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Search of human proteins with 157419140
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157419140 laminin, gamma 2 isoform b precursor [Homo
sapiens]
(1111 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 2307 0.0
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 2303 0.0
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 805 0.0
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 565 e-161
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 358 2e-98
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 313 6e-85
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 313 6e-85
gi|21264602 laminin alpha 5 [Homo sapiens] 301 2e-81
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 245 2e-64
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 235 2e-61
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 225 2e-58
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 167 4e-41
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 159 1e-38
gi|143770880 laminin, beta 4 [Homo sapiens] 158 3e-38
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 135 2e-31
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 135 2e-31
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 135 2e-31
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 132 2e-30
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 129 1e-29
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 129 1e-29
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 124 5e-28
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 120 5e-27
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 114 4e-25
gi|219842266 usherin isoform B [Homo sapiens] 105 2e-22
gi|219842259 usherin isoform A [Homo sapiens] 105 2e-22
gi|5453810 netrin 3 [Homo sapiens] 105 3e-22
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 103 1e-21
gi|93204871 netrin 4 [Homo sapiens] 102 2e-21
gi|190014607 netrin G2 [Homo sapiens] 97 6e-20
gi|164414431 netrin G1 isoform 1 [Homo sapiens] 96 2e-19
>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
Length = 1111
Score = 2307 bits (5979), Expect = 0.0
Identities = 1111/1111 (100%), Positives = 1111/1111 (100%)
Query: 1 MPALWLGCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNT 60
MPALWLGCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNT
Sbjct: 1 MPALWLGCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNT 60
Query: 61 DGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGF 120
DGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGF
Sbjct: 61 DGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGF 120
Query: 121 HMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGN 180
HMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGN
Sbjct: 121 HMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGN 180
Query: 181 PEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVF 240
PEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVF
Sbjct: 181 PEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVF 240
Query: 241 SSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPL 300
SSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPL
Sbjct: 241 SSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPL 300
Query: 301 MPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYI 360
MPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYI
Sbjct: 301 MPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYI 360
Query: 361 DNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG 420
DNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG
Sbjct: 361 DNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG 420
Query: 421 GGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV 480
GGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV
Sbjct: 421 GGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV 480
Query: 481 CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK 540
CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK
Sbjct: 481 CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK 540
Query: 541 CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGP 600
CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGP
Sbjct: 541 CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGP 600
Query: 601 NCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQAL 660
NCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQAL
Sbjct: 601 NCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQAL 660
Query: 661 QDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTH 720
QDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTH
Sbjct: 661 QDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTH 720
Query: 721 RLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTR 780
RLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTR
Sbjct: 721 RLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTR 780
Query: 781 ETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIE 840
ETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIE
Sbjct: 781 ETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIE 840
Query: 841 ADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLG 900
ADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLG
Sbjct: 841 ADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLG 900
Query: 901 NWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDL 960
NWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDL
Sbjct: 901 NWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDL 960
Query: 961 QVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE 1020
QVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE
Sbjct: 961 QVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE 1020
Query: 1021 IEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITE 1080
IEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITE
Sbjct: 1021 IEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITE 1080
Query: 1081 AQKVDTRAKNAGVTIQDTLNTLDGLLHLMGM 1111
AQKVDTRAKNAGVTIQDTLNTLDGLLHLMGM
Sbjct: 1081 AQKVDTRAKNAGVTIQDTLNTLDGLLHLMGM 1111
>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
Length = 1193
Score = 2303 bits (5968), Expect = 0.0
Identities = 1109/1109 (100%), Positives = 1109/1109 (100%)
Query: 1 MPALWLGCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNT 60
MPALWLGCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNT
Sbjct: 1 MPALWLGCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNT 60
Query: 61 DGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGF 120
DGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGF
Sbjct: 61 DGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGF 120
Query: 121 HMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGN 180
HMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGN
Sbjct: 121 HMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGN 180
Query: 181 PEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVF 240
PEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVF
Sbjct: 181 PEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVF 240
Query: 241 SSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPL 300
SSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPL
Sbjct: 241 SSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPL 300
Query: 301 MPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYI 360
MPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYI
Sbjct: 301 MPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYI 360
Query: 361 DNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG 420
DNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG
Sbjct: 361 DNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG 420
Query: 421 GGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV 480
GGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV
Sbjct: 421 GGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV 480
Query: 481 CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK 540
CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK
Sbjct: 481 CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK 540
Query: 541 CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGP 600
CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGP
Sbjct: 541 CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGP 600
Query: 601 NCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQAL 660
NCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQAL
Sbjct: 601 NCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQAL 660
Query: 661 QDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTH 720
QDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTH
Sbjct: 661 QDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTH 720
Query: 721 RLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTR 780
RLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTR
Sbjct: 721 RLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTR 780
Query: 781 ETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIE 840
ETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIE
Sbjct: 781 ETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIE 840
Query: 841 ADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLG 900
ADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLG
Sbjct: 841 ADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLG 900
Query: 901 NWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDL 960
NWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDL
Sbjct: 901 NWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDL 960
Query: 961 QVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE 1020
QVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE
Sbjct: 961 QVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE 1020
Query: 1021 IEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITE 1080
IEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITE
Sbjct: 1021 IEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITE 1080
Query: 1081 AQKVDTRAKNAGVTIQDTLNTLDGLLHLM 1109
AQKVDTRAKNAGVTIQDTLNTLDGLLHLM
Sbjct: 1081 AQKVDTRAKNAGVTIQDTLNTLDGLLHLM 1109
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 805 bits (2080), Expect = 0.0
Identities = 441/1230 (35%), Positives = 669/1230 (54%), Gaps = 151/1230 (12%)
Query: 9 CLCFSLLLPAARATSRREV----CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIH 64
CL F P RAT+ CDCNG+S++C FD EL+R TG+G C NC DNTDG H
Sbjct: 319 CLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAH 378
Query: 65 CEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLT 124
CE+C+ F+R + C C+C+ GSLS +CD+ GRCSCKPGV G +CDRC PGFH LT
Sbjct: 379 CERCRENFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLT 438
Query: 125 DAGCTQDQRLLDSKCDCDPAGIAGPC--DAGRCVCKPAVTGERCDRCRSGYYNLDGGNPE 182
+AGC C CDP+G C + GRCVCK V G C+RC+ G++NL+ NP
Sbjct: 439 EAGCRP--------CSCDPSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPR 490
Query: 183 GCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVFSS 242
GCT CFC+GHS+ C ++ YSV+ I+STF D DGW+A QR+GS A L+WS QD+
Sbjct: 491 GCTPCFCFGHSSVCTNAVGYSVYSISSTFQIDEDGWRAEQRDGSEASLEWSSERQDIAVI 550
Query: 243 AQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPLMP 302
+ P YF+APAKFLG Q +SYGQ+LSF +RVDR SA D++LEGAGLR++ PL+
Sbjct: 551 SDSYFPRYFIAPAKFLGKQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVSVPLIA 610
Query: 303 LGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYIDN 362
G + P T Y FRL+E W P L+ FE+++LL NLT+++IR TY E S GY+D+
Sbjct: 611 QGNSYPSETTVKYVFRLHEATDYPWRPALTPFEFQKLLNNLTSIKIRGTYSERSAGYLDD 670
Query: 363 VTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG 422
VTL SARP G PA WVE C CPVGY GQFC+ C SGY+R++ LGP+ C+ C C G
Sbjct: 671 VTLASARPGPGVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHS 730
Query: 423 -ACDPDTGDC-----------------YSGD------------------------ENPDI 440
CDP+TG C Y GD + ++
Sbjct: 731 ETCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEV 790
Query: 441 ECADCPIG------------FYNDP---HDP-RSCKPCPCHNGFSCSVMPETEEVV--CN 482
C +CP G ++ DP + P R C+ C C + + + + C
Sbjct: 791 VCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECL 850
Query: 483 NCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCN---------------------- 520
C G C+ C DG+FG+P + P C+ C CN
Sbjct: 851 KCIYNTAGFYCDRCKDGFFGNPLAPN-PADKCKACNCNLYGTMKQQSSCNPVTGQCECLP 909
Query: 521 -------NNVDP--------------------SASGNCDRLTGRCLKCIHNTAGIYCDQC 553
DP S +G CD TG+C +C G +C++C
Sbjct: 910 HVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQC-ECQPGITGQHCERC 968
Query: 554 KAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEH--------- 604
+ +FG P + C+ C+C+P GS + C+ DG C C+ GF G C+
Sbjct: 969 EVNHFG--FGP---EGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNR 1023
Query: 605 ---GAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQ 661
G CPACY VK ++ +LQ +E+LI+ GD +V D E R+++AE+ +
Sbjct: 1024 SWPGCQECPACYRLVKDKVADHRVKLQELESLIANLGTGDEMVTDQAFEDRLKEAEREVM 1083
Query: 662 DILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHR 721
D+LR+AQ + ++L +L +V + +S SRL +++ T+E L Q + V +T R
Sbjct: 1084 DLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVENTER 1143
Query: 722 LITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRE 781
LI L +++ + N ++ + PN LA+EA +LAE H + A ++ ++ +
Sbjct: 1144 LIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKT 1203
Query: 782 TEDYSKQALSLVRKALHEGVGSGSGSPDGAV-VQGLVEKLEKTKSLAQQLTREATQAEIE 840
D S +A +L+ + L +G A ++ L K E+ K+++Q L ++A + E
Sbjct: 1204 ANDTSTEAYNLLLRTL-------AGENQTAFEIEELNRKYEQAKNISQDLEKQAARVHEE 1256
Query: 841 ADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLG 900
A R+ ++ + SV++L + ++ + EA IK +A++L L+ + + +++ ++++
Sbjct: 1257 AKRAGDKAVEIYASVAQLSPLDSETLE-NEANNIKMEAENLEQLIDQKLKDYEDLREDMR 1315
Query: 901 NWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDL 960
+ E + LL+ GK+ ++ +DQLL+RA+ AK+ A+EA G T E IL NL++FD
Sbjct: 1316 GKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDR 1375
Query: 961 QVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE 1020
+V++ K AEEA++++ I+Q +++A++KT++A++ALGSAAADA AKN A EA I+S
Sbjct: 1376 RVNDNKTAAEEALRKIPAINQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASA 1435
Query: 1021 IEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITE 1080
+++ S EA T ++ + ++ +++E E EL+RK+ + D +M M
Sbjct: 1436 VQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQA 1495
Query: 1081 AQKVDTRAKNAGVTIQDTLNTLDGLLHLMG 1110
AQ+ + A+ A ++ L+ ++ LL +G
Sbjct: 1496 AQEAEINARKAKNSVTSLLSIINDLLEQLG 1525
Score = 628 bits (1620), Expect = e-180
Identities = 312/662 (47%), Positives = 391/662 (59%), Gaps = 97/662 (14%)
Query: 28 CDCNGKSRQCI---FDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR-------- 76
C CNG + +C+ FD+ + NC NT G+ CEKC F+ R
Sbjct: 286 CKCNGHASECMKNEFDKLV----------CNCKHNTYGVDCEKCL-PFFNDRPWRRATAE 334
Query: 77 ERDRCLPCNCNSK----------------------------GSLSARC------------ 96
CLPC+CN + G+ RC
Sbjct: 335 SASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEA 394
Query: 97 ----------------DNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCD 140
D+ GRCSCKPGV G +CDRC PGFH LT+AGC C
Sbjct: 395 CSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGC--------RPCS 446
Query: 141 CDPAGIAGPC--DAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRS 198
CDP+G C + GRCVCK V G C+RC+ G++NL+ NP GCT CFC+GHS+ C +
Sbjct: 447 CDPSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTN 506
Query: 199 SAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFL 258
+ YSV+ I+STF D DGW+A QR+GS A L+WS QD+ + P YF+APAKFL
Sbjct: 507 AVGYSVYSISSTFQIDEDGWRAEQRDGSEASLEWSSERQDIAVISDSYFPRYFIAPAKFL 566
Query: 259 GNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFR 318
G Q +SYGQ+LSF +RVDR SA D++LEGAGLR++ PL+ G + P T Y FR
Sbjct: 567 GKQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVSVPLIAQGNSYPSETTVKYVFR 626
Query: 319 LNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYIDNVTLISARPVSGAPAPW 378
L+E W P L+ FE+++LL NLT+++IR TY E S GY+D+VTL SARP G PA W
Sbjct: 627 LHEATDYPWRPALTPFEFQKLLNNLTSIKIRGTYSERSAGYLDDVTLASARPGPGVPATW 686
Query: 379 VEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDEN 437
VE C CPVGY GQFC+ C SGY+R++ LGP+ C+ C C G CDP+TG C D
Sbjct: 687 VESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVCNCRDNT 746
Query: 438 PDIECADCPIGFYNDPHDPRS--CKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCEL 495
C C G+Y D S C+PCPC G SC+V+P+T+EVVC NCP G TG RCEL
Sbjct: 747 AGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCEL 806
Query: 496 CADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKA 555
C DGYFGDP G +GPVR C+ CQC++N+DP+A GNC+RLTG CLKCI+NTAG YCD+CK
Sbjct: 807 CDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKD 866
Query: 556 GYFGDPLAPNPADKCRACNCNPMGS--EPVGCRS-DGTCVCKPGFGGPNCEHGAFSCPAC 612
G+FG+PLAPNPADKC+ACNCN G+ + C G C C P G +C GA P
Sbjct: 867 GFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDC--GACD-PGF 923
Query: 613 YN 614
YN
Sbjct: 924 YN 925
Score = 65.5 bits (158), Expect = 3e-10
Identities = 82/432 (18%), Positives = 175/432 (40%), Gaps = 44/432 (10%)
Query: 654 QQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQ 713
++ +Q DI+R A+ + S L + + EN +++L E+ + + +
Sbjct: 1188 ERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQAKNISQDLE 1247
Query: 714 NRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESAS 773
+ H + E AS+ + P ++L EA + A
Sbjct: 1248 KQAARVHEEAKRAGDKAVEIYASVAQ---------LSPLDSETLENEANNIKME----AE 1294
Query: 774 NMEQLT-RETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTR 832
N+EQL ++ +DY + K L G + L+ + + K+LA++ +
Sbjct: 1295 NLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAK 1354
Query: 833 EATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEF 892
+ EA+ ++L+ D + V+D EEA R K +++ +T ++
Sbjct: 1355 KGRDTLQEAN-DILNNLKDFD-----RRVNDNKTAAEEALR---KIPAINQTITEANEKT 1405
Query: 893 KRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESIL 952
+ Q+ LG+ +A + + + A K+ A+ + EV ++L
Sbjct: 1406 REAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNML 1465
Query: 953 KNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAG 1012
K L+E + ++ ++ +A++ M SQ +A +A++AKN
Sbjct: 1466 KQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAE--------------INARKAKNSVT 1511
Query: 1013 EALEISSEIEQEIGSL---NLEANVTADGALAMEKG---LASLKSEMREVEGELERKELE 1066
L I +++ +++G L +L +G L K ++ L ++ ++E E +++E
Sbjct: 1512 SLLSIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAKKQEAA 1571
Query: 1067 -FDTNMDAVQMV 1077
D N D +++
Sbjct: 1572 IMDYNRDIEEIM 1583
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 565 bits (1456), Expect = e-161
Identities = 278/608 (45%), Positives = 356/608 (58%), Gaps = 27/608 (4%)
Query: 9 CLCFSLLLPAARATSRRE----VCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIH 64
CL F P AR T+ C+C+G+S +C FDREL R TG+G RC +C D+T G H
Sbjct: 304 CLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPH 363
Query: 65 CEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLT 124
CE+C+ FY R C PC+C S GSL +CD++G C+CKP VTG +CDRCLPGFH L+
Sbjct: 364 CERCQENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLS 423
Query: 125 DAGCTQDQRLLDSKCDCDPAGIAGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPE 182
+ GC C C+PAG CD +GRC CK V G CDRCR G +NL NP
Sbjct: 424 EGGCRP--------CTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPA 475
Query: 183 GCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVFSS 242
GC+ CFCYGHS C S+A++ VH I S FHQ +GW A GS QWS V S
Sbjct: 476 GCSSCFCYGHSKVCASTAQFQVHHILSDFHQGAEGWWARSVGGSEHPPQWSPN--GVLLS 533
Query: 243 AQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPLMP 302
+ D AP KFLG+Q+ SYGQ L +RV G P + LEG GL ++
Sbjct: 534 PE--DEEELTAPEKFLGDQRFSYGQPLILTFRVPPGDS-PLPVQLRLEGTGLALSLRHSS 590
Query: 303 LGKTLPCGLTKTYTFRLN-EHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTG--Y 359
L G + R + + S + +P L F ++RLL NLT+LR+R + G G +
Sbjct: 591 LSGPQDAGHPREVELRFHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSPGPSPAGPVF 650
Query: 360 IDNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQ 419
+ V L SARP PA WVE C CP GY GQFC+ CA GYKR+ + GP+ +C+PC C
Sbjct: 651 LTEVRLTSARPGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCN 710
Query: 420 GGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRS--CKPCPCHNGFSCSVMPETE 477
G CDP+TG C C C GFY +P ++ C+PCPC +C+ +PE+
Sbjct: 711 QHGTCDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESR 770
Query: 478 EVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGR 537
EVVC +CPPG G RCE+C DG+FGDP G G +PC CQC+ NVDP+A GNCD L+G
Sbjct: 771 EVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGH 830
Query: 538 CLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG--SEPVGCRS-DGTCVCK 594
CL+C+HNT G +C+ C+ G++G LAP PADKC C+C+P G SE + C G C C
Sbjct: 831 CLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCL 890
Query: 595 PGFGGPNC 602
P +C
Sbjct: 891 PHVTARDC 898
Score = 182 bits (462), Expect = 2e-45
Identities = 188/762 (24%), Positives = 304/762 (39%), Gaps = 80/762 (10%)
Query: 384 CPVGYKGQFCQDCASGYKRDSARLGPFG---TCIPCNCQGG------GACDPDTGDCYSG 434
CP G +G+ C+ C G+ D LG FG C C C G G CDP +G C
Sbjct: 777 CPPGQRGRRCEVCDDGFFGDP--LGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRC 834
Query: 435 DENPDIE-CADCPIGFYNDPHDPR---SCKPCPCHNGFSCSVMPETEEVVCN-NCPPGVT 489
N + C C GFY PR C PC CH S S + V +C P VT
Sbjct: 835 LHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVT 894
Query: 490 GARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIY 549
C C G+F + P R C+ C+C+ S C TG+C C G
Sbjct: 895 ARDCSRCYPGFF-----DLQPGRGCRSCKCHPL--GSQEDQCHPKTGQCT-CRPGVTGQA 946
Query: 550 CDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE--HGAF 607
CD+C+ G+FG + CRAC C+P+G+ C +GTCVC+PGF G C+ H F
Sbjct: 947 CDRCQLGFFGFSIKG-----CRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNF 1001
Query: 608 ----------SCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAE 657
CP+CY VK + + +L E + QG D P L+ + +A
Sbjct: 1002 FLTADGTHCQQCPSCYALVKEEAAKLKARLTLTEGWL---QGSDCGSPWGPLDILLGEAP 1058
Query: 658 QALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVR 717
+ D+ + + GA + Q+ + + + +L L +A + ++
Sbjct: 1059 RG--DVYQGHHLLPGAREAFLEQMMSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLA 1116
Query: 718 DTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQ 777
D ++ + + + A L + IP + P + LA EA LA SH ++A+ +
Sbjct: 1117 DLEAVLESSEEEILHAAAILASLEIP-QEGPSQPTKWSHLATEARALARSHRDTATKIAA 1175
Query: 778 LTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQA 837
S + +L+ L +G V LE Q + A
Sbjct: 1176 TAWRALLASNTSYALLWNLL-----------EGRVALETQRDLEDRYQEVQAAQKALRTA 1224
Query: 838 EIEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQK 897
E + L + V A K +A+ L + K +K
Sbjct: 1225 VAEVLPEAESVLATVQQVGADTAPYLALLASPGALPQKSRAEDLGL-------KAKALEK 1277
Query: 898 NLGNWKE---EAQQLLQNGKSGREKSDQLLSR----ANLAKSRAQEALSMGNATFYEVES 950
+ +W+ EA + LQ + + L++ A A ++A ++ T +
Sbjct: 1278 TVASWQHMATEAARTLQTAAQATLRQTEPLTKLHQEARAALTQASSSVQAATVTVMGART 1337
Query: 951 ILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNG 1010
+L +L LQ K +A K S + ++D KT+QAER LG+AA + AK
Sbjct: 1338 LLADLEGMKLQFPRPKDQAALQRKADSVSDRLLADTRKKTKQAERMLGNAAPLSSSAKKK 1397
Query: 1011 AGEALEISSEIEQEIGSLNLEANVTADGALAM-EKGLASLKSEMREV-EGELERKELEFD 1068
EA ++ + + +L E A + + A+L+ ++V E R+ELE
Sbjct: 1398 GREAEVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQASQQVLASEARRQELE-- 1455
Query: 1069 TNMDAVQMVITEAQKVDTRAKNAGVTIQDTLNTLDGLLHLMG 1110
+ V +++ + + + ++++ + TL LL +G
Sbjct: 1456 ----EAERVGAGLSEMEQQIRESRISLEKDIETLSELLARLG 1493
Score = 115 bits (288), Expect = 2e-25
Identities = 62/148 (41%), Positives = 80/148 (54%), Gaps = 22/148 (14%)
Query: 53 CLNCNDNTDGIHCEKCKNGFYRH----RERDRCLPCNCNSKGSLSAR--CDN-SGRCSCK 105
CL C NT G HCE C+ GFY R D+C+PC+C+ +GS+S + CD +G+CSC
Sbjct: 831 CLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCL 890
Query: 106 PGVTGARCDRCLPGFHMLTDA-GCTQDQRLLDSKCDCDPAGI-AGPC--DAGRCVCKPAV 161
P VT C RC PGF L GC C C P G C G+C C+P V
Sbjct: 891 PHVTARDCSRCYPGFFDLQPGRGC--------RSCKCHPLGSQEDQCHPKTGQCTCRPGV 942
Query: 162 TGERCDRCRSGYYNLDGGNPEGCTQCFC 189
TG+ CDRC+ G++ G + +GC C C
Sbjct: 943 TGQACDRCQLGFF---GFSIKGCRACRC 967
Score = 74.3 bits (181), Expect = 6e-13
Identities = 49/152 (32%), Positives = 63/152 (41%), Gaps = 19/152 (12%)
Query: 53 CLNCNDNTDGIHCEKCKNGFYRHR-----ERDRCLPCNCNSKGSLSA--RCDN-SGRC-S 103
C +C G CE C +GF+ C C C+ +A CD SG C
Sbjct: 774 CTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLR 833
Query: 104 CKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAG---PCD--AGRCVCK 158
C TG C+ C GF+ A D+ + C C P G PCD G+C C
Sbjct: 834 CLHNTTGDHCEHCQEGFYGSALAPRPADKCM---PCSCHPQGSVSEQMPCDPVTGQCSCL 890
Query: 159 PAVTGERCDRCRSGYYNLDGGNPEGCTQCFCY 190
P VT C RC G+++L G GC C C+
Sbjct: 891 PHVTARDCSRCYPGFFDLQPG--RGCRSCKCH 920
Score = 73.2 bits (178), Expect = 1e-12
Identities = 45/149 (30%), Positives = 63/149 (42%), Gaps = 13/149 (8%)
Query: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQC 519
C C NG + P+ + C TG CE C + P+ G C PC C
Sbjct: 271 CKC-NGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC 329
Query: 520 NNNVDPSA-SGNCDRLTG---RCLKCIHNTAGIYCDQCKAGYFG-DPLAPNPADKCRACN 574
+ + R TG RC C +TAG +C++C+ ++ DP P C+ C+
Sbjct: 330 SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP-----CQPCD 384
Query: 575 CNPMGSEPVGCRSDGTCVCKPGFGGPNCE 603
C GS + C GTC CKP G C+
Sbjct: 385 CQSAGSLHLQCDDTGTCACKPTVTGWKCD 413
Score = 72.8 bits (177), Expect = 2e-12
Identities = 65/254 (25%), Positives = 83/254 (32%), Gaps = 41/254 (16%)
Query: 416 CNCQGGGA-CDPDTGD---CYSGDENPDIECADCPIGFYNDP------HDPRSCKPCPCH 465
C C G + C PD C +C C F + P C PC C
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 466 N-GFSCSVMPETEEVV-----CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC 519
C+ E C++C G CE C + ++ P PCQPC C
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFY-----HWDPRMPCQPCDC 385
Query: 520 NNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG 579
+ S CD TG C C G CD+C G+ CR C CNP G
Sbjct: 386 QSA--GSLHLQCDD-TGTCA-CKPTVTGWKCDRCLPGFHS-----LSEGGCRPCTCNPAG 436
Query: 580 SEPVGCRSDGTCVCKPGFGGPNCE-----------HGAFSCPACYNQVKIQMDQFMQQLQ 628
S G C CK G C+ H C +C+ ++ Q Q
Sbjct: 437 SLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVCASTAQFQ 496
Query: 629 RMEALISKAQGGDG 642
L QG +G
Sbjct: 497 VHHILSDFHQGAEG 510
Score = 64.3 bits (155), Expect = 6e-10
Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 8/98 (8%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCN 87
C C+ Q + + H +TG C G C++C+ GF+ + C C C+
Sbjct: 917 CKCHPLGSQ---EDQCHPKTGQ----CTCRPGVTGQACDRCQLGFFGFSIKG-CRACRCS 968
Query: 88 SKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTD 125
G+ SA+C +G C C+PG G +CDRC F + D
Sbjct: 969 PLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTAD 1006
Score = 40.4 bits (93), Expect = 0.009
Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 5/64 (7%)
Query: 541 CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGS-EPVGCRSDGTCVCKPGFGG 599
C G +C+ C GY + P C C CN G+ +P + G CVC G
Sbjct: 675 CPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGTCDP----NTGICVCSHHTEG 730
Query: 600 PNCE 603
P+CE
Sbjct: 731 PSCE 734
Score = 34.7 bits (78), Expect = 0.52
Identities = 25/90 (27%), Positives = 31/90 (34%), Gaps = 9/90 (10%)
Query: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDP---DTGDCYS 433
P QC C G GQ C C G+ S + C C C GA + G C
Sbjct: 931 PKTGQCTCRPGVTGQACDRCQLGFFGFSIK-----GCRACRCSPLGAASAQCHENGTCVC 985
Query: 434 GDENPDIECADCPIGFYNDPHDPRSCKPCP 463
+C C F+ D C+ CP
Sbjct: 986 RPGFEGYKCDRCHDNFFLTA-DGTHCQQCP 1014
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 358 bits (919), Expect = 2e-98
Identities = 235/646 (36%), Positives = 325/646 (50%), Gaps = 94/646 (14%)
Query: 26 EVCDCNGKSRQCIFDRELHRQ-----TGNGFR----CLNCNDNTDGIHCEKCKNGFYR-H 75
E C+C+ K++ C +D + +Q T FR C+NC NT GI+CE C +G+YR H
Sbjct: 325 EACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPH 384
Query: 76 R----ERDRCLPCNCNSKGSLSARC------------DNSGRCSCKPGVTGARCDRCLPG 119
+ E + C PCNC+ GSLS+ C G+C CK G TG +CDRC G
Sbjct: 385 KVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLG 444
Query: 120 FHMLTDAGCTQDQRLLDSKCDCDPAGIAG--PCDAGRCVCKPAVTGERCDRCRSGYYNLD 177
+ +D S C C+P G A PC G CVCK V G+ CDRC+ G+YNL
Sbjct: 445 Y---------KDYPTCVS-CGCNPVGSASDEPC-TGPCVCKENVEGKACDRCKPGFYNLK 493
Query: 178 GGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQ--- 234
NP GC++CFC+G S C SS + V ++ S + GW SP K+ Q
Sbjct: 494 EKNPRGCSECFCFGVSDVC-SSLSWPVGQVNS-----MSGWLVTDLI-SPRKIPSQQDAL 546
Query: 235 --RHQDVFSSA---QRLDPVYF-VAPAKFLGNQQVSYG----QSLSFDYRVDRGGRHPSA 284
RHQ ++ QRL P Y+ AP +LGN+ ++G ++S+D V+ + +
Sbjct: 547 GGRHQVSINNTAVMQRLAPKYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPVETVDSNLMS 606
Query: 285 H-DVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSN----NWSPQLSYFEYRRL 339
H DVI++G GL ++ + L + Y + P N + Q+ + +
Sbjct: 607 HADVIIKGNGLTLSTQ----AEGLSLQPYEEYLNVVRLVPENFQDFHSKRQIDRDQLMTV 662
Query: 340 LRNLTALRIRATYGEYSTGY--IDNVTL--ISARPVSGAPAPWVEQCICPVGYKGQFCQD 395
L N+T L IRA Y +++V+L S+ + A VE C CP GY G C+
Sbjct: 663 LANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVAADVEHCECPQGYTGTSCES 722
Query: 396 CASGYKR-DSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPD-IECADCPIGFYNDP 453
C SGY R D G G C PC C G A G C + N + C C GFY +P
Sbjct: 723 CLSGYYRVDGILFG--GICQPCECHGHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEP 780
Query: 454 H--DPRSCKPCPC-----HNGFSCSV-MPETEEVVCNNCPPGVTGARCELCADGYFGDPF 505
P C+PC C N FS + + + +EVVC+ C PG +GA CE CADGY+G+P
Sbjct: 781 SRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPT 840
Query: 506 GEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPN 565
P C PC C+ NVDPS +G+CD +TG CLKC+ NT G +C++C G++GD +
Sbjct: 841 V---PGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVT-- 895
Query: 566 PADKCRACNCNPMGSEPVGCRSD-GTCVCKPGFGGPNCE---HGAF 607
A CRAC C+ GS C + G C CKP G C+ HG +
Sbjct: 896 -AKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYY 940
Score = 230 bits (587), Expect = 5e-60
Identities = 262/1165 (22%), Positives = 448/1165 (38%), Gaps = 160/1165 (13%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCN 87
CDC C +TG C+ C +T G+ CE+C++G + + C CNC+
Sbjct: 998 CDCPHTQNTC------DPETGE---CV-CPPHTQGVKCEECEDGHWGYDAEVGCQACNCS 1047
Query: 88 SKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGI 146
GS RCD +G C CK G CD+C G+ D CDCD G
Sbjct: 1048 LVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDC----------VPCDCDLRGT 1097
Query: 147 AGPC------------DAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSA 194
+G + G C CK V G +C+ CR G + L NP GC+ CFC G S
Sbjct: 1098 SGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSH 1157
Query: 195 SCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVFSSAQ-----RLDPV 249
C +Y +T Q + + + + Q + +A R +P
Sbjct: 1158 LCSELEDYVRTPVTLGSDQPLLRVVSQSNLRGTTEGVYYQAPDFLLDAATVRQHIRAEPF 1217
Query: 250 YFVAPAKFLGNQQVSYGQSLSFD---YRVDRGGRHPSAHDVILEGAGLRITAPLMPLGKT 306
Y+ P +F G+Q ++YG L + Y +D G V+++G RI ++ +
Sbjct: 1218 YWRLPQQFQGDQLMAYGGKLKYSVAFYSLDGVGTSNFEPQVLIKGG--RIRKQVIYMDAP 1275
Query: 307 LP-CGLTKTYTFRLNEHPSNNW-------SPQLSYFEYRRLLRNLTALRIRATYGE-YST 357
P G+ + + E N W ++ ++ +L ++ + I+A+YG+
Sbjct: 1276 APENGVRQEQEVAMRE---NFWKYFNSVSEKPVTREDFMSVLSDIEYILIKASYGQGLQQ 1332
Query: 358 GYIDNVTLISARPV-----SGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGP--- 409
I ++++ R A +E C+CP G G CQDCA GY R G
Sbjct: 1333 SRISDISMEVGRKAEKLHPEEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRG 1392
Query: 410 ----FGTCIPCNCQG-GGACDPDTGDCYS-GDENPDIECADCPIGFYNDPHDPRS-CKPC 462
C+PC+C CDP+TG C + GD C C G+Y S C C
Sbjct: 1393 PRPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALC 1452
Query: 463 PCHNGFSCSVMPE-----TEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPC 517
C + S P + C+ C G G CE C+ Y+G+P P CQ C
Sbjct: 1453 ACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNP---QTPGGSCQKC 1509
Query: 518 QCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNP 577
CN + S G+CDR +G+C+ C +G+ CD+C +P C +C+
Sbjct: 1510 DCNPH--GSVHGDCDRTSGQCV-CRLGASGLRCDEC------EPRHILMETDCVSCDDEC 1560
Query: 578 MGSEPVGCRSDGTCVCKPGFGG----PNCEHGAFSCPACYNQVKIQMDQFMQQLQRMEAL 633
+G G V G P Y Q + + + L +++ L
Sbjct: 1561 VGVLLNDLDEIGDAVLSLNLTGIIPVPYGILSNLENTTKYLQESLLKENMQKDLGKIK-L 1619
Query: 634 ISKAQGGDGVVPD-TELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENSYQ 692
A+ D + T + Q+ +A + I +++Q A L + + ++ + Q
Sbjct: 1620 EGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIERLQMSITEIMEKTTLNQ 1679
Query: 693 SRLDDLKM---TVERVRALGSQYQN--RVRDTHRLITQMQLSLAESEASLGNTNIPASDH 747
+ +D + T++ ++ G+ ++RD +L L L +E L ++
Sbjct: 1680 TLDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQ----IQEN 1735
Query: 748 YVGP-NGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLV-----------RK 795
Y P + L + A+ + H E L RE E +++ L+ K
Sbjct: 1736 YQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDK 1795
Query: 796 ALH---------EGVGSGSGSPDGAVVQ--GLVEKLEKTKSLAQQLTREATQAEIEADRS 844
LH E + G G D A Q + + LE + +L + + D
Sbjct: 1796 KLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDL 1855
Query: 845 YQHS---------LRLLDSVSRLQGVSDQSFQ-VEEAKRIKQKADS-------LSSLVTR 887
H R D + Q ++D + +E + + A S + SL+
Sbjct: 1856 VMHMSQRNAVDLVYRAEDHAAEFQRLADVLYSGLENIRNVSLNATSAAYVHYNIQSLIEE 1915
Query: 888 HMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYE 947
+ + + + ++ L+ NGK+ ++S + L N SR +++ E
Sbjct: 1916 SEELARDAHRTVTETSLLSESLVSNGKAAVQRSSRFLKEGN-NLSRKLPGIAL------E 1968
Query: 948 VESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRA 1007
+ + F + E++ L I + + D KT++ + +A R
Sbjct: 1969 LSELRNKTNRFQENAVEITRQTNESLLILRAIPKGIRDKGAKTKELATSASQSAVSTLRD 2028
Query: 1008 KNG-AGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGE------- 1059
G + E L S+ + + +L + D +A LA K + E++
Sbjct: 2029 VAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMATL--LAGRKVKDVEIQANLLFDRLK 2086
Query: 1060 -LERKELEFDTNMDAVQMVITEAQK 1083
L+ E N+ ++++I++A+K
Sbjct: 2087 PLKMLEENLSRNLSEIKLLISQARK 2111
Score = 127 bits (320), Expect = 4e-29
Identities = 85/270 (31%), Positives = 115/270 (42%), Gaps = 63/270 (23%)
Query: 384 CPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG------GACDPDTGDCYSGDEN 437
C GY G +C+ CA GY + G +C+PC+C G G CD TG+C N
Sbjct: 819 CAPGYSGAWCERCADGYYGNPTVPGE--SCVPCDCSGNVDPSEAGHCDSVTGECLKCLGN 876
Query: 438 PD-IECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
D C C GFY D ++C+ C CH S S + E +C+ C P VTG +C+ C
Sbjct: 877 TDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCD-CKPNVTGQQCDQC 935
Query: 497 ADGYFGDPFGEHGPVRPCQPCQCN-----------------------NNVDPSASG---- 529
GY+G G HG C+PC C+ D A G
Sbjct: 936 LHGYYGLDSG-HG----CRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAY 990
Query: 530 ---------------NCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACN 574
CD TG C+ C +T G+ C++C+ G++G C+ACN
Sbjct: 991 QDGSCTPCDCPHTQNTCDPETGECV-CPPHTQGVKCEECEDGHWGYDAEVG----CQACN 1045
Query: 575 CNPMGSEPVGCR-SDGTCVCKPGFGGPNCE 603
C+ +GS C G C CK FGG C+
Sbjct: 1046 CSLVGSTHHRCDVVTGHCQCKSKFGGRACD 1075
Score = 114 bits (284), Expect = 7e-25
Identities = 56/162 (34%), Positives = 74/162 (45%), Gaps = 17/162 (10%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCN 87
C+C+ K H +TG +C N G C++C +G+Y C PCNC+
Sbjct: 902 CECHVKGSHSAV---CHLETG----LCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCS 954
Query: 88 SKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA 147
GS+S C + G+C C PGV G RCDRC GF+ D CT CDC
Sbjct: 955 VAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCT--------PCDCPHTQNT 1006
Query: 148 GPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
+ G CVC P G +C+ C G++ D GC C C
Sbjct: 1007 CDPETGECVCPPHTQGVKCEECEDGHWGYDA--EVGCQACNC 1046
Score = 111 bits (278), Expect = 3e-24
Identities = 92/311 (29%), Positives = 116/311 (37%), Gaps = 51/311 (16%)
Query: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDP---DTGDCYSGDENP 438
C C GQ C C GY + G C PCNC G+ D G C+
Sbjct: 921 CDCKPNVTGQQCDQCLHGYYGLDSGHG----CRPCNCSVAGSVSDGCTDEGQCHCVPGVA 976
Query: 439 DIECADCPIGFYNDPHDPRSCKPCPC-HNGFSCSVMPETEEVVCNNCPPGVTGARCELCA 497
C C GFY + SC PC C H +C PET E VC PP G +CE C
Sbjct: 977 GKRCDRCAHGFY--AYQDGSCTPCDCPHTQNTCD--PETGECVC---PPHTQGVKCEECE 1029
Query: 498 DGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGY 557
DG++G E G CQ C C+ + S CD +TG C +C G CDQC GY
Sbjct: 1030 DGHWGYD-AEVG----CQACNCS--LVGSTHHRCDVVTGHC-QCKSKFGGRACDQCSLGY 1081
Query: 558 FGDPLAPNPADKCRACNCNPMGSEPVGCRSD----------GTCVCKPGFGGP---NCEH 604
P C C+C+ G+ C + G C CK GP C
Sbjct: 1082 RDFP-------DCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECRE 1134
Query: 605 GAFS--------CPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQA 656
G F+ C C+ + ++ R + Q VV + L G +
Sbjct: 1135 GTFALRADNPLGCSPCFCSGLSHLCSELEDYVRTPVTLGSDQPLLRVVSQSNLRGTTEGV 1194
Query: 657 EQALQDILRDA 667
D L DA
Sbjct: 1195 YYQAPDFLLDA 1205
Score = 79.3 bits (194), Expect = 2e-14
Identities = 52/182 (28%), Positives = 70/182 (38%), Gaps = 31/182 (17%)
Query: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQC 519
C C+ S ET + + C G C C GY P+ G C+ C C
Sbjct: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329
Query: 520 NNNV-----DPSASGNCDRLT--------GRCLKCIHNTAGIYCDQCKAGYF-GDPLAPN 565
+N D S + L G C+ C+ NT GI C+ C GY+ ++P
Sbjct: 330 HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPY 389
Query: 566 PADKCRACNCNPMGSEPVGCRSD------------GTCVCKPGFGGPNCEH---GAFSCP 610
+ CR CNC+P+GS C D G C CK G+ G C+ G P
Sbjct: 390 EDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYP 449
Query: 611 AC 612
C
Sbjct: 450 TC 451
Score = 77.4 bits (189), Expect = 7e-14
Identities = 60/210 (28%), Positives = 86/210 (40%), Gaps = 38/210 (18%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNC-QGGGACDPDTGDCYSGDENPD 439
QC C G G+ C CA G+ G+C PC+C CDP+TG+C
Sbjct: 968 QCHCVPGVAGKRCDRCAHGFYAYQD-----GSCTPCDCPHTQNTCDPETGECVCPPHTQG 1022
Query: 440 IECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETE---EVVCNN--CPPGVTGARCE 494
++C +C G + + C+ C +CS++ T +VV + C G C+
Sbjct: 1023 VKCEECEDGHWGYDAEV-GCQAC------NCSLVGSTHHRCDVVTGHCQCKSKFGGRACD 1075
Query: 495 LCADGYFGDPFGEHGPVRPCQPCQCN--------NNVDPSASGNCDRLTGRCLKCIHNTA 546
C+ GY P C PC C+ N++ G C TG C C N
Sbjct: 1076 QCSLGYRDFP--------DCVPCDCDLRGTSGDACNLEQGLCG-CVEETGAC-PCKENVF 1125
Query: 547 GIYCDQCKAGYFGDPLAPNPADKCRACNCN 576
G C++C+ G F A NP C C C+
Sbjct: 1126 GPQCNECREGTFA-LRADNPLG-CSPCFCS 1153
Score = 72.8 bits (177), Expect = 2e-12
Identities = 65/247 (26%), Positives = 86/247 (34%), Gaps = 69/247 (27%)
Query: 377 PWVE-----QCICPVGYKGQFCQDCASGYKRDSARLGPF---GTCIPCNC---------- 418
PW E QC C G+ C C GY + R G TC CNC
Sbjct: 280 PWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYD 339
Query: 419 ----------------QGGGACDPDTGDCYSGDENPDIECADCPIGFYN----DPHDPRS 458
+GGG C +C I C C G+Y P++
Sbjct: 340 ESVAKQKKSLNTAGQFRGGGVCI----NCL--QNTMGINCETCIDGYYRPHKVSPYEDEP 393
Query: 459 CKPCPCHNGFSCSVMPETEEVVCN----------NCPPGVTGARCELCADGYFGDPFGEH 508
C+PC C S S + +++ + C G TG +C+ C GY P
Sbjct: 394 CRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYP---- 449
Query: 509 GPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPAD 568
C C CN P S + + TG C+ C N G CD+CK G++ L
Sbjct: 450 ----TCVSCGCN----PVGSASDEPCTGPCV-CKENVEGKACDRCKPGFYN--LKEKNPR 498
Query: 569 KCRACNC 575
C C C
Sbjct: 499 GCSECFC 505
Score = 38.9 bits (89), Expect = 0.027
Identities = 29/113 (25%), Positives = 40/113 (35%), Gaps = 26/113 (23%)
Query: 101 RCSCKPGVTGARCDRCLPGFHM------LTDAG--------------CTQDQRLLDSKCD 140
+C C+ G C+RC PG+H +G C D+ + K
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
Query: 141 CDPAGIAGPCDAGRCV-CKPAVTGERCDRCRSGYYNLDGGNP---EGCTQCFC 189
+ AG G C+ C G C+ C GYY +P E C C C
Sbjct: 349 LNTAGQFR--GGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNC 399
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 313 bits (802), Expect = 6e-85
Identities = 230/705 (32%), Positives = 310/705 (43%), Gaps = 150/705 (21%)
Query: 26 EVCDCNGKSRQCIFDRELHRQT----------GNGFRCLNCNDNTDGIHCEKCKNGFYRH 75
E C+C+GK+ +C +D + R+ G G C+NC NT GI+CE C +GF+R
Sbjct: 342 EACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGV-CINCTQNTAGINCETCTDGFFRP 400
Query: 76 RERDR-----CLPCNCNSKGSLSARCDNS----------GRCSCKPGVTGARCDRCLPGF 120
+ C PC+C+ GSL+ C G C CK G G CDRC G+
Sbjct: 401 KGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460
Query: 121 HMLTDAGCTQDQRLLDSKCDCDPAGIAG--PCDAGRCVCKPAVTGERCDRCRSGYYNLDG 178
D C+C G PC G C+CK V G C RC+SG++NL
Sbjct: 461 TGYPDC----------KACNCSGLGSKNEDPC-FGPCICKENVEGGDCSRCKSGFFNLQE 509
Query: 179 GNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNG----SPAKLQWSQ 234
N +GC +CFC G S C+SS ++ KI QD+ GW G +P +
Sbjct: 510 DNWKGCDECFCSGVSNRCQSSY-WTYGKI-----QDMSGWYLTDLPGRIRVAPQQDDLDS 563
Query: 235 RHQDVFSSAQRLDPV----YFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDV--- 287
Q S+A+ + Y+ APA +LGN+ + G L+F D V
Sbjct: 564 PQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQL 623
Query: 288 --ILEGAGLRITAP-----LMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRR-- 338
ILEG L I+ L P + L K +F ++ ++F RR
Sbjct: 624 MIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHG----------THFPVRRKE 673
Query: 339 ---LLRNLTALRIRATY--GEYSTGYIDNVTLISA--RPVSGAPAPWVEQCICPVGYKGQ 391
+L NL + ++ TY G + + +V L SA P G+ A VE C CP GY G
Sbjct: 674 FMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGS 733
Query: 392 FCQDCASGYKRDSARLGPFGTCIPCNCQGGG-ACDPDTGDCYS-GDENPDIECADCPIGF 449
C+ C ++R + + G C PC C G +CD TG+C + D C C GF
Sbjct: 734 SCESCWPRHRRVNGTIFG-GICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGF 792
Query: 450 YNDPHDPRS--CKPCPC-----HNGFSCSV-MPETEEVVCNNCPPGVTGARCELCADGYF 501
Y +P S C+PC C N FS + + + ++C+ CP G TG RCE CA+GYF
Sbjct: 793 YGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYF 852
Query: 502 GDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDP 561
G P G CQPCQCN+N+D S G+CD L+G CL C T G YC+ C GYFGD
Sbjct: 853 GQPSVPGGS---CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDA 909
Query: 562 L-APN--------------------------------PADKCRA-------------CNC 575
+ A N DKC+A CNC
Sbjct: 910 VDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNC 969
Query: 576 NPMGSEPVGCRSDGTCVCKPGFGGPNCE---HGAFS-----CPAC 612
N GS+ C G C C+PG G C+ HG F+ C AC
Sbjct: 970 NSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTAC 1014
Score = 240 bits (612), Expect = 6e-63
Identities = 280/1159 (24%), Positives = 454/1159 (39%), Gaps = 188/1159 (16%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCN 87
C+C+ C +TG RC+ C NT G C KC + H C CNC+
Sbjct: 1014 CECSHLGNNC------DPKTG---RCI-CPPNTIGEKCSKCAPNTWGHSITTGCKACNCS 1063
Query: 88 SKGSLSARCD-NSGRCSCKPGVTGARCDRCLPG------------FHMLTDAGCTQDQRL 134
+ GSL +C+ N+G+C+C P +GA+C C G F TDA +
Sbjct: 1064 TVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSET- 1122
Query: 135 LDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSA 194
KC C G+C CK V G CDRCR G + LD NP GC+ C+C+G +
Sbjct: 1123 --KKCSCSD-------QTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTT 1173
Query: 195 SCRSSAEYSVHKITSTFHQDV-----DGWKAVQRNGSPAKLQWSQRHQDVFSSAQRLDPV 249
C + +T Q + + + G + H D+ L+P
Sbjct: 1174 QCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPF 1233
Query: 250 YFVAPAKFLGNQQVSYGQSLS----FDYRVDRGGRHPSAHDVILEGAGLRITAPLMPLGK 305
Y+ P +F G + ++YG L F+ R + G + +I G + +
Sbjct: 1234 YWKLPEQFEGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAA 1293
Query: 306 TLPCGLTKTYTFRLNEHPSNNWSPQ------LSYFEYRRLLRNLTALRIRATYGEYST-G 358
L LT+ + + E + ++ ++ +L ++ + I+ATYG +
Sbjct: 1294 PLIGQLTR-HEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQS 1352
Query: 359 YIDNVTLISARPVSGA----PAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCI 414
I +++ A G PA +E+C CP+GY G C+ C G+ R ++
Sbjct: 1353 RISEISMEVAEQGRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQ-------- 1404
Query: 415 PCNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMP 474
GG P G +C PC C NG S P
Sbjct: 1405 ----PGGRTPGPTLG----------------------------TCVPCQC-NGHSSLCDP 1431
Query: 475 ETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC-----NNNVDPS--A 527
ET +C NC G CE CA GY+G G CQ C C +NN PS A
Sbjct: 1432 ETS--ICQNCQHHTAGDFCERCALGYYGIV---KGLPNDCQQCACPLISSSNNFSPSCVA 1486
Query: 528 SGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRS 587
G D RC C G YC++C GY G P NP C+ C C+P GS PV C
Sbjct: 1487 EGLDDY---RCTACPRGYEGQYCERCAPGYTGSP--GNPGGSCQECECDPYGSLPVPCDP 1541
Query: 588 -DGTCVCKPGFGGPNCE-------HGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQ- 638
G C C+PG G C+ + C C ++ + L R+E ++
Sbjct: 1542 VTGFCTCRPGATGRKCDGCKHWHAREGWECVFCGDEC---TGLLLGDLARLEQMVMSINL 1598
Query: 639 GGDGVVPDTELEGRMQQAEQALQDIL-------RDAQISEGASRSLGLQLAKVRSQENSY 691
G P L G ++ Q L+ +L R Q++EG +L ++ ++ ++
Sbjct: 1599 TGPLPAPYKMLYG-LENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKV 1657
Query: 692 ----QSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDH 747
+ D + T R ++LG + RD + + + L E +LG + +
Sbjct: 1658 TADGEQTGQDAERTNTRAKSLGEFIKELARDA-EAVNEKAIKLNE---TLGTRDEAFERN 1713
Query: 748 YVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGS 807
G K + Q L ++E+ +++ + ++ L V+K E G
Sbjct: 1714 LEGLQ--KEIDQMIKELRRKNLET---QKEIAEDELVAAEALLKKVKKLFGESRGENE-- 1766
Query: 808 PDGAVVQGLVEKLEKTKSL---AQQLTREATQAEIEADRSYQHSLRLLDSV-SRLQGVSD 863
+ + L EKL K+ A L REAT EA+R + + + + ++ + + V
Sbjct: 1767 ---EMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVES 1823
Query: 864 QSFQVE----EAKRIKQKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREK 919
Q+E E I +A+ L+ + +D + Q L EE + + S K
Sbjct: 1824 GKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDD-LSQEIK 1882
Query: 920 SDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYI 979
+L + + A+S A A + ++L + + + N A A K S I
Sbjct: 1883 DRKLAEKVSQAESHA--------AQLNDSSAVLDGILD---EAKNISFNATAAFKAYSNI 1931
Query: 980 SQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE--IEQEIGSLNLEANVTAD 1037
+ +A ++A+ A +A + G L+ ++ +++ LN EA A+
Sbjct: 1932 KDYIDEAEKVAKEAK----DLAHEATKLATGPRGLLKEDAKGCLQKSFRILN-EAKKLAN 1986
Query: 1038 GALAMEKGLASLKSEMREVE---GELERKELEFDTNMDAV--------QMVITEAQKVDT 1086
E L LK+ + + G+L R + + A+ Q V +A++ +
Sbjct: 1987 DVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDKARQAND 2046
Query: 1087 RAKNAGVTIQDTLNTLDGL 1105
AK+ I + LDGL
Sbjct: 2047 TAKDVLAQITELHQNLDGL 2065
Score = 127 bits (319), Expect = 6e-29
Identities = 82/238 (34%), Positives = 103/238 (43%), Gaps = 30/238 (12%)
Query: 383 ICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDENP 438
IC G G++C+ CA GY D+ C PC C GG+ C TG C
Sbjct: 888 ICKPGTTGRYCELCADGYFGDAVDAK---NCQPCRCNAGGSFSEVCHSQTGQCECRANVQ 944
Query: 439 DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCAD 498
C C G + R C PC C N F E C C PGVTG +C+ CA
Sbjct: 945 GQRCDKCKAGTFG-LQSARGCVPCNC-NSFGSKSFDCEESGQCW-CQPGVTGKKCDRCAH 1001
Query: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
GYF F E G C C+C++ NCD TGRC+ C NT G C +C +
Sbjct: 1002 GYFN--FQEGG----CTACECSH-----LGNNCDPKTGRCI-CPPNTIGEKCSKCAPNTW 1049
Query: 559 GDPLAPNPADKCRACNCNPMGSEPVGCR-SDGTCVCKPGFGG---PNCEHGAFSCPAC 612
G + C+ACNC+ +GS C + G C C P F G C G ++ P C
Sbjct: 1050 GHSITTG----CKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRC 1103
Score = 120 bits (300), Expect = 9e-27
Identities = 64/182 (35%), Positives = 80/182 (43%), Gaps = 17/182 (9%)
Query: 8 CCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEK 67
C LC A + C CN F H QTG C N G C+K
Sbjct: 898 CELCADGYFGDAVDAKNCQPCRCNAGGS---FSEVCHSQTGQ----CECRANVQGQRCDK 950
Query: 68 CKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAG 127
CK G + + C+PCNCNS GS S C+ SG+C C+PGVTG +CDRC G+ + G
Sbjct: 951 CKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGG 1010
Query: 128 CTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQC 187
CT C+C G GRC+C P GE+C +C + GC C
Sbjct: 1011 CT--------ACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWG--HSITTGCKAC 1060
Query: 188 FC 189
C
Sbjct: 1061 NC 1062
Score = 95.9 bits (237), Expect = 2e-19
Identities = 72/260 (27%), Positives = 105/260 (40%), Gaps = 55/260 (21%)
Query: 381 QCICPVGYKGQFCQDCASG-YKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGD 435
QC C +GQ C C +G + SAR C+PCNC G+ C+ ++G C+
Sbjct: 936 QCECRANVQGQRCDKCKAGTFGLQSAR-----GCVPCNCNSFGSKSFDCE-ESGQCWCQP 989
Query: 436 ENPDIECADCPIGFYNDPHDPRSCKPCPC-HNGFSCSVMPETEEVVCNNCPPGVTGARCE 494
+C C G++N C C C H G +C P+T + CPP G +C
Sbjct: 990 GVTGKKCDRCAHGYFN--FQEGGCTACECSHLGNNCD--PKTGRCI---CPPNTIGEKCS 1042
Query: 495 LCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCK 554
CA +G H C+ C C + S C+ TG+C C +G C +C
Sbjct: 1043 KCAPNTWG-----HSITTGCKACNC--STVGSLDFQCNVNTGQC-NCHPKFSGAKCTECS 1094
Query: 555 AGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD----------GTCVCKPGFGGPNCEH 604
G++ P +C C+C G++ C S+ G C CK G +C+
Sbjct: 1095 RGHWNYP-------RCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDR 1147
Query: 605 ---GAF--------SCPACY 613
G F C +CY
Sbjct: 1148 CRPGKFGLDAKNPLGCSSCY 1167
Score = 83.6 bits (205), Expect = 1e-15
Identities = 61/203 (30%), Positives = 77/203 (37%), Gaps = 26/203 (12%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPD 439
QC C G G+ C CA GY G C C C G CDP TG C
Sbjct: 984 QCWCQPGVTGKKCDRCAHGYFNFQE-----GGCTACECSHLGNNCDPKTGRCICPPNTIG 1038
Query: 440 IECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADG 499
+C+ C + CK C C S CN C P +GA+C C+ G
Sbjct: 1039 EKCSKCAPNTWGHSITT-GCKACNCSTVGSLDFQCNVNTGQCN-CHPKFSGAKCTECSRG 1096
Query: 500 YFGDPFGEHGPVRPCQPCQC-------NNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQ 552
++ P C C C + +C TG+C C N GI+CD+
Sbjct: 1097 HWNYP--------RCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCT-CKVNVEGIHCDR 1147
Query: 553 CKAGYFGDPLAPNPADKCRACNC 575
C+ G FG A NP C +C C
Sbjct: 1148 CRPGKFGLD-AKNPLG-CSSCYC 1168
Score = 77.8 bits (190), Expect = 5e-14
Identities = 53/184 (28%), Positives = 76/184 (41%), Gaps = 34/184 (18%)
Query: 462 CPCH-NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQ 518
C C+ + +C + P T + C C G C+ C G+ P+ G C+ C
Sbjct: 287 CICYGHARACPLDPATNKSRCE-CEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACN 345
Query: 519 CNNNVDPSA-SGNCDRLT------------GRCLKCIHNTAGIYCDQCKAGYFGDP-LAP 564
C+ + N R G C+ C NTAGI C+ C G+F ++P
Sbjct: 346 CHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSP 405
Query: 565 NPADKCRACNCNPMGSEPVGCRSD----------GTCVCKPGFGGPNCEH------GAFS 608
N C+ C+C+P+GS C D G+C CK GFGG +C+ G
Sbjct: 406 NYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD 465
Query: 609 CPAC 612
C AC
Sbjct: 466 CKAC 469
Score = 75.5 bits (184), Expect = 3e-13
Identities = 66/237 (27%), Positives = 87/237 (36%), Gaps = 50/237 (21%)
Query: 375 PAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGT---CIPCNCQG-GGACDPDT-- 428
PA +C C G C C G+ + R G F T C CNC G C D
Sbjct: 300 PATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENV 359
Query: 429 ----------------GDCYSGDEN-PDIECADCPIGFYN----DPHDPRSCKPCPCHNG 467
G C + +N I C C GF+ P+ PR C+PC C
Sbjct: 360 ARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPI 419
Query: 468 FSCSVMPETEEVVCN--------NCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC 519
S + + +E +C G G C+ CA GY G P C+ C C
Sbjct: 420 GSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYP--------DCKACNC 471
Query: 520 NNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCN 576
+ S N D G C+ C N G C +CK+G+F L + C C C+
Sbjct: 472 SG----LGSKNEDPCFGPCI-CKENVEGGDCSRCKSGFFN--LQEDNWKGCDECFCS 521
Score = 44.3 bits (103), Expect = 7e-04
Identities = 31/117 (26%), Positives = 41/117 (35%), Gaps = 28/117 (23%)
Query: 98 NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCD-CDPAGIAGPC------ 150
N RC C+ G CD+C PGFH T L ++C+ C+ G A C
Sbjct: 303 NKSRCECEHNTCGDSCDQCCPGFHQKPWRAGT---FLTKTECEACNCHGKAEECYYDENV 359
Query: 151 --------------DAGRCV-CKPAVTGERCDRCRSGYYNLDG---GNPEGCTQCFC 189
G C+ C G C+ C G++ G P C C C
Sbjct: 360 ARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHC 416
Score = 35.0 bits (79), Expect = 0.39
Identities = 20/80 (25%), Positives = 31/80 (38%), Gaps = 19/80 (23%)
Query: 9 CLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKC 68
C CF A S + C C+ ++ QC C N +GIHC++C
Sbjct: 1106 CDCFLPGTDATTCDSETKKCSCSDQTGQC-----------------TCKVNVEGIHCDRC 1148
Query: 69 KNGFYRHRERD--RCLPCNC 86
+ G + ++ C C C
Sbjct: 1149 RPGKFGLDAKNPLGCSSCYC 1168
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 313 bits (802), Expect = 6e-85
Identities = 230/705 (32%), Positives = 310/705 (43%), Gaps = 150/705 (21%)
Query: 26 EVCDCNGKSRQCIFDRELHRQT----------GNGFRCLNCNDNTDGIHCEKCKNGFYRH 75
E C+C+GK+ +C +D + R+ G G C+NC NT GI+CE C +GF+R
Sbjct: 342 EACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGV-CINCTQNTAGINCETCTDGFFRP 400
Query: 76 RERDR-----CLPCNCNSKGSLSARCDNS----------GRCSCKPGVTGARCDRCLPGF 120
+ C PC+C+ GSL+ C G C CK G G CDRC G+
Sbjct: 401 KGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460
Query: 121 HMLTDAGCTQDQRLLDSKCDCDPAGIAG--PCDAGRCVCKPAVTGERCDRCRSGYYNLDG 178
D C+C G PC G C+CK V G C RC+SG++NL
Sbjct: 461 TGYPDC----------KACNCSGLGSKNEDPC-FGPCICKENVEGGDCSRCKSGFFNLQE 509
Query: 179 GNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNG----SPAKLQWSQ 234
N +GC +CFC G S C+SS ++ KI QD+ GW G +P +
Sbjct: 510 DNWKGCDECFCSGVSNRCQSSY-WTYGKI-----QDMSGWYLTDLPGRIRVAPQQDDLDS 563
Query: 235 RHQDVFSSAQRLDPV----YFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDV--- 287
Q S+A+ + Y+ APA +LGN+ + G L+F D V
Sbjct: 564 PQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQL 623
Query: 288 --ILEGAGLRITAP-----LMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRR-- 338
ILEG L I+ L P + L K +F ++ ++F RR
Sbjct: 624 MIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHG----------THFPVRRKE 673
Query: 339 ---LLRNLTALRIRATY--GEYSTGYIDNVTLISA--RPVSGAPAPWVEQCICPVGYKGQ 391
+L NL + ++ TY G + + +V L SA P G+ A VE C CP GY G
Sbjct: 674 FMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGS 733
Query: 392 FCQDCASGYKRDSARLGPFGTCIPCNCQGGG-ACDPDTGDCYS-GDENPDIECADCPIGF 449
C+ C ++R + + G C PC C G +CD TG+C + D C C GF
Sbjct: 734 SCESCWPRHRRVNGTIFG-GICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGF 792
Query: 450 YNDPHDPRS--CKPCPC-----HNGFSCSV-MPETEEVVCNNCPPGVTGARCELCADGYF 501
Y +P S C+PC C N FS + + + ++C+ CP G TG RCE CA+GYF
Sbjct: 793 YGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYF 852
Query: 502 GDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDP 561
G P G CQPCQCN+N+D S G+CD L+G CL C T G YC+ C GYFGD
Sbjct: 853 GQPSVPGGS---CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDA 909
Query: 562 L-APN--------------------------------PADKCRA-------------CNC 575
+ A N DKC+A CNC
Sbjct: 910 VDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNC 969
Query: 576 NPMGSEPVGCRSDGTCVCKPGFGGPNCE---HGAFS-----CPAC 612
N GS+ C G C C+PG G C+ HG F+ C AC
Sbjct: 970 NSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTAC 1014
Score = 240 bits (612), Expect = 6e-63
Identities = 280/1159 (24%), Positives = 454/1159 (39%), Gaps = 188/1159 (16%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCN 87
C+C+ C +TG RC+ C NT G C KC + H C CNC+
Sbjct: 1014 CECSHLGNNC------DPKTG---RCI-CPPNTIGEKCSKCAPNTWGHSITTGCKACNCS 1063
Query: 88 SKGSLSARCD-NSGRCSCKPGVTGARCDRCLPG------------FHMLTDAGCTQDQRL 134
+ GSL +C+ N+G+C+C P +GA+C C G F TDA +
Sbjct: 1064 TVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSET- 1122
Query: 135 LDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSA 194
KC C G+C CK V G CDRCR G + LD NP GC+ C+C+G +
Sbjct: 1123 --KKCSCSD-------QTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTT 1173
Query: 195 SCRSSAEYSVHKITSTFHQDV-----DGWKAVQRNGSPAKLQWSQRHQDVFSSAQRLDPV 249
C + +T Q + + + G + H D+ L+P
Sbjct: 1174 QCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPF 1233
Query: 250 YFVAPAKFLGNQQVSYGQSLS----FDYRVDRGGRHPSAHDVILEGAGLRITAPLMPLGK 305
Y+ P +F G + ++YG L F+ R + G + +I G + +
Sbjct: 1234 YWKLPEQFEGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAA 1293
Query: 306 TLPCGLTKTYTFRLNEHPSNNWSPQ------LSYFEYRRLLRNLTALRIRATYGEYST-G 358
L LT+ + + E + ++ ++ +L ++ + I+ATYG +
Sbjct: 1294 PLIGQLTR-HEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQS 1352
Query: 359 YIDNVTLISARPVSGA----PAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCI 414
I +++ A G PA +E+C CP+GY G C+ C G+ R ++
Sbjct: 1353 RISEISMEVAEQGRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQ-------- 1404
Query: 415 PCNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMP 474
GG P G +C PC C NG S P
Sbjct: 1405 ----PGGRTPGPTLG----------------------------TCVPCQC-NGHSSLCDP 1431
Query: 475 ETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC-----NNNVDPS--A 527
ET +C NC G CE CA GY+G G CQ C C +NN PS A
Sbjct: 1432 ETS--ICQNCQHHTAGDFCERCALGYYGIV---KGLPNDCQQCACPLISSSNNFSPSCVA 1486
Query: 528 SGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRS 587
G D RC C G YC++C GY G P NP C+ C C+P GS PV C
Sbjct: 1487 EGLDDY---RCTACPRGYEGQYCERCAPGYTGSP--GNPGGSCQECECDPYGSLPVPCDP 1541
Query: 588 -DGTCVCKPGFGGPNCE-------HGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQ- 638
G C C+PG G C+ + C C ++ + L R+E ++
Sbjct: 1542 VTGFCTCRPGATGRKCDGCKHWHAREGWECVFCGDEC---TGLLLGDLARLEQMVMSINL 1598
Query: 639 GGDGVVPDTELEGRMQQAEQALQDIL-------RDAQISEGASRSLGLQLAKVRSQENSY 691
G P L G ++ Q L+ +L R Q++EG +L ++ ++ ++
Sbjct: 1599 TGPLPAPYKMLYG-LENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKV 1657
Query: 692 ----QSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDH 747
+ D + T R ++LG + RD + + + L E +LG + +
Sbjct: 1658 TADGEQTGQDAERTNTRAKSLGEFIKELARDA-EAVNEKAIKLNE---TLGTRDEAFERN 1713
Query: 748 YVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGS 807
G K + Q L ++E+ +++ + ++ L V+K E G
Sbjct: 1714 LEGLQ--KEIDQMIKELRRKNLET---QKEIAEDELVAAEALLKKVKKLFGESRGENE-- 1766
Query: 808 PDGAVVQGLVEKLEKTKSL---AQQLTREATQAEIEADRSYQHSLRLLDSV-SRLQGVSD 863
+ + L EKL K+ A L REAT EA+R + + + + ++ + + V
Sbjct: 1767 ---EMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVES 1823
Query: 864 QSFQVE----EAKRIKQKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREK 919
Q+E E I +A+ L+ + +D + Q L EE + + S K
Sbjct: 1824 GKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDD-LSQEIK 1882
Query: 920 SDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYI 979
+L + + A+S A A + ++L + + + N A A K S I
Sbjct: 1883 DRKLAEKVSQAESHA--------AQLNDSSAVLDGILD---EAKNISFNATAAFKAYSNI 1931
Query: 980 SQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSE--IEQEIGSLNLEANVTAD 1037
+ +A ++A+ A +A + G L+ ++ +++ LN EA A+
Sbjct: 1932 KDYIDEAEKVAKEAK----DLAHEATKLATGPRGLLKEDAKGCLQKSFRILN-EAKKLAN 1986
Query: 1038 GALAMEKGLASLKSEMREVE---GELERKELEFDTNMDAV--------QMVITEAQKVDT 1086
E L LK+ + + G+L R + + A+ Q V +A++ +
Sbjct: 1987 DVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDKARQAND 2046
Query: 1087 RAKNAGVTIQDTLNTLDGL 1105
AK+ I + LDGL
Sbjct: 2047 TAKDVLAQITELHQNLDGL 2065
Score = 127 bits (319), Expect = 6e-29
Identities = 82/238 (34%), Positives = 103/238 (43%), Gaps = 30/238 (12%)
Query: 383 ICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDENP 438
IC G G++C+ CA GY D+ C PC C GG+ C TG C
Sbjct: 888 ICKPGTTGRYCELCADGYFGDAVDAK---NCQPCRCNAGGSFSEVCHSQTGQCECRANVQ 944
Query: 439 DIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCAD 498
C C G + R C PC C N F E C C PGVTG +C+ CA
Sbjct: 945 GQRCDKCKAGTFG-LQSARGCVPCNC-NSFGSKSFDCEESGQCW-CQPGVTGKKCDRCAH 1001
Query: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
GYF F E G C C+C++ NCD TGRC+ C NT G C +C +
Sbjct: 1002 GYFN--FQEGG----CTACECSH-----LGNNCDPKTGRCI-CPPNTIGEKCSKCAPNTW 1049
Query: 559 GDPLAPNPADKCRACNCNPMGSEPVGCR-SDGTCVCKPGFGG---PNCEHGAFSCPAC 612
G + C+ACNC+ +GS C + G C C P F G C G ++ P C
Sbjct: 1050 GHSITTG----CKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRC 1103
Score = 120 bits (300), Expect = 9e-27
Identities = 64/182 (35%), Positives = 80/182 (43%), Gaps = 17/182 (9%)
Query: 8 CCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEK 67
C LC A + C CN F H QTG C N G C+K
Sbjct: 898 CELCADGYFGDAVDAKNCQPCRCNAGGS---FSEVCHSQTGQ----CECRANVQGQRCDK 950
Query: 68 CKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAG 127
CK G + + C+PCNCNS GS S C+ SG+C C+PGVTG +CDRC G+ + G
Sbjct: 951 CKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGG 1010
Query: 128 CTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQC 187
CT C+C G GRC+C P GE+C +C + GC C
Sbjct: 1011 CT--------ACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWG--HSITTGCKAC 1060
Query: 188 FC 189
C
Sbjct: 1061 NC 1062
Score = 95.9 bits (237), Expect = 2e-19
Identities = 72/260 (27%), Positives = 105/260 (40%), Gaps = 55/260 (21%)
Query: 381 QCICPVGYKGQFCQDCASG-YKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGD 435
QC C +GQ C C +G + SAR C+PCNC G+ C+ ++G C+
Sbjct: 936 QCECRANVQGQRCDKCKAGTFGLQSAR-----GCVPCNCNSFGSKSFDCE-ESGQCWCQP 989
Query: 436 ENPDIECADCPIGFYNDPHDPRSCKPCPC-HNGFSCSVMPETEEVVCNNCPPGVTGARCE 494
+C C G++N C C C H G +C P+T + CPP G +C
Sbjct: 990 GVTGKKCDRCAHGYFN--FQEGGCTACECSHLGNNCD--PKTGRCI---CPPNTIGEKCS 1042
Query: 495 LCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCK 554
CA +G H C+ C C + S C+ TG+C C +G C +C
Sbjct: 1043 KCAPNTWG-----HSITTGCKACNC--STVGSLDFQCNVNTGQC-NCHPKFSGAKCTECS 1094
Query: 555 AGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD----------GTCVCKPGFGGPNCEH 604
G++ P +C C+C G++ C S+ G C CK G +C+
Sbjct: 1095 RGHWNYP-------RCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDR 1147
Query: 605 ---GAF--------SCPACY 613
G F C +CY
Sbjct: 1148 CRPGKFGLDAKNPLGCSSCY 1167
Score = 83.6 bits (205), Expect = 1e-15
Identities = 61/203 (30%), Positives = 77/203 (37%), Gaps = 26/203 (12%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPD 439
QC C G G+ C CA GY G C C C G CDP TG C
Sbjct: 984 QCWCQPGVTGKKCDRCAHGYFNFQE-----GGCTACECSHLGNNCDPKTGRCICPPNTIG 1038
Query: 440 IECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADG 499
+C+ C + CK C C S CN C P +GA+C C+ G
Sbjct: 1039 EKCSKCAPNTWGHSITT-GCKACNCSTVGSLDFQCNVNTGQCN-CHPKFSGAKCTECSRG 1096
Query: 500 YFGDPFGEHGPVRPCQPCQC-------NNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQ 552
++ P C C C + +C TG+C C N GI+CD+
Sbjct: 1097 HWNYP--------RCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCT-CKVNVEGIHCDR 1147
Query: 553 CKAGYFGDPLAPNPADKCRACNC 575
C+ G FG A NP C +C C
Sbjct: 1148 CRPGKFGLD-AKNPLG-CSSCYC 1168
Score = 77.8 bits (190), Expect = 5e-14
Identities = 53/184 (28%), Positives = 76/184 (41%), Gaps = 34/184 (18%)
Query: 462 CPCH-NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQ 518
C C+ + +C + P T + C C G C+ C G+ P+ G C+ C
Sbjct: 287 CICYGHARACPLDPATNKSRCE-CEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACN 345
Query: 519 CNNNVDPSA-SGNCDRLT------------GRCLKCIHNTAGIYCDQCKAGYFGDP-LAP 564
C+ + N R G C+ C NTAGI C+ C G+F ++P
Sbjct: 346 CHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSP 405
Query: 565 NPADKCRACNCNPMGSEPVGCRSD----------GTCVCKPGFGGPNCEH------GAFS 608
N C+ C+C+P+GS C D G+C CK GFGG +C+ G
Sbjct: 406 NYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD 465
Query: 609 CPAC 612
C AC
Sbjct: 466 CKAC 469
Score = 75.5 bits (184), Expect = 3e-13
Identities = 66/237 (27%), Positives = 87/237 (36%), Gaps = 50/237 (21%)
Query: 375 PAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGT---CIPCNCQG-GGACDPDT-- 428
PA +C C G C C G+ + R G F T C CNC G C D
Sbjct: 300 PATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENV 359
Query: 429 ----------------GDCYSGDEN-PDIECADCPIGFYN----DPHDPRSCKPCPCHNG 467
G C + +N I C C GF+ P+ PR C+PC C
Sbjct: 360 ARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPI 419
Query: 468 FSCSVMPETEEVVCN--------NCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC 519
S + + +E +C G G C+ CA GY G P C+ C C
Sbjct: 420 GSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYP--------DCKACNC 471
Query: 520 NNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCN 576
+ S N D G C+ C N G C +CK+G+F L + C C C+
Sbjct: 472 SG----LGSKNEDPCFGPCI-CKENVEGGDCSRCKSGFFN--LQEDNWKGCDECFCS 521
Score = 44.3 bits (103), Expect = 7e-04
Identities = 31/117 (26%), Positives = 41/117 (35%), Gaps = 28/117 (23%)
Query: 98 NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCD-CDPAGIAGPC------ 150
N RC C+ G CD+C PGFH T L ++C+ C+ G A C
Sbjct: 303 NKSRCECEHNTCGDSCDQCCPGFHQKPWRAGT---FLTKTECEACNCHGKAEECYYDENV 359
Query: 151 --------------DAGRCV-CKPAVTGERCDRCRSGYYNLDG---GNPEGCTQCFC 189
G C+ C G C+ C G++ G P C C C
Sbjct: 360 ARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHC 416
Score = 35.0 bits (79), Expect = 0.39
Identities = 20/80 (25%), Positives = 31/80 (38%), Gaps = 19/80 (23%)
Query: 9 CLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKC 68
C CF A S + C C+ ++ QC C N +GIHC++C
Sbjct: 1106 CDCFLPGTDATTCDSETKKCSCSDQTGQC-----------------TCKVNVEGIHCDRC 1148
Query: 69 KNGFYRHRERD--RCLPCNC 86
+ G + ++ C C C
Sbjct: 1149 RPGKFGLDAKNPLGCSSCYC 1168
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 301 bits (772), Expect = 2e-81
Identities = 314/1206 (26%), Positives = 465/1206 (38%), Gaps = 210/1206 (17%)
Query: 53 CLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGS---LSARCD-NSGRCSCKPGV 108
CL C T G H C CNC+ G CD +SG+C C+P V
Sbjct: 1509 CLLCQPQTFGCH------------PLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNV 1556
Query: 109 TGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPCD--AGRCVCKPAVTGER 165
TG RCD C PGFH CDC AG A G CD G+C CK V G +
Sbjct: 1557 TGRRCDTCSPGFHGYPRC----------RPCDCHEAGTAPGVCDPLTGQCYCKENVQGPK 1606
Query: 166 CDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAV---- 221
CD+C G ++LD NP+GCT+CFC+G + CRSS+ T D++GW +
Sbjct: 1607 CDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSS------YTRQEFVDMEGWVLLSTDR 1660
Query: 222 -----QRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVD 276
+R L+ RH + + +Y+ AP +LG++ SYG +L ++ +
Sbjct: 1661 QVVPHERQPGTEMLRADLRHVPE-AVPEAFPELYWQAPPSYLGDRVSSYGGTLRYELHSE 1719
Query: 277 --RGGRH---PSAHDVILEGAGLRIT--APLMPLGKTLPCGLTKTYTFRLNEHPSNNWSP 329
RG S DV+L+G + IT P P + G + + N
Sbjct: 1720 TQRGDVFVPMESRPDVVLQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRN--- 1776
Query: 330 QLSYFEYRRLLRNLTALRIRATYGEYSTG-YIDNVTLISARPVS-GAPAPWVEQCICPVG 387
+S E +L +L L+IRA + + S+ ++ V L A P GA A VE C+CP
Sbjct: 1777 TVSREELMMVLASLEQLQIRALFSQISSAVFLRRVALEVASPAGQGALASNVELCLCPAS 1836
Query: 388 YKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPD-IECADC 445
Y+G CQ+CA G+ RD L G C+PC C G C P +G C N + C C
Sbjct: 1837 YRGDSCQECAPGFYRDVKGLF-LGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERC 1895
Query: 446 PIGFYNDPHDPRS-CKPCPC-----HNGFSCSVMPETEEVVCNNCPPGVTGARCELCADG 499
GF + DP + C CPC N F+ + C C PG GA CE CA G
Sbjct: 1896 QAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCL-CKPGYAGASCERCAPG 1954
Query: 500 YFGDPFGEHGPVRPCQPCQCNNNVDPSAS-GNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
+FG+P CQPC C+ N DP+ +CD LTG C C+ +T G C+ C G++
Sbjct: 1955 FFGNPLVLGSS---CQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFY 2011
Query: 559 GDPLAPNPADKCRACNCNPMGSEPV--------------------------------GCR 586
G+ L P C C+C P G+E GCR
Sbjct: 2012 GNALLPG---NCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCR 2068
Query: 587 ---------------SDGTCVCKPGFGGPNC-----------EHGAFSCPA--------- 611
G C C+PG GP C E G C
Sbjct: 2069 PCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQCPGGRCDPHT 2128
Query: 612 --CYNQVKIQMDQFMQQLQRMEALISKAQGGDGV------------VPDTELEGRMQQAE 657
C + ++ Q+ + + G + + D E G +
Sbjct: 2129 GRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHCVVLLLDDLERAGALL--- 2185
Query: 658 QALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVR 717
A+ + LR S A L A + ++ +S L T +++ L Q + +
Sbjct: 2186 PAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQ 2245
Query: 718 DTHRL-------ITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVE 770
D RL Q LA +EA+LG+ + L + L ++
Sbjct: 2246 DARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLAAIRAVDRTLSELMSQTGHLGLANA- 2304
Query: 771 SASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKL-EKTKSLAQQ 829
SA + EQL R + + L +A G + + A Q L+ ++ E+ SL ++
Sbjct: 2305 SAPSGEQLLRTLAEVER--LLWEMRARDLGAPQAAAEAELAAAQRLLARVQEQLSSLWEE 2362
Query: 830 LTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQ-----------VEEAKRIKQK- 877
ATQ DR QH L+D L D + + +EEA + KQ+
Sbjct: 2363 NQALATQTR---DRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEALQRKQEL 2419
Query: 878 -ADSLSSLVTRH-----MDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAK 931
D+ + T H + R +L KEE ++L + R Q + + A
Sbjct: 2420 SRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFSPAG 2479
Query: 932 SRAQEALSMGNATFYEVESILKNLREFDLQVD-----NRKAEAEEAMKRLSYISQKVSDA 986
S+ + + A ++ + NL L V+ R EA A R+ Q DA
Sbjct: 2480 SKLR-LVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDA 2538
Query: 987 SDKT-QQAERALGSAAAD--AQRAKNGAGEALEISSEIEQEIGSLNLEANVTADGALAME 1043
+ + QQA+ + RA+ + + + QE L L +
Sbjct: 2539 AGQALQQADHTWATVVRQGLVDRAQQLLANSTALEEAMLQEQQRLGL-----------VW 2587
Query: 1044 KGLASLKSEMREVEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNAGVTIQDTLNTLD 1103
L ++++R+V + ++ E + M E K AK QDT +
Sbjct: 2588 AALQGARTQLRDVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAAEAQDTATRVQ 2647
Query: 1104 GLLHLM 1109
L M
Sbjct: 2648 SQLQAM 2653
Score = 251 bits (640), Expect = 4e-66
Identities = 192/658 (29%), Positives = 267/658 (40%), Gaps = 140/658 (21%)
Query: 72 FYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDA-GCT 129
FY + R PC C+ G+ C+ G+C C V G C RC G+ + C
Sbjct: 1430 FYNNGAR----PCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCD 1485
Query: 130 QDQRLLD---SKCDCDPAGIAGPC------------------------------------ 150
RL D +C C P I C
Sbjct: 1486 CGARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDT 1545
Query: 151 DAGRCVCKPAVTGERCDRCRSGY------------------------------------- 173
D+G+C C+P VTG RCD C G+
Sbjct: 1546 DSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGP 1605
Query: 174 ---------YNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAV--- 221
++LD NP+GCT+CFC+G + CRSS+ T D++GW +
Sbjct: 1606 KCDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSS------YTRQEFVDMEGWVLLSTD 1659
Query: 222 ------QRNGSPAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFD--- 272
+R L+ RH + + +Y+ AP +LG++ SYG +L ++
Sbjct: 1660 RQVVPHERQPGTEMLRADLRHVPE-AVPEAFPELYWQAPPSYLGDRVSSYGGTLRYELHS 1718
Query: 273 --YRVDRGGRHPSAHDVILEGAGLRIT--APLMPLGKTLPCGLTKTYTFRLNEHPSNNWS 328
R D S DV+L+G + IT P P + G + + N
Sbjct: 1719 ETQRGDVFVPMESRPDVVLQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRN-- 1776
Query: 329 PQLSYFEYRRLLRNLTALRIRATYGEYSTG-YIDNVTLISARPV-SGAPAPWVEQCICPV 386
+S E +L +L L+IRA + + S+ ++ V L A P GA A VE C+CP
Sbjct: 1777 -TVSREELMMVLASLEQLQIRALFSQISSAVFLRRVALEVASPAGQGALASNVELCLCPA 1835
Query: 387 GYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPD-IECAD 444
Y+G CQ+CA G+ RD L G C+PC C G C P +G C N + C
Sbjct: 1836 SYRGDSCQECAPGFYRDVKGLF-LGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCER 1894
Query: 445 CPIGFYNDPHDPRS-CKPCPC-----HNGFSCSVMPETEEVVCNNCPPGVTGARCELCAD 498
C GF + DP + C CPC N F+ + C C PG GA CE CA
Sbjct: 1895 CQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQC-LCKPGYAGASCERCAP 1953
Query: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPS-ASGNCDRLTGRCLKCIHNTAGIYCDQCKAGY 557
G+FG+P CQPC C+ N DP+ +CD LTG C C+ +T G C+ C G+
Sbjct: 1954 GFFGNPLVLGS---SCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGF 2010
Query: 558 FGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGG---PNCEHGAFSCPAC 612
+G+ L P C C+C P G+E S G C+CK G G C+ G F C
Sbjct: 2011 YGNALLPG---NCTRCDCTPCGTEACDPHS-GHCLCKAGVTGRRCDRCQEGHFGFDGC 2064
Score = 125 bits (313), Expect = 3e-28
Identities = 88/273 (32%), Positives = 113/273 (41%), Gaps = 55/273 (20%)
Query: 382 CI-CPVGYKGQFCQDCASG-YKRDSARLGPFGTCIPCNCQGG---GACDPDTGDCYSGDE 436
CI C G C+ C G Y+ + L C CNC+ G C+ TG CY
Sbjct: 393 CIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPN 452
Query: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCH-NGFSCSVMPETEEVVCNN------------ 483
C C GF P SC P P N V+P + V C+
Sbjct: 453 FSGERCDVCAEGFTGFP----SCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRK 508
Query: 484 --------CPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLT 535
C P G CELCA G++G CQPCQC++ A CD T
Sbjct: 509 DPRVGRCLCKPNFQGTHCELCAPGFYGPG---------CQPCQCSS--PGVADDRCDPDT 557
Query: 536 GRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKP 595
G+C +C G CD+C GYF PL C+ C C+P G+ P GC G C+C+P
Sbjct: 558 GQC-RCRVGFEGATCDRCAPGYFHFPL-------CQLCGCSPAGTLPEGCDEAGRCLCQP 609
Query: 596 GFGGPNCE------HGAFSCPACYNQVKIQMDQ 622
F GP+C+ HG +C AC + +DQ
Sbjct: 610 EFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQ 642
Score = 115 bits (287), Expect = 3e-25
Identities = 64/173 (36%), Positives = 88/173 (50%), Gaps = 33/173 (19%)
Query: 26 EVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCN 85
+ C C+ + L + G G C C G C++C GF+ C+PC+
Sbjct: 630 QACTCDPRGA-------LDQLCGAGGLC-RCRPGYTGTACQECSPGFHGFPS---CVPCH 678
Query: 86 CNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLT--DAGCTQDQRLLDSKCDCD 142
C+++GSL A CD SG+CSC+P VTG RCD C+PG + +AG C
Sbjct: 679 CSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAG------------SCH 726
Query: 143 PAGIAGPCDAGR------CVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
PAG+A P D C+C+ V G CDRC+ G++ L NPEGCT+C C
Sbjct: 727 PAGLA-PVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSC 778
Score = 114 bits (286), Expect = 4e-25
Identities = 79/260 (30%), Positives = 106/260 (40%), Gaps = 54/260 (20%)
Query: 381 QCICPVGYKGQFCQDCASGY-------------KRDSARLGPFGTCIPCNCQGGG----A 423
+C C + G+ C CA G+ ++ P G + C+C G A
Sbjct: 446 RCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNA 505
Query: 424 C--DPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVC 481
C DP G C C C GFY C+PC C + + + C
Sbjct: 506 CRKDPRVGRCLCKPNFQGTHCELCAPGFYGP-----GCQPCQCSSPGVADDRCDPDTGQC 560
Query: 482 NNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSAS--GNCDRLTGRCL 539
C G GA C+ CA GYF P CQ C C+ P+ + CD GRCL
Sbjct: 561 R-CRVGFEGATCDRCAPGYFHFPL--------CQLCGCS----PAGTLPEGCDE-AGRCL 606
Query: 540 KCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGG 599
C AG +CD+C+ GY G P C+AC C+P G+ C + G C C+PG+ G
Sbjct: 607 -CQPEFAGPHCDRCRPGYHGFP-------NCQACTCDPRGALDQLCGAGGLCRCRPGYTG 658
Query: 600 PNCE------HGAFSCPACY 613
C+ HG SC C+
Sbjct: 659 TACQECSPGFHGFPSCVPCH 678
Score = 111 bits (277), Expect = 4e-24
Identities = 67/178 (37%), Positives = 82/178 (46%), Gaps = 31/178 (17%)
Query: 15 LLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYR 74
+LPA + + CDC+ Q R+ RCL C N G HCE C GFY
Sbjct: 485 VLPAGQIVN----CDCSAAGTQ----GNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYG 535
Query: 75 HRERDRCLPCNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQR 133
C PC C+S G RCD ++G+C C+ G GA CDRC PG+
Sbjct: 536 ----PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFP--------- 582
Query: 134 LLDSKCDCDPAG-IAGPCD-AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
L C C PAG + CD AGRC+C+P G CDRCR GY+ C C C
Sbjct: 583 -LCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGF-----PNCQACTC 634
Score = 110 bits (276), Expect = 6e-24
Identities = 73/232 (31%), Positives = 94/232 (40%), Gaps = 25/232 (10%)
Query: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG----ACDPDTGDCYSGDEN 437
C C GY G CQ+C+ G+ F +C+PC+C G ACDP +G C
Sbjct: 650 CRCRPGYTGTACQECSPGFHG-------FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRV 702
Query: 438 PDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEV-VCNNCPPGVTGARCELC 496
+ C C G YN P+ C+ CH V P E V C V G C+ C
Sbjct: 703 TGLRCDTCVPGAYNFPY----CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRC 758
Query: 497 ADGYFG-DPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKA 555
G++G P G C C C+ C TG+C C + G C CK
Sbjct: 759 KPGFWGLSPSNPEG----CTRCSCDLRGTLGGVAECQPGTGQCF-CKPHVCGQACASCKD 813
Query: 556 GYFGDPLAPNPADKCRACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCEHGA 606
G+FG L CR+C C+ G+ C G C C+P GP C A
Sbjct: 814 GFFG--LDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPA 863
Score = 105 bits (263), Expect = 2e-22
Identities = 62/200 (31%), Positives = 89/200 (44%), Gaps = 35/200 (17%)
Query: 19 ARATSRREVCDCNGKSRQCIFDRELHRQTGN---------GFRCLNCNDNTDGIHCEKCK 69
A + + + C+C G + C +D E+ R+ + G C++C +T G++CE+C
Sbjct: 350 ANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCL 409
Query: 70 NGFYRHRERDR-----CLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHML- 123
GFYR C CNC S + D +GRC C+P +G RCD C GF
Sbjct: 410 PGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFP 469
Query: 124 ------TDAGCTQDQRLLDSK---CDCDPAGIAGPC-----DAGRCVCKPAVTGERCDRC 169
+ + T++Q L + CDC AG G GRC+CKP G C+ C
Sbjct: 470 SCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELC 529
Query: 170 RSGYYNLDGGNPEGCTQCFC 189
G+Y GC C C
Sbjct: 530 APGFYG------PGCQPCQC 543
Score = 101 bits (251), Expect = 4e-21
Identities = 75/247 (30%), Positives = 98/247 (39%), Gaps = 47/247 (19%)
Query: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCY 432
P V +C+C ++G C+ CA G+ GP C PC C G CDPDTG C
Sbjct: 510 PRVGRCLCKPNFQGTHCELCAPGF------YGP--GCQPCQCSSPGVADDRCDPDTGQCR 561
Query: 433 SGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPE-TEEVVCNNCPPGVTGA 491
C C G+++ P C+ C C +PE +E C P G
Sbjct: 562 CRVGFEGATCDRCAPGYFHFP----LCQLCGCS---PAGTLPEGCDEAGRCLCQPEFAGP 614
Query: 492 RCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRL--TGRCLKCIHNTAGIY 549
C+ C GY G P CQ C C DP G D+L G +C G
Sbjct: 615 HCDRCRPGYHGFP--------NCQACTC----DP--RGALDQLCGAGGLCRCRPGYTGTA 660
Query: 550 CDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCE---HG 605
C +C G+ G P C C+C+ GS C G C C+P G C+ G
Sbjct: 661 CQECSPGFHGFP-------SCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPG 713
Query: 606 AFSCPAC 612
A++ P C
Sbjct: 714 AYNFPYC 720
Score = 97.4 bits (241), Expect = 6e-20
Identities = 70/240 (29%), Positives = 92/240 (38%), Gaps = 51/240 (21%)
Query: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG----ACDPDTGDCY 432
P QC C VG++G C CA GY F C C C G CD + G C
Sbjct: 555 PDTGQCRCRVGFEGATCDRCAPGYFH-------FPLCQLCGCSPAGTLPEGCD-EAGRCL 606
Query: 433 SGDENPDIECADCPIGFYNDPH------DPRSCKPCPCHNGFSCSVMPETEEVVCNNCPP 486
E C C G++ P+ DPR C G C C P
Sbjct: 607 CQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLC------------RCRP 654
Query: 487 GVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTA 546
G TG C+ C+ G+ G P C PC C + + S CD +G+C C
Sbjct: 655 GYTGTACQECSPGFHGFP--------SCVPCHC--SAEGSLHAACDPRSGQC-SCRPRVT 703
Query: 547 GIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVG---CRSDGTCVCKPGFGGPNCE 603
G+ CD C G + P C A +C+P G PV + C+C+ GP+C+
Sbjct: 704 GLRCDTCVPGAYNFPY-------CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCD 756
Score = 72.0 bits (175), Expect = 3e-12
Identities = 48/174 (27%), Positives = 70/174 (40%), Gaps = 23/174 (13%)
Query: 462 CPCH-NGFSCSVMPETE--EVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQP 516
C CH + +C T+ + C C G C+ C G+ P+ CQ
Sbjct: 300 CVCHGHADACDAKDPTDPFRLQCT-CQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
Query: 517 CQCNNNV-----DPS-----ASGNCDRLT---GRCLKCIHNTAGIYCDQCKAGYFGDPLA 563
C C + DP AS + D G C+ C H+T G+ C++C G++ P
Sbjct: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
Query: 564 P-NPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE---HGAFSCPACY 613
P + CR CNC ++ G C C+P F G C+ G P+CY
Sbjct: 419 PLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCY 472
Score = 47.4 bits (111), Expect = 8e-05
Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 46 QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCNSKGSLSARCD-NSGRC 102
Q G G +C C + G C CK+GF+ + D C C C+ G+L C+ +G C
Sbjct: 791 QPGTG-QCF-CKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVC 848
Query: 103 SCKPGVTGARC-----DRCLPGFHML 123
C+P G C D LP H L
Sbjct: 849 RCRPNTQGPTCSEPARDHYLPDLHHL 874
Score = 46.6 bits (109), Expect = 1e-04
Identities = 31/113 (27%), Positives = 43/113 (38%), Gaps = 26/113 (23%)
Query: 101 RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPC---------- 150
+C+C+ G CDRC PGF+ T + C+C G A C
Sbjct: 321 QCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNC--YGHATDCYYDPEVDRRR 378
Query: 151 ----------DAGRCV-CKPAVTGERCDRCRSGYY---NLDGGNPEGCTQCFC 189
G C+ C+ TG C+RC G+Y N +P C +C C
Sbjct: 379 ASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNC 431
Score = 40.0 bits (92), Expect = 0.012
Identities = 26/96 (27%), Positives = 36/96 (37%), Gaps = 19/96 (19%)
Query: 135 LDSKCDCDPAGIAGPCDAG--------RCVCKPAVTGERCDRCRSGYYN-----LDGGNP 181
+ +C C G A CDA +C C+ G CDRC G+ +
Sbjct: 296 IGGRCVCH--GHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSA 353
Query: 182 EGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDG 217
C C CYGH+ C E + + Q +DG
Sbjct: 354 NECQSCNCYGHATDCYYDPEVDRRRAS----QSLDG 385
Score = 36.2 bits (82), Expect = 0.18
Identities = 24/60 (40%), Positives = 26/60 (43%), Gaps = 8/60 (13%)
Query: 377 PWVEQCICPVGYKGQFCQDCASG-YKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDC 431
P QC C GQ C C G + D A FG C C C GGA C+P TG C
Sbjct: 792 PGTGQCFCKPHVCGQACASCKDGFFGLDQADY--FG-CRSCRCDIGGALGQSCEPRTGVC 848
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 245 bits (625), Expect = 2e-64
Identities = 241/925 (26%), Positives = 375/925 (40%), Gaps = 129/925 (13%)
Query: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSA---RCD-NSGRCSCKPGVTGA 111
C T CE C+ + C CNC+ +G++ A CD +SG+C CKP +TG
Sbjct: 1328 CPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGR 1387
Query: 112 RCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPCD--AGRCVCKPAVTGERCDR 168
+CDRC GF+ + C+C+ G G CD G C+CK V G C+
Sbjct: 1388 QCDRCASGFYRFPEC----------VPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNV 1437
Query: 169 CRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPA 228
CR G ++LD N +GCT CFC+G + C SS HK + F D+ GW +
Sbjct: 1438 CREGSFHLDPANLKGCTSCFCFGVNNQCHSS-----HKRRTKF-VDMLGWHLETADRVDI 1491
Query: 229 KLQWSQRHQDVFSSAQRLDPVY----FVAPAKFLGNQQVSYG-----QSLSFDYRVDRGG 279
+ ++ + + Q L +VAP +LG++ SYG Q+ SF D
Sbjct: 1492 PVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVL 1551
Query: 280 RHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRL 339
DV L G + I + + + N +++ +P +S E +
Sbjct: 1552 LEKKP-DVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAP-VSREELMTV 1609
Query: 340 LRNLTALRIRATY-GEYSTGYIDNVTLISARPV-SGAPAPWVEQCICPVGYKGQFCQDCA 397
L L +RI+ Y E + V L A SG A VE C CP Y G CQ C+
Sbjct: 1610 LSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCS 1669
Query: 398 SGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPDIE-CADCPIGFY-NDPH 454
GY RD L G C+PCNC G C +G C + N E C C G+Y N H
Sbjct: 1670 PGYYRDHKGLYT-GRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVH 1728
Query: 455 DPRSCKPCPCH--NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVR 512
SC+ CPC N F+ + +V C+ C G TG +CE CA GYFG+P G
Sbjct: 1729 G--SCRACPCPHTNSFATGCVVNGGDVRCS-CKAGYTGTQCERCAPGYFGNPQKFGG--- 1782
Query: 513 PCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRA 572
CQPC CN+N G+C LTG C+ +P +PA++C
Sbjct: 1783 SCQPCSCNSN---GQLGSCHPLTGDCIN------------------QEPKDSSPAEECDD 1821
Query: 573 C-NCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAF-SCPACYNQVKIQMDQFMQQLQRM 630
C +C + + + K G + G Q K +Q + +
Sbjct: 1822 CDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAI 1881
Query: 631 EALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENS 690
SK +G LE + Q + + AQ++ +++L + +
Sbjct: 1882 SNHGSKIEG---------LERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKE 1932
Query: 691 YQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNI---PASDH 747
++ ++ V + + + + + + L ++ SL E EA L + A+
Sbjct: 1933 LDVKIKNVIRNVHMLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQ 1992
Query: 748 YVGPNGFKSLAQEATRLAESHVESASNMEQ----------------------LTRETEDY 785
NG + A + V+ ++++ + + ++Y
Sbjct: 1993 AKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEY 2052
Query: 786 SKQALSL--VRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTR----------- 832
K A SL R+ L + V S S A LVE+ EK Q+L +
Sbjct: 2053 EKLAASLNEARQELSDKVRELSRS---AGKTSLVEEAEKHARSLQELAKQLEEIKRNASG 2109
Query: 833 -EATQAEIEADRSYQHSLRLL----DSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTR 887
E + ++A +Y++ L + D+ +R S+ + Q + + +KA +LSS +
Sbjct: 2110 DELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDK 2169
Query: 888 HMDEFKRTQKNLGNWKEEAQQLLQN 912
++E K TQK L K+E L N
Sbjct: 2170 LLNEAKMTQKKL---KQEVSPALNN 2191
Score = 120 bits (302), Expect = 5e-27
Identities = 69/201 (34%), Positives = 99/201 (49%), Gaps = 34/201 (16%)
Query: 17 PAARATSRR-EVCDCNGKSRQCIFDRELHRQTGN---------GFRCLNCNDNTDGIHCE 66
PAA S E C+C+G + C +D ++ RQ + G C+NC NT G++CE
Sbjct: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403
Query: 67 KCKNGFYRH-----RERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH 121
+C G+YR D C+PC+C+ + + SGRC CKP G C++C G++
Sbjct: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCE-QGSGRCHCKPNFHGDNCEKCAIGYY 462
Query: 122 ML----------TDAGCTQDQRLLDSK-CDCDPAGIAGP-CDA-GRCVCKPAVTGERCDR 168
++D D K CDC+ G+ CDA GRC+C+P V G RCD
Sbjct: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDT 522
Query: 169 CRSGYYNLDGGNPEGCTQCFC 189
CRSG+Y+ C C+C
Sbjct: 523 CRSGFYSF-----PICQACWC 538
Score = 107 bits (268), Expect = 5e-23
Identities = 56/140 (40%), Positives = 73/140 (52%), Gaps = 14/140 (10%)
Query: 52 RCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTG 110
RCL C +G C+ C++GFY C C C++ GS C + +G+C C+PGVTG
Sbjct: 508 RCL-CRPGVEGPRCDTCRSGFYSF---PICQACWCSALGSYQMPCSSVTGQCECRPGVTG 563
Query: 111 ARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCR 170
RCDRCL G + S CDPAG + G C CK V G C RC+
Sbjct: 564 QRCDRCLSGAYDFPHCQ--------GSSSACDPAGTINS-NLGYCQCKLHVEGPTCSRCK 614
Query: 171 SGYYNLDGGNPEGCTQCFCY 190
Y+NLD NP GC++C C+
Sbjct: 615 LLYWNLDKENPSGCSECKCH 634
Score = 98.6 bits (244), Expect = 3e-20
Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 22/158 (13%)
Query: 22 TSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRC 81
T R C+CNG S QC Q G+G C+NC NT G HCE+C+ G+Y + C
Sbjct: 1681 TGRCVPCNCNGHSNQC--------QDGSGI-CVNCQHNTAGEHCERCQEGYYGNAVHGSC 1731
Query: 82 LPCNCNSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSK 138
C C S + C +G RCSCK G TG +C+RC PG+ G Q
Sbjct: 1732 RACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF-----GNPQKFGGSCQP 1786
Query: 139 CDCDPAGIAGPCD--AGRCV---CKPAVTGERCDRCRS 171
C C+ G G C G C+ K + E CD C S
Sbjct: 1787 CSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 1824
Score = 96.3 bits (238), Expect = 1e-19
Identities = 80/276 (28%), Positives = 108/276 (39%), Gaps = 58/276 (21%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPF---GTCIPCNCQGGGA---CDPDT------ 428
+C C G+ C C +GY + R + C CNC G + DPD
Sbjct: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQAS 377
Query: 429 ----------GDCYSGDEN-PDIECADCPIGFYND---PHD-PRSCKPCPC--HNGFSCS 471
G C + N + C C G+Y P D P C PC C + C
Sbjct: 378 LNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGC- 436
Query: 472 VMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQ-----------CN 520
E C +C P G CE CA GY+ PF P+ P C+
Sbjct: 437 ---EQGSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCD 492
Query: 521 NNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGS 580
N++ CD GRCL C G CD C++G++ P+ C+AC C+ +GS
Sbjct: 493 CNLEGVLPEICD-AHGRCL-CRPGVEGPRCDTCRSGFYSFPI-------CQACWCSALGS 543
Query: 581 EPVGCRS-DGTCVCKPGFGGPNCEH---GAFSCPAC 612
+ C S G C C+PG G C+ GA+ P C
Sbjct: 544 YQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHC 579
Score = 94.0 bits (232), Expect = 7e-19
Identities = 65/217 (29%), Positives = 87/217 (40%), Gaps = 40/217 (18%)
Query: 414 IPCNCQGGGA----CDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFS 469
+PC C GA C P+ G C +C C G Y P CKPC C
Sbjct: 1264 LPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR----CKPCSCGRRL- 1318
Query: 470 CSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN-VDPSAS 528
C M C CPP +CE+C F P+ C+ C C+ +A
Sbjct: 1319 CEEMTGQ----CR-CPPRTVRPQCEVCETHSFS-----FHPMAGCEGCNCSRRGTIEAAM 1368
Query: 529 GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RS 587
CDR +G+C +C G CD+C +G++ P +C CNCN G+EP C
Sbjct: 1369 PECDRDSGQC-RCKPRITGRQCDRCASGFYRFP-------ECVPCNCNRDGTEPGVCDPG 1420
Query: 588 DGTCVCKPGFGGPN---CEHGAF--------SCPACY 613
G C+CK G C G+F C +C+
Sbjct: 1421 TGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCF 1457
Score = 89.0 bits (219), Expect = 2e-17
Identities = 62/197 (31%), Positives = 82/197 (41%), Gaps = 24/197 (12%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
QC C G+ C CA+G+ F C PC+C G C+ TG C
Sbjct: 1284 QCPCQPNVIGRQCTRCATGHY-------GFPRCKPCSC-GRRLCEEMTGQCRCPPRTVRP 1335
Query: 441 ECADCPIGFYNDPHDPRSCKPCPC-HNGFSCSVMPETEEVVCN-NCPPGVTGARCELCAD 498
+C C ++ H C+ C C G + MPE + C P +TG +C+ CA
Sbjct: 1336 QCEVCETHSFSF-HPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCAS 1394
Query: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
G++ P C PC CN D + G CD TG CL C N G C+ C+ G F
Sbjct: 1395 GFYRFP--------ECVPCNCNR--DGTEPGVCDPGTGACL-CKENVEGTECNVCREGSF 1443
Query: 559 GDPLAPNPADKCRACNC 575
L P C +C C
Sbjct: 1444 --HLDPANLKGCTSCFC 1458
Score = 87.4 bits (215), Expect = 7e-17
Identities = 74/259 (28%), Positives = 99/259 (38%), Gaps = 76/259 (29%)
Query: 382 CI-CPVGYKGQFCQDCASGYKRDSARLGPFGT-------CIPCNC--QGGGACDPDTGDC 431
CI C G C+ CA GY R P+G CIPC+C + C+ +G C
Sbjct: 390 CINCQHNTAGVNCEQCAKGYYR------PYGVPVDAPDGCIPCSCDPEHADGCEQGSGRC 443
Query: 432 YSGDENPDIECADCPIGFYNDP---------------HDP--RSCKPCPCHNGFSCSVMP 474
+ C C IG+YN P DP K C C+ V+P
Sbjct: 444 HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLE---GVLP 500
Query: 475 ETEEVVCNN-----CPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASG 529
E +C+ C PGV G RC+ C G++ P CQ C C SA G
Sbjct: 501 E----ICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI--------CQACWC------SALG 542
Query: 530 N----CDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC 585
+ C +TG+C +C G CD+C +G + P + C +P G
Sbjct: 543 SYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDFPHCQGSSSAC----------DPAGT 591
Query: 586 RSD--GTCVCKPGFGGPNC 602
+ G C CK GP C
Sbjct: 592 INSNLGYCQCKLHVEGPTC 610
Score = 75.1 bits (183), Expect = 3e-13
Identities = 52/171 (30%), Positives = 73/171 (42%), Gaps = 22/171 (12%)
Query: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQC 519
C C+ + E++ C G C+ C GY + C+ C C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
Query: 520 NNNV-----DP-----SASGNCDRL---TGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
+ + DP AS N + G C+ C HNTAG+ C+QC GY+ P
Sbjct: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
Query: 567 A-DKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
A D C C+C+P ++ GC + G C CKP F G NCE G ++ P C
Sbjct: 419 APDGCIPCSCDPEHAD--GCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFC 467
Score = 74.3 bits (181), Expect = 6e-13
Identities = 70/246 (28%), Positives = 92/246 (37%), Gaps = 46/246 (18%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDS--ARLGPFGTCIP------------CNCQGGGACDP 426
+C C + G C+ CA GY R+ F P C+C G P
Sbjct: 442 RCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVL-P 500
Query: 427 DTGD------CYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV 480
+ D C G E P C C GFY+ P C+ C C + MP +
Sbjct: 501 EICDAHGRCLCRPGVEGP--RCDTCRSGFYSFP----ICQACWC-SALGSYQMPCSSVTG 553
Query: 481 CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK 540
C PGVTG RC+ C G + P + G C P +G + G C +
Sbjct: 554 QCECRPGVTGQRCDRCLSGAYDFPHCQ-GSSSACDP-----------AGTINSNLGYC-Q 600
Query: 541 CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG--SEPVGCR-SDGTCVCKPGF 597
C + G C +CK Y+ L C C C+ G S CR DG C CK
Sbjct: 601 CKLHVEGPTCSRCKLLYWN--LDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHV 658
Query: 598 GGPNCE 603
GG +C+
Sbjct: 659 GGDSCD 664
Score = 73.6 bits (179), Expect = 1e-12
Identities = 52/177 (29%), Positives = 73/177 (41%), Gaps = 41/177 (23%)
Query: 447 IGFYNDPHDPRSCKPCPCH----NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFG 502
+ FY+ + PC CH G CS PE + C P V G +C CA G++G
Sbjct: 1256 VAFYH-----KGALPCECHPTGATGPHCS--PEGGQCPCQ---PNVIGRQCTRCATGHYG 1305
Query: 503 DPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPL 562
P C+PC C + C+ +TG+C +C T C+ C+ F
Sbjct: 1306 FP--------RCKPCSCGRRL-------CEEMTGQC-RCPPRTVRPQCEVCETHSF---- 1345
Query: 563 APNPADKCRACNCNPMG----SEPVGCRSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
+ +P C CNC+ G + P R G C CKP G C+ G + P C
Sbjct: 1346 SFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPEC 1402
Score = 67.4 bits (163), Expect = 7e-11
Identities = 50/180 (27%), Positives = 71/180 (39%), Gaps = 13/180 (7%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
QC C G GQ C C SG G C P G + + G C
Sbjct: 554 QCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPA-----GTINSNLGYCQCKLHVEGP 608
Query: 441 ECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVMPETEEVVCN-NCPPGVTGARCELCAD 498
C+ C + ++N D +P C C CH + S E + + +C V G C+ C D
Sbjct: 609 TCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCED 668
Query: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
GYF E CQ CQC ++ + S C +G C +C + G C + + Y+
Sbjct: 669 GYFA---LEKSNYFGCQGCQC--DIGGALSSMCSGPSGVC-QCREHVVGKVCQRPENNYY 722
Score = 58.2 bits (139), Expect = 4e-08
Identities = 42/156 (26%), Positives = 63/156 (40%), Gaps = 23/156 (14%)
Query: 30 CNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCN 87
C G S C ++ G C + +G C +CK ++ + + C C C+
Sbjct: 579 CQGSSSACDPAGTINSNLGY----CQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCH 634
Query: 88 SKGSLSARCD---NSGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDC 141
G++S + G C CK V G CD C G+ L + GC C C
Sbjct: 635 KAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGC--------QGCQC 686
Query: 142 DPAG-IAGPCD--AGRCVCKPAVTGERCDRCRSGYY 174
D G ++ C +G C C+ V G+ C R + YY
Sbjct: 687 DIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
Score = 53.1 bits (126), Expect = 1e-06
Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Query: 139 CDCDPAGIAGP-C--DAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSAS 195
C+C P G GP C + G+C C+P V G +C RC +G+Y P C + C +
Sbjct: 1266 CECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQ 1325
Query: 196 CR 197
CR
Sbjct: 1326 CR 1327
Score = 45.8 bits (107), Expect = 2e-04
Identities = 34/130 (26%), Positives = 45/130 (34%), Gaps = 33/130 (25%)
Query: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDP 143
CN N+ L RC C+ G CDRC G++ +Q C+C
Sbjct: 308 CNINNPEKLF-------RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCH- 359
Query: 144 AGIAGPC--------------------DAGRCV-CKPAVTGERCDRCRSGYYNLDG---G 179
G A C G C+ C+ G C++C GYY G
Sbjct: 360 -GHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
Query: 180 NPEGCTQCFC 189
P+GC C C
Sbjct: 419 APDGCIPCSC 428
Score = 40.8 bits (94), Expect = 0.007
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 11/72 (15%)
Query: 135 LDSKCDC----DPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEG------C 184
+ +C C + I P RC C+ GE CDRC +G YN P C
Sbjct: 295 IGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTG-YNQRRWRPAAWEQSHEC 353
Query: 185 TQCFCYGHSASC 196
C C+GH+++C
Sbjct: 354 EACNCHGHASNC 365
Score = 37.7 bits (86), Expect = 0.061
Identities = 49/256 (19%), Positives = 103/256 (40%), Gaps = 40/256 (15%)
Query: 856 SRLQGVSDQSFQVEEAKRIKQKADSLS-------SLVTRHMDEFKRTQKNLGNWKEEAQQ 908
S+LQG+S + +E+ + ++ +A L S ++ H + + ++ L + +E +
Sbjct: 1845 SQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFET 1904
Query: 909 LLQNGKSGREKSDQLLSRANLAKSRAQEA----------LSMGNA--TFYEVE------- 949
L + + K+ L + N A A+E + M N T+ +
Sbjct: 1905 LQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHMLNRIRTWQKTHQGENNGL 1964
Query: 950 --SILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRA 1007
SI +L E++ ++ + +A +EA + + A+ Q+ ERALG+ +
Sbjct: 1965 ANSIRDSLNEYEAKLSDLRARLQEA-------AAQAKQANGLNQENERALGAIQRQVKEI 2017
Query: 1008 KNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEF 1067
+ + + + + + L+ N+ +K L + + E EL K E
Sbjct: 2018 NSLQSDFTKYLTTADSSL----LQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVREL 2073
Query: 1068 DTNMDAVQMVITEAQK 1083
+ +V EA+K
Sbjct: 2074 SRSAGKTSLV-EEAEK 2088
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 235 bits (600), Expect = 2e-61
Identities = 274/1077 (25%), Positives = 442/1077 (41%), Gaps = 165/1077 (15%)
Query: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSA---RCD-NSGRCSCKPGVTGA 111
C T CE C+ + C CNC+ +G++ A CD +SG+C CKP +TG
Sbjct: 1328 CPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGR 1387
Query: 112 RCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPCD--AGRCVCKPAVTGERCDR 168
+CDRC GF+ + C+C+ G G CD G C+CK V G C+
Sbjct: 1388 QCDRCASGFYRFPEC----------VPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNV 1437
Query: 169 CRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPA 228
CR G ++LD N +GCT CFC+G + C SS HK + F D+ GW +
Sbjct: 1438 CREGSFHLDPANLKGCTSCFCFGVNNQCHSS-----HKRRTKF-VDMLGWHLETADRVDI 1491
Query: 229 KLQWSQRHQDVFSSAQRLDPVY----FVAPAKFLGNQQVSYG-----QSLSFDYRVDRGG 279
+ ++ + + Q L +VAP +LG++ SYG Q+ SF D
Sbjct: 1492 PVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVL 1551
Query: 280 RHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRL 339
DV L G + I + + + N +++ +P +S E +
Sbjct: 1552 LEKKP-DVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAP-VSREELMTV 1609
Query: 340 LRNLTALRIRATY-GEYSTGYIDNVTLISARPV-SGAPAPWVEQCICPVGYKGQFCQDCA 397
L L +RI+ Y E + V L A SG A VE C CP Y G CQ C+
Sbjct: 1610 LSRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCS 1669
Query: 398 SGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPDIE-CADCPIGFY-NDPH 454
GY RD L G C+PCNC G C +G C + N E C C G+Y N H
Sbjct: 1670 PGYYRDHKGLYT-GRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVH 1728
Query: 455 DPRSCKPCPCH--NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVR 512
SC+ CPC N F+ + +V C+ C G TG +CE CA GYFG+P G
Sbjct: 1729 G--SCRACPCPHTNSFATGCVVNGGDVRCS-CKAGYTGTQCERCAPGYFGNPQKFGG--- 1782
Query: 513 PCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRA 572
CQPC CN+N G+C LTG C+ +P +PA++C
Sbjct: 1783 SCQPCSCNSN---GQLGSCHPLTGDCIN------------------QEPKDSSPAEECDD 1821
Query: 573 C-NCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAF-SCPACYNQVKIQMDQFMQQLQRM 630
C +C + + + K G + G Q K +Q + +
Sbjct: 1822 CDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAI 1881
Query: 631 EALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENS 690
SK +G LE + Q + + AQ++ +++L
Sbjct: 1882 SNHGSKIEG---------LERELTDLNQEFETLQEKAQVNSRKAQTLN------------ 1920
Query: 691 YQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVG 750
+++ + + L + +N +R+ H L+ Q+ + E GN N+P+ D
Sbjct: 1921 -----NNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGE-----GN-NVPSGD---- 1965
Query: 751 PNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRK-----ALHEGVGSGS 805
F EA R+ N + RE E +++ L+ + H+G +G
Sbjct: 1966 ---FSREWAEAQRMMRE--LRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGL 2020
Query: 806 GSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQS 865
+ ++ L E K L +L A QA+ +A+ Q + R L ++ R Q S
Sbjct: 2021 AN---SIRDSLNEYEAKLSDLRARLQEAAAQAK-QANGLNQENERALGAIQR-QVKEINS 2075
Query: 866 FQVEEAKRIKQKADSL--SSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQL 923
Q + K + SL +++ + M++ ++ + L EA+Q E SD++
Sbjct: 2076 LQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQ---------ELSDKV 2126
Query: 924 LSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVD--NRKAEAEEAMKRLSYISQ 981
L++S + +L E E ++L+E Q++ R A +E ++
Sbjct: 2127 ---RELSRSAGKTSL------VEEAEKHARSLQELAKQLEEIKRNASGDELVR------- 2170
Query: 982 KVSDASDKTQQAERALGSAAADAQRAKNGAGEALE--ISSEIEQEIGSLNLEANVTADGA 1039
DA+ + A+ +A A RA + + AL+ I ++ ++ +L+ ++ + A
Sbjct: 2171 CAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEA 2230
Query: 1040 LAMEKGLASLKSEMREVEGELE--------RKELEFDTNMDAVQMVITEAQKVDTRA 1088
+K LK E+ L+ +KE+ DTN+ ++ + Q+ D A
Sbjct: 2231 KMTQK---KLKQEVSPALNNLQQTLNIVTVQKEV-IDTNLTTLRDGLHGIQRGDIDA 2283
Score = 120 bits (302), Expect = 5e-27
Identities = 69/201 (34%), Positives = 99/201 (49%), Gaps = 34/201 (16%)
Query: 17 PAARATSRR-EVCDCNGKSRQCIFDRELHRQTGN---------GFRCLNCNDNTDGIHCE 66
PAA S E C+C+G + C +D ++ RQ + G C+NC NT G++CE
Sbjct: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403
Query: 67 KCKNGFYRH-----RERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH 121
+C G+YR D C+PC+C+ + + SGRC CKP G C++C G++
Sbjct: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCE-QGSGRCHCKPNFHGDNCEKCAIGYY 462
Query: 122 ML----------TDAGCTQDQRLLDSK-CDCDPAGIAGP-CDA-GRCVCKPAVTGERCDR 168
++D D K CDC+ G+ CDA GRC+C+P V G RCD
Sbjct: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDT 522
Query: 169 CRSGYYNLDGGNPEGCTQCFC 189
CRSG+Y+ C C+C
Sbjct: 523 CRSGFYSF-----PICQACWC 538
Score = 107 bits (268), Expect = 5e-23
Identities = 56/140 (40%), Positives = 73/140 (52%), Gaps = 14/140 (10%)
Query: 52 RCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTG 110
RCL C +G C+ C++GFY C C C++ GS C + +G+C C+PGVTG
Sbjct: 508 RCL-CRPGVEGPRCDTCRSGFYSF---PICQACWCSALGSYQMPCSSVTGQCECRPGVTG 563
Query: 111 ARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCR 170
RCDRCL G + S CDPAG + G C CK V G C RC+
Sbjct: 564 QRCDRCLSGAYDFPHCQ--------GSSSACDPAGTINS-NLGYCQCKLHVEGPTCSRCK 614
Query: 171 SGYYNLDGGNPEGCTQCFCY 190
Y+NLD NP GC++C C+
Sbjct: 615 LLYWNLDKENPSGCSECKCH 634
Score = 98.6 bits (244), Expect = 3e-20
Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 22/158 (13%)
Query: 22 TSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRC 81
T R C+CNG S QC Q G+G C+NC NT G HCE+C+ G+Y + C
Sbjct: 1681 TGRCVPCNCNGHSNQC--------QDGSGI-CVNCQHNTAGEHCERCQEGYYGNAVHGSC 1731
Query: 82 LPCNCNSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSK 138
C C S + C +G RCSCK G TG +C+RC PG+ G Q
Sbjct: 1732 RACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF-----GNPQKFGGSCQP 1786
Query: 139 CDCDPAGIAGPCD--AGRCV---CKPAVTGERCDRCRS 171
C C+ G G C G C+ K + E CD C S
Sbjct: 1787 CSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 1824
Score = 96.3 bits (238), Expect = 1e-19
Identities = 80/276 (28%), Positives = 108/276 (39%), Gaps = 58/276 (21%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPF---GTCIPCNCQGGGA---CDPDT------ 428
+C C G+ C C +GY + R + C CNC G + DPD
Sbjct: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQAS 377
Query: 429 ----------GDCYSGDEN-PDIECADCPIGFYND---PHD-PRSCKPCPC--HNGFSCS 471
G C + N + C C G+Y P D P C PC C + C
Sbjct: 378 LNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGC- 436
Query: 472 VMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQ-----------CN 520
E C +C P G CE CA GY+ PF P+ P C+
Sbjct: 437 ---EQGSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCD 492
Query: 521 NNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGS 580
N++ CD GRCL C G CD C++G++ P+ C+AC C+ +GS
Sbjct: 493 CNLEGVLPEICD-AHGRCL-CRPGVEGPRCDTCRSGFYSFPI-------CQACWCSALGS 543
Query: 581 EPVGCRS-DGTCVCKPGFGGPNCEH---GAFSCPAC 612
+ C S G C C+PG G C+ GA+ P C
Sbjct: 544 YQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHC 579
Score = 94.0 bits (232), Expect = 7e-19
Identities = 65/217 (29%), Positives = 87/217 (40%), Gaps = 40/217 (18%)
Query: 414 IPCNCQGGGA----CDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFS 469
+PC C GA C P+ G C +C C G Y P CKPC C
Sbjct: 1264 LPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR----CKPCSCGRRL- 1318
Query: 470 CSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN-VDPSAS 528
C M C CPP +CE+C F P+ C+ C C+ +A
Sbjct: 1319 CEEMTGQ----CR-CPPRTVRPQCEVCETHSFS-----FHPMAGCEGCNCSRRGTIEAAM 1368
Query: 529 GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RS 587
CDR +G+C +C G CD+C +G++ P +C CNCN G+EP C
Sbjct: 1369 PECDRDSGQC-RCKPRITGRQCDRCASGFYRFP-------ECVPCNCNRDGTEPGVCDPG 1420
Query: 588 DGTCVCKPGFGGPN---CEHGAF--------SCPACY 613
G C+CK G C G+F C +C+
Sbjct: 1421 TGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCF 1457
Score = 89.0 bits (219), Expect = 2e-17
Identities = 62/197 (31%), Positives = 82/197 (41%), Gaps = 24/197 (12%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
QC C G+ C CA+G+ F C PC+C G C+ TG C
Sbjct: 1284 QCPCQPNVIGRQCTRCATGHY-------GFPRCKPCSC-GRRLCEEMTGQCRCPPRTVRP 1335
Query: 441 ECADCPIGFYNDPHDPRSCKPCPC-HNGFSCSVMPETEEVVCN-NCPPGVTGARCELCAD 498
+C C ++ H C+ C C G + MPE + C P +TG +C+ CA
Sbjct: 1336 QCEVCETHSFSF-HPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCAS 1394
Query: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
G++ P C PC CN D + G CD TG CL C N G C+ C+ G F
Sbjct: 1395 GFYRFP--------ECVPCNCNR--DGTEPGVCDPGTGACL-CKENVEGTECNVCREGSF 1443
Query: 559 GDPLAPNPADKCRACNC 575
L P C +C C
Sbjct: 1444 --HLDPANLKGCTSCFC 1458
Score = 87.4 bits (215), Expect = 7e-17
Identities = 74/259 (28%), Positives = 99/259 (38%), Gaps = 76/259 (29%)
Query: 382 CI-CPVGYKGQFCQDCASGYKRDSARLGPFGT-------CIPCNC--QGGGACDPDTGDC 431
CI C G C+ CA GY R P+G CIPC+C + C+ +G C
Sbjct: 390 CINCQHNTAGVNCEQCAKGYYR------PYGVPVDAPDGCIPCSCDPEHADGCEQGSGRC 443
Query: 432 YSGDENPDIECADCPIGFYNDP---------------HDP--RSCKPCPCHNGFSCSVMP 474
+ C C IG+YN P DP K C C+ V+P
Sbjct: 444 HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLE---GVLP 500
Query: 475 ETEEVVCNN-----CPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASG 529
E +C+ C PGV G RC+ C G++ P CQ C C SA G
Sbjct: 501 E----ICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI--------CQACWC------SALG 542
Query: 530 N----CDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC 585
+ C +TG+C +C G CD+C +G + P + C +P G
Sbjct: 543 SYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDFPHCQGSSSAC----------DPAGT 591
Query: 586 RSD--GTCVCKPGFGGPNC 602
+ G C CK GP C
Sbjct: 592 INSNLGYCQCKLHVEGPTC 610
Score = 75.1 bits (183), Expect = 3e-13
Identities = 52/171 (30%), Positives = 73/171 (42%), Gaps = 22/171 (12%)
Query: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQC 519
C C+ + E++ C G C+ C GY + C+ C C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
Query: 520 NNNV-----DP-----SASGNCDRL---TGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
+ + DP AS N + G C+ C HNTAG+ C+QC GY+ P
Sbjct: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
Query: 567 A-DKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
A D C C+C+P ++ GC + G C CKP F G NCE G ++ P C
Sbjct: 419 APDGCIPCSCDPEHAD--GCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFC 467
Score = 74.3 bits (181), Expect = 6e-13
Identities = 70/246 (28%), Positives = 92/246 (37%), Gaps = 46/246 (18%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDS--ARLGPFGTCIP------------CNCQGGGACDP 426
+C C + G C+ CA GY R+ F P C+C G P
Sbjct: 442 RCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVL-P 500
Query: 427 DTGD------CYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV 480
+ D C G E P C C GFY+ P C+ C C + MP +
Sbjct: 501 EICDAHGRCLCRPGVEGP--RCDTCRSGFYSFP----ICQACWC-SALGSYQMPCSSVTG 553
Query: 481 CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLK 540
C PGVTG RC+ C G + P + G C P +G + G C +
Sbjct: 554 QCECRPGVTGQRCDRCLSGAYDFPHCQ-GSSSACDP-----------AGTINSNLGYC-Q 600
Query: 541 CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG--SEPVGCR-SDGTCVCKPGF 597
C + G C +CK Y+ L C C C+ G S CR DG C CK
Sbjct: 601 CKLHVEGPTCSRCKLLYWN--LDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHV 658
Query: 598 GGPNCE 603
GG +C+
Sbjct: 659 GGDSCD 664
Score = 73.6 bits (179), Expect = 1e-12
Identities = 52/177 (29%), Positives = 73/177 (41%), Gaps = 41/177 (23%)
Query: 447 IGFYNDPHDPRSCKPCPCH----NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFG 502
+ FY+ + PC CH G CS PE + C P V G +C CA G++G
Sbjct: 1256 VAFYH-----KGALPCECHPTGATGPHCS--PEGGQCPCQ---PNVIGRQCTRCATGHYG 1305
Query: 503 DPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPL 562
P C+PC C + C+ +TG+C +C T C+ C+ F
Sbjct: 1306 FP--------RCKPCSCGRRL-------CEEMTGQC-RCPPRTVRPQCEVCETHSF---- 1345
Query: 563 APNPADKCRACNCNPMG----SEPVGCRSDGTCVCKPGFGGPNCEH---GAFSCPAC 612
+ +P C CNC+ G + P R G C CKP G C+ G + P C
Sbjct: 1346 SFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPEC 1402
Score = 67.4 bits (163), Expect = 7e-11
Identities = 50/180 (27%), Positives = 71/180 (39%), Gaps = 13/180 (7%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
QC C G GQ C C SG G C P G + + G C
Sbjct: 554 QCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPA-----GTINSNLGYCQCKLHVEGP 608
Query: 441 ECADCPIGFYN-DPHDPRSCKPCPCHNGFSCSVMPETEEVVCN-NCPPGVTGARCELCAD 498
C+ C + ++N D +P C C CH + S E + + +C V G C+ C D
Sbjct: 609 TCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCED 668
Query: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
GYF E CQ CQC ++ + S C +G C +C + G C + + Y+
Sbjct: 669 GYFA---LEKSNYFGCQGCQC--DIGGALSSMCSGPSGVC-QCREHVVGKVCQRPENNYY 722
Score = 58.2 bits (139), Expect = 4e-08
Identities = 42/156 (26%), Positives = 63/156 (40%), Gaps = 23/156 (14%)
Query: 30 CNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCN 87
C G S C ++ G C + +G C +CK ++ + + C C C+
Sbjct: 579 CQGSSSACDPAGTINSNLGY----CQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCH 634
Query: 88 SKGSLSARCD---NSGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDC 141
G++S + G C CK V G CD C G+ L + GC C C
Sbjct: 635 KAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGC--------QGCQC 686
Query: 142 DPAG-IAGPCD--AGRCVCKPAVTGERCDRCRSGYY 174
D G ++ C +G C C+ V G+ C R + YY
Sbjct: 687 DIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
Score = 53.1 bits (126), Expect = 1e-06
Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Query: 139 CDCDPAGIAGP-C--DAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSAS 195
C+C P G GP C + G+C C+P V G +C RC +G+Y P C + C +
Sbjct: 1266 CECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQ 1325
Query: 196 CR 197
CR
Sbjct: 1326 CR 1327
Score = 45.8 bits (107), Expect = 2e-04
Identities = 34/130 (26%), Positives = 45/130 (34%), Gaps = 33/130 (25%)
Query: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDP 143
CN N+ L RC C+ G CDRC G++ +Q C+C
Sbjct: 308 CNINNPEKLF-------RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCH- 359
Query: 144 AGIAGPC--------------------DAGRCV-CKPAVTGERCDRCRSGYYNLDG---G 179
G A C G C+ C+ G C++C GYY G
Sbjct: 360 -GHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
Query: 180 NPEGCTQCFC 189
P+GC C C
Sbjct: 419 APDGCIPCSC 428
Score = 40.8 bits (94), Expect = 0.007
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 11/72 (15%)
Query: 135 LDSKCDC----DPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEG------C 184
+ +C C + I P RC C+ GE CDRC +G YN P C
Sbjct: 295 IGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTG-YNQRRWRPAAWEQSHEC 353
Query: 185 TQCFCYGHSASC 196
C C+GH+++C
Sbjct: 354 EACNCHGHASNC 365
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 225 bits (573), Expect = 2e-58
Identities = 174/599 (29%), Positives = 254/599 (42%), Gaps = 86/599 (14%)
Query: 28 CDCNGKSRQC--IFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRER---DRCL 82
C+CNG + C ++ CLNC NT+G C KCK GF+ + C
Sbjct: 764 CNCNGHASSCDPVYGH-----------CLNCQHNTEGPQCNKCKAGFFGDAMKATATSCR 812
Query: 83 PCNC---NSKGSLSARC----DNSGRC-SCKPGVTGARCDRCLPGFHMLTDAGCTQDQRL 134
PC C ++ S C D C +C PG TG RC+ C PG+ + + +
Sbjct: 813 PCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPV 872
Query: 135 LDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSA 194
CD G G C CK V G C+ C G ++L NP+GC +CFC G S
Sbjct: 873 NQEIVRCDERGSMGTSGEA-CRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCMGVSR 931
Query: 195 SCRSSA--------------EYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVF 240
C SS+ +S+ ST H +G + +P +L +S H+ +
Sbjct: 932 HCTSSSWSRAQLHGASEEPGHFSLTNAAST-HTTNEGIFSP----TPGELGFSSFHRLLS 986
Query: 241 SSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHD---VILEGAGLRIT 297
P ++ P++FLG++ SYG L F H V+L+G + +
Sbjct: 987 G------PYFWSLPSRFLGDKVTSYGGELRFTVTQRSQPGSTPLHGQPLVVLQGNNIILE 1040
Query: 298 APLMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRL-LRNLTALRIRATYGEY- 355
+ + G T+ E Q + E+ + L + L IRA+Y +
Sbjct: 1041 HHV---AQEPSPGQPSTFIVPFREQAWQRPDGQPATREHLLMALAGIDTLLIRASYAQQP 1097
Query: 356 STGYIDNVTLISARPVSGA--PAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTC 413
+ + +++ A P PA VEQC CP GY+G CQDC +GY R + L GTC
Sbjct: 1098 AESRVSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGL-YLGTC 1156
Query: 414 IPCNCQG-GGACDPDTGDCYSGDENPD-IECADCPIGFYNDPH--DPRSCKPCPCHNGFS 469
C+C G AC+P+TG C + + C C G+Y D P+ C+ CPC+ +
Sbjct: 1157 ERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPA 1216
Query: 470 CSVMPET------EEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQ-------P 516
T C+ C PG +G CE CA GY+G+P +PCQ P
Sbjct: 1217 AGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNP----SQGQPCQRDSQVPGP 1272
Query: 517 CQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNC 575
CN + S S CD G+C +C G+ C C+ +F L+ + D C C C
Sbjct: 1273 IGCNCDPQGSVSSQCD-AAGQC-QCKAQVEGLTCSHCRPHHF--HLSASNPDGCLPCFC 1327
Score = 206 bits (524), Expect = 1e-52
Identities = 170/529 (32%), Positives = 233/529 (44%), Gaps = 56/529 (10%)
Query: 26 EVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR---CL 82
E C C+G S C +TG C C +T+G CE+C+ G+Y +R C
Sbjct: 1157 ERCSCHGHSEAC------EPETG---ACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQ 1207
Query: 83 PCNCN---SKGSLSARC----DNSGRC-SCKPGVTGARCDRCLPGFHMLTDAG--CTQDQ 132
C C + G + C D C +C PG +G C+RC PG++ G C +D
Sbjct: 1208 LCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDS 1267
Query: 133 RLLDS-KCDCDPAG-IAGPCDA-GRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
++ C+CDP G ++ CDA G+C CK V G C CR +++L NP+GC CFC
Sbjct: 1268 QVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327
Query: 190 YGHSASCRSSAEYSVHKITSTFHQ-DVDGWKAV--QRN----GSPAKLQWSQRHQDVFSS 242
G + C SSA Y+ H I++ F D G+ V QRN G + Q F +
Sbjct: 1328 MGITQQCASSA-YTRHLISTHFAPGDFQGFALVNPQRNSRLTGEFTVEPVPEGAQLSFGN 1386
Query: 243 AQRL--DPVYFVAPAKFLGNQQVSYGQSLSF--DYRVDRGGRHPSAHDVILEGAGLRITA 298
+L + Y+ P + G++ +YG L + Y G S DV + G + + A
Sbjct: 1387 FAQLGHESFYWQLPETYQGDKVAAYGGKLRYTLSYTAGPQGSPLSDPDVQITGNNIMLVA 1446
Query: 299 PLMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRL-LRNLTALRIRATYGEYS- 356
L ++Y E Q + E+ + L +L L IRAT+
Sbjct: 1447 S----QPALQGPERRSYEIMFREEFWRRPDGQPATREHLLMALADLDELLIRATFSSVPL 1502
Query: 357 TGYIDNVTLISARP-VSGAP-APWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCI 414
I V+L A+P S P A VE+C CP GY G CQDCA GY R + L G C
Sbjct: 1503 AASISAVSLEVAQPGPSNRPRALEVEECRCPPGYIGLSCQDCAPGYTRTGSGL-YLGHCE 1561
Query: 415 PCNCQG-GGACDPDTGDCYSGDENPDIE-CADCPIGFYND--PHDPRSCKPCPCHNGFSC 470
C C G C P+TG C N E C C G+Y D P C+PC C
Sbjct: 1562 LCECNGHSDLCHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPE 1621
Query: 471 SVMPETEEVV------CNNCPPGVTGARCELCADGYFGDPFGEHGPVRP 513
++ T E + C C PG TG CE C GY G+P + G P
Sbjct: 1622 NMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLP 1670
Score = 159 bits (401), Expect = 2e-38
Identities = 133/441 (30%), Positives = 195/441 (44%), Gaps = 53/441 (12%)
Query: 169 CRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQ-----R 223
C G++ L+ + C CFC+G ++ C+S+ + +I F Q D +K V +
Sbjct: 505 CPDGHFYLE--HSAACLPCFCFGITSVCQSTRRFR-DQIRLRFDQP-DDFKGVNVTMPAQ 560
Query: 224 NGSPAKLQWSQRHQDVFSSAQRLD--------PVYFVAPAKFLGNQQVSYGQSLSFD--Y 273
G+P + Q +D ++ P +FLGN+ SYG SL ++ Y
Sbjct: 561 PGTPPLSSTQLQIDPSLHEFQLVDLSRRFLVHDSFWALPEQFLGNKVDSYGGSLRYNVRY 620
Query: 274 RVDRGGRHPSAH-DVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLS 332
+ RG P DV+L GAG R+ + T P L + EH + +
Sbjct: 621 ELARGMLEPVQRPDVVLMGAGYRLLS--RGHTPTQPGALNQRQVQFSEEHWVHESGRPVQ 678
Query: 333 YFEYRRLLRNLTALRIRATYGEY--STGYID---NVTLISARPVSGAPAPWVEQCICPVG 387
E ++L++L A+ I+ Y S G D + T+ A S A VE+C CP+G
Sbjct: 679 RAELLQVLQSLEAVLIQTVYNTKMASVGLSDIAMDTTVTHA--TSHGRAHSVEECRCPIG 736
Query: 388 YKGQFCQDCASGYKRDSARLGPF-GTCIPCNCQG-GGACDPDTGDCYSGDENPD-IECAD 444
Y G C+ C + + R GP+ GTC CNC G +CDP G C + N + +C
Sbjct: 737 YSGLSCESCDAHFTRVPG--GPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGPQCNK 794
Query: 445 CPIGFYNDPHDPR--SCKPCPC-----HNGFSCSVMPETE-EVVCNNCPPGVTGARCELC 496
C GF+ D SC+PCPC FS + +T+ + C+ C PG TG RCE C
Sbjct: 795 CKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESC 854
Query: 497 ADGYFGDPFGEHGPVRPC--QPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCK 554
A GY G+P G RP + +C+ SG R C +N G C++C
Sbjct: 855 APGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACR-------CKNNVVGRLCNECA 907
Query: 555 AGYFGDPLAPNPADKCRACNC 575
G F L+ D C C C
Sbjct: 908 DGSF--HLSTRNPDGCLKCFC 926
Score = 86.7 bits (213), Expect = 1e-16
Identities = 51/138 (36%), Positives = 64/138 (46%), Gaps = 16/138 (11%)
Query: 474 PETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDR 533
P EV CPPG G C+ CA GY G + + C+ C+CN + D C
Sbjct: 1522 PRALEVEECRCPPGYIGLSCQDCAPGYTRTGSGLY--LGHCELCECNGHSDL-----CHP 1574
Query: 534 LTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNC---NPMGSEPVGCRSDGT 590
TG C +C HN AG +C+ C GY+GD A P D C+ C C NP C S G
Sbjct: 1575 ETGACSQCQHNAAGEFCELCAPGYYGDATAGTPED-CQPCACPLTNPENMFSRTCESLGA 1633
Query: 591 -----CVCKPGFGGPNCE 603
C+PG+ G CE
Sbjct: 1634 GGYRCTACEPGYTGQYCE 1651
Score = 82.4 bits (202), Expect = 2e-15
Identities = 52/144 (36%), Positives = 68/144 (47%), Gaps = 20/144 (13%)
Query: 484 CPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIH 543
CP G +G CE C + P G + + C C CN + + +CD + G CL C H
Sbjct: 733 CPIGYSGLSCESCDAHFTRVPGGPY--LGTCSGCNCNGH-----ASSCDPVYGHCLNCQH 785
Query: 544 NTAGIYCDQCKAGYFGDPLAPNPADKCRACNC-----NPMGSEPVGCRSDG--TC-VCKP 595
NT G C++CKAG+FGD + A CR C C + S+ +DG TC C P
Sbjct: 786 NTEGPQCNKCKAGFFGDAMKAT-ATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAP 844
Query: 596 GFGGPNCEHGAFSCPACYNQVKIQ 619
G+ G CE SC Y IQ
Sbjct: 845 GYTGRRCE----SCAPGYEGNPIQ 864
Score = 80.1 bits (196), Expect = 1e-14
Identities = 47/140 (33%), Positives = 64/140 (45%), Gaps = 22/140 (15%)
Query: 478 EVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGR 537
EV +CPPG G C+ C GY P G + + C+ C C+ + S C+ TG
Sbjct: 1122 EVEQCSCPPGYRGPSCQDCDTGYTRTPSGLY--LGTCERCSCHGH-----SEACEPETGA 1174
Query: 538 CLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTC------ 591
C C H+T G C+QC+ GY+GD P D C+ C C +P ++ TC
Sbjct: 1175 CQGCQHHTEGPRCEQCQPGYYGDAQRGTPQD-CQLCPCY---GDPAAGQAAHTCFLDTDG 1230
Query: 592 -----VCKPGFGGPNCEHGA 606
C PG G +CE A
Sbjct: 1231 HPTCDACSPGHSGRHCERCA 1250
Score = 35.8 bits (81), Expect = 0.23
Identities = 26/95 (27%), Positives = 37/95 (38%), Gaps = 18/95 (18%)
Query: 458 SCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPC 517
+C+ PC NG C E+ VC CP G TG+RC EH C P
Sbjct: 3847 TCRDRPCQNGGQCHDS-ESSSYVCV-CPAGFTGSRC-------------EHSQALHCHPE 3891
Query: 518 QCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQ 552
C + + N G +C +G+ C++
Sbjct: 3892 ACGPD---ATCVNRPDGRGYTCRCHLGRSGLRCEE 3923
Score = 34.7 bits (78), Expect = 0.52
Identities = 15/43 (34%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Query: 155 CVCKPAVTGERCDRCRSGYYNLDGGNPEG-CTQCFCYGHSASC 196
C C +G C+ C + + + GG G C+ C C GH++SC
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSC 773
Score = 33.9 bits (76), Expect = 0.88
Identities = 28/119 (23%), Positives = 44/119 (36%), Gaps = 21/119 (17%)
Query: 488 VTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAG 547
V G R +L G+ PC+ C + +G + +C+
Sbjct: 4082 VNGKRLDLTYSFLGSQGIGQCYDSSPCERQPCQHGATCMPAGEYE------FQCL----- 4130
Query: 548 IYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGA 606
C+ G+ GD L + + C+ G G R C+C PGF GP C+ G+
Sbjct: 4131 -----CRDGFKGD-LCEHEENPCQLREPCLHGGTCQGTR----CLCLPGFSGPRCQQGS 4179
Score = 32.7 bits (73), Expect = 2.0
Identities = 24/86 (27%), Positives = 28/86 (32%), Gaps = 13/86 (15%)
Query: 412 TCIPCNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYN---DPHDPRSCKPCPCHNGF 468
TC CQ GG C Y CP GF + C P C
Sbjct: 3847 TCRDRPCQNGGQCHDSESSSY---------VCVCPAGFTGSRCEHSQALHCHPEACGPDA 3897
Query: 469 SCSVMPETEEVVCNNCPPGVTGARCE 494
+C P+ C C G +G RCE
Sbjct: 3898 TCVNRPDGRGYTC-RCHLGRSGLRCE 3922
Score = 30.4 bits (67), Expect = 9.7
Identities = 23/80 (28%), Positives = 33/80 (41%), Gaps = 9/80 (11%)
Query: 95 RCDNSGRCSCKPGVTGARCDRCLPG----FHMLTDAGCTQDQ-RLLDSKCDC-DPAGIAG 148
+C +S C +P GA C +P F L G D ++ C +P G
Sbjct: 4101 QCYDSSPCERQPCQHGATC---MPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCLHGG 4157
Query: 149 PCDAGRCVCKPAVTGERCDR 168
C RC+C P +G RC +
Sbjct: 4158 TCQGTRCLCLPGFSGPRCQQ 4177
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 167 bits (424), Expect = 4e-41
Identities = 94/250 (37%), Positives = 124/250 (49%), Gaps = 35/250 (14%)
Query: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-G 434
P QC C G + C C G+ F +C PC C G CDP TG+C +
Sbjct: 835 PVTGQCHCFQGVYARQCDRCLPGH-------WGFPSCQPCQCNGHADDCDPVTGECLNCQ 887
Query: 435 DENPDIECADCPIGFYNDP--HDPRSCKPCPCHNG--------FSCSVMPETEEVVCNNC 484
D C C G+Y DP C+PCPC +G SC P T ++ C C
Sbjct: 888 DYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACV-C 946
Query: 485 PPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHN 544
PG G+RC+ CA GYFG+P G CQPCQC+NN+D + CD+ TGRCLKC+++
Sbjct: 947 DPGYIGSRCDDCASGYFGNPSEVGGS---CQPCQCHNNIDTTDPEACDKETGRCLKCLYH 1003
Query: 545 TAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC--------RSDGTCVCKPG 596
T G +C C+ GY+GD L + CR C CN +G+ C ++ G C+C P
Sbjct: 1004 TEGEHCQFCRFGYYGDALQQD----CRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPN 1059
Query: 597 FGGPNCEHGA 606
G NC+ A
Sbjct: 1060 VIGQNCDRCA 1069
Score = 159 bits (401), Expect = 2e-38
Identities = 184/810 (22%), Positives = 310/810 (38%), Gaps = 113/810 (13%)
Query: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG------GACDPDTGDCYSGD 435
C+C GY G C DCASGY + + +G G+C PC C ACD +TG C
Sbjct: 944 CVCDPGYIGSRCDDCASGYFGNPSEVG--GSCQPCQCHNNIDTTDPEACDKETGRCLKCL 1001
Query: 436 ENPDIE-CADCPIGFYNDPHDPRSCKPCPCH---------NGFSCSVMPETEEVVCNNCP 485
+ + E C C G+Y D + C+ C C+ NG C T + +C
Sbjct: 1002 YHTEGEHCQFCRFGYYGDALQ-QDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCL--- 1057
Query: 486 PGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNT 545
P V G C+ CA + G C PC CN S +C+ TG+C +C+
Sbjct: 1058 PNVIGQNCDRCAPNTWQLASGTG-----CDPCNCN--AAHSFGPSCNEFTGQC-QCMPGF 1109
Query: 546 AGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCE- 603
G C +C+ ++GDP +CRAC+C+P G E C +S G CVC G GP C+
Sbjct: 1110 GGRTCSECQELFWGDPDV-----ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDK 1164
Query: 604 -----HGAF-SCPACYNQVKIQMDQFMQQLQRMEALISKAQG--GDGVV-PDTELEGRMQ 654
G F C C+ + + R + KA+ GV+ P E ++
Sbjct: 1165 CTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRFLEKAKALKISGVIGPYRETVDSVE 1224
Query: 655 QAEQALQDILRDAQISEGASR--------------------SLGLQLAKVRSQENSYQSR 694
+ ++DIL + +E + ++L+ SQ NS
Sbjct: 1225 RKVSEIKDILAQSPAAEPLKNIGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKE 1284
Query: 695 LDDLKMTVE----RVRALGSQYQ----NRVRDTHRLITQ-MQLSLAESEASLGNTNIPAS 745
LD L+ E V+ L Q + + +R IT+ Q+SL E +T P S
Sbjct: 1285 LDSLQTEAESLDNTVKELAEQLEFIKNSDIRGALDSITKYFQMSLEAEERVNASTTEPNS 1344
Query: 746 D--------------HYVGPNGFKSLAQEATRLAES--------HVESASNMEQLTRETE 783
+ FK +E RL + + +A+ M T
Sbjct: 1345 TVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDELAGKLQSLDLSAAAEMTCGTPPGA 1404
Query: 784 DYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQ----------QLTRE 833
S+ EG G G +V +K L Q QL++
Sbjct: 1405 SCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVEQLSKM 1464
Query: 834 ATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFK 893
++A++ AD + Q + +L + + D+S EE + + ++ + + + +D +
Sbjct: 1465 VSEAKLRADEAKQSAEDILLKTNATKEKMDKS--NEELRNLIKQIRNFLTQDSADLDSIE 1522
Query: 894 RTQKNLGNWK-EEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESIL 952
+ + Q LQN + + LS+ + + ++ E +
Sbjct: 1523 AVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRAS 1582
Query: 953 KNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAG 1012
K+ + + D K EEA K + + A + Q + L S ++ ++
Sbjct: 1583 KSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLF 1642
Query: 1013 EALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMD 1072
A + SE+E+ + L +A + A +EK + ++K +V+ L+ E D
Sbjct: 1643 NASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDVKKTLDG---ELDEKYK 1699
Query: 1073 AVQMVITEAQKVDTRAKNAGVTIQDTLNTL 1102
V+ +I + + A+ +Q+ TL
Sbjct: 1700 KVENLIAKKTEESADARRKAEMLQNEAKTL 1729
Score = 115 bits (288), Expect = 2e-25
Identities = 73/212 (34%), Positives = 92/212 (43%), Gaps = 30/212 (14%)
Query: 404 SARLGPFGTCIPCNCQGG--GACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKP 461
SA L G C+ QG CDP+ G C C C G + P CKP
Sbjct: 763 SALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFG--FGPSGCKP 820
Query: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNN 521
C CH S + C +C GV +C+ C G++G P CQPCQCN
Sbjct: 821 CECHLQGSVNAFCNPVTGQC-HCFQGVYARQCDRCLPGHWGFP--------SCQPCQCNG 871
Query: 522 NVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581
+ D +CD +TG CL C T G C++C AGY+GDP+ D CR C C P G +
Sbjct: 872 HAD-----DCDPVTGECLNCQDYTMGHNCERCLAGYYGDPII-GSGDHCRPCPC-PDGPD 924
Query: 582 -----PVGCRSDG-----TCVCKPGFGGPNCE 603
C D CVC PG+ G C+
Sbjct: 925 SGRQFARSCYQDPVTLQLACVCDPGYIGSRCD 956
Score = 114 bits (284), Expect = 7e-25
Identities = 81/234 (34%), Positives = 104/234 (44%), Gaps = 50/234 (21%)
Query: 6 LGCCLCFSLL--LPAARATSRR----EVCDCNGKSRQCIFDRELHRQTGN--GFRCLNCN 57
L C LC LP A R + C+CN S C FD ++ TGN G C +C
Sbjct: 307 LNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQ 366
Query: 58 DNTDGIHCEKCKNGFYRHRERDR-----CLPCNCNSKGSLSAR-CDN---------SGRC 102
NT G +CE+CK +Y+H ERD C C C+ GS + CD+ +G+C
Sbjct: 367 HNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQC 426
Query: 103 SCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLLDSKCDCDPAGI---AGPCDA--GR 154
CK V G CD C GF+ L+ GC C C+P G PCD+ G
Sbjct: 427 RCKLNVEGEHCDVCKEGFYDLSSEDPFGC--------KSCACNPLGTIPGGNPCDSETGH 478
Query: 155 CVCKPAVTGERCDRCRSGYY----NLDGGNPEGC-------TQCFCYGHSASCR 197
C CK VTG+ CD+C ++ +LDG P C CF SCR
Sbjct: 479 CYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCR 532
Score = 99.4 bits (246), Expect = 2e-20
Identities = 73/231 (31%), Positives = 102/231 (44%), Gaps = 41/231 (17%)
Query: 8 CCLC-FSLLLPAARATSRREVCD--------CNGKSRQCIFDRELHRQTGNGFRCLNCND 58
C C F A + R+ VC+ CNG QC + TG +CL C
Sbjct: 1009 CQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQC------DKATG---QCL-CLP 1058
Query: 59 NTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCL 117
N G +C++C ++ C PCNCN+ S C+ +G+C C PG G C C
Sbjct: 1059 NVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQ 1118
Query: 118 PGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYY 174
F D C CDCDP GI P CD G+CVC V G RCD+C GY
Sbjct: 1119 ELFWGDPDVECRA--------CDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGY- 1169
Query: 175 NLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNG 225
G P+ CT C C + + + ++T+ H+ ++ KA++ +G
Sbjct: 1170 --SGVFPD-CTPCH------QCFALWDVIIAELTNRTHRFLEKAKALKISG 1211
Score = 88.6 bits (218), Expect = 3e-17
Identities = 56/160 (35%), Positives = 74/160 (46%), Gaps = 18/160 (11%)
Query: 25 REVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERD--RCL 82
R CD G + I D TG C N +G HC+ CK GFY D C
Sbjct: 397 RCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCK 456
Query: 83 PCNCNSKGSLSA--RCDN-SGRCSCKPGVTGARCDRCLPGFHMLTD--AGCTQDQRLLDS 137
C CN G++ CD+ +G C CK VTG CD+CLP L++ GC
Sbjct: 457 SCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGC--------R 508
Query: 138 KCDCDPAG-IAGPC--DAGRCVCKPAVTGERCDRCRSGYY 174
CDCD G + C ++G+C C+P + G +C+ GYY
Sbjct: 509 PCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
Score = 88.2 bits (217), Expect = 4e-17
Identities = 59/196 (30%), Positives = 86/196 (43%), Gaps = 40/196 (20%)
Query: 28 CDCNGKSRQCI----FDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFY-------RHR 76
C C G + +C F+ E+ C+ C NT G++CE C + ++ R
Sbjct: 271 CFCYGHASECAPVDGFNEEVEGMVHG--HCM-CRHNTKGLNCELCMDFYHDLPWRPAEGR 327
Query: 77 ERDRCLPCNCNSKGSLSARCD----------NSGRCS-CKPGVTGARCDRCLPGFHMLTD 125
+ C CNCN S+S D + G C C+ G C++C P ++ +
Sbjct: 328 NSNACKKCNCNEH-SISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPE 386
Query: 126 AGCTQDQRLLDSKCDCDPAGIA--GPCD----------AGRCVCKPAVTGERCDRCRSGY 173
+D + +C CDPAG G CD AG+C CK V GE CD C+ G+
Sbjct: 387 RDI-RDPNFCE-RCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGF 444
Query: 174 YNLDGGNPEGCTQCFC 189
Y+L +P GC C C
Sbjct: 445 YDLSSEDPFGCKSCAC 460
Score = 83.2 bits (204), Expect = 1e-15
Identities = 69/260 (26%), Positives = 93/260 (35%), Gaps = 56/260 (21%)
Query: 382 CICPVGYKGQFCQDCASGYKRDSARLGP---FGTCIPCNCQ------------------- 419
C+C KG C+ C Y R C CNC
Sbjct: 298 CMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV 357
Query: 420 GGGACDPDTGDCYSGDENPDIECADCPIGFYNDPH----DPRSCKPCPC------HNGFS 469
GG CD DC + C C +Y P DP C+ C C + G
Sbjct: 358 SGGVCD----DCQHNTMGRN--CEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGIC 411
Query: 470 CSVMPETEEVVCNNC--PPGVTGARCELCADGYFG----DPFGEHGPVRPCQPCQCNNNV 523
S + ++ C V G C++C +G++ DPFG C+ C CN
Sbjct: 412 DSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFG-------CKSCACNPLG 464
Query: 524 DPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPV 583
CD TG C C G +CDQC ++G N D CR C+C+ G+
Sbjct: 465 TIPGGNPCDSETGHCY-CKRLVTGQHCDQCLPEHWG---LSNDLDGCRPCDCDLGGALNN 520
Query: 584 GCRSD-GTCVCKPGFGGPNC 602
C ++ G C C+P G C
Sbjct: 521 SCFAESGQCSCRPHMIGRQC 540
Score = 81.3 bits (199), Expect = 5e-15
Identities = 63/204 (30%), Positives = 89/204 (43%), Gaps = 37/204 (18%)
Query: 429 GDCYSGDENPDIECADCPIGFYND----PHDPRS---CKPCPCHNG-----FSCSVMPET 476
G C + C C + FY+D P + R+ CK C C+ F +V T
Sbjct: 296 GHCMCRHNTKGLNCELC-MDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
Query: 477 EEV---VCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGN--- 530
V VC++C G CE C Y+ P + C+ C C DP+ S N
Sbjct: 355 GNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTC----DPAGSQNEGI 410
Query: 531 CDRLT--------GRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEP 582
CD T G+C +C N G +CD CK G++ L+ C++C CNP+G+ P
Sbjct: 411 CDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFY--DLSSEDPFGCKSCACNPLGTIP 467
Query: 583 VG--CRSD-GTCVCKPGFGGPNCE 603
G C S+ G C CK G +C+
Sbjct: 468 GGNPCDSETGHCYCKRLVTGQHCD 491
Score = 80.5 bits (197), Expect = 8e-15
Identities = 42/119 (35%), Positives = 57/119 (47%), Gaps = 17/119 (14%)
Query: 82 LPCNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCD 140
L C C+ +GSLS+ CD N G+C C+P V G C+RC PG +GC C+
Sbjct: 771 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGC--------KPCE 822
Query: 141 CDPAG-IAGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASC 196
C G + C+ G+C C V +CDRC G++ C C C GH+ C
Sbjct: 823 CHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGF-----PSCQPCQCNGHADDC 876
Score = 77.4 bits (189), Expect = 7e-14
Identities = 49/144 (34%), Positives = 67/144 (46%), Gaps = 15/144 (10%)
Query: 49 NGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPG 107
NG +C C N G C +C G + C PC C+ +GS++A C+ +G+C C G
Sbjct: 788 NGGQC-QCRPNVVGRTCNRCAPGTFGFGPSG-CKPCECHLQGSVNAFCNPVTGQCHCFQG 845
Query: 108 VTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCV-CKPAVTGERC 166
V +CDRCLPG Q D DCDP G C+ C+ G C
Sbjct: 846 VYARQCDRCLPGHWGFPSCQPCQCNGHAD---DCDPV-------TGECLNCQDYTMGHNC 895
Query: 167 DRCRSGYY-NLDGGNPEGCTQCFC 189
+RC +GYY + G+ + C C C
Sbjct: 896 ERCLAGYYGDPIIGSGDHCRPCPC 919
Score = 75.9 bits (185), Expect = 2e-13
Identities = 63/208 (30%), Positives = 80/208 (38%), Gaps = 40/208 (19%)
Query: 7 GCCLCFSLL--------LPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCND 58
G C CF + LP + C CNG + C TG CLNC D
Sbjct: 838 GQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDC------DPVTGE---CLNCQD 888
Query: 59 NTDGIHCEKCKNGFYRH---RERDRCLPCNC----NSKGSLSARCDNSG-----RCSCKP 106
T G +CE+C G+Y D C PC C +S + C C C P
Sbjct: 889 YTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDP 948
Query: 107 GVTGARCDRCLPGF--HMLTDAGCTQDQRLLDSKCDCDPAGIAGPCD--AGRCV-CKPAV 161
G G+RCD C G+ + G Q + ++ DP CD GRC+ C
Sbjct: 949 GYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEA----CDKETGRCLKCLYHT 1004
Query: 162 TGERCDRCRSGYYNLDGGNPEGCTQCFC 189
GE C CR GYY + C +C C
Sbjct: 1005 EGEHCQFCRFGYYG--DALQQDCRKCVC 1030
Score = 65.1 bits (157), Expect = 4e-10
Identities = 44/155 (28%), Positives = 63/155 (40%), Gaps = 16/155 (10%)
Query: 353 GEYSTGYIDNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGT 412
G + G D+ T S ++G QC C + +G+ C C G+ D + PFG
Sbjct: 404 GSQNEGICDSYTDFSTGLIAG-------QCRCKLNVEGEHCDVCKEGFY-DLSSEDPFG- 454
Query: 413 CIPCNCQ------GGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHN 466
C C C GG CD +TG CY C C + +D C+PC C
Sbjct: 455 CKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDL 514
Query: 467 GFSCSVMPETEEVVCNNCPPGVTGARCELCADGYF 501
G + + E C +C P + G +C GY+
Sbjct: 515 GGALNNSCFAESGQC-SCRPHMIGRQCNEVEPGYY 548
Score = 53.5 bits (127), Expect = 1e-06
Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 2/71 (2%)
Query: 56 CNDNTDGIHCEKCKNGFYR-HRERDRCLPCNCNSKGSLSARC-DNSGRCSCKPGVTGARC 113
C G HC++C + + D C PC+C+ G+L+ C SG+CSC+P + G +C
Sbjct: 481 CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQC 540
Query: 114 DRCLPGFHMLT 124
+ PG++ T
Sbjct: 541 NEVEPGYYFAT 551
Score = 38.9 bits (89), Expect = 0.027
Identities = 27/88 (30%), Positives = 33/88 (37%), Gaps = 13/88 (14%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG----ACDPDTGD--CYSG 434
QC C G+ G+ C +C + D P C C+C G CD TG C G
Sbjct: 1102 QCQCMPGFGGRTCSECQELFWGD-----PDVECRACDCDPRGIETPQCDQSTGQCVCVEG 1156
Query: 435 DENPDIECADCPIGFYNDPHDPRSCKPC 462
E P C C G+ D C C
Sbjct: 1157 VEGP--RCDKCTRGYSGVFPDCTPCHQC 1182
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 159 bits (402), Expect = 1e-38
Identities = 89/247 (36%), Positives = 113/247 (45%), Gaps = 36/247 (14%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-GDENP 438
QC+C G G C C G F +C PC C G C+ TG C D
Sbjct: 849 QCLCRTGAFGLRCDRCQRGQ-------WGFPSCRPCVCNGHADECNTHTGACLGCRDHTG 901
Query: 439 DIECADCPIGFYNDPHDPRS--CKPCPC--------HNGFSCSVMPETEEVVCNNCPPGV 488
C C GF+ DP P C+PCPC H SC ++++VC+ C G
Sbjct: 902 GEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCH-CRAGY 960
Query: 489 TGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGI 548
TG RCE CA G+FGDP G CQ C+C+ N+DP CD TG+CL+C+H+T G
Sbjct: 961 TGLRCEACAPGHFGDPSRPGGR---CQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGP 1017
Query: 549 YCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC---------RSDGTCVCKPGFGG 599
+C CK G+ G C C CN +G+ P C S G C C P G
Sbjct: 1018 HCAHCKPGFHGQA----ARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQG 1073
Query: 600 PNCEHGA 606
P+C+ A
Sbjct: 1074 PSCDRCA 1080
Score = 122 bits (305), Expect = 2e-27
Identities = 171/750 (22%), Positives = 279/750 (37%), Gaps = 113/750 (15%)
Query: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG------GACDPDTGDCYS-- 433
C C GY G C+ CA G+ D +R P G C C C G ACDP TG C
Sbjct: 954 CHCRAGYTGLRCEACAPGHFGDPSR--PGGRCQLCECSGNIDPMDPDACDPHTGQCLRCL 1011
Query: 434 -GDENPDIECADCPIGFYNDPHDPRSCKPCPCHN-GFSCSVMPETEEVVCN----NCP-- 485
E P CA C GF+ +SC C C+ G + P ++ C+ CP
Sbjct: 1012 HHTEGP--HCAHCKPGFHGQAAR-QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCL 1068
Query: 486 PGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNT 545
P V G C+ CA ++ G HG CQPC C+ + + C+ TG+C C
Sbjct: 1069 PNVQGPSCDRCAPNFWNLTSG-HG----CQPCACHPS--RARGPTCNEFTGQC-HCRAGF 1120
Query: 546 AGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH 604
G C +C+ ++GDP +C AC+C+ G + C R G C C+PG G C+
Sbjct: 1121 GGRTCSECQELHWGDP-----GLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQ 1175
Query: 605 GA--FS--------CPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQ 654
A FS C AC+ + + QR+E + Q T + G +
Sbjct: 1176 CARGFSGIFPACHPCHACFGDWDRVVQDLAARTQRLEQRAQELQ-------QTGVLGAFE 1228
Query: 655 QAEQALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQN 714
+ +Q+ LG+ V ++ S S ++ T E R +G ++
Sbjct: 1229 SSFWHMQE-------------KLGIVQGIVGARNTSAASTAQLVEATEELRREIGEATEH 1275
Query: 715 RVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEAT-RLAESHVE--S 771
+TQ++ L + + N N H + LA T R + H++
Sbjct: 1276 --------LTQLEADLTDVQDENFNAN-----HALSGLERDRLALNLTLRQLDQHLDLLK 1322
Query: 772 ASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLT 831
SN Q+ R+A + S + A + E L +
Sbjct: 1323 HSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEALMDAQKEDFNSK 1382
Query: 832 REATQAEIEADRSYQHSLRLLD----------------SVSRLQGVSDQSFQVEEAKRIK 875
A Q + ++ H+L L D S G D+ Q
Sbjct: 1383 HMANQRALGKLSAHTHTLSLTDINELVCGAPGDAPCATSPCGGAGCRDEDGQPRCGGLSC 1442
Query: 876 QKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQ 935
A + + L + + TQ E Q+ L G S + + +A+ A+ RAQ
Sbjct: 1443 NGAAATADLA---LGRARHTQ-------AELQRALAEGGSILSRVAETRRQASEAQQRAQ 1492
Query: 936 EALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAER 995
AL NA+ +VE + L+E V + + + ++ +V + S AE+
Sbjct: 1493 AALDKANASRGQVEQANQELQELIQSVKDFLNQEGADPDSIEMVATRVLELSIPA-SAEQ 1551
Query: 996 ALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMRE 1055
A A A+R ++ A ++ + + + +G + + D A K +
Sbjct: 1552 IQHLAGAIAERVRSLA----DVDAILARTVGDVRRAEQLLQDARRA-RSWAEDEKQKAET 1606
Query: 1056 VEGELERKELEFDTNMDAVQMVITEAQKVD 1085
V+ LE + A++ + + + +
Sbjct: 1607 VQAALEEAQRAQGIAQGAIRGAVADTRDTE 1636
Score = 114 bits (284), Expect = 7e-25
Identities = 68/184 (36%), Positives = 89/184 (48%), Gaps = 28/184 (15%)
Query: 28 CDCNGKSRQCIFDRELHRQTGN--GFRCLNCNDNTDGIHCEKCKNGFYRHRERDR----- 80
C+C+G + C FD ++ +GN G C C NT G HCE C+ FYR +D
Sbjct: 347 CECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAV 406
Query: 81 CLPCNCNSKGSLSA-RCDN---------SGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQ 130
C C+C+ GS RCD+ SG+C CK V G RC +C GF G +
Sbjct: 407 CRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFF-----GLSI 461
Query: 131 DQRLLDSKCDCDPAGI---AGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCT 185
RL +C C+ G + PCD +G C CK VTG CDRC G++ L + GC
Sbjct: 462 SDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGL-SHDLLGCR 520
Query: 186 QCFC 189
C C
Sbjct: 521 PCDC 524
Score = 97.4 bits (241), Expect = 6e-20
Identities = 46/121 (38%), Positives = 64/121 (52%), Gaps = 17/121 (14%)
Query: 82 LPCNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCD 140
LPC CN +GSLS+ C+ + G+C CKPGV G RCD C PG++ GC C
Sbjct: 781 LPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGC--------QACQ 832
Query: 141 CDPAG-IAGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCR 197
C G ++ C+ +G+C+C+ G RCDRC+ G + C C C GH+ C
Sbjct: 833 CSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGF-----PSCRPCVCNGHADECN 887
Query: 198 S 198
+
Sbjct: 888 T 888
Score = 95.1 bits (235), Expect = 3e-19
Identities = 69/227 (30%), Positives = 87/227 (38%), Gaps = 62/227 (27%)
Query: 19 ARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRER 78
+R R ++C+C+G D TG +CL C +T+G HC CK GF+ R
Sbjct: 977 SRPGGRCQLCECSGNIDPMDPDA-CDPHTG---QCLRCLHHTEGPHCAHCKPGFHGQAAR 1032
Query: 79 DRCLPCNCNSKGSLSARCDN---------SGRCSCKPGVTGARCDRCLPGFHMLTDA-GC 128
C C CN G+ +C + SG+C C P V G CDRC P F LT GC
Sbjct: 1033 QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGC 1092
Query: 129 TQ----------------------------------------DQRLLDSKCDCDPAGIAG 148
D L CDCD GI
Sbjct: 1093 QPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDT 1152
Query: 149 P-CD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCF-CYG 191
P C G C C+P V+G RCD+C G+ G C C C+G
Sbjct: 1153 PQCHRFTGHCSCRPGVSGVRCDQCARGF----SGIFPACHPCHACFG 1195
Score = 93.2 bits (230), Expect = 1e-18
Identities = 58/160 (36%), Positives = 80/160 (50%), Gaps = 22/160 (13%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGF---RCLNCNDNTDGIHCEKCKNGFYRHRERDR--CL 82
CDC+ Q + H G +C C ++ G C++C++GF+ DR C
Sbjct: 410 CDCDPMGSQDGGRCDSHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFGLSISDRLGCR 468
Query: 83 PCNCNSKGSL--SARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTD--AGCTQDQRLLDS 137
C CN++G++ S CD NSG C CK VTG CDRCLPG L+ GC
Sbjct: 469 RCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGC--------R 520
Query: 138 KCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYY 174
CDCD G P CD G+C C+ + G RC++ + GY+
Sbjct: 521 PCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 85.5 bits (210), Expect = 3e-16
Identities = 75/273 (27%), Positives = 97/273 (35%), Gaps = 52/273 (19%)
Query: 370 PVSGAPAPWVEQ----CICPVGYKGQFCQDCASGYKR---DSARLGPFGTCIPCNCQG-- 420
P GAPA CIC +G C+ C Y+ A G C C C G
Sbjct: 294 PAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHT 353
Query: 421 -----------------GGACDPDTGDCYSGDENPDIECADCPIGFYNDP----HDPRSC 459
GG CD C C C FY DP DP C
Sbjct: 354 HSCHFDMAVYLASGNVSGGVCD----GCQHNTAGR--HCELCRPFFYRDPTKDLRDPAVC 407
Query: 460 KPCPC-----HNGFSCSVMPETEEVVCN---NCPPGVTGARCELCADGYFGDPFGEHGPV 511
+ C C +G C + + + C V G RC+ C DG+FG +
Sbjct: 408 RSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDR--- 464
Query: 512 RPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCR 571
C+ CQCN S CD +G C C G CD+C G++G + CR
Sbjct: 465 LGCRRCQCNARGTVPGSTPCDPNSGSCY-CKRLVTGRGCDRCLPGHWG---LSHDLLGCR 520
Query: 572 ACNCNPMGS-EPVGCRSDGTCVCKPGFGGPNCE 603
C+C+ G+ +P G C C+ G CE
Sbjct: 521 PCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCE 553
Score = 84.3 bits (207), Expect = 6e-16
Identities = 54/145 (37%), Positives = 73/145 (50%), Gaps = 22/145 (15%)
Query: 461 PCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCN 520
PC C+ S S C C PGV G RC+LCA GY+G FG G CQ CQC+
Sbjct: 782 PCQCNPQGSLSSECNPHGGQCL-CKPGVVGRRCDLCAPGYYG--FGPTG----CQACQCS 834
Query: 521 NNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGS 580
+ + + S C++ +G+CL C G+ CD+C+ G +G P CR C CN
Sbjct: 835 H--EGALSSLCEKTSGQCL-CRTGAFGLRCDRCQRGQWGFP-------SCRPCVCNGHAD 884
Query: 581 EPVGCRS-DGTCV-CKPGFGGPNCE 603
E C + G C+ C+ GG +CE
Sbjct: 885 E---CNTHTGACLGCRDHTGGEHCE 906
Score = 77.4 bits (189), Expect = 7e-14
Identities = 60/206 (29%), Positives = 80/206 (38%), Gaps = 54/206 (26%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFY---RHRERDRCLPC 84
C CNG + +C + TG CL C D+T G HCE+C GF+ R +C PC
Sbjct: 877 CVCNGHADEC------NTHTG---ACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPC 927
Query: 85 NC----NSKGSLSARCDNSGR-----CSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLL 135
C S+ + C C C+ G TG RC+ C PG D
Sbjct: 928 PCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHF--------GDPSRP 979
Query: 136 DSKCD-CDPAGIAGPCD-------AGRCV-CKPAVTGERCDRCRSGYY------------ 174
+C C+ +G P D G+C+ C G C C+ G++
Sbjct: 980 GGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCT 1039
Query: 175 -NLDGGNPEGC---TQCFCYGHSASC 196
NL G NP+ C QC C S C
Sbjct: 1040 CNLLGTNPQQCPSPDQCHCDPSSGQC 1065
Score = 73.6 bits (179), Expect = 1e-12
Identities = 56/196 (28%), Positives = 81/196 (41%), Gaps = 40/196 (20%)
Query: 28 CDCNGKSRQCIF--DRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR--------E 77
C C G + +C H + C+ C NT G++CE+C++ FYR
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQD-FYRDLPWRPAEDGH 340
Query: 78 RDRCLPCNCNSKGS---------LSARCDNSGRCS-CKPGVTGARCDRCLPGFHMLTDAG 127
C C C+ L++ + G C C+ G C+ C P F+
Sbjct: 341 SHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYR----D 396
Query: 128 CTQDQR--LLDSKCDCDPAGI--AGPCDA----------GRCVCKPAVTGERCDRCRSGY 173
T+D R + CDCDP G G CD+ G+C CK V G RC +CR G+
Sbjct: 397 PTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGF 456
Query: 174 YNLDGGNPEGCTQCFC 189
+ L + GC +C C
Sbjct: 457 FGLSISDRLGCRRCQC 472
Score = 70.5 bits (171), Expect = 8e-12
Identities = 54/171 (31%), Positives = 74/171 (43%), Gaps = 33/171 (19%)
Query: 28 CDCNGK---SRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPC 84
C CN + S +C +G +CL C G C+ C G+Y C C
Sbjct: 783 CQCNPQGSLSSEC---------NPHGGQCL-CKPGVVGRRCDLCAPGYYGFGPTG-CQAC 831
Query: 85 NCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDP 143
C+ +G+LS+ C+ SG+C C+ G G RCDRC G Q S C
Sbjct: 832 QCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRG------------QWGFPSCRPCVC 879
Query: 144 AGIAGPCD--AGRCV-CKPAVTGERCDRCRSGYYNLDGGNPEG--CTQCFC 189
G A C+ G C+ C+ GE C+RC +G++ D P G C C C
Sbjct: 880 NGHADECNTHTGACLGCRDHTGGEHCERCIAGFHG-DPRLPYGGQCRPCPC 929
Score = 66.2 bits (160), Expect = 2e-10
Identities = 58/226 (25%), Positives = 88/226 (38%), Gaps = 34/226 (15%)
Query: 352 YGEYSTGYIDNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSAR-LGPF 410
+G + + D +++ VSG C G+ C+ C + RD + L
Sbjct: 350 HGHTHSCHFDMAVYLASGNVSGGVCDG-----CQHNTAGRHCELCRPFFYRDPTKDLRDP 404
Query: 411 GTCIPCNC-----QGGGACDPD--------TGDCYSGDENPDIECADCPIGFYN-DPHDP 456
C C+C Q GG CD +G C + C C GF+ D
Sbjct: 405 AVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDR 464
Query: 457 RSCKPCPCHNGFSCSVMPETEEVVCNN----CPPGVTGARCELCADGYFGDPFGEHGPVR 512
C+ C C+ + +P + N+ C VTG C+ C G++G G
Sbjct: 465 LGCRRCQCN---ARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLG--- 518
Query: 513 PCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
C+PC C+ V + CD TG+C C + G C+Q + GYF
Sbjct: 519 -CRPCDCD--VGGALDPQCDEGTGQC-HCRQHMVGRRCEQVQPGYF 560
Score = 63.2 bits (152), Expect = 1e-09
Identities = 44/136 (32%), Positives = 54/136 (39%), Gaps = 14/136 (10%)
Query: 381 QCICPVGYKGQFCQDCASGY--KRDSARLGPFGTCIPCNCQGGGA------CDPDTGDCY 432
QC C G CQ C G+ S RLG C C C G CDP++G CY
Sbjct: 437 QCRCKEHVVGTRCQQCRDGFFGLSISDRLG----CRRCQCNARGTVPGSTPCDPNSGSCY 492
Query: 433 SGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGAR 492
C C G + HD C+PC C G + + C +C + G R
Sbjct: 493 CKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQC-HCRQHMVGRR 551
Query: 493 CELCADGYFGDPFGEH 508
CE GYF PF +H
Sbjct: 552 CEQVQPGYF-RPFLDH 566
Score = 53.1 bits (126), Expect = 1e-06
Identities = 40/141 (28%), Positives = 55/141 (39%), Gaps = 15/141 (10%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG----GGACDPDTGDCYSGDE 436
QC C +G C CA + ++ G C PC C G C+ TG C+
Sbjct: 1064 QCPCLPNVQGPSCDRCAPNFWNLTSGHG----CQPCACHPSRARGPTCNEFTGQCHCRAG 1119
Query: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
C++C + DP C C C + + C+ C PGV+G RC+ C
Sbjct: 1120 FGGRTCSECQELHWGDPG--LQCHACDCDSRGIDTPQCHRFTGHCS-CRPGVSGVRCDQC 1176
Query: 497 ADGYFGDPFGEHGPVRPCQPC 517
A G+ G H PC C
Sbjct: 1177 ARGFSGIFPACH----PCHAC 1193
Score = 53.1 bits (126), Expect = 1e-06
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 19/105 (18%)
Query: 17 PAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR 76
P A SR CN + QC +C G C +C+ +
Sbjct: 1094 PCACHPSRARGPTCNEFTGQC-----------------HCRAGFGGRTCSECQELHWGDP 1136
Query: 77 ERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGF 120
+C C+C+S+G + +C +G CSC+PGV+G RCD+C GF
Sbjct: 1137 GL-QCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGF 1180
Score = 43.5 bits (101), Expect = 0.001
Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 5/49 (10%)
Query: 153 GRCVCKPAVTGERCDRCRSGYYNL-----DGGNPEGCTQCFCYGHSASC 196
G C+CK G C++C+ Y +L + G+ C +C C+GH+ SC
Sbjct: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSC 356
Score = 41.2 bits (95), Expect = 0.006
Identities = 66/296 (22%), Positives = 122/296 (41%), Gaps = 42/296 (14%)
Query: 814 QGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRL-LDSVSRLQGVSDQSFQVEEAK 872
Q L E ++ K Q + E+ A R + S+ + + L G A+
Sbjct: 1510 QELQELIQSVKDFLNQEGADPDSIEMVATRVLELSIPASAEQIQHLAGAI--------AE 1561
Query: 873 RIKQKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGR---EKSDQLLSRANL 929
R++ AD + +++ R + + +R A+QLLQ+ + R E Q
Sbjct: 1562 RVRSLAD-VDAILARTVGDVRR-----------AEQLLQDARRARSWAEDEKQKAETVQA 1609
Query: 930 AKSRAQEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDK 989
A AQ A + + ++ + QV R A AE A+ ++++ DA +
Sbjct: 1610 ALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQL-DALLE 1668
Query: 990 TQQAERALGSAAADAQRAKNGAGEALEISSEIEQ--------EIGSLNLEANVTADGALA 1041
+ +RA S AA A+ AG A + E EQ + ++ A A G LA
Sbjct: 1669 ALKLKRAGNSLAAST--AEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLA 1726
Query: 1042 MEKGLASLKSEMREV----EGELER-KELE--FDTNMDAVQMVITEAQKVDTRAKN 1090
+ L+ E R++ + +L+R +ELE ++ N A++ + ++ R ++
Sbjct: 1727 AQARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARMRS 1782
Score = 36.2 bits (82), Expect = 0.18
Identities = 20/72 (27%), Positives = 29/72 (40%), Gaps = 10/72 (13%)
Query: 508 HGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAP--- 564
+G C P P A + + + C HNT G+ C+QC+ Y P P
Sbjct: 286 YGHASECAPA-------PGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAED 338
Query: 565 NPADKCRACNCN 576
+ CR C C+
Sbjct: 339 GHSHACRKCECH 350
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 158 bits (399), Expect = 3e-38
Identities = 83/233 (35%), Positives = 114/233 (48%), Gaps = 26/233 (11%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-GDENP 438
QC C G+ C C +GY F +C PC C CDP+TG C++ G
Sbjct: 835 QCPCHGEVSGRRCDRCLAGYFG-------FPSCHPCPCNRFAELCDPETGSCFNCGGFTT 887
Query: 439 DIECADCPIGFYNDPHDPRSCKPCPCHN--------GFSCSVMPETEEVVCNNCPPGVTG 490
C C G+Y +P + C+PC C + SC + +V+CN C G TG
Sbjct: 888 GRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICN-CLQGYTG 946
Query: 491 ARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYC 550
+C C+ G++G+P P CQPC CNNN+D + +C R+TG CL+C+HNT G C
Sbjct: 947 TQCGECSTGFYGNPRISGAP---CQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANC 1003
Query: 551 DQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNC 602
CK G++G L CR C+C+ G P+ C G C+C P G C
Sbjct: 1004 QLCKPGHYGSAL----NQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPC 1052
Score = 136 bits (342), Expect = 1e-31
Identities = 178/807 (22%), Positives = 316/807 (39%), Gaps = 159/807 (19%)
Query: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG------GACDPDTGDCYSGD 435
C C GY G C +C++G+ + G C PC C +C TG+C
Sbjct: 938 CNCLQGYTGTQCGECSTGFYGNPRISG--APCQPCACNNNIDVTDPESCSRVTGECLRCL 995
Query: 436 ENPD-IECADCPIGFYNDPHDPRSCKPCPCH-----------NGFSCSVMPETEEVVCNN 483
N C C G Y + ++C+ C CH G +C P T C
Sbjct: 996 HNTQGANCQLCKPGHYGSALN-QTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCL- 1053
Query: 484 CPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIH 543
P VTG C+ CADGY+ P R CQ C C+ S S +CD+LTG+C C
Sbjct: 1054 --PNVTGLACDRCADGYW-----NLVPGRGCQSCDCDPRT--SQSSHCDQLTGQC-PCKL 1103
Query: 544 NTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD-GTCVCKPGFGGPNC 602
G C +C+ Y+GD P +C C+CN G++ C D G C C+ G G C
Sbjct: 1104 GYGGKRCSECQENYYGD-----PPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRC 1158
Query: 603 EHGA----------FSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTE---- 648
+ A C C++Q + + +Q + L + + +P E
Sbjct: 1159 DRCARGHSQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAANMEDKRETLPVCEADFK 1218
Query: 649 -LEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRL------DDLKMT 701
L G + + E+ IL+ G + VR Q +L DLK T
Sbjct: 1219 DLRGNVSEIER----ILKHPVFPSGKFLKVKDYHDSVRRQIMQLNEQLKAVYEFQDLKDT 1274
Query: 702 VERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEA 761
+ER + + L+ +Q + + L + +S++ S A++
Sbjct: 1275 IERAK----------NEADLLLEDLQEEIDLQSSVLNASIADSSENIKKYYHISSSAEKK 1324
Query: 762 TRLAESHVESASNM--EQLTRETEDYSKQALSLVR---------KALHEGVGSGSGSP-- 808
S + +++N + LT SK LSL R + L+E V G+
Sbjct: 1325 INETSSTINTSANTRNDLLTILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGDPGNVPC 1384
Query: 809 -----DGAVVQG---------------------LVEKLEKTKSLAQQLTREA----TQAE 838
GA+ G ++K ++ KS+ + L ++ Q E
Sbjct: 1385 VPLPCGGALCTGRKGHRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLKNQIE 1444
Query: 839 I---EADRSYQHSLRLLDSVSRLQGVSD-------------QSFQVEE---AKRIKQKAD 879
+A+ S ++L+L + + ++ SD ++F +EE + I++ A+
Sbjct: 1445 SISEQAEVSKNNALQLREKLGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIEKVAN 1504
Query: 880 SLSSL---------------VTRHM---DEFKRTQKNLGNWKEEAQQLLQNGKSGREKSD 921
+ + + +HM ++++ + L + AQ+LL K+ + ++
Sbjct: 1505 GVLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENRLNEEADGAQKLLVKAKAAEKAAN 1564
Query: 922 QLLSRANLAKSRAQEALSMG--NATFYEVESILKNLREFDLQVDNRKAEAE---EAMKRL 976
LL+ Q ++ G N+T ++ + + +++ LQ +N+ E + E K+
Sbjct: 1565 ILLNLDKTLNQLQQAQITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELELAKQR 1624
Query: 977 SYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANVTA 1036
S + +S K Q+ + +A A+ A++ AG + E++++ L + + T
Sbjct: 1625 SGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKEFVELKKQYAILQRKTSTTG 1684
Query: 1037 DGALAMEKGLASLKSEMREVEGELERK 1063
+ K + LK ++ G+ E K
Sbjct: 1685 LTKETLGK-VKQLKDAAEKLAGDTEAK 1710
Score = 114 bits (286), Expect = 4e-25
Identities = 62/183 (33%), Positives = 90/183 (49%), Gaps = 27/183 (14%)
Query: 28 CDCNGKSRQCIFDRELHRQTG--NGFRCLNCNDNTDGIHCEKCKNGFYRHRERD-----R 80
C CN S +C FD + +G +G C +C NT+G HC++C+ FYR +
Sbjct: 332 CSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYA 391
Query: 81 CLPCNCNSKGSLS----------ARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQ 130
C+PC C+ G++S A +G+C CK V GA+CD+C P + G +
Sbjct: 392 CIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHY-----GLSA 446
Query: 131 DQRLLDSKCDCDPAG----IAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQ 186
L CDC+P G + D G+C+C VTG C+ C GY+ L G + GC+
Sbjct: 447 TDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGL-GNHLHGCSP 505
Query: 187 CFC 189
C C
Sbjct: 506 CDC 508
Score = 113 bits (283), Expect = 9e-25
Identities = 81/237 (34%), Positives = 110/237 (46%), Gaps = 33/237 (13%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
QC C G+ C C++G S LG G C PC+C G+ CD TG C E
Sbjct: 787 QCQCKPLVVGRCCDRCSTG----SYDLGHHG-CHPCHCHPQGSKDTVCDQVTGQCPCHGE 841
Query: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
C C G++ P SC PCPC N F+ PET C NC TG CE C
Sbjct: 842 VSGRRCDRCLAGYFGFP----SCHPCPC-NRFAELCDPETGS--CFNCGGFTTGRNCERC 894
Query: 497 ADGYFGDPFGEHGPVRPCQPCQCNNNVDPSA----SGNCDR---LTGRCLKCIHNTAGIY 549
DGY+G+P +PC+PC C + DPS+ + +C + + C+ G
Sbjct: 895 IDGYYGNP----SSGQPCRPCLCPD--DPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQ 948
Query: 550 CDQCKAGYFGDP-LAPNPADKCRACNCNPMGSEPVGC-RSDGTCV-CKPGFGGPNCE 603
C +C G++G+P ++ P C ACN N ++P C R G C+ C G NC+
Sbjct: 949 CGECSTGFYGNPRISGAPCQPC-ACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQ 1004
Score = 96.3 bits (238), Expect = 1e-19
Identities = 60/177 (33%), Positives = 75/177 (42%), Gaps = 31/177 (17%)
Query: 28 CDCNGKSRQCIFDRE-LHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNC 86
C CN + D E R TG CL C NT G +C+ CK G Y C C+C
Sbjct: 970 CACNNNID--VTDPESCSRVTGE---CLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSC 1024
Query: 87 NSKGSLSARCDN----------SGRCSCKPGVTGARCDRCLPGF-HMLTDAGCTQDQRLL 135
++ G C +G C C P VTG CDRC G+ +++ GC
Sbjct: 1025 HASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGC------- 1077
Query: 136 DSKCDCDP-AGIAGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
CDCDP + CD G+C CK G+RC C+ YY G P C C C
Sbjct: 1078 -QSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYY---GDPPGRCIPCDC 1130
Score = 91.7 bits (226), Expect = 4e-18
Identities = 64/202 (31%), Positives = 89/202 (44%), Gaps = 43/202 (21%)
Query: 25 REVCDCNGKSRQCIFDRELHRQTGNGF--------RCLNCNDNTDGIHCEKCKNGFYRHR 76
R C CNG + +C R + + G+ F +C+ C NTDG +CE+CK+ F
Sbjct: 262 RGSCFCNGHASEC---RPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAP 317
Query: 77 ER-------DRCLPCNCNSKGS---------LSARCDNSGRCS-CKPGVTGARCDRCLPG 119
R + C C+CNS S L++ + G C C+ G CDRC P
Sbjct: 318 WRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPL 377
Query: 120 FHMLTDAGCTQDQRLLDSKCDCDPAGI--AGPCD----------AGRCVCKPAVTGERCD 167
F+ D T C+CDP G G C AG+C+CK V G +CD
Sbjct: 378 FYR--DPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCD 435
Query: 168 RCRSGYYNLDGGNPEGCTQCFC 189
+C+ +Y L +P GC C C
Sbjct: 436 QCKPNHYGLSATDPLGCQPCDC 457
Score = 90.5 bits (223), Expect = 8e-18
Identities = 75/266 (28%), Positives = 100/266 (37%), Gaps = 59/266 (22%)
Query: 381 QCICPVGYKGQFCQDCASGYK----RDSARLGPFGTCIPCNCQG---------------- 420
QC+C G C+ C ++ R +A L C C+C
Sbjct: 294 QCVCQHNTDGPNCERCKDFFQDAPWRPAADLQD-NACRSCSCNSHSSRCHFDMTTYLASG 352
Query: 421 ---GGACDPDTGDCYSGDENPDIECADCPIGFYNDP----HDPRSCKPCPCH------NG 467
GG C+ DC E C C FY DP DP +C PC C G
Sbjct: 353 GLSGGVCE----DCQHNTEGQ--HCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGG 406
Query: 468 FSCSVMPETEEVVCNNC--PPGVTGARCELCADGYFG----DPFGEHGPVRPCQPCQCNN 521
S V C V GA+C+ C ++G DP G CQPC CN
Sbjct: 407 ICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLG-------CQPCDCNP 459
Query: 522 NVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581
+ CD TG+CL C+ G +C++C GY+G N C C+C+ G+
Sbjct: 460 -LGSLPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWG---LGNHLHGCSPCDCDIGGAY 514
Query: 582 PVGCR-SDGTCVCKPGFGGPNCEHGA 606
C +G C C+P G +C A
Sbjct: 515 SNVCSPKNGQCECRPHVTGRSCSEPA 540
Score = 85.5 bits (210), Expect = 3e-16
Identities = 49/162 (30%), Positives = 74/162 (45%), Gaps = 20/162 (12%)
Query: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
C N G+ C++C +G++ C C+C+ + S S+ CD +G+C CK G G RC
Sbjct: 1052 CLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCS 1111
Query: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPC---DAGRCVCKPAVTGERCDRCRS 171
C ++ C CDC+ AG P D G C C+ V+G+RCDRC
Sbjct: 1112 ECQENYYGDPPGRCIP--------CDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCAR 1163
Query: 172 GYYNLDGGNPEGCTQC-FCY---GHSASCRSSAEYSVHKITS 209
G+ C QC C+ H+ S S A + ++ +
Sbjct: 1164 GH----SQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAA 1201
Score = 82.4 bits (202), Expect = 2e-15
Identities = 48/157 (30%), Positives = 71/157 (45%), Gaps = 17/157 (10%)
Query: 79 DRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDS 137
D + C C+ +GS+ + C G+C CKP V G CDRC G + L GC
Sbjct: 764 DGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGC--------H 815
Query: 138 KCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQC--FCYGH 192
C C P G CD G+C C V+G RCDRC +GY+ +P C + C
Sbjct: 816 PCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPE 875
Query: 193 SASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAK 229
+ SC + ++ + + +DG+ +G P +
Sbjct: 876 TGSCFNCGGFTTGR---NCERCIDGYYGNPSSGQPCR 909
Score = 80.1 bits (196), Expect = 1e-14
Identities = 63/228 (27%), Positives = 86/228 (37%), Gaps = 41/228 (17%)
Query: 408 GPFGTCIPCNCQGGGACDPDT---GDCYSGDENPDIECADCPIGFYNDPHDP------RS 458
G C P G P G C C C F + P P +
Sbjct: 269 GHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNA 328
Query: 459 CKPCPCHNGFSCSVMPETEEV--------VCNNCPPGVTGARCELCADGYFGDPFGEHGP 510
C+ C C++ S T + VC +C G C+ C ++ DP
Sbjct: 329 CRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISD 388
Query: 511 VRPCQPCQCNNNVDPSASGN---------CDRLTGRCLKCIHNTAGIYCDQCKAGYFG-- 559
C PC+C + D + SG + G+CL C N G CDQCK ++G
Sbjct: 389 PYACIPCEC--DPDGTISGGICVSHSDPALGSVAGQCL-CKENVEGAKCDQCKPNHYGLS 445
Query: 560 --DPLAPNPADKCRACNCNPMGSEP-VGCRSD-GTCVCKPGFGGPNCE 603
DPL C+ C+CNP+GS P + C D G C+C G +CE
Sbjct: 446 ATDPLG------CQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCE 487
Score = 69.3 bits (168), Expect = 2e-11
Identities = 42/129 (32%), Positives = 55/129 (42%), Gaps = 8/129 (6%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA-----CDPDTGDCYSGD 435
QC+C +G C C + SA P G C PC+C G+ CD DTG C
Sbjct: 422 QCLCKENVEGAKCDQCKPNHYGLSAT-DPLG-CQPCDCNPLGSLPFLTCDVDTGQCLCLS 479
Query: 436 ENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCEL 495
C +C +G++ + C PC C G + S + + C C P VTG C
Sbjct: 480 YVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQC-ECRPHVTGRSCSE 538
Query: 496 CADGYFGDP 504
A GYF P
Sbjct: 539 PAPGYFFAP 547
Score = 68.9 bits (167), Expect = 2e-11
Identities = 59/231 (25%), Positives = 80/231 (34%), Gaps = 80/231 (34%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR-CLPCNC 86
C CN + C +TG+ C NC T G +CE+C +G+Y + + C PC C
Sbjct: 863 CPCNRFAELC------DPETGS---CFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLC 913
Query: 87 ----NSKGSLSARC-----DNSGRCSCKPGVTGARCDRCLPGFH--------MLTDAGCT 129
+S + C + C+C G TG +C C GF+ C
Sbjct: 914 PDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACN 973
Query: 130 QDQRLLD---------------------------------------SKCDCDPAGI---- 146
+ + D +C C +G+
Sbjct: 974 NNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPME 1033
Query: 147 ------AGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
A CD G C C P VTG CDRC GY+NL G GC C C
Sbjct: 1034 CPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPG--RGCQSCDC 1082
Score = 62.4 bits (150), Expect = 2e-09
Identities = 42/135 (31%), Positives = 56/135 (41%), Gaps = 18/135 (13%)
Query: 370 PVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNC----QGGGACD 425
PV+GA C C G C CA GY L P C C+C CD
Sbjct: 1045 PVTGA-------CPCLPNVTGLACDRCADGY----WNLVPGRGCQSCDCDPRTSQSSHCD 1093
Query: 426 PDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCP 485
TG C C++C +Y DP P C PC C+ + + + + +C C
Sbjct: 1094 QLTGQCPCKLGYGGKRCSECQENYYGDP--PGRCIPCDCNRAGTQKPICDPDTGMC-RCR 1150
Query: 486 PGVTGARCELCADGY 500
GV+G RC+ CA G+
Sbjct: 1151 EGVSGQRCDRCARGH 1165
Score = 57.8 bits (138), Expect = 6e-08
Identities = 43/149 (28%), Positives = 59/149 (39%), Gaps = 29/149 (19%)
Query: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCD-NSGRC-SCKPGVTGARC 113
C+ G C++C G++ C PC CN L CD +G C +C TG C
Sbjct: 838 CHGEVSGRRCDRCLAGYFGF---PSCHPCPCNRFAEL---CDPETGSCFNCGGFTTGRNC 891
Query: 114 DRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAG---IAGPCDAGR------CVCKPAVTGE 164
+RC+ G++ +G Q C DP+ A C C C TG
Sbjct: 892 ERCIDGYYGNPSSG----QPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGT 947
Query: 165 RCDRCRSGYYNLDGGNPE----GCTQCFC 189
+C C +G+Y GNP C C C
Sbjct: 948 QCGECSTGFY----GNPRISGAPCQPCAC 972
Score = 55.5 bits (132), Expect = 3e-07
Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 9/86 (10%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
QC C +GY G+ C +C Y D P G CIPC+C G CDPDTG C +
Sbjct: 1098 QCPCKLGYGGKRCSECQENYYGD-----PPGRCIPCDCNRAGTQKPICDPDTGMCRCREG 1152
Query: 437 NPDIECADCPIGFYNDPHDPRSCKPC 462
C C G + C C
Sbjct: 1153 VSGQRCDRCARGHSQEFPTCLQCHLC 1178
Score = 54.7 bits (130), Expect = 5e-07
Identities = 32/95 (33%), Positives = 45/95 (47%), Gaps = 8/95 (8%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYR-HRERDRCLPCNC 86
CDCN ++ TG +CL C G HCE+C G++ C PC+C
Sbjct: 455 CDCNPLGSLPFLTCDV--DTG---QCL-CLSYVTGAHCEECTVGYWGLGNHLHGCSPCDC 508
Query: 87 NSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGF 120
+ G+ S C +G+C C+P VTG C PG+
Sbjct: 509 DIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGY 543
Score = 49.3 bits (116), Expect = 2e-05
Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 10/99 (10%)
Query: 519 CNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPM 578
C + S +C RL G+C +C G CD+C G + C C+C+P
Sbjct: 769 CKCHPQGSVGSSCSRLGGQC-QCKPLVVGRCCDRCSTGSYD-----LGHHGCHPCHCHPQ 822
Query: 579 GSEPVGC-RSDGTCVCKPGFGGPNCEH---GAFSCPACY 613
GS+ C + G C C G C+ G F P+C+
Sbjct: 823 GSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCH 861
Score = 34.3 bits (77), Expect = 0.67
Identities = 14/49 (28%), Positives = 21/49 (42%), Gaps = 5/49 (10%)
Query: 153 GRCVCKPAVTGERCDRCRSGYYNLDGG-----NPEGCTQCFCYGHSASC 196
G+CVC+ G C+RC+ + + C C C HS+ C
Sbjct: 293 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRC 341
Score = 32.3 bits (72), Expect = 2.6
Identities = 19/55 (34%), Positives = 22/55 (40%), Gaps = 9/55 (16%)
Query: 568 DKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH--------GAFSCPACY 613
D AC C+P GS C R G C CKP G C+ G C C+
Sbjct: 764 DGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCH 818
Score = 30.4 bits (67), Expect = 9.7
Identities = 14/41 (34%), Positives = 19/41 (46%), Gaps = 6/41 (14%)
Query: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCN 417
P C C G GQ C CA G+ ++ F TC+ C+
Sbjct: 1142 PDTGMCRCREGVSGQRCDRCARGHSQE------FPTCLQCH 1176
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 135 bits (340), Expect = 2e-31
Identities = 158/731 (21%), Positives = 288/731 (39%), Gaps = 84/731 (11%)
Query: 389 KGQFCQDCASGY---KRDSARLGPFGTCIPCNCQGGGA-----CDPDTGDCYSGDENPDI 440
+G+ C+ C Y +R A + TCI C C GA CDP TG C +
Sbjct: 351 EGKNCERCQLHYFRNRRPGASIQE--TCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGE 408
Query: 441 ECADCPIGFYNDPH-DPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADG 499
C C GF + +P+ C C C+ S MP EE C P V G +C+ CA
Sbjct: 409 RCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPY 468
Query: 500 YFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFG 559
++ G+ C+PC C+ + S S C++ TG+C C G+ C
Sbjct: 469 HWKLASGQ-----GCEPCACDPH--NSLSPQCNQFTGQC-PCREGFGGLMCSAAAIRQCP 520
Query: 560 DPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH----------GAFS 608
D + A CRAC+C+ G+E GC ++ G C+C+PG GP C+ +
Sbjct: 521 DRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA 580
Query: 609 CPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQ 668
C C+ + + + R+ + G G + D L R+ A+ ++ I A
Sbjct: 581 CHPCFQTYDADLREQALRFGRLRNATASLWSGPG-LEDRGLASRILDAKSKIEQI--RAV 637
Query: 669 ISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTV---ERVRALGSQYQNRVRDTHRLITQ 725
+S A ++A+V S S + L L++ + E +L ++ R + L+T
Sbjct: 638 LSSPAVTE--QEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTM 695
Query: 726 MQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDY 785
Q + E I ++D P+G + A + + S+ +L + D
Sbjct: 696 YQRKREQFE------KISSAD----PSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDS 745
Query: 786 SKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAE------- 838
++A LVR+A G G G+GSP ++ + L +L + Q
Sbjct: 746 RREAERLVRQA---GGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCP 802
Query: 839 ---IEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRT 895
D R + R G + QV E R ++ + R +
Sbjct: 803 GELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR------GFNAQLQRTRQMIRAA 856
Query: 896 QKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNL 955
+++ + AQ+L + R + ++ + R L + ++ L+ + ++ + + +
Sbjct: 857 EESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAV 916
Query: 956 REFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEAL 1015
L D+ A + M + I+ ++ + Q ++ + A A+ A
Sbjct: 917 LALWLPTDS--ATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAH 974
Query: 1016 EISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQ 1075
+ ++E +G+L G +A+++ +++ R + +R + VQ
Sbjct: 975 AVEGQVEDVVGNLR-------QGTVALQEAQDTMQGTSRSLRLIQDR--------VAEVQ 1019
Query: 1076 MVITEAQKVDT 1086
V+ A+K+ T
Sbjct: 1020 QVLRPAEKLVT 1030
Score = 124 bits (312), Expect = 4e-28
Identities = 71/183 (38%), Positives = 99/183 (54%), Gaps = 26/183 (14%)
Query: 28 CDCNGKSRQCIFDRELHR--QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRE-----RDR 80
CDCNG S C FD + Q G C NC D+T+G +CE+C+ ++R+R ++
Sbjct: 316 CDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET 375
Query: 81 CLPCNCNSKGSL-SARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLL 135
C+ C C+ G++ A CD +G+C CK V G RCD C PGF LT A GC
Sbjct: 376 CISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC------- 428
Query: 136 DSKCDCDPAGIAG--PCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYG 191
+CDC+ G PCD +GRC+C P V G +CD+C ++ L G +GC C C
Sbjct: 429 -HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASG--QGCEPCACDP 485
Query: 192 HSA 194
H++
Sbjct: 486 HNS 488
Score = 91.3 bits (225), Expect = 5e-18
Identities = 52/159 (32%), Positives = 71/159 (44%), Gaps = 31/159 (19%)
Query: 56 CNDNTDGIHCEKCKNGFYRHR--------ERDRCLPCNCN---------------SKGSL 92
C NT G +CE+C FY +R + C C+CN S+G+
Sbjct: 281 CQHNTAGPNCERCAP-FYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAY 339
Query: 93 SARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCD- 151
CDN C+ G C+RC + G + + + +CD D A PCD
Sbjct: 340 GGVCDN-----CRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDP 394
Query: 152 -AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
G+CVCK V GERCD C+ G+ L NP+GC +C C
Sbjct: 395 VTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDC 433
Score = 89.4 bits (220), Expect = 2e-17
Identities = 56/159 (35%), Positives = 74/159 (46%), Gaps = 27/159 (16%)
Query: 28 CDCN--GKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCN 85
CDCN G R D E RCL C N G C++C ++ C PC
Sbjct: 431 CDCNILGSRRDMPCDEE-------SGRCL-CLPNVVGPKCDQCAPYHWKLASGQGCEPCA 482
Query: 86 CNSKGSLSARCDN-SGRCSCKPGVTGARCD-----RCLPGFHMLTDAGCTQDQRLLDSKC 139
C+ SLS +C+ +G+C C+ G G C +C + GC C
Sbjct: 483 CDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA--------C 534
Query: 140 DCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYYN 175
DCD G GP CD +GRC+C+P +TG RCD+C+ GY N
Sbjct: 535 DCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCN 573
Score = 77.8 bits (190), Expect = 5e-14
Identities = 71/247 (28%), Positives = 93/247 (37%), Gaps = 42/247 (17%)
Query: 416 CNCQGGGACDPDTGD-----CYSGDENPDIECADCPIGFYNDP------HDPRSCKPCPC 464
C + G + P T C C C + N P D C+ C C
Sbjct: 259 CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDC 318
Query: 465 HNGFS--CSVMPETEEV-------VCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQ 515
NG S C P VC+NC G CE C YF + C
Sbjct: 319 -NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCI 377
Query: 516 PCQCN-NNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACN 574
C+C+ + P A CD +TG+C+ C + G CD CK G+ G A NP C C+
Sbjct: 378 SCECDPDGAVPGAP--CDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYA-NP-QGCHRCD 432
Query: 575 CNPMGS-EPVGC-RSDGTCVCKPGFGGPNCEHGA---------FSCPAC----YNQVKIQ 619
CN +GS + C G C+C P GP C+ A C C +N + Q
Sbjct: 433 CNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQ 492
Query: 620 MDQFMQQ 626
+QF Q
Sbjct: 493 CNQFTGQ 499
Score = 44.3 bits (103), Expect = 7e-04
Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 9/68 (13%)
Query: 138 KCDCDPAGIAGPCDAGR----CVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCF 188
+C P AGP A + CVC+ G C+RC Y N +G + C +C
Sbjct: 258 RCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCD 317
Query: 189 CYGHSASC 196
C GHS +C
Sbjct: 318 CNGHSETC 325
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 135 bits (340), Expect = 2e-31
Identities = 158/731 (21%), Positives = 288/731 (39%), Gaps = 84/731 (11%)
Query: 389 KGQFCQDCASGY---KRDSARLGPFGTCIPCNCQGGGA-----CDPDTGDCYSGDENPDI 440
+G+ C+ C Y +R A + TCI C C GA CDP TG C +
Sbjct: 351 EGKNCERCQLHYFRNRRPGASIQE--TCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGE 408
Query: 441 ECADCPIGFYNDPH-DPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADG 499
C C GF + +P+ C C C+ S MP EE C P V G +C+ CA
Sbjct: 409 RCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPY 468
Query: 500 YFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFG 559
++ G+ C+PC C+ + S S C++ TG+C C G+ C
Sbjct: 469 HWKLASGQ-----GCEPCACDPH--NSLSPQCNQFTGQC-PCREGFGGLMCSAAAIRQCP 520
Query: 560 DPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH----------GAFS 608
D + A CRAC+C+ G+E GC ++ G C+C+PG GP C+ +
Sbjct: 521 DRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA 580
Query: 609 CPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQ 668
C C+ + + + R+ + G G + D L R+ A+ ++ I A
Sbjct: 581 CHPCFQTYDADLREQALRFGRLRNATASLWSGPG-LEDRGLASRILDAKSKIEQI--RAV 637
Query: 669 ISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTV---ERVRALGSQYQNRVRDTHRLITQ 725
+S A ++A+V S S + L L++ + E +L ++ R + L+T
Sbjct: 638 LSSPAVTE--QEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTM 695
Query: 726 MQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDY 785
Q + E I ++D P+G + A + + S+ +L + D
Sbjct: 696 YQRKREQFE------KISSAD----PSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDS 745
Query: 786 SKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAE------- 838
++A LVR+A G G G+GSP ++ + L +L + Q
Sbjct: 746 RREAERLVRQA---GGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCP 802
Query: 839 ---IEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRT 895
D R + R G + QV E R ++ + R +
Sbjct: 803 GELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR------GFNAQLQRTRQMIRAA 856
Query: 896 QKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNL 955
+++ + AQ+L + R + ++ + R L + ++ L+ + ++ + + +
Sbjct: 857 EESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAV 916
Query: 956 REFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEAL 1015
L D+ A + M + I+ ++ + Q ++ + A A+ A
Sbjct: 917 LALWLPTDS--ATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAH 974
Query: 1016 EISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQ 1075
+ ++E +G+L G +A+++ +++ R + +R + VQ
Sbjct: 975 AVEGQVEDVVGNLR-------QGTVALQEAQDTMQGTSRSLRLIQDR--------VAEVQ 1019
Query: 1076 MVITEAQKVDT 1086
V+ A+K+ T
Sbjct: 1020 QVLRPAEKLVT 1030
Score = 124 bits (312), Expect = 4e-28
Identities = 71/183 (38%), Positives = 99/183 (54%), Gaps = 26/183 (14%)
Query: 28 CDCNGKSRQCIFDRELHR--QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRE-----RDR 80
CDCNG S C FD + Q G C NC D+T+G +CE+C+ ++R+R ++
Sbjct: 316 CDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET 375
Query: 81 CLPCNCNSKGSL-SARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLL 135
C+ C C+ G++ A CD +G+C CK V G RCD C PGF LT A GC
Sbjct: 376 CISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC------- 428
Query: 136 DSKCDCDPAGIAG--PCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYG 191
+CDC+ G PCD +GRC+C P V G +CD+C ++ L G +GC C C
Sbjct: 429 -HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASG--QGCEPCACDP 485
Query: 192 HSA 194
H++
Sbjct: 486 HNS 488
Score = 91.3 bits (225), Expect = 5e-18
Identities = 52/159 (32%), Positives = 71/159 (44%), Gaps = 31/159 (19%)
Query: 56 CNDNTDGIHCEKCKNGFYRHR--------ERDRCLPCNCN---------------SKGSL 92
C NT G +CE+C FY +R + C C+CN S+G+
Sbjct: 281 CQHNTAGPNCERCAP-FYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAY 339
Query: 93 SARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCD- 151
CDN C+ G C+RC + G + + + +CD D A PCD
Sbjct: 340 GGVCDN-----CRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDP 394
Query: 152 -AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
G+CVCK V GERCD C+ G+ L NP+GC +C C
Sbjct: 395 VTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDC 433
Score = 89.4 bits (220), Expect = 2e-17
Identities = 56/159 (35%), Positives = 74/159 (46%), Gaps = 27/159 (16%)
Query: 28 CDCN--GKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCN 85
CDCN G R D E RCL C N G C++C ++ C PC
Sbjct: 431 CDCNILGSRRDMPCDEE-------SGRCL-CLPNVVGPKCDQCAPYHWKLASGQGCEPCA 482
Query: 86 CNSKGSLSARCDN-SGRCSCKPGVTGARCD-----RCLPGFHMLTDAGCTQDQRLLDSKC 139
C+ SLS +C+ +G+C C+ G G C +C + GC C
Sbjct: 483 CDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA--------C 534
Query: 140 DCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYYN 175
DCD G GP CD +GRC+C+P +TG RCD+C+ GY N
Sbjct: 535 DCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCN 573
Score = 77.8 bits (190), Expect = 5e-14
Identities = 71/247 (28%), Positives = 93/247 (37%), Gaps = 42/247 (17%)
Query: 416 CNCQGGGACDPDTGD-----CYSGDENPDIECADCPIGFYNDP------HDPRSCKPCPC 464
C + G + P T C C C + N P D C+ C C
Sbjct: 259 CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDC 318
Query: 465 HNGFS--CSVMPETEEV-------VCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQ 515
NG S C P VC+NC G CE C YF + C
Sbjct: 319 -NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCI 377
Query: 516 PCQCN-NNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACN 574
C+C+ + P A CD +TG+C+ C + G CD CK G+ G A NP C C+
Sbjct: 378 SCECDPDGAVPGAP--CDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYA-NP-QGCHRCD 432
Query: 575 CNPMGS-EPVGC-RSDGTCVCKPGFGGPNCEHGA---------FSCPAC----YNQVKIQ 619
CN +GS + C G C+C P GP C+ A C C +N + Q
Sbjct: 433 CNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQ 492
Query: 620 MDQFMQQ 626
+QF Q
Sbjct: 493 CNQFTGQ 499
Score = 44.3 bits (103), Expect = 7e-04
Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 9/68 (13%)
Query: 138 KCDCDPAGIAGPCDAGR----CVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCF 188
+C P AGP A + CVC+ G C+RC Y N +G + C +C
Sbjct: 258 RCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCD 317
Query: 189 CYGHSASC 196
C GHS +C
Sbjct: 318 CNGHSETC 325
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 135 bits (340), Expect = 2e-31
Identities = 158/731 (21%), Positives = 288/731 (39%), Gaps = 84/731 (11%)
Query: 389 KGQFCQDCASGY---KRDSARLGPFGTCIPCNCQGGGA-----CDPDTGDCYSGDENPDI 440
+G+ C+ C Y +R A + TCI C C GA CDP TG C +
Sbjct: 351 EGKNCERCQLHYFRNRRPGASIQE--TCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGE 408
Query: 441 ECADCPIGFYNDPH-DPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADG 499
C C GF + +P+ C C C+ S MP EE C P V G +C+ CA
Sbjct: 409 RCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPY 468
Query: 500 YFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFG 559
++ G+ C+PC C+ + S S C++ TG+C C G+ C
Sbjct: 469 HWKLASGQ-----GCEPCACDPH--NSLSPQCNQFTGQC-PCREGFGGLMCSAAAIRQCP 520
Query: 560 DPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH----------GAFS 608
D + A CRAC+C+ G+E GC ++ G C+C+PG GP C+ +
Sbjct: 521 DRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA 580
Query: 609 CPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQ 668
C C+ + + + R+ + G G + D L R+ A+ ++ I A
Sbjct: 581 CHPCFQTYDADLREQALRFGRLRNATASLWSGPG-LEDRGLASRILDAKSKIEQI--RAV 637
Query: 669 ISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTV---ERVRALGSQYQNRVRDTHRLITQ 725
+S A ++A+V S S + L L++ + E +L ++ R + L+T
Sbjct: 638 LSSPAVTE--QEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTM 695
Query: 726 MQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDY 785
Q + E I ++D P+G + A + + S+ +L + D
Sbjct: 696 YQRKREQFE------KISSAD----PSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDS 745
Query: 786 SKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAE------- 838
++A LVR+A G G G+GSP ++ + L +L + Q
Sbjct: 746 RREAERLVRQA---GGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCP 802
Query: 839 ---IEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRT 895
D R + R G + QV E R ++ + R +
Sbjct: 803 GELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR------GFNAQLQRTRQMIRAA 856
Query: 896 QKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNL 955
+++ + AQ+L + R + ++ + R L + ++ L+ + ++ + + +
Sbjct: 857 EESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAV 916
Query: 956 REFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEAL 1015
L D+ A + M + I+ ++ + Q ++ + A A+ A
Sbjct: 917 LALWLPTDS--ATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAH 974
Query: 1016 EISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQ 1075
+ ++E +G+L G +A+++ +++ R + +R + VQ
Sbjct: 975 AVEGQVEDVVGNLR-------QGTVALQEAQDTMQGTSRSLRLIQDR--------VAEVQ 1019
Query: 1076 MVITEAQKVDT 1086
V+ A+K+ T
Sbjct: 1020 QVLRPAEKLVT 1030
Score = 124 bits (312), Expect = 4e-28
Identities = 71/183 (38%), Positives = 99/183 (54%), Gaps = 26/183 (14%)
Query: 28 CDCNGKSRQCIFDRELHR--QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRE-----RDR 80
CDCNG S C FD + Q G C NC D+T+G +CE+C+ ++R+R ++
Sbjct: 316 CDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET 375
Query: 81 CLPCNCNSKGSL-SARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLL 135
C+ C C+ G++ A CD +G+C CK V G RCD C PGF LT A GC
Sbjct: 376 CISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC------- 428
Query: 136 DSKCDCDPAGIAG--PCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYG 191
+CDC+ G PCD +GRC+C P V G +CD+C ++ L G +GC C C
Sbjct: 429 -HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASG--QGCEPCACDP 485
Query: 192 HSA 194
H++
Sbjct: 486 HNS 488
Score = 91.3 bits (225), Expect = 5e-18
Identities = 52/159 (32%), Positives = 71/159 (44%), Gaps = 31/159 (19%)
Query: 56 CNDNTDGIHCEKCKNGFYRHR--------ERDRCLPCNCN---------------SKGSL 92
C NT G +CE+C FY +R + C C+CN S+G+
Sbjct: 281 CQHNTAGPNCERCAP-FYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAY 339
Query: 93 SARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCD- 151
CDN C+ G C+RC + G + + + +CD D A PCD
Sbjct: 340 GGVCDN-----CRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDP 394
Query: 152 -AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
G+CVCK V GERCD C+ G+ L NP+GC +C C
Sbjct: 395 VTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDC 433
Score = 89.4 bits (220), Expect = 2e-17
Identities = 56/159 (35%), Positives = 74/159 (46%), Gaps = 27/159 (16%)
Query: 28 CDCN--GKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCN 85
CDCN G R D E RCL C N G C++C ++ C PC
Sbjct: 431 CDCNILGSRRDMPCDEE-------SGRCL-CLPNVVGPKCDQCAPYHWKLASGQGCEPCA 482
Query: 86 CNSKGSLSARCDN-SGRCSCKPGVTGARCD-----RCLPGFHMLTDAGCTQDQRLLDSKC 139
C+ SLS +C+ +G+C C+ G G C +C + GC C
Sbjct: 483 CDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA--------C 534
Query: 140 DCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYYN 175
DCD G GP CD +GRC+C+P +TG RCD+C+ GY N
Sbjct: 535 DCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCN 573
Score = 77.8 bits (190), Expect = 5e-14
Identities = 71/247 (28%), Positives = 93/247 (37%), Gaps = 42/247 (17%)
Query: 416 CNCQGGGACDPDTGD-----CYSGDENPDIECADCPIGFYNDP------HDPRSCKPCPC 464
C + G + P T C C C + N P D C+ C C
Sbjct: 259 CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDC 318
Query: 465 HNGFS--CSVMPETEEV-------VCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQ 515
NG S C P VC+NC G CE C YF + C
Sbjct: 319 -NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCI 377
Query: 516 PCQCN-NNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACN 574
C+C+ + P A CD +TG+C+ C + G CD CK G+ G A NP C C+
Sbjct: 378 SCECDPDGAVPGAP--CDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYA-NP-QGCHRCD 432
Query: 575 CNPMGS-EPVGC-RSDGTCVCKPGFGGPNCEHGA---------FSCPAC----YNQVKIQ 619
CN +GS + C G C+C P GP C+ A C C +N + Q
Sbjct: 433 CNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQ 492
Query: 620 MDQFMQQ 626
+QF Q
Sbjct: 493 CNQFTGQ 499
Score = 44.3 bits (103), Expect = 7e-04
Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 9/68 (13%)
Query: 138 KCDCDPAGIAGPCDAGR----CVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCF 188
+C P AGP A + CVC+ G C+RC Y N +G + C +C
Sbjct: 258 RCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCD 317
Query: 189 CYGHSASC 196
C GHS +C
Sbjct: 318 CNGHSETC 325
>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
Length = 1823
Score = 132 bits (332), Expect = 2e-30
Identities = 153/648 (23%), Positives = 263/648 (40%), Gaps = 97/648 (14%)
Query: 411 GTCIPCNCQGGG-ACDPDTGDCYSGDENPDIE-CADCPIGFYNDP--HDPRSCKPCPCH- 465
G C+PC+C G C +G C N E C C G+ D P+ C+PCPC
Sbjct: 77 GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136
Query: 466 ---NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN 522
F+ S + V C C G CE CA GY+G+P C+ C C+ N
Sbjct: 137 PHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLIGST---CKKCDCSGN 192
Query: 523 VDPSAS-GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581
DP+ +CD +TG+C C+ NT G C++C GY+GD A C CNC G
Sbjct: 193 SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGD---ARIAKNCAVCNC---GGG 246
Query: 582 PVGCRS-DGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFMQQLQ---RMEALISKA 637
P C S G C+ + GF P CP I D+ + L R+ AL S
Sbjct: 247 P--CDSVTGECL-EEGFEPPT----GMDCPT------ISCDKCVWDLTDALRLAAL-SIE 292
Query: 638 QGGDGVVPDTELEGRMQQAEQALQDI-LRDAQISEGASRSLGLQLAKVRSQENSYQSRLD 696
+G GV+ + + + I L ++SE L+ ++ + EN+ +S L
Sbjct: 293 EGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSE-RENQYALRKIQINNAENTMKSLLS 351
Query: 697 DLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKS 756
D++ VE+ E++AS
Sbjct: 352 DVEELVEK---------------------------ENQAS-------------------- 364
Query: 757 LAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGL 816
++ + + +++ ++ QL + D + + K L+ G + + L
Sbjct: 365 --RKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVL 422
Query: 817 VEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQV--EEAKRI 874
+K+ + Q + + EAD +Y+ L +S RL + F V E+
Sbjct: 423 AQKMLEEIRSRQPFFTQRELVDEEADEAYE-LLSQAESWQRLHNETRTLFPVVLEQLDDY 481
Query: 875 KQKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRA 934
K L + + ++ + R +++ N A+Q ++ + +E+ + + N++ S +
Sbjct: 482 NAKLSDLQEALDQALN-YVRDAEDM-NRATAARQ--RDHEKQQERVREQMEVVNMSLSTS 537
Query: 935 QEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQK-VSDASDKTQQA 993
++L+ T E++ I+KN ++D K+E + + LS +S V +A D Q
Sbjct: 538 ADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDL 597
Query: 994 ERALGSAAADAQRA-KNGAGEALEISSEIEQEIGSLNLEANVTADGAL 1040
++ + + NG + +S + + I + EAN TA+ AL
Sbjct: 598 QQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFAL 645
Score = 95.9 bits (237), Expect = 2e-19
Identities = 62/182 (34%), Positives = 82/182 (45%), Gaps = 36/182 (19%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR---CLPC 84
CDCNG S +C+ G+G+ C++C NT G HCEKC +G+ R C PC
Sbjct: 82 CDCNGNSNECL--------DGSGY-CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPC 132
Query: 85 NC-----NSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH---MLTDAGCTQDQRLLD 136
C + R + + RC C G C+RC PG++ +L + C
Sbjct: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC-------- 184
Query: 137 SKCDC----DPAGIAGPCD--AGRC-VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
KCDC DP I CD G+C C TG +C+RC GYY D + C C C
Sbjct: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNC 243
Query: 190 YG 191
G
Sbjct: 244 GG 245
Score = 73.9 bits (180), Expect = 8e-13
Identities = 49/140 (35%), Positives = 63/140 (45%), Gaps = 23/140 (16%)
Query: 66 EKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRC-SCKPGVTGARCDRCLPGFHMLT 124
EKC GF+ H C+PC+CN G+ + D SG C C+ TG C++CL G+ +
Sbjct: 65 EKCNAGFF-HTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
Query: 125 DAGCTQDQRLLDSKCDC---DPAGIAGPC----DAGRCVCKPAVTGERCDRCRSGYYNLD 177
G Q C C A A C A RC+C G C+RC GYY
Sbjct: 122 IRGAPQ----FCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY--- 174
Query: 178 GGNP----EGCTQCFCYGHS 193
GNP C +C C G+S
Sbjct: 175 -GNPLLIGSTCKKCDCSGNS 193
Score = 58.9 bits (141), Expect = 3e-08
Identities = 41/145 (28%), Positives = 52/145 (35%), Gaps = 30/145 (20%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG-------ACDPDTGDCYS 433
+CIC Y G C+ CA GY + +G TC C+C G CD TG C +
Sbjct: 154 RCICNENYAGPNCERCAPGYYGNPLLIG--STCKKCDCSGNSDPNLIFEDCDEVTGQCRN 211
Query: 434 GDEN-PDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGAR 492
N +C C G+Y D ++C C C G SV E
Sbjct: 212 CLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGE----------------- 254
Query: 493 CELCADGYFGDPFGEHGPVRPCQPC 517
C + F P G P C C
Sbjct: 255 ---CLEEGFEPPTGMDCPTISCDKC 276
Score = 31.2 bits (69), Expect = 5.7
Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 7/65 (10%)
Query: 167 DRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQD----VDGWKAVQ 222
++C +G+++ G C C C G+S C + Y VH +T + +DG+
Sbjct: 65 EKCNAGFFHTLSGE---CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
Query: 223 RNGSP 227
G+P
Sbjct: 122 IRGAP 126
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 129 bits (325), Expect = 1e-29
Identities = 150/645 (23%), Positives = 259/645 (40%), Gaps = 98/645 (15%)
Query: 411 GTCIPCNCQGGG-ACDPDTGDCYSGDENPDIE-CADCPIGFYNDP--HDPRSCKPCPCH- 465
G C+PC+C G C +G C N E C C G+ D P+ C+PCPC
Sbjct: 77 GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136
Query: 466 ---NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN 522
F+ S + V C C G CE CA GY+G+P C+ C C+ N
Sbjct: 137 PHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLIGST---CKKCDCSGN 192
Query: 523 VDPSAS-GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581
DP+ +CD +TG+C C+ NT G C++C GY+GD A C CNC G
Sbjct: 193 SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGD---ARIAKNCAVCNC---GGG 246
Query: 582 PVGCRS-DGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGG 640
P C S G C+ + GF P C C + R+ AL S +G
Sbjct: 247 P--CDSVTGECL-EEGFEPPT------GCDKCVWD--------LTDALRLAAL-SIEEGK 288
Query: 641 DGVVPDTELEGRMQQAEQALQDI-LRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLK 699
GV+ + + + I L ++SE L+ ++ + EN+ +S L D++
Sbjct: 289 SGVLSVSSGAAAHRHVNEINATIYLLKTKLSE-RENQYALRKIQINNAENTMKSLLSDVE 347
Query: 700 MTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQ 759
VE+ E++AS +
Sbjct: 348 ELVEK---------------------------ENQAS----------------------R 358
Query: 760 EATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEK 819
+ + + +++ ++ QL + D + + K L+ G + + L +K
Sbjct: 359 KGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQK 418
Query: 820 LEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQV--EEAKRIKQK 877
+ + Q + + EAD +Y+ L +S RL + F V E+ K
Sbjct: 419 MLEEIRSRQPFFTQRELVDEEADEAYE-LLSQAESWQRLHNETRTLFPVVLEQLDDYNAK 477
Query: 878 ADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEA 937
L + + ++ + R +++ N A+Q ++ + +E+ + + N++ S + ++
Sbjct: 478 LSDLQEALDQALN-YVRDAEDM-NRATAARQ--RDHEKQQERVREQMEVVNMSLSTSADS 533
Query: 938 LSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQK-VSDASDKTQQAERA 996
L+ T E++ I+KN ++D K+E + + LS +S V +A D Q ++
Sbjct: 534 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 593
Query: 997 LGSAAADAQRA-KNGAGEALEISSEIEQEIGSLNLEANVTADGAL 1040
+ + NG + +S + + I + EAN TA+ AL
Sbjct: 594 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFAL 638
Score = 95.9 bits (237), Expect = 2e-19
Identities = 62/182 (34%), Positives = 82/182 (45%), Gaps = 36/182 (19%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR---CLPC 84
CDCNG S +C+ G+G+ C++C NT G HCEKC +G+ R C PC
Sbjct: 82 CDCNGNSNECL--------DGSGY-CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPC 132
Query: 85 NC-----NSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH---MLTDAGCTQDQRLLD 136
C + R + + RC C G C+RC PG++ +L + C
Sbjct: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC-------- 184
Query: 137 SKCDC----DPAGIAGPCD--AGRC-VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
KCDC DP I CD G+C C TG +C+RC GYY D + C C C
Sbjct: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNC 243
Query: 190 YG 191
G
Sbjct: 244 GG 245
Score = 73.9 bits (180), Expect = 8e-13
Identities = 49/140 (35%), Positives = 63/140 (45%), Gaps = 23/140 (16%)
Query: 66 EKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRC-SCKPGVTGARCDRCLPGFHMLT 124
EKC GF+ H C+PC+CN G+ + D SG C C+ TG C++CL G+ +
Sbjct: 65 EKCNAGFF-HTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
Query: 125 DAGCTQDQRLLDSKCDC---DPAGIAGPC----DAGRCVCKPAVTGERCDRCRSGYYNLD 177
G Q C C A A C A RC+C G C+RC GYY
Sbjct: 122 IRGAPQ----FCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY--- 174
Query: 178 GGNP----EGCTQCFCYGHS 193
GNP C +C C G+S
Sbjct: 175 -GNPLLIGSTCKKCDCSGNS 193
Score = 58.9 bits (141), Expect = 3e-08
Identities = 39/125 (31%), Positives = 51/125 (40%), Gaps = 16/125 (12%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG-------ACDPDTGDCYS 433
+CIC Y G C+ CA GY + +G TC C+C G CD TG C +
Sbjct: 154 RCICNENYAGPNCERCAPGYYGNPLLIG--STCKKCDCSGNSDPNLIFEDCDEVTGQCRN 211
Query: 434 GDEN-PDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEE------VVCNNCPP 486
N +C C G+Y D ++C C C G SV E E C+ C
Sbjct: 212 CLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVW 271
Query: 487 GVTGA 491
+T A
Sbjct: 272 DLTDA 276
Score = 31.2 bits (69), Expect = 5.7
Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 7/65 (10%)
Query: 167 DRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQD----VDGWKAVQ 222
++C +G+++ G C C C G+S C + Y VH +T + +DG+
Sbjct: 65 EKCNAGFFHTLSGE---CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
Query: 223 RNGSP 227
G+P
Sbjct: 122 IRGAP 126
>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 129 bits (325), Expect = 1e-29
Identities = 150/645 (23%), Positives = 259/645 (40%), Gaps = 98/645 (15%)
Query: 411 GTCIPCNCQGGG-ACDPDTGDCYSGDENPDIE-CADCPIGFYNDP--HDPRSCKPCPCH- 465
G C+PC+C G C +G C N E C C G+ D P+ C+PCPC
Sbjct: 77 GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136
Query: 466 ---NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN 522
F+ S + V C C G CE CA GY+G+P C+ C C+ N
Sbjct: 137 PHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLIGST---CKKCDCSGN 192
Query: 523 VDPSAS-GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581
DP+ +CD +TG+C C+ NT G C++C GY+GD A C CNC G
Sbjct: 193 SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGD---ARIAKNCAVCNC---GGG 246
Query: 582 PVGCRS-DGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGG 640
P C S G C+ + GF P C C + R+ AL S +G
Sbjct: 247 P--CDSVTGECL-EEGFEPPT------GCDKCVWD--------LTDALRLAAL-SIEEGK 288
Query: 641 DGVVPDTELEGRMQQAEQALQDI-LRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLK 699
GV+ + + + I L ++SE L+ ++ + EN+ +S L D++
Sbjct: 289 SGVLSVSSGAAAHRHVNEINATIYLLKTKLSE-RENQYALRKIQINNAENTMKSLLSDVE 347
Query: 700 MTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQ 759
VE+ E++AS +
Sbjct: 348 ELVEK---------------------------ENQAS----------------------R 358
Query: 760 EATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEK 819
+ + + +++ ++ QL + D + + K L+ G + + L +K
Sbjct: 359 KGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQK 418
Query: 820 LEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQV--EEAKRIKQK 877
+ + Q + + EAD +Y+ L +S RL + F V E+ K
Sbjct: 419 MLEEIRSRQPFFTQRELVDEEADEAYE-LLSQAESWQRLHNETRTLFPVVLEQLDDYNAK 477
Query: 878 ADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEA 937
L + + ++ + R +++ N A+Q ++ + +E+ + + N++ S + ++
Sbjct: 478 LSDLQEALDQALN-YVRDAEDM-NRATAARQ--RDHEKQQERVREQMEVVNMSLSTSADS 533
Query: 938 LSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQK-VSDASDKTQQAERA 996
L+ T E++ I+KN ++D K+E + + LS +S V +A D Q ++
Sbjct: 534 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 593
Query: 997 LGSAAADAQRA-KNGAGEALEISSEIEQEIGSLNLEANVTADGAL 1040
+ + NG + +S + + I + EAN TA+ AL
Sbjct: 594 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFAL 638
Score = 95.9 bits (237), Expect = 2e-19
Identities = 62/182 (34%), Positives = 82/182 (45%), Gaps = 36/182 (19%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR---CLPC 84
CDCNG S +C+ G+G+ C++C NT G HCEKC +G+ R C PC
Sbjct: 82 CDCNGNSNECL--------DGSGY-CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPC 132
Query: 85 NC-----NSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH---MLTDAGCTQDQRLLD 136
C + R + + RC C G C+RC PG++ +L + C
Sbjct: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC-------- 184
Query: 137 SKCDC----DPAGIAGPCD--AGRC-VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
KCDC DP I CD G+C C TG +C+RC GYY D + C C C
Sbjct: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNC 243
Query: 190 YG 191
G
Sbjct: 244 GG 245
Score = 73.9 bits (180), Expect = 8e-13
Identities = 49/140 (35%), Positives = 63/140 (45%), Gaps = 23/140 (16%)
Query: 66 EKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRC-SCKPGVTGARCDRCLPGFHMLT 124
EKC GF+ H C+PC+CN G+ + D SG C C+ TG C++CL G+ +
Sbjct: 65 EKCNAGFF-HTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
Query: 125 DAGCTQDQRLLDSKCDC---DPAGIAGPC----DAGRCVCKPAVTGERCDRCRSGYYNLD 177
G Q C C A A C A RC+C G C+RC GYY
Sbjct: 122 IRGAPQ----FCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY--- 174
Query: 178 GGNP----EGCTQCFCYGHS 193
GNP C +C C G+S
Sbjct: 175 -GNPLLIGSTCKKCDCSGNS 193
Score = 58.9 bits (141), Expect = 3e-08
Identities = 39/125 (31%), Positives = 51/125 (40%), Gaps = 16/125 (12%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG-------ACDPDTGDCYS 433
+CIC Y G C+ CA GY + +G TC C+C G CD TG C +
Sbjct: 154 RCICNENYAGPNCERCAPGYYGNPLLIG--STCKKCDCSGNSDPNLIFEDCDEVTGQCRN 211
Query: 434 GDEN-PDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEE------VVCNNCPP 486
N +C C G+Y D ++C C C G SV E E C+ C
Sbjct: 212 CLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVW 271
Query: 487 GVTGA 491
+T A
Sbjct: 272 DLTDA 276
Score = 31.2 bits (69), Expect = 5.7
Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 7/65 (10%)
Query: 167 DRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQD----VDGWKAVQ 222
++C +G+++ G C C C G+S C + Y VH +T + +DG+
Sbjct: 65 EKCNAGFFHTLSGE---CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
Query: 223 RNGSP 227
G+P
Sbjct: 122 IRGAP 126
>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
Length = 1668
Score = 124 bits (311), Expect = 5e-28
Identities = 136/569 (23%), Positives = 223/569 (39%), Gaps = 93/569 (16%)
Query: 394 QDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPDIE-CADCPIGFY- 450
Q C+ GY RD L G C+PCNC G C +G C + N E C C G+Y
Sbjct: 57 QGCSPGYYRDHKGLYT-GRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYG 115
Query: 451 NDPHDPRSCKPCPCH--NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEH 508
N H SC+ CPC N F+ + +V C+ C G TG +CE CA GYFG+P
Sbjct: 116 NAVHG--SCRACPCPHTNSFATGCVVNGGDVRCS-CKAGYTGTQCERCAPGYFGNPQKFG 172
Query: 509 GPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPAD 568
G CQPC CN+N G+C LTG C+ +P +PA+
Sbjct: 173 G---SCQPCSCNSN---GQLGSCHPLTGDCIN------------------QEPKDSSPAE 208
Query: 569 KCRAC-NCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAF-SCPACYNQVKIQMDQFMQQ 626
+C C +C + + + K G + G Q K +Q +
Sbjct: 209 ECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNY 268
Query: 627 LQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRS 686
+ SK +G LE + Q + + AQ++ +++L + +
Sbjct: 269 RSAISNHGSKIEG---------LERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQ 319
Query: 687 QENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNI---P 743
++ ++ V + + + + + + L ++ SL E EA L +
Sbjct: 320 SAKELDVKIKNVIRNVHMLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQE 379
Query: 744 ASDHYVGPNGFKSLAQEATRLAESHVESASNMEQ----------------------LTRE 781
A+ NG + A + V+ ++++ + +
Sbjct: 380 AAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKS 439
Query: 782 TEDYSKQALSL--VRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTR------- 832
++Y K A SL R+ L + V S S A LVE+ EK Q+L +
Sbjct: 440 QKEYEKLAASLNEARQELSDKVRELSRS---AGKTSLVEEAEKHARSLQELAKQLEEIKR 496
Query: 833 -----EATQAEIEADRSYQHSLRLL----DSVSRLQGVSDQSFQVEEAKRIKQKADSLSS 883
E + ++A +Y++ L + D+ +R S+ + Q + + +KA +LSS
Sbjct: 497 NASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSS 556
Query: 884 LVTRHMDEFKRTQKNLGNWKEEAQQLLQN 912
+ ++E K TQK L K+E L N
Sbjct: 557 NSDKLLNEAKMTQKKL---KQEVSPALNN 582
Score = 98.6 bits (244), Expect = 3e-20
Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 22/158 (13%)
Query: 22 TSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRC 81
T R C+CNG S QC Q G+G C+NC NT G HCE+C+ G+Y + C
Sbjct: 72 TGRCVPCNCNGHSNQC--------QDGSGI-CVNCQHNTAGEHCERCQEGYYGNAVHGSC 122
Query: 82 LPCNCNSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSK 138
C C S + C +G RCSCK G TG +C+RC PG+ G Q
Sbjct: 123 RACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF-----GNPQKFGGSCQP 177
Query: 139 CDCDPAGIAGPCD--AGRCV---CKPAVTGERCDRCRS 171
C C+ G G C G C+ K + E CD C S
Sbjct: 178 CSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215
Score = 67.8 bits (164), Expect = 5e-11
Identities = 48/145 (33%), Positives = 62/145 (42%), Gaps = 30/145 (20%)
Query: 68 CKNGFYRHRE---RDRCLPCNCNSKGSLSARC-DNSGRC-SCKPGVTGARCDRCLPGFHM 122
C G+YR + RC+PCNCN S +C D SG C +C+ G C+RC G++
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNGH---SNQCQDGSGICVNCQHNTAGEHCERCQEGYYG 115
Query: 123 LTDAGCTQDQRLLDSKCDCDPAG-IAGPCDAG----RCVCKPAVTGERCDRCRSGYYNLD 177
G + C C A C RC CK TG +C+RC GY+
Sbjct: 116 NAVHGSCR-------ACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF--- 165
Query: 178 GGNPE----GCTQCFC--YGHSASC 196
GNP+ C C C G SC
Sbjct: 166 -GNPQKFGGSCQPCSCNSNGQLGSC 189
Score = 59.3 bits (142), Expect = 2e-08
Identities = 29/71 (40%), Positives = 38/71 (53%), Gaps = 8/71 (11%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG---GACDPDTGDCYS---G 434
+C C GY G C+ CA GY + + G G+C PC+C G+C P TGDC +
Sbjct: 145 RCSCKAGYTGTQCERCAPGYFGNPQKFG--GSCQPCSCNSNGQLGSCHPLTGDCINQEPK 202
Query: 435 DENPDIECADC 445
D +P EC DC
Sbjct: 203 DSSPAEECDDC 213
Score = 37.7 bits (86), Expect = 0.061
Identities = 49/256 (19%), Positives = 103/256 (40%), Gaps = 40/256 (15%)
Query: 856 SRLQGVSDQSFQVEEAKRIKQKADSLS-------SLVTRHMDEFKRTQKNLGNWKEEAQQ 908
S+LQG+S + +E+ + ++ +A L S ++ H + + ++ L + +E +
Sbjct: 236 SQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFET 295
Query: 909 LLQNGKSGREKSDQLLSRANLAKSRAQEA----------LSMGNA--TFYEVE------- 949
L + + K+ L + N A A+E + M N T+ +
Sbjct: 296 LQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHMLNRIRTWQKTHQGENNGL 355
Query: 950 --SILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRA 1007
SI +L E++ ++ + +A +EA + + A+ Q+ ERALG+ +
Sbjct: 356 ANSIRDSLNEYEAKLSDLRARLQEA-------AAQAKQANGLNQENERALGAIQRQVKEI 408
Query: 1008 KNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEF 1067
+ + + + + + L+ N+ +K L + + E EL K E
Sbjct: 409 NSLQSDFTKYLTTADSSL----LQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVREL 464
Query: 1068 DTNMDAVQMVITEAQK 1083
+ +V EA+K
Sbjct: 465 SRSAGKTSLV-EEAEK 479
>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
Length = 639
Score = 120 bits (302), Expect = 5e-27
Identities = 64/186 (34%), Positives = 83/186 (44%), Gaps = 18/186 (9%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA-CDPDTGDCYSGDENPD 439
+C C VG G C C GY S C+PC C A CD TG C + EN
Sbjct: 308 KCQCKVGVIGSICDRCQDGYYGFSKN-----GCLPCQCNNRSASCDALTGACLNCQENSK 362
Query: 440 -IECADCPIGFYNDPHDPRSCKPCPCH---NGFSCSVMPETEEVVCNNCPPGVTGARCEL 495
C +C GFY P + C CPC + SCS+ E C+ C G G C
Sbjct: 363 GNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNK 422
Query: 496 CADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGN-CDRLTGRCLKCIHNTAGIYCDQCK 554
C +GY+ C+ CQC+ +VDP + C +G C+ C+HNT G +C+ C
Sbjct: 423 CENGYYNFD-------SICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCL 475
Query: 555 AGYFGD 560
GY D
Sbjct: 476 EGYVHD 481
Score = 110 bits (276), Expect = 6e-24
Identities = 68/204 (33%), Positives = 95/204 (46%), Gaps = 41/204 (20%)
Query: 416 CNCQGGGA-----CDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSC 470
CNC G+ C+ TG C + C C GFY + + C+PC C +
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLN-YTSGLCQPCDCSPHGAL 299
Query: 471 SVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGN 530
S+ P C C GV G+ C+ C DGY+G F ++G C PCQCNN S +
Sbjct: 300 SI-PCNSSGKCQ-CKVGVIGSICDRCQDGYYG--FSKNG----CLPCQCNNR-----SAS 346
Query: 531 CDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGT 590
CD LTG CL C N+ G +C++CK G++ +P+ +C C C+ + S G+
Sbjct: 347 CDALTGACLNCQENSKGNHCEECKEGFY---QSPDATKECLRCPCSAV-------TSTGS 396
Query: 591 C------------VCKPGFGGPNC 602
C CK G+ GPNC
Sbjct: 397 CSIKSSELEPECDQCKDGYIGPNC 420
Score = 106 bits (264), Expect = 1e-22
Identities = 64/205 (31%), Positives = 92/205 (44%), Gaps = 33/205 (16%)
Query: 1 MPALWLGCCLCFSLL-------------LPAARATSRREVCDCNGKSRQCIFDRELHRQT 47
MP +LG C S L L + A VC+C+ + ++R
Sbjct: 201 MPQKYLGKYACESNLKSKYLPLTQPVMNLRVSEAVKTEYVCNCS-----VVGSLNVNRCN 255
Query: 48 GNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPG 107
+C C G+HCE CK GFY + C PC+C+ G+LS C++SG+C CK G
Sbjct: 256 QTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKVG 314
Query: 108 VTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDA--GRCV-CKPAVTGE 164
V G+ CDRC G++ + GC C C+ + CDA G C+ C+ G
Sbjct: 315 VIGSICDRCQDGYYGFSKNGCL--------PCQCN--NRSASCDALTGACLNCQENSKGN 364
Query: 165 RCDRCRSGYYNLDGGNPEGCTQCFC 189
C+ C+ G+Y E C +C C
Sbjct: 365 HCEECKEGFYQSPDATKE-CLRCPC 388
Score = 95.1 bits (235), Expect = 3e-19
Identities = 49/117 (41%), Positives = 66/117 (56%), Gaps = 14/117 (11%)
Query: 84 CNCNSKGSLSA-RCDNS-GRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDC 141
CNC+ GSL+ RC+ + G+C C+PG G C+ C GF++ +G Q CDC
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQP-------CDC 293
Query: 142 DPAG-IAGPCDA-GRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASC 196
P G ++ PC++ G+C CK V G CDRC+ GYY G + GC C C SASC
Sbjct: 294 SPHGALSIPCNSSGKCQCKVGVIGSICDRCQDGYY---GFSKNGCLPCQCNNRSASC 347
Score = 80.5 bits (197), Expect = 8e-15
Identities = 60/181 (33%), Positives = 81/181 (44%), Gaps = 41/181 (22%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR-CLPCNC 86
C CN +S C TG CLNC +N+ G HCE+CK GFY+ + + CL C C
Sbjct: 338 CQCNNRSASC------DALTG---ACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPC 388
Query: 87 N---SKGSLSARCDN-SGRCS-CKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDC 141
+ S GS S + C CK G G C++C G++ D+ C KC C
Sbjct: 389 SAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGYYNF-DSICR--------KCQC 439
Query: 142 ----DPAGIAGPC--DAGRCV-CKPAVTGERCDRCRSGY-YNLDGG---------NPEGC 184
DP C ++G C+ C TG C+ C GY ++L+G PEG
Sbjct: 440 HGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEGNCIKKEVILPTPEGS 499
Query: 185 T 185
T
Sbjct: 500 T 500
Score = 58.2 bits (139), Expect = 4e-08
Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 6/86 (6%)
Query: 519 CNNNVDPSASGN-CDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNP 577
CN +V S + N C++ TG+C +C G++C+ CK G++ + + C+ C+C+P
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLN----YTSGLCQPCDCSP 295
Query: 578 MGSEPVGCRSDGTCVCKPGFGGPNCE 603
G+ + C S G C CK G G C+
Sbjct: 296 HGALSIPCNSSGKCQCKVGVIGSICD 321
>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
Length = 1724
Score = 114 bits (286), Expect = 4e-25
Identities = 169/721 (23%), Positives = 290/721 (40%), Gaps = 129/721 (17%)
Query: 394 QDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPDIE-CADCPIGFY- 450
Q C+ GY RD L G C+PCNC G C +G C + N E C C G+Y
Sbjct: 57 QGCSPGYYRDHKGLYT-GRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYG 115
Query: 451 NDPHDPRSCKPCPCH--NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEH 508
N H SC+ CPC N F+ + +V C+ C G TG +CE CA GYFG+P
Sbjct: 116 NAVHG--SCRACPCPHTNSFATGCVVNGGDVRCS-CKAGYTGTQCERCAPGYFGNPQKFG 172
Query: 509 GPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPAD 568
G CQPC CN+N G+C LTG C+ +P +PA+
Sbjct: 173 G---SCQPCSCNSN---GQLGSCHPLTGDCIN------------------QEPKDSSPAE 208
Query: 569 KCRAC-NCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAF-SCPACYNQVKIQMDQFMQQ 626
+C C +C + + + K G + G Q K +Q +
Sbjct: 209 ECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNY 268
Query: 627 LQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRS 686
+ SK +G LE + Q + + AQ++ +++L
Sbjct: 269 RSAISNHGSKIEG---------LERELTDLNQEFETLQEKAQVNSRKAQTLN-------- 311
Query: 687 QENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASD 746
+++ + + L + +N +R+ H L+ Q+ + E GN N+P+ D
Sbjct: 312 ---------NNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGE-----GN-NVPSGD 356
Query: 747 HYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRK-----ALHEGV 801
F EA R+ N + RE E +++ L+ + H+G
Sbjct: 357 -------FSREWAEAQRMMRE--LRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGE 407
Query: 802 GSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGV 861
+G + ++ L E K L +L A QA+ +A+ Q + R L ++ R Q
Sbjct: 408 NNGLAN---SIRDSLNEYEAKLSDLRARLQEAAAQAK-QANGLNQENERALGAIQR-QVK 462
Query: 862 SDQSFQVEEAKRIKQKADSL--SSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREK 919
S Q + K + SL +++ + M++ ++ + L EA+Q E
Sbjct: 463 EINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQ---------EL 513
Query: 920 SDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVD--NRKAEAEEAMKRLS 977
SD++ L++S + +L E E ++L+E Q++ R A +E ++
Sbjct: 514 SDKV---RELSRSAGKTSL------VEEAEKHARSLQELAKQLEEIKRNASGDELVR--- 561
Query: 978 YISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALE--ISSEIEQEIGSLNLEANVT 1035
DA+ + A+ +A A RA + + AL+ I ++ ++ +L+ ++
Sbjct: 562 ----CAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKL 617
Query: 1036 ADGALAMEKGLASLKSEMREVEGELE--------RKELEFDTNMDAVQMVITEAQKVDTR 1087
+ A +K LK E+ L+ +KE+ DTN+ ++ + Q+ D
Sbjct: 618 LNEAKMTQK---KLKQEVSPALNNLQQTLNIVTVQKEV-IDTNLTTLRDGLHGIQRGDID 673
Query: 1088 A 1088
A
Sbjct: 674 A 674
Score = 98.6 bits (244), Expect = 3e-20
Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 22/158 (13%)
Query: 22 TSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRC 81
T R C+CNG S QC Q G+G C+NC NT G HCE+C+ G+Y + C
Sbjct: 72 TGRCVPCNCNGHSNQC--------QDGSGI-CVNCQHNTAGEHCERCQEGYYGNAVHGSC 122
Query: 82 LPCNCNSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSK 138
C C S + C +G RCSCK G TG +C+RC PG+ G Q
Sbjct: 123 RACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF-----GNPQKFGGSCQP 177
Query: 139 CDCDPAGIAGPCD--AGRCV---CKPAVTGERCDRCRS 171
C C+ G G C G C+ K + E CD C S
Sbjct: 178 CSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215
Score = 67.8 bits (164), Expect = 5e-11
Identities = 48/145 (33%), Positives = 62/145 (42%), Gaps = 30/145 (20%)
Query: 68 CKNGFYRHRE---RDRCLPCNCNSKGSLSARC-DNSGRC-SCKPGVTGARCDRCLPGFHM 122
C G+YR + RC+PCNCN S +C D SG C +C+ G C+RC G++
Sbjct: 59 CSPGYYRDHKGLYTGRCVPCNCNGH---SNQCQDGSGICVNCQHNTAGEHCERCQEGYYG 115
Query: 123 LTDAGCTQDQRLLDSKCDCDPAG-IAGPCDAG----RCVCKPAVTGERCDRCRSGYYNLD 177
G + C C A C RC CK TG +C+RC GY+
Sbjct: 116 NAVHGSCR-------ACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF--- 165
Query: 178 GGNPE----GCTQCFC--YGHSASC 196
GNP+ C C C G SC
Sbjct: 166 -GNPQKFGGSCQPCSCNSNGQLGSC 189
Score = 59.3 bits (142), Expect = 2e-08
Identities = 29/71 (40%), Positives = 38/71 (53%), Gaps = 8/71 (11%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG---GACDPDTGDCYS---G 434
+C C GY G C+ CA GY + + G G+C PC+C G+C P TGDC +
Sbjct: 145 RCSCKAGYTGTQCERCAPGYFGNPQKFG--GSCQPCSCNSNGQLGSCHPLTGDCINQEPK 202
Query: 435 DENPDIECADC 445
D +P EC DC
Sbjct: 203 DSSPAEECDDC 213
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 105 bits (263), Expect = 2e-22
Identities = 68/206 (33%), Positives = 96/206 (46%), Gaps = 41/206 (19%)
Query: 28 CDCNGKSRQCIFDREL------HRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR- 80
C CN S+ C ++ + H + G G C +C NT G +CE CK+ F+R D
Sbjct: 575 CQCNSHSKSCHYNISVDPFPFEHFRGGGGV-CDDCEHNTTGRNCELCKDYFFRQVGADPS 633
Query: 81 ----CLPCNCNSKGSL--SARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQ 130
C PC+C++ G+ S CD G+C+CK V+G +C++C GF+ L + GC
Sbjct: 634 AIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGC-- 691
Query: 131 DQRLLDSKCDCDPAG-----IAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCT 185
S C+C+ +G I ++G+C CK V G RCD C G+ L N GC
Sbjct: 692 ------SPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCE 745
Query: 186 QC----------FCYGHSASCRSSAE 201
C FC HS C E
Sbjct: 746 PCQCNLHGSVNKFCNPHSGQCECKKE 771
Score = 101 bits (251), Expect = 4e-21
Identities = 58/150 (38%), Positives = 73/150 (48%), Gaps = 21/150 (14%)
Query: 50 GFRCLNCNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCNSKGSLSARC---DNSGRCSC 104
G +C NC + G C +C+NGFY +E D C PCNCN+ G++ NSG+C C
Sbjct: 659 GGQC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKC 717
Query: 105 KPGVTGARCDRCLPGFHML---TDAGCTQDQRLLDSKCD--CDPAGIAGPCDAGRCVCKP 159
K V G RCD C GF L D GC Q L + C+P +G+C CK
Sbjct: 718 KANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNP-------HSGQCECKK 770
Query: 160 AVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
G +CD CR +Y LD N C C C
Sbjct: 771 EAKGLQCDTCRENFYGLDVTN---CKACDC 797
Score = 101 bits (251), Expect = 4e-21
Identities = 74/240 (30%), Positives = 99/240 (41%), Gaps = 37/240 (15%)
Query: 381 QCICPVGYKGQFCQDCASG--YKRDSARLGPFGTCIPCNCQGGGA------CDPDTGDCY 432
QCIC +G+ C C G Y R + C+PCNC G C+ TG C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSF----LCLPCNCDKTGTINGSLLCNKSTGQCP 869
Query: 433 SGDENPDIECADCPIGFYNDPHDP-RSCKPCPCHNGFSCSVMPETEEVVCNN------CP 485
+ C C YN D + C+ C C S +P T +C+ C
Sbjct: 870 CKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECD---SLGTLPGT---ICDPISGQCLCV 923
Query: 486 PGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNT 545
P G RC C G++ P G C PC C+ + + C+ LTG+C+ +
Sbjct: 924 PNRQGRRCNQCQPGFYISP----GNATGCLPCSCHTT--GAVNHICNSLTGQCVCQDASI 977
Query: 546 AGIYCDQCKAGYFG-DPLAPNPADKCRACNCNPMGSEPVGCR-SDGTCVCKPGFGGPNCE 603
AG CDQCK YFG DP +C+ CNC+ G+ C G C CK G C+
Sbjct: 978 AGQRCDQCKDHYFGFDP----QTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCD 1033
Score = 95.5 bits (236), Expect = 2e-19
Identities = 71/237 (29%), Positives = 98/237 (41%), Gaps = 34/237 (14%)
Query: 381 QCICPVGYKGQFCQDCASGYK--RDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSG 434
QC C G C C G+K R +G C PC C G+ C+P +G C
Sbjct: 714 QCKCKANVIGLRCDHCNFGFKFLRSFNDVG----CEPCQCNLHGSVNKFCNPHSGQCECK 769
Query: 435 DENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNN------CPPGV 488
E ++C C FY D +CK C C S +P T VCN C P V
Sbjct: 770 KEAKGLQCDTCRENFYG--LDVTNCKACDCDTAGS---LPGT---VCNAKTGQCICKPNV 821
Query: 489 TGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGI 548
G +C C +G F + C PC C+ + S C++ TG+C C G+
Sbjct: 822 EGRQCNKCLEGNF---YLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC-PCKLGVTGL 877
Query: 549 YCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD---GTCVCKPGFGGPNC 602
C+QC+ + L + C+ C C+ +G+ P G D G C+C P G C
Sbjct: 878 RCNQCEPHRYN--LTIDNFQHCQMCECDSLGTLP-GTICDPISGQCLCVPNRQGRRC 931
Score = 91.7 bits (226), Expect = 4e-18
Identities = 63/218 (28%), Positives = 94/218 (43%), Gaps = 30/218 (13%)
Query: 416 CNCQG-GGACDPDTGD----CYSGDENPDIECADCPIGFYNDPHDPR-------SCKPCP 463
C C G CD + C + C C + YND + +CKPC
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRC-LPLYNDKPFRQGDQVYAFNCKPCQ 576
Query: 464 CHNG-----FSCSVMPETEEV------VCNNCPPGVTGARCELCADGYFGDPFGEHGPVR 512
C++ ++ SV P E VC++C TG CELC D +F + +
Sbjct: 577 CNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAID 636
Query: 513 PCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRA 572
C+PC C+ + S CD++ G+C C + +G C+QC+ G++ L D C
Sbjct: 637 VCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYN--LQELDPDGCSP 693
Query: 573 CNCNPMGS--EPVGC-RSDGTCVCKPGFGGPNCEHGAF 607
CNCN G+ + C ++ G C CK G C+H F
Sbjct: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNF 731
Score = 89.4 bits (220), Expect = 2e-17
Identities = 48/141 (34%), Positives = 66/141 (46%), Gaps = 13/141 (9%)
Query: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNS--GRCSCKPGVTGARC 113
C G+ C+ C+ FY + C C+C++ GSL N+ G+C CKP V G +C
Sbjct: 768 CKKEAKGLQCDTCRENFYG-LDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQC 826
Query: 114 DRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPC-----DAGRCVCKPAVTGERCDR 168
++CL G L Q+ L C+CD G G+C CK VTG RC++
Sbjct: 827 NKCLEGNFYLR-----QNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQ 881
Query: 169 CRSGYYNLDGGNPEGCTQCFC 189
C YNL N + C C C
Sbjct: 882 CEPHRYNLTIDNFQHCQMCEC 902
Score = 89.0 bits (219), Expect = 2e-17
Identities = 57/183 (31%), Positives = 74/183 (40%), Gaps = 24/183 (13%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-----GGACDPDTGDCYSGD 435
QC C +G G C C R + + F C C C G CDP +G C
Sbjct: 867 QCPCKLGVTGLRCNQCEP--HRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVP 924
Query: 436 ENPDIECADCPIGFYNDPHDPRSCKPCPCHN----GFSCSVMPETEEVVCNNCPPGVTGA 491
C C GFY P + C PC CH C+ + T + VC + + G
Sbjct: 925 NRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSL--TGQCVCQDA--SIAGQ 980
Query: 492 RCELCADGYFG-DPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYC 550
RC+ C D YFG DP CQPC C ++ + + C +TG+C C G C
Sbjct: 981 RCDQCKDHYFGFDP-----QTGRCQPCNC--HLSGALNETCHLVTGQCF-CKQFVTGSKC 1032
Query: 551 DQC 553
D C
Sbjct: 1033 DAC 1035
Score = 88.6 bits (218), Expect = 3e-17
Identities = 69/237 (29%), Positives = 96/237 (40%), Gaps = 33/237 (13%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPD------TGDCYSG 434
QC C G+ C C +G+ + L P G C PCNC G D D +G C
Sbjct: 661 QCNCKRHVSGRQCNQCQNGFY-NLQELDPDG-CSPCNCNTSGTVDGDITCHQNSGQCKCK 718
Query: 435 DENPDIECADCPIGF-----YNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVT 489
+ C C GF +ND C+PC C+ S + C C
Sbjct: 719 ANVIGLRCDHCNFGFKFLRSFNDV----GCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAK 773
Query: 490 GARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGN-CDRLTGRCLKCIHNTAGI 548
G +C+ C + ++G V C+ C C + S G C+ TG+C+ C N G
Sbjct: 774 GLQCDTCRENFYG------LDVTNCKACDC--DTAGSLPGTVCNAKTGQCI-CKPNVEGR 824
Query: 549 YCDQCKAGYFGDPLAPNPADKCRACNCNPMGS---EPVGCRSDGTCVCKPGFGGPNC 602
C++C G F L N + C CNC+ G+ + +S G C CK G G C
Sbjct: 825 QCNKCLEGNF--YLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRC 879
Score = 83.2 bits (204), Expect = 1e-15
Identities = 58/193 (30%), Positives = 84/193 (43%), Gaps = 45/193 (23%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDN-TDGIHCEKCKNGFYRH--RERDR---- 80
C C+G + C T +RCL ++ T+G+HC++C + R+ D+
Sbjct: 518 CQCHGHADNC-------DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAF 570
Query: 81 -CLPCNCNSKGSLSARCD---------------NSGRCS-CKPGVTGARCDRCLPGFHML 123
C PC CNS S C G C C+ TG C+ C F
Sbjct: 571 NCKPCQCNSH---SKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQ 627
Query: 124 TDAGCTQDQRLLD--SKCDCDPAGIAGP---CD--AGRCVCKPAVTGERCDRCRSGYYNL 176
A D +D CDCD G CD G+C CK V+G +C++C++G+YNL
Sbjct: 628 VGA----DPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNL 683
Query: 177 DGGNPEGCTQCFC 189
+P+GC+ C C
Sbjct: 684 QELDPDGCSPCNC 696
Score = 79.7 bits (195), Expect = 1e-14
Identities = 62/218 (28%), Positives = 89/218 (40%), Gaps = 44/218 (20%)
Query: 8 CCLCFSLLLPAARATSRREVCDCNGKSRQC--IFDRELHRQTGNGFRCLNCN-DNTD--- 61
C SL A + + +C N + RQC + + + N F CL CN D T
Sbjct: 797 CDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTIN 856
Query: 62 -------------------GIHCEKCKNGFYRHR--ERDRCLPCNCNSKGSLSAR-CDN- 98
G+ C +C+ Y C C C+S G+L CD
Sbjct: 857 GSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPI 916
Query: 99 SGRCSCKPGVTGARCDRCLPGFHML--TDAGCTQDQRLLDSKCDCDPAGIAGP-CDA--G 153
SG+C C P G RC++C PGF++ GC C C G C++ G
Sbjct: 917 SGQCLCVPNRQGRRCNQCQPGFYISPGNATGCL--------PCSCHTTGAVNHICNSLTG 968
Query: 154 RCVCKPA-VTGERCDRCRSGYYNLDGGNPEGCTQCFCY 190
+CVC+ A + G+RCD+C+ Y+ D C C C+
Sbjct: 969 QCVCQDASIAGQRCDQCKDHYFGFDPQTGR-CQPCNCH 1005
Score = 73.6 bits (179), Expect = 1e-12
Identities = 45/141 (31%), Positives = 69/141 (48%), Gaps = 13/141 (9%)
Query: 52 RCLNCNDNTDGIHCEKCKNGFY-RHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPG-V 108
+CL C N G C +C+ GFY CLPC+C++ G+++ C++ +G+C C+ +
Sbjct: 919 QCL-CVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASI 977
Query: 109 TGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGER 165
G RCD+C + Q C+C +G C G+C CK VTG +
Sbjct: 978 AGQRCDQCKDHYFGF------DPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSK 1031
Query: 166 CDRCRSGYYNLDGGNPEGCTQ 186
CD C +LD N GC++
Sbjct: 1032 CDACVPSASHLDVNNLLGCSK 1052
Score = 33.1 bits (74), Expect = 1.5
Identities = 24/77 (31%), Positives = 29/77 (37%), Gaps = 13/77 (16%)
Query: 131 DQRLLDSKCDCDPAGIAGPCDAG----RCVCKPA--VTGERCDRCRSGYYNL-----DGG 179
D+ + +C C G A CD RC+C G CDRC Y + D
Sbjct: 510 DEITISGRCQCH--GHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQV 567
Query: 180 NPEGCTQCFCYGHSASC 196
C C C HS SC
Sbjct: 568 YAFNCKPCQCNSHSKSC 584
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 105 bits (263), Expect = 2e-22
Identities = 68/206 (33%), Positives = 96/206 (46%), Gaps = 41/206 (19%)
Query: 28 CDCNGKSRQCIFDREL------HRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR- 80
C CN S+ C ++ + H + G G C +C NT G +CE CK+ F+R D
Sbjct: 575 CQCNSHSKSCHYNISVDPFPFEHFRGGGGV-CDDCEHNTTGRNCELCKDYFFRQVGADPS 633
Query: 81 ----CLPCNCNSKGSL--SARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQ 130
C PC+C++ G+ S CD G+C+CK V+G +C++C GF+ L + GC
Sbjct: 634 AIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGC-- 691
Query: 131 DQRLLDSKCDCDPAG-----IAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCT 185
S C+C+ +G I ++G+C CK V G RCD C G+ L N GC
Sbjct: 692 ------SPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCE 745
Query: 186 QC----------FCYGHSASCRSSAE 201
C FC HS C E
Sbjct: 746 PCQCNLHGSVNKFCNPHSGQCECKKE 771
Score = 101 bits (251), Expect = 4e-21
Identities = 58/150 (38%), Positives = 73/150 (48%), Gaps = 21/150 (14%)
Query: 50 GFRCLNCNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCNSKGSLSARC---DNSGRCSC 104
G +C NC + G C +C+NGFY +E D C PCNCN+ G++ NSG+C C
Sbjct: 659 GGQC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKC 717
Query: 105 KPGVTGARCDRCLPGFHML---TDAGCTQDQRLLDSKCD--CDPAGIAGPCDAGRCVCKP 159
K V G RCD C GF L D GC Q L + C+P +G+C CK
Sbjct: 718 KANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNP-------HSGQCECKK 770
Query: 160 AVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
G +CD CR +Y LD N C C C
Sbjct: 771 EAKGLQCDTCRENFYGLDVTN---CKACDC 797
Score = 101 bits (251), Expect = 4e-21
Identities = 74/240 (30%), Positives = 99/240 (41%), Gaps = 37/240 (15%)
Query: 381 QCICPVGYKGQFCQDCASG--YKRDSARLGPFGTCIPCNCQGGGA------CDPDTGDCY 432
QCIC +G+ C C G Y R + C+PCNC G C+ TG C
Sbjct: 814 QCICKPNVEGRQCNKCLEGNFYLRQNNSF----LCLPCNCDKTGTINGSLLCNKSTGQCP 869
Query: 433 SGDENPDIECADCPIGFYNDPHDP-RSCKPCPCHNGFSCSVMPETEEVVCNN------CP 485
+ C C YN D + C+ C C S +P T +C+ C
Sbjct: 870 CKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECD---SLGTLPGT---ICDPISGQCLCV 923
Query: 486 PGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNT 545
P G RC C G++ P G C PC C+ + + C+ LTG+C+ +
Sbjct: 924 PNRQGRRCNQCQPGFYISP----GNATGCLPCSCHTT--GAVNHICNSLTGQCVCQDASI 977
Query: 546 AGIYCDQCKAGYFG-DPLAPNPADKCRACNCNPMGSEPVGCR-SDGTCVCKPGFGGPNCE 603
AG CDQCK YFG DP +C+ CNC+ G+ C G C CK G C+
Sbjct: 978 AGQRCDQCKDHYFGFDP----QTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCD 1033
Score = 95.5 bits (236), Expect = 2e-19
Identities = 71/237 (29%), Positives = 98/237 (41%), Gaps = 34/237 (14%)
Query: 381 QCICPVGYKGQFCQDCASGYK--RDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSG 434
QC C G C C G+K R +G C PC C G+ C+P +G C
Sbjct: 714 QCKCKANVIGLRCDHCNFGFKFLRSFNDVG----CEPCQCNLHGSVNKFCNPHSGQCECK 769
Query: 435 DENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNN------CPPGV 488
E ++C C FY D +CK C C S +P T VCN C P V
Sbjct: 770 KEAKGLQCDTCRENFYG--LDVTNCKACDCDTAGS---LPGT---VCNAKTGQCICKPNV 821
Query: 489 TGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGI 548
G +C C +G F + C PC C+ + S C++ TG+C C G+
Sbjct: 822 EGRQCNKCLEGNF---YLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC-PCKLGVTGL 877
Query: 549 YCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD---GTCVCKPGFGGPNC 602
C+QC+ + L + C+ C C+ +G+ P G D G C+C P G C
Sbjct: 878 RCNQCEPHRYN--LTIDNFQHCQMCECDSLGTLP-GTICDPISGQCLCVPNRQGRRC 931
Score = 91.7 bits (226), Expect = 4e-18
Identities = 63/218 (28%), Positives = 94/218 (43%), Gaps = 30/218 (13%)
Query: 416 CNCQG-GGACDPDTGD----CYSGDENPDIECADCPIGFYNDPHDPR-------SCKPCP 463
C C G CD + C + C C + YND + +CKPC
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRC-LPLYNDKPFRQGDQVYAFNCKPCQ 576
Query: 464 CHNG-----FSCSVMPETEEV------VCNNCPPGVTGARCELCADGYFGDPFGEHGPVR 512
C++ ++ SV P E VC++C TG CELC D +F + +
Sbjct: 577 CNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAID 636
Query: 513 PCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRA 572
C+PC C+ + S CD++ G+C C + +G C+QC+ G++ L D C
Sbjct: 637 VCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYN--LQELDPDGCSP 693
Query: 573 CNCNPMGS--EPVGC-RSDGTCVCKPGFGGPNCEHGAF 607
CNCN G+ + C ++ G C CK G C+H F
Sbjct: 694 CNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNF 731
Score = 89.4 bits (220), Expect = 2e-17
Identities = 48/141 (34%), Positives = 66/141 (46%), Gaps = 13/141 (9%)
Query: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNS--GRCSCKPGVTGARC 113
C G+ C+ C+ FY + C C+C++ GSL N+ G+C CKP V G +C
Sbjct: 768 CKKEAKGLQCDTCRENFYG-LDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQC 826
Query: 114 DRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPC-----DAGRCVCKPAVTGERCDR 168
++CL G L Q+ L C+CD G G+C CK VTG RC++
Sbjct: 827 NKCLEGNFYLR-----QNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQ 881
Query: 169 CRSGYYNLDGGNPEGCTQCFC 189
C YNL N + C C C
Sbjct: 882 CEPHRYNLTIDNFQHCQMCEC 902
Score = 89.0 bits (219), Expect = 2e-17
Identities = 57/183 (31%), Positives = 74/183 (40%), Gaps = 24/183 (13%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-----GGACDPDTGDCYSGD 435
QC C +G G C C R + + F C C C G CDP +G C
Sbjct: 867 QCPCKLGVTGLRCNQCEP--HRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVP 924
Query: 436 ENPDIECADCPIGFYNDPHDPRSCKPCPCHN----GFSCSVMPETEEVVCNNCPPGVTGA 491
C C GFY P + C PC CH C+ + T + VC + + G
Sbjct: 925 NRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSL--TGQCVCQDA--SIAGQ 980
Query: 492 RCELCADGYFG-DPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYC 550
RC+ C D YFG DP CQPC C ++ + + C +TG+C C G C
Sbjct: 981 RCDQCKDHYFGFDP-----QTGRCQPCNC--HLSGALNETCHLVTGQCF-CKQFVTGSKC 1032
Query: 551 DQC 553
D C
Sbjct: 1033 DAC 1035
Score = 88.6 bits (218), Expect = 3e-17
Identities = 69/237 (29%), Positives = 96/237 (40%), Gaps = 33/237 (13%)
Query: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPD------TGDCYSG 434
QC C G+ C C +G+ + L P G C PCNC G D D +G C
Sbjct: 661 QCNCKRHVSGRQCNQCQNGFY-NLQELDPDG-CSPCNCNTSGTVDGDITCHQNSGQCKCK 718
Query: 435 DENPDIECADCPIGF-----YNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVT 489
+ C C GF +ND C+PC C+ S + C C
Sbjct: 719 ANVIGLRCDHCNFGFKFLRSFNDV----GCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAK 773
Query: 490 GARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGN-CDRLTGRCLKCIHNTAGI 548
G +C+ C + ++G V C+ C C + S G C+ TG+C+ C N G
Sbjct: 774 GLQCDTCRENFYG------LDVTNCKACDC--DTAGSLPGTVCNAKTGQCI-CKPNVEGR 824
Query: 549 YCDQCKAGYFGDPLAPNPADKCRACNCNPMGS---EPVGCRSDGTCVCKPGFGGPNC 602
C++C G F L N + C CNC+ G+ + +S G C CK G G C
Sbjct: 825 QCNKCLEGNF--YLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRC 879
Score = 83.2 bits (204), Expect = 1e-15
Identities = 58/193 (30%), Positives = 84/193 (43%), Gaps = 45/193 (23%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDN-TDGIHCEKCKNGFYRH--RERDR---- 80
C C+G + C T +RCL ++ T+G+HC++C + R+ D+
Sbjct: 518 CQCHGHADNC-------DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAF 570
Query: 81 -CLPCNCNSKGSLSARCD---------------NSGRCS-CKPGVTGARCDRCLPGFHML 123
C PC CNS S C G C C+ TG C+ C F
Sbjct: 571 NCKPCQCNSH---SKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQ 627
Query: 124 TDAGCTQDQRLLD--SKCDCDPAGIAGP---CD--AGRCVCKPAVTGERCDRCRSGYYNL 176
A D +D CDCD G CD G+C CK V+G +C++C++G+YNL
Sbjct: 628 VGA----DPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNL 683
Query: 177 DGGNPEGCTQCFC 189
+P+GC+ C C
Sbjct: 684 QELDPDGCSPCNC 696
Score = 79.7 bits (195), Expect = 1e-14
Identities = 62/218 (28%), Positives = 89/218 (40%), Gaps = 44/218 (20%)
Query: 8 CCLCFSLLLPAARATSRREVCDCNGKSRQC--IFDRELHRQTGNGFRCLNCN-DNTD--- 61
C SL A + + +C N + RQC + + + N F CL CN D T
Sbjct: 797 CDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTIN 856
Query: 62 -------------------GIHCEKCKNGFYRHR--ERDRCLPCNCNSKGSLSAR-CDN- 98
G+ C +C+ Y C C C+S G+L CD
Sbjct: 857 GSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPI 916
Query: 99 SGRCSCKPGVTGARCDRCLPGFHML--TDAGCTQDQRLLDSKCDCDPAGIAGP-CDA--G 153
SG+C C P G RC++C PGF++ GC C C G C++ G
Sbjct: 917 SGQCLCVPNRQGRRCNQCQPGFYISPGNATGCL--------PCSCHTTGAVNHICNSLTG 968
Query: 154 RCVCKPA-VTGERCDRCRSGYYNLDGGNPEGCTQCFCY 190
+CVC+ A + G+RCD+C+ Y+ D C C C+
Sbjct: 969 QCVCQDASIAGQRCDQCKDHYFGFDPQTGR-CQPCNCH 1005
Score = 73.6 bits (179), Expect = 1e-12
Identities = 45/141 (31%), Positives = 69/141 (48%), Gaps = 13/141 (9%)
Query: 52 RCLNCNDNTDGIHCEKCKNGFY-RHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPG-V 108
+CL C N G C +C+ GFY CLPC+C++ G+++ C++ +G+C C+ +
Sbjct: 919 QCL-CVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASI 977
Query: 109 TGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGER 165
G RCD+C + Q C+C +G C G+C CK VTG +
Sbjct: 978 AGQRCDQCKDHYFGF------DPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSK 1031
Query: 166 CDRCRSGYYNLDGGNPEGCTQ 186
CD C +LD N GC++
Sbjct: 1032 CDACVPSASHLDVNNLLGCSK 1052
Score = 33.1 bits (74), Expect = 1.5
Identities = 24/77 (31%), Positives = 29/77 (37%), Gaps = 13/77 (16%)
Query: 131 DQRLLDSKCDCDPAGIAGPCDAG----RCVCKPA--VTGERCDRCRSGYYNL-----DGG 179
D+ + +C C G A CD RC+C G CDRC Y + D
Sbjct: 510 DEITISGRCQCH--GHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQV 567
Query: 180 NPEGCTQCFCYGHSASC 196
C C C HS SC
Sbjct: 568 YAFNCKPCQCNSHSKSC 584
>gi|5453810 netrin 3 [Homo sapiens]
Length = 580
Score = 105 bits (261), Expect = 3e-22
Identities = 64/179 (35%), Positives = 83/179 (46%), Gaps = 24/179 (13%)
Query: 7 GCCLCFSLLLPAARATSRRE----VCDCNGKSRQCIFDRELHRQTG--NGFRCLNCNDNT 60
G C F P RAT+R C CNG +R+C F+ EL+R +G +G CLNC NT
Sbjct: 286 GRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNT 345
Query: 61 DGIHCEKCKNGFYRH-----RERDRCLPCNCNSKGSLSARCD-NSGRCSCKPGVTGARCD 114
G HC C+ GFYR +R C C+C+ G+ C+ +G+C CK GVTG C+
Sbjct: 346 AGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCN 405
Query: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGY 173
RC PGF Q+ C I GP + V +P C R Y
Sbjct: 406 RCAPGF-----------QQSRSPVAPCVKTPIPGPTEDSSPV-QPQDCDSHCKPARGSY 452
Score = 79.0 bits (193), Expect = 2e-14
Identities = 51/156 (32%), Positives = 72/156 (46%), Gaps = 13/156 (8%)
Query: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRP---CQPCQ 518
C C NG + + +T+ + +C G G C C Y P+ + R C C
Sbjct: 255 CKC-NGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPW-QRATARESHACLACS 312
Query: 519 CNNNVDPSASG-NCDRLTGR-----CLKCIHNTAGIYCDQCKAGYFGDP-LAPNPADKCR 571
CN + RL+GR CL C HNTAG +C C+ G++ DP A + CR
Sbjct: 313 CNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACR 372
Query: 572 ACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEHGA 606
AC+C+P+G+ C ++ G C CK G G C A
Sbjct: 373 ACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCA 408
Score = 50.1 bits (118), Expect = 1e-05
Identities = 49/184 (26%), Positives = 65/184 (35%), Gaps = 48/184 (26%)
Query: 382 CICPVGYKGQFCQDCASGY-----KRDSARLGPFGTCIPCNCQGGGACDPDTGDCY--SG 434
C C G +G C C Y +R +AR C+ C+C G + Y SG
Sbjct: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESH--ACLACSCNGHARRCRFNMELYRLSG 331
Query: 435 DENPDI-----------ECADCPIGFYNDP----HDPRSCKPCPCHNGFSCSVMPETEEV 479
+ + C C GFY DP D R+C+ C CH +T
Sbjct: 332 RRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCH---PVGAAGKTCNQ 388
Query: 480 VCNNCP--PGVTGARCELCADGYFGDPFGEHGPVRPC---------------QPCQCNNN 522
CP GVTG C CA G+ PV PC QP C+++
Sbjct: 389 TTGQCPCKDGVTGLTCNRCAPGF----QQSRSPVAPCVKTPIPGPTEDSSPVQPQDCDSH 444
Query: 523 VDPS 526
P+
Sbjct: 445 CKPA 448
Score = 43.1 bits (100), Expect = 0.001
Identities = 33/126 (26%), Positives = 44/126 (34%), Gaps = 22/126 (17%)
Query: 84 CNCNSKGSLSARC--DNSGR--CSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKC 139
C CN S RC D G C C+ G G C RC P + T + C
Sbjct: 255 CKCNGHAS---RCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLAC 311
Query: 140 DCDPAG-----------IAGPCDAGRCV-CKPAVTGERCDRCRSGYYNLDG---GNPEGC 184
C+ ++G G C+ C+ G C CR G+Y G + C
Sbjct: 312 SCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRAC 371
Query: 185 TQCFCY 190
C C+
Sbjct: 372 RACDCH 377
Score = 32.7 bits (73), Expect = 2.0
Identities = 15/52 (28%), Positives = 20/52 (38%), Gaps = 5/52 (9%)
Query: 155 CVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCFCYGHSASCRSSAE 201
C C+ G C RC+ Y + C C C GH+ CR + E
Sbjct: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNME 325
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 103 bits (256), Expect = 1e-21
Identities = 76/242 (31%), Positives = 108/242 (44%), Gaps = 60/242 (24%)
Query: 370 PVSGAPAPWVEQCICPVGYKGQFCQD-CASGYKRDSARLGPFGTCIPCNCQGGGACDPDT 428
P++GA C+C G++G C++ CA G +L PC C+ G +CDP
Sbjct: 156 PITGA-------CVCAAGFRGWRCEELCAPGTHGKGCQL-------PCQCRHGASCDPRA 201
Query: 429 GDCYSGDENPDIECAD-CPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPG 487
G+C + C + CP G + + R CPC NG +C + T E CPPG
Sbjct: 202 GECLCAPGYTGVYCEELCPPGSHGAHCELR----CPCQNGGTCHHI--TGECA---CPPG 252
Query: 488 VTGARC-ELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTA 546
TGA C + C G FG Q C C++ G CD +TG+C H TA
Sbjct: 253 WTGAVCAQPCPPGTFGQ--------NCSQDCPCHH------GGQCDHVTGQC----HCTA 294
Query: 547 GIYCDQCKA----GYFGDPLAPNPADKCRACNCNPMGSEPVGCR-SDGTCVCKPGFGGPN 601
G D+C+ G FG + + C+C+ G C + G C C+PG+ GP
Sbjct: 295 GYMGDRCQEECPFGSFGFQCSQH-------CDCHNGGQ----CSPTTGACECEPGYKGPR 343
Query: 602 CE 603
C+
Sbjct: 344 CQ 345
Score = 102 bits (254), Expect = 2e-21
Identities = 90/290 (31%), Positives = 108/290 (37%), Gaps = 77/290 (26%)
Query: 366 ISARPVSGAPAPWVEQCICPVGYKGQFCQD-CASGYKRDSARLGPFGTCIPCNCQGGGAC 424
IS PV+GA C C G+ G C + C GY D +L PC CQ G C
Sbjct: 370 ISCHPVTGA-------CTCQPGWSGHHCNESCPVGYYGDGCQL-------PCTCQNGADC 415
Query: 425 DPDTGDCYSGDENPDIECA-DCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNN 483
TG C CA C G Y P C C+NG +CS P C
Sbjct: 416 HSITGGCTCAPGFMGEVCAVSCAAGTYG----PNCSSICSCNNGGTCS--PVDGSCTCKE 469
Query: 484 ----------CPPGVTGARCE---LCADGYFGDPFGEHGPVRP------CQ-PC------ 517
CP G G C CA+G P P C+ PC
Sbjct: 470 GWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFG 529
Query: 518 -QCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQ-CKAGYFGDPLAPNPADKCRACN- 574
C+ + D S + CD +TG C C+ GI CD C G +G PN + C N
Sbjct: 530 LNCSEHCDCSHADGCDPVTGHCC-CLAGWTGIRCDSTCPPGRWG----PNCSVSCSCENG 584
Query: 575 --CNPMGSEPVGCRSDGTCVCKPGFGGPNCE---------HG-AFSCPAC 612
C+P DG+C C PGF GP C+ HG A CP C
Sbjct: 585 GSCSP---------EDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLC 625
Score = 97.4 bits (241), Expect = 6e-20
Identities = 76/231 (32%), Positives = 97/231 (41%), Gaps = 49/231 (21%)
Query: 382 CICPVGYKGQFC-QDCASGY-KRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPD 439
C C G+ G C Q CA GY +D A+L C+C G C P G C
Sbjct: 639 CECLPGFSGALCNQVCAGGYFGQDCAQL--------CSCANNGTCSPIDGSCQCFPGWIG 690
Query: 440 IECAD-CPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARC-ELCA 497
+C+ CP GF+ P C CHNG SCS E+ C+ C PG TG C + C
Sbjct: 691 KDCSQACPPGFWG----PACFHACSCHNGASCSA----EDGACH-CTPGWTGLFCTQRCP 741
Query: 498 DGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQ-CKAG 556
+FG G + CQC N +CD ++G+C C G +C+Q C G
Sbjct: 742 AAFFGKDCG--------RVCQCQNGA------SCDHISGKCT-CRTGFTGQHCEQRCAPG 786
Query: 557 YFGDPLAPNPADKCRACNC-NPMGSEPVGCRSDGTCVCKPGFGGPNCEHGA 606
FG + C C N + V GTC C PGF G C+ A
Sbjct: 787 TFGYGCQ-------QLCECMNNSTCDHV----TGTCYCSPGFKGIRCDQAA 826
Score = 88.2 bits (217), Expect = 4e-17
Identities = 79/246 (32%), Positives = 103/246 (41%), Gaps = 56/246 (22%)
Query: 377 PWVEQCICPVGYKGQFCQD-CASGYKRDSARLGPFGTCIPCNCQGGGACDPDTG--DCYS 433
P C C G+ G C C G R GP + C+C+ GG+C P+ G +C
Sbjct: 546 PVTGHCCCLAGWTGIRCDSTCPPG------RWGP-NCSVSCSCENGGSCSPEDGSCECAP 598
Query: 434 GDENPDIECADCPIGFYNDPHDPRSCKPCP--CHNGFSCSVMPETEEVVCNNCPPGVTGA 491
G P + CP GFY +PCP H+ C + +C C PG +GA
Sbjct: 599 GFRGPLCQ-RICPPGFYGH----GCAQPCPLCVHSSRPCHHI----SGIC-ECLPGFSGA 648
Query: 492 RC-ELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYC 550
C ++CA GYFG Q C C NN G C + G C +C G C
Sbjct: 649 LCNQVCAGGYFGQDC--------AQLCSCANN------GTCSPIDGSC-QCFPGWIGKDC 693
Query: 551 DQ-CKAGYFGDPLAPNPADKC-RACNCNPMGSEPVGCRS-DGTCVCKPGFGGPNCEHGAF 607
Q C G++G PA C AC+C+ S C + DG C C PG+ G C
Sbjct: 694 SQACPPGFWG------PA--CFHACSCHNGAS----CSAEDGACHCTPGWTGLFCTQ--- 738
Query: 608 SCPACY 613
CPA +
Sbjct: 739 RCPAAF 744
Score = 56.2 bits (134), Expect = 2e-07
Identities = 47/157 (29%), Positives = 61/157 (38%), Gaps = 36/157 (22%)
Query: 56 CNDNTDGIHCEKCKNGFYRHRERDRC----------LPCNCNSKGSLSARCDNSGRCSCK 105
C+ T HC G+ R ++ C C+C++ G S +G C C+
Sbjct: 283 CDHVTGQCHCTA---GYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSP---TTGACECE 336
Query: 106 PGVTGARCDR--CLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTG 163
PG G RC C G H GCT L CD D P G C C+P +G
Sbjct: 337 PGYKGPRCQERLCPEGLH---GPGCT-----LPCPCDADNTISCHPV-TGACTCQPGWSG 387
Query: 164 ERC-DRCRSGYYNLDGGNPEGC-TQCFCYGHSASCRS 198
C + C GYY +GC C C + A C S
Sbjct: 388 HHCNESCPVGYYG------DGCQLPCTCQ-NGADCHS 417
Score = 52.8 bits (125), Expect = 2e-06
Identities = 49/173 (28%), Positives = 64/173 (36%), Gaps = 39/173 (22%)
Query: 7 GCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRC------LNCNDNT 60
G C CF P + C C H NG C +C
Sbjct: 680 GSCQCF----PGWIGKDCSQACPPGFWGPACFHACSCH----NGASCSAEDGACHCTPGW 731
Query: 61 DGIHC-EKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD-RCL 117
G+ C ++C F+ +D C C + A CD+ SG+C+C+ G TG C+ RC
Sbjct: 732 TGLFCTQRCPAAFFG---KDCGRVCQCQN----GASCDHISGKCTCRTGFTGQHCEQRCA 784
Query: 118 PGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCD--AGRCVCKPAVTGERCDR 168
PG GC Q C+C CD G C C P G RCD+
Sbjct: 785 PG---TFGYGCQQ-------LCECMN---NSTCDHVTGTCYCSPGFKGIRCDQ 824
Score = 52.4 bits (124), Expect = 2e-06
Identities = 45/151 (29%), Positives = 57/151 (37%), Gaps = 37/151 (24%)
Query: 50 GFRCLNCNDN-TDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGV 108
GFR C + G H + C+ LPC C S R +G C C PG
Sbjct: 166 GFRGWRCEELCAPGTHGKGCQ------------LPCQCRHGASCDPR---AGECLCAPGY 210
Query: 109 TGARCDR-CLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCD 167
TG C+ C PG H A C + +C C G G C C P TG C
Sbjct: 211 TGVYCEELCPPGSH---GAHC-------ELRCPCQNGGTCHHI-TGECACPPGWTGAVCA 259
Query: 168 R-CRSGYYNLDGGNPEGCTQ-CFCYGHSASC 196
+ C G + + C+Q C C+ H C
Sbjct: 260 QPCPPGTFG------QNCSQDCPCH-HGGQC 283
Score = 52.0 bits (123), Expect = 3e-06
Identities = 45/135 (33%), Positives = 55/135 (40%), Gaps = 26/135 (19%)
Query: 56 CNDNTDGIHC-EKCKNGFYRHRERDRC-LPCNCNSKGSLSARCDN-SGRCSCKPGVTGAR 112
C G HC E C G+Y D C LPC C + A C + +G C+C PG G
Sbjct: 381 CQPGWSGHHCNESCPVGYYG----DGCQLPCTCQN----GADCHSITGGCTCAPGFMGEV 432
Query: 113 CD-RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCD-RCR 170
C C G + C+ S C C+ G P D G C CK G C C
Sbjct: 433 CAVSCAAGTY---GPNCS-------SICSCNNGGTCSPVD-GSCTCKEGWQGLDCTLPCP 481
Query: 171 SGYYNLDGGNPEGCT 185
SG + L+ E CT
Sbjct: 482 SGTWGLNCN--ESCT 494
Score = 52.0 bits (123), Expect = 3e-06
Identities = 59/201 (29%), Positives = 69/201 (34%), Gaps = 48/201 (23%)
Query: 27 VCDCNGKSRQCIFDRELHRQTG-NGFRC-LNCNDNTDGIHCEK---CKNGFYRHRERDRC 81
+C CN D + G G C L C T G++C + C NG C
Sbjct: 449 ICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSC 508
Query: 82 ------------LPCNCNSKG-SLSARCDNS---------GRCSCKPGVTGARCD-RCLP 118
LPC + G + S CD S G C C G TG RCD C P
Sbjct: 509 SCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPP 568
Query: 119 GFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDR-CRSGYYNLD 177
G C+ C C+ G P D G C C P G C R C G+Y
Sbjct: 569 G---RWGPNCS-------VSCSCENGGSCSPED-GSCECAPGFRGPLCQRICPPGFYG-- 615
Query: 178 GGNPEGCTQ-C-FCYGHSASC 196
GC Q C C S C
Sbjct: 616 ----HGCAQPCPLCVHSSRPC 632
Score = 51.6 bits (122), Expect = 4e-06
Identities = 45/151 (29%), Positives = 60/151 (39%), Gaps = 30/151 (19%)
Query: 56 CNDNTDGIHCEK-CKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARC 113
C G C++ C GFY H C C +S+ C + SG C C PG +GA C
Sbjct: 596 CAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRP-----CHHISGICECLPGFSGALC 650
Query: 114 DRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDR-CRSG 172
++ G + D C Q C C G P D G C C P G+ C + C G
Sbjct: 651 NQVCAGGYFGQD--CAQ-------LCSCANNGTCSPID-GSCQCFPGWIGKDCSQACPPG 700
Query: 173 YYNLDGGNPEGCTQCFCYGHSASCRSSAEYS 203
++ CF H+ SC + A S
Sbjct: 701 FWG---------PACF---HACSCHNGASCS 719
Score = 45.8 bits (107), Expect = 2e-04
Identities = 38/134 (28%), Positives = 52/134 (38%), Gaps = 27/134 (20%)
Query: 67 KCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDA 126
+C G+Y D C+P C + + RC + C C+PG G C +
Sbjct: 87 QCCPGYYE--SGDFCIPL-CTEE-CVHGRCVSPDTCHCEPGWGGPDC-----------SS 131
Query: 127 GCTQDQ--RLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDR-CRSGYYNLDGGNPEG 183
GC D ++C C + P G CVC G RC+ C G + +G
Sbjct: 132 GCDSDHWGPHCSNRCQCQNGALCNPI-TGACVCAAGFRGWRCEELCAPGTHG------KG 184
Query: 184 C-TQCFCYGHSASC 196
C C C H ASC
Sbjct: 185 CQLPCQC-RHGASC 197
Score = 38.1 bits (87), Expect = 0.047
Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 15/73 (20%)
Query: 552 QCKAGYF--GDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAFS- 608
QC GY+ GD P ++C C S TC C+PG+GGP+C G S
Sbjct: 87 QCCPGYYESGDFCIPLCTEECVHGRCV----------SPDTCHCEPGWGGPDCSSGCDSD 136
Query: 609 --CPACYNQVKIQ 619
P C N+ + Q
Sbjct: 137 HWGPHCSNRCQCQ 149
Score = 37.4 bits (85), Expect = 0.080
Identities = 21/63 (33%), Positives = 24/63 (38%), Gaps = 8/63 (12%)
Query: 381 QCICPVGYKGQFC-QDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPD 439
+C C G+ GQ C Q CA G +G C C CD TG CY
Sbjct: 767 KCTCRTGFTGQHCEQRCAPG-------TFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKG 819
Query: 440 IEC 442
I C
Sbjct: 820 IRC 822
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 102 bits (254), Expect = 2e-21
Identities = 61/144 (42%), Positives = 74/144 (51%), Gaps = 20/144 (13%)
Query: 21 ATSRREVCDCNGKSRQCIFDRELHRQTGN--GFRCLNCNDNTDGIHCEKCKNGFYRHRER 78
A + C CNG + C FD + +GN G C +C NT+G +C++CK GFYR R
Sbjct: 325 APNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRR 384
Query: 79 -----DRCLPCNCNSKGS--LSAR----CDNS-GRCSCKPGVTGARCDRCLPGFHMLTDA 126
D C PC+C+ GS L A CD S G C CKPGV G RCDRC+ G+ D
Sbjct: 385 PFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDY 444
Query: 127 GCTQDQRLLDSKCDCDPAGIAGPC 150
GC R D CDP I G C
Sbjct: 445 GC----RPCDCAGSCDP--ITGDC 462
Score = 89.7 bits (221), Expect = 1e-17
Identities = 60/180 (33%), Positives = 79/180 (43%), Gaps = 33/180 (18%)
Query: 463 PCHNGFSCSVMPETEEVVCNNC--PPGVTGARCELCADGYFGDPF----GEHGPVRPCQP 516
P H GF P T +V C G+ C+ CA Y P+ G+ G C+
Sbjct: 273 PVH-GFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRT 331
Query: 517 CQCNNNVDP--------SASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPA- 567
C+CN + D ASGN R G C C HNT G YC +CK G++ D P A
Sbjct: 332 CKCNGHADTCHFDVNVWEASGN--RSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAP 389
Query: 568 DKCRACNCNPMGSEPVGCR-------SDGTCVCKPGFGGPNCEH--------GAFSCPAC 612
D C+ C+C+P+GS + S+G C CKPG G C+ G + C C
Sbjct: 390 DACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPC 449
Score = 88.6 bits (218), Expect = 3e-17
Identities = 61/193 (31%), Positives = 77/193 (39%), Gaps = 55/193 (28%)
Query: 381 QCICPVGYKGQFCQDCASGY-----KRDSARLGPFGTCIPCNCQG--------------- 420
+C+C G CQ CA Y + + G C C C G
Sbjct: 292 KCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEAS 351
Query: 421 ----GGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRS----CKPCPCHNGFSCSV 472
GG CD DC E C C GFY D P S CKPC CH +V
Sbjct: 352 GNRSGGVCD----DCQHNTEGQ--YCQRCKPGFYRDLRRPFSAPDACKPCSCH-PVGSAV 404
Query: 473 MPETEEVVCN------NCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPS 526
+P C+ C PGV G RC+ C GY+G FG++G C+PC C
Sbjct: 405 LPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWG--FGDYG----CRPCDC------- 451
Query: 527 ASGNCDRLTGRCL 539
+G+CD +TG C+
Sbjct: 452 -AGSCDPITGDCI 463
Score = 44.7 bits (104), Expect = 5e-04
Identities = 24/58 (41%), Positives = 29/58 (50%), Gaps = 7/58 (12%)
Query: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPD 439
C C G G+ C C GY G +G C PC+C G+CDP TGDC S + D
Sbjct: 420 CPCKPGVAGRRCDRCMVGYWG----FGDYG-CRPCDC--AGSCDPITGDCISSHTDID 470
>gi|190014607 netrin G2 [Homo sapiens]
Length = 530
Score = 97.4 bits (241), Expect = 6e-20
Identities = 53/160 (33%), Positives = 76/160 (47%), Gaps = 21/160 (13%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR-----ERDRCL 82
C+C G S +C + L+ T C++C NT G HC+ C+ G+YR+ + + C+
Sbjct: 353 CECYGHSNRCSYIDFLNVVT-----CVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCI 407
Query: 83 PCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLLDSKC 139
CNCN GS+ RC+ +G C C+ G G +CD CLP + C DQ L +
Sbjct: 408 ECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGG 467
Query: 140 DCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGG 179
C RC C TG RC++ R + DGG
Sbjct: 468 TC--------LQNQRCACPRGYTGVRCEQPRCDPADDDGG 499
Score = 63.2 bits (152), Expect = 1e-09
Identities = 41/141 (29%), Positives = 54/141 (38%), Gaps = 29/141 (20%)
Query: 484 CPPGVTGARCELC----------ADGYFGDPFGEHGPVRPCQP------CQCNNNVDPSA 527
C TG C C A Y P HG C C+C +
Sbjct: 307 CEHNTTGPDCGKCKKNFRTRSWRAGSYLPLP---HGSPNACATAGSFGNCECYGH----- 358
Query: 528 SGNCDRL----TGRCLKCIHNTAGIYCDQCKAGYFGDPLAP-NPADKCRACNCNPMGSEP 582
S C + C+ C HNT G +C C+ GY+ + A + + C CNCN +GS
Sbjct: 359 SNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVH 418
Query: 583 VGCRSDGTCVCKPGFGGPNCE 603
C G C C+ G GP C+
Sbjct: 419 DRCNETGFCECREGAAGPKCD 439
Score = 55.8 bits (133), Expect = 2e-07
Identities = 51/195 (26%), Positives = 67/195 (34%), Gaps = 15/195 (7%)
Query: 414 IPCNCQGGGACDPDTGDCYSGDENPDIECAD---CPIGFYNDPHDPRSCKPCPCHNGFS- 469
+ C C+ PD G C P G N S C C+ +
Sbjct: 303 LQCECEHN-TTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNR 361
Query: 470 CSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASG 529
CS + V C +C G C+ C GY+ + E C C CN S
Sbjct: 362 CSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQ--IGSVHD 419
Query: 530 NCDRLTGRCLKCIHNTAGIYCDQC-KAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD 588
C+ TG C +C AG CD C Y+ PN D + C G+ C +
Sbjct: 420 RCNE-TGFC-ECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLL-CQNGGT----CLQN 472
Query: 589 GTCVCKPGFGGPNCE 603
C C G+ G CE
Sbjct: 473 QRCACPRGYTGVRCE 487
Score = 55.8 bits (133), Expect = 2e-07
Identities = 43/125 (34%), Positives = 55/125 (44%), Gaps = 16/125 (12%)
Query: 379 VEQCI-CPVGYKGQFCQDCASGYKRD-SARLGPFGTCIPCNCQGGGA----CDPDTGDCY 432
V C+ C +GQ CQ C GY R+ SA L CI CNC G+ C+ +TG C
Sbjct: 370 VVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFCE 428
Query: 433 SGDENPDIECADC-PIGFYNDPHDPRSC--KPCPCHNGFSCSVMPETEEVVCNNCPPGVT 489
+ +C DC P ++ P C C NG +C + C CP G T
Sbjct: 429 CREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC-----LQNQRC-ACPRGYT 482
Query: 490 GARCE 494
G RCE
Sbjct: 483 GVRCE 487
Score = 53.5 bits (127), Expect = 1e-06
Identities = 48/181 (26%), Positives = 65/181 (35%), Gaps = 35/181 (19%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCL----- 82
C CN + C RE +C C NT G C KCK F R
Sbjct: 287 CKCNLHANLCSM-RE------GSLQC-ECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPH 338
Query: 83 --PCNCNSKGSLSARCD---NSGRCS------------CKPGVTGARCDRCLPGFHMLTD 125
P C + GS C+ +S RCS CK G C C G++ +
Sbjct: 339 GSPNACATAGSFG-NCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYR--N 395
Query: 126 AGCTQDQRLLDSKCDCDPAG-IAGPC-DAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEG 183
D + +C+C+ G + C + G C C+ G +CD C +Y G P
Sbjct: 396 GSAELDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNV 455
Query: 184 C 184
C
Sbjct: 456 C 456
Score = 48.1 bits (113), Expect = 5e-05
Identities = 35/127 (27%), Positives = 47/127 (37%), Gaps = 23/127 (18%)
Query: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDP 143
C CN +L + + S +C C+ TG C +C F + + S C
Sbjct: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346
Query: 144 AGIAGPCD----AGRC------------VCKPAVTGERCDRCRSGYY-----NLDGGNPE 182
AG G C+ + RC CK G+ C CR GYY LD N
Sbjct: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV- 405
Query: 183 GCTQCFC 189
C +C C
Sbjct: 406 -CIECNC 411
Score = 35.0 bits (79), Expect = 0.39
Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 16/59 (27%)
Query: 154 RCVCKPAVTGERCDRCRSG----------YYNLDGGNPEGCT------QCFCYGHSASC 196
+C C+ TG C +C+ Y L G+P C C CYGHS C
Sbjct: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRC 362
>gi|164414431 netrin G1 isoform 1 [Homo sapiens]
Length = 539
Score = 95.5 bits (236), Expect = 2e-19
Identities = 56/153 (36%), Positives = 76/153 (49%), Gaps = 25/153 (16%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR-----ERDRCL 82
C+C G S +C + L N C++C NT G HCE C+ G++R+ + + C+
Sbjct: 364 CECFGHSNRCSYIDLL-----NTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCI 418
Query: 83 PCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPG--FHMLTDAGCTQ---DQRLLDS 137
C CN GS+ RC+ SG C CK G TG +CD CLPG +H GC D LL
Sbjct: 419 ECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHY----GCQPNVCDNELL-- 472
Query: 138 KCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCR 170
C G + RC+C A TG C++ R
Sbjct: 473 --HCQNGGTCH--NNVRCLCPAAYTGILCEKLR 501
Score = 75.5 bits (184), Expect = 3e-13
Identities = 51/160 (31%), Positives = 69/160 (43%), Gaps = 24/160 (15%)
Query: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQC 519
C C+ + V + ++ C C TG C C Y G P+ G + P+ P
Sbjct: 297 CKCNLHATVCVY-DNSKLTCE-CEHNTTGPDCGKCKKNYQGRPWSPGSYLPI----PKGT 350
Query: 520 NNNVDPSAS--GNCDRL-------------TGRCLKCIHNTAGIYCDQCKAGYFGDPLAP 564
N PS S GNC+ T C+ C HNT G +C+ C+ GYF + A
Sbjct: 351 ANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQ 410
Query: 565 -NPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE 603
+ + C C CNP+GS C G C CK G GP C+
Sbjct: 411 LDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCD 450
Score = 61.2 bits (147), Expect = 5e-09
Identities = 52/182 (28%), Positives = 68/182 (37%), Gaps = 36/182 (19%)
Query: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR----------- 76
C CN + C++D N C NT G C KCK +
Sbjct: 297 CKCNLHATVCVYD--------NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPK 348
Query: 77 -ERDRCLPC-----NCNSKGSLSARCD-----NSGRC-SCKPGVTGARCDRCLPGFHMLT 124
+ C+P NC G S RC N+ C SCK G C+ C G+
Sbjct: 349 GTANTCIPSISSIGNCECFGH-SNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGY--FR 405
Query: 125 DAGCTQDQRLLDSKCDCDPAG-IAGPCD-AGRCVCKPAVTGERCDRCRSGYYNLDGGNPE 182
+A D + +C C+P G I C+ +G C CK TG +CD C G G P
Sbjct: 406 NASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPN 465
Query: 183 GC 184
C
Sbjct: 466 VC 467
Score = 48.1 bits (113), Expect = 5e-05
Identities = 50/211 (23%), Positives = 66/211 (31%), Gaps = 61/211 (28%)
Query: 428 TGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCP------CHNGFS------------ 469
T +C PD C C + P P S P P C S
Sbjct: 314 TCECEHNTTGPD--CGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSN 371
Query: 470 -CSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSAS 528
CS + V+C +C G CELC GYF + AS
Sbjct: 372 RCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRN-----------------------AS 408
Query: 529 GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRAC--------NCNP--M 578
D C++C N G D+C F + KC C C P
Sbjct: 409 AQLDD-ENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVC 467
Query: 579 GSEPVGCRSDGT------CVCKPGFGGPNCE 603
+E + C++ GT C+C + G CE
Sbjct: 468 DNELLHCQNGGTCHNNVRCLCPAAYTGILCE 498
Score = 43.9 bits (102), Expect = 9e-04
Identities = 43/144 (29%), Positives = 57/144 (39%), Gaps = 30/144 (20%)
Query: 384 CPVGYKGQFCQDCASGYKRD-SARLGPFGTCIPC----------NCQGGGACDPDTGDCY 432
C +GQ C+ C GY R+ SA+L CI C C G G C +C
Sbjct: 387 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFC-----ECK 441
Query: 433 SGDENPDIECADC-PIGFYNDPHDPRSC--KPCPCHNGFSCSVMPETEEVVCNNCPPGVT 489
+G P +C +C P ++ P C + C NG +C V C CP T
Sbjct: 442 TGTTGP--KCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCH-----NNVRC-LCPAAYT 493
Query: 490 GARCE--LCAD-GYFGDPFGEHGP 510
G CE C + G G G+ P
Sbjct: 494 GILCEKLRCEEAGSCGSDSGQGAP 517
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,028,479
Number of Sequences: 37866
Number of extensions: 2349349
Number of successful extensions: 15126
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 153
Number of HSP's successfully gapped in prelim test: 653
Number of HSP's that attempted gapping in prelim test: 7875
Number of HSP's gapped (non-prelim): 3796
length of query: 1111
length of database: 18,247,518
effective HSP length: 113
effective length of query: 998
effective length of database: 13,968,660
effective search space: 13940722680
effective search space used: 13940722680
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.