BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] (1816 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 3655 0.0 gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 3655 0.0 gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 3648 0.0 gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 831 0.0 gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 804 0.0 gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 799 0.0 gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 755 0.0 gi|21264602 laminin alpha 5 [Homo sapiens] 687 0.0 gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 421 e-117 gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 419 e-116 gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 394 e-109 gi|167614504 laminin, beta 1 precursor [Homo sapiens] 171 5e-42 gi|143770880 laminin, beta 4 [Homo sapiens] 164 6e-40 gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 159 3e-38 gi|119703755 laminin, beta 2 precursor [Homo sapiens] 159 3e-38 gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 145 3e-34 gi|157419130 laminin, alpha 4 isoform 3 precursor [Homo sapiens] 135 3e-31 gi|157419128 laminin, alpha 4 isoform 3 precursor [Homo sapiens] 135 3e-31 gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 132 4e-30 gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 131 7e-30 gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 129 2e-29 gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 128 6e-29 gi|219842266 usherin isoform B [Homo sapiens] 106 2e-22 gi|93204871 netrin 4 [Homo sapiens] 102 3e-21 gi|62868217 laminin, beta 3 precursor [Homo sapiens] 100 2e-20 gi|62868215 laminin, beta 3 precursor [Homo sapiens] 100 2e-20 gi|189083719 laminin, beta 3 precursor [Homo sapiens] 100 2e-20 gi|219842259 usherin isoform A [Homo sapiens] 92 4e-18 gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens] 87 1e-16 gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens] 87 1e-16 >gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] Length = 1816 Score = 3655 bits (9478), Expect = 0.0 Identities = 1816/1816 (100%), Positives = 1816/1816 (100%) Query: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL Sbjct: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60 Query: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD Sbjct: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120 Query: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI Sbjct: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180 Query: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV Sbjct: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240 Query: 241 CNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAA 300 CNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAA Sbjct: 241 CNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAA 300 Query: 301 HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG 360 HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG Sbjct: 301 HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG 360 Query: 361 QLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKML 420 QLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKML Sbjct: 361 QLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKML 420 Query: 421 EEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSD 480 EEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSD Sbjct: 421 EEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSD 480 Query: 481 LQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT 540 LQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT Sbjct: 481 LQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT 540 Query: 541 LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK 600 LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK Sbjct: 541 LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK 600 Query: 601 LHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD 660 LHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD Sbjct: 601 LHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD 660 Query: 661 ESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDA 720 ESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDA Sbjct: 661 ESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDA 720 Query: 721 QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN 780 QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN Sbjct: 721 QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN 780 Query: 781 LTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVH 840 LTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVH Sbjct: 781 LTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVH 840 Query: 841 SRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYV 900 SRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYV Sbjct: 841 SRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYV 900 Query: 901 YNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS 960 YNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS Sbjct: 901 YNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS 960 Query: 961 GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM 1020 GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM Sbjct: 961 GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM 1020 Query: 1021 DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL 1080 DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL Sbjct: 1021 DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL 1080 Query: 1081 ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDK 1140 ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDK Sbjct: 1081 ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDK 1140 Query: 1141 KMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQF 1200 KMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQF Sbjct: 1141 KMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQF 1200 Query: 1201 QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ 1260 QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ Sbjct: 1201 QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ 1260 Query: 1261 PNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELI 1320 PNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELI Sbjct: 1261 PNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELI 1320 Query: 1321 VDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVED 1380 VDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVED Sbjct: 1321 VDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVED 1380 Query: 1381 FQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLP 1440 FQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLP Sbjct: 1381 FQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLP 1440 Query: 1441 ERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGM 1500 ERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGM Sbjct: 1441 ERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGM 1500 Query: 1501 IFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRL 1560 IFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRL Sbjct: 1501 IFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRL 1560 Query: 1561 VIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGAS 1620 VIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGAS Sbjct: 1561 VIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGAS 1620 Query: 1621 ITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH 1680 ITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH Sbjct: 1621 ITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH 1680 Query: 1681 GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDV 1740 GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDV Sbjct: 1681 GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDV 1740 Query: 1741 DSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1800 DSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK Sbjct: 1741 DSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1800 Query: 1801 AALVSGAVSINSCPAA 1816 AALVSGAVSINSCPAA Sbjct: 1801 AALVSGAVSINSCPAA 1816 >gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] Length = 1816 Score = 3655 bits (9478), Expect = 0.0 Identities = 1816/1816 (100%), Positives = 1816/1816 (100%) Query: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL Sbjct: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60 Query: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD Sbjct: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120 Query: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI Sbjct: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180 Query: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV Sbjct: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240 Query: 241 CNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAA 300 CNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAA Sbjct: 241 CNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAA 300 Query: 301 HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG 360 HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG Sbjct: 301 HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG 360 Query: 361 QLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKML 420 QLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKML Sbjct: 361 QLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKML 420 Query: 421 EEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSD 480 EEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSD Sbjct: 421 EEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSD 480 Query: 481 LQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT 540 LQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT Sbjct: 481 LQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT 540 Query: 541 LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK 600 LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK Sbjct: 541 LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK 600 Query: 601 LHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD 660 LHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD Sbjct: 601 LHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD 660 Query: 661 ESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDA 720 ESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDA Sbjct: 661 ESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDA 720 Query: 721 QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN 780 QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN Sbjct: 721 QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN 780 Query: 781 LTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVH 840 LTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVH Sbjct: 781 LTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVH 840 Query: 841 SRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYV 900 SRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYV Sbjct: 841 SRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYV 900 Query: 901 YNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS 960 YNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS Sbjct: 901 YNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS 960 Query: 961 GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM 1020 GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM Sbjct: 961 GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM 1020 Query: 1021 DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL 1080 DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL Sbjct: 1021 DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL 1080 Query: 1081 ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDK 1140 ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDK Sbjct: 1081 ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDK 1140 Query: 1141 KMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQF 1200 KMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQF Sbjct: 1141 KMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQF 1200 Query: 1201 QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ 1260 QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ Sbjct: 1201 QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ 1260 Query: 1261 PNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELI 1320 PNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELI Sbjct: 1261 PNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELI 1320 Query: 1321 VDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVED 1380 VDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVED Sbjct: 1321 VDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVED 1380 Query: 1381 FQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLP 1440 FQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLP Sbjct: 1381 FQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLP 1440 Query: 1441 ERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGM 1500 ERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGM Sbjct: 1441 ERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGM 1500 Query: 1501 IFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRL 1560 IFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRL Sbjct: 1501 IFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRL 1560 Query: 1561 VIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGAS 1620 VIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGAS Sbjct: 1561 VIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGAS 1620 Query: 1621 ITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH 1680 ITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH Sbjct: 1621 ITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH 1680 Query: 1681 GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDV 1740 GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDV Sbjct: 1681 GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDV 1740 Query: 1741 DSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1800 DSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK Sbjct: 1741 DSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1800 Query: 1801 AALVSGAVSINSCPAA 1816 AALVSGAVSINSCPAA Sbjct: 1801 AALVSGAVSINSCPAA 1816 >gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] Length = 1823 Score = 3648 bits (9460), Expect = 0.0 Identities = 1816/1823 (99%), Positives = 1816/1823 (99%), Gaps = 7/1823 (0%) Query: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL Sbjct: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60 Query: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD Sbjct: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120 Query: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI Sbjct: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180 Query: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV Sbjct: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240 Query: 241 CNCGGGPCDSVTGECLEEGFEPPTG-------CDKCVWDLTDALRLAALSIEEGKSGVLS 293 CNCGGGPCDSVTGECLEEGFEPPTG CDKCVWDLTDALRLAALSIEEGKSGVLS Sbjct: 241 CNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDALRLAALSIEEGKSGVLS 300 Query: 294 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE 353 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE Sbjct: 301 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE 360 Query: 354 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL 413 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL Sbjct: 361 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL 420 Query: 414 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD 473 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD Sbjct: 421 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD 480 Query: 474 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS 533 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS Sbjct: 481 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS 540 Query: 534 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 593 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE Sbjct: 541 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 600 Query: 594 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT 653 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT Sbjct: 601 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT 660 Query: 654 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ 713 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ Sbjct: 661 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ 720 Query: 714 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS 773 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS Sbjct: 721 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS 780 Query: 774 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG 833 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG Sbjct: 781 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG 840 Query: 834 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK 893 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK Sbjct: 841 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK 900 Query: 894 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF 953 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF Sbjct: 901 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF 960 Query: 954 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN 1013 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN Sbjct: 961 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN 1020 Query: 1014 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR 1073 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR Sbjct: 1021 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR 1080 Query: 1074 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS 1133 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS Sbjct: 1081 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS 1140 Query: 1134 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG 1193 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG Sbjct: 1141 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG 1200 Query: 1194 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG 1253 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG Sbjct: 1201 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG 1260 Query: 1254 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS 1313 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS Sbjct: 1261 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS 1320 Query: 1314 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD 1373 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD Sbjct: 1321 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD 1380 Query: 1374 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD 1433 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD Sbjct: 1381 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD 1440 Query: 1434 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR 1493 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR Sbjct: 1441 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR 1500 Query: 1494 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR 1553 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR Sbjct: 1501 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR 1560 Query: 1554 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN 1613 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN Sbjct: 1561 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN 1620 Query: 1614 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS 1673 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS Sbjct: 1621 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS 1680 Query: 1674 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS 1733 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS Sbjct: 1681 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS 1740 Query: 1734 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG 1793 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG Sbjct: 1741 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG 1800 Query: 1794 HPVSFSKAALVSGAVSINSCPAA 1816 HPVSFSKAALVSGAVSINSCPAA Sbjct: 1801 HPVSFSKAALVSGAVSINSCPAA 1823 >gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] Length = 3333 Score = 831 bits (2147), Expect = 0.0 Identities = 559/1815 (30%), Positives = 892/1815 (49%), Gaps = 155/1815 (8%) Query: 40 SAVGRQDPPETSEPRVALG----RLPPA-----AEKCNAGFFHT----LSGECVPCDCNG 86 S VG ++ +T R+AL PPA + C+ G++ +G CVPC+CNG Sbjct: 1632 SEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNG 1691 Query: 87 NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESC 146 +SN+C DGSG CV+CQ NT GEHCE+C +GY G+++ G+ C+ CPC PH +FA C Sbjct: 1692 HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS---CRACPC--PHTNSFATGC 1746 Query: 147 YRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVT 206 G VRC C Y G CERCAPGY+GNP G +C+ C C+ N C +T Sbjct: 1747 VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLT 1802 Query: 207 GQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGC 266 G C N P DS E ++ C Sbjct: 1803 GDCIN---------------------------------QEPKDSSPAEECDD-------C 1822 Query: 267 DKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYA 326 D CV L + L + KS + +S+ A + + L+ +L + + Sbjct: 1823 DSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAIS 1882 Query: 327 LRKIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRD 386 +I E + L + E L EK SRK Q + N+ ++ + A ++ Sbjct: 1883 NHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN-------NNVNRATQSAKELDV 1935 Query: 387 KIQEINNKMLYY--------GEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDE 438 KI+ + + GE + + + S + AQ+M+ E+R+R + L + Sbjct: 1936 KIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRN---FGKHLREA 1992 Query: 439 EAD--EAYELLSQAESWQRLH-NETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDA 495 EAD E+ LL++ +WQ+ H E L + + L++Y AKLSDL+ L +A + A Sbjct: 1993 EADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQA 2052 Query: 496 EDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIY 555 +N+ ++Q + + L+T+ SL + L ++ K + Sbjct: 2053 NGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLA 2112 Query: 556 AEIDGAKSELQVKLSNLSNLS--HDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKA 613 A ++ A+ EL K+ LS + LV+EA HA+ LQ+ A +L ++ + LV+ A Sbjct: 2113 ASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCA 2172 Query: 614 LDASNVYENIVNYVSEANETAEFALNTTDRIYDAV--SGIDTQIIYHKDESENLLNQARE 671 +DA+ YENI+N + A + A A + ++ V + + S+ LLN+A+ Sbjct: 2173 VDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKM 2232 Query: 672 LQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLIT 731 Q K + A+ + + + +K + T L+ L +RGD + ++ + Sbjct: 2233 TQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMV 2292 Query: 732 EEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQ 791 +AN T EV P+ ++ + + A+ A ++V LT +P L + Sbjct: 2293 RKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRK 2352 Query: 792 LRTVEQK-RPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKA 850 + ++ Q+ P N+S ++ RIRELI Q R ASK+ V M F+G+S VEV ++DLK Sbjct: 2353 IESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKG 2412 Query: 851 FTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEI 910 +TSLSL+++ P R E T + F++YLG+K+A ++Y+G+A+ + L VYNLG ++ E+ Sbjct: 2413 YTSLSLFLQRPNSR-ENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAEL 2471 Query: 911 PLDSKPVSS--WPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDL 968 +D S A VK +R+ + ++ T + SS E + + ++LL+L Sbjct: 2472 QVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNL 2531 Query: 969 DPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPC 1028 DPE+ VFYVGG P +FKLP+ L+ P + GC+EL LN +V+SLYNFK +N++ + PC Sbjct: 2532 DPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPC 2591 Query: 1029 ARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGS 1088 R K + +F+G+GYA V + F ++T D GL+ NG Sbjct: 2592 RRRK-----EESDKNYFEGTGYARV----PTQPHAPIPTFGQTIQTTVDRGLLFFAENGD 2642 Query: 1089 MFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQ-----INDAKYHEISI-IYHNDKKM 1142 F L + +G L V Y L L K + IN+ + H I I I K+M Sbjct: 2643 RFISLNIEDGKLMVRY---------KLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRM 2693 Query: 1143 ILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQK 1202 + VD ++ +D E F+ Y+GG P I + + FRGCMK K Sbjct: 2694 WINVDVQNT-IIDGE--VFDFSTYYLGGIPIAIRERFNISTPA-----FRGCMKNL---K 2742 Query: 1203 KDFNLLEQTETLGVGYGCPEDSLISRRAYFN-GQSFIASIQKISFFDGFEGGFNFRTLQP 1261 K ++ +T+GV C ED + R A F+ G + + D + F F+T QP Sbjct: 2743 KTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQP 2802 Query: 1262 NGLLFYYASGSDVFSISLDNGTVIMDV--KGIKVQSVDKQYNDGLSHFVISSVSPTRYEL 1319 +G+L + + + ++L++G + + G + + Y DGL H+V + L Sbjct: 2803 SGILLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRL 2862 Query: 1320 IVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVE 1379 ++D + + +++ +S + GGS NF GCISN + R+ EV Sbjct: 2863 LIDDQLLRNSK----RLKHISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEVL 2911 Query: 1380 DFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKL 1439 D + K SL C + P +L K +K K + + +D P P ++K+ Sbjct: 2912 DLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKV 2969 Query: 1440 PERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHG 1499 + C +A A Q+G S F+ + +SQF++ ++T SS G Sbjct: 2970 WQ------DACSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRG 3023 Query: 1500 MIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGR 1559 ++F+ +N FM L+L+ GRLV+ KKL+I+S+EK NDG WH V+F + GR Sbjct: 3024 LVFHTG--TKNSFMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGR 3081 Query: 1560 LVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGA 1619 LV+DGLR E SL P +T I+ P+YLG GK K++ N SF GCL N QL+ Sbjct: 3082 LVVDGLRAREGSL-PGNSTISIRAPVYLGSPPSGKP-KSLPTN---SFVGCLKNFQLDSK 3136 Query: 1620 SITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLV 1679 + + S +F V+ C GP+E G YFS EGG+VVL S +G +F++ F +RPRS +G L+ Sbjct: 3137 PLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILI 3196 Query: 1680 HGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLD 1739 H S G++L V+++ G+V +++G STSVTPKQSLCDG+WH + V +++ L+ Sbjct: 3197 HIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLE 3256 Query: 1740 VDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFS 1799 +D++ ++ G + P +EP+ +GG P +L T R+ K F GC+R+ ++ PV + Sbjct: 3257 LDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVT 3316 Query: 1800 KAALVSGAVSINSCP 1814 +A V G VS+N CP Sbjct: 3317 EALEVQGPVSLNGCP 3331 Score = 107 bits (268), Expect = 8e-23 Identities = 73/237 (30%), Positives = 99/237 (41%), Gaps = 58/237 (24%) Query: 76 SGECVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGY 117 S EC C+C+G+++ C G G C++CQ NT G +CE+C GY Sbjct: 350 SHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGY 409 Query: 118 I---GDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174 G + AP C PC C H A+ C + G+ RC C N+ G NCE+CA GYY Sbjct: 410 YRPYGVPV-DAPDGCIPCSCDPEH----ADGC--EQGSGRCHCKPNFHGDNCEKCAIGYY 462 Query: 175 GNPLL----------------IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTG 218 P + K CDC+ ++ E CD G+C C G Sbjct: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLE---GVLPEICD-AHGRCL-CRPGVEG 517 Query: 219 FKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGCDKCV 270 +C+ C G+Y C C C PC SVTG+C CD+C+ Sbjct: 518 PRCDTCRSGFYS----FPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCL 570 Score = 80.9 bits (198), Expect = 1e-14 Identities = 74/246 (30%), Positives = 100/246 (40%), Gaps = 66/246 (26%) Query: 74 TLSGECVPCDCNGNSNECLDGSG---YCVHCQRNTTGEHCEKCLDGYIGDSIRGA----P 126 ++ G+CV CNG++ C + + CQ +T GE C++C GY R A Sbjct: 294 SIGGQCV---CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQS 350 Query: 127 QFCQPCPCPLPHLANFAESCY-----------------RKNGAVRCICNENYAGPNCERC 169 C+ C C A +CY G V C N AG NCE+C Sbjct: 351 HECEACNC-----HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQC 405 Query: 170 APGY---YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226 A GY YG P+ C C C DP + C++ +G+C +C N G CE+CA Sbjct: 406 AKGYYRPYGVPVDAPDGCIPCSC----DPEHA-DGCEQGSGRC-HCKPNFHGDNCEKCAI 459 Query: 227 GYY-----------------GDARIAKNCAVCNC---GGGP--CDSVTGECL-EEGFEPP 263 GYY + +A + C+C G P CD+ G CL G E P Sbjct: 460 GYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA-HGRCLCRPGVEGP 518 Query: 264 TGCDKC 269 CD C Sbjct: 519 R-CDTC 523 Score = 71.2 bits (173), Expect = 8e-12 Identities = 70/266 (26%), Positives = 96/266 (36%), Gaps = 30/266 (11%) Query: 18 SAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSG 77 ++A S A A P + + A G PE + + +C G H Sbjct: 1250 NSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATG--HYGFP 1307 Query: 78 ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKC-LDGYIGDSIRGAPQFCQPCPCPL 136 C PC C C + +G C C T CE C + + G C+ C C Sbjct: 1308 RCKPCSCGRRL--CEEMTGQC-RCPPRTVRPQCEVCETHSFSFHPMAG----CEGCNCSR 1360 Query: 137 PHLANFA-ESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCS-GNSD 194 A C R +G +C C G C+RCA G+Y P C C+C+ ++ Sbjct: 1361 RGTIEAAMPECDRDSG--QCRCKPRITGRQCDRCASGFYRFP-----ECVPCNCNRDGTE 1413 Query: 195 PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG-YYGDARIAKNCAVCNCGGGPCDSVTG 253 P + CD TG C C N G +C C G ++ D K C C C G V Sbjct: 1414 PGV----CDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKGCTSCFCFG-----VNN 1463 Query: 254 ECLEEGFEPPTGCDKCVWDLTDALRL 279 +C D W L A R+ Sbjct: 1464 QCHSSHKRRTKFVDMLGWHLETADRV 1489 Score = 70.1 bits (170), Expect = 2e-11 Identities = 57/210 (27%), Positives = 73/210 (34%), Gaps = 59/210 (28%) Query: 105 TTGEHCEKCLDGYIGDSIRGA-PQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAG 163 T C+ + +GA P C P PH C + G +C C N G Sbjct: 1243 TASRFCKNSARSLVAFYHKGALPCECHPTGATGPH-------CSPEGG--QCPCQPNVIG 1293 Query: 164 PNCERCAPGYYG----NPLLIG-----------------------------------STC 184 C RCA G+YG P G + C Sbjct: 1294 RQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGC 1353 Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244 + C+CS +CD +GQCR C TG +C+RCA G+Y C CNC Sbjct: 1354 EGCNCSRRGTIEAAMPECDRDSGQCR-CKPRITGRQCDRCASGFYR----FPECVPCNCN 1408 Query: 245 -----GGPCDSVTGECLEEGFEPPTGCDKC 269 G CD TG CL + T C+ C Sbjct: 1409 RDGTEPGVCDPGTGACLCKENVEGTECNVC 1438 Score = 63.5 bits (153), Expect = 2e-09 Identities = 52/210 (24%), Positives = 77/210 (36%), Gaps = 24/210 (11%) Query: 62 PAAEKCNAGFFHTLSGECVPCDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDG-YIG 119 P + C +GF+ + C G+ C +G C C+ TG+ C++CL G Y Sbjct: 518 PRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDF 576 Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179 +G+ C P +L C C + GP C RC Y+ Sbjct: 577 PHCQGSSSACDPAGTINSNLGY-------------CQCKLHVEGPTCSRCKLLYWNLDKE 623 Query: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCA 239 S C +C C + E C + G C +C + G C+ C GY+ + Sbjct: 624 NPSGCSECKCHKAGTVSGTGE-CRQGDGDC-HCKSHVGGDSCDTCEDGYFA----LEKSN 677 Query: 240 VCNCGGGPCDSVTGECLEEGFEPPTGCDKC 269 C G CD G L P+G +C Sbjct: 678 YFGCQGCQCD--IGGALSSMCSGPSGVCQC 705 Score = 51.6 bits (122), Expect = 7e-06 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 13/102 (12%) Query: 79 CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF-CQPC 132 C C C+ + EC G G C HC+ + G+ C+ C DGY ++ + F CQ C Sbjct: 628 CSECKCHKAGTVSGTGECRQGDGDC-HCKSHVGGDSCDTCEDGYF--ALEKSNYFGCQGC 684 Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174 C + + C +G C C E+ G C+R YY Sbjct: 685 QCDIG--GALSSMCSGPSGV--CQCREHVVGKVCQRPENNYY 722 >gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] Length = 3277 Score = 804 bits (2076), Expect = 0.0 Identities = 547/1805 (30%), Positives = 870/1805 (48%), Gaps = 191/1805 (10%) Query: 40 SAVGRQDPPETSEPRVALG----RLPPA-----AEKCNAGFFHT----LSGECVPCDCNG 86 S VG ++ +T R+AL PPA + C+ G++ +G CVPC+CNG Sbjct: 1632 SEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNG 1691 Query: 87 NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESC 146 +SN+C DGSG CV+CQ NT GEHCE+C +GY G+++ G+ C+ CPC PH +FA C Sbjct: 1692 HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS---CRACPC--PHTNSFATGC 1746 Query: 147 YRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVT 206 G VRC C Y G CERCAPGY+GNP G +C+ C C+ N C +T Sbjct: 1747 VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLT 1802 Query: 207 GQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGC 266 G C N P DS E ++ C Sbjct: 1803 GDCIN---------------------------------QEPKDSSPAEECDD-------C 1822 Query: 267 DKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYA 326 D CV L + L + KS + +S+ A + + L+ +L + + Sbjct: 1823 DSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAIS 1882 Query: 327 LRKIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRD 386 +I E + L + E L EK SRK Q + + +N A+Q Sbjct: 1883 NHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN----NNVNRATQ---------- 1928 Query: 387 KIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYEL 446 S KE+ K+ + ++ + + Sbjct: 1929 ------------------SAKELDVKI---KNVIRNV---------------------HM 1946 Query: 447 LSQAESWQRLH-NETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAAR 505 L++ +WQ+ H E L + + L++Y AKLSDL+ L +A + A +N+ Sbjct: 1947 LNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERA 2006 Query: 506 QRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSEL 565 ++Q + + L+T+ SL + L ++ K + A ++ A+ EL Sbjct: 2007 LGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQEL 2066 Query: 566 QVKLSNLSNLS--HDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENI 623 K+ LS + LV+EA HA+ LQ+ A +L ++ + LV+ A+DA+ YENI Sbjct: 2067 SDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENI 2126 Query: 624 VNYVSEANETAEFALNTTDRIYDAV--SGIDTQIIYHKDESENLLNQARELQAKAESSSD 681 +N + A + A A + ++ V + + S+ LLN+A+ Q K + Sbjct: 2127 LNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVS 2186 Query: 682 EAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEV 741 A+ + + + +K + T L+ L +RGD + ++ + +AN T EV Sbjct: 2187 PALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEV 2246 Query: 742 QQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQK-RP 800 P+ ++ + + A+ A ++V LT +P L ++ ++ Q+ P Sbjct: 2247 LDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLP 2306 Query: 801 ASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKP 860 N+S ++ RIRELI Q R ASK+ V M F+G+S VEV ++DLK +TSLSL+++ Sbjct: 2307 LGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQR 2366 Query: 861 PVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSS- 919 P R E T + F++YLG+K+A ++Y+G+A+ + L VYNLG ++ E+ +D S Sbjct: 2367 PNSR-ENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSE 2425 Query: 920 -WPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVG 978 A VK +R+ + ++ T + SS E + + ++LL+LDPE+ VFYVG Sbjct: 2426 TKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVG 2485 Query: 979 GVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQS 1038 G P +FKLP+ L+ P + GC+EL LN +V+SLYNFK +N++ + PC R K Sbjct: 2486 GYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRK-----E 2540 Query: 1039 RAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNG 1098 + +F+G+GYA V + F ++T D GL+ NG F L + +G Sbjct: 2541 ESDKNYFEGTGYARV----PTQPHAPIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDG 2596 Query: 1099 YLHVFYDFGFSGGPVHLEDTLKKAQ-----INDAKYHEISI-IYHNDKKMILVVDRRHVK 1152 L V Y L L K + IN+ + H I I I K+M + VD ++ Sbjct: 2597 KLMVRY---------KLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNT- 2646 Query: 1153 SMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTE 1212 +D E F+ Y+GG P I + + FRGCMK KK ++ + Sbjct: 2647 IIDGE--VFDFSTYYLGGIPIAIRERFNISTPA-----FRGCMKNL---KKTSGVVRLND 2696 Query: 1213 TLGVGYGCPEDSLISRRAYFN-GQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASG 1271 T+GV C ED + R A F+ G + + D + F F+T QP+G+L + + Sbjct: 2697 TVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTW 2756 Query: 1272 SDVFSISLDNGTVIMDV--KGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSK 1329 + ++L++G + + G + + Y DGL H+V + L++D + + Sbjct: 2757 TRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNS 2816 Query: 1330 NPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVH 1389 +++ +S + GGS NF GCISN + R+ EV D + K Sbjct: 2817 K----RLKHISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEVLDLTSNSLKRD 2865 Query: 1390 TSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSH 1449 SL C + P +L K +K K + + +D P P ++K+ + Sbjct: 2866 VSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKVWQ------DA 2917 Query: 1450 CHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEE 1509 C +A A Q+G S F+ + +SQF++ ++T SS G++F+ + Sbjct: 2918 CSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTG--TK 2975 Query: 1510 NDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLE 1569 N FM L+L+ GRLV+ KKL+I+S+EK NDG WH V+F + GRLV+DGLR E Sbjct: 2976 NSFMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRARE 3035 Query: 1570 ESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFS 1629 SL P +T I+ P+YLG GK K++ N SF GCL N QL+ + + S +F Sbjct: 3036 GSL-PGNSTISIRAPVYLGSPPSGKP-KSLPTN---SFVGCLKNFQLDSKPLYTPSSSFG 3090 Query: 1630 VTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYL 1689 V+ C GP+E G YFS EGG+VVL S +G +F++ F +RPRS +G L+H S G++L Sbjct: 3091 VSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHL 3150 Query: 1690 NVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVG 1749 V+++ G+V +++G STSVTPKQSLCDG+WH + V +++ L++D++ ++ G Sbjct: 3151 CVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAG 3210 Query: 1750 PLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVS 1809 + P +EP+ +GG P +L T R+ K F GC+R+ ++ PV ++A V G VS Sbjct: 3211 QIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVS 3270 Query: 1810 INSCP 1814 +N CP Sbjct: 3271 LNGCP 3275 Score = 107 bits (268), Expect = 8e-23 Identities = 73/237 (30%), Positives = 99/237 (41%), Gaps = 58/237 (24%) Query: 76 SGECVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGY 117 S EC C+C+G+++ C G G C++CQ NT G +CE+C GY Sbjct: 350 SHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGY 409 Query: 118 I---GDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174 G + AP C PC C H A+ C + G+ RC C N+ G NCE+CA GYY Sbjct: 410 YRPYGVPV-DAPDGCIPCSCDPEH----ADGC--EQGSGRCHCKPNFHGDNCEKCAIGYY 462 Query: 175 GNPLL----------------IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTG 218 P + K CDC+ ++ E CD G+C C G Sbjct: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLE---GVLPEICD-AHGRCL-CRPGVEG 517 Query: 219 FKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGCDKCV 270 +C+ C G+Y C C C PC SVTG+C CD+C+ Sbjct: 518 PRCDTCRSGFYS----FPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCL 570 Score = 80.9 bits (198), Expect = 1e-14 Identities = 74/246 (30%), Positives = 100/246 (40%), Gaps = 66/246 (26%) Query: 74 TLSGECVPCDCNGNSNECLDGSG---YCVHCQRNTTGEHCEKCLDGYIGDSIRGA----P 126 ++ G+CV CNG++ C + + CQ +T GE C++C GY R A Sbjct: 294 SIGGQCV---CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQS 350 Query: 127 QFCQPCPCPLPHLANFAESCY-----------------RKNGAVRCICNENYAGPNCERC 169 C+ C C A +CY G V C N AG NCE+C Sbjct: 351 HECEACNC-----HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQC 405 Query: 170 APGY---YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226 A GY YG P+ C C C DP + C++ +G+C +C N G CE+CA Sbjct: 406 AKGYYRPYGVPVDAPDGCIPCSC----DPEHA-DGCEQGSGRC-HCKPNFHGDNCEKCAI 459 Query: 227 GYY-----------------GDARIAKNCAVCNC---GGGP--CDSVTGECL-EEGFEPP 263 GYY + +A + C+C G P CD+ G CL G E P Sbjct: 460 GYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA-HGRCLCRPGVEGP 518 Query: 264 TGCDKC 269 CD C Sbjct: 519 R-CDTC 523 Score = 71.2 bits (173), Expect = 8e-12 Identities = 70/266 (26%), Positives = 96/266 (36%), Gaps = 30/266 (11%) Query: 18 SAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSG 77 ++A S A A P + + A G PE + + +C G H Sbjct: 1250 NSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATG--HYGFP 1307 Query: 78 ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKC-LDGYIGDSIRGAPQFCQPCPCPL 136 C PC C C + +G C C T CE C + + G C+ C C Sbjct: 1308 RCKPCSCGRRL--CEEMTGQC-RCPPRTVRPQCEVCETHSFSFHPMAG----CEGCNCSR 1360 Query: 137 PHLANFA-ESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCS-GNSD 194 A C R +G +C C G C+RCA G+Y P C C+C+ ++ Sbjct: 1361 RGTIEAAMPECDRDSG--QCRCKPRITGRQCDRCASGFYRFP-----ECVPCNCNRDGTE 1413 Query: 195 PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG-YYGDARIAKNCAVCNCGGGPCDSVTG 253 P + CD TG C C N G +C C G ++ D K C C C G V Sbjct: 1414 PGV----CDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKGCTSCFCFG-----VNN 1463 Query: 254 ECLEEGFEPPTGCDKCVWDLTDALRL 279 +C D W L A R+ Sbjct: 1464 QCHSSHKRRTKFVDMLGWHLETADRV 1489 Score = 70.1 bits (170), Expect = 2e-11 Identities = 57/210 (27%), Positives = 73/210 (34%), Gaps = 59/210 (28%) Query: 105 TTGEHCEKCLDGYIGDSIRGA-PQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAG 163 T C+ + +GA P C P PH C + G +C C N G Sbjct: 1243 TASRFCKNSARSLVAFYHKGALPCECHPTGATGPH-------CSPEGG--QCPCQPNVIG 1293 Query: 164 PNCERCAPGYYG----NPLLIG-----------------------------------STC 184 C RCA G+YG P G + C Sbjct: 1294 RQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGC 1353 Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244 + C+CS +CD +GQCR C TG +C+RCA G+Y C CNC Sbjct: 1354 EGCNCSRRGTIEAAMPECDRDSGQCR-CKPRITGRQCDRCASGFYR----FPECVPCNCN 1408 Query: 245 -----GGPCDSVTGECLEEGFEPPTGCDKC 269 G CD TG CL + T C+ C Sbjct: 1409 RDGTEPGVCDPGTGACLCKENVEGTECNVC 1438 Score = 63.5 bits (153), Expect = 2e-09 Identities = 52/210 (24%), Positives = 77/210 (36%), Gaps = 24/210 (11%) Query: 62 PAAEKCNAGFFHTLSGECVPCDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDG-YIG 119 P + C +GF+ + C G+ C +G C C+ TG+ C++CL G Y Sbjct: 518 PRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDF 576 Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179 +G+ C P +L C C + GP C RC Y+ Sbjct: 577 PHCQGSSSACDPAGTINSNLGY-------------CQCKLHVEGPTCSRCKLLYWNLDKE 623 Query: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCA 239 S C +C C + E C + G C +C + G C+ C GY+ + Sbjct: 624 NPSGCSECKCHKAGTVSGTGE-CRQGDGDC-HCKSHVGGDSCDTCEDGYFA----LEKSN 677 Query: 240 VCNCGGGPCDSVTGECLEEGFEPPTGCDKC 269 C G CD G L P+G +C Sbjct: 678 YFGCQGCQCD--IGGALSSMCSGPSGVCQC 705 Score = 51.6 bits (122), Expect = 7e-06 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 13/102 (12%) Query: 79 CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF-CQPC 132 C C C+ + EC G G C HC+ + G+ C+ C DGY ++ + F CQ C Sbjct: 628 CSECKCHKAGTVSGTGECRQGDGDC-HCKSHVGGDSCDTCEDGYF--ALEKSNYFGCQGC 684 Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174 C + + C +G C C E+ G C+R YY Sbjct: 685 QCDIG--GALSSMCSGPSGV--CQCREHVVGKVCQRPENNYY 722 >gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] Length = 1668 Score = 799 bits (2063), Expect = 0.0 Identities = 541/1789 (30%), Positives = 864/1789 (48%), Gaps = 183/1789 (10%) Query: 47 PPETSEPRVALGRLPPAAEKCNAGFFHT----LSGECVPCDCNGNSNECLDGSGYCVHCQ 102 PP S+ + + P+ + C+ G++ +G CVPC+CNG+SN+C DGSG CV+CQ Sbjct: 40 PPGQSQLQASYVEFRPS-QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQ 98 Query: 103 RNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYA 162 NT GEHCE+C +GY G+++ G+ C+ CPC PH +FA C G VRC C Y Sbjct: 99 HNTAGEHCERCQEGYYGNAVHGS---CRACPC--PHTNSFATGCVVNGGDVRCSCKAGYT 153 Query: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCE 222 G CERCAPGY+GNP G +C+ C C+ N C +TG C N Sbjct: 154 GTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLTGDCIN----------- 198 Query: 223 RCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAAL 282 P DS E ++ CD CV L + L Sbjct: 199 ----------------------QEPKDSSPAEECDD-------CDSCVMTLLNDLATMGE 229 Query: 283 SIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSL 342 + KS + +S+ A + + L+ +L + + +I E + L Sbjct: 230 QLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDL 289 Query: 343 LSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEH 402 + E L EK SRK Q + + +N A+Q Sbjct: 290 NQEFETLQEKAQVNSRKAQTLN----NNVNRATQ-------------------------- 319 Query: 403 ELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLH-NETR 461 S KE+ K+ + ++ + +L++ +WQ+ H E Sbjct: 320 --SAKELDVKI---KNVIRNV---------------------HMLNRIRTWQKTHQGENN 353 Query: 462 TLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQME 521 L + + L++Y AKLSDL+ L +A + A +N+ ++Q + + Sbjct: 354 GLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQS 413 Query: 522 VVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLS--HDL 579 L+T+ SL + L ++ K + A ++ A+ EL K+ LS + L Sbjct: 414 DFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSL 473 Query: 580 VQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALN 639 V+EA HA+ LQ+ A +L ++ + LV+ A+DA+ YENI+N + A + A A + Sbjct: 474 VEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAAS 533 Query: 640 TTDRIYDAV--SGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALAR 697 ++ V + + S+ LLN+A+ Q K + A+ + + + + Sbjct: 534 ASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQ 593 Query: 698 KSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQ 757 K + T L+ L +RGD + ++ + +AN T EV P+ ++ Sbjct: 594 KEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKD 653 Query: 758 NLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQK-RPASNVSASIQRIRELIA 816 + + A+ A ++V LT +P L ++ ++ Q+ P N+S ++ RIRELI Sbjct: 654 TYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQ 713 Query: 817 QTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFIL 876 Q R ASK+ V M F+G+S VEV ++DLK +TSLSL+++ P R E T + F++ Sbjct: 714 QARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSR-ENGGTENMFVM 772 Query: 877 YLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSS--WPAYFSIVKIERVGK 934 YLG+K+A ++Y+G+A+ + L VYNLG ++ E+ +D S A VK +R+ + Sbjct: 773 YLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQ 832 Query: 935 HGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPG 994 ++ T + SS E + + ++LL+LDPE+ VFYVGG P +FKLP+ L+ P Sbjct: 833 FARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPP 892 Query: 995 FVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVR 1054 + GC+EL LN +V+SLYNFK +N++ + PC R K + +F+G+GYA V Sbjct: 893 YKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRK-----EESDKNYFEGTGYARV- 946 Query: 1055 DITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVH 1114 + F ++T D GL+ NG F L + +G L V Y Sbjct: 947 ---PTQPHAPIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVRY---------K 994 Query: 1115 LEDTLKKAQ-----INDAKYHEISI-IYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYI 1168 L L K + IN+ + H I I I K+M + VD ++ +D E F+ Y+ Sbjct: 995 LNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNT-IIDGE--VFDFSTYYL 1051 Query: 1169 GGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISR 1228 GG P I + + FRGCMK KK ++ +T+GV C ED + R Sbjct: 1052 GGIPIAIRERFNISTPA-----FRGCMKNL---KKTSGVVRLNDTVGVTKKCSEDWKLVR 1103 Query: 1229 RAYFN-GQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMD 1287 A F+ G + + D + F F+T QP+G+L + + + ++L++G + + Sbjct: 1104 SASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTLEDGYIELS 1163 Query: 1288 V--KGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKK 1345 G + + Y DGL H+V + L++D + + +++ +S + Sbjct: 1164 TSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSK----RLKHISSSRQS 1219 Query: 1346 FYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLL 1405 GGS NF GCISN + R+ EV D + K SL C + P +L Sbjct: 1220 LRLGGS-------NFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLML 1272 Query: 1406 HKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQY 1465 K +K K + + +D P P ++K+ + C +A A Q+ Sbjct: 1273 LKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKVWQ------DACSPLPKTQANHGALQF 1324 Query: 1466 GGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYM 1525 G S F+ + +SQF++ ++T SS G++F+ +N FM L+L+ GRLV+ Sbjct: 1325 GDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTG--TKNSFMALYLSKGRLVFA 1382 Query: 1526 FNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPI 1585 KKL+I+S+EK NDG WH V+F + GRLV+DGLR E SL P +T I+ P+ Sbjct: 1383 LGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSL-PGNSTISIRAPV 1441 Query: 1586 YLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFS 1645 YLG GK K++ N SF GCL N QL+ + + S +F V+ C GP+E G YFS Sbjct: 1442 YLGSPPSGKP-KSLPTN---SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFS 1497 Query: 1646 TEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNG 1705 EGG+VVL S +G +F++ F +RPRS +G L+H S G++L V+++ G+V +++G Sbjct: 1498 EEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSG 1557 Query: 1706 IRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVG 1765 STSVTPKQSLCDG+WH + V +++ L++D++ ++ G + P +EP+ +G Sbjct: 1558 AGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLG 1617 Query: 1766 GVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSCP 1814 G P +L T R+ K F GC+R+ ++ PV ++A V G VS+N CP Sbjct: 1618 GAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCP 1666 >gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] Length = 1724 Score = 755 bits (1949), Expect = 0.0 Identities = 538/1801 (29%), Positives = 870/1801 (48%), Gaps = 125/1801 (6%) Query: 60 LPPAAEK--CNAGF---FHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCL 114 +PPA + C+ G+ F G+C+ L G + C Sbjct: 1 MPPAVRRSACSMGWLWIFGAALGQCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCS 60 Query: 115 DGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGY 173 GY D C PC C + C ++G+ C+ C N AG +CERC GY Sbjct: 61 PGYYRDHKGLYTGRCVPCNCN-----GHSNQC--QDGSGICVNCQHNTAGEHCERCQEGY 113 Query: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCR-NCLRNTTGFKCERCAPGYYGDA 232 YGN + +C+ C C N C G R +C TG +CERCAPGY+G+ Sbjct: 114 YGNA--VHGSCRACPCPHT---NSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 168 Query: 233 -RIAKNCAVCNCGG----GPCDSVTGECLEEG------FEPPTGCDKCVWDLTDALRLAA 281 + +C C+C G C +TG+C+ + E CD CV L + L Sbjct: 169 QKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMG 228 Query: 282 LSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKS 341 + KS + +S+ A + + L+ +L + + +I E + Sbjct: 229 EQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTD 288 Query: 342 LLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYY--- 398 L + E L EK SRK Q + N+ ++ + A ++ KI+ + + Sbjct: 289 LNQEFETLQEKAQVNSRKAQTLN-------NNVNRATQSAKELDVKIKNVIRNVHILLKQ 341 Query: 399 -----GEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEAD--EAYELLSQAE 451 GE + + + S + AQ+M+ E+R+R + L + EAD E+ LL++ Sbjct: 342 ISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRN---FGKHLREAEADKRESQLLLNRIR 398 Query: 452 SWQRLHN-ETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHE 510 +WQ+ H E L + + L++Y AKLSDL+ L +A + A +N+ + Sbjct: 399 TWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQ 458 Query: 511 KQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLS 570 +Q + + L+T+ SL + L ++ K + A ++ A+ EL K+ Sbjct: 459 RQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVR 518 Query: 571 NLSNLSH--DLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVS 628 LS + LV+EA HA+ LQ+ A +L ++ + LV+ A+DA+ YENI+N + Sbjct: 519 ELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIK 578 Query: 629 EANETAEFALNTTDRIYDAV--SGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVAD 686 A + A A + ++ V + + S+ LLN+A+ Q K + A+ + Sbjct: 579 AAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNN 638 Query: 687 TSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATA 746 + + +K + T L+ L +RGD + ++ + +AN T EV Sbjct: 639 LQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLN 698 Query: 747 PMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKR-PASNVS 805 P+ ++ + + A+ A ++V LT +P L ++ ++ Q+ P N+S Sbjct: 699 PIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNIS 758 Query: 806 ASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRP 865 ++ RIRELI Q R ASK+ V M F+G+S VEV ++DLK +TSLSL+++ P R Sbjct: 759 DNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSR- 817 Query: 866 ELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWP--AY 923 E T + F++YLG+K+A ++Y+G+A+ + L VYNLG ++ E+ +D S A Sbjct: 818 ENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAV 877 Query: 924 FSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSN 983 VK +R+ + ++ T + SS E + + ++LL+LDPE+ VFYVGG P + Sbjct: 878 MDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPD 937 Query: 984 FKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASY 1043 FKLP+ L+ P + GC+EL LN +V+SLYNFK +N++ + PC R K + Sbjct: 938 FKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRK-----EESDKN 992 Query: 1044 FFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVF 1103 +F+G+GYA V + F ++T D GL+ NG F L + +G L V Sbjct: 993 YFEGTGYARVPTQPH----APIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVR 1048 Query: 1104 YDFGFSGGPVHLEDTLKKAQ-----INDAKYHEISI-IYHNDKKMILVVDRRHVKSMDNE 1157 Y L L K + IN+ + H I I I K+M + VD ++ +D E Sbjct: 1049 YK---------LNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNT-IIDGE 1098 Query: 1158 KMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVG 1217 F+ Y+GG P I + + FRGCMK KK ++ +T+GV Sbjct: 1099 VFD--FSTYYLGGIPIAIRERFNISTPA-----FRGCMKNL---KKTSGVVRLNDTVGVT 1148 Query: 1218 YGCPEDSLISRRAYFN--GQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDVF 1275 C ED + R A F+ GQ + + D + F F+T QP+G+L + + + Sbjct: 1149 KKCSEDWKLVRSASFSRGGQLSFTDLG-LPPTDHLQASFGFQTFQPSGILLDHQTWTRNL 1207 Query: 1276 SISLDNGTVIMDVK--GIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTK 1333 ++L++G + + G + + Y DGL H+V + L++D + + Sbjct: 1208 QVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSK--- 1264 Query: 1334 GKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLY 1393 +++ +S + GGS NF GCISN + R+ EV D + K SL Sbjct: 1265 -RLKHISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLG 1316 Query: 1394 ECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHLS 1453 C + P +L K +K K + + +D P P ++K+ + C Sbjct: 1317 GCSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKVWQ------DACSPL 1368 Query: 1454 NSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFM 1513 +A A Q+G S F+ + +SQF++ ++T SS G++F+ + N FM Sbjct: 1369 PKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTK--NSFM 1426 Query: 1514 TLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLP 1573 L+L+ GRLV+ KKL+I+S+EK NDG WH V+F + GRLV+DGLR E SLP Sbjct: 1427 ALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLP 1486 Query: 1574 PTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPC 1633 +T I+ P+YLG GK K++ NS F GCL N QL+ + + S +F V+ C Sbjct: 1487 GN-STISIRAPVYLGSPPSGKP-KSLPTNS---FVGCLKNFQLDSKPLYTPSSSFGVSSC 1541 Query: 1634 FEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHM 1693 GP+E G YFS EGG+VVL S +G +F++ F +RPRS +G L+H S G++L V++ Sbjct: 1542 LGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYL 1601 Query: 1694 KNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNP 1753 + G+V +++G STSVTPKQSLCDG+WH + V +++ L++D++ ++ G + Sbjct: 1602 EAGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPF 1661 Query: 1754 KPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSC 1813 P +EP+ +GG P +L T R+ K F GC+R+ ++ PV ++A V G VS+N C Sbjct: 1662 PPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGC 1721 Query: 1814 P 1814 P Sbjct: 1722 P 1722 >gi|21264602 laminin alpha 5 [Homo sapiens] Length = 3695 Score = 687 bits (1772), Expect = 0.0 Identities = 532/1925 (27%), Positives = 879/1925 (45%), Gaps = 241/1925 (12%) Query: 63 AAEKCNAGFFHTLSG----ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYI 118 + ++C GF+ + G CVPC C+G+S+ CL GSG CV CQ NT G HCE+C G++ Sbjct: 1841 SCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFV 1900 Query: 119 GDSIRGAPQF-CQPCPCPLPHLAN-FAESCYRKNGAVR---------------------- 154 S R P C CPCPL +N FAE C + G + Sbjct: 1901 --SSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGN 1958 Query: 155 ----------CICNEN-----------------------YAGPNCERCAPGYYGNPLLIG 181 C C+ N GP CE CAPG+YGN LL G Sbjct: 1959 PLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPG 2018 Query: 182 STCKKCDC-----------SGNS--------------------------------DPNLI 198 + C +CDC SG+ P Sbjct: 2019 N-CTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAE 2077 Query: 199 FEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGEC--- 255 +C +GQC +C T G +C CAPGY+G + C C C GG CD TG C Sbjct: 2078 GSECHPQSGQC-HCRPGTMGPQCRECAPGYWGLPE--QGCRRCQCPGGRCDPHTGRCNCP 2134 Query: 256 ------------LEEGFEPPTG----------CDKCVWDLTDALRLAALSIEEGKSGVLS 293 + P G CD CV L D L A + + Sbjct: 2135 PGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHCVVLLLDDLERAGALLPAIHEQLRG 2194 Query: 294 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEEL---- 349 +++ + A ++ +NA+I L+++L Q+ E SL D L Sbjct: 2195 INASSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQDARRLGGQA 2254 Query: 350 VEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSP--K 407 V +QAS+ L E+ T+ HA L+ + + E+ ++ + G + +P + Sbjct: 2255 VGTRDQASQL--LAGTEA--TLGHAKTLLAAIRAVDRTLSELMSQTGHLGLANASAPSGE 2310 Query: 408 EISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQA-ESWQRLHNETRTLFPV 466 ++ L +++L E+R+R + + E A LL++ E L E + L Sbjct: 2311 QLLRTLAEVERLLWEMRARD-LGAPQAAAEAELAAAQRLLARVQEQLSSLWEENQALATQ 2369 Query: 467 VLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMS 526 ++L + A L DL+EAL++A++ R+A+++N R + ++++ + + + Sbjct: 2370 TRDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEALQRKQELSRDNATLQAT 2429 Query: 527 LSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDL--VQEAI 584 L + D+L + L LD + + A +DGA++ L ++ S L V+ A Sbjct: 2430 LHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFSPAGSKLRLVEAAE 2489 Query: 585 DHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRI 644 HAQ L Q A LS + + + L Q+A++ASN Y I+ V A + A AL D Sbjct: 2490 AHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQALQQADHT 2549 Query: 645 YDAVSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTR 704 + V + L+++A++L A + ++ +EA+ +R+G A +T+ Sbjct: 2550 WATVV------------RQGLVDRAQQLLANS-TALEEAMLQEQQRLGLVWAALQGARTQ 2596 Query: 705 LSD-------------AVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANN 751 L D A + + A + + +++ ++ + EA T VQ M N Sbjct: 2597 LRDVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAAEAQDTATRVQSQLQAMQEN 2656 Query: 752 LTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQK---RPASNVSASI 808 + W + AV A +V L + +PQLL +L +E + + +SASI Sbjct: 2657 VERWQGQYEGLRGQDLGQAVLDAGHSVSTLEKTLPQLLAKLSILENRGVHNASLALSASI 2716 Query: 809 QRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELT 868 R+RELIAQ R ASK++V M F+G+S V++ + + DL A+T+L Y++ P P Sbjct: 2717 GRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYTALKFYLQGPEPEPG-Q 2775 Query: 869 ETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVK 928 T D+F++Y+GS+ A +YMG+++++ + +VY LG + + + F+ V Sbjct: 2776 GTEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQLGEAGPAVLSIDEDIGE---QFAAVS 2832 Query: 929 IERVGKHGKVFLTVPSLSSTAEEKFIK--KGEF--SGDDSLLDLDPEDTVFYVGGVPSNF 984 ++R + G + +TV E + I+ KG+ G + LL+L P+D VFYVGG PS F Sbjct: 2833 LDRTLQFGHMSVTV-------ERQMIQETKGDTVAPGAEGLLNLRPDDFVFYVGGYPSTF 2885 Query: 985 KLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYF 1044 P L PG+ GC+E+ TLN +V+SLYNF+ + +D + PCAR K + Sbjct: 2886 TPPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDPWLTDGSY 2945 Query: 1045 FDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFY 1104 DG+G+A I+ + RF+ E+R + +G++ + S F L ++ G L + Y Sbjct: 2946 LDGTGFA---RISFDSQISTTKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQEGSLVLLY 3002 Query: 1105 DFGF---SGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKI 1161 DFG P+ L A +K ++ ++ + K++++ V+R V S++ + Sbjct: 3003 DFGAGLKKAVPLQPPPPLTSA----SKAIQVFLLGGSRKRVLVRVERATVYSVEQDNDLE 3058 Query: 1162 PFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYGCP 1221 Y+GG PP+ L +LR P + RGC+KG + K + L++ T GV GC Sbjct: 3059 LADAYYLGGVPPDQLPP-SLRRLFPTGGSVRGCVKGIKALGKYVD-LKRLNTTGVSAGCT 3116 Query: 1222 EDSLISRRAYFNGQSFI-ASIQKISFFDG-FEGGFNFRTLQPNGLLFYYASGSDVFSISL 1279 D L+ R F+G F+ ++ ++ G GF F + Q + LL+Y AS + +SL Sbjct: 3117 ADLLVGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYYRASPDGLCQVSL 3176 Query: 1280 DNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQT 1339 G V + + +V++ + DG H+V + T L VD ++ P +G + Sbjct: 3177 QQGRVSLQLLRTEVKT-QAGFADGAPHYVAFYSNATGVWLYVD-DQLQQMKPHRGPPPEL 3234 Query: 1340 QASEK---KFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECP 1396 Q + + GG P S NF+GCISN + R+ V D Q+ V+ S P Sbjct: 3235 QPQPEGPPRLLLGGLPESGTIYNFSGCISNVFVQRLLGPQRVFDLQQNLGSVNVSTGCAP 3294 Query: 1397 IESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSP 1456 + L +G + KAS+ + P+ P + P T R+S Sbjct: 3295 ALQAQTPGLGPRGLQATARKASRRSR------QPARHPACMLPPHLRTTRDS-------- 3340 Query: 1457 RAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSD-QEENDFMTL 1515 YQ+GG+ +S EF + S+ + RSS G++ + + + + + L Sbjct: 3341 ------YQFGGSLSSHLEFVGILARHRNWPSLSMHVLPRSSRGLLLFTARLRPGSPSLAL 3394 Query: 1516 FLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPT 1575 FL++G V +L+ +S+++ G WH V E++ LV DG R + P Sbjct: 3395 FLSNGHFVAQMEGLGTRLRAQSRQRSRPGRWHKVSVRWEKNRILLVTDGARAWSQEGPHR 3454 Query: 1576 E---ATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTP 1632 + A +++GG+ + + FSGC+ L+L+G + + ++ VTP Sbjct: 3455 QHQGAEHPQPHTLFVGGLPASSHSSKLPVT--VGFSGCVKRLRLHGRPLGAPTRMAGVTP 3512 Query: 1633 CFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH-GHSVNGEYLNV 1691 C GP+E G +F GG + LD + EVRP + +G + H G + YL + Sbjct: 3513 CILGPLEAGLFFPGSGGVITLDLPGATLPDVGLELEVRPLAVTGLIFHLGQARTPPYLQL 3572 Query: 1692 HMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPL 1751 + QV+++ ++G +FSTSVT LCDG+WHR+ V++ NV++L+VD++ NH VGPL Sbjct: 3573 QVTEKQVLLRADDGAGEFSTSVTRPSVLCDGQWHRLAVMKSGNVLRLEVDAQSNHTVGPL 3632 Query: 1752 NPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSIN 1811 P+++GG+PE + P+ + GC+R ++ PV+ +++ V GAV + Sbjct: 3633 LAAAAGAPAPLYLGGLPEPMAVQPWPPA--YCGCMRRLAVNRSPVAMTRSVEVHGAVGAS 3690 Query: 1812 SCPAA 1816 CPAA Sbjct: 3691 GCPAA 3695 Score = 103 bits (256), Expect = 2e-21 Identities = 71/231 (30%), Positives = 98/231 (42%), Gaps = 46/231 (19%) Query: 76 SGECVPCDCNGNSNEC--------------LDGS----GYCVHCQRNTTGEHCEKCLDGY 117 + EC C+C G++ +C LDG+ G C+ CQ +TTG +CE+CL G+ Sbjct: 353 ANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGF 412 Query: 118 IGDSIR--GAPQFCQPCPCPLPHLANFAE-SCYRKNGAVRCICNENYAGPNCERCAPGYY 174 +P C+ C C ++F + +C G RC C N++G C+ CA G+ Sbjct: 413 YRSPNHPLDSPHVCRRCNCE----SDFTDGTCEDLTG--RCYCRPNFSGERCDVCAEGFT 466 Query: 175 GNP---------------LLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGF 219 G P +L CDCS D G+C C N G Sbjct: 467 GFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRK-DPRVGRCL-CKPNFQGT 524 Query: 220 KCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGEC-LEEGFEPPTGCDKC 269 CE CAPG+YG C+ CD TG+C GFE T CD+C Sbjct: 525 HCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGAT-CDRC 574 Score = 102 bits (254), Expect = 3e-21 Identities = 73/244 (29%), Positives = 98/244 (40%), Gaps = 42/244 (17%) Query: 40 SAVGRQDPPETSEPRVALGRLPPA-----AEKCNAGFFHTLSGECVPCDCNGNS---NEC 91 SA G Q +PRV P E C GF+ C PC C+ + C Sbjct: 497 SAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFY---GPGCQPCQCSSPGVADDRC 553 Query: 92 LDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNG 151 +G C C+ G C++C GY + CQ C C E C + Sbjct: 554 DPDTGQC-RCRVGFEGATCDRCAPGYFHFPL------CQLCGCS--PAGTLPEGC---DE 601 Query: 152 AVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRN 211 A RC+C +AGP+C+RC PGY+G P C+ C C DP + G CR Sbjct: 602 AGRCLCQPEFAGPHCDRCRPGYHGFP-----NCQACTC----DPRGALDQLCGAGGLCR- 651 Query: 212 CLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGC 266 C TG C+ C+PG++G +C C+C CD +G+C C Sbjct: 652 CRPGYTGTACQECSPGFHG----FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRC 707 Query: 267 DKCV 270 D CV Sbjct: 708 DTCV 711 Score = 100 bits (250), Expect = 1e-20 Identities = 66/198 (33%), Positives = 90/198 (45%), Gaps = 33/198 (16%) Query: 81 PCDCN---GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137 PC C+ C G C C + G C +C GY G P C+PC C Sbjct: 1437 PCGCHEVGATGPTCEPFGGQCP-CHAHVIGRDCSRCATGYWG-----FPN-CRPCDCG-- 1487 Query: 138 HLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNL 197 A C G +CIC P+C C P +G L+G C++C+CSG L Sbjct: 1488 -----ARLCDELTG--QCICPPRTIPPDCLLCQPQTFGCHPLVG--CEECNCSGPGIQEL 1538 Query: 198 IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC-----GGGPCDSVT 252 CD +GQC+ C N TG +C+ C+PG++G R C C+C G CD +T Sbjct: 1539 TDPTCDTDSGQCK-CRPNVTGRRCDTCSPGFHGYPR----CRPCDCHEAGTAPGVCDPLT 1593 Query: 253 GEC-LEEGFEPPTGCDKC 269 G+C +E + P CD+C Sbjct: 1594 GQCYCKENVQGPK-CDQC 1610 Score = 84.3 bits (207), Expect = 1e-15 Identities = 61/211 (28%), Positives = 85/211 (40%), Gaps = 24/211 (11%) Query: 63 AAEKCNAGFFHTLSGECVPCDCNGNSN---ECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119 A ++C+ GF S CVPC C+ + C SG C C+ TG C+ C+ G Sbjct: 660 ACQECSPGFHGFPS--CVPCHCSAEGSLHAACDPRSGQC-SCRPRVTGLRCDTCVPGAYN 716 Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179 +C+ C LA + V C+C + GP+C+RC PG++G Sbjct: 717 FP------YCEAGSCHPAGLAPVDPAL--PEAQVPCMCRAHVEGPSCDRCKPGFWGLSPS 768 Query: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNC 238 C +C C + E C TGQC C + G C C G++G D C Sbjct: 769 NPEGCTRCSCDLRGTLGGVAE-CQPGTGQC-FCKPHVCGQACASCKDGFFGLDQADYFGC 826 Query: 239 AVCNCGGGPCDSVTGECLEEGFEPPTGCDKC 269 C C G L + EP TG +C Sbjct: 827 RSCRCD-------IGGALGQSCEPRTGVCRC 850 Score = 83.2 bits (204), Expect = 2e-15 Identities = 55/171 (32%), Positives = 77/171 (45%), Gaps = 23/171 (13%) Query: 79 CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG-DSIRGAPQFCQPCPCPLP 137 C PCDC C + +G C+ C T C C G + G C+ C C P Sbjct: 1481 CRPCDCGARL--CDELTGQCI-CPPRTIPPDCLLCQPQTFGCHPLVG----CEECNCSGP 1533 Query: 138 HLANFAE-SCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDC-SGNSDP 195 + + +C +G +C C N G C+ C+PG++G P C+ CDC + P Sbjct: 1534 GIQELTDPTCDTDSG--QCKCRPNVTGRRCDTCSPGFHGYP-----RCRPCDCHEAGTAP 1586 Query: 196 NLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCGG 245 + CD +TGQC C N G KC++C+ G + DA K C C C G Sbjct: 1587 GV----CDPLTGQCY-CKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFG 1632 Score = 77.0 bits (188), Expect = 2e-13 Identities = 65/250 (26%), Positives = 97/250 (38%), Gaps = 69/250 (27%) Query: 74 TLSGECVPCDCNGNSNEC-----LDGSGYCVHCQRNTTGEHCEKCLDGYIGD----SIRG 124 ++ G CV C+G+++ C D CQ NT G C++C G+ + Sbjct: 295 SIGGRCV---CHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATAN 351 Query: 125 APQFCQPCPCPLPHLANFAESCY-----------------RKNGAVRCICNENYAGPNCE 167 + CQ C C A CY + G V C + G NCE Sbjct: 352 SANECQSCNC-----YGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCE 406 Query: 168 RCAPGYY---GNPLLIGSTCKKCDCSGNSDPNLIFED--CDEVTGQCRNCLRNTTGFKCE 222 RC PG+Y +PL C++C+C + F D C+++TG+C C N +G +C+ Sbjct: 407 RCLPGFYRSPNHPLDSPHVCRRCNCESD------FTDGTCEDLTGRC-YCRPNFSGERCD 459 Query: 223 RCAPGYYG------------DAR---------IAKNCAVCNCGGGPC--DSVTGECLEEG 259 CA G+ G D R + +C+ G C D G CL + Sbjct: 460 VCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKP 519 Query: 260 FEPPTGCDKC 269 T C+ C Sbjct: 520 NFQGTHCELC 529 Score = 70.5 bits (171), Expect = 1e-11 Identities = 45/161 (27%), Positives = 66/161 (40%), Gaps = 29/161 (18%) Query: 143 AESCYRKNGA----VRCICNENYAGPNCERCAPGYYGNP-----LLIGSTCKKCDCSGNS 193 A++C K+ ++C C N G C+RC PG+ P + C+ C+C G++ Sbjct: 306 ADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHA 365 Query: 194 -----DPNL-------IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN---- 237 DP + + + G C +C +TTG CERC PG+Y + Sbjct: 366 TDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHV 425 Query: 238 CAVCNCGG----GPCDSVTGECLEEGFEPPTGCDKCVWDLT 274 C CNC G C+ +TG C CD C T Sbjct: 426 CRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFT 466 Score = 65.9 bits (159), Expect = 4e-10 Identities = 46/144 (31%), Positives = 63/144 (43%), Gaps = 22/144 (15%) Query: 60 LPPAAEKCNAGFF--HTLSGECVPCDCNGNSNE------CLDGSGYCVHCQRNTTGEHCE 111 +PP C F H L G C C+C+G + C SG C C+ N TG C+ Sbjct: 1505 IPPDCLLCQPQTFGCHPLVG-CEECNCSGPGIQELTDPTCDTDSGQC-KCRPNVTGRRCD 1562 Query: 112 KCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAES-CYRKNGAVRCICNENYAGPNCERCA 170 C G+ G P+ C+PC C H A A C G +C C EN GP C++C+ Sbjct: 1563 TCSPGF-----HGYPR-CRPCDC---HEAGTAPGVCDPLTG--QCYCKENVQGPKCDQCS 1611 Query: 171 PGYYGNPLLIGSTCKKCDCSGNSD 194 G + C +C C G ++ Sbjct: 1612 LGTFSLDAANPKGCTRCFCFGATE 1635 Score = 62.8 bits (151), Expect = 3e-09 Identities = 33/92 (35%), Positives = 45/92 (48%), Gaps = 10/92 (10%) Query: 155 CICNENYAGPNCERCAPGYYGN--PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNC 212 C+C +Y G +C+ CAPG+Y + L +G C C C G+SD C +G C +C Sbjct: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLG-RCVPCQCHGHSD------RCLPGSGVCVDC 1883 Query: 213 LRNTTGFKCERCAPGYYGDA-RIAKNCAVCNC 243 NT G CERC G+ + C C C Sbjct: 1884 QHNTEGAHCERCQAGFVSSRDDPSAPCVSCPC 1915 Score = 59.3 bits (142), Expect = 3e-08 Identities = 48/169 (28%), Positives = 69/169 (40%), Gaps = 23/169 (13%) Query: 21 CSRAASGDDNAFPFDIEGS---SAVGRQDP--PETSEPRVALGRLP-PAAEKCNAGFFHT 74 C G N FP+ GS + + DP PE P + + P+ ++C GF+ Sbjct: 707 CDTCVPGAYN-FPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGL 765 Query: 75 LSGE---CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126 C C C+ G EC G+G C C+ + G+ C C DG+ G + A Sbjct: 766 SPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCF-CKPHVCGQACASCKDGFFG--LDQAD 822 Query: 127 QF-CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174 F C+ C C + +SC + G C C N GP C A +Y Sbjct: 823 YFGCRSCRCDIG--GALGQSCEPRTGV--CRCRPNTQGPTCSEPARDHY 867 Score = 53.5 bits (127), Expect = 2e-06 Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 34/122 (27%) Query: 178 LLIGSTCKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235 L + + C C G + P C+ GQC C + G C RCA GY+G Sbjct: 1429 LFYNNGARPCGCHEVGATGPT-----CEPFGGQCP-CHAHVIGRDCSRCATGYWG----F 1478 Query: 236 KNCAVCNCGGGPCDSVTGECL----------------EEGFEPPTGCDKC------VWDL 273 NC C+CG CD +TG+C+ G P GC++C + +L Sbjct: 1479 PNCRPCDCGARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQEL 1538 Query: 274 TD 275 TD Sbjct: 1539 TD 1540 >gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sapiens] Length = 3122 Score = 421 bits (1082), Expect = e-117 Identities = 450/1858 (24%), Positives = 778/1858 (41%), Gaps = 219/1858 (11%) Query: 57 LGRLPPAAEKCNAGFFHTLS-----------GECVPCDCNGNSNECLDGSGYCVHCQRNT 105 LG + E C GF+ S G CVPC CNG+S+ C + C +CQ +T Sbjct: 1384 LGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHT 1443 Query: 106 TGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLA-NFAESCYRKN-GAVRC-ICNENYA 162 G+ CE+C GY G ++G P CQ C CPL + NF+ SC + RC C Y Sbjct: 1444 AGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYE 1502 Query: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDP-NLIFEDCDEVTGQCRNCLRNTTGFKC 221 G CERCAPGY G+P G +C++C+C DP + CD VTG C C TG KC Sbjct: 1503 GQYCERCAPGYTGSPGNPGGSCQECEC----DPYGSLPVPCDPVTGFC-TCRPGATGRKC 1557 Query: 222 ERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAA 281 + C + AR C C G C + L D RL Sbjct: 1558 DGCK---HWHAREGWECVFC---GDECTGLL--------------------LGDLARLEQ 1591 Query: 282 LSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKS 341 + + +G L A ++ + + LK LS + L I AE + + Sbjct: 1592 MVMSINLTGPL-----PAPYKMLYGLENMTQELKHLLSPQRAPERL----IQLAEGNLNT 1642 Query: 342 LLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEE 401 L++++ EL+ + + + G+ +++ T A L E ++ + +N K + E Sbjct: 1643 LVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNET 1702 Query: 402 HELSPKEISEKLVLAQK----MLEEIRSRQPFFTQRELVDEEADEAYELLSQAES-WQRL 456 + L QK M++E+R R+ TQ+E+ ++E A LL + + + Sbjct: 1703 LGTRDEAFERNLEGLQKEIDQMIKELR-RKNLETQKEIAEDELVAAEALLKKVKKLFGES 1761 Query: 457 HNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDH---EKQQ 513 E + + E+L DY K+ D + L +A + +R+A NR A Q++ EK++ Sbjct: 1762 RGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREA---NRLFAVNQKNMTALEKKK 1818 Query: 514 ERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLS 573 E V + +L D L E++ II I ++ EL K+ +LS Sbjct: 1819 EAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLS 1878 Query: 574 NLSHD-LVQEAIDHAQDLQQEANELSRKLHS--SDMNGLVQKALDASNVYENIVNYVSEA 630 D + E + A+ + N+ S L + + A A Y NI +Y+ EA Sbjct: 1879 QEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFKAYSNIKDYIDEA 1938 Query: 631 NETAEFALNTTDRIYDAVSG----IDTQIIYHKDESENLLNQARELQAKAESSSDEAVAD 686 + A+ A + +G + +S +LN+A++L + + D + Sbjct: 1939 EKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVKENEDH-LNG 1997 Query: 687 TSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATA 746 R+ A AR L L+D + +L A D +L + +AN T +V Sbjct: 1998 LKTRIENADARNGDLLRTLNDTLGKLSAIP-NDTAAKLQAVKDKARQANDTAKDVLAQIT 2056 Query: 747 PMANNLTNWSQNLQHFDSS-----------AYNTAVNSARDAVRNLTEVVPQLLDQLRTV 795 + NL +N S + N + A V+NL + +L+D+L+ + Sbjct: 2057 ELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPI 2116 Query: 796 EQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLK--AFTS 853 K N+ +I I+ELI Q R A+ I+VS+ G RT ++K ++ + Sbjct: 2117 --KELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCI-----RTYKPEIKKGSYNN 2169 Query: 854 LSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLD 913 + + +K T AD + YLGS +++ + ++ + +++++G+ + Sbjct: 2170 IVVNVK--------TAVADNLLFYLGSAKF-IDFLAIEMRKGKVSFLWDVGSGVGRVEYP 2220 Query: 914 SKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDT 973 + +Y+ + R G++G + + + ++LD+D + Sbjct: 2221 DLTIDD--SYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVD-ANA 2277 Query: 974 VFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIY-NMDPSTSVPCARDK 1032 + +VGG+ K ++ + F GC+ +N I L+NF+ + T P D Sbjct: 2278 MLFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDS 2337 Query: 1033 LAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSM--F 1090 Q FDG GYA+V R + ++ + RT + + L++ + + F Sbjct: 2338 EGTIQ-------FDGEGYALVSRPIR--WYPNISTVMFKFRTFSSSALLMYLATRDLRDF 2388 Query: 1091 FRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVD--- 1147 +E+ +G++ V YD G SG + + ND K+ ++ + I +VD Sbjct: 2389 MSVELTDGHIKVSYDLG-SG----MASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDT 2443 Query: 1148 --RRHV---KSMDNEKMKIPFTD-IYIGGAPPEILQSRALRAHLPLDI-NFRGCMKGFQF 1200 ++ S +N + + D IY GG P L++ +++A +++ + GC+K + Sbjct: 2444 NQEENIATSSSGNNFGLDLKADDKIYFGGLP--TLRNLSMKARPEVNLKKYSGCLKDIEI 2501 Query: 1201 QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ 1260 + +N+L + +GV GC +++ + F F+ + + G E +F T Sbjct: 2502 SRTPYNILSSPDYVGVTKGCSLENVYT--VSFPKPGFV-ELSPVPIDVGTEINLSFSTKN 2558 Query: 1261 PNGLLFYYASGSDV-------------FSISLDNG-------TVIMDVKGIKVQSVDKQY 1300 +G++ + G+ + I L+ G T ++ I ++ + Sbjct: 2559 ESGIILLGSGGTPAPPRRKRRQTGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLF 2618 Query: 1301 NDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQ---- 1356 +DG H V + + + VD++R +N T +EQ KK + GG+P Q Sbjct: 2619 HDGREHSVHVERTRGIFTVQVDENRRYMQNLT---VEQ-PIEVKKLFVGGAPPEFQPSPL 2674 Query: 1357 --YANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSK 1414 F GCI N V DF R + + C + Sbjct: 2675 RNIPPFEGCIWNLVINSVPM-----DFARPVSFKNADIGRC-----------------AH 2712 Query: 1415 PKASQNKKGGKSKD-APSWDPVALKLPERNTPRNSH--CHLSNSPRAIEHAYQYGGTANS 1471 K +++ G + +PV TP +H C + P + + Q+G + NS Sbjct: 2713 QKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALLIGSKQFGLSRNS 2772 Query: 1472 RQEFEHLKGDFGAKSQFSIRL--RTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVG 1529 D K++ +I L RT + G++FY++ DF T+ L +G + +++G Sbjct: 2773 HIAIAF--DDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLG 2830 Query: 1530 HKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEA-TWKIKGPIYLG 1588 K NDG WH + +R + G L +DG ++ P +A + G +Y+G Sbjct: 2831 SGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDG--ASNRTISPKKADILDVVGMLYVG 2888 Query: 1589 GVAPGKAVKNVQINSIYSFSGCLSNLQL--NGASITSASQTFSVTPCFEGPMETGTYFST 1646 G+ + + YS GC+ NL + A + + +F V CF + GTYF Sbjct: 2889 GLPINYTTRRIG-PVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFAN-AQRGTYFDG 2946 Query: 1647 EGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGI 1706 G+ F +GL + FE R +++G L+ S + + + M + +++ V+NG Sbjct: 2947 T-GFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFHVDNGA 3005 Query: 1707 RDFST--SVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNP--KPIDHREPV 1762 F+ LCDG+WH++T + + ++L VD P NP D +PV Sbjct: 3006 GRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSP-NPASTSADTNDPV 3064 Query: 1763 FVGGVPESLLTPRLAPSKPFTGCIRHFVI---DGHP--VSFSKAALVSGAVSINSCPA 1815 FVGG P+ L L S PF GCIR + G P V+F+KA + G + SCPA Sbjct: 3065 FVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPV-SCPA 3121 Score = 175 bits (444), Expect = 3e-43 Identities = 88/216 (40%), Positives = 117/216 (54%), Gaps = 12/216 (5%) Query: 62 PAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121 P + N F G C PC C G++ C D +G C++C+ +T G +C+KCL G+ G+ Sbjct: 740 PRHRRVNGTIF---GGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEP 796 Query: 122 IRGAPQFCQPCPCPLPHLA-NFAESCY--RKNGAVRCICNENYAGPNCERCAPGYYGNPL 178 +G + CQPC CPL + NF+ +C+ R G + C Y GP CERCA GY+G P Sbjct: 797 TKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS 856 Query: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC 238 + G +C+ C C+ N D + I CD ++G C C TTG CE CA GY+GDA AKNC Sbjct: 857 VPGGSCQPCQCNDNLDFS-IPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNC 915 Query: 239 AVCNCGGG-----PCDSVTGECLEEGFEPPTGCDKC 269 C C G C S TG+C CDKC Sbjct: 916 QPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKC 951 Score = 132 bits (332), Expect = 3e-30 Identities = 79/223 (35%), Positives = 106/223 (47%), Gaps = 25/223 (11%) Query: 57 LGRLPPAAEKCNAGFFHTLS---GECVPCDCNGNSNECLDGS-----GYCVHCQRNTTGE 108 +G P E+C G+F S G C PC CN N + + GS G C+ C+ TTG Sbjct: 837 VGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGR 896 Query: 109 HCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCER 168 +CE C DGY GD++ + CQPC C +F+E C+ + G +C C N G C++ Sbjct: 897 YCELCADGYFGDAVDA--KNCQPCRCNAG--GSFSEVCHSQTG--QCECRANVQGQRCDK 950 Query: 169 CAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGY 228 C G +G L C C+C+ + DC+E +GQC C TG KC+RCA GY Sbjct: 951 CKAGTFG--LQSARGCVPCNCNSFGSKSF---DCEE-SGQCW-CQPGVTGKKCDRCAHGY 1003 Query: 229 YGDARIAKNCAVCNCG--GGPCDSVTGECLEEGFEPPTGCDKC 269 + C C C G CD TG C+ C KC Sbjct: 1004 FNFQE--GGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKC 1044 Score = 110 bits (275), Expect = 1e-23 Identities = 74/199 (37%), Positives = 98/199 (49%), Gaps = 30/199 (15%) Query: 65 EKCNAGFFHTLSGE-CVPCDCNGNSNECLD--GSGYCVHCQRNTTGEHCEKCLDGYIGDS 121 +KC AG F S CVPC+CN ++ D SG C CQ TG+ C++C GY Sbjct: 949 DKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQC-WCQPGVTGKKCDRCAHGYFNFQ 1007 Query: 122 IRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIG 181 G C C C HL N +C K G RCIC N G C +CAP +G+ + G Sbjct: 1008 EGG----CTACECS--HLGN---NCDPKTG--RCICPPNTIGEKCSKCAPNTWGHSITTG 1056 Query: 182 STCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVC 241 CK C+CS + +L F+ C+ TGQC NC +G KC C+ G++ R C +C Sbjct: 1057 --CKACNCS--TVGSLDFQ-CNVNTGQC-NCHPKFSGAKCTECSRGHWNYPR----CNLC 1106 Query: 242 NC-----GGGPCDSVTGEC 255 +C CDS T +C Sbjct: 1107 DCFLPGTDATTCDSETKKC 1125 Score = 102 bits (254), Expect = 3e-21 Identities = 63/200 (31%), Positives = 87/200 (43%), Gaps = 26/200 (13%) Query: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124 ++C G+F+ G C C+C+ N C +G C+ C NT GE C KC G SI Sbjct: 997 DRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCI-CPPNTIGEKCSKCAPNTWGHSITT 1055 Query: 125 APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184 C+ C C +F C G +C C+ ++G C C+ G++ P C Sbjct: 1056 G---CKACNCSTVGSLDF--QCNVNTG--QCNCHPKFSGAKCTECSRGHWNYP-----RC 1103 Query: 185 KKCDC------SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKN 237 CDC + D C + TGQC C N G C+RC PG +G DA+ Sbjct: 1104 NLCDCFLPGTDATTCDSETKKCSCSDQTGQC-TCKVNVEGIHCDRCRPGKFGLDAKNPLG 1162 Query: 238 CAVCNCGGGPCDSVTGECLE 257 C+ C C G T +C E Sbjct: 1163 CSSCYCFG-----TTTQCSE 1177 Score = 99.8 bits (247), Expect = 2e-20 Identities = 76/261 (29%), Positives = 105/261 (40%), Gaps = 48/261 (18%) Query: 69 AGFFHTLSGECVPCDCNGNSNECLD------------------GSGYCVHCQRNTTGEHC 110 AG F T + EC C+C+G + EC G G C++C +NT G +C Sbjct: 332 AGTFLTKT-ECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINC 390 Query: 111 EKCLDGYIGDSIRGAPQFCQPC-PCPLPHLANFAESCYRKNGAVR-------CICNENYA 162 E C DG+ +P + +PC PC + + E C + R C C + Sbjct: 391 ETCTDGFFRPK-GVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFG 449 Query: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCE 222 G +C+RCA GY G P CK C+CSG N D G C C N G C Sbjct: 450 GVSCDRCARGYTGYP-----DCKACNCSGLGSKNE-----DPCFGPC-ICKENVEGGDCS 498 Query: 223 RCAPGYYG-DARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTD---ALR 278 RC G++ K C C C G V+ C + D W LTD +R Sbjct: 499 RCKSGFFNLQEDNWKGCDECFCSG-----VSNRCQSSYWTYGKIQDMSGWYLTDLPGRIR 553 Query: 279 LAALSIEEGKSGVLSVSSGAA 299 +A + +S+S+ A Sbjct: 554 VAPQQDDLDSPQQISISNAEA 574 Score = 77.0 bits (188), Expect = 2e-13 Identities = 53/175 (30%), Positives = 72/175 (41%), Gaps = 42/175 (24%) Query: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRK----NGAV----------------------R 154 SI A + CQ CP + + ESC+ + NG + Sbjct: 716 SIAAAVEVCQ---CPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGE 772 Query: 155 CI-CNENYAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDC--DEVTGQ-C 209 C+ C ++ GP C++C PG+YG P C+ C C N N C D G C Sbjct: 773 CLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLIC 832 Query: 210 RNCLRNTTGFKCERCAPGYYGDARI-AKNCAVCNCGG-------GPCDSVTGECL 256 C TG +CERCA GY+G + +C C C G CDS++G CL Sbjct: 833 DGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCL 887 Score = 70.9 bits (172), Expect = 1e-11 Identities = 67/239 (28%), Positives = 91/239 (38%), Gaps = 58/239 (24%) Query: 82 CDCNGNSNEC-LD---GSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137 C C G++ C LD C C+ NT G+ C++C G+ R A F C Sbjct: 287 CICYGHARACPLDPATNKSRC-ECEHNTCGDSCDQCCPGFHQKPWR-AGTFLTKTECEAC 344 Query: 138 HLANFAESCY------RKN-----------GAVRCICNENYAGPNCERCAPGYY---GNP 177 + AE CY R+N G V C +N AG NCE C G++ G Sbjct: 345 NCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVS 404 Query: 178 LLIGSTCKKCDCSGNSDPNLIFEDCDE------VTGQCRNCLRNTTGFKCERCAPGYYGD 231 C+ C C N + ++ G C +C G C+RCA GY G Sbjct: 405 PNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSC-HCKTGFGGVSCDRCARGYTG- 462 Query: 232 ARIAKNCAVCNCGG----------GPC----DSVTGEC--LEEGF-----EPPTGCDKC 269 +C CNC G GPC + G+C + GF + GCD+C Sbjct: 463 ---YPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDEC 518 >gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo sapiens] Length = 3118 Score = 419 bits (1078), Expect = e-116 Identities = 452/1857 (24%), Positives = 773/1857 (41%), Gaps = 221/1857 (11%) Query: 57 LGRLPPAAEKCNAGFFHTLS-----------GECVPCDCNGNSNECLDGSGYCVHCQRNT 105 LG + E C GF+ S G CVPC CNG+S+ C + C +CQ +T Sbjct: 1384 LGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHT 1443 Query: 106 TGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLA-NFAESCYRKN-GAVRC-ICNENYA 162 G+ CE+C GY G ++G P CQ C CPL + NF+ SC + RC C Y Sbjct: 1444 AGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYE 1502 Query: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDP-NLIFEDCDEVTGQCRNCLRNTTGFKC 221 G CERCAPGY G+P G +C++C+C DP + CD VTG C C TG KC Sbjct: 1503 GQYCERCAPGYTGSPGNPGGSCQECEC----DPYGSLPVPCDPVTGFC-TCRPGATGRKC 1557 Query: 222 ERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAA 281 + C + AR C C G C + L D RL Sbjct: 1558 DGCK---HWHAREGWECVFC---GDECTGLL--------------------LGDLARLEQ 1591 Query: 282 LSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKS 341 + + +G L A ++ + + LK LS + L I AE + + Sbjct: 1592 MVMSINLTGPL-----PAPYKMLYGLENMTQELKHLLSPQRAPERL----IQLAEGNLNT 1642 Query: 342 LLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEE 401 L++++ EL+ + + + G+ +++ T A L E ++ + +N K + E Sbjct: 1643 LVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNET 1702 Query: 402 HELSPKEISEKLVLAQK----MLEEIRSRQPFFTQRELVDEEADEAYELLSQAES-WQRL 456 + L QK M++E+R R+ TQ+E+ ++E A LL + + + Sbjct: 1703 LGTRDEAFERNLEGLQKEIDQMIKELR-RKNLETQKEIAEDELVAAEALLKKVKKLFGES 1761 Query: 457 HNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDH---EKQQ 513 E + + E+L DY K+ D + L +A + +R+A NR A Q++ EK++ Sbjct: 1762 RGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREA---NRLFAVNQKNMTALEKKK 1818 Query: 514 ERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLS 573 E V + +L D L E++ II I ++ EL K+ +LS Sbjct: 1819 EAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLS 1878 Query: 574 NLSHD-LVQEAIDHAQDLQQEANELSRKLHS--SDMNGLVQKALDASNVYENIVNYVSEA 630 D + E + A+ + N+ S L + + A A Y NI +Y+ EA Sbjct: 1879 QEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFKAYSNIKDYIDEA 1938 Query: 631 NETAEFALNTTDRIYDAVSG----IDTQIIYHKDESENLLNQARELQAKAESSSDEAVAD 686 + A+ A + +G + +S +LN+A++L + + D + Sbjct: 1939 EKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVKENEDH-LNG 1997 Query: 687 TSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATA 746 R+ A AR L L+D + +L A D +L + +AN T +V Sbjct: 1998 LKTRIENADARNGDLLRTLNDTLGKLSAIP-NDTAAKLQAVKDKARQANDTAKDVLAQIT 2056 Query: 747 PMANNLTNWSQNLQHFDSS-----------AYNTAVNSARDAVRNLTEVVPQLLDQLRTV 795 + NL +N S + N + A V+NL + +L+D+L+ + Sbjct: 2057 ELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPI 2116 Query: 796 EQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLK--AFTS 853 K N+ +I I+ELI Q R A+ I+VS+ G RT ++K ++ + Sbjct: 2117 --KELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCI-----RTYKPEIKKGSYNN 2169 Query: 854 LSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLD 913 + + +K T AD + YLGS +++ + ++ + +++++G+ + Sbjct: 2170 IVVNVK--------TAVADNLLFYLGSAKF-IDFLAIEMRKGKVSFLWDVGSGVGRVEYP 2220 Query: 914 SKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDT 973 + +Y+ + R G++G + + + ++LD+D + Sbjct: 2221 DLTIDD--SYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVD-ANA 2277 Query: 974 VFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIY-NMDPSTSVPCARDK 1032 + +VGG+ K ++ + F GC+ +N I L+NF+ + T P D Sbjct: 2278 MLFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDS 2337 Query: 1033 LAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSM--F 1090 Q FDG GYA+V R + ++ + RT + + L++ + + F Sbjct: 2338 EGTIQ-------FDGEGYALVSRPIR--WYPNISTVMFKFRTFSSSALLMYLATRDLRDF 2388 Query: 1091 FRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVD--- 1147 +E+ +G++ V YD G SG + + ND K+ ++ + I +VD Sbjct: 2389 MSVELTDGHIKVSYDLG-SG----MASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDT 2443 Query: 1148 --RRHV---KSMDNEKMKIPFTD-IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQ 1201 ++ S +N + + D IY GG P R LR + L + GC+K + Sbjct: 2444 NQEENIATSSSGNNFGLDLKADDKIYFGGLP----TLRNLRPEVNLK-KYSGCLKDIEIS 2498 Query: 1202 KKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQP 1261 + +N+L + +GV GC +++ + F F+ + + G E +F T Sbjct: 2499 RTPYNILSSPDYVGVTKGCSLENVYT--VSFPKPGFV-ELSPVPIDVGTEINLSFSTKNE 2555 Query: 1262 NGLLFYYASGSDV-------------FSISLDNG-------TVIMDVKGIKVQSVDKQYN 1301 +G++ + G+ + I L+ G T ++ I ++ ++ Sbjct: 2556 SGIILLGSGGTPAPPRRKRRQTGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFH 2615 Query: 1302 DGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQ----- 1356 DG H V + + + VD++R +N T +EQ KK + GG+P Q Sbjct: 2616 DGREHSVHVERTRGIFTVQVDENRRYMQNLT---VEQ-PIEVKKLFVGGAPPEFQPSPLR 2671 Query: 1357 -YANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKP 1415 F GCI N V DF R + + C + Sbjct: 2672 NIPPFEGCIWNLVINSVPM-----DFARPVSFKNADIGRC-----------------AHQ 2709 Query: 1416 KASQNKKGGKSKD-APSWDPVALKLPERNTPRNSH--CHLSNSPRAIEHAYQYGGTANSR 1472 K +++ G + +PV TP +H C + P + + Q+G + NS Sbjct: 2710 KLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALLIGSKQFGLSRNSH 2769 Query: 1473 QEFEHLKGDFGAKSQFSIRL--RTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGH 1530 D K++ +I L RT + G++FY++ DF T+ L +G + +++G Sbjct: 2770 IAIAF--DDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLGS 2827 Query: 1531 KKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEA-TWKIKGPIYLGG 1589 K NDG WH + +R + G L +DG ++ P +A + G +Y+GG Sbjct: 2828 GDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDG--ASNRTISPKKADILDVVGMLYVGG 2885 Query: 1590 VAPGKAVKNVQINSIYSFSGCLSNLQL--NGASITSASQTFSVTPCFEGPMETGTYFSTE 1647 + + + YS GC+ NL + A + + +F V CF + GTYF Sbjct: 2886 LPINYTTRRIG-PVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFAN-AQRGTYFDGT 2943 Query: 1648 GGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIR 1707 G+ F +GL + FE R +++G L+ S + + + M + +++ V+NG Sbjct: 2944 -GFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFHVDNGAG 3002 Query: 1708 DFST--SVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNP--KPIDHREPVF 1763 F+ LCDG+WH++T + + ++L VD P NP D +PVF Sbjct: 3003 RFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSP-NPASTSADTNDPVF 3061 Query: 1764 VGGVPESLLTPRLAPSKPFTGCIRHFVI---DGHP--VSFSKAALVSGAVSINSCPA 1815 VGG P+ L L S PF GCIR + G P V+F+KA + G + SCPA Sbjct: 3062 VGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPV-SCPA 3117 Score = 175 bits (444), Expect = 3e-43 Identities = 88/216 (40%), Positives = 117/216 (54%), Gaps = 12/216 (5%) Query: 62 PAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121 P + N F G C PC C G++ C D +G C++C+ +T G +C+KCL G+ G+ Sbjct: 740 PRHRRVNGTIF---GGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEP 796 Query: 122 IRGAPQFCQPCPCPLPHLA-NFAESCY--RKNGAVRCICNENYAGPNCERCAPGYYGNPL 178 +G + CQPC CPL + NF+ +C+ R G + C Y GP CERCA GY+G P Sbjct: 797 TKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS 856 Query: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC 238 + G +C+ C C+ N D + I CD ++G C C TTG CE CA GY+GDA AKNC Sbjct: 857 VPGGSCQPCQCNDNLDFS-IPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNC 915 Query: 239 AVCNCGGG-----PCDSVTGECLEEGFEPPTGCDKC 269 C C G C S TG+C CDKC Sbjct: 916 QPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKC 951 Score = 132 bits (332), Expect = 3e-30 Identities = 79/223 (35%), Positives = 106/223 (47%), Gaps = 25/223 (11%) Query: 57 LGRLPPAAEKCNAGFFHTLS---GECVPCDCNGNSNECLDGS-----GYCVHCQRNTTGE 108 +G P E+C G+F S G C PC CN N + + GS G C+ C+ TTG Sbjct: 837 VGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGR 896 Query: 109 HCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCER 168 +CE C DGY GD++ + CQPC C +F+E C+ + G +C C N G C++ Sbjct: 897 YCELCADGYFGDAVDA--KNCQPCRCNAG--GSFSEVCHSQTG--QCECRANVQGQRCDK 950 Query: 169 CAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGY 228 C G +G L C C+C+ + DC+E +GQC C TG KC+RCA GY Sbjct: 951 CKAGTFG--LQSARGCVPCNCNSFGSKSF---DCEE-SGQCW-CQPGVTGKKCDRCAHGY 1003 Query: 229 YGDARIAKNCAVCNCG--GGPCDSVTGECLEEGFEPPTGCDKC 269 + C C C G CD TG C+ C KC Sbjct: 1004 FNFQE--GGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKC 1044 Score = 110 bits (275), Expect = 1e-23 Identities = 74/199 (37%), Positives = 98/199 (49%), Gaps = 30/199 (15%) Query: 65 EKCNAGFFHTLSGE-CVPCDCNGNSNECLD--GSGYCVHCQRNTTGEHCEKCLDGYIGDS 121 +KC AG F S CVPC+CN ++ D SG C CQ TG+ C++C GY Sbjct: 949 DKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQC-WCQPGVTGKKCDRCAHGYFNFQ 1007 Query: 122 IRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIG 181 G C C C HL N +C K G RCIC N G C +CAP +G+ + G Sbjct: 1008 EGG----CTACECS--HLGN---NCDPKTG--RCICPPNTIGEKCSKCAPNTWGHSITTG 1056 Query: 182 STCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVC 241 CK C+CS + +L F+ C+ TGQC NC +G KC C+ G++ R C +C Sbjct: 1057 --CKACNCS--TVGSLDFQ-CNVNTGQC-NCHPKFSGAKCTECSRGHWNYPR----CNLC 1106 Query: 242 NC-----GGGPCDSVTGEC 255 +C CDS T +C Sbjct: 1107 DCFLPGTDATTCDSETKKC 1125 Score = 102 bits (254), Expect = 3e-21 Identities = 63/200 (31%), Positives = 87/200 (43%), Gaps = 26/200 (13%) Query: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124 ++C G+F+ G C C+C+ N C +G C+ C NT GE C KC G SI Sbjct: 997 DRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCI-CPPNTIGEKCSKCAPNTWGHSITT 1055 Query: 125 APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184 C+ C C +F C G +C C+ ++G C C+ G++ P C Sbjct: 1056 G---CKACNCSTVGSLDF--QCNVNTG--QCNCHPKFSGAKCTECSRGHWNYP-----RC 1103 Query: 185 KKCDC------SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKN 237 CDC + D C + TGQC C N G C+RC PG +G DA+ Sbjct: 1104 NLCDCFLPGTDATTCDSETKKCSCSDQTGQC-TCKVNVEGIHCDRCRPGKFGLDAKNPLG 1162 Query: 238 CAVCNCGGGPCDSVTGECLE 257 C+ C C G T +C E Sbjct: 1163 CSSCYCFG-----TTTQCSE 1177 Score = 99.8 bits (247), Expect = 2e-20 Identities = 76/261 (29%), Positives = 105/261 (40%), Gaps = 48/261 (18%) Query: 69 AGFFHTLSGECVPCDCNGNSNECLD------------------GSGYCVHCQRNTTGEHC 110 AG F T + EC C+C+G + EC G G C++C +NT G +C Sbjct: 332 AGTFLTKT-ECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINC 390 Query: 111 EKCLDGYIGDSIRGAPQFCQPC-PCPLPHLANFAESCYRKNGAVR-------CICNENYA 162 E C DG+ +P + +PC PC + + E C + R C C + Sbjct: 391 ETCTDGFFRPK-GVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFG 449 Query: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCE 222 G +C+RCA GY G P CK C+CSG N D G C C N G C Sbjct: 450 GVSCDRCARGYTGYP-----DCKACNCSGLGSKNE-----DPCFGPC-ICKENVEGGDCS 498 Query: 223 RCAPGYYG-DARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTD---ALR 278 RC G++ K C C C G V+ C + D W LTD +R Sbjct: 499 RCKSGFFNLQEDNWKGCDECFCSG-----VSNRCQSSYWTYGKIQDMSGWYLTDLPGRIR 553 Query: 279 LAALSIEEGKSGVLSVSSGAA 299 +A + +S+S+ A Sbjct: 554 VAPQQDDLDSPQQISISNAEA 574 Score = 77.0 bits (188), Expect = 2e-13 Identities = 53/175 (30%), Positives = 72/175 (41%), Gaps = 42/175 (24%) Query: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRK----NGAV----------------------R 154 SI A + CQ CP + + ESC+ + NG + Sbjct: 716 SIAAAVEVCQ---CPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGE 772 Query: 155 CI-CNENYAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDC--DEVTGQ-C 209 C+ C ++ GP C++C PG+YG P C+ C C N N C D G C Sbjct: 773 CLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLIC 832 Query: 210 RNCLRNTTGFKCERCAPGYYGDARI-AKNCAVCNCGG-------GPCDSVTGECL 256 C TG +CERCA GY+G + +C C C G CDS++G CL Sbjct: 833 DGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCL 887 Score = 70.9 bits (172), Expect = 1e-11 Identities = 67/239 (28%), Positives = 91/239 (38%), Gaps = 58/239 (24%) Query: 82 CDCNGNSNEC-LD---GSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137 C C G++ C LD C C+ NT G+ C++C G+ R A F C Sbjct: 287 CICYGHARACPLDPATNKSRC-ECEHNTCGDSCDQCCPGFHQKPWR-AGTFLTKTECEAC 344 Query: 138 HLANFAESCY------RKN-----------GAVRCICNENYAGPNCERCAPGYY---GNP 177 + AE CY R+N G V C +N AG NCE C G++ G Sbjct: 345 NCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVS 404 Query: 178 LLIGSTCKKCDCSGNSDPNLIFEDCDE------VTGQCRNCLRNTTGFKCERCAPGYYGD 231 C+ C C N + ++ G C +C G C+RCA GY G Sbjct: 405 PNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSC-HCKTGFGGVSCDRCARGYTG- 462 Query: 232 ARIAKNCAVCNCGG----------GPC----DSVTGEC--LEEGF-----EPPTGCDKC 269 +C CNC G GPC + G+C + GF + GCD+C Sbjct: 463 ---YPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDEC 518 >gi|38788416 laminin, alpha 1 precursor [Homo sapiens] Length = 3075 Score = 394 bits (1011), Expect = e-109 Identities = 426/1830 (23%), Positives = 765/1830 (41%), Gaps = 214/1830 (11%) Query: 58 GRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117 G+LP +++ L CVPC CN +S+ C +G C++C NT G+HC+ C GY Sbjct: 1383 GKLPAGSDRGP----RPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGY 1438 Query: 118 IGDSIRGAPQFCQPCPCPLPHLANFAESCYRK-NGAVRC-ICNENYAGPNCERCAPGYYG 175 G + G+ C C CP A+F+ +C + + RC C Y G +CERC+ YYG Sbjct: 1439 YG-KVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYG 1497 Query: 176 NPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235 NP G +C+KCDC+ + + DCD +GQC C +G +C+ C P + + Sbjct: 1498 NPQTPGGSCQKCDCNPHGS---VHGDCDRTSGQC-VCRLGASGLRCDECEPRH---ILME 1550 Query: 236 KNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVS 295 +C C+ D G L + D + A LS+ +G++ V Sbjct: 1551 TDCVSCD------DECVGVLLND---------------LDEIGDAVLSL--NLTGIIPVP 1587 Query: 296 SGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQ 355 G + N N T YL ++ L E Q L KI++ +L + ++ + Sbjct: 1588 YGILS----NLENTTKYLQESLLKE-NMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQK 1642 Query: 356 ASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVL 415 +R + + KES D +L ++ +K +N + +E L P + + Sbjct: 1643 VNRATERIFKESQDLAIAIERLQMSITEIMEK-TTLNQTL----DEDFLLPNSTLQNMQQ 1697 Query: 416 AQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQ-AESWQRLHNETRTLFPVVLEQLDDY 474 L EI + F + E A +LLSQ E++Q+ E L L + Sbjct: 1698 NGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKH 1757 Query: 475 NAKLSDLQ------EALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLS 528 N +L + EA Q N++ + N + ++ H ++++ + ++ V L Sbjct: 1758 NNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLI 1817 Query: 529 TSADSLT-TPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHA 587 +A + T + L L+D A+I +L + +S + + DLV A DHA Sbjct: 1818 DAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQRNAV--DLVYRAEDHA 1875 Query: 588 QDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDA 647 + Q+ A+ L L ++ + A A+ V+ NI + + E+ E A A T Sbjct: 1876 AEFQRLADVLYSGL--ENIRNVSLNATSAAYVHYNIQSLIEESEELARDAHRTVTETSLL 1933 Query: 648 VSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSD 707 + + S L + L K + E +++ + + + ++ Sbjct: 1934 SESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALE-LSELRNKTNRFQENAVEITRQTNE 1992 Query: 708 AVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAY 767 ++ L+A +G + + +++ + A+++ + + A ++ L N S +L +++ Sbjct: 1993 SLLILRAIPKG-IRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLR 2051 Query: 768 NT---------AVNSARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQT 818 T A A V+++ L D+L+ + K N+S ++ I+ LI+Q Sbjct: 2052 ETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPL--KMLEENLSRNLSEIKLLISQA 2109 Query: 819 RSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYL 878 R A+ I+V++ D + S + + +L+L +K T+ D + YL Sbjct: 2110 RKQAASIKVAVSADRDCIRAYQPQISSTN---YNTLTLNVK--------TQEPDNLLFYL 2158 Query: 879 GSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPV--SSWPAYFSIVKIERVGKHG 936 GS A +++ + ++ + ++++LG+ + P+ + W + + + R G G Sbjct: 2159 GSSTA-SDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHS----IHVARFGNIG 2213 Query: 937 KVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFV 996 L+V +SS ++ K + G ++LD++ T+ +VGG+ K ++ + F Sbjct: 2214 S--LSVKEMSSN-QKSPTKTSKSPGTANVLDVN-NSTLMFVGGLGGQIKKSPAVKVTHFK 2269 Query: 997 GCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDI 1056 GCL A LN I L+N+ R +Q+ S+ FDGSGY+VV Sbjct: 2270 GCLGEAFLNGKSIGLWNYIEREGK--------CRGCFGSSQNEDPSFHFDGSGYSVV--- 2318 Query: 1057 TRRGKFGQVTRFDIEVRTPADNGLILLM--VNGSMFFRLEMRNGYLHVFYDFGFSGGPVH 1114 + VT+ + T + NGL+L + F +E+ G + V D G GP+ Sbjct: 2319 -EKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLG--SGPIT 2375 Query: 1115 LEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKIPFTD--------- 1165 L L + N+ +++I+ + + ++ V+D + + + ++ + P Sbjct: 2376 L---LTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLDKD 2432 Query: 1166 -IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYGCPEDS 1224 IY+GG P +SR +R + +F GC+K + + F+LL + GV GC + Sbjct: 2433 PIYVGGLP----RSRVVRRGVTTK-SFVGCIKNLEISRSTFDLLR--NSYGVRKGCLLEP 2485 Query: 1225 LISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDV---------- 1274 + R F +I K S E F T +G++ A G DV Sbjct: 2486 I--RSVSFLKGGYIELPPK-SLSPESEWLVTFATTNSSGIIL-AALGGDVEKRGDREEAH 2541 Query: 1275 ---FSISLDNGTVIMDVK-----GIK---VQSVDKQYNDGLSHFVISSVSPTRYELIVDK 1323 FS+ L G + + V G++ + + +DG +H S+S R I+ Sbjct: 2542 VPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAH----SISLVRNRRII-T 2596 Query: 1324 SRVGSKNPTKGK----IEQTQASEKKFYFGGSP------ISAQYANFTGCISNAYFTRVD 1373 ++ NP + K +E + Y GG P + +F GCI N F Sbjct: 2597 VQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMRRSFHGCIKNLIF---- 2652 Query: 1374 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD 1433 ++E+ DF L C + +PK + + + K P Sbjct: 2653 -NLELLDFNSAVGHEQVDLDTCWLS--------------ERPKLAPDAEDSKLLPEPRAF 2697 Query: 1434 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR 1493 P C + + + A+Q+G T NS + K + +R Sbjct: 2698 P-------------EQCVVDAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKLSVELSIR 2744 Query: 1494 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR 1553 T +S G+I+Y++ Q + D+ L L GRL +MF++G + K+ +DG WH V Sbjct: 2745 TFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDY 2804 Query: 1554 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN 1613 + G + +DG ++ ++G YLGG+ + + N +S C+ + Sbjct: 2805 VKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIG-NITHSIPACIGD 2863 Query: 1614 LQLNGASITSAS--QTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRP 1671 + +N + S F+V C+ E GTYF G ++ E + + I E R Sbjct: 2864 VTVNSKQLDKDSPVSAFTVNRCYAVAQE-GTYFDGSGYAALVKEGYKVQSDVNITLEFRT 2922 Query: 1672 RSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQS--LCDGRWHRITV 1729 S +G L+ + + + + + +G+V+ VNNG + + PK + LCDG+WH + Sbjct: 2923 SSQNGVLLGISTAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQA 2982 Query: 1730 IRDSNVVQLDVDSEVNHVVGP-LNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRH 1788 + + + L VD P +D P++VGG P + L F GC+R Sbjct: 2983 NKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRK 3042 Query: 1789 FVIDGHP----VSFSKAALVSGAVSINSCP 1814 + P FS+A + G V ++SCP Sbjct: 3043 LALIKSPQVQSFDFSRAFELHG-VFLHSCP 3071 Score = 199 bits (505), Expect = 3e-50 Identities = 103/248 (41%), Positives = 133/248 (53%), Gaps = 14/248 (5%) Query: 35 DIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHT----LSGECVPCDCNGNSNE 90 DI S+A+ + G + E C +G++ G C PC+C+G++ E Sbjct: 691 DIASSNAIDLVVAADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAE 750 Query: 91 CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLAN-FAESCYRK 149 C + G C+ C NTTG HCE+CL G+ G+ RG P CQPC CPL +N F+ +C+ Sbjct: 751 C-NVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLN 809 Query: 150 NG--AVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTG 207 +G V C Y+G CERCA GYYGNP + G +C CDCSGN DP+ CD VTG Sbjct: 810 DGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGH-CDSVTG 868 Query: 208 QCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC-----GGGPCDSVTGECLEEGFEP 262 +C CL NT G CERCA G+YGDA AKNC C C C TG C + Sbjct: 869 ECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVT 928 Query: 263 PTGCDKCV 270 CD+C+ Sbjct: 929 GQQCDQCL 936 Score = 127 bits (318), Expect = 1e-28 Identities = 74/215 (34%), Positives = 110/215 (51%), Gaps = 25/215 (11%) Query: 65 EKCNAGFFH--TLSGE-CVPCDCNGN-----SNECLDGSGYCVHCQRNTTGEHCEKCLDG 116 E+C G++ T+ GE CVPCDC+GN + C +G C+ C NT G HCE+C DG Sbjct: 829 ERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADG 888 Query: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176 + GD++ + C+ C C + + + C+ + G C C N G C++C GYYG Sbjct: 889 FYGDAVTA--KNCRACECHVK--GSHSAVCHLETGL--CDCKPNVTGQQCDQCLHGYYG- 941 Query: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK 236 L G C+ C+CS + + C + GQC +C+ G +C+RCA G+Y A Sbjct: 942 -LDSGHGCRPCNCSVAGS---VSDGCTD-EGQC-HCVPGVAGKRCDRCAHGFY--AYQDG 993 Query: 237 NCAVCNC--GGGPCDSVTGECLEEGFEPPTGCDKC 269 +C C+C CD TGEC+ C++C Sbjct: 994 SCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEEC 1028 Score = 90.5 bits (223), Expect = 1e-17 Identities = 59/197 (29%), Positives = 83/197 (42%), Gaps = 43/197 (21%) Query: 79 CVPCDCNGNSNEC------------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120 C C+C+ + +C G G C++C +NT G +CE C+DGY Sbjct: 324 CEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRP 383 Query: 121 SIRGAPQFCQPC-PCPLPHLANFAESCYR-------KNGAV--RCICNENYAGPNCERCA 170 + +P +PC PC + + + C + NG +C C E Y G C+RC Sbjct: 384 H-KVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQ 442 Query: 171 PGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDE-VTGQCRNCLRNTTGFKCERCAPGYY 229 GY P TC C C N + DE TG C C N G C+RC PG+Y Sbjct: 443 LGYKDYP-----TCVSCGC------NPVGSASDEPCTGPC-VCKENVEGKACDRCKPGFY 490 Query: 230 G-DARIAKNCAVCNCGG 245 + + C+ C C G Sbjct: 491 NLKEKNPRGCSECFCFG 507 Score = 90.5 bits (223), Expect = 1e-17 Identities = 62/188 (32%), Positives = 78/188 (41%), Gaps = 21/188 (11%) Query: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124 ++C GF+ G C PCDC N C +G CV C +T G CE+C DG+ G Sbjct: 981 DRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECV-CPPHTQGVKCEECEDGHWG---YD 1036 Query: 125 APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184 A CQ C C L + + C G C C + G C++C+ GY P C Sbjct: 1037 AEVGCQACNCSL--VGSTHHRCDVVTG--HCQCKSKFGGRACDQCSLGYRDFP-----DC 1087 Query: 185 KKCDCS--GNSDPNLIFED----CDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKN 237 CDC G S E C E TG C C N G +C C G + A Sbjct: 1088 VPCDCDLRGTSGDACNLEQGLCGCVEETGAC-PCKENVFGPQCNECREGTFALRADNPLG 1146 Query: 238 CAVCNCGG 245 C+ C C G Sbjct: 1147 CSPCFCSG 1154 Score = 73.2 bits (178), Expect = 2e-12 Identities = 64/227 (28%), Positives = 87/227 (38%), Gaps = 50/227 (22%) Query: 82 CDCNGNSNEC-LDGSGYCVHCQ--RNTTGEHCEKCLDGYIGDSIR----GAPQFCQPCPC 134 C C G+++ C D + + CQ NT GE C +C GY R + C+ C C Sbjct: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329 Query: 135 PLPHLANFAESCYR-----------------KNGAVRCICNENYAGPNCERCAPGYYGNP 177 N A+ CY + G V C +N G NCE C GYY P Sbjct: 330 -----HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYY-RP 383 Query: 178 LLIG----STCKKCDCS--GNSDPNLIFEDC------DEVTGQCRNCLRNTTGFKCERCA 225 + C+ C+C G+ I +D + GQC C TG KC+RC Sbjct: 384 HKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQC-PCKEGYTGEKCDRCQ 442 Query: 226 PGYYGDARIAKNCAVCNC---GGGPCDSVTGECLEEGFEPPTGCDKC 269 GY + C C C G + TG C+ + CD+C Sbjct: 443 LGY----KDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACDRC 485 >gi|167614504 laminin, beta 1 precursor [Homo sapiens] Length = 1786 Score = 171 bits (434), Expect = 5e-42 Identities = 100/280 (35%), Positives = 137/280 (48%), Gaps = 34/280 (12%) Query: 21 CSRAASGD-----DNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTL 75 C+R A G P + +V P T + G ++C G H Sbjct: 803 CNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPG--HWG 860 Query: 76 SGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP 135 C PC CNG++++C +G C++CQ T G +CE+CL GY GD I G+ C+PCPCP Sbjct: 861 FPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCP 920 Query: 136 --LPHLANFAESCYRKNGAVR--CICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSG 191 FA SCY+ ++ C+C+ Y G C+ CA GY+GNP +G +C+ C C Sbjct: 921 DGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHN 980 Query: 192 N---SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC--AVCN---- 242 N +DP E CD+ TG+C CL +T G C+ C GYYGDA + ++C VCN Sbjct: 981 NIDTTDP----EACDKETGRCLKCLYHTEGEHCQFCRFGYYGDA-LQQDCRKCVCNYLGT 1035 Query: 243 ----CGGG--PCDSVTGECLEEGFEPPTGCDKC---VWDL 273 C G CD TG+CL CD+C W L Sbjct: 1036 VQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQL 1075 Score = 142 bits (359), Expect = 2e-33 Identities = 180/820 (21%), Positives = 328/820 (40%), Gaps = 120/820 (14%) Query: 58 GRLPPAAEKCNAGFFHTLS---GECVPCDCNGNSNE-----CLDGSGYCVHCQRNTTGEH 109 G + + C +G+F S G C PC C+ N + C +G C+ C +T GEH Sbjct: 949 GYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEH 1008 Query: 110 CEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKN-----GAVRCICNENYAGP 164 C+ C GY GD+++ Q C+ C C +L E C + +C+C N G Sbjct: 1009 CQFCRFGYYGDALQ---QDCRKCVCN--YLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQ 1063 Query: 165 NCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224 NC+RCAP + L G+ C C+C+ + C+E TGQC+ C+ G C C Sbjct: 1064 NCDRCAPNTW--QLASGTGCDPCNCNA---AHSFGPSCNEFTGQCQ-CMPGFGGRTCSEC 1117 Query: 225 APGYYGDARIAKNCAVCNCGGG-----PCDSVTGECL-EEGFEPPTGCDKCVWDLTDALR 278 ++GD + C C+C CD TG+C+ EG E P CDKC Sbjct: 1118 QELFWGDPDV--ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPR-CDKCT-------- 1166 Query: 279 LAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYA--LRKIQINNAE 336 G SGV + ++ A ++ +L+ R +++ + ++I+ Sbjct: 1167 -------RGYSGVFPDCTPC------HQCFALWDVIIAELTNRTHRFLEKAKALKISGVI 1213 Query: 337 NTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKML 396 + + VE V + K L Q + + + + L E+A + + E+ ++ Sbjct: 1214 GPYRETVDSVERKVSEI-----KDILAQSPAAEPLKNIGNLFEEAEKLIKDVTEMMAQV- 1267 Query: 397 YYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVD---EEADEAYELLSQAESW 453 ++S+ + +E+ S Q T+ E +D +E E E + ++ Sbjct: 1268 ---------EVKLSDTTSQSNSTAKELDSLQ---TEAESLDNTVKELAEQLEFIKNSDIR 1315 Query: 454 QRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQ 513 L + T+ F + LE + NA ++ ++Q+ ED+ ++ ++ +++Q Sbjct: 1316 GALDSITK-YFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQ 1374 Query: 514 ERVREQM--EVVNMSLSTSADSL--TTPRLTLSELDDIIKNASGIYAEID-GAKSELQVK 568 R+ +++ ++ ++ LS +A+ T P + SE + G D G + Sbjct: 1375 ARLLDELAGKLQSLDLSAAAEMTCGTPPGASCSETE-----CGGPNCRTDEGERKCGGPG 1429 Query: 569 LSNLSNLSHDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVS 628 L ++H+ Q+A+D QD+ L A E + VS Sbjct: 1430 CGGLVTVAHNAWQKAMDLDQDV-----------------------LSALAEVEQLSKMVS 1466 Query: 629 EANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQAREL--QAKAESSSDEAVAD 686 EA A+ A + + I + ++ +E NL+ Q R Q A+ S EAVA+ Sbjct: 1467 EAKLRADEAKQSAEDILLKTNATKEKMDKSNEELRNLIKQIRNFLTQDSADLDSIEAVAN 1526 Query: 687 --TSRRVGGALARKSALKTRLSDAVKQLQAAE--RGDAQQRLGQSRLITEEANRTTMEVQ 742 + + L + + V+ L E + + ++ ++ EEA R + Sbjct: 1527 EVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASKSAT 1586 Query: 743 --QATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTV-EQKR 799 + TA M ++ Q A A + LT + + T+ + Sbjct: 1587 DVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLFNASQ 1646 Query: 800 PASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEV 839 S + +++ ++ AQ A I+ + QSA +V Sbjct: 1647 RISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDV 1686 Score = 113 bits (282), Expect = 2e-24 Identities = 62/174 (35%), Positives = 81/174 (46%), Gaps = 21/174 (12%) Query: 76 SGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP 135 +G CD G+ + D +G C+ N G C +C G G P C+PC C Sbjct: 769 TGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFG----FGPSGCKPCECH 824 Query: 136 LPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDP 195 L N C G +C C + C+RC PG++G P +C+ C C+G++D Sbjct: 825 LQGSVN--AFCNPVTG--QCHCFQGVYARQCDRCLPGHWGFP-----SCQPCQCNGHAD- 874 Query: 196 NLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK--NCAVCNCGGGP 247 DCD VTG+C NC T G CERC GYYGD I +C C C GP Sbjct: 875 -----DCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGP 923 Score = 93.6 bits (231), Expect = 2e-18 Identities = 77/241 (31%), Positives = 110/241 (45%), Gaps = 52/241 (21%) Query: 82 CDCNGNSNEC--LDG---------SGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP---- 126 C C G+++EC +DG G+C+ C+ NT G +CE C+D Y R A Sbjct: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329 Query: 127 QFCQPCPCPLPHLA-NFAESCY----RKNGAVRCICNENYAGPNCERCAPGYYGNP---L 178 C+ C C ++ +F + Y +G V C N G NCE+C P YY +P + Sbjct: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDI 389 Query: 179 LIGSTCKKCDC--SGNSDPNLIFEDCDEVT--------GQCRNCLRNTTGFKCERCAPGY 228 + C++C C +G+ + + CD T GQCR C N G C+ C G+ Sbjct: 390 RDPNFCERCTCDPAGSQNEGI----CDSYTDFSTGLIAGQCR-CKLNVEGEHCDVCKEGF 444 Query: 229 YG----DARIAKNCAVCN-----CGGGPCDSVTGECLEEGFEPPTGCDKCV---WDLTDA 276 Y D K+CA CN GG PCDS TG C + CD+C+ W L++ Sbjct: 445 YDLSSEDPFGCKSCA-CNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSND 503 Query: 277 L 277 L Sbjct: 504 L 504 Score = 83.2 bits (204), Expect = 2e-15 Identities = 62/205 (30%), Positives = 83/205 (40%), Gaps = 29/205 (14%) Query: 76 SGECVPCDCNGNSNEC-LD----------GSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124 S C C+CN +S C D G C CQ NT G +CE+C Y R Sbjct: 329 SNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERD 388 Query: 125 A--PQFCQPCPCPLPHLANFAESCYRKNG------AVRCICNENYAGPNCERCAPGYYGN 176 P FC+ C C P + C A +C C N G +C+ C G+Y Sbjct: 389 IRDPNFCERCTCD-PAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDL 447 Query: 177 PLLIGSTCKKCDCSG-NSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235 CK C C+ + P CD TG C C R TG C++C P ++G + Sbjct: 448 SSEDPFGCKSCACNPLGTIPG--GNPCDSETGHCY-CKRLVTGQHCDQCLPEHWGLSNDL 504 Query: 236 KNCAVCNC--GG---GPCDSVTGEC 255 C C+C GG C + +G+C Sbjct: 505 DGCRPCDCDLGGALNNSCFAESGQC 529 Score = 82.8 bits (203), Expect = 3e-15 Identities = 44/120 (36%), Positives = 60/120 (50%), Gaps = 14/120 (11%) Query: 154 RCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCL 213 +C C N G C RCAPG +G S CK C+C N C+ VTGQC +C Sbjct: 791 QCQCRPNVVGRTCNRCAPGTFG---FGPSGCKPCECHLQGSVNAF---CNPVTGQC-HCF 843 Query: 214 RNTTGFKCERCAPGYYGDARIAKNCAVCNCGG--GPCDSVTGECLE-EGFEPPTGCDKCV 270 + +C+RC PG++G +C C C G CD VTGECL + + C++C+ Sbjct: 844 QGVYARQCDRCLPGHWG----FPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCL 899 Score = 68.6 bits (166), Expect = 5e-11 Identities = 50/161 (31%), Positives = 69/161 (42%), Gaps = 25/161 (15%) Query: 82 CDCNGNSNECLDGS----------GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQP 131 CD G+ NE + S G C C+ N GEHC+ C +G+ D P C+ Sbjct: 400 CDPAGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFY-DLSSEDPFGCKS 457 Query: 132 CPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG--NPLLIGSTCKKCD 188 C C PL + C + G C C G +C++C P ++G N L C+ CD Sbjct: 458 CACNPLGTIPG-GNPCDSETG--HCYCKRLVTGQHCDQCLPEHWGLSNDL---DGCRPCD 511 Query: 189 CSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229 C N C +GQC +C + G +C PGYY Sbjct: 512 CDLGGALN---NSCFAESGQC-SCRPHMIGRQCNEVEPGYY 548 Score = 67.0 bits (162), Expect = 2e-10 Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 15/116 (12%) Query: 67 CNAGFFHTLSGE---CVPCDCNG-----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYI 118 C GF+ S + C C CN N C +G+C +C+R TG+HC++CL + Sbjct: 440 CKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHC-YCKRLVTGQHCDQCLPEHW 498 Query: 119 GDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174 G + C+PC C L N SC+ ++G +C C + G C PGYY Sbjct: 499 G--LSNDLDGCRPCDCDLGGALN--NSCFAESG--QCSCRPHMIGRQCNEVEPGYY 548 >gi|143770880 laminin, beta 4 [Homo sapiens] Length = 1761 Score = 164 bits (416), Expect = 6e-40 Identities = 91/233 (39%), Positives = 121/233 (51%), Gaps = 33/233 (14%) Query: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124 ++C AG+F S C PC CN + C +G C +C TTG +CE+C+DGY G+ G Sbjct: 848 DRCLAGYFGFPS--CHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSG 905 Query: 125 APQFCQPCPCPLPHLAN--FAESCYRK--NGAVRCICNENYAGPNCERCAPGYYGNPLLI 180 P C+PC CP +N FA SCY+ + V C C + Y G C C+ G+YGNP + Sbjct: 906 QP--CRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRIS 963 Query: 181 GSTCKKCDCSGN---SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN 237 G+ C+ C C+ N +DP E C VTG+C CL NT G C+ C PG+YG A + + Sbjct: 964 GAPCQPCACNNNIDVTDP----ESCSRVTGECLRCLHNTQGANCQLCKPGHYGSA-LNQT 1018 Query: 238 CAVCNC------------GGGP--CDSVTGECLEEGFEPPTGCDKCV---WDL 273 C C+C GGG CD VTG C CD+C W+L Sbjct: 1019 CRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNL 1071 Score = 109 bits (273), Expect = 2e-23 Identities = 66/201 (32%), Positives = 88/201 (43%), Gaps = 28/201 (13%) Query: 79 CVPCDCNGNSNEC------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIR--G 124 C C CN +S+ C L G G C CQ NT G+HC++C + D ++ Sbjct: 329 CRSCSCNSHSSRCHFDMTTYLASGGLSG-GVCEDCQHNTEGQHCDRCRPLFYRDPLKTIS 387 Query: 125 APQFCQPCPCPLPHLANFAESCYRKNGAV-----RCICNENYAGPNCERCAPGYYGNPLL 179 P C PC C + + A+ +C+C EN G C++C P +YG Sbjct: 388 DPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSAT 447 Query: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCA 239 C+ CDC N +L F CD TGQC CL TG CE C GY+G C+ Sbjct: 448 DPLGCQPCDC--NPLGSLPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWGLGNHLHGCS 504 Query: 240 VCNC--GG---GPCDSVTGEC 255 C+C GG C G+C Sbjct: 505 PCDCDIGGAYSNVCSPKNGQC 525 Score = 91.3 bits (225), Expect = 8e-18 Identities = 76/243 (31%), Positives = 103/243 (42%), Gaps = 54/243 (22%) Query: 82 CDCNGNSNEC-----LDGS---------GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQ 127 C CNG+++EC + G G CV CQ NT G +CE+C D + R A Sbjct: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAPWRPAAD 323 Query: 128 F----CQPCPC-PLPHLANFAESCYRKNGAVR---C-ICNENYAGPNCERCAPGYYGNPL 178 C+ C C +F + Y +G + C C N G +C+RC P +Y +PL Sbjct: 324 LQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPL 383 Query: 179 LIGS---TCKKCDCS-----------GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224 S C C+C +SDP L V GQC C N G KC++C Sbjct: 384 KTISDPYACIPCECDPDGTISGGICVSHSDPAL-----GSVAGQCL-CKENVEGAKCDQC 437 Query: 225 APGYYG-DARIAKNCAVCNC---GGGP---CDSVTGECLEEGFEPPTGCDKCV---WDLT 274 P +YG A C C+C G P CD TG+CL + C++C W L Sbjct: 438 KPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLG 497 Query: 275 DAL 277 + L Sbjct: 498 NHL 500 Score = 90.5 bits (223), Expect = 1e-17 Identities = 61/192 (31%), Positives = 78/192 (40%), Gaps = 25/192 (13%) Query: 60 LPPAAEKCNAGFFHTLSGECVPCDCNGNSN---ECLDGSGYCVHCQRNTTGEHCEKCLDG 116 LP A E+ L V C C+ + C G C C+ G C++C G Sbjct: 747 LPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQC-QCKPLVVGRCCDRCSTG 805 Query: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAES-CYRKNGAVRCICNENYAGPNCERCAPGYYG 175 G C PC C H ++ C + G +C C+ +G C+RC GY+G Sbjct: 806 SYDLGHHG----CHPCHC---HPQGSKDTVCDQVTG--QCPCHGEVSGRRCDRCLAGYFG 856 Query: 176 NPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235 P +C C C N E CD TG C NC TTG CERC GYYG+ Sbjct: 857 FP-----SCHPCPC------NRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSG 905 Query: 236 KNCAVCNCGGGP 247 + C C C P Sbjct: 906 QPCRPCLCPDDP 917 Score = 85.1 bits (209), Expect = 6e-16 Identities = 58/187 (31%), Positives = 81/187 (43%), Gaps = 26/187 (13%) Query: 67 CNAGFFHT-LSGECVPCDCNGNS---NECLDGSGYCV--------HCQRNTTGEHCEKCL 114 C G + + L+ C C C+ + EC G G C+ C N TG C++C Sbjct: 1006 CKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCA 1065 Query: 115 DGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174 DGY + + G + CQ C C P + + C + G +C C Y G C C YY Sbjct: 1066 DGY-WNLVPG--RGCQSCDCD-PRTSQ-SSHCDQLTG--QCPCKLGYGGKRCSECQENYY 1118 Query: 175 GNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARI 234 G+P C CDC+ I CD TG CR C +G +C+RCA G+ + Sbjct: 1119 GDP---PGRCIPCDCNRAGTQKPI---CDPDTGMCR-CREGVSGQRCDRCARGHSQEFPT 1171 Query: 235 AKNCAVC 241 C +C Sbjct: 1172 CLQCHLC 1178 Score = 67.0 bits (162), Expect = 2e-10 Identities = 49/155 (31%), Positives = 65/155 (41%), Gaps = 21/155 (13%) Query: 36 IEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNA------GFFHTLSGECVPCDCNGNSN 89 I G V DP S L + KC+ G T C PCDCN + Sbjct: 403 ISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGS 462 Query: 90 ----ECLDGSGYCVHCQRNTTGEHCEKCLDGY--IGDSIRGAPQFCQPCPCPLPHLANFA 143 C +G C+ C TG HCE+C GY +G+ + G C PC C + ++ Sbjct: 463 LPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWGLGNHLHG----CSPCDCDIG--GAYS 515 Query: 144 ESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 178 C KNG +C C + G +C APGY+ PL Sbjct: 516 NVCSPKNG--QCECRPHVTGRSCSEPAPGYFFAPL 548 Score = 66.2 bits (160), Expect = 3e-10 Identities = 52/191 (27%), Positives = 71/191 (37%), Gaps = 46/191 (24%) Query: 154 RCICNENYAGPNCERCAPGYYGNPL-----LIGSTCKKCDCSGNS-----DPNLIFEDCD 203 +C+C N GPNCERC + P L + C+ C C+ +S D Sbjct: 294 QCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGG 353 Query: 204 EVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN----CAVCNC------GGGPC----- 248 G C +C NT G C+RC P +Y D + C C C GG C Sbjct: 354 LSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSD 413 Query: 249 ---DSVTGECL-EEGFE-----------------PPTGCDKCVWDLTDALRLAALSIEEG 287 SV G+CL +E E P GC C + +L ++ G Sbjct: 414 PALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTG 473 Query: 288 KSGVLSVSSGA 298 + LS +GA Sbjct: 474 QCLCLSYVTGA 484 Score = 45.8 bits (107), Expect = 4e-04 Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 10/107 (9%) Query: 20 ACSRAASGDDNAFP------FDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFH 73 AC R A G N P D + ++ T + LG +C ++ Sbjct: 1060 ACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYG 1119 Query: 74 TLSGECVPCDCNGNSNE---CLDGSGYCVHCQRNTTGEHCEKCLDGY 117 G C+PCDCN + C +G C C+ +G+ C++C G+ Sbjct: 1120 DPPGRCIPCDCNRAGTQKPICDPDTGMC-RCREGVSGQRCDRCARGH 1165 Score = 42.4 bits (98), Expect = 0.004 Identities = 28/95 (29%), Positives = 39/95 (41%), Gaps = 13/95 (13%) Query: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240 G+ KC G+ + C + GQC+ C G C+RC+ G Y C Sbjct: 765 GAVACKCHPQGS-----VGSSCSRLGGQCQ-CKPLVVGRCCDRCSTGSYDLGH--HGCHP 816 Query: 241 CNCG-----GGPCDSVTGECLEEGFEPPTGCDKCV 270 C+C CD VTG+C G CD+C+ Sbjct: 817 CHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCL 851 >gi|145309326 laminin, gamma 1 precursor [Homo sapiens] Length = 1609 Score = 159 bits (401), Expect = 3e-38 Identities = 191/849 (22%), Positives = 329/849 (38%), Gaps = 180/849 (21%) Query: 79 CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP--- 135 CV C CNG+S C +G C +C+ NT G HCEKC DGY GDS G CQPCPCP Sbjct: 721 CVLCACNGHSETCDPETGVC-NCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGS 779 Query: 136 ----LPHLANFA-------------ESC--------YRKNGAVR----CICNENY----- 161 +P E C +NG VR C C++N Sbjct: 780 SCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAV 839 Query: 162 -----------------AGPNCERCAPGYYGNPLLIGST--CKKCDCS--GNSDPNLIFE 200 AG C+RC G++GNPL CK C+C+ G Sbjct: 840 GNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQ---S 896 Query: 201 DCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC-----GGGPCDSVTGEC 255 C+ VTGQC CL + TG C C PG+Y + + + C C+C G CD TG+C Sbjct: 897 SCNPVTGQCE-CLPHVTGQDCGACDPGFY-NLQSGQGCERCDCHALGSTNGQCDIRTGQC 954 Query: 256 LEE----------------GFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAA 299 + GF P GC C D +LS++ G G Sbjct: 955 ECQPGITGQHCERCEVNHFGF-GPEGCKPC-----DCHPEGSLSLQCKDDGRCECREGFV 1008 Query: 300 AHR---------------HVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLS 344 +R E A L+K K+++ ++++ E+ + +L + Sbjct: 1009 GNRCDQCEENYFYNRSWPGCQECPACYRLVKDKVAD-------HRVKLQELESLIANLGT 1061 Query: 345 DVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHEL 404 E + ++ + K ++E MD + A + + ++ D++Q +NN + + Sbjct: 1062 GDEMVTDQAFEDRLKE--AEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQN 1119 Query: 405 SPKEISEKLVLAQKMLEEIRSRQPF--FTQRELVDEEADEAYELLSQAES------WQRL 456 I E LA++ + + + REL + A ++Q ES L Sbjct: 1120 IRNTIEETGNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLL 1179 Query: 457 HNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVR-----------DAEDMNRATAAR 505 E R L ++ DD + +A N + + E++NR Sbjct: 1180 AEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQA 1239 Query: 506 Q---RDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDD--IIKNASGIYAEIDG 560 + +D EKQ RV E+ + A + LS LD + A+ I E + Sbjct: 1240 KNISQDLEKQAARVHEEAK----RAGDKAVEIYASVAQLSPLDSETLENEANNIKMEAEN 1295 Query: 561 AKSELQVKLSNLSNLSHDL------VQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKAL 614 + + KL + +L D+ V+ ++ + QQ A++L + ++ KAL Sbjct: 1296 LEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAA-------KAL 1348 Query: 615 DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQA 674 EA + L + I + + D ++ +K +E L + + Sbjct: 1349 ------------AEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAIN- 1395 Query: 675 KAESSSDEAVADTSRRVGGALARKSALKT------RLSDAVKQLQAAERGDAQQRLGQSR 728 + + ++E + + +G A A + K R++ AV++ + + +A++ + Sbjct: 1396 QTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVT 1455 Query: 729 LITEEANRTTMEVQQATAPMANNLTNWSQNLQ---HFDSSAYNTAVNS--ARDAVRNLTE 783 + E N ++Q+A + + Q++ +A +N+ A+++V +L Sbjct: 1456 DLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLLS 1515 Query: 784 VVPQLLDQL 792 ++ LL+QL Sbjct: 1516 IINDLLEQL 1524 Score = 115 bits (289), Expect = 3e-25 Identities = 62/181 (34%), Positives = 88/181 (48%), Gaps = 28/181 (15%) Query: 76 SGECVPCDCNGNSNECL---------DGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126 + EC+PCDCNG S EC G+C +CQ NT G HCE+C + + G Sbjct: 336 ASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFR---LGNN 392 Query: 127 QFCQPCPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCK 185 + C C C P+ L+ +S RC C G C+RC PG++ L + C+ Sbjct: 393 EACSSCHCSPVGSLSTQCDS------YGRCSCKPGVMGDKCDRCQPGFHS---LTEAGCR 443 Query: 186 KCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCG 244 C C DP+ ++C+ TG+C C N GF CERC PG++ ++ + C C C Sbjct: 444 PCSC----DPSGSIDECNIETGRC-VCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCF 498 Query: 245 G 245 G Sbjct: 499 G 499 Score = 103 bits (257), Expect = 2e-21 Identities = 65/187 (34%), Positives = 88/187 (47%), Gaps = 32/187 (17%) Query: 101 CQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNEN 160 C G+ CE CL GY R P PC L +E+C + G C C +N Sbjct: 692 CPVGYGGQFCEMCLSGY----RRETPNLGPYSPCVLCACNGHSETCDPETGV--CNCRDN 745 Query: 161 YAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGF 219 AGP+CE+C+ GYYG+ S C+ C C G S ++ + + V C NC TTG Sbjct: 746 TAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVV---CTNCPTGTTGK 802 Query: 220 KCERCAPGYYGDARIAKN-----CAVCNCGG-------GPCDSVTGECLE-----EGFEP 262 +CE C GY+GD + +N C +C C G C+ +TGECL+ GF Sbjct: 803 RCELCDDGYFGDP-LGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFY- 860 Query: 263 PTGCDKC 269 CD+C Sbjct: 861 ---CDRC 864 Score = 96.7 bits (239), Expect = 2e-19 Identities = 159/821 (19%), Positives = 312/821 (38%), Gaps = 152/821 (18%) Query: 67 CNAGFFHTLSGE-CVPCDCN--GNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 122 C+ GF++ SG+ C CDC+ G++N +C +G C CQ TG+HCE+C + G Sbjct: 919 CDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQC-ECQPGITGQHCERCEVNHFG--- 974 Query: 123 RGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGS 182 P+ C+PC C H + +G RC C E + G C++C Y+ N G Sbjct: 975 -FGPEGCKPCDC---HPEGSLSLQCKDDG--RCECREGFVGNRCDQCEENYFYNRSWPG- 1027 Query: 183 TCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARI---AKNCA 239 C++C C R D R+ Sbjct: 1028 -CQECPA-------------------------------CYRLVKDKVADHRVKLQELESL 1055 Query: 240 VCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAA 299 + N G G + VT + E+ + + ++ D LR A +++ ++ Sbjct: 1056 IANLGTGD-EMVTDQAFEDRLK------EAEREVMDLLR-EAQDVKDVDQNLMD-----R 1102 Query: 300 AHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRK 359 R N +++ I L+ + E L + + ENT + L+ +EK A+ Sbjct: 1103 LQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVENT-ERLIEIASRELEKAKVAAAN 1161 Query: 360 GQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKM 419 + Q ES N+ + L E+A + ++ ++ + ++ + + E L Sbjct: 1162 VSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLL------ 1215 Query: 420 LEEIRSRQPFFTQRELVDEEADEAYELLSQAESW-QRLHNETRTLFPVVLEQLDDYNAKL 478 L + + E ++ + ++A + E R+H E + +E A+L Sbjct: 1216 LRTLAGENQTAFEIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASV-AQL 1274 Query: 479 SDL-QEALDQALNYVR-DAEDMNRATAARQRDHEKQQERVR-EQMEVVNMSLSTSADSLT 535 S L E L+ N ++ +AE++ + + +D+E +E +R +++EV N+ + T Sbjct: 1275 SPLDSETLENEANNIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQT 1334 Query: 536 TPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEAN 595 A + A D AK+ L +EA +D QEAN Sbjct: 1335 ---------------ADQLLARADAAKA---------------LAEEAAKKGRDTLQEAN 1364 Query: 596 ELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQI 655 ++ L D ++ D E + + N+T A T A+ Sbjct: 1365 DILNNLKDFD-----RRVNDNKTAAEEALRKIPAINQTITEANEKTREAQQALGSAAAD- 1418 Query: 656 IYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAA 715 E++N ++A + + + ++ A+ R A + L +++ +KQLQ A Sbjct: 1419 ---ATEAKNKAHEAERIASAVQKNATSTKAEAER----TFAEVTDLDNEVNNMLKQLQEA 1471 Query: 716 ER------GDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNT 769 E+ DA Q + + + ++ A + ++A Sbjct: 1472 EKELKRKQDDADQDMMMAGMASQAAQEAEINARKA-----------------------KN 1508 Query: 770 AVNSARDAVRNLTEVVPQL----LDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKI 825 +V S + +L E + QL L++L +E + + + ++ + A K Sbjct: 1509 SVTSLLSIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAKKQ 1568 Query: 826 QVSMMFDGQSAVEV-HSRTSMDDLKAFTSLSLYMKPPVKRP 865 + ++M + E+ +++D++ + P +++P Sbjct: 1569 EAAIMDYNRDIEEIMKDIRNLEDIRKTLPSGCFNTPSIEKP 1609 Score = 82.8 bits (203), Expect = 3e-15 Identities = 73/266 (27%), Positives = 109/266 (40%), Gaps = 38/266 (14%) Query: 27 GDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAE------KCNAGFFHTLSGECV 80 G +A+ FD ++ Q+ ++ RV L RL + K +++ +S V Sbjct: 227 GRPSAYNFD----NSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAV 282 Query: 81 P--CDCNGNSNECLDGS--GYCVHCQRNTTGEHCEKCLDGYIGDSIRGA----PQFCQPC 132 C CNG+++EC+ +C+ NT G CEKCL + R A C PC Sbjct: 283 GGRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPC 342 Query: 133 PC-PLPHLANFAESCYRKNG-AVRCI-CNENYAGPNCERCAPGYY--GNPLLIGSTCKKC 187 C F YR G C C +N G +CERC ++ GN C C Sbjct: 343 DCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGN----NEACSSC 398 Query: 188 DCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG- 246 C S + CD G+C +C G KC+RC PG++ + C C+C Sbjct: 399 HC---SPVGSLSTQCDSY-GRC-SCKPGVMGDKCDRCQPGFH--SLTEAGCRPCSCDPSG 451 Query: 247 ---PCDSVTGECLEEGFEPPTGCDKC 269 C+ TG C+ + C++C Sbjct: 452 SIDECNIETGRCVCKDNVEGFNCERC 477 Score = 75.1 bits (183), Expect = 6e-13 Identities = 43/107 (40%), Positives = 52/107 (48%), Gaps = 11/107 (10%) Query: 155 CICNENYAGPNCERCAPGYYGNPLLIG--STCKKCDCSGNSDPNLIFEDCDEVTGQCRNC 212 C C Y G CE C GY +G S C C C+G+S E CD TG C NC Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHS------ETCDPETGVC-NC 742 Query: 213 LRNTTGFKCERCAPGYYGD--ARIAKNCAVCNCGGGPCDSVTGECLE 257 NT G CE+C+ GYYGD A + +C C C GG +V + E Sbjct: 743 RDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKE 789 Score = 37.0 bits (84), Expect = 0.18 Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 3/44 (6%) Query: 65 EKCNAGFFHTLSGE---CVPCDCNGNSNECLDGSGYCVHCQRNT 105 E+C GFF+ S C PC C G+S+ C + GY V+ +T Sbjct: 475 ERCKPGFFNLESSNPRGCTPCFCFGHSSVCTNAVGYSVYSISST 518 >gi|119703755 laminin, beta 2 precursor [Homo sapiens] Length = 1798 Score = 159 bits (401), Expect = 3e-38 Identities = 83/216 (38%), Positives = 115/216 (53%), Gaps = 22/216 (10%) Query: 79 CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP--L 136 C PC CNG+++EC +G C+ C+ +T GEHCE+C+ G+ GD C+PCPCP Sbjct: 874 CRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGP 933 Query: 137 PHLANFAESCYRK--NGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSD 194 +FA SC++ + + C C Y G CE CAPG++G+P G C+ C+CSGN D Sbjct: 934 GSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNID 993 Query: 195 PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC---GGGP---- 247 P + + CD TGQC CL +T G C C PG++G A ++C C C G P Sbjct: 994 P-MDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQA-ARQSCHRCTCNLLGTNPQQCP 1051 Query: 248 ------CDSVTGECLEEGFEPPTGCDKCV---WDLT 274 CD +G+C CD+C W+LT Sbjct: 1052 SPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLT 1087 Score = 113 bits (283), Expect = 1e-24 Identities = 187/837 (22%), Positives = 311/837 (37%), Gaps = 131/837 (15%) Query: 65 EKCNAGFFHTLS---GECVPCDCNGN-----SNECLDGSGYCVHCQRNTTGEHCEKCLDG 116 E C G F S G C C+C+GN + C +G C+ C +T G HC C G Sbjct: 966 EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPG 1025 Query: 117 YIGDSIRGAPQFCQPCPCPL----PHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172 + G + R Q C C C L P + C+ + +C C N GP+C+RCAP Sbjct: 1026 FHGQAAR---QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPN 1082 Query: 173 YYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA 232 ++ L G C+ C C + C+E TGQC +C G C C ++GD Sbjct: 1083 FWN--LTSGHGCQPCACHPSRARG---PTCNEFTGQC-HCRAGFGGRTCSECQELHWGDP 1136 Query: 233 RIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEG 287 + C C+C C TG C CD+C G Sbjct: 1137 GL--QCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCA---------------RG 1179 Query: 288 KSGVLSVSSGAAA-----HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSL 342 SG+ A R V ++ A L+ + E + L + ++ M+ Sbjct: 1180 FSGIFPACHPCHACFGDWDRVVQDLAARTQRLEQRAQELQQTGVLGAFE--SSFWHMQEK 1237 Query: 343 LSDVEELVEKEN-QASRKGQLVQ------KESMDTINHASQLVEQAHDMRDKIQEINNKM 395 L V+ +V N A+ QLV+ +E + H +QL D++D+ N+ + Sbjct: 1238 LGIVQGIVGARNTSAASTAQLVEATEELRREIGEATEHLTQLEADLTDVQDENFNANHAL 1297 Query: 396 LYYGEEH---ELSPKEISEKLVLAQ--KMLEEIRSRQPFFTQRELVDEEAD-EAYELLSQ 449 + L+ +++ + L L + L S + +Q + A+ A + S Sbjct: 1298 SGLERDRLALNLTLRQLDQHLDLLKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSP 1357 Query: 450 AESWQRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQ--ALNYVRDAEDMNRATAARQR 507 + + T L Q +D+N+K Q AL + A + D+N Sbjct: 1358 VSNSASARHRTEALMDA---QKEDFNSKHMANQRALGKLSAHTHTLSLTDINELVCGAPG 1414 Query: 508 DH------------EKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGI- 554 D + + R N + +T+ +L R T +EL + I Sbjct: 1415 DAPCATSPCGGAGCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRALAEGGSIL 1474 Query: 555 --YAEIDGAKSELQVKLS---NLSNLSHDLVQEAIDHAQDLQQEANELSRKLHSSDMNGL 609 AE SE Q + + +N S V++A Q+L Q + + +D + + Sbjct: 1475 SRVAETRRQASEAQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQ-EGADPDSI 1533 Query: 610 VQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQA 669 + A+ V E + +E + A+ R V I + + +E LL A Sbjct: 1534 ---EMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQDA 1590 Query: 670 RELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRL 729 R ++ AE +A + A+++ Q A+ G AQ + + Sbjct: 1591 RRARSWAEDEKQKA-------------------ETVQAALEEAQRAQ-GIAQGAIRGAVA 1630 Query: 730 ITEEANRTTMEVQQATAPMANNLTNWSQNLQHFD-------------SSAYNTAVNSARD 776 T + +T +VQ+ A L++ + + D S A +TA +A Sbjct: 1631 DTRDTEQTLYQVQERMAGAERALSSAGERARQLDALLEALKLKRAGNSLAASTAEETAGS 1690 Query: 777 AVRNLTEVVPQLL-----DQLRTVE--QKRPASNVSASIQRIRELIAQTRSVASKIQ 826 A + + QLL DQ +TV+ +R A V A+ R +L + R + Q Sbjct: 1691 A-QGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAAQ 1746 Score = 103 bits (258), Expect = 1e-21 Identities = 58/173 (33%), Positives = 81/173 (46%), Gaps = 25/173 (14%) Query: 80 VPCDCNGN---SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136 +PC CN S+EC G C+ C+ G C+ C GY G P CQ C C Sbjct: 781 LPCQCNPQGSLSSECNPHGGQCL-CKPGVVGRRCDLCAPGYYG----FGPTGCQACQC-- 833 Query: 137 PHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPN 196 H + C + +G +C+C G C+RC G +G P +C+ C C+G++D Sbjct: 834 SHEGALSSLCEKTSG--QCLCRTGAFGLRCDRCQRGQWGFP-----SCRPCVCNGHAD-- 884 Query: 197 LIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARI--AKNCAVCNCGGGP 247 +C+ TG C C +T G CERC G++GD R+ C C C GP Sbjct: 885 ----ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGP 933 Score = 97.4 bits (241), Expect = 1e-19 Identities = 60/205 (29%), Positives = 88/205 (42%), Gaps = 29/205 (14%) Query: 76 SGECVPCDCNGNSNEC--------LDGS---GYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124 S C C+C+G+++ C G+ G C CQ NT G HCE C + D + Sbjct: 341 SHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKD 400 Query: 125 A--PQFCQPCPCPLPHLANFAESCYRKNGAV------RCICNENYAGPNCERCAPGYYGN 176 P C+ C C P + C + +C C E+ G C++C G++G Sbjct: 401 LRDPAVCRSCDCD-PMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGL 459 Query: 177 PLLIGSTCKKCDCSGNSD-PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235 + C++C C+ P CD +G C C R TG C+RC PG++G + Sbjct: 460 SISDRLGCRRCQCNARGTVPG--STPCDPNSGSC-YCKRLVTGRGCDRCLPGHWGLSHDL 516 Query: 236 KNCAVCNCGGG-----PCDSVTGEC 255 C C+C G CD TG+C Sbjct: 517 LGCRPCDCDVGGALDPQCDEGTGQC 541 Score = 96.7 bits (239), Expect = 2e-19 Identities = 72/235 (30%), Positives = 102/235 (43%), Gaps = 40/235 (17%) Query: 82 CDCNGNSNECLDGSGYCVH----------CQRNTTGEHCEKCLDGYIGDSIR----GAPQ 127 C C G+++EC G H C+ NT G +CE+C D Y R G Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSH 342 Query: 128 FCQPCPCP-LPHLANFAESCYRKNGAVR---CI-CNENYAGPNCERCAPGYYGNP---LL 179 C+ C C H +F + Y +G V C C N AG +CE C P +Y +P L Sbjct: 343 ACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLR 402 Query: 180 IGSTCKKCDCS--GNSDPNLIFEDCDE----VTGQCRNCLRNTTGFKCERCAPGYYGDAR 233 + C+ CDC G+ D D V+GQCR C + G +C++C G++G + Sbjct: 403 DPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCR-CKEHVVGTRCQQCRDGFFGLSI 461 Query: 234 IAK-NCAVCNC-------GGGPCDSVTGECLEEGFEPPTGCDKCV---WDLTDAL 277 + C C C G PCD +G C + GCD+C+ W L+ L Sbjct: 462 SDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDL 516 Score = 83.6 bits (205), Expect = 2e-15 Identities = 55/168 (32%), Positives = 79/168 (47%), Gaps = 31/168 (18%) Query: 79 CVPCDCNGNSNECLDG--------------SGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124 C CDC+ ++ DG SG C C+ + G C++C DG+ G SI Sbjct: 407 CRSCDCDPMGSQ--DGGRCDSHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFGLSISD 463 Query: 125 APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG-NPLLIGST 183 C+ C C + C +G+ C C G C+RC PG++G + L+G Sbjct: 464 RLG-CRRCQCNARGTVPGSTPCDPNSGS--CYCKRLVTGRGCDRCLPGHWGLSHDLLG-- 518 Query: 184 CKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229 C+ CDC G DP CDE TGQC +C ++ G +CE+ PGY+ Sbjct: 519 CRPCDCDVGGALDPQ-----CDEGTGQC-HCRQHMVGRRCEQVQPGYF 560 Score = 74.3 bits (181), Expect = 1e-12 Identities = 46/144 (31%), Positives = 66/144 (45%), Gaps = 22/144 (15%) Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGST-CKKCDCSG 191 PC + + C G +C+C G C+ CAPGYYG G T C+ C CS Sbjct: 782 PCQCNPQGSLSSECNPHGG--QCLCKPGVVGRRCDLCAPGYYG----FGPTGCQACQCSH 835 Query: 192 NSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG--GPCD 249 + + C++ +GQC C G +C+RC G +G +C C C G C+ Sbjct: 836 EGALSSL---CEKTSGQCL-CRTGAFGLRCDRCQRGQWG----FPSCRPCVCNGHADECN 887 Query: 250 SVTGECLEEGFEPPTG---CDKCV 270 + TG CL G TG C++C+ Sbjct: 888 THTGACL--GCRDHTGGEHCERCI 909 Score = 58.9 bits (141), Expect = 4e-08 Identities = 38/120 (31%), Positives = 55/120 (45%), Gaps = 19/120 (15%) Query: 65 EKCNAGFFHTLSGE---CVPCDCNGN-----SNECLDGSGYCVHCQRNTTGEHCEKCLDG 116 ++C GFF + C C CN S C SG C +C+R TG C++CL G Sbjct: 450 QQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSC-YCKRLVTGRGCDRCLPG 508 Query: 117 YIGDS--IRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174 + G S + G C+PC C + + C G +C C ++ G CE+ PGY+ Sbjct: 509 HWGLSHDLLG----CRPCDCDVGGALD--PQC--DEGTGQCHCRQHMVGRRCEQVQPGYF 560 Score = 56.2 bits (134), Expect = 3e-07 Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 18/138 (13%) Query: 62 PAAEKCNAGFFHTLSGE-CVPCDCN---GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117 P+ ++C F++ SG C PC C+ C + +G C HC+ G C +C + + Sbjct: 1074 PSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQC-HCRAGFGGRTCSECQELH 1132 Query: 118 IGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNP 177 GD C C C + C+R G C C +G C++CA G+ G Sbjct: 1133 WGDP----GLQCHACDCDSRGIDT--PQCHRFTG--HCSCRPGVSGVRCDQCARGFSG-- 1182 Query: 178 LLIGSTCKKCD-CSGNSD 194 I C C C G+ D Sbjct: 1183 --IFPACHPCHACFGDWD 1198 Score = 39.3 bits (90), Expect = 0.035 Identities = 68/328 (20%), Positives = 134/328 (40%), Gaps = 47/328 (14%) Query: 341 SLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAH-DMRDKIQEINNKMLYYG 399 S+LS V E + ++A ++ Q ++D N + VEQA+ ++++ IQ + + + G Sbjct: 1472 SILSRVAETRRQASEAQQRAQA----ALDKANASRGQVEQANQELQELIQSVKDFLNQEG 1527 Query: 400 EEH-----------ELSPKEISEKLV-LAQKMLEEIRSRQPF--FTQRELVD-EEADEAY 444 + ELS +E++ LA + E +RS R + D A++ Sbjct: 1528 ADPDSIEMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLL 1587 Query: 445 ELLSQAESWQRLHNETRTLFPVVLEQLDDYN-----------AKLSDLQEALDQALNYVR 493 + +A SW + LE+ A D ++ L Q + Sbjct: 1588 QDARRARSWAEDEKQKAETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMA 1647 Query: 494 DAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASG 553 AE + R R + E ++ + +++ ST+ ++ + + E + +++ G Sbjct: 1648 GAERALSSAGERARQLDALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLG 1707 Query: 554 IYAEIDGAKSE--------LQVKLSNLSNLSHDLVQEAIDHAQDLQQ-----EANELSRK 600 + A +E Q + L + + DL+Q A D Q LQ+ E NE + + Sbjct: 1708 DQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALE 1767 Query: 601 LHSSDMNGL---VQKALDASNVYENIVN 625 ++ ++GL ++ L A N+ I N Sbjct: 1768 SKAAQLDGLEARMRSVLQAINLQVQIYN 1795 >gi|110611156 laminin, gamma 3 precursor [Homo sapiens] Length = 1575 Score = 145 bits (367), Expect = 3e-34 Identities = 84/224 (37%), Positives = 107/224 (47%), Gaps = 26/224 (11%) Query: 65 EKCNAGFFHTLS-----GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119 E C G+ + CVPC CN + C +G CV C +T G CE+CL G+ G Sbjct: 685 ESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDPNTGICV-CSHHTEGPSCERCLPGFYG 742 Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPL 178 + G CQPCPCP A + ++ V C C G CE C G++G+PL Sbjct: 743 NPFAGQADDCQPCPCP----GQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPL 798 Query: 179 -LIG--STCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA--- 232 L G C +C CSGN DPN + +CD ++G C CL NTTG CE C G+YG A Sbjct: 799 GLFGHPQPCHQCQCSGNVDPNAV-GNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAP 857 Query: 233 RIAKNCAVCNCGGG-------PCDSVTGECLEEGFEPPTGCDKC 269 R A C C+C PCD VTG+C C +C Sbjct: 858 RPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRC 901 Score = 119 bits (297), Expect = 4e-26 Identities = 193/862 (22%), Positives = 320/862 (37%), Gaps = 119/862 (13%) Query: 29 DNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPA-----AEKCNAGFFHTLSG------ 77 D+ P G SA PE+ E V PP E C+ GFF G Sbjct: 750 DDCQPCPCPGQSAC--TTIPESRE--VVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQ 805 Query: 78 ECVPCDCNGNSN-----ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP-QFCQP 131 C C C+GN + C SG+C+ C NTTG+HCE C +G+ G ++ P C P Sbjct: 806 PCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMP 865 Query: 132 CPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCS- 190 C C + C G +C C + +C RC PG++ L G C+ C C Sbjct: 866 CSCHPQGSVSEQMPCDPVTG--QCSCLPHVTARDCSRCYPGFF--DLQPGRGCRSCKCHP 921 Query: 191 -GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCD 249 G+ + + C TGQC C TG C+RC G++G + K C C C P Sbjct: 922 LGSQE-----DQCHPKTGQC-TCRPGVTGQACDRCQLGFFGFS--IKGCRACRC--SPLG 971 Query: 250 SVTGECLEE-------GFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHR 302 + + +C E GFE CD+C D L A +G S A Sbjct: 972 AASAQCHENGTCVCRPGFE-GYKCDRC----HDNFFLTA----DGTHCQQCPSCYALVKE 1022 Query: 303 HVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKGQL 362 ++ A + L + L + + I E + L +R+ L Sbjct: 1023 EAAKLKARLTLTEGWLQGSDCGSPWGPLDILLGEAPRGDVYQGHHLL-----PGAREAFL 1077 Query: 363 VQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEE 422 Q S++ A+ R+++Q +N + + ++++ + + EE Sbjct: 1078 EQMMSLEGAVKAA---------REQLQRLNKGARCAQAGSQKTCTQLADLEAVLESSEEE 1128 Query: 423 IRSRQPFFTQRELVDEEADEAYE---LLSQAESWQRLHNETRT-LFPVVLEQLDDYNAKL 478 I E+ E + + L ++A + R H +T T + L N Sbjct: 1129 ILHAAAILASLEIPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRALLASNTSY 1188 Query: 479 SDLQEALD--QALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTT 536 + L L+ AL RD ED + A Q+ V + E V ++ + T Sbjct: 1189 ALLWNLLEGRVALETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESV-LATVQQVGADTA 1247 Query: 537 PRLTLSELDDIIKNASGIYAEIDGAKSE-LQVKLSNLSNLSHDLVQEAIDHAQDLQQEAN 595 P L L + S AE G K++ L+ +++ +++ + + AQ ++ Sbjct: 1248 PYLALLASPGALPQKS--RAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQATLRQTE 1305 Query: 596 ELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQI 655 L+ KLH L Q S + + A + + + G+ Q Sbjct: 1306 PLT-KLHQEARAALTQ---------------ASSSVQAATVTVMGARTLLADLEGMKLQF 1349 Query: 656 IYHKDESENLLNQARELQAKAESSSDEAVADT-------SRRVGGALARKSALKTR---- 704 KD++ LQ KA+S SD +ADT R +G A S+ K + Sbjct: 1350 PRPKDQA--------ALQRKADSVSDRLLADTRKKTKQAERMLGNAAPLSSSAKKKGREA 1401 Query: 705 ---LSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQH 761 D+ K +A R Q SRL ++ QQ A A Sbjct: 1402 EVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQASQQVLASEARRQELEEAERVG 1461 Query: 762 FDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVE-QKRPASNVSA---SIQRIRELIAQ 817 S + +R ++ E + +LL +L +++ + PA ++ +++R+R + Sbjct: 1462 AGLSEMEQQIRESRISLEKDIETLSELLARLGSLDTHQAPAQALNETQWALERLRLQLGS 1521 Query: 818 TRSVASKIQVSMMFDGQSAVEV 839 S+ K+ + Q +++ Sbjct: 1522 PGSLQRKLSLLEQESQQQELQI 1543 Score = 97.4 bits (241), Expect = 1e-19 Identities = 68/201 (33%), Positives = 91/201 (45%), Gaps = 22/201 (10%) Query: 82 CDCNGNSNEC---LDGSGYCVHCQRNTTGEHCEKCL----DGYIGDSIRGAPQFCQPCPC 134 C CNG+++EC + G C CQ NTTG CE+CL D A C PC C Sbjct: 271 CKCNGHASECGPDVAGQLAC-RCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC 329 Query: 135 P-LPHLANFAESCYRKNG-AVRC-ICNENYAGPNCERCAPGYY-GNPLLIGSTCKKCDCS 190 F +R G RC C ++ AGP+CERC +Y +P + C+ CDC Sbjct: 330 SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRM---PCQPCDCQ 386 Query: 191 GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG--PC 248 +L CD+ TG C C TG+KC+RC PG++ + CN G C Sbjct: 387 SAGSLHL---QCDD-TGTCA-CKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTC 441 Query: 249 DSVTGECLEEGFEPPTGCDKC 269 D +G C + CD+C Sbjct: 442 DPRSGRCPCKENVEGNLCDRC 462 Score = 93.2 bits (230), Expect = 2e-18 Identities = 55/178 (30%), Positives = 76/178 (42%), Gaps = 26/178 (14%) Query: 78 ECVPCDCNGNSNECL---------DGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF 128 EC+PC+C+G S EC G C HC+ +T G HCE+C + + R Sbjct: 323 ECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPR---MP 379 Query: 129 CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCD 188 CQPC C + C + C C G C+RC PG++ L C+ C Sbjct: 380 CQPCDC--QSAGSLHLQC---DDTGTCACKPTVTGWKCDRCLPGFHS---LSEGGCRPCT 431 Query: 189 CSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCGG 245 C +P + CD +G+C C N G C+RC PG + C+ C C G Sbjct: 432 C----NPAGSLDTCDPRSGRC-PCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYG 484 Score = 66.2 bits (160), Expect = 3e-10 Identities = 42/134 (31%), Positives = 58/134 (43%), Gaps = 17/134 (12%) Query: 151 GAVRCICNENYAGPNCERCAPGYYGNPLLIGST-----CKKCDCSGNSDPNLIFEDCDEV 205 G + C C N G +CERC P + P G+ C C+CSG S+ + Sbjct: 286 GQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRS 345 Query: 206 T---GQCRNCLRNTTGFKCERCAPGYY-GDARIAKNCAVCNCGGG-----PCDSVTGECL 256 T G+C +C +T G CERC +Y D R+ C C+C CD TG C Sbjct: 346 TGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--CQPCDCQSAGSLHLQCDD-TGTCA 402 Query: 257 EEGFEPPTGCDKCV 270 + CD+C+ Sbjct: 403 CKPTVTGWKCDRCL 416 Score = 64.3 bits (155), Expect = 1e-09 Identities = 38/98 (38%), Positives = 46/98 (46%), Gaps = 18/98 (18%) Query: 155 CICNENYAGPNCERCAPGY-----YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQC 209 C C Y G CE CAPGY G P ++C C C+ + CD TG C Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPY---ASCVPCTCNQHG-------TCDPNTGIC 722 Query: 210 RNCLRNTTGFKCERCAPGYYGD--ARIAKNCAVCNCGG 245 C +T G CERC PG+YG+ A A +C C C G Sbjct: 723 -VCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPG 759 Score = 43.1 bits (100), Expect = 0.002 Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 4/72 (5%) Query: 65 EKCNAGFFHTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 122 ++C GF G C PC CN G+ + C SG C C+ N G C++C G Sbjct: 413 DRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGRC-PCKENVEGNLCDRCRPGTFNLQP 471 Query: 123 RGAPQFCQPCPC 134 P C C C Sbjct: 472 HN-PAGCSSCFC 482 >gi|157419130 laminin, alpha 4 isoform 3 precursor [Homo sapiens] Length = 120 Score = 135 bits (341), Expect = 3e-31 Identities = 65/65 (100%), Positives = 65/65 (100%) Query: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL Sbjct: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60 Query: 61 PPAAE 65 PPAAE Sbjct: 61 PPAAE 65 >gi|157419128 laminin, alpha 4 isoform 3 precursor [Homo sapiens] Length = 120 Score = 135 bits (341), Expect = 3e-31 Identities = 65/65 (100%), Positives = 65/65 (100%) Query: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL Sbjct: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60 Query: 61 PPAAE 65 PPAAE Sbjct: 61 PPAAE 65 >gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] Length = 639 Score = 132 bits (331), Expect = 4e-30 Identities = 66/185 (35%), Positives = 92/185 (49%), Gaps = 14/185 (7%) Query: 57 LGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDG 116 +G + ++C G++ C+PC CN S C +G C++CQ N+ G HCE+C +G Sbjct: 313 VGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEG 372 Query: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNE---NYAGPNCERCAPGY 173 + A + C CPC SC K+ + C++ Y GPNC +C GY Sbjct: 373 FYQSP--DATKECLRCPCSA---VTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGY 427 Query: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR 233 Y S C+KC C G+ DP + C +G+C NCL NTTGF CE C GY D Sbjct: 428 YN----FDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHD-- 481 Query: 234 IAKNC 238 + NC Sbjct: 482 LEGNC 486 Score = 105 bits (262), Expect = 4e-22 Identities = 66/194 (34%), Positives = 85/194 (43%), Gaps = 29/194 (14%) Query: 82 CDCNG----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137 C+C+ N N C +G C C+ G HCE C +G+ + G CQPC C P Sbjct: 241 CNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSG---LCQPCDCS-P 295 Query: 138 HLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNL 197 H A + C N + +C C G C+RC GYYG + C C C+ S Sbjct: 296 HGA-LSIPC---NSSGKCQCKVGVIGSICDRCQDGYYG---FSKNGCLPCQCNNRS---- 344 Query: 198 IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSV--TGEC 255 CD +TG C NC N+ G CE C G+Y K C C PC +V TG C Sbjct: 345 --ASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRC-----PCSAVTSTGSC 397 Query: 256 LEEGFEPPTGCDKC 269 + E CD+C Sbjct: 398 SIKSSELEPECDQC 411 >gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] Length = 1193 Score = 131 bits (329), Expect = 7e-30 Identities = 174/804 (21%), Positives = 315/804 (39%), Gaps = 138/804 (17%) Query: 77 GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136 G C+PC+C G C +G C N E C C G+ D P+ C+PCPC Sbjct: 411 GTCIPCNCQGGG-ACDPDTGDCYSGDENPDIE-CADCPIGFYNDP--HDPRSCKPCPCH- 465 Query: 137 PHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLIGST---CKKCDCSGN 192 F+ S + V C C G CE CA GY+G+P C+ C C+ N Sbjct: 466 ---NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN 522 Query: 193 SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGD---ARIAKNCAVCNC---GGG 246 DP+ +CD +TG+C C+ NT G C++C GY+GD A C CNC G Sbjct: 523 VDPSAS-GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581 Query: 247 P--CDSVTGECL-EEGFEPPT------GCDKCVWD--------LTDALRLAAL-SIEEGK 288 P C S G C+ + GF P C C + R+ AL S +G Sbjct: 582 PVGCRS-DGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGG 640 Query: 289 SGVLSVSSGAAAHRHVNEINATIYLLKTKLSE-RENQYALRKIQINNAENTMKSLLSDVE 347 GV+ + + + I L ++SE L+ ++ + EN+ +S L D++ Sbjct: 641 DGVVPDTELEGRMQQAEQALQDI-LRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLK 699 Query: 348 ELVEK---------------------------ENQAS----------------------R 358 VE+ E++AS + Sbjct: 700 MTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQ 759 Query: 359 KGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQK 418 + + + +++ ++ QL + D + + K L+ G + + L +K Sbjct: 760 EATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEK 819 Query: 419 MLEEIRSRQPFFTQRELVDEEADEAYE-LLSQAESWQRLHNETRTLFPVVLEQLDDYNAK 477 + + Q + + EAD +Y+ L +S RL + F V E+ K Sbjct: 820 LEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQV--EEAKRIKQK 877 Query: 478 LSDLQEALDQALN-YVRDAEDM-NRATAARQ--RDHEKQQERVREQMEVVNMSLSTSADS 533 L + + ++ + R +++ N A+Q ++ + +E+ + + N++ S + ++ Sbjct: 878 ADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEA 937 Query: 534 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 593 L+ T E++ I+KN ++D K+E + + LS +S V +A D Q ++ Sbjct: 938 LSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQK-VSDASDKTQQAERA 996 Query: 594 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGI-- 651 + + NG + +S + + I + EAN TA+ AL + S + Sbjct: 997 LGSAAADAQRA-KNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMRE 1055 Query: 652 --------DTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGAL-------- 695 + + + D + ++ +A+++ +A+++ + DT + G L Sbjct: 1056 VEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNAG-VTIQDTLNTLDGLLHLMDQPLS 1114 Query: 696 ----------ARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQAT 745 + S KT+++ ++ + + A+Q+ G L+ + +V+ Sbjct: 1115 VDEEGLVLLEQKLSRAKTQINSQLRPMMSELEERARQQRGHLHLLETSIDGILADVK--- 1171 Query: 746 APMANNLTNWSQNLQHFDSSAYNT 769 NL N NL YNT Sbjct: 1172 -----NLENIRDNL---PPGCYNT 1187 Score = 95.9 bits (237), Expect = 3e-19 Identities = 62/182 (34%), Positives = 82/182 (45%), Gaps = 36/182 (19%) Query: 82 CDCNGNSNECL--------DGSGY-CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPC 132 CDCNG S +C+ G+G+ C++C NT G HCEKC +G+ R C PC Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR---CLPC 84 Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC-------- 184 C + R + + RC C G C+RC PG++ +L + C Sbjct: 85 NC-----NSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH---MLTDAGCTQDQRLLD 136 Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNC 243 KCDC DP I CD G+C C TG +C+RC GYY D + C C C Sbjct: 137 SKCDC----DPAGIAGPCD--AGRC-VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189 Query: 244 GG 245 G Sbjct: 190 YG 191 Score = 73.9 bits (180), Expect = 1e-12 Identities = 49/140 (35%), Positives = 63/140 (45%), Gaps = 23/140 (16%) Query: 65 EKCNAGFF-HTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121 EKC GF+ H C+PC+CN G+ + D SG C C+ TG C++CL G+ + Sbjct: 66 EKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRC-SCKPGVTGARCDRCLPGFHMLT 124 Query: 122 IRGAPQ----FCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY--- 174 G Q C C A A C A RC+C G C+RC GYY Sbjct: 125 DAGCTQDQRLLDSKCDC---DPAGIAGPC----DAGRCVCKPAVTGERCDRCRSGYYNLD 177 Query: 175 -GNPLLIGSTCKKCDCSGNS 193 GNP C +C C G+S Sbjct: 178 GGNP----EGCTQCFCYGHS 193 Score = 71.2 bits (173), Expect = 8e-12 Identities = 147/690 (21%), Positives = 246/690 (35%), Gaps = 147/690 (21%) Query: 154 RCICNENYAGPNCERCAPGYYGNPLLIG--STCKKCDC--------------SGNSDPNL 197 +CIC Y G C+ CA GY + +G TC C+C SG+ +P++ Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440 Query: 198 IFEDC-------------------------------DEVTGQCRNCLRNTTGFKCERCAP 226 DC +EV C NC TG +CE CA Sbjct: 441 ECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV--CNNCPPGVTGARCELCAD 498 Query: 227 GYYGDA----RIAKNCAVCNC-------GGGPCDSVTGECL--------------EEGF- 260 GY+GD + C C C G CD +TG CL + G+ Sbjct: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558 Query: 261 -EP--PTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTK 317 +P P DKC + + + + V G H Y Sbjct: 559 GDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAFSCPACY----- 613 Query: 318 LSERENQYALRKIQINNAENTMKSLLSDVE--ELVEKENQASRKGQLVQKESMDTINHAS 375 NQ ++ Q M++L+S + + V + + + Q ++ D + A Sbjct: 614 -----NQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQ 668 Query: 376 QLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQREL 435 + + ++ ++ ++ Y + + L + +R TQ + Sbjct: 669 ISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQ- 727 Query: 436 VDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDY---NAKLSDLQEALDQALNYV 492 LS AES L N + D Y N S QEA A ++V Sbjct: 728 -----------LSLAESEASLGNTN-------IPASDHYVGPNGFKSLAQEATRLAESHV 769 Query: 493 RDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRL------TLSELDD 546 A +M + T + ++ VR+ + S S S D L T S Sbjct: 770 ESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQ 829 Query: 547 IIKNASGIYAEIDGAKS-----ELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRKL 601 + + A+ AEI+ +S L +S L +S Q ++ A+ ++Q+A+ LS + Sbjct: 830 LTREAT--QAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQ--VEEAKRIKQKADSLSSLV 885 Query: 602 -HSSDMNGLVQKAL-----DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQI 655 D QK L +A + +N + ++++ A R +A+S + Sbjct: 886 TRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALS-MGNAT 944 Query: 656 IYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAA 715 Y E E++L RE + ++ EA A+ R S + ++SDA + Q A Sbjct: 945 FY---EVESILKNLREFDLQVDNRKAEAEE--------AMKRLSYISQKVSDASDKTQQA 993 Query: 716 ER--GDAQQRLGQSRLITEEANRTTMEVQQ 743 ER G A +++ EA + E++Q Sbjct: 994 ERALGSAAADAQRAKNGAGEALEISSEIEQ 1023 Score = 31.2 bits (69), Expect = 9.6 Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 7/65 (10%) Query: 65 EKCNAGFFHTLSGE---CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121 ++C +G+++ G C C C G+S C + Y VH +T + +DG+ Sbjct: 167 DRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQD----VDGWKAVQ 222 Query: 122 IRGAP 126 G+P Sbjct: 223 RNGSP 227 >gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] Length = 1111 Score = 129 bits (325), Expect = 2e-29 Identities = 150/645 (23%), Positives = 259/645 (40%), Gaps = 98/645 (15%) Query: 77 GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136 G C+PC+C G C +G C N E C C G+ D P+ C+PCPC Sbjct: 411 GTCIPCNCQGGG-ACDPDTGDCYSGDENPDIE-CADCPIGFYNDP--HDPRSCKPCPCH- 465 Query: 137 PHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLIGST---CKKCDCSGN 192 F+ S + V C C G CE CA GY+G+P C+ C C+ N Sbjct: 466 ---NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN 522 Query: 193 SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGD---ARIAKNCAVCNC---GGG 246 DP+ +CD +TG+C C+ NT G C++C GY+GD A C CNC G Sbjct: 523 VDPSAS-GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581 Query: 247 P--CDSVTGECL-EEGFEPPT------GCDKCVWD--------LTDALRLAAL-SIEEGK 288 P C S G C+ + GF P C C + R+ AL S +G Sbjct: 582 PVGCRS-DGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGG 640 Query: 289 SGVLSVSSGAAAHRHVNEINATIYLLKTKLSE-RENQYALRKIQINNAENTMKSLLSDVE 347 GV+ + + + I L ++SE L+ ++ + EN+ +S L D++ Sbjct: 641 DGVVPDTELEGRMQQAEQALQDI-LRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLK 699 Query: 348 ELVEK---------------------------ENQAS----------------------R 358 VE+ E++AS + Sbjct: 700 MTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQ 759 Query: 359 KGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQK 418 + + + +++ ++ QL + D + + K L+ G + + L +K Sbjct: 760 EATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEK 819 Query: 419 MLEEIRSRQPFFTQRELVDEEADEAYE-LLSQAESWQRLHNETRTLFPVVLEQLDDYNAK 477 + + Q + + EAD +Y+ L +S RL + F V E+ K Sbjct: 820 LEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQV--EEAKRIKQK 877 Query: 478 LSDLQEALDQALN-YVRDAEDM-NRATAARQ--RDHEKQQERVREQMEVVNMSLSTSADS 533 L + + ++ + R +++ N A+Q ++ + +E+ + + N++ S + ++ Sbjct: 878 ADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEA 937 Query: 534 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 593 L+ T E++ I+KN ++D K+E + + LS +S V +A D Q ++ Sbjct: 938 LSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQK-VSDASDKTQQAERA 996 Query: 594 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFAL 638 + + NG + +S + + I + EAN TA+ AL Sbjct: 997 LGSAAADAQRA-KNGAGEALEISSEIEQEIGSLNLEANVTADGAL 1040 Score = 95.9 bits (237), Expect = 3e-19 Identities = 62/182 (34%), Positives = 82/182 (45%), Gaps = 36/182 (19%) Query: 82 CDCNGNSNECL--------DGSGY-CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPC 132 CDCNG S +C+ G+G+ C++C NT G HCEKC +G+ R C PC Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR---CLPC 84 Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC-------- 184 C + R + + RC C G C+RC PG++ +L + C Sbjct: 85 NC-----NSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH---MLTDAGCTQDQRLLD 136 Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNC 243 KCDC DP I CD G+C C TG +C+RC GYY D + C C C Sbjct: 137 SKCDC----DPAGIAGPCD--AGRC-VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189 Query: 244 GG 245 G Sbjct: 190 YG 191 Score = 73.9 bits (180), Expect = 1e-12 Identities = 49/140 (35%), Positives = 63/140 (45%), Gaps = 23/140 (16%) Query: 65 EKCNAGFF-HTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121 EKC GF+ H C+PC+CN G+ + D SG C C+ TG C++CL G+ + Sbjct: 66 EKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRC-SCKPGVTGARCDRCLPGFHMLT 124 Query: 122 IRGAPQ----FCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY--- 174 G Q C C A A C A RC+C G C+RC GYY Sbjct: 125 DAGCTQDQRLLDSKCDC---DPAGIAGPC----DAGRCVCKPAVTGERCDRCRSGYYNLD 177 Query: 175 -GNPLLIGSTCKKCDCSGNS 193 GNP C +C C G+S Sbjct: 178 GGNP----EGCTQCFCYGHS 193 Score = 71.2 bits (173), Expect = 8e-12 Identities = 147/690 (21%), Positives = 246/690 (35%), Gaps = 147/690 (21%) Query: 154 RCICNENYAGPNCERCAPGYYGNPLLIG--STCKKCDC--------------SGNSDPNL 197 +CIC Y G C+ CA GY + +G TC C+C SG+ +P++ Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440 Query: 198 IFEDC-------------------------------DEVTGQCRNCLRNTTGFKCERCAP 226 DC +EV C NC TG +CE CA Sbjct: 441 ECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV--CNNCPPGVTGARCELCAD 498 Query: 227 GYYGDA----RIAKNCAVCNC-------GGGPCDSVTGECL--------------EEGF- 260 GY+GD + C C C G CD +TG CL + G+ Sbjct: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558 Query: 261 -EP--PTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTK 317 +P P DKC + + + + V G H Y Sbjct: 559 GDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAFSCPACY----- 613 Query: 318 LSERENQYALRKIQINNAENTMKSLLSDVE--ELVEKENQASRKGQLVQKESMDTINHAS 375 NQ ++ Q M++L+S + + V + + + Q ++ D + A Sbjct: 614 -----NQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQ 668 Query: 376 QLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQREL 435 + + ++ ++ ++ Y + + L + +R TQ + Sbjct: 669 ISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQ- 727 Query: 436 VDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDY---NAKLSDLQEALDQALNYV 492 LS AES L N + D Y N S QEA A ++V Sbjct: 728 -----------LSLAESEASLGNTN-------IPASDHYVGPNGFKSLAQEATRLAESHV 769 Query: 493 RDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRL------TLSELDD 546 A +M + T + ++ VR+ + S S S D L T S Sbjct: 770 ESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQ 829 Query: 547 IIKNASGIYAEIDGAKS-----ELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRKL 601 + + A+ AEI+ +S L +S L +S Q ++ A+ ++Q+A+ LS + Sbjct: 830 LTREAT--QAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQ--VEEAKRIKQKADSLSSLV 885 Query: 602 -HSSDMNGLVQKAL-----DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQI 655 D QK L +A + +N + ++++ A R +A+S + Sbjct: 886 TRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALS-MGNAT 944 Query: 656 IYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAA 715 Y E E++L RE + ++ EA A+ R S + ++SDA + Q A Sbjct: 945 FY---EVESILKNLREFDLQVDNRKAEAEE--------AMKRLSYISQKVSDASDKTQQA 993 Query: 716 ER--GDAQQRLGQSRLITEEANRTTMEVQQ 743 ER G A +++ EA + E++Q Sbjct: 994 ERALGSAAADAQRAKNGAGEALEISSEIEQ 1023 Score = 31.2 bits (69), Expect = 9.6 Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 7/65 (10%) Query: 65 EKCNAGFFHTLSGE---CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121 ++C +G+++ G C C C G+S C + Y VH +T + +DG+ Sbjct: 167 DRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQD----VDGWKAVQ 222 Query: 122 IRGAP 126 G+P Sbjct: 223 RNGSP 227 >gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] Length = 4391 Score = 128 bits (321), Expect = 6e-29 Identities = 82/264 (31%), Positives = 117/264 (44%), Gaps = 30/264 (11%) Query: 15 LLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHT 74 L+ ++ + A + D+ G+ E + G P+ + C+ G+ T Sbjct: 1088 LIRASYAQQPAESRVSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRT 1147 Query: 75 LSG----ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQ 130 SG C C C+G+S C +G C CQ +T G CE+C GY GD+ RG PQ CQ Sbjct: 1148 PSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQ 1207 Query: 131 PCPC-PLPHLANFAESCY-RKNGAVRC-ICNENYAGPNCERCAPGYYGNPLLIGSTCKK- 186 CPC P A +C+ +G C C+ ++G +CERCAPGYYGNP G C++ Sbjct: 1208 LCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQ-GQPCQRD 1266 Query: 187 --------CDCSGNSDP-NLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAK 236 C+C DP + CD GQC+ C G C C P ++ A Sbjct: 1267 SQVPGPIGCNC----DPQGSVSSQCD-AAGQCQ-CKAQVEGLTCSHCRPHHFHLSASNPD 1320 Query: 237 NCAVCNCGGGPCDSVTGECLEEGF 260 C C C G +T +C + Sbjct: 1321 GCLPCFCMG-----ITQQCASSAY 1339 Score = 125 bits (314), Expect = 4e-28 Identities = 74/230 (32%), Positives = 105/230 (45%), Gaps = 23/230 (10%) Query: 29 DNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSGE----CVPCDC 84 D A + +++ GR E E R +G + E C+A F G C C+C Sbjct: 709 DIAMDTTVTHATSHGRAHSVE--ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNC 766 Query: 85 NGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP-LPHLANFA 143 NG+++ C G+C++CQ NT G C KC G+ GD+++ C+PCPCP + F+ Sbjct: 767 NGHASSCDPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFS 826 Query: 144 ESCY-RKNGAVRC-ICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFED 201 ++C+ +G C C Y G CE CAPGY GNP+ G C+ N Sbjct: 827 DTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPV--------NQEIVR 878 Query: 202 CDE-----VTGQCRNCLRNTTGFKCERCAPG-YYGDARIAKNCAVCNCGG 245 CDE +G+ C N G C CA G ++ R C C C G Sbjct: 879 CDERGSMGTSGEACRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCMG 928 Score = 117 bits (292), Expect = 1e-25 Identities = 59/143 (41%), Positives = 74/143 (51%), Gaps = 7/143 (4%) Query: 49 ETSEPRVALGRLPPAAEKCNAGFFHTLSG----ECVPCDCNGNSNECLDGSGYCVHCQRN 104 E E R G + + + C G+ T SG C C+CNG+S+ C +G C CQ N Sbjct: 1526 EVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHN 1585 Query: 105 TTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLAN-FAESCYRKN-GAVRC-ICNENY 161 GE CE C GY GD+ G P+ CQPC CPL + N F+ +C G RC C Y Sbjct: 1586 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGY 1645 Query: 162 AGPNCERCAPGYYGNPLLIGSTC 184 G CE+C PGY GNP + G C Sbjct: 1646 TGQYCEQCGPGYVGNPSVQGGQC 1668 Score = 78.2 bits (191), Expect = 7e-14 Identities = 40/93 (43%), Positives = 50/93 (53%), Gaps = 11/93 (11%) Query: 155 CICNENYAGPNCERCAPGYY--GNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNC 212 C C Y G +C+ CAPGY G+ L +G C+ C+C+G+SD C TG C C Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGH-CELCECNGHSDL------CHPETGACSQC 1582 Query: 213 LRNTTGFKCERCAPGYYGDARIA--KNCAVCNC 243 N G CE CAPGYYGDA ++C C C Sbjct: 1583 QHNAAGEFCELCAPGYYGDATAGTPEDCQPCAC 1615 Score = 70.1 bits (170), Expect = 2e-11 Identities = 41/138 (29%), Positives = 57/138 (41%), Gaps = 10/138 (7%) Query: 101 CQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNEN 160 C G C+ C GY C+ C C ++ C+ + GA C N Sbjct: 1532 CPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN-----GHSDLCHPETGACSQ-CQHN 1585 Query: 161 YAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDCDEVTG---QCRNCLRNT 216 AG CE CAPGYYG+ C+ C C + N+ C+ + +C C Sbjct: 1586 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGY 1645 Query: 217 TGFKCERCAPGYYGDARI 234 TG CE+C PGY G+ + Sbjct: 1646 TGQYCEQCGPGYVGNPSV 1663 Score = 66.2 bits (160), Expect = 3e-10 Identities = 36/135 (26%), Positives = 68/135 (50%), Gaps = 7/135 (5%) Query: 1490 IRLRTRSSHGMIFYVSDQ-----EENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDG 1544 + +RT ++ G++ + + + DF++L L G LV+ + +G + ++ S++ NDG Sbjct: 4232 LEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEARLVSEDPINDG 4291 Query: 1545 LWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSI 1604 WH V +RE G + +DG ++ P KG +Y+GG + + +S Sbjct: 4292 EWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSS- 4350 Query: 1605 YSFSGCLSNLQLNGA 1619 +GC+ NL L+ A Sbjct: 4351 -GITGCVKNLVLHSA 4364 Score = 54.3 bits (129), Expect = 1e-06 Identities = 39/149 (26%), Positives = 60/149 (40%), Gaps = 10/149 (6%) Query: 1511 DFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEE 1570 DF++L + G L + + +G +RS E G WH V R G L ++G R + Sbjct: 3978 DFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGRWHRVSAERLNKDGSLRVNGGRPVLR 4037 Query: 1571 SLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASI--------- 1621 S P + +YLGGV P + + N F GC+ + +NG + Sbjct: 4038 SSPGKSQGLNLHTLLYLGGVEPSVPL-SPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGS 4096 Query: 1622 TSASQTFSVTPCFEGPMETGTYFSTEGGY 1650 Q + +PC P + G G Y Sbjct: 4097 QGIGQCYDSSPCERQPCQHGATCMPAGEY 4125 Score = 53.5 bits (127), Expect = 2e-06 Identities = 40/169 (23%), Positives = 79/169 (46%), Gaps = 16/169 (9%) Query: 1635 EGPMETGTYFSTEGGYVVLDESFNIGLKF---EIAFEVRPRSSSGTLVH-----GHSVNG 1686 + P + G YF +G F+ L I EVR ++SG L+ G + G Sbjct: 4197 DAPGQYGAYFHDDGFLAFPGHVFSRSLPEVPETIELEVRTSTASGLLLWQGVEVGEAGQG 4256 Query: 1687 -EYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVN 1745 +++++ +++G ++ + G + + + + DG WHR+T +R+ + VD E Sbjct: 4257 KDFISLGLQDGHLVFRYQLGSGE--ARLVSEDPINDGEWHRVTALREGRRGSIQVDGE-- 4312 Query: 1746 HVVGPLNPKP---IDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVI 1791 +V +P P ++ + V++GG P+ S TGC+++ V+ Sbjct: 4313 ELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNLVL 4361 Score = 44.7 bits (104), Expect = 8e-04 Identities = 35/148 (23%), Positives = 59/148 (39%), Gaps = 13/148 (8%) Query: 1485 KSQFSIRLRTRSSHGMIFYVSDQE-----------ENDFMTLFLAHGRLVYMFNVGHKKL 1533 K + I R S+ GM+ Y + + DF++ L GR + F+ G Sbjct: 3685 KFEIKITFRPDSADGMLLYNGQKRVPGSPTNLANRQPDFISFGLVGGRPEFRFDAGSGMA 3744 Query: 1534 KIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPG 1593 IR G +H V +R + G L++ L + + + +YLGG Sbjct: 3745 TIRHPTPLALGHFHTVTLLRSLTQGSLIVGDLAPVNGTSQGKFQGLDLNEELYLGGYPDY 3804 Query: 1594 KAVKNVQINSIYSFSGCLSNLQLNGASI 1621 A+ ++S F GC+ L++ G I Sbjct: 3805 GAIPKAGLSS--GFIGCVRELRIQGEEI 3830 Score = 43.1 bits (100), Expect = 0.002 Identities = 42/174 (24%), Positives = 70/174 (40%), Gaps = 33/174 (18%) Query: 1662 KFEIAFEVRPRSSSGTLVH-------GHSVN-----GEYLNVHMKNGQVIVKVNNGIRDF 1709 KFEI RP S+ G L++ G N ++++ + G+ + + G Sbjct: 3685 KFEIKITFRPDSADGMLLYNGQKRVPGSPTNLANRQPDFISFGLVGGRPEFRFDAG--SG 3742 Query: 1710 STSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNP---------KPIDHRE 1760 ++ L G +H +T++R L +VG L P + +D E Sbjct: 3743 MATIRHPTPLALGHFHTVTLLRSLTQGSL--------IVGDLAPVNGTSQGKFQGLDLNE 3794 Query: 1761 PVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSCP 1814 +++GG P+ P+ S F GC+R I G + F L A I+ CP Sbjct: 3795 ELYLGGYPDYGAIPKAGLSSGFIGCVRELRIQGEEIVFHDLNLT--AHGISHCP 3846 Score = 41.6 bits (96), Expect = 0.007 Identities = 44/190 (23%), Positives = 77/190 (40%), Gaps = 17/190 (8%) Query: 1633 CFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNG---EYL 1689 C EG T S G Y+ L N + + E +P + G L+ +G +++ Sbjct: 3921 CEEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLAPDGVLLFSGGKSGPVEDFV 3980 Query: 1690 NVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVG 1749 ++ M G + + G + + L GRWHR++ R + D VN Sbjct: 3981 SLAMVGGHLEFRYELG--SGLAVLRSAEPLALGRWHRVSAER----LNKDGSLRVNGGRP 4034 Query: 1750 PLNPKP-----IDHREPVFVGGVPESL-LTPRLAPSKPFTGCIRHFVIDGHPVSFSKAAL 1803 L P ++ +++GGV S+ L+P S F GC+ ++G + + + L Sbjct: 4035 VLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFL 4094 Query: 1804 VSGAVSINSC 1813 G+ I C Sbjct: 4095 --GSQGIGQC 4102 Score = 35.0 bits (79), Expect = 0.67 Identities = 31/89 (34%), Positives = 38/89 (42%), Gaps = 21/89 (23%) Query: 208 QCRNCLRNTTGFKCERC------APG--YYGDARIAKNCAVCNCGG--GPCDSVTGECL- 256 +CR C +G CE C PG Y G C+ CNC G CD V G CL Sbjct: 730 ECR-CPIGYSGLSCESCDAHFTRVPGGPYLG------TCSGCNCNGHASSCDPVYGHCLN 782 Query: 257 -EEGFEPPTGCDKC-VWDLTDALRLAALS 283 + E P C+KC DA++ A S Sbjct: 783 CQHNTEGPQ-CNKCKAGFFGDAMKATATS 810 Score = 31.6 bits (70), Expect = 7.4 Identities = 41/188 (21%), Positives = 70/188 (37%), Gaps = 21/188 (11%) Query: 834 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK 893 + V ++T L T Y K +K ++AD +LY G K LA + Sbjct: 3660 ERVVPYFTQTPYSFLPLPTIKDAYRKFEIKITFRPDSADGMLLYNGQKRVPGSPTNLANR 3719 Query: 894 NDNLVYVYNLGTKDVEIPLDS--------KPVSSWPAYFSIVKIERVGKHGKVFLTVPSL 945 + + +G + E D+ P +F V + R G + + Sbjct: 3720 QPDFISFGLVGGRP-EFRFDAGSGMATIRHPTPLALGHFHTVTLLRSLTQGSLIV----- 3773 Query: 946 SSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLN 1005 A +G+F G LDL+ E Y+GG P +P + GF+GC+ + Sbjct: 3774 GDLAPVNGTSQGKFQG----LDLNEE---LYLGGYPDYGAIPKAGLSSGFIGCVRELRIQ 3826 Query: 1006 NDVISLYN 1013 + I ++ Sbjct: 3827 GEEIVFHD 3834 >gi|219842266 usherin isoform B [Homo sapiens] Length = 5202 Score = 106 bits (265), Expect = 2e-22 Identities = 85/357 (23%), Positives = 168/357 (47%), Gaps = 40/357 (11%) Query: 1483 GAKSQFSIRLRTRSSHGMI-FYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQ--- 1538 G K+ F RT+ G+I F S + ++ L L GRL ++F+ +++ + Sbjct: 1543 GIKASF----RTKVPEGLIVFAASPGNQEEYFALQLKKGRLYFLFDPQGSPVEVTTTNDH 1598 Query: 1539 -EKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVK 1597 ++Y+DG WH++I IR ++ G++ +DG+ ++ ++LGG+ + Sbjct: 1599 GKQYSDGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVIGDNTGVFLGGLPRSYTIL 1658 Query: 1598 NVQINSIY-SFSGCLSNLQL----NGASI------TSASQTFSVTPCFEG---PMETGTY 1643 I F GCL ++ N ++I S+ + +V +EG + G Sbjct: 1659 RKDPEIIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQINVYNSWEGCPASLNEGAQ 1718 Query: 1644 FSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNG-EYLNVHMKNGQVIVKV 1702 F G + F+ G+ FEI+F+ R +G L+ ++ +G ++L + +K+G + ++ Sbjct: 1719 FLGAGFLELHPYMFHGGMNFEISFKFRTDQLNGLLLFVYNKDGPDFLAMELKSGILTFRL 1778 Query: 1703 NNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPV 1762 N + + S C+G+W+++ + ++ + + V+ + H +P+ PV Sbjct: 1779 NTSLAFTQVDLLLGLSYCNGKWNKVIIKKEGSFISASVNGLMKH-ASESGDQPLVVNSPV 1837 Query: 1763 FVGGVPESLLT--PRLAPSKPFTGCIRHFVIDGHPVSFSKAALV------SGAVSIN 1811 +VGG+P+ LL L + F GC++ V F++ A+V SGAV +N Sbjct: 1838 YVGGIPQELLNSYQHLCLEQGFGGCMK-------DVKFTRGAVVNLASVSSGAVRVN 1887 Score = 92.4 bits (228), Expect = 4e-18 Identities = 61/219 (27%), Positives = 88/219 (40%), Gaps = 38/219 (17%) Query: 79 CVPCDCNGNSNEC--------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGD--SI 122 C PC CN +S C G G C C+ NTTG +CE C D + + Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631 Query: 123 RGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGS 182 A C+PC C N + C + G +C C + +G C +C G+Y L Sbjct: 632 PSAIDVCKPCDCDTVGTRNGSILCDQIGG--QCNCKRHVSGRQCNQCQNGFYNLQELDPD 689 Query: 183 TCKKCDC--SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGY-----YGDARIA 235 C C+C SG D ++ C + +GQC+ C N G +C+ C G+ + D Sbjct: 690 GCSPCNCNTSGTVDGDI---TCHQNSGQCK-CKANVIGLRCDHCNFGFKFLRSFNDV--- 742 Query: 236 KNCAVCNCG-----GGPCDSVTGECLEEGFEPPTGCDKC 269 C C C C+ +G+C + CD C Sbjct: 743 -GCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTC 780 Score = 87.8 bits (216), Expect = 9e-17 Identities = 66/230 (28%), Positives = 98/230 (42%), Gaps = 47/230 (20%) Query: 74 TLSGECVPCDCNGNSNEC-LDGSGYCVHCQRN--TTGEHCEKCLDGYIGDSIRGAPQF-- 128 T+SG C C+G+++ C Y C + T G HC++CL Y R Q Sbjct: 513 TISGRC---QCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569 Query: 129 --CQPCPCPLPHLANFAESC-------------YRKNGAVRCICNENYAGPNCERCAPGY 173 C+PC C + ++SC +R G V C N G NCE C + Sbjct: 570 FNCKPCQC-----NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYF 624 Query: 174 Y----GNPLLIGSTCKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG 227 + +P I CK CDC G + +++ CD++ GQC NC R+ +G +C +C G Sbjct: 625 FRQVGADPSAI-DVCKPCDCDTVGTRNGSIL---CDQIGGQC-NCKRHVSGRQCNQCQNG 679 Query: 228 YYGDARI-AKNCAVCNC-------GGGPCDSVTGECLEEGFEPPTGCDKC 269 +Y + C+ CNC G C +G+C + CD C Sbjct: 680 FYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHC 729 Score = 87.0 bits (214), Expect = 1e-16 Identities = 65/224 (29%), Positives = 95/224 (42%), Gaps = 35/224 (15%) Query: 65 EKCNAGFFHTLSGE---CVPCDCN--GNSNE-CLDGSGYCVHCQRNTTGEHCEKCLDGYI 118 + CN GF S C PC CN G+ N+ C SG C C++ G C+ C + + Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAKGLQCDTCRENFY 785 Query: 119 GDSIRGAPQFCQPCPC----PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174 G + C+ C C LP C K G +CIC N G C +C G + Sbjct: 786 GLDVTN----CKACDCDTAGSLP-----GTVCNAKTG--QCICKPNVEGRQCNKCLEGNF 834 Query: 175 GNPLLIGSTCKKCDC--SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-D 231 C C+C +G + +L+ C++ TGQC C TG +C +C P Y Sbjct: 835 YLRQNNSFLCLPCNCDKTGTINGSLL---CNKSTGQC-PCKLGVTGLRCNQCEPHRYNLT 890 Query: 232 ARIAKNCAVCNCG------GGPCDSVTGECLEEGFEPPTGCDKC 269 ++C +C C G CD ++G+CL C++C Sbjct: 891 IDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQC 934 Score = 87.0 bits (214), Expect = 1e-16 Identities = 66/222 (29%), Positives = 91/222 (40%), Gaps = 30/222 (13%) Query: 66 KCNAGFFHTLSGE---CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117 KC G F+ C+PC+C+ S C +G C C+ TG C +C Sbjct: 828 KCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCP-CKLGVTGLRCNQCEPHR 886 Query: 118 IGDSIRGAPQFCQPCPCP----LPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGY 173 +I Q CQ C C LP C +G +C+C N G C +C PG+ Sbjct: 887 YNLTIDNF-QHCQMCECDSLGTLP-----GTICDPISG--QCLCVPNRQGRRCNQCQPGF 938 Query: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR 233 Y +P + C C C N I C+ +TGQC + G +C++C Y+G Sbjct: 939 YISPGN-ATGCLPCSCHTTGAVNHI---CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDP 994 Query: 234 IAKNCAVCNCG-----GGPCDSVTGECLEEGFEPPTGCDKCV 270 C CNC C VTG+C + F + CD CV Sbjct: 995 QTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036 Score = 66.6 bits (161), Expect = 2e-10 Identities = 48/153 (31%), Positives = 65/153 (42%), Gaps = 17/153 (11%) Query: 79 CVPCDCNG----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPC 134 C C+C+ C SG C+ C N G C +C G+ G C PC C Sbjct: 897 CQMCECDSLGTLPGTICDPISGQCL-CVPNRQGRRCNQCQPGFYISP--GNATGCLPCSC 953 Query: 135 PLPHLANFAESCYRKNGAVRCICNE-NYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNS 193 N C G +C+C + + AG C++C Y+G G C+ C+C + Sbjct: 954 HTTGAVNHI--CNSLTG--QCVCQDASIAGQRCDQCKDHYFGFDPQTGR-CQPCNCHLSG 1008 Query: 194 DPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226 N E C VTGQC C + TG KC+ C P Sbjct: 1009 ALN---ETCHLVTGQCF-CKQFVTGSKCDACVP 1037 Score = 59.7 bits (143), Expect = 3e-08 Identities = 35/112 (31%), Positives = 52/112 (46%), Gaps = 13/112 (11%) Query: 66 KCNAGFFHTLSGE--CVPCDCNGN---SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG- 119 +C GF+ + C+PC C+ ++ C +G CV + G+ C++C D Y G Sbjct: 933 QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992 Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAP 171 D G CQPC C L N E+C+ G +C C + G C+ C P Sbjct: 993 DPQTGR---CQPCNCHLSGALN--ETCHLVTG--QCFCKQFVTGSKCDACVP 1037 Score = 56.2 bits (134), Expect = 3e-07 Identities = 74/269 (27%), Positives = 103/269 (38%), Gaps = 49/269 (18%) Query: 1045 FDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMV---NGSMFFRLEMRNGYLH 1101 F G+GY T T RT GLI+ N +F L+++ G L+ Sbjct: 1522 FIGNGYCKFPSSTHPVNT-DFTGIKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLY 1580 Query: 1102 VFYDFGFSGGPVHLEDTLKKA-QINDAKYHEISIIYHNDKKMILVVDRRHVKS---MDNE 1157 +D G PV + T Q +D K+HEI I H I +D + S ++ Sbjct: 1581 FLFDP--QGSPVEVTTTNDHGKQYSDGKWHEIIAIRHQAFGQI-TLDGIYTGSSAILNGS 1637 Query: 1158 KMKIPFTDIYIGGAP---------PEILQSRALRAHLPLDINFRGCMKGFQFQKK----- 1203 + T +++GG P PEI+Q F GC+K F K Sbjct: 1638 TVIGDNTGVFLGGLPRSYTILRKDPEIIQK-----------GFVGCLKDVHFMKNYNPSA 1686 Query: 1204 -----DFNLLE-QTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDG--FEGGFN 1255 D+ E Q GCP ++ A F G F+ + F G FE F Sbjct: 1687 IWEPLDWQSSEEQINVYNSWEGCPAS--LNEGAQFLGAGFL-ELHPYMFHGGMNFEISFK 1743 Query: 1256 FRTLQPNGLLF--YYASGSDVFSISLDNG 1282 FRT Q NGLL Y G D ++ L +G Sbjct: 1744 FRTDQLNGLLLFVYNKDGPDFLAMELKSG 1772 Score = 51.6 bits (122), Expect = 7e-06 Identities = 70/356 (19%), Positives = 144/356 (40%), Gaps = 44/356 (12%) Query: 862 VKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWP 921 +K T+ + I++ S ++EY L +K L ++++ Sbjct: 1544 IKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLYFLFD------------------- 1584 Query: 922 AYFSIVKIERVGKHGKVFL-----TVPSLSSTAEEKFIKKGEFSGDDSLLD---LDPEDT 973 S V++ HGK + + ++ A + G ++G ++L+ + ++T Sbjct: 1585 PQGSPVEVTTTNDHGKQYSDGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVIGDNT 1644 Query: 974 VFYVGGVPSNFKL---PTSLNLPGFVGCLELATL--NNDVISLYNFKHIYNMDPSTSVPC 1028 ++GG+P ++ + + GFVGCL+ N + +++ + + +V Sbjct: 1645 GVFLGGLPRSYTILRKDPEIIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQINVYN 1704 Query: 1029 ARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVN-- 1086 + + + + A + G+G+ + G G + RT NGL+L + N Sbjct: 1705 SWEGCPASLNEGAQFL--GAGFLELHPYMFHG--GMNFEISFKFRTDQLNGLLLFVYNKD 1760 Query: 1087 GSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVV 1146 G F +E+++G L + + V D L + K++++ I V Sbjct: 1761 GPDFLAMELKSGILTFRLNTSLAFTQV---DLLLGLSYCNGKWNKVIIKKEGSFISASVN 1817 Query: 1147 DRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQK 1202 S ++ + + +Y+GG P E+L S HL L+ F GCMK +F + Sbjct: 1818 GLMKHASESGDQPLVVNSPVYVGGIPQELLNS---YQHLCLEQGFGGCMKDVKFTR 1870 >gi|93204871 netrin 4 [Homo sapiens] Length = 628 Score = 102 bits (255), Expect = 3e-21 Identities = 73/249 (29%), Positives = 100/249 (40%), Gaps = 47/249 (18%) Query: 82 CDCNGNSNECLD----------GSGYCVH----CQRNTTGEHCEKCLDGY------IGDS 121 C CNG++++C+ G+ + VH C+ NT G HC+ C Y D Sbjct: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADG 321 Query: 122 IRGAPQFCQPCPC----PLPHL-ANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176 GAP C+ C C H N E+ ++G V C N G C+RC PG+Y + Sbjct: 322 KTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRD 381 Query: 177 ---PLLIGSTCKKCDCSGNSD---PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG 230 P CK C C P CD G C C G +C+RC GY+G Sbjct: 382 LRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC-PCKPGVAGRRCDRCMVGYWG 440 Query: 231 DARIAKNCAVCNCGGGPCDSVTGECLEE-----------GFEPPTGCDKCVWDLTDALRL 279 C C+C G CD +TG+C+ F P + W+ DA Sbjct: 441 FGDY--GCRPCDCAGS-CDPITGDCISSHTDIDWYHEVPDFRPVHNKSEPAWEWEDAQGF 497 Query: 280 AALSIEEGK 288 +AL + GK Sbjct: 498 SAL-LHSGK 505 Score = 86.7 bits (213), Expect = 2e-16 Identities = 52/151 (34%), Positives = 67/151 (44%), Gaps = 35/151 (23%) Query: 78 ECVPCDCNGNSNECL-----------DGSGYCVHCQRNTTGEHCEKCLDGYIGDSIR--G 124 EC C CNG+++ C G C CQ NT G++C++C G+ D R Sbjct: 328 ECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFS 387 Query: 125 APQFCQPCPC------PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 178 AP C+PC C LP AN C NG C C AG C+RC GY+G Sbjct: 388 APDACKPCSCHPVGSAVLP--ANSVTFCDPSNG--DCPCKPGVAGRRCDRCMVGYWG--- 440 Query: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQC 209 C+ CDC+G+ CD +TG C Sbjct: 441 FGDYGCRPCDCAGS---------CDPITGDC 462 >gi|62868217 laminin, beta 3 precursor [Homo sapiens] Length = 1172 Score = 99.8 bits (247), Expect = 2e-20 Identities = 67/202 (33%), Positives = 92/202 (45%), Gaps = 26/202 (12%) Query: 78 ECVPCDCNGNSNEC---------LDGS--GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126 EC CDCNG+S C G+ G C +C+ +T G++CE+C Y + GA Sbjct: 312 ECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGAS 371 Query: 127 --QFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184 + C C C P A C G +C+C E+ G C+ C PG+ G C Sbjct: 372 IQETCISCECD-PDGAVPGAPCDPVTG--QCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428 Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244 +CDC N + CDE +G+C CL N G KC++CAP Y+ + C C C Sbjct: 429 HRCDC--NILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACD 484 Query: 245 -----GGPCDSVTGEC-LEEGF 260 C+ TG+C EGF Sbjct: 485 PHNSLSPQCNQFTGQCPCREGF 506 Score = 93.2 bits (230), Expect = 2e-18 Identities = 175/784 (22%), Positives = 297/784 (37%), Gaps = 134/784 (17%) Query: 79 CVPCDCN--GNSNE--CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPC 134 C CDCN G+ + C + SG C+ C N G C++C Y G Q C+PC C Sbjct: 428 CHRCDCNILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASG--QGCEPCAC 483 Query: 135 PLPHLANFAESCYRKNGAVRCICNENYAGPNCE-----RCAPGYYGNPLLIGSTCKKCDC 189 PH + + C + G +C C E + G C +C YG+ + + C+ CDC Sbjct: 484 D-PH-NSLSPQCNQFTG--QCPCREGFGGLMCSAAAIRQCPDRTYGD---VATGCRACDC 536 Query: 190 S--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGP 247 G P CD+ +G+C C TG +C++C GY + C C+ P Sbjct: 537 DFRGTEGPG-----CDKASGRCL-CRPGLTGPRCDQCQRGYCNRYPV---CVACH----P 583 Query: 248 CDSVTGECLEE---GFEPPTGCDKCVWD---LTDALRLAALSIEEGKSGVLSV----SSG 297 C L E F +W L D R A I + KS + + SS Sbjct: 584 CFQTYDADLREQALRFGRLRNATASLWSGPGLED--RGLASRILDAKSKIEQIRAVLSSP 641 Query: 298 AAAHRHVNEINATIYLLKTKLS--------ERENQYALRKIQ-INNAENTMKSLLSDVEE 348 A + V ++ + I L+ L E E R ++ ++ + N + ++ E Sbjct: 642 AVTEQEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKRE 701 Query: 349 LVEKENQASRKGQL--------VQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGE 400 EK + A G ++ ++ +S+L++Q D R + + + + G Sbjct: 702 QFEKISSADPSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGG 761 Query: 401 EHELSPKEISEKLVLAQKMLEEIRSRQPFFTQ-----RELVDEEADEAYELLSQAESWQR 455 S KLV + + + P F + R++ EL Q ++ Sbjct: 762 TG-------SPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQ-DNGTA 813 Query: 456 LHNETRTLFP----------VVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAAR 505 + R + P V EQL +NA+L ++ +R AE+ + Sbjct: 814 CGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQ-------MIRAAEESASQIQSS 866 Query: 506 QRDHEKQQERVREQMEV----VNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGA 561 + E Q R QME + + D LT P + + ++ + ++ D A Sbjct: 867 AQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSA 926 Query: 562 -----KSELQVKLSNLSNLSHDLVQ--EAIDHAQDLQQEANELSRKLHSSDMNGLVQKAL 614 +E+Q + L N+ L Q + I A+ LQ EA E + H+ + G V+ + Sbjct: 927 TVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHA--VEGQVEDVV 984 Query: 615 DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQA 674 N+ + V + EA +T + + I D V+ + + + ++ Q + Sbjct: 985 --GNLRQGTV-ALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWT 1041 Query: 675 KAESSSDEAVADTSRRVGGALARKSALKTRLS-----DAVKQLQAAERGDAQQRLGQSRL 729 + E +A + V + A + LS + +KQ A + + RLGQS + Sbjct: 1042 RMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYA----ELKDRLGQSSM 1097 Query: 730 ITEEANR-------------TTMEVQQATAPMANNLTNWSQ--NLQHFDSSAYNTAVNSA 774 + E+ R TME+ M L SQ L+ D + V Sbjct: 1098 LGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQI 1157 Query: 775 RDAV 778 RD + Sbjct: 1158 RDHI 1161 Score = 92.0 bits (227), Expect = 5e-18 Identities = 50/135 (37%), Positives = 63/135 (46%), Gaps = 20/135 (14%) Query: 155 CICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNLIFEDCDE 204 C+C N AGPNCERCAP Y P C++CDC+G+S DP + Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338 Query: 205 VTGQCRNCLRNTTGFKCERCAPGYYGDAR----IAKNCAVCNCG------GGPCDSVTGE 254 G C NC +T G CERC Y+ + R I + C C C G PCD VTG+ Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398 Query: 255 CLEEGFEPPTGCDKC 269 C+ + CD C Sbjct: 399 CVCKEHVQGERCDLC 413 Score = 84.3 bits (207), Expect = 1e-15 Identities = 67/225 (29%), Positives = 90/225 (40%), Gaps = 46/225 (20%) Query: 82 CDCNGNSNECLDGSG-------------YCVHCQRNTTGEHCEKCLDGYIGDSIRGA--- 125 C C+G+++ C G CV CQ NT G +CE+C Y R A Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308 Query: 126 -PQFCQPCPCPLPHLANFAESCY----------RKNGAVRCICNENYAGPNCERCAPGYY 174 CQ C C +E+C+ G V C ++ G NCERC Y+ Sbjct: 309 DAHECQRCDC-----NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363 Query: 175 GN---PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG- 230 N I TC C+C + D + CD VTGQC C + G +C+ C PG+ G Sbjct: 364 RNRRPGASIQETCISCEC--DPDGAVPGAPCDPVTGQC-VCKEHVQGERCDLCKPGFTGL 420 Query: 231 DARIAKNCAVCNCG------GGPCDSVTGECLEEGFEPPTGCDKC 269 + C C+C PCD +G CL CD+C Sbjct: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQC 465 Score = 49.7 bits (117), Expect = 3e-05 Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 18/121 (14%) Query: 62 PAAEKCNAGFFHTLSGE-CVPCDC---NGNSNECLDGSGYCVHCQRNTTGEHCE-----K 112 P ++C + SG+ C PC C N S +C +G C C+ G C + Sbjct: 460 PKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCP-CREGFGGLMCSAAAIRQ 518 Query: 113 CLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172 C D GD G C+ C C C + +G RC+C GP C++C G Sbjct: 519 CPDRTYGDVATG----CRACDCDFR--GTEGPGCDKASG--RCLCRPGLTGPRCDQCQRG 570 Query: 173 Y 173 Y Sbjct: 571 Y 571 >gi|62868215 laminin, beta 3 precursor [Homo sapiens] Length = 1172 Score = 99.8 bits (247), Expect = 2e-20 Identities = 67/202 (33%), Positives = 92/202 (45%), Gaps = 26/202 (12%) Query: 78 ECVPCDCNGNSNEC---------LDGS--GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126 EC CDCNG+S C G+ G C +C+ +T G++CE+C Y + GA Sbjct: 312 ECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGAS 371 Query: 127 --QFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184 + C C C P A C G +C+C E+ G C+ C PG+ G C Sbjct: 372 IQETCISCECD-PDGAVPGAPCDPVTG--QCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428 Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244 +CDC N + CDE +G+C CL N G KC++CAP Y+ + C C C Sbjct: 429 HRCDC--NILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACD 484 Query: 245 -----GGPCDSVTGEC-LEEGF 260 C+ TG+C EGF Sbjct: 485 PHNSLSPQCNQFTGQCPCREGF 506 Score = 93.2 bits (230), Expect = 2e-18 Identities = 175/784 (22%), Positives = 297/784 (37%), Gaps = 134/784 (17%) Query: 79 CVPCDCN--GNSNE--CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPC 134 C CDCN G+ + C + SG C+ C N G C++C Y G Q C+PC C Sbjct: 428 CHRCDCNILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASG--QGCEPCAC 483 Query: 135 PLPHLANFAESCYRKNGAVRCICNENYAGPNCE-----RCAPGYYGNPLLIGSTCKKCDC 189 PH + + C + G +C C E + G C +C YG+ + + C+ CDC Sbjct: 484 D-PH-NSLSPQCNQFTG--QCPCREGFGGLMCSAAAIRQCPDRTYGD---VATGCRACDC 536 Query: 190 S--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGP 247 G P CD+ +G+C C TG +C++C GY + C C+ P Sbjct: 537 DFRGTEGPG-----CDKASGRCL-CRPGLTGPRCDQCQRGYCNRYPV---CVACH----P 583 Query: 248 CDSVTGECLEE---GFEPPTGCDKCVWD---LTDALRLAALSIEEGKSGVLSV----SSG 297 C L E F +W L D R A I + KS + + SS Sbjct: 584 CFQTYDADLREQALRFGRLRNATASLWSGPGLED--RGLASRILDAKSKIEQIRAVLSSP 641 Query: 298 AAAHRHVNEINATIYLLKTKLS--------ERENQYALRKIQ-INNAENTMKSLLSDVEE 348 A + V ++ + I L+ L E E R ++ ++ + N + ++ E Sbjct: 642 AVTEQEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKRE 701 Query: 349 LVEKENQASRKGQL--------VQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGE 400 EK + A G ++ ++ +S+L++Q D R + + + + G Sbjct: 702 QFEKISSADPSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGG 761 Query: 401 EHELSPKEISEKLVLAQKMLEEIRSRQPFFTQ-----RELVDEEADEAYELLSQAESWQR 455 S KLV + + + P F + R++ EL Q ++ Sbjct: 762 TG-------SPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQ-DNGTA 813 Query: 456 LHNETRTLFP----------VVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAAR 505 + R + P V EQL +NA+L ++ +R AE+ + Sbjct: 814 CGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQ-------MIRAAEESASQIQSS 866 Query: 506 QRDHEKQQERVREQMEV----VNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGA 561 + E Q R QME + + D LT P + + ++ + ++ D A Sbjct: 867 AQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSA 926 Query: 562 -----KSELQVKLSNLSNLSHDLVQ--EAIDHAQDLQQEANELSRKLHSSDMNGLVQKAL 614 +E+Q + L N+ L Q + I A+ LQ EA E + H+ + G V+ + Sbjct: 927 TVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHA--VEGQVEDVV 984 Query: 615 DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQA 674 N+ + V + EA +T + + I D V+ + + + ++ Q + Sbjct: 985 --GNLRQGTV-ALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWT 1041 Query: 675 KAESSSDEAVADTSRRVGGALARKSALKTRLS-----DAVKQLQAAERGDAQQRLGQSRL 729 + E +A + V + A + LS + +KQ A + + RLGQS + Sbjct: 1042 RMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYA----ELKDRLGQSSM 1097 Query: 730 ITEEANR-------------TTMEVQQATAPMANNLTNWSQ--NLQHFDSSAYNTAVNSA 774 + E+ R TME+ M L SQ L+ D + V Sbjct: 1098 LGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQI 1157 Query: 775 RDAV 778 RD + Sbjct: 1158 RDHI 1161 Score = 92.0 bits (227), Expect = 5e-18 Identities = 50/135 (37%), Positives = 63/135 (46%), Gaps = 20/135 (14%) Query: 155 CICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNLIFEDCDE 204 C+C N AGPNCERCAP Y P C++CDC+G+S DP + Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338 Query: 205 VTGQCRNCLRNTTGFKCERCAPGYYGDAR----IAKNCAVCNCG------GGPCDSVTGE 254 G C NC +T G CERC Y+ + R I + C C C G PCD VTG+ Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398 Query: 255 CLEEGFEPPTGCDKC 269 C+ + CD C Sbjct: 399 CVCKEHVQGERCDLC 413 Score = 84.3 bits (207), Expect = 1e-15 Identities = 67/225 (29%), Positives = 90/225 (40%), Gaps = 46/225 (20%) Query: 82 CDCNGNSNECLDGSG-------------YCVHCQRNTTGEHCEKCLDGYIGDSIRGA--- 125 C C+G+++ C G CV CQ NT G +CE+C Y R A Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308 Query: 126 -PQFCQPCPCPLPHLANFAESCY----------RKNGAVRCICNENYAGPNCERCAPGYY 174 CQ C C +E+C+ G V C ++ G NCERC Y+ Sbjct: 309 DAHECQRCDC-----NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363 Query: 175 GN---PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG- 230 N I TC C+C + D + CD VTGQC C + G +C+ C PG+ G Sbjct: 364 RNRRPGASIQETCISCEC--DPDGAVPGAPCDPVTGQC-VCKEHVQGERCDLCKPGFTGL 420 Query: 231 DARIAKNCAVCNCG------GGPCDSVTGECLEEGFEPPTGCDKC 269 + C C+C PCD +G CL CD+C Sbjct: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQC 465 Score = 49.7 bits (117), Expect = 3e-05 Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 18/121 (14%) Query: 62 PAAEKCNAGFFHTLSGE-CVPCDC---NGNSNECLDGSGYCVHCQRNTTGEHCE-----K 112 P ++C + SG+ C PC C N S +C +G C C+ G C + Sbjct: 460 PKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCP-CREGFGGLMCSAAAIRQ 518 Query: 113 CLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172 C D GD G C+ C C C + +G RC+C GP C++C G Sbjct: 519 CPDRTYGDVATG----CRACDCDFR--GTEGPGCDKASG--RCLCRPGLTGPRCDQCQRG 570 Query: 173 Y 173 Y Sbjct: 571 Y 571 >gi|189083719 laminin, beta 3 precursor [Homo sapiens] Length = 1172 Score = 99.8 bits (247), Expect = 2e-20 Identities = 67/202 (33%), Positives = 92/202 (45%), Gaps = 26/202 (12%) Query: 78 ECVPCDCNGNSNEC---------LDGS--GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126 EC CDCNG+S C G+ G C +C+ +T G++CE+C Y + GA Sbjct: 312 ECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGAS 371 Query: 127 --QFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184 + C C C P A C G +C+C E+ G C+ C PG+ G C Sbjct: 372 IQETCISCECD-PDGAVPGAPCDPVTG--QCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428 Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244 +CDC N + CDE +G+C CL N G KC++CAP Y+ + C C C Sbjct: 429 HRCDC--NILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACD 484 Query: 245 -----GGPCDSVTGEC-LEEGF 260 C+ TG+C EGF Sbjct: 485 PHNSLSPQCNQFTGQCPCREGF 506 Score = 93.2 bits (230), Expect = 2e-18 Identities = 175/784 (22%), Positives = 297/784 (37%), Gaps = 134/784 (17%) Query: 79 CVPCDCN--GNSNE--CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPC 134 C CDCN G+ + C + SG C+ C N G C++C Y G Q C+PC C Sbjct: 428 CHRCDCNILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASG--QGCEPCAC 483 Query: 135 PLPHLANFAESCYRKNGAVRCICNENYAGPNCE-----RCAPGYYGNPLLIGSTCKKCDC 189 PH + + C + G +C C E + G C +C YG+ + + C+ CDC Sbjct: 484 D-PH-NSLSPQCNQFTG--QCPCREGFGGLMCSAAAIRQCPDRTYGD---VATGCRACDC 536 Query: 190 S--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGP 247 G P CD+ +G+C C TG +C++C GY + C C+ P Sbjct: 537 DFRGTEGPG-----CDKASGRCL-CRPGLTGPRCDQCQRGYCNRYPV---CVACH----P 583 Query: 248 CDSVTGECLEE---GFEPPTGCDKCVWD---LTDALRLAALSIEEGKSGVLSV----SSG 297 C L E F +W L D R A I + KS + + SS Sbjct: 584 CFQTYDADLREQALRFGRLRNATASLWSGPGLED--RGLASRILDAKSKIEQIRAVLSSP 641 Query: 298 AAAHRHVNEINATIYLLKTKLS--------ERENQYALRKIQ-INNAENTMKSLLSDVEE 348 A + V ++ + I L+ L E E R ++ ++ + N + ++ E Sbjct: 642 AVTEQEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKRE 701 Query: 349 LVEKENQASRKGQL--------VQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGE 400 EK + A G ++ ++ +S+L++Q D R + + + + G Sbjct: 702 QFEKISSADPSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGG 761 Query: 401 EHELSPKEISEKLVLAQKMLEEIRSRQPFFTQ-----RELVDEEADEAYELLSQAESWQR 455 S KLV + + + P F + R++ EL Q ++ Sbjct: 762 TG-------SPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQ-DNGTA 813 Query: 456 LHNETRTLFP----------VVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAAR 505 + R + P V EQL +NA+L ++ +R AE+ + Sbjct: 814 CGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQ-------MIRAAEESASQIQSS 866 Query: 506 QRDHEKQQERVREQMEV----VNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGA 561 + E Q R QME + + D LT P + + ++ + ++ D A Sbjct: 867 AQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSA 926 Query: 562 -----KSELQVKLSNLSNLSHDLVQ--EAIDHAQDLQQEANELSRKLHSSDMNGLVQKAL 614 +E+Q + L N+ L Q + I A+ LQ EA E + H+ + G V+ + Sbjct: 927 TVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHA--VEGQVEDVV 984 Query: 615 DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQA 674 N+ + V + EA +T + + I D V+ + + + ++ Q + Sbjct: 985 --GNLRQGTV-ALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWT 1041 Query: 675 KAESSSDEAVADTSRRVGGALARKSALKTRLS-----DAVKQLQAAERGDAQQRLGQSRL 729 + E +A + V + A + LS + +KQ A + + RLGQS + Sbjct: 1042 RMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYA----ELKDRLGQSSM 1097 Query: 730 ITEEANR-------------TTMEVQQATAPMANNLTNWSQ--NLQHFDSSAYNTAVNSA 774 + E+ R TME+ M L SQ L+ D + V Sbjct: 1098 LGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQI 1157 Query: 775 RDAV 778 RD + Sbjct: 1158 RDHI 1161 Score = 92.0 bits (227), Expect = 5e-18 Identities = 50/135 (37%), Positives = 63/135 (46%), Gaps = 20/135 (14%) Query: 155 CICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNLIFEDCDE 204 C+C N AGPNCERCAP Y P C++CDC+G+S DP + Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338 Query: 205 VTGQCRNCLRNTTGFKCERCAPGYYGDAR----IAKNCAVCNCG------GGPCDSVTGE 254 G C NC +T G CERC Y+ + R I + C C C G PCD VTG+ Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398 Query: 255 CLEEGFEPPTGCDKC 269 C+ + CD C Sbjct: 399 CVCKEHVQGERCDLC 413 Score = 84.3 bits (207), Expect = 1e-15 Identities = 67/225 (29%), Positives = 90/225 (40%), Gaps = 46/225 (20%) Query: 82 CDCNGNSNECLDGSG-------------YCVHCQRNTTGEHCEKCLDGYIGDSIRGA--- 125 C C+G+++ C G CV CQ NT G +CE+C Y R A Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308 Query: 126 -PQFCQPCPCPLPHLANFAESCY----------RKNGAVRCICNENYAGPNCERCAPGYY 174 CQ C C +E+C+ G V C ++ G NCERC Y+ Sbjct: 309 DAHECQRCDC-----NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363 Query: 175 GN---PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG- 230 N I TC C+C + D + CD VTGQC C + G +C+ C PG+ G Sbjct: 364 RNRRPGASIQETCISCEC--DPDGAVPGAPCDPVTGQC-VCKEHVQGERCDLCKPGFTGL 420 Query: 231 DARIAKNCAVCNCG------GGPCDSVTGECLEEGFEPPTGCDKC 269 + C C+C PCD +G CL CD+C Sbjct: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQC 465 Score = 49.7 bits (117), Expect = 3e-05 Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 18/121 (14%) Query: 62 PAAEKCNAGFFHTLSGE-CVPCDC---NGNSNECLDGSGYCVHCQRNTTGEHCE-----K 112 P ++C + SG+ C PC C N S +C +G C C+ G C + Sbjct: 460 PKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCP-CREGFGGLMCSAAAIRQ 518 Query: 113 CLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172 C D GD G C+ C C C + +G RC+C GP C++C G Sbjct: 519 CPDRTYGDVATG----CRACDCDFR--GTEGPGCDKASG--RCLCRPGLTGPRCDQCQRG 570 Query: 173 Y 173 Y Sbjct: 571 Y 571 >gi|219842259 usherin isoform A [Homo sapiens] Length = 1546 Score = 92.4 bits (228), Expect = 4e-18 Identities = 61/219 (27%), Positives = 88/219 (40%), Gaps = 38/219 (17%) Query: 79 CVPCDCNGNSNEC--------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGD--SI 122 C PC CN +S C G G C C+ NTTG +CE C D + + Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631 Query: 123 RGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGS 182 A C+PC C N + C + G +C C + +G C +C G+Y L Sbjct: 632 PSAIDVCKPCDCDTVGTRNGSILCDQIGG--QCNCKRHVSGRQCNQCQNGFYNLQELDPD 689 Query: 183 TCKKCDC--SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGY-----YGDARIA 235 C C+C SG D ++ C + +GQC+ C N G +C+ C G+ + D Sbjct: 690 GCSPCNCNTSGTVDGDI---TCHQNSGQCK-CKANVIGLRCDHCNFGFKFLRSFNDV--- 742 Query: 236 KNCAVCNCG-----GGPCDSVTGECLEEGFEPPTGCDKC 269 C C C C+ +G+C + CD C Sbjct: 743 -GCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTC 780 Score = 87.8 bits (216), Expect = 9e-17 Identities = 66/230 (28%), Positives = 98/230 (42%), Gaps = 47/230 (20%) Query: 74 TLSGECVPCDCNGNSNEC-LDGSGYCVHCQRN--TTGEHCEKCLDGYIGDSIRGAPQF-- 128 T+SG C C+G+++ C Y C + T G HC++CL Y R Q Sbjct: 513 TISGRC---QCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569 Query: 129 --CQPCPCPLPHLANFAESC-------------YRKNGAVRCICNENYAGPNCERCAPGY 173 C+PC C + ++SC +R G V C N G NCE C + Sbjct: 570 FNCKPCQC-----NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYF 624 Query: 174 Y----GNPLLIGSTCKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG 227 + +P I CK CDC G + +++ CD++ GQC NC R+ +G +C +C G Sbjct: 625 FRQVGADPSAI-DVCKPCDCDTVGTRNGSIL---CDQIGGQC-NCKRHVSGRQCNQCQNG 679 Query: 228 YYGDARI-AKNCAVCNC-------GGGPCDSVTGECLEEGFEPPTGCDKC 269 +Y + C+ CNC G C +G+C + CD C Sbjct: 680 FYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHC 729 Score = 87.0 bits (214), Expect = 1e-16 Identities = 65/224 (29%), Positives = 95/224 (42%), Gaps = 35/224 (15%) Query: 65 EKCNAGFFHTLSGE---CVPCDCN--GNSNE-CLDGSGYCVHCQRNTTGEHCEKCLDGYI 118 + CN GF S C PC CN G+ N+ C SG C C++ G C+ C + + Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAKGLQCDTCRENFY 785 Query: 119 GDSIRGAPQFCQPCPC----PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174 G + C+ C C LP C K G +CIC N G C +C G + Sbjct: 786 GLDVTN----CKACDCDTAGSLP-----GTVCNAKTG--QCICKPNVEGRQCNKCLEGNF 834 Query: 175 GNPLLIGSTCKKCDC--SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-D 231 C C+C +G + +L+ C++ TGQC C TG +C +C P Y Sbjct: 835 YLRQNNSFLCLPCNCDKTGTINGSLL---CNKSTGQC-PCKLGVTGLRCNQCEPHRYNLT 890 Query: 232 ARIAKNCAVCNCG------GGPCDSVTGECLEEGFEPPTGCDKC 269 ++C +C C G CD ++G+CL C++C Sbjct: 891 IDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQC 934 Score = 87.0 bits (214), Expect = 1e-16 Identities = 66/222 (29%), Positives = 91/222 (40%), Gaps = 30/222 (13%) Query: 66 KCNAGFFHTLSGE---CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117 KC G F+ C+PC+C+ S C +G C C+ TG C +C Sbjct: 828 KCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCP-CKLGVTGLRCNQCEPHR 886 Query: 118 IGDSIRGAPQFCQPCPCP----LPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGY 173 +I Q CQ C C LP C +G +C+C N G C +C PG+ Sbjct: 887 YNLTIDNF-QHCQMCECDSLGTLP-----GTICDPISG--QCLCVPNRQGRRCNQCQPGF 938 Query: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR 233 Y +P + C C C N I C+ +TGQC + G +C++C Y+G Sbjct: 939 YISPGN-ATGCLPCSCHTTGAVNHI---CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDP 994 Query: 234 IAKNCAVCNCG-----GGPCDSVTGECLEEGFEPPTGCDKCV 270 C CNC C VTG+C + F + CD CV Sbjct: 995 QTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036 Score = 66.6 bits (161), Expect = 2e-10 Identities = 48/153 (31%), Positives = 65/153 (42%), Gaps = 17/153 (11%) Query: 79 CVPCDCNG----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPC 134 C C+C+ C SG C+ C N G C +C G+ G C PC C Sbjct: 897 CQMCECDSLGTLPGTICDPISGQCL-CVPNRQGRRCNQCQPGFYISP--GNATGCLPCSC 953 Query: 135 PLPHLANFAESCYRKNGAVRCICNE-NYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNS 193 N C G +C+C + + AG C++C Y+G G C+ C+C + Sbjct: 954 HTTGAVNHI--CNSLTG--QCVCQDASIAGQRCDQCKDHYFGFDPQTGR-CQPCNCHLSG 1008 Query: 194 DPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226 N E C VTGQC C + TG KC+ C P Sbjct: 1009 ALN---ETCHLVTGQCF-CKQFVTGSKCDACVP 1037 Score = 59.7 bits (143), Expect = 3e-08 Identities = 35/112 (31%), Positives = 52/112 (46%), Gaps = 13/112 (11%) Query: 66 KCNAGFFHTLSGE--CVPCDCNGN---SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG- 119 +C GF+ + C+PC C+ ++ C +G CV + G+ C++C D Y G Sbjct: 933 QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992 Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAP 171 D G CQPC C L N E+C+ G +C C + G C+ C P Sbjct: 993 DPQTGR---CQPCNCHLSGALN--ETCHLVTG--QCFCKQFVTGSKCDACVP 1037 >gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens] Length = 1547 Score = 87.4 bits (215), Expect = 1e-16 Identities = 163/849 (19%), Positives = 315/849 (37%), Gaps = 136/849 (16%) Query: 1045 FDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFY 1104 F GS Y D+++ + +T NGL+L + + L ++NG + + Sbjct: 319 FKGSEYFCY-DLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVI 377 Query: 1105 DFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMIL---VVDRRHVK---SMDNEK 1158 + G +E + ND +H++ + + + + +V++ H S+D Sbjct: 378 NLGSGAFEALVEPV--NGKFNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGIL 435 Query: 1159 MKIPFTD-----------IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNL 1207 +T Y+GG+P S A P+ NF GC+K ++ D L Sbjct: 436 TTTGYTQEDYTMLGSDDFFYVGGSP-----STADLPGSPVSNNFMGCLKEVVYKNNDVRL 490 Query: 1208 -LEQTETLG---------VGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFR 1257 L + G V + C + + + +SFI S+ K + F+FR Sbjct: 491 ELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFI-SLPKWNAKKTGSISFDFR 549 Query: 1258 TLQPNGLLFYYASGS--------------DVFSISLDNGTV--IMDVKG--IKVQSVDKQ 1299 T +PNGL+ + D F+I + +G + ++D+ IK++++ K+ Sbjct: 550 TTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKK 609 Query: 1300 YNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSP------- 1352 NDG + V + V+ R P + +I + + Y GG P Sbjct: 610 VNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDL---DDELYLGGLPENKAGLV 666 Query: 1353 ------ISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLH 1406 + + GCI + + +D+ + T V S Sbjct: 667 FPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSC-------------- 712 Query: 1407 KKGKNLSKPKASQN-KKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQY 1465 K +KP S K G +D W+ +L S Y Sbjct: 713 --SKETAKPCLSNPCKNNGMCRDG--WNRYVCDCSGTG-------YLGRSCEREATVLSY 761 Query: 1466 GGTANSRQEFE---HLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRL 1522 G+ + + H + + S+R R++ ++G++ + ++ D + L L GR+ Sbjct: 762 DGSMFMKIQLPVVMHTEAE-----DVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRV 816 Query: 1523 VYMFNVGHKKLKIRSQE---------KYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLP 1573 N+ ++ S + ND WH V +R S +L +D + + + Sbjct: 817 KLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMA 876 Query: 1574 PTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPC 1633 + I G + + + +V N F G L +L NG + + + C Sbjct: 877 GDHTRLEFHN-IETGIITERRYLSSVPSN----FIGHLQSLTFNGMAYIDLCKNGDIDYC 931 Query: 1634 -------FEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNG 1686 F + F T+ YV L + + F+ + S G +++ Sbjct: 932 ELNARFGFRNIIADPVTFKTKSSYVAL-ATLQAYTSMHLFFQFKTTSLDGLILYNSGDGN 990 Query: 1687 EYLNVHMKNGQV--IVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRD-SNVVQLDVDSE 1743 +++ V + G + + + NG S + L D +WH + + RD SN+ + +D++ Sbjct: 991 DFIVVELVKGYLHYVFDLGNGANLIKGS--SNKPLNDNQWHNVMISRDTSNLHTVKIDTK 1048 Query: 1744 VNHVVGPLNPKPIDHREPVFVGGVPESLL--TPRLAPSKP-FTGCIRHFVIDGH-PVSFS 1799 + + + +D + +++GGV + P+L +K F GC+ ++G P S Sbjct: 1049 ITTQI-TAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLIS 1107 Query: 1800 KAALVSGAV 1808 A +G + Sbjct: 1108 DALFCNGQI 1116 Score = 56.2 bits (134), Expect = 3e-07 Identities = 87/371 (23%), Positives = 143/371 (38%), Gaps = 48/371 (12%) Query: 886 EYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIER-------VGKHGKV 938 +Y+ LA+KN + V NLG+ E ++ + VK+ R +G H V Sbjct: 362 DYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIG-HAMV 420 Query: 939 FLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGC 998 S++ + + G D ++L D FYVGG PS LP S F+GC Sbjct: 421 NKLHCSVTISVDGILTTTGYTQEDYTMLG---SDDFFYVGGSPSTADLPGSPVSNNFMGC 477 Query: 999 LELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITR 1058 L+ N+ + L + DP + +AF A+ D + Sbjct: 478 LKEVVYKNNDVRLELSRLAKQGDPKMKI---HGVVAFKCENVAT--LDPITFETPESFIS 532 Query: 1059 RGKFG--QVTRFDIEVRTPADNGLILL---------------MVNGSMFFRLEMRNGYLH 1101 K+ + + RT NGLIL M+ FF +EM +G+L+ Sbjct: 533 LPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVD-FFAIEMLDGHLY 591 Query: 1102 VFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKI 1161 + D G G + ++ LKK +ND +++ + I V R + E + Sbjct: 592 LLLDMG--SGTIKIKALLKK--VNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEIL 647 Query: 1162 PFTD-IYIGGAPPE----ILQSRALRAHLPLDINFRGCMKG--FQFQKKDF-NLLEQTET 1213 D +Y+GG P + + A L+ + GC++ Q KD + E T Sbjct: 648 DLDDELYLGGLPENKAGLVFPTEVWTA--LLNYGYVGCIRDLFIDGQSKDIRQMAEVQST 705 Query: 1214 LGVGYGCPEDS 1224 GV C +++ Sbjct: 706 AGVKPSCSKET 716 Score = 50.1 bits (118), Expect = 2e-05 Identities = 35/144 (24%), Positives = 68/144 (47%), Gaps = 7/144 (4%) Query: 1485 KSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAH-GRLVYMFNV-GHKKLKIRSQEKYN 1542 +S+ S +L+TRS+ G++ Y D+ DF+ L L GRL F++ + + + N Sbjct: 51 ESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVN 110 Query: 1543 DGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAP--GKAVKNVQ 1600 DG WH V R+ + L ID + + + +++GG+ P A + Sbjct: 111 DGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLT 170 Query: 1601 INSIYS---FSGCLSNLQLNGASI 1621 + S+ F G + ++++N + + Sbjct: 171 LASVREREPFKGWIRDVRVNSSQV 194 Score = 47.8 bits (112), Expect = 1e-04 Identities = 145/764 (18%), Positives = 275/764 (35%), Gaps = 143/764 (18%) Query: 884 KKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVP 943 K ++ + + + +L + ++G+ ++I K V+ Y V +R G+ G + + Sbjct: 577 KVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYH--VDFQRDGRSGTISVNTL 634 Query: 944 SLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSN-------FKLPTSLNLPGFV 996 TA G+ +LDLD E Y+GG+P N ++ T+L G+V Sbjct: 635 RTPYTAP----------GESEILDLDDE---LYLGGLPENKAGLVFPTEVWTALLNYGYV 681 Query: 997 GCLE---LATLNNDVISLYNFKHIYNMDPSTSVPCARDKLA-------FTQSRAASYFFD 1046 GC+ + + D+ + + + PS S A+ L+ + Y D Sbjct: 682 GCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCD 741 Query: 1047 --GSGY---AVVRDITRRGKFGQV------------TRFDIEVRTPADNGLILLMVNGSM 1089 G+GY + R+ T G + D+ +R + +LM S Sbjct: 742 CSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSR 801 Query: 1090 ----FFRLEMRNGYLHVFYDF-------GFSGGPVHLEDTLKKAQINDAKYHEISIIYHN 1138 RLE+ G + + + S GP E +ND ++H + ++ Sbjct: 802 DSADTLRLELDAGRVKLTVNLDCIRINCNSSKGP---ETLFAGYNLNDNEWHTVRVV-RR 857 Query: 1139 DKKMILVVDRRHVKS--MDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMK 1196 K + L VD + + M + ++ F +I G I+ R + +P NF G ++ Sbjct: 858 GKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETG-----IITERRYLSSVPS--NFIGHLQ 910 Query: 1197 GFQF---------QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFF 1247 F + D + E G ++I+ F +S ++ + + Sbjct: 911 SLTFNGMAYIDLCKNGDIDYCELNARFGFR------NIIADPVTFKTKSSYVALATLQAY 964 Query: 1248 DGFEGGFNFRTLQPNGLLFYYAS-GSDVFSISLDNGTV--IMDV---KGIKVQSVDKQYN 1301 F F+T +GL+ Y + G+D + L G + + D+ + S +K N Sbjct: 965 TSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLN 1024 Query: 1302 DGLSHFVISSVSPTRYELIVDKSRV------GSKNPTKGKIEQTQASEKKFYFGGSPISA 1355 D H V+ S + + +++ G++N K+ Y + Sbjct: 1025 DNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVH 1084 Query: 1356 QYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKP 1415 F GC+++ VD + + D + S LF + + P Sbjct: 1085 AKEGFQGCLAS-----VDLNGRLPD----------------LISDALFCNGQIERGCEGP 1123 Query: 1416 KASQNKKGGKSKDA--PSWDPVALKL-------PERNTPRNSHCHLSNSPRAIEHAYQYG 1466 + + ++ WD + P N P ++ + Y++ Sbjct: 1124 STTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQI---TYKWP 1180 Query: 1467 GTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMF 1526 + L F + ++ +R SS G+ D++ L + G++ F Sbjct: 1181 PNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGL---------GDYLELHIHQGKIGVKF 1231 Query: 1527 NVGHKKLKIR-SQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLE 1569 NVG + I S NDG +H V F R + L +D V+E Sbjct: 1232 NVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIE 1275 Score = 47.4 bits (111), Expect = 1e-04 Identities = 71/390 (18%), Positives = 140/390 (35%), Gaps = 74/390 (18%) Query: 1484 AKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQE---K 1540 + + ++ +T +G++ + + D++ L L +G + + N+G + + K Sbjct: 337 SSDEITLSFKTLQRNGLMLHTG--KSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGK 394 Query: 1541 YNDGLWHDVIFIRE---------------RSSGRLVIDGLRVLEESLPPTEATWKIKGP- 1584 +ND WHDV R S + +DG+ + T+ + + G Sbjct: 395 FNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILT---TTGYTQEDYTMLGSD 451 Query: 1585 --IYLGGVA-----PGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFS-------- 1629 Y+GG PG V N +F GCL + + + Sbjct: 452 DFFYVGGSPSTADLPGSPVSN-------NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMK 504 Query: 1630 -----VTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHS- 1683 C F T ++ L + +N I+F+ R +G ++ H Sbjct: 505 IHGVVAFKCENVATLDPITFETPESFISLPK-WNAKKTGSISFDFRTTEPNGLILFSHGK 563 Query: 1684 ------------VNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIR 1731 + ++ + M +G + + ++ G K+ + DG W+ + R Sbjct: 564 PRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKK-VNDGEWYHVDFQR 622 Query: 1732 DSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPES---LLTP----RLAPSKPFTG 1784 D + V++ P + +D + +++GG+PE+ L+ P + + G Sbjct: 623 DGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVG 682 Query: 1785 CIRHFVIDGHPVSFSKAALVSGAVSIN-SC 1813 CIR IDG + A V + SC Sbjct: 683 CIRDLFIDGQSKDIRQMAEVQSTAGVKPSC 712 Score = 35.8 bits (81), Expect = 0.39 Identities = 37/142 (26%), Positives = 61/142 (42%), Gaps = 21/142 (14%) Query: 1060 GKFGQVTRF-----------DIEVRTPADNGLILLMVNGSMFFRLEM---RNGYLHVFYD 1105 G GQ TRF +++T + GL+L + LE+ R G L + + Sbjct: 35 GAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFS 94 Query: 1106 FGFSGGPVHLEDTLKKAQINDAKYHEISII--YHNDKKMILVVDRRHVKSMDNEKMKIPF 1163 F P L L +ND +H + I + N I V+ + V+ + F Sbjct: 95 I-FCAEPATL---LADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVF 150 Query: 1164 TDIYIGGAPPEILQSRALRAHL 1185 + +++GG PPE L++ AL+ L Sbjct: 151 SGLFVGGLPPE-LRAAALKLTL 171 >gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens] Length = 1477 Score = 87.4 bits (215), Expect = 1e-16 Identities = 162/843 (19%), Positives = 311/843 (36%), Gaps = 131/843 (15%) Query: 1045 FDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFY 1104 F GS Y D+++ + +T NGL+L + + L ++NG + + Sbjct: 286 FKGSEYFCY-DLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVI 344 Query: 1105 DFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKIPFT 1164 + G +E + ND +H++ + N ++ + S+D +T Sbjct: 345 NLGSGAFEALVEPV--NGKFNDNAWHDVKVT-RNLRQHSGIGHAMVTISVDGILTTTGYT 401 Query: 1165 D-----------IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNL-LEQTE 1212 Y+GG+P S A P+ NF GC+K ++ D L L + Sbjct: 402 QEDYTMLGSDDFFYVGGSP-----STADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLA 456 Query: 1213 TLG---------VGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQPNG 1263 G V + C + + + +SFI S+ K + F+FRT +PNG Sbjct: 457 KQGDPKMKIHGVVAFKCENVATLDPITFETPESFI-SLPKWNAKKTGSISFDFRTTEPNG 515 Query: 1264 LLFYYASGS--------------DVFSISLDNGTV--IMDVKG--IKVQSVDKQYNDGLS 1305 L+ + D F+I + +G + ++D+ IK++++ K+ NDG Sbjct: 516 LILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEW 575 Query: 1306 HFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSP------------- 1352 + V + V+ R P + +I + + Y GG P Sbjct: 576 YHVDFQRDGRSGTISVNTLRTPYTAPGESEILDL---DDELYLGGLPENKAGLVFPTEVW 632 Query: 1353 ISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNL 1412 + + GCI + + +D+ + T V S K Sbjct: 633 TALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSC----------------SKET 676 Query: 1413 SKPKASQN-KKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANS 1471 +KP S K G +D W+ +L S Y G+ Sbjct: 677 AKPCLSNPCKNNGMCRDG--WNRYVCDCSGTG-------YLGRSCEREATVLSYDGSMFM 727 Query: 1472 RQEFE---HLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNV 1528 + + H + + S+R R++ ++G++ + ++ D + L L GR+ N+ Sbjct: 728 KIQLPVVMHTEAE-----DVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNL 782 Query: 1529 GHKKLKIRSQE---------KYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATW 1579 ++ S + ND WH V +R S +L +D + + + Sbjct: 783 DCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRL 842 Query: 1580 KIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPC------ 1633 + I G + + + +V N F G L +L NG + + + C Sbjct: 843 EFHN-IETGIITERRYLSSVPSN----FIGHLQSLTFNGMAYIDLCKNGDIDYCELNARF 897 Query: 1634 -FEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVH 1692 F + F T+ YV L + + F+ + S G +++ +++ V Sbjct: 898 GFRNIIADPVTFKTKSSYVAL-ATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVE 956 Query: 1693 MKNGQV--IVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRD-SNVVQLDVDSEVNHVVG 1749 + G + + + NG S + L D +WH + + RD SN+ + +D+++ + Sbjct: 957 LVKGYLHYVFDLGNGANLIKGS--SNKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQI- 1013 Query: 1750 PLNPKPIDHREPVFVGGVPESLL--TPRLAPSKP-FTGCIRHFVIDGH-PVSFSKAALVS 1805 + +D + +++GGV + P+L +K F GC+ ++G P S A + Sbjct: 1014 TAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCN 1073 Query: 1806 GAV 1808 G + Sbjct: 1074 GQI 1076 Score = 58.2 bits (139), Expect = 7e-08 Identities = 88/371 (23%), Positives = 144/371 (38%), Gaps = 55/371 (14%) Query: 886 EYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIER-------VGKHGKV 938 +Y+ LA+KN + V NLG+ E ++ + VK+ R +G H V Sbjct: 329 DYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIG-HAMV 387 Query: 939 FLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGC 998 ++V + +T G D ++L D FYVGG PS LP S F+GC Sbjct: 388 TISVDGILTTT-------GYTQEDYTMLG---SDDFFYVGGSPSTADLPGSPVSNNFMGC 437 Query: 999 LELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITR 1058 L+ N+ + L + DP + +AF A+ D + Sbjct: 438 LKEVVYKNNDVRLELSRLAKQGDPKMKI---HGVVAFKCENVAT--LDPITFETPESFIS 492 Query: 1059 RGKFG--QVTRFDIEVRTPADNGLILL---------------MVNGSMFFRLEMRNGYLH 1101 K+ + + RT NGLIL M+ FF +EM +G+L+ Sbjct: 493 LPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVD-FFAIEMLDGHLY 551 Query: 1102 VFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKI 1161 + D G G + ++ LKK +ND +++ + I V R + E + Sbjct: 552 LLLDMG--SGTIKIKALLKK--VNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEIL 607 Query: 1162 PFTD-IYIGGAPPE----ILQSRALRAHLPLDINFRGCMKG--FQFQKKDF-NLLEQTET 1213 D +Y+GG P + + A L+ + GC++ Q KD + E T Sbjct: 608 DLDDELYLGGLPENKAGLVFPTEVWTA--LLNYGYVGCIRDLFIDGQSKDIRQMAEVQST 665 Query: 1214 LGVGYGCPEDS 1224 GV C +++ Sbjct: 666 AGVKPSCSKET 676 Score = 53.1 bits (126), Expect = 2e-06 Identities = 157/817 (19%), Positives = 293/817 (35%), Gaps = 155/817 (18%) Query: 884 KKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVP 943 K ++ + + + +L + ++G+ ++I K V+ Y V +R G+ G + + Sbjct: 537 KVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYH--VDFQRDGRSGTISVNTL 594 Query: 944 SLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSN-------FKLPTSLNLPGFV 996 TA G+ +LDLD E Y+GG+P N ++ T+L G+V Sbjct: 595 RTPYTAP----------GESEILDLDDE---LYLGGLPENKAGLVFPTEVWTALLNYGYV 641 Query: 997 GCLE---LATLNNDVISLYNFKHIYNMDPSTSVPCARDKLA-------FTQSRAASYFFD 1046 GC+ + + D+ + + + PS S A+ L+ + Y D Sbjct: 642 GCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCD 701 Query: 1047 --GSGY---AVVRDITRRGKFGQV------------TRFDIEVRTPADNGLILLMVNGSM 1089 G+GY + R+ T G + D+ +R + +LM S Sbjct: 702 CSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSR 761 Query: 1090 ----FFRLEMRNGYLHVFYDF-------GFSGGPVHLEDTLKKAQINDAKYHEISIIYHN 1138 RLE+ G + + + S GP E +ND ++H + ++ Sbjct: 762 DSADTLRLELDAGRVKLTVNLDCIRINCNSSKGP---ETLFAGYNLNDNEWHTVRVV-RR 817 Query: 1139 DKKMILVVDRRHVKS--MDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMK 1196 K + L VD + + M + ++ F +I G I+ R + +P NF G ++ Sbjct: 818 GKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETG-----IITERRYLSSVPS--NFIGHLQ 870 Query: 1197 GFQF---------QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFF 1247 F + D + E G ++I+ F +S ++ + + Sbjct: 871 SLTFNGMAYIDLCKNGDIDYCELNARFGFR------NIIADPVTFKTKSSYVALATLQAY 924 Query: 1248 DGFEGGFNFRTLQPNGLLFYYAS-GSDVFSISLDNGTV--IMDV---KGIKVQSVDKQYN 1301 F F+T +GL+ Y + G+D + L G + + D+ + S +K N Sbjct: 925 TSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLN 984 Query: 1302 DGLSHFVISSVSPTRYELIVDKSRV------GSKNPTKGKIEQTQASEKKFYFGGSPISA 1355 D H V+ S + + +++ G++N K+ Y + Sbjct: 985 DNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVH 1044 Query: 1356 QYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKP 1415 F GC+++ VD + + D + S LF + + P Sbjct: 1045 AKEGFQGCLAS-----VDLNGRLPD----------------LISDALFCNGQIERGCEGP 1083 Query: 1416 KASQNKKGGKSKDA--PSWDPVALKL-------PERNTPRNSHCHLSNSPRAIEHAYQYG 1466 + + ++ WD + P N P ++ + Y++ Sbjct: 1084 STTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQI---TYKWP 1140 Query: 1467 GTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMF 1526 + L F + ++ +R SS G+ D++ L + G++ F Sbjct: 1141 PNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGL---------GDYLELHIHQGKIGVKF 1191 Query: 1527 NVGHKKLKIR-SQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEAT-WKIKGP 1584 NVG + I S NDG +H V F R + L +D V+E + T + + Sbjct: 1192 NVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQAT 1251 Query: 1585 IYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASI 1621 I +GG G+ F G LS L NG + Sbjct: 1252 IIIGGKEQGQ-----------PFQGQLSGLYYNGLKV 1277 Score = 50.1 bits (118), Expect = 2e-05 Identities = 35/144 (24%), Positives = 68/144 (47%), Gaps = 7/144 (4%) Query: 1485 KSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAH-GRLVYMFNV-GHKKLKIRSQEKYN 1542 +S+ S +L+TRS+ G++ Y D+ DF+ L L GRL F++ + + + N Sbjct: 51 ESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVN 110 Query: 1543 DGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAP--GKAVKNVQ 1600 DG WH V R+ + L ID + + + +++GG+ P A + Sbjct: 111 DGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLT 170 Query: 1601 INSIYS---FSGCLSNLQLNGASI 1621 + S+ F G + ++++N + + Sbjct: 171 LASVREREPFKGWIRDVRVNSSQV 194 Score = 49.7 bits (117), Expect = 3e-05 Identities = 72/383 (18%), Positives = 142/383 (37%), Gaps = 67/383 (17%) Query: 1484 AKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQE---K 1540 + + ++ +T +G++ + + D++ L L +G + + N+G + + K Sbjct: 304 SSDEITLSFKTLQRNGLMLHTG--KSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGK 361 Query: 1541 YNDGLWHDVIFIRE--RSSG------RLVIDGLRVLEESLPPTEATWKIKGP---IYLGG 1589 +ND WHDV R + SG + +DG+ + T+ + + G Y+GG Sbjct: 362 FNDNAWHDVKVTRNLRQHSGIGHAMVTISVDGILT---TTGYTQEDYTMLGSDDFFYVGG 418 Query: 1590 VA-----PGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFS-------------VT 1631 PG V N +F GCL + + + Sbjct: 419 SPSTADLPGSPVSN-------NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAF 471 Query: 1632 PCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHS-------- 1683 C F T ++ L + +N I+F+ R +G ++ H Sbjct: 472 KCENVATLDPITFETPESFISLPK-WNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDA 530 Query: 1684 -----VNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQL 1738 + ++ + M +G + + ++ G K+ + DG W+ + RD + Sbjct: 531 KHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKK-VNDGEWYHVDFQRDGRSGTI 589 Query: 1739 DVDSEVNHVVGPLNPKPIDHREPVFVGGVPES---LLTP----RLAPSKPFTGCIRHFVI 1791 V++ P + +D + +++GG+PE+ L+ P + + GCIR I Sbjct: 590 SVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFI 649 Query: 1792 DGHPVSFSKAALVSGAVSIN-SC 1813 DG + A V + SC Sbjct: 650 DGQSKDIRQMAEVQSTAGVKPSC 672 Score = 35.8 bits (81), Expect = 0.39 Identities = 37/142 (26%), Positives = 61/142 (42%), Gaps = 21/142 (14%) Query: 1060 GKFGQVTRF-----------DIEVRTPADNGLILLMVNGSMFFRLEM---RNGYLHVFYD 1105 G GQ TRF +++T + GL+L + LE+ R G L + + Sbjct: 35 GAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFS 94 Query: 1106 FGFSGGPVHLEDTLKKAQINDAKYHEISII--YHNDKKMILVVDRRHVKSMDNEKMKIPF 1163 F P L L +ND +H + I + N I V+ + V+ + F Sbjct: 95 I-FCAEPATL---LADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVF 150 Query: 1164 TDIYIGGAPPEILQSRALRAHL 1185 + +++GG PPE L++ AL+ L Sbjct: 151 SGLFVGGLPPE-LRAAALKLTL 171 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.133 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 67,919,651 Number of Sequences: 37866 Number of extensions: 3237775 Number of successful extensions: 13867 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 123 Number of HSP's successfully gapped in prelim test: 674 Number of HSP's that attempted gapping in prelim test: 9629 Number of HSP's gapped (non-prelim): 2897 length of query: 1816 length of database: 18,247,518 effective HSP length: 117 effective length of query: 1699 effective length of database: 13,817,196 effective search space: 23475416004 effective search space used: 23475416004 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.