  C   +   P  P S  P P      C    S            
Sbjct: 314 TCECEHNTTGPD--CGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSN 371

Query: 470 -CSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSAS 528
            CS +     V+C +C     G  CELC  GYF +                       AS
Sbjct: 372 RCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRN-----------------------AS 408

Query: 529 GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRAC--------NCNP--M 578
              D     C++C  N  G   D+C    F +        KC  C         C P   
Sbjct: 409 AQLDD-ENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVC 467

Query: 579 GSEPVGCRSDGT------CVCKPGFGGPNCE 603
            +E + C++ GT      C+C   + G  CE
Sbjct: 468 DNELLHCQNGGTCHNNVRCLCPAAYTGILCE 498



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 43/144 (29%), Positives = 57/144 (39%), Gaps = 30/144 (20%)

Query: 384 CPVGYKGQFCQDCASGYKRD-SARLGPFGTCIPC----------NCQGGGACDPDTGDCY 432
           C    +GQ C+ C  GY R+ SA+L     CI C           C G G C     +C 
Sbjct: 387 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFC-----ECK 441

Query: 433 SGDENPDIECADC-PIGFYNDPHDPRSC--KPCPCHNGFSCSVMPETEEVVCNNCPPGVT 489
           +G   P  +C +C P   ++    P  C  +   C NG +C        V C  CP   T
Sbjct: 442 TGTTGP--KCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCH-----NNVRC-LCPAAYT 493

Query: 490 GARCE--LCAD-GYFGDPFGEHGP 510
           G  CE   C + G  G   G+  P
Sbjct: 494 GILCEKLRCEEAGSCGSDSGQGAP 517


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,028,479
Number of Sequences: 37866
Number of extensions: 2349349
Number of successful extensions: 15126
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 153
Number of HSP's successfully gapped in prelim test: 653
Number of HSP's that attempted gapping in prelim test: 7875
Number of HSP's gapped (non-prelim): 3796
length of query: 1111
length of database: 18,247,518
effective HSP length: 113
effective length of query: 998
effective length of database: 13,968,660
effective search space: 13940722680
effective search space used: 13940722680
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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