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Search of human proteins with 157419124
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo
sapiens]
(1823 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 3670 0.0
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 3648 0.0
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 3648 0.0
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 828 0.0
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 801 0.0
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 796 0.0
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 756 0.0
gi|21264602 laminin alpha 5 [Homo sapiens] 690 0.0
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 418 e-116
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 417 e-116
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 391 e-108
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 169 3e-41
gi|143770880 laminin, beta 4 [Homo sapiens] 166 3e-40
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 159 2e-38
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 157 9e-38
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 145 5e-34
gi|157419130 laminin, alpha 4 isoform 3 precursor [Homo sapiens] 135 3e-31
gi|157419128 laminin, alpha 4 isoform 3 precursor [Homo sapiens] 135 3e-31
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 134 1e-30
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 132 3e-30
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 132 4e-30
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 128 6e-29
gi|219842266 usherin isoform B [Homo sapiens] 106 2e-22
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 103 2e-21
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 103 2e-21
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 103 2e-21
gi|93204871 netrin 4 [Homo sapiens] 100 1e-20
gi|219842259 usherin isoform A [Homo sapiens] 92 4e-18
gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens] 87 1e-16
gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens] 87 1e-16
>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
Length = 1823
Score = 3670 bits (9518), Expect = 0.0
Identities = 1823/1823 (100%), Positives = 1823/1823 (100%)
Query: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
Sbjct: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
Query: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
Sbjct: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
Sbjct: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
Query: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
Sbjct: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
Query: 241 CNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDALRLAALSIEEGKSGVLS 300
CNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDALRLAALSIEEGKSGVLS
Sbjct: 241 CNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDALRLAALSIEEGKSGVLS 300
Query: 301 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE 360
VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE
Sbjct: 301 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE 360
Query: 361 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL 420
NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL
Sbjct: 361 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL 420
Query: 421 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD 480
VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD
Sbjct: 421 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD 480
Query: 481 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS 540
YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS
Sbjct: 481 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS 540
Query: 541 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 600
LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE
Sbjct: 541 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 600
Query: 601 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT 660
ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT
Sbjct: 601 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT 660
Query: 661 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ 720
QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ
Sbjct: 661 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ 720
Query: 721 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS 780
AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS
Sbjct: 721 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS 780
Query: 781 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG 840
ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG
Sbjct: 781 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG 840
Query: 841 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK 900
QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK
Sbjct: 841 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK 900
Query: 901 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF 960
NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
Sbjct: 901 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF 960
Query: 961 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN 1020
IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
Sbjct: 961 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN 1020
Query: 1021 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR 1080
FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
Sbjct: 1021 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR 1080
Query: 1081 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS 1140
TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
Sbjct: 1081 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS 1140
Query: 1141 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG 1200
IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG
Sbjct: 1141 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG 1200
Query: 1201 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG 1260
CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG
Sbjct: 1201 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG 1260
Query: 1261 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS 1320
FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS
Sbjct: 1261 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS 1320
Query: 1321 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD 1380
PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD
Sbjct: 1321 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD 1380
Query: 1381 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD 1440
RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD
Sbjct: 1381 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD 1440
Query: 1441 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR 1500
PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR
Sbjct: 1441 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR 1500
Query: 1501 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR 1560
TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR
Sbjct: 1501 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR 1560
Query: 1561 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN 1620
ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN
Sbjct: 1561 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN 1620
Query: 1621 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS 1680
LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS
Sbjct: 1621 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS 1680
Query: 1681 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS 1740
SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS
Sbjct: 1681 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS 1740
Query: 1741 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG 1800
NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG
Sbjct: 1741 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG 1800
Query: 1801 HPVSFSKAALVSGAVSINSCPAA 1823
HPVSFSKAALVSGAVSINSCPAA
Sbjct: 1801 HPVSFSKAALVSGAVSINSCPAA 1823
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 3648 bits (9460), Expect = 0.0
Identities = 1816/1823 (99%), Positives = 1816/1823 (99%), Gaps = 7/1823 (0%)
Query: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
Sbjct: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
Query: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
Sbjct: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
Sbjct: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
Query: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
Sbjct: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
Query: 241 CNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDALRLAALSIEEGKSGVLS 300
CNCGGGPCDSVTGECLEEGFEPPTG CDKCVWDLTDALRLAALSIEEGKSGVLS
Sbjct: 241 CNCGGGPCDSVTGECLEEGFEPPTG-------CDKCVWDLTDALRLAALSIEEGKSGVLS 293
Query: 301 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE 360
VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE
Sbjct: 294 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE 353
Query: 361 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL 420
NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL
Sbjct: 354 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL 413
Query: 421 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD 480
VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD
Sbjct: 414 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD 473
Query: 481 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS 540
YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS
Sbjct: 474 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS 533
Query: 541 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 600
LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE
Sbjct: 534 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 593
Query: 601 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT 660
ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT
Sbjct: 594 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT 653
Query: 661 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ 720
QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ
Sbjct: 654 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ 713
Query: 721 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS 780
AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS
Sbjct: 714 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS 773
Query: 781 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG 840
ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG
Sbjct: 774 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG 833
Query: 841 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK 900
QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK
Sbjct: 834 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK 893
Query: 901 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF 960
NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
Sbjct: 894 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF 953
Query: 961 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN 1020
IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
Sbjct: 954 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN 1013
Query: 1021 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR 1080
FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
Sbjct: 1014 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR 1073
Query: 1081 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS 1140
TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
Sbjct: 1074 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS 1133
Query: 1141 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG 1200
IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG
Sbjct: 1134 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG 1193
Query: 1201 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG 1260
CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG
Sbjct: 1194 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG 1253
Query: 1261 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS 1320
FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS
Sbjct: 1254 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS 1313
Query: 1321 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD 1380
PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD
Sbjct: 1314 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD 1373
Query: 1381 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD 1440
RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD
Sbjct: 1374 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD 1433
Query: 1441 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR 1500
PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR
Sbjct: 1434 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR 1493
Query: 1501 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR 1560
TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR
Sbjct: 1494 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR 1553
Query: 1561 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN 1620
ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN
Sbjct: 1554 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN 1613
Query: 1621 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS 1680
LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS
Sbjct: 1614 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS 1673
Query: 1681 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS 1740
SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS
Sbjct: 1674 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS 1733
Query: 1741 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG 1800
NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG
Sbjct: 1734 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG 1793
Query: 1801 HPVSFSKAALVSGAVSINSCPAA 1823
HPVSFSKAALVSGAVSINSCPAA
Sbjct: 1794 HPVSFSKAALVSGAVSINSCPAA 1816
>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 3648 bits (9460), Expect = 0.0
Identities = 1816/1823 (99%), Positives = 1816/1823 (99%), Gaps = 7/1823 (0%)
Query: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
Sbjct: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
Query: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
Sbjct: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
Sbjct: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
Query: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
Sbjct: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
Query: 241 CNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDALRLAALSIEEGKSGVLS 300
CNCGGGPCDSVTGECLEEGFEPPTG CDKCVWDLTDALRLAALSIEEGKSGVLS
Sbjct: 241 CNCGGGPCDSVTGECLEEGFEPPTG-------CDKCVWDLTDALRLAALSIEEGKSGVLS 293
Query: 301 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE 360
VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE
Sbjct: 294 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE 353
Query: 361 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL 420
NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL
Sbjct: 354 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL 413
Query: 421 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD 480
VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD
Sbjct: 414 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD 473
Query: 481 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS 540
YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS
Sbjct: 474 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS 533
Query: 541 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 600
LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE
Sbjct: 534 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 593
Query: 601 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT 660
ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT
Sbjct: 594 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT 653
Query: 661 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ 720
QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ
Sbjct: 654 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ 713
Query: 721 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS 780
AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS
Sbjct: 714 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS 773
Query: 781 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG 840
ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG
Sbjct: 774 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG 833
Query: 841 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK 900
QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK
Sbjct: 834 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK 893
Query: 901 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF 960
NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
Sbjct: 894 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF 953
Query: 961 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN 1020
IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
Sbjct: 954 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN 1013
Query: 1021 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR 1080
FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
Sbjct: 1014 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR 1073
Query: 1081 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS 1140
TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
Sbjct: 1074 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS 1133
Query: 1141 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG 1200
IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG
Sbjct: 1134 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG 1193
Query: 1201 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG 1260
CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG
Sbjct: 1194 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG 1253
Query: 1261 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS 1320
FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS
Sbjct: 1254 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS 1313
Query: 1321 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD 1380
PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD
Sbjct: 1314 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD 1373
Query: 1381 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD 1440
RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD
Sbjct: 1374 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD 1433
Query: 1441 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR 1500
PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR
Sbjct: 1434 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR 1493
Query: 1501 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR 1560
TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR
Sbjct: 1494 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR 1553
Query: 1561 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN 1620
ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN
Sbjct: 1554 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN 1613
Query: 1621 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS 1680
LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS
Sbjct: 1614 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS 1673
Query: 1681 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS 1740
SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS
Sbjct: 1674 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS 1733
Query: 1741 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG 1800
NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG
Sbjct: 1734 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG 1793
Query: 1801 HPVSFSKAALVSGAVSINSCPAA 1823
HPVSFSKAALVSGAVSINSCPAA
Sbjct: 1794 HPVSFSKAALVSGAVSINSCPAA 1816
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 828 bits (2140), Expect = 0.0
Identities = 560/1822 (30%), Positives = 892/1822 (48%), Gaps = 162/1822 (8%)
Query: 40 SAVGRQDPPETSEPRVALG----RLPPA-----AEKCNAGFFHT----LSGECVPCDCNG 86
S VG ++ +T R+AL PPA + C+ G++ +G CVPC+CNG
Sbjct: 1632 SEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNG 1691
Query: 87 NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESC 146
+SN+C DGSG CV+CQ NT GEHCE+C +GY G+++ G+ C+ CPC PH +FA C
Sbjct: 1692 HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS---CRACPC--PHTNSFATGC 1746
Query: 147 YRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVT 206
G VRC C Y G CERCAPGY+GNP G +C+ C C+ N C +T
Sbjct: 1747 VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLT 1802
Query: 207 GQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGM 266
G C N P DS E
Sbjct: 1803 GDCIN---------------------------------QEPKDSSPAE------------ 1817
Query: 267 DCPTISCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLS 326
+C CD CV L + L + KS + +S+ A + + L+ +L
Sbjct: 1818 ECD--DCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLL 1875
Query: 327 ERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVE 386
+ + +I E + L + E L EK SRK Q + N+ ++ +
Sbjct: 1876 NYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN-------NNVNRATQ 1928
Query: 387 QAHDMRDKIQEINNKMLYY--------GEEHELSPKEISEKLVLAQKMLEEIRSRQPFFT 438
A ++ KI+ + + GE + + + S + AQ+M+ E+R+R
Sbjct: 1929 SAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRN---F 1985
Query: 439 QRELVDEEAD--EAYELLSQAESWQRLH-NETRTLFPVVLEQLDDYNAKLSDLQEALDQA 495
+ L + EAD E+ LL++ +WQ+ H E L + + L++Y AKLSDL+ L +A
Sbjct: 1986 GKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEA 2045
Query: 496 LNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDII 555
+ A +N+ ++Q + + L+T+ SL + L ++
Sbjct: 2046 AAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQ 2105
Query: 556 KNASGIYAEIDGAKSELQVKLSNLSNLS--HDLVQEAIDHAQDLQQEANELSRKLHSSDM 613
K + A ++ A+ EL K+ LS + LV+EA HA+ LQ+ A +L ++
Sbjct: 2106 KEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASG 2165
Query: 614 NGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAV--SGIDTQIIYHKDESEN 671
+ LV+ A+DA+ YENI+N + A + A A + ++ V + + S+
Sbjct: 2166 DELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDK 2225
Query: 672 LLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRL 731
LLN+A+ Q K + A+ + + + +K + T L+ L +RGD +
Sbjct: 2226 LLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMI 2285
Query: 732 GQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEV 791
++ + +AN T EV P+ ++ + + A+ A ++V LT
Sbjct: 2286 SSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNK 2345
Query: 792 VPQLLDQLRTVEQK-RPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRT 850
+P L ++ ++ Q+ P N+S ++ RIRELI Q R ASK+ V M F+G+S VEV
Sbjct: 2346 LPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPN 2405
Query: 851 SMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNL 910
++DLK +TSLSL+++ P R E T + F++YLG+K+A ++Y+G+A+ + L VYNL
Sbjct: 2406 DLEDLKGYTSLSLFLQRPNSR-ENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNL 2464
Query: 911 GTKDVEIPLDSKPVSS--WPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSG 968
G ++ E+ +D S A VK +R+ + ++ T + SS E + +
Sbjct: 2465 GDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRN 2524
Query: 969 DDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMD 1028
++LL+LDPE+ VFYVGG P +FKLP+ L+ P + GC+EL LN +V+SLYNFK +N++
Sbjct: 2525 SNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLN 2584
Query: 1029 PSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLI 1088
+ PC R K + +F+G+GYA V + F ++T D GL+
Sbjct: 2585 TTEVEPCRRRK-----EESDKNYFEGTGYARV----PTQPHAPIPTFGQTIQTTVDRGLL 2635
Query: 1089 LLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQ-----INDAKYHEISI-I 1142
NG F L + +G L V Y L L K + IN+ + H I I I
Sbjct: 2636 FFAENGDRFISLNIEDGKLMVRY---------KLNSELPKERGVGDAINNGRDHSIQIKI 2686
Query: 1143 YHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCM 1202
K+M + VD ++ +D E F+ Y+GG P I + + FRGCM
Sbjct: 2687 GKLQKRMWINVDVQNT-IIDGE--VFDFSTYYLGGIPIAIRERFNISTPA-----FRGCM 2738
Query: 1203 KGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFN-GQSFIASIQKISFFDGFEGGF 1261
K KK ++ +T+GV C ED + R A F+ G + + D + F
Sbjct: 2739 KNL---KKTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASF 2795
Query: 1262 NFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDV--KGIKVQSVDKQYNDGLSHFVISSV 1319
F+T QP+G+L + + + ++L++G + + G + + Y DGL H+V
Sbjct: 2796 GFQTFQPSGILLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVIS 2855
Query: 1320 SPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRV 1379
+ L++D + + +++ +S + GGS NF GCISN + R+
Sbjct: 2856 DNSGLRLLIDDQLLRNSK----RLKHISSSRQSLRLGGS-------NFEGCISNVFVQRL 2904
Query: 1380 DRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSW 1439
EV D + K SL C + P +L K +K K + + +D P
Sbjct: 2905 SLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVA 2962
Query: 1440 DPVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRL 1499
P ++K+ + C +A A Q+G S F+ + +SQF++ +
Sbjct: 2963 SPRSVKVWQ------DACSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDM 3016
Query: 1500 RTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFI 1559
+T SS G++F+ +N FM L+L+ GRLV+ KKL+I+S+EK NDG WH V+F
Sbjct: 3017 QTTSSRGLVFHTG--TKNSFMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFG 3074
Query: 1560 RERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLS 1619
+ GRLV+DGLR E SL P +T I+ P+YLG GK K++ N SF GCL
Sbjct: 3075 HDGEKGRLVVDGLRAREGSL-PGNSTISIRAPVYLGSPPSGKP-KSLPTN---SFVGCLK 3129
Query: 1620 NLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPR 1679
N QL+ + + S +F V+ C GP+E G YFS EGG+VVL S +G +F++ F +RPR
Sbjct: 3130 NFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPR 3189
Query: 1680 SSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRD 1739
S +G L+H S G++L V+++ G+V +++G STSVTPKQSLCDG+WH + V
Sbjct: 3190 SLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIK 3249
Query: 1740 SNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVID 1799
+++ L++D++ ++ G + P +EP+ +GG P +L T R+ K F GC+R+ ++
Sbjct: 3250 QHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVN 3309
Query: 1800 GHPVSFSKAALVSGAVSINSCP 1821
PV ++A V G VS+N CP
Sbjct: 3310 HIPVPVTEALEVQGPVSLNGCP 3331
Score = 105 bits (263), Expect = 3e-22
Identities = 76/244 (31%), Positives = 102/244 (41%), Gaps = 65/244 (26%)
Query: 76 SGECVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGY 117
S EC C+C+G+++ C G G C++CQ NT G +CE+C GY
Sbjct: 350 SHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGY 409
Query: 118 I---GDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
G + AP C PC C H A+ C + G+ RC C N+ G NCE+CA GYY
Sbjct: 410 YRPYGVPV-DAPDGCIPCSCDPEH----ADGC--EQGSGRCHCKPNFHGDNCEKCAIGYY 462
Query: 175 GNPLL----------------IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTG 218
P + K CDC+ ++ E CD G+C C G
Sbjct: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLE---GVLPEICD-AHGRCL-CRPGVEG 517
Query: 219 FKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGMDCPTISC 273
+C+ C G+Y C C C PC SVTG+C E TG C
Sbjct: 518 PRCDTCRSGFYS----FPICQACWCSALGSYQMPCSSVTGQC--ECRPGVTGQ-----RC 566
Query: 274 DKCV 277
D+C+
Sbjct: 567 DRCL 570
Score = 80.1 bits (196), Expect = 2e-14
Identities = 58/183 (31%), Positives = 79/183 (43%), Gaps = 41/183 (22%)
Query: 74 TLSGECVPCDCNGNSNECLDGSG---YCVHCQRNTTGEHCEKCLDGYIGDSIRGA----P 126
++ G+CV CNG++ C + + CQ +T GE C++C GY R A
Sbjct: 294 SIGGQCV---CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQS 350
Query: 127 QFCQPCPCPLPHLANFAESCY-----------------RKNGAVRCICNENYAGPNCERC 169
C+ C C A +CY G V C N AG NCE+C
Sbjct: 351 HECEACNC-----HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQC 405
Query: 170 APGY---YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226
A GY YG P+ C C C DP + C++ +G+C +C N G CE+CA
Sbjct: 406 AKGYYRPYGVPVDAPDGCIPCSC----DPEHA-DGCEQGSGRC-HCKPNFHGDNCEKCAI 459
Query: 227 GYY 229
GYY
Sbjct: 460 GYY 462
Score = 70.5 bits (171), Expect = 1e-11
Identities = 63/232 (27%), Positives = 87/232 (37%), Gaps = 25/232 (10%)
Query: 18 SAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSG 77
++A S A A P + + A G PE + + +C G H
Sbjct: 1250 NSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATG--HYGFP 1307
Query: 78 ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKC-LDGYIGDSIRGAPQFCQPCPCPL 136
C PC C C + +G C C T CE C + + G C+ C C
Sbjct: 1308 RCKPCSCGRRL--CEEMTGQC-RCPPRTVRPQCEVCETHSFSFHPMAG----CEGCNCSR 1360
Query: 137 PHLANFA-ESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCS-GNSD 194
A C R +G +C C G C+RCA G+Y P C C+C+ ++
Sbjct: 1361 RGTIEAAMPECDRDSG--QCRCKPRITGRQCDRCASGFYRFP-----ECVPCNCNRDGTE 1413
Query: 195 PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG-YYGDARIAKNCAVCNCGG 245
P + CD TG C C N G +C C G ++ D K C C C G
Sbjct: 1414 PGV----CDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKGCTSCFCFG 1460
Score = 67.4 bits (163), Expect = 1e-10
Identities = 54/197 (27%), Positives = 68/197 (34%), Gaps = 59/197 (29%)
Query: 105 TTGEHCEKCLDGYIGDSIRGA-PQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAG 163
T C+ + +GA P C P PH C + G +C C N G
Sbjct: 1243 TASRFCKNSARSLVAFYHKGALPCECHPTGATGPH-------CSPEGG--QCPCQPNVIG 1293
Query: 164 PNCERCAPGYYG----NPLLIG-----------------------------------STC 184
C RCA G+YG P G + C
Sbjct: 1294 RQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGC 1353
Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244
+ C+CS +CD +GQCR C TG +C+RCA G+Y C CNC
Sbjct: 1354 EGCNCSRRGTIEAAMPECDRDSGQCR-CKPRITGRQCDRCASGFYR----FPECVPCNCN 1408
Query: 245 -----GGPCDSVTGECL 256
G CD TG CL
Sbjct: 1409 RDGTEPGVCDPGTGACL 1425
Score = 62.4 bits (150), Expect = 4e-09
Identities = 51/202 (25%), Positives = 75/202 (37%), Gaps = 24/202 (11%)
Query: 62 PAAEKCNAGFFHTLSGECVPCDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDG-YIG 119
P + C +GF+ + C G+ C +G C C+ TG+ C++CL G Y
Sbjct: 518 PRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDF 576
Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
+G+ C P +L C C + GP C RC Y+
Sbjct: 577 PHCQGSSSACDPAGTINSNLGY-------------CQCKLHVEGPTCSRCKLLYWNLDKE 623
Query: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNC 238
S C +C C + E C + G C +C + G C+ C GY+ + C
Sbjct: 624 NPSGCSECKCHKAGTVSGTGE-CRQGDGDC-HCKSHVGGDSCDTCEDGYFALEKSNYFGC 681
Query: 239 AVCNC--GG---GPCDSVTGEC 255
C C GG C +G C
Sbjct: 682 QGCQCDIGGALSSMCSGPSGVC 703
Score = 58.2 bits (139), Expect = 7e-08
Identities = 36/126 (28%), Positives = 51/126 (40%), Gaps = 24/126 (19%)
Query: 154 RCICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNLIFEDCD 203
RC C + G C+RC GY + C+ C+C G++ DP++ +
Sbjct: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQAS 377
Query: 204 EVT-------GQCRNCLRNTTGFKCERCAPGYYGDARI----AKNCAVCNCG---GGPCD 249
T G C NC NT G CE+CA GYY + C C+C C+
Sbjct: 378 LNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCE 437
Query: 250 SVTGEC 255
+G C
Sbjct: 438 QGSGRC 443
Score = 51.6 bits (122), Expect = 7e-06
Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 13/102 (12%)
Query: 79 CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF-CQPC 132
C C C+ + EC G G C HC+ + G+ C+ C DGY ++ + F CQ C
Sbjct: 628 CSECKCHKAGTVSGTGECRQGDGDC-HCKSHVGGDSCDTCEDGYF--ALEKSNYFGCQGC 684
Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
C + + C +G C C E+ G C+R YY
Sbjct: 685 QCDIG--GALSSMCSGPSGV--CQCREHVVGKVCQRPENNYY 722
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 801 bits (2069), Expect = 0.0
Identities = 548/1812 (30%), Positives = 870/1812 (48%), Gaps = 198/1812 (10%)
Query: 40 SAVGRQDPPETSEPRVALG----RLPPA-----AEKCNAGFFHT----LSGECVPCDCNG 86
S VG ++ +T R+AL PPA + C+ G++ +G CVPC+CNG
Sbjct: 1632 SEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNG 1691
Query: 87 NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESC 146
+SN+C DGSG CV+CQ NT GEHCE+C +GY G+++ G+ C+ CPC PH +FA C
Sbjct: 1692 HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS---CRACPC--PHTNSFATGC 1746
Query: 147 YRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVT 206
G VRC C Y G CERCAPGY+GNP G +C+ C C+ N C +T
Sbjct: 1747 VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLT 1802
Query: 207 GQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGM 266
G C N P DS E
Sbjct: 1803 GDCIN---------------------------------QEPKDSSPAE------------ 1817
Query: 267 DCPTISCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLS 326
+C CD CV L + L + KS + +S+ A + + L+ +L
Sbjct: 1818 ECD--DCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLL 1875
Query: 327 ERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVE 386
+ + +I E + L + E L EK SRK Q + + +N A+Q
Sbjct: 1876 NYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN----NNVNRATQ--- 1928
Query: 387 QAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEE 446
S KE+ K+ + ++ +
Sbjct: 1929 -------------------------SAKELDVKI---KNVIRNV---------------- 1944
Query: 447 ADEAYELLSQAESWQRLH-NETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDM 505
+L++ +WQ+ H E L + + L++Y AKLSDL+ L +A + A +
Sbjct: 1945 -----HMLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGL 1999
Query: 506 NRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEI 565
N+ ++Q + + L+T+ SL + L ++ K + A +
Sbjct: 2000 NQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASL 2059
Query: 566 DGAKSELQVKLSNLSNLS--HDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDA 623
+ A+ EL K+ LS + LV+EA HA+ LQ+ A +L ++ + LV+ A+DA
Sbjct: 2060 NEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDA 2119
Query: 624 SNVYENIVNYVSEANETAEFALNTTDRIYDAV--SGIDTQIIYHKDESENLLNQARELQA 681
+ YENI+N + A + A A + ++ V + + S+ LLN+A+ Q
Sbjct: 2120 ATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQK 2179
Query: 682 KAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEA 741
K + A+ + + + +K + T L+ L +RGD + ++ + +A
Sbjct: 2180 KLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKA 2239
Query: 742 NRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRT 801
N T EV P+ ++ + + A+ A ++V LT +P L ++ +
Sbjct: 2240 NDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIES 2299
Query: 802 VEQK-RPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTS 860
+ Q+ P N+S ++ RIRELI Q R ASK+ V M F+G+S VEV ++DLK +TS
Sbjct: 2300 INQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTS 2359
Query: 861 LSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLD 920
LSL+++ P R E T + F++YLG+K+A ++Y+G+A+ + L VYNLG ++ E+ +D
Sbjct: 2360 LSLFLQRPNSR-ENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVD 2418
Query: 921 SKPVSS--WPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPE 978
S A VK +R+ + ++ T + SS E + + ++LL+LDPE
Sbjct: 2419 QILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPE 2478
Query: 979 DTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARD 1038
+ VFYVGG P +FKLP+ L+ P + GC+EL LN +V+SLYNFK +N++ + PC R
Sbjct: 2479 NVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRR 2538
Query: 1039 KLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFF 1098
K + +F+G+GYA V + F ++T D GL+ NG F
Sbjct: 2539 K-----EESDKNYFEGTGYARV----PTQPHAPIPTFGQTIQTTVDRGLLFFAENGDRFI 2589
Query: 1099 RLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQ-----INDAKYHEISI-IYHNDKKMILV 1152
L + +G L V Y L L K + IN+ + H I I I K+M +
Sbjct: 2590 SLNIEDGKLMVRY---------KLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWIN 2640
Query: 1153 VDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDF 1212
VD ++ +D E F+ Y+GG P I + + FRGCMK KK
Sbjct: 2641 VDVQNT-IIDGE--VFDFSTYYLGGIPIAIRERFNISTPA-----FRGCMKNL---KKTS 2689
Query: 1213 NLLEQTETLGVGYGCPEDSLISRRAYFN-GQSFIASIQKISFFDGFEGGFNFRTLQPNGL 1271
++ +T+GV C ED + R A F+ G + + D + F F+T QP+G+
Sbjct: 2690 GVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGI 2749
Query: 1272 LFYYASGSDVFSISLDNGTVIMDV--KGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVD 1329
L + + + ++L++G + + G + + Y DGL H+V + L++D
Sbjct: 2750 LLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLID 2809
Query: 1330 KSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQ 1389
+ + +++ +S + GGS NF GCISN + R+ EV D
Sbjct: 2810 DQLLRNSK----RLKHISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEVLDLT 2858
Query: 1390 RYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPER 1449
+ K SL C + P +L K +K K + + +D P P ++K+ +
Sbjct: 2859 SNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKVWQ- 2915
Query: 1450 NTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIF 1509
C +A A Q+G S F+ + +SQF++ ++T SS G++F
Sbjct: 2916 -----DACSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVF 2970
Query: 1510 YVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVI 1569
+ +N FM L+L+ GRLV+ KKL+I+S+EK NDG WH V+F + GRLV+
Sbjct: 2971 HTG--TKNSFMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVV 3028
Query: 1570 DGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASIT 1629
DGLR E SL P +T I+ P+YLG GK K++ N SF GCL N QL+ +
Sbjct: 3029 DGLRAREGSL-PGNSTISIRAPVYLGSPPSGKP-KSLPTN---SFVGCLKNFQLDSKPLY 3083
Query: 1630 SASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGH 1689
+ S +F V+ C GP+E G YFS EGG+VVL S +G +F++ F +RPRS +G L+H
Sbjct: 3084 TPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIG 3143
Query: 1690 SVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDS 1749
S G++L V+++ G+V +++G STSVTPKQSLCDG+WH + V +++ L++D+
Sbjct: 3144 SQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDT 3203
Query: 1750 EVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAA 1809
+ ++ G + P +EP+ +GG P +L T R+ K F GC+R+ ++ PV ++A
Sbjct: 3204 DSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEAL 3263
Query: 1810 LVSGAVSINSCP 1821
V G VS+N CP
Sbjct: 3264 EVQGPVSLNGCP 3275
Score = 105 bits (263), Expect = 3e-22
Identities = 76/244 (31%), Positives = 102/244 (41%), Gaps = 65/244 (26%)
Query: 76 SGECVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGY 117
S EC C+C+G+++ C G G C++CQ NT G +CE+C GY
Sbjct: 350 SHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGY 409
Query: 118 I---GDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
G + AP C PC C H A+ C + G+ RC C N+ G NCE+CA GYY
Sbjct: 410 YRPYGVPV-DAPDGCIPCSCDPEH----ADGC--EQGSGRCHCKPNFHGDNCEKCAIGYY 462
Query: 175 GNPLL----------------IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTG 218
P + K CDC+ ++ E CD G+C C G
Sbjct: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLE---GVLPEICD-AHGRCL-CRPGVEG 517
Query: 219 FKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGMDCPTISC 273
+C+ C G+Y C C C PC SVTG+C E TG C
Sbjct: 518 PRCDTCRSGFYS----FPICQACWCSALGSYQMPCSSVTGQC--ECRPGVTGQ-----RC 566
Query: 274 DKCV 277
D+C+
Sbjct: 567 DRCL 570
Score = 80.1 bits (196), Expect = 2e-14
Identities = 58/183 (31%), Positives = 79/183 (43%), Gaps = 41/183 (22%)
Query: 74 TLSGECVPCDCNGNSNECLDGSG---YCVHCQRNTTGEHCEKCLDGYIGDSIRGA----P 126
++ G+CV CNG++ C + + CQ +T GE C++C GY R A
Sbjct: 294 SIGGQCV---CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQS 350
Query: 127 QFCQPCPCPLPHLANFAESCY-----------------RKNGAVRCICNENYAGPNCERC 169
C+ C C A +CY G V C N AG NCE+C
Sbjct: 351 HECEACNC-----HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQC 405
Query: 170 APGY---YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226
A GY YG P+ C C C DP + C++ +G+C +C N G CE+CA
Sbjct: 406 AKGYYRPYGVPVDAPDGCIPCSC----DPEHA-DGCEQGSGRC-HCKPNFHGDNCEKCAI 459
Query: 227 GYY 229
GYY
Sbjct: 460 GYY 462
Score = 70.5 bits (171), Expect = 1e-11
Identities = 63/232 (27%), Positives = 87/232 (37%), Gaps = 25/232 (10%)
Query: 18 SAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSG 77
++A S A A P + + A G PE + + +C G H
Sbjct: 1250 NSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATG--HYGFP 1307
Query: 78 ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKC-LDGYIGDSIRGAPQFCQPCPCPL 136
C PC C C + +G C C T CE C + + G C+ C C
Sbjct: 1308 RCKPCSCGRRL--CEEMTGQC-RCPPRTVRPQCEVCETHSFSFHPMAG----CEGCNCSR 1360
Query: 137 PHLANFA-ESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCS-GNSD 194
A C R +G +C C G C+RCA G+Y P C C+C+ ++
Sbjct: 1361 RGTIEAAMPECDRDSG--QCRCKPRITGRQCDRCASGFYRFP-----ECVPCNCNRDGTE 1413
Query: 195 PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG-YYGDARIAKNCAVCNCGG 245
P + CD TG C C N G +C C G ++ D K C C C G
Sbjct: 1414 PGV----CDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKGCTSCFCFG 1460
Score = 67.4 bits (163), Expect = 1e-10
Identities = 54/197 (27%), Positives = 68/197 (34%), Gaps = 59/197 (29%)
Query: 105 TTGEHCEKCLDGYIGDSIRGA-PQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAG 163
T C+ + +GA P C P PH C + G +C C N G
Sbjct: 1243 TASRFCKNSARSLVAFYHKGALPCECHPTGATGPH-------CSPEGG--QCPCQPNVIG 1293
Query: 164 PNCERCAPGYYG----NPLLIG-----------------------------------STC 184
C RCA G+YG P G + C
Sbjct: 1294 RQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGC 1353
Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244
+ C+CS +CD +GQCR C TG +C+RCA G+Y C CNC
Sbjct: 1354 EGCNCSRRGTIEAAMPECDRDSGQCR-CKPRITGRQCDRCASGFYR----FPECVPCNCN 1408
Query: 245 -----GGPCDSVTGECL 256
G CD TG CL
Sbjct: 1409 RDGTEPGVCDPGTGACL 1425
Score = 62.4 bits (150), Expect = 4e-09
Identities = 51/202 (25%), Positives = 75/202 (37%), Gaps = 24/202 (11%)
Query: 62 PAAEKCNAGFFHTLSGECVPCDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDG-YIG 119
P + C +GF+ + C G+ C +G C C+ TG+ C++CL G Y
Sbjct: 518 PRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDF 576
Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
+G+ C P +L C C + GP C RC Y+
Sbjct: 577 PHCQGSSSACDPAGTINSNLGY-------------CQCKLHVEGPTCSRCKLLYWNLDKE 623
Query: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNC 238
S C +C C + E C + G C +C + G C+ C GY+ + C
Sbjct: 624 NPSGCSECKCHKAGTVSGTGE-CRQGDGDC-HCKSHVGGDSCDTCEDGYFALEKSNYFGC 681
Query: 239 AVCNC--GG---GPCDSVTGEC 255
C C GG C +G C
Sbjct: 682 QGCQCDIGGALSSMCSGPSGVC 703
Score = 58.2 bits (139), Expect = 7e-08
Identities = 36/126 (28%), Positives = 51/126 (40%), Gaps = 24/126 (19%)
Query: 154 RCICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNLIFEDCD 203
RC C + G C+RC GY + C+ C+C G++ DP++ +
Sbjct: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQAS 377
Query: 204 EVT-------GQCRNCLRNTTGFKCERCAPGYYGDARI----AKNCAVCNCG---GGPCD 249
T G C NC NT G CE+CA GYY + C C+C C+
Sbjct: 378 LNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCE 437
Query: 250 SVTGEC 255
+G C
Sbjct: 438 QGSGRC 443
Score = 51.6 bits (122), Expect = 7e-06
Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 13/102 (12%)
Query: 79 CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF-CQPC 132
C C C+ + EC G G C HC+ + G+ C+ C DGY ++ + F CQ C
Sbjct: 628 CSECKCHKAGTVSGTGECRQGDGDC-HCKSHVGGDSCDTCEDGYF--ALEKSNYFGCQGC 684
Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
C + + C +G C C E+ G C+R YY
Sbjct: 685 QCDIG--GALSSMCSGPSGV--CQCREHVVGKVCQRPENNYY 722
>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
Length = 1668
Score = 796 bits (2056), Expect = 0.0
Identities = 542/1796 (30%), Positives = 864/1796 (48%), Gaps = 190/1796 (10%)
Query: 47 PPETSEPRVALGRLPPAAEKCNAGFFHT----LSGECVPCDCNGNSNECLDGSGYCVHCQ 102
PP S+ + + P+ + C+ G++ +G CVPC+CNG+SN+C DGSG CV+CQ
Sbjct: 40 PPGQSQLQASYVEFRPS-QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQ 98
Query: 103 RNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYA 162
NT GEHCE+C +GY G+++ G+ C+ CPC PH +FA C G VRC C Y
Sbjct: 99 HNTAGEHCERCQEGYYGNAVHGS---CRACPC--PHTNSFATGCVVNGGDVRCSCKAGYT 153
Query: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCE 222
G CERCAPGY+GNP G +C+ C C+ N C +TG C N
Sbjct: 154 GTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLTGDCIN----------- 198
Query: 223 RCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTD 282
P DS E +C CD CV L +
Sbjct: 199 ----------------------QEPKDSSPAE------------ECD--DCDSCVMTLLN 222
Query: 283 ALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNA 342
L + KS + +S+ A + + L+ +L + + +I
Sbjct: 223 DLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGL 282
Query: 343 ENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKM 402
E + L + E L EK SRK Q + + +N A+Q
Sbjct: 283 ERELTDLNQEFETLQEKAQVNSRKAQTLN----NNVNRATQ------------------- 319
Query: 403 LYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQR 462
S KE+ K+ + ++ + +L++ +WQ+
Sbjct: 320 ---------SAKELDVKI---KNVIRNV---------------------HMLNRIRTWQK 346
Query: 463 LH-NETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQE 521
H E L + + L++Y AKLSDL+ L +A + A +N+ ++Q +
Sbjct: 347 THQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVK 406
Query: 522 RVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSN 581
+ L+T+ SL + L ++ K + A ++ A+ EL K+ LS
Sbjct: 407 EINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSR 466
Query: 582 LS--HDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANE 639
+ LV+EA HA+ LQ+ A +L ++ + LV+ A+DA+ YENI+N + A +
Sbjct: 467 SAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAED 526
Query: 640 TAEFALNTTDRIYDAV--SGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRR 697
A A + ++ V + + S+ LLN+A+ Q K + A+ + +
Sbjct: 527 AANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQT 586
Query: 698 VGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMAN 757
+ +K + T L+ L +RGD + ++ + +AN T EV P+
Sbjct: 587 LNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQT 646
Query: 758 NLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQK-RPASNVSASIQ 816
++ + + A+ A ++V LT +P L ++ ++ Q+ P N+S ++
Sbjct: 647 DVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMD 706
Query: 817 RIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTE 876
RIRELI Q R ASK+ V M F+G+S VEV ++DLK +TSLSL+++ P R E
Sbjct: 707 RIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSR-ENGG 765
Query: 877 TADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSS--WPAYFSIV 934
T + F++YLG+K+A ++Y+G+A+ + L VYNLG ++ E+ +D S A V
Sbjct: 766 TENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRV 825
Query: 935 KIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLP 994
K +R+ + ++ T + SS E + + ++LL+LDPE+ VFYVGG P +FKLP
Sbjct: 826 KFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLP 885
Query: 995 TSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDG 1054
+ L+ P + GC+EL LN +V+SLYNFK +N++ + PC R K + +F+G
Sbjct: 886 SRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRK-----EESDKNYFEG 940
Query: 1055 SGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFG 1114
+GYA V + F ++T D GL+ NG F L + +G L V Y
Sbjct: 941 TGYARV----PTQPHAPIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVRY--- 993
Query: 1115 FSGGPVHLEDTLKKAQ-----INDAKYHEISI-IYHNDKKMILVVDRRHVKSMDNEKMKI 1168
L L K + IN+ + H I I I K+M + VD ++ +D E
Sbjct: 994 ------KLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNT-IIDGE--VF 1044
Query: 1169 PFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYGCP 1228
F+ Y+GG P I + + FRGCMK KK ++ +T+GV C
Sbjct: 1045 DFSTYYLGGIPIAIRERFNISTPA-----FRGCMKNL---KKTSGVVRLNDTVGVTKKCS 1096
Query: 1229 EDSLISRRAYFN-GQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDVFSISLD 1287
ED + R A F+ G + + D + F F+T QP+G+L + + + ++L+
Sbjct: 1097 EDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTLE 1156
Query: 1288 NGTVIMDV--KGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQ 1345
+G + + G + + Y DGL H+V + L++D + + +++
Sbjct: 1157 DGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSK----RLKH 1212
Query: 1346 TQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIE 1405
+S + GGS NF GCISN + R+ EV D + K SL C +
Sbjct: 1213 ISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLN 1265
Query: 1406 SSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSPRA 1465
P +L K +K K + + +D P P ++K+ + C +A
Sbjct: 1266 KPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKVWQ------DACSPLPKTQA 1317
Query: 1466 IEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLA 1525
A Q+G S F+ + +SQF++ ++T SS G++F+ +N FM L+L+
Sbjct: 1318 NHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTG--TKNSFMALYLS 1375
Query: 1526 HGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEAT 1585
GRLV+ KKL+I+S+EK NDG WH V+F + GRLV+DGLR E SL P +T
Sbjct: 1376 KGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSL-PGNST 1434
Query: 1586 WKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPM 1645
I+ P+YLG GK K++ N SF GCL N QL+ + + S +F V+ C GP+
Sbjct: 1435 ISIRAPVYLGSPPSGKP-KSLPTN---SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPL 1490
Query: 1646 ETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQV 1705
E G YFS EGG+VVL S +G +F++ F +RPRS +G L+H S G++L V+++ G+V
Sbjct: 1491 EKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKV 1550
Query: 1706 IVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDH 1765
+++G STSVTPKQSLCDG+WH + V +++ L++D++ ++ G + P
Sbjct: 1551 TASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPAST 1610
Query: 1766 REPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSCP 1821
+EP+ +GG P +L T R+ K F GC+R+ ++ PV ++A V G VS+N CP
Sbjct: 1611 QEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCP 1666
>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
Length = 1724
Score = 756 bits (1953), Expect = 0.0
Identities = 539/1803 (29%), Positives = 873/1803 (48%), Gaps = 122/1803 (6%)
Query: 60 LPPAAEK--CNAGF---FHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCL 114
+PPA + C+ G+ F G+C+ L G + C
Sbjct: 1 MPPAVRRSACSMGWLWIFGAALGQCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCS 60
Query: 115 DGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGY 173
GY D C PC C + C ++G+ C+ C N AG +CERC GY
Sbjct: 61 PGYYRDHKGLYTGRCVPCNCN-----GHSNQC--QDGSGICVNCQHNTAGEHCERCQEGY 113
Query: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCR-NCLRNTTGFKCERCAPGYYGDA 232
YGN + +C+ C C N C G R +C TG +CERCAPGY+G+
Sbjct: 114 YGNA--VHGSCRACPCPHT---NSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 168
Query: 233 -RIAKNCAVCNCGG----GPCDSVTGECL-EEGFEPPTGMDCPTISCDKCVWDLTDALRL 286
+ +C C+C G C +TG+C+ +E + +C CD CV L + L
Sbjct: 169 QKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECD--DCDSCVMTLLNDLAT 226
Query: 287 AALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTM 346
+ KS + +S+ A + + L+ +L + + +I E +
Sbjct: 227 MGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLEREL 286
Query: 347 KSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYY- 405
L + E L EK SRK Q + N+ ++ + A ++ KI+ + +
Sbjct: 287 TDLNQEFETLQEKAQVNSRKAQTLN-------NNVNRATQSAKELDVKIKNVIRNVHILL 339
Query: 406 -------GEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEAD--EAYELLSQ 456
GE + + + S + AQ+M+ E+R+R + L + EAD E+ LL++
Sbjct: 340 KQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRN---FGKHLREAEADKRESQLLLNR 396
Query: 457 AESWQRLHN-ETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRD 515
+WQ+ H E L + + L++Y AKLSDL+ L +A + A +N+
Sbjct: 397 IRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGA 456
Query: 516 HEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVK 575
++Q + + L+T+ SL + L ++ K + A ++ A+ EL K
Sbjct: 457 IQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDK 516
Query: 576 LSNLSNLSH--DLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNY 633
+ LS + LV+EA HA+ LQ+ A +L ++ + LV+ A+DA+ YENI+N
Sbjct: 517 VRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNA 576
Query: 634 VSEANETAEFALNTTDRIYDAV--SGIDTQIIYHKDESENLLNQARELQAKAESSSDEAV 691
+ A + A A + ++ V + + S+ LLN+A+ Q K + A+
Sbjct: 577 IKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPAL 636
Query: 692 ADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQA 751
+ + + +K + T L+ L +RGD + ++ + +AN T EV
Sbjct: 637 NNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDG 696
Query: 752 TAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKR-PASN 810
P+ ++ + + A+ A ++V LT +P L ++ ++ Q+ P N
Sbjct: 697 LNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGN 756
Query: 811 VSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVK 870
+S ++ RIRELI Q R ASK+ V M F+G+S VEV ++DLK +TSLSL+++ P
Sbjct: 757 ISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNS 816
Query: 871 RPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWP-- 928
R E T + F++YLG+K+A ++Y+G+A+ + L VYNLG ++ E+ +D S
Sbjct: 817 R-ENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKE 875
Query: 929 AYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVP 988
A VK +R+ + ++ T + SS E + + ++LL+LDPE+ VFYVGG P
Sbjct: 876 AVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYP 935
Query: 989 SNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAA 1048
+FKLP+ L+ P + GC+EL LN +V+SLYNFK +N++ + PC R K +
Sbjct: 936 PDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRK-----EESD 990
Query: 1049 SYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLH 1108
+F+G+GYA V + F ++T D GL+ NG F L + +G L
Sbjct: 991 KNYFEGTGYARVPTQPH----APIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLM 1046
Query: 1109 VFYDFGFSGGPVHLEDTLKKAQ-----INDAKYHEISI-IYHNDKKMILVVDRRHVKSMD 1162
V Y L L K + IN+ + H I I I K+M + VD ++ +D
Sbjct: 1047 VRYK---------LNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNT-IID 1096
Query: 1163 NEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLG 1222
E F+ Y+GG P I + + FRGCMK KK ++ +T+G
Sbjct: 1097 GEVFD--FSTYYLGGIPIAIRERFNISTPA-----FRGCMKNL---KKTSGVVRLNDTVG 1146
Query: 1223 VGYGCPEDSLISRRAYFN--GQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSD 1280
V C ED + R A F+ GQ + + D + F F+T QP+G+L + + +
Sbjct: 1147 VTKKCSEDWKLVRSASFSRGGQLSFTDLG-LPPTDHLQASFGFQTFQPSGILLDHQTWTR 1205
Query: 1281 VFSISLDNGTVIMDVK--GIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSKNP 1338
++L++G + + G + + Y DGL H+V + L++D + +
Sbjct: 1206 NLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSK- 1264
Query: 1339 TKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTS 1398
+++ +S + GGS NF GCISN + R+ EV D + K S
Sbjct: 1265 ---RLKHISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVS 1314
Query: 1399 LYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCH 1458
L C + P +L K +K K + + +D P P ++K+ + C
Sbjct: 1315 LGGCSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKVWQ------DACS 1366
Query: 1459 LSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEEND 1518
+A A Q+G S F+ + +SQF++ ++T SS G++F+ + N
Sbjct: 1367 PLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTK--NS 1424
Query: 1519 FMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEES 1578
FM L+L+ GRLV+ KKL+I+S+EK NDG WH V+F + GRLV+DGLR E S
Sbjct: 1425 FMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGS 1484
Query: 1579 LPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVT 1638
LP +T I+ P+YLG GK K++ NS F GCL N QL+ + + S +F V+
Sbjct: 1485 LPGN-STISIRAPVYLGSPPSGKP-KSLPTNS---FVGCLKNFQLDSKPLYTPSSSFGVS 1539
Query: 1639 PCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNV 1698
C GP+E G YFS EGG+VVL S +G +F++ F +RPRS +G L+H S G++L V
Sbjct: 1540 SCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCV 1599
Query: 1699 HMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPL 1758
+++ G+V +++G STSVTPKQSLCDG+WH + V +++ L++D++ ++ G +
Sbjct: 1600 YLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQI 1659
Query: 1759 NPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSIN 1818
P +EP+ +GG P +L T R+ K F GC+R+ ++ PV ++A V G VS+N
Sbjct: 1660 PFPPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLN 1719
Query: 1819 SCP 1821
CP
Sbjct: 1720 GCP 1722
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 690 bits (1781), Expect = 0.0
Identities = 536/1929 (27%), Positives = 883/1929 (45%), Gaps = 242/1929 (12%)
Query: 63 AAEKCNAGFFHTLSG----ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYI 118
+ ++C GF+ + G CVPC C+G+S+ CL GSG CV CQ NT G HCE+C G++
Sbjct: 1841 SCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFV 1900
Query: 119 GDSIRGAPQF-CQPCPCPLPHLAN-FAESCYRKNGAVR---------------------- 154
S R P C CPCPL +N FAE C + G +
Sbjct: 1901 --SSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGN 1958
Query: 155 ----------CICNEN-----------------------YAGPNCERCAPGYYGNPLLIG 181
C C+ N GP CE CAPG+YGN LL G
Sbjct: 1959 PLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPG 2018
Query: 182 STCKKCDC-----------SGNS--------------------------------DPNLI 198
+ C +CDC SG+ P
Sbjct: 2019 N-CTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAE 2077
Query: 199 FEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEE 258
+C +GQC +C T G +C CAPGY+G + C C C GG CD TG C
Sbjct: 2078 GSECHPQSGQC-HCRPGTMGPQCRECAPGYWGLPE--QGCRRCQCPGGRCDPHTGRCNC- 2133
Query: 259 GFEPP--TGMDCPTIS--------------------CDKCVWDLTDALRLAALSIEEGKS 296
PP +G C T S CD CV L D L A +
Sbjct: 2134 ---PPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHCVVLLLDDLERAGALLPAIHE 2190
Query: 297 GVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEEL 356
+ +++ + A ++ +NA+I L+++L Q+ E SL D L
Sbjct: 2191 QLRGINASSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQDARRL 2250
Query: 357 ----VEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELS 412
V +QAS+ L E+ T+ HA L+ + + E+ ++ + G + +
Sbjct: 2251 GGQAVGTRDQASQL--LAGTEA--TLGHAKTLLAAIRAVDRTLSELMSQTGHLGLANASA 2306
Query: 413 P--KEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQA-ESWQRLHNETRT 469
P +++ L +++L E+R+R + + E A LL++ E L E +
Sbjct: 2307 PSGEQLLRTLAEVERLLWEMRARD-LGAPQAAAEAELAAAQRLLARVQEQLSSLWEENQA 2365
Query: 470 LFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEV 529
L ++L + A L DL+EAL++A++ R+A+++N R + ++++ +
Sbjct: 2366 LATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEALQRKQELSRDNAT 2425
Query: 530 VNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDL--V 587
+ +L + D+L + L LD + + A +DGA++ L ++ S L V
Sbjct: 2426 LQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFSPAGSKLRLV 2485
Query: 588 QEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNT 647
+ A HAQ L Q A LS + + + L Q+A++ASN Y I+ V A + A AL
Sbjct: 2486 EAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQALQQ 2545
Query: 648 TDRIYDAVSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSA 707
D + V + L+++A++L A + ++ +EA+ +R+G A
Sbjct: 2546 ADHTWATVV------------RQGLVDRAQQLLANS-TALEEAMLQEQQRLGLVWAALQG 2592
Query: 708 LKTRLSD-------------AVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAP 754
+T+L D A + + A + + +++ ++ + EA T VQ
Sbjct: 2593 ARTQLRDVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAAEAQDTATRVQSQLQA 2652
Query: 755 MANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQK---RPASNV 811
M N+ W + AV A +V L + +PQLL +L +E + + +
Sbjct: 2653 MQENVERWQGQYEGLRGQDLGQAVLDAGHSVSTLEKTLPQLLAKLSILENRGVHNASLAL 2712
Query: 812 SASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKR 871
SASI R+RELIAQ R ASK++V M F+G+S V++ + + DL A+T+L Y++ P
Sbjct: 2713 SASIGRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYTALKFYLQGPEPE 2772
Query: 872 PELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYF 931
P T D+F++Y+GS+ A +YMG+++++ + +VY LG + + + F
Sbjct: 2773 PG-QGTEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQLGEAGPAVLSIDEDIGE---QF 2828
Query: 932 SIVKIERVGKHGKVFLTVPSLSSTAEEKFIK--KGEF--SGDDSLLDLDPEDTVFYVGGV 987
+ V ++R + G + +TV E + I+ KG+ G + LL+L P+D VFYVGG
Sbjct: 2829 AAVSLDRTLQFGHMSVTV-------ERQMIQETKGDTVAPGAEGLLNLRPDDFVFYVGGY 2881
Query: 988 PSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRA 1047
PS F P L PG+ GC+E+ TLN +V+SLYNF+ + +D + PCAR K
Sbjct: 2882 PSTFTPPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDPWLT 2941
Query: 1048 ASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYL 1107
+ DG+G+A I+ + RF+ E+R + +G++ + S F L ++ G L
Sbjct: 2942 DGSYLDGTGFA---RISFDSQISTTKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQEGSL 2998
Query: 1108 HVFYDFGF---SGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNE 1164
+ YDFG P+ L A +K ++ ++ + K++++ V+R V S++ +
Sbjct: 2999 VLLYDFGAGLKKAVPLQPPPPLTSA----SKAIQVFLLGGSRKRVLVRVERATVYSVEQD 3054
Query: 1165 KMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVG 1224
Y+GG PP+ L +LR P + RGC+KG + K + L++ T GV
Sbjct: 3055 NDLELADAYYLGGVPPDQLPP-SLRRLFPTGGSVRGCVKGIKALGKYVD-LKRLNTTGVS 3112
Query: 1225 YGCPEDSLISRRAYFNGQSFI-ASIQKISFFDG-FEGGFNFRTLQPNGLLFYYASGSDVF 1282
GC D L+ R F+G F+ ++ ++ G GF F + Q + LL+Y AS +
Sbjct: 3113 AGCTADLLVGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYYRASPDGLC 3172
Query: 1283 SISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGK 1342
+SL G V + + +V++ + DG H+V + T L VD ++ P +G
Sbjct: 3173 QVSLQQGRVSLQLLRTEVKT-QAGFADGAPHYVAFYSNATGVWLYVD-DQLQQMKPHRGP 3230
Query: 1343 IEQTQASEK---KFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSL 1399
+ Q + + GG P S NF+GCISN + R+ V D Q+ V+ S
Sbjct: 3231 PPELQPQPEGPPRLLLGGLPESGTIYNFSGCISNVFVQRLLGPQRVFDLQQNLGSVNVST 3290
Query: 1400 YECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHL 1459
P + L +G + KAS+ + P+ P + P T R+S
Sbjct: 3291 GCAPALQAQTPGLGPRGLQATARKASRRSR------QPARHPACMLPPHLRTTRDS---- 3340
Query: 1460 SNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSD-QEEND 1518
YQ+GG+ +S EF + S+ + RSS G++ + + + +
Sbjct: 3341 ----------YQFGGSLSSHLEFVGILARHRNWPSLSMHVLPRSSRGLLLFTARLRPGSP 3390
Query: 1519 FMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEES 1578
+ LFL++G V +L+ +S+++ G WH V E++ LV DG R +
Sbjct: 3391 SLALFLSNGHFVAQMEGLGTRLRAQSRQRSRPGRWHKVSVRWEKNRILLVTDGARAWSQE 3450
Query: 1579 LPPTE---ATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTF 1635
P + A +++GG+ + + FSGC+ L+L+G + + ++
Sbjct: 3451 GPHRQHQGAEHPQPHTLFVGGLPASSHSSKLPVT--VGFSGCVKRLRLHGRPLGAPTRMA 3508
Query: 1636 SVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH-GHSVNGE 1694
VTPC GP+E G +F GG + LD + EVRP + +G + H G +
Sbjct: 3509 GVTPCILGPLEAGLFFPGSGGVITLDLPGATLPDVGLELEVRPLAVTGLIFHLGQARTPP 3568
Query: 1695 YLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHV 1754
YL + + QV+++ ++G +FSTSVT LCDG+WHR+ V++ NV++L+VD++ NH
Sbjct: 3569 YLQLQVTEKQVLLRADDGAGEFSTSVTRPSVLCDGQWHRLAVMKSGNVLRLEVDAQSNHT 3628
Query: 1755 VGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGA 1814
VGPL P+++GG+PE + P+ + GC+R ++ PV+ +++ V GA
Sbjct: 3629 VGPLLAAAAGAPAPLYLGGLPEPMAVQPWPPA--YCGCMRRLAVNRSPVAMTRSVEVHGA 3686
Query: 1815 VSINSCPAA 1823
V + CPAA
Sbjct: 3687 VGASGCPAA 3695
Score = 100 bits (249), Expect = 1e-20
Identities = 71/238 (29%), Positives = 98/238 (41%), Gaps = 53/238 (22%)
Query: 76 SGECVPCDCNGNSNEC--------------LDGS----GYCVHCQRNTTGEHCEKCLDGY 117
+ EC C+C G++ +C LDG+ G C+ CQ +TTG +CE+CL G+
Sbjct: 353 ANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGF 412
Query: 118 IGDSIR--GAPQFCQPCPCPLPHLANFAE-SCYRKNGAVRCICNENYAGPNCERCAPGYY 174
+P C+ C C ++F + +C G RC C N++G C+ CA G+
Sbjct: 413 YRSPNHPLDSPHVCRRCNCE----SDFTDGTCEDLTG--RCYCRPNFSGERCDVCAEGFT 466
Query: 175 GNP---------------LLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGF 219
G P +L CDCS D G+C C N G
Sbjct: 467 GFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRK-DPRVGRCL-CKPNFQGT 524
Query: 220 KCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGEC-LEEGFEPPTGMDCPTISCDKC 276
CE CAPG+YG C+ CD TG+C GFE T CD+C
Sbjct: 525 HCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGAT--------CDRC 574
Score = 99.8 bits (247), Expect = 2e-20
Identities = 74/245 (30%), Positives = 100/245 (40%), Gaps = 46/245 (18%)
Query: 40 SAVGRQDPPETSEPRVALGRLPPA-----AEKCNAGFFHTLSGECVPCDCNGNS---NEC 91
SA G Q +PRV P E C GF+ C PC C+ + C
Sbjct: 497 SAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFY---GPGCQPCQCSSPGVADDRC 553
Query: 92 LDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNG 151
+G C C+ G C++C GY + CQ C C E C +
Sbjct: 554 DPDTGQC-RCRVGFEGATCDRCAPGYFHFPL------CQLCGCS--PAGTLPEGC---DE 601
Query: 152 AVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRN 211
A RC+C +AGP+C+RC PGY+G P C+ C C DP + G CR
Sbjct: 602 AGRCLCQPEFAGPHCDRCRPGYHGFP-----NCQACTC----DPRGALDQLCGAGGLCR- 651
Query: 212 CLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGECLEEGFEP-PTG 265
C TG C+ C+PG++G +C C+C CD +G+C P TG
Sbjct: 652 CRPGYTGTACQECSPGFHG----FPSCVPCHCSAEGSLHAACDPRSGQC---SCRPRVTG 704
Query: 266 MDCPT 270
+ C T
Sbjct: 705 LRCDT 709
Score = 98.6 bits (244), Expect = 5e-20
Identities = 66/205 (32%), Positives = 90/205 (43%), Gaps = 40/205 (19%)
Query: 81 PCDCN---GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
PC C+ C G C C + G C +C GY G P C+PC C
Sbjct: 1437 PCGCHEVGATGPTCEPFGGQCP-CHAHVIGRDCSRCATGYWG-----FPN-CRPCDCG-- 1487
Query: 138 HLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNL 197
A C G +CIC P+C C P +G L+G C++C+CSG L
Sbjct: 1488 -----ARLCDELTG--QCICPPRTIPPDCLLCQPQTFGCHPLVG--CEECNCSGPGIQEL 1538
Query: 198 IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC-----GGGPCDSVT 252
CD +GQC+ C N TG +C+ C+PG++G R C C+C G CD +T
Sbjct: 1539 TDPTCDTDSGQCK-CRPNVTGRRCDTCSPGFHGYPR----CRPCDCHEAGTAPGVCDPLT 1593
Query: 253 GEC-LEEGFEPPTGMDCPTISCDKC 276
G+C +E + P CD+C
Sbjct: 1594 GQCYCKENVQGP--------KCDQC 1610
Score = 83.2 bits (204), Expect = 2e-15
Identities = 59/202 (29%), Positives = 82/202 (40%), Gaps = 22/202 (10%)
Query: 63 AAEKCNAGFFHTLSGECVPCDCNGNSN---ECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
A ++C+ GF S CVPC C+ + C SG C C+ TG C+ C+ G
Sbjct: 660 ACQECSPGFHGFPS--CVPCHCSAEGSLHAACDPRSGQC-SCRPRVTGLRCDTCVPGAYN 716
Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
+C+ C LA + V C+C + GP+C+RC PG++G
Sbjct: 717 FP------YCEAGSCHPAGLAPVDPAL--PEAQVPCMCRAHVEGPSCDRCKPGFWGLSPS 768
Query: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNC 238
C +C C + E C TGQC C + G C C G++G D C
Sbjct: 769 NPEGCTRCSCDLRGTLGGVAE-CQPGTGQC-FCKPHVCGQACASCKDGFFGLDQADYFGC 826
Query: 239 AVCNCG-----GGPCDSVTGEC 255
C C G C+ TG C
Sbjct: 827 RSCRCDIGGALGQSCEPRTGVC 848
Score = 83.2 bits (204), Expect = 2e-15
Identities = 55/171 (32%), Positives = 77/171 (45%), Gaps = 23/171 (13%)
Query: 79 CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG-DSIRGAPQFCQPCPCPLP 137
C PCDC C + +G C+ C T C C G + G C+ C C P
Sbjct: 1481 CRPCDCGARL--CDELTGQCI-CPPRTIPPDCLLCQPQTFGCHPLVG----CEECNCSGP 1533
Query: 138 HLANFAE-SCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDC-SGNSDP 195
+ + +C +G +C C N G C+ C+PG++G P C+ CDC + P
Sbjct: 1534 GIQELTDPTCDTDSG--QCKCRPNVTGRRCDTCSPGFHGYP-----RCRPCDCHEAGTAP 1586
Query: 196 NLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCGG 245
+ CD +TGQC C N G KC++C+ G + DA K C C C G
Sbjct: 1587 GV----CDPLTGQCY-CKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFG 1632
Score = 75.9 bits (185), Expect = 3e-13
Identities = 53/188 (28%), Positives = 80/188 (42%), Gaps = 46/188 (24%)
Query: 74 TLSGECVPCDCNGNSNEC-----LDGSGYCVHCQRNTTGEHCEKCLDGYIGD----SIRG 124
++ G CV C+G+++ C D CQ NT G C++C G+ +
Sbjct: 295 SIGGRCV---CHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATAN 351
Query: 125 APQFCQPCPCPLPHLANFAESCY-----------------RKNGAVRCICNENYAGPNCE 167
+ CQ C C A CY + G V C + G NCE
Sbjct: 352 SANECQSCNC-----YGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCE 406
Query: 168 RCAPGYY---GNPLLIGSTCKKCDCSGNSDPNLIFED--CDEVTGQCRNCLRNTTGFKCE 222
RC PG+Y +PL C++C+C + F D C+++TG+C C N +G +C+
Sbjct: 407 RCLPGFYRSPNHPLDSPHVCRRCNCESD------FTDGTCEDLTGRC-YCRPNFSGERCD 459
Query: 223 RCAPGYYG 230
CA G+ G
Sbjct: 460 VCAEGFTG 467
Score = 68.9 bits (167), Expect = 4e-11
Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 29/142 (20%)
Query: 143 AESCYRKNGA----VRCICNENYAGPNCERCAPGYYGNP-----LLIGSTCKKCDCSGNS 193
A++C K+ ++C C N G C+RC PG+ P + C+ C+C G++
Sbjct: 306 ADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHA 365
Query: 194 -----DPNL-------IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN---- 237
DP + + + G C +C +TTG CERC PG+Y +
Sbjct: 366 TDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHV 425
Query: 238 CAVCNCGG----GPCDSVTGEC 255
C CNC G C+ +TG C
Sbjct: 426 CRRCNCESDFTDGTCEDLTGRC 447
Score = 65.9 bits (159), Expect = 4e-10
Identities = 46/144 (31%), Positives = 63/144 (43%), Gaps = 22/144 (15%)
Query: 60 LPPAAEKCNAGFF--HTLSGECVPCDCNGNSNE------CLDGSGYCVHCQRNTTGEHCE 111
+PP C F H L G C C+C+G + C SG C C+ N TG C+
Sbjct: 1505 IPPDCLLCQPQTFGCHPLVG-CEECNCSGPGIQELTDPTCDTDSGQC-KCRPNVTGRRCD 1562
Query: 112 KCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAES-CYRKNGAVRCICNENYAGPNCERCA 170
C G+ G P+ C+PC C H A A C G +C C EN GP C++C+
Sbjct: 1563 TCSPGF-----HGYPR-CRPCDC---HEAGTAPGVCDPLTG--QCYCKENVQGPKCDQCS 1611
Query: 171 PGYYGNPLLIGSTCKKCDCSGNSD 194
G + C +C C G ++
Sbjct: 1612 LGTFSLDAANPKGCTRCFCFGATE 1635
Score = 62.8 bits (151), Expect = 3e-09
Identities = 33/92 (35%), Positives = 45/92 (48%), Gaps = 10/92 (10%)
Query: 155 CICNENYAGPNCERCAPGYYGN--PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNC 212
C+C +Y G +C+ CAPG+Y + L +G C C C G+SD C +G C +C
Sbjct: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLG-RCVPCQCHGHSD------RCLPGSGVCVDC 1883
Query: 213 LRNTTGFKCERCAPGYYGDA-RIAKNCAVCNC 243
NT G CERC G+ + C C C
Sbjct: 1884 QHNTEGAHCERCQAGFVSSRDDPSAPCVSCPC 1915
Score = 59.3 bits (142), Expect = 3e-08
Identities = 48/169 (28%), Positives = 69/169 (40%), Gaps = 23/169 (13%)
Query: 21 CSRAASGDDNAFPFDIEGS---SAVGRQDP--PETSEPRVALGRLP-PAAEKCNAGFFHT 74
C G N FP+ GS + + DP PE P + + P+ ++C GF+
Sbjct: 707 CDTCVPGAYN-FPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGL 765
Query: 75 LSGE---CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
C C C+ G EC G+G C C+ + G+ C C DG+ G + A
Sbjct: 766 SPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCF-CKPHVCGQACASCKDGFFG--LDQAD 822
Query: 127 QF-CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
F C+ C C + +SC + G C C N GP C A +Y
Sbjct: 823 YFGCRSCRCDIG--GALGQSCEPRTGV--CRCRPNTQGPTCSEPARDHY 867
Score = 54.7 bits (130), Expect = 8e-07
Identities = 37/122 (30%), Positives = 53/122 (43%), Gaps = 27/122 (22%)
Query: 178 LLIGSTCKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
L + + C C G + P C+ GQC C + G C RCA GY+G
Sbjct: 1429 LFYNNGARPCGCHEVGATGPT-----CEPFGGQCP-CHAHVIGRDCSRCATGYWG----F 1478
Query: 236 KNCAVCNCGGGPCDSVTGECL-EEGFEPPTGMDC--------PTISCDKC------VWDL 280
NC C+CG CD +TG+C+ PP + C P + C++C + +L
Sbjct: 1479 PNCRPCDCGARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQEL 1538
Query: 281 TD 282
TD
Sbjct: 1539 TD 1540
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 418 bits (1075), Expect = e-116
Identities = 450/1865 (24%), Positives = 778/1865 (41%), Gaps = 226/1865 (12%)
Query: 57 LGRLPPAAEKCNAGFFHTLS-----------GECVPCDCNGNSNECLDGSGYCVHCQRNT 105
LG + E C GF+ S G CVPC CNG+S+ C + C +CQ +T
Sbjct: 1384 LGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHT 1443
Query: 106 TGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLA-NFAESCYRKN-GAVRC-ICNENYA 162
G+ CE+C GY G ++G P CQ C CPL + NF+ SC + RC C Y
Sbjct: 1444 AGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYE 1502
Query: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDP-NLIFEDCDEVTGQCRNCLRNTTGFKC 221
G CERCAPGY G+P G +C++C+C DP + CD VTG C C TG KC
Sbjct: 1503 GQYCERCAPGYTGSPGNPGGSCQECEC----DPYGSLPVPCDPVTGFC-TCRPGATGRKC 1557
Query: 222 ERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLT 281
+ C + AR C C G C + L
Sbjct: 1558 DGCK---HWHAREGWECVFC---GDECTGLL---------------------------LG 1584
Query: 282 DALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINN 341
D RL + + +G L A ++ + + LK LS + L I
Sbjct: 1585 DLARLEQMVMSINLTGPL-----PAPYKMLYGLENMTQELKHLLSPQRAPERL----IQL 1635
Query: 342 AENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNK 401
AE + +L++++ EL+ + + + G+ +++ T A L E ++ + +N K
Sbjct: 1636 AEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEK 1695
Query: 402 MLYYGEEHELSPKEISEKLVLAQK----MLEEIRSRQPFFTQRELVDEEADEAYELLSQA 457
+ E + L QK M++E+R R+ TQ+E+ ++E A LL +
Sbjct: 1696 AIKLNETLGTRDEAFERNLEGLQKEIDQMIKELR-RKNLETQKEIAEDELVAAEALLKKV 1754
Query: 458 ES-WQRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDH 516
+ + E + + E+L DY K+ D + L +A + +R+A NR A Q++
Sbjct: 1755 KKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREA---NRLFAVNQKNM 1811
Query: 517 ---EKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQ 573
EK++E V + +L D L E++ II I ++ EL
Sbjct: 1812 TALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELN 1871
Query: 574 VKLSNLSNLSHD-LVQEAIDHAQDLQQEANELSRKLHS--SDMNGLVQKALDASNVYENI 630
K+ +LS D + E + A+ + N+ S L + + A A Y NI
Sbjct: 1872 DKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFKAYSNI 1931
Query: 631 VNYVSEANETAEFALNTTDRIYDAVSG----IDTQIIYHKDESENLLNQARELQAKAESS 686
+Y+ EA + A+ A + +G + +S +LN+A++L + +
Sbjct: 1932 KDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVKEN 1991
Query: 687 SDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTM 746
D + R+ A AR L L+D + +L A D +L + +AN T
Sbjct: 1992 EDH-LNGLKTRIENADARNGDLLRTLNDTLGKLSAIP-NDTAAKLQAVKDKARQANDTAK 2049
Query: 747 EVQQATAPMANNLTNWSQNLQHFDSS-----------AYNTAVNSARDAVRNLTEVVPQL 795
+V + NL +N S + N + A V+NL + +L
Sbjct: 2050 DVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRL 2109
Query: 796 LDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDL 855
+D+L+ + K N+ +I I+ELI Q R A+ I+VS+ G RT ++
Sbjct: 2110 IDKLKPI--KELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCI-----RTYKPEI 2162
Query: 856 K--AFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTK 913
K ++ ++ + +K T AD + YLGS +++ + ++ + +++++G+
Sbjct: 2163 KKGSYNNIVVNVK--------TAVADNLLFYLGSAKF-IDFLAIEMRKGKVSFLWDVGSG 2213
Query: 914 DVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLL 973
+ + +Y+ + R G++G + + + ++L
Sbjct: 2214 VGRVEYPDLTIDD--SYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTIL 2271
Query: 974 DLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIY-NMDPSTS 1032
D+D + + +VGG+ K ++ + F GC+ +N I L+NF+ + T
Sbjct: 2272 DVD-ANAMLFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTV 2330
Query: 1033 VPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMV 1092
P D Q FDG GYA+V R + ++ + RT + + L++ +
Sbjct: 2331 SPQVEDSEGTIQ-------FDGEGYALVSRPIR--WYPNISTVMFKFRTFSSSALLMYLA 2381
Query: 1093 NGSM--FFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMI 1150
+ F +E+ +G++ V YD G SG + + ND K+ ++ + I
Sbjct: 2382 TRDLRDFMSVELTDGHIKVSYDLG-SG----MASVVSNQNHNDGKWKSFTLSRIQKQANI 2436
Query: 1151 LVVD-----RRHV---KSMDNEKMKIPFTD-IYIGGAPPEILQSRALRAHLPLDI-NFRG 1200
+VD ++ S +N + + D IY GG P L++ +++A +++ + G
Sbjct: 2437 SIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLP--TLRNLSMKARPEVNLKKYSG 2494
Query: 1201 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG 1260
C+K + + +N+L + +GV GC +++ + F F+ + + G E
Sbjct: 2495 CLKDIEISRTPYNILSSPDYVGVTKGCSLENVYT--VSFPKPGFV-ELSPVPIDVGTEIN 2551
Query: 1261 FNFRTLQPNGLLFYYASGSDV-------------FSISLDNG-------TVIMDVKGIKV 1300
+F T +G++ + G+ + I L+ G T ++ I +
Sbjct: 2552 LSFSTKNESGIILLGSGGTPAPPRRKRRQTGQAYYVILLNRGRLEVHLSTGARTMRKIVI 2611
Query: 1301 QSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPI 1360
+ ++DG H V + + + VD++R +N T +EQ KK + GG+P
Sbjct: 2612 RPEPNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLT---VEQ-PIEVKKLFVGGAPP 2667
Query: 1361 SAQ------YANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHK 1414
Q F GCI N V DF R + + C
Sbjct: 2668 EFQPSPLRNIPPFEGCIWNLVINSVPM-----DFARPVSFKNADIGRC------------ 2710
Query: 1415 KGKNLSKPKASQNKKGGKSKD-APSWDPVALKLPERNTPRNSH--CHLSNSPRAIEHAYQ 1471
+ K +++ G + +PV TP +H C + P + + Q
Sbjct: 2711 -----AHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALLIGSKQ 2765
Query: 1472 YGGTANSRQEFEHLKGDFGAKSQFSIRL--RTRSSHGMIFYVSDQEENDFMTLFLAHGRL 1529
+G + NS D K++ +I L RT + G++FY++ DF T+ L +G
Sbjct: 2766 FGLSRNSHIAIAF--DDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLP 2823
Query: 1530 VYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEA-TWKI 1588
+ +++G K NDG WH + +R + G L +DG ++ P +A +
Sbjct: 2824 YFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDG--ASNRTISPKKADILDV 2881
Query: 1589 KGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQL--NGASITSASQTFSVTPCFEGPME 1646
G +Y+GG+ + + YS GC+ NL + A + + +F V CF +
Sbjct: 2882 VGMLYVGGLPINYTTRRIG-PVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFAN-AQ 2939
Query: 1647 TGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVI 1706
GTYF G+ F +GL + FE R +++G L+ S + + + M + +++
Sbjct: 2940 RGTYFDGT-GFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM 2998
Query: 1707 VKVNNGIRDFST--SVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNP--KP 1762
V+NG F+ LCDG+WH++T + + ++L VD P NP
Sbjct: 2999 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSP-NPASTS 3057
Query: 1763 IDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVI---DGHP--VSFSKAALVSGAVSI 1817
D +PVFVGG P+ L L S PF GCIR + G P V+F+KA + G +
Sbjct: 3058 ADTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPV 3117
Query: 1818 NSCPA 1822
SCPA
Sbjct: 3118 -SCPA 3121
Score = 171 bits (433), Expect = 6e-42
Identities = 84/202 (41%), Positives = 113/202 (55%), Gaps = 12/202 (5%)
Query: 62 PAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
P + N F G C PC C G++ C D +G C++C+ +T G +C+KCL G+ G+
Sbjct: 740 PRHRRVNGTIF---GGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEP 796
Query: 122 IRGAPQFCQPCPCPLPHLA-NFAESCY--RKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
+G + CQPC CPL + NF+ +C+ R G + C Y GP CERCA GY+G P
Sbjct: 797 TKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS 856
Query: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC 238
+ G +C+ C C+ N D + I CD ++G C C TTG CE CA GY+GDA AKNC
Sbjct: 857 VPGGSCQPCQCNDNLDFS-IPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNC 915
Query: 239 AVCNCGGG-----PCDSVTGEC 255
C C G C S TG+C
Sbjct: 916 QPCRCNAGGSFSEVCHSQTGQC 937
Score = 130 bits (328), Expect = 9e-30
Identities = 76/210 (36%), Positives = 103/210 (49%), Gaps = 25/210 (11%)
Query: 57 LGRLPPAAEKCNAGFFHTLS---GECVPCDCNGNSNECLDGS-----GYCVHCQRNTTGE 108
+G P E+C G+F S G C PC CN N + + GS G C+ C+ TTG
Sbjct: 837 VGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGR 896
Query: 109 HCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCER 168
+CE C DGY GD++ + CQPC C +F+E C+ + G +C C N G C++
Sbjct: 897 YCELCADGYFGDAVDA--KNCQPCRCNAG--GSFSEVCHSQTG--QCECRANVQGQRCDK 950
Query: 169 CAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGY 228
C G +G L C C+C+ + DC+E +GQC C TG KC+RCA GY
Sbjct: 951 CKAGTFG--LQSARGCVPCNCNSFGSKSF---DCEE-SGQCW-CQPGVTGKKCDRCAHGY 1003
Query: 229 YGDARIAKNCAVCNCG--GGPCDSVTGECL 256
+ C C C G CD TG C+
Sbjct: 1004 FNFQE--GGCTACECSHLGNNCDPKTGRCI 1031
Score = 112 bits (281), Expect = 3e-24
Identities = 78/222 (35%), Positives = 108/222 (48%), Gaps = 32/222 (14%)
Query: 65 EKCNAGFFHTLSGE-CVPCDCNGNSNECLD--GSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
+KC AG F S CVPC+CN ++ D SG C CQ TG+ C++C GY
Sbjct: 949 DKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQC-WCQPGVTGKKCDRCAHGYFNFQ 1007
Query: 122 IRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIG 181
G C C C HL N +C K G RCIC N G C +CAP +G+ + G
Sbjct: 1008 EGG----CTACECS--HLGN---NCDPKTG--RCICPPNTIGEKCSKCAPNTWGHSITTG 1056
Query: 182 STCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVC 241
CK C+CS + +L F+ C+ TGQC NC +G KC C+ G++ R C +C
Sbjct: 1057 --CKACNCS--TVGSLDFQ-CNVNTGQC-NCHPKFSGAKCTECSRGHWNYPR----CNLC 1106
Query: 242 NC-----GGGPCDSVTGE--CLEEGFEPPTGMDCPTISCDKC 276
+C CDS T + C ++ + ++ I CD+C
Sbjct: 1107 DCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRC 1148
Score = 102 bits (254), Expect = 3e-21
Identities = 63/200 (31%), Positives = 87/200 (43%), Gaps = 26/200 (13%)
Query: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
++C G+F+ G C C+C+ N C +G C+ C NT GE C KC G SI
Sbjct: 997 DRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCI-CPPNTIGEKCSKCAPNTWGHSITT 1055
Query: 125 APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
C+ C C +F C G +C C+ ++G C C+ G++ P C
Sbjct: 1056 G---CKACNCSTVGSLDF--QCNVNTG--QCNCHPKFSGAKCTECSRGHWNYP-----RC 1103
Query: 185 KKCDC------SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKN 237
CDC + D C + TGQC C N G C+RC PG +G DA+
Sbjct: 1104 NLCDCFLPGTDATTCDSETKKCSCSDQTGQC-TCKVNVEGIHCDRCRPGKFGLDAKNPLG 1162
Query: 238 CAVCNCGGGPCDSVTGECLE 257
C+ C C G T +C E
Sbjct: 1163 CSSCYCFG-----TTTQCSE 1177
Score = 97.8 bits (242), Expect = 8e-20
Identities = 64/204 (31%), Positives = 85/204 (41%), Gaps = 40/204 (19%)
Query: 69 AGFFHTLSGECVPCDCNGNSNECLD------------------GSGYCVHCQRNTTGEHC 110
AG F T + EC C+C+G + EC G G C++C +NT G +C
Sbjct: 332 AGTFLTKT-ECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINC 390
Query: 111 EKCLDGYIGDSIRGAPQFCQPC-PCPLPHLANFAESCYRKNGAVR-------CICNENYA 162
E C DG+ +P + +PC PC + + E C + R C C +
Sbjct: 391 ETCTDGFFRPK-GVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFG 449
Query: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCE 222
G +C+RCA GY G P CK C+CSG N D G C C N G C
Sbjct: 450 GVSCDRCARGYTGYP-----DCKACNCSGLGSKNE-----DPCFGPC-ICKENVEGGDCS 498
Query: 223 RCAPGYYG-DARIAKNCAVCNCGG 245
RC G++ K C C C G
Sbjct: 499 RCKSGFFNLQEDNWKGCDECFCSG 522
Score = 77.0 bits (188), Expect = 2e-13
Identities = 53/175 (30%), Positives = 72/175 (41%), Gaps = 42/175 (24%)
Query: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRK----NGAV----------------------R 154
SI A + CQ CP + + ESC+ + NG +
Sbjct: 716 SIAAAVEVCQ---CPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGE 772
Query: 155 CI-CNENYAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDC--DEVTGQ-C 209
C+ C ++ GP C++C PG+YG P C+ C C N N C D G C
Sbjct: 773 CLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLIC 832
Query: 210 RNCLRNTTGFKCERCAPGYYGDARI-AKNCAVCNCGG-------GPCDSVTGECL 256
C TG +CERCA GY+G + +C C C G CDS++G CL
Sbjct: 833 DGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCL 887
Score = 69.7 bits (169), Expect = 2e-11
Identities = 41/153 (26%), Positives = 65/153 (42%), Gaps = 32/153 (20%)
Query: 154 RCICNENYAGPNCERCAPGYYGNP-----LLIGSTCKKCDCSGNSDPNLIFEDCDEVT-- 206
RC C N G +C++C PG++ P L + C+ C+C G ++ E+
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 207 ----------GQCRNCLRNTTGFKCERCAPGYYGDARIAKN----CAVCNCGGGPCDSVT 252
G C NC +NT G CE C G++ ++ N C C+C P S+
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHC--DPIGSLN 423
Query: 253 GECLEEGFEPPTGM-----DCPT----ISCDKC 276
C+++ G+ C T +SCD+C
Sbjct: 424 EVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRC 456
Score = 68.6 bits (166), Expect = 5e-11
Identities = 59/207 (28%), Positives = 78/207 (37%), Gaps = 47/207 (22%)
Query: 82 CDCNGNSNEC-LD---GSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
C C G++ C LD C C+ NT G+ C++C G+ R A F C
Sbjct: 287 CICYGHARACPLDPATNKSRC-ECEHNTCGDSCDQCCPGFHQKPWR-AGTFLTKTECEAC 344
Query: 138 HLANFAESCY------RKN-----------GAVRCICNENYAGPNCERCAPGYY---GNP 177
+ AE CY R+N G V C +N AG NCE C G++ G
Sbjct: 345 NCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVS 404
Query: 178 LLIGSTCKKCDCSGNSDPNLIFEDCDE------VTGQCRNCLRNTTGFKCERCAPGYYGD 231
C+ C C N + ++ G C +C G C+RCA GY G
Sbjct: 405 PNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSC-HCKTGFGGVSCDRCARGYTG- 462
Query: 232 ARIAKNCAVCNCGG----------GPC 248
+C CNC G GPC
Sbjct: 463 ---YPDCKACNCSGLGSKNEDPCFGPC 486
Score = 33.9 bits (76), Expect = 1.5
Identities = 25/70 (35%), Positives = 28/70 (40%), Gaps = 10/70 (14%)
Query: 212 CLRNTTGFKCERCAPGY--YGDARIAKNCAVCNCGGGP--CDSVTGECLEEGFEPPTGMD 267
C TG CE C P + C C C G CD VTGECL + TG
Sbjct: 726 CPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECL--NCKDHTGGP 783
Query: 268 CPTISCDKCV 277
CDKC+
Sbjct: 784 ----YCDKCL 789
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 417 bits (1071), Expect = e-116
Identities = 452/1864 (24%), Positives = 773/1864 (41%), Gaps = 228/1864 (12%)
Query: 57 LGRLPPAAEKCNAGFFHTLS-----------GECVPCDCNGNSNECLDGSGYCVHCQRNT 105
LG + E C GF+ S G CVPC CNG+S+ C + C +CQ +T
Sbjct: 1384 LGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHT 1443
Query: 106 TGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLA-NFAESCYRKN-GAVRC-ICNENYA 162
G+ CE+C GY G ++G P CQ C CPL + NF+ SC + RC C Y
Sbjct: 1444 AGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYE 1502
Query: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDP-NLIFEDCDEVTGQCRNCLRNTTGFKC 221
G CERCAPGY G+P G +C++C+C DP + CD VTG C C TG KC
Sbjct: 1503 GQYCERCAPGYTGSPGNPGGSCQECEC----DPYGSLPVPCDPVTGFC-TCRPGATGRKC 1557
Query: 222 ERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLT 281
+ C + AR C C G C + L
Sbjct: 1558 DGCK---HWHAREGWECVFC---GDECTGLL---------------------------LG 1584
Query: 282 DALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINN 341
D RL + + +G L A ++ + + LK LS + L I
Sbjct: 1585 DLARLEQMVMSINLTGPL-----PAPYKMLYGLENMTQELKHLLSPQRAPERL----IQL 1635
Query: 342 AENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNK 401
AE + +L++++ EL+ + + + G+ +++ T A L E ++ + +N K
Sbjct: 1636 AEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEK 1695
Query: 402 MLYYGEEHELSPKEISEKLVLAQK----MLEEIRSRQPFFTQRELVDEEADEAYELLSQA 457
+ E + L QK M++E+R R+ TQ+E+ ++E A LL +
Sbjct: 1696 AIKLNETLGTRDEAFERNLEGLQKEIDQMIKELR-RKNLETQKEIAEDELVAAEALLKKV 1754
Query: 458 ES-WQRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDH 516
+ + E + + E+L DY K+ D + L +A + +R+A NR A Q++
Sbjct: 1755 KKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREA---NRLFAVNQKNM 1811
Query: 517 ---EKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQ 573
EK++E V + +L D L E++ II I ++ EL
Sbjct: 1812 TALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELN 1871
Query: 574 VKLSNLSNLSHD-LVQEAIDHAQDLQQEANELSRKLHS--SDMNGLVQKALDASNVYENI 630
K+ +LS D + E + A+ + N+ S L + + A A Y NI
Sbjct: 1872 DKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFKAYSNI 1931
Query: 631 VNYVSEANETAEFALNTTDRIYDAVSG----IDTQIIYHKDESENLLNQARELQAKAESS 686
+Y+ EA + A+ A + +G + +S +LN+A++L + +
Sbjct: 1932 KDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVKEN 1991
Query: 687 SDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTM 746
D + R+ A AR L L+D + +L A D +L + +AN T
Sbjct: 1992 EDH-LNGLKTRIENADARNGDLLRTLNDTLGKLSAIP-NDTAAKLQAVKDKARQANDTAK 2049
Query: 747 EVQQATAPMANNLTNWSQNLQHFDSS-----------AYNTAVNSARDAVRNLTEVVPQL 795
+V + NL +N S + N + A V+NL + +L
Sbjct: 2050 DVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRL 2109
Query: 796 LDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDL 855
+D+L+ + K N+ +I I+ELI Q R A+ I+VS+ G RT ++
Sbjct: 2110 IDKLKPI--KELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCI-----RTYKPEI 2162
Query: 856 K--AFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTK 913
K ++ ++ + +K T AD + YLGS +++ + ++ + +++++G+
Sbjct: 2163 KKGSYNNIVVNVK--------TAVADNLLFYLGSAKF-IDFLAIEMRKGKVSFLWDVGSG 2213
Query: 914 DVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLL 973
+ + +Y+ + R G++G + + + ++L
Sbjct: 2214 VGRVEYPDLTIDD--SYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTIL 2271
Query: 974 DLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIY-NMDPSTS 1032
D+D + + +VGG+ K ++ + F GC+ +N I L+NF+ + T
Sbjct: 2272 DVD-ANAMLFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTV 2330
Query: 1033 VPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMV 1092
P D Q FDG GYA+V R + ++ + RT + + L++ +
Sbjct: 2331 SPQVEDSEGTIQ-------FDGEGYALVSRPIR--WYPNISTVMFKFRTFSSSALLMYLA 2381
Query: 1093 NGSM--FFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMI 1150
+ F +E+ +G++ V YD G SG + + ND K+ ++ + I
Sbjct: 2382 TRDLRDFMSVELTDGHIKVSYDLG-SG----MASVVSNQNHNDGKWKSFTLSRIQKQANI 2436
Query: 1151 LVVD-----RRHV---KSMDNEKMKIPFTD-IYIGGAPPEILQSRALRAHLPLDINFRGC 1201
+VD ++ S +N + + D IY GG P R LR + L + GC
Sbjct: 2437 SIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLP----TLRNLRPEVNLK-KYSGC 2491
Query: 1202 MKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGF 1261
+K + + +N+L + +GV GC +++ + F F+ + + G E
Sbjct: 2492 LKDIEISRTPYNILSSPDYVGVTKGCSLENVYT--VSFPKPGFV-ELSPVPIDVGTEINL 2548
Query: 1262 NFRTLQPNGLLFYYASGSDV-------------FSISLDNG-------TVIMDVKGIKVQ 1301
+F T +G++ + G+ + I L+ G T ++ I ++
Sbjct: 2549 SFSTKNESGIILLGSGGTPAPPRRKRRQTGQAYYVILLNRGRLEVHLSTGARTMRKIVIR 2608
Query: 1302 SVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPIS 1361
++DG H V + + + VD++R +N T +EQ KK + GG+P
Sbjct: 2609 PEPNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLT---VEQ-PIEVKKLFVGGAPPE 2664
Query: 1362 AQ------YANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKK 1415
Q F GCI N V DF R + + C
Sbjct: 2665 FQPSPLRNIPPFEGCIWNLVINSVPM-----DFARPVSFKNADIGRC------------- 2706
Query: 1416 GKNLSKPKASQNKKGGKSKD-APSWDPVALKLPERNTPRNSH--CHLSNSPRAIEHAYQY 1472
+ K +++ G + +PV TP +H C + P + + Q+
Sbjct: 2707 ----AHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALLIGSKQF 2762
Query: 1473 GGTANSRQEFEHLKGDFGAKSQFSIRL--RTRSSHGMIFYVSDQEENDFMTLFLAHGRLV 1530
G + NS D K++ +I L RT + G++FY++ DF T+ L +G
Sbjct: 2763 GLSRNSHIAIAF--DDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLPY 2820
Query: 1531 YMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEA-TWKIK 1589
+ +++G K NDG WH + +R + G L +DG ++ P +A +
Sbjct: 2821 FSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDG--ASNRTISPKKADILDVV 2878
Query: 1590 GPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQL--NGASITSASQTFSVTPCFEGPMET 1647
G +Y+GG+ + + YS GC+ NL + A + + +F V CF +
Sbjct: 2879 GMLYVGGLPINYTTRRIG-PVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFAN-AQR 2936
Query: 1648 GTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIV 1707
GTYF G+ F +GL + FE R +++G L+ S + + + M + +++
Sbjct: 2937 GTYFDGT-GFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMF 2995
Query: 1708 KVNNGIRDFST--SVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNP--KPI 1763
V+NG F+ LCDG+WH++T + + ++L VD P NP
Sbjct: 2996 HVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSP-NPASTSA 3054
Query: 1764 DHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVI---DGHP--VSFSKAALVSGAVSIN 1818
D +PVFVGG P+ L L S PF GCIR + G P V+F+KA + G +
Sbjct: 3055 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPV- 3113
Query: 1819 SCPA 1822
SCPA
Sbjct: 3114 SCPA 3117
Score = 171 bits (433), Expect = 6e-42
Identities = 84/202 (41%), Positives = 113/202 (55%), Gaps = 12/202 (5%)
Query: 62 PAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
P + N F G C PC C G++ C D +G C++C+ +T G +C+KCL G+ G+
Sbjct: 740 PRHRRVNGTIF---GGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEP 796
Query: 122 IRGAPQFCQPCPCPLPHLA-NFAESCY--RKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
+G + CQPC CPL + NF+ +C+ R G + C Y GP CERCA GY+G P
Sbjct: 797 TKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS 856
Query: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC 238
+ G +C+ C C+ N D + I CD ++G C C TTG CE CA GY+GDA AKNC
Sbjct: 857 VPGGSCQPCQCNDNLDFS-IPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNC 915
Query: 239 AVCNCGGG-----PCDSVTGEC 255
C C G C S TG+C
Sbjct: 916 QPCRCNAGGSFSEVCHSQTGQC 937
Score = 130 bits (328), Expect = 9e-30
Identities = 76/210 (36%), Positives = 103/210 (49%), Gaps = 25/210 (11%)
Query: 57 LGRLPPAAEKCNAGFFHTLS---GECVPCDCNGNSNECLDGS-----GYCVHCQRNTTGE 108
+G P E+C G+F S G C PC CN N + + GS G C+ C+ TTG
Sbjct: 837 VGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGR 896
Query: 109 HCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCER 168
+CE C DGY GD++ + CQPC C +F+E C+ + G +C C N G C++
Sbjct: 897 YCELCADGYFGDAVDA--KNCQPCRCNAG--GSFSEVCHSQTG--QCECRANVQGQRCDK 950
Query: 169 CAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGY 228
C G +G L C C+C+ + DC+E +GQC C TG KC+RCA GY
Sbjct: 951 CKAGTFG--LQSARGCVPCNCNSFGSKSF---DCEE-SGQCW-CQPGVTGKKCDRCAHGY 1003
Query: 229 YGDARIAKNCAVCNCG--GGPCDSVTGECL 256
+ C C C G CD TG C+
Sbjct: 1004 FNFQE--GGCTACECSHLGNNCDPKTGRCI 1031
Score = 112 bits (281), Expect = 3e-24
Identities = 78/222 (35%), Positives = 108/222 (48%), Gaps = 32/222 (14%)
Query: 65 EKCNAGFFHTLSGE-CVPCDCNGNSNECLD--GSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
+KC AG F S CVPC+CN ++ D SG C CQ TG+ C++C GY
Sbjct: 949 DKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQC-WCQPGVTGKKCDRCAHGYFNFQ 1007
Query: 122 IRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIG 181
G C C C HL N +C K G RCIC N G C +CAP +G+ + G
Sbjct: 1008 EGG----CTACECS--HLGN---NCDPKTG--RCICPPNTIGEKCSKCAPNTWGHSITTG 1056
Query: 182 STCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVC 241
CK C+CS + +L F+ C+ TGQC NC +G KC C+ G++ R C +C
Sbjct: 1057 --CKACNCS--TVGSLDFQ-CNVNTGQC-NCHPKFSGAKCTECSRGHWNYPR----CNLC 1106
Query: 242 NC-----GGGPCDSVTGE--CLEEGFEPPTGMDCPTISCDKC 276
+C CDS T + C ++ + ++ I CD+C
Sbjct: 1107 DCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRC 1148
Score = 102 bits (254), Expect = 3e-21
Identities = 63/200 (31%), Positives = 87/200 (43%), Gaps = 26/200 (13%)
Query: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
++C G+F+ G C C+C+ N C +G C+ C NT GE C KC G SI
Sbjct: 997 DRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCI-CPPNTIGEKCSKCAPNTWGHSITT 1055
Query: 125 APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
C+ C C +F C G +C C+ ++G C C+ G++ P C
Sbjct: 1056 G---CKACNCSTVGSLDF--QCNVNTG--QCNCHPKFSGAKCTECSRGHWNYP-----RC 1103
Query: 185 KKCDC------SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKN 237
CDC + D C + TGQC C N G C+RC PG +G DA+
Sbjct: 1104 NLCDCFLPGTDATTCDSETKKCSCSDQTGQC-TCKVNVEGIHCDRCRPGKFGLDAKNPLG 1162
Query: 238 CAVCNCGGGPCDSVTGECLE 257
C+ C C G T +C E
Sbjct: 1163 CSSCYCFG-----TTTQCSE 1177
Score = 97.8 bits (242), Expect = 8e-20
Identities = 64/204 (31%), Positives = 85/204 (41%), Gaps = 40/204 (19%)
Query: 69 AGFFHTLSGECVPCDCNGNSNECLD------------------GSGYCVHCQRNTTGEHC 110
AG F T + EC C+C+G + EC G G C++C +NT G +C
Sbjct: 332 AGTFLTKT-ECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINC 390
Query: 111 EKCLDGYIGDSIRGAPQFCQPC-PCPLPHLANFAESCYRKNGAVR-------CICNENYA 162
E C DG+ +P + +PC PC + + E C + R C C +
Sbjct: 391 ETCTDGFFRPK-GVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFG 449
Query: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCE 222
G +C+RCA GY G P CK C+CSG N D G C C N G C
Sbjct: 450 GVSCDRCARGYTGYP-----DCKACNCSGLGSKNE-----DPCFGPC-ICKENVEGGDCS 498
Query: 223 RCAPGYYG-DARIAKNCAVCNCGG 245
RC G++ K C C C G
Sbjct: 499 RCKSGFFNLQEDNWKGCDECFCSG 522
Score = 77.0 bits (188), Expect = 2e-13
Identities = 53/175 (30%), Positives = 72/175 (41%), Gaps = 42/175 (24%)
Query: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRK----NGAV----------------------R 154
SI A + CQ CP + + ESC+ + NG +
Sbjct: 716 SIAAAVEVCQ---CPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGE 772
Query: 155 CI-CNENYAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDC--DEVTGQ-C 209
C+ C ++ GP C++C PG+YG P C+ C C N N C D G C
Sbjct: 773 CLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLIC 832
Query: 210 RNCLRNTTGFKCERCAPGYYGDARI-AKNCAVCNCGG-------GPCDSVTGECL 256
C TG +CERCA GY+G + +C C C G CDS++G CL
Sbjct: 833 DGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCL 887
Score = 69.7 bits (169), Expect = 2e-11
Identities = 41/153 (26%), Positives = 65/153 (42%), Gaps = 32/153 (20%)
Query: 154 RCICNENYAGPNCERCAPGYYGNP-----LLIGSTCKKCDCSGNSDPNLIFEDCDEVT-- 206
RC C N G +C++C PG++ P L + C+ C+C G ++ E+
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 207 ----------GQCRNCLRNTTGFKCERCAPGYYGDARIAKN----CAVCNCGGGPCDSVT 252
G C NC +NT G CE C G++ ++ N C C+C P S+
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHC--DPIGSLN 423
Query: 253 GECLEEGFEPPTGM-----DCPT----ISCDKC 276
C+++ G+ C T +SCD+C
Sbjct: 424 EVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRC 456
Score = 68.6 bits (166), Expect = 5e-11
Identities = 59/207 (28%), Positives = 78/207 (37%), Gaps = 47/207 (22%)
Query: 82 CDCNGNSNEC-LD---GSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
C C G++ C LD C C+ NT G+ C++C G+ R A F C
Sbjct: 287 CICYGHARACPLDPATNKSRC-ECEHNTCGDSCDQCCPGFHQKPWR-AGTFLTKTECEAC 344
Query: 138 HLANFAESCY------RKN-----------GAVRCICNENYAGPNCERCAPGYY---GNP 177
+ AE CY R+N G V C +N AG NCE C G++ G
Sbjct: 345 NCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVS 404
Query: 178 LLIGSTCKKCDCSGNSDPNLIFEDCDE------VTGQCRNCLRNTTGFKCERCAPGYYGD 231
C+ C C N + ++ G C +C G C+RCA GY G
Sbjct: 405 PNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSC-HCKTGFGGVSCDRCARGYTG- 462
Query: 232 ARIAKNCAVCNCGG----------GPC 248
+C CNC G GPC
Sbjct: 463 ---YPDCKACNCSGLGSKNEDPCFGPC 486
Score = 33.9 bits (76), Expect = 1.5
Identities = 25/70 (35%), Positives = 28/70 (40%), Gaps = 10/70 (14%)
Query: 212 CLRNTTGFKCERCAPGY--YGDARIAKNCAVCNCGGGP--CDSVTGECLEEGFEPPTGMD 267
C TG CE C P + C C C G CD VTGECL + TG
Sbjct: 726 CPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECL--NCKDHTGGP 783
Query: 268 CPTISCDKCV 277
CDKC+
Sbjct: 784 ----YCDKCL 789
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 391 bits (1004), Expect = e-108
Identities = 426/1837 (23%), Positives = 765/1837 (41%), Gaps = 221/1837 (12%)
Query: 58 GRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117
G+LP +++ L CVPC CN +S+ C +G C++C NT G+HC+ C GY
Sbjct: 1383 GKLPAGSDRGP----RPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGY 1438
Query: 118 IGDSIRGAPQFCQPCPCPLPHLANFAESCYRK-NGAVRC-ICNENYAGPNCERCAPGYYG 175
G + G+ C C CP A+F+ +C + + RC C Y G +CERC+ YYG
Sbjct: 1439 YG-KVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYG 1497
Query: 176 NPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
NP G +C+KCDC+ + + DCD +GQC C +G +C+ C P + +
Sbjct: 1498 NPQTPGGSCQKCDCNPHGS---VHGDCDRTSGQC-VCRLGASGLRCDECEPRH---ILME 1550
Query: 236 KNCAVCNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDALRLAALSIEEGK 295
+C C+ D G L + D + A LS+
Sbjct: 1551 TDCVSCD------DECVGVLLND----------------------LDEIGDAVLSL--NL 1580
Query: 296 SGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEE 355
+G++ V G + N N T YL ++ L E Q L KI++ +L +
Sbjct: 1581 TGIIPVPYGILS----NLENTTKYLQESLLKE-NMQKDLGKIKLEGVAEETDNLQKKLTR 1635
Query: 356 LVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKE 415
++ + +R + + KES D +L ++ +K +N + +E L P
Sbjct: 1636 MLASTQKVNRATERIFKESQDLAIAIERLQMSITEIMEK-TTLNQTL----DEDFLLPNS 1690
Query: 416 ISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQ-AESWQRLHNETRTLFPVV 474
+ + L EI + F + E A +LLSQ E++Q+ E L
Sbjct: 1691 TLQNMQQNGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAA 1750
Query: 475 LEQLDDYNAKLSDLQ------EALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQME 528
L +N +L + EA Q N++ + N + ++ H ++++ + ++
Sbjct: 1751 SHVLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELI 1810
Query: 529 VVNMSLSTSADSLT-TPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLV 587
V L +A + T + L L+D A+I +L + +S + + DLV
Sbjct: 1811 VQGRGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQRNAV--DLV 1868
Query: 588 QEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNT 647
A DHA + Q+ A+ L L ++ + A A+ V+ NI + + E+ E A A T
Sbjct: 1869 YRAEDHAAEFQRLADVLYSGL--ENIRNVSLNATSAAYVHYNIQSLIEESEELARDAHRT 1926
Query: 648 TDRIYDAVSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSA 707
+ + S L + L K + E +++ +
Sbjct: 1927 VTETSLLSESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALE-LSELRNKTNRFQENAVE 1985
Query: 708 LKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQ 767
+ + ++++ L+A +G + + +++ + A+++ + + A ++ L N S +L
Sbjct: 1986 ITRQTNESLLILRAIPKG-IRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLS 2044
Query: 768 HFDSSAYNT---------AVNSARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRI 818
+++ T A A V+++ L D+L+ + K N+S ++ I
Sbjct: 2045 RVNTTLRETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPL--KMLEENLSRNLSEI 2102
Query: 819 RELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETA 878
+ LI+Q R A+ I+V++ D + S + + +L+L +K T+
Sbjct: 2103 KLLISQARKQAASIKVAVSADRDCIRAYQPQISSTN---YNTLTLNVK--------TQEP 2151
Query: 879 DQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPV--SSWPAYFSIVKI 936
D + YLGS A +++ + ++ + ++++LG+ + P+ + W + + +
Sbjct: 2152 DNLLFYLGSSTA-SDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHS----IHV 2206
Query: 937 ERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTS 996
R G G L+V +SS ++ K + G ++LD++ T+ +VGG+ K +
Sbjct: 2207 ARFGNIGS--LSVKEMSSN-QKSPTKTSKSPGTANVLDVN-NSTLMFVGGLGGQIKKSPA 2262
Query: 997 LNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSG 1056
+ + F GCL A LN I L+N+ R +Q+ S+ FDGSG
Sbjct: 2263 VKVTHFKGCLGEAFLNGKSIGLWNYIEREGK--------CRGCFGSSQNEDPSFHFDGSG 2314
Query: 1057 YAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLM--VNGSMFFRLEMRNGYLHVFYDFG 1114
Y+VV + VT+ + T + NGL+L + F +E+ G + V D G
Sbjct: 2315 YSVV----EKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLG 2370
Query: 1115 FSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKIPFTD-- 1172
GP+ L L + N+ +++I+ + + ++ V+D + + + ++ + P
Sbjct: 2371 --SGPITL---LTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSD 2425
Query: 1173 --------IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVG 1224
IY+GG P +SR +R + +F GC+K + + F+LL + GV
Sbjct: 2426 LNRLDKDPIYVGGLP----RSRVVRRGVTTK-SFVGCIKNLEISRSTFDLLR--NSYGVR 2478
Query: 1225 YGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDV--- 1281
GC + + R F +I K S E F T +G++ A G DV
Sbjct: 2479 KGCLLEPI--RSVSFLKGGYIELPPK-SLSPESEWLVTFATTNSSGIIL-AALGGDVEKR 2534
Query: 1282 ----------FSISLDNGTVIMDVK-----GIK---VQSVDKQYNDGLSHFVISSVSPTR 1323
FS+ L G + + V G++ + + +DG +H S+S R
Sbjct: 2535 GDREEAHVPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAH----SISLVR 2590
Query: 1324 YELIVDKSRVGSKNPTKGK----IEQTQASEKKFYFGGSP------ISAQYANFTGCISN 1373
I+ ++ NP + K +E + Y GG P + +F GCI N
Sbjct: 2591 NRRII-TVQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMRRSFHGCIKN 2649
Query: 1374 AYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKS 1433
F ++E+ DF L C + +PK + + + K
Sbjct: 2650 LIF-----NLELLDFNSAVGHEQVDLDTCWLS--------------ERPKLAPDAEDSKL 2690
Query: 1434 KDAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKS 1493
P P C + + + A+Q+G T NS + K
Sbjct: 2691 LPEPRAFP-------------EQCVVDAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKL 2737
Query: 1494 QFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLW 1553
+ +RT +S G+I+Y++ Q + D+ L L GRL +MF++G + K+ +DG W
Sbjct: 2738 SVELSIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKW 2797
Query: 1554 HDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYS 1613
H V + G + +DG ++ ++G YLGG+ + + N +S
Sbjct: 2798 HTVKTDYVKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIG-NITHS 2856
Query: 1614 FSGCLSNLQLNGASITSAS--QTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFE 1671
C+ ++ +N + S F+V C+ E GTYF G ++ E + +
Sbjct: 2857 IPACIGDVTVNSKQLDKDSPVSAFTVNRCYAVAQE-GTYFDGSGYAALVKEGYKVQSDVN 2915
Query: 1672 IAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQS--LCDG 1729
I E R S +G L+ + + + + + +G+V+ VNNG + + PK + LCDG
Sbjct: 2916 ITLEFRTSSQNGVLLGISTAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDG 2975
Query: 1730 RWHRITVIRDSNVVQLDVDSEVNHVVGP-LNPKPIDHREPVFVGGVPESLLTPRLAPSKP 1788
+WH + + + + L VD P +D P++VGG P + L
Sbjct: 2976 KWHTLQANKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTS 3035
Query: 1789 FTGCIRHFVIDGHP----VSFSKAALVSGAVSINSCP 1821
F GC+R + P FS+A + G V ++SCP
Sbjct: 3036 FRGCLRKLALIKSPQVQSFDFSRAFELHG-VFLHSCP 3071
Score = 198 bits (503), Expect = 5e-50
Identities = 106/259 (40%), Positives = 137/259 (52%), Gaps = 29/259 (11%)
Query: 35 DIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHT----LSGECVPCDCNGNSNE 90
DI S+A+ + G + E C +G++ G C PC+C+G++ E
Sbjct: 691 DIASSNAIDLVVAADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAE 750
Query: 91 CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLAN-FAESCYRK 149
C + G C+ C NTTG HCE+CL G+ G+ RG P CQPC CPL +N F+ +C+
Sbjct: 751 C-NVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLN 809
Query: 150 NG--AVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTG 207
+G V C Y+G CERCA GYYGNP + G +C CDCSGN DP+ CD VTG
Sbjct: 810 DGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGH-CDSVTG 868
Query: 208 QCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC-----GGGPCDSVTGECLEEGFEP 262
+C CL NT G CERCA G+YGDA AKNC C C C TG C
Sbjct: 869 ECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLC------- 921
Query: 263 PTGMDC-PTIS---CDKCV 277
DC P ++ CD+C+
Sbjct: 922 ----DCKPNVTGQQCDQCL 936
Score = 125 bits (313), Expect = 5e-28
Identities = 76/226 (33%), Positives = 113/226 (50%), Gaps = 40/226 (17%)
Query: 65 EKCNAGFFH--TLSGE-CVPCDCNGN-----SNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
E+C G++ T+ GE CVPCDC+GN + C +G C+ C NT G HCE+C DG
Sbjct: 829 ERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADG 888
Query: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176
+ GD++ + C+ C C + + + C+ + G C C N G C++C GYYG
Sbjct: 889 FYGDAVTA--KNCRACECHVK--GSHSAVCHLETGL--CDCKPNVTGQQCDQCLHGYYG- 941
Query: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK 236
L G C+ C+CS + + C + GQC +C+ G +C+RCA G+Y A
Sbjct: 942 -LDSGHGCRPCNCSVAGS---VSDGCTD-EGQC-HCVPGVAGKRCDRCAHGFY--AYQDG 993
Query: 237 NCAVCNC--GGGPCDSVTGECLEEGFEPPTGMDCPT----ISCDKC 276
+C C+C CD TGEC+ CP + C++C
Sbjct: 994 SCTPCDCPHTQNTCDPETGECV-----------CPPHTQGVKCEEC 1028
Score = 90.5 bits (223), Expect = 1e-17
Identities = 59/197 (29%), Positives = 83/197 (42%), Gaps = 43/197 (21%)
Query: 79 CVPCDCNGNSNEC------------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
C C+C+ + +C G G C++C +NT G +CE C+DGY
Sbjct: 324 CEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRP 383
Query: 121 SIRGAPQFCQPC-PCPLPHLANFAESCYR-------KNGAV--RCICNENYAGPNCERCA 170
+ +P +PC PC + + + C + NG +C C E Y G C+RC
Sbjct: 384 H-KVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQ 442
Query: 171 PGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDE-VTGQCRNCLRNTTGFKCERCAPGYY 229
GY P TC C C N + DE TG C C N G C+RC PG+Y
Sbjct: 443 LGYKDYP-----TCVSCGC------NPVGSASDEPCTGPC-VCKENVEGKACDRCKPGFY 490
Query: 230 G-DARIAKNCAVCNCGG 245
+ + C+ C C G
Sbjct: 491 NLKEKNPRGCSECFCFG 507
Score = 90.5 bits (223), Expect = 1e-17
Identities = 62/188 (32%), Positives = 78/188 (41%), Gaps = 21/188 (11%)
Query: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
++C GF+ G C PCDC N C +G CV C +T G CE+C DG+ G
Sbjct: 981 DRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECV-CPPHTQGVKCEECEDGHWG---YD 1036
Query: 125 APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
A CQ C C L + + C G C C + G C++C+ GY P C
Sbjct: 1037 AEVGCQACNCSL--VGSTHHRCDVVTG--HCQCKSKFGGRACDQCSLGYRDFP-----DC 1087
Query: 185 KKCDCS--GNSDPNLIFED----CDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKN 237
CDC G S E C E TG C C N G +C C G + A
Sbjct: 1088 VPCDCDLRGTSGDACNLEQGLCGCVEETGAC-PCKENVFGPQCNECREGTFALRADNPLG 1146
Query: 238 CAVCNCGG 245
C+ C C G
Sbjct: 1147 CSPCFCSG 1154
Score = 72.4 bits (176), Expect = 4e-12
Identities = 41/133 (30%), Positives = 61/133 (45%), Gaps = 35/133 (26%)
Query: 153 VRCICNENYAGPNCERCAPGYYGNP-----LLIGSTCKKCDCSGNSDPNLIFEDC--DEV 205
++C C N G +C RC PGY+ P + G+TC+ C+C + +DC DE
Sbjct: 288 LQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKA------KDCYYDES 341
Query: 206 T----------------GQCRNCLRNTTGFKCERCAPGYYGDARIA----KNCAVCNCGG 245
G C NCL+NT G CE C GYY +++ + C CNC
Sbjct: 342 VAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNC-- 399
Query: 246 GPCDSVTGECLEE 258
P S++ C+++
Sbjct: 400 DPVGSLSSVCIKD 412
Score = 69.7 bits (169), Expect = 2e-11
Identities = 66/235 (28%), Positives = 90/235 (38%), Gaps = 59/235 (25%)
Query: 82 CDCNGNSNEC-LDGSGYCVHCQ--RNTTGEHCEKCLDGYIGDSIR----GAPQFCQPCPC 134
C C G+++ C D + + CQ NT GE C +C GY R + C+ C C
Sbjct: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329
Query: 135 PLPHLANFAESCYR-----------------KNGAVRCICNENYAGPNCERCAPGYYGNP 177
N A+ CY + G V C +N G NCE C GYY P
Sbjct: 330 -----HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYY-RP 383
Query: 178 LLIG----STCKKCDCS--GNSDPNLIFEDC------DEVTGQCRNCLRNTTGFKCERCA 225
+ C+ C+C G+ I +D + GQC C TG KC+RC
Sbjct: 384 HKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQC-PCKEGYTGEKCDRCQ 442
Query: 226 PGYYGDARIAKNCAVCNC---GGGPCDSVTGECL-EEGFEPPTGMDCPTISCDKC 276
GY + C C C G + TG C+ +E E +CD+C
Sbjct: 443 LGY----KDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGK--------ACDRC 485
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 169 bits (427), Expect = 3e-41
Identities = 95/260 (36%), Positives = 131/260 (50%), Gaps = 31/260 (11%)
Query: 21 CSRAASGD-----DNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTL 75
C+R A G P + +V P T + G ++C G H
Sbjct: 803 CNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPG--HWG 860
Query: 76 SGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP 135
C PC CNG++++C +G C++CQ T G +CE+CL GY GD I G+ C+PCPCP
Sbjct: 861 FPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCP 920
Query: 136 --LPHLANFAESCYRKNGAVR--CICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSG 191
FA SCY+ ++ C+C+ Y G C+ CA GY+GNP +G +C+ C C
Sbjct: 921 DGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHN 980
Query: 192 N---SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC--AVCN---- 242
N +DP E CD+ TG+C CL +T G C+ C GYYGDA + ++C VCN
Sbjct: 981 NIDTTDP----EACDKETGRCLKCLYHTEGEHCQFCRFGYYGDA-LQQDCRKCVCNYLGT 1035
Query: 243 ----CGGG--PCDSVTGECL 256
C G CD TG+CL
Sbjct: 1036 VQEHCNGSDCQCDKATGQCL 1055
Score = 113 bits (282), Expect = 2e-24
Identities = 62/174 (35%), Positives = 81/174 (46%), Gaps = 21/174 (12%)
Query: 76 SGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP 135
+G CD G+ + D +G C+ N G C +C G G P C+PC C
Sbjct: 769 TGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFG----FGPSGCKPCECH 824
Query: 136 LPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDP 195
L N C G +C C + C+RC PG++G P +C+ C C+G++D
Sbjct: 825 LQGSVN--AFCNPVTG--QCHCFQGVYARQCDRCLPGHWGFP-----SCQPCQCNGHAD- 874
Query: 196 NLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK--NCAVCNCGGGP 247
DCD VTG+C NC T G CERC GYYGD I +C C C GP
Sbjct: 875 -----DCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGP 923
Score = 88.6 bits (218), Expect = 5e-17
Identities = 79/248 (31%), Positives = 112/248 (45%), Gaps = 59/248 (23%)
Query: 82 CDCNGNSNEC--LDG---------SGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP---- 126
C C G+++EC +DG G+C+ C+ NT G +CE C+D Y R A
Sbjct: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
Query: 127 QFCQPCPCPLPHLA-NFAESCY----RKNGAVRCICNENYAGPNCERCAPGYYGNP---L 178
C+ C C ++ +F + Y +G V C N G NCE+C P YY +P +
Sbjct: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDI 389
Query: 179 LIGSTCKKCDC--SGNSDPNLIFEDCDEVT--------GQCRNCLRNTTGFKCERCAPGY 228
+ C++C C +G+ + + CD T GQCR C N G C+ C G+
Sbjct: 390 RDPNFCERCTCDPAGSQNEGI----CDSYTDFSTGLIAGQCR-CKLNVEGEHCDVCKEGF 444
Query: 229 YG----DARIAKNCAVCN-----CGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCV-- 277
Y D K+CA CN GG PCDS TG C + TG CD+C+
Sbjct: 445 YDLSSEDPFGCKSCA-CNPLGTIPGGNPCDSETGHCYCKRL--VTGQ-----HCDQCLPE 496
Query: 278 -WDLTDAL 284
W L++ L
Sbjct: 497 HWGLSNDL 504
Score = 83.2 bits (204), Expect = 2e-15
Identities = 62/205 (30%), Positives = 83/205 (40%), Gaps = 29/205 (14%)
Query: 76 SGECVPCDCNGNSNEC-LD----------GSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
S C C+CN +S C D G C CQ NT G +CE+C Y R
Sbjct: 329 SNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERD 388
Query: 125 A--PQFCQPCPCPLPHLANFAESCYRKNG------AVRCICNENYAGPNCERCAPGYYGN 176
P FC+ C C P + C A +C C N G +C+ C G+Y
Sbjct: 389 IRDPNFCERCTCD-PAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDL 447
Query: 177 PLLIGSTCKKCDCSG-NSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
CK C C+ + P CD TG C C R TG C++C P ++G +
Sbjct: 448 SSEDPFGCKSCACNPLGTIPG--GNPCDSETGHCY-CKRLVTGQHCDQCLPEHWGLSNDL 504
Query: 236 KNCAVCNC--GG---GPCDSVTGEC 255
C C+C GG C + +G+C
Sbjct: 505 DGCRPCDCDLGGALNNSCFAESGQC 529
Score = 79.7 bits (195), Expect = 2e-14
Identities = 42/105 (40%), Positives = 53/105 (50%), Gaps = 13/105 (12%)
Query: 154 RCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCL 213
+C C N G C RCAPG +G S CK C+C N C+ VTGQC +C
Sbjct: 791 QCQCRPNVVGRTCNRCAPGTFG---FGPSGCKPCECHLQGSVNAF---CNPVTGQC-HCF 843
Query: 214 RNTTGFKCERCAPGYYGDARIAKNCAVCNCGG--GPCDSVTGECL 256
+ +C+RC PG++G +C C C G CD VTGECL
Sbjct: 844 QGVYARQCDRCLPGHWG----FPSCQPCQCNGHADDCDPVTGECL 884
Score = 68.6 bits (166), Expect = 5e-11
Identities = 50/161 (31%), Positives = 69/161 (42%), Gaps = 25/161 (15%)
Query: 82 CDCNGNSNECLDGS----------GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQP 131
CD G+ NE + S G C C+ N GEHC+ C +G+ D P C+
Sbjct: 400 CDPAGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFY-DLSSEDPFGCKS 457
Query: 132 CPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG--NPLLIGSTCKKCD 188
C C PL + C + G C C G +C++C P ++G N L C+ CD
Sbjct: 458 CACNPLGTIPG-GNPCDSETG--HCYCKRLVTGQHCDQCLPEHWGLSNDL---DGCRPCD 511
Query: 189 CSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
C N C +GQC +C + G +C PGYY
Sbjct: 512 CDLGGALN---NSCFAESGQC-SCRPHMIGRQCNEVEPGYY 548
Score = 67.0 bits (162), Expect = 2e-10
Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 15/116 (12%)
Query: 67 CNAGFFHTLSGE---CVPCDCNG-----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYI 118
C GF+ S + C C CN N C +G+C +C+R TG+HC++CL +
Sbjct: 440 CKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHC-YCKRLVTGQHCDQCLPEHW 498
Query: 119 GDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
G + C+PC C L N SC+ ++G +C C + G C PGYY
Sbjct: 499 G--LSNDLDGCRPCDCDLGGALN--NSCFAESG--QCSCRPHMIGRQCNEVEPGYY 548
Score = 52.0 bits (123), Expect = 5e-06
Identities = 32/115 (27%), Positives = 49/115 (42%), Gaps = 13/115 (11%)
Query: 65 EKCNAGFFHTLSGE-CVPCDCNGNSN---ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
++C + SG C PC+CN + C + +G C C G C +C + + GD
Sbjct: 1066 DRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQC-QCMPGFGGRTCSECQELFWGD 1124
Query: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG 175
C+ C C + C + G +C+C E GP C++C GY G
Sbjct: 1125 P----DVECRACDCDPRGIET--PQCDQSTG--QCVCVEGVEGPRCDKCTRGYSG 1171
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 166 bits (419), Expect = 3e-40
Identities = 92/240 (38%), Positives = 125/240 (52%), Gaps = 40/240 (16%)
Query: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
++C AG+F S C PC CN + C +G C +C TTG +CE+C+DGY G+ G
Sbjct: 848 DRCLAGYFGFPS--CHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSG 905
Query: 125 APQFCQPCPCPLPHLAN--FAESCYRK--NGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
P C+PC CP +N FA SCY+ + V C C + Y G C C+ G+YGNP +
Sbjct: 906 QP--CRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRIS 963
Query: 181 GSTCKKCDCSGN---SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN 237
G+ C+ C C+ N +DP E C VTG+C CL NT G C+ C PG+YG A + +
Sbjct: 964 GAPCQPCACNNNIDVTDP----ESCSRVTGECLRCLHNTQGANCQLCKPGHYGSA-LNQT 1018
Query: 238 CAVCNC------------GGGP--CDSVTGECLEEGFEPPTGMDCPTISCDKCV---WDL 280
C C+C GGG CD VTG C P + ++CD+C W+L
Sbjct: 1019 CRRCSCHASGVSPMECPPGGGACLCDPVTGAC-------PCLPNVTGLACDRCADGYWNL 1071
Score = 109 bits (273), Expect = 2e-23
Identities = 66/201 (32%), Positives = 88/201 (43%), Gaps = 28/201 (13%)
Query: 79 CVPCDCNGNSNEC------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIR--G 124
C C CN +S+ C L G G C CQ NT G+HC++C + D ++
Sbjct: 329 CRSCSCNSHSSRCHFDMTTYLASGGLSG-GVCEDCQHNTEGQHCDRCRPLFYRDPLKTIS 387
Query: 125 APQFCQPCPCPLPHLANFAESCYRKNGAV-----RCICNENYAGPNCERCAPGYYGNPLL 179
P C PC C + + A+ +C+C EN G C++C P +YG
Sbjct: 388 DPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSAT 447
Query: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCA 239
C+ CDC N +L F CD TGQC CL TG CE C GY+G C+
Sbjct: 448 DPLGCQPCDC--NPLGSLPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWGLGNHLHGCS 504
Query: 240 VCNC--GG---GPCDSVTGEC 255
C+C GG C G+C
Sbjct: 505 PCDCDIGGAYSNVCSPKNGQC 525
Score = 90.5 bits (223), Expect = 1e-17
Identities = 61/192 (31%), Positives = 78/192 (40%), Gaps = 25/192 (13%)
Query: 60 LPPAAEKCNAGFFHTLSGECVPCDCNGNSN---ECLDGSGYCVHCQRNTTGEHCEKCLDG 116
LP A E+ L V C C+ + C G C C+ G C++C G
Sbjct: 747 LPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQC-QCKPLVVGRCCDRCSTG 805
Query: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAES-CYRKNGAVRCICNENYAGPNCERCAPGYYG 175
G C PC C H ++ C + G +C C+ +G C+RC GY+G
Sbjct: 806 SYDLGHHG----CHPCHC---HPQGSKDTVCDQVTG--QCPCHGEVSGRRCDRCLAGYFG 856
Query: 176 NPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
P +C C C N E CD TG C NC TTG CERC GYYG+
Sbjct: 857 FP-----SCHPCPC------NRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSG 905
Query: 236 KNCAVCNCGGGP 247
+ C C C P
Sbjct: 906 QPCRPCLCPDDP 917
Score = 89.0 bits (219), Expect = 4e-17
Identities = 154/794 (19%), Positives = 308/794 (38%), Gaps = 99/794 (12%)
Query: 67 CNAGFFHT-LSGECVPCDCNGNS---NECLDGSGYCV--------HCQRNTTGEHCEKCL 114
C G + + L+ C C C+ + EC G G C+ C N TG C++C
Sbjct: 1006 CKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCA 1065
Query: 115 DGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
DGY + + G + CQ C C P + + C + G +C C Y G C C YY
Sbjct: 1066 DGY-WNLVPG--RGCQSCDCD-PRTSQ-SSHCDQLTG--QCPCKLGYGGKRCSECQENYY 1118
Query: 175 GNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARI 234
G+P C CDC+ I CD TG CR C +G +C+RCA G+ +
Sbjct: 1119 GDP---PGRCIPCDCNRAGTQKPI---CDPDTGMCR-CREGVSGQRCDRCARGHSQEFPT 1171
Query: 235 AKNCAVCNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDALRLAALSIEE- 293
C +C S + ++ M+ + C D D LR IE
Sbjct: 1172 CLQCHLCFDQWDHTISSLSKAVQGLMRLAANMEDKRETLPVCEADFKD-LRGNVSEIERI 1230
Query: 294 GKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDV 353
K V + + + I L +L + ++ K I A+N LL D+
Sbjct: 1231 LKHPVFPSGKFLKVKDYHDSVRRQIMQLNEQL-KAVYEFQDLKDTIERAKNEADLLLEDL 1289
Query: 354 EELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKM-LYYGEEHELS 412
+E ++ ++ E++ H S E+ KI E ++ + ++L
Sbjct: 1290 QEEIDLQSSVLNASIADSSENIKKYYHISSSAEK------KINETSSTINTSANTRNDLL 1343
Query: 413 P--KEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELL---SQAESWQRLHNET 467
++ K L+ + L++I+ ++ + + L + ++ H +
Sbjct: 1344 TILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGDPGNVPCVPLPCGGALCTGRKGHRKC 1403
Query: 468 R--------TLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQ 519
R TL L++ + + + +L + + N + + + ++
Sbjct: 1404 RGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLKNQIESISEQAEVSKNNALQLREK 1463
Query: 520 QERVREQM----EVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVK 575
+R Q E +N+ + + L + +++ + I+ I
Sbjct: 1464 LGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIEKVANGVLDIHLPIPS-------- 1515
Query: 576 LSNLSNLSHDLV--QEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALD-ASNVYENI-- 630
NL+ +LV Q+ + +D + + N L+ + + + KA + A+N+ N+
Sbjct: 1516 ----QNLTDELVKIQKHMQLCEDYRTDENRLNEEADGAQKLLVKAKAAEKAANILLNLDK 1571
Query: 631 -VNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENL---LNQARE-------- 678
+N + +A T A +T ++ ++ I ++ ++++ + L A++
Sbjct: 1572 TLNQLQQAQITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELELAKQRSGLEDGL 1631
Query: 679 --LQAKAESSSDEAV-----ADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRL 731
LQ K + D AV A++++ G+L K ++ + A+ Q + + G ++ L
Sbjct: 1632 SLLQTKLQRHQDHAVNAKVQAESAQHQAGSL-EKEFVELKKQYAILQRKTSTTGLTKETL 1690
Query: 732 GQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEV 791
G+ + + + A + + T +T+ + +Q N + + D +R L +
Sbjct: 1691 GKVKQLKDAAEKLAGD----TEAKIRRITDLERKIQDL-----NLSRQAKADQLRILEDQ 1741
Query: 792 VPQLLDQLRTVEQK 805
V + +++ E+K
Sbjct: 1742 VVAIKNEIVEQEKK 1755
Score = 87.8 bits (216), Expect = 9e-17
Identities = 78/247 (31%), Positives = 103/247 (41%), Gaps = 55/247 (22%)
Query: 82 CDCNGNSNEC-----LDGS---------GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQ 127
C CNG+++EC + G G CV CQ NT G +CE+C D + R A
Sbjct: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAPWRPAAD 323
Query: 128 F----CQPCPC-PLPHLANFAESCYRKNGAVR---C-ICNENYAGPNCERCAPGYYGNPL 178
C+ C C +F + Y +G + C C N G +C+RC P +Y +PL
Sbjct: 324 LQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPL 383
Query: 179 LIGS---TCKKCDCS-----------GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
S C C+C +SDP L V GQC C N G KC++C
Sbjct: 384 KTISDPYACIPCECDPDGTISGGICVSHSDPAL-----GSVAGQCL-CKENVEGAKCDQC 437
Query: 225 APGYYG-DARIAKNCAVCNC---GGGP---CDSVTGECLEEGFEPPTGMDCPTISCDKCV 277
P +YG A C C+C G P CD TG+CL + TG C C
Sbjct: 438 KPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSY--VTGAHCE--ECTVGY 493
Query: 278 WDLTDAL 284
W L + L
Sbjct: 494 WGLGNHL 500
Score = 67.0 bits (162), Expect = 2e-10
Identities = 49/155 (31%), Positives = 65/155 (41%), Gaps = 21/155 (13%)
Query: 36 IEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNA------GFFHTLSGECVPCDCNGNSN 89
I G V DP S L + KC+ G T C PCDCN +
Sbjct: 403 ISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGS 462
Query: 90 ----ECLDGSGYCVHCQRNTTGEHCEKCLDGY--IGDSIRGAPQFCQPCPCPLPHLANFA 143
C +G C+ C TG HCE+C GY +G+ + G C PC C + ++
Sbjct: 463 LPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWGLGNHLHG----CSPCDCDIG--GAYS 515
Query: 144 ESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
C KNG +C C + G +C APGY+ PL
Sbjct: 516 NVCSPKNG--QCECRPHVTGRSCSEPAPGYFFAPL 548
Score = 64.3 bits (155), Expect = 1e-09
Identities = 51/191 (26%), Positives = 71/191 (37%), Gaps = 39/191 (20%)
Query: 154 RCICNENYAGPNCERCAPGYYGNPL-----LIGSTCKKCDCSGNS-----DPNLIFEDCD 203
+C+C N GPNCERC + P L + C+ C C+ +S D
Sbjct: 294 QCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGG 353
Query: 204 EVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN----CAVCNC------GGGPC----- 248
G C +C NT G C+RC P +Y D + C C C GG C
Sbjct: 354 LSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSD 413
Query: 249 ---DSVTGECL-EEGFEPPTGMDC----------PTISCDKCVWDLTDALRLAALSIEEG 294
SV G+CL +E E C + C C + +L ++ G
Sbjct: 414 PALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTG 473
Query: 295 KSGVLSVSSGA 305
+ LS +GA
Sbjct: 474 QCLCLSYVTGA 484
Score = 45.8 bits (107), Expect = 4e-04
Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 10/107 (9%)
Query: 20 ACSRAASGDDNAFP------FDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFH 73
AC R A G N P D + ++ T + LG +C ++
Sbjct: 1060 ACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYG 1119
Query: 74 TLSGECVPCDCNGNSNE---CLDGSGYCVHCQRNTTGEHCEKCLDGY 117
G C+PCDCN + C +G C C+ +G+ C++C G+
Sbjct: 1120 DPPGRCIPCDCNRAGTQKPICDPDTGMC-RCREGVSGQRCDRCARGH 1165
Score = 38.1 bits (87), Expect = 0.079
Identities = 28/102 (27%), Positives = 40/102 (39%), Gaps = 20/102 (19%)
Query: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
G+ KC G+ + C + GQC+ C G C+RC+ G Y C
Sbjct: 765 GAVACKCHPQGS-----VGSSCSRLGGQCQ-CKPLVVGRCCDRCSTGSYDLGH--HGCHP 816
Query: 241 CNCG-----GGPCDSVTGECLEEGFEPPTGMDCPTISCDKCV 277
C+C CD VTG+C P + CD+C+
Sbjct: 817 CHCHPQGSKDTVCDQVTGQC-------PCHGEVSGRRCDRCL 851
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 159 bits (402), Expect = 2e-38
Identities = 85/223 (38%), Positives = 118/223 (52%), Gaps = 29/223 (13%)
Query: 79 CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP--L 136
C PC CNG+++EC +G C+ C+ +T GEHCE+C+ G+ GD C+PCPCP
Sbjct: 874 CRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGP 933
Query: 137 PHLANFAESCYRK--NGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSD 194
+FA SC++ + + C C Y G CE CAPG++G+P G C+ C+CSGN D
Sbjct: 934 GSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNID 993
Query: 195 PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC---GGGP---- 247
P + + CD TGQC CL +T G C C PG++G A ++C C C G P
Sbjct: 994 P-MDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQA-ARQSCHRCTCNLLGTNPQQCP 1051
Query: 248 ------CDSVTGECLEEGFEPPTGMDCPTISCDKCV---WDLT 281
CD +G+C P + SCD+C W+LT
Sbjct: 1052 SPDQCHCDPSSGQC-------PCLPNVQGPSCDRCAPNFWNLT 1087
Score = 110 bits (275), Expect = 1e-23
Identities = 188/844 (22%), Positives = 313/844 (37%), Gaps = 138/844 (16%)
Query: 65 EKCNAGFFHTLS---GECVPCDCNGN-----SNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
E C G F S G C C+C+GN + C +G C+ C +T G HC C G
Sbjct: 966 EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPG 1025
Query: 117 YIGDSIRGAPQFCQPCPCPL----PHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172
+ G + R Q C C C L P + C+ + +C C N GP+C+RCAP
Sbjct: 1026 FHGQAAR---QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPN 1082
Query: 173 YYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA 232
++ L G C+ C C + C+E TGQC +C G C C ++GD
Sbjct: 1083 FWN--LTSGHGCQPCACHPSRARG---PTCNEFTGQC-HCRAGFGGRTCSECQELHWGDP 1136
Query: 233 RIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDALRLA 287
+ C C+C C TG C P + CD+C
Sbjct: 1137 GL--QCHACDCDSRGIDTPQCHRFTGHC---SCRPGVS----GVRCDQCA---------- 1177
Query: 288 ALSIEEGKSGVLSVSSGAAA-----HRHVNEINATIYLLKTKLSERENQYALRKIQINNA 342
G SG+ A R V ++ A L+ + E + L + ++
Sbjct: 1178 -----RGFSGIFPACHPCHACFGDWDRVVQDLAARTQRLEQRAQELQQTGVLGAFE--SS 1230
Query: 343 ENTMKSLLSDVEELVEKEN-QASRKGQLVQ------KESMDTINHASQLVEQAHDMRDKI 395
M+ L V+ +V N A+ QLV+ +E + H +QL D++D+
Sbjct: 1231 FWHMQEKLGIVQGIVGARNTSAASTAQLVEATEELRREIGEATEHLTQLEADLTDVQDEN 1290
Query: 396 QEINNKMLYYGEEH---ELSPKEISEKLVLAQ--KMLEEIRSRQPFFTQRELVDEEAD-E 449
N+ + + L+ +++ + L L + L S + +Q + A+
Sbjct: 1291 FNANHALSGLERDRLALNLTLRQLDQHLDLLKHSNFLGAYDSIRHAHSQSAEAERRANTS 1350
Query: 450 AYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQ--ALNYVRDAEDMNR 507
A + S + + T L Q +D+N+K Q AL + A + D+N
Sbjct: 1351 ALAVPSPVSNSASARHRTEALMDA---QKEDFNSKHMANQRALGKLSAHTHTLSLTDINE 1407
Query: 508 ATAARQRDH------------EKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDII 555
D + + R N + +T+ +L R T +EL +
Sbjct: 1408 LVCGAPGDAPCATSPCGGAGCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRAL 1467
Query: 556 KNASGI---YAEIDGAKSELQVKLS---NLSNLSHDLVQEAIDHAQDLQQEANELSRKLH 609
I AE SE Q + + +N S V++A Q+L Q + +
Sbjct: 1468 AEGGSILSRVAETRRQASEAQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQ-E 1526
Query: 610 SSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDES 669
+D + + + A+ V E + +E + A+ R V I + + +
Sbjct: 1527 GADPDSI---EMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRA 1583
Query: 670 ENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQ 729
E LL AR ++ AE +A + A+++ Q A+ G AQ
Sbjct: 1584 EQLLQDARRARSWAEDEKQKA-------------------ETVQAALEEAQRAQ-GIAQG 1623
Query: 730 RLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFD-------------SSAYNT 776
+ + T + +T +VQ+ A L++ + + D S A +T
Sbjct: 1624 AIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQLDALLEALKLKRAGNSLAAST 1683
Query: 777 AVNSARDAVRNLTEVVPQLL-----DQLRTVE--QKRPASNVSASIQRIRELIAQTRSVA 829
A +A A + + QLL DQ +TV+ +R A V A+ R +L + R +
Sbjct: 1684 AEETAGSA-QGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARDLL 1742
Query: 830 SKIQ 833
Q
Sbjct: 1743 QAAQ 1746
Score = 103 bits (258), Expect = 1e-21
Identities = 58/173 (33%), Positives = 81/173 (46%), Gaps = 25/173 (14%)
Query: 80 VPCDCNGN---SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136
+PC CN S+EC G C+ C+ G C+ C GY G P CQ C C
Sbjct: 781 LPCQCNPQGSLSSECNPHGGQCL-CKPGVVGRRCDLCAPGYYG----FGPTGCQACQC-- 833
Query: 137 PHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPN 196
H + C + +G +C+C G C+RC G +G P +C+ C C+G++D
Sbjct: 834 SHEGALSSLCEKTSG--QCLCRTGAFGLRCDRCQRGQWGFP-----SCRPCVCNGHAD-- 884
Query: 197 LIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARI--AKNCAVCNCGGGP 247
+C+ TG C C +T G CERC G++GD R+ C C C GP
Sbjct: 885 ----ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGP 933
Score = 97.4 bits (241), Expect = 1e-19
Identities = 60/205 (29%), Positives = 88/205 (42%), Gaps = 29/205 (14%)
Query: 76 SGECVPCDCNGNSNEC--------LDGS---GYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
S C C+C+G+++ C G+ G C CQ NT G HCE C + D +
Sbjct: 341 SHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKD 400
Query: 125 A--PQFCQPCPCPLPHLANFAESCYRKNGAV------RCICNENYAGPNCERCAPGYYGN 176
P C+ C C P + C + +C C E+ G C++C G++G
Sbjct: 401 LRDPAVCRSCDCD-PMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGL 459
Query: 177 PLLIGSTCKKCDCSGNSD-PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
+ C++C C+ P CD +G C C R TG C+RC PG++G +
Sbjct: 460 SISDRLGCRRCQCNARGTVPG--STPCDPNSGSC-YCKRLVTGRGCDRCLPGHWGLSHDL 516
Query: 236 KNCAVCNCGGG-----PCDSVTGEC 255
C C+C G CD TG+C
Sbjct: 517 LGCRPCDCDVGGALDPQCDEGTGQC 541
Score = 89.7 bits (221), Expect = 2e-17
Identities = 72/242 (29%), Positives = 100/242 (41%), Gaps = 47/242 (19%)
Query: 82 CDCNGNSNECLDGSGYCVH----------CQRNTTGEHCEKCLDGYIGDSIR----GAPQ 127
C C G+++EC G H C+ NT G +CE+C D Y R G
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSH 342
Query: 128 FCQPCPC-PLPHLANFAESCYRKNGAVR---CI-CNENYAGPNCERCAPGYYGNP---LL 179
C+ C C H +F + Y +G V C C N AG +CE C P +Y +P L
Sbjct: 343 ACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLR 402
Query: 180 IGSTCKKCDCS--GNSDPNLIFEDCDE----VTGQCRNCLRNTTGFKCERCAPGYYG-DA 232
+ C+ CDC G+ D D V+GQCR C + G +C++C G++G
Sbjct: 403 DPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCR-CKEHVVGTRCQQCRDGFFGLSI 461
Query: 233 RIAKNCAVCNC-------GGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCV---WDLTD 282
C C C G PCD +G C + G CD+C+ W L+
Sbjct: 462 SDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRG-------CDRCLPGHWGLSH 514
Query: 283 AL 284
L
Sbjct: 515 DL 516
Score = 83.6 bits (205), Expect = 2e-15
Identities = 55/168 (32%), Positives = 79/168 (47%), Gaps = 31/168 (18%)
Query: 79 CVPCDCNGNSNECLDG--------------SGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
C CDC+ ++ DG SG C C+ + G C++C DG+ G SI
Sbjct: 407 CRSCDCDPMGSQ--DGGRCDSHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFGLSISD 463
Query: 125 APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG-NPLLIGST 183
C+ C C + C +G+ C C G C+RC PG++G + L+G
Sbjct: 464 RLG-CRRCQCNARGTVPGSTPCDPNSGS--CYCKRLVTGRGCDRCLPGHWGLSHDLLG-- 518
Query: 184 CKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
C+ CDC G DP CDE TGQC +C ++ G +CE+ PGY+
Sbjct: 519 CRPCDCDVGGALDPQ-----CDEGTGQC-HCRQHMVGRRCEQVQPGYF 560
Score = 73.2 bits (178), Expect = 2e-12
Identities = 46/148 (31%), Positives = 67/148 (45%), Gaps = 23/148 (15%)
Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGST-CKKCDCSG 191
PC + + C G +C+C G C+ CAPGYYG G T C+ C CS
Sbjct: 782 PCQCNPQGSLSSECNPHGG--QCLCKPGVVGRRCDLCAPGYYG----FGPTGCQACQCSH 835
Query: 192 NSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG--GPCD 249
+ + C++ +GQC C G +C+RC G +G +C C C G C+
Sbjct: 836 EGALSSL---CEKTSGQCL-CRTGAFGLRCDRCQRGQWG----FPSCRPCVCNGHADECN 887
Query: 250 SVTGECLEEGFEPPTGMDCPTISCDKCV 277
+ TG CL G TG + C++C+
Sbjct: 888 THTGACL--GCRDHTGGE----HCERCI 909
Score = 58.9 bits (141), Expect = 4e-08
Identities = 38/120 (31%), Positives = 55/120 (45%), Gaps = 19/120 (15%)
Query: 65 EKCNAGFFHTLSGE---CVPCDCNGN-----SNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
++C GFF + C C CN S C SG C +C+R TG C++CL G
Sbjct: 450 QQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSC-YCKRLVTGRGCDRCLPG 508
Query: 117 YIGDS--IRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
+ G S + G C+PC C + + C G +C C ++ G CE+ PGY+
Sbjct: 509 HWGLSHDLLG----CRPCDCDVGGALD--PQC--DEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 56.2 bits (134), Expect = 3e-07
Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 18/138 (13%)
Query: 62 PAAEKCNAGFFHTLSGE-CVPCDCN---GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117
P+ ++C F++ SG C PC C+ C + +G C HC+ G C +C + +
Sbjct: 1074 PSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQC-HCRAGFGGRTCSECQELH 1132
Query: 118 IGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNP 177
GD C C C + C+R G C C +G C++CA G+ G
Sbjct: 1133 WGDP----GLQCHACDCDSRGIDT--PQCHRFTG--HCSCRPGVSGVRCDQCARGFSG-- 1182
Query: 178 LLIGSTCKKCD-CSGNSD 194
I C C C G+ D
Sbjct: 1183 --IFPACHPCHACFGDWD 1198
Score = 39.3 bits (90), Expect = 0.035
Identities = 68/328 (20%), Positives = 134/328 (40%), Gaps = 47/328 (14%)
Query: 348 SLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAH-DMRDKIQEINNKMLYYG 406
S+LS V E + ++A ++ Q ++D N + VEQA+ ++++ IQ + + + G
Sbjct: 1472 SILSRVAETRRQASEAQQRAQA----ALDKANASRGQVEQANQELQELIQSVKDFLNQEG 1527
Query: 407 EEH-----------ELSPKEISEKLV-LAQKMLEEIRSRQPF--FTQRELVD-EEADEAY 451
+ ELS +E++ LA + E +RS R + D A++
Sbjct: 1528 ADPDSIEMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLL 1587
Query: 452 ELLSQAESWQRLHNETRTLFPVVLEQLDDYN-----------AKLSDLQEALDQALNYVR 500
+ +A SW + LE+ A D ++ L Q +
Sbjct: 1588 QDARRARSWAEDEKQKAETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMA 1647
Query: 501 DAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASG 560
AE + R R + E ++ + +++ ST+ ++ + + E + +++ G
Sbjct: 1648 GAERALSSAGERARQLDALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLG 1707
Query: 561 IYAEIDGAKSE--------LQVKLSNLSNLSHDLVQEAIDHAQDLQQ-----EANELSRK 607
+ A +E Q + L + + DL+Q A D Q LQ+ E NE + +
Sbjct: 1708 DQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALE 1767
Query: 608 LHSSDMNGL---VQKALDASNVYENIVN 632
++ ++GL ++ L A N+ I N
Sbjct: 1768 SKAAQLDGLEARMRSVLQAINLQVQIYN 1795
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 157 bits (397), Expect = 9e-38
Identities = 86/216 (39%), Positives = 110/216 (50%), Gaps = 24/216 (11%)
Query: 79 CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPH 138
CV C CNG+S C +G C +C+ NT G HCEKC DGY GDS G CQPCPCP
Sbjct: 721 CVLCACNGHSETCDPETGVC-NCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCP--- 776
Query: 139 LANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLIGS---TCKKCDCSGNSD 194
+ + K V C C G CE C GY+G+PL C+ C CS N D
Sbjct: 777 -GGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNID 835
Query: 195 PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGD---ARIAKNCAVCNCG------- 244
PN + +C+ +TG+C C+ NT GF C+RC G++G+ A C CNC
Sbjct: 836 PNAV-GNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQ 894
Query: 245 GGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDL 280
C+ VTG+C E TG DC +CD ++L
Sbjct: 895 QSSCNPVTGQC--ECLPHVTGQDCG--ACDPGFYNL 926
Score = 155 bits (392), Expect = 3e-37
Identities = 187/837 (22%), Positives = 329/837 (39%), Gaps = 132/837 (15%)
Query: 48 PETSEPRVALGRLPPAAEKCNAGFFHT----LSGECVPCDCNGNSNECL---DGSGYCVH 100
PET P EKC+ G++ S +C PC C G S+ + C +
Sbjct: 735 PETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTN 794
Query: 101 CQRNTTGEHCEKCLDGYIGDSI--RGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-C 157
C TTG+ CE C DGY GD + G + C+ C C N +C R G C+ C
Sbjct: 795 CPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTG--ECLKC 852
Query: 158 NENYAGPNCERCAPGYYGNPLL--IGSTCKKCDCS--GNSDPNLIFEDCDEVTGQCRNCL 213
N AG C+RC G++GNPL CK C+C+ G C+ VTGQC CL
Sbjct: 853 IYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQ---SSCNPVTGQC-ECL 908
Query: 214 RNTTGFKCERCAPGYYGDARIAKNCAVCNC-----GGGPCDSVTGECLEEGFEPPTGMDC 268
+ TG C C PG+Y + + + C C+C G CD TG+C E TG C
Sbjct: 909 PHVTGQDCGACDPGFY-NLQSGQGCERCDCHALGSTNGQCDIRTGQC--ECQPGITGQHC 965
Query: 269 PTI----------SCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHR--------- 309
C C D +LS++ G G +R
Sbjct: 966 ERCEVNHFGFGPEGCKPC-----DCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYF 1020
Query: 310 ------HVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQA 363
E A L+K K+++ ++++ E+ + +L + E + ++ +
Sbjct: 1021 YNRSWPGCQECPACYRLVKDKVAD-------HRVKLQELESLIANLGTGDEMVTDQAFED 1073
Query: 364 SRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLA 423
K ++E MD + A + + ++ D++Q +NN + + I E LA
Sbjct: 1074 RLKE--AEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLA 1131
Query: 424 QKMLEEIRSRQPF--FTQRELVDEEADEAYELLSQAES------WQRLHNETRTLFPVVL 475
++ + + + REL + A ++Q ES L E R L
Sbjct: 1132 EQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLLAEEARKLAERHK 1191
Query: 476 EQLDDYNAKLSDLQEALDQALNYVR-----------DAEDMNRATAARQ---RDHEKQQE 521
++ DD + +A N + + E++NR + +D EKQ
Sbjct: 1192 QEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQAKNISQDLEKQAA 1251
Query: 522 RVREQMEVVNMSLSTSADSLTTPRLTLSELDD--IIKNASGIYAEIDGAKSELQVKLSNL 579
RV E+ + A + LS LD + A+ I E + + + KL +
Sbjct: 1252 RVHEEAK----RAGDKAVEIYASVAQLSPLDSETLENEANNIKMEAENLEQLIDQKLKDY 1307
Query: 580 SNLSHDL------VQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNY 633
+L D+ V+ ++ + QQ A++L + ++ KAL
Sbjct: 1308 EDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAA-------KAL------------ 1348
Query: 634 VSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVAD 693
EA + L + I + + D ++ +K +E L + + + + ++E +
Sbjct: 1349 AEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAIN-QTITEANEKTRE 1407
Query: 694 TSRRVGGALARKSALKT------RLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTME 747
+ +G A A + K R++ AV++ + + +A++ + + E N +
Sbjct: 1408 AQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQ 1467
Query: 748 VQQATAPMANNLTNWSQNLQ---HFDSSAYNTAVNS--ARDAVRNLTEVVPQLLDQL 799
+Q+A + + Q++ +A +N+ A+++V +L ++ LL+QL
Sbjct: 1468 LQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLLSIINDLLEQL 1524
Score = 133 bits (334), Expect = 2e-30
Identities = 183/890 (20%), Positives = 336/890 (37%), Gaps = 167/890 (18%)
Query: 65 EKCNAGFFHTLSGE------CVPCDCNGNSN-----ECLDGSGYCVHCQRNTTGEHCEKC 113
E C+ G+F G C C C+ N + C +G C+ C NT G +C++C
Sbjct: 805 ELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRC 864
Query: 114 LDGYIGDSIRGAP-QFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172
DG+ G+ + P C+ C C L SC G +C C + G +C C PG
Sbjct: 865 KDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTG--QCECLPHVTGQDCGACDPG 922
Query: 173 YYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA 232
+Y L G C++CDC N CD TGQC C TG CERC ++G
Sbjct: 923 FYN--LQSGQGCERCDCHALGSTN---GQCDIRTGQCE-CQPGITGQHCERCEVNHFGFG 976
Query: 233 RIAKNCAVCNC-----------GGGPCDSVTG-------ECLEEGFEPPTGMDCPTISCD 274
+ C C+C G C+ G +C E F + C C
Sbjct: 977 --PEGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQ--ECP 1032
Query: 275 KCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYAL 334
C + D + + ++E +S + ++ +G + + + K +ERE L
Sbjct: 1033 ACYRLVKDKVADHRVKLQELESLIANLGTGD------EMVTDQAFEDRLKEAEREVMDLL 1086
Query: 335 RKIQ---------------INNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTIN 379
R+ Q +NN ++ S L ++ +E+ + + + + + I
Sbjct: 1087 REAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVENTERLIE 1146
Query: 380 HASQLVEQAH--------DMRDKIQEINNKMLYYGEEHELSP--KEISEKLVLAQKMLEE 429
AS+ +E+A + + NN L E +L+ K+ ++ +V K +
Sbjct: 1147 IASRELEKAKVAAANVSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTAND 1206
Query: 430 IRSRQPFFTQRELVDE-----EADEAYELLSQAESWQ--------RLHNETRTLFPVVLE 476
+ R L E E +E QA++ R+H E + +E
Sbjct: 1207 TSTEAYNLLLRTLAGENQTAFEIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVE 1266
Query: 477 QLDDYNAKLSDL-QEALDQALNYVR-DAEDMNRATAARQRDHEKQQERVR-EQMEVVNMS 533
A+LS L E L+ N ++ +AE++ + + +D+E +E +R +++EV N+
Sbjct: 1267 IYASV-AQLSPLDSETLENEANNIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLL 1325
Query: 534 LSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDH 593
+ T A + A D AK+ L +EA
Sbjct: 1326 EKGKTEQQT---------------ADQLLARADAAKA---------------LAEEAAKK 1355
Query: 594 AQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYD 653
+D QEAN++ L D ++ D E + + N+T A T
Sbjct: 1356 GRDTLQEANDILNNLKDFD-----RRVNDNKTAAEEALRKIPAINQTITEANEKTREAQQ 1410
Query: 654 AVSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLS 713
A+ E++N ++A + + + ++ A+ R A + L ++
Sbjct: 1411 ALGSAAAD----ATEAKNKAHEAERIASAVQKNATSTKAEAER----TFAEVTDLDNEVN 1462
Query: 714 DAVKQLQAAER------GDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQ 767
+ +KQLQ AE+ DA Q + + + ++ A + ++A
Sbjct: 1463 NMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKA---------------- 1506
Query: 768 HFDSSAYNTAVNSARDAVRNLTEVVPQL----LDQLRTVEQKRPASNVSASIQRIRELIA 823
+V S + +L E + QL L++L +E + + + ++
Sbjct: 1507 -------KNSVTSLLSIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVS 1559
Query: 824 QTRSVASKIQVSMMFDGQSAVEV-HSRTSMDDLKAFTSLSLYMKPPVKRP 872
+ A K + ++M + E+ +++D++ + P +++P
Sbjct: 1560 DLENEAKKQEAAIMDYNRDIEEIMKDIRNLEDIRKTLPSGCFNTPSIEKP 1609
Score = 115 bits (289), Expect = 3e-25
Identities = 62/181 (34%), Positives = 88/181 (48%), Gaps = 28/181 (15%)
Query: 76 SGECVPCDCNGNSNECL---------DGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
+ EC+PCDCNG S EC G+C +CQ NT G HCE+C + + G
Sbjct: 336 ASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFR---LGNN 392
Query: 127 QFCQPCPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCK 185
+ C C C P+ L+ +S RC C G C+RC PG++ L + C+
Sbjct: 393 EACSSCHCSPVGSLSTQCDS------YGRCSCKPGVMGDKCDRCQPGFHS---LTEAGCR 443
Query: 186 KCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCG 244
C C DP+ ++C+ TG+C C N GF CERC PG++ ++ + C C C
Sbjct: 444 PCSC----DPSGSIDECNIETGRC-VCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCF 498
Query: 245 G 245
G
Sbjct: 499 G 499
Score = 80.1 bits (196), Expect = 2e-14
Identities = 76/277 (27%), Positives = 112/277 (40%), Gaps = 53/277 (19%)
Query: 27 GDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAE------KCNAGFFHTLSGECV 80
G +A+ FD ++ Q+ ++ RV L RL + K +++ +S V
Sbjct: 227 GRPSAYNFD----NSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAV 282
Query: 81 P--CDCNGNSNECLDGS--GYCVHCQRNTTGEHCEKCLDGYIGDSIRGA----PQFCQPC 132
C CNG+++EC+ +C+ NT G CEKCL + R A C PC
Sbjct: 283 GGRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPC 342
Query: 133 PC-PLPHLANFAESCYRKNG-AVRCI-CNENYAGPNCERCAPGYY--GNPLLIGSTCKKC 187
C F YR G C C +N G +CERC ++ GN C C
Sbjct: 343 DCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGN----NEACSSC 398
Query: 188 DCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG- 246
C S + CD G+C +C G KC+RC PG++ + C C+C
Sbjct: 399 HC---SPVGSLSTQCDSY-GRC-SCKPGVMGDKCDRCQPGFH--SLTEAGCRPCSCDPSG 451
Query: 247 ---PCDSVTGECL----EEGFEPPTGMDCPTISCDKC 276
C+ TG C+ EGF +C++C
Sbjct: 452 SIDECNIETGRCVCKDNVEGF-----------NCERC 477
Score = 75.1 bits (183), Expect = 6e-13
Identities = 43/107 (40%), Positives = 52/107 (48%), Gaps = 11/107 (10%)
Query: 155 CICNENYAGPNCERCAPGYYGNPLLIG--STCKKCDCSGNSDPNLIFEDCDEVTGQCRNC 212
C C Y G CE C GY +G S C C C+G+S E CD TG C NC
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHS------ETCDPETGVC-NC 742
Query: 213 LRNTTGFKCERCAPGYYGD--ARIAKNCAVCNCGGGPCDSVTGECLE 257
NT G CE+C+ GYYGD A + +C C C GG +V + E
Sbjct: 743 RDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKE 789
Score = 37.0 bits (84), Expect = 0.18
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 3/44 (6%)
Query: 65 EKCNAGFFHTLSGE---CVPCDCNGNSNECLDGSGYCVHCQRNT 105
E+C GFF+ S C PC C G+S+ C + GY V+ +T
Sbjct: 475 ERCKPGFFNLESSNPRGCTPCFCFGHSSVCTNAVGYSVYSISST 518
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 145 bits (365), Expect = 5e-34
Identities = 82/210 (39%), Positives = 104/210 (49%), Gaps = 26/210 (12%)
Query: 65 EKCNAGFFHTLS-----GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
E C G+ + CVPC CN + C +G CV C +T G CE+CL G+ G
Sbjct: 685 ESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDPNTGICV-CSHHTEGPSCERCLPGFYG 742
Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPL 178
+ G CQPCPCP A + ++ V C C G CE C G++G+PL
Sbjct: 743 NPFAGQADDCQPCPCP----GQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPL 798
Query: 179 -LIG--STCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA--- 232
L G C +C CSGN DPN + +CD ++G C CL NTTG CE C G+YG A
Sbjct: 799 GLFGHPQPCHQCQCSGNVDPNAV-GNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAP 857
Query: 233 RIAKNCAVCNCGGG-------PCDSVTGEC 255
R A C C+C PCD VTG+C
Sbjct: 858 RPADKCMPCSCHPQGSVSEQMPCDPVTGQC 887
Score = 118 bits (295), Expect = 6e-26
Identities = 193/865 (22%), Positives = 321/865 (37%), Gaps = 118/865 (13%)
Query: 29 DNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPA-----AEKCNAGFFHTLSG------ 77
D+ P G SA PE+ E V PP E C+ GFF G
Sbjct: 750 DDCQPCPCPGQSAC--TTIPESRE--VVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQ 805
Query: 78 ECVPCDCNGNSN-----ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP-QFCQP 131
C C C+GN + C SG+C+ C NTTG+HCE C +G+ G ++ P C P
Sbjct: 806 PCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMP 865
Query: 132 CPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCS- 190
C C + C G +C C + +C RC PG++ L G C+ C C
Sbjct: 866 CSCHPQGSVSEQMPCDPVTG--QCSCLPHVTARDCSRCYPGFF--DLQPGRGCRSCKCHP 921
Query: 191 -GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCD 249
G+ + + C TGQC C TG C+RC G++G + K C C C P
Sbjct: 922 LGSQE-----DQCHPKTGQC-TCRPGVTGQACDRCQLGFFGFS--IKGCRACRC--SPLG 971
Query: 250 SVTGECLEEGFEPPTGMDCPTI---SCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAA 306
+ + +C E G T + P CD+C D L A +G S A
Sbjct: 972 AASAQCHENG----TCVCRPGFEGYKCDRC----HDNFFLTA----DGTHCQQCPSCYAL 1019
Query: 307 AHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRK 366
++ A + L + L + + I E + L +R+
Sbjct: 1020 VKEEAAKLKARLTLTEGWLQGSDCGSPWGPLDILLGEAPRGDVYQGHHLL-----PGARE 1074
Query: 367 GQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKM 426
L Q S++ A+ R+++Q +N + + ++++ + +
Sbjct: 1075 AFLEQMMSLEGAVKAA---------REQLQRLNKGARCAQAGSQKTCTQLADLEAVLESS 1125
Query: 427 LEEIRSRQPFFTQRELVDEEADEAYE---LLSQAESWQRLHNETRT-LFPVVLEQLDDYN 482
EEI E+ E + + L ++A + R H +T T + L N
Sbjct: 1126 EEEILHAAAILASLEIPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRALLASN 1185
Query: 483 AKLSDLQEALD--QALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS 540
+ L L+ AL RD ED + A Q+ V + E V ++ +
Sbjct: 1186 TSYALLWNLLEGRVALETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESV-LATVQQVGA 1244
Query: 541 LTTPRLTLSELDDIIKNASGIYAEIDGAKSE-LQVKLSNLSNLSHDLVQEAIDHAQDLQQ 599
T P L L + S AE G K++ L+ +++ +++ + + AQ +
Sbjct: 1245 DTAPYLALLASPGALPQKS--RAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQATLR 1302
Query: 600 EANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGID 659
+ L+ KLH L Q S + + A + + + G+
Sbjct: 1303 QTEPLT-KLHQEARAALTQ---------------ASSSVQAATVTVMGARTLLADLEGMK 1346
Query: 660 TQIIYHKDESENLLNQARELQAKAESSSDEAVADT-------SRRVGGALARKSALKTR- 711
Q KD++ LQ KA+S SD +ADT R +G A S+ K +
Sbjct: 1347 LQFPRPKDQA--------ALQRKADSVSDRLLADTRKKTKQAERMLGNAAPLSSSAKKKG 1398
Query: 712 ------LSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQN 765
D+ K +A R Q SRL ++ QQ A A
Sbjct: 1399 REAEVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQASQQVLASEARRQELEEAE 1458
Query: 766 LQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVE-QKRPASNVSA---SIQRIREL 821
S + +R ++ E + +LL +L +++ + PA ++ +++R+R
Sbjct: 1459 RVGAGLSEMEQQIRESRISLEKDIETLSELLARLGSLDTHQAPAQALNETQWALERLRLQ 1518
Query: 822 IAQTRSVASKIQVSMMFDGQSAVEV 846
+ S+ K+ + Q +++
Sbjct: 1519 LGSPGSLQRKLSLLEQESQQQELQI 1543
Score = 95.9 bits (237), Expect = 3e-19
Identities = 69/208 (33%), Positives = 92/208 (44%), Gaps = 29/208 (13%)
Query: 82 CDCNGNSNEC---LDGSGYCVHCQRNTTGEHCEKCL----DGYIGDSIRGAPQFCQPCPC 134
C CNG+++EC + G C CQ NTTG CE+CL D A C PC C
Sbjct: 271 CKCNGHASECGPDVAGQLAC-RCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC 329
Query: 135 P-LPHLANFAESCYRKNG-AVRC-ICNENYAGPNCERCAPGYY-GNPLLIGSTCKKCDCS 190
F +R G RC C ++ AGP+CERC +Y +P + C+ CDC
Sbjct: 330 SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRM---PCQPCDCQ 386
Query: 191 GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG--PC 248
+L CD+ TG C C TG+KC+RC PG++ + CN G C
Sbjct: 387 SAGSLHL---QCDD-TGTCA-CKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTC 441
Query: 249 DSVTGECLEEGFEPPTGMDCPTISCDKC 276
D +G C P + CD+C
Sbjct: 442 DPRSGRC-------PCKENVEGNLCDRC 462
Score = 93.2 bits (230), Expect = 2e-18
Identities = 55/178 (30%), Positives = 76/178 (42%), Gaps = 26/178 (14%)
Query: 78 ECVPCDCNGNSNECL---------DGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF 128
EC+PC+C+G S EC G C HC+ +T G HCE+C + + R
Sbjct: 323 ECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPR---MP 379
Query: 129 CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCD 188
CQPC C + C + C C G C+RC PG++ L C+ C
Sbjct: 380 CQPCDC--QSAGSLHLQC---DDTGTCACKPTVTGWKCDRCLPGFHS---LSEGGCRPCT 431
Query: 189 CSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCGG 245
C +P + CD +G+C C N G C+RC PG + C+ C C G
Sbjct: 432 C----NPAGSLDTCDPRSGRC-PCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYG 484
Score = 64.3 bits (155), Expect = 1e-09
Identities = 38/98 (38%), Positives = 46/98 (46%), Gaps = 18/98 (18%)
Query: 155 CICNENYAGPNCERCAPGY-----YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQC 209
C C Y G CE CAPGY G P ++C C C+ + CD TG C
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPY---ASCVPCTCNQHG-------TCDPNTGIC 722
Query: 210 RNCLRNTTGFKCERCAPGYYGD--ARIAKNCAVCNCGG 245
C +T G CERC PG+YG+ A A +C C C G
Sbjct: 723 -VCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPG 759
Score = 63.9 bits (154), Expect = 1e-09
Identities = 44/144 (30%), Positives = 62/144 (43%), Gaps = 30/144 (20%)
Query: 151 GAVRCICNENYAGPNCERCAPGYYGNPLLIGST-----CKKCDCSGNSDPNLIFEDCDEV 205
G + C C N G +CERC P + P G+ C C+CSG S+ +
Sbjct: 286 GQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRS 345
Query: 206 T---GQCRNCLRNTTGFKCERCAPGYY-GDARIAKNCAVCNCGGG-----PCDSVTGECL 256
T G+C +C +T G CERC +Y D R+ C C+C CD TG C
Sbjct: 346 TGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--CQPCDCQSAGSLHLQCDD-TGTCA 402
Query: 257 EEGFEPPTGMDCPTIS---CDKCV 277
+ PT++ CD+C+
Sbjct: 403 CK----------PTVTGWKCDRCL 416
Score = 43.1 bits (100), Expect = 0.002
Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 65 EKCNAGFFHTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 122
++C GF G C PC CN G+ + C SG C C+ N G C++C G
Sbjct: 413 DRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGRC-PCKENVEGNLCDRCRPGTFNLQP 471
Query: 123 RGAPQFCQPCPC 134
P C C C
Sbjct: 472 HN-PAGCSSCFC 482
>gi|157419130 laminin, alpha 4 isoform 3 precursor [Homo sapiens]
Length = 120
Score = 135 bits (341), Expect = 3e-31
Identities = 65/65 (100%), Positives = 65/65 (100%)
Query: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
Sbjct: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
Query: 61 PPAAE 65
PPAAE
Sbjct: 61 PPAAE 65
>gi|157419128 laminin, alpha 4 isoform 3 precursor [Homo sapiens]
Length = 120
Score = 135 bits (341), Expect = 3e-31
Identities = 65/65 (100%), Positives = 65/65 (100%)
Query: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
Sbjct: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
Query: 61 PPAAE 65
PPAAE
Sbjct: 61 PPAAE 65
>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
Length = 1193
Score = 134 bits (336), Expect = 1e-30
Identities = 177/807 (21%), Positives = 319/807 (39%), Gaps = 137/807 (16%)
Query: 77 GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136
G C+PC+C G C +G C N E C C G+ D P+ C+PCPC
Sbjct: 411 GTCIPCNCQGGG-ACDPDTGDCYSGDENPDIE-CADCPIGFYNDP--HDPRSCKPCPCH- 465
Query: 137 PHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLIGST---CKKCDCSGN 192
F+ S + V C C G CE CA GY+G+P C+ C C+ N
Sbjct: 466 ---NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN 522
Query: 193 SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGD---ARIAKNCAVCNC---GGG 246
DP+ +CD +TG+C C+ NT G C++C GY+GD A C CNC G
Sbjct: 523 VDPSAS-GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581
Query: 247 P--CDSVTGECL-EEGFEPPT----GMDCPT------ISCDKCVWDLTDALRLAAL-SIE 292
P C S G C+ + GF P CP I D+ + L R+ AL S
Sbjct: 582 PVGCRS-DGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFMQQLQ---RMEALISKA 637
Query: 293 EGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSE-RENQYALRKIQINNAENTMKSLLS 351
+G GV+ + + + I L ++SE L+ ++ + EN+ +S L
Sbjct: 638 QGGDGVVPDTELEGRMQQAEQALQDI-LRDAQISEGASRSLGLQLAKVRSQENSYQSRLD 696
Query: 352 DVEELVEK---------------------------ENQAS-------------------- 364
D++ VE+ E++AS
Sbjct: 697 DLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKS 756
Query: 365 --RKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVL 422
++ + + +++ ++ QL + D + + K L+ G + + L
Sbjct: 757 LAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGL 816
Query: 423 AQKMLEEIRSRQPFFTQRELVDEEADEAYE-LLSQAESWQRLHNETRTLFPVVLEQLDDY 481
+K+ + Q + + EAD +Y+ L +S RL + F V E+
Sbjct: 817 VEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQV--EEAKRI 874
Query: 482 NAKLSDLQEALDQALN-YVRDAEDM-NRATAARQ--RDHEKQQERVREQMEVVNMSLSTS 537
K L + + ++ + R +++ N A+Q ++ + +E+ + + N++ S +
Sbjct: 875 KQKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRA 934
Query: 538 ADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDL 597
++L+ T E++ I+KN ++D K+E + + LS +S V +A D Q
Sbjct: 935 QEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQK-VSDASDKTQQA 993
Query: 598 QQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSG 657
++ + + NG + +S + + I + EAN TA+ AL + S
Sbjct: 994 ERALGSAAADAQRA-KNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSE 1052
Query: 658 I----------DTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGAL----- 702
+ + + + D + ++ +A+++ +A+++ + DT + G L
Sbjct: 1053 MREVEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNAG-VTIQDTLNTLDGLLHLMDQ 1111
Query: 703 -------------ARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQ 749
+ S KT+++ ++ + + A+Q+ G L+ + +V+
Sbjct: 1112 PLSVDEEGLVLLEQKLSRAKTQINSQLRPMMSELEERARQQRGHLHLLETSIDGILADVK 1171
Query: 750 QATAPMANNLTNWSQNLQHFDSSAYNT 776
NL N NL YNT
Sbjct: 1172 --------NLENIRDNL---PPGCYNT 1187
Score = 95.9 bits (237), Expect = 3e-19
Identities = 62/182 (34%), Positives = 82/182 (45%), Gaps = 36/182 (19%)
Query: 82 CDCNGNSNECL--------DGSGY-CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPC 132
CDCNG S +C+ G+G+ C++C NT G HCEKC +G+ R C PC
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR---CLPC 84
Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC-------- 184
C + R + + RC C G C+RC PG++ +L + C
Sbjct: 85 NC-----NSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH---MLTDAGCTQDQRLLD 136
Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNC 243
KCDC DP I CD G+C C TG +C+RC GYY D + C C C
Sbjct: 137 SKCDC----DPAGIAGPCD--AGRC-VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Query: 244 GG 245
G
Sbjct: 190 YG 191
Score = 73.9 bits (180), Expect = 1e-12
Identities = 49/140 (35%), Positives = 63/140 (45%), Gaps = 23/140 (16%)
Query: 65 EKCNAGFF-HTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
EKC GF+ H C+PC+CN G+ + D SG C C+ TG C++CL G+ +
Sbjct: 66 EKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRC-SCKPGVTGARCDRCLPGFHMLT 124
Query: 122 IRGAPQ----FCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY--- 174
G Q C C A A C A RC+C G C+RC GYY
Sbjct: 125 DAGCTQDQRLLDSKCDC---DPAGIAGPC----DAGRCVCKPAVTGERCDRCRSGYYNLD 177
Query: 175 -GNPLLIGSTCKKCDCSGNS 193
GNP C +C C G+S
Sbjct: 178 GGNP----EGCTQCFCYGHS 193
Score = 70.5 bits (171), Expect = 1e-11
Identities = 146/691 (21%), Positives = 244/691 (35%), Gaps = 142/691 (20%)
Query: 154 RCICNENYAGPNCERCAPGYYGNPLLIG--STCKKCDC--------------SGNSDPNL 197
+CIC Y G C+ CA GY + +G TC C+C SG+ +P++
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
Query: 198 IFEDC-------------------------------DEVTGQCRNCLRNTTGFKCERCAP 226
DC +EV C NC TG +CE CA
Sbjct: 441 ECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV--CNNCPPGVTGARCELCAD 498
Query: 227 GYYGDA----RIAKNCAVCNC-------GGGPCDSVTGECLEEGFEPPTGMDCPTIS--- 272
GY+GD + C C C G CD +TG CL + G+ C
Sbjct: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCL-KCIHNTAGIYCDQCKAGY 557
Query: 273 ---------CDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKT 323
DKC + + + + V G H Y
Sbjct: 558 FGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAFSCPACY---- 613
Query: 324 KLSERENQYALRKIQINNAENTMKSLLSDVE--ELVEKENQASRKGQLVQKESMDTINHA 381
NQ ++ Q M++L+S + + V + + + Q ++ D + A
Sbjct: 614 ------NQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDA 667
Query: 382 SQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRE 441
+ + ++ ++ ++ Y + + L + +R TQ +
Sbjct: 668 QISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQ 727
Query: 442 LVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDY---NAKLSDLQEALDQALNY 498
LS AES L N + D Y N S QEA A ++
Sbjct: 728 ------------LSLAESEASLGNTN-------IPASDHYVGPNGFKSLAQEATRLAESH 768
Query: 499 VRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRL------TLSELD 552
V A +M + T + ++ VR+ + S S S D L T S
Sbjct: 769 VESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQ 828
Query: 553 DIIKNASGIYAEIDGAKS-----ELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK 607
+ + A+ AEI+ +S L +S L +S Q ++ A+ ++Q+A+ LS
Sbjct: 829 QLTREAT--QAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQ--VEEAKRIKQKADSLSSL 884
Query: 608 L-HSSDMNGLVQKAL-----DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQ 661
+ D QK L +A + +N + ++++ A R +A+S +
Sbjct: 885 VTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALS-MGNA 943
Query: 662 IIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQA 721
Y E E++L RE + ++ EA A+ R S + ++SDA + Q
Sbjct: 944 TFY---EVESILKNLREFDLQVDNRKAEAEE--------AMKRLSYISQKVSDASDKTQQ 992
Query: 722 AER--GDAQQRLGQSRLITEEANRTTMEVQQ 750
AER G A +++ EA + E++Q
Sbjct: 993 AERALGSAAADAQRAKNGAGEALEISSEIEQ 1023
Score = 31.2 bits (69), Expect = 9.6
Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 7/65 (10%)
Query: 65 EKCNAGFFHTLSGE---CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
++C +G+++ G C C C G+S C + Y VH +T + +DG+
Sbjct: 167 DRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQD----VDGWKAVQ 222
Query: 122 IRGAP 126
G+P
Sbjct: 223 RNGSP 227
>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
Length = 1111
Score = 132 bits (332), Expect = 3e-30
Identities = 153/648 (23%), Positives = 263/648 (40%), Gaps = 97/648 (14%)
Query: 77 GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136
G C+PC+C G C +G C N E C C G+ D P+ C+PCPC
Sbjct: 411 GTCIPCNCQGGG-ACDPDTGDCYSGDENPDIE-CADCPIGFYNDP--HDPRSCKPCPCH- 465
Query: 137 PHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLIGST---CKKCDCSGN 192
F+ S + V C C G CE CA GY+G+P C+ C C+ N
Sbjct: 466 ---NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN 522
Query: 193 SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGD---ARIAKNCAVCNC---GGG 246
DP+ +CD +TG+C C+ NT G C++C GY+GD A C CNC G
Sbjct: 523 VDPSAS-GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581
Query: 247 P--CDSVTGECL-EEGFEPPT----GMDCPT------ISCDKCVWDLTDALRLAAL-SIE 292
P C S G C+ + GF P CP I D+ + L R+ AL S
Sbjct: 582 PVGCRS-DGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFMQQLQ---RMEALISKA 637
Query: 293 EGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSE-RENQYALRKIQINNAENTMKSLLS 351
+G GV+ + + + I L ++SE L+ ++ + EN+ +S L
Sbjct: 638 QGGDGVVPDTELEGRMQQAEQALQDI-LRDAQISEGASRSLGLQLAKVRSQENSYQSRLD 696
Query: 352 DVEELVEK---------------------------ENQAS-------------------- 364
D++ VE+ E++AS
Sbjct: 697 DLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKS 756
Query: 365 --RKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVL 422
++ + + +++ ++ QL + D + + K L+ G + + L
Sbjct: 757 LAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGL 816
Query: 423 AQKMLEEIRSRQPFFTQRELVDEEADEAYE-LLSQAESWQRLHNETRTLFPVVLEQLDDY 481
+K+ + Q + + EAD +Y+ L +S RL + F V E+
Sbjct: 817 VEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQV--EEAKRI 874
Query: 482 NAKLSDLQEALDQALN-YVRDAEDM-NRATAARQ--RDHEKQQERVREQMEVVNMSLSTS 537
K L + + ++ + R +++ N A+Q ++ + +E+ + + N++ S +
Sbjct: 875 KQKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRA 934
Query: 538 ADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDL 597
++L+ T E++ I+KN ++D K+E + + LS +S V +A D Q
Sbjct: 935 QEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQK-VSDASDKTQQA 993
Query: 598 QQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFAL 645
++ + + NG + +S + + I + EAN TA+ AL
Sbjct: 994 ERALGSAAADAQRA-KNGAGEALEISSEIEQEIGSLNLEANVTADGAL 1040
Score = 95.9 bits (237), Expect = 3e-19
Identities = 62/182 (34%), Positives = 82/182 (45%), Gaps = 36/182 (19%)
Query: 82 CDCNGNSNECL--------DGSGY-CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPC 132
CDCNG S +C+ G+G+ C++C NT G HCEKC +G+ R C PC
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR---CLPC 84
Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC-------- 184
C + R + + RC C G C+RC PG++ +L + C
Sbjct: 85 NC-----NSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH---MLTDAGCTQDQRLLD 136
Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNC 243
KCDC DP I CD G+C C TG +C+RC GYY D + C C C
Sbjct: 137 SKCDC----DPAGIAGPCD--AGRC-VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Query: 244 GG 245
G
Sbjct: 190 YG 191
Score = 73.9 bits (180), Expect = 1e-12
Identities = 49/140 (35%), Positives = 63/140 (45%), Gaps = 23/140 (16%)
Query: 65 EKCNAGFF-HTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
EKC GF+ H C+PC+CN G+ + D SG C C+ TG C++CL G+ +
Sbjct: 66 EKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRC-SCKPGVTGARCDRCLPGFHMLT 124
Query: 122 IRGAPQ----FCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY--- 174
G Q C C A A C A RC+C G C+RC GYY
Sbjct: 125 DAGCTQDQRLLDSKCDC---DPAGIAGPC----DAGRCVCKPAVTGERCDRCRSGYYNLD 177
Query: 175 -GNPLLIGSTCKKCDCSGNS 193
GNP C +C C G+S
Sbjct: 178 GGNP----EGCTQCFCYGHS 193
Score = 70.5 bits (171), Expect = 1e-11
Identities = 146/691 (21%), Positives = 244/691 (35%), Gaps = 142/691 (20%)
Query: 154 RCICNENYAGPNCERCAPGYYGNPLLIG--STCKKCDC--------------SGNSDPNL 197
+CIC Y G C+ CA GY + +G TC C+C SG+ +P++
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
Query: 198 IFEDC-------------------------------DEVTGQCRNCLRNTTGFKCERCAP 226
DC +EV C NC TG +CE CA
Sbjct: 441 ECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV--CNNCPPGVTGARCELCAD 498
Query: 227 GYYGDA----RIAKNCAVCNC-------GGGPCDSVTGECLEEGFEPPTGMDCPTIS--- 272
GY+GD + C C C G CD +TG CL + G+ C
Sbjct: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCL-KCIHNTAGIYCDQCKAGY 557
Query: 273 ---------CDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKT 323
DKC + + + + V G H Y
Sbjct: 558 FGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAFSCPACY---- 613
Query: 324 KLSERENQYALRKIQINNAENTMKSLLSDVE--ELVEKENQASRKGQLVQKESMDTINHA 381
NQ ++ Q M++L+S + + V + + + Q ++ D + A
Sbjct: 614 ------NQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDA 667
Query: 382 SQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRE 441
+ + ++ ++ ++ Y + + L + +R TQ +
Sbjct: 668 QISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQ 727
Query: 442 LVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDY---NAKLSDLQEALDQALNY 498
LS AES L N + D Y N S QEA A ++
Sbjct: 728 ------------LSLAESEASLGNTN-------IPASDHYVGPNGFKSLAQEATRLAESH 768
Query: 499 VRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRL------TLSELD 552
V A +M + T + ++ VR+ + S S S D L T S
Sbjct: 769 VESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQ 828
Query: 553 DIIKNASGIYAEIDGAKS-----ELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK 607
+ + A+ AEI+ +S L +S L +S Q ++ A+ ++Q+A+ LS
Sbjct: 829 QLTREAT--QAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQ--VEEAKRIKQKADSLSSL 884
Query: 608 L-HSSDMNGLVQKAL-----DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQ 661
+ D QK L +A + +N + ++++ A R +A+S +
Sbjct: 885 VTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALS-MGNA 943
Query: 662 IIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQA 721
Y E E++L RE + ++ EA A+ R S + ++SDA + Q
Sbjct: 944 TFY---EVESILKNLREFDLQVDNRKAEAEE--------AMKRLSYISQKVSDASDKTQQ 992
Query: 722 AER--GDAQQRLGQSRLITEEANRTTMEVQQ 750
AER G A +++ EA + E++Q
Sbjct: 993 AERALGSAAADAQRAKNGAGEALEISSEIEQ 1023
Score = 31.2 bits (69), Expect = 9.6
Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 7/65 (10%)
Query: 65 EKCNAGFFHTLSGE---CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
++C +G+++ G C C C G+S C + Y VH +T + +DG+
Sbjct: 167 DRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQD----VDGWKAVQ 222
Query: 122 IRGAP 126
G+P
Sbjct: 223 RNGSP 227
>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
Length = 639
Score = 132 bits (331), Expect = 4e-30
Identities = 66/185 (35%), Positives = 92/185 (49%), Gaps = 14/185 (7%)
Query: 57 LGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
+G + ++C G++ C+PC CN S C +G C++CQ N+ G HCE+C +G
Sbjct: 313 VGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEG 372
Query: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNE---NYAGPNCERCAPGY 173
+ A + C CPC SC K+ + C++ Y GPNC +C GY
Sbjct: 373 FYQSP--DATKECLRCPCSA---VTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGY 427
Query: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR 233
Y S C+KC C G+ DP + C +G+C NCL NTTGF CE C GY D
Sbjct: 428 YN----FDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHD-- 481
Query: 234 IAKNC 238
+ NC
Sbjct: 482 LEGNC 486
Score = 100 bits (250), Expect = 1e-20
Identities = 66/203 (32%), Positives = 86/203 (42%), Gaps = 28/203 (13%)
Query: 82 CDCNG----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
C+C+ N N C +G C C+ G HCE C +G+ + G CQPC C P
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSG---LCQPCDCS-P 295
Query: 138 HLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNL 197
H A + C N + +C C G C+RC GYYG + C C C+ S
Sbjct: 296 HGA-LSIPC---NSSGKCQCKVGVIGSICDRCQDGYYG---FSKNGCLPCQCNNRS---- 344
Query: 198 IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG----GPCDSVTG 253
CD +TG C NC N+ G CE C G+Y K C C C G C +
Sbjct: 345 --ASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSS 402
Query: 254 ECLEEGFEPPTGMDCPTISCDKC 276
E E + G P +C+KC
Sbjct: 403 ELEPECDQCKDGYIGP--NCNKC 423
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 128 bits (321), Expect = 6e-29
Identities = 82/264 (31%), Positives = 117/264 (44%), Gaps = 30/264 (11%)
Query: 15 LLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHT 74
L+ ++ + A + D+ G+ E + G P+ + C+ G+ T
Sbjct: 1088 LIRASYAQQPAESRVSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRT 1147
Query: 75 LSG----ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQ 130
SG C C C+G+S C +G C CQ +T G CE+C GY GD+ RG PQ CQ
Sbjct: 1148 PSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQ 1207
Query: 131 PCPC-PLPHLANFAESCY-RKNGAVRC-ICNENYAGPNCERCAPGYYGNPLLIGSTCKK- 186
CPC P A +C+ +G C C+ ++G +CERCAPGYYGNP G C++
Sbjct: 1208 LCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQ-GQPCQRD 1266
Query: 187 --------CDCSGNSDP-NLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAK 236
C+C DP + CD GQC+ C G C C P ++ A
Sbjct: 1267 SQVPGPIGCNC----DPQGSVSSQCD-AAGQCQ-CKAQVEGLTCSHCRPHHFHLSASNPD 1320
Query: 237 NCAVCNCGGGPCDSVTGECLEEGF 260
C C C G +T +C +
Sbjct: 1321 GCLPCFCMG-----ITQQCASSAY 1339
Score = 125 bits (314), Expect = 4e-28
Identities = 74/230 (32%), Positives = 105/230 (45%), Gaps = 23/230 (10%)
Query: 29 DNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSGE----CVPCDC 84
D A + +++ GR E E R +G + E C+A F G C C+C
Sbjct: 709 DIAMDTTVTHATSHGRAHSVE--ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNC 766
Query: 85 NGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP-LPHLANFA 143
NG+++ C G+C++CQ NT G C KC G+ GD+++ C+PCPCP + F+
Sbjct: 767 NGHASSCDPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFS 826
Query: 144 ESCY-RKNGAVRC-ICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFED 201
++C+ +G C C Y G CE CAPGY GNP+ G C+ N
Sbjct: 827 DTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPV--------NQEIVR 878
Query: 202 CDE-----VTGQCRNCLRNTTGFKCERCAPG-YYGDARIAKNCAVCNCGG 245
CDE +G+ C N G C CA G ++ R C C C G
Sbjct: 879 CDERGSMGTSGEACRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCMG 928
Score = 117 bits (292), Expect = 1e-25
Identities = 59/143 (41%), Positives = 74/143 (51%), Gaps = 7/143 (4%)
Query: 49 ETSEPRVALGRLPPAAEKCNAGFFHTLSG----ECVPCDCNGNSNECLDGSGYCVHCQRN 104
E E R G + + + C G+ T SG C C+CNG+S+ C +G C CQ N
Sbjct: 1526 EVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHN 1585
Query: 105 TTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLAN-FAESCYRKN-GAVRC-ICNENY 161
GE CE C GY GD+ G P+ CQPC CPL + N F+ +C G RC C Y
Sbjct: 1586 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGY 1645
Query: 162 AGPNCERCAPGYYGNPLLIGSTC 184
G CE+C PGY GNP + G C
Sbjct: 1646 TGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 78.2 bits (191), Expect = 7e-14
Identities = 40/93 (43%), Positives = 50/93 (53%), Gaps = 11/93 (11%)
Query: 155 CICNENYAGPNCERCAPGYY--GNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNC 212
C C Y G +C+ CAPGY G+ L +G C+ C+C+G+SD C TG C C
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGH-CELCECNGHSDL------CHPETGACSQC 1582
Query: 213 LRNTTGFKCERCAPGYYGDARIA--KNCAVCNC 243
N G CE CAPGYYGDA ++C C C
Sbjct: 1583 QHNAAGEFCELCAPGYYGDATAGTPEDCQPCAC 1615
Score = 70.1 bits (170), Expect = 2e-11
Identities = 41/138 (29%), Positives = 57/138 (41%), Gaps = 10/138 (7%)
Query: 101 CQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNEN 160
C G C+ C GY C+ C C ++ C+ + GA C N
Sbjct: 1532 CPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN-----GHSDLCHPETGACSQ-CQHN 1585
Query: 161 YAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDCDEVTG---QCRNCLRNT 216
AG CE CAPGYYG+ C+ C C + N+ C+ + +C C
Sbjct: 1586 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGY 1645
Query: 217 TGFKCERCAPGYYGDARI 234
TG CE+C PGY G+ +
Sbjct: 1646 TGQYCEQCGPGYVGNPSV 1663
Score = 66.2 bits (160), Expect = 3e-10
Identities = 36/135 (26%), Positives = 68/135 (50%), Gaps = 7/135 (5%)
Query: 1497 IRLRTRSSHGMIFYVSDQ-----EENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDG 1551
+ +RT ++ G++ + + + DF++L L G LV+ + +G + ++ S++ NDG
Sbjct: 4232 LEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEARLVSEDPINDG 4291
Query: 1552 LWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSI 1611
WH V +RE G + +DG ++ P KG +Y+GG + + +S
Sbjct: 4292 EWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSS- 4350
Query: 1612 YSFSGCLSNLQLNGA 1626
+GC+ NL L+ A
Sbjct: 4351 -GITGCVKNLVLHSA 4364
Score = 54.3 bits (129), Expect = 1e-06
Identities = 39/149 (26%), Positives = 60/149 (40%), Gaps = 10/149 (6%)
Query: 1518 DFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEE 1577
DF++L + G L + + +G +RS E G WH V R G L ++G R +
Sbjct: 3978 DFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGRWHRVSAERLNKDGSLRVNGGRPVLR 4037
Query: 1578 SLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASI--------- 1628
S P + +YLGGV P + + N F GC+ + +NG +
Sbjct: 4038 SSPGKSQGLNLHTLLYLGGVEPSVPL-SPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGS 4096
Query: 1629 TSASQTFSVTPCFEGPMETGTYFSTEGGY 1657
Q + +PC P + G G Y
Sbjct: 4097 QGIGQCYDSSPCERQPCQHGATCMPAGEY 4125
Score = 53.5 bits (127), Expect = 2e-06
Identities = 40/169 (23%), Positives = 79/169 (46%), Gaps = 16/169 (9%)
Query: 1642 EGPMETGTYFSTEGGYVVLDESFNIGLKF---EIAFEVRPRSSSGTLVH-----GHSVNG 1693
+ P + G YF +G F+ L I EVR ++SG L+ G + G
Sbjct: 4197 DAPGQYGAYFHDDGFLAFPGHVFSRSLPEVPETIELEVRTSTASGLLLWQGVEVGEAGQG 4256
Query: 1694 -EYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVN 1752
+++++ +++G ++ + G + + + + DG WHR+T +R+ + VD E
Sbjct: 4257 KDFISLGLQDGHLVFRYQLGSGE--ARLVSEDPINDGEWHRVTALREGRRGSIQVDGE-- 4312
Query: 1753 HVVGPLNPKP---IDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVI 1798
+V +P P ++ + V++GG P+ S TGC+++ V+
Sbjct: 4313 ELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNLVL 4361
Score = 44.7 bits (104), Expect = 8e-04
Identities = 35/148 (23%), Positives = 59/148 (39%), Gaps = 13/148 (8%)
Query: 1492 KSQFSIRLRTRSSHGMIFYVSDQE-----------ENDFMTLFLAHGRLVYMFNVGHKKL 1540
K + I R S+ GM+ Y + + DF++ L GR + F+ G
Sbjct: 3685 KFEIKITFRPDSADGMLLYNGQKRVPGSPTNLANRQPDFISFGLVGGRPEFRFDAGSGMA 3744
Query: 1541 KIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPG 1600
IR G +H V +R + G L++ L + + + +YLGG
Sbjct: 3745 TIRHPTPLALGHFHTVTLLRSLTQGSLIVGDLAPVNGTSQGKFQGLDLNEELYLGGYPDY 3804
Query: 1601 KAVKNVQINSIYSFSGCLSNLQLNGASI 1628
A+ ++S F GC+ L++ G I
Sbjct: 3805 GAIPKAGLSS--GFIGCVRELRIQGEEI 3830
Score = 43.1 bits (100), Expect = 0.002
Identities = 42/174 (24%), Positives = 70/174 (40%), Gaps = 33/174 (18%)
Query: 1669 KFEIAFEVRPRSSSGTLVH-------GHSVN-----GEYLNVHMKNGQVIVKVNNGIRDF 1716
KFEI RP S+ G L++ G N ++++ + G+ + + G
Sbjct: 3685 KFEIKITFRPDSADGMLLYNGQKRVPGSPTNLANRQPDFISFGLVGGRPEFRFDAG--SG 3742
Query: 1717 STSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNP---------KPIDHRE 1767
++ L G +H +T++R L +VG L P + +D E
Sbjct: 3743 MATIRHPTPLALGHFHTVTLLRSLTQGSL--------IVGDLAPVNGTSQGKFQGLDLNE 3794
Query: 1768 PVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSCP 1821
+++GG P+ P+ S F GC+R I G + F L A I+ CP
Sbjct: 3795 ELYLGGYPDYGAIPKAGLSSGFIGCVRELRIQGEEIVFHDLNLT--AHGISHCP 3846
Score = 41.6 bits (96), Expect = 0.007
Identities = 44/190 (23%), Positives = 77/190 (40%), Gaps = 17/190 (8%)
Query: 1640 CFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNG---EYL 1696
C EG T S G Y+ L N + + E +P + G L+ +G +++
Sbjct: 3921 CEEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLAPDGVLLFSGGKSGPVEDFV 3980
Query: 1697 NVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVG 1756
++ M G + + G + + L GRWHR++ R + D VN
Sbjct: 3981 SLAMVGGHLEFRYELG--SGLAVLRSAEPLALGRWHRVSAER----LNKDGSLRVNGGRP 4034
Query: 1757 PLNPKP-----IDHREPVFVGGVPESL-LTPRLAPSKPFTGCIRHFVIDGHPVSFSKAAL 1810
L P ++ +++GGV S+ L+P S F GC+ ++G + + + L
Sbjct: 4035 VLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFL 4094
Query: 1811 VSGAVSINSC 1820
G+ I C
Sbjct: 4095 --GSQGIGQC 4102
Score = 32.7 bits (73), Expect = 3.3
Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 28/96 (29%)
Query: 208 QCRNCLRNTTGFKCERC------APG--YYGDARIAKNCAVCNCGG--GPCDSVTGECL- 256
+CR C +G CE C PG Y G C+ CNC G CD V G CL
Sbjct: 730 ECR-CPIGYSGLSCESCDAHFTRVPGGPYLG------TCSGCNCNGHASSCDPVYGHCLN 782
Query: 257 -EEGFEPPTGMDCPTISCDKC-VWDLTDALRLAALS 290
+ E P C+KC DA++ A S
Sbjct: 783 CQHNTEGP--------QCNKCKAGFFGDAMKATATS 810
Score = 31.6 bits (70), Expect = 7.4
Identities = 41/188 (21%), Positives = 70/188 (37%), Gaps = 21/188 (11%)
Query: 841 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK 900
+ V ++T L T Y K +K ++AD +LY G K LA +
Sbjct: 3660 ERVVPYFTQTPYSFLPLPTIKDAYRKFEIKITFRPDSADGMLLYNGQKRVPGSPTNLANR 3719
Query: 901 NDNLVYVYNLGTKDVEIPLDS--------KPVSSWPAYFSIVKIERVGKHGKVFLTVPSL 952
+ + +G + E D+ P +F V + R G + +
Sbjct: 3720 QPDFISFGLVGGRP-EFRFDAGSGMATIRHPTPLALGHFHTVTLLRSLTQGSLIV----- 3773
Query: 953 SSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLN 1012
A +G+F G LDL+ E Y+GG P +P + GF+GC+ +
Sbjct: 3774 GDLAPVNGTSQGKFQG----LDLNEE---LYLGGYPDYGAIPKAGLSSGFIGCVRELRIQ 3826
Query: 1013 NDVISLYN 1020
+ I ++
Sbjct: 3827 GEEIVFHD 3834
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 106 bits (265), Expect = 2e-22
Identities = 85/357 (23%), Positives = 168/357 (47%), Gaps = 40/357 (11%)
Query: 1490 GAKSQFSIRLRTRSSHGMI-FYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQ--- 1545
G K+ F RT+ G+I F S + ++ L L GRL ++F+ +++ +
Sbjct: 1543 GIKASF----RTKVPEGLIVFAASPGNQEEYFALQLKKGRLYFLFDPQGSPVEVTTTNDH 1598
Query: 1546 -EKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVK 1604
++Y+DG WH++I IR ++ G++ +DG+ ++ ++LGG+ +
Sbjct: 1599 GKQYSDGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVIGDNTGVFLGGLPRSYTIL 1658
Query: 1605 NVQINSIY-SFSGCLSNLQL----NGASI------TSASQTFSVTPCFEG---PMETGTY 1650
I F GCL ++ N ++I S+ + +V +EG + G
Sbjct: 1659 RKDPEIIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQINVYNSWEGCPASLNEGAQ 1718
Query: 1651 FSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNG-EYLNVHMKNGQVIVKV 1709
F G + F+ G+ FEI+F+ R +G L+ ++ +G ++L + +K+G + ++
Sbjct: 1719 FLGAGFLELHPYMFHGGMNFEISFKFRTDQLNGLLLFVYNKDGPDFLAMELKSGILTFRL 1778
Query: 1710 NNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPV 1769
N + + S C+G+W+++ + ++ + + V+ + H +P+ PV
Sbjct: 1779 NTSLAFTQVDLLLGLSYCNGKWNKVIIKKEGSFISASVNGLMKH-ASESGDQPLVVNSPV 1837
Query: 1770 FVGGVPESLLT--PRLAPSKPFTGCIRHFVIDGHPVSFSKAALV------SGAVSIN 1818
+VGG+P+ LL L + F GC++ V F++ A+V SGAV +N
Sbjct: 1838 YVGGIPQELLNSYQHLCLEQGFGGCMK-------DVKFTRGAVVNLASVSSGAVRVN 1887
Score = 92.4 bits (228), Expect = 4e-18
Identities = 62/220 (28%), Positives = 90/220 (40%), Gaps = 40/220 (18%)
Query: 79 CVPCDCNGNSNEC--------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGD--SI 122
C PC CN +S C G G C C+ NTTG +CE C D + +
Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631
Query: 123 RGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGS 182
A C+PC C N + C + G +C C + +G C +C G+Y L
Sbjct: 632 PSAIDVCKPCDCDTVGTRNGSILCDQIGG--QCNCKRHVSGRQCNQCQNGFYNLQELDPD 689
Query: 183 TCKKCDC--SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGY-----YGDARIA 235
C C+C SG D ++ C + +GQC+ C N G +C+ C G+ + D
Sbjct: 690 GCSPCNCNTSGTVDGDI---TCHQNSGQCK-CKANVIGLRCDHCNFGFKFLRSFNDV--- 742
Query: 236 KNCAVCNCG-----GGPCDSVTGECLEEGFEPPTGMDCPT 270
C C C C+ +G+C E + G+ C T
Sbjct: 743 -GCEPCQCNLHGSVNKFCNPHSGQC--ECKKEAKGLQCDT 779
Score = 85.9 bits (211), Expect = 3e-16
Identities = 63/216 (29%), Positives = 94/216 (43%), Gaps = 47/216 (21%)
Query: 74 TLSGECVPCDCNGNSNEC-LDGSGYCVHCQRN--TTGEHCEKCLDGYIGDSIRGAPQF-- 128
T+SG C C+G+++ C Y C + T G HC++CL Y R Q
Sbjct: 513 TISGRC---QCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569
Query: 129 --CQPCPCPLPHLANFAESC-------------YRKNGAVRCICNENYAGPNCERCAPGY 173
C+PC C + ++SC +R G V C N G NCE C +
Sbjct: 570 FNCKPCQC-----NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYF 624
Query: 174 Y----GNPLLIGSTCKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG 227
+ +P I CK CDC G + +++ CD++ GQC NC R+ +G +C +C G
Sbjct: 625 FRQVGADPSAI-DVCKPCDCDTVGTRNGSIL---CDQIGGQC-NCKRHVSGRQCNQCQNG 679
Query: 228 YYGDARI-AKNCAVCNC-------GGGPCDSVTGEC 255
+Y + C+ CNC G C +G+C
Sbjct: 680 FYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQC 715
Score = 85.9 bits (211), Expect = 3e-16
Identities = 63/211 (29%), Positives = 91/211 (43%), Gaps = 35/211 (16%)
Query: 65 EKCNAGFFHTLSGE---CVPCDCN--GNSNE-CLDGSGYCVHCQRNTTGEHCEKCLDGYI 118
+ CN GF S C PC CN G+ N+ C SG C C++ G C+ C + +
Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAKGLQCDTCRENFY 785
Query: 119 GDSIRGAPQFCQPCPC----PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
G + C+ C C LP C K G +CIC N G C +C G +
Sbjct: 786 GLDVTN----CKACDCDTAGSLP-----GTVCNAKTG--QCICKPNVEGRQCNKCLEGNF 834
Query: 175 GNPLLIGSTCKKCDC--SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-D 231
C C+C +G + +L+ C++ TGQC C TG +C +C P Y
Sbjct: 835 YLRQNNSFLCLPCNCDKTGTINGSLL---CNKSTGQC-PCKLGVTGLRCNQCEPHRYNLT 890
Query: 232 ARIAKNCAVCNCG------GGPCDSVTGECL 256
++C +C C G CD ++G+CL
Sbjct: 891 IDNFQHCQMCECDSLGTLPGTICDPISGQCL 921
Score = 81.3 bits (199), Expect = 8e-15
Identities = 68/229 (29%), Positives = 92/229 (40%), Gaps = 37/229 (16%)
Query: 66 KCNAGFFHTLSGE---CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117
KC G F+ C+PC+C+ S C +G C C+ TG C +C
Sbjct: 828 KCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCP-CKLGVTGLRCNQCEPHR 886
Query: 118 IGDSIRGAPQFCQPCPCP----LPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGY 173
+I Q CQ C C LP C +G +C+C N G C +C PG+
Sbjct: 887 YNLTIDNF-QHCQMCECDSLGTLP-----GTICDPISG--QCLCVPNRQGRRCNQCQPGF 938
Query: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR 233
Y +P + C C C N I C+ +TGQC + G +C++C Y+G
Sbjct: 939 YISPGN-ATGCLPCSCHTTGAVNHI---CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDP 994
Query: 234 IAKNCAVCNCG-----GGPCDSVTGECLEEGFEPPTGMDCPTISCDKCV 277
C CNC C VTG+C + F TG CD CV
Sbjct: 995 QTGRCQPCNCHLSGALNETCHLVTGQCFCKQF--VTGS-----KCDACV 1036
Score = 66.6 bits (161), Expect = 2e-10
Identities = 48/153 (31%), Positives = 65/153 (42%), Gaps = 17/153 (11%)
Query: 79 CVPCDCNG----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPC 134
C C+C+ C SG C+ C N G C +C G+ G C PC C
Sbjct: 897 CQMCECDSLGTLPGTICDPISGQCL-CVPNRQGRRCNQCQPGFYISP--GNATGCLPCSC 953
Query: 135 PLPHLANFAESCYRKNGAVRCICNE-NYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNS 193
N C G +C+C + + AG C++C Y+G G C+ C+C +
Sbjct: 954 HTTGAVNHI--CNSLTG--QCVCQDASIAGQRCDQCKDHYFGFDPQTGR-CQPCNCHLSG 1008
Query: 194 DPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226
N E C VTGQC C + TG KC+ C P
Sbjct: 1009 ALN---ETCHLVTGQCF-CKQFVTGSKCDACVP 1037
Score = 59.7 bits (143), Expect = 3e-08
Identities = 35/112 (31%), Positives = 52/112 (46%), Gaps = 13/112 (11%)
Query: 66 KCNAGFFHTLSGE--CVPCDCNGN---SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG- 119
+C GF+ + C+PC C+ ++ C +G CV + G+ C++C D Y G
Sbjct: 933 QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992
Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAP 171
D G CQPC C L N E+C+ G +C C + G C+ C P
Sbjct: 993 DPQTGR---CQPCNCHLSGALN--ETCHLVTG--QCFCKQFVTGSKCDACVP 1037
Score = 56.2 bits (134), Expect = 3e-07
Identities = 74/269 (27%), Positives = 103/269 (38%), Gaps = 49/269 (18%)
Query: 1052 FDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMV---NGSMFFRLEMRNGYLH 1108
F G+GY T T RT GLI+ N +F L+++ G L+
Sbjct: 1522 FIGNGYCKFPSSTHPVNT-DFTGIKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLY 1580
Query: 1109 VFYDFGFSGGPVHLEDTLKKA-QINDAKYHEISIIYHNDKKMILVVDRRHVKS---MDNE 1164
+D G PV + T Q +D K+HEI I H I +D + S ++
Sbjct: 1581 FLFDP--QGSPVEVTTTNDHGKQYSDGKWHEIIAIRHQAFGQI-TLDGIYTGSSAILNGS 1637
Query: 1165 KMKIPFTDIYIGGAP---------PEILQSRALRAHLPLDINFRGCMKGFQFQKK----- 1210
+ T +++GG P PEI+Q F GC+K F K
Sbjct: 1638 TVIGDNTGVFLGGLPRSYTILRKDPEIIQK-----------GFVGCLKDVHFMKNYNPSA 1686
Query: 1211 -----DFNLLE-QTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDG--FEGGFN 1262
D+ E Q GCP ++ A F G F+ + F G FE F
Sbjct: 1687 IWEPLDWQSSEEQINVYNSWEGCPAS--LNEGAQFLGAGFL-ELHPYMFHGGMNFEISFK 1743
Query: 1263 FRTLQPNGLLF--YYASGSDVFSISLDNG 1289
FRT Q NGLL Y G D ++ L +G
Sbjct: 1744 FRTDQLNGLLLFVYNKDGPDFLAMELKSG 1772
Score = 51.6 bits (122), Expect = 7e-06
Identities = 70/356 (19%), Positives = 144/356 (40%), Gaps = 44/356 (12%)
Query: 869 VKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWP 928
+K T+ + I++ S ++EY L +K L ++++
Sbjct: 1544 IKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLYFLFD------------------- 1584
Query: 929 AYFSIVKIERVGKHGKVFL-----TVPSLSSTAEEKFIKKGEFSGDDSLLD---LDPEDT 980
S V++ HGK + + ++ A + G ++G ++L+ + ++T
Sbjct: 1585 PQGSPVEVTTTNDHGKQYSDGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVIGDNT 1644
Query: 981 VFYVGGVPSNFKL---PTSLNLPGFVGCLELATL--NNDVISLYNFKHIYNMDPSTSVPC 1035
++GG+P ++ + + GFVGCL+ N + +++ + + +V
Sbjct: 1645 GVFLGGLPRSYTILRKDPEIIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQINVYN 1704
Query: 1036 ARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVN-- 1093
+ + + + A + G+G+ + G G + RT NGL+L + N
Sbjct: 1705 SWEGCPASLNEGAQFL--GAGFLELHPYMFHG--GMNFEISFKFRTDQLNGLLLFVYNKD 1760
Query: 1094 GSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVV 1153
G F +E+++G L + + V D L + K++++ I V
Sbjct: 1761 GPDFLAMELKSGILTFRLNTSLAFTQV---DLLLGLSYCNGKWNKVIIKKEGSFISASVN 1817
Query: 1154 DRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQK 1209
S ++ + + +Y+GG P E+L S HL L+ F GCMK +F +
Sbjct: 1818 GLMKHASESGDQPLVVNSPVYVGGIPQELLNS---YQHLCLEQGFGGCMKDVKFTR 1870
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 103 bits (257), Expect = 2e-21
Identities = 180/837 (21%), Positives = 314/837 (37%), Gaps = 124/837 (14%)
Query: 78 ECVPCDCNGNSNEC---------LDGS--GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
EC CDCNG+S C G+ G C +C+ +T G++CE+C Y + GA
Sbjct: 312 ECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGAS 371
Query: 127 --QFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
+ C C C P A C G +C+C E+ G C+ C PG+ G C
Sbjct: 372 IQETCISCECD-PDGAVPGAPCDPVTG--QCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244
+CDC N + CDE +G+C CL N G KC++CAP Y+ + C C C
Sbjct: 429 HRCDC--NILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACD 484
Query: 245 -----GGPCDSVTGEC-LEEGFEPPTGMDCPTISCDKC----VWDLTDALRLAALSIEEG 294
C+ TG+C EGF G+ C + +C D+ R
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGF---GGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGT 541
Query: 295 KSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVE 354
+ +SG R L + + + Y R ++ +D+
Sbjct: 542 EGPGCDKASGRCLCRP--------GLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLR 593
Query: 355 ELVEKENQASRKGQLVQKESMDTINHASQ---LVEQAHDMRDKIQEINNKMLYYGEEHEL 411
E QA R G+L + + L + D + KI++I +L E
Sbjct: 594 E------QALRFGRLRNATASLWSGPGLEDRGLASRILDAKSKIEQI-RAVLSSPAVTEQ 646
Query: 412 SPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLF 471
+++ ++ ++ L+ ++ P +E L ES R N T++
Sbjct: 647 EVAQVASAILSLRRTLQGLQLDLPL----------EEETLSLPRDLESLDRSFNGLLTMY 696
Query: 472 PVVLEQLD-----DYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQ 526
EQ + D + L A +Q+ + D +R + RD ++ ER+ Q
Sbjct: 697 QRKREQFEKISSADPSGAFRMLSTAYEQSAQAAQQVSDSSR-LLDQLRDSRREAERLVRQ 755
Query: 527 MEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDL 586
T + L RL +S L D L + L S +
Sbjct: 756 ---AGGGGGTGSPKLVALRLEMSSLPD------------------LTPTFNKLCGNSRQM 794
Query: 587 VQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKA----LDASNVYENIVNYVSEANETAE 642
I +L + N + S G++ +A L A V E + + ++ T +
Sbjct: 795 ACTPISCPGELCPQDNGTA---CGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQ 851
Query: 643 F---ALNTTDRIYDAVSGIDTQIIYHKDESENLLNQAREL--QAKAESSSDEAVADTSRR 697
A + +I + ++TQ+ + + E + + R L Q + + + A T +
Sbjct: 852 MIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQE 911
Query: 698 VGGA-----LARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQAT 752
V A L SA + + ++ + AA + L Q++ A R E ++A
Sbjct: 912 VSEAVLALWLPTDSATVLQKMNEIQAI-AARLPNVDLVLSQTKQDIARARRLQAEAEEAR 970
Query: 753 A---PMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQ-KRPA 808
+ + + + NL+ A+ A+D ++ + + + D++ V+Q RPA
Sbjct: 971 SRAHAVEGQVEDVVGNLRQ-----GTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPA 1025
Query: 809 SNVSASI--------QRIRELIAQTRSV-ASKIQVSMMFDGQSAVEVHSRTSMDDLK 856
+ S+ R+ EL Q R A +Q + +G S + ++ + +K
Sbjct: 1026 EKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIK 1082
Score = 89.0 bits (219), Expect = 4e-17
Identities = 47/122 (38%), Positives = 59/122 (48%), Gaps = 20/122 (16%)
Query: 155 CICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNLIFEDCDE 204
C+C N AGPNCERCAP Y P C++CDC+G+S DP +
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 205 VTGQCRNCLRNTTGFKCERCAPGYYGDAR----IAKNCAVCNCG------GGPCDSVTGE 254
G C NC +T G CERC Y+ + R I + C C C G PCD VTG+
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398
Query: 255 CL 256
C+
Sbjct: 399 CV 400
Score = 82.8 bits (203), Expect = 3e-15
Identities = 64/212 (30%), Positives = 86/212 (40%), Gaps = 46/212 (21%)
Query: 82 CDCNGNSNECLDGSG-------------YCVHCQRNTTGEHCEKCLDGYIGDSIRGA--- 125
C C+G+++ C G CV CQ NT G +CE+C Y R A
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 126 -PQFCQPCPCPLPHLANFAESCY----------RKNGAVRCICNENYAGPNCERCAPGYY 174
CQ C C +E+C+ G V C ++ G NCERC Y+
Sbjct: 309 DAHECQRCDC-----NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363
Query: 175 GN---PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG- 230
N I TC C+C + D + CD VTGQC C + G +C+ C PG+ G
Sbjct: 364 RNRRPGASIQETCISCEC--DPDGAVPGAPCDPVTGQC-VCKEHVQGERCDLCKPGFTGL 420
Query: 231 DARIAKNCAVCNCG------GGPCDSVTGECL 256
+ C C+C PCD +G CL
Sbjct: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCL 452
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 18/121 (14%)
Query: 62 PAAEKCNAGFFHTLSGE-CVPCDC---NGNSNECLDGSGYCVHCQRNTTGEHCE-----K 112
P ++C + SG+ C PC C N S +C +G C C+ G C +
Sbjct: 460 PKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCP-CREGFGGLMCSAAAIRQ 518
Query: 113 CLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172
C D GD G C+ C C C + +G RC+C GP C++C G
Sbjct: 519 CPDRTYGDVATG----CRACDCDFR--GTEGPGCDKASG--RCLCRPGLTGPRCDQCQRG 570
Query: 173 Y 173
Y
Sbjct: 571 Y 571
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 103 bits (257), Expect = 2e-21
Identities = 180/837 (21%), Positives = 314/837 (37%), Gaps = 124/837 (14%)
Query: 78 ECVPCDCNGNSNEC---------LDGS--GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
EC CDCNG+S C G+ G C +C+ +T G++CE+C Y + GA
Sbjct: 312 ECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGAS 371
Query: 127 --QFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
+ C C C P A C G +C+C E+ G C+ C PG+ G C
Sbjct: 372 IQETCISCECD-PDGAVPGAPCDPVTG--QCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244
+CDC N + CDE +G+C CL N G KC++CAP Y+ + C C C
Sbjct: 429 HRCDC--NILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACD 484
Query: 245 -----GGPCDSVTGEC-LEEGFEPPTGMDCPTISCDKC----VWDLTDALRLAALSIEEG 294
C+ TG+C EGF G+ C + +C D+ R
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGF---GGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGT 541
Query: 295 KSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVE 354
+ +SG R L + + + Y R ++ +D+
Sbjct: 542 EGPGCDKASGRCLCRP--------GLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLR 593
Query: 355 ELVEKENQASRKGQLVQKESMDTINHASQ---LVEQAHDMRDKIQEINNKMLYYGEEHEL 411
E QA R G+L + + L + D + KI++I +L E
Sbjct: 594 E------QALRFGRLRNATASLWSGPGLEDRGLASRILDAKSKIEQI-RAVLSSPAVTEQ 646
Query: 412 SPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLF 471
+++ ++ ++ L+ ++ P +E L ES R N T++
Sbjct: 647 EVAQVASAILSLRRTLQGLQLDLPL----------EEETLSLPRDLESLDRSFNGLLTMY 696
Query: 472 PVVLEQLD-----DYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQ 526
EQ + D + L A +Q+ + D +R + RD ++ ER+ Q
Sbjct: 697 QRKREQFEKISSADPSGAFRMLSTAYEQSAQAAQQVSDSSR-LLDQLRDSRREAERLVRQ 755
Query: 527 MEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDL 586
T + L RL +S L D L + L S +
Sbjct: 756 ---AGGGGGTGSPKLVALRLEMSSLPD------------------LTPTFNKLCGNSRQM 794
Query: 587 VQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKA----LDASNVYENIVNYVSEANETAE 642
I +L + N + S G++ +A L A V E + + ++ T +
Sbjct: 795 ACTPISCPGELCPQDNGTA---CGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQ 851
Query: 643 F---ALNTTDRIYDAVSGIDTQIIYHKDESENLLNQAREL--QAKAESSSDEAVADTSRR 697
A + +I + ++TQ+ + + E + + R L Q + + + A T +
Sbjct: 852 MIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQE 911
Query: 698 VGGA-----LARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQAT 752
V A L SA + + ++ + AA + L Q++ A R E ++A
Sbjct: 912 VSEAVLALWLPTDSATVLQKMNEIQAI-AARLPNVDLVLSQTKQDIARARRLQAEAEEAR 970
Query: 753 A---PMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQ-KRPA 808
+ + + + NL+ A+ A+D ++ + + + D++ V+Q RPA
Sbjct: 971 SRAHAVEGQVEDVVGNLRQ-----GTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPA 1025
Query: 809 SNVSASI--------QRIRELIAQTRSV-ASKIQVSMMFDGQSAVEVHSRTSMDDLK 856
+ S+ R+ EL Q R A +Q + +G S + ++ + +K
Sbjct: 1026 EKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIK 1082
Score = 89.0 bits (219), Expect = 4e-17
Identities = 47/122 (38%), Positives = 59/122 (48%), Gaps = 20/122 (16%)
Query: 155 CICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNLIFEDCDE 204
C+C N AGPNCERCAP Y P C++CDC+G+S DP +
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 205 VTGQCRNCLRNTTGFKCERCAPGYYGDAR----IAKNCAVCNCG------GGPCDSVTGE 254
G C NC +T G CERC Y+ + R I + C C C G PCD VTG+
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398
Query: 255 CL 256
C+
Sbjct: 399 CV 400
Score = 82.8 bits (203), Expect = 3e-15
Identities = 64/212 (30%), Positives = 86/212 (40%), Gaps = 46/212 (21%)
Query: 82 CDCNGNSNECLDGSG-------------YCVHCQRNTTGEHCEKCLDGYIGDSIRGA--- 125
C C+G+++ C G CV CQ NT G +CE+C Y R A
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 126 -PQFCQPCPCPLPHLANFAESCY----------RKNGAVRCICNENYAGPNCERCAPGYY 174
CQ C C +E+C+ G V C ++ G NCERC Y+
Sbjct: 309 DAHECQRCDC-----NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363
Query: 175 GN---PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG- 230
N I TC C+C + D + CD VTGQC C + G +C+ C PG+ G
Sbjct: 364 RNRRPGASIQETCISCEC--DPDGAVPGAPCDPVTGQC-VCKEHVQGERCDLCKPGFTGL 420
Query: 231 DARIAKNCAVCNCG------GGPCDSVTGECL 256
+ C C+C PCD +G CL
Sbjct: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCL 452
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 18/121 (14%)
Query: 62 PAAEKCNAGFFHTLSGE-CVPCDC---NGNSNECLDGSGYCVHCQRNTTGEHCE-----K 112
P ++C + SG+ C PC C N S +C +G C C+ G C +
Sbjct: 460 PKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCP-CREGFGGLMCSAAAIRQ 518
Query: 113 CLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172
C D GD G C+ C C C + +G RC+C GP C++C G
Sbjct: 519 CPDRTYGDVATG----CRACDCDFR--GTEGPGCDKASG--RCLCRPGLTGPRCDQCQRG 570
Query: 173 Y 173
Y
Sbjct: 571 Y 571
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 103 bits (257), Expect = 2e-21
Identities = 180/837 (21%), Positives = 314/837 (37%), Gaps = 124/837 (14%)
Query: 78 ECVPCDCNGNSNEC---------LDGS--GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
EC CDCNG+S C G+ G C +C+ +T G++CE+C Y + GA
Sbjct: 312 ECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGAS 371
Query: 127 --QFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
+ C C C P A C G +C+C E+ G C+ C PG+ G C
Sbjct: 372 IQETCISCECD-PDGAVPGAPCDPVTG--QCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244
+CDC N + CDE +G+C CL N G KC++CAP Y+ + C C C
Sbjct: 429 HRCDC--NILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACD 484
Query: 245 -----GGPCDSVTGEC-LEEGFEPPTGMDCPTISCDKC----VWDLTDALRLAALSIEEG 294
C+ TG+C EGF G+ C + +C D+ R
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGF---GGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGT 541
Query: 295 KSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVE 354
+ +SG R L + + + Y R ++ +D+
Sbjct: 542 EGPGCDKASGRCLCRP--------GLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLR 593
Query: 355 ELVEKENQASRKGQLVQKESMDTINHASQ---LVEQAHDMRDKIQEINNKMLYYGEEHEL 411
E QA R G+L + + L + D + KI++I +L E
Sbjct: 594 E------QALRFGRLRNATASLWSGPGLEDRGLASRILDAKSKIEQI-RAVLSSPAVTEQ 646
Query: 412 SPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLF 471
+++ ++ ++ L+ ++ P +E L ES R N T++
Sbjct: 647 EVAQVASAILSLRRTLQGLQLDLPL----------EEETLSLPRDLESLDRSFNGLLTMY 696
Query: 472 PVVLEQLD-----DYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQ 526
EQ + D + L A +Q+ + D +R + RD ++ ER+ Q
Sbjct: 697 QRKREQFEKISSADPSGAFRMLSTAYEQSAQAAQQVSDSSR-LLDQLRDSRREAERLVRQ 755
Query: 527 MEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDL 586
T + L RL +S L D L + L S +
Sbjct: 756 ---AGGGGGTGSPKLVALRLEMSSLPD------------------LTPTFNKLCGNSRQM 794
Query: 587 VQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKA----LDASNVYENIVNYVSEANETAE 642
I +L + N + S G++ +A L A V E + + ++ T +
Sbjct: 795 ACTPISCPGELCPQDNGTA---CGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQ 851
Query: 643 F---ALNTTDRIYDAVSGIDTQIIYHKDESENLLNQAREL--QAKAESSSDEAVADTSRR 697
A + +I + ++TQ+ + + E + + R L Q + + + A T +
Sbjct: 852 MIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQE 911
Query: 698 VGGA-----LARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQAT 752
V A L SA + + ++ + AA + L Q++ A R E ++A
Sbjct: 912 VSEAVLALWLPTDSATVLQKMNEIQAI-AARLPNVDLVLSQTKQDIARARRLQAEAEEAR 970
Query: 753 A---PMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQ-KRPA 808
+ + + + NL+ A+ A+D ++ + + + D++ V+Q RPA
Sbjct: 971 SRAHAVEGQVEDVVGNLRQ-----GTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPA 1025
Query: 809 SNVSASI--------QRIRELIAQTRSV-ASKIQVSMMFDGQSAVEVHSRTSMDDLK 856
+ S+ R+ EL Q R A +Q + +G S + ++ + +K
Sbjct: 1026 EKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIK 1082
Score = 89.0 bits (219), Expect = 4e-17
Identities = 47/122 (38%), Positives = 59/122 (48%), Gaps = 20/122 (16%)
Query: 155 CICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNLIFEDCDE 204
C+C N AGPNCERCAP Y P C++CDC+G+S DP +
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 205 VTGQCRNCLRNTTGFKCERCAPGYYGDAR----IAKNCAVCNCG------GGPCDSVTGE 254
G C NC +T G CERC Y+ + R I + C C C G PCD VTG+
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398
Query: 255 CL 256
C+
Sbjct: 399 CV 400
Score = 82.8 bits (203), Expect = 3e-15
Identities = 64/212 (30%), Positives = 86/212 (40%), Gaps = 46/212 (21%)
Query: 82 CDCNGNSNECLDGSG-------------YCVHCQRNTTGEHCEKCLDGYIGDSIRGA--- 125
C C+G+++ C G CV CQ NT G +CE+C Y R A
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 126 -PQFCQPCPCPLPHLANFAESCY----------RKNGAVRCICNENYAGPNCERCAPGYY 174
CQ C C +E+C+ G V C ++ G NCERC Y+
Sbjct: 309 DAHECQRCDC-----NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363
Query: 175 GN---PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG- 230
N I TC C+C + D + CD VTGQC C + G +C+ C PG+ G
Sbjct: 364 RNRRPGASIQETCISCEC--DPDGAVPGAPCDPVTGQC-VCKEHVQGERCDLCKPGFTGL 420
Query: 231 DARIAKNCAVCNCG------GGPCDSVTGECL 256
+ C C+C PCD +G CL
Sbjct: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCL 452
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 18/121 (14%)
Query: 62 PAAEKCNAGFFHTLSGE-CVPCDC---NGNSNECLDGSGYCVHCQRNTTGEHCE-----K 112
P ++C + SG+ C PC C N S +C +G C C+ G C +
Sbjct: 460 PKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCP-CREGFGGLMCSAAAIRQ 518
Query: 113 CLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172
C D GD G C+ C C C + +G RC+C GP C++C G
Sbjct: 519 CPDRTYGDVATG----CRACDCDFR--GTEGPGCDKASG--RCLCRPGLTGPRCDQCQRG 570
Query: 173 Y 173
Y
Sbjct: 571 Y 571
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 100 bits (249), Expect = 1e-20
Identities = 72/249 (28%), Positives = 102/249 (40%), Gaps = 40/249 (16%)
Query: 82 CDCNGNSNECLD----------GSGYCVH----CQRNTTGEHCEKCLDGY------IGDS 121
C CNG++++C+ G+ + VH C+ NT G HC+ C Y D
Sbjct: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADG 321
Query: 122 IRGAPQFCQPCPC----PLPHL-ANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176
GAP C+ C C H N E+ ++G V C N G C+RC PG+Y +
Sbjct: 322 KTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRD 381
Query: 177 ---PLLIGSTCKKCDCSGNSD---PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG 230
P CK C C P CD G C C G +C+RC GY+G
Sbjct: 382 LRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC-PCKPGVAGRRCDRCMVGYWG 440
Query: 231 DARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGMDCPTI----SCDKCVWDLTDALRL 286
C C+C G CD +TG+C+ + + P + + W+ DA
Sbjct: 441 FGDY--GCRPCDCAGS-CDPITGDCISSHTDIDWYHEVPDFRPVHNKSEPAWEWEDAQGF 497
Query: 287 AALSIEEGK 295
+AL + GK
Sbjct: 498 SAL-LHSGK 505
Score = 86.7 bits (213), Expect = 2e-16
Identities = 52/151 (34%), Positives = 67/151 (44%), Gaps = 35/151 (23%)
Query: 78 ECVPCDCNGNSNECL-----------DGSGYCVHCQRNTTGEHCEKCLDGYIGDSIR--G 124
EC C CNG+++ C G C CQ NT G++C++C G+ D R
Sbjct: 328 ECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFS 387
Query: 125 APQFCQPCPC------PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
AP C+PC C LP AN C NG C C AG C+RC GY+G
Sbjct: 388 APDACKPCSCHPVGSAVLP--ANSVTFCDPSNG--DCPCKPGVAGRRCDRCMVGYWG--- 440
Query: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQC 209
C+ CDC+G+ CD +TG C
Sbjct: 441 FGDYGCRPCDCAGS---------CDPITGDC 462
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 92.4 bits (228), Expect = 4e-18
Identities = 62/220 (28%), Positives = 90/220 (40%), Gaps = 40/220 (18%)
Query: 79 CVPCDCNGNSNEC--------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGD--SI 122
C PC CN +S C G G C C+ NTTG +CE C D + +
Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631
Query: 123 RGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGS 182
A C+PC C N + C + G +C C + +G C +C G+Y L
Sbjct: 632 PSAIDVCKPCDCDTVGTRNGSILCDQIGG--QCNCKRHVSGRQCNQCQNGFYNLQELDPD 689
Query: 183 TCKKCDC--SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGY-----YGDARIA 235
C C+C SG D ++ C + +GQC+ C N G +C+ C G+ + D
Sbjct: 690 GCSPCNCNTSGTVDGDI---TCHQNSGQCK-CKANVIGLRCDHCNFGFKFLRSFNDV--- 742
Query: 236 KNCAVCNCG-----GGPCDSVTGECLEEGFEPPTGMDCPT 270
C C C C+ +G+C E + G+ C T
Sbjct: 743 -GCEPCQCNLHGSVNKFCNPHSGQC--ECKKEAKGLQCDT 779
Score = 85.9 bits (211), Expect = 3e-16
Identities = 63/216 (29%), Positives = 94/216 (43%), Gaps = 47/216 (21%)
Query: 74 TLSGECVPCDCNGNSNEC-LDGSGYCVHCQRN--TTGEHCEKCLDGYIGDSIRGAPQF-- 128
T+SG C C+G+++ C Y C + T G HC++CL Y R Q
Sbjct: 513 TISGRC---QCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569
Query: 129 --CQPCPCPLPHLANFAESC-------------YRKNGAVRCICNENYAGPNCERCAPGY 173
C+PC C + ++SC +R G V C N G NCE C +
Sbjct: 570 FNCKPCQC-----NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYF 624
Query: 174 Y----GNPLLIGSTCKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG 227
+ +P I CK CDC G + +++ CD++ GQC NC R+ +G +C +C G
Sbjct: 625 FRQVGADPSAI-DVCKPCDCDTVGTRNGSIL---CDQIGGQC-NCKRHVSGRQCNQCQNG 679
Query: 228 YYGDARI-AKNCAVCNC-------GGGPCDSVTGEC 255
+Y + C+ CNC G C +G+C
Sbjct: 680 FYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQC 715
Score = 85.9 bits (211), Expect = 3e-16
Identities = 63/211 (29%), Positives = 91/211 (43%), Gaps = 35/211 (16%)
Query: 65 EKCNAGFFHTLSGE---CVPCDCN--GNSNE-CLDGSGYCVHCQRNTTGEHCEKCLDGYI 118
+ CN GF S C PC CN G+ N+ C SG C C++ G C+ C + +
Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAKGLQCDTCRENFY 785
Query: 119 GDSIRGAPQFCQPCPC----PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
G + C+ C C LP C K G +CIC N G C +C G +
Sbjct: 786 GLDVTN----CKACDCDTAGSLP-----GTVCNAKTG--QCICKPNVEGRQCNKCLEGNF 834
Query: 175 GNPLLIGSTCKKCDC--SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-D 231
C C+C +G + +L+ C++ TGQC C TG +C +C P Y
Sbjct: 835 YLRQNNSFLCLPCNCDKTGTINGSLL---CNKSTGQC-PCKLGVTGLRCNQCEPHRYNLT 890
Query: 232 ARIAKNCAVCNCG------GGPCDSVTGECL 256
++C +C C G CD ++G+CL
Sbjct: 891 IDNFQHCQMCECDSLGTLPGTICDPISGQCL 921
Score = 81.3 bits (199), Expect = 8e-15
Identities = 68/229 (29%), Positives = 92/229 (40%), Gaps = 37/229 (16%)
Query: 66 KCNAGFFHTLSGE---CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117
KC G F+ C+PC+C+ S C +G C C+ TG C +C
Sbjct: 828 KCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCP-CKLGVTGLRCNQCEPHR 886
Query: 118 IGDSIRGAPQFCQPCPCP----LPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGY 173
+I Q CQ C C LP C +G +C+C N G C +C PG+
Sbjct: 887 YNLTIDNF-QHCQMCECDSLGTLP-----GTICDPISG--QCLCVPNRQGRRCNQCQPGF 938
Query: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR 233
Y +P + C C C N I C+ +TGQC + G +C++C Y+G
Sbjct: 939 YISPGN-ATGCLPCSCHTTGAVNHI---CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDP 994
Query: 234 IAKNCAVCNCG-----GGPCDSVTGECLEEGFEPPTGMDCPTISCDKCV 277
C CNC C VTG+C + F TG CD CV
Sbjct: 995 QTGRCQPCNCHLSGALNETCHLVTGQCFCKQF--VTGS-----KCDACV 1036
Score = 66.6 bits (161), Expect = 2e-10
Identities = 48/153 (31%), Positives = 65/153 (42%), Gaps = 17/153 (11%)
Query: 79 CVPCDCNG----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPC 134
C C+C+ C SG C+ C N G C +C G+ G C PC C
Sbjct: 897 CQMCECDSLGTLPGTICDPISGQCL-CVPNRQGRRCNQCQPGFYISP--GNATGCLPCSC 953
Query: 135 PLPHLANFAESCYRKNGAVRCICNE-NYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNS 193
N C G +C+C + + AG C++C Y+G G C+ C+C +
Sbjct: 954 HTTGAVNHI--CNSLTG--QCVCQDASIAGQRCDQCKDHYFGFDPQTGR-CQPCNCHLSG 1008
Query: 194 DPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226
N E C VTGQC C + TG KC+ C P
Sbjct: 1009 ALN---ETCHLVTGQCF-CKQFVTGSKCDACVP 1037
Score = 59.7 bits (143), Expect = 3e-08
Identities = 35/112 (31%), Positives = 52/112 (46%), Gaps = 13/112 (11%)
Query: 66 KCNAGFFHTLSGE--CVPCDCNGN---SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG- 119
+C GF+ + C+PC C+ ++ C +G CV + G+ C++C D Y G
Sbjct: 933 QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992
Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAP 171
D G CQPC C L N E+C+ G +C C + G C+ C P
Sbjct: 993 DPQTGR---CQPCNCHLSGALN--ETCHLVTG--QCFCKQFVTGSKCDACVP 1037
>gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]
Length = 1547
Score = 87.4 bits (215), Expect = 1e-16
Identities = 163/849 (19%), Positives = 315/849 (37%), Gaps = 136/849 (16%)
Query: 1052 FDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFY 1111
F GS Y D+++ + +T NGL+L + + L ++NG + +
Sbjct: 319 FKGSEYFCY-DLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVI 377
Query: 1112 DFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMIL---VVDRRHVK---SMDNEK 1165
+ G +E + ND +H++ + + + + +V++ H S+D
Sbjct: 378 NLGSGAFEALVEPV--NGKFNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGIL 435
Query: 1166 MKIPFTD-----------IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNL 1214
+T Y+GG+P S A P+ NF GC+K ++ D L
Sbjct: 436 TTTGYTQEDYTMLGSDDFFYVGGSP-----STADLPGSPVSNNFMGCLKEVVYKNNDVRL 490
Query: 1215 -LEQTETLG---------VGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFR 1264
L + G V + C + + + +SFI S+ K + F+FR
Sbjct: 491 ELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFI-SLPKWNAKKTGSISFDFR 549
Query: 1265 TLQPNGLLFYYASGS--------------DVFSISLDNGTV--IMDVKG--IKVQSVDKQ 1306
T +PNGL+ + D F+I + +G + ++D+ IK++++ K+
Sbjct: 550 TTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKK 609
Query: 1307 YNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSP------- 1359
NDG + V + V+ R P + +I + + Y GG P
Sbjct: 610 VNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDL---DDELYLGGLPENKAGLV 666
Query: 1360 ------ISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLH 1413
+ + GCI + + +D+ + T V S
Sbjct: 667 FPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSC-------------- 712
Query: 1414 KKGKNLSKPKASQN-KKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQY 1472
K +KP S K G +D W+ +L S Y
Sbjct: 713 --SKETAKPCLSNPCKNNGMCRDG--WNRYVCDCSGTG-------YLGRSCEREATVLSY 761
Query: 1473 GGTANSRQEFE---HLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRL 1529
G+ + + H + + S+R R++ ++G++ + ++ D + L L GR+
Sbjct: 762 DGSMFMKIQLPVVMHTEAE-----DVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRV 816
Query: 1530 VYMFNVGHKKLKIRSQE---------KYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLP 1580
N+ ++ S + ND WH V +R S +L +D + + +
Sbjct: 817 KLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMA 876
Query: 1581 PTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPC 1640
+ I G + + + +V N F G L +L NG + + + C
Sbjct: 877 GDHTRLEFHN-IETGIITERRYLSSVPSN----FIGHLQSLTFNGMAYIDLCKNGDIDYC 931
Query: 1641 -------FEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNG 1693
F + F T+ YV L + + F+ + S G +++
Sbjct: 932 ELNARFGFRNIIADPVTFKTKSSYVAL-ATLQAYTSMHLFFQFKTTSLDGLILYNSGDGN 990
Query: 1694 EYLNVHMKNGQV--IVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRD-SNVVQLDVDSE 1750
+++ V + G + + + NG S + L D +WH + + RD SN+ + +D++
Sbjct: 991 DFIVVELVKGYLHYVFDLGNGANLIKGS--SNKPLNDNQWHNVMISRDTSNLHTVKIDTK 1048
Query: 1751 VNHVVGPLNPKPIDHREPVFVGGVPESLL--TPRLAPSKP-FTGCIRHFVIDGH-PVSFS 1806
+ + + +D + +++GGV + P+L +K F GC+ ++G P S
Sbjct: 1049 ITTQI-TAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLIS 1107
Query: 1807 KAALVSGAV 1815
A +G +
Sbjct: 1108 DALFCNGQI 1116
Score = 56.2 bits (134), Expect = 3e-07
Identities = 87/371 (23%), Positives = 143/371 (38%), Gaps = 48/371 (12%)
Query: 893 EYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIER-------VGKHGKV 945
+Y+ LA+KN + V NLG+ E ++ + VK+ R +G H V
Sbjct: 362 DYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIG-HAMV 420
Query: 946 FLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGC 1005
S++ + + G D ++L D FYVGG PS LP S F+GC
Sbjct: 421 NKLHCSVTISVDGILTTTGYTQEDYTMLG---SDDFFYVGGSPSTADLPGSPVSNNFMGC 477
Query: 1006 LELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITR 1065
L+ N+ + L + DP + +AF A+ D +
Sbjct: 478 LKEVVYKNNDVRLELSRLAKQGDPKMKI---HGVVAFKCENVAT--LDPITFETPESFIS 532
Query: 1066 RGKFG--QVTRFDIEVRTPADNGLILL---------------MVNGSMFFRLEMRNGYLH 1108
K+ + + RT NGLIL M+ FF +EM +G+L+
Sbjct: 533 LPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVD-FFAIEMLDGHLY 591
Query: 1109 VFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKI 1168
+ D G G + ++ LKK +ND +++ + I V R + E +
Sbjct: 592 LLLDMG--SGTIKIKALLKK--VNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEIL 647
Query: 1169 PFTD-IYIGGAPPE----ILQSRALRAHLPLDINFRGCMKG--FQFQKKDF-NLLEQTET 1220
D +Y+GG P + + A L+ + GC++ Q KD + E T
Sbjct: 648 DLDDELYLGGLPENKAGLVFPTEVWTA--LLNYGYVGCIRDLFIDGQSKDIRQMAEVQST 705
Query: 1221 LGVGYGCPEDS 1231
GV C +++
Sbjct: 706 AGVKPSCSKET 716
Score = 50.1 bits (118), Expect = 2e-05
Identities = 35/144 (24%), Positives = 68/144 (47%), Gaps = 7/144 (4%)
Query: 1492 KSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAH-GRLVYMFNV-GHKKLKIRSQEKYN 1549
+S+ S +L+TRS+ G++ Y D+ DF+ L L GRL F++ + + + N
Sbjct: 51 ESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVN 110
Query: 1550 DGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAP--GKAVKNVQ 1607
DG WH V R+ + L ID + + + +++GG+ P A +
Sbjct: 111 DGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLT 170
Query: 1608 INSIYS---FSGCLSNLQLNGASI 1628
+ S+ F G + ++++N + +
Sbjct: 171 LASVREREPFKGWIRDVRVNSSQV 194
Score = 47.8 bits (112), Expect = 1e-04
Identities = 145/764 (18%), Positives = 275/764 (35%), Gaps = 143/764 (18%)
Query: 891 KKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVP 950
K ++ + + + +L + ++G+ ++I K V+ Y V +R G+ G + +
Sbjct: 577 KVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYH--VDFQRDGRSGTISVNTL 634
Query: 951 SLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSN-------FKLPTSLNLPGFV 1003
TA G+ +LDLD E Y+GG+P N ++ T+L G+V
Sbjct: 635 RTPYTAP----------GESEILDLDDE---LYLGGLPENKAGLVFPTEVWTALLNYGYV 681
Query: 1004 GCLE---LATLNNDVISLYNFKHIYNMDPSTSVPCARDKLA-------FTQSRAASYFFD 1053
GC+ + + D+ + + + PS S A+ L+ + Y D
Sbjct: 682 GCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCD 741
Query: 1054 --GSGY---AVVRDITRRGKFGQV------------TRFDIEVRTPADNGLILLMVNGSM 1096
G+GY + R+ T G + D+ +R + +LM S
Sbjct: 742 CSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSR 801
Query: 1097 ----FFRLEMRNGYLHVFYDF-------GFSGGPVHLEDTLKKAQINDAKYHEISIIYHN 1145
RLE+ G + + + S GP E +ND ++H + ++
Sbjct: 802 DSADTLRLELDAGRVKLTVNLDCIRINCNSSKGP---ETLFAGYNLNDNEWHTVRVV-RR 857
Query: 1146 DKKMILVVDRRHVKS--MDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMK 1203
K + L VD + + M + ++ F +I G I+ R + +P NF G ++
Sbjct: 858 GKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETG-----IITERRYLSSVPS--NFIGHLQ 910
Query: 1204 GFQF---------QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFF 1254
F + D + E G ++I+ F +S ++ + +
Sbjct: 911 SLTFNGMAYIDLCKNGDIDYCELNARFGFR------NIIADPVTFKTKSSYVALATLQAY 964
Query: 1255 DGFEGGFNFRTLQPNGLLFYYAS-GSDVFSISLDNGTV--IMDV---KGIKVQSVDKQYN 1308
F F+T +GL+ Y + G+D + L G + + D+ + S +K N
Sbjct: 965 TSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLN 1024
Query: 1309 DGLSHFVISSVSPTRYELIVDKSRV------GSKNPTKGKIEQTQASEKKFYFGGSPISA 1362
D H V+ S + + +++ G++N K+ Y +
Sbjct: 1025 DNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVH 1084
Query: 1363 QYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKP 1422
F GC+++ VD + + D + S LF + + P
Sbjct: 1085 AKEGFQGCLAS-----VDLNGRLPD----------------LISDALFCNGQIERGCEGP 1123
Query: 1423 KASQNKKGGKSKDA--PSWDPVALKL-------PERNTPRNSHCHLSNSPRAIEHAYQYG 1473
+ + ++ WD + P N P ++ + Y++
Sbjct: 1124 STTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQI---TYKWP 1180
Query: 1474 GTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMF 1533
+ L F + ++ +R SS G+ D++ L + G++ F
Sbjct: 1181 PNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGL---------GDYLELHIHQGKIGVKF 1231
Query: 1534 NVGHKKLKIR-SQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLE 1576
NVG + I S NDG +H V F R + L +D V+E
Sbjct: 1232 NVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIE 1275
Score = 47.4 bits (111), Expect = 1e-04
Identities = 71/390 (18%), Positives = 140/390 (35%), Gaps = 74/390 (18%)
Query: 1491 AKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQE---K 1547
+ + ++ +T +G++ + + D++ L L +G + + N+G + + K
Sbjct: 337 SSDEITLSFKTLQRNGLMLHTG--KSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGK 394
Query: 1548 YNDGLWHDVIFIRE---------------RSSGRLVIDGLRVLEESLPPTEATWKIKGP- 1591
+ND WHDV R S + +DG+ + T+ + + G
Sbjct: 395 FNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILT---TTGYTQEDYTMLGSD 451
Query: 1592 --IYLGGVA-----PGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFS-------- 1636
Y+GG PG V N +F GCL + + +
Sbjct: 452 DFFYVGGSPSTADLPGSPVSN-------NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMK 504
Query: 1637 -----VTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHS- 1690
C F T ++ L + +N I+F+ R +G ++ H
Sbjct: 505 IHGVVAFKCENVATLDPITFETPESFISLPK-WNAKKTGSISFDFRTTEPNGLILFSHGK 563
Query: 1691 ------------VNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIR 1738
+ ++ + M +G + + ++ G K+ + DG W+ + R
Sbjct: 564 PRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKK-VNDGEWYHVDFQR 622
Query: 1739 DSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPES---LLTP----RLAPSKPFTG 1791
D + V++ P + +D + +++GG+PE+ L+ P + + G
Sbjct: 623 DGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVG 682
Query: 1792 CIRHFVIDGHPVSFSKAALVSGAVSIN-SC 1820
CIR IDG + A V + SC
Sbjct: 683 CIRDLFIDGQSKDIRQMAEVQSTAGVKPSC 712
Score = 35.8 bits (81), Expect = 0.39
Identities = 37/142 (26%), Positives = 61/142 (42%), Gaps = 21/142 (14%)
Query: 1067 GKFGQVTRF-----------DIEVRTPADNGLILLMVNGSMFFRLEM---RNGYLHVFYD 1112
G GQ TRF +++T + GL+L + LE+ R G L + +
Sbjct: 35 GAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFS 94
Query: 1113 FGFSGGPVHLEDTLKKAQINDAKYHEISII--YHNDKKMILVVDRRHVKSMDNEKMKIPF 1170
F P L L +ND +H + I + N I V+ + V+ + F
Sbjct: 95 I-FCAEPATL---LADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVF 150
Query: 1171 TDIYIGGAPPEILQSRALRAHL 1192
+ +++GG PPE L++ AL+ L
Sbjct: 151 SGLFVGGLPPE-LRAAALKLTL 171
>gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]
Length = 1477
Score = 87.4 bits (215), Expect = 1e-16
Identities = 162/843 (19%), Positives = 311/843 (36%), Gaps = 131/843 (15%)
Query: 1052 FDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFY 1111
F GS Y D+++ + +T NGL+L + + L ++NG + +
Sbjct: 286 FKGSEYFCY-DLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVI 344
Query: 1112 DFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKIPFT 1171
+ G +E + ND +H++ + N ++ + S+D +T
Sbjct: 345 NLGSGAFEALVEPV--NGKFNDNAWHDVKVT-RNLRQHSGIGHAMVTISVDGILTTTGYT 401
Query: 1172 D-----------IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNL-LEQTE 1219
Y+GG+P S A P+ NF GC+K ++ D L L +
Sbjct: 402 QEDYTMLGSDDFFYVGGSP-----STADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLA 456
Query: 1220 TLG---------VGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQPNG 1270
G V + C + + + +SFI S+ K + F+FRT +PNG
Sbjct: 457 KQGDPKMKIHGVVAFKCENVATLDPITFETPESFI-SLPKWNAKKTGSISFDFRTTEPNG 515
Query: 1271 LLFYYASGS--------------DVFSISLDNGTV--IMDVKG--IKVQSVDKQYNDGLS 1312
L+ + D F+I + +G + ++D+ IK++++ K+ NDG
Sbjct: 516 LILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEW 575
Query: 1313 HFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSP------------- 1359
+ V + V+ R P + +I + + Y GG P
Sbjct: 576 YHVDFQRDGRSGTISVNTLRTPYTAPGESEILDL---DDELYLGGLPENKAGLVFPTEVW 632
Query: 1360 ISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNL 1419
+ + GCI + + +D+ + T V S K
Sbjct: 633 TALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSC----------------SKET 676
Query: 1420 SKPKASQN-KKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANS 1478
+KP S K G +D W+ +L S Y G+
Sbjct: 677 AKPCLSNPCKNNGMCRDG--WNRYVCDCSGTG-------YLGRSCEREATVLSYDGSMFM 727
Query: 1479 RQEFE---HLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNV 1535
+ + H + + S+R R++ ++G++ + ++ D + L L GR+ N+
Sbjct: 728 KIQLPVVMHTEAE-----DVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNL 782
Query: 1536 GHKKLKIRSQE---------KYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATW 1586
++ S + ND WH V +R S +L +D + + +
Sbjct: 783 DCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRL 842
Query: 1587 KIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPC------ 1640
+ I G + + + +V N F G L +L NG + + + C
Sbjct: 843 EFHN-IETGIITERRYLSSVPSN----FIGHLQSLTFNGMAYIDLCKNGDIDYCELNARF 897
Query: 1641 -FEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVH 1699
F + F T+ YV L + + F+ + S G +++ +++ V
Sbjct: 898 GFRNIIADPVTFKTKSSYVAL-ATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVE 956
Query: 1700 MKNGQV--IVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRD-SNVVQLDVDSEVNHVVG 1756
+ G + + + NG S + L D +WH + + RD SN+ + +D+++ +
Sbjct: 957 LVKGYLHYVFDLGNGANLIKGS--SNKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQI- 1013
Query: 1757 PLNPKPIDHREPVFVGGVPESLL--TPRLAPSKP-FTGCIRHFVIDGH-PVSFSKAALVS 1812
+ +D + +++GGV + P+L +K F GC+ ++G P S A +
Sbjct: 1014 TAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCN 1073
Query: 1813 GAV 1815
G +
Sbjct: 1074 GQI 1076
Score = 58.2 bits (139), Expect = 7e-08
Identities = 88/371 (23%), Positives = 144/371 (38%), Gaps = 55/371 (14%)
Query: 893 EYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIER-------VGKHGKV 945
+Y+ LA+KN + V NLG+ E ++ + VK+ R +G H V
Sbjct: 329 DYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIG-HAMV 387
Query: 946 FLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGC 1005
++V + +T G D ++L D FYVGG PS LP S F+GC
Sbjct: 388 TISVDGILTTT-------GYTQEDYTMLG---SDDFFYVGGSPSTADLPGSPVSNNFMGC 437
Query: 1006 LELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITR 1065
L+ N+ + L + DP + +AF A+ D +
Sbjct: 438 LKEVVYKNNDVRLELSRLAKQGDPKMKI---HGVVAFKCENVAT--LDPITFETPESFIS 492
Query: 1066 RGKFG--QVTRFDIEVRTPADNGLILL---------------MVNGSMFFRLEMRNGYLH 1108
K+ + + RT NGLIL M+ FF +EM +G+L+
Sbjct: 493 LPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVD-FFAIEMLDGHLY 551
Query: 1109 VFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKI 1168
+ D G G + ++ LKK +ND +++ + I V R + E +
Sbjct: 552 LLLDMG--SGTIKIKALLKK--VNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEIL 607
Query: 1169 PFTD-IYIGGAPPE----ILQSRALRAHLPLDINFRGCMKG--FQFQKKDF-NLLEQTET 1220
D +Y+GG P + + A L+ + GC++ Q KD + E T
Sbjct: 608 DLDDELYLGGLPENKAGLVFPTEVWTA--LLNYGYVGCIRDLFIDGQSKDIRQMAEVQST 665
Query: 1221 LGVGYGCPEDS 1231
GV C +++
Sbjct: 666 AGVKPSCSKET 676
Score = 53.1 bits (126), Expect = 2e-06
Identities = 157/817 (19%), Positives = 293/817 (35%), Gaps = 155/817 (18%)
Query: 891 KKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVP 950
K ++ + + + +L + ++G+ ++I K V+ Y V +R G+ G + +
Sbjct: 537 KVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYH--VDFQRDGRSGTISVNTL 594
Query: 951 SLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSN-------FKLPTSLNLPGFV 1003
TA G+ +LDLD E Y+GG+P N ++ T+L G+V
Sbjct: 595 RTPYTAP----------GESEILDLDDE---LYLGGLPENKAGLVFPTEVWTALLNYGYV 641
Query: 1004 GCLE---LATLNNDVISLYNFKHIYNMDPSTSVPCARDKLA-------FTQSRAASYFFD 1053
GC+ + + D+ + + + PS S A+ L+ + Y D
Sbjct: 642 GCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCD 701
Query: 1054 --GSGY---AVVRDITRRGKFGQV------------TRFDIEVRTPADNGLILLMVNGSM 1096
G+GY + R+ T G + D+ +R + +LM S
Sbjct: 702 CSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSR 761
Query: 1097 ----FFRLEMRNGYLHVFYDF-------GFSGGPVHLEDTLKKAQINDAKYHEISIIYHN 1145
RLE+ G + + + S GP E +ND ++H + ++
Sbjct: 762 DSADTLRLELDAGRVKLTVNLDCIRINCNSSKGP---ETLFAGYNLNDNEWHTVRVV-RR 817
Query: 1146 DKKMILVVDRRHVKS--MDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMK 1203
K + L VD + + M + ++ F +I G I+ R + +P NF G ++
Sbjct: 818 GKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETG-----IITERRYLSSVPS--NFIGHLQ 870
Query: 1204 GFQF---------QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFF 1254
F + D + E G ++I+ F +S ++ + +
Sbjct: 871 SLTFNGMAYIDLCKNGDIDYCELNARFGFR------NIIADPVTFKTKSSYVALATLQAY 924
Query: 1255 DGFEGGFNFRTLQPNGLLFYYAS-GSDVFSISLDNGTV--IMDV---KGIKVQSVDKQYN 1308
F F+T +GL+ Y + G+D + L G + + D+ + S +K N
Sbjct: 925 TSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLN 984
Query: 1309 DGLSHFVISSVSPTRYELIVDKSRV------GSKNPTKGKIEQTQASEKKFYFGGSPISA 1362
D H V+ S + + +++ G++N K+ Y +
Sbjct: 985 DNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVH 1044
Query: 1363 QYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKP 1422
F GC+++ VD + + D + S LF + + P
Sbjct: 1045 AKEGFQGCLAS-----VDLNGRLPD----------------LISDALFCNGQIERGCEGP 1083
Query: 1423 KASQNKKGGKSKDA--PSWDPVALKL-------PERNTPRNSHCHLSNSPRAIEHAYQYG 1473
+ + ++ WD + P N P ++ + Y++
Sbjct: 1084 STTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQI---TYKWP 1140
Query: 1474 GTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMF 1533
+ L F + ++ +R SS G+ D++ L + G++ F
Sbjct: 1141 PNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGL---------GDYLELHIHQGKIGVKF 1191
Query: 1534 NVGHKKLKIR-SQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEAT-WKIKGP 1591
NVG + I S NDG +H V F R + L +D V+E + T + +
Sbjct: 1192 NVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQAT 1251
Query: 1592 IYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASI 1628
I +GG G+ F G LS L NG +
Sbjct: 1252 IIIGGKEQGQ-----------PFQGQLSGLYYNGLKV 1277
Score = 50.1 bits (118), Expect = 2e-05
Identities = 35/144 (24%), Positives = 68/144 (47%), Gaps = 7/144 (4%)
Query: 1492 KSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAH-GRLVYMFNV-GHKKLKIRSQEKYN 1549
+S+ S +L+TRS+ G++ Y D+ DF+ L L GRL F++ + + + N
Sbjct: 51 ESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVN 110
Query: 1550 DGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAP--GKAVKNVQ 1607
DG WH V R+ + L ID + + + +++GG+ P A +
Sbjct: 111 DGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLT 170
Query: 1608 INSIYS---FSGCLSNLQLNGASI 1628
+ S+ F G + ++++N + +
Sbjct: 171 LASVREREPFKGWIRDVRVNSSQV 194
Score = 49.7 bits (117), Expect = 3e-05
Identities = 72/383 (18%), Positives = 142/383 (37%), Gaps = 67/383 (17%)
Query: 1491 AKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQE---K 1547
+ + ++ +T +G++ + + D++ L L +G + + N+G + + K
Sbjct: 304 SSDEITLSFKTLQRNGLMLHTG--KSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGK 361
Query: 1548 YNDGLWHDVIFIRE--RSSG------RLVIDGLRVLEESLPPTEATWKIKGP---IYLGG 1596
+ND WHDV R + SG + +DG+ + T+ + + G Y+GG
Sbjct: 362 FNDNAWHDVKVTRNLRQHSGIGHAMVTISVDGILT---TTGYTQEDYTMLGSDDFFYVGG 418
Query: 1597 VA-----PGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFS-------------VT 1638
PG V N +F GCL + + +
Sbjct: 419 SPSTADLPGSPVSN-------NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAF 471
Query: 1639 PCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHS-------- 1690
C F T ++ L + +N I+F+ R +G ++ H
Sbjct: 472 KCENVATLDPITFETPESFISLPK-WNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDA 530
Query: 1691 -----VNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQL 1745
+ ++ + M +G + + ++ G K+ + DG W+ + RD +
Sbjct: 531 KHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKK-VNDGEWYHVDFQRDGRSGTI 589
Query: 1746 DVDSEVNHVVGPLNPKPIDHREPVFVGGVPES---LLTP----RLAPSKPFTGCIRHFVI 1798
V++ P + +D + +++GG+PE+ L+ P + + GCIR I
Sbjct: 590 SVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFI 649
Query: 1799 DGHPVSFSKAALVSGAVSIN-SC 1820
DG + A V + SC
Sbjct: 650 DGQSKDIRQMAEVQSTAGVKPSC 672
Score = 35.8 bits (81), Expect = 0.39
Identities = 37/142 (26%), Positives = 61/142 (42%), Gaps = 21/142 (14%)
Query: 1067 GKFGQVTRF-----------DIEVRTPADNGLILLMVNGSMFFRLEM---RNGYLHVFYD 1112
G GQ TRF +++T + GL+L + LE+ R G L + +
Sbjct: 35 GAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFS 94
Query: 1113 FGFSGGPVHLEDTLKKAQINDAKYHEISII--YHNDKKMILVVDRRHVKSMDNEKMKIPF 1170
F P L L +ND +H + I + N I V+ + V+ + F
Sbjct: 95 I-FCAEPATL---LADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVF 150
Query: 1171 TDIYIGGAPPEILQSRALRAHL 1192
+ +++GG PPE L++ AL+ L
Sbjct: 151 SGLFVGGLPPE-LRAAALKLTL 171
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,235,174
Number of Sequences: 37866
Number of extensions: 3253346
Number of successful extensions: 13893
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 123
Number of HSP's successfully gapped in prelim test: 669
Number of HSP's that attempted gapping in prelim test: 9673
Number of HSP's gapped (non-prelim): 2889
length of query: 1823
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1706
effective length of database: 13,817,196
effective search space: 23572136376
effective search space used: 23572136376
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.