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Search of human proteins with 157419122
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo
sapiens]
(1816 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 3655 0.0
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 3655 0.0
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 3648 0.0
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 831 0.0
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 804 0.0
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 799 0.0
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 755 0.0
gi|21264602 laminin alpha 5 [Homo sapiens] 687 0.0
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 421 e-117
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 419 e-116
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 394 e-109
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 171 5e-42
gi|143770880 laminin, beta 4 [Homo sapiens] 164 6e-40
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 159 3e-38
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 159 3e-38
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 145 3e-34
gi|157419130 laminin, alpha 4 isoform 3 precursor [Homo sapiens] 135 3e-31
gi|157419128 laminin, alpha 4 isoform 3 precursor [Homo sapiens] 135 3e-31
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 132 4e-30
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 131 7e-30
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 129 2e-29
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 128 6e-29
gi|219842266 usherin isoform B [Homo sapiens] 106 2e-22
gi|93204871 netrin 4 [Homo sapiens] 102 3e-21
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 100 2e-20
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 100 2e-20
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 100 2e-20
gi|219842259 usherin isoform A [Homo sapiens] 92 4e-18
gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens] 87 1e-16
gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens] 87 1e-16
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 3655 bits (9478), Expect = 0.0
Identities = 1816/1816 (100%), Positives = 1816/1816 (100%)
Query: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
Sbjct: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
Query: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
Sbjct: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
Sbjct: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
Query: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
Sbjct: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
Query: 241 CNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAA 300
CNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAA
Sbjct: 241 CNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAA 300
Query: 301 HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG 360
HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG
Sbjct: 301 HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG 360
Query: 361 QLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKML 420
QLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKML
Sbjct: 361 QLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKML 420
Query: 421 EEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSD 480
EEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSD
Sbjct: 421 EEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSD 480
Query: 481 LQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT 540
LQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT
Sbjct: 481 LQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT 540
Query: 541 LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK 600
LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK
Sbjct: 541 LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK 600
Query: 601 LHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD 660
LHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD
Sbjct: 601 LHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD 660
Query: 661 ESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDA 720
ESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDA
Sbjct: 661 ESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDA 720
Query: 721 QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN 780
QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN
Sbjct: 721 QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN 780
Query: 781 LTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVH 840
LTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVH
Sbjct: 781 LTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVH 840
Query: 841 SRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYV 900
SRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYV
Sbjct: 841 SRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYV 900
Query: 901 YNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS 960
YNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS
Sbjct: 901 YNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS 960
Query: 961 GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM 1020
GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM
Sbjct: 961 GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM 1020
Query: 1021 DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL 1080
DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL
Sbjct: 1021 DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL 1080
Query: 1081 ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDK 1140
ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDK
Sbjct: 1081 ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDK 1140
Query: 1141 KMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQF 1200
KMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQF
Sbjct: 1141 KMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQF 1200
Query: 1201 QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ 1260
QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ
Sbjct: 1201 QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ 1260
Query: 1261 PNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELI 1320
PNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELI
Sbjct: 1261 PNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELI 1320
Query: 1321 VDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVED 1380
VDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVED
Sbjct: 1321 VDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVED 1380
Query: 1381 FQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLP 1440
FQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLP
Sbjct: 1381 FQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLP 1440
Query: 1441 ERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGM 1500
ERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGM
Sbjct: 1441 ERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGM 1500
Query: 1501 IFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRL 1560
IFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRL
Sbjct: 1501 IFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRL 1560
Query: 1561 VIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGAS 1620
VIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGAS
Sbjct: 1561 VIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGAS 1620
Query: 1621 ITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH 1680
ITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH
Sbjct: 1621 ITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH 1680
Query: 1681 GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDV 1740
GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDV
Sbjct: 1681 GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDV 1740
Query: 1741 DSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1800
DSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK
Sbjct: 1741 DSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1800
Query: 1801 AALVSGAVSINSCPAA 1816
AALVSGAVSINSCPAA
Sbjct: 1801 AALVSGAVSINSCPAA 1816
>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 3655 bits (9478), Expect = 0.0
Identities = 1816/1816 (100%), Positives = 1816/1816 (100%)
Query: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
Sbjct: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
Query: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
Sbjct: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
Sbjct: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
Query: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
Sbjct: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
Query: 241 CNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAA 300
CNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAA
Sbjct: 241 CNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAA 300
Query: 301 HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG 360
HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG
Sbjct: 301 HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKG 360
Query: 361 QLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKML 420
QLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKML
Sbjct: 361 QLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKML 420
Query: 421 EEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSD 480
EEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSD
Sbjct: 421 EEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSD 480
Query: 481 LQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT 540
LQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT
Sbjct: 481 LQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLT 540
Query: 541 LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK 600
LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK
Sbjct: 541 LSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRK 600
Query: 601 LHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD 660
LHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD
Sbjct: 601 LHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD 660
Query: 661 ESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDA 720
ESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDA
Sbjct: 661 ESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDA 720
Query: 721 QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN 780
QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN
Sbjct: 721 QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN 780
Query: 781 LTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVH 840
LTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVH
Sbjct: 781 LTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVH 840
Query: 841 SRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYV 900
SRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYV
Sbjct: 841 SRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYV 900
Query: 901 YNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS 960
YNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS
Sbjct: 901 YNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFS 960
Query: 961 GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM 1020
GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM
Sbjct: 961 GDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNM 1020
Query: 1021 DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL 1080
DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL
Sbjct: 1021 DPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGL 1080
Query: 1081 ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDK 1140
ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDK
Sbjct: 1081 ILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDK 1140
Query: 1141 KMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQF 1200
KMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQF
Sbjct: 1141 KMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQF 1200
Query: 1201 QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ 1260
QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ
Sbjct: 1201 QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ 1260
Query: 1261 PNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELI 1320
PNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELI
Sbjct: 1261 PNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELI 1320
Query: 1321 VDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVED 1380
VDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVED
Sbjct: 1321 VDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVED 1380
Query: 1381 FQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLP 1440
FQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLP
Sbjct: 1381 FQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLP 1440
Query: 1441 ERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGM 1500
ERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGM
Sbjct: 1441 ERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGM 1500
Query: 1501 IFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRL 1560
IFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRL
Sbjct: 1501 IFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRL 1560
Query: 1561 VIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGAS 1620
VIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGAS
Sbjct: 1561 VIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGAS 1620
Query: 1621 ITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH 1680
ITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH
Sbjct: 1621 ITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH 1680
Query: 1681 GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDV 1740
GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDV
Sbjct: 1681 GHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDV 1740
Query: 1741 DSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1800
DSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK
Sbjct: 1741 DSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSK 1800
Query: 1801 AALVSGAVSINSCPAA 1816
AALVSGAVSINSCPAA
Sbjct: 1801 AALVSGAVSINSCPAA 1816
>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
Length = 1823
Score = 3648 bits (9460), Expect = 0.0
Identities = 1816/1823 (99%), Positives = 1816/1823 (99%), Gaps = 7/1823 (0%)
Query: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
Sbjct: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
Query: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD
Sbjct: 61 PPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
Query: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI
Sbjct: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
Query: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV
Sbjct: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
Query: 241 CNCGGGPCDSVTGECLEEGFEPPTG-------CDKCVWDLTDALRLAALSIEEGKSGVLS 293
CNCGGGPCDSVTGECLEEGFEPPTG CDKCVWDLTDALRLAALSIEEGKSGVLS
Sbjct: 241 CNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDALRLAALSIEEGKSGVLS 300
Query: 294 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE 353
VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE
Sbjct: 301 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKE 360
Query: 354 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL 413
NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL
Sbjct: 361 NQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKL 420
Query: 414 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD 473
VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD
Sbjct: 421 VLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDD 480
Query: 474 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS 533
YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS
Sbjct: 481 YNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADS 540
Query: 534 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 593
LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE
Sbjct: 541 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 600
Query: 594 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT 653
ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT
Sbjct: 601 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDT 660
Query: 654 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ 713
QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ
Sbjct: 661 QIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQ 720
Query: 714 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS 773
AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS
Sbjct: 721 AAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNS 780
Query: 774 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG 833
ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG
Sbjct: 781 ARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDG 840
Query: 834 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK 893
QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK
Sbjct: 841 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK 900
Query: 894 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF 953
NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF
Sbjct: 901 NDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKF 960
Query: 954 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN 1013
IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN
Sbjct: 961 IKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYN 1020
Query: 1014 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR 1073
FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR
Sbjct: 1021 FKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVR 1080
Query: 1074 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS 1133
TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS
Sbjct: 1081 TPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEIS 1140
Query: 1134 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG 1193
IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG
Sbjct: 1141 IIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRG 1200
Query: 1194 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG 1253
CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG
Sbjct: 1201 CMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGG 1260
Query: 1254 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS 1313
FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS
Sbjct: 1261 FNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVS 1320
Query: 1314 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD 1373
PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD
Sbjct: 1321 PTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVD 1380
Query: 1374 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD 1433
RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD
Sbjct: 1381 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD 1440
Query: 1434 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR 1493
PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR
Sbjct: 1441 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR 1500
Query: 1494 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR 1553
TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR
Sbjct: 1501 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR 1560
Query: 1554 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN 1613
ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN
Sbjct: 1561 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN 1620
Query: 1614 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS 1673
LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS
Sbjct: 1621 LQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRS 1680
Query: 1674 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS 1733
SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS
Sbjct: 1681 SSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDS 1740
Query: 1734 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG 1793
NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG
Sbjct: 1741 NVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDG 1800
Query: 1794 HPVSFSKAALVSGAVSINSCPAA 1816
HPVSFSKAALVSGAVSINSCPAA
Sbjct: 1801 HPVSFSKAALVSGAVSINSCPAA 1823
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 831 bits (2147), Expect = 0.0
Identities = 559/1815 (30%), Positives = 892/1815 (49%), Gaps = 155/1815 (8%)
Query: 40 SAVGRQDPPETSEPRVALG----RLPPA-----AEKCNAGFFHT----LSGECVPCDCNG 86
S VG ++ +T R+AL PPA + C+ G++ +G CVPC+CNG
Sbjct: 1632 SEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNG 1691
Query: 87 NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESC 146
+SN+C DGSG CV+CQ NT GEHCE+C +GY G+++ G+ C+ CPC PH +FA C
Sbjct: 1692 HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS---CRACPC--PHTNSFATGC 1746
Query: 147 YRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVT 206
G VRC C Y G CERCAPGY+GNP G +C+ C C+ N C +T
Sbjct: 1747 VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLT 1802
Query: 207 GQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGC 266
G C N P DS E ++ C
Sbjct: 1803 GDCIN---------------------------------QEPKDSSPAEECDD-------C 1822
Query: 267 DKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYA 326
D CV L + L + KS + +S+ A + + L+ +L + +
Sbjct: 1823 DSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAIS 1882
Query: 327 LRKIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRD 386
+I E + L + E L EK SRK Q + N+ ++ + A ++
Sbjct: 1883 NHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN-------NNVNRATQSAKELDV 1935
Query: 387 KIQEINNKMLYY--------GEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDE 438
KI+ + + GE + + + S + AQ+M+ E+R+R + L +
Sbjct: 1936 KIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRN---FGKHLREA 1992
Query: 439 EAD--EAYELLSQAESWQRLH-NETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDA 495
EAD E+ LL++ +WQ+ H E L + + L++Y AKLSDL+ L +A + A
Sbjct: 1993 EADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQA 2052
Query: 496 EDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIY 555
+N+ ++Q + + L+T+ SL + L ++ K +
Sbjct: 2053 NGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLA 2112
Query: 556 AEIDGAKSELQVKLSNLSNLS--HDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKA 613
A ++ A+ EL K+ LS + LV+EA HA+ LQ+ A +L ++ + LV+ A
Sbjct: 2113 ASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCA 2172
Query: 614 LDASNVYENIVNYVSEANETAEFALNTTDRIYDAV--SGIDTQIIYHKDESENLLNQARE 671
+DA+ YENI+N + A + A A + ++ V + + S+ LLN+A+
Sbjct: 2173 VDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKM 2232
Query: 672 LQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLIT 731
Q K + A+ + + + +K + T L+ L +RGD + ++ +
Sbjct: 2233 TQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMV 2292
Query: 732 EEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQ 791
+AN T EV P+ ++ + + A+ A ++V LT +P L +
Sbjct: 2293 RKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRK 2352
Query: 792 LRTVEQK-RPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKA 850
+ ++ Q+ P N+S ++ RIRELI Q R ASK+ V M F+G+S VEV ++DLK
Sbjct: 2353 IESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKG 2412
Query: 851 FTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEI 910
+TSLSL+++ P R E T + F++YLG+K+A ++Y+G+A+ + L VYNLG ++ E+
Sbjct: 2413 YTSLSLFLQRPNSR-ENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAEL 2471
Query: 911 PLDSKPVSS--WPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDL 968
+D S A VK +R+ + ++ T + SS E + + ++LL+L
Sbjct: 2472 QVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNL 2531
Query: 969 DPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPC 1028
DPE+ VFYVGG P +FKLP+ L+ P + GC+EL LN +V+SLYNFK +N++ + PC
Sbjct: 2532 DPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPC 2591
Query: 1029 ARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGS 1088
R K + +F+G+GYA V + F ++T D GL+ NG
Sbjct: 2592 RRRK-----EESDKNYFEGTGYARV----PTQPHAPIPTFGQTIQTTVDRGLLFFAENGD 2642
Query: 1089 MFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQ-----INDAKYHEISI-IYHNDKKM 1142
F L + +G L V Y L L K + IN+ + H I I I K+M
Sbjct: 2643 RFISLNIEDGKLMVRY---------KLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRM 2693
Query: 1143 ILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQK 1202
+ VD ++ +D E F+ Y+GG P I + + FRGCMK K
Sbjct: 2694 WINVDVQNT-IIDGE--VFDFSTYYLGGIPIAIRERFNISTPA-----FRGCMKNL---K 2742
Query: 1203 KDFNLLEQTETLGVGYGCPEDSLISRRAYFN-GQSFIASIQKISFFDGFEGGFNFRTLQP 1261
K ++ +T+GV C ED + R A F+ G + + D + F F+T QP
Sbjct: 2743 KTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQP 2802
Query: 1262 NGLLFYYASGSDVFSISLDNGTVIMDV--KGIKVQSVDKQYNDGLSHFVISSVSPTRYEL 1319
+G+L + + + ++L++G + + G + + Y DGL H+V + L
Sbjct: 2803 SGILLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRL 2862
Query: 1320 IVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVE 1379
++D + + +++ +S + GGS NF GCISN + R+ EV
Sbjct: 2863 LIDDQLLRNSK----RLKHISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEVL 2911
Query: 1380 DFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKL 1439
D + K SL C + P +L K +K K + + +D P P ++K+
Sbjct: 2912 DLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKV 2969
Query: 1440 PERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHG 1499
+ C +A A Q+G S F+ + +SQF++ ++T SS G
Sbjct: 2970 WQ------DACSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRG 3023
Query: 1500 MIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGR 1559
++F+ +N FM L+L+ GRLV+ KKL+I+S+EK NDG WH V+F + GR
Sbjct: 3024 LVFHTG--TKNSFMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGR 3081
Query: 1560 LVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGA 1619
LV+DGLR E SL P +T I+ P+YLG GK K++ N SF GCL N QL+
Sbjct: 3082 LVVDGLRAREGSL-PGNSTISIRAPVYLGSPPSGKP-KSLPTN---SFVGCLKNFQLDSK 3136
Query: 1620 SITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLV 1679
+ + S +F V+ C GP+E G YFS EGG+VVL S +G +F++ F +RPRS +G L+
Sbjct: 3137 PLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILI 3196
Query: 1680 HGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLD 1739
H S G++L V+++ G+V +++G STSVTPKQSLCDG+WH + V +++ L+
Sbjct: 3197 HIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLE 3256
Query: 1740 VDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFS 1799
+D++ ++ G + P +EP+ +GG P +L T R+ K F GC+R+ ++ PV +
Sbjct: 3257 LDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVT 3316
Query: 1800 KAALVSGAVSINSCP 1814
+A V G VS+N CP
Sbjct: 3317 EALEVQGPVSLNGCP 3331
Score = 107 bits (268), Expect = 8e-23
Identities = 73/237 (30%), Positives = 99/237 (41%), Gaps = 58/237 (24%)
Query: 76 SGECVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGY 117
S EC C+C+G+++ C G G C++CQ NT G +CE+C GY
Sbjct: 350 SHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGY 409
Query: 118 I---GDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
G + AP C PC C H A+ C + G+ RC C N+ G NCE+CA GYY
Sbjct: 410 YRPYGVPV-DAPDGCIPCSCDPEH----ADGC--EQGSGRCHCKPNFHGDNCEKCAIGYY 462
Query: 175 GNPLL----------------IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTG 218
P + K CDC+ ++ E CD G+C C G
Sbjct: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLE---GVLPEICD-AHGRCL-CRPGVEG 517
Query: 219 FKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGCDKCV 270
+C+ C G+Y C C C PC SVTG+C CD+C+
Sbjct: 518 PRCDTCRSGFYS----FPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCL 570
Score = 80.9 bits (198), Expect = 1e-14
Identities = 74/246 (30%), Positives = 100/246 (40%), Gaps = 66/246 (26%)
Query: 74 TLSGECVPCDCNGNSNECLDGSG---YCVHCQRNTTGEHCEKCLDGYIGDSIRGA----P 126
++ G+CV CNG++ C + + CQ +T GE C++C GY R A
Sbjct: 294 SIGGQCV---CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQS 350
Query: 127 QFCQPCPCPLPHLANFAESCY-----------------RKNGAVRCICNENYAGPNCERC 169
C+ C C A +CY G V C N AG NCE+C
Sbjct: 351 HECEACNC-----HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQC 405
Query: 170 APGY---YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226
A GY YG P+ C C C DP + C++ +G+C +C N G CE+CA
Sbjct: 406 AKGYYRPYGVPVDAPDGCIPCSC----DPEHA-DGCEQGSGRC-HCKPNFHGDNCEKCAI 459
Query: 227 GYY-----------------GDARIAKNCAVCNC---GGGP--CDSVTGECL-EEGFEPP 263
GYY + +A + C+C G P CD+ G CL G E P
Sbjct: 460 GYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA-HGRCLCRPGVEGP 518
Query: 264 TGCDKC 269
CD C
Sbjct: 519 R-CDTC 523
Score = 71.2 bits (173), Expect = 8e-12
Identities = 70/266 (26%), Positives = 96/266 (36%), Gaps = 30/266 (11%)
Query: 18 SAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSG 77
++A S A A P + + A G PE + + +C G H
Sbjct: 1250 NSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATG--HYGFP 1307
Query: 78 ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKC-LDGYIGDSIRGAPQFCQPCPCPL 136
C PC C C + +G C C T CE C + + G C+ C C
Sbjct: 1308 RCKPCSCGRRL--CEEMTGQC-RCPPRTVRPQCEVCETHSFSFHPMAG----CEGCNCSR 1360
Query: 137 PHLANFA-ESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCS-GNSD 194
A C R +G +C C G C+RCA G+Y P C C+C+ ++
Sbjct: 1361 RGTIEAAMPECDRDSG--QCRCKPRITGRQCDRCASGFYRFP-----ECVPCNCNRDGTE 1413
Query: 195 PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG-YYGDARIAKNCAVCNCGGGPCDSVTG 253
P + CD TG C C N G +C C G ++ D K C C C G V
Sbjct: 1414 PGV----CDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKGCTSCFCFG-----VNN 1463
Query: 254 ECLEEGFEPPTGCDKCVWDLTDALRL 279
+C D W L A R+
Sbjct: 1464 QCHSSHKRRTKFVDMLGWHLETADRV 1489
Score = 70.1 bits (170), Expect = 2e-11
Identities = 57/210 (27%), Positives = 73/210 (34%), Gaps = 59/210 (28%)
Query: 105 TTGEHCEKCLDGYIGDSIRGA-PQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAG 163
T C+ + +GA P C P PH C + G +C C N G
Sbjct: 1243 TASRFCKNSARSLVAFYHKGALPCECHPTGATGPH-------CSPEGG--QCPCQPNVIG 1293
Query: 164 PNCERCAPGYYG----NPLLIG-----------------------------------STC 184
C RCA G+YG P G + C
Sbjct: 1294 RQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGC 1353
Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244
+ C+CS +CD +GQCR C TG +C+RCA G+Y C CNC
Sbjct: 1354 EGCNCSRRGTIEAAMPECDRDSGQCR-CKPRITGRQCDRCASGFYR----FPECVPCNCN 1408
Query: 245 -----GGPCDSVTGECLEEGFEPPTGCDKC 269
G CD TG CL + T C+ C
Sbjct: 1409 RDGTEPGVCDPGTGACLCKENVEGTECNVC 1438
Score = 63.5 bits (153), Expect = 2e-09
Identities = 52/210 (24%), Positives = 77/210 (36%), Gaps = 24/210 (11%)
Query: 62 PAAEKCNAGFFHTLSGECVPCDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDG-YIG 119
P + C +GF+ + C G+ C +G C C+ TG+ C++CL G Y
Sbjct: 518 PRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDF 576
Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
+G+ C P +L C C + GP C RC Y+
Sbjct: 577 PHCQGSSSACDPAGTINSNLGY-------------CQCKLHVEGPTCSRCKLLYWNLDKE 623
Query: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCA 239
S C +C C + E C + G C +C + G C+ C GY+ +
Sbjct: 624 NPSGCSECKCHKAGTVSGTGE-CRQGDGDC-HCKSHVGGDSCDTCEDGYFA----LEKSN 677
Query: 240 VCNCGGGPCDSVTGECLEEGFEPPTGCDKC 269
C G CD G L P+G +C
Sbjct: 678 YFGCQGCQCD--IGGALSSMCSGPSGVCQC 705
Score = 51.6 bits (122), Expect = 7e-06
Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 13/102 (12%)
Query: 79 CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF-CQPC 132
C C C+ + EC G G C HC+ + G+ C+ C DGY ++ + F CQ C
Sbjct: 628 CSECKCHKAGTVSGTGECRQGDGDC-HCKSHVGGDSCDTCEDGYF--ALEKSNYFGCQGC 684
Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
C + + C +G C C E+ G C+R YY
Sbjct: 685 QCDIG--GALSSMCSGPSGV--CQCREHVVGKVCQRPENNYY 722
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 804 bits (2076), Expect = 0.0
Identities = 547/1805 (30%), Positives = 870/1805 (48%), Gaps = 191/1805 (10%)
Query: 40 SAVGRQDPPETSEPRVALG----RLPPA-----AEKCNAGFFHT----LSGECVPCDCNG 86
S VG ++ +T R+AL PPA + C+ G++ +G CVPC+CNG
Sbjct: 1632 SEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNG 1691
Query: 87 NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESC 146
+SN+C DGSG CV+CQ NT GEHCE+C +GY G+++ G+ C+ CPC PH +FA C
Sbjct: 1692 HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS---CRACPC--PHTNSFATGC 1746
Query: 147 YRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVT 206
G VRC C Y G CERCAPGY+GNP G +C+ C C+ N C +T
Sbjct: 1747 VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLT 1802
Query: 207 GQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGC 266
G C N P DS E ++ C
Sbjct: 1803 GDCIN---------------------------------QEPKDSSPAEECDD-------C 1822
Query: 267 DKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYA 326
D CV L + L + KS + +S+ A + + L+ +L + +
Sbjct: 1823 DSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAIS 1882
Query: 327 LRKIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRD 386
+I E + L + E L EK SRK Q + + +N A+Q
Sbjct: 1883 NHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLN----NNVNRATQ---------- 1928
Query: 387 KIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYEL 446
S KE+ K+ + ++ + +
Sbjct: 1929 ------------------SAKELDVKI---KNVIRNV---------------------HM 1946
Query: 447 LSQAESWQRLH-NETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAAR 505
L++ +WQ+ H E L + + L++Y AKLSDL+ L +A + A +N+
Sbjct: 1947 LNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERA 2006
Query: 506 QRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSEL 565
++Q + + L+T+ SL + L ++ K + A ++ A+ EL
Sbjct: 2007 LGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQEL 2066
Query: 566 QVKLSNLSNLS--HDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENI 623
K+ LS + LV+EA HA+ LQ+ A +L ++ + LV+ A+DA+ YENI
Sbjct: 2067 SDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENI 2126
Query: 624 VNYVSEANETAEFALNTTDRIYDAV--SGIDTQIIYHKDESENLLNQARELQAKAESSSD 681
+N + A + A A + ++ V + + S+ LLN+A+ Q K +
Sbjct: 2127 LNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVS 2186
Query: 682 EAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEV 741
A+ + + + +K + T L+ L +RGD + ++ + +AN T EV
Sbjct: 2187 PALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEV 2246
Query: 742 QQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQK-RP 800
P+ ++ + + A+ A ++V LT +P L ++ ++ Q+ P
Sbjct: 2247 LDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLP 2306
Query: 801 ASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKP 860
N+S ++ RIRELI Q R ASK+ V M F+G+S VEV ++DLK +TSLSL+++
Sbjct: 2307 LGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQR 2366
Query: 861 PVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSS- 919
P R E T + F++YLG+K+A ++Y+G+A+ + L VYNLG ++ E+ +D S
Sbjct: 2367 PNSR-ENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSE 2425
Query: 920 -WPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVG 978
A VK +R+ + ++ T + SS E + + ++LL+LDPE+ VFYVG
Sbjct: 2426 TKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVG 2485
Query: 979 GVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQS 1038
G P +FKLP+ L+ P + GC+EL LN +V+SLYNFK +N++ + PC R K
Sbjct: 2486 GYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRK-----E 2540
Query: 1039 RAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNG 1098
+ +F+G+GYA V + F ++T D GL+ NG F L + +G
Sbjct: 2541 ESDKNYFEGTGYARV----PTQPHAPIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDG 2596
Query: 1099 YLHVFYDFGFSGGPVHLEDTLKKAQ-----INDAKYHEISI-IYHNDKKMILVVDRRHVK 1152
L V Y L L K + IN+ + H I I I K+M + VD ++
Sbjct: 2597 KLMVRY---------KLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNT- 2646
Query: 1153 SMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTE 1212
+D E F+ Y+GG P I + + FRGCMK KK ++ +
Sbjct: 2647 IIDGE--VFDFSTYYLGGIPIAIRERFNISTPA-----FRGCMKNL---KKTSGVVRLND 2696
Query: 1213 TLGVGYGCPEDSLISRRAYFN-GQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASG 1271
T+GV C ED + R A F+ G + + D + F F+T QP+G+L + +
Sbjct: 2697 TVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTW 2756
Query: 1272 SDVFSISLDNGTVIMDV--KGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSK 1329
+ ++L++G + + G + + Y DGL H+V + L++D + +
Sbjct: 2757 TRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNS 2816
Query: 1330 NPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVH 1389
+++ +S + GGS NF GCISN + R+ EV D + K
Sbjct: 2817 K----RLKHISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEVLDLTSNSLKRD 2865
Query: 1390 TSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSH 1449
SL C + P +L K +K K + + +D P P ++K+ +
Sbjct: 2866 VSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKVWQ------DA 2917
Query: 1450 CHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEE 1509
C +A A Q+G S F+ + +SQF++ ++T SS G++F+ +
Sbjct: 2918 CSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTG--TK 2975
Query: 1510 NDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLE 1569
N FM L+L+ GRLV+ KKL+I+S+EK NDG WH V+F + GRLV+DGLR E
Sbjct: 2976 NSFMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRARE 3035
Query: 1570 ESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFS 1629
SL P +T I+ P+YLG GK K++ N SF GCL N QL+ + + S +F
Sbjct: 3036 GSL-PGNSTISIRAPVYLGSPPSGKP-KSLPTN---SFVGCLKNFQLDSKPLYTPSSSFG 3090
Query: 1630 VTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYL 1689
V+ C GP+E G YFS EGG+VVL S +G +F++ F +RPRS +G L+H S G++L
Sbjct: 3091 VSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHL 3150
Query: 1690 NVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVG 1749
V+++ G+V +++G STSVTPKQSLCDG+WH + V +++ L++D++ ++ G
Sbjct: 3151 CVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAG 3210
Query: 1750 PLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVS 1809
+ P +EP+ +GG P +L T R+ K F GC+R+ ++ PV ++A V G VS
Sbjct: 3211 QIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVS 3270
Query: 1810 INSCP 1814
+N CP
Sbjct: 3271 LNGCP 3275
Score = 107 bits (268), Expect = 8e-23
Identities = 73/237 (30%), Positives = 99/237 (41%), Gaps = 58/237 (24%)
Query: 76 SGECVPCDCNGNSNECL------------------DGSGYCVHCQRNTTGEHCEKCLDGY 117
S EC C+C+G+++ C G G C++CQ NT G +CE+C GY
Sbjct: 350 SHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGY 409
Query: 118 I---GDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
G + AP C PC C H A+ C + G+ RC C N+ G NCE+CA GYY
Sbjct: 410 YRPYGVPV-DAPDGCIPCSCDPEH----ADGC--EQGSGRCHCKPNFHGDNCEKCAIGYY 462
Query: 175 GNPLL----------------IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTG 218
P + K CDC+ ++ E CD G+C C G
Sbjct: 463 NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLE---GVLPEICD-AHGRCL-CRPGVEG 517
Query: 219 FKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGCDKCV 270
+C+ C G+Y C C C PC SVTG+C CD+C+
Sbjct: 518 PRCDTCRSGFYS----FPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCL 570
Score = 80.9 bits (198), Expect = 1e-14
Identities = 74/246 (30%), Positives = 100/246 (40%), Gaps = 66/246 (26%)
Query: 74 TLSGECVPCDCNGNSNECLDGSG---YCVHCQRNTTGEHCEKCLDGYIGDSIRGA----P 126
++ G+CV CNG++ C + + CQ +T GE C++C GY R A
Sbjct: 294 SIGGQCV---CNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQS 350
Query: 127 QFCQPCPCPLPHLANFAESCY-----------------RKNGAVRCICNENYAGPNCERC 169
C+ C C A +CY G V C N AG NCE+C
Sbjct: 351 HECEACNC-----HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQC 405
Query: 170 APGY---YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226
A GY YG P+ C C C DP + C++ +G+C +C N G CE+CA
Sbjct: 406 AKGYYRPYGVPVDAPDGCIPCSC----DPEHA-DGCEQGSGRC-HCKPNFHGDNCEKCAI 459
Query: 227 GYY-----------------GDARIAKNCAVCNC---GGGP--CDSVTGECL-EEGFEPP 263
GYY + +A + C+C G P CD+ G CL G E P
Sbjct: 460 GYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDA-HGRCLCRPGVEGP 518
Query: 264 TGCDKC 269
CD C
Sbjct: 519 R-CDTC 523
Score = 71.2 bits (173), Expect = 8e-12
Identities = 70/266 (26%), Positives = 96/266 (36%), Gaps = 30/266 (11%)
Query: 18 SAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSG 77
++A S A A P + + A G PE + + +C G H
Sbjct: 1250 NSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATG--HYGFP 1307
Query: 78 ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKC-LDGYIGDSIRGAPQFCQPCPCPL 136
C PC C C + +G C C T CE C + + G C+ C C
Sbjct: 1308 RCKPCSCGRRL--CEEMTGQC-RCPPRTVRPQCEVCETHSFSFHPMAG----CEGCNCSR 1360
Query: 137 PHLANFA-ESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCS-GNSD 194
A C R +G +C C G C+RCA G+Y P C C+C+ ++
Sbjct: 1361 RGTIEAAMPECDRDSG--QCRCKPRITGRQCDRCASGFYRFP-----ECVPCNCNRDGTE 1413
Query: 195 PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG-YYGDARIAKNCAVCNCGGGPCDSVTG 253
P + CD TG C C N G +C C G ++ D K C C C G V
Sbjct: 1414 PGV----CDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKGCTSCFCFG-----VNN 1463
Query: 254 ECLEEGFEPPTGCDKCVWDLTDALRL 279
+C D W L A R+
Sbjct: 1464 QCHSSHKRRTKFVDMLGWHLETADRV 1489
Score = 70.1 bits (170), Expect = 2e-11
Identities = 57/210 (27%), Positives = 73/210 (34%), Gaps = 59/210 (28%)
Query: 105 TTGEHCEKCLDGYIGDSIRGA-PQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAG 163
T C+ + +GA P C P PH C + G +C C N G
Sbjct: 1243 TASRFCKNSARSLVAFYHKGALPCECHPTGATGPH-------CSPEGG--QCPCQPNVIG 1293
Query: 164 PNCERCAPGYYG----NPLLIG-----------------------------------STC 184
C RCA G+YG P G + C
Sbjct: 1294 RQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGC 1353
Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244
+ C+CS +CD +GQCR C TG +C+RCA G+Y C CNC
Sbjct: 1354 EGCNCSRRGTIEAAMPECDRDSGQCR-CKPRITGRQCDRCASGFYR----FPECVPCNCN 1408
Query: 245 -----GGPCDSVTGECLEEGFEPPTGCDKC 269
G CD TG CL + T C+ C
Sbjct: 1409 RDGTEPGVCDPGTGACLCKENVEGTECNVC 1438
Score = 63.5 bits (153), Expect = 2e-09
Identities = 52/210 (24%), Positives = 77/210 (36%), Gaps = 24/210 (11%)
Query: 62 PAAEKCNAGFFHTLSGECVPCDCNGNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDG-YIG 119
P + C +GF+ + C G+ C +G C C+ TG+ C++CL G Y
Sbjct: 518 PRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDF 576
Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
+G+ C P +L C C + GP C RC Y+
Sbjct: 577 PHCQGSSSACDPAGTINSNLGY-------------CQCKLHVEGPTCSRCKLLYWNLDKE 623
Query: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCA 239
S C +C C + E C + G C +C + G C+ C GY+ +
Sbjct: 624 NPSGCSECKCHKAGTVSGTGE-CRQGDGDC-HCKSHVGGDSCDTCEDGYFA----LEKSN 677
Query: 240 VCNCGGGPCDSVTGECLEEGFEPPTGCDKC 269
C G CD G L P+G +C
Sbjct: 678 YFGCQGCQCD--IGGALSSMCSGPSGVCQC 705
Score = 51.6 bits (122), Expect = 7e-06
Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 13/102 (12%)
Query: 79 CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF-CQPC 132
C C C+ + EC G G C HC+ + G+ C+ C DGY ++ + F CQ C
Sbjct: 628 CSECKCHKAGTVSGTGECRQGDGDC-HCKSHVGGDSCDTCEDGYF--ALEKSNYFGCQGC 684
Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
C + + C +G C C E+ G C+R YY
Sbjct: 685 QCDIG--GALSSMCSGPSGV--CQCREHVVGKVCQRPENNYY 722
>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
Length = 1668
Score = 799 bits (2063), Expect = 0.0
Identities = 541/1789 (30%), Positives = 864/1789 (48%), Gaps = 183/1789 (10%)
Query: 47 PPETSEPRVALGRLPPAAEKCNAGFFHT----LSGECVPCDCNGNSNECLDGSGYCVHCQ 102
PP S+ + + P+ + C+ G++ +G CVPC+CNG+SN+C DGSG CV+CQ
Sbjct: 40 PPGQSQLQASYVEFRPS-QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQ 98
Query: 103 RNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYA 162
NT GEHCE+C +GY G+++ G+ C+ CPC PH +FA C G VRC C Y
Sbjct: 99 HNTAGEHCERCQEGYYGNAVHGS---CRACPC--PHTNSFATGCVVNGGDVRCSCKAGYT 153
Query: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCE 222
G CERCAPGY+GNP G +C+ C C+ N C +TG C N
Sbjct: 154 GTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLTGDCIN----------- 198
Query: 223 RCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAAL 282
P DS E ++ CD CV L + L
Sbjct: 199 ----------------------QEPKDSSPAEECDD-------CDSCVMTLLNDLATMGE 229
Query: 283 SIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSL 342
+ KS + +S+ A + + L+ +L + + +I E + L
Sbjct: 230 QLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDL 289
Query: 343 LSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEH 402
+ E L EK SRK Q + + +N A+Q
Sbjct: 290 NQEFETLQEKAQVNSRKAQTLN----NNVNRATQ-------------------------- 319
Query: 403 ELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLH-NETR 461
S KE+ K+ + ++ + +L++ +WQ+ H E
Sbjct: 320 --SAKELDVKI---KNVIRNV---------------------HMLNRIRTWQKTHQGENN 353
Query: 462 TLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQME 521
L + + L++Y AKLSDL+ L +A + A +N+ ++Q + +
Sbjct: 354 GLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQS 413
Query: 522 VVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLS--HDL 579
L+T+ SL + L ++ K + A ++ A+ EL K+ LS + L
Sbjct: 414 DFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSL 473
Query: 580 VQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALN 639
V+EA HA+ LQ+ A +L ++ + LV+ A+DA+ YENI+N + A + A A +
Sbjct: 474 VEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAAS 533
Query: 640 TTDRIYDAV--SGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALAR 697
++ V + + S+ LLN+A+ Q K + A+ + + + +
Sbjct: 534 ASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQ 593
Query: 698 KSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQ 757
K + T L+ L +RGD + ++ + +AN T EV P+ ++
Sbjct: 594 KEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKD 653
Query: 758 NLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQK-RPASNVSASIQRIRELIA 816
+ + A+ A ++V LT +P L ++ ++ Q+ P N+S ++ RIRELI
Sbjct: 654 TYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQ 713
Query: 817 QTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFIL 876
Q R ASK+ V M F+G+S VEV ++DLK +TSLSL+++ P R E T + F++
Sbjct: 714 QARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSR-ENGGTENMFVM 772
Query: 877 YLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSS--WPAYFSIVKIERVGK 934
YLG+K+A ++Y+G+A+ + L VYNLG ++ E+ +D S A VK +R+ +
Sbjct: 773 YLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQ 832
Query: 935 HGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPG 994
++ T + SS E + + ++LL+LDPE+ VFYVGG P +FKLP+ L+ P
Sbjct: 833 FARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPP 892
Query: 995 FVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVR 1054
+ GC+EL LN +V+SLYNFK +N++ + PC R K + +F+G+GYA V
Sbjct: 893 YKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRK-----EESDKNYFEGTGYARV- 946
Query: 1055 DITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVH 1114
+ F ++T D GL+ NG F L + +G L V Y
Sbjct: 947 ---PTQPHAPIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVRY---------K 994
Query: 1115 LEDTLKKAQ-----INDAKYHEISI-IYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYI 1168
L L K + IN+ + H I I I K+M + VD ++ +D E F+ Y+
Sbjct: 995 LNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNT-IIDGE--VFDFSTYYL 1051
Query: 1169 GGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISR 1228
GG P I + + FRGCMK KK ++ +T+GV C ED + R
Sbjct: 1052 GGIPIAIRERFNISTPA-----FRGCMKNL---KKTSGVVRLNDTVGVTKKCSEDWKLVR 1103
Query: 1229 RAYFN-GQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMD 1287
A F+ G + + D + F F+T QP+G+L + + + ++L++G + +
Sbjct: 1104 SASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTLEDGYIELS 1163
Query: 1288 V--KGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKK 1345
G + + Y DGL H+V + L++D + + +++ +S +
Sbjct: 1164 TSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSK----RLKHISSSRQS 1219
Query: 1346 FYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLL 1405
GGS NF GCISN + R+ EV D + K SL C + P +L
Sbjct: 1220 LRLGGS-------NFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLML 1272
Query: 1406 HKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQY 1465
K +K K + + +D P P ++K+ + C +A A Q+
Sbjct: 1273 LKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKVWQ------DACSPLPKTQANHGALQF 1324
Query: 1466 GGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYM 1525
G S F+ + +SQF++ ++T SS G++F+ +N FM L+L+ GRLV+
Sbjct: 1325 GDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTG--TKNSFMALYLSKGRLVFA 1382
Query: 1526 FNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPI 1585
KKL+I+S+EK NDG WH V+F + GRLV+DGLR E SL P +T I+ P+
Sbjct: 1383 LGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSL-PGNSTISIRAPV 1441
Query: 1586 YLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFS 1645
YLG GK K++ N SF GCL N QL+ + + S +F V+ C GP+E G YFS
Sbjct: 1442 YLGSPPSGKP-KSLPTN---SFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFS 1497
Query: 1646 TEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNG 1705
EGG+VVL S +G +F++ F +RPRS +G L+H S G++L V+++ G+V +++G
Sbjct: 1498 EEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSG 1557
Query: 1706 IRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVG 1765
STSVTPKQSLCDG+WH + V +++ L++D++ ++ G + P +EP+ +G
Sbjct: 1558 AGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLG 1617
Query: 1766 GVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSCP 1814
G P +L T R+ K F GC+R+ ++ PV ++A V G VS+N CP
Sbjct: 1618 GAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCP 1666
>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
Length = 1724
Score = 755 bits (1949), Expect = 0.0
Identities = 538/1801 (29%), Positives = 870/1801 (48%), Gaps = 125/1801 (6%)
Query: 60 LPPAAEK--CNAGF---FHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCL 114
+PPA + C+ G+ F G+C+ L G + C
Sbjct: 1 MPPAVRRSACSMGWLWIFGAALGQCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCS 60
Query: 115 DGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGY 173
GY D C PC C + C ++G+ C+ C N AG +CERC GY
Sbjct: 61 PGYYRDHKGLYTGRCVPCNCN-----GHSNQC--QDGSGICVNCQHNTAGEHCERCQEGY 113
Query: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCR-NCLRNTTGFKCERCAPGYYGDA 232
YGN + +C+ C C N C G R +C TG +CERCAPGY+G+
Sbjct: 114 YGNA--VHGSCRACPCPHT---NSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 168
Query: 233 -RIAKNCAVCNCGG----GPCDSVTGECLEEG------FEPPTGCDKCVWDLTDALRLAA 281
+ +C C+C G C +TG+C+ + E CD CV L + L
Sbjct: 169 QKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMG 228
Query: 282 LSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKS 341
+ KS + +S+ A + + L+ +L + + +I E +
Sbjct: 229 EQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTD 288
Query: 342 LLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYY--- 398
L + E L EK SRK Q + N+ ++ + A ++ KI+ + +
Sbjct: 289 LNQEFETLQEKAQVNSRKAQTLN-------NNVNRATQSAKELDVKIKNVIRNVHILLKQ 341
Query: 399 -----GEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEAD--EAYELLSQAE 451
GE + + + S + AQ+M+ E+R+R + L + EAD E+ LL++
Sbjct: 342 ISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRN---FGKHLREAEADKRESQLLLNRIR 398
Query: 452 SWQRLHN-ETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHE 510
+WQ+ H E L + + L++Y AKLSDL+ L +A + A +N+ +
Sbjct: 399 TWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQ 458
Query: 511 KQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLS 570
+Q + + L+T+ SL + L ++ K + A ++ A+ EL K+
Sbjct: 459 RQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVR 518
Query: 571 NLSNLSH--DLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVS 628
LS + LV+EA HA+ LQ+ A +L ++ + LV+ A+DA+ YENI+N +
Sbjct: 519 ELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIK 578
Query: 629 EANETAEFALNTTDRIYDAV--SGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVAD 686
A + A A + ++ V + + S+ LLN+A+ Q K + A+ +
Sbjct: 579 AAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNN 638
Query: 687 TSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATA 746
+ + +K + T L+ L +RGD + ++ + +AN T EV
Sbjct: 639 LQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLN 698
Query: 747 PMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKR-PASNVS 805
P+ ++ + + A+ A ++V LT +P L ++ ++ Q+ P N+S
Sbjct: 699 PIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNIS 758
Query: 806 ASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRP 865
++ RIRELI Q R ASK+ V M F+G+S VEV ++DLK +TSLSL+++ P R
Sbjct: 759 DNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSR- 817
Query: 866 ELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWP--AY 923
E T + F++YLG+K+A ++Y+G+A+ + L VYNLG ++ E+ +D S A
Sbjct: 818 ENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAV 877
Query: 924 FSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSN 983
VK +R+ + ++ T + SS E + + ++LL+LDPE+ VFYVGG P +
Sbjct: 878 MDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPD 937
Query: 984 FKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASY 1043
FKLP+ L+ P + GC+EL LN +V+SLYNFK +N++ + PC R K +
Sbjct: 938 FKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRK-----EESDKN 992
Query: 1044 FFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVF 1103
+F+G+GYA V + F ++T D GL+ NG F L + +G L V
Sbjct: 993 YFEGTGYARVPTQPH----APIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVR 1048
Query: 1104 YDFGFSGGPVHLEDTLKKAQ-----INDAKYHEISI-IYHNDKKMILVVDRRHVKSMDNE 1157
Y L L K + IN+ + H I I I K+M + VD ++ +D E
Sbjct: 1049 YK---------LNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNT-IIDGE 1098
Query: 1158 KMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVG 1217
F+ Y+GG P I + + FRGCMK KK ++ +T+GV
Sbjct: 1099 VFD--FSTYYLGGIPIAIRERFNISTPA-----FRGCMKNL---KKTSGVVRLNDTVGVT 1148
Query: 1218 YGCPEDSLISRRAYFN--GQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDVF 1275
C ED + R A F+ GQ + + D + F F+T QP+G+L + + +
Sbjct: 1149 KKCSEDWKLVRSASFSRGGQLSFTDLG-LPPTDHLQASFGFQTFQPSGILLDHQTWTRNL 1207
Query: 1276 SISLDNGTVIMDVK--GIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTK 1333
++L++G + + G + + Y DGL H+V + L++D + +
Sbjct: 1208 QVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSK--- 1264
Query: 1334 GKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLY 1393
+++ +S + GGS NF GCISN + R+ EV D + K SL
Sbjct: 1265 -RLKHISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLG 1316
Query: 1394 ECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHLS 1453
C + P +L K +K K + + +D P P ++K+ + C
Sbjct: 1317 GCSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKVWQ------DACSPL 1368
Query: 1454 NSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFM 1513
+A A Q+G S F+ + +SQF++ ++T SS G++F+ + N FM
Sbjct: 1369 PKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTK--NSFM 1426
Query: 1514 TLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLP 1573
L+L+ GRLV+ KKL+I+S+EK NDG WH V+F + GRLV+DGLR E SLP
Sbjct: 1427 ALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLP 1486
Query: 1574 PTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPC 1633
+T I+ P+YLG GK K++ NS F GCL N QL+ + + S +F V+ C
Sbjct: 1487 GN-STISIRAPVYLGSPPSGKP-KSLPTNS---FVGCLKNFQLDSKPLYTPSSSFGVSSC 1541
Query: 1634 FEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHM 1693
GP+E G YFS EGG+VVL S +G +F++ F +RPRS +G L+H S G++L V++
Sbjct: 1542 LGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYL 1601
Query: 1694 KNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNP 1753
+ G+V +++G STSVTPKQSLCDG+WH + V +++ L++D++ ++ G +
Sbjct: 1602 EAGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPF 1661
Query: 1754 KPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSC 1813
P +EP+ +GG P +L T R+ K F GC+R+ ++ PV ++A V G VS+N C
Sbjct: 1662 PPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGC 1721
Query: 1814 P 1814
P
Sbjct: 1722 P 1722
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 687 bits (1772), Expect = 0.0
Identities = 532/1925 (27%), Positives = 879/1925 (45%), Gaps = 241/1925 (12%)
Query: 63 AAEKCNAGFFHTLSG----ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYI 118
+ ++C GF+ + G CVPC C+G+S+ CL GSG CV CQ NT G HCE+C G++
Sbjct: 1841 SCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFV 1900
Query: 119 GDSIRGAPQF-CQPCPCPLPHLAN-FAESCYRKNGAVR---------------------- 154
S R P C CPCPL +N FAE C + G +
Sbjct: 1901 --SSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGN 1958
Query: 155 ----------CICNEN-----------------------YAGPNCERCAPGYYGNPLLIG 181
C C+ N GP CE CAPG+YGN LL G
Sbjct: 1959 PLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPG 2018
Query: 182 STCKKCDC-----------SGNS--------------------------------DPNLI 198
+ C +CDC SG+ P
Sbjct: 2019 N-CTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAE 2077
Query: 199 FEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGEC--- 255
+C +GQC +C T G +C CAPGY+G + C C C GG CD TG C
Sbjct: 2078 GSECHPQSGQC-HCRPGTMGPQCRECAPGYWGLPE--QGCRRCQCPGGRCDPHTGRCNCP 2134
Query: 256 ------------LEEGFEPPTG----------CDKCVWDLTDALRLAALSIEEGKSGVLS 293
+ P G CD CV L D L A + +
Sbjct: 2135 PGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHCVVLLLDDLERAGALLPAIHEQLRG 2194
Query: 294 VSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEEL---- 349
+++ + A ++ +NA+I L+++L Q+ E SL D L
Sbjct: 2195 INASSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQDARRLGGQA 2254
Query: 350 VEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSP--K 407
V +QAS+ L E+ T+ HA L+ + + E+ ++ + G + +P +
Sbjct: 2255 VGTRDQASQL--LAGTEA--TLGHAKTLLAAIRAVDRTLSELMSQTGHLGLANASAPSGE 2310
Query: 408 EISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQA-ESWQRLHNETRTLFPV 466
++ L +++L E+R+R + + E A LL++ E L E + L
Sbjct: 2311 QLLRTLAEVERLLWEMRARD-LGAPQAAAEAELAAAQRLLARVQEQLSSLWEENQALATQ 2369
Query: 467 VLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMS 526
++L + A L DL+EAL++A++ R+A+++N R + ++++ + + +
Sbjct: 2370 TRDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEALQRKQELSRDNATLQAT 2429
Query: 527 LSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDL--VQEAI 584
L + D+L + L LD + + A +DGA++ L ++ S L V+ A
Sbjct: 2430 LHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFSPAGSKLRLVEAAE 2489
Query: 585 DHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRI 644
HAQ L Q A LS + + + L Q+A++ASN Y I+ V A + A AL D
Sbjct: 2490 AHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQALQQADHT 2549
Query: 645 YDAVSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTR 704
+ V + L+++A++L A + ++ +EA+ +R+G A +T+
Sbjct: 2550 WATVV------------RQGLVDRAQQLLANS-TALEEAMLQEQQRLGLVWAALQGARTQ 2596
Query: 705 LSD-------------AVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANN 751
L D A + + A + + +++ ++ + EA T VQ M N
Sbjct: 2597 LRDVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAAEAQDTATRVQSQLQAMQEN 2656
Query: 752 LTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQK---RPASNVSASI 808
+ W + AV A +V L + +PQLL +L +E + + +SASI
Sbjct: 2657 VERWQGQYEGLRGQDLGQAVLDAGHSVSTLEKTLPQLLAKLSILENRGVHNASLALSASI 2716
Query: 809 QRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELT 868
R+RELIAQ R ASK++V M F+G+S V++ + + DL A+T+L Y++ P P
Sbjct: 2717 GRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYTALKFYLQGPEPEPG-Q 2775
Query: 869 ETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVK 928
T D+F++Y+GS+ A +YMG+++++ + +VY LG + + + F+ V
Sbjct: 2776 GTEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQLGEAGPAVLSIDEDIGE---QFAAVS 2832
Query: 929 IERVGKHGKVFLTVPSLSSTAEEKFIK--KGEF--SGDDSLLDLDPEDTVFYVGGVPSNF 984
++R + G + +TV E + I+ KG+ G + LL+L P+D VFYVGG PS F
Sbjct: 2833 LDRTLQFGHMSVTV-------ERQMIQETKGDTVAPGAEGLLNLRPDDFVFYVGGYPSTF 2885
Query: 985 KLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYF 1044
P L PG+ GC+E+ TLN +V+SLYNF+ + +D + PCAR K +
Sbjct: 2886 TPPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDPWLTDGSY 2945
Query: 1045 FDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFY 1104
DG+G+A I+ + RF+ E+R + +G++ + S F L ++ G L + Y
Sbjct: 2946 LDGTGFA---RISFDSQISTTKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQEGSLVLLY 3002
Query: 1105 DFGF---SGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKI 1161
DFG P+ L A +K ++ ++ + K++++ V+R V S++ +
Sbjct: 3003 DFGAGLKKAVPLQPPPPLTSA----SKAIQVFLLGGSRKRVLVRVERATVYSVEQDNDLE 3058
Query: 1162 PFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYGCP 1221
Y+GG PP+ L +LR P + RGC+KG + K + L++ T GV GC
Sbjct: 3059 LADAYYLGGVPPDQLPP-SLRRLFPTGGSVRGCVKGIKALGKYVD-LKRLNTTGVSAGCT 3116
Query: 1222 EDSLISRRAYFNGQSFI-ASIQKISFFDG-FEGGFNFRTLQPNGLLFYYASGSDVFSISL 1279
D L+ R F+G F+ ++ ++ G GF F + Q + LL+Y AS + +SL
Sbjct: 3117 ADLLVGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYYRASPDGLCQVSL 3176
Query: 1280 DNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQT 1339
G V + + +V++ + DG H+V + T L VD ++ P +G +
Sbjct: 3177 QQGRVSLQLLRTEVKT-QAGFADGAPHYVAFYSNATGVWLYVD-DQLQQMKPHRGPPPEL 3234
Query: 1340 QASEK---KFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECP 1396
Q + + GG P S NF+GCISN + R+ V D Q+ V+ S P
Sbjct: 3235 QPQPEGPPRLLLGGLPESGTIYNFSGCISNVFVQRLLGPQRVFDLQQNLGSVNVSTGCAP 3294
Query: 1397 IESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSP 1456
+ L +G + KAS+ + P+ P + P T R+S
Sbjct: 3295 ALQAQTPGLGPRGLQATARKASRRSR------QPARHPACMLPPHLRTTRDS-------- 3340
Query: 1457 RAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSD-QEENDFMTL 1515
YQ+GG+ +S EF + S+ + RSS G++ + + + + + L
Sbjct: 3341 ------YQFGGSLSSHLEFVGILARHRNWPSLSMHVLPRSSRGLLLFTARLRPGSPSLAL 3394
Query: 1516 FLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPT 1575
FL++G V +L+ +S+++ G WH V E++ LV DG R + P
Sbjct: 3395 FLSNGHFVAQMEGLGTRLRAQSRQRSRPGRWHKVSVRWEKNRILLVTDGARAWSQEGPHR 3454
Query: 1576 E---ATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTP 1632
+ A +++GG+ + + FSGC+ L+L+G + + ++ VTP
Sbjct: 3455 QHQGAEHPQPHTLFVGGLPASSHSSKLPVT--VGFSGCVKRLRLHGRPLGAPTRMAGVTP 3512
Query: 1633 CFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVH-GHSVNGEYLNV 1691
C GP+E G +F GG + LD + EVRP + +G + H G + YL +
Sbjct: 3513 CILGPLEAGLFFPGSGGVITLDLPGATLPDVGLELEVRPLAVTGLIFHLGQARTPPYLQL 3572
Query: 1692 HMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPL 1751
+ QV+++ ++G +FSTSVT LCDG+WHR+ V++ NV++L+VD++ NH VGPL
Sbjct: 3573 QVTEKQVLLRADDGAGEFSTSVTRPSVLCDGQWHRLAVMKSGNVLRLEVDAQSNHTVGPL 3632
Query: 1752 NPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSIN 1811
P+++GG+PE + P+ + GC+R ++ PV+ +++ V GAV +
Sbjct: 3633 LAAAAGAPAPLYLGGLPEPMAVQPWPPA--YCGCMRRLAVNRSPVAMTRSVEVHGAVGAS 3690
Query: 1812 SCPAA 1816
CPAA
Sbjct: 3691 GCPAA 3695
Score = 103 bits (256), Expect = 2e-21
Identities = 71/231 (30%), Positives = 98/231 (42%), Gaps = 46/231 (19%)
Query: 76 SGECVPCDCNGNSNEC--------------LDGS----GYCVHCQRNTTGEHCEKCLDGY 117
+ EC C+C G++ +C LDG+ G C+ CQ +TTG +CE+CL G+
Sbjct: 353 ANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGF 412
Query: 118 IGDSIR--GAPQFCQPCPCPLPHLANFAE-SCYRKNGAVRCICNENYAGPNCERCAPGYY 174
+P C+ C C ++F + +C G RC C N++G C+ CA G+
Sbjct: 413 YRSPNHPLDSPHVCRRCNCE----SDFTDGTCEDLTG--RCYCRPNFSGERCDVCAEGFT 466
Query: 175 GNP---------------LLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGF 219
G P +L CDCS D G+C C N G
Sbjct: 467 GFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRK-DPRVGRCL-CKPNFQGT 524
Query: 220 KCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGEC-LEEGFEPPTGCDKC 269
CE CAPG+YG C+ CD TG+C GFE T CD+C
Sbjct: 525 HCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGAT-CDRC 574
Score = 102 bits (254), Expect = 3e-21
Identities = 73/244 (29%), Positives = 98/244 (40%), Gaps = 42/244 (17%)
Query: 40 SAVGRQDPPETSEPRVALGRLPPA-----AEKCNAGFFHTLSGECVPCDCNGNS---NEC 91
SA G Q +PRV P E C GF+ C PC C+ + C
Sbjct: 497 SAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFY---GPGCQPCQCSSPGVADDRC 553
Query: 92 LDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNG 151
+G C C+ G C++C GY + CQ C C E C +
Sbjct: 554 DPDTGQC-RCRVGFEGATCDRCAPGYFHFPL------CQLCGCS--PAGTLPEGC---DE 601
Query: 152 AVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRN 211
A RC+C +AGP+C+RC PGY+G P C+ C C DP + G CR
Sbjct: 602 AGRCLCQPEFAGPHCDRCRPGYHGFP-----NCQACTC----DPRGALDQLCGAGGLCR- 651
Query: 212 CLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGC 266
C TG C+ C+PG++G +C C+C CD +G+C C
Sbjct: 652 CRPGYTGTACQECSPGFHG----FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRC 707
Query: 267 DKCV 270
D CV
Sbjct: 708 DTCV 711
Score = 100 bits (250), Expect = 1e-20
Identities = 66/198 (33%), Positives = 90/198 (45%), Gaps = 33/198 (16%)
Query: 81 PCDCN---GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
PC C+ C G C C + G C +C GY G P C+PC C
Sbjct: 1437 PCGCHEVGATGPTCEPFGGQCP-CHAHVIGRDCSRCATGYWG-----FPN-CRPCDCG-- 1487
Query: 138 HLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNL 197
A C G +CIC P+C C P +G L+G C++C+CSG L
Sbjct: 1488 -----ARLCDELTG--QCICPPRTIPPDCLLCQPQTFGCHPLVG--CEECNCSGPGIQEL 1538
Query: 198 IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC-----GGGPCDSVT 252
CD +GQC+ C N TG +C+ C+PG++G R C C+C G CD +T
Sbjct: 1539 TDPTCDTDSGQCK-CRPNVTGRRCDTCSPGFHGYPR----CRPCDCHEAGTAPGVCDPLT 1593
Query: 253 GEC-LEEGFEPPTGCDKC 269
G+C +E + P CD+C
Sbjct: 1594 GQCYCKENVQGPK-CDQC 1610
Score = 84.3 bits (207), Expect = 1e-15
Identities = 61/211 (28%), Positives = 85/211 (40%), Gaps = 24/211 (11%)
Query: 63 AAEKCNAGFFHTLSGECVPCDCNGNSN---ECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
A ++C+ GF S CVPC C+ + C SG C C+ TG C+ C+ G
Sbjct: 660 ACQECSPGFHGFPS--CVPCHCSAEGSLHAACDPRSGQC-SCRPRVTGLRCDTCVPGAYN 716
Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLL 179
+C+ C LA + V C+C + GP+C+RC PG++G
Sbjct: 717 FP------YCEAGSCHPAGLAPVDPAL--PEAQVPCMCRAHVEGPSCDRCKPGFWGLSPS 768
Query: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNC 238
C +C C + E C TGQC C + G C C G++G D C
Sbjct: 769 NPEGCTRCSCDLRGTLGGVAE-CQPGTGQC-FCKPHVCGQACASCKDGFFGLDQADYFGC 826
Query: 239 AVCNCGGGPCDSVTGECLEEGFEPPTGCDKC 269
C C G L + EP TG +C
Sbjct: 827 RSCRCD-------IGGALGQSCEPRTGVCRC 850
Score = 83.2 bits (204), Expect = 2e-15
Identities = 55/171 (32%), Positives = 77/171 (45%), Gaps = 23/171 (13%)
Query: 79 CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG-DSIRGAPQFCQPCPCPLP 137
C PCDC C + +G C+ C T C C G + G C+ C C P
Sbjct: 1481 CRPCDCGARL--CDELTGQCI-CPPRTIPPDCLLCQPQTFGCHPLVG----CEECNCSGP 1533
Query: 138 HLANFAE-SCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDC-SGNSDP 195
+ + +C +G +C C N G C+ C+PG++G P C+ CDC + P
Sbjct: 1534 GIQELTDPTCDTDSG--QCKCRPNVTGRRCDTCSPGFHGYP-----RCRPCDCHEAGTAP 1586
Query: 196 NLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCGG 245
+ CD +TGQC C N G KC++C+ G + DA K C C C G
Sbjct: 1587 GV----CDPLTGQCY-CKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFG 1632
Score = 77.0 bits (188), Expect = 2e-13
Identities = 65/250 (26%), Positives = 97/250 (38%), Gaps = 69/250 (27%)
Query: 74 TLSGECVPCDCNGNSNEC-----LDGSGYCVHCQRNTTGEHCEKCLDGYIGD----SIRG 124
++ G CV C+G+++ C D CQ NT G C++C G+ +
Sbjct: 295 SIGGRCV---CHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATAN 351
Query: 125 APQFCQPCPCPLPHLANFAESCY-----------------RKNGAVRCICNENYAGPNCE 167
+ CQ C C A CY + G V C + G NCE
Sbjct: 352 SANECQSCNC-----YGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCE 406
Query: 168 RCAPGYY---GNPLLIGSTCKKCDCSGNSDPNLIFED--CDEVTGQCRNCLRNTTGFKCE 222
RC PG+Y +PL C++C+C + F D C+++TG+C C N +G +C+
Sbjct: 407 RCLPGFYRSPNHPLDSPHVCRRCNCESD------FTDGTCEDLTGRC-YCRPNFSGERCD 459
Query: 223 RCAPGYYG------------DAR---------IAKNCAVCNCGGGPC--DSVTGECLEEG 259
CA G+ G D R + +C+ G C D G CL +
Sbjct: 460 VCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKP 519
Query: 260 FEPPTGCDKC 269
T C+ C
Sbjct: 520 NFQGTHCELC 529
Score = 70.5 bits (171), Expect = 1e-11
Identities = 45/161 (27%), Positives = 66/161 (40%), Gaps = 29/161 (18%)
Query: 143 AESCYRKNGA----VRCICNENYAGPNCERCAPGYYGNP-----LLIGSTCKKCDCSGNS 193
A++C K+ ++C C N G C+RC PG+ P + C+ C+C G++
Sbjct: 306 ADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHA 365
Query: 194 -----DPNL-------IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN---- 237
DP + + + G C +C +TTG CERC PG+Y +
Sbjct: 366 TDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHV 425
Query: 238 CAVCNCGG----GPCDSVTGECLEEGFEPPTGCDKCVWDLT 274
C CNC G C+ +TG C CD C T
Sbjct: 426 CRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFT 466
Score = 65.9 bits (159), Expect = 4e-10
Identities = 46/144 (31%), Positives = 63/144 (43%), Gaps = 22/144 (15%)
Query: 60 LPPAAEKCNAGFF--HTLSGECVPCDCNGNSNE------CLDGSGYCVHCQRNTTGEHCE 111
+PP C F H L G C C+C+G + C SG C C+ N TG C+
Sbjct: 1505 IPPDCLLCQPQTFGCHPLVG-CEECNCSGPGIQELTDPTCDTDSGQC-KCRPNVTGRRCD 1562
Query: 112 KCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAES-CYRKNGAVRCICNENYAGPNCERCA 170
C G+ G P+ C+PC C H A A C G +C C EN GP C++C+
Sbjct: 1563 TCSPGF-----HGYPR-CRPCDC---HEAGTAPGVCDPLTG--QCYCKENVQGPKCDQCS 1611
Query: 171 PGYYGNPLLIGSTCKKCDCSGNSD 194
G + C +C C G ++
Sbjct: 1612 LGTFSLDAANPKGCTRCFCFGATE 1635
Score = 62.8 bits (151), Expect = 3e-09
Identities = 33/92 (35%), Positives = 45/92 (48%), Gaps = 10/92 (10%)
Query: 155 CICNENYAGPNCERCAPGYYGN--PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNC 212
C+C +Y G +C+ CAPG+Y + L +G C C C G+SD C +G C +C
Sbjct: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLG-RCVPCQCHGHSD------RCLPGSGVCVDC 1883
Query: 213 LRNTTGFKCERCAPGYYGDA-RIAKNCAVCNC 243
NT G CERC G+ + C C C
Sbjct: 1884 QHNTEGAHCERCQAGFVSSRDDPSAPCVSCPC 1915
Score = 59.3 bits (142), Expect = 3e-08
Identities = 48/169 (28%), Positives = 69/169 (40%), Gaps = 23/169 (13%)
Query: 21 CSRAASGDDNAFPFDIEGS---SAVGRQDP--PETSEPRVALGRLP-PAAEKCNAGFFHT 74
C G N FP+ GS + + DP PE P + + P+ ++C GF+
Sbjct: 707 CDTCVPGAYN-FPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGL 765
Query: 75 LSGE---CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
C C C+ G EC G+G C C+ + G+ C C DG+ G + A
Sbjct: 766 SPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCF-CKPHVCGQACASCKDGFFG--LDQAD 822
Query: 127 QF-CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
F C+ C C + +SC + G C C N GP C A +Y
Sbjct: 823 YFGCRSCRCDIG--GALGQSCEPRTGV--CRCRPNTQGPTCSEPARDHY 867
Score = 53.5 bits (127), Expect = 2e-06
Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 34/122 (27%)
Query: 178 LLIGSTCKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
L + + C C G + P C+ GQC C + G C RCA GY+G
Sbjct: 1429 LFYNNGARPCGCHEVGATGPT-----CEPFGGQCP-CHAHVIGRDCSRCATGYWG----F 1478
Query: 236 KNCAVCNCGGGPCDSVTGECL----------------EEGFEPPTGCDKC------VWDL 273
NC C+CG CD +TG+C+ G P GC++C + +L
Sbjct: 1479 PNCRPCDCGARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQEL 1538
Query: 274 TD 275
TD
Sbjct: 1539 TD 1540
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 421 bits (1082), Expect = e-117
Identities = 450/1858 (24%), Positives = 778/1858 (41%), Gaps = 219/1858 (11%)
Query: 57 LGRLPPAAEKCNAGFFHTLS-----------GECVPCDCNGNSNECLDGSGYCVHCQRNT 105
LG + E C GF+ S G CVPC CNG+S+ C + C +CQ +T
Sbjct: 1384 LGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHT 1443
Query: 106 TGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLA-NFAESCYRKN-GAVRC-ICNENYA 162
G+ CE+C GY G ++G P CQ C CPL + NF+ SC + RC C Y
Sbjct: 1444 AGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYE 1502
Query: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDP-NLIFEDCDEVTGQCRNCLRNTTGFKC 221
G CERCAPGY G+P G +C++C+C DP + CD VTG C C TG KC
Sbjct: 1503 GQYCERCAPGYTGSPGNPGGSCQECEC----DPYGSLPVPCDPVTGFC-TCRPGATGRKC 1557
Query: 222 ERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAA 281
+ C + AR C C G C + L D RL
Sbjct: 1558 DGCK---HWHAREGWECVFC---GDECTGLL--------------------LGDLARLEQ 1591
Query: 282 LSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKS 341
+ + +G L A ++ + + LK LS + L I AE + +
Sbjct: 1592 MVMSINLTGPL-----PAPYKMLYGLENMTQELKHLLSPQRAPERL----IQLAEGNLNT 1642
Query: 342 LLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEE 401
L++++ EL+ + + + G+ +++ T A L E ++ + +N K + E
Sbjct: 1643 LVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNET 1702
Query: 402 HELSPKEISEKLVLAQK----MLEEIRSRQPFFTQRELVDEEADEAYELLSQAES-WQRL 456
+ L QK M++E+R R+ TQ+E+ ++E A LL + + +
Sbjct: 1703 LGTRDEAFERNLEGLQKEIDQMIKELR-RKNLETQKEIAEDELVAAEALLKKVKKLFGES 1761
Query: 457 HNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDH---EKQQ 513
E + + E+L DY K+ D + L +A + +R+A NR A Q++ EK++
Sbjct: 1762 RGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREA---NRLFAVNQKNMTALEKKK 1818
Query: 514 ERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLS 573
E V + +L D L E++ II I ++ EL K+ +LS
Sbjct: 1819 EAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLS 1878
Query: 574 NLSHD-LVQEAIDHAQDLQQEANELSRKLHS--SDMNGLVQKALDASNVYENIVNYVSEA 630
D + E + A+ + N+ S L + + A A Y NI +Y+ EA
Sbjct: 1879 QEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFKAYSNIKDYIDEA 1938
Query: 631 NETAEFALNTTDRIYDAVSG----IDTQIIYHKDESENLLNQARELQAKAESSSDEAVAD 686
+ A+ A + +G + +S +LN+A++L + + D +
Sbjct: 1939 EKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVKENEDH-LNG 1997
Query: 687 TSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATA 746
R+ A AR L L+D + +L A D +L + +AN T +V
Sbjct: 1998 LKTRIENADARNGDLLRTLNDTLGKLSAIP-NDTAAKLQAVKDKARQANDTAKDVLAQIT 2056
Query: 747 PMANNLTNWSQNLQHFDSS-----------AYNTAVNSARDAVRNLTEVVPQLLDQLRTV 795
+ NL +N S + N + A V+NL + +L+D+L+ +
Sbjct: 2057 ELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPI 2116
Query: 796 EQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLK--AFTS 853
K N+ +I I+ELI Q R A+ I+VS+ G RT ++K ++ +
Sbjct: 2117 --KELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCI-----RTYKPEIKKGSYNN 2169
Query: 854 LSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLD 913
+ + +K T AD + YLGS +++ + ++ + +++++G+ +
Sbjct: 2170 IVVNVK--------TAVADNLLFYLGSAKF-IDFLAIEMRKGKVSFLWDVGSGVGRVEYP 2220
Query: 914 SKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDT 973
+ +Y+ + R G++G + + + ++LD+D +
Sbjct: 2221 DLTIDD--SYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVD-ANA 2277
Query: 974 VFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIY-NMDPSTSVPCARDK 1032
+ +VGG+ K ++ + F GC+ +N I L+NF+ + T P D
Sbjct: 2278 MLFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDS 2337
Query: 1033 LAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSM--F 1090
Q FDG GYA+V R + ++ + RT + + L++ + + F
Sbjct: 2338 EGTIQ-------FDGEGYALVSRPIR--WYPNISTVMFKFRTFSSSALLMYLATRDLRDF 2388
Query: 1091 FRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVD--- 1147
+E+ +G++ V YD G SG + + ND K+ ++ + I +VD
Sbjct: 2389 MSVELTDGHIKVSYDLG-SG----MASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDT 2443
Query: 1148 --RRHV---KSMDNEKMKIPFTD-IYIGGAPPEILQSRALRAHLPLDI-NFRGCMKGFQF 1200
++ S +N + + D IY GG P L++ +++A +++ + GC+K +
Sbjct: 2444 NQEENIATSSSGNNFGLDLKADDKIYFGGLP--TLRNLSMKARPEVNLKKYSGCLKDIEI 2501
Query: 1201 QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQ 1260
+ +N+L + +GV GC +++ + F F+ + + G E +F T
Sbjct: 2502 SRTPYNILSSPDYVGVTKGCSLENVYT--VSFPKPGFV-ELSPVPIDVGTEINLSFSTKN 2558
Query: 1261 PNGLLFYYASGSDV-------------FSISLDNG-------TVIMDVKGIKVQSVDKQY 1300
+G++ + G+ + I L+ G T ++ I ++ +
Sbjct: 2559 ESGIILLGSGGTPAPPRRKRRQTGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLF 2618
Query: 1301 NDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQ---- 1356
+DG H V + + + VD++R +N T +EQ KK + GG+P Q
Sbjct: 2619 HDGREHSVHVERTRGIFTVQVDENRRYMQNLT---VEQ-PIEVKKLFVGGAPPEFQPSPL 2674
Query: 1357 --YANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSK 1414
F GCI N V DF R + + C +
Sbjct: 2675 RNIPPFEGCIWNLVINSVPM-----DFARPVSFKNADIGRC-----------------AH 2712
Query: 1415 PKASQNKKGGKSKD-APSWDPVALKLPERNTPRNSH--CHLSNSPRAIEHAYQYGGTANS 1471
K +++ G + +PV TP +H C + P + + Q+G + NS
Sbjct: 2713 QKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALLIGSKQFGLSRNS 2772
Query: 1472 RQEFEHLKGDFGAKSQFSIRL--RTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVG 1529
D K++ +I L RT + G++FY++ DF T+ L +G + +++G
Sbjct: 2773 HIAIAF--DDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLG 2830
Query: 1530 HKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEA-TWKIKGPIYLG 1588
K NDG WH + +R + G L +DG ++ P +A + G +Y+G
Sbjct: 2831 SGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDG--ASNRTISPKKADILDVVGMLYVG 2888
Query: 1589 GVAPGKAVKNVQINSIYSFSGCLSNLQL--NGASITSASQTFSVTPCFEGPMETGTYFST 1646
G+ + + YS GC+ NL + A + + +F V CF + GTYF
Sbjct: 2889 GLPINYTTRRIG-PVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFAN-AQRGTYFDG 2946
Query: 1647 EGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGI 1706
G+ F +GL + FE R +++G L+ S + + + M + +++ V+NG
Sbjct: 2947 T-GFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFHVDNGA 3005
Query: 1707 RDFST--SVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNP--KPIDHREPV 1762
F+ LCDG+WH++T + + ++L VD P NP D +PV
Sbjct: 3006 GRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSP-NPASTSADTNDPV 3064
Query: 1763 FVGGVPESLLTPRLAPSKPFTGCIRHFVI---DGHP--VSFSKAALVSGAVSINSCPA 1815
FVGG P+ L L S PF GCIR + G P V+F+KA + G + SCPA
Sbjct: 3065 FVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPV-SCPA 3121
Score = 175 bits (444), Expect = 3e-43
Identities = 88/216 (40%), Positives = 117/216 (54%), Gaps = 12/216 (5%)
Query: 62 PAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
P + N F G C PC C G++ C D +G C++C+ +T G +C+KCL G+ G+
Sbjct: 740 PRHRRVNGTIF---GGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEP 796
Query: 122 IRGAPQFCQPCPCPLPHLA-NFAESCY--RKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
+G + CQPC CPL + NF+ +C+ R G + C Y GP CERCA GY+G P
Sbjct: 797 TKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS 856
Query: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC 238
+ G +C+ C C+ N D + I CD ++G C C TTG CE CA GY+GDA AKNC
Sbjct: 857 VPGGSCQPCQCNDNLDFS-IPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNC 915
Query: 239 AVCNCGGG-----PCDSVTGECLEEGFEPPTGCDKC 269
C C G C S TG+C CDKC
Sbjct: 916 QPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKC 951
Score = 132 bits (332), Expect = 3e-30
Identities = 79/223 (35%), Positives = 106/223 (47%), Gaps = 25/223 (11%)
Query: 57 LGRLPPAAEKCNAGFFHTLS---GECVPCDCNGNSNECLDGS-----GYCVHCQRNTTGE 108
+G P E+C G+F S G C PC CN N + + GS G C+ C+ TTG
Sbjct: 837 VGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGR 896
Query: 109 HCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCER 168
+CE C DGY GD++ + CQPC C +F+E C+ + G +C C N G C++
Sbjct: 897 YCELCADGYFGDAVDA--KNCQPCRCNAG--GSFSEVCHSQTG--QCECRANVQGQRCDK 950
Query: 169 CAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGY 228
C G +G L C C+C+ + DC+E +GQC C TG KC+RCA GY
Sbjct: 951 CKAGTFG--LQSARGCVPCNCNSFGSKSF---DCEE-SGQCW-CQPGVTGKKCDRCAHGY 1003
Query: 229 YGDARIAKNCAVCNCG--GGPCDSVTGECLEEGFEPPTGCDKC 269
+ C C C G CD TG C+ C KC
Sbjct: 1004 FNFQE--GGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKC 1044
Score = 110 bits (275), Expect = 1e-23
Identities = 74/199 (37%), Positives = 98/199 (49%), Gaps = 30/199 (15%)
Query: 65 EKCNAGFFHTLSGE-CVPCDCNGNSNECLD--GSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
+KC AG F S CVPC+CN ++ D SG C CQ TG+ C++C GY
Sbjct: 949 DKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQC-WCQPGVTGKKCDRCAHGYFNFQ 1007
Query: 122 IRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIG 181
G C C C HL N +C K G RCIC N G C +CAP +G+ + G
Sbjct: 1008 EGG----CTACECS--HLGN---NCDPKTG--RCICPPNTIGEKCSKCAPNTWGHSITTG 1056
Query: 182 STCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVC 241
CK C+CS + +L F+ C+ TGQC NC +G KC C+ G++ R C +C
Sbjct: 1057 --CKACNCS--TVGSLDFQ-CNVNTGQC-NCHPKFSGAKCTECSRGHWNYPR----CNLC 1106
Query: 242 NC-----GGGPCDSVTGEC 255
+C CDS T +C
Sbjct: 1107 DCFLPGTDATTCDSETKKC 1125
Score = 102 bits (254), Expect = 3e-21
Identities = 63/200 (31%), Positives = 87/200 (43%), Gaps = 26/200 (13%)
Query: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
++C G+F+ G C C+C+ N C +G C+ C NT GE C KC G SI
Sbjct: 997 DRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCI-CPPNTIGEKCSKCAPNTWGHSITT 1055
Query: 125 APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
C+ C C +F C G +C C+ ++G C C+ G++ P C
Sbjct: 1056 G---CKACNCSTVGSLDF--QCNVNTG--QCNCHPKFSGAKCTECSRGHWNYP-----RC 1103
Query: 185 KKCDC------SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKN 237
CDC + D C + TGQC C N G C+RC PG +G DA+
Sbjct: 1104 NLCDCFLPGTDATTCDSETKKCSCSDQTGQC-TCKVNVEGIHCDRCRPGKFGLDAKNPLG 1162
Query: 238 CAVCNCGGGPCDSVTGECLE 257
C+ C C G T +C E
Sbjct: 1163 CSSCYCFG-----TTTQCSE 1177
Score = 99.8 bits (247), Expect = 2e-20
Identities = 76/261 (29%), Positives = 105/261 (40%), Gaps = 48/261 (18%)
Query: 69 AGFFHTLSGECVPCDCNGNSNECLD------------------GSGYCVHCQRNTTGEHC 110
AG F T + EC C+C+G + EC G G C++C +NT G +C
Sbjct: 332 AGTFLTKT-ECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINC 390
Query: 111 EKCLDGYIGDSIRGAPQFCQPC-PCPLPHLANFAESCYRKNGAVR-------CICNENYA 162
E C DG+ +P + +PC PC + + E C + R C C +
Sbjct: 391 ETCTDGFFRPK-GVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFG 449
Query: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCE 222
G +C+RCA GY G P CK C+CSG N D G C C N G C
Sbjct: 450 GVSCDRCARGYTGYP-----DCKACNCSGLGSKNE-----DPCFGPC-ICKENVEGGDCS 498
Query: 223 RCAPGYYG-DARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTD---ALR 278
RC G++ K C C C G V+ C + D W LTD +R
Sbjct: 499 RCKSGFFNLQEDNWKGCDECFCSG-----VSNRCQSSYWTYGKIQDMSGWYLTDLPGRIR 553
Query: 279 LAALSIEEGKSGVLSVSSGAA 299
+A + +S+S+ A
Sbjct: 554 VAPQQDDLDSPQQISISNAEA 574
Score = 77.0 bits (188), Expect = 2e-13
Identities = 53/175 (30%), Positives = 72/175 (41%), Gaps = 42/175 (24%)
Query: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRK----NGAV----------------------R 154
SI A + CQ CP + + ESC+ + NG +
Sbjct: 716 SIAAAVEVCQ---CPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGE 772
Query: 155 CI-CNENYAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDC--DEVTGQ-C 209
C+ C ++ GP C++C PG+YG P C+ C C N N C D G C
Sbjct: 773 CLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLIC 832
Query: 210 RNCLRNTTGFKCERCAPGYYGDARI-AKNCAVCNCGG-------GPCDSVTGECL 256
C TG +CERCA GY+G + +C C C G CDS++G CL
Sbjct: 833 DGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCL 887
Score = 70.9 bits (172), Expect = 1e-11
Identities = 67/239 (28%), Positives = 91/239 (38%), Gaps = 58/239 (24%)
Query: 82 CDCNGNSNEC-LD---GSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
C C G++ C LD C C+ NT G+ C++C G+ R A F C
Sbjct: 287 CICYGHARACPLDPATNKSRC-ECEHNTCGDSCDQCCPGFHQKPWR-AGTFLTKTECEAC 344
Query: 138 HLANFAESCY------RKN-----------GAVRCICNENYAGPNCERCAPGYY---GNP 177
+ AE CY R+N G V C +N AG NCE C G++ G
Sbjct: 345 NCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVS 404
Query: 178 LLIGSTCKKCDCSGNSDPNLIFEDCDE------VTGQCRNCLRNTTGFKCERCAPGYYGD 231
C+ C C N + ++ G C +C G C+RCA GY G
Sbjct: 405 PNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSC-HCKTGFGGVSCDRCARGYTG- 462
Query: 232 ARIAKNCAVCNCGG----------GPC----DSVTGEC--LEEGF-----EPPTGCDKC 269
+C CNC G GPC + G+C + GF + GCD+C
Sbjct: 463 ---YPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDEC 518
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 419 bits (1078), Expect = e-116
Identities = 452/1857 (24%), Positives = 773/1857 (41%), Gaps = 221/1857 (11%)
Query: 57 LGRLPPAAEKCNAGFFHTLS-----------GECVPCDCNGNSNECLDGSGYCVHCQRNT 105
LG + E C GF+ S G CVPC CNG+S+ C + C +CQ +T
Sbjct: 1384 LGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHT 1443
Query: 106 TGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLA-NFAESCYRKN-GAVRC-ICNENYA 162
G+ CE+C GY G ++G P CQ C CPL + NF+ SC + RC C Y
Sbjct: 1444 AGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYE 1502
Query: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDP-NLIFEDCDEVTGQCRNCLRNTTGFKC 221
G CERCAPGY G+P G +C++C+C DP + CD VTG C C TG KC
Sbjct: 1503 GQYCERCAPGYTGSPGNPGGSCQECEC----DPYGSLPVPCDPVTGFC-TCRPGATGRKC 1557
Query: 222 ERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAA 281
+ C + AR C C G C + L D RL
Sbjct: 1558 DGCK---HWHAREGWECVFC---GDECTGLL--------------------LGDLARLEQ 1591
Query: 282 LSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKS 341
+ + +G L A ++ + + LK LS + L I AE + +
Sbjct: 1592 MVMSINLTGPL-----PAPYKMLYGLENMTQELKHLLSPQRAPERL----IQLAEGNLNT 1642
Query: 342 LLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEE 401
L++++ EL+ + + + G+ +++ T A L E ++ + +N K + E
Sbjct: 1643 LVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNET 1702
Query: 402 HELSPKEISEKLVLAQK----MLEEIRSRQPFFTQRELVDEEADEAYELLSQAES-WQRL 456
+ L QK M++E+R R+ TQ+E+ ++E A LL + + +
Sbjct: 1703 LGTRDEAFERNLEGLQKEIDQMIKELR-RKNLETQKEIAEDELVAAEALLKKVKKLFGES 1761
Query: 457 HNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDH---EKQQ 513
E + + E+L DY K+ D + L +A + +R+A NR A Q++ EK++
Sbjct: 1762 RGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREA---NRLFAVNQKNMTALEKKK 1818
Query: 514 ERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLS 573
E V + +L D L E++ II I ++ EL K+ +LS
Sbjct: 1819 EAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLS 1878
Query: 574 NLSHD-LVQEAIDHAQDLQQEANELSRKLHS--SDMNGLVQKALDASNVYENIVNYVSEA 630
D + E + A+ + N+ S L + + A A Y NI +Y+ EA
Sbjct: 1879 QEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFKAYSNIKDYIDEA 1938
Query: 631 NETAEFALNTTDRIYDAVSG----IDTQIIYHKDESENLLNQARELQAKAESSSDEAVAD 686
+ A+ A + +G + +S +LN+A++L + + D +
Sbjct: 1939 EKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVKENEDH-LNG 1997
Query: 687 TSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATA 746
R+ A AR L L+D + +L A D +L + +AN T +V
Sbjct: 1998 LKTRIENADARNGDLLRTLNDTLGKLSAIP-NDTAAKLQAVKDKARQANDTAKDVLAQIT 2056
Query: 747 PMANNLTNWSQNLQHFDSS-----------AYNTAVNSARDAVRNLTEVVPQLLDQLRTV 795
+ NL +N S + N + A V+NL + +L+D+L+ +
Sbjct: 2057 ELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPI 2116
Query: 796 EQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLK--AFTS 853
K N+ +I I+ELI Q R A+ I+VS+ G RT ++K ++ +
Sbjct: 2117 --KELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCI-----RTYKPEIKKGSYNN 2169
Query: 854 LSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLD 913
+ + +K T AD + YLGS +++ + ++ + +++++G+ +
Sbjct: 2170 IVVNVK--------TAVADNLLFYLGSAKF-IDFLAIEMRKGKVSFLWDVGSGVGRVEYP 2220
Query: 914 SKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDT 973
+ +Y+ + R G++G + + + ++LD+D +
Sbjct: 2221 DLTIDD--SYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVD-ANA 2277
Query: 974 VFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIY-NMDPSTSVPCARDK 1032
+ +VGG+ K ++ + F GC+ +N I L+NF+ + T P D
Sbjct: 2278 MLFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDS 2337
Query: 1033 LAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSM--F 1090
Q FDG GYA+V R + ++ + RT + + L++ + + F
Sbjct: 2338 EGTIQ-------FDGEGYALVSRPIR--WYPNISTVMFKFRTFSSSALLMYLATRDLRDF 2388
Query: 1091 FRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVD--- 1147
+E+ +G++ V YD G SG + + ND K+ ++ + I +VD
Sbjct: 2389 MSVELTDGHIKVSYDLG-SG----MASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDT 2443
Query: 1148 --RRHV---KSMDNEKMKIPFTD-IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQ 1201
++ S +N + + D IY GG P R LR + L + GC+K +
Sbjct: 2444 NQEENIATSSSGNNFGLDLKADDKIYFGGLP----TLRNLRPEVNLK-KYSGCLKDIEIS 2498
Query: 1202 KKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQP 1261
+ +N+L + +GV GC +++ + F F+ + + G E +F T
Sbjct: 2499 RTPYNILSSPDYVGVTKGCSLENVYT--VSFPKPGFV-ELSPVPIDVGTEINLSFSTKNE 2555
Query: 1262 NGLLFYYASGSDV-------------FSISLDNG-------TVIMDVKGIKVQSVDKQYN 1301
+G++ + G+ + I L+ G T ++ I ++ ++
Sbjct: 2556 SGIILLGSGGTPAPPRRKRRQTGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFH 2615
Query: 1302 DGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQ----- 1356
DG H V + + + VD++R +N T +EQ KK + GG+P Q
Sbjct: 2616 DGREHSVHVERTRGIFTVQVDENRRYMQNLT---VEQ-PIEVKKLFVGGAPPEFQPSPLR 2671
Query: 1357 -YANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKP 1415
F GCI N V DF R + + C +
Sbjct: 2672 NIPPFEGCIWNLVINSVPM-----DFARPVSFKNADIGRC-----------------AHQ 2709
Query: 1416 KASQNKKGGKSKD-APSWDPVALKLPERNTPRNSH--CHLSNSPRAIEHAYQYGGTANSR 1472
K +++ G + +PV TP +H C + P + + Q+G + NS
Sbjct: 2710 KLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALLIGSKQFGLSRNSH 2769
Query: 1473 QEFEHLKGDFGAKSQFSIRL--RTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGH 1530
D K++ +I L RT + G++FY++ DF T+ L +G + +++G
Sbjct: 2770 IAIAF--DDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLGS 2827
Query: 1531 KKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEA-TWKIKGPIYLGG 1589
K NDG WH + +R + G L +DG ++ P +A + G +Y+GG
Sbjct: 2828 GDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDG--ASNRTISPKKADILDVVGMLYVGG 2885
Query: 1590 VAPGKAVKNVQINSIYSFSGCLSNLQL--NGASITSASQTFSVTPCFEGPMETGTYFSTE 1647
+ + + YS GC+ NL + A + + +F V CF + GTYF
Sbjct: 2886 LPINYTTRRIG-PVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFAN-AQRGTYFDGT 2943
Query: 1648 GGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIR 1707
G+ F +GL + FE R +++G L+ S + + + M + +++ V+NG
Sbjct: 2944 -GFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFHVDNGAG 3002
Query: 1708 DFST--SVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNP--KPIDHREPVF 1763
F+ LCDG+WH++T + + ++L VD P NP D +PVF
Sbjct: 3003 RFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSP-NPASTSADTNDPVF 3061
Query: 1764 VGGVPESLLTPRLAPSKPFTGCIRHFVI---DGHP--VSFSKAALVSGAVSINSCPA 1815
VGG P+ L L S PF GCIR + G P V+F+KA + G + SCPA
Sbjct: 3062 VGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPV-SCPA 3117
Score = 175 bits (444), Expect = 3e-43
Identities = 88/216 (40%), Positives = 117/216 (54%), Gaps = 12/216 (5%)
Query: 62 PAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
P + N F G C PC C G++ C D +G C++C+ +T G +C+KCL G+ G+
Sbjct: 740 PRHRRVNGTIF---GGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEP 796
Query: 122 IRGAPQFCQPCPCPLPHLA-NFAESCY--RKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
+G + CQPC CPL + NF+ +C+ R G + C Y GP CERCA GY+G P
Sbjct: 797 TKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPS 856
Query: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC 238
+ G +C+ C C+ N D + I CD ++G C C TTG CE CA GY+GDA AKNC
Sbjct: 857 VPGGSCQPCQCNDNLDFS-IPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNC 915
Query: 239 AVCNCGGG-----PCDSVTGECLEEGFEPPTGCDKC 269
C C G C S TG+C CDKC
Sbjct: 916 QPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKC 951
Score = 132 bits (332), Expect = 3e-30
Identities = 79/223 (35%), Positives = 106/223 (47%), Gaps = 25/223 (11%)
Query: 57 LGRLPPAAEKCNAGFFHTLS---GECVPCDCNGNSNECLDGS-----GYCVHCQRNTTGE 108
+G P E+C G+F S G C PC CN N + + GS G C+ C+ TTG
Sbjct: 837 VGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGR 896
Query: 109 HCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCER 168
+CE C DGY GD++ + CQPC C +F+E C+ + G +C C N G C++
Sbjct: 897 YCELCADGYFGDAVDA--KNCQPCRCNAG--GSFSEVCHSQTG--QCECRANVQGQRCDK 950
Query: 169 CAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGY 228
C G +G L C C+C+ + DC+E +GQC C TG KC+RCA GY
Sbjct: 951 CKAGTFG--LQSARGCVPCNCNSFGSKSF---DCEE-SGQCW-CQPGVTGKKCDRCAHGY 1003
Query: 229 YGDARIAKNCAVCNCG--GGPCDSVTGECLEEGFEPPTGCDKC 269
+ C C C G CD TG C+ C KC
Sbjct: 1004 FNFQE--GGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKC 1044
Score = 110 bits (275), Expect = 1e-23
Identities = 74/199 (37%), Positives = 98/199 (49%), Gaps = 30/199 (15%)
Query: 65 EKCNAGFFHTLSGE-CVPCDCNGNSNECLD--GSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
+KC AG F S CVPC+CN ++ D SG C CQ TG+ C++C GY
Sbjct: 949 DKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQC-WCQPGVTGKKCDRCAHGYFNFQ 1007
Query: 122 IRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIG 181
G C C C HL N +C K G RCIC N G C +CAP +G+ + G
Sbjct: 1008 EGG----CTACECS--HLGN---NCDPKTG--RCICPPNTIGEKCSKCAPNTWGHSITTG 1056
Query: 182 STCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVC 241
CK C+CS + +L F+ C+ TGQC NC +G KC C+ G++ R C +C
Sbjct: 1057 --CKACNCS--TVGSLDFQ-CNVNTGQC-NCHPKFSGAKCTECSRGHWNYPR----CNLC 1106
Query: 242 NC-----GGGPCDSVTGEC 255
+C CDS T +C
Sbjct: 1107 DCFLPGTDATTCDSETKKC 1125
Score = 102 bits (254), Expect = 3e-21
Identities = 63/200 (31%), Positives = 87/200 (43%), Gaps = 26/200 (13%)
Query: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
++C G+F+ G C C+C+ N C +G C+ C NT GE C KC G SI
Sbjct: 997 DRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCI-CPPNTIGEKCSKCAPNTWGHSITT 1055
Query: 125 APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
C+ C C +F C G +C C+ ++G C C+ G++ P C
Sbjct: 1056 G---CKACNCSTVGSLDF--QCNVNTG--QCNCHPKFSGAKCTECSRGHWNYP-----RC 1103
Query: 185 KKCDC------SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKN 237
CDC + D C + TGQC C N G C+RC PG +G DA+
Sbjct: 1104 NLCDCFLPGTDATTCDSETKKCSCSDQTGQC-TCKVNVEGIHCDRCRPGKFGLDAKNPLG 1162
Query: 238 CAVCNCGGGPCDSVTGECLE 257
C+ C C G T +C E
Sbjct: 1163 CSSCYCFG-----TTTQCSE 1177
Score = 99.8 bits (247), Expect = 2e-20
Identities = 76/261 (29%), Positives = 105/261 (40%), Gaps = 48/261 (18%)
Query: 69 AGFFHTLSGECVPCDCNGNSNECLD------------------GSGYCVHCQRNTTGEHC 110
AG F T + EC C+C+G + EC G G C++C +NT G +C
Sbjct: 332 AGTFLTKT-ECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINC 390
Query: 111 EKCLDGYIGDSIRGAPQFCQPC-PCPLPHLANFAESCYRKNGAVR-------CICNENYA 162
E C DG+ +P + +PC PC + + E C + R C C +
Sbjct: 391 ETCTDGFFRPK-GVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFG 449
Query: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCE 222
G +C+RCA GY G P CK C+CSG N D G C C N G C
Sbjct: 450 GVSCDRCARGYTGYP-----DCKACNCSGLGSKNE-----DPCFGPC-ICKENVEGGDCS 498
Query: 223 RCAPGYYG-DARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTD---ALR 278
RC G++ K C C C G V+ C + D W LTD +R
Sbjct: 499 RCKSGFFNLQEDNWKGCDECFCSG-----VSNRCQSSYWTYGKIQDMSGWYLTDLPGRIR 553
Query: 279 LAALSIEEGKSGVLSVSSGAA 299
+A + +S+S+ A
Sbjct: 554 VAPQQDDLDSPQQISISNAEA 574
Score = 77.0 bits (188), Expect = 2e-13
Identities = 53/175 (30%), Positives = 72/175 (41%), Gaps = 42/175 (24%)
Query: 121 SIRGAPQFCQPCPCPLPHLANFAESCYRK----NGAV----------------------R 154
SI A + CQ CP + + ESC+ + NG +
Sbjct: 716 SIAAAVEVCQ---CPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGE 772
Query: 155 CI-CNENYAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDC--DEVTGQ-C 209
C+ C ++ GP C++C PG+YG P C+ C C N N C D G C
Sbjct: 773 CLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLIC 832
Query: 210 RNCLRNTTGFKCERCAPGYYGDARI-AKNCAVCNCGG-------GPCDSVTGECL 256
C TG +CERCA GY+G + +C C C G CDS++G CL
Sbjct: 833 DGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCL 887
Score = 70.9 bits (172), Expect = 1e-11
Identities = 67/239 (28%), Positives = 91/239 (38%), Gaps = 58/239 (24%)
Query: 82 CDCNGNSNEC-LD---GSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
C C G++ C LD C C+ NT G+ C++C G+ R A F C
Sbjct: 287 CICYGHARACPLDPATNKSRC-ECEHNTCGDSCDQCCPGFHQKPWR-AGTFLTKTECEAC 344
Query: 138 HLANFAESCY------RKN-----------GAVRCICNENYAGPNCERCAPGYY---GNP 177
+ AE CY R+N G V C +N AG NCE C G++ G
Sbjct: 345 NCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVS 404
Query: 178 LLIGSTCKKCDCSGNSDPNLIFEDCDE------VTGQCRNCLRNTTGFKCERCAPGYYGD 231
C+ C C N + ++ G C +C G C+RCA GY G
Sbjct: 405 PNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSC-HCKTGFGGVSCDRCARGYTG- 462
Query: 232 ARIAKNCAVCNCGG----------GPC----DSVTGEC--LEEGF-----EPPTGCDKC 269
+C CNC G GPC + G+C + GF + GCD+C
Sbjct: 463 ---YPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDEC 518
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 394 bits (1011), Expect = e-109
Identities = 426/1830 (23%), Positives = 765/1830 (41%), Gaps = 214/1830 (11%)
Query: 58 GRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117
G+LP +++ L CVPC CN +S+ C +G C++C NT G+HC+ C GY
Sbjct: 1383 GKLPAGSDRGP----RPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGY 1438
Query: 118 IGDSIRGAPQFCQPCPCPLPHLANFAESCYRK-NGAVRC-ICNENYAGPNCERCAPGYYG 175
G + G+ C C CP A+F+ +C + + RC C Y G +CERC+ YYG
Sbjct: 1439 YG-KVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYG 1497
Query: 176 NPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
NP G +C+KCDC+ + + DCD +GQC C +G +C+ C P + +
Sbjct: 1498 NPQTPGGSCQKCDCNPHGS---VHGDCDRTSGQC-VCRLGASGLRCDECEPRH---ILME 1550
Query: 236 KNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVS 295
+C C+ D G L + D + A LS+ +G++ V
Sbjct: 1551 TDCVSCD------DECVGVLLND---------------LDEIGDAVLSL--NLTGIIPVP 1587
Query: 296 SGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQ 355
G + N N T YL ++ L E Q L KI++ +L + ++ +
Sbjct: 1588 YGILS----NLENTTKYLQESLLKE-NMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQK 1642
Query: 356 ASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVL 415
+R + + KES D +L ++ +K +N + +E L P + +
Sbjct: 1643 VNRATERIFKESQDLAIAIERLQMSITEIMEK-TTLNQTL----DEDFLLPNSTLQNMQQ 1697
Query: 416 AQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQ-AESWQRLHNETRTLFPVVLEQLDDY 474
L EI + F + E A +LLSQ E++Q+ E L L +
Sbjct: 1698 NGTSLLEIMQIRDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKH 1757
Query: 475 NAKLSDLQ------EALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLS 528
N +L + EA Q N++ + N + ++ H ++++ + ++ V L
Sbjct: 1758 NNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLI 1817
Query: 529 TSADSLT-TPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHA 587
+A + T + L L+D A+I +L + +S + + DLV A DHA
Sbjct: 1818 DAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQRNAV--DLVYRAEDHA 1875
Query: 588 QDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDA 647
+ Q+ A+ L L ++ + A A+ V+ NI + + E+ E A A T
Sbjct: 1876 AEFQRLADVLYSGL--ENIRNVSLNATSAAYVHYNIQSLIEESEELARDAHRTVTETSLL 1933
Query: 648 VSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSD 707
+ + S L + L K + E +++ + + + ++
Sbjct: 1934 SESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALE-LSELRNKTNRFQENAVEITRQTNE 1992
Query: 708 AVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAY 767
++ L+A +G + + +++ + A+++ + + A ++ L N S +L +++
Sbjct: 1993 SLLILRAIPKG-IRDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLR 2051
Query: 768 NT---------AVNSARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQT 818
T A A V+++ L D+L+ + K N+S ++ I+ LI+Q
Sbjct: 2052 ETHQLLQDSTMATLLAGRKVKDVEIQANLLFDRLKPL--KMLEENLSRNLSEIKLLISQA 2109
Query: 819 RSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYL 878
R A+ I+V++ D + S + + +L+L +K T+ D + YL
Sbjct: 2110 RKQAASIKVAVSADRDCIRAYQPQISSTN---YNTLTLNVK--------TQEPDNLLFYL 2158
Query: 879 GSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPV--SSWPAYFSIVKIERVGKHG 936
GS A +++ + ++ + ++++LG+ + P+ + W + + + R G G
Sbjct: 2159 GSSTA-SDFLAVEMRRGRVAFLWDLGSGSTRLEFPDFPIDDNRWHS----IHVARFGNIG 2213
Query: 937 KVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFV 996
L+V +SS ++ K + G ++LD++ T+ +VGG+ K ++ + F
Sbjct: 2214 S--LSVKEMSSN-QKSPTKTSKSPGTANVLDVN-NSTLMFVGGLGGQIKKSPAVKVTHFK 2269
Query: 997 GCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDI 1056
GCL A LN I L+N+ R +Q+ S+ FDGSGY+VV
Sbjct: 2270 GCLGEAFLNGKSIGLWNYIEREGK--------CRGCFGSSQNEDPSFHFDGSGYSVV--- 2318
Query: 1057 TRRGKFGQVTRFDIEVRTPADNGLILLM--VNGSMFFRLEMRNGYLHVFYDFGFSGGPVH 1114
+ VT+ + T + NGL+L + F +E+ G + V D G GP+
Sbjct: 2319 -EKSLPATVTQIIMLFNTFSPNGLLLYLGSYGTKDFLSIELFRGRVKVMTDLG--SGPIT 2375
Query: 1115 LEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKIPFTD--------- 1165
L L + N+ +++I+ + + ++ V+D + + + ++ + P
Sbjct: 2376 L---LTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKETKQGETPGASSDLNRLDKD 2432
Query: 1166 -IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYGCPEDS 1224
IY+GG P +SR +R + +F GC+K + + F+LL + GV GC +
Sbjct: 2433 PIYVGGLP----RSRVVRRGVTTK-SFVGCIKNLEISRSTFDLLR--NSYGVRKGCLLEP 2485
Query: 1225 LISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDV---------- 1274
+ R F +I K S E F T +G++ A G DV
Sbjct: 2486 I--RSVSFLKGGYIELPPK-SLSPESEWLVTFATTNSSGIIL-AALGGDVEKRGDREEAH 2541
Query: 1275 ---FSISLDNGTVIMDVK-----GIK---VQSVDKQYNDGLSHFVISSVSPTRYELIVDK 1323
FS+ L G + + V G++ + + +DG +H S+S R I+
Sbjct: 2542 VPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAH----SISLVRNRRII-T 2596
Query: 1324 SRVGSKNPTKGK----IEQTQASEKKFYFGGSP------ISAQYANFTGCISNAYFTRVD 1373
++ NP + K +E + Y GG P + +F GCI N F
Sbjct: 2597 VQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMRRSFHGCIKNLIF---- 2652
Query: 1374 RDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWD 1433
++E+ DF L C + +PK + + + K P
Sbjct: 2653 -NLELLDFNSAVGHEQVDLDTCWLS--------------ERPKLAPDAEDSKLLPEPRAF 2697
Query: 1434 PVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLR 1493
P C + + + A+Q+G T NS + K + +R
Sbjct: 2698 P-------------EQCVVDAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKLSVELSIR 2744
Query: 1494 TRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIR 1553
T +S G+I+Y++ Q + D+ L L GRL +MF++G + K+ +DG WH V
Sbjct: 2745 TFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDY 2804
Query: 1554 ERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSN 1613
+ G + +DG ++ ++G YLGG+ + + N +S C+ +
Sbjct: 2805 VKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIG-NITHSIPACIGD 2863
Query: 1614 LQLNGASITSAS--QTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRP 1671
+ +N + S F+V C+ E GTYF G ++ E + + I E R
Sbjct: 2864 VTVNSKQLDKDSPVSAFTVNRCYAVAQE-GTYFDGSGYAALVKEGYKVQSDVNITLEFRT 2922
Query: 1672 RSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQS--LCDGRWHRITV 1729
S +G L+ + + + + + +G+V+ VNNG + + PK + LCDG+WH +
Sbjct: 2923 SSQNGVLLGISTAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQA 2982
Query: 1730 IRDSNVVQLDVDSEVNHVVGP-LNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRH 1788
+ + + L VD P +D P++VGG P + L F GC+R
Sbjct: 2983 NKSKHRITLIVDGNAVGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRK 3042
Query: 1789 FVIDGHP----VSFSKAALVSGAVSINSCP 1814
+ P FS+A + G V ++SCP
Sbjct: 3043 LALIKSPQVQSFDFSRAFELHG-VFLHSCP 3071
Score = 199 bits (505), Expect = 3e-50
Identities = 103/248 (41%), Positives = 133/248 (53%), Gaps = 14/248 (5%)
Query: 35 DIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHT----LSGECVPCDCNGNSNE 90
DI S+A+ + G + E C +G++ G C PC+C+G++ E
Sbjct: 691 DIASSNAIDLVVAADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAE 750
Query: 91 CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLAN-FAESCYRK 149
C + G C+ C NTTG HCE+CL G+ G+ RG P CQPC CPL +N F+ +C+
Sbjct: 751 C-NVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLN 809
Query: 150 NG--AVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTG 207
+G V C Y+G CERCA GYYGNP + G +C CDCSGN DP+ CD VTG
Sbjct: 810 DGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGH-CDSVTG 868
Query: 208 QCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC-----GGGPCDSVTGECLEEGFEP 262
+C CL NT G CERCA G+YGDA AKNC C C C TG C +
Sbjct: 869 ECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVT 928
Query: 263 PTGCDKCV 270
CD+C+
Sbjct: 929 GQQCDQCL 936
Score = 127 bits (318), Expect = 1e-28
Identities = 74/215 (34%), Positives = 110/215 (51%), Gaps = 25/215 (11%)
Query: 65 EKCNAGFFH--TLSGE-CVPCDCNGN-----SNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
E+C G++ T+ GE CVPCDC+GN + C +G C+ C NT G HCE+C DG
Sbjct: 829 ERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADG 888
Query: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176
+ GD++ + C+ C C + + + C+ + G C C N G C++C GYYG
Sbjct: 889 FYGDAVTA--KNCRACECHVK--GSHSAVCHLETGL--CDCKPNVTGQQCDQCLHGYYG- 941
Query: 177 PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK 236
L G C+ C+CS + + C + GQC +C+ G +C+RCA G+Y A
Sbjct: 942 -LDSGHGCRPCNCSVAGS---VSDGCTD-EGQC-HCVPGVAGKRCDRCAHGFY--AYQDG 993
Query: 237 NCAVCNC--GGGPCDSVTGECLEEGFEPPTGCDKC 269
+C C+C CD TGEC+ C++C
Sbjct: 994 SCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEEC 1028
Score = 90.5 bits (223), Expect = 1e-17
Identities = 59/197 (29%), Positives = 83/197 (42%), Gaps = 43/197 (21%)
Query: 79 CVPCDCNGNSNEC------------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGD 120
C C+C+ + +C G G C++C +NT G +CE C+DGY
Sbjct: 324 CEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRP 383
Query: 121 SIRGAPQFCQPC-PCPLPHLANFAESCYR-------KNGAV--RCICNENYAGPNCERCA 170
+ +P +PC PC + + + C + NG +C C E Y G C+RC
Sbjct: 384 H-KVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQ 442
Query: 171 PGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDE-VTGQCRNCLRNTTGFKCERCAPGYY 229
GY P TC C C N + DE TG C C N G C+RC PG+Y
Sbjct: 443 LGYKDYP-----TCVSCGC------NPVGSASDEPCTGPC-VCKENVEGKACDRCKPGFY 490
Query: 230 G-DARIAKNCAVCNCGG 245
+ + C+ C C G
Sbjct: 491 NLKEKNPRGCSECFCFG 507
Score = 90.5 bits (223), Expect = 1e-17
Identities = 62/188 (32%), Positives = 78/188 (41%), Gaps = 21/188 (11%)
Query: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
++C GF+ G C PCDC N C +G CV C +T G CE+C DG+ G
Sbjct: 981 DRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECV-CPPHTQGVKCEECEDGHWG---YD 1036
Query: 125 APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
A CQ C C L + + C G C C + G C++C+ GY P C
Sbjct: 1037 AEVGCQACNCSL--VGSTHHRCDVVTG--HCQCKSKFGGRACDQCSLGYRDFP-----DC 1087
Query: 185 KKCDCS--GNSDPNLIFED----CDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKN 237
CDC G S E C E TG C C N G +C C G + A
Sbjct: 1088 VPCDCDLRGTSGDACNLEQGLCGCVEETGAC-PCKENVFGPQCNECREGTFALRADNPLG 1146
Query: 238 CAVCNCGG 245
C+ C C G
Sbjct: 1147 CSPCFCSG 1154
Score = 73.2 bits (178), Expect = 2e-12
Identities = 64/227 (28%), Positives = 87/227 (38%), Gaps = 50/227 (22%)
Query: 82 CDCNGNSNEC-LDGSGYCVHCQ--RNTTGEHCEKCLDGYIGDSIR----GAPQFCQPCPC 134
C C G+++ C D + + CQ NT GE C +C GY R + C+ C C
Sbjct: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329
Query: 135 PLPHLANFAESCYR-----------------KNGAVRCICNENYAGPNCERCAPGYYGNP 177
N A+ CY + G V C +N G NCE C GYY P
Sbjct: 330 -----HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYY-RP 383
Query: 178 LLIG----STCKKCDCS--GNSDPNLIFEDC------DEVTGQCRNCLRNTTGFKCERCA 225
+ C+ C+C G+ I +D + GQC C TG KC+RC
Sbjct: 384 HKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQC-PCKEGYTGEKCDRCQ 442
Query: 226 PGYYGDARIAKNCAVCNC---GGGPCDSVTGECLEEGFEPPTGCDKC 269
GY + C C C G + TG C+ + CD+C
Sbjct: 443 LGY----KDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACDRC 485
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 171 bits (434), Expect = 5e-42
Identities = 100/280 (35%), Positives = 137/280 (48%), Gaps = 34/280 (12%)
Query: 21 CSRAASGD-----DNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTL 75
C+R A G P + +V P T + G ++C G H
Sbjct: 803 CNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPG--HWG 860
Query: 76 SGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP 135
C PC CNG++++C +G C++CQ T G +CE+CL GY GD I G+ C+PCPCP
Sbjct: 861 FPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCP 920
Query: 136 --LPHLANFAESCYRKNGAVR--CICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSG 191
FA SCY+ ++ C+C+ Y G C+ CA GY+GNP +G +C+ C C
Sbjct: 921 DGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHN 980
Query: 192 N---SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNC--AVCN---- 242
N +DP E CD+ TG+C CL +T G C+ C GYYGDA + ++C VCN
Sbjct: 981 NIDTTDP----EACDKETGRCLKCLYHTEGEHCQFCRFGYYGDA-LQQDCRKCVCNYLGT 1035
Query: 243 ----CGGG--PCDSVTGECLEEGFEPPTGCDKC---VWDL 273
C G CD TG+CL CD+C W L
Sbjct: 1036 VQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQL 1075
Score = 142 bits (359), Expect = 2e-33
Identities = 180/820 (21%), Positives = 328/820 (40%), Gaps = 120/820 (14%)
Query: 58 GRLPPAAEKCNAGFFHTLS---GECVPCDCNGNSNE-----CLDGSGYCVHCQRNTTGEH 109
G + + C +G+F S G C PC C+ N + C +G C+ C +T GEH
Sbjct: 949 GYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEH 1008
Query: 110 CEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKN-----GAVRCICNENYAGP 164
C+ C GY GD+++ Q C+ C C +L E C + +C+C N G
Sbjct: 1009 CQFCRFGYYGDALQ---QDCRKCVCN--YLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQ 1063
Query: 165 NCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
NC+RCAP + L G+ C C+C+ + C+E TGQC+ C+ G C C
Sbjct: 1064 NCDRCAPNTW--QLASGTGCDPCNCNA---AHSFGPSCNEFTGQCQ-CMPGFGGRTCSEC 1117
Query: 225 APGYYGDARIAKNCAVCNCGGG-----PCDSVTGECL-EEGFEPPTGCDKCVWDLTDALR 278
++GD + C C+C CD TG+C+ EG E P CDKC
Sbjct: 1118 QELFWGDPDV--ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPR-CDKCT-------- 1166
Query: 279 LAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYA--LRKIQINNAE 336
G SGV + ++ A ++ +L+ R +++ + ++I+
Sbjct: 1167 -------RGYSGVFPDCTPC------HQCFALWDVIIAELTNRTHRFLEKAKALKISGVI 1213
Query: 337 NTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKML 396
+ + VE V + K L Q + + + + L E+A + + E+ ++
Sbjct: 1214 GPYRETVDSVERKVSEI-----KDILAQSPAAEPLKNIGNLFEEAEKLIKDVTEMMAQV- 1267
Query: 397 YYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVD---EEADEAYELLSQAESW 453
++S+ + +E+ S Q T+ E +D +E E E + ++
Sbjct: 1268 ---------EVKLSDTTSQSNSTAKELDSLQ---TEAESLDNTVKELAEQLEFIKNSDIR 1315
Query: 454 QRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQ 513
L + T+ F + LE + NA ++ ++Q+ ED+ ++ ++ +++Q
Sbjct: 1316 GALDSITK-YFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQ 1374
Query: 514 ERVREQM--EVVNMSLSTSADSL--TTPRLTLSELDDIIKNASGIYAEID-GAKSELQVK 568
R+ +++ ++ ++ LS +A+ T P + SE + G D G +
Sbjct: 1375 ARLLDELAGKLQSLDLSAAAEMTCGTPPGASCSETE-----CGGPNCRTDEGERKCGGPG 1429
Query: 569 LSNLSNLSHDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVS 628
L ++H+ Q+A+D QD+ L A E + VS
Sbjct: 1430 CGGLVTVAHNAWQKAMDLDQDV-----------------------LSALAEVEQLSKMVS 1466
Query: 629 EANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQAREL--QAKAESSSDEAVAD 686
EA A+ A + + I + ++ +E NL+ Q R Q A+ S EAVA+
Sbjct: 1467 EAKLRADEAKQSAEDILLKTNATKEKMDKSNEELRNLIKQIRNFLTQDSADLDSIEAVAN 1526
Query: 687 --TSRRVGGALARKSALKTRLSDAVKQLQAAE--RGDAQQRLGQSRLITEEANRTTMEVQ 742
+ + L + + V+ L E + + ++ ++ EEA R +
Sbjct: 1527 EVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASKSAT 1586
Query: 743 --QATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTV-EQKR 799
+ TA M ++ Q A A + LT + + T+ +
Sbjct: 1587 DVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLFNASQ 1646
Query: 800 PASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEV 839
S + +++ ++ AQ A I+ + QSA +V
Sbjct: 1647 RISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDV 1686
Score = 113 bits (282), Expect = 2e-24
Identities = 62/174 (35%), Positives = 81/174 (46%), Gaps = 21/174 (12%)
Query: 76 SGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP 135
+G CD G+ + D +G C+ N G C +C G G P C+PC C
Sbjct: 769 TGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFG----FGPSGCKPCECH 824
Query: 136 LPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDP 195
L N C G +C C + C+RC PG++G P +C+ C C+G++D
Sbjct: 825 LQGSVN--AFCNPVTG--QCHCFQGVYARQCDRCLPGHWGFP-----SCQPCQCNGHAD- 874
Query: 196 NLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAK--NCAVCNCGGGP 247
DCD VTG+C NC T G CERC GYYGD I +C C C GP
Sbjct: 875 -----DCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGP 923
Score = 93.6 bits (231), Expect = 2e-18
Identities = 77/241 (31%), Positives = 110/241 (45%), Gaps = 52/241 (21%)
Query: 82 CDCNGNSNEC--LDG---------SGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP---- 126
C C G+++EC +DG G+C+ C+ NT G +CE C+D Y R A
Sbjct: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
Query: 127 QFCQPCPCPLPHLA-NFAESCY----RKNGAVRCICNENYAGPNCERCAPGYYGNP---L 178
C+ C C ++ +F + Y +G V C N G NCE+C P YY +P +
Sbjct: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDI 389
Query: 179 LIGSTCKKCDC--SGNSDPNLIFEDCDEVT--------GQCRNCLRNTTGFKCERCAPGY 228
+ C++C C +G+ + + CD T GQCR C N G C+ C G+
Sbjct: 390 RDPNFCERCTCDPAGSQNEGI----CDSYTDFSTGLIAGQCR-CKLNVEGEHCDVCKEGF 444
Query: 229 YG----DARIAKNCAVCN-----CGGGPCDSVTGECLEEGFEPPTGCDKCV---WDLTDA 276
Y D K+CA CN GG PCDS TG C + CD+C+ W L++
Sbjct: 445 YDLSSEDPFGCKSCA-CNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSND 503
Query: 277 L 277
L
Sbjct: 504 L 504
Score = 83.2 bits (204), Expect = 2e-15
Identities = 62/205 (30%), Positives = 83/205 (40%), Gaps = 29/205 (14%)
Query: 76 SGECVPCDCNGNSNEC-LD----------GSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
S C C+CN +S C D G C CQ NT G +CE+C Y R
Sbjct: 329 SNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERD 388
Query: 125 A--PQFCQPCPCPLPHLANFAESCYRKNG------AVRCICNENYAGPNCERCAPGYYGN 176
P FC+ C C P + C A +C C N G +C+ C G+Y
Sbjct: 389 IRDPNFCERCTCD-PAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDL 447
Query: 177 PLLIGSTCKKCDCSG-NSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
CK C C+ + P CD TG C C R TG C++C P ++G +
Sbjct: 448 SSEDPFGCKSCACNPLGTIPG--GNPCDSETGHCY-CKRLVTGQHCDQCLPEHWGLSNDL 504
Query: 236 KNCAVCNC--GG---GPCDSVTGEC 255
C C+C GG C + +G+C
Sbjct: 505 DGCRPCDCDLGGALNNSCFAESGQC 529
Score = 82.8 bits (203), Expect = 3e-15
Identities = 44/120 (36%), Positives = 60/120 (50%), Gaps = 14/120 (11%)
Query: 154 RCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCL 213
+C C N G C RCAPG +G S CK C+C N C+ VTGQC +C
Sbjct: 791 QCQCRPNVVGRTCNRCAPGTFG---FGPSGCKPCECHLQGSVNAF---CNPVTGQC-HCF 843
Query: 214 RNTTGFKCERCAPGYYGDARIAKNCAVCNCGG--GPCDSVTGECLE-EGFEPPTGCDKCV 270
+ +C+RC PG++G +C C C G CD VTGECL + + C++C+
Sbjct: 844 QGVYARQCDRCLPGHWG----FPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCL 899
Score = 68.6 bits (166), Expect = 5e-11
Identities = 50/161 (31%), Positives = 69/161 (42%), Gaps = 25/161 (15%)
Query: 82 CDCNGNSNECLDGS----------GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQP 131
CD G+ NE + S G C C+ N GEHC+ C +G+ D P C+
Sbjct: 400 CDPAGSQNEGICDSYTDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFY-DLSSEDPFGCKS 457
Query: 132 CPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG--NPLLIGSTCKKCD 188
C C PL + C + G C C G +C++C P ++G N L C+ CD
Sbjct: 458 CACNPLGTIPG-GNPCDSETG--HCYCKRLVTGQHCDQCLPEHWGLSNDL---DGCRPCD 511
Query: 189 CSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
C N C +GQC +C + G +C PGYY
Sbjct: 512 CDLGGALN---NSCFAESGQC-SCRPHMIGRQCNEVEPGYY 548
Score = 67.0 bits (162), Expect = 2e-10
Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 15/116 (12%)
Query: 67 CNAGFFHTLSGE---CVPCDCNG-----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYI 118
C GF+ S + C C CN N C +G+C +C+R TG+HC++CL +
Sbjct: 440 CKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHC-YCKRLVTGQHCDQCLPEHW 498
Query: 119 GDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
G + C+PC C L N SC+ ++G +C C + G C PGYY
Sbjct: 499 G--LSNDLDGCRPCDCDLGGALN--NSCFAESG--QCSCRPHMIGRQCNEVEPGYY 548
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 164 bits (416), Expect = 6e-40
Identities = 91/233 (39%), Positives = 121/233 (51%), Gaps = 33/233 (14%)
Query: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
++C AG+F S C PC CN + C +G C +C TTG +CE+C+DGY G+ G
Sbjct: 848 DRCLAGYFGFPS--CHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSG 905
Query: 125 APQFCQPCPCPLPHLAN--FAESCYRK--NGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
P C+PC CP +N FA SCY+ + V C C + Y G C C+ G+YGNP +
Sbjct: 906 QP--CRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRIS 963
Query: 181 GSTCKKCDCSGN---SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN 237
G+ C+ C C+ N +DP E C VTG+C CL NT G C+ C PG+YG A + +
Sbjct: 964 GAPCQPCACNNNIDVTDP----ESCSRVTGECLRCLHNTQGANCQLCKPGHYGSA-LNQT 1018
Query: 238 CAVCNC------------GGGP--CDSVTGECLEEGFEPPTGCDKCV---WDL 273
C C+C GGG CD VTG C CD+C W+L
Sbjct: 1019 CRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNL 1071
Score = 109 bits (273), Expect = 2e-23
Identities = 66/201 (32%), Positives = 88/201 (43%), Gaps = 28/201 (13%)
Query: 79 CVPCDCNGNSNEC------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIR--G 124
C C CN +S+ C L G G C CQ NT G+HC++C + D ++
Sbjct: 329 CRSCSCNSHSSRCHFDMTTYLASGGLSG-GVCEDCQHNTEGQHCDRCRPLFYRDPLKTIS 387
Query: 125 APQFCQPCPCPLPHLANFAESCYRKNGAV-----RCICNENYAGPNCERCAPGYYGNPLL 179
P C PC C + + A+ +C+C EN G C++C P +YG
Sbjct: 388 DPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSAT 447
Query: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCA 239
C+ CDC N +L F CD TGQC CL TG CE C GY+G C+
Sbjct: 448 DPLGCQPCDC--NPLGSLPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWGLGNHLHGCS 504
Query: 240 VCNC--GG---GPCDSVTGEC 255
C+C GG C G+C
Sbjct: 505 PCDCDIGGAYSNVCSPKNGQC 525
Score = 91.3 bits (225), Expect = 8e-18
Identities = 76/243 (31%), Positives = 103/243 (42%), Gaps = 54/243 (22%)
Query: 82 CDCNGNSNEC-----LDGS---------GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQ 127
C CNG+++EC + G G CV CQ NT G +CE+C D + R A
Sbjct: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAPWRPAAD 323
Query: 128 F----CQPCPC-PLPHLANFAESCYRKNGAVR---C-ICNENYAGPNCERCAPGYYGNPL 178
C+ C C +F + Y +G + C C N G +C+RC P +Y +PL
Sbjct: 324 LQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPL 383
Query: 179 LIGS---TCKKCDCS-----------GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
S C C+C +SDP L V GQC C N G KC++C
Sbjct: 384 KTISDPYACIPCECDPDGTISGGICVSHSDPAL-----GSVAGQCL-CKENVEGAKCDQC 437
Query: 225 APGYYG-DARIAKNCAVCNC---GGGP---CDSVTGECLEEGFEPPTGCDKCV---WDLT 274
P +YG A C C+C G P CD TG+CL + C++C W L
Sbjct: 438 KPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLG 497
Query: 275 DAL 277
+ L
Sbjct: 498 NHL 500
Score = 90.5 bits (223), Expect = 1e-17
Identities = 61/192 (31%), Positives = 78/192 (40%), Gaps = 25/192 (13%)
Query: 60 LPPAAEKCNAGFFHTLSGECVPCDCNGNSN---ECLDGSGYCVHCQRNTTGEHCEKCLDG 116
LP A E+ L V C C+ + C G C C+ G C++C G
Sbjct: 747 LPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQC-QCKPLVVGRCCDRCSTG 805
Query: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAES-CYRKNGAVRCICNENYAGPNCERCAPGYYG 175
G C PC C H ++ C + G +C C+ +G C+RC GY+G
Sbjct: 806 SYDLGHHG----CHPCHC---HPQGSKDTVCDQVTG--QCPCHGEVSGRRCDRCLAGYFG 856
Query: 176 NPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
P +C C C N E CD TG C NC TTG CERC GYYG+
Sbjct: 857 FP-----SCHPCPC------NRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSG 905
Query: 236 KNCAVCNCGGGP 247
+ C C C P
Sbjct: 906 QPCRPCLCPDDP 917
Score = 85.1 bits (209), Expect = 6e-16
Identities = 58/187 (31%), Positives = 81/187 (43%), Gaps = 26/187 (13%)
Query: 67 CNAGFFHT-LSGECVPCDCNGNS---NECLDGSGYCV--------HCQRNTTGEHCEKCL 114
C G + + L+ C C C+ + EC G G C+ C N TG C++C
Sbjct: 1006 CKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCA 1065
Query: 115 DGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
DGY + + G + CQ C C P + + C + G +C C Y G C C YY
Sbjct: 1066 DGY-WNLVPG--RGCQSCDCD-PRTSQ-SSHCDQLTG--QCPCKLGYGGKRCSECQENYY 1118
Query: 175 GNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARI 234
G+P C CDC+ I CD TG CR C +G +C+RCA G+ +
Sbjct: 1119 GDP---PGRCIPCDCNRAGTQKPI---CDPDTGMCR-CREGVSGQRCDRCARGHSQEFPT 1171
Query: 235 AKNCAVC 241
C +C
Sbjct: 1172 CLQCHLC 1178
Score = 67.0 bits (162), Expect = 2e-10
Identities = 49/155 (31%), Positives = 65/155 (41%), Gaps = 21/155 (13%)
Query: 36 IEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNA------GFFHTLSGECVPCDCNGNSN 89
I G V DP S L + KC+ G T C PCDCN +
Sbjct: 403 ISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGS 462
Query: 90 ----ECLDGSGYCVHCQRNTTGEHCEKCLDGY--IGDSIRGAPQFCQPCPCPLPHLANFA 143
C +G C+ C TG HCE+C GY +G+ + G C PC C + ++
Sbjct: 463 LPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWGLGNHLHG----CSPCDCDIG--GAYS 515
Query: 144 ESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
C KNG +C C + G +C APGY+ PL
Sbjct: 516 NVCSPKNG--QCECRPHVTGRSCSEPAPGYFFAPL 548
Score = 66.2 bits (160), Expect = 3e-10
Identities = 52/191 (27%), Positives = 71/191 (37%), Gaps = 46/191 (24%)
Query: 154 RCICNENYAGPNCERCAPGYYGNPL-----LIGSTCKKCDCSGNS-----DPNLIFEDCD 203
+C+C N GPNCERC + P L + C+ C C+ +S D
Sbjct: 294 QCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGG 353
Query: 204 EVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN----CAVCNC------GGGPC----- 248
G C +C NT G C+RC P +Y D + C C C GG C
Sbjct: 354 LSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSD 413
Query: 249 ---DSVTGECL-EEGFE-----------------PPTGCDKCVWDLTDALRLAALSIEEG 287
SV G+CL +E E P GC C + +L ++ G
Sbjct: 414 PALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTG 473
Query: 288 KSGVLSVSSGA 298
+ LS +GA
Sbjct: 474 QCLCLSYVTGA 484
Score = 45.8 bits (107), Expect = 4e-04
Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 10/107 (9%)
Query: 20 ACSRAASGDDNAFP------FDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFH 73
AC R A G N P D + ++ T + LG +C ++
Sbjct: 1060 ACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYG 1119
Query: 74 TLSGECVPCDCNGNSNE---CLDGSGYCVHCQRNTTGEHCEKCLDGY 117
G C+PCDCN + C +G C C+ +G+ C++C G+
Sbjct: 1120 DPPGRCIPCDCNRAGTQKPICDPDTGMC-RCREGVSGQRCDRCARGH 1165
Score = 42.4 bits (98), Expect = 0.004
Identities = 28/95 (29%), Positives = 39/95 (41%), Gaps = 13/95 (13%)
Query: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
G+ KC G+ + C + GQC+ C G C+RC+ G Y C
Sbjct: 765 GAVACKCHPQGS-----VGSSCSRLGGQCQ-CKPLVVGRCCDRCSTGSYDLGH--HGCHP 816
Query: 241 CNCG-----GGPCDSVTGECLEEGFEPPTGCDKCV 270
C+C CD VTG+C G CD+C+
Sbjct: 817 CHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCL 851
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 159 bits (401), Expect = 3e-38
Identities = 191/849 (22%), Positives = 329/849 (38%), Gaps = 180/849 (21%)
Query: 79 CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP--- 135
CV C CNG+S C +G C +C+ NT G HCEKC DGY GDS G CQPCPCP
Sbjct: 721 CVLCACNGHSETCDPETGVC-NCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGS 779
Query: 136 ----LPHLANFA-------------ESC--------YRKNGAVR----CICNENY----- 161
+P E C +NG VR C C++N
Sbjct: 780 SCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAV 839
Query: 162 -----------------AGPNCERCAPGYYGNPLLIGST--CKKCDCS--GNSDPNLIFE 200
AG C+RC G++GNPL CK C+C+ G
Sbjct: 840 GNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQ---S 896
Query: 201 DCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC-----GGGPCDSVTGEC 255
C+ VTGQC CL + TG C C PG+Y + + + C C+C G CD TG+C
Sbjct: 897 SCNPVTGQCE-CLPHVTGQDCGACDPGFY-NLQSGQGCERCDCHALGSTNGQCDIRTGQC 954
Query: 256 LEE----------------GFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAA 299
+ GF P GC C D +LS++ G G
Sbjct: 955 ECQPGITGQHCERCEVNHFGF-GPEGCKPC-----DCHPEGSLSLQCKDDGRCECREGFV 1008
Query: 300 AHR---------------HVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLS 344
+R E A L+K K+++ ++++ E+ + +L +
Sbjct: 1009 GNRCDQCEENYFYNRSWPGCQECPACYRLVKDKVAD-------HRVKLQELESLIANLGT 1061
Query: 345 DVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHEL 404
E + ++ + K ++E MD + A + + ++ D++Q +NN + +
Sbjct: 1062 GDEMVTDQAFEDRLKE--AEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQN 1119
Query: 405 SPKEISEKLVLAQKMLEEIRSRQPF--FTQRELVDEEADEAYELLSQAES------WQRL 456
I E LA++ + + + REL + A ++Q ES L
Sbjct: 1120 IRNTIEETGNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLL 1179
Query: 457 HNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVR-----------DAEDMNRATAAR 505
E R L ++ DD + +A N + + E++NR
Sbjct: 1180 AEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQA 1239
Query: 506 Q---RDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDD--IIKNASGIYAEIDG 560
+ +D EKQ RV E+ + A + LS LD + A+ I E +
Sbjct: 1240 KNISQDLEKQAARVHEEAK----RAGDKAVEIYASVAQLSPLDSETLENEANNIKMEAEN 1295
Query: 561 AKSELQVKLSNLSNLSHDL------VQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKAL 614
+ + KL + +L D+ V+ ++ + QQ A++L + ++ KAL
Sbjct: 1296 LEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAA-------KAL 1348
Query: 615 DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQA 674
EA + L + I + + D ++ +K +E L + +
Sbjct: 1349 ------------AEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAIN- 1395
Query: 675 KAESSSDEAVADTSRRVGGALARKSALKT------RLSDAVKQLQAAERGDAQQRLGQSR 728
+ + ++E + + +G A A + K R++ AV++ + + +A++ +
Sbjct: 1396 QTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVT 1455
Query: 729 LITEEANRTTMEVQQATAPMANNLTNWSQNLQ---HFDSSAYNTAVNS--ARDAVRNLTE 783
+ E N ++Q+A + + Q++ +A +N+ A+++V +L
Sbjct: 1456 DLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLLS 1515
Query: 784 VVPQLLDQL 792
++ LL+QL
Sbjct: 1516 IINDLLEQL 1524
Score = 115 bits (289), Expect = 3e-25
Identities = 62/181 (34%), Positives = 88/181 (48%), Gaps = 28/181 (15%)
Query: 76 SGECVPCDCNGNSNECL---------DGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
+ EC+PCDCNG S EC G+C +CQ NT G HCE+C + + G
Sbjct: 336 ASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFR---LGNN 392
Query: 127 QFCQPCPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCK 185
+ C C C P+ L+ +S RC C G C+RC PG++ L + C+
Sbjct: 393 EACSSCHCSPVGSLSTQCDS------YGRCSCKPGVMGDKCDRCQPGFHS---LTEAGCR 443
Query: 186 KCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCG 244
C C DP+ ++C+ TG+C C N GF CERC PG++ ++ + C C C
Sbjct: 444 PCSC----DPSGSIDECNIETGRC-VCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCF 498
Query: 245 G 245
G
Sbjct: 499 G 499
Score = 103 bits (257), Expect = 2e-21
Identities = 65/187 (34%), Positives = 88/187 (47%), Gaps = 32/187 (17%)
Query: 101 CQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNEN 160
C G+ CE CL GY R P PC L +E+C + G C C +N
Sbjct: 692 CPVGYGGQFCEMCLSGY----RRETPNLGPYSPCVLCACNGHSETCDPETGV--CNCRDN 745
Query: 161 YAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGF 219
AGP+CE+C+ GYYG+ S C+ C C G S ++ + + V C NC TTG
Sbjct: 746 TAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVV---CTNCPTGTTGK 802
Query: 220 KCERCAPGYYGDARIAKN-----CAVCNCGG-------GPCDSVTGECLE-----EGFEP 262
+CE C GY+GD + +N C +C C G C+ +TGECL+ GF
Sbjct: 803 RCELCDDGYFGDP-LGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFY- 860
Query: 263 PTGCDKC 269
CD+C
Sbjct: 861 ---CDRC 864
Score = 96.7 bits (239), Expect = 2e-19
Identities = 159/821 (19%), Positives = 312/821 (38%), Gaps = 152/821 (18%)
Query: 67 CNAGFFHTLSGE-CVPCDCN--GNSN-ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 122
C+ GF++ SG+ C CDC+ G++N +C +G C CQ TG+HCE+C + G
Sbjct: 919 CDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQC-ECQPGITGQHCERCEVNHFG--- 974
Query: 123 RGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGS 182
P+ C+PC C H + +G RC C E + G C++C Y+ N G
Sbjct: 975 -FGPEGCKPCDC---HPEGSLSLQCKDDG--RCECREGFVGNRCDQCEENYFYNRSWPG- 1027
Query: 183 TCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARI---AKNCA 239
C++C C R D R+
Sbjct: 1028 -CQECPA-------------------------------CYRLVKDKVADHRVKLQELESL 1055
Query: 240 VCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAA 299
+ N G G + VT + E+ + + ++ D LR A +++ ++
Sbjct: 1056 IANLGTGD-EMVTDQAFEDRLK------EAEREVMDLLR-EAQDVKDVDQNLMD-----R 1102
Query: 300 AHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRK 359
R N +++ I L+ + E L + + ENT + L+ +EK A+
Sbjct: 1103 LQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVENT-ERLIEIASRELEKAKVAAAN 1161
Query: 360 GQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKM 419
+ Q ES N+ + L E+A + ++ ++ + ++ + + E L
Sbjct: 1162 VSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLL------ 1215
Query: 420 LEEIRSRQPFFTQRELVDEEADEAYELLSQAESW-QRLHNETRTLFPVVLEQLDDYNAKL 478
L + + E ++ + ++A + E R+H E + +E A+L
Sbjct: 1216 LRTLAGENQTAFEIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASV-AQL 1274
Query: 479 SDL-QEALDQALNYVR-DAEDMNRATAARQRDHEKQQERVR-EQMEVVNMSLSTSADSLT 535
S L E L+ N ++ +AE++ + + +D+E +E +R +++EV N+ + T
Sbjct: 1275 SPLDSETLENEANNIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQT 1334
Query: 536 TPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEAN 595
A + A D AK+ L +EA +D QEAN
Sbjct: 1335 ---------------ADQLLARADAAKA---------------LAEEAAKKGRDTLQEAN 1364
Query: 596 ELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQI 655
++ L D ++ D E + + N+T A T A+
Sbjct: 1365 DILNNLKDFD-----RRVNDNKTAAEEALRKIPAINQTITEANEKTREAQQALGSAAAD- 1418
Query: 656 IYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAA 715
E++N ++A + + + ++ A+ R A + L +++ +KQLQ A
Sbjct: 1419 ---ATEAKNKAHEAERIASAVQKNATSTKAEAER----TFAEVTDLDNEVNNMLKQLQEA 1471
Query: 716 ER------GDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNT 769
E+ DA Q + + + ++ A + ++A
Sbjct: 1472 EKELKRKQDDADQDMMMAGMASQAAQEAEINARKA-----------------------KN 1508
Query: 770 AVNSARDAVRNLTEVVPQL----LDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKI 825
+V S + +L E + QL L++L +E + + + ++ + A K
Sbjct: 1509 SVTSLLSIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAKKQ 1568
Query: 826 QVSMMFDGQSAVEV-HSRTSMDDLKAFTSLSLYMKPPVKRP 865
+ ++M + E+ +++D++ + P +++P
Sbjct: 1569 EAAIMDYNRDIEEIMKDIRNLEDIRKTLPSGCFNTPSIEKP 1609
Score = 82.8 bits (203), Expect = 3e-15
Identities = 73/266 (27%), Positives = 109/266 (40%), Gaps = 38/266 (14%)
Query: 27 GDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAE------KCNAGFFHTLSGECV 80
G +A+ FD ++ Q+ ++ RV L RL + K +++ +S V
Sbjct: 227 GRPSAYNFD----NSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAV 282
Query: 81 P--CDCNGNSNECLDGS--GYCVHCQRNTTGEHCEKCLDGYIGDSIRGA----PQFCQPC 132
C CNG+++EC+ +C+ NT G CEKCL + R A C PC
Sbjct: 283 GGRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPC 342
Query: 133 PC-PLPHLANFAESCYRKNG-AVRCI-CNENYAGPNCERCAPGYY--GNPLLIGSTCKKC 187
C F YR G C C +N G +CERC ++ GN C C
Sbjct: 343 DCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGN----NEACSSC 398
Query: 188 DCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG- 246
C S + CD G+C +C G KC+RC PG++ + C C+C
Sbjct: 399 HC---SPVGSLSTQCDSY-GRC-SCKPGVMGDKCDRCQPGFH--SLTEAGCRPCSCDPSG 451
Query: 247 ---PCDSVTGECLEEGFEPPTGCDKC 269
C+ TG C+ + C++C
Sbjct: 452 SIDECNIETGRCVCKDNVEGFNCERC 477
Score = 75.1 bits (183), Expect = 6e-13
Identities = 43/107 (40%), Positives = 52/107 (48%), Gaps = 11/107 (10%)
Query: 155 CICNENYAGPNCERCAPGYYGNPLLIG--STCKKCDCSGNSDPNLIFEDCDEVTGQCRNC 212
C C Y G CE C GY +G S C C C+G+S E CD TG C NC
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHS------ETCDPETGVC-NC 742
Query: 213 LRNTTGFKCERCAPGYYGD--ARIAKNCAVCNCGGGPCDSVTGECLE 257
NT G CE+C+ GYYGD A + +C C C GG +V + E
Sbjct: 743 RDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKE 789
Score = 37.0 bits (84), Expect = 0.18
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 3/44 (6%)
Query: 65 EKCNAGFFHTLSGE---CVPCDCNGNSNECLDGSGYCVHCQRNT 105
E+C GFF+ S C PC C G+S+ C + GY V+ +T
Sbjct: 475 ERCKPGFFNLESSNPRGCTPCFCFGHSSVCTNAVGYSVYSISST 518
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 159 bits (401), Expect = 3e-38
Identities = 83/216 (38%), Positives = 115/216 (53%), Gaps = 22/216 (10%)
Query: 79 CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP--L 136
C PC CNG+++EC +G C+ C+ +T GEHCE+C+ G+ GD C+PCPCP
Sbjct: 874 CRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGP 933
Query: 137 PHLANFAESCYRK--NGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSD 194
+FA SC++ + + C C Y G CE CAPG++G+P G C+ C+CSGN D
Sbjct: 934 GSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNID 993
Query: 195 PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC---GGGP---- 247
P + + CD TGQC CL +T G C C PG++G A ++C C C G P
Sbjct: 994 P-MDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQA-ARQSCHRCTCNLLGTNPQQCP 1051
Query: 248 ------CDSVTGECLEEGFEPPTGCDKCV---WDLT 274
CD +G+C CD+C W+LT
Sbjct: 1052 SPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLT 1087
Score = 113 bits (283), Expect = 1e-24
Identities = 187/837 (22%), Positives = 311/837 (37%), Gaps = 131/837 (15%)
Query: 65 EKCNAGFFHTLS---GECVPCDCNGN-----SNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
E C G F S G C C+C+GN + C +G C+ C +T G HC C G
Sbjct: 966 EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPG 1025
Query: 117 YIGDSIRGAPQFCQPCPCPL----PHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172
+ G + R Q C C C L P + C+ + +C C N GP+C+RCAP
Sbjct: 1026 FHGQAAR---QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPN 1082
Query: 173 YYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA 232
++ L G C+ C C + C+E TGQC +C G C C ++GD
Sbjct: 1083 FWN--LTSGHGCQPCACHPSRARG---PTCNEFTGQC-HCRAGFGGRTCSECQELHWGDP 1136
Query: 233 RIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEG 287
+ C C+C C TG C CD+C G
Sbjct: 1137 GL--QCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCA---------------RG 1179
Query: 288 KSGVLSVSSGAAA-----HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSL 342
SG+ A R V ++ A L+ + E + L + ++ M+
Sbjct: 1180 FSGIFPACHPCHACFGDWDRVVQDLAARTQRLEQRAQELQQTGVLGAFE--SSFWHMQEK 1237
Query: 343 LSDVEELVEKEN-QASRKGQLVQ------KESMDTINHASQLVEQAHDMRDKIQEINNKM 395
L V+ +V N A+ QLV+ +E + H +QL D++D+ N+ +
Sbjct: 1238 LGIVQGIVGARNTSAASTAQLVEATEELRREIGEATEHLTQLEADLTDVQDENFNANHAL 1297
Query: 396 LYYGEEH---ELSPKEISEKLVLAQ--KMLEEIRSRQPFFTQRELVDEEAD-EAYELLSQ 449
+ L+ +++ + L L + L S + +Q + A+ A + S
Sbjct: 1298 SGLERDRLALNLTLRQLDQHLDLLKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSP 1357
Query: 450 AESWQRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQ--ALNYVRDAEDMNRATAARQR 507
+ + T L Q +D+N+K Q AL + A + D+N
Sbjct: 1358 VSNSASARHRTEALMDA---QKEDFNSKHMANQRALGKLSAHTHTLSLTDINELVCGAPG 1414
Query: 508 DH------------EKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGI- 554
D + + R N + +T+ +L R T +EL + I
Sbjct: 1415 DAPCATSPCGGAGCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRALAEGGSIL 1474
Query: 555 --YAEIDGAKSELQVKLS---NLSNLSHDLVQEAIDHAQDLQQEANELSRKLHSSDMNGL 609
AE SE Q + + +N S V++A Q+L Q + + +D + +
Sbjct: 1475 SRVAETRRQASEAQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQ-EGADPDSI 1533
Query: 610 VQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQA 669
+ A+ V E + +E + A+ R V I + + +E LL A
Sbjct: 1534 ---EMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQDA 1590
Query: 670 RELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRL 729
R ++ AE +A + A+++ Q A+ G AQ + +
Sbjct: 1591 RRARSWAEDEKQKA-------------------ETVQAALEEAQRAQ-GIAQGAIRGAVA 1630
Query: 730 ITEEANRTTMEVQQATAPMANNLTNWSQNLQHFD-------------SSAYNTAVNSARD 776
T + +T +VQ+ A L++ + + D S A +TA +A
Sbjct: 1631 DTRDTEQTLYQVQERMAGAERALSSAGERARQLDALLEALKLKRAGNSLAASTAEETAGS 1690
Query: 777 AVRNLTEVVPQLL-----DQLRTVE--QKRPASNVSASIQRIRELIAQTRSVASKIQ 826
A + + QLL DQ +TV+ +R A V A+ R +L + R + Q
Sbjct: 1691 A-QGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAAQ 1746
Score = 103 bits (258), Expect = 1e-21
Identities = 58/173 (33%), Positives = 81/173 (46%), Gaps = 25/173 (14%)
Query: 80 VPCDCNGN---SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136
+PC CN S+EC G C+ C+ G C+ C GY G P CQ C C
Sbjct: 781 LPCQCNPQGSLSSECNPHGGQCL-CKPGVVGRRCDLCAPGYYG----FGPTGCQACQC-- 833
Query: 137 PHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPN 196
H + C + +G +C+C G C+RC G +G P +C+ C C+G++D
Sbjct: 834 SHEGALSSLCEKTSG--QCLCRTGAFGLRCDRCQRGQWGFP-----SCRPCVCNGHAD-- 884
Query: 197 LIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARI--AKNCAVCNCGGGP 247
+C+ TG C C +T G CERC G++GD R+ C C C GP
Sbjct: 885 ----ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGP 933
Score = 97.4 bits (241), Expect = 1e-19
Identities = 60/205 (29%), Positives = 88/205 (42%), Gaps = 29/205 (14%)
Query: 76 SGECVPCDCNGNSNEC--------LDGS---GYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
S C C+C+G+++ C G+ G C CQ NT G HCE C + D +
Sbjct: 341 SHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKD 400
Query: 125 A--PQFCQPCPCPLPHLANFAESCYRKNGAV------RCICNENYAGPNCERCAPGYYGN 176
P C+ C C P + C + +C C E+ G C++C G++G
Sbjct: 401 LRDPAVCRSCDCD-PMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGL 459
Query: 177 PLLIGSTCKKCDCSGNSD-PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
+ C++C C+ P CD +G C C R TG C+RC PG++G +
Sbjct: 460 SISDRLGCRRCQCNARGTVPG--STPCDPNSGSC-YCKRLVTGRGCDRCLPGHWGLSHDL 516
Query: 236 KNCAVCNCGGG-----PCDSVTGEC 255
C C+C G CD TG+C
Sbjct: 517 LGCRPCDCDVGGALDPQCDEGTGQC 541
Score = 96.7 bits (239), Expect = 2e-19
Identities = 72/235 (30%), Positives = 102/235 (43%), Gaps = 40/235 (17%)
Query: 82 CDCNGNSNECLDGSGYCVH----------CQRNTTGEHCEKCLDGYIGDSIR----GAPQ 127
C C G+++EC G H C+ NT G +CE+C D Y R G
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSH 342
Query: 128 FCQPCPCP-LPHLANFAESCYRKNGAVR---CI-CNENYAGPNCERCAPGYYGNP---LL 179
C+ C C H +F + Y +G V C C N AG +CE C P +Y +P L
Sbjct: 343 ACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLR 402
Query: 180 IGSTCKKCDCS--GNSDPNLIFEDCDE----VTGQCRNCLRNTTGFKCERCAPGYYGDAR 233
+ C+ CDC G+ D D V+GQCR C + G +C++C G++G +
Sbjct: 403 DPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCR-CKEHVVGTRCQQCRDGFFGLSI 461
Query: 234 IAK-NCAVCNC-------GGGPCDSVTGECLEEGFEPPTGCDKCV---WDLTDAL 277
+ C C C G PCD +G C + GCD+C+ W L+ L
Sbjct: 462 SDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDL 516
Score = 83.6 bits (205), Expect = 2e-15
Identities = 55/168 (32%), Positives = 79/168 (47%), Gaps = 31/168 (18%)
Query: 79 CVPCDCNGNSNECLDG--------------SGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
C CDC+ ++ DG SG C C+ + G C++C DG+ G SI
Sbjct: 407 CRSCDCDPMGSQ--DGGRCDSHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFGLSISD 463
Query: 125 APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG-NPLLIGST 183
C+ C C + C +G+ C C G C+RC PG++G + L+G
Sbjct: 464 RLG-CRRCQCNARGTVPGSTPCDPNSGS--CYCKRLVTGRGCDRCLPGHWGLSHDLLG-- 518
Query: 184 CKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
C+ CDC G DP CDE TGQC +C ++ G +CE+ PGY+
Sbjct: 519 CRPCDCDVGGALDPQ-----CDEGTGQC-HCRQHMVGRRCEQVQPGYF 560
Score = 74.3 bits (181), Expect = 1e-12
Identities = 46/144 (31%), Positives = 66/144 (45%), Gaps = 22/144 (15%)
Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGST-CKKCDCSG 191
PC + + C G +C+C G C+ CAPGYYG G T C+ C CS
Sbjct: 782 PCQCNPQGSLSSECNPHGG--QCLCKPGVVGRRCDLCAPGYYG----FGPTGCQACQCSH 835
Query: 192 NSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG--GPCD 249
+ + C++ +GQC C G +C+RC G +G +C C C G C+
Sbjct: 836 EGALSSL---CEKTSGQCL-CRTGAFGLRCDRCQRGQWG----FPSCRPCVCNGHADECN 887
Query: 250 SVTGECLEEGFEPPTG---CDKCV 270
+ TG CL G TG C++C+
Sbjct: 888 THTGACL--GCRDHTGGEHCERCI 909
Score = 58.9 bits (141), Expect = 4e-08
Identities = 38/120 (31%), Positives = 55/120 (45%), Gaps = 19/120 (15%)
Query: 65 EKCNAGFFHTLSGE---CVPCDCNGN-----SNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
++C GFF + C C CN S C SG C +C+R TG C++CL G
Sbjct: 450 QQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSC-YCKRLVTGRGCDRCLPG 508
Query: 117 YIGDS--IRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
+ G S + G C+PC C + + C G +C C ++ G CE+ PGY+
Sbjct: 509 HWGLSHDLLG----CRPCDCDVGGALD--PQC--DEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 56.2 bits (134), Expect = 3e-07
Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 18/138 (13%)
Query: 62 PAAEKCNAGFFHTLSGE-CVPCDCN---GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117
P+ ++C F++ SG C PC C+ C + +G C HC+ G C +C + +
Sbjct: 1074 PSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQC-HCRAGFGGRTCSECQELH 1132
Query: 118 IGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNP 177
GD C C C + C+R G C C +G C++CA G+ G
Sbjct: 1133 WGDP----GLQCHACDCDSRGIDT--PQCHRFTG--HCSCRPGVSGVRCDQCARGFSG-- 1182
Query: 178 LLIGSTCKKCD-CSGNSD 194
I C C C G+ D
Sbjct: 1183 --IFPACHPCHACFGDWD 1198
Score = 39.3 bits (90), Expect = 0.035
Identities = 68/328 (20%), Positives = 134/328 (40%), Gaps = 47/328 (14%)
Query: 341 SLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAH-DMRDKIQEINNKMLYYG 399
S+LS V E + ++A ++ Q ++D N + VEQA+ ++++ IQ + + + G
Sbjct: 1472 SILSRVAETRRQASEAQQRAQA----ALDKANASRGQVEQANQELQELIQSVKDFLNQEG 1527
Query: 400 EEH-----------ELSPKEISEKLV-LAQKMLEEIRSRQPF--FTQRELVD-EEADEAY 444
+ ELS +E++ LA + E +RS R + D A++
Sbjct: 1528 ADPDSIEMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLL 1587
Query: 445 ELLSQAESWQRLHNETRTLFPVVLEQLDDYN-----------AKLSDLQEALDQALNYVR 493
+ +A SW + LE+ A D ++ L Q +
Sbjct: 1588 QDARRARSWAEDEKQKAETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMA 1647
Query: 494 DAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASG 553
AE + R R + E ++ + +++ ST+ ++ + + E + +++ G
Sbjct: 1648 GAERALSSAGERARQLDALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLG 1707
Query: 554 IYAEIDGAKSE--------LQVKLSNLSNLSHDLVQEAIDHAQDLQQ-----EANELSRK 600
+ A +E Q + L + + DL+Q A D Q LQ+ E NE + +
Sbjct: 1708 DQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALE 1767
Query: 601 LHSSDMNGL---VQKALDASNVYENIVN 625
++ ++GL ++ L A N+ I N
Sbjct: 1768 SKAAQLDGLEARMRSVLQAINLQVQIYN 1795
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 145 bits (367), Expect = 3e-34
Identities = 84/224 (37%), Positives = 107/224 (47%), Gaps = 26/224 (11%)
Query: 65 EKCNAGFFHTLS-----GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
E C G+ + CVPC CN + C +G CV C +T G CE+CL G+ G
Sbjct: 685 ESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDPNTGICV-CSHHTEGPSCERCLPGFYG 742
Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPL 178
+ G CQPCPCP A + ++ V C C G CE C G++G+PL
Sbjct: 743 NPFAGQADDCQPCPCP----GQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPL 798
Query: 179 -LIG--STCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA--- 232
L G C +C CSGN DPN + +CD ++G C CL NTTG CE C G+YG A
Sbjct: 799 GLFGHPQPCHQCQCSGNVDPNAV-GNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAP 857
Query: 233 RIAKNCAVCNCGGG-------PCDSVTGECLEEGFEPPTGCDKC 269
R A C C+C PCD VTG+C C +C
Sbjct: 858 RPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRC 901
Score = 119 bits (297), Expect = 4e-26
Identities = 193/862 (22%), Positives = 320/862 (37%), Gaps = 119/862 (13%)
Query: 29 DNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPA-----AEKCNAGFFHTLSG------ 77
D+ P G SA PE+ E V PP E C+ GFF G
Sbjct: 750 DDCQPCPCPGQSAC--TTIPESRE--VVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQ 805
Query: 78 ECVPCDCNGNSN-----ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP-QFCQP 131
C C C+GN + C SG+C+ C NTTG+HCE C +G+ G ++ P C P
Sbjct: 806 PCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMP 865
Query: 132 CPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCS- 190
C C + C G +C C + +C RC PG++ L G C+ C C
Sbjct: 866 CSCHPQGSVSEQMPCDPVTG--QCSCLPHVTARDCSRCYPGFF--DLQPGRGCRSCKCHP 921
Query: 191 -GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCD 249
G+ + + C TGQC C TG C+RC G++G + K C C C P
Sbjct: 922 LGSQE-----DQCHPKTGQC-TCRPGVTGQACDRCQLGFFGFS--IKGCRACRC--SPLG 971
Query: 250 SVTGECLEE-------GFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHR 302
+ + +C E GFE CD+C D L A +G S A
Sbjct: 972 AASAQCHENGTCVCRPGFE-GYKCDRC----HDNFFLTA----DGTHCQQCPSCYALVKE 1022
Query: 303 HVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKGQL 362
++ A + L + L + + I E + L +R+ L
Sbjct: 1023 EAAKLKARLTLTEGWLQGSDCGSPWGPLDILLGEAPRGDVYQGHHLL-----PGAREAFL 1077
Query: 363 VQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEE 422
Q S++ A+ R+++Q +N + + ++++ + + EE
Sbjct: 1078 EQMMSLEGAVKAA---------REQLQRLNKGARCAQAGSQKTCTQLADLEAVLESSEEE 1128
Query: 423 IRSRQPFFTQRELVDEEADEAYE---LLSQAESWQRLHNETRT-LFPVVLEQLDDYNAKL 478
I E+ E + + L ++A + R H +T T + L N
Sbjct: 1129 ILHAAAILASLEIPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRALLASNTSY 1188
Query: 479 SDLQEALD--QALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTT 536
+ L L+ AL RD ED + A Q+ V + E V ++ + T
Sbjct: 1189 ALLWNLLEGRVALETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESV-LATVQQVGADTA 1247
Query: 537 PRLTLSELDDIIKNASGIYAEIDGAKSE-LQVKLSNLSNLSHDLVQEAIDHAQDLQQEAN 595
P L L + S AE G K++ L+ +++ +++ + + AQ ++
Sbjct: 1248 PYLALLASPGALPQKS--RAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQATLRQTE 1305
Query: 596 ELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQI 655
L+ KLH L Q S + + A + + + G+ Q
Sbjct: 1306 PLT-KLHQEARAALTQ---------------ASSSVQAATVTVMGARTLLADLEGMKLQF 1349
Query: 656 IYHKDESENLLNQARELQAKAESSSDEAVADT-------SRRVGGALARKSALKTR---- 704
KD++ LQ KA+S SD +ADT R +G A S+ K +
Sbjct: 1350 PRPKDQA--------ALQRKADSVSDRLLADTRKKTKQAERMLGNAAPLSSSAKKKGREA 1401
Query: 705 ---LSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQH 761
D+ K +A R Q SRL ++ QQ A A
Sbjct: 1402 EVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQASQQVLASEARRQELEEAERVG 1461
Query: 762 FDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVE-QKRPASNVSA---SIQRIRELIAQ 817
S + +R ++ E + +LL +L +++ + PA ++ +++R+R +
Sbjct: 1462 AGLSEMEQQIRESRISLEKDIETLSELLARLGSLDTHQAPAQALNETQWALERLRLQLGS 1521
Query: 818 TRSVASKIQVSMMFDGQSAVEV 839
S+ K+ + Q +++
Sbjct: 1522 PGSLQRKLSLLEQESQQQELQI 1543
Score = 97.4 bits (241), Expect = 1e-19
Identities = 68/201 (33%), Positives = 91/201 (45%), Gaps = 22/201 (10%)
Query: 82 CDCNGNSNEC---LDGSGYCVHCQRNTTGEHCEKCL----DGYIGDSIRGAPQFCQPCPC 134
C CNG+++EC + G C CQ NTTG CE+CL D A C PC C
Sbjct: 271 CKCNGHASECGPDVAGQLAC-RCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC 329
Query: 135 P-LPHLANFAESCYRKNG-AVRC-ICNENYAGPNCERCAPGYY-GNPLLIGSTCKKCDCS 190
F +R G RC C ++ AGP+CERC +Y +P + C+ CDC
Sbjct: 330 SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRM---PCQPCDCQ 386
Query: 191 GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG--PC 248
+L CD+ TG C C TG+KC+RC PG++ + CN G C
Sbjct: 387 SAGSLHL---QCDD-TGTCA-CKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTC 441
Query: 249 DSVTGECLEEGFEPPTGCDKC 269
D +G C + CD+C
Sbjct: 442 DPRSGRCPCKENVEGNLCDRC 462
Score = 93.2 bits (230), Expect = 2e-18
Identities = 55/178 (30%), Positives = 76/178 (42%), Gaps = 26/178 (14%)
Query: 78 ECVPCDCNGNSNECL---------DGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF 128
EC+PC+C+G S EC G C HC+ +T G HCE+C + + R
Sbjct: 323 ECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPR---MP 379
Query: 129 CQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCD 188
CQPC C + C + C C G C+RC PG++ L C+ C
Sbjct: 380 CQPCDC--QSAGSLHLQC---DDTGTCACKPTVTGWKCDRCLPGFHS---LSEGGCRPCT 431
Query: 189 CSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCGG 245
C +P + CD +G+C C N G C+RC PG + C+ C C G
Sbjct: 432 C----NPAGSLDTCDPRSGRC-PCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYG 484
Score = 66.2 bits (160), Expect = 3e-10
Identities = 42/134 (31%), Positives = 58/134 (43%), Gaps = 17/134 (12%)
Query: 151 GAVRCICNENYAGPNCERCAPGYYGNPLLIGST-----CKKCDCSGNSDPNLIFEDCDEV 205
G + C C N G +CERC P + P G+ C C+CSG S+ +
Sbjct: 286 GQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRS 345
Query: 206 T---GQCRNCLRNTTGFKCERCAPGYY-GDARIAKNCAVCNCGGG-----PCDSVTGECL 256
T G+C +C +T G CERC +Y D R+ C C+C CD TG C
Sbjct: 346 TGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--CQPCDCQSAGSLHLQCDD-TGTCA 402
Query: 257 EEGFEPPTGCDKCV 270
+ CD+C+
Sbjct: 403 CKPTVTGWKCDRCL 416
Score = 64.3 bits (155), Expect = 1e-09
Identities = 38/98 (38%), Positives = 46/98 (46%), Gaps = 18/98 (18%)
Query: 155 CICNENYAGPNCERCAPGY-----YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQC 209
C C Y G CE CAPGY G P ++C C C+ + CD TG C
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPY---ASCVPCTCNQHG-------TCDPNTGIC 722
Query: 210 RNCLRNTTGFKCERCAPGYYGD--ARIAKNCAVCNCGG 245
C +T G CERC PG+YG+ A A +C C C G
Sbjct: 723 -VCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPG 759
Score = 43.1 bits (100), Expect = 0.002
Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 65 EKCNAGFFHTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 122
++C GF G C PC CN G+ + C SG C C+ N G C++C G
Sbjct: 413 DRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGRC-PCKENVEGNLCDRCRPGTFNLQP 471
Query: 123 RGAPQFCQPCPC 134
P C C C
Sbjct: 472 HN-PAGCSSCFC 482
>gi|157419130 laminin, alpha 4 isoform 3 precursor [Homo sapiens]
Length = 120
Score = 135 bits (341), Expect = 3e-31
Identities = 65/65 (100%), Positives = 65/65 (100%)
Query: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
Sbjct: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
Query: 61 PPAAE 65
PPAAE
Sbjct: 61 PPAAE 65
>gi|157419128 laminin, alpha 4 isoform 3 precursor [Homo sapiens]
Length = 120
Score = 135 bits (341), Expect = 3e-31
Identities = 65/65 (100%), Positives = 65/65 (100%)
Query: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL
Sbjct: 1 MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRL 60
Query: 61 PPAAE 65
PPAAE
Sbjct: 61 PPAAE 65
>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
Length = 639
Score = 132 bits (331), Expect = 4e-30
Identities = 66/185 (35%), Positives = 92/185 (49%), Gaps = 14/185 (7%)
Query: 57 LGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
+G + ++C G++ C+PC CN S C +G C++CQ N+ G HCE+C +G
Sbjct: 313 VGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEG 372
Query: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNE---NYAGPNCERCAPGY 173
+ A + C CPC SC K+ + C++ Y GPNC +C GY
Sbjct: 373 FYQSP--DATKECLRCPCSA---VTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGY 427
Query: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR 233
Y S C+KC C G+ DP + C +G+C NCL NTTGF CE C GY D
Sbjct: 428 YN----FDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHD-- 481
Query: 234 IAKNC 238
+ NC
Sbjct: 482 LEGNC 486
Score = 105 bits (262), Expect = 4e-22
Identities = 66/194 (34%), Positives = 85/194 (43%), Gaps = 29/194 (14%)
Query: 82 CDCNG----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLP 137
C+C+ N N C +G C C+ G HCE C +G+ + G CQPC C P
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSG---LCQPCDCS-P 295
Query: 138 HLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNL 197
H A + C N + +C C G C+RC GYYG + C C C+ S
Sbjct: 296 HGA-LSIPC---NSSGKCQCKVGVIGSICDRCQDGYYG---FSKNGCLPCQCNNRS---- 344
Query: 198 IFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSV--TGEC 255
CD +TG C NC N+ G CE C G+Y K C C PC +V TG C
Sbjct: 345 --ASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRC-----PCSAVTSTGSC 397
Query: 256 LEEGFEPPTGCDKC 269
+ E CD+C
Sbjct: 398 SIKSSELEPECDQC 411
>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
Length = 1193
Score = 131 bits (329), Expect = 7e-30
Identities = 174/804 (21%), Positives = 315/804 (39%), Gaps = 138/804 (17%)
Query: 77 GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136
G C+PC+C G C +G C N E C C G+ D P+ C+PCPC
Sbjct: 411 GTCIPCNCQGGG-ACDPDTGDCYSGDENPDIE-CADCPIGFYNDP--HDPRSCKPCPCH- 465
Query: 137 PHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLIGST---CKKCDCSGN 192
F+ S + V C C G CE CA GY+G+P C+ C C+ N
Sbjct: 466 ---NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN 522
Query: 193 SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGD---ARIAKNCAVCNC---GGG 246
DP+ +CD +TG+C C+ NT G C++C GY+GD A C CNC G
Sbjct: 523 VDPSAS-GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581
Query: 247 P--CDSVTGECL-EEGFEPPT------GCDKCVWD--------LTDALRLAAL-SIEEGK 288
P C S G C+ + GF P C C + R+ AL S +G
Sbjct: 582 PVGCRS-DGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGG 640
Query: 289 SGVLSVSSGAAAHRHVNEINATIYLLKTKLSE-RENQYALRKIQINNAENTMKSLLSDVE 347
GV+ + + + I L ++SE L+ ++ + EN+ +S L D++
Sbjct: 641 DGVVPDTELEGRMQQAEQALQDI-LRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLK 699
Query: 348 ELVEK---------------------------ENQAS----------------------R 358
VE+ E++AS +
Sbjct: 700 MTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQ 759
Query: 359 KGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQK 418
+ + + +++ ++ QL + D + + K L+ G + + L +K
Sbjct: 760 EATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEK 819
Query: 419 MLEEIRSRQPFFTQRELVDEEADEAYE-LLSQAESWQRLHNETRTLFPVVLEQLDDYNAK 477
+ + Q + + EAD +Y+ L +S RL + F V E+ K
Sbjct: 820 LEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQV--EEAKRIKQK 877
Query: 478 LSDLQEALDQALN-YVRDAEDM-NRATAARQ--RDHEKQQERVREQMEVVNMSLSTSADS 533
L + + ++ + R +++ N A+Q ++ + +E+ + + N++ S + ++
Sbjct: 878 ADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEA 937
Query: 534 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 593
L+ T E++ I+KN ++D K+E + + LS +S V +A D Q ++
Sbjct: 938 LSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQK-VSDASDKTQQAERA 996
Query: 594 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGI-- 651
+ + NG + +S + + I + EAN TA+ AL + S +
Sbjct: 997 LGSAAADAQRA-KNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMRE 1055
Query: 652 --------DTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGAL-------- 695
+ + + D + ++ +A+++ +A+++ + DT + G L
Sbjct: 1056 VEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNAG-VTIQDTLNTLDGLLHLMDQPLS 1114
Query: 696 ----------ARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQAT 745
+ S KT+++ ++ + + A+Q+ G L+ + +V+
Sbjct: 1115 VDEEGLVLLEQKLSRAKTQINSQLRPMMSELEERARQQRGHLHLLETSIDGILADVK--- 1171
Query: 746 APMANNLTNWSQNLQHFDSSAYNT 769
NL N NL YNT
Sbjct: 1172 -----NLENIRDNL---PPGCYNT 1187
Score = 95.9 bits (237), Expect = 3e-19
Identities = 62/182 (34%), Positives = 82/182 (45%), Gaps = 36/182 (19%)
Query: 82 CDCNGNSNECL--------DGSGY-CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPC 132
CDCNG S +C+ G+G+ C++C NT G HCEKC +G+ R C PC
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR---CLPC 84
Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC-------- 184
C + R + + RC C G C+RC PG++ +L + C
Sbjct: 85 NC-----NSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH---MLTDAGCTQDQRLLD 136
Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNC 243
KCDC DP I CD G+C C TG +C+RC GYY D + C C C
Sbjct: 137 SKCDC----DPAGIAGPCD--AGRC-VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Query: 244 GG 245
G
Sbjct: 190 YG 191
Score = 73.9 bits (180), Expect = 1e-12
Identities = 49/140 (35%), Positives = 63/140 (45%), Gaps = 23/140 (16%)
Query: 65 EKCNAGFF-HTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
EKC GF+ H C+PC+CN G+ + D SG C C+ TG C++CL G+ +
Sbjct: 66 EKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRC-SCKPGVTGARCDRCLPGFHMLT 124
Query: 122 IRGAPQ----FCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY--- 174
G Q C C A A C A RC+C G C+RC GYY
Sbjct: 125 DAGCTQDQRLLDSKCDC---DPAGIAGPC----DAGRCVCKPAVTGERCDRCRSGYYNLD 177
Query: 175 -GNPLLIGSTCKKCDCSGNS 193
GNP C +C C G+S
Sbjct: 178 GGNP----EGCTQCFCYGHS 193
Score = 71.2 bits (173), Expect = 8e-12
Identities = 147/690 (21%), Positives = 246/690 (35%), Gaps = 147/690 (21%)
Query: 154 RCICNENYAGPNCERCAPGYYGNPLLIG--STCKKCDC--------------SGNSDPNL 197
+CIC Y G C+ CA GY + +G TC C+C SG+ +P++
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
Query: 198 IFEDC-------------------------------DEVTGQCRNCLRNTTGFKCERCAP 226
DC +EV C NC TG +CE CA
Sbjct: 441 ECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV--CNNCPPGVTGARCELCAD 498
Query: 227 GYYGDA----RIAKNCAVCNC-------GGGPCDSVTGECL--------------EEGF- 260
GY+GD + C C C G CD +TG CL + G+
Sbjct: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
Query: 261 -EP--PTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTK 317
+P P DKC + + + + V G H Y
Sbjct: 559 GDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAFSCPACY----- 613
Query: 318 LSERENQYALRKIQINNAENTMKSLLSDVE--ELVEKENQASRKGQLVQKESMDTINHAS 375
NQ ++ Q M++L+S + + V + + + Q ++ D + A
Sbjct: 614 -----NQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQ 668
Query: 376 QLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQREL 435
+ + ++ ++ ++ Y + + L + +R TQ +
Sbjct: 669 ISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQ- 727
Query: 436 VDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDY---NAKLSDLQEALDQALNYV 492
LS AES L N + D Y N S QEA A ++V
Sbjct: 728 -----------LSLAESEASLGNTN-------IPASDHYVGPNGFKSLAQEATRLAESHV 769
Query: 493 RDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRL------TLSELDD 546
A +M + T + ++ VR+ + S S S D L T S
Sbjct: 770 ESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQ 829
Query: 547 IIKNASGIYAEIDGAKS-----ELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRKL 601
+ + A+ AEI+ +S L +S L +S Q ++ A+ ++Q+A+ LS +
Sbjct: 830 LTREAT--QAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQ--VEEAKRIKQKADSLSSLV 885
Query: 602 -HSSDMNGLVQKAL-----DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQI 655
D QK L +A + +N + ++++ A R +A+S +
Sbjct: 886 TRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALS-MGNAT 944
Query: 656 IYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAA 715
Y E E++L RE + ++ EA A+ R S + ++SDA + Q A
Sbjct: 945 FY---EVESILKNLREFDLQVDNRKAEAEE--------AMKRLSYISQKVSDASDKTQQA 993
Query: 716 ER--GDAQQRLGQSRLITEEANRTTMEVQQ 743
ER G A +++ EA + E++Q
Sbjct: 994 ERALGSAAADAQRAKNGAGEALEISSEIEQ 1023
Score = 31.2 bits (69), Expect = 9.6
Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 7/65 (10%)
Query: 65 EKCNAGFFHTLSGE---CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
++C +G+++ G C C C G+S C + Y VH +T + +DG+
Sbjct: 167 DRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQD----VDGWKAVQ 222
Query: 122 IRGAP 126
G+P
Sbjct: 223 RNGSP 227
>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
Length = 1111
Score = 129 bits (325), Expect = 2e-29
Identities = 150/645 (23%), Positives = 259/645 (40%), Gaps = 98/645 (15%)
Query: 77 GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136
G C+PC+C G C +G C N E C C G+ D P+ C+PCPC
Sbjct: 411 GTCIPCNCQGGG-ACDPDTGDCYSGDENPDIE-CADCPIGFYNDP--HDPRSCKPCPCH- 465
Query: 137 PHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLIGST---CKKCDCSGN 192
F+ S + V C C G CE CA GY+G+P C+ C C+ N
Sbjct: 466 ---NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN 522
Query: 193 SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGD---ARIAKNCAVCNC---GGG 246
DP+ +CD +TG+C C+ NT G C++C GY+GD A C CNC G
Sbjct: 523 VDPSAS-GNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581
Query: 247 P--CDSVTGECL-EEGFEPPT------GCDKCVWD--------LTDALRLAAL-SIEEGK 288
P C S G C+ + GF P C C + R+ AL S +G
Sbjct: 582 PVGCRS-DGTCVCKPGFGGPNCEHGAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGG 640
Query: 289 SGVLSVSSGAAAHRHVNEINATIYLLKTKLSE-RENQYALRKIQINNAENTMKSLLSDVE 347
GV+ + + + I L ++SE L+ ++ + EN+ +S L D++
Sbjct: 641 DGVVPDTELEGRMQQAEQALQDI-LRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLK 699
Query: 348 ELVEK---------------------------ENQAS----------------------R 358
VE+ E++AS +
Sbjct: 700 MTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQ 759
Query: 359 KGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQK 418
+ + + +++ ++ QL + D + + K L+ G + + L +K
Sbjct: 760 EATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEK 819
Query: 419 MLEEIRSRQPFFTQRELVDEEADEAYE-LLSQAESWQRLHNETRTLFPVVLEQLDDYNAK 477
+ + Q + + EAD +Y+ L +S RL + F V E+ K
Sbjct: 820 LEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQV--EEAKRIKQK 877
Query: 478 LSDLQEALDQALN-YVRDAEDM-NRATAARQ--RDHEKQQERVREQMEVVNMSLSTSADS 533
L + + ++ + R +++ N A+Q ++ + +E+ + + N++ S + ++
Sbjct: 878 ADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEA 937
Query: 534 LTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQE 593
L+ T E++ I+KN ++D K+E + + LS +S V +A D Q ++
Sbjct: 938 LSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQK-VSDASDKTQQAERA 996
Query: 594 ANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFAL 638
+ + NG + +S + + I + EAN TA+ AL
Sbjct: 997 LGSAAADAQRA-KNGAGEALEISSEIEQEIGSLNLEANVTADGAL 1040
Score = 95.9 bits (237), Expect = 3e-19
Identities = 62/182 (34%), Positives = 82/182 (45%), Gaps = 36/182 (19%)
Query: 82 CDCNGNSNECL--------DGSGY-CVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPC 132
CDCNG S +C+ G+G+ C++C NT G HCEKC +G+ R C PC
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR---CLPC 84
Query: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC-------- 184
C + R + + RC C G C+RC PG++ +L + C
Sbjct: 85 NC-----NSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFH---MLTDAGCTQDQRLLD 136
Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNC 243
KCDC DP I CD G+C C TG +C+RC GYY D + C C C
Sbjct: 137 SKCDC----DPAGIAGPCD--AGRC-VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Query: 244 GG 245
G
Sbjct: 190 YG 191
Score = 73.9 bits (180), Expect = 1e-12
Identities = 49/140 (35%), Positives = 63/140 (45%), Gaps = 23/140 (16%)
Query: 65 EKCNAGFF-HTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
EKC GF+ H C+PC+CN G+ + D SG C C+ TG C++CL G+ +
Sbjct: 66 EKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRC-SCKPGVTGARCDRCLPGFHMLT 124
Query: 122 IRGAPQ----FCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY--- 174
G Q C C A A C A RC+C G C+RC GYY
Sbjct: 125 DAGCTQDQRLLDSKCDC---DPAGIAGPC----DAGRCVCKPAVTGERCDRCRSGYYNLD 177
Query: 175 -GNPLLIGSTCKKCDCSGNS 193
GNP C +C C G+S
Sbjct: 178 GGNP----EGCTQCFCYGHS 193
Score = 71.2 bits (173), Expect = 8e-12
Identities = 147/690 (21%), Positives = 246/690 (35%), Gaps = 147/690 (21%)
Query: 154 RCICNENYAGPNCERCAPGYYGNPLLIG--STCKKCDC--------------SGNSDPNL 197
+CIC Y G C+ CA GY + +G TC C+C SG+ +P++
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDI 440
Query: 198 IFEDC-------------------------------DEVTGQCRNCLRNTTGFKCERCAP 226
DC +EV C NC TG +CE CA
Sbjct: 441 ECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVV--CNNCPPGVTGARCELCAD 498
Query: 227 GYYGDA----RIAKNCAVCNC-------GGGPCDSVTGECL--------------EEGF- 260
GY+GD + C C C G CD +TG CL + G+
Sbjct: 499 GYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
Query: 261 -EP--PTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTK 317
+P P DKC + + + + V G H Y
Sbjct: 559 GDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAFSCPACY----- 613
Query: 318 LSERENQYALRKIQINNAENTMKSLLSDVE--ELVEKENQASRKGQLVQKESMDTINHAS 375
NQ ++ Q M++L+S + + V + + + Q ++ D + A
Sbjct: 614 -----NQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQ 668
Query: 376 QLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQREL 435
+ + ++ ++ ++ Y + + L + +R TQ +
Sbjct: 669 ISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQ- 727
Query: 436 VDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDY---NAKLSDLQEALDQALNYV 492
LS AES L N + D Y N S QEA A ++V
Sbjct: 728 -----------LSLAESEASLGNTN-------IPASDHYVGPNGFKSLAQEATRLAESHV 769
Query: 493 RDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRL------TLSELDD 546
A +M + T + ++ VR+ + S S S D L T S
Sbjct: 770 ESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQ 829
Query: 547 IIKNASGIYAEIDGAKS-----ELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRKL 601
+ + A+ AEI+ +S L +S L +S Q ++ A+ ++Q+A+ LS +
Sbjct: 830 LTREAT--QAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQ--VEEAKRIKQKADSLSSLV 885
Query: 602 -HSSDMNGLVQKAL-----DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQI 655
D QK L +A + +N + ++++ A R +A+S +
Sbjct: 886 TRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALS-MGNAT 944
Query: 656 IYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAA 715
Y E E++L RE + ++ EA A+ R S + ++SDA + Q A
Sbjct: 945 FY---EVESILKNLREFDLQVDNRKAEAEE--------AMKRLSYISQKVSDASDKTQQA 993
Query: 716 ER--GDAQQRLGQSRLITEEANRTTMEVQQ 743
ER G A +++ EA + E++Q
Sbjct: 994 ERALGSAAADAQRAKNGAGEALEISSEIEQ 1023
Score = 31.2 bits (69), Expect = 9.6
Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 7/65 (10%)
Query: 65 EKCNAGFFHTLSGE---CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDS 121
++C +G+++ G C C C G+S C + Y VH +T + +DG+
Sbjct: 167 DRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQD----VDGWKAVQ 222
Query: 122 IRGAP 126
G+P
Sbjct: 223 RNGSP 227
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 128 bits (321), Expect = 6e-29
Identities = 82/264 (31%), Positives = 117/264 (44%), Gaps = 30/264 (11%)
Query: 15 LLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHT 74
L+ ++ + A + D+ G+ E + G P+ + C+ G+ T
Sbjct: 1088 LIRASYAQQPAESRVSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRT 1147
Query: 75 LSG----ECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQ 130
SG C C C+G+S C +G C CQ +T G CE+C GY GD+ RG PQ CQ
Sbjct: 1148 PSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQ 1207
Query: 131 PCPC-PLPHLANFAESCY-RKNGAVRC-ICNENYAGPNCERCAPGYYGNPLLIGSTCKK- 186
CPC P A +C+ +G C C+ ++G +CERCAPGYYGNP G C++
Sbjct: 1208 LCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQ-GQPCQRD 1266
Query: 187 --------CDCSGNSDP-NLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAK 236
C+C DP + CD GQC+ C G C C P ++ A
Sbjct: 1267 SQVPGPIGCNC----DPQGSVSSQCD-AAGQCQ-CKAQVEGLTCSHCRPHHFHLSASNPD 1320
Query: 237 NCAVCNCGGGPCDSVTGECLEEGF 260
C C C G +T +C +
Sbjct: 1321 GCLPCFCMG-----ITQQCASSAY 1339
Score = 125 bits (314), Expect = 4e-28
Identities = 74/230 (32%), Positives = 105/230 (45%), Gaps = 23/230 (10%)
Query: 29 DNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSGE----CVPCDC 84
D A + +++ GR E E R +G + E C+A F G C C+C
Sbjct: 709 DIAMDTTVTHATSHGRAHSVE--ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNC 766
Query: 85 NGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP-LPHLANFA 143
NG+++ C G+C++CQ NT G C KC G+ GD+++ C+PCPCP + F+
Sbjct: 767 NGHASSCDPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFS 826
Query: 144 ESCY-RKNGAVRC-ICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFED 201
++C+ +G C C Y G CE CAPGY GNP+ G C+ N
Sbjct: 827 DTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPV--------NQEIVR 878
Query: 202 CDE-----VTGQCRNCLRNTTGFKCERCAPG-YYGDARIAKNCAVCNCGG 245
CDE +G+ C N G C CA G ++ R C C C G
Sbjct: 879 CDERGSMGTSGEACRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCMG 928
Score = 117 bits (292), Expect = 1e-25
Identities = 59/143 (41%), Positives = 74/143 (51%), Gaps = 7/143 (4%)
Query: 49 ETSEPRVALGRLPPAAEKCNAGFFHTLSG----ECVPCDCNGNSNECLDGSGYCVHCQRN 104
E E R G + + + C G+ T SG C C+CNG+S+ C +G C CQ N
Sbjct: 1526 EVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHN 1585
Query: 105 TTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLAN-FAESCYRKN-GAVRC-ICNENY 161
GE CE C GY GD+ G P+ CQPC CPL + N F+ +C G RC C Y
Sbjct: 1586 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGY 1645
Query: 162 AGPNCERCAPGYYGNPLLIGSTC 184
G CE+C PGY GNP + G C
Sbjct: 1646 TGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 78.2 bits (191), Expect = 7e-14
Identities = 40/93 (43%), Positives = 50/93 (53%), Gaps = 11/93 (11%)
Query: 155 CICNENYAGPNCERCAPGYY--GNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNC 212
C C Y G +C+ CAPGY G+ L +G C+ C+C+G+SD C TG C C
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGH-CELCECNGHSDL------CHPETGACSQC 1582
Query: 213 LRNTTGFKCERCAPGYYGDARIA--KNCAVCNC 243
N G CE CAPGYYGDA ++C C C
Sbjct: 1583 QHNAAGEFCELCAPGYYGDATAGTPEDCQPCAC 1615
Score = 70.1 bits (170), Expect = 2e-11
Identities = 41/138 (29%), Positives = 57/138 (41%), Gaps = 10/138 (7%)
Query: 101 CQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNEN 160
C G C+ C GY C+ C C ++ C+ + GA C N
Sbjct: 1532 CPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECN-----GHSDLCHPETGACSQ-CQHN 1585
Query: 161 YAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDCDEVTG---QCRNCLRNT 216
AG CE CAPGYYG+ C+ C C + N+ C+ + +C C
Sbjct: 1586 AAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGY 1645
Query: 217 TGFKCERCAPGYYGDARI 234
TG CE+C PGY G+ +
Sbjct: 1646 TGQYCEQCGPGYVGNPSV 1663
Score = 66.2 bits (160), Expect = 3e-10
Identities = 36/135 (26%), Positives = 68/135 (50%), Gaps = 7/135 (5%)
Query: 1490 IRLRTRSSHGMIFYVSDQ-----EENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDG 1544
+ +RT ++ G++ + + + DF++L L G LV+ + +G + ++ S++ NDG
Sbjct: 4232 LEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEARLVSEDPINDG 4291
Query: 1545 LWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSI 1604
WH V +RE G + +DG ++ P KG +Y+GG + + +S
Sbjct: 4292 EWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSS- 4350
Query: 1605 YSFSGCLSNLQLNGA 1619
+GC+ NL L+ A
Sbjct: 4351 -GITGCVKNLVLHSA 4364
Score = 54.3 bits (129), Expect = 1e-06
Identities = 39/149 (26%), Positives = 60/149 (40%), Gaps = 10/149 (6%)
Query: 1511 DFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEE 1570
DF++L + G L + + +G +RS E G WH V R G L ++G R +
Sbjct: 3978 DFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGRWHRVSAERLNKDGSLRVNGGRPVLR 4037
Query: 1571 SLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASI--------- 1621
S P + +YLGGV P + + N F GC+ + +NG +
Sbjct: 4038 SSPGKSQGLNLHTLLYLGGVEPSVPL-SPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGS 4096
Query: 1622 TSASQTFSVTPCFEGPMETGTYFSTEGGY 1650
Q + +PC P + G G Y
Sbjct: 4097 QGIGQCYDSSPCERQPCQHGATCMPAGEY 4125
Score = 53.5 bits (127), Expect = 2e-06
Identities = 40/169 (23%), Positives = 79/169 (46%), Gaps = 16/169 (9%)
Query: 1635 EGPMETGTYFSTEGGYVVLDESFNIGLKF---EIAFEVRPRSSSGTLVH-----GHSVNG 1686
+ P + G YF +G F+ L I EVR ++SG L+ G + G
Sbjct: 4197 DAPGQYGAYFHDDGFLAFPGHVFSRSLPEVPETIELEVRTSTASGLLLWQGVEVGEAGQG 4256
Query: 1687 -EYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVN 1745
+++++ +++G ++ + G + + + + DG WHR+T +R+ + VD E
Sbjct: 4257 KDFISLGLQDGHLVFRYQLGSGE--ARLVSEDPINDGEWHRVTALREGRRGSIQVDGE-- 4312
Query: 1746 HVVGPLNPKP---IDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVI 1791
+V +P P ++ + V++GG P+ S TGC+++ V+
Sbjct: 4313 ELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNLVL 4361
Score = 44.7 bits (104), Expect = 8e-04
Identities = 35/148 (23%), Positives = 59/148 (39%), Gaps = 13/148 (8%)
Query: 1485 KSQFSIRLRTRSSHGMIFYVSDQE-----------ENDFMTLFLAHGRLVYMFNVGHKKL 1533
K + I R S+ GM+ Y + + DF++ L GR + F+ G
Sbjct: 3685 KFEIKITFRPDSADGMLLYNGQKRVPGSPTNLANRQPDFISFGLVGGRPEFRFDAGSGMA 3744
Query: 1534 KIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPG 1593
IR G +H V +R + G L++ L + + + +YLGG
Sbjct: 3745 TIRHPTPLALGHFHTVTLLRSLTQGSLIVGDLAPVNGTSQGKFQGLDLNEELYLGGYPDY 3804
Query: 1594 KAVKNVQINSIYSFSGCLSNLQLNGASI 1621
A+ ++S F GC+ L++ G I
Sbjct: 3805 GAIPKAGLSS--GFIGCVRELRIQGEEI 3830
Score = 43.1 bits (100), Expect = 0.002
Identities = 42/174 (24%), Positives = 70/174 (40%), Gaps = 33/174 (18%)
Query: 1662 KFEIAFEVRPRSSSGTLVH-------GHSVN-----GEYLNVHMKNGQVIVKVNNGIRDF 1709
KFEI RP S+ G L++ G N ++++ + G+ + + G
Sbjct: 3685 KFEIKITFRPDSADGMLLYNGQKRVPGSPTNLANRQPDFISFGLVGGRPEFRFDAG--SG 3742
Query: 1710 STSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNP---------KPIDHRE 1760
++ L G +H +T++R L +VG L P + +D E
Sbjct: 3743 MATIRHPTPLALGHFHTVTLLRSLTQGSL--------IVGDLAPVNGTSQGKFQGLDLNE 3794
Query: 1761 PVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSCP 1814
+++GG P+ P+ S F GC+R I G + F L A I+ CP
Sbjct: 3795 ELYLGGYPDYGAIPKAGLSSGFIGCVRELRIQGEEIVFHDLNLT--AHGISHCP 3846
Score = 41.6 bits (96), Expect = 0.007
Identities = 44/190 (23%), Positives = 77/190 (40%), Gaps = 17/190 (8%)
Query: 1633 CFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNG---EYL 1689
C EG T S G Y+ L N + + E +P + G L+ +G +++
Sbjct: 3921 CEEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLAPDGVLLFSGGKSGPVEDFV 3980
Query: 1690 NVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVG 1749
++ M G + + G + + L GRWHR++ R + D VN
Sbjct: 3981 SLAMVGGHLEFRYELG--SGLAVLRSAEPLALGRWHRVSAER----LNKDGSLRVNGGRP 4034
Query: 1750 PLNPKP-----IDHREPVFVGGVPESL-LTPRLAPSKPFTGCIRHFVIDGHPVSFSKAAL 1803
L P ++ +++GGV S+ L+P S F GC+ ++G + + + L
Sbjct: 4035 VLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFL 4094
Query: 1804 VSGAVSINSC 1813
G+ I C
Sbjct: 4095 --GSQGIGQC 4102
Score = 35.0 bits (79), Expect = 0.67
Identities = 31/89 (34%), Positives = 38/89 (42%), Gaps = 21/89 (23%)
Query: 208 QCRNCLRNTTGFKCERC------APG--YYGDARIAKNCAVCNCGG--GPCDSVTGECL- 256
+CR C +G CE C PG Y G C+ CNC G CD V G CL
Sbjct: 730 ECR-CPIGYSGLSCESCDAHFTRVPGGPYLG------TCSGCNCNGHASSCDPVYGHCLN 782
Query: 257 -EEGFEPPTGCDKC-VWDLTDALRLAALS 283
+ E P C+KC DA++ A S
Sbjct: 783 CQHNTEGPQ-CNKCKAGFFGDAMKATATS 810
Score = 31.6 bits (70), Expect = 7.4
Identities = 41/188 (21%), Positives = 70/188 (37%), Gaps = 21/188 (11%)
Query: 834 QSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIK 893
+ V ++T L T Y K +K ++AD +LY G K LA +
Sbjct: 3660 ERVVPYFTQTPYSFLPLPTIKDAYRKFEIKITFRPDSADGMLLYNGQKRVPGSPTNLANR 3719
Query: 894 NDNLVYVYNLGTKDVEIPLDS--------KPVSSWPAYFSIVKIERVGKHGKVFLTVPSL 945
+ + +G + E D+ P +F V + R G + +
Sbjct: 3720 QPDFISFGLVGGRP-EFRFDAGSGMATIRHPTPLALGHFHTVTLLRSLTQGSLIV----- 3773
Query: 946 SSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLN 1005
A +G+F G LDL+ E Y+GG P +P + GF+GC+ +
Sbjct: 3774 GDLAPVNGTSQGKFQG----LDLNEE---LYLGGYPDYGAIPKAGLSSGFIGCVRELRIQ 3826
Query: 1006 NDVISLYN 1013
+ I ++
Sbjct: 3827 GEEIVFHD 3834
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 106 bits (265), Expect = 2e-22
Identities = 85/357 (23%), Positives = 168/357 (47%), Gaps = 40/357 (11%)
Query: 1483 GAKSQFSIRLRTRSSHGMI-FYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQ--- 1538
G K+ F RT+ G+I F S + ++ L L GRL ++F+ +++ +
Sbjct: 1543 GIKASF----RTKVPEGLIVFAASPGNQEEYFALQLKKGRLYFLFDPQGSPVEVTTTNDH 1598
Query: 1539 -EKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVK 1597
++Y+DG WH++I IR ++ G++ +DG+ ++ ++LGG+ +
Sbjct: 1599 GKQYSDGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVIGDNTGVFLGGLPRSYTIL 1658
Query: 1598 NVQINSIY-SFSGCLSNLQL----NGASI------TSASQTFSVTPCFEG---PMETGTY 1643
I F GCL ++ N ++I S+ + +V +EG + G
Sbjct: 1659 RKDPEIIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQINVYNSWEGCPASLNEGAQ 1718
Query: 1644 FSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNG-EYLNVHMKNGQVIVKV 1702
F G + F+ G+ FEI+F+ R +G L+ ++ +G ++L + +K+G + ++
Sbjct: 1719 FLGAGFLELHPYMFHGGMNFEISFKFRTDQLNGLLLFVYNKDGPDFLAMELKSGILTFRL 1778
Query: 1703 NNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPV 1762
N + + S C+G+W+++ + ++ + + V+ + H +P+ PV
Sbjct: 1779 NTSLAFTQVDLLLGLSYCNGKWNKVIIKKEGSFISASVNGLMKH-ASESGDQPLVVNSPV 1837
Query: 1763 FVGGVPESLLT--PRLAPSKPFTGCIRHFVIDGHPVSFSKAALV------SGAVSIN 1811
+VGG+P+ LL L + F GC++ V F++ A+V SGAV +N
Sbjct: 1838 YVGGIPQELLNSYQHLCLEQGFGGCMK-------DVKFTRGAVVNLASVSSGAVRVN 1887
Score = 92.4 bits (228), Expect = 4e-18
Identities = 61/219 (27%), Positives = 88/219 (40%), Gaps = 38/219 (17%)
Query: 79 CVPCDCNGNSNEC--------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGD--SI 122
C PC CN +S C G G C C+ NTTG +CE C D + +
Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631
Query: 123 RGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGS 182
A C+PC C N + C + G +C C + +G C +C G+Y L
Sbjct: 632 PSAIDVCKPCDCDTVGTRNGSILCDQIGG--QCNCKRHVSGRQCNQCQNGFYNLQELDPD 689
Query: 183 TCKKCDC--SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGY-----YGDARIA 235
C C+C SG D ++ C + +GQC+ C N G +C+ C G+ + D
Sbjct: 690 GCSPCNCNTSGTVDGDI---TCHQNSGQCK-CKANVIGLRCDHCNFGFKFLRSFNDV--- 742
Query: 236 KNCAVCNCG-----GGPCDSVTGECLEEGFEPPTGCDKC 269
C C C C+ +G+C + CD C
Sbjct: 743 -GCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTC 780
Score = 87.8 bits (216), Expect = 9e-17
Identities = 66/230 (28%), Positives = 98/230 (42%), Gaps = 47/230 (20%)
Query: 74 TLSGECVPCDCNGNSNEC-LDGSGYCVHCQRN--TTGEHCEKCLDGYIGDSIRGAPQF-- 128
T+SG C C+G+++ C Y C + T G HC++CL Y R Q
Sbjct: 513 TISGRC---QCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569
Query: 129 --CQPCPCPLPHLANFAESC-------------YRKNGAVRCICNENYAGPNCERCAPGY 173
C+PC C + ++SC +R G V C N G NCE C +
Sbjct: 570 FNCKPCQC-----NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYF 624
Query: 174 Y----GNPLLIGSTCKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG 227
+ +P I CK CDC G + +++ CD++ GQC NC R+ +G +C +C G
Sbjct: 625 FRQVGADPSAI-DVCKPCDCDTVGTRNGSIL---CDQIGGQC-NCKRHVSGRQCNQCQNG 679
Query: 228 YYGDARI-AKNCAVCNC-------GGGPCDSVTGECLEEGFEPPTGCDKC 269
+Y + C+ CNC G C +G+C + CD C
Sbjct: 680 FYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHC 729
Score = 87.0 bits (214), Expect = 1e-16
Identities = 65/224 (29%), Positives = 95/224 (42%), Gaps = 35/224 (15%)
Query: 65 EKCNAGFFHTLSGE---CVPCDCN--GNSNE-CLDGSGYCVHCQRNTTGEHCEKCLDGYI 118
+ CN GF S C PC CN G+ N+ C SG C C++ G C+ C + +
Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAKGLQCDTCRENFY 785
Query: 119 GDSIRGAPQFCQPCPC----PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
G + C+ C C LP C K G +CIC N G C +C G +
Sbjct: 786 GLDVTN----CKACDCDTAGSLP-----GTVCNAKTG--QCICKPNVEGRQCNKCLEGNF 834
Query: 175 GNPLLIGSTCKKCDC--SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-D 231
C C+C +G + +L+ C++ TGQC C TG +C +C P Y
Sbjct: 835 YLRQNNSFLCLPCNCDKTGTINGSLL---CNKSTGQC-PCKLGVTGLRCNQCEPHRYNLT 890
Query: 232 ARIAKNCAVCNCG------GGPCDSVTGECLEEGFEPPTGCDKC 269
++C +C C G CD ++G+CL C++C
Sbjct: 891 IDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQC 934
Score = 87.0 bits (214), Expect = 1e-16
Identities = 66/222 (29%), Positives = 91/222 (40%), Gaps = 30/222 (13%)
Query: 66 KCNAGFFHTLSGE---CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117
KC G F+ C+PC+C+ S C +G C C+ TG C +C
Sbjct: 828 KCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCP-CKLGVTGLRCNQCEPHR 886
Query: 118 IGDSIRGAPQFCQPCPCP----LPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGY 173
+I Q CQ C C LP C +G +C+C N G C +C PG+
Sbjct: 887 YNLTIDNF-QHCQMCECDSLGTLP-----GTICDPISG--QCLCVPNRQGRRCNQCQPGF 938
Query: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR 233
Y +P + C C C N I C+ +TGQC + G +C++C Y+G
Sbjct: 939 YISPGN-ATGCLPCSCHTTGAVNHI---CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDP 994
Query: 234 IAKNCAVCNCG-----GGPCDSVTGECLEEGFEPPTGCDKCV 270
C CNC C VTG+C + F + CD CV
Sbjct: 995 QTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036
Score = 66.6 bits (161), Expect = 2e-10
Identities = 48/153 (31%), Positives = 65/153 (42%), Gaps = 17/153 (11%)
Query: 79 CVPCDCNG----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPC 134
C C+C+ C SG C+ C N G C +C G+ G C PC C
Sbjct: 897 CQMCECDSLGTLPGTICDPISGQCL-CVPNRQGRRCNQCQPGFYISP--GNATGCLPCSC 953
Query: 135 PLPHLANFAESCYRKNGAVRCICNE-NYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNS 193
N C G +C+C + + AG C++C Y+G G C+ C+C +
Sbjct: 954 HTTGAVNHI--CNSLTG--QCVCQDASIAGQRCDQCKDHYFGFDPQTGR-CQPCNCHLSG 1008
Query: 194 DPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226
N E C VTGQC C + TG KC+ C P
Sbjct: 1009 ALN---ETCHLVTGQCF-CKQFVTGSKCDACVP 1037
Score = 59.7 bits (143), Expect = 3e-08
Identities = 35/112 (31%), Positives = 52/112 (46%), Gaps = 13/112 (11%)
Query: 66 KCNAGFFHTLSGE--CVPCDCNGN---SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG- 119
+C GF+ + C+PC C+ ++ C +G CV + G+ C++C D Y G
Sbjct: 933 QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992
Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAP 171
D G CQPC C L N E+C+ G +C C + G C+ C P
Sbjct: 993 DPQTGR---CQPCNCHLSGALN--ETCHLVTG--QCFCKQFVTGSKCDACVP 1037
Score = 56.2 bits (134), Expect = 3e-07
Identities = 74/269 (27%), Positives = 103/269 (38%), Gaps = 49/269 (18%)
Query: 1045 FDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMV---NGSMFFRLEMRNGYLH 1101
F G+GY T T RT GLI+ N +F L+++ G L+
Sbjct: 1522 FIGNGYCKFPSSTHPVNT-DFTGIKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLY 1580
Query: 1102 VFYDFGFSGGPVHLEDTLKKA-QINDAKYHEISIIYHNDKKMILVVDRRHVKS---MDNE 1157
+D G PV + T Q +D K+HEI I H I +D + S ++
Sbjct: 1581 FLFDP--QGSPVEVTTTNDHGKQYSDGKWHEIIAIRHQAFGQI-TLDGIYTGSSAILNGS 1637
Query: 1158 KMKIPFTDIYIGGAP---------PEILQSRALRAHLPLDINFRGCMKGFQFQKK----- 1203
+ T +++GG P PEI+Q F GC+K F K
Sbjct: 1638 TVIGDNTGVFLGGLPRSYTILRKDPEIIQK-----------GFVGCLKDVHFMKNYNPSA 1686
Query: 1204 -----DFNLLE-QTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDG--FEGGFN 1255
D+ E Q GCP ++ A F G F+ + F G FE F
Sbjct: 1687 IWEPLDWQSSEEQINVYNSWEGCPAS--LNEGAQFLGAGFL-ELHPYMFHGGMNFEISFK 1743
Query: 1256 FRTLQPNGLLF--YYASGSDVFSISLDNG 1282
FRT Q NGLL Y G D ++ L +G
Sbjct: 1744 FRTDQLNGLLLFVYNKDGPDFLAMELKSG 1772
Score = 51.6 bits (122), Expect = 7e-06
Identities = 70/356 (19%), Positives = 144/356 (40%), Gaps = 44/356 (12%)
Query: 862 VKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWP 921
+K T+ + I++ S ++EY L +K L ++++
Sbjct: 1544 IKASFRTKVPEGLIVFAASPGNQEEYFALQLKKGRLYFLFD------------------- 1584
Query: 922 AYFSIVKIERVGKHGKVFL-----TVPSLSSTAEEKFIKKGEFSGDDSLLD---LDPEDT 973
S V++ HGK + + ++ A + G ++G ++L+ + ++T
Sbjct: 1585 PQGSPVEVTTTNDHGKQYSDGKWHEIIAIRHQAFGQITLDGIYTGSSAILNGSTVIGDNT 1644
Query: 974 VFYVGGVPSNFKL---PTSLNLPGFVGCLELATL--NNDVISLYNFKHIYNMDPSTSVPC 1028
++GG+P ++ + + GFVGCL+ N + +++ + + +V
Sbjct: 1645 GVFLGGLPRSYTILRKDPEIIQKGFVGCLKDVHFMKNYNPSAIWEPLDWQSSEEQINVYN 1704
Query: 1029 ARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVN-- 1086
+ + + + A + G+G+ + G G + RT NGL+L + N
Sbjct: 1705 SWEGCPASLNEGAQFL--GAGFLELHPYMFHG--GMNFEISFKFRTDQLNGLLLFVYNKD 1760
Query: 1087 GSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVV 1146
G F +E+++G L + + V D L + K++++ I V
Sbjct: 1761 GPDFLAMELKSGILTFRLNTSLAFTQV---DLLLGLSYCNGKWNKVIIKKEGSFISASVN 1817
Query: 1147 DRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQK 1202
S ++ + + +Y+GG P E+L S HL L+ F GCMK +F +
Sbjct: 1818 GLMKHASESGDQPLVVNSPVYVGGIPQELLNS---YQHLCLEQGFGGCMKDVKFTR 1870
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 102 bits (255), Expect = 3e-21
Identities = 73/249 (29%), Positives = 100/249 (40%), Gaps = 47/249 (18%)
Query: 82 CDCNGNSNECLD----------GSGYCVH----CQRNTTGEHCEKCLDGY------IGDS 121
C CNG++++C+ G+ + VH C+ NT G HC+ C Y D
Sbjct: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADG 321
Query: 122 IRGAPQFCQPCPC----PLPHL-ANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGN 176
GAP C+ C C H N E+ ++G V C N G C+RC PG+Y +
Sbjct: 322 KTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRD 381
Query: 177 ---PLLIGSTCKKCDCSGNSD---PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG 230
P CK C C P CD G C C G +C+RC GY+G
Sbjct: 382 LRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC-PCKPGVAGRRCDRCMVGYWG 440
Query: 231 DARIAKNCAVCNCGGGPCDSVTGECLEE-----------GFEPPTGCDKCVWDLTDALRL 279
C C+C G CD +TG+C+ F P + W+ DA
Sbjct: 441 FGDY--GCRPCDCAGS-CDPITGDCISSHTDIDWYHEVPDFRPVHNKSEPAWEWEDAQGF 497
Query: 280 AALSIEEGK 288
+AL + GK
Sbjct: 498 SAL-LHSGK 505
Score = 86.7 bits (213), Expect = 2e-16
Identities = 52/151 (34%), Positives = 67/151 (44%), Gaps = 35/151 (23%)
Query: 78 ECVPCDCNGNSNECL-----------DGSGYCVHCQRNTTGEHCEKCLDGYIGDSIR--G 124
EC C CNG+++ C G C CQ NT G++C++C G+ D R
Sbjct: 328 ECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFS 387
Query: 125 APQFCQPCPC------PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
AP C+PC C LP AN C NG C C AG C+RC GY+G
Sbjct: 388 APDACKPCSCHPVGSAVLP--ANSVTFCDPSNG--DCPCKPGVAGRRCDRCMVGYWG--- 440
Query: 179 LIGSTCKKCDCSGNSDPNLIFEDCDEVTGQC 209
C+ CDC+G+ CD +TG C
Sbjct: 441 FGDYGCRPCDCAGS---------CDPITGDC 462
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 99.8 bits (247), Expect = 2e-20
Identities = 67/202 (33%), Positives = 92/202 (45%), Gaps = 26/202 (12%)
Query: 78 ECVPCDCNGNSNEC---------LDGS--GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
EC CDCNG+S C G+ G C +C+ +T G++CE+C Y + GA
Sbjct: 312 ECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGAS 371
Query: 127 --QFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
+ C C C P A C G +C+C E+ G C+ C PG+ G C
Sbjct: 372 IQETCISCECD-PDGAVPGAPCDPVTG--QCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244
+CDC N + CDE +G+C CL N G KC++CAP Y+ + C C C
Sbjct: 429 HRCDC--NILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACD 484
Query: 245 -----GGPCDSVTGEC-LEEGF 260
C+ TG+C EGF
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGF 506
Score = 93.2 bits (230), Expect = 2e-18
Identities = 175/784 (22%), Positives = 297/784 (37%), Gaps = 134/784 (17%)
Query: 79 CVPCDCN--GNSNE--CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPC 134
C CDCN G+ + C + SG C+ C N G C++C Y G Q C+PC C
Sbjct: 428 CHRCDCNILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASG--QGCEPCAC 483
Query: 135 PLPHLANFAESCYRKNGAVRCICNENYAGPNCE-----RCAPGYYGNPLLIGSTCKKCDC 189
PH + + C + G +C C E + G C +C YG+ + + C+ CDC
Sbjct: 484 D-PH-NSLSPQCNQFTG--QCPCREGFGGLMCSAAAIRQCPDRTYGD---VATGCRACDC 536
Query: 190 S--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGP 247
G P CD+ +G+C C TG +C++C GY + C C+ P
Sbjct: 537 DFRGTEGPG-----CDKASGRCL-CRPGLTGPRCDQCQRGYCNRYPV---CVACH----P 583
Query: 248 CDSVTGECLEE---GFEPPTGCDKCVWD---LTDALRLAALSIEEGKSGVLSV----SSG 297
C L E F +W L D R A I + KS + + SS
Sbjct: 584 CFQTYDADLREQALRFGRLRNATASLWSGPGLED--RGLASRILDAKSKIEQIRAVLSSP 641
Query: 298 AAAHRHVNEINATIYLLKTKLS--------ERENQYALRKIQ-INNAENTMKSLLSDVEE 348
A + V ++ + I L+ L E E R ++ ++ + N + ++ E
Sbjct: 642 AVTEQEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKRE 701
Query: 349 LVEKENQASRKGQL--------VQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGE 400
EK + A G ++ ++ +S+L++Q D R + + + + G
Sbjct: 702 QFEKISSADPSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGG 761
Query: 401 EHELSPKEISEKLVLAQKMLEEIRSRQPFFTQ-----RELVDEEADEAYELLSQAESWQR 455
S KLV + + + P F + R++ EL Q ++
Sbjct: 762 TG-------SPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQ-DNGTA 813
Query: 456 LHNETRTLFP----------VVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAAR 505
+ R + P V EQL +NA+L ++ +R AE+ +
Sbjct: 814 CGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQ-------MIRAAEESASQIQSS 866
Query: 506 QRDHEKQQERVREQMEV----VNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGA 561
+ E Q R QME + + D LT P + + ++ + ++ D A
Sbjct: 867 AQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSA 926
Query: 562 -----KSELQVKLSNLSNLSHDLVQ--EAIDHAQDLQQEANELSRKLHSSDMNGLVQKAL 614
+E+Q + L N+ L Q + I A+ LQ EA E + H+ + G V+ +
Sbjct: 927 TVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHA--VEGQVEDVV 984
Query: 615 DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQA 674
N+ + V + EA +T + + I D V+ + + + ++ Q +
Sbjct: 985 --GNLRQGTV-ALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWT 1041
Query: 675 KAESSSDEAVADTSRRVGGALARKSALKTRLS-----DAVKQLQAAERGDAQQRLGQSRL 729
+ E +A + V + A + LS + +KQ A + + RLGQS +
Sbjct: 1042 RMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYA----ELKDRLGQSSM 1097
Query: 730 ITEEANR-------------TTMEVQQATAPMANNLTNWSQ--NLQHFDSSAYNTAVNSA 774
+ E+ R TME+ M L SQ L+ D + V
Sbjct: 1098 LGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQI 1157
Query: 775 RDAV 778
RD +
Sbjct: 1158 RDHI 1161
Score = 92.0 bits (227), Expect = 5e-18
Identities = 50/135 (37%), Positives = 63/135 (46%), Gaps = 20/135 (14%)
Query: 155 CICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNLIFEDCDE 204
C+C N AGPNCERCAP Y P C++CDC+G+S DP +
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 205 VTGQCRNCLRNTTGFKCERCAPGYYGDAR----IAKNCAVCNCG------GGPCDSVTGE 254
G C NC +T G CERC Y+ + R I + C C C G PCD VTG+
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398
Query: 255 CLEEGFEPPTGCDKC 269
C+ + CD C
Sbjct: 399 CVCKEHVQGERCDLC 413
Score = 84.3 bits (207), Expect = 1e-15
Identities = 67/225 (29%), Positives = 90/225 (40%), Gaps = 46/225 (20%)
Query: 82 CDCNGNSNECLDGSG-------------YCVHCQRNTTGEHCEKCLDGYIGDSIRGA--- 125
C C+G+++ C G CV CQ NT G +CE+C Y R A
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 126 -PQFCQPCPCPLPHLANFAESCY----------RKNGAVRCICNENYAGPNCERCAPGYY 174
CQ C C +E+C+ G V C ++ G NCERC Y+
Sbjct: 309 DAHECQRCDC-----NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363
Query: 175 GN---PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG- 230
N I TC C+C + D + CD VTGQC C + G +C+ C PG+ G
Sbjct: 364 RNRRPGASIQETCISCEC--DPDGAVPGAPCDPVTGQC-VCKEHVQGERCDLCKPGFTGL 420
Query: 231 DARIAKNCAVCNCG------GGPCDSVTGECLEEGFEPPTGCDKC 269
+ C C+C PCD +G CL CD+C
Sbjct: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQC 465
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 18/121 (14%)
Query: 62 PAAEKCNAGFFHTLSGE-CVPCDC---NGNSNECLDGSGYCVHCQRNTTGEHCE-----K 112
P ++C + SG+ C PC C N S +C +G C C+ G C +
Sbjct: 460 PKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCP-CREGFGGLMCSAAAIRQ 518
Query: 113 CLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172
C D GD G C+ C C C + +G RC+C GP C++C G
Sbjct: 519 CPDRTYGDVATG----CRACDCDFR--GTEGPGCDKASG--RCLCRPGLTGPRCDQCQRG 570
Query: 173 Y 173
Y
Sbjct: 571 Y 571
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 99.8 bits (247), Expect = 2e-20
Identities = 67/202 (33%), Positives = 92/202 (45%), Gaps = 26/202 (12%)
Query: 78 ECVPCDCNGNSNEC---------LDGS--GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
EC CDCNG+S C G+ G C +C+ +T G++CE+C Y + GA
Sbjct: 312 ECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGAS 371
Query: 127 --QFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
+ C C C P A C G +C+C E+ G C+ C PG+ G C
Sbjct: 372 IQETCISCECD-PDGAVPGAPCDPVTG--QCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244
+CDC N + CDE +G+C CL N G KC++CAP Y+ + C C C
Sbjct: 429 HRCDC--NILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACD 484
Query: 245 -----GGPCDSVTGEC-LEEGF 260
C+ TG+C EGF
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGF 506
Score = 93.2 bits (230), Expect = 2e-18
Identities = 175/784 (22%), Positives = 297/784 (37%), Gaps = 134/784 (17%)
Query: 79 CVPCDCN--GNSNE--CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPC 134
C CDCN G+ + C + SG C+ C N G C++C Y G Q C+PC C
Sbjct: 428 CHRCDCNILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASG--QGCEPCAC 483
Query: 135 PLPHLANFAESCYRKNGAVRCICNENYAGPNCE-----RCAPGYYGNPLLIGSTCKKCDC 189
PH + + C + G +C C E + G C +C YG+ + + C+ CDC
Sbjct: 484 D-PH-NSLSPQCNQFTG--QCPCREGFGGLMCSAAAIRQCPDRTYGD---VATGCRACDC 536
Query: 190 S--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGP 247
G P CD+ +G+C C TG +C++C GY + C C+ P
Sbjct: 537 DFRGTEGPG-----CDKASGRCL-CRPGLTGPRCDQCQRGYCNRYPV---CVACH----P 583
Query: 248 CDSVTGECLEE---GFEPPTGCDKCVWD---LTDALRLAALSIEEGKSGVLSV----SSG 297
C L E F +W L D R A I + KS + + SS
Sbjct: 584 CFQTYDADLREQALRFGRLRNATASLWSGPGLED--RGLASRILDAKSKIEQIRAVLSSP 641
Query: 298 AAAHRHVNEINATIYLLKTKLS--------ERENQYALRKIQ-INNAENTMKSLLSDVEE 348
A + V ++ + I L+ L E E R ++ ++ + N + ++ E
Sbjct: 642 AVTEQEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKRE 701
Query: 349 LVEKENQASRKGQL--------VQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGE 400
EK + A G ++ ++ +S+L++Q D R + + + + G
Sbjct: 702 QFEKISSADPSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGG 761
Query: 401 EHELSPKEISEKLVLAQKMLEEIRSRQPFFTQ-----RELVDEEADEAYELLSQAESWQR 455
S KLV + + + P F + R++ EL Q ++
Sbjct: 762 TG-------SPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQ-DNGTA 813
Query: 456 LHNETRTLFP----------VVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAAR 505
+ R + P V EQL +NA+L ++ +R AE+ +
Sbjct: 814 CGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQ-------MIRAAEESASQIQSS 866
Query: 506 QRDHEKQQERVREQMEV----VNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGA 561
+ E Q R QME + + D LT P + + ++ + ++ D A
Sbjct: 867 AQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSA 926
Query: 562 -----KSELQVKLSNLSNLSHDLVQ--EAIDHAQDLQQEANELSRKLHSSDMNGLVQKAL 614
+E+Q + L N+ L Q + I A+ LQ EA E + H+ + G V+ +
Sbjct: 927 TVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHA--VEGQVEDVV 984
Query: 615 DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQA 674
N+ + V + EA +T + + I D V+ + + + ++ Q +
Sbjct: 985 --GNLRQGTV-ALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWT 1041
Query: 675 KAESSSDEAVADTSRRVGGALARKSALKTRLS-----DAVKQLQAAERGDAQQRLGQSRL 729
+ E +A + V + A + LS + +KQ A + + RLGQS +
Sbjct: 1042 RMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYA----ELKDRLGQSSM 1097
Query: 730 ITEEANR-------------TTMEVQQATAPMANNLTNWSQ--NLQHFDSSAYNTAVNSA 774
+ E+ R TME+ M L SQ L+ D + V
Sbjct: 1098 LGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQI 1157
Query: 775 RDAV 778
RD +
Sbjct: 1158 RDHI 1161
Score = 92.0 bits (227), Expect = 5e-18
Identities = 50/135 (37%), Positives = 63/135 (46%), Gaps = 20/135 (14%)
Query: 155 CICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNLIFEDCDE 204
C+C N AGPNCERCAP Y P C++CDC+G+S DP +
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 205 VTGQCRNCLRNTTGFKCERCAPGYYGDAR----IAKNCAVCNCG------GGPCDSVTGE 254
G C NC +T G CERC Y+ + R I + C C C G PCD VTG+
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398
Query: 255 CLEEGFEPPTGCDKC 269
C+ + CD C
Sbjct: 399 CVCKEHVQGERCDLC 413
Score = 84.3 bits (207), Expect = 1e-15
Identities = 67/225 (29%), Positives = 90/225 (40%), Gaps = 46/225 (20%)
Query: 82 CDCNGNSNECLDGSG-------------YCVHCQRNTTGEHCEKCLDGYIGDSIRGA--- 125
C C+G+++ C G CV CQ NT G +CE+C Y R A
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 126 -PQFCQPCPCPLPHLANFAESCY----------RKNGAVRCICNENYAGPNCERCAPGYY 174
CQ C C +E+C+ G V C ++ G NCERC Y+
Sbjct: 309 DAHECQRCDC-----NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363
Query: 175 GN---PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG- 230
N I TC C+C + D + CD VTGQC C + G +C+ C PG+ G
Sbjct: 364 RNRRPGASIQETCISCEC--DPDGAVPGAPCDPVTGQC-VCKEHVQGERCDLCKPGFTGL 420
Query: 231 DARIAKNCAVCNCG------GGPCDSVTGECLEEGFEPPTGCDKC 269
+ C C+C PCD +G CL CD+C
Sbjct: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQC 465
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 18/121 (14%)
Query: 62 PAAEKCNAGFFHTLSGE-CVPCDC---NGNSNECLDGSGYCVHCQRNTTGEHCE-----K 112
P ++C + SG+ C PC C N S +C +G C C+ G C +
Sbjct: 460 PKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCP-CREGFGGLMCSAAAIRQ 518
Query: 113 CLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172
C D GD G C+ C C C + +G RC+C GP C++C G
Sbjct: 519 CPDRTYGDVATG----CRACDCDFR--GTEGPGCDKASG--RCLCRPGLTGPRCDQCQRG 570
Query: 173 Y 173
Y
Sbjct: 571 Y 571
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 99.8 bits (247), Expect = 2e-20
Identities = 67/202 (33%), Positives = 92/202 (45%), Gaps = 26/202 (12%)
Query: 78 ECVPCDCNGNSNEC---------LDGS--GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
EC CDCNG+S C G+ G C +C+ +T G++CE+C Y + GA
Sbjct: 312 ECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGAS 371
Query: 127 --QFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTC 184
+ C C C P A C G +C+C E+ G C+ C PG+ G C
Sbjct: 372 IQETCISCECD-PDGAVPGAPCDPVTG--QCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Query: 185 KKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCG 244
+CDC N + CDE +G+C CL N G KC++CAP Y+ + C C C
Sbjct: 429 HRCDC--NILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACD 484
Query: 245 -----GGPCDSVTGEC-LEEGF 260
C+ TG+C EGF
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGF 506
Score = 93.2 bits (230), Expect = 2e-18
Identities = 175/784 (22%), Positives = 297/784 (37%), Gaps = 134/784 (17%)
Query: 79 CVPCDCN--GNSNE--CLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPC 134
C CDCN G+ + C + SG C+ C N G C++C Y G Q C+PC C
Sbjct: 428 CHRCDCNILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAP-YHWKLASG--QGCEPCAC 483
Query: 135 PLPHLANFAESCYRKNGAVRCICNENYAGPNCE-----RCAPGYYGNPLLIGSTCKKCDC 189
PH + + C + G +C C E + G C +C YG+ + + C+ CDC
Sbjct: 484 D-PH-NSLSPQCNQFTG--QCPCREGFGGLMCSAAAIRQCPDRTYGD---VATGCRACDC 536
Query: 190 S--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGP 247
G P CD+ +G+C C TG +C++C GY + C C+ P
Sbjct: 537 DFRGTEGPG-----CDKASGRCL-CRPGLTGPRCDQCQRGYCNRYPV---CVACH----P 583
Query: 248 CDSVTGECLEE---GFEPPTGCDKCVWD---LTDALRLAALSIEEGKSGVLSV----SSG 297
C L E F +W L D R A I + KS + + SS
Sbjct: 584 CFQTYDADLREQALRFGRLRNATASLWSGPGLED--RGLASRILDAKSKIEQIRAVLSSP 641
Query: 298 AAAHRHVNEINATIYLLKTKLS--------ERENQYALRKIQ-INNAENTMKSLLSDVEE 348
A + V ++ + I L+ L E E R ++ ++ + N + ++ E
Sbjct: 642 AVTEQEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKRE 701
Query: 349 LVEKENQASRKGQL--------VQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGE 400
EK + A G ++ ++ +S+L++Q D R + + + + G
Sbjct: 702 QFEKISSADPSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGG 761
Query: 401 EHELSPKEISEKLVLAQKMLEEIRSRQPFFTQ-----RELVDEEADEAYELLSQAESWQR 455
S KLV + + + P F + R++ EL Q ++
Sbjct: 762 TG-------SPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQ-DNGTA 813
Query: 456 LHNETRTLFP----------VVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAAR 505
+ R + P V EQL +NA+L ++ +R AE+ +
Sbjct: 814 CGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQ-------MIRAAEESASQIQSS 866
Query: 506 QRDHEKQQERVREQMEV----VNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGA 561
+ E Q R QME + + D LT P + + ++ + ++ D A
Sbjct: 867 AQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSA 926
Query: 562 -----KSELQVKLSNLSNLSHDLVQ--EAIDHAQDLQQEANELSRKLHSSDMNGLVQKAL 614
+E+Q + L N+ L Q + I A+ LQ EA E + H+ + G V+ +
Sbjct: 927 TVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHA--VEGQVEDVV 984
Query: 615 DASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQA 674
N+ + V + EA +T + + I D V+ + + + ++ Q +
Sbjct: 985 --GNLRQGTV-ALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWT 1041
Query: 675 KAESSSDEAVADTSRRVGGALARKSALKTRLS-----DAVKQLQAAERGDAQQRLGQSRL 729
+ E +A + V + A + LS + +KQ A + + RLGQS +
Sbjct: 1042 RMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYA----ELKDRLGQSSM 1097
Query: 730 ITEEANR-------------TTMEVQQATAPMANNLTNWSQ--NLQHFDSSAYNTAVNSA 774
+ E+ R TME+ M L SQ L+ D + V
Sbjct: 1098 LGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQI 1157
Query: 775 RDAV 778
RD +
Sbjct: 1158 RDHI 1161
Score = 92.0 bits (227), Expect = 5e-18
Identities = 50/135 (37%), Positives = 63/135 (46%), Gaps = 20/135 (14%)
Query: 155 CICNENYAGPNCERCAPGYYGNPLLIGS-----TCKKCDCSGNS-----DPNLIFEDCDE 204
C+C N AGPNCERCAP Y P C++CDC+G+S DP +
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 205 VTGQCRNCLRNTTGFKCERCAPGYYGDAR----IAKNCAVCNCG------GGPCDSVTGE 254
G C NC +T G CERC Y+ + R I + C C C G PCD VTG+
Sbjct: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398
Query: 255 CLEEGFEPPTGCDKC 269
C+ + CD C
Sbjct: 399 CVCKEHVQGERCDLC 413
Score = 84.3 bits (207), Expect = 1e-15
Identities = 67/225 (29%), Positives = 90/225 (40%), Gaps = 46/225 (20%)
Query: 82 CDCNGNSNECLDGSG-------------YCVHCQRNTTGEHCEKCLDGYIGDSIRGA--- 125
C C+G+++ C G CV CQ NT G +CE+C Y R A
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 126 -PQFCQPCPCPLPHLANFAESCY----------RKNGAVRCICNENYAGPNCERCAPGYY 174
CQ C C +E+C+ G V C ++ G NCERC Y+
Sbjct: 309 DAHECQRCDC-----NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363
Query: 175 GN---PLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG- 230
N I TC C+C + D + CD VTGQC C + G +C+ C PG+ G
Sbjct: 364 RNRRPGASIQETCISCEC--DPDGAVPGAPCDPVTGQC-VCKEHVQGERCDLCKPGFTGL 420
Query: 231 DARIAKNCAVCNCG------GGPCDSVTGECLEEGFEPPTGCDKC 269
+ C C+C PCD +G CL CD+C
Sbjct: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQC 465
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 18/121 (14%)
Query: 62 PAAEKCNAGFFHTLSGE-CVPCDC---NGNSNECLDGSGYCVHCQRNTTGEHCE-----K 112
P ++C + SG+ C PC C N S +C +G C C+ G C +
Sbjct: 460 PKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCP-CREGFGGLMCSAAAIRQ 518
Query: 113 CLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172
C D GD G C+ C C C + +G RC+C GP C++C G
Sbjct: 519 CPDRTYGDVATG----CRACDCDFR--GTEGPGCDKASG--RCLCRPGLTGPRCDQCQRG 570
Query: 173 Y 173
Y
Sbjct: 571 Y 571
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 92.4 bits (228), Expect = 4e-18
Identities = 61/219 (27%), Positives = 88/219 (40%), Gaps = 38/219 (17%)
Query: 79 CVPCDCNGNSNEC--------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGD--SI 122
C PC CN +S C G G C C+ NTTG +CE C D + +
Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGAD 631
Query: 123 RGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGS 182
A C+PC C N + C + G +C C + +G C +C G+Y L
Sbjct: 632 PSAIDVCKPCDCDTVGTRNGSILCDQIGG--QCNCKRHVSGRQCNQCQNGFYNLQELDPD 689
Query: 183 TCKKCDC--SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGY-----YGDARIA 235
C C+C SG D ++ C + +GQC+ C N G +C+ C G+ + D
Sbjct: 690 GCSPCNCNTSGTVDGDI---TCHQNSGQCK-CKANVIGLRCDHCNFGFKFLRSFNDV--- 742
Query: 236 KNCAVCNCG-----GGPCDSVTGECLEEGFEPPTGCDKC 269
C C C C+ +G+C + CD C
Sbjct: 743 -GCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTC 780
Score = 87.8 bits (216), Expect = 9e-17
Identities = 66/230 (28%), Positives = 98/230 (42%), Gaps = 47/230 (20%)
Query: 74 TLSGECVPCDCNGNSNEC-LDGSGYCVHCQRN--TTGEHCEKCLDGYIGDSIRGAPQF-- 128
T+SG C C+G+++ C Y C + T G HC++CL Y R Q
Sbjct: 513 TISGRC---QCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYA 569
Query: 129 --CQPCPCPLPHLANFAESC-------------YRKNGAVRCICNENYAGPNCERCAPGY 173
C+PC C + ++SC +R G V C N G NCE C +
Sbjct: 570 FNCKPCQC-----NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYF 624
Query: 174 Y----GNPLLIGSTCKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPG 227
+ +P I CK CDC G + +++ CD++ GQC NC R+ +G +C +C G
Sbjct: 625 FRQVGADPSAI-DVCKPCDCDTVGTRNGSIL---CDQIGGQC-NCKRHVSGRQCNQCQNG 679
Query: 228 YYGDARI-AKNCAVCNC-------GGGPCDSVTGECLEEGFEPPTGCDKC 269
+Y + C+ CNC G C +G+C + CD C
Sbjct: 680 FYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHC 729
Score = 87.0 bits (214), Expect = 1e-16
Identities = 65/224 (29%), Positives = 95/224 (42%), Gaps = 35/224 (15%)
Query: 65 EKCNAGFFHTLSGE---CVPCDCN--GNSNE-CLDGSGYCVHCQRNTTGEHCEKCLDGYI 118
+ CN GF S C PC CN G+ N+ C SG C C++ G C+ C + +
Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAKGLQCDTCRENFY 785
Query: 119 GDSIRGAPQFCQPCPC----PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
G + C+ C C LP C K G +CIC N G C +C G +
Sbjct: 786 GLDVTN----CKACDCDTAGSLP-----GTVCNAKTG--QCICKPNVEGRQCNKCLEGNF 834
Query: 175 GNPLLIGSTCKKCDC--SGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-D 231
C C+C +G + +L+ C++ TGQC C TG +C +C P Y
Sbjct: 835 YLRQNNSFLCLPCNCDKTGTINGSLL---CNKSTGQC-PCKLGVTGLRCNQCEPHRYNLT 890
Query: 232 ARIAKNCAVCNCG------GGPCDSVTGECLEEGFEPPTGCDKC 269
++C +C C G CD ++G+CL C++C
Sbjct: 891 IDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQC 934
Score = 87.0 bits (214), Expect = 1e-16
Identities = 66/222 (29%), Positives = 91/222 (40%), Gaps = 30/222 (13%)
Query: 66 KCNAGFFHTLSGE---CVPCDCN-----GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117
KC G F+ C+PC+C+ S C +G C C+ TG C +C
Sbjct: 828 KCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCP-CKLGVTGLRCNQCEPHR 886
Query: 118 IGDSIRGAPQFCQPCPCP----LPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGY 173
+I Q CQ C C LP C +G +C+C N G C +C PG+
Sbjct: 887 YNLTIDNF-QHCQMCECDSLGTLP-----GTICDPISG--QCLCVPNRQGRRCNQCQPGF 938
Query: 174 YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDAR 233
Y +P + C C C N I C+ +TGQC + G +C++C Y+G
Sbjct: 939 YISPGN-ATGCLPCSCHTTGAVNHI---CNSLTGQCVCQDASIAGQRCDQCKDHYFGFDP 994
Query: 234 IAKNCAVCNCG-----GGPCDSVTGECLEEGFEPPTGCDKCV 270
C CNC C VTG+C + F + CD CV
Sbjct: 995 QTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036
Score = 66.6 bits (161), Expect = 2e-10
Identities = 48/153 (31%), Positives = 65/153 (42%), Gaps = 17/153 (11%)
Query: 79 CVPCDCNG----NSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPC 134
C C+C+ C SG C+ C N G C +C G+ G C PC C
Sbjct: 897 CQMCECDSLGTLPGTICDPISGQCL-CVPNRQGRRCNQCQPGFYISP--GNATGCLPCSC 953
Query: 135 PLPHLANFAESCYRKNGAVRCICNE-NYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNS 193
N C G +C+C + + AG C++C Y+G G C+ C+C +
Sbjct: 954 HTTGAVNHI--CNSLTG--QCVCQDASIAGQRCDQCKDHYFGFDPQTGR-CQPCNCHLSG 1008
Query: 194 DPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAP 226
N E C VTGQC C + TG KC+ C P
Sbjct: 1009 ALN---ETCHLVTGQCF-CKQFVTGSKCDACVP 1037
Score = 59.7 bits (143), Expect = 3e-08
Identities = 35/112 (31%), Positives = 52/112 (46%), Gaps = 13/112 (11%)
Query: 66 KCNAGFFHTLSGE--CVPCDCNGN---SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG- 119
+C GF+ + C+PC C+ ++ C +G CV + G+ C++C D Y G
Sbjct: 933 QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGF 992
Query: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAP 171
D G CQPC C L N E+C+ G +C C + G C+ C P
Sbjct: 993 DPQTGR---CQPCNCHLSGALN--ETCHLVTG--QCFCKQFVTGSKCDACVP 1037
>gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]
Length = 1547
Score = 87.4 bits (215), Expect = 1e-16
Identities = 163/849 (19%), Positives = 315/849 (37%), Gaps = 136/849 (16%)
Query: 1045 FDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFY 1104
F GS Y D+++ + +T NGL+L + + L ++NG + +
Sbjct: 319 FKGSEYFCY-DLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVI 377
Query: 1105 DFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMIL---VVDRRHVK---SMDNEK 1158
+ G +E + ND +H++ + + + + +V++ H S+D
Sbjct: 378 NLGSGAFEALVEPV--NGKFNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGIL 435
Query: 1159 MKIPFTD-----------IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNL 1207
+T Y+GG+P S A P+ NF GC+K ++ D L
Sbjct: 436 TTTGYTQEDYTMLGSDDFFYVGGSP-----STADLPGSPVSNNFMGCLKEVVYKNNDVRL 490
Query: 1208 -LEQTETLG---------VGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFR 1257
L + G V + C + + + +SFI S+ K + F+FR
Sbjct: 491 ELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFI-SLPKWNAKKTGSISFDFR 549
Query: 1258 TLQPNGLLFYYASGS--------------DVFSISLDNGTV--IMDVKG--IKVQSVDKQ 1299
T +PNGL+ + D F+I + +G + ++D+ IK++++ K+
Sbjct: 550 TTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKK 609
Query: 1300 YNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSP------- 1352
NDG + V + V+ R P + +I + + Y GG P
Sbjct: 610 VNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDL---DDELYLGGLPENKAGLV 666
Query: 1353 ------ISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLH 1406
+ + GCI + + +D+ + T V S
Sbjct: 667 FPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSC-------------- 712
Query: 1407 KKGKNLSKPKASQN-KKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQY 1465
K +KP S K G +D W+ +L S Y
Sbjct: 713 --SKETAKPCLSNPCKNNGMCRDG--WNRYVCDCSGTG-------YLGRSCEREATVLSY 761
Query: 1466 GGTANSRQEFE---HLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRL 1522
G+ + + H + + S+R R++ ++G++ + ++ D + L L GR+
Sbjct: 762 DGSMFMKIQLPVVMHTEAE-----DVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRV 816
Query: 1523 VYMFNVGHKKLKIRSQE---------KYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLP 1573
N+ ++ S + ND WH V +R S +L +D + + +
Sbjct: 817 KLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMA 876
Query: 1574 PTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPC 1633
+ I G + + + +V N F G L +L NG + + + C
Sbjct: 877 GDHTRLEFHN-IETGIITERRYLSSVPSN----FIGHLQSLTFNGMAYIDLCKNGDIDYC 931
Query: 1634 -------FEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNG 1686
F + F T+ YV L + + F+ + S G +++
Sbjct: 932 ELNARFGFRNIIADPVTFKTKSSYVAL-ATLQAYTSMHLFFQFKTTSLDGLILYNSGDGN 990
Query: 1687 EYLNVHMKNGQV--IVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRD-SNVVQLDVDSE 1743
+++ V + G + + + NG S + L D +WH + + RD SN+ + +D++
Sbjct: 991 DFIVVELVKGYLHYVFDLGNGANLIKGS--SNKPLNDNQWHNVMISRDTSNLHTVKIDTK 1048
Query: 1744 VNHVVGPLNPKPIDHREPVFVGGVPESLL--TPRLAPSKP-FTGCIRHFVIDGH-PVSFS 1799
+ + + +D + +++GGV + P+L +K F GC+ ++G P S
Sbjct: 1049 ITTQI-TAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLIS 1107
Query: 1800 KAALVSGAV 1808
A +G +
Sbjct: 1108 DALFCNGQI 1116
Score = 56.2 bits (134), Expect = 3e-07
Identities = 87/371 (23%), Positives = 143/371 (38%), Gaps = 48/371 (12%)
Query: 886 EYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIER-------VGKHGKV 938
+Y+ LA+KN + V NLG+ E ++ + VK+ R +G H V
Sbjct: 362 DYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIG-HAMV 420
Query: 939 FLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGC 998
S++ + + G D ++L D FYVGG PS LP S F+GC
Sbjct: 421 NKLHCSVTISVDGILTTTGYTQEDYTMLG---SDDFFYVGGSPSTADLPGSPVSNNFMGC 477
Query: 999 LELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITR 1058
L+ N+ + L + DP + +AF A+ D +
Sbjct: 478 LKEVVYKNNDVRLELSRLAKQGDPKMKI---HGVVAFKCENVAT--LDPITFETPESFIS 532
Query: 1059 RGKFG--QVTRFDIEVRTPADNGLILL---------------MVNGSMFFRLEMRNGYLH 1101
K+ + + RT NGLIL M+ FF +EM +G+L+
Sbjct: 533 LPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVD-FFAIEMLDGHLY 591
Query: 1102 VFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKI 1161
+ D G G + ++ LKK +ND +++ + I V R + E +
Sbjct: 592 LLLDMG--SGTIKIKALLKK--VNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEIL 647
Query: 1162 PFTD-IYIGGAPPE----ILQSRALRAHLPLDINFRGCMKG--FQFQKKDF-NLLEQTET 1213
D +Y+GG P + + A L+ + GC++ Q KD + E T
Sbjct: 648 DLDDELYLGGLPENKAGLVFPTEVWTA--LLNYGYVGCIRDLFIDGQSKDIRQMAEVQST 705
Query: 1214 LGVGYGCPEDS 1224
GV C +++
Sbjct: 706 AGVKPSCSKET 716
Score = 50.1 bits (118), Expect = 2e-05
Identities = 35/144 (24%), Positives = 68/144 (47%), Gaps = 7/144 (4%)
Query: 1485 KSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAH-GRLVYMFNV-GHKKLKIRSQEKYN 1542
+S+ S +L+TRS+ G++ Y D+ DF+ L L GRL F++ + + + N
Sbjct: 51 ESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVN 110
Query: 1543 DGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAP--GKAVKNVQ 1600
DG WH V R+ + L ID + + + +++GG+ P A +
Sbjct: 111 DGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLT 170
Query: 1601 INSIYS---FSGCLSNLQLNGASI 1621
+ S+ F G + ++++N + +
Sbjct: 171 LASVREREPFKGWIRDVRVNSSQV 194
Score = 47.8 bits (112), Expect = 1e-04
Identities = 145/764 (18%), Positives = 275/764 (35%), Gaps = 143/764 (18%)
Query: 884 KKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVP 943
K ++ + + + +L + ++G+ ++I K V+ Y V +R G+ G + +
Sbjct: 577 KVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYH--VDFQRDGRSGTISVNTL 634
Query: 944 SLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSN-------FKLPTSLNLPGFV 996
TA G+ +LDLD E Y+GG+P N ++ T+L G+V
Sbjct: 635 RTPYTAP----------GESEILDLDDE---LYLGGLPENKAGLVFPTEVWTALLNYGYV 681
Query: 997 GCLE---LATLNNDVISLYNFKHIYNMDPSTSVPCARDKLA-------FTQSRAASYFFD 1046
GC+ + + D+ + + + PS S A+ L+ + Y D
Sbjct: 682 GCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCD 741
Query: 1047 --GSGY---AVVRDITRRGKFGQV------------TRFDIEVRTPADNGLILLMVNGSM 1089
G+GY + R+ T G + D+ +R + +LM S
Sbjct: 742 CSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSR 801
Query: 1090 ----FFRLEMRNGYLHVFYDF-------GFSGGPVHLEDTLKKAQINDAKYHEISIIYHN 1138
RLE+ G + + + S GP E +ND ++H + ++
Sbjct: 802 DSADTLRLELDAGRVKLTVNLDCIRINCNSSKGP---ETLFAGYNLNDNEWHTVRVV-RR 857
Query: 1139 DKKMILVVDRRHVKS--MDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMK 1196
K + L VD + + M + ++ F +I G I+ R + +P NF G ++
Sbjct: 858 GKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETG-----IITERRYLSSVPS--NFIGHLQ 910
Query: 1197 GFQF---------QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFF 1247
F + D + E G ++I+ F +S ++ + +
Sbjct: 911 SLTFNGMAYIDLCKNGDIDYCELNARFGFR------NIIADPVTFKTKSSYVALATLQAY 964
Query: 1248 DGFEGGFNFRTLQPNGLLFYYAS-GSDVFSISLDNGTV--IMDV---KGIKVQSVDKQYN 1301
F F+T +GL+ Y + G+D + L G + + D+ + S +K N
Sbjct: 965 TSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLN 1024
Query: 1302 DGLSHFVISSVSPTRYELIVDKSRV------GSKNPTKGKIEQTQASEKKFYFGGSPISA 1355
D H V+ S + + +++ G++N K+ Y +
Sbjct: 1025 DNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVH 1084
Query: 1356 QYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKP 1415
F GC+++ VD + + D + S LF + + P
Sbjct: 1085 AKEGFQGCLAS-----VDLNGRLPD----------------LISDALFCNGQIERGCEGP 1123
Query: 1416 KASQNKKGGKSKDA--PSWDPVALKL-------PERNTPRNSHCHLSNSPRAIEHAYQYG 1466
+ + ++ WD + P N P ++ + Y++
Sbjct: 1124 STTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQI---TYKWP 1180
Query: 1467 GTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMF 1526
+ L F + ++ +R SS G+ D++ L + G++ F
Sbjct: 1181 PNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGL---------GDYLELHIHQGKIGVKF 1231
Query: 1527 NVGHKKLKIR-SQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLE 1569
NVG + I S NDG +H V F R + L +D V+E
Sbjct: 1232 NVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIE 1275
Score = 47.4 bits (111), Expect = 1e-04
Identities = 71/390 (18%), Positives = 140/390 (35%), Gaps = 74/390 (18%)
Query: 1484 AKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQE---K 1540
+ + ++ +T +G++ + + D++ L L +G + + N+G + + K
Sbjct: 337 SSDEITLSFKTLQRNGLMLHTG--KSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGK 394
Query: 1541 YNDGLWHDVIFIRE---------------RSSGRLVIDGLRVLEESLPPTEATWKIKGP- 1584
+ND WHDV R S + +DG+ + T+ + + G
Sbjct: 395 FNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILT---TTGYTQEDYTMLGSD 451
Query: 1585 --IYLGGVA-----PGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFS-------- 1629
Y+GG PG V N +F GCL + + +
Sbjct: 452 DFFYVGGSPSTADLPGSPVSN-------NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMK 504
Query: 1630 -----VTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHS- 1683
C F T ++ L + +N I+F+ R +G ++ H
Sbjct: 505 IHGVVAFKCENVATLDPITFETPESFISLPK-WNAKKTGSISFDFRTTEPNGLILFSHGK 563
Query: 1684 ------------VNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIR 1731
+ ++ + M +G + + ++ G K+ + DG W+ + R
Sbjct: 564 PRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKK-VNDGEWYHVDFQR 622
Query: 1732 DSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPES---LLTP----RLAPSKPFTG 1784
D + V++ P + +D + +++GG+PE+ L+ P + + G
Sbjct: 623 DGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVG 682
Query: 1785 CIRHFVIDGHPVSFSKAALVSGAVSIN-SC 1813
CIR IDG + A V + SC
Sbjct: 683 CIRDLFIDGQSKDIRQMAEVQSTAGVKPSC 712
Score = 35.8 bits (81), Expect = 0.39
Identities = 37/142 (26%), Positives = 61/142 (42%), Gaps = 21/142 (14%)
Query: 1060 GKFGQVTRF-----------DIEVRTPADNGLILLMVNGSMFFRLEM---RNGYLHVFYD 1105
G GQ TRF +++T + GL+L + LE+ R G L + +
Sbjct: 35 GAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFS 94
Query: 1106 FGFSGGPVHLEDTLKKAQINDAKYHEISII--YHNDKKMILVVDRRHVKSMDNEKMKIPF 1163
F P L L +ND +H + I + N I V+ + V+ + F
Sbjct: 95 I-FCAEPATL---LADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVF 150
Query: 1164 TDIYIGGAPPEILQSRALRAHL 1185
+ +++GG PPE L++ AL+ L
Sbjct: 151 SGLFVGGLPPE-LRAAALKLTL 171
>gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]
Length = 1477
Score = 87.4 bits (215), Expect = 1e-16
Identities = 162/843 (19%), Positives = 311/843 (36%), Gaps = 131/843 (15%)
Query: 1045 FDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFY 1104
F GS Y D+++ + +T NGL+L + + L ++NG + +
Sbjct: 286 FKGSEYFCY-DLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVI 344
Query: 1105 DFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKIPFT 1164
+ G +E + ND +H++ + N ++ + S+D +T
Sbjct: 345 NLGSGAFEALVEPV--NGKFNDNAWHDVKVT-RNLRQHSGIGHAMVTISVDGILTTTGYT 401
Query: 1165 D-----------IYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNL-LEQTE 1212
Y+GG+P S A P+ NF GC+K ++ D L L +
Sbjct: 402 QEDYTMLGSDDFFYVGGSP-----STADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLA 456
Query: 1213 TLG---------VGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQPNG 1263
G V + C + + + +SFI S+ K + F+FRT +PNG
Sbjct: 457 KQGDPKMKIHGVVAFKCENVATLDPITFETPESFI-SLPKWNAKKTGSISFDFRTTEPNG 515
Query: 1264 LLFYYASGS--------------DVFSISLDNGTV--IMDVKG--IKVQSVDKQYNDGLS 1305
L+ + D F+I + +G + ++D+ IK++++ K+ NDG
Sbjct: 516 LILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEW 575
Query: 1306 HFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSP------------- 1352
+ V + V+ R P + +I + + Y GG P
Sbjct: 576 YHVDFQRDGRSGTISVNTLRTPYTAPGESEILDL---DDELYLGGLPENKAGLVFPTEVW 632
Query: 1353 ISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNL 1412
+ + GCI + + +D+ + T V S K
Sbjct: 633 TALLNYGYVGCIRDLFIDGQSKDIRQMAEVQSTAGVKPSC----------------SKET 676
Query: 1413 SKPKASQN-KKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANS 1471
+KP S K G +D W+ +L S Y G+
Sbjct: 677 AKPCLSNPCKNNGMCRDG--WNRYVCDCSGTG-------YLGRSCEREATVLSYDGSMFM 727
Query: 1472 RQEFE---HLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNV 1528
+ + H + + S+R R++ ++G++ + ++ D + L L GR+ N+
Sbjct: 728 KIQLPVVMHTEAE-----DVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVKLTVNL 782
Query: 1529 GHKKLKIRSQE---------KYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATW 1579
++ S + ND WH V +R S +L +D + + +
Sbjct: 783 DCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRL 842
Query: 1580 KIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPC------ 1633
+ I G + + + +V N F G L +L NG + + + C
Sbjct: 843 EFHN-IETGIITERRYLSSVPSN----FIGHLQSLTFNGMAYIDLCKNGDIDYCELNARF 897
Query: 1634 -FEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVH 1692
F + F T+ YV L + + F+ + S G +++ +++ V
Sbjct: 898 GFRNIIADPVTFKTKSSYVAL-ATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVE 956
Query: 1693 MKNGQV--IVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRD-SNVVQLDVDSEVNHVVG 1749
+ G + + + NG S + L D +WH + + RD SN+ + +D+++ +
Sbjct: 957 LVKGYLHYVFDLGNGANLIKGS--SNKPLNDNQWHNVMISRDTSNLHTVKIDTKITTQI- 1013
Query: 1750 PLNPKPIDHREPVFVGGVPESLL--TPRLAPSKP-FTGCIRHFVIDGH-PVSFSKAALVS 1805
+ +D + +++GGV + P+L +K F GC+ ++G P S A +
Sbjct: 1014 TAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCN 1073
Query: 1806 GAV 1808
G +
Sbjct: 1074 GQI 1076
Score = 58.2 bits (139), Expect = 7e-08
Identities = 88/371 (23%), Positives = 144/371 (38%), Gaps = 55/371 (14%)
Query: 886 EYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIER-------VGKHGKV 938
+Y+ LA+KN + V NLG+ E ++ + VK+ R +G H V
Sbjct: 329 DYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIG-HAMV 387
Query: 939 FLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGC 998
++V + +T G D ++L D FYVGG PS LP S F+GC
Sbjct: 388 TISVDGILTTT-------GYTQEDYTMLG---SDDFFYVGGSPSTADLPGSPVSNNFMGC 437
Query: 999 LELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITR 1058
L+ N+ + L + DP + +AF A+ D +
Sbjct: 438 LKEVVYKNNDVRLELSRLAKQGDPKMKI---HGVVAFKCENVAT--LDPITFETPESFIS 492
Query: 1059 RGKFG--QVTRFDIEVRTPADNGLILL---------------MVNGSMFFRLEMRNGYLH 1101
K+ + + RT NGLIL M+ FF +EM +G+L+
Sbjct: 493 LPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVD-FFAIEMLDGHLY 551
Query: 1102 VFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKI 1161
+ D G G + ++ LKK +ND +++ + I V R + E +
Sbjct: 552 LLLDMG--SGTIKIKALLKK--VNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEIL 607
Query: 1162 PFTD-IYIGGAPPE----ILQSRALRAHLPLDINFRGCMKG--FQFQKKDF-NLLEQTET 1213
D +Y+GG P + + A L+ + GC++ Q KD + E T
Sbjct: 608 DLDDELYLGGLPENKAGLVFPTEVWTA--LLNYGYVGCIRDLFIDGQSKDIRQMAEVQST 665
Query: 1214 LGVGYGCPEDS 1224
GV C +++
Sbjct: 666 AGVKPSCSKET 676
Score = 53.1 bits (126), Expect = 2e-06
Identities = 157/817 (19%), Positives = 293/817 (35%), Gaps = 155/817 (18%)
Query: 884 KKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVP 943
K ++ + + + +L + ++G+ ++I K V+ Y V +R G+ G + +
Sbjct: 537 KVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYH--VDFQRDGRSGTISVNTL 594
Query: 944 SLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSN-------FKLPTSLNLPGFV 996
TA G+ +LDLD E Y+GG+P N ++ T+L G+V
Sbjct: 595 RTPYTAP----------GESEILDLDDE---LYLGGLPENKAGLVFPTEVWTALLNYGYV 641
Query: 997 GCLE---LATLNNDVISLYNFKHIYNMDPSTSVPCARDKLA-------FTQSRAASYFFD 1046
GC+ + + D+ + + + PS S A+ L+ + Y D
Sbjct: 642 GCIRDLFIDGQSKDIRQMAEVQSTAGVKPSCSKETAKPCLSNPCKNNGMCRDGWNRYVCD 701
Query: 1047 --GSGY---AVVRDITRRGKFGQV------------TRFDIEVRTPADNGLILLMVNGSM 1089
G+GY + R+ T G + D+ +R + +LM S
Sbjct: 702 CSGTGYLGRSCEREATVLSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSR 761
Query: 1090 ----FFRLEMRNGYLHVFYDF-------GFSGGPVHLEDTLKKAQINDAKYHEISIIYHN 1138
RLE+ G + + + S GP E +ND ++H + ++
Sbjct: 762 DSADTLRLELDAGRVKLTVNLDCIRINCNSSKGP---ETLFAGYNLNDNEWHTVRVV-RR 817
Query: 1139 DKKMILVVDRRHVKS--MDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMK 1196
K + L VD + + M + ++ F +I G I+ R + +P NF G ++
Sbjct: 818 GKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETG-----IITERRYLSSVPS--NFIGHLQ 870
Query: 1197 GFQF---------QKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFF 1247
F + D + E G ++I+ F +S ++ + +
Sbjct: 871 SLTFNGMAYIDLCKNGDIDYCELNARFGFR------NIIADPVTFKTKSSYVALATLQAY 924
Query: 1248 DGFEGGFNFRTLQPNGLLFYYAS-GSDVFSISLDNGTV--IMDV---KGIKVQSVDKQYN 1301
F F+T +GL+ Y + G+D + L G + + D+ + S +K N
Sbjct: 925 TSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLN 984
Query: 1302 DGLSHFVISSVSPTRYELIVDKSRV------GSKNPTKGKIEQTQASEKKFYFGGSPISA 1355
D H V+ S + + +++ G++N K+ Y +
Sbjct: 985 DNQWHNVMISRDTSNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVH 1044
Query: 1356 QYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKP 1415
F GC+++ VD + + D + S LF + + P
Sbjct: 1045 AKEGFQGCLAS-----VDLNGRLPD----------------LISDALFCNGQIERGCEGP 1083
Query: 1416 KASQNKKGGKSKDA--PSWDPVALKL-------PERNTPRNSHCHLSNSPRAIEHAYQYG 1466
+ + ++ WD + P N P ++ + Y++
Sbjct: 1084 STTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQI---TYKWP 1140
Query: 1467 GTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMF 1526
+ L F + ++ +R SS G+ D++ L + G++ F
Sbjct: 1141 PNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGL---------GDYLELHIHQGKIGVKF 1191
Query: 1527 NVGHKKLKIR-SQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEAT-WKIKGP 1584
NVG + I S NDG +H V F R + L +D V+E + T + +
Sbjct: 1192 NVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQAT 1251
Query: 1585 IYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASI 1621
I +GG G+ F G LS L NG +
Sbjct: 1252 IIIGGKEQGQ-----------PFQGQLSGLYYNGLKV 1277
Score = 50.1 bits (118), Expect = 2e-05
Identities = 35/144 (24%), Positives = 68/144 (47%), Gaps = 7/144 (4%)
Query: 1485 KSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAH-GRLVYMFNV-GHKKLKIRSQEKYN 1542
+S+ S +L+TRS+ G++ Y D+ DF+ L L GRL F++ + + + N
Sbjct: 51 ESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVN 110
Query: 1543 DGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAP--GKAVKNVQ 1600
DG WH V R+ + L ID + + + +++GG+ P A +
Sbjct: 111 DGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSGLFVGGLPPELRAAALKLT 170
Query: 1601 INSIYS---FSGCLSNLQLNGASI 1621
+ S+ F G + ++++N + +
Sbjct: 171 LASVREREPFKGWIRDVRVNSSQV 194
Score = 49.7 bits (117), Expect = 3e-05
Identities = 72/383 (18%), Positives = 142/383 (37%), Gaps = 67/383 (17%)
Query: 1484 AKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQE---K 1540
+ + ++ +T +G++ + + D++ L L +G + + N+G + + K
Sbjct: 304 SSDEITLSFKTLQRNGLMLHTG--KSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGK 361
Query: 1541 YNDGLWHDVIFIRE--RSSG------RLVIDGLRVLEESLPPTEATWKIKGP---IYLGG 1589
+ND WHDV R + SG + +DG+ + T+ + + G Y+GG
Sbjct: 362 FNDNAWHDVKVTRNLRQHSGIGHAMVTISVDGILT---TTGYTQEDYTMLGSDDFFYVGG 418
Query: 1590 VA-----PGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFS-------------VT 1631
PG V N +F GCL + + +
Sbjct: 419 SPSTADLPGSPVSN-------NFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAF 471
Query: 1632 PCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHS-------- 1683
C F T ++ L + +N I+F+ R +G ++ H
Sbjct: 472 KCENVATLDPITFETPESFISLPK-WNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDA 530
Query: 1684 -----VNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQL 1738
+ ++ + M +G + + ++ G K+ + DG W+ + RD +
Sbjct: 531 KHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALLKK-VNDGEWYHVDFQRDGRSGTI 589
Query: 1739 DVDSEVNHVVGPLNPKPIDHREPVFVGGVPES---LLTP----RLAPSKPFTGCIRHFVI 1791
V++ P + +D + +++GG+PE+ L+ P + + GCIR I
Sbjct: 590 SVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFI 649
Query: 1792 DGHPVSFSKAALVSGAVSIN-SC 1813
DG + A V + SC
Sbjct: 650 DGQSKDIRQMAEVQSTAGVKPSC 672
Score = 35.8 bits (81), Expect = 0.39
Identities = 37/142 (26%), Positives = 61/142 (42%), Gaps = 21/142 (14%)
Query: 1060 GKFGQVTRF-----------DIEVRTPADNGLILLMVNGSMFFRLEM---RNGYLHVFYD 1105
G GQ TRF +++T + GL+L + LE+ R G L + +
Sbjct: 35 GAEGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFS 94
Query: 1106 FGFSGGPVHLEDTLKKAQINDAKYHEISII--YHNDKKMILVVDRRHVKSMDNEKMKIPF 1163
F P L L +ND +H + I + N I V+ + V+ + F
Sbjct: 95 I-FCAEPATL---LADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVF 150
Query: 1164 TDIYIGGAPPEILQSRALRAHL 1185
+ +++GG PPE L++ AL+ L
Sbjct: 151 SGLFVGGLPPE-LRAAALKLTL 171
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,919,651
Number of Sequences: 37866
Number of extensions: 3237775
Number of successful extensions: 13867
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 123
Number of HSP's successfully gapped in prelim test: 674
Number of HSP's that attempted gapping in prelim test: 9629
Number of HSP's gapped (non-prelim): 2897
length of query: 1816
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1699
effective length of database: 13,817,196
effective search space: 23475416004
effective search space used: 23475416004
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.