Guide to the Human Genome
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Search of human proteins with 157419126

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo
sapiens]
         (1816 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]     3655   0.0  
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]     3655   0.0  
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]     3648   0.0  
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]          831   0.0  
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]         804   0.0  
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]         799   0.0  
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]          755   0.0  
gi|21264602 laminin alpha 5 [Homo sapiens]                            687   0.0  
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa...   421   e-117
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s...   419   e-116
gi|38788416 laminin, alpha 1 precursor [Homo sapiens]                 394   e-109
gi|167614504 laminin, beta 1 precursor [Homo sapiens]                 171   5e-42
gi|143770880 laminin, beta 4 [Homo sapiens]                           164   6e-40
gi|145309326 laminin, gamma 1 precursor [Homo sapiens]                159   3e-38
gi|119703755 laminin, beta 2 precursor [Homo sapiens]                 159   3e-38
gi|110611156 laminin, gamma 3 precursor [Homo sapiens]                145   3e-34
gi|157419130 laminin, alpha 4 isoform 3 precursor [Homo sapiens]      135   3e-31
gi|157419128 laminin, alpha 4 isoform 3 precursor [Homo sapiens]      135   3e-31
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]               132   4e-30
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]      131   7e-30
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]      129   2e-29
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]            128   6e-29
gi|219842266 usherin isoform B [Homo sapiens]                         106   2e-22
gi|93204871 netrin 4 [Homo sapiens]                                   102   3e-21
gi|62868217 laminin, beta 3 precursor [Homo sapiens]                  100   2e-20
gi|62868215 laminin, beta 3 precursor [Homo sapiens]                  100   2e-20
gi|189083719 laminin, beta 3 precursor [Homo sapiens]                 100   2e-20
gi|219842259 usherin isoform A [Homo sapiens]                          92   4e-18
gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]        87   1e-16
gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]         87   1e-16

>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
          Length = 1816

 Score = 3655 bits (9478), Expect = 0.0
 Identities = 1816/1816 (100%), Positives = 1816/1816 (100%)

Query: 1    MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
            MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
Sbjct: 1    MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60

Query: 61   PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
            PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
Sbjct: 61   PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120

Query: 121  SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
            SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
Sbjct: 121  SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180

Query: 181  GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
            GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
Sbjct: 181  GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240

Query: 241  CNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAA 300
            CNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAA
Sbjct: 241  CNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAA 300

Query: 301  HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG 360
            HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG
Sbjct: 301  HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG 360

Query: 361  QLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKML 420
            QLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKML
Sbjct: 361  QLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKML 420

Query: 421  EEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSD 480
            EEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSD
Sbjct: 421  EEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSD 480

Query: 481  LQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT 540
            LQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT
Sbjct: 481  LQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT 540

Query: 541  LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK 600
            LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK
Sbjct: 541  LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK 600

Query: 601  LHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD 660
            LHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD
Sbjct: 601  LHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD 660

Query: 661  ESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDA 720
            ESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDA
Sbjct: 661  ESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDA 720

Query: 721  QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN 780
            QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN
Sbjct: 721  QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN 780

Query: 781  LTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVH 840
            LTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVH
Sbjct: 781  LTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVH 840

Query: 841  SRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYV 900
            SRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYV
Sbjct: 841  SRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYV 900

Query: 901  YNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS 960
            YNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS
Sbjct: 901  YNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS 960

Query: 961  GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM 1020
            GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM
Sbjct: 961  GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM 1020

Query: 1021 DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL 1080
            DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL
Sbjct: 1021 DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL 1080

Query: 1081 ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDK 1140
            ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDK
Sbjct: 1081 ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDK 1140

Query: 1141 KMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQF 1200
            KMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQF
Sbjct: 1141 KMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQF 1200

Query: 1201 QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ 1260
            QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ
Sbjct: 1201 QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ 1260

Query: 1261 PNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELI 1320
            PNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELI
Sbjct: 1261 PNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELI 1320

Query: 1321 VDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVED 1380
            VDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVED
Sbjct: 1321 VDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVED 1380

Query: 1381 FQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLP 1440
            FQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLP
Sbjct: 1381 FQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLP 1440

Query: 1441 ERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGM 1500
            ERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGM
Sbjct: 1441 ERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGM 1500

Query: 1501 IFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRL 1560
            IFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRL
Sbjct: 1501 IFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRL 1560

Query: 1561 VIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGAS 1620
            VIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGAS
Sbjct: 1561 VIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGAS 1620

Query: 1621 ITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH 1680
            ITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH
Sbjct: 1621 ITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH 1680

Query: 1681 GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDV 1740
            GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDV
Sbjct: 1681 GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDV 1740

Query: 1741 DSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1800
            DSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK
Sbjct: 1741 DSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1800

Query: 1801 AALVSGAVSINSCPAA 1816
            AALVSGAVSINSCPAA
Sbjct: 1801 AALVSGAVSINSCPAA 1816


>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
          Length = 1816

 Score = 3655 bits (9478), Expect = 0.0
 Identities = 1816/1816 (100%), Positives = 1816/1816 (100%)

Query: 1    MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
            MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
Sbjct: 1    MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60

Query: 61   PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
            PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
Sbjct: 61   PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120

Query: 121  SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
            SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
Sbjct: 121  SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180

Query: 181  GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
            GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
Sbjct: 181  GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240

Query: 241  CNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAA 300
            CNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAA
Sbjct: 241  CNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAA 300

Query: 301  HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG 360
            HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG
Sbjct: 301  HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG 360

Query: 361  QLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKML 420
            QLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKML
Sbjct: 361  QLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKML 420

Query: 421  EEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSD 480
            EEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSD
Sbjct: 421  EEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSD 480

Query: 481  LQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT 540
            LQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT
Sbjct: 481  LQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT 540

Query: 541  LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK 600
            LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK
Sbjct: 541  LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK 600

Query: 601  LHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD 660
            LHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD
Sbjct: 601  LHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD 660

Query: 661  ESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDA 720
            ESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDA
Sbjct: 661  ESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDA 720

Query: 721  QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN 780
            QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN
Sbjct: 721  QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN 780

Query: 781  LTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVH 840
            LTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVH
Sbjct: 781  LTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVH 840

Query: 841  SRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYV 900
            SRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYV
Sbjct: 841  SRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYV 900

Query: 901  YNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS 960
            YNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS
Sbjct: 901  YNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS 960

Query: 961  GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM 1020
            GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM
Sbjct: 961  GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM 1020

Query: 1021 DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL 1080
            DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL
Sbjct: 1021 DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL 1080

Query: 1081 ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDK 1140
            ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDK
Sbjct: 1081 ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDK 1140

Query: 1141 KMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQF 1200
            KMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQF
Sbjct: 1141 KMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQF 1200

Query: 1201 QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ 1260
            QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ
Sbjct: 1201 QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ 1260

Query: 1261 PNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELI 1320
            PNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELI
Sbjct: 1261 PNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELI 1320

Query: 1321 VDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVED 1380
            VDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVED
Sbjct: 1321 VDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVED 1380

Query: 1381 FQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLP 1440
            FQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLP
Sbjct: 1381 FQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLP 1440

Query: 1441 ERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGM 1500
            ERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGM
Sbjct: 1441 ERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGM 1500

Query: 1501 IFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRL 1560
            IFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRL
Sbjct: 1501 IFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRL 1560

Query: 1561 VIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGAS 1620
            VIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGAS
Sbjct: 1561 VIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGAS 1620

Query: 1621 ITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH 1680
            ITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH
Sbjct: 1621 ITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH 1680

Query: 1681 GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDV 1740
            GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDV
Sbjct: 1681 GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDV 1740

Query: 1741 DSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1800
            DSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK
Sbjct: 1741 DSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1800

Query: 1801 AALVSGAVSINSCPAA 1816
            AALVSGAVSINSCPAA
Sbjct: 1801 AALVSGAVSINSCPAA 1816


>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 1823

 Score = 3648 bits (9460), Expect = 0.0
 Identities = 1816/1823 (99%), Positives = 1816/1823 (99%), Gaps = 7/1823 (0%)

Query: 1    MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
            MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
Sbjct: 1    MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60

Query: 61   PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
            PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
Sbjct: 61   PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120

Query: 121  SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
            SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
Sbjct: 121  SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180

Query: 181  GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
            GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
Sbjct: 181  GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240

Query: 241  CNCGGGPCDSVTGECLEEGFEPPTG-------CDKCVWDLTDALRLAALSIEEGKSGVLS 293
            CNCGGGPCDSVTGECLEEGFEPPTG       CDKCVWDLTDALRLAALSIEEGKSGVLS
Sbjct: 241  CNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDALRLAALSIEEGKSGVLS 300

Query: 294  VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE 353
            VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE
Sbjct: 301  VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE 360

Query: 354  NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL 413
            NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL
Sbjct: 361  NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL 420

Query: 414  VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD 473
            VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD
Sbjct: 421  VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD 480

Query: 474  YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS 533
            YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS
Sbjct: 481  YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS 540

Query: 534  LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 593
            LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE
Sbjct: 541  LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 600

Query: 594  ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT 653
            ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT
Sbjct: 601  ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT 660

Query: 654  QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ 713
            QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ
Sbjct: 661  QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ 720

Query: 714  AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS 773
            AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS
Sbjct: 721  AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS 780

Query: 774  ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG 833
            ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG
Sbjct: 781  ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG 840

Query: 834  QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK 893
            QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK
Sbjct: 841  QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK 900

Query: 894  NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF 953
            NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
Sbjct: 901  NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF 960

Query: 954  IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN 1013
            IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
Sbjct: 961  IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN 1020

Query: 1014 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR 1073
            FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
Sbjct: 1021 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR 1080

Query: 1074 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS 1133
            TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
Sbjct: 1081 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS 1140

Query: 1134 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG 1193
            IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG
Sbjct: 1141 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG 1200

Query: 1194 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG 1253
            CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG
Sbjct: 1201 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG 1260

Query: 1254 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS 1313
            FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS
Sbjct: 1261 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS 1320

Query: 1314 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD 1373
            PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD
Sbjct: 1321 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD 1380

Query: 1374 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD 1433
            RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD
Sbjct: 1381 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD 1440

Query: 1434 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR 1493
            PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR
Sbjct: 1441 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR 1500

Query: 1494 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR 1553
            TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR
Sbjct: 1501 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR 1560

Query: 1554 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN 1613
            ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN
Sbjct: 1561 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN 1620

Query: 1614 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS 1673
            LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS
Sbjct: 1621 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS 1680

Query: 1674 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS 1733
            SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS
Sbjct: 1681 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS 1740

Query: 1734 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG 1793
            NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG
Sbjct: 1741 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG 1800

Query: 1794 HPVSFSKAALVSGAVSINSCPAA 1816
            HPVSFSKAALVSGAVSINSCPAA
Sbjct: 1801 HPVSFSKAALVSGAVSINSCPAA 1823


>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
          Length = 3333

 Score =  831 bits (2147), Expect = 0.0
 Identities = 559/1815 (30%), Positives = 892/1815 (49%), Gaps = 155/1815 (8%)

Query: 40   SAVGRQDPPETSEPRVALG----RLPPA-----AEKCNAGFFHT----LSGECVPCDCNG 86
            S VG ++  +T   R+AL       PPA      + C+ G++       +G CVPC+CNG
Sbjct: 1632 SEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNG 1691

Query: 87   NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESC 146
            +SN+C DGSG CV+CQ NT GEHCE+C +GY G+++ G+   C+ CPC  PH  +FA  C
Sbjct: 1692 HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS---CRACPC--PHTNSFATGC 1746

Query: 147  YRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVT 206
                G VRC C   Y G  CERCAPGY+GNP   G +C+ C C+ N         C  +T
Sbjct: 1747 VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLT 1802

Query: 207  GQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGC 266
            G C N                                   P DS   E  ++       C
Sbjct: 1803 GDCIN---------------------------------QEPKDSSPAEECDD-------C 1822

Query: 267  DKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYA 326
            D CV  L + L      +   KS +  +S+ A     +  +      L+ +L    +  +
Sbjct: 1823 DSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAIS 1882

Query: 327  LRKIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRD 386
                +I   E  +  L  + E L EK    SRK Q +        N+ ++  + A ++  
Sbjct: 1883 NHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN-------NNVNRATQSAKELDV 1935

Query: 387  KIQEINNKMLYY--------GEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDE 438
            KI+ +   +           GE + +   + S +   AQ+M+ E+R+R      + L + 
Sbjct: 1936 KIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRN---FGKHLREA 1992

Query: 439  EAD--EAYELLSQAESWQRLH-NETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDA 495
            EAD  E+  LL++  +WQ+ H  E   L   + + L++Y AKLSDL+  L +A    + A
Sbjct: 1993 EADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQA 2052

Query: 496  EDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIY 555
              +N+         ++Q + +          L+T+  SL    + L  ++   K    + 
Sbjct: 2053 NGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLA 2112

Query: 556  AEIDGAKSELQVKLSNLSNLS--HDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKA 613
            A ++ A+ EL  K+  LS  +    LV+EA  HA+ LQ+ A +L     ++  + LV+ A
Sbjct: 2113 ASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCA 2172

Query: 614  LDASNVYENIVNYVSEANETAEFALNTTDRIYDAV--SGIDTQIIYHKDESENLLNQARE 671
            +DA+  YENI+N +  A + A  A + ++     V    +  +       S+ LLN+A+ 
Sbjct: 2173 VDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKM 2232

Query: 672  LQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLIT 731
             Q K +     A+ +  + +     +K  + T L+     L   +RGD    +  ++ + 
Sbjct: 2233 TQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMV 2292

Query: 732  EEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQ 791
             +AN  T EV     P+  ++           +  +  A+  A ++V  LT  +P L  +
Sbjct: 2293 RKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRK 2352

Query: 792  LRTVEQK-RPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKA 850
            + ++ Q+  P  N+S ++ RIRELI Q R  ASK+ V M F+G+S VEV     ++DLK 
Sbjct: 2353 IESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKG 2412

Query: 851  FTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEI 910
            +TSLSL+++ P  R E   T + F++YLG+K+A ++Y+G+A+ +  L  VYNLG ++ E+
Sbjct: 2413 YTSLSLFLQRPNSR-ENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAEL 2471

Query: 911  PLDSKPVSS--WPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDL 968
             +D     S    A    VK +R+ +  ++  T  + SS  E   +   +    ++LL+L
Sbjct: 2472 QVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNL 2531

Query: 969  DPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPC 1028
            DPE+ VFYVGG P +FKLP+ L+ P + GC+EL  LN +V+SLYNFK  +N++ +   PC
Sbjct: 2532 DPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPC 2591

Query: 1029 ARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGS 1088
             R K       +   +F+G+GYA V           +  F   ++T  D GL+    NG 
Sbjct: 2592 RRRK-----EESDKNYFEGTGYARV----PTQPHAPIPTFGQTIQTTVDRGLLFFAENGD 2642

Query: 1089 MFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQ-----INDAKYHEISI-IYHNDKKM 1142
             F  L + +G L V Y          L   L K +     IN+ + H I I I    K+M
Sbjct: 2643 RFISLNIEDGKLMVRY---------KLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRM 2693

Query: 1143 ILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQK 1202
             + VD ++   +D E     F+  Y+GG P  I +   +         FRGCMK     K
Sbjct: 2694 WINVDVQNT-IIDGE--VFDFSTYYLGGIPIAIRERFNISTPA-----FRGCMKNL---K 2742

Query: 1203 KDFNLLEQTETLGVGYGCPEDSLISRRAYFN-GQSFIASIQKISFFDGFEGGFNFRTLQP 1261
            K   ++   +T+GV   C ED  + R A F+ G     +   +   D  +  F F+T QP
Sbjct: 2743 KTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQP 2802

Query: 1262 NGLLFYYASGSDVFSISLDNGTVIMDV--KGIKVQSVDKQYNDGLSHFVISSVSPTRYEL 1319
            +G+L  + + +    ++L++G + +     G  +    + Y DGL H+V      +   L
Sbjct: 2803 SGILLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRL 2862

Query: 1320 IVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVE 1379
            ++D   + +      +++   +S +    GGS       NF GCISN +  R+    EV 
Sbjct: 2863 LIDDQLLRNSK----RLKHISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEVL 2911

Query: 1380 DFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKL 1439
            D    + K   SL  C +   P  +L K     +K K  +  +    +D P   P ++K+
Sbjct: 2912 DLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKV 2969

Query: 1440 PERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHG 1499
             +        C      +A   A Q+G    S   F+  +     +SQF++ ++T SS G
Sbjct: 2970 WQ------DACSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRG 3023

Query: 1500 MIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGR 1559
            ++F+     +N FM L+L+ GRLV+      KKL+I+S+EK NDG WH V+F  +   GR
Sbjct: 3024 LVFHTG--TKNSFMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGR 3081

Query: 1560 LVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGA 1619
            LV+DGLR  E SL P  +T  I+ P+YLG    GK  K++  N   SF GCL N QL+  
Sbjct: 3082 LVVDGLRAREGSL-PGNSTISIRAPVYLGSPPSGKP-KSLPTN---SFVGCLKNFQLDSK 3136

Query: 1620 SITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLV 1679
             + + S +F V+ C  GP+E G YFS EGG+VVL  S  +G +F++ F +RPRS +G L+
Sbjct: 3137 PLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILI 3196

Query: 1680 HGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLD 1739
            H  S  G++L V+++ G+V   +++G    STSVTPKQSLCDG+WH + V    +++ L+
Sbjct: 3197 HIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLE 3256

Query: 1740 VDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFS 1799
            +D++ ++  G +   P   +EP+ +GG P +L T R+   K F GC+R+  ++  PV  +
Sbjct: 3257 LDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVT 3316

Query: 1800 KAALVSGAVSINSCP 1814
            +A  V G VS+N CP
Sbjct: 3317 EALEVQGPVSLNGCP 3331



 Score =  107 bits (268), Expect = 8e-23
 Identities = 73/237 (30%), Positives = 99/237 (41%), Gaps = 58/237 (24%)

Query: 76  SGECVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGY 117
           S EC  C+C+G+++ C                    G G C++CQ NT G +CE+C  GY
Sbjct: 350 SHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGY 409

Query: 118 I---GDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
               G  +  AP  C PC C   H    A+ C  + G+ RC C  N+ G NCE+CA GYY
Sbjct: 410 YRPYGVPV-DAPDGCIPCSCDPEH----ADGC--EQGSGRCHCKPNFHGDNCEKCAIGYY 462

Query: 175 GNPLL----------------IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTG 218
             P                  +    K CDC+      ++ E CD   G+C  C     G
Sbjct: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLE---GVLPEICD-AHGRCL-CRPGVEG 517

Query: 219 FKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGCDKCV 270
            +C+ C  G+Y        C  C C        PC SVTG+C          CD+C+
Sbjct: 518 PRCDTCRSGFYS----FPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCL 570



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 74/246 (30%), Positives = 100/246 (40%), Gaps = 66/246 (26%)

Query: 74  TLSGECVPCDCNGNSNECLDGSG---YCVHCQRNTTGEHCEKCLDGYIGDSIRGA----P 126
           ++ G+CV   CNG++  C   +    +   CQ +T GE C++C  GY     R A     
Sbjct: 294 SIGGQCV---CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQS 350

Query: 127 QFCQPCPCPLPHLANFAESCY-----------------RKNGAVRCICNENYAGPNCERC 169
             C+ C C        A +CY                    G V   C  N AG NCE+C
Sbjct: 351 HECEACNC-----HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQC 405

Query: 170 APGY---YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226
           A GY   YG P+     C  C C    DP    + C++ +G+C +C  N  G  CE+CA 
Sbjct: 406 AKGYYRPYGVPVDAPDGCIPCSC----DPEHA-DGCEQGSGRC-HCKPNFHGDNCEKCAI 459

Query: 227 GYY-----------------GDARIAKNCAVCNC---GGGP--CDSVTGECL-EEGFEPP 263
           GYY                  +  +A +   C+C   G  P  CD+  G CL   G E P
Sbjct: 460 GYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA-HGRCLCRPGVEGP 518

Query: 264 TGCDKC 269
             CD C
Sbjct: 519 R-CDTC 523



 Score = 71.2 bits (173), Expect = 8e-12
 Identities = 70/266 (26%), Positives = 96/266 (36%), Gaps = 30/266 (11%)

Query: 18   SAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSG 77
            ++A S  A     A P +   + A G    PE  +       +     +C  G  H    
Sbjct: 1250 NSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATG--HYGFP 1307

Query: 78   ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKC-LDGYIGDSIRGAPQFCQPCPCPL 136
             C PC C      C + +G C  C   T    CE C    +    + G    C+ C C  
Sbjct: 1308 RCKPCSCGRRL--CEEMTGQC-RCPPRTVRPQCEVCETHSFSFHPMAG----CEGCNCSR 1360

Query: 137  PHLANFA-ESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCS-GNSD 194
                  A   C R +G  +C C     G  C+RCA G+Y  P      C  C+C+   ++
Sbjct: 1361 RGTIEAAMPECDRDSG--QCRCKPRITGRQCDRCASGFYRFP-----ECVPCNCNRDGTE 1413

Query: 195  PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG-YYGDARIAKNCAVCNCGGGPCDSVTG 253
            P +    CD  TG C  C  N  G +C  C  G ++ D    K C  C C G     V  
Sbjct: 1414 PGV----CDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKGCTSCFCFG-----VNN 1463

Query: 254  ECLEEGFEPPTGCDKCVWDLTDALRL 279
            +C           D   W L  A R+
Sbjct: 1464 QCHSSHKRRTKFVDMLGWHLETADRV 1489



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 57/210 (27%), Positives = 73/210 (34%), Gaps = 59/210 (28%)

Query: 105  TTGEHCEKCLDGYIGDSIRGA-PQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAG 163
            T    C+      +    +GA P  C P     PH       C  + G  +C C  N  G
Sbjct: 1243 TASRFCKNSARSLVAFYHKGALPCECHPTGATGPH-------CSPEGG--QCPCQPNVIG 1293

Query: 164  PNCERCAPGYYG----NPLLIG-----------------------------------STC 184
              C RCA G+YG     P   G                                   + C
Sbjct: 1294 RQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGC 1353

Query: 185  KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244
            + C+CS          +CD  +GQCR C    TG +C+RCA G+Y        C  CNC 
Sbjct: 1354 EGCNCSRRGTIEAAMPECDRDSGQCR-CKPRITGRQCDRCASGFYR----FPECVPCNCN 1408

Query: 245  -----GGPCDSVTGECLEEGFEPPTGCDKC 269
                  G CD  TG CL +     T C+ C
Sbjct: 1409 RDGTEPGVCDPGTGACLCKENVEGTECNVC 1438



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 52/210 (24%), Positives = 77/210 (36%), Gaps = 24/210 (11%)

Query: 62  PAAEKCNAGFFHTLSGECVPCDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDG-YIG 119
           P  + C +GF+     +   C   G+    C   +G C  C+   TG+ C++CL G Y  
Sbjct: 518 PRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDF 576

Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
              +G+   C P      +L               C C  +  GP C RC   Y+     
Sbjct: 577 PHCQGSSSACDPAGTINSNLGY-------------CQCKLHVEGPTCSRCKLLYWNLDKE 623

Query: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCA 239
             S C +C C      +   E C +  G C +C  +  G  C+ C  GY+      +   
Sbjct: 624 NPSGCSECKCHKAGTVSGTGE-CRQGDGDC-HCKSHVGGDSCDTCEDGYFA----LEKSN 677

Query: 240 VCNCGGGPCDSVTGECLEEGFEPPTGCDKC 269
              C G  CD   G  L      P+G  +C
Sbjct: 678 YFGCQGCQCD--IGGALSSMCSGPSGVCQC 705



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 13/102 (12%)

Query: 79  CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF-CQPC 132
           C  C C+       + EC  G G C HC+ +  G+ C+ C DGY   ++  +  F CQ C
Sbjct: 628 CSECKCHKAGTVSGTGECRQGDGDC-HCKSHVGGDSCDTCEDGYF--ALEKSNYFGCQGC 684

Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
            C +      +  C   +G   C C E+  G  C+R    YY
Sbjct: 685 QCDIG--GALSSMCSGPSGV--CQCREHVVGKVCQRPENNYY 722


>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
          Length = 3277

 Score =  804 bits (2076), Expect = 0.0
 Identities = 547/1805 (30%), Positives = 870/1805 (48%), Gaps = 191/1805 (10%)

Query: 40   SAVGRQDPPETSEPRVALG----RLPPA-----AEKCNAGFFHT----LSGECVPCDCNG 86
            S VG ++  +T   R+AL       PPA      + C+ G++       +G CVPC+CNG
Sbjct: 1632 SEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNG 1691

Query: 87   NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESC 146
            +SN+C DGSG CV+CQ NT GEHCE+C +GY G+++ G+   C+ CPC  PH  +FA  C
Sbjct: 1692 HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS---CRACPC--PHTNSFATGC 1746

Query: 147  YRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVT 206
                G VRC C   Y G  CERCAPGY+GNP   G +C+ C C+ N         C  +T
Sbjct: 1747 VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLT 1802

Query: 207  GQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGC 266
            G C N                                   P DS   E  ++       C
Sbjct: 1803 GDCIN---------------------------------QEPKDSSPAEECDD-------C 1822

Query: 267  DKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYA 326
            D CV  L + L      +   KS +  +S+ A     +  +      L+ +L    +  +
Sbjct: 1823 DSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAIS 1882

Query: 327  LRKIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRD 386
                +I   E  +  L  + E L EK    SRK Q +     + +N A+Q          
Sbjct: 1883 NHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN----NNVNRATQ---------- 1928

Query: 387  KIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYEL 446
                              S KE+  K+   + ++  +                      +
Sbjct: 1929 ------------------SAKELDVKI---KNVIRNV---------------------HM 1946

Query: 447  LSQAESWQRLH-NETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAAR 505
            L++  +WQ+ H  E   L   + + L++Y AKLSDL+  L +A    + A  +N+     
Sbjct: 1947 LNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERA 2006

Query: 506  QRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSEL 565
                ++Q + +          L+T+  SL    + L  ++   K    + A ++ A+ EL
Sbjct: 2007 LGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQEL 2066

Query: 566  QVKLSNLSNLS--HDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENI 623
              K+  LS  +    LV+EA  HA+ LQ+ A +L     ++  + LV+ A+DA+  YENI
Sbjct: 2067 SDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENI 2126

Query: 624  VNYVSEANETAEFALNTTDRIYDAV--SGIDTQIIYHKDESENLLNQARELQAKAESSSD 681
            +N +  A + A  A + ++     V    +  +       S+ LLN+A+  Q K +    
Sbjct: 2127 LNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVS 2186

Query: 682  EAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEV 741
             A+ +  + +     +K  + T L+     L   +RGD    +  ++ +  +AN  T EV
Sbjct: 2187 PALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEV 2246

Query: 742  QQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQK-RP 800
                 P+  ++           +  +  A+  A ++V  LT  +P L  ++ ++ Q+  P
Sbjct: 2247 LDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLP 2306

Query: 801  ASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKP 860
              N+S ++ RIRELI Q R  ASK+ V M F+G+S VEV     ++DLK +TSLSL+++ 
Sbjct: 2307 LGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQR 2366

Query: 861  PVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSS- 919
            P  R E   T + F++YLG+K+A ++Y+G+A+ +  L  VYNLG ++ E+ +D     S 
Sbjct: 2367 PNSR-ENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSE 2425

Query: 920  -WPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVG 978
               A    VK +R+ +  ++  T  + SS  E   +   +    ++LL+LDPE+ VFYVG
Sbjct: 2426 TKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVG 2485

Query: 979  GVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQS 1038
            G P +FKLP+ L+ P + GC+EL  LN +V+SLYNFK  +N++ +   PC R K      
Sbjct: 2486 GYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRK-----E 2540

Query: 1039 RAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNG 1098
             +   +F+G+GYA V           +  F   ++T  D GL+    NG  F  L + +G
Sbjct: 2541 ESDKNYFEGTGYARV----PTQPHAPIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDG 2596

Query: 1099 YLHVFYDFGFSGGPVHLEDTLKKAQ-----INDAKYHEISI-IYHNDKKMILVVDRRHVK 1152
             L V Y          L   L K +     IN+ + H I I I    K+M + VD ++  
Sbjct: 2597 KLMVRY---------KLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNT- 2646

Query: 1153 SMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTE 1212
             +D E     F+  Y+GG P  I +   +         FRGCMK     KK   ++   +
Sbjct: 2647 IIDGE--VFDFSTYYLGGIPIAIRERFNISTPA-----FRGCMKNL---KKTSGVVRLND 2696

Query: 1213 TLGVGYGCPEDSLISRRAYFN-GQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASG 1271
            T+GV   C ED  + R A F+ G     +   +   D  +  F F+T QP+G+L  + + 
Sbjct: 2697 TVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTW 2756

Query: 1272 SDVFSISLDNGTVIMDV--KGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSK 1329
            +    ++L++G + +     G  +    + Y DGL H+V      +   L++D   + + 
Sbjct: 2757 TRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNS 2816

Query: 1330 NPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVH 1389
                 +++   +S +    GGS       NF GCISN +  R+    EV D    + K  
Sbjct: 2817 K----RLKHISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEVLDLTSNSLKRD 2865

Query: 1390 TSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSH 1449
             SL  C +   P  +L K     +K K  +  +    +D P   P ++K+ +        
Sbjct: 2866 VSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKVWQ------DA 2917

Query: 1450 CHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEE 1509
            C      +A   A Q+G    S   F+  +     +SQF++ ++T SS G++F+     +
Sbjct: 2918 CSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTG--TK 2975

Query: 1510 NDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLE 1569
            N FM L+L+ GRLV+      KKL+I+S+EK NDG WH V+F  +   GRLV+DGLR  E
Sbjct: 2976 NSFMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRARE 3035

Query: 1570 ESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFS 1629
             SL P  +T  I+ P+YLG    GK  K++  N   SF GCL N QL+   + + S +F 
Sbjct: 3036 GSL-PGNSTISIRAPVYLGSPPSGKP-KSLPTN---SFVGCLKNFQLDSKPLYTPSSSFG 3090

Query: 1630 VTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYL 1689
            V+ C  GP+E G YFS EGG+VVL  S  +G +F++ F +RPRS +G L+H  S  G++L
Sbjct: 3091 VSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHL 3150

Query: 1690 NVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVG 1749
             V+++ G+V   +++G    STSVTPKQSLCDG+WH + V    +++ L++D++ ++  G
Sbjct: 3151 CVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAG 3210

Query: 1750 PLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVS 1809
             +   P   +EP+ +GG P +L T R+   K F GC+R+  ++  PV  ++A  V G VS
Sbjct: 3211 QIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVS 3270

Query: 1810 INSCP 1814
            +N CP
Sbjct: 3271 LNGCP 3275



 Score =  107 bits (268), Expect = 8e-23
 Identities = 73/237 (30%), Positives = 99/237 (41%), Gaps = 58/237 (24%)

Query: 76  SGECVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGY 117
           S EC  C+C+G+++ C                    G G C++CQ NT G +CE+C  GY
Sbjct: 350 SHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGY 409

Query: 118 I---GDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
               G  +  AP  C PC C   H    A+ C  + G+ RC C  N+ G NCE+CA GYY
Sbjct: 410 YRPYGVPV-DAPDGCIPCSCDPEH----ADGC--EQGSGRCHCKPNFHGDNCEKCAIGYY 462

Query: 175 GNPLL----------------IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTG 218
             P                  +    K CDC+      ++ E CD   G+C  C     G
Sbjct: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLE---GVLPEICD-AHGRCL-CRPGVEG 517

Query: 219 FKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGCDKCV 270
            +C+ C  G+Y        C  C C        PC SVTG+C          CD+C+
Sbjct: 518 PRCDTCRSGFYS----FPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCL 570



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 74/246 (30%), Positives = 100/246 (40%), Gaps = 66/246 (26%)

Query: 74  TLSGECVPCDCNGNSNECLDGSG---YCVHCQRNTTGEHCEKCLDGYIGDSIRGA----P 126
           ++ G+CV   CNG++  C   +    +   CQ +T GE C++C  GY     R A     
Sbjct: 294 SIGGQCV---CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQS 350

Query: 127 QFCQPCPCPLPHLANFAESCY-----------------RKNGAVRCICNENYAGPNCERC 169
             C+ C C        A +CY                    G V   C  N AG NCE+C
Sbjct: 351 HECEACNC-----HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQC 405

Query: 170 APGY---YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226
           A GY   YG P+     C  C C    DP    + C++ +G+C +C  N  G  CE+CA 
Sbjct: 406 AKGYYRPYGVPVDAPDGCIPCSC----DPEHA-DGCEQGSGRC-HCKPNFHGDNCEKCAI 459

Query: 227 GYY-----------------GDARIAKNCAVCNC---GGGP--CDSVTGECL-EEGFEPP 263
           GYY                  +  +A +   C+C   G  P  CD+  G CL   G E P
Sbjct: 460 GYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA-HGRCLCRPGVEGP 518

Query: 264 TGCDKC 269
             CD C
Sbjct: 519 R-CDTC 523



 Score = 71.2 bits (173), Expect = 8e-12
 Identities = 70/266 (26%), Positives = 96/266 (36%), Gaps = 30/266 (11%)

Query: 18   SAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSG 77
            ++A S  A     A P +   + A G    PE  +       +     +C  G  H    
Sbjct: 1250 NSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATG--HYGFP 1307

Query: 78   ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKC-LDGYIGDSIRGAPQFCQPCPCPL 136
             C PC C      C + +G C  C   T    CE C    +    + G    C+ C C  
Sbjct: 1308 RCKPCSCGRRL--CEEMTGQC-RCPPRTVRPQCEVCETHSFSFHPMAG----CEGCNCSR 1360

Query: 137  PHLANFA-ESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCS-GNSD 194
                  A   C R +G  +C C     G  C+RCA G+Y  P      C  C+C+   ++
Sbjct: 1361 RGTIEAAMPECDRDSG--QCRCKPRITGRQCDRCASGFYRFP-----ECVPCNCNRDGTE 1413

Query: 195  PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG-YYGDARIAKNCAVCNCGGGPCDSVTG 253
            P +    CD  TG C  C  N  G +C  C  G ++ D    K C  C C G     V  
Sbjct: 1414 PGV----CDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKGCTSCFCFG-----VNN 1463

Query: 254  ECLEEGFEPPTGCDKCVWDLTDALRL 279
            +C           D   W L  A R+
Sbjct: 1464 QCHSSHKRRTKFVDMLGWHLETADRV 1489



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 57/210 (27%), Positives = 73/210 (34%), Gaps = 59/210 (28%)

Query: 105  TTGEHCEKCLDGYIGDSIRGA-PQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAG 163
            T    C+      +    +GA P  C P     PH       C  + G  +C C  N  G
Sbjct: 1243 TASRFCKNSARSLVAFYHKGALPCECHPTGATGPH-------CSPEGG--QCPCQPNVIG 1293

Query: 164  PNCERCAPGYYG----NPLLIG-----------------------------------STC 184
              C RCA G+YG     P   G                                   + C
Sbjct: 1294 RQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGC 1353

Query: 185  KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244
            + C+CS          +CD  +GQCR C    TG +C+RCA G+Y        C  CNC 
Sbjct: 1354 EGCNCSRRGTIEAAMPECDRDSGQCR-CKPRITGRQCDRCASGFYR----FPECVPCNCN 1408

Query: 245  -----GGPCDSVTGECLEEGFEPPTGCDKC 269
                  G CD  TG CL +     T C+ C
Sbjct: 1409 RDGTEPGVCDPGTGACLCKENVEGTECNVC 1438



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 52/210 (24%), Positives = 77/210 (36%), Gaps = 24/210 (11%)

Query: 62  PAAEKCNAGFFHTLSGECVPCDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDG-YIG 119
           P  + C +GF+     +   C   G+    C   +G C  C+   TG+ C++CL G Y  
Sbjct: 518 PRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDF 576

Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
              +G+   C P      +L               C C  +  GP C RC   Y+     
Sbjct: 577 PHCQGSSSACDPAGTINSNLGY-------------CQCKLHVEGPTCSRCKLLYWNLDKE 623

Query: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCA 239
             S C +C C      +   E C +  G C +C  +  G  C+ C  GY+      +   
Sbjct: 624 NPSGCSECKCHKAGTVSGTGE-CRQGDGDC-HCKSHVGGDSCDTCEDGYFA----LEKSN 677

Query: 240 VCNCGGGPCDSVTGECLEEGFEPPTGCDKC 269
              C G  CD   G  L      P+G  +C
Sbjct: 678 YFGCQGCQCD--IGGALSSMCSGPSGVCQC 705



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 13/102 (12%)

Query: 79  CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF-CQPC 132
           C  C C+       + EC  G G C HC+ +  G+ C+ C DGY   ++  +  F CQ C
Sbjct: 628 CSECKCHKAGTVSGTGECRQGDGDC-HCKSHVGGDSCDTCEDGYF--ALEKSNYFGCQGC 684

Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
            C +      +  C   +G   C C E+  G  C+R    YY
Sbjct: 685 QCDIG--GALSSMCSGPSGV--CQCREHVVGKVCQRPENNYY 722


>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
          Length = 1668

 Score =  799 bits (2063), Expect = 0.0
 Identities = 541/1789 (30%), Positives = 864/1789 (48%), Gaps = 183/1789 (10%)

Query: 47   PPETSEPRVALGRLPPAAEKCNAGFFHT----LSGECVPCDCNGNSNECLDGSGYCVHCQ 102
            PP  S+ + +     P+ + C+ G++       +G CVPC+CNG+SN+C DGSG CV+CQ
Sbjct: 40   PPGQSQLQASYVEFRPS-QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQ 98

Query: 103  RNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYA 162
             NT GEHCE+C +GY G+++ G+   C+ CPC  PH  +FA  C    G VRC C   Y 
Sbjct: 99   HNTAGEHCERCQEGYYGNAVHGS---CRACPC--PHTNSFATGCVVNGGDVRCSCKAGYT 153

Query: 163  GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCE 222
            G  CERCAPGY+GNP   G +C+ C C+ N         C  +TG C N           
Sbjct: 154  GTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLTGDCIN----------- 198

Query: 223  RCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAAL 282
                                    P DS   E  ++       CD CV  L + L     
Sbjct: 199  ----------------------QEPKDSSPAEECDD-------CDSCVMTLLNDLATMGE 229

Query: 283  SIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSL 342
             +   KS +  +S+ A     +  +      L+ +L    +  +    +I   E  +  L
Sbjct: 230  QLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDL 289

Query: 343  LSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEH 402
              + E L EK    SRK Q +     + +N A+Q                          
Sbjct: 290  NQEFETLQEKAQVNSRKAQTLN----NNVNRATQ-------------------------- 319

Query: 403  ELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLH-NETR 461
              S KE+  K+   + ++  +                      +L++  +WQ+ H  E  
Sbjct: 320  --SAKELDVKI---KNVIRNV---------------------HMLNRIRTWQKTHQGENN 353

Query: 462  TLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQME 521
             L   + + L++Y AKLSDL+  L +A    + A  +N+         ++Q + +     
Sbjct: 354  GLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQS 413

Query: 522  VVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLS--HDL 579
                 L+T+  SL    + L  ++   K    + A ++ A+ EL  K+  LS  +    L
Sbjct: 414  DFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSL 473

Query: 580  VQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALN 639
            V+EA  HA+ LQ+ A +L     ++  + LV+ A+DA+  YENI+N +  A + A  A +
Sbjct: 474  VEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAAS 533

Query: 640  TTDRIYDAV--SGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALAR 697
             ++     V    +  +       S+ LLN+A+  Q K +     A+ +  + +     +
Sbjct: 534  ASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQ 593

Query: 698  KSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQ 757
            K  + T L+     L   +RGD    +  ++ +  +AN  T EV     P+  ++     
Sbjct: 594  KEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKD 653

Query: 758  NLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQK-RPASNVSASIQRIRELIA 816
                  +  +  A+  A ++V  LT  +P L  ++ ++ Q+  P  N+S ++ RIRELI 
Sbjct: 654  TYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQ 713

Query: 817  QTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFIL 876
            Q R  ASK+ V M F+G+S VEV     ++DLK +TSLSL+++ P  R E   T + F++
Sbjct: 714  QARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSR-ENGGTENMFVM 772

Query: 877  YLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSS--WPAYFSIVKIERVGK 934
            YLG+K+A ++Y+G+A+ +  L  VYNLG ++ E+ +D     S    A    VK +R+ +
Sbjct: 773  YLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQ 832

Query: 935  HGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPG 994
              ++  T  + SS  E   +   +    ++LL+LDPE+ VFYVGG P +FKLP+ L+ P 
Sbjct: 833  FARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPP 892

Query: 995  FVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVR 1054
            + GC+EL  LN +V+SLYNFK  +N++ +   PC R K       +   +F+G+GYA V 
Sbjct: 893  YKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRK-----EESDKNYFEGTGYARV- 946

Query: 1055 DITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVH 1114
                      +  F   ++T  D GL+    NG  F  L + +G L V Y          
Sbjct: 947  ---PTQPHAPIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVRY---------K 994

Query: 1115 LEDTLKKAQ-----INDAKYHEISI-IYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYI 1168
            L   L K +     IN+ + H I I I    K+M + VD ++   +D E     F+  Y+
Sbjct: 995  LNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNT-IIDGE--VFDFSTYYL 1051

Query: 1169 GGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISR 1228
            GG P  I +   +         FRGCMK     KK   ++   +T+GV   C ED  + R
Sbjct: 1052 GGIPIAIRERFNISTPA-----FRGCMKNL---KKTSGVVRLNDTVGVTKKCSEDWKLVR 1103

Query: 1229 RAYFN-GQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMD 1287
             A F+ G     +   +   D  +  F F+T QP+G+L  + + +    ++L++G + + 
Sbjct: 1104 SASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTLEDGYIELS 1163

Query: 1288 V--KGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKK 1345
                G  +    + Y DGL H+V      +   L++D   + +      +++   +S + 
Sbjct: 1164 TSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSK----RLKHISSSRQS 1219

Query: 1346 FYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLL 1405
               GGS       NF GCISN +  R+    EV D    + K   SL  C +   P  +L
Sbjct: 1220 LRLGGS-------NFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLML 1272

Query: 1406 HKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQY 1465
             K     +K K  +  +    +D P   P ++K+ +        C      +A   A Q+
Sbjct: 1273 LKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKVWQ------DACSPLPKTQANHGALQF 1324

Query: 1466 GGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYM 1525
            G    S   F+  +     +SQF++ ++T SS G++F+     +N FM L+L+ GRLV+ 
Sbjct: 1325 GDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTG--TKNSFMALYLSKGRLVFA 1382

Query: 1526 FNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPI 1585
                 KKL+I+S+EK NDG WH V+F  +   GRLV+DGLR  E SL P  +T  I+ P+
Sbjct: 1383 LGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSL-PGNSTISIRAPV 1441

Query: 1586 YLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFS 1645
            YLG    GK  K++  N   SF GCL N QL+   + + S +F V+ C  GP+E G YFS
Sbjct: 1442 YLGSPPSGKP-KSLPTN---SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFS 1497

Query: 1646 TEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNG 1705
             EGG+VVL  S  +G +F++ F +RPRS +G L+H  S  G++L V+++ G+V   +++G
Sbjct: 1498 EEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSG 1557

Query: 1706 IRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVG 1765
                STSVTPKQSLCDG+WH + V    +++ L++D++ ++  G +   P   +EP+ +G
Sbjct: 1558 AGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLG 1617

Query: 1766 GVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSCP 1814
            G P +L T R+   K F GC+R+  ++  PV  ++A  V G VS+N CP
Sbjct: 1618 GAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCP 1666


>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
          Length = 1724

 Score =  755 bits (1949), Expect = 0.0
 Identities = 538/1801 (29%), Positives = 870/1801 (48%), Gaps = 125/1801 (6%)

Query: 60   LPPAAEK--CNAGF---FHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCL 114
            +PPA  +  C+ G+   F    G+C+           L   G              + C 
Sbjct: 1    MPPAVRRSACSMGWLWIFGAALGQCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCS 60

Query: 115  DGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGY 173
             GY  D        C PC C        +  C  ++G+  C+ C  N AG +CERC  GY
Sbjct: 61   PGYYRDHKGLYTGRCVPCNCN-----GHSNQC--QDGSGICVNCQHNTAGEHCERCQEGY 113

Query: 174  YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCR-NCLRNTTGFKCERCAPGYYGDA 232
            YGN   +  +C+ C C      N     C    G  R +C    TG +CERCAPGY+G+ 
Sbjct: 114  YGNA--VHGSCRACPCPHT---NSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 168

Query: 233  -RIAKNCAVCNCGG----GPCDSVTGECLEEG------FEPPTGCDKCVWDLTDALRLAA 281
             +   +C  C+C      G C  +TG+C+ +        E    CD CV  L + L    
Sbjct: 169  QKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMG 228

Query: 282  LSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKS 341
              +   KS +  +S+ A     +  +      L+ +L    +  +    +I   E  +  
Sbjct: 229  EQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTD 288

Query: 342  LLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYY--- 398
            L  + E L EK    SRK Q +        N+ ++  + A ++  KI+ +   +      
Sbjct: 289  LNQEFETLQEKAQVNSRKAQTLN-------NNVNRATQSAKELDVKIKNVIRNVHILLKQ 341

Query: 399  -----GEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEAD--EAYELLSQAE 451
                 GE + +   + S +   AQ+M+ E+R+R      + L + EAD  E+  LL++  
Sbjct: 342  ISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRN---FGKHLREAEADKRESQLLLNRIR 398

Query: 452  SWQRLHN-ETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHE 510
            +WQ+ H  E   L   + + L++Y AKLSDL+  L +A    + A  +N+         +
Sbjct: 399  TWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQ 458

Query: 511  KQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLS 570
            +Q + +          L+T+  SL    + L  ++   K    + A ++ A+ EL  K+ 
Sbjct: 459  RQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVR 518

Query: 571  NLSNLSH--DLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVS 628
             LS  +    LV+EA  HA+ LQ+ A +L     ++  + LV+ A+DA+  YENI+N + 
Sbjct: 519  ELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIK 578

Query: 629  EANETAEFALNTTDRIYDAV--SGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVAD 686
             A + A  A + ++     V    +  +       S+ LLN+A+  Q K +     A+ +
Sbjct: 579  AAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNN 638

Query: 687  TSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATA 746
              + +     +K  + T L+     L   +RGD    +  ++ +  +AN  T EV     
Sbjct: 639  LQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLN 698

Query: 747  PMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKR-PASNVS 805
            P+  ++           +  +  A+  A ++V  LT  +P L  ++ ++ Q+  P  N+S
Sbjct: 699  PIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNIS 758

Query: 806  ASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRP 865
             ++ RIRELI Q R  ASK+ V M F+G+S VEV     ++DLK +TSLSL+++ P  R 
Sbjct: 759  DNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSR- 817

Query: 866  ELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWP--AY 923
            E   T + F++YLG+K+A ++Y+G+A+ +  L  VYNLG ++ E+ +D     S    A 
Sbjct: 818  ENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAV 877

Query: 924  FSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSN 983
               VK +R+ +  ++  T  + SS  E   +   +    ++LL+LDPE+ VFYVGG P +
Sbjct: 878  MDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPD 937

Query: 984  FKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASY 1043
            FKLP+ L+ P + GC+EL  LN +V+SLYNFK  +N++ +   PC R K       +   
Sbjct: 938  FKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRK-----EESDKN 992

Query: 1044 FFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVF 1103
            +F+G+GYA V           +  F   ++T  D GL+    NG  F  L + +G L V 
Sbjct: 993  YFEGTGYARVPTQPH----APIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVR 1048

Query: 1104 YDFGFSGGPVHLEDTLKKAQ-----INDAKYHEISI-IYHNDKKMILVVDRRHVKSMDNE 1157
            Y          L   L K +     IN+ + H I I I    K+M + VD ++   +D E
Sbjct: 1049 YK---------LNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNT-IIDGE 1098

Query: 1158 KMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVG 1217
                 F+  Y+GG P  I +   +         FRGCMK     KK   ++   +T+GV 
Sbjct: 1099 VFD--FSTYYLGGIPIAIRERFNISTPA-----FRGCMKNL---KKTSGVVRLNDTVGVT 1148

Query: 1218 YGCPEDSLISRRAYFN--GQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDVF 1275
              C ED  + R A F+  GQ     +  +   D  +  F F+T QP+G+L  + + +   
Sbjct: 1149 KKCSEDWKLVRSASFSRGGQLSFTDLG-LPPTDHLQASFGFQTFQPSGILLDHQTWTRNL 1207

Query: 1276 SISLDNGTVIMDVK--GIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTK 1333
             ++L++G + +     G  +    + Y DGL H+V      +   L++D   + +     
Sbjct: 1208 QVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSK--- 1264

Query: 1334 GKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLY 1393
             +++   +S +    GGS       NF GCISN +  R+    EV D    + K   SL 
Sbjct: 1265 -RLKHISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLG 1316

Query: 1394 ECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHLS 1453
             C +   P  +L K     +K K  +  +    +D P   P ++K+ +        C   
Sbjct: 1317 GCSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKVWQ------DACSPL 1368

Query: 1454 NSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFM 1513
               +A   A Q+G    S   F+  +     +SQF++ ++T SS G++F+   +  N FM
Sbjct: 1369 PKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTK--NSFM 1426

Query: 1514 TLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLP 1573
             L+L+ GRLV+      KKL+I+S+EK NDG WH V+F  +   GRLV+DGLR  E SLP
Sbjct: 1427 ALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLP 1486

Query: 1574 PTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPC 1633
               +T  I+ P+YLG    GK  K++  NS   F GCL N QL+   + + S +F V+ C
Sbjct: 1487 GN-STISIRAPVYLGSPPSGKP-KSLPTNS---FVGCLKNFQLDSKPLYTPSSSFGVSSC 1541

Query: 1634 FEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHM 1693
              GP+E G YFS EGG+VVL  S  +G +F++ F +RPRS +G L+H  S  G++L V++
Sbjct: 1542 LGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYL 1601

Query: 1694 KNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNP 1753
            + G+V   +++G    STSVTPKQSLCDG+WH + V    +++ L++D++ ++  G +  
Sbjct: 1602 EAGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPF 1661

Query: 1754 KPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSC 1813
             P   +EP+ +GG P +L T R+   K F GC+R+  ++  PV  ++A  V G VS+N C
Sbjct: 1662 PPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGC 1721

Query: 1814 P 1814
            P
Sbjct: 1722 P 1722


>gi|21264602 laminin alpha 5 [Homo sapiens]
          Length = 3695

 Score =  687 bits (1772), Expect = 0.0
 Identities = 532/1925 (27%), Positives = 879/1925 (45%), Gaps = 241/1925 (12%)

Query: 63   AAEKCNAGFFHTLSG----ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYI 118
            + ++C  GF+  + G     CVPC C+G+S+ CL GSG CV CQ NT G HCE+C  G++
Sbjct: 1841 SCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFV 1900

Query: 119  GDSIRGAPQF-CQPCPCPLPHLAN-FAESCYRKNGAVR---------------------- 154
              S R  P   C  CPCPL   +N FAE C  + G  +                      
Sbjct: 1901 --SSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGN 1958

Query: 155  ----------CICNEN-----------------------YAGPNCERCAPGYYGNPLLIG 181
                      C C+ N                         GP CE CAPG+YGN LL G
Sbjct: 1959 PLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPG 2018

Query: 182  STCKKCDC-----------SGNS--------------------------------DPNLI 198
            + C +CDC           SG+                                  P   
Sbjct: 2019 N-CTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAE 2077

Query: 199  FEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGEC--- 255
              +C   +GQC +C   T G +C  CAPGY+G     + C  C C GG CD  TG C   
Sbjct: 2078 GSECHPQSGQC-HCRPGTMGPQCRECAPGYWGLPE--QGCRRCQCPGGRCDPHTGRCNCP 2134

Query: 256  ------------LEEGFEPPTG----------CDKCVWDLTDALRLAALSIEEGKSGVLS 293
                         +     P G          CD CV  L D L  A   +      +  
Sbjct: 2135 PGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHCVVLLLDDLERAGALLPAIHEQLRG 2194

Query: 294  VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEEL---- 349
            +++ + A   ++ +NA+I  L+++L            Q+   E    SL  D   L    
Sbjct: 2195 INASSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQDARRLGGQA 2254

Query: 350  VEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSP--K 407
            V   +QAS+   L   E+  T+ HA  L+     +   + E+ ++  + G  +  +P  +
Sbjct: 2255 VGTRDQASQL--LAGTEA--TLGHAKTLLAAIRAVDRTLSELMSQTGHLGLANASAPSGE 2310

Query: 408  EISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQA-ESWQRLHNETRTLFPV 466
            ++   L   +++L E+R+R      +   + E   A  LL++  E    L  E + L   
Sbjct: 2311 QLLRTLAEVERLLWEMRARD-LGAPQAAAEAELAAAQRLLARVQEQLSSLWEENQALATQ 2369

Query: 467  VLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMS 526
              ++L  + A L DL+EAL++A++  R+A+++N     R  +  ++++ +      +  +
Sbjct: 2370 TRDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEALQRKQELSRDNATLQAT 2429

Query: 527  LSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDL--VQEAI 584
            L  + D+L +    L  LD   +    + A +DGA++ L  ++   S     L  V+ A 
Sbjct: 2430 LHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFSPAGSKLRLVEAAE 2489

Query: 585  DHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRI 644
             HAQ L Q A  LS  +   + + L Q+A++ASN Y  I+  V  A + A  AL   D  
Sbjct: 2490 AHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQALQQADHT 2549

Query: 645  YDAVSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTR 704
            +  V              + L+++A++L A + ++ +EA+    +R+G   A     +T+
Sbjct: 2550 WATVV------------RQGLVDRAQQLLANS-TALEEAMLQEQQRLGLVWAALQGARTQ 2596

Query: 705  LSD-------------AVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANN 751
            L D             A + + A +  +  +++  ++ +  EA  T   VQ     M  N
Sbjct: 2597 LRDVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAAEAQDTATRVQSQLQAMQEN 2656

Query: 752  LTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQK---RPASNVSASI 808
            +  W    +         AV  A  +V  L + +PQLL +L  +E +     +  +SASI
Sbjct: 2657 VERWQGQYEGLRGQDLGQAVLDAGHSVSTLEKTLPQLLAKLSILENRGVHNASLALSASI 2716

Query: 809  QRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELT 868
             R+RELIAQ R  ASK++V M F+G+S V++ +   + DL A+T+L  Y++ P   P   
Sbjct: 2717 GRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYTALKFYLQGPEPEPG-Q 2775

Query: 869  ETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVK 928
             T D+F++Y+GS+ A  +YMG+++++  + +VY LG     +    + +      F+ V 
Sbjct: 2776 GTEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQLGEAGPAVLSIDEDIGE---QFAAVS 2832

Query: 929  IERVGKHGKVFLTVPSLSSTAEEKFIK--KGEF--SGDDSLLDLDPEDTVFYVGGVPSNF 984
            ++R  + G + +TV       E + I+  KG+    G + LL+L P+D VFYVGG PS F
Sbjct: 2833 LDRTLQFGHMSVTV-------ERQMIQETKGDTVAPGAEGLLNLRPDDFVFYVGGYPSTF 2885

Query: 985  KLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYF 1044
              P  L  PG+ GC+E+ TLN +V+SLYNF+  + +D +   PCAR K           +
Sbjct: 2886 TPPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDPWLTDGSY 2945

Query: 1045 FDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFY 1104
             DG+G+A    I+   +     RF+ E+R  + +G++  +   S F  L ++ G L + Y
Sbjct: 2946 LDGTGFA---RISFDSQISTTKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQEGSLVLLY 3002

Query: 1105 DFGF---SGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKI 1161
            DFG       P+     L  A    +K  ++ ++  + K++++ V+R  V S++ +    
Sbjct: 3003 DFGAGLKKAVPLQPPPPLTSA----SKAIQVFLLGGSRKRVLVRVERATVYSVEQDNDLE 3058

Query: 1162 PFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYGCP 1221
                 Y+GG PP+ L   +LR   P   + RGC+KG +   K  + L++  T GV  GC 
Sbjct: 3059 LADAYYLGGVPPDQLPP-SLRRLFPTGGSVRGCVKGIKALGKYVD-LKRLNTTGVSAGCT 3116

Query: 1222 EDSLISRRAYFNGQSFI-ASIQKISFFDG-FEGGFNFRTLQPNGLLFYYASGSDVFSISL 1279
             D L+ R   F+G  F+  ++  ++   G    GF F + Q + LL+Y AS   +  +SL
Sbjct: 3117 ADLLVGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYYRASPDGLCQVSL 3176

Query: 1280 DNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQT 1339
              G V + +   +V++    + DG  H+V    + T   L VD  ++    P +G   + 
Sbjct: 3177 QQGRVSLQLLRTEVKT-QAGFADGAPHYVAFYSNATGVWLYVD-DQLQQMKPHRGPPPEL 3234

Query: 1340 QASEK---KFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECP 1396
            Q   +   +   GG P S    NF+GCISN +  R+     V D Q+    V+ S    P
Sbjct: 3235 QPQPEGPPRLLLGGLPESGTIYNFSGCISNVFVQRLLGPQRVFDLQQNLGSVNVSTGCAP 3294

Query: 1397 IESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSP 1456
               +    L  +G   +  KAS+  +       P+  P  +  P   T R+S        
Sbjct: 3295 ALQAQTPGLGPRGLQATARKASRRSR------QPARHPACMLPPHLRTTRDS-------- 3340

Query: 1457 RAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSD-QEENDFMTL 1515
                  YQ+GG+ +S  EF  +          S+ +  RSS G++ + +  +  +  + L
Sbjct: 3341 ------YQFGGSLSSHLEFVGILARHRNWPSLSMHVLPRSSRGLLLFTARLRPGSPSLAL 3394

Query: 1516 FLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPT 1575
            FL++G  V        +L+ +S+++   G WH V    E++   LV DG R   +  P  
Sbjct: 3395 FLSNGHFVAQMEGLGTRLRAQSRQRSRPGRWHKVSVRWEKNRILLVTDGARAWSQEGPHR 3454

Query: 1576 E---ATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTP 1632
            +   A       +++GG+        + +     FSGC+  L+L+G  + + ++   VTP
Sbjct: 3455 QHQGAEHPQPHTLFVGGLPASSHSSKLPVT--VGFSGCVKRLRLHGRPLGAPTRMAGVTP 3512

Query: 1633 CFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH-GHSVNGEYLNV 1691
            C  GP+E G +F   GG + LD          +  EVRP + +G + H G +    YL +
Sbjct: 3513 CILGPLEAGLFFPGSGGVITLDLPGATLPDVGLELEVRPLAVTGLIFHLGQARTPPYLQL 3572

Query: 1692 HMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPL 1751
             +   QV+++ ++G  +FSTSVT    LCDG+WHR+ V++  NV++L+VD++ NH VGPL
Sbjct: 3573 QVTEKQVLLRADDGAGEFSTSVTRPSVLCDGQWHRLAVMKSGNVLRLEVDAQSNHTVGPL 3632

Query: 1752 NPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSIN 1811
                     P+++GG+PE +      P+  + GC+R   ++  PV+ +++  V GAV  +
Sbjct: 3633 LAAAAGAPAPLYLGGLPEPMAVQPWPPA--YCGCMRRLAVNRSPVAMTRSVEVHGAVGAS 3690

Query: 1812 SCPAA 1816
             CPAA
Sbjct: 3691 GCPAA 3695



 Score =  103 bits (256), Expect = 2e-21
 Identities = 71/231 (30%), Positives = 98/231 (42%), Gaps = 46/231 (19%)

Query: 76  SGECVPCDCNGNSNEC--------------LDGS----GYCVHCQRNTTGEHCEKCLDGY 117
           + EC  C+C G++ +C              LDG+    G C+ CQ +TTG +CE+CL G+
Sbjct: 353 ANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGF 412

Query: 118 IGDSIR--GAPQFCQPCPCPLPHLANFAE-SCYRKNGAVRCICNENYAGPNCERCAPGYY 174
                    +P  C+ C C     ++F + +C    G  RC C  N++G  C+ CA G+ 
Sbjct: 413 YRSPNHPLDSPHVCRRCNCE----SDFTDGTCEDLTG--RCYCRPNFSGERCDVCAEGFT 466

Query: 175 GNP---------------LLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGF 219
           G P               +L       CDCS            D   G+C  C  N  G 
Sbjct: 467 GFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRK-DPRVGRCL-CKPNFQGT 524

Query: 220 KCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGEC-LEEGFEPPTGCDKC 269
            CE CAPG+YG       C+        CD  TG+C    GFE  T CD+C
Sbjct: 525 HCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGAT-CDRC 574



 Score =  102 bits (254), Expect = 3e-21
 Identities = 73/244 (29%), Positives = 98/244 (40%), Gaps = 42/244 (17%)

Query: 40  SAVGRQDPPETSEPRVALGRLPPA-----AEKCNAGFFHTLSGECVPCDCNGNS---NEC 91
           SA G Q      +PRV      P       E C  GF+      C PC C+      + C
Sbjct: 497 SAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFY---GPGCQPCQCSSPGVADDRC 553

Query: 92  LDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNG 151
              +G C  C+    G  C++C  GY    +      CQ C C         E C   + 
Sbjct: 554 DPDTGQC-RCRVGFEGATCDRCAPGYFHFPL------CQLCGCS--PAGTLPEGC---DE 601

Query: 152 AVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRN 211
           A RC+C   +AGP+C+RC PGY+G P      C+ C C    DP    +      G CR 
Sbjct: 602 AGRCLCQPEFAGPHCDRCRPGYHGFP-----NCQACTC----DPRGALDQLCGAGGLCR- 651

Query: 212 CLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGC 266
           C    TG  C+ C+PG++G      +C  C+C         CD  +G+C          C
Sbjct: 652 CRPGYTGTACQECSPGFHG----FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRC 707

Query: 267 DKCV 270
           D CV
Sbjct: 708 DTCV 711



 Score =  100 bits (250), Expect = 1e-20
 Identities = 66/198 (33%), Positives = 90/198 (45%), Gaps = 33/198 (16%)

Query: 81   PCDCN---GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
            PC C+        C    G C  C  +  G  C +C  GY G      P  C+PC C   
Sbjct: 1437 PCGCHEVGATGPTCEPFGGQCP-CHAHVIGRDCSRCATGYWG-----FPN-CRPCDCG-- 1487

Query: 138  HLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNL 197
                 A  C    G  +CIC      P+C  C P  +G   L+G  C++C+CSG     L
Sbjct: 1488 -----ARLCDELTG--QCICPPRTIPPDCLLCQPQTFGCHPLVG--CEECNCSGPGIQEL 1538

Query: 198  IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC-----GGGPCDSVT 252
                CD  +GQC+ C  N TG +C+ C+PG++G  R    C  C+C       G CD +T
Sbjct: 1539 TDPTCDTDSGQCK-CRPNVTGRRCDTCSPGFHGYPR----CRPCDCHEAGTAPGVCDPLT 1593

Query: 253  GEC-LEEGFEPPTGCDKC 269
            G+C  +E  + P  CD+C
Sbjct: 1594 GQCYCKENVQGPK-CDQC 1610



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 61/211 (28%), Positives = 85/211 (40%), Gaps = 24/211 (11%)

Query: 63  AAEKCNAGFFHTLSGECVPCDCNGNSN---ECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
           A ++C+ GF    S  CVPC C+   +    C   SG C  C+   TG  C+ C+ G   
Sbjct: 660 ACQECSPGFHGFPS--CVPCHCSAEGSLHAACDPRSGQC-SCRPRVTGLRCDTCVPGAYN 716

Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
                   +C+   C    LA    +       V C+C  +  GP+C+RC PG++G    
Sbjct: 717 FP------YCEAGSCHPAGLAPVDPAL--PEAQVPCMCRAHVEGPSCDRCKPGFWGLSPS 768

Query: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNC 238
               C +C C        + E C   TGQC  C  +  G  C  C  G++G D      C
Sbjct: 769 NPEGCTRCSCDLRGTLGGVAE-CQPGTGQC-FCKPHVCGQACASCKDGFFGLDQADYFGC 826

Query: 239 AVCNCGGGPCDSVTGECLEEGFEPPTGCDKC 269
             C C         G  L +  EP TG  +C
Sbjct: 827 RSCRCD-------IGGALGQSCEPRTGVCRC 850



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 55/171 (32%), Positives = 77/171 (45%), Gaps = 23/171 (13%)

Query: 79   CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG-DSIRGAPQFCQPCPCPLP 137
            C PCDC      C + +G C+ C   T    C  C     G   + G    C+ C C  P
Sbjct: 1481 CRPCDCGARL--CDELTGQCI-CPPRTIPPDCLLCQPQTFGCHPLVG----CEECNCSGP 1533

Query: 138  HLANFAE-SCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDC-SGNSDP 195
             +    + +C   +G  +C C  N  G  C+ C+PG++G P      C+ CDC    + P
Sbjct: 1534 GIQELTDPTCDTDSG--QCKCRPNVTGRRCDTCSPGFHGYP-----RCRPCDCHEAGTAP 1586

Query: 196  NLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCGG 245
             +    CD +TGQC  C  N  G KC++C+ G +  DA   K C  C C G
Sbjct: 1587 GV----CDPLTGQCY-CKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFG 1632



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 65/250 (26%), Positives = 97/250 (38%), Gaps = 69/250 (27%)

Query: 74  TLSGECVPCDCNGNSNEC-----LDGSGYCVHCQRNTTGEHCEKCLDGYIGD----SIRG 124
           ++ G CV   C+G+++ C      D       CQ NT G  C++C  G+       +   
Sbjct: 295 SIGGRCV---CHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATAN 351

Query: 125 APQFCQPCPCPLPHLANFAESCY-----------------RKNGAVRCICNENYAGPNCE 167
           +   CQ C C        A  CY                  + G V   C  +  G NCE
Sbjct: 352 SANECQSCNC-----YGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCE 406

Query: 168 RCAPGYY---GNPLLIGSTCKKCDCSGNSDPNLIFED--CDEVTGQCRNCLRNTTGFKCE 222
           RC PG+Y    +PL     C++C+C  +      F D  C+++TG+C  C  N +G +C+
Sbjct: 407 RCLPGFYRSPNHPLDSPHVCRRCNCESD------FTDGTCEDLTGRC-YCRPNFSGERCD 459

Query: 223 RCAPGYYG------------DAR---------IAKNCAVCNCGGGPC--DSVTGECLEEG 259
            CA G+ G            D R         +  +C+     G  C  D   G CL + 
Sbjct: 460 VCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKP 519

Query: 260 FEPPTGCDKC 269
               T C+ C
Sbjct: 520 NFQGTHCELC 529



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 45/161 (27%), Positives = 66/161 (40%), Gaps = 29/161 (18%)

Query: 143 AESCYRKNGA----VRCICNENYAGPNCERCAPGYYGNP-----LLIGSTCKKCDCSGNS 193
           A++C  K+      ++C C  N  G  C+RC PG+   P         + C+ C+C G++
Sbjct: 306 ADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHA 365

Query: 194 -----DPNL-------IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN---- 237
                DP +         +   +  G C +C  +TTG  CERC PG+Y       +    
Sbjct: 366 TDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHV 425

Query: 238 CAVCNCGG----GPCDSVTGECLEEGFEPPTGCDKCVWDLT 274
           C  CNC      G C+ +TG C          CD C    T
Sbjct: 426 CRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFT 466



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 46/144 (31%), Positives = 63/144 (43%), Gaps = 22/144 (15%)

Query: 60   LPPAAEKCNAGFF--HTLSGECVPCDCNGNSNE------CLDGSGYCVHCQRNTTGEHCE 111
            +PP    C    F  H L G C  C+C+G   +      C   SG C  C+ N TG  C+
Sbjct: 1505 IPPDCLLCQPQTFGCHPLVG-CEECNCSGPGIQELTDPTCDTDSGQC-KCRPNVTGRRCD 1562

Query: 112  KCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAES-CYRKNGAVRCICNENYAGPNCERCA 170
             C  G+      G P+ C+PC C   H A  A   C    G  +C C EN  GP C++C+
Sbjct: 1563 TCSPGF-----HGYPR-CRPCDC---HEAGTAPGVCDPLTG--QCYCKENVQGPKCDQCS 1611

Query: 171  PGYYGNPLLIGSTCKKCDCSGNSD 194
             G +         C +C C G ++
Sbjct: 1612 LGTFSLDAANPKGCTRCFCFGATE 1635



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 33/92 (35%), Positives = 45/92 (48%), Gaps = 10/92 (10%)

Query: 155  CICNENYAGPNCERCAPGYYGN--PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNC 212
            C+C  +Y G +C+ CAPG+Y +   L +G  C  C C G+SD       C   +G C +C
Sbjct: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLG-RCVPCQCHGHSD------RCLPGSGVCVDC 1883

Query: 213  LRNTTGFKCERCAPGYYGDA-RIAKNCAVCNC 243
              NT G  CERC  G+       +  C  C C
Sbjct: 1884 QHNTEGAHCERCQAGFVSSRDDPSAPCVSCPC 1915



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 48/169 (28%), Positives = 69/169 (40%), Gaps = 23/169 (13%)

Query: 21  CSRAASGDDNAFPFDIEGS---SAVGRQDP--PETSEPRVALGRLP-PAAEKCNAGFFHT 74
           C     G  N FP+   GS   + +   DP  PE   P +    +  P+ ++C  GF+  
Sbjct: 707 CDTCVPGAYN-FPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGL 765

Query: 75  LSGE---CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
                  C  C C+     G   EC  G+G C  C+ +  G+ C  C DG+ G  +  A 
Sbjct: 766 SPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCF-CKPHVCGQACASCKDGFFG--LDQAD 822

Query: 127 QF-CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
            F C+ C C +       +SC  + G   C C  N  GP C   A  +Y
Sbjct: 823 YFGCRSCRCDIG--GALGQSCEPRTGV--CRCRPNTQGPTCSEPARDHY 867



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 34/122 (27%)

Query: 178  LLIGSTCKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
            L   +  + C C   G + P      C+   GQC  C  +  G  C RCA GY+G     
Sbjct: 1429 LFYNNGARPCGCHEVGATGPT-----CEPFGGQCP-CHAHVIGRDCSRCATGYWG----F 1478

Query: 236  KNCAVCNCGGGPCDSVTGECL----------------EEGFEPPTGCDKC------VWDL 273
             NC  C+CG   CD +TG+C+                  G  P  GC++C      + +L
Sbjct: 1479 PNCRPCDCGARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQEL 1538

Query: 274  TD 275
            TD
Sbjct: 1539 TD 1540


>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
            sapiens]
          Length = 3122

 Score =  421 bits (1082), Expect = e-117
 Identities = 450/1858 (24%), Positives = 778/1858 (41%), Gaps = 219/1858 (11%)

Query: 57   LGRLPPAAEKCNAGFFHTLS-----------GECVPCDCNGNSNECLDGSGYCVHCQRNT 105
            LG    + E C  GF+   S           G CVPC CNG+S+ C   +  C +CQ +T
Sbjct: 1384 LGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHT 1443

Query: 106  TGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLA-NFAESCYRKN-GAVRC-ICNENYA 162
             G+ CE+C  GY G  ++G P  CQ C CPL   + NF+ SC  +     RC  C   Y 
Sbjct: 1444 AGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYE 1502

Query: 163  GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDP-NLIFEDCDEVTGQCRNCLRNTTGFKC 221
            G  CERCAPGY G+P   G +C++C+C    DP   +   CD VTG C  C    TG KC
Sbjct: 1503 GQYCERCAPGYTGSPGNPGGSCQECEC----DPYGSLPVPCDPVTGFC-TCRPGATGRKC 1557

Query: 222  ERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAA 281
            + C    +  AR    C  C   G  C  +                     L D  RL  
Sbjct: 1558 DGCK---HWHAREGWECVFC---GDECTGLL--------------------LGDLARLEQ 1591

Query: 282  LSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKS 341
            + +    +G L      A ++ +  +      LK  LS +     L    I  AE  + +
Sbjct: 1592 MVMSINLTGPL-----PAPYKMLYGLENMTQELKHLLSPQRAPERL----IQLAEGNLNT 1642

Query: 342  LLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEE 401
            L++++ EL+ +  + +  G+   +++  T   A  L E   ++    + +N K +   E 
Sbjct: 1643 LVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNET 1702

Query: 402  HELSPKEISEKLVLAQK----MLEEIRSRQPFFTQRELVDEEADEAYELLSQAES-WQRL 456
                 +     L   QK    M++E+R R+   TQ+E+ ++E   A  LL + +  +   
Sbjct: 1703 LGTRDEAFERNLEGLQKEIDQMIKELR-RKNLETQKEIAEDELVAAEALLKKVKKLFGES 1761

Query: 457  HNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDH---EKQQ 513
              E   +   + E+L DY  K+ D  + L +A + +R+A   NR  A  Q++    EK++
Sbjct: 1762 RGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREA---NRLFAVNQKNMTALEKKK 1818

Query: 514  ERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLS 573
            E V      +  +L    D L        E++ II     I  ++     EL  K+ +LS
Sbjct: 1819 EAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLS 1878

Query: 574  NLSHD-LVQEAIDHAQDLQQEANELSRKLHS--SDMNGLVQKALDASNVYENIVNYVSEA 630
                D  + E +  A+    + N+ S  L     +   +   A  A   Y NI +Y+ EA
Sbjct: 1879 QEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFKAYSNIKDYIDEA 1938

Query: 631  NETAEFALNTTDRIYDAVSG----IDTQIIYHKDESENLLNQARELQAKAESSSDEAVAD 686
             + A+ A +         +G    +         +S  +LN+A++L    + + D  +  
Sbjct: 1939 EKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVKENEDH-LNG 1997

Query: 687  TSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATA 746
               R+  A AR   L   L+D + +L A    D   +L   +    +AN T  +V     
Sbjct: 1998 LKTRIENADARNGDLLRTLNDTLGKLSAIP-NDTAAKLQAVKDKARQANDTAKDVLAQIT 2056

Query: 747  PMANNLTNWSQNLQHFDSS-----------AYNTAVNSARDAVRNLTEVVPQLLDQLRTV 795
             +  NL    +N      S           + N  +  A   V+NL +   +L+D+L+ +
Sbjct: 2057 ELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPI 2116

Query: 796  EQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLK--AFTS 853
              K    N+  +I  I+ELI Q R  A+ I+VS+   G        RT   ++K  ++ +
Sbjct: 2117 --KELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCI-----RTYKPEIKKGSYNN 2169

Query: 854  LSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLD 913
            + + +K        T  AD  + YLGS     +++ + ++   + +++++G+    +   
Sbjct: 2170 IVVNVK--------TAVADNLLFYLGSAKF-IDFLAIEMRKGKVSFLWDVGSGVGRVEYP 2220

Query: 914  SKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDT 973
               +    +Y+  +   R G++G + +        +              ++LD+D  + 
Sbjct: 2221 DLTIDD--SYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVD-ANA 2277

Query: 974  VFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIY-NMDPSTSVPCARDK 1032
            + +VGG+    K   ++ +  F GC+     +N  I L+NF+    +    T  P   D 
Sbjct: 2278 MLFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDS 2337

Query: 1033 LAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSM--F 1090
                Q       FDG GYA+V    R   +  ++    + RT + + L++ +    +  F
Sbjct: 2338 EGTIQ-------FDGEGYALVSRPIR--WYPNISTVMFKFRTFSSSALLMYLATRDLRDF 2388

Query: 1091 FRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVD--- 1147
              +E+ +G++ V YD G SG    +   +     ND K+   ++     +  I +VD   
Sbjct: 2389 MSVELTDGHIKVSYDLG-SG----MASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDT 2443

Query: 1148 --RRHV---KSMDNEKMKIPFTD-IYIGGAPPEILQSRALRAHLPLDI-NFRGCMKGFQF 1200
                ++    S +N  + +   D IY GG P   L++ +++A   +++  + GC+K  + 
Sbjct: 2444 NQEENIATSSSGNNFGLDLKADDKIYFGGLP--TLRNLSMKARPEVNLKKYSGCLKDIEI 2501

Query: 1201 QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ 1260
             +  +N+L   + +GV  GC  +++ +    F    F+  +  +    G E   +F T  
Sbjct: 2502 SRTPYNILSSPDYVGVTKGCSLENVYT--VSFPKPGFV-ELSPVPIDVGTEINLSFSTKN 2558

Query: 1261 PNGLLFYYASGSDV-------------FSISLDNG-------TVIMDVKGIKVQSVDKQY 1300
             +G++   + G+               + I L+ G       T    ++ I ++     +
Sbjct: 2559 ESGIILLGSGGTPAPPRRKRRQTGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLF 2618

Query: 1301 NDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQ---- 1356
            +DG  H V    +   + + VD++R   +N T   +EQ     KK + GG+P   Q    
Sbjct: 2619 HDGREHSVHVERTRGIFTVQVDENRRYMQNLT---VEQ-PIEVKKLFVGGAPPEFQPSPL 2674

Query: 1357 --YANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSK 1414
                 F GCI N     V       DF R     +  +  C                 + 
Sbjct: 2675 RNIPPFEGCIWNLVINSVPM-----DFARPVSFKNADIGRC-----------------AH 2712

Query: 1415 PKASQNKKGGKSKD-APSWDPVALKLPERNTPRNSH--CHLSNSPRAIEHAYQYGGTANS 1471
             K  +++ G    +     +PV        TP  +H  C   + P  +  + Q+G + NS
Sbjct: 2713 QKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALLIGSKQFGLSRNS 2772

Query: 1472 RQEFEHLKGDFGAKSQFSIRL--RTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVG 1529
                     D   K++ +I L  RT +  G++FY++     DF T+ L +G   + +++G
Sbjct: 2773 HIAIAF--DDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLG 2830

Query: 1530 HKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEA-TWKIKGPIYLG 1588
                      K NDG WH +  +R +  G L +DG      ++ P +A    + G +Y+G
Sbjct: 2831 SGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDG--ASNRTISPKKADILDVVGMLYVG 2888

Query: 1589 GVAPGKAVKNVQINSIYSFSGCLSNLQL--NGASITSASQTFSVTPCFEGPMETGTYFST 1646
            G+      + +     YS  GC+ NL +    A +   + +F V  CF    + GTYF  
Sbjct: 2889 GLPINYTTRRIG-PVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFAN-AQRGTYFDG 2946

Query: 1647 EGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGI 1706
              G+      F +GL   + FE R  +++G L+   S   + + + M + +++  V+NG 
Sbjct: 2947 T-GFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFHVDNGA 3005

Query: 1707 RDFST--SVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNP--KPIDHREPV 1762
              F+          LCDG+WH++T  +  + ++L VD        P NP     D  +PV
Sbjct: 3006 GRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSP-NPASTSADTNDPV 3064

Query: 1763 FVGGVPESLLTPRLAPSKPFTGCIRHFVI---DGHP--VSFSKAALVSGAVSINSCPA 1815
            FVGG P+ L    L  S PF GCIR   +    G P  V+F+KA  + G   + SCPA
Sbjct: 3065 FVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPV-SCPA 3121



 Score =  175 bits (444), Expect = 3e-43
 Identities = 88/216 (40%), Positives = 117/216 (54%), Gaps = 12/216 (5%)

Query: 62  PAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
           P   + N   F    G C PC C G++  C D +G C++C+ +T G +C+KCL G+ G+ 
Sbjct: 740 PRHRRVNGTIF---GGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEP 796

Query: 122 IRGAPQFCQPCPCPLPHLA-NFAESCY--RKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
            +G  + CQPC CPL   + NF+ +C+  R  G +   C   Y GP CERCA GY+G P 
Sbjct: 797 TKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS 856

Query: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC 238
           + G +C+ C C+ N D + I   CD ++G C  C   TTG  CE CA GY+GDA  AKNC
Sbjct: 857 VPGGSCQPCQCNDNLDFS-IPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNC 915

Query: 239 AVCNCGGG-----PCDSVTGECLEEGFEPPTGCDKC 269
             C C  G      C S TG+C          CDKC
Sbjct: 916 QPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKC 951



 Score =  132 bits (332), Expect = 3e-30
 Identities = 79/223 (35%), Positives = 106/223 (47%), Gaps = 25/223 (11%)

Query: 57   LGRLPPAAEKCNAGFFHTLS---GECVPCDCNGNSNECLDGS-----GYCVHCQRNTTGE 108
            +G   P  E+C  G+F   S   G C PC CN N +  + GS     G C+ C+  TTG 
Sbjct: 837  VGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGR 896

Query: 109  HCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCER 168
            +CE C DGY GD++    + CQPC C      +F+E C+ + G  +C C  N  G  C++
Sbjct: 897  YCELCADGYFGDAVDA--KNCQPCRCNAG--GSFSEVCHSQTG--QCECRANVQGQRCDK 950

Query: 169  CAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGY 228
            C  G +G  L     C  C+C+     +    DC+E +GQC  C    TG KC+RCA GY
Sbjct: 951  CKAGTFG--LQSARGCVPCNCNSFGSKSF---DCEE-SGQCW-CQPGVTGKKCDRCAHGY 1003

Query: 229  YGDARIAKNCAVCNCG--GGPCDSVTGECLEEGFEPPTGCDKC 269
            +        C  C C   G  CD  TG C+         C KC
Sbjct: 1004 FNFQE--GGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKC 1044



 Score =  110 bits (275), Expect = 1e-23
 Identities = 74/199 (37%), Positives = 98/199 (49%), Gaps = 30/199 (15%)

Query: 65   EKCNAGFFHTLSGE-CVPCDCNGNSNECLD--GSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
            +KC AG F   S   CVPC+CN   ++  D   SG C  CQ   TG+ C++C  GY    
Sbjct: 949  DKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQC-WCQPGVTGKKCDRCAHGYFNFQ 1007

Query: 122  IRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIG 181
              G    C  C C   HL N   +C  K G  RCIC  N  G  C +CAP  +G+ +  G
Sbjct: 1008 EGG----CTACECS--HLGN---NCDPKTG--RCICPPNTIGEKCSKCAPNTWGHSITTG 1056

Query: 182  STCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVC 241
              CK C+CS  +  +L F+ C+  TGQC NC    +G KC  C+ G++   R    C +C
Sbjct: 1057 --CKACNCS--TVGSLDFQ-CNVNTGQC-NCHPKFSGAKCTECSRGHWNYPR----CNLC 1106

Query: 242  NC-----GGGPCDSVTGEC 255
            +C         CDS T +C
Sbjct: 1107 DCFLPGTDATTCDSETKKC 1125



 Score =  102 bits (254), Expect = 3e-21
 Identities = 63/200 (31%), Positives = 87/200 (43%), Gaps = 26/200 (13%)

Query: 65   EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
            ++C  G+F+   G C  C+C+   N C   +G C+ C  NT GE C KC     G SI  
Sbjct: 997  DRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCI-CPPNTIGEKCSKCAPNTWGHSITT 1055

Query: 125  APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
                C+ C C      +F   C    G  +C C+  ++G  C  C+ G++  P      C
Sbjct: 1056 G---CKACNCSTVGSLDF--QCNVNTG--QCNCHPKFSGAKCTECSRGHWNYP-----RC 1103

Query: 185  KKCDC------SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKN 237
              CDC      +   D       C + TGQC  C  N  G  C+RC PG +G DA+    
Sbjct: 1104 NLCDCFLPGTDATTCDSETKKCSCSDQTGQC-TCKVNVEGIHCDRCRPGKFGLDAKNPLG 1162

Query: 238  CAVCNCGGGPCDSVTGECLE 257
            C+ C C G      T +C E
Sbjct: 1163 CSSCYCFG-----TTTQCSE 1177



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 76/261 (29%), Positives = 105/261 (40%), Gaps = 48/261 (18%)

Query: 69  AGFFHTLSGECVPCDCNGNSNECLD------------------GSGYCVHCQRNTTGEHC 110
           AG F T + EC  C+C+G + EC                    G G C++C +NT G +C
Sbjct: 332 AGTFLTKT-ECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINC 390

Query: 111 EKCLDGYIGDSIRGAPQFCQPC-PCPLPHLANFAESCYRKNGAVR-------CICNENYA 162
           E C DG+       +P + +PC PC    + +  E C +     R       C C   + 
Sbjct: 391 ETCTDGFFRPK-GVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFG 449

Query: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCE 222
           G +C+RCA GY G P      CK C+CSG    N      D   G C  C  N  G  C 
Sbjct: 450 GVSCDRCARGYTGYP-----DCKACNCSGLGSKNE-----DPCFGPC-ICKENVEGGDCS 498

Query: 223 RCAPGYYG-DARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTD---ALR 278
           RC  G++       K C  C C G     V+  C    +      D   W LTD    +R
Sbjct: 499 RCKSGFFNLQEDNWKGCDECFCSG-----VSNRCQSSYWTYGKIQDMSGWYLTDLPGRIR 553

Query: 279 LAALSIEEGKSGVLSVSSGAA 299
           +A    +      +S+S+  A
Sbjct: 554 VAPQQDDLDSPQQISISNAEA 574



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 53/175 (30%), Positives = 72/175 (41%), Gaps = 42/175 (24%)

Query: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRK----NGAV----------------------R 154
           SI  A + CQ   CP  +  +  ESC+ +    NG +                       
Sbjct: 716 SIAAAVEVCQ---CPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGE 772

Query: 155 CI-CNENYAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDC--DEVTGQ-C 209
           C+ C ++  GP C++C PG+YG P       C+ C C  N   N     C  D   G  C
Sbjct: 773 CLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLIC 832

Query: 210 RNCLRNTTGFKCERCAPGYYGDARI-AKNCAVCNCGG-------GPCDSVTGECL 256
             C    TG +CERCA GY+G   +   +C  C C         G CDS++G CL
Sbjct: 833 DGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCL 887



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 67/239 (28%), Positives = 91/239 (38%), Gaps = 58/239 (24%)

Query: 82  CDCNGNSNEC-LD---GSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
           C C G++  C LD       C  C+ NT G+ C++C  G+     R A  F     C   
Sbjct: 287 CICYGHARACPLDPATNKSRC-ECEHNTCGDSCDQCCPGFHQKPWR-AGTFLTKTECEAC 344

Query: 138 HLANFAESCY------RKN-----------GAVRCICNENYAGPNCERCAPGYY---GNP 177
           +    AE CY      R+N           G V   C +N AG NCE C  G++   G  
Sbjct: 345 NCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVS 404

Query: 178 LLIGSTCKKCDCSGNSDPNLIFEDCDE------VTGQCRNCLRNTTGFKCERCAPGYYGD 231
                 C+ C C      N +    ++        G C +C     G  C+RCA GY G 
Sbjct: 405 PNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSC-HCKTGFGGVSCDRCARGYTG- 462

Query: 232 ARIAKNCAVCNCGG----------GPC----DSVTGEC--LEEGF-----EPPTGCDKC 269
                +C  CNC G          GPC    +   G+C   + GF     +   GCD+C
Sbjct: 463 ---YPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDEC 518


>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
            sapiens]
          Length = 3118

 Score =  419 bits (1078), Expect = e-116
 Identities = 452/1857 (24%), Positives = 773/1857 (41%), Gaps = 221/1857 (11%)

Query: 57   LGRLPPAAEKCNAGFFHTLS-----------GECVPCDCNGNSNECLDGSGYCVHCQRNT 105
            LG    + E C  GF+   S           G CVPC CNG+S+ C   +  C +CQ +T
Sbjct: 1384 LGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHT 1443

Query: 106  TGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLA-NFAESCYRKN-GAVRC-ICNENYA 162
             G+ CE+C  GY G  ++G P  CQ C CPL   + NF+ SC  +     RC  C   Y 
Sbjct: 1444 AGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYE 1502

Query: 163  GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDP-NLIFEDCDEVTGQCRNCLRNTTGFKC 221
            G  CERCAPGY G+P   G +C++C+C    DP   +   CD VTG C  C    TG KC
Sbjct: 1503 GQYCERCAPGYTGSPGNPGGSCQECEC----DPYGSLPVPCDPVTGFC-TCRPGATGRKC 1557

Query: 222  ERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAA 281
            + C    +  AR    C  C   G  C  +                     L D  RL  
Sbjct: 1558 DGCK---HWHAREGWECVFC---GDECTGLL--------------------LGDLARLEQ 1591

Query: 282  LSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKS 341
            + +    +G L      A ++ +  +      LK  LS +     L    I  AE  + +
Sbjct: 1592 MVMSINLTGPL-----PAPYKMLYGLENMTQELKHLLSPQRAPERL----IQLAEGNLNT 1642

Query: 342  LLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEE 401
            L++++ EL+ +  + +  G+   +++  T   A  L E   ++    + +N K +   E 
Sbjct: 1643 LVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNET 1702

Query: 402  HELSPKEISEKLVLAQK----MLEEIRSRQPFFTQRELVDEEADEAYELLSQAES-WQRL 456
                 +     L   QK    M++E+R R+   TQ+E+ ++E   A  LL + +  +   
Sbjct: 1703 LGTRDEAFERNLEGLQKEIDQMIKELR-RKNLETQKEIAEDELVAAEALLKKVKKLFGES 1761

Query: 457  HNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDH---EKQQ 513
              E   +   + E+L DY  K+ D  + L +A + +R+A   NR  A  Q++    EK++
Sbjct: 1762 RGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREA---NRLFAVNQKNMTALEKKK 1818

Query: 514  ERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLS 573
            E V      +  +L    D L        E++ II     I  ++     EL  K+ +LS
Sbjct: 1819 EAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLS 1878

Query: 574  NLSHD-LVQEAIDHAQDLQQEANELSRKLHS--SDMNGLVQKALDASNVYENIVNYVSEA 630
                D  + E +  A+    + N+ S  L     +   +   A  A   Y NI +Y+ EA
Sbjct: 1879 QEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFKAYSNIKDYIDEA 1938

Query: 631  NETAEFALNTTDRIYDAVSG----IDTQIIYHKDESENLLNQARELQAKAESSSDEAVAD 686
             + A+ A +         +G    +         +S  +LN+A++L    + + D  +  
Sbjct: 1939 EKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVKENEDH-LNG 1997

Query: 687  TSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATA 746
               R+  A AR   L   L+D + +L A    D   +L   +    +AN T  +V     
Sbjct: 1998 LKTRIENADARNGDLLRTLNDTLGKLSAIP-NDTAAKLQAVKDKARQANDTAKDVLAQIT 2056

Query: 747  PMANNLTNWSQNLQHFDSS-----------AYNTAVNSARDAVRNLTEVVPQLLDQLRTV 795
             +  NL    +N      S           + N  +  A   V+NL +   +L+D+L+ +
Sbjct: 2057 ELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPI 2116

Query: 796  EQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLK--AFTS 853
              K    N+  +I  I+ELI Q R  A+ I+VS+   G        RT   ++K  ++ +
Sbjct: 2117 --KELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCI-----RTYKPEIKKGSYNN 2169

Query: 854  LSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLD 913
            + + +K        T  AD  + YLGS     +++ + ++   + +++++G+    +   
Sbjct: 2170 IVVNVK--------TAVADNLLFYLGSAKF-IDFLAIEMRKGKVSFLWDVGSGVGRVEYP 2220

Query: 914  SKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDT 973
               +    +Y+  +   R G++G + +        +              ++LD+D  + 
Sbjct: 2221 DLTIDD--SYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVD-ANA 2277

Query: 974  VFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIY-NMDPSTSVPCARDK 1032
            + +VGG+    K   ++ +  F GC+     +N  I L+NF+    +    T  P   D 
Sbjct: 2278 MLFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDS 2337

Query: 1033 LAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSM--F 1090
                Q       FDG GYA+V    R   +  ++    + RT + + L++ +    +  F
Sbjct: 2338 EGTIQ-------FDGEGYALVSRPIR--WYPNISTVMFKFRTFSSSALLMYLATRDLRDF 2388

Query: 1091 FRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVD--- 1147
              +E+ +G++ V YD G SG    +   +     ND K+   ++     +  I +VD   
Sbjct: 2389 MSVELTDGHIKVSYDLG-SG----MASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDT 2443

Query: 1148 --RRHV---KSMDNEKMKIPFTD-IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQ 1201
                ++    S +N  + +   D IY GG P      R LR  + L   + GC+K  +  
Sbjct: 2444 NQEENIATSSSGNNFGLDLKADDKIYFGGLP----TLRNLRPEVNLK-KYSGCLKDIEIS 2498

Query: 1202 KKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQP 1261
            +  +N+L   + +GV  GC  +++ +    F    F+  +  +    G E   +F T   
Sbjct: 2499 RTPYNILSSPDYVGVTKGCSLENVYT--VSFPKPGFV-ELSPVPIDVGTEINLSFSTKNE 2555

Query: 1262 NGLLFYYASGSDV-------------FSISLDNG-------TVIMDVKGIKVQSVDKQYN 1301
            +G++   + G+               + I L+ G       T    ++ I ++     ++
Sbjct: 2556 SGIILLGSGGTPAPPRRKRRQTGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFH 2615

Query: 1302 DGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQ----- 1356
            DG  H V    +   + + VD++R   +N T   +EQ     KK + GG+P   Q     
Sbjct: 2616 DGREHSVHVERTRGIFTVQVDENRRYMQNLT---VEQ-PIEVKKLFVGGAPPEFQPSPLR 2671

Query: 1357 -YANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKP 1415
                F GCI N     V       DF R     +  +  C                 +  
Sbjct: 2672 NIPPFEGCIWNLVINSVPM-----DFARPVSFKNADIGRC-----------------AHQ 2709

Query: 1416 KASQNKKGGKSKD-APSWDPVALKLPERNTPRNSH--CHLSNSPRAIEHAYQYGGTANSR 1472
            K  +++ G    +     +PV        TP  +H  C   + P  +  + Q+G + NS 
Sbjct: 2710 KLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALLIGSKQFGLSRNSH 2769

Query: 1473 QEFEHLKGDFGAKSQFSIRL--RTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGH 1530
                    D   K++ +I L  RT +  G++FY++     DF T+ L +G   + +++G 
Sbjct: 2770 IAIAF--DDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLGS 2827

Query: 1531 KKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEA-TWKIKGPIYLGG 1589
                     K NDG WH +  +R +  G L +DG      ++ P +A    + G +Y+GG
Sbjct: 2828 GDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDG--ASNRTISPKKADILDVVGMLYVGG 2885

Query: 1590 VAPGKAVKNVQINSIYSFSGCLSNLQL--NGASITSASQTFSVTPCFEGPMETGTYFSTE 1647
            +      + +     YS  GC+ NL +    A +   + +F V  CF    + GTYF   
Sbjct: 2886 LPINYTTRRIG-PVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFAN-AQRGTYFDGT 2943

Query: 1648 GGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIR 1707
             G+      F +GL   + FE R  +++G L+   S   + + + M + +++  V+NG  
Sbjct: 2944 -GFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFHVDNGAG 3002

Query: 1708 DFST--SVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNP--KPIDHREPVF 1763
             F+          LCDG+WH++T  +  + ++L VD        P NP     D  +PVF
Sbjct: 3003 RFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSP-NPASTSADTNDPVF 3061

Query: 1764 VGGVPESLLTPRLAPSKPFTGCIRHFVI---DGHP--VSFSKAALVSGAVSINSCPA 1815
            VGG P+ L    L  S PF GCIR   +    G P  V+F+KA  + G   + SCPA
Sbjct: 3062 VGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPV-SCPA 3117



 Score =  175 bits (444), Expect = 3e-43
 Identities = 88/216 (40%), Positives = 117/216 (54%), Gaps = 12/216 (5%)

Query: 62  PAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
           P   + N   F    G C PC C G++  C D +G C++C+ +T G +C+KCL G+ G+ 
Sbjct: 740 PRHRRVNGTIF---GGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEP 796

Query: 122 IRGAPQFCQPCPCPLPHLA-NFAESCY--RKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
            +G  + CQPC CPL   + NF+ +C+  R  G +   C   Y GP CERCA GY+G P 
Sbjct: 797 TKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS 856

Query: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC 238
           + G +C+ C C+ N D + I   CD ++G C  C   TTG  CE CA GY+GDA  AKNC
Sbjct: 857 VPGGSCQPCQCNDNLDFS-IPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNC 915

Query: 239 AVCNCGGG-----PCDSVTGECLEEGFEPPTGCDKC 269
             C C  G      C S TG+C          CDKC
Sbjct: 916 QPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKC 951



 Score =  132 bits (332), Expect = 3e-30
 Identities = 79/223 (35%), Positives = 106/223 (47%), Gaps = 25/223 (11%)

Query: 57   LGRLPPAAEKCNAGFFHTLS---GECVPCDCNGNSNECLDGS-----GYCVHCQRNTTGE 108
            +G   P  E+C  G+F   S   G C PC CN N +  + GS     G C+ C+  TTG 
Sbjct: 837  VGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGR 896

Query: 109  HCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCER 168
            +CE C DGY GD++    + CQPC C      +F+E C+ + G  +C C  N  G  C++
Sbjct: 897  YCELCADGYFGDAVDA--KNCQPCRCNAG--GSFSEVCHSQTG--QCECRANVQGQRCDK 950

Query: 169  CAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGY 228
            C  G +G  L     C  C+C+     +    DC+E +GQC  C    TG KC+RCA GY
Sbjct: 951  CKAGTFG--LQSARGCVPCNCNSFGSKSF---DCEE-SGQCW-CQPGVTGKKCDRCAHGY 1003

Query: 229  YGDARIAKNCAVCNCG--GGPCDSVTGECLEEGFEPPTGCDKC 269
            +        C  C C   G  CD  TG C+         C KC
Sbjct: 1004 FNFQE--GGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKC 1044



 Score =  110 bits (275), Expect = 1e-23
 Identities = 74/199 (37%), Positives = 98/199 (49%), Gaps = 30/199 (15%)

Query: 65   EKCNAGFFHTLSGE-CVPCDCNGNSNECLD--GSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
            +KC AG F   S   CVPC+CN   ++  D   SG C  CQ   TG+ C++C  GY    
Sbjct: 949  DKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQC-WCQPGVTGKKCDRCAHGYFNFQ 1007

Query: 122  IRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIG 181
              G    C  C C   HL N   +C  K G  RCIC  N  G  C +CAP  +G+ +  G
Sbjct: 1008 EGG----CTACECS--HLGN---NCDPKTG--RCICPPNTIGEKCSKCAPNTWGHSITTG 1056

Query: 182  STCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVC 241
              CK C+CS  +  +L F+ C+  TGQC NC    +G KC  C+ G++   R    C +C
Sbjct: 1057 --CKACNCS--TVGSLDFQ-CNVNTGQC-NCHPKFSGAKCTECSRGHWNYPR----CNLC 1106

Query: 242  NC-----GGGPCDSVTGEC 255
            +C         CDS T +C
Sbjct: 1107 DCFLPGTDATTCDSETKKC 1125



 Score =  102 bits (254), Expect = 3e-21
 Identities = 63/200 (31%), Positives = 87/200 (43%), Gaps = 26/200 (13%)

Query: 65   EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
            ++C  G+F+   G C  C+C+   N C   +G C+ C  NT GE C KC     G SI  
Sbjct: 997  DRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCI-CPPNTIGEKCSKCAPNTWGHSITT 1055

Query: 125  APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
                C+ C C      +F   C    G  +C C+  ++G  C  C+ G++  P      C
Sbjct: 1056 G---CKACNCSTVGSLDF--QCNVNTG--QCNCHPKFSGAKCTECSRGHWNYP-----RC 1103

Query: 185  KKCDC------SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKN 237
              CDC      +   D       C + TGQC  C  N  G  C+RC PG +G DA+    
Sbjct: 1104 NLCDCFLPGTDATTCDSETKKCSCSDQTGQC-TCKVNVEGIHCDRCRPGKFGLDAKNPLG 1162

Query: 238  CAVCNCGGGPCDSVTGECLE 257
            C+ C C G      T +C E
Sbjct: 1163 CSSCYCFG-----TTTQCSE 1177



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 76/261 (29%), Positives = 105/261 (40%), Gaps = 48/261 (18%)

Query: 69  AGFFHTLSGECVPCDCNGNSNECLD------------------GSGYCVHCQRNTTGEHC 110
           AG F T + EC  C+C+G + EC                    G G C++C +NT G +C
Sbjct: 332 AGTFLTKT-ECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINC 390

Query: 111 EKCLDGYIGDSIRGAPQFCQPC-PCPLPHLANFAESCYRKNGAVR-------CICNENYA 162
           E C DG+       +P + +PC PC    + +  E C +     R       C C   + 
Sbjct: 391 ETCTDGFFRPK-GVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFG 449

Query: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCE 222
           G +C+RCA GY G P      CK C+CSG    N      D   G C  C  N  G  C 
Sbjct: 450 GVSCDRCARGYTGYP-----DCKACNCSGLGSKNE-----DPCFGPC-ICKENVEGGDCS 498

Query: 223 RCAPGYYG-DARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTD---ALR 278
           RC  G++       K C  C C G     V+  C    +      D   W LTD    +R
Sbjct: 499 RCKSGFFNLQEDNWKGCDECFCSG-----VSNRCQSSYWTYGKIQDMSGWYLTDLPGRIR 553

Query: 279 LAALSIEEGKSGVLSVSSGAA 299
           +A    +      +S+S+  A
Sbjct: 554 VAPQQDDLDSPQQISISNAEA 574



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 53/175 (30%), Positives = 72/175 (41%), Gaps = 42/175 (24%)

Query: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRK----NGAV----------------------R 154
           SI  A + CQ   CP  +  +  ESC+ +    NG +                       
Sbjct: 716 SIAAAVEVCQ---CPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGE 772

Query: 155 CI-CNENYAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDC--DEVTGQ-C 209
           C+ C ++  GP C++C PG+YG P       C+ C C  N   N     C  D   G  C
Sbjct: 773 CLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLIC 832

Query: 210 RNCLRNTTGFKCERCAPGYYGDARI-AKNCAVCNCGG-------GPCDSVTGECL 256
             C    TG +CERCA GY+G   +   +C  C C         G CDS++G CL
Sbjct: 833 DGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCL 887



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 67/239 (28%), Positives = 91/239 (38%), Gaps = 58/239 (24%)

Query: 82  CDCNGNSNEC-LD---GSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
           C C G++  C LD       C  C+ NT G+ C++C  G+     R A  F     C   
Sbjct: 287 CICYGHARACPLDPATNKSRC-ECEHNTCGDSCDQCCPGFHQKPWR-AGTFLTKTECEAC 344

Query: 138 HLANFAESCY------RKN-----------GAVRCICNENYAGPNCERCAPGYY---GNP 177
           +    AE CY      R+N           G V   C +N AG NCE C  G++   G  
Sbjct: 345 NCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVS 404

Query: 178 LLIGSTCKKCDCSGNSDPNLIFEDCDE------VTGQCRNCLRNTTGFKCERCAPGYYGD 231
                 C+ C C      N +    ++        G C +C     G  C+RCA GY G 
Sbjct: 405 PNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSC-HCKTGFGGVSCDRCARGYTG- 462

Query: 232 ARIAKNCAVCNCGG----------GPC----DSVTGEC--LEEGF-----EPPTGCDKC 269
                +C  CNC G          GPC    +   G+C   + GF     +   GCD+C
Sbjct: 463 ---YPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDEC 518


>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
          Length = 3075

 Score =  394 bits (1011), Expect = e-109
 Identities = 426/1830 (23%), Positives = 765/1830 (41%), Gaps = 214/1830 (11%)

Query: 58   GRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117
            G+LP  +++        L   CVPC CN +S+ C   +G C++C  NT G+HC+ C  GY
Sbjct: 1383 GKLPAGSDRGP----RPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGY 1438

Query: 118  IGDSIRGAPQFCQPCPCPLPHLANFAESCYRK-NGAVRC-ICNENYAGPNCERCAPGYYG 175
             G  + G+   C  C CP    A+F+ +C  + +   RC  C   Y G +CERC+  YYG
Sbjct: 1439 YG-KVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYG 1497

Query: 176  NPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
            NP   G +C+KCDC+ +     +  DCD  +GQC  C    +G +C+ C P +     + 
Sbjct: 1498 NPQTPGGSCQKCDCNPHGS---VHGDCDRTSGQC-VCRLGASGLRCDECEPRH---ILME 1550

Query: 236  KNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVS 295
             +C  C+      D   G  L +                D +  A LS+    +G++ V 
Sbjct: 1551 TDCVSCD------DECVGVLLND---------------LDEIGDAVLSL--NLTGIIPVP 1587

Query: 296  SGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQ 355
             G  +    N  N T YL ++ L E   Q  L KI++        +L   +  ++    +
Sbjct: 1588 YGILS----NLENTTKYLQESLLKE-NMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQK 1642

Query: 356  ASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVL 415
             +R  + + KES D      +L     ++ +K   +N  +    +E  L P    + +  
Sbjct: 1643 VNRATERIFKESQDLAIAIERLQMSITEIMEK-TTLNQTL----DEDFLLPNSTLQNMQQ 1697

Query: 416  AQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQ-AESWQRLHNETRTLFPVVLEQLDDY 474
                L EI   + F    +    E   A +LLSQ  E++Q+   E   L       L  +
Sbjct: 1698 NGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKH 1757

Query: 475  NAKLSDLQ------EALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLS 528
            N +L   +      EA  Q  N++    + N    + ++ H ++++ +  ++ V    L 
Sbjct: 1758 NNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLI 1817

Query: 529  TSADSLT-TPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHA 587
             +A + T   +  L  L+D         A+I     +L + +S  + +  DLV  A DHA
Sbjct: 1818 DAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQRNAV--DLVYRAEDHA 1875

Query: 588  QDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDA 647
             + Q+ A+ L   L   ++  +   A  A+ V+ NI + + E+ E A  A  T       
Sbjct: 1876 AEFQRLADVLYSGL--ENIRNVSLNATSAAYVHYNIQSLIEESEELARDAHRTVTETSLL 1933

Query: 648  VSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSD 707
               + +        S   L +   L  K    + E +++   +          +  + ++
Sbjct: 1934 SESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALE-LSELRNKTNRFQENAVEITRQTNE 1992

Query: 708  AVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAY 767
            ++  L+A  +G  + +  +++ +   A+++ +   +  A ++  L N S +L   +++  
Sbjct: 1993 SLLILRAIPKG-IRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLR 2051

Query: 768  NT---------AVNSARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQT 818
             T         A   A   V+++      L D+L+ +  K    N+S ++  I+ LI+Q 
Sbjct: 2052 ETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPL--KMLEENLSRNLSEIKLLISQA 2109

Query: 819  RSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYL 878
            R  A+ I+V++  D         + S  +   + +L+L +K        T+  D  + YL
Sbjct: 2110 RKQAASIKVAVSADRDCIRAYQPQISSTN---YNTLTLNVK--------TQEPDNLLFYL 2158

Query: 879  GSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPV--SSWPAYFSIVKIERVGKHG 936
            GS  A  +++ + ++   + ++++LG+    +     P+  + W +    + + R G  G
Sbjct: 2159 GSSTA-SDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHS----IHVARFGNIG 2213

Query: 937  KVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFV 996
               L+V  +SS  ++   K  +  G  ++LD++   T+ +VGG+    K   ++ +  F 
Sbjct: 2214 S--LSVKEMSSN-QKSPTKTSKSPGTANVLDVN-NSTLMFVGGLGGQIKKSPAVKVTHFK 2269

Query: 997  GCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDI 1056
            GCL  A LN   I L+N+               R     +Q+   S+ FDGSGY+VV   
Sbjct: 2270 GCLGEAFLNGKSIGLWNYIEREGK--------CRGCFGSSQNEDPSFHFDGSGYSVV--- 2318

Query: 1057 TRRGKFGQVTRFDIEVRTPADNGLILLM--VNGSMFFRLEMRNGYLHVFYDFGFSGGPVH 1114
              +     VT+  +   T + NGL+L +       F  +E+  G + V  D G   GP+ 
Sbjct: 2319 -EKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLG--SGPIT 2375

Query: 1115 LEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKIPFTD--------- 1165
            L   L   + N+  +++I+   +  + ++ V+D  +  + + ++ + P            
Sbjct: 2376 L---LTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLDKD 2432

Query: 1166 -IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYGCPEDS 1224
             IY+GG P    +SR +R  +    +F GC+K  +  +  F+LL    + GV  GC  + 
Sbjct: 2433 PIYVGGLP----RSRVVRRGVTTK-SFVGCIKNLEISRSTFDLLR--NSYGVRKGCLLEP 2485

Query: 1225 LISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDV---------- 1274
            +  R   F    +I    K S     E    F T   +G++   A G DV          
Sbjct: 2486 I--RSVSFLKGGYIELPPK-SLSPESEWLVTFATTNSSGIIL-AALGGDVEKRGDREEAH 2541

Query: 1275 ---FSISLDNGTVIMDVK-----GIK---VQSVDKQYNDGLSHFVISSVSPTRYELIVDK 1323
               FS+ L  G + + V      G++   + +     +DG +H    S+S  R   I+  
Sbjct: 2542 VPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAH----SISLVRNRRII-T 2596

Query: 1324 SRVGSKNPTKGK----IEQTQASEKKFYFGGSP------ISAQYANFTGCISNAYFTRVD 1373
             ++   NP + K    +E    +    Y GG P      +     +F GCI N  F    
Sbjct: 2597 VQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMRRSFHGCIKNLIF---- 2652

Query: 1374 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD 1433
             ++E+ DF          L  C +                +PK + + +  K    P   
Sbjct: 2653 -NLELLDFNSAVGHEQVDLDTCWLS--------------ERPKLAPDAEDSKLLPEPRAF 2697

Query: 1434 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR 1493
            P               C +  +   +  A+Q+G T NS       +     K    + +R
Sbjct: 2698 P-------------EQCVVDAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKLSVELSIR 2744

Query: 1494 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR 1553
            T +S G+I+Y++ Q + D+  L L  GRL +MF++G  + K+      +DG WH V    
Sbjct: 2745 TFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDY 2804

Query: 1554 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN 1613
             +  G + +DG      ++        ++G  YLGG+      + +  N  +S   C+ +
Sbjct: 2805 VKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIG-NITHSIPACIGD 2863

Query: 1614 LQLNGASITSAS--QTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRP 1671
            + +N   +   S    F+V  C+    E GTYF   G   ++ E + +     I  E R 
Sbjct: 2864 VTVNSKQLDKDSPVSAFTVNRCYAVAQE-GTYFDGSGYAALVKEGYKVQSDVNITLEFRT 2922

Query: 1672 RSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQS--LCDGRWHRITV 1729
             S +G L+   +   + + + + +G+V+  VNNG    + +  PK +  LCDG+WH +  
Sbjct: 2923 SSQNGVLLGISTAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQA 2982

Query: 1730 IRDSNVVQLDVDSEVNHVVGP-LNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRH 1788
             +  + + L VD        P      +D   P++VGG P  +    L     F GC+R 
Sbjct: 2983 NKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRK 3042

Query: 1789 FVIDGHP----VSFSKAALVSGAVSINSCP 1814
              +   P      FS+A  + G V ++SCP
Sbjct: 3043 LALIKSPQVQSFDFSRAFELHG-VFLHSCP 3071



 Score =  199 bits (505), Expect = 3e-50
 Identities = 103/248 (41%), Positives = 133/248 (53%), Gaps = 14/248 (5%)

Query: 35  DIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHT----LSGECVPCDCNGNSNE 90
           DI  S+A+      +        G    + E C +G++        G C PC+C+G++ E
Sbjct: 691 DIASSNAIDLVVAADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAE 750

Query: 91  CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLAN-FAESCYRK 149
           C +  G C+ C  NTTG HCE+CL G+ G+  RG P  CQPC CPL   +N F+ +C+  
Sbjct: 751 C-NVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLN 809

Query: 150 NG--AVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTG 207
           +G   V   C   Y+G  CERCA GYYGNP + G +C  CDCSGN DP+     CD VTG
Sbjct: 810 DGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGH-CDSVTG 868

Query: 208 QCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC-----GGGPCDSVTGECLEEGFEP 262
           +C  CL NT G  CERCA G+YGDA  AKNC  C C         C   TG C  +    
Sbjct: 869 ECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVT 928

Query: 263 PTGCDKCV 270
              CD+C+
Sbjct: 929 GQQCDQCL 936



 Score =  127 bits (318), Expect = 1e-28
 Identities = 74/215 (34%), Positives = 110/215 (51%), Gaps = 25/215 (11%)

Query: 65   EKCNAGFFH--TLSGE-CVPCDCNGN-----SNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
            E+C  G++   T+ GE CVPCDC+GN     +  C   +G C+ C  NT G HCE+C DG
Sbjct: 829  ERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADG 888

Query: 117  YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176
            + GD++    + C+ C C +    + +  C+ + G   C C  N  G  C++C  GYYG 
Sbjct: 889  FYGDAVTA--KNCRACECHVK--GSHSAVCHLETGL--CDCKPNVTGQQCDQCLHGYYG- 941

Query: 177  PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK 236
             L  G  C+ C+CS       + + C +  GQC +C+    G +C+RCA G+Y  A    
Sbjct: 942  -LDSGHGCRPCNCSVAGS---VSDGCTD-EGQC-HCVPGVAGKRCDRCAHGFY--AYQDG 993

Query: 237  NCAVCNC--GGGPCDSVTGECLEEGFEPPTGCDKC 269
            +C  C+C      CD  TGEC+         C++C
Sbjct: 994  SCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEEC 1028



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 59/197 (29%), Positives = 83/197 (42%), Gaps = 43/197 (21%)

Query: 79  CVPCDCNGNSNEC------------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
           C  C+C+  + +C                    G G C++C +NT G +CE C+DGY   
Sbjct: 324 CEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRP 383

Query: 121 SIRGAPQFCQPC-PCPLPHLANFAESCYR-------KNGAV--RCICNENYAGPNCERCA 170
             + +P   +PC PC    + + +  C +        NG    +C C E Y G  C+RC 
Sbjct: 384 H-KVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQ 442

Query: 171 PGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDE-VTGQCRNCLRNTTGFKCERCAPGYY 229
            GY   P     TC  C C      N +    DE  TG C  C  N  G  C+RC PG+Y
Sbjct: 443 LGYKDYP-----TCVSCGC------NPVGSASDEPCTGPC-VCKENVEGKACDRCKPGFY 490

Query: 230 G-DARIAKNCAVCNCGG 245
               +  + C+ C C G
Sbjct: 491 NLKEKNPRGCSECFCFG 507



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 62/188 (32%), Positives = 78/188 (41%), Gaps = 21/188 (11%)

Query: 65   EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
            ++C  GF+    G C PCDC    N C   +G CV C  +T G  CE+C DG+ G     
Sbjct: 981  DRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECV-CPPHTQGVKCEECEDGHWG---YD 1036

Query: 125  APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
            A   CQ C C L  + +    C    G   C C   + G  C++C+ GY   P      C
Sbjct: 1037 AEVGCQACNCSL--VGSTHHRCDVVTG--HCQCKSKFGGRACDQCSLGYRDFP-----DC 1087

Query: 185  KKCDCS--GNSDPNLIFED----CDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKN 237
              CDC   G S      E     C E TG C  C  N  G +C  C  G +   A     
Sbjct: 1088 VPCDCDLRGTSGDACNLEQGLCGCVEETGAC-PCKENVFGPQCNECREGTFALRADNPLG 1146

Query: 238  CAVCNCGG 245
            C+ C C G
Sbjct: 1147 CSPCFCSG 1154



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 64/227 (28%), Positives = 87/227 (38%), Gaps = 50/227 (22%)

Query: 82  CDCNGNSNEC-LDGSGYCVHCQ--RNTTGEHCEKCLDGYIGDSIR----GAPQFCQPCPC 134
           C C G+++ C  D +   + CQ   NT GE C +C  GY     R     +   C+ C C
Sbjct: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329

Query: 135 PLPHLANFAESCYR-----------------KNGAVRCICNENYAGPNCERCAPGYYGNP 177
                 N A+ CY                  + G V   C +N  G NCE C  GYY  P
Sbjct: 330 -----HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYY-RP 383

Query: 178 LLIG----STCKKCDCS--GNSDPNLIFEDC------DEVTGQCRNCLRNTTGFKCERCA 225
             +       C+ C+C   G+     I +D        +  GQC  C    TG KC+RC 
Sbjct: 384 HKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQC-PCKEGYTGEKCDRCQ 442

Query: 226 PGYYGDARIAKNCAVCNC---GGGPCDSVTGECLEEGFEPPTGCDKC 269
            GY    +    C  C C   G    +  TG C+ +       CD+C
Sbjct: 443 LGY----KDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACDRC 485


>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
          Length = 1786

 Score =  171 bits (434), Expect = 5e-42
 Identities = 100/280 (35%), Positives = 137/280 (48%), Gaps = 34/280 (12%)

Query: 21   CSRAASGD-----DNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTL 75
            C+R A G          P +     +V     P T +     G      ++C  G  H  
Sbjct: 803  CNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPG--HWG 860

Query: 76   SGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP 135
               C PC CNG++++C   +G C++CQ  T G +CE+CL GY GD I G+   C+PCPCP
Sbjct: 861  FPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCP 920

Query: 136  --LPHLANFAESCYRKNGAVR--CICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSG 191
                    FA SCY+    ++  C+C+  Y G  C+ CA GY+GNP  +G +C+ C C  
Sbjct: 921  DGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHN 980

Query: 192  N---SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC--AVCN---- 242
            N   +DP    E CD+ TG+C  CL +T G  C+ C  GYYGDA + ++C   VCN    
Sbjct: 981  NIDTTDP----EACDKETGRCLKCLYHTEGEHCQFCRFGYYGDA-LQQDCRKCVCNYLGT 1035

Query: 243  ----CGGG--PCDSVTGECLEEGFEPPTGCDKC---VWDL 273
                C G    CD  TG+CL         CD+C    W L
Sbjct: 1036 VQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQL 1075



 Score =  142 bits (359), Expect = 2e-33
 Identities = 180/820 (21%), Positives = 328/820 (40%), Gaps = 120/820 (14%)

Query: 58   GRLPPAAEKCNAGFFHTLS---GECVPCDCNGNSNE-----CLDGSGYCVHCQRNTTGEH 109
            G +    + C +G+F   S   G C PC C+ N +      C   +G C+ C  +T GEH
Sbjct: 949  GYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEH 1008

Query: 110  CEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKN-----GAVRCICNENYAGP 164
            C+ C  GY GD+++   Q C+ C C   +L    E C   +        +C+C  N  G 
Sbjct: 1009 CQFCRFGYYGDALQ---QDCRKCVCN--YLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQ 1063

Query: 165  NCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
            NC+RCAP  +   L  G+ C  C+C+     +     C+E TGQC+ C+    G  C  C
Sbjct: 1064 NCDRCAPNTW--QLASGTGCDPCNCNA---AHSFGPSCNEFTGQCQ-CMPGFGGRTCSEC 1117

Query: 225  APGYYGDARIAKNCAVCNCGGG-----PCDSVTGECL-EEGFEPPTGCDKCVWDLTDALR 278
               ++GD  +   C  C+C         CD  TG+C+  EG E P  CDKC         
Sbjct: 1118 QELFWGDPDV--ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPR-CDKCT-------- 1166

Query: 279  LAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYA--LRKIQINNAE 336
                    G SGV    +        ++  A   ++  +L+ R +++    + ++I+   
Sbjct: 1167 -------RGYSGVFPDCTPC------HQCFALWDVIIAELTNRTHRFLEKAKALKISGVI 1213

Query: 337  NTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKML 396
               +  +  VE  V +      K  L Q  + + + +   L E+A  +   + E+  ++ 
Sbjct: 1214 GPYRETVDSVERKVSEI-----KDILAQSPAAEPLKNIGNLFEEAEKLIKDVTEMMAQV- 1267

Query: 397  YYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVD---EEADEAYELLSQAESW 453
                       ++S+    +    +E+ S Q   T+ E +D   +E  E  E +  ++  
Sbjct: 1268 ---------EVKLSDTTSQSNSTAKELDSLQ---TEAESLDNTVKELAEQLEFIKNSDIR 1315

Query: 454  QRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQ 513
              L + T+  F + LE  +  NA  ++    ++Q+       ED+     ++ ++ +++Q
Sbjct: 1316 GALDSITK-YFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQ 1374

Query: 514  ERVREQM--EVVNMSLSTSADSL--TTPRLTLSELDDIIKNASGIYAEID-GAKSELQVK 568
             R+ +++  ++ ++ LS +A+    T P  + SE +       G     D G +      
Sbjct: 1375 ARLLDELAGKLQSLDLSAAAEMTCGTPPGASCSETE-----CGGPNCRTDEGERKCGGPG 1429

Query: 569  LSNLSNLSHDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVS 628
               L  ++H+  Q+A+D  QD+                       L A    E +   VS
Sbjct: 1430 CGGLVTVAHNAWQKAMDLDQDV-----------------------LSALAEVEQLSKMVS 1466

Query: 629  EANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQAREL--QAKAESSSDEAVAD 686
            EA   A+ A  + + I    +    ++    +E  NL+ Q R    Q  A+  S EAVA+
Sbjct: 1467 EAKLRADEAKQSAEDILLKTNATKEKMDKSNEELRNLIKQIRNFLTQDSADLDSIEAVAN 1526

Query: 687  --TSRRVGGALARKSALKTRLSDAVKQLQAAE--RGDAQQRLGQSRLITEEANRTTMEVQ 742
                  +     +   L   + + V+ L   E     +   + ++ ++ EEA R +    
Sbjct: 1527 EVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASKSAT 1586

Query: 743  --QATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTV-EQKR 799
              + TA M       ++  Q     A   A    +     LT +  +      T+    +
Sbjct: 1587 DVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLFNASQ 1646

Query: 800  PASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEV 839
              S +  +++ ++   AQ    A  I+  +    QSA +V
Sbjct: 1647 RISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDV 1686



 Score =  113 bits (282), Expect = 2e-24
 Identities = 62/174 (35%), Positives = 81/174 (46%), Gaps = 21/174 (12%)

Query: 76  SGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP 135
           +G    CD  G+ +   D +G    C+ N  G  C +C  G  G      P  C+PC C 
Sbjct: 769 TGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFG----FGPSGCKPCECH 824

Query: 136 LPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDP 195
           L    N    C    G  +C C +      C+RC PG++G P     +C+ C C+G++D 
Sbjct: 825 LQGSVN--AFCNPVTG--QCHCFQGVYARQCDRCLPGHWGFP-----SCQPCQCNGHAD- 874

Query: 196 NLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK--NCAVCNCGGGP 247
                DCD VTG+C NC   T G  CERC  GYYGD  I    +C  C C  GP
Sbjct: 875 -----DCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGP 923



 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 77/241 (31%), Positives = 110/241 (45%), Gaps = 52/241 (21%)

Query: 82  CDCNGNSNEC--LDG---------SGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP---- 126
           C C G+++EC  +DG          G+C+ C+ NT G +CE C+D Y     R A     
Sbjct: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329

Query: 127 QFCQPCPCPLPHLA-NFAESCY----RKNGAVRCICNENYAGPNCERCAPGYYGNP---L 178
             C+ C C    ++ +F  + Y      +G V   C  N  G NCE+C P YY +P   +
Sbjct: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDI 389

Query: 179 LIGSTCKKCDC--SGNSDPNLIFEDCDEVT--------GQCRNCLRNTTGFKCERCAPGY 228
              + C++C C  +G+ +  +    CD  T        GQCR C  N  G  C+ C  G+
Sbjct: 390 RDPNFCERCTCDPAGSQNEGI----CDSYTDFSTGLIAGQCR-CKLNVEGEHCDVCKEGF 444

Query: 229 YG----DARIAKNCAVCN-----CGGGPCDSVTGECLEEGFEPPTGCDKCV---WDLTDA 276
           Y     D    K+CA CN      GG PCDS TG C  +       CD+C+   W L++ 
Sbjct: 445 YDLSSEDPFGCKSCA-CNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSND 503

Query: 277 L 277
           L
Sbjct: 504 L 504



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 62/205 (30%), Positives = 83/205 (40%), Gaps = 29/205 (14%)

Query: 76  SGECVPCDCNGNSNEC-LD----------GSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
           S  C  C+CN +S  C  D            G C  CQ NT G +CE+C   Y     R 
Sbjct: 329 SNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERD 388

Query: 125 A--PQFCQPCPCPLPHLANFAESCYRKNG------AVRCICNENYAGPNCERCAPGYYGN 176
              P FC+ C C  P  +     C           A +C C  N  G +C+ C  G+Y  
Sbjct: 389 IRDPNFCERCTCD-PAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDL 447

Query: 177 PLLIGSTCKKCDCSG-NSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
                  CK C C+   + P      CD  TG C  C R  TG  C++C P ++G +   
Sbjct: 448 SSEDPFGCKSCACNPLGTIPG--GNPCDSETGHCY-CKRLVTGQHCDQCLPEHWGLSNDL 504

Query: 236 KNCAVCNC--GG---GPCDSVTGEC 255
             C  C+C  GG     C + +G+C
Sbjct: 505 DGCRPCDCDLGGALNNSCFAESGQC 529



 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 44/120 (36%), Positives = 60/120 (50%), Gaps = 14/120 (11%)

Query: 154 RCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCL 213
           +C C  N  G  C RCAPG +G      S CK C+C      N     C+ VTGQC +C 
Sbjct: 791 QCQCRPNVVGRTCNRCAPGTFG---FGPSGCKPCECHLQGSVNAF---CNPVTGQC-HCF 843

Query: 214 RNTTGFKCERCAPGYYGDARIAKNCAVCNCGG--GPCDSVTGECLE-EGFEPPTGCDKCV 270
           +     +C+RC PG++G      +C  C C G    CD VTGECL  + +     C++C+
Sbjct: 844 QGVYARQCDRCLPGHWG----FPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCL 899



 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 50/161 (31%), Positives = 69/161 (42%), Gaps = 25/161 (15%)

Query: 82  CDCNGNSNECLDGS----------GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQP 131
           CD  G+ NE +  S          G C  C+ N  GEHC+ C +G+  D     P  C+ 
Sbjct: 400 CDPAGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFY-DLSSEDPFGCKS 457

Query: 132 CPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG--NPLLIGSTCKKCD 188
           C C PL  +      C  + G   C C     G +C++C P ++G  N L     C+ CD
Sbjct: 458 CACNPLGTIPG-GNPCDSETG--HCYCKRLVTGQHCDQCLPEHWGLSNDL---DGCRPCD 511

Query: 189 CSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
           C      N     C   +GQC +C  +  G +C    PGYY
Sbjct: 512 CDLGGALN---NSCFAESGQC-SCRPHMIGRQCNEVEPGYY 548



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 15/116 (12%)

Query: 67  CNAGFFHTLSGE---CVPCDCNG-----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYI 118
           C  GF+   S +   C  C CN        N C   +G+C +C+R  TG+HC++CL  + 
Sbjct: 440 CKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHC-YCKRLVTGQHCDQCLPEHW 498

Query: 119 GDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
           G  +      C+PC C L    N   SC+ ++G  +C C  +  G  C    PGYY
Sbjct: 499 G--LSNDLDGCRPCDCDLGGALN--NSCFAESG--QCSCRPHMIGRQCNEVEPGYY 548


>gi|143770880 laminin, beta 4 [Homo sapiens]
          Length = 1761

 Score =  164 bits (416), Expect = 6e-40
 Identities = 91/233 (39%), Positives = 121/233 (51%), Gaps = 33/233 (14%)

Query: 65   EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
            ++C AG+F   S  C PC CN  +  C   +G C +C   TTG +CE+C+DGY G+   G
Sbjct: 848  DRCLAGYFGFPS--CHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSG 905

Query: 125  APQFCQPCPCPLPHLAN--FAESCYRK--NGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
             P  C+PC CP    +N  FA SCY+   +  V C C + Y G  C  C+ G+YGNP + 
Sbjct: 906  QP--CRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRIS 963

Query: 181  GSTCKKCDCSGN---SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN 237
            G+ C+ C C+ N   +DP    E C  VTG+C  CL NT G  C+ C PG+YG A + + 
Sbjct: 964  GAPCQPCACNNNIDVTDP----ESCSRVTGECLRCLHNTQGANCQLCKPGHYGSA-LNQT 1018

Query: 238  CAVCNC------------GGGP--CDSVTGECLEEGFEPPTGCDKCV---WDL 273
            C  C+C            GGG   CD VTG C          CD+C    W+L
Sbjct: 1019 CRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNL 1071



 Score =  109 bits (273), Expect = 2e-23
 Identities = 66/201 (32%), Positives = 88/201 (43%), Gaps = 28/201 (13%)

Query: 79  CVPCDCNGNSNEC------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIR--G 124
           C  C CN +S+ C            L G G C  CQ NT G+HC++C   +  D ++   
Sbjct: 329 CRSCSCNSHSSRCHFDMTTYLASGGLSG-GVCEDCQHNTEGQHCDRCRPLFYRDPLKTIS 387

Query: 125 APQFCQPCPCPLPHLANFAESCYRKNGAV-----RCICNENYAGPNCERCAPGYYGNPLL 179
            P  C PC C      +        + A+     +C+C EN  G  C++C P +YG    
Sbjct: 388 DPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSAT 447

Query: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCA 239
               C+ CDC  N   +L F  CD  TGQC  CL   TG  CE C  GY+G       C+
Sbjct: 448 DPLGCQPCDC--NPLGSLPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWGLGNHLHGCS 504

Query: 240 VCNC--GG---GPCDSVTGEC 255
            C+C  GG     C    G+C
Sbjct: 505 PCDCDIGGAYSNVCSPKNGQC 525



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 76/243 (31%), Positives = 103/243 (42%), Gaps = 54/243 (22%)

Query: 82  CDCNGNSNEC-----LDGS---------GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQ 127
           C CNG+++EC     + G          G CV CQ NT G +CE+C D +     R A  
Sbjct: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAPWRPAAD 323

Query: 128 F----CQPCPC-PLPHLANFAESCYRKNGAVR---C-ICNENYAGPNCERCAPGYYGNPL 178
                C+ C C       +F  + Y  +G +    C  C  N  G +C+RC P +Y +PL
Sbjct: 324 LQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPL 383

Query: 179 LIGS---TCKKCDCS-----------GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
              S    C  C+C             +SDP L       V GQC  C  N  G KC++C
Sbjct: 384 KTISDPYACIPCECDPDGTISGGICVSHSDPAL-----GSVAGQCL-CKENVEGAKCDQC 437

Query: 225 APGYYG-DARIAKNCAVCNC---GGGP---CDSVTGECLEEGFEPPTGCDKCV---WDLT 274
            P +YG  A     C  C+C   G  P   CD  TG+CL   +     C++C    W L 
Sbjct: 438 KPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLG 497

Query: 275 DAL 277
           + L
Sbjct: 498 NHL 500



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 61/192 (31%), Positives = 78/192 (40%), Gaps = 25/192 (13%)

Query: 60  LPPAAEKCNAGFFHTLSGECVPCDCNGNSN---ECLDGSGYCVHCQRNTTGEHCEKCLDG 116
           LP A E+        L    V C C+   +    C    G C  C+    G  C++C  G
Sbjct: 747 LPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQC-QCKPLVVGRCCDRCSTG 805

Query: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAES-CYRKNGAVRCICNENYAGPNCERCAPGYYG 175
                  G    C PC C   H     ++ C +  G  +C C+   +G  C+RC  GY+G
Sbjct: 806 SYDLGHHG----CHPCHC---HPQGSKDTVCDQVTG--QCPCHGEVSGRRCDRCLAGYFG 856

Query: 176 NPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
            P     +C  C C      N   E CD  TG C NC   TTG  CERC  GYYG+    
Sbjct: 857 FP-----SCHPCPC------NRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSG 905

Query: 236 KNCAVCNCGGGP 247
           + C  C C   P
Sbjct: 906 QPCRPCLCPDDP 917



 Score = 85.1 bits (209), Expect = 6e-16
 Identities = 58/187 (31%), Positives = 81/187 (43%), Gaps = 26/187 (13%)

Query: 67   CNAGFFHT-LSGECVPCDCNGNS---NECLDGSGYCV--------HCQRNTTGEHCEKCL 114
            C  G + + L+  C  C C+ +     EC  G G C+         C  N TG  C++C 
Sbjct: 1006 CKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCA 1065

Query: 115  DGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
            DGY  + + G  + CQ C C  P  +  +  C +  G  +C C   Y G  C  C   YY
Sbjct: 1066 DGY-WNLVPG--RGCQSCDCD-PRTSQ-SSHCDQLTG--QCPCKLGYGGKRCSECQENYY 1118

Query: 175  GNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARI 234
            G+P      C  CDC+       I   CD  TG CR C    +G +C+RCA G+  +   
Sbjct: 1119 GDP---PGRCIPCDCNRAGTQKPI---CDPDTGMCR-CREGVSGQRCDRCARGHSQEFPT 1171

Query: 235  AKNCAVC 241
               C +C
Sbjct: 1172 CLQCHLC 1178



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 49/155 (31%), Positives = 65/155 (41%), Gaps = 21/155 (13%)

Query: 36  IEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNA------GFFHTLSGECVPCDCNGNSN 89
           I G   V   DP   S     L +      KC+       G   T    C PCDCN   +
Sbjct: 403 ISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGS 462

Query: 90  ----ECLDGSGYCVHCQRNTTGEHCEKCLDGY--IGDSIRGAPQFCQPCPCPLPHLANFA 143
                C   +G C+ C    TG HCE+C  GY  +G+ + G    C PC C +     ++
Sbjct: 463 LPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWGLGNHLHG----CSPCDCDIG--GAYS 515

Query: 144 ESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
             C  KNG  +C C  +  G +C   APGY+  PL
Sbjct: 516 NVCSPKNG--QCECRPHVTGRSCSEPAPGYFFAPL 548



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 52/191 (27%), Positives = 71/191 (37%), Gaps = 46/191 (24%)

Query: 154 RCICNENYAGPNCERCAPGYYGNPL-----LIGSTCKKCDCSGNS-----DPNLIFEDCD 203
           +C+C  N  GPNCERC   +   P      L  + C+ C C+ +S     D         
Sbjct: 294 QCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGG 353

Query: 204 EVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN----CAVCNC------GGGPC----- 248
              G C +C  NT G  C+RC P +Y D     +    C  C C       GG C     
Sbjct: 354 LSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSD 413

Query: 249 ---DSVTGECL-EEGFE-----------------PPTGCDKCVWDLTDALRLAALSIEEG 287
               SV G+CL +E  E                  P GC  C  +   +L      ++ G
Sbjct: 414 PALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTG 473

Query: 288 KSGVLSVSSGA 298
           +   LS  +GA
Sbjct: 474 QCLCLSYVTGA 484



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 10/107 (9%)

Query: 20   ACSRAASGDDNAFP------FDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFH 73
            AC R A G  N  P       D +  ++        T +    LG       +C   ++ 
Sbjct: 1060 ACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYG 1119

Query: 74   TLSGECVPCDCNGNSNE---CLDGSGYCVHCQRNTTGEHCEKCLDGY 117
               G C+PCDCN    +   C   +G C  C+   +G+ C++C  G+
Sbjct: 1120 DPPGRCIPCDCNRAGTQKPICDPDTGMC-RCREGVSGQRCDRCARGH 1165



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 28/95 (29%), Positives = 39/95 (41%), Gaps = 13/95 (13%)

Query: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
           G+   KC   G+     +   C  + GQC+ C     G  C+RC+ G Y        C  
Sbjct: 765 GAVACKCHPQGS-----VGSSCSRLGGQCQ-CKPLVVGRCCDRCSTGSYDLGH--HGCHP 816

Query: 241 CNCG-----GGPCDSVTGECLEEGFEPPTGCDKCV 270
           C+C         CD VTG+C   G      CD+C+
Sbjct: 817 CHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCL 851


>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
          Length = 1609

 Score =  159 bits (401), Expect = 3e-38
 Identities = 191/849 (22%), Positives = 329/849 (38%), Gaps = 180/849 (21%)

Query: 79   CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP--- 135
            CV C CNG+S  C   +G C +C+ NT G HCEKC DGY GDS  G    CQPCPCP   
Sbjct: 721  CVLCACNGHSETCDPETGVC-NCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGS 779

Query: 136  ----LPHLANFA-------------ESC--------YRKNGAVR----CICNENY----- 161
                +P                   E C          +NG VR    C C++N      
Sbjct: 780  SCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAV 839

Query: 162  -----------------AGPNCERCAPGYYGNPLLIGST--CKKCDCS--GNSDPNLIFE 200
                             AG  C+RC  G++GNPL       CK C+C+  G         
Sbjct: 840  GNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQ---S 896

Query: 201  DCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC-----GGGPCDSVTGEC 255
             C+ VTGQC  CL + TG  C  C PG+Y + +  + C  C+C       G CD  TG+C
Sbjct: 897  SCNPVTGQCE-CLPHVTGQDCGACDPGFY-NLQSGQGCERCDCHALGSTNGQCDIRTGQC 954

Query: 256  LEE----------------GFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAA 299
              +                GF  P GC  C     D     +LS++    G      G  
Sbjct: 955  ECQPGITGQHCERCEVNHFGF-GPEGCKPC-----DCHPEGSLSLQCKDDGRCECREGFV 1008

Query: 300  AHR---------------HVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLS 344
             +R                  E  A   L+K K+++        ++++   E+ + +L +
Sbjct: 1009 GNRCDQCEENYFYNRSWPGCQECPACYRLVKDKVAD-------HRVKLQELESLIANLGT 1061

Query: 345  DVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHEL 404
              E + ++  +   K    ++E MD +  A  + +   ++ D++Q +NN +       + 
Sbjct: 1062 GDEMVTDQAFEDRLKE--AEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQN 1119

Query: 405  SPKEISEKLVLAQKMLEEIRSRQPF--FTQRELVDEEADEAYELLSQAES------WQRL 456
                I E   LA++    + + +       REL   +   A   ++Q ES         L
Sbjct: 1120 IRNTIEETGNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLL 1179

Query: 457  HNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVR-----------DAEDMNRATAAR 505
              E R L     ++ DD         +   +A N +            + E++NR     
Sbjct: 1180 AEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQA 1239

Query: 506  Q---RDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDD--IIKNASGIYAEIDG 560
            +   +D EKQ  RV E+ +         A  +      LS LD   +   A+ I  E + 
Sbjct: 1240 KNISQDLEKQAARVHEEAK----RAGDKAVEIYASVAQLSPLDSETLENEANNIKMEAEN 1295

Query: 561  AKSELQVKLSNLSNLSHDL------VQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKAL 614
             +  +  KL +  +L  D+      V+  ++  +  QQ A++L  +  ++       KAL
Sbjct: 1296 LEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAA-------KAL 1348

Query: 615  DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQA 674
                          EA +     L   + I + +   D ++  +K  +E  L +   +  
Sbjct: 1349 ------------AEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAIN- 1395

Query: 675  KAESSSDEAVADTSRRVGGALARKSALKT------RLSDAVKQLQAAERGDAQQRLGQSR 728
            +  + ++E   +  + +G A A  +  K       R++ AV++   + + +A++   +  
Sbjct: 1396 QTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVT 1455

Query: 729  LITEEANRTTMEVQQATAPMANNLTNWSQNLQ---HFDSSAYNTAVNS--ARDAVRNLTE 783
             +  E N    ++Q+A   +     +  Q++        +A    +N+  A+++V +L  
Sbjct: 1456 DLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLLS 1515

Query: 784  VVPQLLDQL 792
            ++  LL+QL
Sbjct: 1516 IINDLLEQL 1524



 Score =  115 bits (289), Expect = 3e-25
 Identities = 62/181 (34%), Positives = 88/181 (48%), Gaps = 28/181 (15%)

Query: 76  SGECVPCDCNGNSNECL---------DGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
           + EC+PCDCNG S EC             G+C +CQ NT G HCE+C + +      G  
Sbjct: 336 ASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFR---LGNN 392

Query: 127 QFCQPCPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCK 185
           + C  C C P+  L+   +S        RC C     G  C+RC PG++    L  + C+
Sbjct: 393 EACSSCHCSPVGSLSTQCDS------YGRCSCKPGVMGDKCDRCQPGFHS---LTEAGCR 443

Query: 186 KCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCG 244
            C C    DP+   ++C+  TG+C  C  N  GF CERC PG++  ++   + C  C C 
Sbjct: 444 PCSC----DPSGSIDECNIETGRC-VCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCF 498

Query: 245 G 245
           G
Sbjct: 499 G 499



 Score =  103 bits (257), Expect = 2e-21
 Identities = 65/187 (34%), Positives = 88/187 (47%), Gaps = 32/187 (17%)

Query: 101 CQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNEN 160
           C     G+ CE CL GY     R  P      PC L      +E+C  + G   C C +N
Sbjct: 692 CPVGYGGQFCEMCLSGY----RRETPNLGPYSPCVLCACNGHSETCDPETGV--CNCRDN 745

Query: 161 YAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGF 219
            AGP+CE+C+ GYYG+      S C+ C C G S   ++ +  + V   C NC   TTG 
Sbjct: 746 TAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVV---CTNCPTGTTGK 802

Query: 220 KCERCAPGYYGDARIAKN-----CAVCNCGG-------GPCDSVTGECLE-----EGFEP 262
           +CE C  GY+GD  + +N     C +C C         G C+ +TGECL+      GF  
Sbjct: 803 RCELCDDGYFGDP-LGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFY- 860

Query: 263 PTGCDKC 269
              CD+C
Sbjct: 861 ---CDRC 864



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 159/821 (19%), Positives = 312/821 (38%), Gaps = 152/821 (18%)

Query: 67   CNAGFFHTLSGE-CVPCDCN--GNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 122
            C+ GF++  SG+ C  CDC+  G++N +C   +G C  CQ   TG+HCE+C   + G   
Sbjct: 919  CDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQC-ECQPGITGQHCERCEVNHFG--- 974

Query: 123  RGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGS 182
               P+ C+PC C   H         + +G  RC C E + G  C++C   Y+ N    G 
Sbjct: 975  -FGPEGCKPCDC---HPEGSLSLQCKDDG--RCECREGFVGNRCDQCEENYFYNRSWPG- 1027

Query: 183  TCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARI---AKNCA 239
             C++C                                 C R       D R+        
Sbjct: 1028 -CQECPA-------------------------------CYRLVKDKVADHRVKLQELESL 1055

Query: 240  VCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAA 299
            + N G G  + VT +  E+  +      +   ++ D LR  A  +++    ++       
Sbjct: 1056 IANLGTGD-EMVTDQAFEDRLK------EAEREVMDLLR-EAQDVKDVDQNLMD-----R 1102

Query: 300  AHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRK 359
              R  N +++ I  L+   +  E    L +    + ENT + L+      +EK   A+  
Sbjct: 1103 LQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVENT-ERLIEIASRELEKAKVAAAN 1161

Query: 360  GQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKM 419
              + Q ES    N+ + L E+A  + ++ ++  + ++   +    +  E    L      
Sbjct: 1162 VSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLL------ 1215

Query: 420  LEEIRSRQPFFTQRELVDEEADEAYELLSQAESW-QRLHNETRTLFPVVLEQLDDYNAKL 478
            L  +        + E ++ + ++A  +    E    R+H E +      +E      A+L
Sbjct: 1216 LRTLAGENQTAFEIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASV-AQL 1274

Query: 479  SDL-QEALDQALNYVR-DAEDMNRATAARQRDHEKQQERVR-EQMEVVNMSLSTSADSLT 535
            S L  E L+   N ++ +AE++ +    + +D+E  +E +R +++EV N+      +  T
Sbjct: 1275 SPLDSETLENEANNIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQT 1334

Query: 536  TPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEAN 595
                           A  + A  D AK+               L +EA    +D  QEAN
Sbjct: 1335 ---------------ADQLLARADAAKA---------------LAEEAAKKGRDTLQEAN 1364

Query: 596  ELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQI 655
            ++   L   D     ++  D     E  +  +   N+T   A   T     A+       
Sbjct: 1365 DILNNLKDFD-----RRVNDNKTAAEEALRKIPAINQTITEANEKTREAQQALGSAAAD- 1418

Query: 656  IYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAA 715
                 E++N  ++A  + +  + ++    A+  R      A  + L   +++ +KQLQ A
Sbjct: 1419 ---ATEAKNKAHEAERIASAVQKNATSTKAEAER----TFAEVTDLDNEVNNMLKQLQEA 1471

Query: 716  ER------GDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNT 769
            E+       DA Q +  + + ++ A    +  ++A                         
Sbjct: 1472 EKELKRKQDDADQDMMMAGMASQAAQEAEINARKA-----------------------KN 1508

Query: 770  AVNSARDAVRNLTEVVPQL----LDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKI 825
            +V S    + +L E + QL    L++L  +E     +     +  +   ++   + A K 
Sbjct: 1509 SVTSLLSIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAKKQ 1568

Query: 826  QVSMMFDGQSAVEV-HSRTSMDDLKAFTSLSLYMKPPVKRP 865
            + ++M   +   E+     +++D++       +  P +++P
Sbjct: 1569 EAAIMDYNRDIEEIMKDIRNLEDIRKTLPSGCFNTPSIEKP 1609



 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 73/266 (27%), Positives = 109/266 (40%), Gaps = 38/266 (14%)

Query: 27  GDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAE------KCNAGFFHTLSGECV 80
           G  +A+ FD    ++   Q+    ++ RV L RL    +      K    +++ +S   V
Sbjct: 227 GRPSAYNFD----NSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAV 282

Query: 81  P--CDCNGNSNECLDGS--GYCVHCQRNTTGEHCEKCLDGYIGDSIRGA----PQFCQPC 132
              C CNG+++EC+         +C+ NT G  CEKCL  +     R A       C PC
Sbjct: 283 GGRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPC 342

Query: 133 PC-PLPHLANFAESCYRKNG-AVRCI-CNENYAGPNCERCAPGYY--GNPLLIGSTCKKC 187
            C        F    YR  G    C  C +N  G +CERC   ++  GN       C  C
Sbjct: 343 DCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGN----NEACSSC 398

Query: 188 DCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG- 246
            C   S    +   CD   G+C +C     G KC+RC PG++  +     C  C+C    
Sbjct: 399 HC---SPVGSLSTQCDSY-GRC-SCKPGVMGDKCDRCQPGFH--SLTEAGCRPCSCDPSG 451

Query: 247 ---PCDSVTGECLEEGFEPPTGCDKC 269
               C+  TG C+ +       C++C
Sbjct: 452 SIDECNIETGRCVCKDNVEGFNCERC 477



 Score = 75.1 bits (183), Expect = 6e-13
 Identities = 43/107 (40%), Positives = 52/107 (48%), Gaps = 11/107 (10%)

Query: 155 CICNENYAGPNCERCAPGYYGNPLLIG--STCKKCDCSGNSDPNLIFEDCDEVTGQCRNC 212
           C C   Y G  CE C  GY      +G  S C  C C+G+S      E CD  TG C NC
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHS------ETCDPETGVC-NC 742

Query: 213 LRNTTGFKCERCAPGYYGD--ARIAKNCAVCNCGGGPCDSVTGECLE 257
             NT G  CE+C+ GYYGD  A  + +C  C C GG   +V  +  E
Sbjct: 743 RDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKE 789



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 3/44 (6%)

Query: 65  EKCNAGFFHTLSGE---CVPCDCNGNSNECLDGSGYCVHCQRNT 105
           E+C  GFF+  S     C PC C G+S+ C +  GY V+   +T
Sbjct: 475 ERCKPGFFNLESSNPRGCTPCFCFGHSSVCTNAVGYSVYSISST 518


>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
          Length = 1798

 Score =  159 bits (401), Expect = 3e-38
 Identities = 83/216 (38%), Positives = 115/216 (53%), Gaps = 22/216 (10%)

Query: 79   CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP--L 136
            C PC CNG+++EC   +G C+ C+ +T GEHCE+C+ G+ GD        C+PCPCP   
Sbjct: 874  CRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGP 933

Query: 137  PHLANFAESCYRK--NGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSD 194
                +FA SC++   +  + C C   Y G  CE CAPG++G+P   G  C+ C+CSGN D
Sbjct: 934  GSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNID 993

Query: 195  PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC---GGGP---- 247
            P +  + CD  TGQC  CL +T G  C  C PG++G A   ++C  C C   G  P    
Sbjct: 994  P-MDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQA-ARQSCHRCTCNLLGTNPQQCP 1051

Query: 248  ------CDSVTGECLEEGFEPPTGCDKCV---WDLT 274
                  CD  +G+C          CD+C    W+LT
Sbjct: 1052 SPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLT 1087



 Score =  113 bits (283), Expect = 1e-24
 Identities = 187/837 (22%), Positives = 311/837 (37%), Gaps = 131/837 (15%)

Query: 65   EKCNAGFFHTLS---GECVPCDCNGN-----SNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
            E C  G F   S   G C  C+C+GN      + C   +G C+ C  +T G HC  C  G
Sbjct: 966  EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPG 1025

Query: 117  YIGDSIRGAPQFCQPCPCPL----PHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172
            + G + R   Q C  C C L    P      + C+    + +C C  N  GP+C+RCAP 
Sbjct: 1026 FHGQAAR---QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPN 1082

Query: 173  YYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA 232
            ++   L  G  C+ C C  +         C+E TGQC +C     G  C  C   ++GD 
Sbjct: 1083 FWN--LTSGHGCQPCACHPSRARG---PTCNEFTGQC-HCRAGFGGRTCSECQELHWGDP 1136

Query: 233  RIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEG 287
             +   C  C+C         C   TG C          CD+C                 G
Sbjct: 1137 GL--QCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCA---------------RG 1179

Query: 288  KSGVLSVSSGAAA-----HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSL 342
             SG+        A      R V ++ A    L+ +  E +    L   +  ++   M+  
Sbjct: 1180 FSGIFPACHPCHACFGDWDRVVQDLAARTQRLEQRAQELQQTGVLGAFE--SSFWHMQEK 1237

Query: 343  LSDVEELVEKEN-QASRKGQLVQ------KESMDTINHASQLVEQAHDMRDKIQEINNKM 395
            L  V+ +V   N  A+   QLV+      +E  +   H +QL     D++D+    N+ +
Sbjct: 1238 LGIVQGIVGARNTSAASTAQLVEATEELRREIGEATEHLTQLEADLTDVQDENFNANHAL 1297

Query: 396  LYYGEEH---ELSPKEISEKLVLAQ--KMLEEIRSRQPFFTQRELVDEEAD-EAYELLSQ 449
                 +     L+ +++ + L L +    L    S +   +Q    +  A+  A  + S 
Sbjct: 1298 SGLERDRLALNLTLRQLDQHLDLLKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSP 1357

Query: 450  AESWQRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQ--ALNYVRDAEDMNRATAARQR 507
              +     + T  L      Q +D+N+K    Q AL +  A  +     D+N        
Sbjct: 1358 VSNSASARHRTEALMDA---QKEDFNSKHMANQRALGKLSAHTHTLSLTDINELVCGAPG 1414

Query: 508  DH------------EKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGI- 554
            D               +  + R      N + +T+  +L   R T +EL   +     I 
Sbjct: 1415 DAPCATSPCGGAGCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRALAEGGSIL 1474

Query: 555  --YAEIDGAKSELQVKLS---NLSNLSHDLVQEAIDHAQDLQQEANELSRKLHSSDMNGL 609
               AE     SE Q +     + +N S   V++A    Q+L Q   +   +   +D + +
Sbjct: 1475 SRVAETRRQASEAQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQ-EGADPDSI 1533

Query: 610  VQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQA 669
                + A+ V E  +   +E  +    A+    R    V  I  + +     +E LL  A
Sbjct: 1534 ---EMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQDA 1590

Query: 670  RELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRL 729
            R  ++ AE    +A                     +  A+++ Q A+ G AQ  +  +  
Sbjct: 1591 RRARSWAEDEKQKA-------------------ETVQAALEEAQRAQ-GIAQGAIRGAVA 1630

Query: 730  ITEEANRTTMEVQQATAPMANNLTNWSQNLQHFD-------------SSAYNTAVNSARD 776
             T +  +T  +VQ+  A     L++  +  +  D             S A +TA  +A  
Sbjct: 1631 DTRDTEQTLYQVQERMAGAERALSSAGERARQLDALLEALKLKRAGNSLAASTAEETAGS 1690

Query: 777  AVRNLTEVVPQLL-----DQLRTVE--QKRPASNVSASIQRIRELIAQTRSVASKIQ 826
            A +   +   QLL     DQ +TV+   +R A  V A+  R  +L  + R +    Q
Sbjct: 1691 A-QGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAAQ 1746



 Score =  103 bits (258), Expect = 1e-21
 Identities = 58/173 (33%), Positives = 81/173 (46%), Gaps = 25/173 (14%)

Query: 80  VPCDCNGN---SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136
           +PC CN     S+EC    G C+ C+    G  C+ C  GY G      P  CQ C C  
Sbjct: 781 LPCQCNPQGSLSSECNPHGGQCL-CKPGVVGRRCDLCAPGYYG----FGPTGCQACQC-- 833

Query: 137 PHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPN 196
            H    +  C + +G  +C+C     G  C+RC  G +G P     +C+ C C+G++D  
Sbjct: 834 SHEGALSSLCEKTSG--QCLCRTGAFGLRCDRCQRGQWGFP-----SCRPCVCNGHAD-- 884

Query: 197 LIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARI--AKNCAVCNCGGGP 247
               +C+  TG C  C  +T G  CERC  G++GD R+     C  C C  GP
Sbjct: 885 ----ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGP 933



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 60/205 (29%), Positives = 88/205 (42%), Gaps = 29/205 (14%)

Query: 76  SGECVPCDCNGNSNEC--------LDGS---GYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
           S  C  C+C+G+++ C          G+   G C  CQ NT G HCE C   +  D  + 
Sbjct: 341 SHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKD 400

Query: 125 A--PQFCQPCPCPLPHLANFAESCYRKNGAV------RCICNENYAGPNCERCAPGYYGN 176
              P  C+ C C  P  +     C   +         +C C E+  G  C++C  G++G 
Sbjct: 401 LRDPAVCRSCDCD-PMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGL 459

Query: 177 PLLIGSTCKKCDCSGNSD-PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
            +     C++C C+     P      CD  +G C  C R  TG  C+RC PG++G +   
Sbjct: 460 SISDRLGCRRCQCNARGTVPG--STPCDPNSGSC-YCKRLVTGRGCDRCLPGHWGLSHDL 516

Query: 236 KNCAVCNCGGG-----PCDSVTGEC 255
             C  C+C  G      CD  TG+C
Sbjct: 517 LGCRPCDCDVGGALDPQCDEGTGQC 541



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 72/235 (30%), Positives = 102/235 (43%), Gaps = 40/235 (17%)

Query: 82  CDCNGNSNECLDGSGYCVH----------CQRNTTGEHCEKCLDGYIGDSIR----GAPQ 127
           C C G+++EC    G   H          C+ NT G +CE+C D Y     R    G   
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSH 342

Query: 128 FCQPCPCP-LPHLANFAESCYRKNGAVR---CI-CNENYAGPNCERCAPGYYGNP---LL 179
            C+ C C    H  +F  + Y  +G V    C  C  N AG +CE C P +Y +P   L 
Sbjct: 343 ACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLR 402

Query: 180 IGSTCKKCDCS--GNSDPNLIFEDCDE----VTGQCRNCLRNTTGFKCERCAPGYYGDAR 233
             + C+ CDC   G+ D        D     V+GQCR C  +  G +C++C  G++G + 
Sbjct: 403 DPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCR-CKEHVVGTRCQQCRDGFFGLSI 461

Query: 234 IAK-NCAVCNC-------GGGPCDSVTGECLEEGFEPPTGCDKCV---WDLTDAL 277
             +  C  C C       G  PCD  +G C  +      GCD+C+   W L+  L
Sbjct: 462 SDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDL 516



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 55/168 (32%), Positives = 79/168 (47%), Gaps = 31/168 (18%)

Query: 79  CVPCDCNGNSNECLDG--------------SGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
           C  CDC+   ++  DG              SG C  C+ +  G  C++C DG+ G SI  
Sbjct: 407 CRSCDCDPMGSQ--DGGRCDSHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFGLSISD 463

Query: 125 APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG-NPLLIGST 183
               C+ C C        +  C   +G+  C C     G  C+RC PG++G +  L+G  
Sbjct: 464 RLG-CRRCQCNARGTVPGSTPCDPNSGS--CYCKRLVTGRGCDRCLPGHWGLSHDLLG-- 518

Query: 184 CKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
           C+ CDC   G  DP      CDE TGQC +C ++  G +CE+  PGY+
Sbjct: 519 CRPCDCDVGGALDPQ-----CDEGTGQC-HCRQHMVGRRCEQVQPGYF 560



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 46/144 (31%), Positives = 66/144 (45%), Gaps = 22/144 (15%)

Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGST-CKKCDCSG 191
           PC      + +  C    G  +C+C     G  C+ CAPGYYG     G T C+ C CS 
Sbjct: 782 PCQCNPQGSLSSECNPHGG--QCLCKPGVVGRRCDLCAPGYYG----FGPTGCQACQCSH 835

Query: 192 NSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG--GPCD 249
               + +   C++ +GQC  C     G +C+RC  G +G      +C  C C G    C+
Sbjct: 836 EGALSSL---CEKTSGQCL-CRTGAFGLRCDRCQRGQWG----FPSCRPCVCNGHADECN 887

Query: 250 SVTGECLEEGFEPPTG---CDKCV 270
           + TG CL  G    TG   C++C+
Sbjct: 888 THTGACL--GCRDHTGGEHCERCI 909



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 38/120 (31%), Positives = 55/120 (45%), Gaps = 19/120 (15%)

Query: 65  EKCNAGFFHTLSGE---CVPCDCNGN-----SNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
           ++C  GFF     +   C  C CN       S  C   SG C +C+R  TG  C++CL G
Sbjct: 450 QQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSC-YCKRLVTGRGCDRCLPG 508

Query: 117 YIGDS--IRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
           + G S  + G    C+PC C +    +    C    G  +C C ++  G  CE+  PGY+
Sbjct: 509 HWGLSHDLLG----CRPCDCDVGGALD--PQC--DEGTGQCHCRQHMVGRRCEQVQPGYF 560



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 18/138 (13%)

Query: 62   PAAEKCNAGFFHTLSGE-CVPCDCN---GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117
            P+ ++C   F++  SG  C PC C+        C + +G C HC+    G  C +C + +
Sbjct: 1074 PSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQC-HCRAGFGGRTCSECQELH 1132

Query: 118  IGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNP 177
             GD        C  C C    +      C+R  G   C C    +G  C++CA G+ G  
Sbjct: 1133 WGDP----GLQCHACDCDSRGIDT--PQCHRFTG--HCSCRPGVSGVRCDQCARGFSG-- 1182

Query: 178  LLIGSTCKKCD-CSGNSD 194
              I   C  C  C G+ D
Sbjct: 1183 --IFPACHPCHACFGDWD 1198



 Score = 39.3 bits (90), Expect = 0.035
 Identities = 68/328 (20%), Positives = 134/328 (40%), Gaps = 47/328 (14%)

Query: 341  SLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAH-DMRDKIQEINNKMLYYG 399
            S+LS V E   + ++A ++ Q     ++D  N +   VEQA+ ++++ IQ + + +   G
Sbjct: 1472 SILSRVAETRRQASEAQQRAQA----ALDKANASRGQVEQANQELQELIQSVKDFLNQEG 1527

Query: 400  EEH-----------ELSPKEISEKLV-LAQKMLEEIRSRQPF--FTQRELVD-EEADEAY 444
             +            ELS    +E++  LA  + E +RS         R + D   A++  
Sbjct: 1528 ADPDSIEMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLL 1587

Query: 445  ELLSQAESWQRLHNETRTLFPVVLEQLDDYN-----------AKLSDLQEALDQALNYVR 493
            +   +A SW     +        LE+                A   D ++ L Q    + 
Sbjct: 1588 QDARRARSWAEDEKQKAETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMA 1647

Query: 494  DAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASG 553
             AE    +   R R  +   E ++ +    +++ ST+ ++  + +    E + +++   G
Sbjct: 1648 GAERALSSAGERARQLDALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLG 1707

Query: 554  IYAEIDGAKSE--------LQVKLSNLSNLSHDLVQEAIDHAQDLQQ-----EANELSRK 600
               +   A +E         Q +   L + + DL+Q A D  Q LQ+     E NE + +
Sbjct: 1708 DQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALE 1767

Query: 601  LHSSDMNGL---VQKALDASNVYENIVN 625
              ++ ++GL   ++  L A N+   I N
Sbjct: 1768 SKAAQLDGLEARMRSVLQAINLQVQIYN 1795


>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
          Length = 1575

 Score =  145 bits (367), Expect = 3e-34
 Identities = 84/224 (37%), Positives = 107/224 (47%), Gaps = 26/224 (11%)

Query: 65  EKCNAGFFHTLS-----GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
           E C  G+   +        CVPC CN +   C   +G CV C  +T G  CE+CL G+ G
Sbjct: 685 ESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDPNTGICV-CSHHTEGPSCERCLPGFYG 742

Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPL 178
           +   G    CQPCPCP       A +   ++  V C  C     G  CE C  G++G+PL
Sbjct: 743 NPFAGQADDCQPCPCP----GQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPL 798

Query: 179 -LIG--STCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA--- 232
            L G    C +C CSGN DPN +  +CD ++G C  CL NTTG  CE C  G+YG A   
Sbjct: 799 GLFGHPQPCHQCQCSGNVDPNAV-GNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAP 857

Query: 233 RIAKNCAVCNCGGG-------PCDSVTGECLEEGFEPPTGCDKC 269
           R A  C  C+C          PCD VTG+C          C +C
Sbjct: 858 RPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRC 901



 Score =  119 bits (297), Expect = 4e-26
 Identities = 193/862 (22%), Positives = 320/862 (37%), Gaps = 119/862 (13%)

Query: 29   DNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPA-----AEKCNAGFFHTLSG------ 77
            D+  P    G SA      PE+ E  V     PP       E C+ GFF    G      
Sbjct: 750  DDCQPCPCPGQSAC--TTIPESRE--VVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQ 805

Query: 78   ECVPCDCNGNSN-----ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP-QFCQP 131
             C  C C+GN +      C   SG+C+ C  NTTG+HCE C +G+ G ++   P   C P
Sbjct: 806  PCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMP 865

Query: 132  CPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCS- 190
            C C      +    C    G  +C C  +    +C RC PG++   L  G  C+ C C  
Sbjct: 866  CSCHPQGSVSEQMPCDPVTG--QCSCLPHVTARDCSRCYPGFF--DLQPGRGCRSCKCHP 921

Query: 191  -GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCD 249
             G+ +     + C   TGQC  C    TG  C+RC  G++G +   K C  C C   P  
Sbjct: 922  LGSQE-----DQCHPKTGQC-TCRPGVTGQACDRCQLGFFGFS--IKGCRACRC--SPLG 971

Query: 250  SVTGECLEE-------GFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHR 302
            + + +C E        GFE    CD+C     D   L A    +G       S  A    
Sbjct: 972  AASAQCHENGTCVCRPGFE-GYKCDRC----HDNFFLTA----DGTHCQQCPSCYALVKE 1022

Query: 303  HVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKGQL 362
               ++ A + L +  L   +       + I   E     +      L       +R+  L
Sbjct: 1023 EAAKLKARLTLTEGWLQGSDCGSPWGPLDILLGEAPRGDVYQGHHLL-----PGAREAFL 1077

Query: 363  VQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEE 422
             Q  S++    A+         R+++Q +N          + +  ++++   + +   EE
Sbjct: 1078 EQMMSLEGAVKAA---------REQLQRLNKGARCAQAGSQKTCTQLADLEAVLESSEEE 1128

Query: 423  IRSRQPFFTQRELVDEEADEAYE---LLSQAESWQRLHNETRT-LFPVVLEQLDDYNAKL 478
            I          E+  E   +  +   L ++A +  R H +T T +       L   N   
Sbjct: 1129 ILHAAAILASLEIPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRALLASNTSY 1188

Query: 479  SDLQEALD--QALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTT 536
            + L   L+   AL   RD ED  +   A Q+        V  + E V ++      + T 
Sbjct: 1189 ALLWNLLEGRVALETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESV-LATVQQVGADTA 1247

Query: 537  PRLTLSELDDIIKNASGIYAEIDGAKSE-LQVKLSNLSNLSHDLVQEAIDHAQDLQQEAN 595
            P L L      +   S   AE  G K++ L+  +++  +++ +  +     AQ   ++  
Sbjct: 1248 PYLALLASPGALPQKS--RAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQATLRQTE 1305

Query: 596  ELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQI 655
             L+ KLH      L Q                S + + A   +     +   + G+  Q 
Sbjct: 1306 PLT-KLHQEARAALTQ---------------ASSSVQAATVTVMGARTLLADLEGMKLQF 1349

Query: 656  IYHKDESENLLNQARELQAKAESSSDEAVADT-------SRRVGGALARKSALKTR---- 704
               KD++         LQ KA+S SD  +ADT        R +G A    S+ K +    
Sbjct: 1350 PRPKDQA--------ALQRKADSVSDRLLADTRKKTKQAERMLGNAAPLSSSAKKKGREA 1401

Query: 705  ---LSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQH 761
                 D+ K  +A  R   Q     SRL ++         QQ  A  A            
Sbjct: 1402 EVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQASQQVLASEARRQELEEAERVG 1461

Query: 762  FDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVE-QKRPASNVSA---SIQRIRELIAQ 817
               S     +  +R ++    E + +LL +L +++  + PA  ++    +++R+R  +  
Sbjct: 1462 AGLSEMEQQIRESRISLEKDIETLSELLARLGSLDTHQAPAQALNETQWALERLRLQLGS 1521

Query: 818  TRSVASKIQVSMMFDGQSAVEV 839
              S+  K+ +      Q  +++
Sbjct: 1522 PGSLQRKLSLLEQESQQQELQI 1543



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 68/201 (33%), Positives = 91/201 (45%), Gaps = 22/201 (10%)

Query: 82  CDCNGNSNEC---LDGSGYCVHCQRNTTGEHCEKCL----DGYIGDSIRGAPQFCQPCPC 134
           C CNG+++EC   + G   C  CQ NTTG  CE+CL    D         A   C PC C
Sbjct: 271 CKCNGHASECGPDVAGQLAC-RCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC 329

Query: 135 P-LPHLANFAESCYRKNG-AVRC-ICNENYAGPNCERCAPGYY-GNPLLIGSTCKKCDCS 190
                   F    +R  G   RC  C ++ AGP+CERC   +Y  +P +    C+ CDC 
Sbjct: 330 SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRM---PCQPCDCQ 386

Query: 191 GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG--PC 248
                +L    CD+ TG C  C    TG+KC+RC PG++  +        CN  G    C
Sbjct: 387 SAGSLHL---QCDD-TGTCA-CKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTC 441

Query: 249 DSVTGECLEEGFEPPTGCDKC 269
           D  +G C  +       CD+C
Sbjct: 442 DPRSGRCPCKENVEGNLCDRC 462



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 55/178 (30%), Positives = 76/178 (42%), Gaps = 26/178 (14%)

Query: 78  ECVPCDCNGNSNECL---------DGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF 128
           EC+PC+C+G S EC             G C HC+ +T G HCE+C + +     R     
Sbjct: 323 ECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPR---MP 379

Query: 129 CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCD 188
           CQPC C      +    C   +    C C     G  C+RC PG++    L    C+ C 
Sbjct: 380 CQPCDC--QSAGSLHLQC---DDTGTCACKPTVTGWKCDRCLPGFHS---LSEGGCRPCT 431

Query: 189 CSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCGG 245
           C    +P    + CD  +G+C  C  N  G  C+RC PG +         C+ C C G
Sbjct: 432 C----NPAGSLDTCDPRSGRC-PCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYG 484



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 42/134 (31%), Positives = 58/134 (43%), Gaps = 17/134 (12%)

Query: 151 GAVRCICNENYAGPNCERCAPGYYGNPLLIGST-----CKKCDCSGNSDPNLIFEDCDEV 205
           G + C C  N  G +CERC P +   P   G+      C  C+CSG S+      +    
Sbjct: 286 GQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRS 345

Query: 206 T---GQCRNCLRNTTGFKCERCAPGYY-GDARIAKNCAVCNCGGG-----PCDSVTGECL 256
           T   G+C +C  +T G  CERC   +Y  D R+   C  C+C         CD  TG C 
Sbjct: 346 TGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--CQPCDCQSAGSLHLQCDD-TGTCA 402

Query: 257 EEGFEPPTGCDKCV 270
            +       CD+C+
Sbjct: 403 CKPTVTGWKCDRCL 416



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 38/98 (38%), Positives = 46/98 (46%), Gaps = 18/98 (18%)

Query: 155 CICNENYAGPNCERCAPGY-----YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQC 209
           C C   Y G  CE CAPGY      G P    ++C  C C+ +         CD  TG C
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPY---ASCVPCTCNQHG-------TCDPNTGIC 722

Query: 210 RNCLRNTTGFKCERCAPGYYGD--ARIAKNCAVCNCGG 245
             C  +T G  CERC PG+YG+  A  A +C  C C G
Sbjct: 723 -VCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPG 759



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 4/72 (5%)

Query: 65  EKCNAGFFHTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 122
           ++C  GF     G C PC CN  G+ + C   SG C  C+ N  G  C++C  G      
Sbjct: 413 DRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGRC-PCKENVEGNLCDRCRPGTFNLQP 471

Query: 123 RGAPQFCQPCPC 134
              P  C  C C
Sbjct: 472 HN-PAGCSSCFC 482


>gi|157419130 laminin, alpha 4 isoform 3 precursor [Homo sapiens]
          Length = 120

 Score =  135 bits (341), Expect = 3e-31
 Identities = 65/65 (100%), Positives = 65/65 (100%)

Query: 1  MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
          MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
Sbjct: 1  MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60

Query: 61 PPAAE 65
          PPAAE
Sbjct: 61 PPAAE 65


>gi|157419128 laminin, alpha 4 isoform 3 precursor [Homo sapiens]
          Length = 120

 Score =  135 bits (341), Expect = 3e-31
 Identities = 65/65 (100%), Positives = 65/65 (100%)

Query: 1  MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
          MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
Sbjct: 1  MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60

Query: 61 PPAAE 65
          PPAAE
Sbjct: 61 PPAAE 65


>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
          Length = 639

 Score =  132 bits (331), Expect = 4e-30
 Identities = 66/185 (35%), Positives = 92/185 (49%), Gaps = 14/185 (7%)

Query: 57  LGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
           +G +    ++C  G++      C+PC CN  S  C   +G C++CQ N+ G HCE+C +G
Sbjct: 313 VGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEG 372

Query: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNE---NYAGPNCERCAPGY 173
           +       A + C  CPC          SC  K+  +   C++    Y GPNC +C  GY
Sbjct: 373 FYQSP--DATKECLRCPCSA---VTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGY 427

Query: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR 233
           Y       S C+KC C G+ DP    + C   +G+C NCL NTTGF CE C  GY  D  
Sbjct: 428 YN----FDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHD-- 481

Query: 234 IAKNC 238
           +  NC
Sbjct: 482 LEGNC 486



 Score =  105 bits (262), Expect = 4e-22
 Identities = 66/194 (34%), Positives = 85/194 (43%), Gaps = 29/194 (14%)

Query: 82  CDCNG----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
           C+C+     N N C   +G C  C+    G HCE C +G+  +   G    CQPC C  P
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSG---LCQPCDCS-P 295

Query: 138 HLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNL 197
           H A  +  C   N + +C C     G  C+RC  GYYG      + C  C C+  S    
Sbjct: 296 HGA-LSIPC---NSSGKCQCKVGVIGSICDRCQDGYYG---FSKNGCLPCQCNNRS---- 344

Query: 198 IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSV--TGEC 255
               CD +TG C NC  N+ G  CE C  G+Y      K C  C     PC +V  TG C
Sbjct: 345 --ASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRC-----PCSAVTSTGSC 397

Query: 256 LEEGFEPPTGCDKC 269
             +  E    CD+C
Sbjct: 398 SIKSSELEPECDQC 411


>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
          Length = 1193

 Score =  131 bits (329), Expect = 7e-30
 Identities = 174/804 (21%), Positives = 315/804 (39%), Gaps = 138/804 (17%)

Query: 77   GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136
            G C+PC+C G    C   +G C     N   E C  C  G+  D     P+ C+PCPC  
Sbjct: 411  GTCIPCNCQGGG-ACDPDTGDCYSGDENPDIE-CADCPIGFYNDP--HDPRSCKPCPCH- 465

Query: 137  PHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLIGST---CKKCDCSGN 192
                 F+ S   +   V C  C     G  CE CA GY+G+P         C+ C C+ N
Sbjct: 466  ---NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN 522

Query: 193  SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGD---ARIAKNCAVCNC---GGG 246
             DP+    +CD +TG+C  C+ NT G  C++C  GY+GD      A  C  CNC   G  
Sbjct: 523  VDPSAS-GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581

Query: 247  P--CDSVTGECL-EEGFEPPT------GCDKCVWD--------LTDALRLAAL-SIEEGK 288
            P  C S  G C+ + GF  P        C  C           +    R+ AL S  +G 
Sbjct: 582  PVGCRS-DGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGG 640

Query: 289  SGVLSVSSGAAAHRHVNEINATIYLLKTKLSE-RENQYALRKIQINNAENTMKSLLSDVE 347
             GV+  +      +   +    I L   ++SE       L+  ++ + EN+ +S L D++
Sbjct: 641  DGVVPDTELEGRMQQAEQALQDI-LRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLK 699

Query: 348  ELVEK---------------------------ENQAS----------------------R 358
              VE+                           E++AS                      +
Sbjct: 700  MTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQ 759

Query: 359  KGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQK 418
            +   + +  +++ ++  QL  +  D   +   +  K L+ G        + +    L +K
Sbjct: 760  EATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEK 819

Query: 419  MLEEIRSRQPFFTQRELVDEEADEAYE-LLSQAESWQRLHNETRTLFPVVLEQLDDYNAK 477
            + +     Q    +    + EAD +Y+  L   +S  RL   +   F V  E+      K
Sbjct: 820  LEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQV--EEAKRIKQK 877

Query: 478  LSDLQEALDQALN-YVRDAEDM-NRATAARQ--RDHEKQQERVREQMEVVNMSLSTSADS 533
               L   + + ++ + R  +++ N    A+Q  ++ +  +E+  + +   N++ S + ++
Sbjct: 878  ADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEA 937

Query: 534  LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 593
            L+    T  E++ I+KN      ++D  K+E +  +  LS +S   V +A D  Q  ++ 
Sbjct: 938  LSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQK-VSDASDKTQQAERA 996

Query: 594  ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGI-- 651
                +     +  NG  +    +S + + I +   EAN TA+ AL     +    S +  
Sbjct: 997  LGSAAADAQRA-KNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMRE 1055

Query: 652  --------DTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGAL-------- 695
                    + +   + D  + ++ +A+++  +A+++    + DT   + G L        
Sbjct: 1056 VEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNAG-VTIQDTLNTLDGLLHLMDQPLS 1114

Query: 696  ----------ARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQAT 745
                       + S  KT+++  ++ + +     A+Q+ G   L+    +    +V+   
Sbjct: 1115 VDEEGLVLLEQKLSRAKTQINSQLRPMMSELEERARQQRGHLHLLETSIDGILADVK--- 1171

Query: 746  APMANNLTNWSQNLQHFDSSAYNT 769
                 NL N   NL       YNT
Sbjct: 1172 -----NLENIRDNL---PPGCYNT 1187



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 62/182 (34%), Positives = 82/182 (45%), Gaps = 36/182 (19%)

Query: 82  CDCNGNSNECL--------DGSGY-CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPC 132
           CDCNG S +C+         G+G+ C++C  NT G HCEKC +G+     R     C PC
Sbjct: 28  CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR---CLPC 84

Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC-------- 184
            C      +      R + + RC C     G  C+RC PG++   +L  + C        
Sbjct: 85  NC-----NSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH---MLTDAGCTQDQRLLD 136

Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNC 243
            KCDC    DP  I   CD   G+C  C    TG +C+RC  GYY  D    + C  C C
Sbjct: 137 SKCDC----DPAGIAGPCD--AGRC-VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189

Query: 244 GG 245
            G
Sbjct: 190 YG 191



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 49/140 (35%), Positives = 63/140 (45%), Gaps = 23/140 (16%)

Query: 65  EKCNAGFF-HTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
           EKC  GF+ H     C+PC+CN  G+ +   D SG C  C+   TG  C++CL G+   +
Sbjct: 66  EKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRC-SCKPGVTGARCDRCLPGFHMLT 124

Query: 122 IRGAPQ----FCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY--- 174
             G  Q        C C     A  A  C     A RC+C     G  C+RC  GYY   
Sbjct: 125 DAGCTQDQRLLDSKCDC---DPAGIAGPC----DAGRCVCKPAVTGERCDRCRSGYYNLD 177

Query: 175 -GNPLLIGSTCKKCDCSGNS 193
            GNP      C +C C G+S
Sbjct: 178 GGNP----EGCTQCFCYGHS 193



 Score = 71.2 bits (173), Expect = 8e-12
 Identities = 147/690 (21%), Positives = 246/690 (35%), Gaps = 147/690 (21%)

Query: 154  RCICNENYAGPNCERCAPGYYGNPLLIG--STCKKCDC--------------SGNSDPNL 197
            +CIC   Y G  C+ CA GY  +   +G   TC  C+C              SG+ +P++
Sbjct: 381  QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440

Query: 198  IFEDC-------------------------------DEVTGQCRNCLRNTTGFKCERCAP 226
               DC                               +EV   C NC    TG +CE CA 
Sbjct: 441  ECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV--CNNCPPGVTGARCELCAD 498

Query: 227  GYYGDA----RIAKNCAVCNC-------GGGPCDSVTGECL--------------EEGF- 260
            GY+GD        + C  C C         G CD +TG CL              + G+ 
Sbjct: 499  GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558

Query: 261  -EP--PTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTK 317
             +P  P   DKC     + +    +      + V     G     H        Y     
Sbjct: 559  GDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAFSCPACY----- 613

Query: 318  LSERENQYALRKIQINNAENTMKSLLSDVE--ELVEKENQASRKGQLVQKESMDTINHAS 375
                 NQ  ++  Q       M++L+S  +  + V  + +   + Q  ++   D +  A 
Sbjct: 614  -----NQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQ 668

Query: 376  QLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQREL 435
                 +  +  ++ ++ ++   Y    +     +     L  +    +R      TQ + 
Sbjct: 669  ISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQ- 727

Query: 436  VDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDY---NAKLSDLQEALDQALNYV 492
                       LS AES   L N         +   D Y   N   S  QEA   A ++V
Sbjct: 728  -----------LSLAESEASLGNTN-------IPASDHYVGPNGFKSLAQEATRLAESHV 769

Query: 493  RDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRL------TLSELDD 546
              A +M + T   +   ++    VR+ +     S S S D      L      T S    
Sbjct: 770  ESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQ 829

Query: 547  IIKNASGIYAEIDGAKS-----ELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRKL 601
            + + A+   AEI+  +S      L   +S L  +S    Q  ++ A+ ++Q+A+ LS  +
Sbjct: 830  LTREAT--QAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQ--VEEAKRIKQKADSLSSLV 885

Query: 602  -HSSDMNGLVQKAL-----DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQI 655
                D     QK L     +A  + +N  +   ++++    A     R  +A+S +    
Sbjct: 886  TRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALS-MGNAT 944

Query: 656  IYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAA 715
             Y   E E++L   RE   + ++   EA          A+ R S +  ++SDA  + Q A
Sbjct: 945  FY---EVESILKNLREFDLQVDNRKAEAEE--------AMKRLSYISQKVSDASDKTQQA 993

Query: 716  ER--GDAQQRLGQSRLITEEANRTTMEVQQ 743
            ER  G A     +++    EA   + E++Q
Sbjct: 994  ERALGSAAADAQRAKNGAGEALEISSEIEQ 1023



 Score = 31.2 bits (69), Expect = 9.6
 Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 7/65 (10%)

Query: 65  EKCNAGFFHTLSGE---CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
           ++C +G+++   G    C  C C G+S  C   + Y VH   +T  +     +DG+    
Sbjct: 167 DRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQD----VDGWKAVQ 222

Query: 122 IRGAP 126
             G+P
Sbjct: 223 RNGSP 227


>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
          Length = 1111

 Score =  129 bits (325), Expect = 2e-29
 Identities = 150/645 (23%), Positives = 259/645 (40%), Gaps = 98/645 (15%)

Query: 77   GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136
            G C+PC+C G    C   +G C     N   E C  C  G+  D     P+ C+PCPC  
Sbjct: 411  GTCIPCNCQGGG-ACDPDTGDCYSGDENPDIE-CADCPIGFYNDP--HDPRSCKPCPCH- 465

Query: 137  PHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLIGST---CKKCDCSGN 192
                 F+ S   +   V C  C     G  CE CA GY+G+P         C+ C C+ N
Sbjct: 466  ---NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN 522

Query: 193  SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGD---ARIAKNCAVCNC---GGG 246
             DP+    +CD +TG+C  C+ NT G  C++C  GY+GD      A  C  CNC   G  
Sbjct: 523  VDPSAS-GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581

Query: 247  P--CDSVTGECL-EEGFEPPT------GCDKCVWD--------LTDALRLAAL-SIEEGK 288
            P  C S  G C+ + GF  P        C  C           +    R+ AL S  +G 
Sbjct: 582  PVGCRS-DGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGG 640

Query: 289  SGVLSVSSGAAAHRHVNEINATIYLLKTKLSE-RENQYALRKIQINNAENTMKSLLSDVE 347
             GV+  +      +   +    I L   ++SE       L+  ++ + EN+ +S L D++
Sbjct: 641  DGVVPDTELEGRMQQAEQALQDI-LRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLK 699

Query: 348  ELVEK---------------------------ENQAS----------------------R 358
              VE+                           E++AS                      +
Sbjct: 700  MTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQ 759

Query: 359  KGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQK 418
            +   + +  +++ ++  QL  +  D   +   +  K L+ G        + +    L +K
Sbjct: 760  EATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEK 819

Query: 419  MLEEIRSRQPFFTQRELVDEEADEAYE-LLSQAESWQRLHNETRTLFPVVLEQLDDYNAK 477
            + +     Q    +    + EAD +Y+  L   +S  RL   +   F V  E+      K
Sbjct: 820  LEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQV--EEAKRIKQK 877

Query: 478  LSDLQEALDQALN-YVRDAEDM-NRATAARQ--RDHEKQQERVREQMEVVNMSLSTSADS 533
               L   + + ++ + R  +++ N    A+Q  ++ +  +E+  + +   N++ S + ++
Sbjct: 878  ADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEA 937

Query: 534  LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 593
            L+    T  E++ I+KN      ++D  K+E +  +  LS +S   V +A D  Q  ++ 
Sbjct: 938  LSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQK-VSDASDKTQQAERA 996

Query: 594  ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFAL 638
                +     +  NG  +    +S + + I +   EAN TA+ AL
Sbjct: 997  LGSAAADAQRA-KNGAGEALEISSEIEQEIGSLNLEANVTADGAL 1040



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 62/182 (34%), Positives = 82/182 (45%), Gaps = 36/182 (19%)

Query: 82  CDCNGNSNECL--------DGSGY-CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPC 132
           CDCNG S +C+         G+G+ C++C  NT G HCEKC +G+     R     C PC
Sbjct: 28  CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR---CLPC 84

Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC-------- 184
            C      +      R + + RC C     G  C+RC PG++   +L  + C        
Sbjct: 85  NC-----NSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH---MLTDAGCTQDQRLLD 136

Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNC 243
            KCDC    DP  I   CD   G+C  C    TG +C+RC  GYY  D    + C  C C
Sbjct: 137 SKCDC----DPAGIAGPCD--AGRC-VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189

Query: 244 GG 245
            G
Sbjct: 190 YG 191



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 49/140 (35%), Positives = 63/140 (45%), Gaps = 23/140 (16%)

Query: 65  EKCNAGFF-HTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
           EKC  GF+ H     C+PC+CN  G+ +   D SG C  C+   TG  C++CL G+   +
Sbjct: 66  EKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRC-SCKPGVTGARCDRCLPGFHMLT 124

Query: 122 IRGAPQ----FCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY--- 174
             G  Q        C C     A  A  C     A RC+C     G  C+RC  GYY   
Sbjct: 125 DAGCTQDQRLLDSKCDC---DPAGIAGPC----DAGRCVCKPAVTGERCDRCRSGYYNLD 177

Query: 175 -GNPLLIGSTCKKCDCSGNS 193
            GNP      C +C C G+S
Sbjct: 178 GGNP----EGCTQCFCYGHS 193



 Score = 71.2 bits (173), Expect = 8e-12
 Identities = 147/690 (21%), Positives = 246/690 (35%), Gaps = 147/690 (21%)

Query: 154  RCICNENYAGPNCERCAPGYYGNPLLIG--STCKKCDC--------------SGNSDPNL 197
            +CIC   Y G  C+ CA GY  +   +G   TC  C+C              SG+ +P++
Sbjct: 381  QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440

Query: 198  IFEDC-------------------------------DEVTGQCRNCLRNTTGFKCERCAP 226
               DC                               +EV   C NC    TG +CE CA 
Sbjct: 441  ECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV--CNNCPPGVTGARCELCAD 498

Query: 227  GYYGDA----RIAKNCAVCNC-------GGGPCDSVTGECL--------------EEGF- 260
            GY+GD        + C  C C         G CD +TG CL              + G+ 
Sbjct: 499  GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558

Query: 261  -EP--PTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTK 317
             +P  P   DKC     + +    +      + V     G     H        Y     
Sbjct: 559  GDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAFSCPACY----- 613

Query: 318  LSERENQYALRKIQINNAENTMKSLLSDVE--ELVEKENQASRKGQLVQKESMDTINHAS 375
                 NQ  ++  Q       M++L+S  +  + V  + +   + Q  ++   D +  A 
Sbjct: 614  -----NQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQ 668

Query: 376  QLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQREL 435
                 +  +  ++ ++ ++   Y    +     +     L  +    +R      TQ + 
Sbjct: 669  ISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQ- 727

Query: 436  VDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDY---NAKLSDLQEALDQALNYV 492
                       LS AES   L N         +   D Y   N   S  QEA   A ++V
Sbjct: 728  -----------LSLAESEASLGNTN-------IPASDHYVGPNGFKSLAQEATRLAESHV 769

Query: 493  RDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRL------TLSELDD 546
              A +M + T   +   ++    VR+ +     S S S D      L      T S    
Sbjct: 770  ESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQ 829

Query: 547  IIKNASGIYAEIDGAKS-----ELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRKL 601
            + + A+   AEI+  +S      L   +S L  +S    Q  ++ A+ ++Q+A+ LS  +
Sbjct: 830  LTREAT--QAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQ--VEEAKRIKQKADSLSSLV 885

Query: 602  -HSSDMNGLVQKAL-----DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQI 655
                D     QK L     +A  + +N  +   ++++    A     R  +A+S +    
Sbjct: 886  TRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALS-MGNAT 944

Query: 656  IYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAA 715
             Y   E E++L   RE   + ++   EA          A+ R S +  ++SDA  + Q A
Sbjct: 945  FY---EVESILKNLREFDLQVDNRKAEAEE--------AMKRLSYISQKVSDASDKTQQA 993

Query: 716  ER--GDAQQRLGQSRLITEEANRTTMEVQQ 743
            ER  G A     +++    EA   + E++Q
Sbjct: 994  ERALGSAAADAQRAKNGAGEALEISSEIEQ 1023



 Score = 31.2 bits (69), Expect = 9.6
 Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 7/65 (10%)

Query: 65  EKCNAGFFHTLSGE---CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
           ++C +G+++   G    C  C C G+S  C   + Y VH   +T  +     +DG+    
Sbjct: 167 DRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQD----VDGWKAVQ 222

Query: 122 IRGAP 126
             G+P
Sbjct: 223 RNGSP 227


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score =  128 bits (321), Expect = 6e-29
 Identities = 82/264 (31%), Positives = 117/264 (44%), Gaps = 30/264 (11%)

Query: 15   LLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHT 74
            L+ ++   + A    +    D+      G+    E  +     G   P+ + C+ G+  T
Sbjct: 1088 LIRASYAQQPAESRVSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRT 1147

Query: 75   LSG----ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQ 130
             SG     C  C C+G+S  C   +G C  CQ +T G  CE+C  GY GD+ RG PQ CQ
Sbjct: 1148 PSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQ 1207

Query: 131  PCPC-PLPHLANFAESCY-RKNGAVRC-ICNENYAGPNCERCAPGYYGNPLLIGSTCKK- 186
             CPC   P     A +C+   +G   C  C+  ++G +CERCAPGYYGNP   G  C++ 
Sbjct: 1208 LCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQ-GQPCQRD 1266

Query: 187  --------CDCSGNSDP-NLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAK 236
                    C+C    DP   +   CD   GQC+ C     G  C  C P ++   A    
Sbjct: 1267 SQVPGPIGCNC----DPQGSVSSQCD-AAGQCQ-CKAQVEGLTCSHCRPHHFHLSASNPD 1320

Query: 237  NCAVCNCGGGPCDSVTGECLEEGF 260
             C  C C G     +T +C    +
Sbjct: 1321 GCLPCFCMG-----ITQQCASSAY 1339



 Score =  125 bits (314), Expect = 4e-28
 Identities = 74/230 (32%), Positives = 105/230 (45%), Gaps = 23/230 (10%)

Query: 29  DNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSGE----CVPCDC 84
           D A    +  +++ GR    E  E R  +G    + E C+A F     G     C  C+C
Sbjct: 709 DIAMDTTVTHATSHGRAHSVE--ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNC 766

Query: 85  NGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP-LPHLANFA 143
           NG+++ C    G+C++CQ NT G  C KC  G+ GD+++     C+PCPCP +     F+
Sbjct: 767 NGHASSCDPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFS 826

Query: 144 ESCY-RKNGAVRC-ICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFED 201
           ++C+   +G   C  C   Y G  CE CAPGY GNP+  G  C+          N     
Sbjct: 827 DTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPV--------NQEIVR 878

Query: 202 CDE-----VTGQCRNCLRNTTGFKCERCAPG-YYGDARIAKNCAVCNCGG 245
           CDE      +G+   C  N  G  C  CA G ++   R    C  C C G
Sbjct: 879 CDERGSMGTSGEACRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCMG 928



 Score =  117 bits (292), Expect = 1e-25
 Identities = 59/143 (41%), Positives = 74/143 (51%), Gaps = 7/143 (4%)

Query: 49   ETSEPRVALGRLPPAAEKCNAGFFHTLSG----ECVPCDCNGNSNECLDGSGYCVHCQRN 104
            E  E R   G +  + + C  G+  T SG     C  C+CNG+S+ C   +G C  CQ N
Sbjct: 1526 EVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHN 1585

Query: 105  TTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLAN-FAESCYRKN-GAVRC-ICNENY 161
              GE CE C  GY GD+  G P+ CQPC CPL +  N F+ +C     G  RC  C   Y
Sbjct: 1586 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGY 1645

Query: 162  AGPNCERCAPGYYGNPLLIGSTC 184
             G  CE+C PGY GNP + G  C
Sbjct: 1646 TGQYCEQCGPGYVGNPSVQGGQC 1668



 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 40/93 (43%), Positives = 50/93 (53%), Gaps = 11/93 (11%)

Query: 155  CICNENYAGPNCERCAPGYY--GNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNC 212
            C C   Y G +C+ CAPGY   G+ L +G  C+ C+C+G+SD       C   TG C  C
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGH-CELCECNGHSDL------CHPETGACSQC 1582

Query: 213  LRNTTGFKCERCAPGYYGDARIA--KNCAVCNC 243
              N  G  CE CAPGYYGDA     ++C  C C
Sbjct: 1583 QHNAAGEFCELCAPGYYGDATAGTPEDCQPCAC 1615



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 41/138 (29%), Positives = 57/138 (41%), Gaps = 10/138 (7%)

Query: 101  CQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNEN 160
            C     G  C+ C  GY           C+ C C        ++ C+ + GA    C  N
Sbjct: 1532 CPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN-----GHSDLCHPETGACSQ-CQHN 1585

Query: 161  YAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDCDEVTG---QCRNCLRNT 216
             AG  CE CAPGYYG+        C+ C C   +  N+    C+ +     +C  C    
Sbjct: 1586 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGY 1645

Query: 217  TGFKCERCAPGYYGDARI 234
            TG  CE+C PGY G+  +
Sbjct: 1646 TGQYCEQCGPGYVGNPSV 1663



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 36/135 (26%), Positives = 68/135 (50%), Gaps = 7/135 (5%)

Query: 1490 IRLRTRSSHGMIFYVSDQ-----EENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDG 1544
            + +RT ++ G++ +   +     +  DF++L L  G LV+ + +G  + ++ S++  NDG
Sbjct: 4232 LEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEARLVSEDPINDG 4291

Query: 1545 LWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSI 1604
             WH V  +RE   G + +DG  ++    P        KG +Y+GG      +   + +S 
Sbjct: 4292 EWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSS- 4350

Query: 1605 YSFSGCLSNLQLNGA 1619
               +GC+ NL L+ A
Sbjct: 4351 -GITGCVKNLVLHSA 4364



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 39/149 (26%), Positives = 60/149 (40%), Gaps = 10/149 (6%)

Query: 1511 DFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEE 1570
            DF++L +  G L + + +G     +RS E    G WH V   R    G L ++G R +  
Sbjct: 3978 DFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGRWHRVSAERLNKDGSLRVNGGRPVLR 4037

Query: 1571 SLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASI--------- 1621
            S P       +   +YLGGV P   + +   N    F GC+  + +NG  +         
Sbjct: 4038 SSPGKSQGLNLHTLLYLGGVEPSVPL-SPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGS 4096

Query: 1622 TSASQTFSVTPCFEGPMETGTYFSTEGGY 1650
                Q +  +PC   P + G      G Y
Sbjct: 4097 QGIGQCYDSSPCERQPCQHGATCMPAGEY 4125



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 40/169 (23%), Positives = 79/169 (46%), Gaps = 16/169 (9%)

Query: 1635 EGPMETGTYFSTEGGYVVLDESFNIGLKF---EIAFEVRPRSSSGTLVH-----GHSVNG 1686
            + P + G YF  +G        F+  L      I  EVR  ++SG L+      G +  G
Sbjct: 4197 DAPGQYGAYFHDDGFLAFPGHVFSRSLPEVPETIELEVRTSTASGLLLWQGVEVGEAGQG 4256

Query: 1687 -EYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVN 1745
             +++++ +++G ++ +   G  +    +  +  + DG WHR+T +R+     + VD E  
Sbjct: 4257 KDFISLGLQDGHLVFRYQLGSGE--ARLVSEDPINDGEWHRVTALREGRRGSIQVDGE-- 4312

Query: 1746 HVVGPLNPKP---IDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVI 1791
             +V   +P P   ++ +  V++GG P+         S   TGC+++ V+
Sbjct: 4313 ELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNLVL 4361



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 35/148 (23%), Positives = 59/148 (39%), Gaps = 13/148 (8%)

Query: 1485 KSQFSIRLRTRSSHGMIFYVSDQE-----------ENDFMTLFLAHGRLVYMFNVGHKKL 1533
            K +  I  R  S+ GM+ Y   +            + DF++  L  GR  + F+ G    
Sbjct: 3685 KFEIKITFRPDSADGMLLYNGQKRVPGSPTNLANRQPDFISFGLVGGRPEFRFDAGSGMA 3744

Query: 1534 KIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPG 1593
             IR       G +H V  +R  + G L++  L  +  +         +   +YLGG    
Sbjct: 3745 TIRHPTPLALGHFHTVTLLRSLTQGSLIVGDLAPVNGTSQGKFQGLDLNEELYLGGYPDY 3804

Query: 1594 KAVKNVQINSIYSFSGCLSNLQLNGASI 1621
             A+    ++S   F GC+  L++ G  I
Sbjct: 3805 GAIPKAGLSS--GFIGCVRELRIQGEEI 3830



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 42/174 (24%), Positives = 70/174 (40%), Gaps = 33/174 (18%)

Query: 1662 KFEIAFEVRPRSSSGTLVH-------GHSVN-----GEYLNVHMKNGQVIVKVNNGIRDF 1709
            KFEI    RP S+ G L++       G   N      ++++  +  G+   + + G    
Sbjct: 3685 KFEIKITFRPDSADGMLLYNGQKRVPGSPTNLANRQPDFISFGLVGGRPEFRFDAG--SG 3742

Query: 1710 STSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNP---------KPIDHRE 1760
              ++     L  G +H +T++R      L        +VG L P         + +D  E
Sbjct: 3743 MATIRHPTPLALGHFHTVTLLRSLTQGSL--------IVGDLAPVNGTSQGKFQGLDLNE 3794

Query: 1761 PVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSCP 1814
             +++GG P+    P+   S  F GC+R   I G  + F    L   A  I+ CP
Sbjct: 3795 ELYLGGYPDYGAIPKAGLSSGFIGCVRELRIQGEEIVFHDLNLT--AHGISHCP 3846



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 44/190 (23%), Positives = 77/190 (40%), Gaps = 17/190 (8%)

Query: 1633 CFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNG---EYL 1689
            C EG   T    S  G Y+ L    N   +  +  E +P +  G L+     +G   +++
Sbjct: 3921 CEEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLAPDGVLLFSGGKSGPVEDFV 3980

Query: 1690 NVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVG 1749
            ++ M  G +  +   G       +   + L  GRWHR++  R    +  D    VN    
Sbjct: 3981 SLAMVGGHLEFRYELG--SGLAVLRSAEPLALGRWHRVSAER----LNKDGSLRVNGGRP 4034

Query: 1750 PLNPKP-----IDHREPVFVGGVPESL-LTPRLAPSKPFTGCIRHFVIDGHPVSFSKAAL 1803
             L   P     ++    +++GGV  S+ L+P    S  F GC+    ++G  +  + + L
Sbjct: 4035 VLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFL 4094

Query: 1804 VSGAVSINSC 1813
              G+  I  C
Sbjct: 4095 --GSQGIGQC 4102



 Score = 35.0 bits (79), Expect = 0.67
 Identities = 31/89 (34%), Positives = 38/89 (42%), Gaps = 21/89 (23%)

Query: 208 QCRNCLRNTTGFKCERC------APG--YYGDARIAKNCAVCNCGG--GPCDSVTGECL- 256
           +CR C    +G  CE C       PG  Y G       C+ CNC G    CD V G CL 
Sbjct: 730 ECR-CPIGYSGLSCESCDAHFTRVPGGPYLG------TCSGCNCNGHASSCDPVYGHCLN 782

Query: 257 -EEGFEPPTGCDKC-VWDLTDALRLAALS 283
            +   E P  C+KC      DA++  A S
Sbjct: 783 CQHNTEGPQ-CNKCKAGFFGDAMKATATS 810



 Score = 31.6 bits (70), Expect = 7.4
 Identities = 41/188 (21%), Positives = 70/188 (37%), Gaps = 21/188 (11%)

Query: 834  QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK 893
            +  V   ++T    L   T    Y K  +K     ++AD  +LY G K        LA +
Sbjct: 3660 ERVVPYFTQTPYSFLPLPTIKDAYRKFEIKITFRPDSADGMLLYNGQKRVPGSPTNLANR 3719

Query: 894  NDNLVYVYNLGTKDVEIPLDS--------KPVSSWPAYFSIVKIERVGKHGKVFLTVPSL 945
              + +    +G +  E   D+         P      +F  V + R    G + +     
Sbjct: 3720 QPDFISFGLVGGRP-EFRFDAGSGMATIRHPTPLALGHFHTVTLLRSLTQGSLIV----- 3773

Query: 946  SSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLN 1005
               A      +G+F G    LDL+ E    Y+GG P    +P +    GF+GC+    + 
Sbjct: 3774 GDLAPVNGTSQGKFQG----LDLNEE---LYLGGYPDYGAIPKAGLSSGFIGCVRELRIQ 3826

Query: 1006 NDVISLYN 1013
             + I  ++
Sbjct: 3827 GEEIVFHD 3834


>gi|219842266 usherin isoform B [Homo sapiens]
          Length = 5202

 Score =  106 bits (265), Expect = 2e-22
 Identities = 85/357 (23%), Positives = 168/357 (47%), Gaps = 40/357 (11%)

Query: 1483 GAKSQFSIRLRTRSSHGMI-FYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQ--- 1538
            G K+ F    RT+   G+I F  S   + ++  L L  GRL ++F+     +++ +    
Sbjct: 1543 GIKASF----RTKVPEGLIVFAASPGNQEEYFALQLKKGRLYFLFDPQGSPVEVTTTNDH 1598

Query: 1539 -EKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVK 1597
             ++Y+DG WH++I IR ++ G++ +DG+     ++            ++LGG+     + 
Sbjct: 1599 GKQYSDGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVIGDNTGVFLGGLPRSYTIL 1658

Query: 1598 NVQINSIY-SFSGCLSNLQL----NGASI------TSASQTFSVTPCFEG---PMETGTY 1643
                  I   F GCL ++      N ++I       S+ +  +V   +EG    +  G  
Sbjct: 1659 RKDPEIIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQINVYNSWEGCPASLNEGAQ 1718

Query: 1644 FSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNG-EYLNVHMKNGQVIVKV 1702
            F   G   +    F+ G+ FEI+F+ R    +G L+  ++ +G ++L + +K+G +  ++
Sbjct: 1719 FLGAGFLELHPYMFHGGMNFEISFKFRTDQLNGLLLFVYNKDGPDFLAMELKSGILTFRL 1778

Query: 1703 NNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPV 1762
            N  +      +    S C+G+W+++ + ++ + +   V+  + H       +P+    PV
Sbjct: 1779 NTSLAFTQVDLLLGLSYCNGKWNKVIIKKEGSFISASVNGLMKH-ASESGDQPLVVNSPV 1837

Query: 1763 FVGGVPESLLT--PRLAPSKPFTGCIRHFVIDGHPVSFSKAALV------SGAVSIN 1811
            +VGG+P+ LL     L   + F GC++        V F++ A+V      SGAV +N
Sbjct: 1838 YVGGIPQELLNSYQHLCLEQGFGGCMK-------DVKFTRGAVVNLASVSSGAVRVN 1887



 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 61/219 (27%), Positives = 88/219 (40%), Gaps = 38/219 (17%)

Query: 79  CVPCDCNGNSNEC--------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGD--SI 122
           C PC CN +S  C                G G C  C+ NTTG +CE C D +     + 
Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631

Query: 123 RGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGS 182
             A   C+PC C      N +  C +  G  +C C  + +G  C +C  G+Y    L   
Sbjct: 632 PSAIDVCKPCDCDTVGTRNGSILCDQIGG--QCNCKRHVSGRQCNQCQNGFYNLQELDPD 689

Query: 183 TCKKCDC--SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGY-----YGDARIA 235
            C  C+C  SG  D ++    C + +GQC+ C  N  G +C+ C  G+     + D    
Sbjct: 690 GCSPCNCNTSGTVDGDI---TCHQNSGQCK-CKANVIGLRCDHCNFGFKFLRSFNDV--- 742

Query: 236 KNCAVCNCG-----GGPCDSVTGECLEEGFEPPTGCDKC 269
             C  C C         C+  +G+C  +       CD C
Sbjct: 743 -GCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTC 780



 Score = 87.8 bits (216), Expect = 9e-17
 Identities = 66/230 (28%), Positives = 98/230 (42%), Gaps = 47/230 (20%)

Query: 74  TLSGECVPCDCNGNSNEC-LDGSGYCVHCQRN--TTGEHCEKCLDGYIGDSIRGAPQF-- 128
           T+SG C    C+G+++ C      Y   C +   T G HC++CL  Y     R   Q   
Sbjct: 513 TISGRC---QCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569

Query: 129 --CQPCPCPLPHLANFAESC-------------YRKNGAVRCICNENYAGPNCERCAPGY 173
             C+PC C      + ++SC             +R  G V   C  N  G NCE C   +
Sbjct: 570 FNCKPCQC-----NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYF 624

Query: 174 Y----GNPLLIGSTCKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG 227
           +     +P  I   CK CDC   G  + +++   CD++ GQC NC R+ +G +C +C  G
Sbjct: 625 FRQVGADPSAI-DVCKPCDCDTVGTRNGSIL---CDQIGGQC-NCKRHVSGRQCNQCQNG 679

Query: 228 YYGDARI-AKNCAVCNC-------GGGPCDSVTGECLEEGFEPPTGCDKC 269
           +Y    +    C+ CNC       G   C   +G+C  +       CD C
Sbjct: 680 FYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHC 729



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 65/224 (29%), Positives = 95/224 (42%), Gaps = 35/224 (15%)

Query: 65  EKCNAGFFHTLSGE---CVPCDCN--GNSNE-CLDGSGYCVHCQRNTTGEHCEKCLDGYI 118
           + CN GF    S     C PC CN  G+ N+ C   SG C  C++   G  C+ C + + 
Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAKGLQCDTCRENFY 785

Query: 119 GDSIRGAPQFCQPCPC----PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
           G  +      C+ C C     LP        C  K G  +CIC  N  G  C +C  G +
Sbjct: 786 GLDVTN----CKACDCDTAGSLP-----GTVCNAKTG--QCICKPNVEGRQCNKCLEGNF 834

Query: 175 GNPLLIGSTCKKCDC--SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-D 231
                    C  C+C  +G  + +L+   C++ TGQC  C    TG +C +C P  Y   
Sbjct: 835 YLRQNNSFLCLPCNCDKTGTINGSLL---CNKSTGQC-PCKLGVTGLRCNQCEPHRYNLT 890

Query: 232 ARIAKNCAVCNCG------GGPCDSVTGECLEEGFEPPTGCDKC 269
               ++C +C C       G  CD ++G+CL         C++C
Sbjct: 891 IDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQC 934



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 66/222 (29%), Positives = 91/222 (40%), Gaps = 30/222 (13%)

Query: 66   KCNAGFFHTLSGE---CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117
            KC  G F+        C+PC+C+       S  C   +G C  C+   TG  C +C    
Sbjct: 828  KCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCP-CKLGVTGLRCNQCEPHR 886

Query: 118  IGDSIRGAPQFCQPCPCP----LPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGY 173
               +I    Q CQ C C     LP        C   +G  +C+C  N  G  C +C PG+
Sbjct: 887  YNLTIDNF-QHCQMCECDSLGTLP-----GTICDPISG--QCLCVPNRQGRRCNQCQPGF 938

Query: 174  YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR 233
            Y +P    + C  C C      N I   C+ +TGQC     +  G +C++C   Y+G   
Sbjct: 939  YISPGN-ATGCLPCSCHTTGAVNHI---CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDP 994

Query: 234  IAKNCAVCNCG-----GGPCDSVTGECLEEGFEPPTGCDKCV 270
                C  CNC         C  VTG+C  + F   + CD CV
Sbjct: 995  QTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 48/153 (31%), Positives = 65/153 (42%), Gaps = 17/153 (11%)

Query: 79   CVPCDCNG----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPC 134
            C  C+C+         C   SG C+ C  N  G  C +C  G+      G    C PC C
Sbjct: 897  CQMCECDSLGTLPGTICDPISGQCL-CVPNRQGRRCNQCQPGFYISP--GNATGCLPCSC 953

Query: 135  PLPHLANFAESCYRKNGAVRCICNE-NYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNS 193
                  N    C    G  +C+C + + AG  C++C   Y+G     G  C+ C+C  + 
Sbjct: 954  HTTGAVNHI--CNSLTG--QCVCQDASIAGQRCDQCKDHYFGFDPQTGR-CQPCNCHLSG 1008

Query: 194  DPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226
              N   E C  VTGQC  C +  TG KC+ C P
Sbjct: 1009 ALN---ETCHLVTGQCF-CKQFVTGSKCDACVP 1037



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 35/112 (31%), Positives = 52/112 (46%), Gaps = 13/112 (11%)

Query: 66   KCNAGFFHTLSGE--CVPCDCNGN---SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG- 119
            +C  GF+ +      C+PC C+     ++ C   +G CV    +  G+ C++C D Y G 
Sbjct: 933  QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992

Query: 120  DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAP 171
            D   G    CQPC C L    N  E+C+   G  +C C +   G  C+ C P
Sbjct: 993  DPQTGR---CQPCNCHLSGALN--ETCHLVTG--QCFCKQFVTGSKCDACVP 1037



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 74/269 (27%), Positives = 103/269 (38%), Gaps = 49/269 (18%)

Query: 1045 FDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMV---NGSMFFRLEMRNGYLH 1101
            F G+GY      T        T      RT    GLI+      N   +F L+++ G L+
Sbjct: 1522 FIGNGYCKFPSSTHPVNT-DFTGIKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLY 1580

Query: 1102 VFYDFGFSGGPVHLEDTLKKA-QINDAKYHEISIIYHNDKKMILVVDRRHVKS---MDNE 1157
              +D    G PV +  T     Q +D K+HEI  I H     I  +D  +  S   ++  
Sbjct: 1581 FLFDP--QGSPVEVTTTNDHGKQYSDGKWHEIIAIRHQAFGQI-TLDGIYTGSSAILNGS 1637

Query: 1158 KMKIPFTDIYIGGAP---------PEILQSRALRAHLPLDINFRGCMKGFQFQKK----- 1203
             +    T +++GG P         PEI+Q             F GC+K   F K      
Sbjct: 1638 TVIGDNTGVFLGGLPRSYTILRKDPEIIQK-----------GFVGCLKDVHFMKNYNPSA 1686

Query: 1204 -----DFNLLE-QTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDG--FEGGFN 1255
                 D+   E Q        GCP    ++  A F G  F+  +    F  G  FE  F 
Sbjct: 1687 IWEPLDWQSSEEQINVYNSWEGCPAS--LNEGAQFLGAGFL-ELHPYMFHGGMNFEISFK 1743

Query: 1256 FRTLQPNGLLF--YYASGSDVFSISLDNG 1282
            FRT Q NGLL   Y   G D  ++ L +G
Sbjct: 1744 FRTDQLNGLLLFVYNKDGPDFLAMELKSG 1772



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 70/356 (19%), Positives = 144/356 (40%), Gaps = 44/356 (12%)

Query: 862  VKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWP 921
            +K    T+  +  I++  S   ++EY  L +K   L ++++                   
Sbjct: 1544 IKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLYFLFD------------------- 1584

Query: 922  AYFSIVKIERVGKHGKVFL-----TVPSLSSTAEEKFIKKGEFSGDDSLLD---LDPEDT 973
               S V++     HGK +       + ++   A  +    G ++G  ++L+   +  ++T
Sbjct: 1585 PQGSPVEVTTTNDHGKQYSDGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVIGDNT 1644

Query: 974  VFYVGGVPSNFKL---PTSLNLPGFVGCLELATL--NNDVISLYNFKHIYNMDPSTSVPC 1028
              ++GG+P ++ +      +   GFVGCL+      N +  +++      + +   +V  
Sbjct: 1645 GVFLGGLPRSYTILRKDPEIIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQINVYN 1704

Query: 1029 ARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVN-- 1086
            + +    + +  A +   G+G+  +      G  G       + RT   NGL+L + N  
Sbjct: 1705 SWEGCPASLNEGAQFL--GAGFLELHPYMFHG--GMNFEISFKFRTDQLNGLLLFVYNKD 1760

Query: 1087 GSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVV 1146
            G  F  +E+++G L    +   +   V   D L      + K++++ I          V 
Sbjct: 1761 GPDFLAMELKSGILTFRLNTSLAFTQV---DLLLGLSYCNGKWNKVIIKKEGSFISASVN 1817

Query: 1147 DRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQK 1202
                  S   ++  +  + +Y+GG P E+L S     HL L+  F GCMK  +F +
Sbjct: 1818 GLMKHASESGDQPLVVNSPVYVGGIPQELLNS---YQHLCLEQGFGGCMKDVKFTR 1870


>gi|93204871 netrin 4 [Homo sapiens]
          Length = 628

 Score =  102 bits (255), Expect = 3e-21
 Identities = 73/249 (29%), Positives = 100/249 (40%), Gaps = 47/249 (18%)

Query: 82  CDCNGNSNECLD----------GSGYCVH----CQRNTTGEHCEKCLDGY------IGDS 121
           C CNG++++C+           G+ + VH    C+ NT G HC+ C   Y        D 
Sbjct: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADG 321

Query: 122 IRGAPQFCQPCPC----PLPHL-ANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176
             GAP  C+ C C       H   N  E+   ++G V   C  N  G  C+RC PG+Y +
Sbjct: 322 KTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRD 381

Query: 177 ---PLLIGSTCKKCDCSGNSD---PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG 230
              P      CK C C        P      CD   G C  C     G +C+RC  GY+G
Sbjct: 382 LRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC-PCKPGVAGRRCDRCMVGYWG 440

Query: 231 DARIAKNCAVCNCGGGPCDSVTGECLEE-----------GFEPPTGCDKCVWDLTDALRL 279
                  C  C+C G  CD +TG+C+              F P     +  W+  DA   
Sbjct: 441 FGDY--GCRPCDCAGS-CDPITGDCISSHTDIDWYHEVPDFRPVHNKSEPAWEWEDAQGF 497

Query: 280 AALSIEEGK 288
           +AL +  GK
Sbjct: 498 SAL-LHSGK 505



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 52/151 (34%), Positives = 67/151 (44%), Gaps = 35/151 (23%)

Query: 78  ECVPCDCNGNSNECL-----------DGSGYCVHCQRNTTGEHCEKCLDGYIGDSIR--G 124
           EC  C CNG+++ C               G C  CQ NT G++C++C  G+  D  R   
Sbjct: 328 ECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFS 387

Query: 125 APQFCQPCPC------PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
           AP  C+PC C       LP  AN    C   NG   C C    AG  C+RC  GY+G   
Sbjct: 388 APDACKPCSCHPVGSAVLP--ANSVTFCDPSNG--DCPCKPGVAGRRCDRCMVGYWG--- 440

Query: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQC 209
                C+ CDC+G+         CD +TG C
Sbjct: 441 FGDYGCRPCDCAGS---------CDPITGDC 462


>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
          Length = 1172

 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 67/202 (33%), Positives = 92/202 (45%), Gaps = 26/202 (12%)

Query: 78  ECVPCDCNGNSNEC---------LDGS--GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
           EC  CDCNG+S  C           G+  G C +C+ +T G++CE+C   Y  +   GA 
Sbjct: 312 ECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGAS 371

Query: 127 --QFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
             + C  C C  P  A     C    G  +C+C E+  G  C+ C PG+ G        C
Sbjct: 372 IQETCISCECD-PDGAVPGAPCDPVTG--QCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428

Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244
            +CDC  N   +     CDE +G+C  CL N  G KC++CAP Y+      + C  C C 
Sbjct: 429 HRCDC--NILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACD 484

Query: 245 -----GGPCDSVTGEC-LEEGF 260
                   C+  TG+C   EGF
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGF 506



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 175/784 (22%), Positives = 297/784 (37%), Gaps = 134/784 (17%)

Query: 79   CVPCDCN--GNSNE--CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPC 134
            C  CDCN  G+  +  C + SG C+ C  N  G  C++C   Y      G  Q C+PC C
Sbjct: 428  CHRCDCNILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASG--QGCEPCAC 483

Query: 135  PLPHLANFAESCYRKNGAVRCICNENYAGPNCE-----RCAPGYYGNPLLIGSTCKKCDC 189
              PH  + +  C +  G  +C C E + G  C      +C    YG+   + + C+ CDC
Sbjct: 484  D-PH-NSLSPQCNQFTG--QCPCREGFGGLMCSAAAIRQCPDRTYGD---VATGCRACDC 536

Query: 190  S--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGP 247
               G   P      CD+ +G+C  C    TG +C++C  GY     +   C  C+    P
Sbjct: 537  DFRGTEGPG-----CDKASGRCL-CRPGLTGPRCDQCQRGYCNRYPV---CVACH----P 583

Query: 248  CDSVTGECLEE---GFEPPTGCDKCVWD---LTDALRLAALSIEEGKSGVLSV----SSG 297
            C       L E    F         +W    L D  R  A  I + KS +  +    SS 
Sbjct: 584  CFQTYDADLREQALRFGRLRNATASLWSGPGLED--RGLASRILDAKSKIEQIRAVLSSP 641

Query: 298  AAAHRHVNEINATIYLLKTKLS--------ERENQYALRKIQ-INNAENTMKSLLSDVEE 348
            A   + V ++ + I  L+  L         E E     R ++ ++ + N + ++     E
Sbjct: 642  AVTEQEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKRE 701

Query: 349  LVEKENQASRKGQL--------VQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGE 400
              EK + A   G             ++   ++ +S+L++Q  D R + + +  +    G 
Sbjct: 702  QFEKISSADPSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGG 761

Query: 401  EHELSPKEISEKLVLAQKMLEEIRSRQPFFTQ-----RELVDEEADEAYELLSQAESWQR 455
                     S KLV  +  +  +    P F +     R++         EL  Q ++   
Sbjct: 762  TG-------SPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQ-DNGTA 813

Query: 456  LHNETRTLFP----------VVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAAR 505
              +  R + P           V EQL  +NA+L   ++        +R AE+      + 
Sbjct: 814  CGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQ-------MIRAAEESASQIQSS 866

Query: 506  QRDHEKQQERVREQMEV----VNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGA 561
             +  E Q    R QME       + +    D LT P    + + ++ +    ++   D A
Sbjct: 867  AQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSA 926

Query: 562  -----KSELQVKLSNLSNLSHDLVQ--EAIDHAQDLQQEANELSRKLHSSDMNGLVQKAL 614
                  +E+Q   + L N+   L Q  + I  A+ LQ EA E   + H+  + G V+  +
Sbjct: 927  TVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHA--VEGQVEDVV 984

Query: 615  DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQA 674
               N+ +  V  + EA +T +    +   I D V+ +   +   +    ++  Q  +   
Sbjct: 985  --GNLRQGTV-ALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWT 1041

Query: 675  KAESSSDEAVADTSRRVGGALARKSALKTRLS-----DAVKQLQAAERGDAQQRLGQSRL 729
            + E    +A    +  V      + A +  LS     + +KQ  A    + + RLGQS +
Sbjct: 1042 RMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYA----ELKDRLGQSSM 1097

Query: 730  ITEEANR-------------TTMEVQQATAPMANNLTNWSQ--NLQHFDSSAYNTAVNSA 774
            + E+  R              TME+      M   L   SQ   L+  D +     V   
Sbjct: 1098 LGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQI 1157

Query: 775  RDAV 778
            RD +
Sbjct: 1158 RDHI 1161



 Score = 92.0 bits (227), Expect = 5e-18
 Identities = 50/135 (37%), Positives = 63/135 (46%), Gaps = 20/135 (14%)

Query: 155 CICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNLIFEDCDE 204
           C+C  N AGPNCERCAP Y   P           C++CDC+G+S     DP +       
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338

Query: 205 VTGQCRNCLRNTTGFKCERCAPGYYGDAR----IAKNCAVCNCG------GGPCDSVTGE 254
             G C NC  +T G  CERC   Y+ + R    I + C  C C       G PCD VTG+
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398

Query: 255 CLEEGFEPPTGCDKC 269
           C+ +       CD C
Sbjct: 399 CVCKEHVQGERCDLC 413



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 67/225 (29%), Positives = 90/225 (40%), Gaps = 46/225 (20%)

Query: 82  CDCNGNSNECLDGSG-------------YCVHCQRNTTGEHCEKCLDGYIGDSIRGA--- 125
           C C+G+++ C    G              CV CQ NT G +CE+C   Y     R A   
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308

Query: 126 -PQFCQPCPCPLPHLANFAESCY----------RKNGAVRCICNENYAGPNCERCAPGYY 174
               CQ C C        +E+C+             G V   C ++  G NCERC   Y+
Sbjct: 309 DAHECQRCDC-----NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363

Query: 175 GN---PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG- 230
            N      I  TC  C+C  + D  +    CD VTGQC  C  +  G +C+ C PG+ G 
Sbjct: 364 RNRRPGASIQETCISCEC--DPDGAVPGAPCDPVTGQC-VCKEHVQGERCDLCKPGFTGL 420

Query: 231 DARIAKNCAVCNCG------GGPCDSVTGECLEEGFEPPTGCDKC 269
                + C  C+C         PCD  +G CL         CD+C
Sbjct: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQC 465



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 18/121 (14%)

Query: 62  PAAEKCNAGFFHTLSGE-CVPCDC---NGNSNECLDGSGYCVHCQRNTTGEHCE-----K 112
           P  ++C    +   SG+ C PC C   N  S +C   +G C  C+    G  C      +
Sbjct: 460 PKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCP-CREGFGGLMCSAAAIRQ 518

Query: 113 CLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172
           C D   GD   G    C+ C C           C + +G  RC+C     GP C++C  G
Sbjct: 519 CPDRTYGDVATG----CRACDCDFR--GTEGPGCDKASG--RCLCRPGLTGPRCDQCQRG 570

Query: 173 Y 173
           Y
Sbjct: 571 Y 571


>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
          Length = 1172

 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 67/202 (33%), Positives = 92/202 (45%), Gaps = 26/202 (12%)

Query: 78  ECVPCDCNGNSNEC---------LDGS--GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
           EC  CDCNG+S  C           G+  G C +C+ +T G++CE+C   Y  +   GA 
Sbjct: 312 ECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGAS 371

Query: 127 --QFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
             + C  C C  P  A     C    G  +C+C E+  G  C+ C PG+ G        C
Sbjct: 372 IQETCISCECD-PDGAVPGAPCDPVTG--QCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428

Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244
            +CDC  N   +     CDE +G+C  CL N  G KC++CAP Y+      + C  C C 
Sbjct: 429 HRCDC--NILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACD 484

Query: 245 -----GGPCDSVTGEC-LEEGF 260
                   C+  TG+C   EGF
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGF 506



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 175/784 (22%), Positives = 297/784 (37%), Gaps = 134/784 (17%)

Query: 79   CVPCDCN--GNSNE--CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPC 134
            C  CDCN  G+  +  C + SG C+ C  N  G  C++C   Y      G  Q C+PC C
Sbjct: 428  CHRCDCNILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASG--QGCEPCAC 483

Query: 135  PLPHLANFAESCYRKNGAVRCICNENYAGPNCE-----RCAPGYYGNPLLIGSTCKKCDC 189
              PH  + +  C +  G  +C C E + G  C      +C    YG+   + + C+ CDC
Sbjct: 484  D-PH-NSLSPQCNQFTG--QCPCREGFGGLMCSAAAIRQCPDRTYGD---VATGCRACDC 536

Query: 190  S--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGP 247
               G   P      CD+ +G+C  C    TG +C++C  GY     +   C  C+    P
Sbjct: 537  DFRGTEGPG-----CDKASGRCL-CRPGLTGPRCDQCQRGYCNRYPV---CVACH----P 583

Query: 248  CDSVTGECLEE---GFEPPTGCDKCVWD---LTDALRLAALSIEEGKSGVLSV----SSG 297
            C       L E    F         +W    L D  R  A  I + KS +  +    SS 
Sbjct: 584  CFQTYDADLREQALRFGRLRNATASLWSGPGLED--RGLASRILDAKSKIEQIRAVLSSP 641

Query: 298  AAAHRHVNEINATIYLLKTKLS--------ERENQYALRKIQ-INNAENTMKSLLSDVEE 348
            A   + V ++ + I  L+  L         E E     R ++ ++ + N + ++     E
Sbjct: 642  AVTEQEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKRE 701

Query: 349  LVEKENQASRKGQL--------VQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGE 400
              EK + A   G             ++   ++ +S+L++Q  D R + + +  +    G 
Sbjct: 702  QFEKISSADPSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGG 761

Query: 401  EHELSPKEISEKLVLAQKMLEEIRSRQPFFTQ-----RELVDEEADEAYELLSQAESWQR 455
                     S KLV  +  +  +    P F +     R++         EL  Q ++   
Sbjct: 762  TG-------SPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQ-DNGTA 813

Query: 456  LHNETRTLFP----------VVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAAR 505
              +  R + P           V EQL  +NA+L   ++        +R AE+      + 
Sbjct: 814  CGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQ-------MIRAAEESASQIQSS 866

Query: 506  QRDHEKQQERVREQMEV----VNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGA 561
             +  E Q    R QME       + +    D LT P    + + ++ +    ++   D A
Sbjct: 867  AQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSA 926

Query: 562  -----KSELQVKLSNLSNLSHDLVQ--EAIDHAQDLQQEANELSRKLHSSDMNGLVQKAL 614
                  +E+Q   + L N+   L Q  + I  A+ LQ EA E   + H+  + G V+  +
Sbjct: 927  TVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHA--VEGQVEDVV 984

Query: 615  DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQA 674
               N+ +  V  + EA +T +    +   I D V+ +   +   +    ++  Q  +   
Sbjct: 985  --GNLRQGTV-ALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWT 1041

Query: 675  KAESSSDEAVADTSRRVGGALARKSALKTRLS-----DAVKQLQAAERGDAQQRLGQSRL 729
            + E    +A    +  V      + A +  LS     + +KQ  A    + + RLGQS +
Sbjct: 1042 RMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYA----ELKDRLGQSSM 1097

Query: 730  ITEEANR-------------TTMEVQQATAPMANNLTNWSQ--NLQHFDSSAYNTAVNSA 774
            + E+  R              TME+      M   L   SQ   L+  D +     V   
Sbjct: 1098 LGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQI 1157

Query: 775  RDAV 778
            RD +
Sbjct: 1158 RDHI 1161



 Score = 92.0 bits (227), Expect = 5e-18
 Identities = 50/135 (37%), Positives = 63/135 (46%), Gaps = 20/135 (14%)

Query: 155 CICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNLIFEDCDE 204
           C+C  N AGPNCERCAP Y   P           C++CDC+G+S     DP +       
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338

Query: 205 VTGQCRNCLRNTTGFKCERCAPGYYGDAR----IAKNCAVCNCG------GGPCDSVTGE 254
             G C NC  +T G  CERC   Y+ + R    I + C  C C       G PCD VTG+
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398

Query: 255 CLEEGFEPPTGCDKC 269
           C+ +       CD C
Sbjct: 399 CVCKEHVQGERCDLC 413



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 67/225 (29%), Positives = 90/225 (40%), Gaps = 46/225 (20%)

Query: 82  CDCNGNSNECLDGSG-------------YCVHCQRNTTGEHCEKCLDGYIGDSIRGA--- 125
           C C+G+++ C    G              CV CQ NT G +CE+C   Y     R A   
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308

Query: 126 -PQFCQPCPCPLPHLANFAESCY----------RKNGAVRCICNENYAGPNCERCAPGYY 174
               CQ C C        +E+C+             G V   C ++  G NCERC   Y+
Sbjct: 309 DAHECQRCDC-----NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363

Query: 175 GN---PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG- 230
            N      I  TC  C+C  + D  +    CD VTGQC  C  +  G +C+ C PG+ G 
Sbjct: 364 RNRRPGASIQETCISCEC--DPDGAVPGAPCDPVTGQC-VCKEHVQGERCDLCKPGFTGL 420

Query: 231 DARIAKNCAVCNCG------GGPCDSVTGECLEEGFEPPTGCDKC 269
                + C  C+C         PCD  +G CL         CD+C
Sbjct: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQC 465



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 18/121 (14%)

Query: 62  PAAEKCNAGFFHTLSGE-CVPCDC---NGNSNECLDGSGYCVHCQRNTTGEHCE-----K 112
           P  ++C    +   SG+ C PC C   N  S +C   +G C  C+    G  C      +
Sbjct: 460 PKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCP-CREGFGGLMCSAAAIRQ 518

Query: 113 CLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172
           C D   GD   G    C+ C C           C + +G  RC+C     GP C++C  G
Sbjct: 519 CPDRTYGDVATG----CRACDCDFR--GTEGPGCDKASG--RCLCRPGLTGPRCDQCQRG 570

Query: 173 Y 173
           Y
Sbjct: 571 Y 571


>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
          Length = 1172

 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 67/202 (33%), Positives = 92/202 (45%), Gaps = 26/202 (12%)

Query: 78  ECVPCDCNGNSNEC---------LDGS--GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
           EC  CDCNG+S  C           G+  G C +C+ +T G++CE+C   Y  +   GA 
Sbjct: 312 ECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGAS 371

Query: 127 --QFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
             + C  C C  P  A     C    G  +C+C E+  G  C+ C PG+ G        C
Sbjct: 372 IQETCISCECD-PDGAVPGAPCDPVTG--QCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428

Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244
            +CDC  N   +     CDE +G+C  CL N  G KC++CAP Y+      + C  C C 
Sbjct: 429 HRCDC--NILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACD 484

Query: 245 -----GGPCDSVTGEC-LEEGF 260
                   C+  TG+C   EGF
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGF 506



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 175/784 (22%), Positives = 297/784 (37%), Gaps = 134/784 (17%)

Query: 79   CVPCDCN--GNSNE--CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPC 134
            C  CDCN  G+  +  C + SG C+ C  N  G  C++C   Y      G  Q C+PC C
Sbjct: 428  CHRCDCNILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASG--QGCEPCAC 483

Query: 135  PLPHLANFAESCYRKNGAVRCICNENYAGPNCE-----RCAPGYYGNPLLIGSTCKKCDC 189
              PH  + +  C +  G  +C C E + G  C      +C    YG+   + + C+ CDC
Sbjct: 484  D-PH-NSLSPQCNQFTG--QCPCREGFGGLMCSAAAIRQCPDRTYGD---VATGCRACDC 536

Query: 190  S--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGP 247
               G   P      CD+ +G+C  C    TG +C++C  GY     +   C  C+    P
Sbjct: 537  DFRGTEGPG-----CDKASGRCL-CRPGLTGPRCDQCQRGYCNRYPV---CVACH----P 583

Query: 248  CDSVTGECLEE---GFEPPTGCDKCVWD---LTDALRLAALSIEEGKSGVLSV----SSG 297
            C       L E    F         +W    L D  R  A  I + KS +  +    SS 
Sbjct: 584  CFQTYDADLREQALRFGRLRNATASLWSGPGLED--RGLASRILDAKSKIEQIRAVLSSP 641

Query: 298  AAAHRHVNEINATIYLLKTKLS--------ERENQYALRKIQ-INNAENTMKSLLSDVEE 348
            A   + V ++ + I  L+  L         E E     R ++ ++ + N + ++     E
Sbjct: 642  AVTEQEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKRE 701

Query: 349  LVEKENQASRKGQL--------VQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGE 400
              EK + A   G             ++   ++ +S+L++Q  D R + + +  +    G 
Sbjct: 702  QFEKISSADPSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGG 761

Query: 401  EHELSPKEISEKLVLAQKMLEEIRSRQPFFTQ-----RELVDEEADEAYELLSQAESWQR 455
                     S KLV  +  +  +    P F +     R++         EL  Q ++   
Sbjct: 762  TG-------SPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQ-DNGTA 813

Query: 456  LHNETRTLFP----------VVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAAR 505
              +  R + P           V EQL  +NA+L   ++        +R AE+      + 
Sbjct: 814  CGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQ-------MIRAAEESASQIQSS 866

Query: 506  QRDHEKQQERVREQMEV----VNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGA 561
             +  E Q    R QME       + +    D LT P    + + ++ +    ++   D A
Sbjct: 867  AQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSA 926

Query: 562  -----KSELQVKLSNLSNLSHDLVQ--EAIDHAQDLQQEANELSRKLHSSDMNGLVQKAL 614
                  +E+Q   + L N+   L Q  + I  A+ LQ EA E   + H+  + G V+  +
Sbjct: 927  TVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHA--VEGQVEDVV 984

Query: 615  DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQA 674
               N+ +  V  + EA +T +    +   I D V+ +   +   +    ++  Q  +   
Sbjct: 985  --GNLRQGTV-ALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWT 1041

Query: 675  KAESSSDEAVADTSRRVGGALARKSALKTRLS-----DAVKQLQAAERGDAQQRLGQSRL 729
            + E    +A    +  V      + A +  LS     + +KQ  A    + + RLGQS +
Sbjct: 1042 RMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYA----ELKDRLGQSSM 1097

Query: 730  ITEEANR-------------TTMEVQQATAPMANNLTNWSQ--NLQHFDSSAYNTAVNSA 774
            + E+  R              TME+      M   L   SQ   L+  D +     V   
Sbjct: 1098 LGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQI 1157

Query: 775  RDAV 778
            RD +
Sbjct: 1158 RDHI 1161



 Score = 92.0 bits (227), Expect = 5e-18
 Identities = 50/135 (37%), Positives = 63/135 (46%), Gaps = 20/135 (14%)

Query: 155 CICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNLIFEDCDE 204
           C+C  N AGPNCERCAP Y   P           C++CDC+G+S     DP +       
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338

Query: 205 VTGQCRNCLRNTTGFKCERCAPGYYGDAR----IAKNCAVCNCG------GGPCDSVTGE 254
             G C NC  +T G  CERC   Y+ + R    I + C  C C       G PCD VTG+
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398

Query: 255 CLEEGFEPPTGCDKC 269
           C+ +       CD C
Sbjct: 399 CVCKEHVQGERCDLC 413



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 67/225 (29%), Positives = 90/225 (40%), Gaps = 46/225 (20%)

Query: 82  CDCNGNSNECLDGSG-------------YCVHCQRNTTGEHCEKCLDGYIGDSIRGA--- 125
           C C+G+++ C    G              CV CQ NT G +CE+C   Y     R A   
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308

Query: 126 -PQFCQPCPCPLPHLANFAESCY----------RKNGAVRCICNENYAGPNCERCAPGYY 174
               CQ C C        +E+C+             G V   C ++  G NCERC   Y+
Sbjct: 309 DAHECQRCDC-----NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363

Query: 175 GN---PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG- 230
            N      I  TC  C+C  + D  +    CD VTGQC  C  +  G +C+ C PG+ G 
Sbjct: 364 RNRRPGASIQETCISCEC--DPDGAVPGAPCDPVTGQC-VCKEHVQGERCDLCKPGFTGL 420

Query: 231 DARIAKNCAVCNCG------GGPCDSVTGECLEEGFEPPTGCDKC 269
                + C  C+C         PCD  +G CL         CD+C
Sbjct: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQC 465



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 18/121 (14%)

Query: 62  PAAEKCNAGFFHTLSGE-CVPCDC---NGNSNECLDGSGYCVHCQRNTTGEHCE-----K 112
           P  ++C    +   SG+ C PC C   N  S +C   +G C  C+    G  C      +
Sbjct: 460 PKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCP-CREGFGGLMCSAAAIRQ 518

Query: 113 CLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172
           C D   GD   G    C+ C C           C + +G  RC+C     GP C++C  G
Sbjct: 519 CPDRTYGDVATG----CRACDCDFR--GTEGPGCDKASG--RCLCRPGLTGPRCDQCQRG 570

Query: 173 Y 173
           Y
Sbjct: 571 Y 571


>gi|219842259 usherin isoform A [Homo sapiens]
          Length = 1546

 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 61/219 (27%), Positives = 88/219 (40%), Gaps = 38/219 (17%)

Query: 79  CVPCDCNGNSNEC--------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGD--SI 122
           C PC CN +S  C                G G C  C+ NTTG +CE C D +     + 
Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631

Query: 123 RGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGS 182
             A   C+PC C      N +  C +  G  +C C  + +G  C +C  G+Y    L   
Sbjct: 632 PSAIDVCKPCDCDTVGTRNGSILCDQIGG--QCNCKRHVSGRQCNQCQNGFYNLQELDPD 689

Query: 183 TCKKCDC--SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGY-----YGDARIA 235
            C  C+C  SG  D ++    C + +GQC+ C  N  G +C+ C  G+     + D    
Sbjct: 690 GCSPCNCNTSGTVDGDI---TCHQNSGQCK-CKANVIGLRCDHCNFGFKFLRSFNDV--- 742

Query: 236 KNCAVCNCG-----GGPCDSVTGECLEEGFEPPTGCDKC 269
             C  C C         C+  +G+C  +       CD C
Sbjct: 743 -GCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTC 780



 Score = 87.8 bits (216), Expect = 9e-17
 Identities = 66/230 (28%), Positives = 98/230 (42%), Gaps = 47/230 (20%)

Query: 74  TLSGECVPCDCNGNSNEC-LDGSGYCVHCQRN--TTGEHCEKCLDGYIGDSIRGAPQF-- 128
           T+SG C    C+G+++ C      Y   C +   T G HC++CL  Y     R   Q   
Sbjct: 513 TISGRC---QCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569

Query: 129 --CQPCPCPLPHLANFAESC-------------YRKNGAVRCICNENYAGPNCERCAPGY 173
             C+PC C      + ++SC             +R  G V   C  N  G NCE C   +
Sbjct: 570 FNCKPCQC-----NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYF 624

Query: 174 Y----GNPLLIGSTCKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG 227
           +     +P  I   CK CDC   G  + +++   CD++ GQC NC R+ +G +C +C  G
Sbjct: 625 FRQVGADPSAI-DVCKPCDCDTVGTRNGSIL---CDQIGGQC-NCKRHVSGRQCNQCQNG 679

Query: 228 YYGDARI-AKNCAVCNC-------GGGPCDSVTGECLEEGFEPPTGCDKC 269
           +Y    +    C+ CNC       G   C   +G+C  +       CD C
Sbjct: 680 FYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHC 729



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 65/224 (29%), Positives = 95/224 (42%), Gaps = 35/224 (15%)

Query: 65  EKCNAGFFHTLSGE---CVPCDCN--GNSNE-CLDGSGYCVHCQRNTTGEHCEKCLDGYI 118
           + CN GF    S     C PC CN  G+ N+ C   SG C  C++   G  C+ C + + 
Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAKGLQCDTCRENFY 785

Query: 119 GDSIRGAPQFCQPCPC----PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
           G  +      C+ C C     LP        C  K G  +CIC  N  G  C +C  G +
Sbjct: 786 GLDVTN----CKACDCDTAGSLP-----GTVCNAKTG--QCICKPNVEGRQCNKCLEGNF 834

Query: 175 GNPLLIGSTCKKCDC--SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-D 231
                    C  C+C  +G  + +L+   C++ TGQC  C    TG +C +C P  Y   
Sbjct: 835 YLRQNNSFLCLPCNCDKTGTINGSLL---CNKSTGQC-PCKLGVTGLRCNQCEPHRYNLT 890

Query: 232 ARIAKNCAVCNCG------GGPCDSVTGECLEEGFEPPTGCDKC 269
               ++C +C C       G  CD ++G+CL         C++C
Sbjct: 891 IDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQC 934



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 66/222 (29%), Positives = 91/222 (40%), Gaps = 30/222 (13%)

Query: 66   KCNAGFFHTLSGE---CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117
            KC  G F+        C+PC+C+       S  C   +G C  C+   TG  C +C    
Sbjct: 828  KCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCP-CKLGVTGLRCNQCEPHR 886

Query: 118  IGDSIRGAPQFCQPCPCP----LPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGY 173
               +I    Q CQ C C     LP        C   +G  +C+C  N  G  C +C PG+
Sbjct: 887  YNLTIDNF-QHCQMCECDSLGTLP-----GTICDPISG--QCLCVPNRQGRRCNQCQPGF 938

Query: 174  YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR 233
            Y +P    + C  C C      N I   C+ +TGQC     +  G +C++C   Y+G   
Sbjct: 939  YISPGN-ATGCLPCSCHTTGAVNHI---CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDP 994

Query: 234  IAKNCAVCNCG-----GGPCDSVTGECLEEGFEPPTGCDKCV 270
                C  CNC         C  VTG+C  + F   + CD CV
Sbjct: 995  QTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 48/153 (31%), Positives = 65/153 (42%), Gaps = 17/153 (11%)

Query: 79   CVPCDCNG----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPC 134
            C  C+C+         C   SG C+ C  N  G  C +C  G+      G    C PC C
Sbjct: 897  CQMCECDSLGTLPGTICDPISGQCL-CVPNRQGRRCNQCQPGFYISP--GNATGCLPCSC 953

Query: 135  PLPHLANFAESCYRKNGAVRCICNE-NYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNS 193
                  N    C    G  +C+C + + AG  C++C   Y+G     G  C+ C+C  + 
Sbjct: 954  HTTGAVNHI--CNSLTG--QCVCQDASIAGQRCDQCKDHYFGFDPQTGR-CQPCNCHLSG 1008

Query: 194  DPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226
              N   E C  VTGQC  C +  TG KC+ C P
Sbjct: 1009 ALN---ETCHLVTGQCF-CKQFVTGSKCDACVP 1037



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 35/112 (31%), Positives = 52/112 (46%), Gaps = 13/112 (11%)

Query: 66   KCNAGFFHTLSGE--CVPCDCNGN---SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG- 119
            +C  GF+ +      C+PC C+     ++ C   +G CV    +  G+ C++C D Y G 
Sbjct: 933  QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992

Query: 120  DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAP 171
            D   G    CQPC C L    N  E+C+   G  +C C +   G  C+ C P
Sbjct: 993  DPQTGR---CQPCNCHLSGALN--ETCHLVTG--QCFCKQFVTGSKCDACVP 1037


>gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]
          Length = 1547

 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 163/849 (19%), Positives = 315/849 (37%), Gaps = 136/849 (16%)

Query: 1045 FDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFY 1104
            F GS Y    D+++           +  +T   NGL+L     + +  L ++NG + +  
Sbjct: 319  FKGSEYFCY-DLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVI 377

Query: 1105 DFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMIL---VVDRRHVK---SMDNEK 1158
            + G       +E      + ND  +H++ +  +  +   +   +V++ H     S+D   
Sbjct: 378  NLGSGAFEALVEPV--NGKFNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGIL 435

Query: 1159 MKIPFTD-----------IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNL 1207
                +T             Y+GG+P     S A     P+  NF GC+K   ++  D  L
Sbjct: 436  TTTGYTQEDYTMLGSDDFFYVGGSP-----STADLPGSPVSNNFMGCLKEVVYKNNDVRL 490

Query: 1208 -LEQTETLG---------VGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFR 1257
             L +    G         V + C   + +    +   +SFI S+ K +        F+FR
Sbjct: 491  ELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFI-SLPKWNAKKTGSISFDFR 549

Query: 1258 TLQPNGLLFYYASGS--------------DVFSISLDNGTV--IMDVKG--IKVQSVDKQ 1299
            T +PNGL+ +                   D F+I + +G +  ++D+    IK++++ K+
Sbjct: 550  TTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKK 609

Query: 1300 YNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSP------- 1352
             NDG  + V          + V+  R     P + +I      + + Y GG P       
Sbjct: 610  VNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDL---DDELYLGGLPENKAGLV 666

Query: 1353 ------ISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLH 1406
                   +     + GCI + +     +D+      + T  V  S               
Sbjct: 667  FPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSC-------------- 712

Query: 1407 KKGKNLSKPKASQN-KKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQY 1465
               K  +KP  S   K  G  +D   W+                 +L  S         Y
Sbjct: 713  --SKETAKPCLSNPCKNNGMCRDG--WNRYVCDCSGTG-------YLGRSCEREATVLSY 761

Query: 1466 GGTANSRQEFE---HLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRL 1522
             G+   + +     H + +       S+R R++ ++G++   + ++  D + L L  GR+
Sbjct: 762  DGSMFMKIQLPVVMHTEAE-----DVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRV 816

Query: 1523 VYMFNVGHKKLKIRSQE---------KYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLP 1573
                N+   ++   S +           ND  WH V  +R   S +L +D  + +   + 
Sbjct: 817  KLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMA 876

Query: 1574 PTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPC 1633
                  +    I  G +   + + +V  N    F G L +L  NG +     +   +  C
Sbjct: 877  GDHTRLEFHN-IETGIITERRYLSSVPSN----FIGHLQSLTFNGMAYIDLCKNGDIDYC 931

Query: 1634 -------FEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNG 1686
                   F   +     F T+  YV L  +        + F+ +  S  G +++      
Sbjct: 932  ELNARFGFRNIIADPVTFKTKSSYVAL-ATLQAYTSMHLFFQFKTTSLDGLILYNSGDGN 990

Query: 1687 EYLNVHMKNGQV--IVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRD-SNVVQLDVDSE 1743
            +++ V +  G +  +  + NG      S    + L D +WH + + RD SN+  + +D++
Sbjct: 991  DFIVVELVKGYLHYVFDLGNGANLIKGS--SNKPLNDNQWHNVMISRDTSNLHTVKIDTK 1048

Query: 1744 VNHVVGPLNPKPIDHREPVFVGGVPESLL--TPRLAPSKP-FTGCIRHFVIDGH-PVSFS 1799
            +   +     + +D +  +++GGV +      P+L  +K  F GC+    ++G  P   S
Sbjct: 1049 ITTQI-TAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLIS 1107

Query: 1800 KAALVSGAV 1808
             A   +G +
Sbjct: 1108 DALFCNGQI 1116



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 87/371 (23%), Positives = 143/371 (38%), Gaps = 48/371 (12%)

Query: 886  EYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIER-------VGKHGKV 938
            +Y+ LA+KN  +  V NLG+   E  ++          +  VK+ R       +G H  V
Sbjct: 362  DYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIG-HAMV 420

Query: 939  FLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGC 998
                 S++ + +      G    D ++L     D  FYVGG PS   LP S     F+GC
Sbjct: 421  NKLHCSVTISVDGILTTTGYTQEDYTMLG---SDDFFYVGGSPSTADLPGSPVSNNFMGC 477

Query: 999  LELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITR 1058
            L+     N+ + L   +     DP   +      +AF     A+   D   +        
Sbjct: 478  LKEVVYKNNDVRLELSRLAKQGDPKMKI---HGVVAFKCENVAT--LDPITFETPESFIS 532

Query: 1059 RGKFG--QVTRFDIEVRTPADNGLILL---------------MVNGSMFFRLEMRNGYLH 1101
              K+   +      + RT   NGLIL                M+    FF +EM +G+L+
Sbjct: 533  LPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVD-FFAIEMLDGHLY 591

Query: 1102 VFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKI 1161
            +  D G   G + ++  LKK  +ND +++ +          I V   R   +   E   +
Sbjct: 592  LLLDMG--SGTIKIKALLKK--VNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEIL 647

Query: 1162 PFTD-IYIGGAPPE----ILQSRALRAHLPLDINFRGCMKG--FQFQKKDF-NLLEQTET 1213
               D +Y+GG P      +  +    A   L+  + GC++      Q KD   + E   T
Sbjct: 648  DLDDELYLGGLPENKAGLVFPTEVWTA--LLNYGYVGCIRDLFIDGQSKDIRQMAEVQST 705

Query: 1214 LGVGYGCPEDS 1224
             GV   C +++
Sbjct: 706  AGVKPSCSKET 716



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 35/144 (24%), Positives = 68/144 (47%), Gaps = 7/144 (4%)

Query: 1485 KSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAH-GRLVYMFNV-GHKKLKIRSQEKYN 1542
            +S+ S +L+TRS+ G++ Y  D+   DF+ L L   GRL   F++   +   + +    N
Sbjct: 51   ESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVN 110

Query: 1543 DGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAP--GKAVKNVQ 1600
            DG WH V   R+  +  L ID +      +        +   +++GG+ P    A   + 
Sbjct: 111  DGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLT 170

Query: 1601 INSIYS---FSGCLSNLQLNGASI 1621
            + S+     F G + ++++N + +
Sbjct: 171  LASVREREPFKGWIRDVRVNSSQV 194



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 145/764 (18%), Positives = 275/764 (35%), Gaps = 143/764 (18%)

Query: 884  KKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVP 943
            K ++  + + + +L  + ++G+  ++I    K V+    Y   V  +R G+ G + +   
Sbjct: 577  KVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYH--VDFQRDGRSGTISVNTL 634

Query: 944  SLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSN-------FKLPTSLNLPGFV 996
                TA           G+  +LDLD E    Y+GG+P N        ++ T+L   G+V
Sbjct: 635  RTPYTAP----------GESEILDLDDE---LYLGGLPENKAGLVFPTEVWTALLNYGYV 681

Query: 997  GCLE---LATLNNDVISLYNFKHIYNMDPSTSVPCARDKLA-------FTQSRAASYFFD 1046
            GC+    +   + D+  +   +    + PS S   A+  L+         +     Y  D
Sbjct: 682  GCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCD 741

Query: 1047 --GSGY---AVVRDITRRGKFGQV------------TRFDIEVRTPADNGLILLMVNGSM 1089
              G+GY   +  R+ T     G +               D+ +R  +     +LM   S 
Sbjct: 742  CSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSR 801

Query: 1090 ----FFRLEMRNGYLHVFYDF-------GFSGGPVHLEDTLKKAQINDAKYHEISIIYHN 1138
                  RLE+  G + +  +          S GP   E       +ND ++H + ++   
Sbjct: 802  DSADTLRLELDAGRVKLTVNLDCIRINCNSSKGP---ETLFAGYNLNDNEWHTVRVV-RR 857

Query: 1139 DKKMILVVDRRHVKS--MDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMK 1196
             K + L VD +   +  M  +  ++ F +I  G     I+  R   + +P   NF G ++
Sbjct: 858  GKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETG-----IITERRYLSSVPS--NFIGHLQ 910

Query: 1197 GFQF---------QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFF 1247
               F         +  D +  E     G        ++I+    F  +S   ++  +  +
Sbjct: 911  SLTFNGMAYIDLCKNGDIDYCELNARFGFR------NIIADPVTFKTKSSYVALATLQAY 964

Query: 1248 DGFEGGFNFRTLQPNGLLFYYAS-GSDVFSISLDNGTV--IMDV---KGIKVQSVDKQYN 1301
                  F F+T   +GL+ Y +  G+D   + L  G +  + D+     +   S +K  N
Sbjct: 965  TSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLN 1024

Query: 1302 DGLSHFVISSVSPTRYELIVDKSRV------GSKNPTKGKIEQTQASEKKFYFGGSPISA 1355
            D   H V+ S   +    +   +++      G++N             K+ Y     +  
Sbjct: 1025 DNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVH 1084

Query: 1356 QYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKP 1415
                F GC+++     VD +  + D                + S  LF   +  +    P
Sbjct: 1085 AKEGFQGCLAS-----VDLNGRLPD----------------LISDALFCNGQIERGCEGP 1123

Query: 1416 KASQNKKGGKSKDA--PSWDPVALKL-------PERNTPRNSHCHLSNSPRAIEHAYQYG 1466
              +  +    ++      WD  +          P  N P  ++       +     Y++ 
Sbjct: 1124 STTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQI---TYKWP 1180

Query: 1467 GTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMF 1526
                     + L   F    + ++ +R  SS G+          D++ L +  G++   F
Sbjct: 1181 PNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGL---------GDYLELHIHQGKIGVKF 1231

Query: 1527 NVGHKKLKIR-SQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLE 1569
            NVG   + I  S    NDG +H V F R   +  L +D   V+E
Sbjct: 1232 NVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIE 1275



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 71/390 (18%), Positives = 140/390 (35%), Gaps = 74/390 (18%)

Query: 1484 AKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQE---K 1540
            +  + ++  +T   +G++ +    +  D++ L L +G +  + N+G    +   +    K
Sbjct: 337  SSDEITLSFKTLQRNGLMLHTG--KSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGK 394

Query: 1541 YNDGLWHDVIFIRE---------------RSSGRLVIDGLRVLEESLPPTEATWKIKGP- 1584
            +ND  WHDV   R                  S  + +DG+     +   T+  + + G  
Sbjct: 395  FNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILT---TTGYTQEDYTMLGSD 451

Query: 1585 --IYLGGVA-----PGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFS-------- 1629
               Y+GG       PG  V N       +F GCL  +      +       +        
Sbjct: 452  DFFYVGGSPSTADLPGSPVSN-------NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMK 504

Query: 1630 -----VTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHS- 1683
                    C          F T   ++ L + +N      I+F+ R    +G ++  H  
Sbjct: 505  IHGVVAFKCENVATLDPITFETPESFISLPK-WNAKKTGSISFDFRTTEPNGLILFSHGK 563

Query: 1684 ------------VNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIR 1731
                        +  ++  + M +G + + ++ G          K+ + DG W+ +   R
Sbjct: 564  PRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKK-VNDGEWYHVDFQR 622

Query: 1732 DSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPES---LLTP----RLAPSKPFTG 1784
            D     + V++       P   + +D  + +++GG+PE+   L+ P        +  + G
Sbjct: 623  DGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVG 682

Query: 1785 CIRHFVIDGHPVSFSKAALVSGAVSIN-SC 1813
            CIR   IDG      + A V     +  SC
Sbjct: 683  CIRDLFIDGQSKDIRQMAEVQSTAGVKPSC 712



 Score = 35.8 bits (81), Expect = 0.39
 Identities = 37/142 (26%), Positives = 61/142 (42%), Gaps = 21/142 (14%)

Query: 1060 GKFGQVTRF-----------DIEVRTPADNGLILLMVNGSMFFRLEM---RNGYLHVFYD 1105
            G  GQ TRF             +++T +  GL+L   +      LE+   R G L + + 
Sbjct: 35   GAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFS 94

Query: 1106 FGFSGGPVHLEDTLKKAQINDAKYHEISII--YHNDKKMILVVDRRHVKSMDNEKMKIPF 1163
              F   P  L   L    +ND  +H + I   + N    I  V+ + V+     +    F
Sbjct: 95   I-FCAEPATL---LADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVF 150

Query: 1164 TDIYIGGAPPEILQSRALRAHL 1185
            + +++GG PPE L++ AL+  L
Sbjct: 151  SGLFVGGLPPE-LRAAALKLTL 171


>gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]
          Length = 1477

 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 162/843 (19%), Positives = 311/843 (36%), Gaps = 131/843 (15%)

Query: 1045 FDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFY 1104
            F GS Y    D+++           +  +T   NGL+L     + +  L ++NG + +  
Sbjct: 286  FKGSEYFCY-DLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVI 344

Query: 1105 DFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKIPFT 1164
            + G       +E      + ND  +H++ +   N ++   +       S+D       +T
Sbjct: 345  NLGSGAFEALVEPV--NGKFNDNAWHDVKVT-RNLRQHSGIGHAMVTISVDGILTTTGYT 401

Query: 1165 D-----------IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNL-LEQTE 1212
                         Y+GG+P     S A     P+  NF GC+K   ++  D  L L +  
Sbjct: 402  QEDYTMLGSDDFFYVGGSP-----STADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLA 456

Query: 1213 TLG---------VGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQPNG 1263
              G         V + C   + +    +   +SFI S+ K +        F+FRT +PNG
Sbjct: 457  KQGDPKMKIHGVVAFKCENVATLDPITFETPESFI-SLPKWNAKKTGSISFDFRTTEPNG 515

Query: 1264 LLFYYASGS--------------DVFSISLDNGTV--IMDVKG--IKVQSVDKQYNDGLS 1305
            L+ +                   D F+I + +G +  ++D+    IK++++ K+ NDG  
Sbjct: 516  LILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEW 575

Query: 1306 HFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSP------------- 1352
            + V          + V+  R     P + +I      + + Y GG P             
Sbjct: 576  YHVDFQRDGRSGTISVNTLRTPYTAPGESEILDL---DDELYLGGLPENKAGLVFPTEVW 632

Query: 1353 ISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNL 1412
             +     + GCI + +     +D+      + T  V  S                  K  
Sbjct: 633  TALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSC----------------SKET 676

Query: 1413 SKPKASQN-KKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANS 1471
            +KP  S   K  G  +D   W+                 +L  S         Y G+   
Sbjct: 677  AKPCLSNPCKNNGMCRDG--WNRYVCDCSGTG-------YLGRSCEREATVLSYDGSMFM 727

Query: 1472 RQEFE---HLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNV 1528
            + +     H + +       S+R R++ ++G++   + ++  D + L L  GR+    N+
Sbjct: 728  KIQLPVVMHTEAE-----DVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNL 782

Query: 1529 GHKKLKIRSQE---------KYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATW 1579
               ++   S +           ND  WH V  +R   S +L +D  + +   +       
Sbjct: 783  DCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRL 842

Query: 1580 KIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPC------ 1633
            +    I  G +   + + +V  N    F G L +L  NG +     +   +  C      
Sbjct: 843  EFHN-IETGIITERRYLSSVPSN----FIGHLQSLTFNGMAYIDLCKNGDIDYCELNARF 897

Query: 1634 -FEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVH 1692
             F   +     F T+  YV L  +        + F+ +  S  G +++      +++ V 
Sbjct: 898  GFRNIIADPVTFKTKSSYVAL-ATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVE 956

Query: 1693 MKNGQV--IVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRD-SNVVQLDVDSEVNHVVG 1749
            +  G +  +  + NG      S    + L D +WH + + RD SN+  + +D+++   + 
Sbjct: 957  LVKGYLHYVFDLGNGANLIKGS--SNKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQI- 1013

Query: 1750 PLNPKPIDHREPVFVGGVPESLL--TPRLAPSKP-FTGCIRHFVIDGH-PVSFSKAALVS 1805
                + +D +  +++GGV +      P+L  +K  F GC+    ++G  P   S A   +
Sbjct: 1014 TAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCN 1073

Query: 1806 GAV 1808
            G +
Sbjct: 1074 GQI 1076



 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 88/371 (23%), Positives = 144/371 (38%), Gaps = 55/371 (14%)

Query: 886  EYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIER-------VGKHGKV 938
            +Y+ LA+KN  +  V NLG+   E  ++          +  VK+ R       +G H  V
Sbjct: 329  DYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIG-HAMV 387

Query: 939  FLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGC 998
             ++V  + +T        G    D ++L     D  FYVGG PS   LP S     F+GC
Sbjct: 388  TISVDGILTTT-------GYTQEDYTMLG---SDDFFYVGGSPSTADLPGSPVSNNFMGC 437

Query: 999  LELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITR 1058
            L+     N+ + L   +     DP   +      +AF     A+   D   +        
Sbjct: 438  LKEVVYKNNDVRLELSRLAKQGDPKMKI---HGVVAFKCENVAT--LDPITFETPESFIS 492

Query: 1059 RGKFG--QVTRFDIEVRTPADNGLILL---------------MVNGSMFFRLEMRNGYLH 1101
              K+   +      + RT   NGLIL                M+    FF +EM +G+L+
Sbjct: 493  LPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVD-FFAIEMLDGHLY 551

Query: 1102 VFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKI 1161
            +  D G   G + ++  LKK  +ND +++ +          I V   R   +   E   +
Sbjct: 552  LLLDMG--SGTIKIKALLKK--VNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEIL 607

Query: 1162 PFTD-IYIGGAPPE----ILQSRALRAHLPLDINFRGCMKG--FQFQKKDF-NLLEQTET 1213
               D +Y+GG P      +  +    A   L+  + GC++      Q KD   + E   T
Sbjct: 608  DLDDELYLGGLPENKAGLVFPTEVWTA--LLNYGYVGCIRDLFIDGQSKDIRQMAEVQST 665

Query: 1214 LGVGYGCPEDS 1224
             GV   C +++
Sbjct: 666  AGVKPSCSKET 676



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 157/817 (19%), Positives = 293/817 (35%), Gaps = 155/817 (18%)

Query: 884  KKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVP 943
            K ++  + + + +L  + ++G+  ++I    K V+    Y   V  +R G+ G + +   
Sbjct: 537  KVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYH--VDFQRDGRSGTISVNTL 594

Query: 944  SLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSN-------FKLPTSLNLPGFV 996
                TA           G+  +LDLD E    Y+GG+P N        ++ T+L   G+V
Sbjct: 595  RTPYTAP----------GESEILDLDDE---LYLGGLPENKAGLVFPTEVWTALLNYGYV 641

Query: 997  GCLE---LATLNNDVISLYNFKHIYNMDPSTSVPCARDKLA-------FTQSRAASYFFD 1046
            GC+    +   + D+  +   +    + PS S   A+  L+         +     Y  D
Sbjct: 642  GCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCD 701

Query: 1047 --GSGY---AVVRDITRRGKFGQV------------TRFDIEVRTPADNGLILLMVNGSM 1089
              G+GY   +  R+ T     G +               D+ +R  +     +LM   S 
Sbjct: 702  CSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSR 761

Query: 1090 ----FFRLEMRNGYLHVFYDF-------GFSGGPVHLEDTLKKAQINDAKYHEISIIYHN 1138
                  RLE+  G + +  +          S GP   E       +ND ++H + ++   
Sbjct: 762  DSADTLRLELDAGRVKLTVNLDCIRINCNSSKGP---ETLFAGYNLNDNEWHTVRVV-RR 817

Query: 1139 DKKMILVVDRRHVKS--MDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMK 1196
             K + L VD +   +  M  +  ++ F +I  G     I+  R   + +P   NF G ++
Sbjct: 818  GKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETG-----IITERRYLSSVPS--NFIGHLQ 870

Query: 1197 GFQF---------QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFF 1247
               F         +  D +  E     G        ++I+    F  +S   ++  +  +
Sbjct: 871  SLTFNGMAYIDLCKNGDIDYCELNARFGFR------NIIADPVTFKTKSSYVALATLQAY 924

Query: 1248 DGFEGGFNFRTLQPNGLLFYYAS-GSDVFSISLDNGTV--IMDV---KGIKVQSVDKQYN 1301
                  F F+T   +GL+ Y +  G+D   + L  G +  + D+     +   S +K  N
Sbjct: 925  TSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLN 984

Query: 1302 DGLSHFVISSVSPTRYELIVDKSRV------GSKNPTKGKIEQTQASEKKFYFGGSPISA 1355
            D   H V+ S   +    +   +++      G++N             K+ Y     +  
Sbjct: 985  DNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVH 1044

Query: 1356 QYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKP 1415
                F GC+++     VD +  + D                + S  LF   +  +    P
Sbjct: 1045 AKEGFQGCLAS-----VDLNGRLPD----------------LISDALFCNGQIERGCEGP 1083

Query: 1416 KASQNKKGGKSKDA--PSWDPVALKL-------PERNTPRNSHCHLSNSPRAIEHAYQYG 1466
              +  +    ++      WD  +          P  N P  ++       +     Y++ 
Sbjct: 1084 STTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQI---TYKWP 1140

Query: 1467 GTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMF 1526
                     + L   F    + ++ +R  SS G+          D++ L +  G++   F
Sbjct: 1141 PNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGL---------GDYLELHIHQGKIGVKF 1191

Query: 1527 NVGHKKLKIR-SQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEAT-WKIKGP 1584
            NVG   + I  S    NDG +H V F R   +  L +D   V+E      + T +  +  
Sbjct: 1192 NVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQAT 1251

Query: 1585 IYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASI 1621
            I +GG   G+            F G LS L  NG  +
Sbjct: 1252 IIIGGKEQGQ-----------PFQGQLSGLYYNGLKV 1277



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 35/144 (24%), Positives = 68/144 (47%), Gaps = 7/144 (4%)

Query: 1485 KSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAH-GRLVYMFNV-GHKKLKIRSQEKYN 1542
            +S+ S +L+TRS+ G++ Y  D+   DF+ L L   GRL   F++   +   + +    N
Sbjct: 51   ESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVN 110

Query: 1543 DGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAP--GKAVKNVQ 1600
            DG WH V   R+  +  L ID +      +        +   +++GG+ P    A   + 
Sbjct: 111  DGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLT 170

Query: 1601 INSIYS---FSGCLSNLQLNGASI 1621
            + S+     F G + ++++N + +
Sbjct: 171  LASVREREPFKGWIRDVRVNSSQV 194



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 72/383 (18%), Positives = 142/383 (37%), Gaps = 67/383 (17%)

Query: 1484 AKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQE---K 1540
            +  + ++  +T   +G++ +    +  D++ L L +G +  + N+G    +   +    K
Sbjct: 304  SSDEITLSFKTLQRNGLMLHTG--KSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGK 361

Query: 1541 YNDGLWHDVIFIRE--RSSG------RLVIDGLRVLEESLPPTEATWKIKGP---IYLGG 1589
            +ND  WHDV   R   + SG       + +DG+     +   T+  + + G     Y+GG
Sbjct: 362  FNDNAWHDVKVTRNLRQHSGIGHAMVTISVDGILT---TTGYTQEDYTMLGSDDFFYVGG 418

Query: 1590 VA-----PGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFS-------------VT 1631
                   PG  V N       +F GCL  +      +       +               
Sbjct: 419  SPSTADLPGSPVSN-------NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAF 471

Query: 1632 PCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHS-------- 1683
             C          F T   ++ L + +N      I+F+ R    +G ++  H         
Sbjct: 472  KCENVATLDPITFETPESFISLPK-WNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDA 530

Query: 1684 -----VNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQL 1738
                 +  ++  + M +G + + ++ G          K+ + DG W+ +   RD     +
Sbjct: 531  KHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKK-VNDGEWYHVDFQRDGRSGTI 589

Query: 1739 DVDSEVNHVVGPLNPKPIDHREPVFVGGVPES---LLTP----RLAPSKPFTGCIRHFVI 1791
             V++       P   + +D  + +++GG+PE+   L+ P        +  + GCIR   I
Sbjct: 590  SVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFI 649

Query: 1792 DGHPVSFSKAALVSGAVSIN-SC 1813
            DG      + A V     +  SC
Sbjct: 650  DGQSKDIRQMAEVQSTAGVKPSC 672



 Score = 35.8 bits (81), Expect = 0.39
 Identities = 37/142 (26%), Positives = 61/142 (42%), Gaps = 21/142 (14%)

Query: 1060 GKFGQVTRF-----------DIEVRTPADNGLILLMVNGSMFFRLEM---RNGYLHVFYD 1105
            G  GQ TRF             +++T +  GL+L   +      LE+   R G L + + 
Sbjct: 35   GAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFS 94

Query: 1106 FGFSGGPVHLEDTLKKAQINDAKYHEISII--YHNDKKMILVVDRRHVKSMDNEKMKIPF 1163
              F   P  L   L    +ND  +H + I   + N    I  V+ + V+     +    F
Sbjct: 95   I-FCAEPATL---LADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVF 150

Query: 1164 TDIYIGGAPPEILQSRALRAHL 1185
            + +++GG PPE L++ AL+  L
Sbjct: 151  SGLFVGGLPPE-LRAAALKLTL 171


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,919,651
Number of Sequences: 37866
Number of extensions: 3237775
Number of successful extensions: 13867
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 123
Number of HSP's successfully gapped in prelim test: 674
Number of HSP's that attempted gapping in prelim test: 9629
Number of HSP's gapped (non-prelim): 2897
length of query: 1816
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1699
effective length of database: 13,817,196
effective search space: 23475416004
effective search space used: 23475416004
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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