Search of human proteins with 157388995

Search of human proteins with 157388995

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157388995 protein-L-isoaspartate (D-aspartate)
O-methyltransferase domain containing 2 isoform 1 [Homo sapiens]
         (361 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157388995 protein-L-isoaspartate (D-aspartate) O-methyltransf...   730   0.0  
gi|157388997 protein-L-isoaspartate (D-aspartate) O-methyltransf...   663   0.0  
gi|190360566 protein-L-isoaspartate (D-aspartate) O-methyltransf...   488   e-138
gi|239757983 PREDICTED: similar to protein-L-isoaspartate (D-asp...    97   2e-20
gi|239747889 PREDICTED: hypothetical protein XP_002346467 [Homo ...    97   2e-20
gi|239752574 PREDICTED: hypothetical protein XP_002348296 [Homo ...    88   1e-17
gi|239758102 PREDICTED: similar to protein-L-isoaspartate (D-asp...    84   3e-16
gi|239756570 PREDICTED: similar to protein-L-isoaspartate (D-asp...    81   2e-15
gi|239752577 PREDICTED: hypothetical protein XP_002348294 [Homo ...    81   2e-15
gi|239745549 PREDICTED: hypothetical protein XP_002343514 [Homo ...    81   2e-15
gi|226530908 protein-L-isoaspartate (D-aspartate) O-methyltransf...    55   1e-07
gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]         38   0.016
gi|166197690 neuronal guanine nucleotide exchange factor isoform...    34   0.18 
gi|166197688 neuronal guanine nucleotide exchange factor isoform...    34   0.18 
gi|187761324 shootin1 isoform a [Homo sapiens]                         33   0.30 
gi|50511340 shootin1 isoform b [Homo sapiens]                          33   0.30 
gi|123173772 tRNA(m1A58)-methyltransferase subunit TRM61 [Homo s...    32   0.88 
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo...    32   0.88 
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo...    32   0.88 
gi|12056465 fibrillarin [Homo sapiens]                                 31   1.5  
gi|61966703 NHS-like 2 [Homo sapiens]                                  31   1.5  
gi|16507239 wingless-type MMTV integration site family, member 6...    31   2.0  
gi|83716024 kinesin family member 21B [Homo sapiens]                   31   2.0  
gi|6912398 general transcription factor IIIC, polypeptide 3, 102...    31   2.0  
gi|4759208 TAO kinase 2 isoform 1 [Homo sapiens]                       30   3.4  
gi|45505130 TAO kinase 2 isoform 2 [Homo sapiens]                      30   3.4  
gi|23346412 cysteine-serine-rich nuclear protein 3 [Homo sapiens]      30   4.4  
gi|68077166 DnaJ homology subfamily A member 5 isoform 2 [Homo s...    30   4.4  
gi|5031703 Ras-GTPase-activating protein SH3-domain-binding prot...    30   4.4  
gi|38327552 Ras-GTPase-activating protein SH3-domain-binding pro...    30   4.4  

>gi|157388995 protein-L-isoaspartate (D-aspartate)
           O-methyltransferase domain containing 2 isoform 1 [Homo
           sapiens]
          Length = 361

 Score =  730 bits (1884), Expect = 0.0
 Identities = 361/361 (100%), Positives = 361/361 (100%)

Query: 1   MGGAVSAGEDNDELIDNLKEAQYIRTELVEQAFRAIDRADYYLEEFKENAYKDLAWKHGN 60
           MGGAVSAGEDNDELIDNLKEAQYIRTELVEQAFRAIDRADYYLEEFKENAYKDLAWKHGN
Sbjct: 1   MGGAVSAGEDNDELIDNLKEAQYIRTELVEQAFRAIDRADYYLEEFKENAYKDLAWKHGN 60

Query: 61  IHLSAPCIYSEVMEALDLQPGLSFLNLGSGTGYLSSMVGLILGPFGVNHGVELHSDVIEY 120
           IHLSAPCIYSEVMEALDLQPGLSFLNLGSGTGYLSSMVGLILGPFGVNHGVELHSDVIEY
Sbjct: 61  IHLSAPCIYSEVMEALDLQPGLSFLNLGSGTGYLSSMVGLILGPFGVNHGVELHSDVIEY 120

Query: 121 AKQKLDFFIRTSDSFDKFDFCEPSFVTGNCLEISPDCSQYDRVYCGAGVQKEHEEYMKNL 180
           AKQKLDFFIRTSDSFDKFDFCEPSFVTGNCLEISPDCSQYDRVYCGAGVQKEHEEYMKNL
Sbjct: 121 AKQKLDFFIRTSDSFDKFDFCEPSFVTGNCLEISPDCSQYDRVYCGAGVQKEHEEYMKNL 180

Query: 181 LKVGGILVMPLEEKLTKITRTGPSAWETKKILAVSFAPLIQPCHSESGKSRLVQLPPVAV 240
           LKVGGILVMPLEEKLTKITRTGPSAWETKKILAVSFAPLIQPCHSESGKSRLVQLPPVAV
Sbjct: 181 LKVGGILVMPLEEKLTKITRTGPSAWETKKILAVSFAPLIQPCHSESGKSRLVQLPPVAV 240

Query: 241 RSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETIVFLDKEVFAS 300
           RSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETIVFLDKEVFAS
Sbjct: 241 RSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETIVFLDKEVFAS 300

Query: 301 RISNPSDDNSCEDLEEERREEEEKTPPETKPDPPVNFLRQKVLSLPLPDPLKYYLLYYRE 360
           RISNPSDDNSCEDLEEERREEEEKTPPETKPDPPVNFLRQKVLSLPLPDPLKYYLLYYRE
Sbjct: 301 RISNPSDDNSCEDLEEERREEEEKTPPETKPDPPVNFLRQKVLSLPLPDPLKYYLLYYRE 360

Query: 361 K 361
           K
Sbjct: 361 K 361


>gi|157388997 protein-L-isoaspartate (D-aspartate)
           O-methyltransferase domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 334

 Score =  663 bits (1711), Expect = 0.0
 Identities = 334/361 (92%), Positives = 334/361 (92%), Gaps = 27/361 (7%)

Query: 1   MGGAVSAGEDNDELIDNLKEAQYIRTELVEQAFRAIDRADYYLEEFKENAYKDLAWKHGN 60
           MGGAVSAGEDNDELIDNLKEAQYIRTELVEQAFRAIDRADYYLEEFKENAYKDLAWKHGN
Sbjct: 1   MGGAVSAGEDNDELIDNLKEAQYIRTELVEQAFRAIDRADYYLEEFKENAYKDLAWKHGN 60

Query: 61  IHLSAPCIYSEVMEALDLQPGLSFLNLGSGTGYLSSMVGLILGPFGVNHGVELHSDVIEY 120
           IHLSAPCIYSEVMEALDLQPGLSFLNLGSGTGYLSSMVGLILGPFGVNHGVELHSDVIEY
Sbjct: 61  IHLSAPCIYSEVMEALDLQPGLSFLNLGSGTGYLSSMVGLILGPFGVNHGVELHSDVIEY 120

Query: 121 AKQKLDFFIRTSDSFDKFDFCEPSFVTGNCLEISPDCSQYDRVYCGAGVQKEHEEYMKNL 180
           AKQKLDFFIRTSDSFDKFDFCEPSFVTGNCLEISPDCSQYDRVYCGAGVQKEHEEYMKNL
Sbjct: 121 AKQKLDFFIRTSDSFDKFDFCEPSFVTGNCLEISPDCSQYDRVYCGAGVQKEHEEYMKNL 180

Query: 181 LKVGGILVMPLEEKLTKITRTGPSAWETKKILAVSFAPLIQPCHSESGKSRLVQLPPVAV 240
           LKVGGILVMPLEEK                           PCHSESGKSRLVQLPPVAV
Sbjct: 181 LKVGGILVMPLEEK---------------------------PCHSESGKSRLVQLPPVAV 213

Query: 241 RSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETIVFLDKEVFAS 300
           RSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETIVFLDKEVFAS
Sbjct: 214 RSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETIVFLDKEVFAS 273

Query: 301 RISNPSDDNSCEDLEEERREEEEKTPPETKPDPPVNFLRQKVLSLPLPDPLKYYLLYYRE 360
           RISNPSDDNSCEDLEEERREEEEKTPPETKPDPPVNFLRQKVLSLPLPDPLKYYLLYYRE
Sbjct: 274 RISNPSDDNSCEDLEEERREEEEKTPPETKPDPPVNFLRQKVLSLPLPDPLKYYLLYYRE 333

Query: 361 K 361
           K
Sbjct: 334 K 334


>gi|190360566 protein-L-isoaspartate (D-aspartate)
           O-methyltransferase domain containing 1 [Homo sapiens]
          Length = 357

 Score =  488 bits (1257), Expect = e-138
 Identities = 245/363 (67%), Positives = 296/363 (81%), Gaps = 8/363 (2%)

Query: 1   MGGAVSAGEDNDELIDNLKEAQYIRTELVEQAFRAIDRADYYLEEFKENAYKDLAWKHGN 60
           MGGAVSAGEDND+LIDNLKEAQYIRTE VEQAFRAIDR DYYLE +++NAYKDLAWKHGN
Sbjct: 1   MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGN 60

Query: 61  IHLSAPCIYSEVMEALDLQPGLSFLNLGSGTGYLSSMVGLILGPFGVNHGVELHSDVIEY 120
           IHLSAPCIYSEVMEAL LQPGLSFLNLGSGTGYLS+MVGLILGPFG+NHG+ELHSDV+EY
Sbjct: 61  IHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEY 120

Query: 121 AKQKLDFFIRTSDSFDKFDFCEPSFVTGNCLEISPDCSQYDRVYCGAGVQKEHEEYMKNL 180
           AK+KL+ FI+ SDSFDKF+FCEP+FV GNCL+I+ D  QYDR+YCGAGVQK+HE YMK L
Sbjct: 121 AKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKIL 180

Query: 181 LKVGGILVMPLEEKLTKITRTGPSAWETKKILAVSFAPLIQPCHSESGKSRLVQLPPVAV 240
           LKVGGILVMP+E++LT+I RTG + WE+K ILAVSFAPL+QP  +++GK   V LPP AV
Sbjct: 181 LKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGKPDSVGLPPCAV 240

Query: 241 RSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETIVFLDKEVFAS 300
           R+LQDLARI IR T++  I+ E  +K G   +  P+ KR+RV ++R+ T VF+  ++   
Sbjct: 241 RNLQDLARIYIRRTLRNFINDEMQAK-GIPQRAPPKRKRKRV-KQRINTYVFVGNQL--- 295

Query: 301 RISNPSDDNSCEDLEEERREEEEKTPPET-KP-DPPVNFLRQKVLSLPLPDPLKYYLLYY 358
            I  P D    E +EE+ +EEEEK   E  KP +PP N LR+K++ LPLP+ LK YL Y+
Sbjct: 296 -IPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKAYLTYF 354

Query: 359 REK 361
           R+K
Sbjct: 355 RDK 357


>gi|239757983 PREDICTED: similar to protein-L-isoaspartate
           (D-aspartate) O-methyltransferase domain containing 1
           [Homo sapiens]
          Length = 132

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 58/133 (43%), Positives = 85/133 (63%), Gaps = 8/133 (6%)

Query: 231 RLVQLPPVAVRSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETI 290
           R + +PP AVR+LQDLA I IR T++K  + E  +K G   +  P+ KR+R ++R + T 
Sbjct: 6   RALGIPPSAVRNLQDLALIYIRRTLRKFTNDEMQAK-GIPQRAPPKRKRKRAKQR-ITTY 63

Query: 291 VFLDKEVFASRISNPSDDNSCEDLEEERREEEEKTPPET-KPD-PPVNFLRQKVLSLPLP 348
           VF+  ++    I  P D    E++EE+ +EEEEK   E  KP+ PP N LR+K++ LPLP
Sbjct: 64  VFVGNQL----IPQPLDSEEDEEMEEDNKEEEEKDHSEAMKPEEPPQNLLREKIMKLPLP 119

Query: 349 DPLKYYLLYYREK 361
           + LK YL Y+R+K
Sbjct: 120 ESLKAYLTYFRDK 132


>gi|239747889 PREDICTED: hypothetical protein XP_002346467 [Homo
           sapiens]
          Length = 132

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 58/133 (43%), Positives = 85/133 (63%), Gaps = 8/133 (6%)

Query: 231 RLVQLPPVAVRSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETI 290
           R + +PP AVR+LQDLA I IR T++K  + E  +K G   +  P+ KR+R ++R + T 
Sbjct: 6   RALGIPPSAVRNLQDLALIYIRRTLRKFTNDEMQAK-GIPQRAPPKRKRKRAKQR-ITTY 63

Query: 291 VFLDKEVFASRISNPSDDNSCEDLEEERREEEEKTPPET-KPD-PPVNFLRQKVLSLPLP 348
           VF+  ++    I  P D    E++EE+ +EEEEK   E  KP+ PP N LR+K++ LPLP
Sbjct: 64  VFVGNQL----IPQPLDSEEDEEMEEDNKEEEEKDHSEAMKPEEPPQNLLREKIMKLPLP 119

Query: 349 DPLKYYLLYYREK 361
           + LK YL Y+R+K
Sbjct: 120 ESLKAYLTYFRDK 132


>gi|239752574 PREDICTED: hypothetical protein XP_002348296 [Homo
           sapiens]
          Length = 164

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 55/126 (43%), Positives = 79/126 (62%), Gaps = 8/126 (6%)

Query: 238 VAVRSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETIVFLDKEV 297
           V VR+LQDLARI IR T++  I+ E  +K G   +  P+ KR+RV++R + T VF+  ++
Sbjct: 45  VTVRNLQDLARIYIRCTLRNFINDEMQAK-GIPQRAPPKRKRKRVKQR-ITTYVFVGNQL 102

Query: 298 FASRISNPSDDNSCEDLEEERREEEEKTPPET-KPD-PPVNFLRQKVLSLPLPDPLKYYL 355
               I  P D    E +EE+ +EEEEK   E  KP+ PP N L +K++ L LP+ LK YL
Sbjct: 103 ----IPQPLDSEEDEKMEEDNKEEEEKDHSEAMKPEEPPQNLLTEKIMKLTLPESLKAYL 158

Query: 356 LYYREK 361
            Y+R+K
Sbjct: 159 TYFRDK 164


>gi|239758102 PREDICTED: similar to protein-L-isoaspartate
           (D-aspartate) O-methyltransferase domain containing 1
           [Homo sapiens]
          Length = 118

 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 52/122 (42%), Positives = 76/122 (62%), Gaps = 8/122 (6%)

Query: 242 SLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETIVFLDKEVFASR 301
           +LQDLARI IR T++  I+ E  +K G   +  P+ KR+RV++R + T VF+  ++    
Sbjct: 3   NLQDLARIYIRRTLRNFINDEMQAK-GIPQRAPPKRKRKRVKQR-ITTYVFVGNQL---- 56

Query: 302 ISNPSDDNSCEDLEEERREEEEKTPPET-KPD-PPVNFLRQKVLSLPLPDPLKYYLLYYR 359
           I  P D    E +EE+ +EEEEK   E  KP+ PP N L +K++ L LP+ LK YL Y+R
Sbjct: 57  IPQPLDSEEDEKMEEDNKEEEEKDHSEAMKPEEPPQNLLTEKIMKLTLPESLKAYLTYFR 116

Query: 360 EK 361
           +K
Sbjct: 117 DK 118


>gi|239756570 PREDICTED: similar to protein-L-isoaspartate
           (D-aspartate) O-methyltransferase domain containing 1
           [Homo sapiens]
          Length = 150

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 51/126 (40%), Positives = 75/126 (59%), Gaps = 8/126 (6%)

Query: 238 VAVRSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETIVFLDKEV 297
           + VR+LQDLA I IR T++  I+ E  +K G   +  P+ KR+RV++R     + +   V
Sbjct: 31  ITVRNLQDLALIYIRRTLRNFINDEMQAK-GIPQRAPPKRKRKRVKQR-----ITIYVCV 84

Query: 298 FASRISNPSDDNSCEDLEEERREEEEKTPPET-KPD-PPVNFLRQKVLSLPLPDPLKYYL 355
               I  P D    E++EE+ +EEEEK   E  KP+ PP   L +K++ LPLP+ LK YL
Sbjct: 85  CNQLILQPLDSEEDEEMEEDNKEEEEKDHSEAMKPEEPPQYLLTEKIMKLPLPESLKAYL 144

Query: 356 LYYREK 361
            Y+R+K
Sbjct: 145 TYFRDK 150


>gi|239752577 PREDICTED: hypothetical protein XP_002348294 [Homo
           sapiens]
          Length = 150

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 51/126 (40%), Positives = 75/126 (59%), Gaps = 8/126 (6%)

Query: 238 VAVRSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETIVFLDKEV 297
           + VR+LQDLA I IR T++  I+ E  +K G   +  P+ KR+RV++R     + +   V
Sbjct: 31  ITVRNLQDLALIYIRRTLRNFINDEMQAK-GIPQRAPPKRKRKRVKQR-----ITIYVCV 84

Query: 298 FASRISNPSDDNSCEDLEEERREEEEKTPPET-KPD-PPVNFLRQKVLSLPLPDPLKYYL 355
               I  P D    E++EE+ +EEEEK   E  KP+ PP   L +K++ LPLP+ LK YL
Sbjct: 85  CNQLILQPLDSEEDEEMEEDNKEEEEKDHSEAMKPEEPPQYLLTEKIMKLPLPESLKAYL 144

Query: 356 LYYREK 361
            Y+R+K
Sbjct: 145 TYFRDK 150


>gi|239745549 PREDICTED: hypothetical protein XP_002343514 [Homo
           sapiens]
          Length = 150

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 51/126 (40%), Positives = 75/126 (59%), Gaps = 8/126 (6%)

Query: 238 VAVRSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETIVFLDKEV 297
           + VR+LQDLA I IR T++  I+ E  +K G   +  P+ KR+RV++R     + +   V
Sbjct: 31  ITVRNLQDLALIYIRRTLRNFINDEMQAK-GIPQRAPPKRKRKRVKQR-----ITIYVCV 84

Query: 298 FASRISNPSDDNSCEDLEEERREEEEKTPPET-KPD-PPVNFLRQKVLSLPLPDPLKYYL 355
               I  P D    E++EE+ +EEEEK   E  KP+ PP   L +K++ LPLP+ LK YL
Sbjct: 85  CNQLILQPLDSEEDEEMEEDNKEEEEKDHSEAMKPEEPPQYLLTEKIMKLPLPESLKAYL 144

Query: 356 LYYREK 361
            Y+R+K
Sbjct: 145 TYFRDK 150


>gi|226530908 protein-L-isoaspartate (D-aspartate)
           O-methyltransferase 1 [Homo sapiens]
          Length = 285

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 58/226 (25%), Positives = 99/226 (43%), Gaps = 26/226 (11%)

Query: 6   SAGEDNDELIDNLKEAQYIRTELVEQAFRAIDRADYYLEEFKENAYKDLAWKHG-NIHLS 64
           S G  + ELI NL++   I+T+ V +   A DR+ Y     K N Y D     G    +S
Sbjct: 63  SGGASHSELIHNLRKNGIIKTDKVFEVMLATDRSHY----AKCNPYMDSPQSIGFQATIS 118

Query: 65  APCIYSEVMEAL--DLQPGLSFLNLGSGTGYLSS----MVGLILGPFGVNHGVELHSDVI 118
           AP +++  +E L   L  G   L++GSG+G L++    MVG      G++H  EL  D +
Sbjct: 119 APHMHAYALELLFDQLHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSV 178

Query: 119 EYAKQKLDFFIRTSDSFDKFDFCEPSFVTGNCLEISPDCSQYDRVYCGAGVQKEHEEYMK 178
              ++         D            V G+      + + YD ++ GA      +  + 
Sbjct: 179 NNVRK---------DDPTLLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALI- 228

Query: 179 NLLKVGGILVMPL-----EEKLTKITRTGPSAWETKKILAVSFAPL 219
           + LK GG L++P+      + L +  +    + + K ++ V + PL
Sbjct: 229 DQLKPGGRLILPVGPAGGNQMLEQYDKLQDGSIKMKPLMGVIYVPL 274


>gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]
          Length = 224

 Score = 37.7 bits (86), Expect = 0.016
 Identities = 20/55 (36%), Positives = 30/55 (54%), Gaps = 2/55 (3%)

Query: 299 ASRISNPSDDNSCEDLEEERREEEEKTPPETKPD--PPVNFLRQKVLSLPLPDPL 351
           +S +S P DD   E+ EEE  EEEE+   E + +  PP   + ++ L    PDP+
Sbjct: 35  SSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDPV 89


>gi|166197690 neuronal guanine nucleotide exchange factor isoform 2
           [Homo sapiens]
          Length = 618

 Score = 34.3 bits (77), Expect = 0.18
 Identities = 18/54 (33%), Positives = 30/54 (55%)

Query: 285 RRMETIVFLDKEVFASRISNPSDDNSCEDLEEERREEEEKTPPETKPDPPVNFL 338
           + +ET    D E+  +   +P+ +++ E+ EEE  EEE  +PPE K  P +  L
Sbjct: 97  QEIETRRQQDAEIEDNTNGSPASEDTPEEEEEEEEEEEPASPPERKTLPQICLL 150


>gi|166197688 neuronal guanine nucleotide exchange factor isoform 1
           [Homo sapiens]
          Length = 710

 Score = 34.3 bits (77), Expect = 0.18
 Identities = 18/54 (33%), Positives = 30/54 (55%)

Query: 285 RRMETIVFLDKEVFASRISNPSDDNSCEDLEEERREEEEKTPPETKPDPPVNFL 338
           + +ET    D E+  +   +P+ +++ E+ EEE  EEE  +PPE K  P +  L
Sbjct: 189 QEIETRRQQDAEIEDNTNGSPASEDTPEEEEEEEEEEEPASPPERKTLPQICLL 242


>gi|187761324 shootin1 isoform a [Homo sapiens]
          Length = 631

 Score = 33.5 bits (75), Expect = 0.30
 Identities = 26/127 (20%), Positives = 59/127 (46%), Gaps = 14/127 (11%)

Query: 240 VRSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETIVFLDKEVFA 299
           +++L + A++  +   ++I HQ+ V +    L+N    K     ++++E ++  DK+   
Sbjct: 263 LKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQLE-LLEEDKKELE 321

Query: 300 SRISNPSDD-----NSCEDLEEERREEEEKTPPETKPDPPVNFLRQKVLSLPLPDPLKYY 354
            +  N  +      +S ++L++   + E   PP   P PP        L  P P+P++  
Sbjct: 322 LKYQNSEEKARNLKHSVDELQKRVNQSENSVPPPPPPPPP--------LPPPPPNPIRSL 373

Query: 355 LLYYREK 361
           +   R++
Sbjct: 374 MSMIRKR 380


>gi|50511340 shootin1 isoform b [Homo sapiens]
          Length = 456

 Score = 33.5 bits (75), Expect = 0.30
 Identities = 26/127 (20%), Positives = 59/127 (46%), Gaps = 14/127 (11%)

Query: 240 VRSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETIVFLDKEVFA 299
           +++L + A++  +   ++I HQ+ V +    L+N    K     ++++E ++  DK+   
Sbjct: 263 LKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQLE-LLEEDKKELE 321

Query: 300 SRISNPSDD-----NSCEDLEEERREEEEKTPPETKPDPPVNFLRQKVLSLPLPDPLKYY 354
            +  N  +      +S ++L++   + E   PP   P PP        L  P P+P++  
Sbjct: 322 LKYQNSEEKARNLKHSVDELQKRVNQSENSVPPPPPPPPP--------LPPPPPNPIRSL 373

Query: 355 LLYYREK 361
           +   R++
Sbjct: 374 MSMIRKR 380


>gi|123173772 tRNA(m1A58)-methyltransferase subunit TRM61 [Homo
           sapiens]
          Length = 289

 Score = 32.0 bits (71), Expect = 0.88
 Identities = 16/49 (32%), Positives = 26/49 (53%)

Query: 76  LDLQPGLSFLNLGSGTGYLSSMVGLILGPFGVNHGVELHSDVIEYAKQK 124
           L+L+PG      G+G+G +S  +   + P G  H VE H    E A+++
Sbjct: 99  LELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREE 147


>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
           b [Homo sapiens]
          Length = 1524

 Score = 32.0 bits (71), Expect = 0.88
 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 12/86 (13%)

Query: 252 RGTIKKIIHQETVSKNGNG--LKNTPRFKRRRVRRRRMETIVFLDKEVFASRISNPSDDN 309
           R  +KKI+ +E + K      LK     +R ++R  + + + +L       + S P +D 
Sbjct: 349 REELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYL------KQWSKPREDM 402

Query: 310 SCEDLEEERREEEEKTPPETKPDPPV 335
            C+DL    +E  E TP +T+  P +
Sbjct: 403 ECDDL----KELPEPTPVKTRLPPEI 424


>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
           a [Homo sapiens]
          Length = 1556

 Score = 32.0 bits (71), Expect = 0.88
 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 12/86 (13%)

Query: 252 RGTIKKIIHQETVSKNGNG--LKNTPRFKRRRVRRRRMETIVFLDKEVFASRISNPSDDN 309
           R  +KKI+ +E + K      LK     +R ++R  + + + +L       + S P +D 
Sbjct: 349 REELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYL------KQWSKPREDM 402

Query: 310 SCEDLEEERREEEEKTPPETKPDPPV 335
            C+DL    +E  E TP +T+  P +
Sbjct: 403 ECDDL----KELPEPTPVKTRLPPEI 424


>gi|12056465 fibrillarin [Homo sapiens]
          Length = 321

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 4/56 (7%)

Query: 73  MEALDLQPGLSFLNLGSGTGYLSSMVGLILGPFGVNHGVELH----SDVIEYAKQK 124
           ++ + ++PG   L LG+ +G   S V  I+GP G+ + VE       D+I  AK++
Sbjct: 152 VDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKR 207


>gi|61966703 NHS-like 2 [Homo sapiens]
          Length = 709

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 16/33 (48%), Positives = 17/33 (51%)

Query: 303 SNPSDDNSCEDLEEERREEEEKTPPETKPDPPV 335
           S P DD    +  EE R EE  T PE K  PPV
Sbjct: 473 SEPEDDIESPEYAEEPRAEEVFTLPERKTKPPV 505


>gi|16507239 wingless-type MMTV integration site family, member 6
           precursor [Homo sapiens]
          Length = 365

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 7/53 (13%)

Query: 136 DKFDFCEPSFVTGN-------CLEISPDCSQYDRVYCGAGVQKEHEEYMKNLL 181
           D  DFC P+  TG+       C   +PD S  D + CG G ++E  +  +N L
Sbjct: 289 DSPDFCAPNRRTGSPGTRGRACNSSAPDLSGCDLLCCGRGHRQESVQLEENCL 341


>gi|83716024 kinesin family member 21B [Homo sapiens]
          Length = 1624

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 13/58 (22%)

Query: 276 RFKRRRVRRRRMETIVFLDKEVFASRI------SNPSDDNSCEDLEEERRE---EEEK 324
           R K++ VR+RR       +KE F  R       S  +D+N  E+ EEER E   EEE+
Sbjct: 550 RLKKKEVRQRRKSP----EKEAFKKRAKLQQENSEETDENEAEEEEEERDESGCEEEE 603


>gi|6912398 general transcription factor IIIC, polypeptide 3, 102kDa
           [Homo sapiens]
          Length = 886

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 16/37 (43%), Positives = 19/37 (51%)

Query: 296 EVFASRISNPSDDNSCEDLEEERREEEEKTPPETKPD 332
           +VFAS +    DD   E+ EEE  EEEE     T  D
Sbjct: 84  KVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGD 120


>gi|4759208 TAO kinase 2 isoform 1 [Homo sapiens]
          Length = 1049

 Score = 30.0 bits (66), Expect = 3.4
 Identities = 33/109 (30%), Positives = 45/109 (41%), Gaps = 14/109 (12%)

Query: 232 LVQLPPVAVRSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETIV 291
           L+Q    AVR L +L        +KKI+ QE  + NG G +     +       R  T+ 
Sbjct: 293 LIQRTKDAVRELDNLQY----RKMKKILFQE--APNGPGAEAPEEEEEAEPYMHRAGTLT 346

Query: 292 FLDKE-----VFASRISNPSDDNSCEDL---EEERREEEEKTPPETKPD 332
            L+       +  S  S  S  NS  D    EEE  EEEE+   E  P+
Sbjct: 347 SLESSHSVPSMSISASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPE 395


>gi|45505130 TAO kinase 2 isoform 2 [Homo sapiens]
          Length = 1235

 Score = 30.0 bits (66), Expect = 3.4
 Identities = 33/109 (30%), Positives = 45/109 (41%), Gaps = 14/109 (12%)

Query: 232 LVQLPPVAVRSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETIV 291
           L+Q    AVR L +L        +KKI+ QE  + NG G +     +       R  T+ 
Sbjct: 293 LIQRTKDAVRELDNLQY----RKMKKILFQE--APNGPGAEAPEEEEEAEPYMHRAGTLT 346

Query: 292 FLDKE-----VFASRISNPSDDNSCEDL---EEERREEEEKTPPETKPD 332
            L+       +  S  S  S  NS  D    EEE  EEEE+   E  P+
Sbjct: 347 SLESSHSVPSMSISASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPE 395


>gi|23346412 cysteine-serine-rich nuclear protein 3 [Homo sapiens]
          Length = 585

 Score = 29.6 bits (65), Expect = 4.4
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 5/65 (7%)

Query: 294 DKEVFASRISNPSDDN-----SCEDLEEERREEEEKTPPETKPDPPVNFLRQKVLSLPLP 348
           D   F S +++ S  +     S E+ EEE  EEEE+   + K D  V  L      +PLP
Sbjct: 348 DGSSFCSGVTDSSTQSLAPSESDEEEEEEEEEEEEEDDDDDKGDGFVEGLGTHAEVVPLP 407

Query: 349 DPLKY 353
             L Y
Sbjct: 408 SVLCY 412


>gi|68077166 DnaJ homology subfamily A member 5 isoform 2 [Homo
           sapiens]
          Length = 531

 Score = 29.6 bits (65), Expect = 4.4
 Identities = 19/74 (25%), Positives = 36/74 (48%), Gaps = 2/74 (2%)

Query: 266 KNGNGLKNTPRFKRRRVRRRRMETIVFLDKEVFASRI--SNPSDDNSCEDLEEERREEEE 323
           K    +KN  + K+ R     ++  +  ++E F+      NP DDNS E++E+  +++  
Sbjct: 324 KTEKAMKNHEKSKKHREMVALLKQQLEEEEENFSRPQIDENPLDDNSEEEMEDAPKQKLS 383

Query: 324 KTPPETKPDPPVNF 337
           K   + K  P  N+
Sbjct: 384 KKQKKKKQKPAQNY 397


>gi|5031703 Ras-GTPase-activating protein SH3-domain-binding protein
           [Homo sapiens]
          Length = 466

 Score = 29.6 bits (65), Expect = 4.4
 Identities = 17/57 (29%), Positives = 27/57 (47%), Gaps = 4/57 (7%)

Query: 296 EVFASRISNPSDDNSCEDLEEERREEEEKTPPETKPDPPVNFLRQKVLSLPLPDPLK 352
           EVF   ++ P +++     EE    EE +  PE  PD    F  Q V+S  + + L+
Sbjct: 136 EVFGGFVTEPQEESE----EEVEEPEERQQTPEVVPDDSGTFYDQAVVSNDMEEHLE 188


>gi|38327552 Ras-GTPase-activating protein SH3-domain-binding
           protein [Homo sapiens]
          Length = 466

 Score = 29.6 bits (65), Expect = 4.4
 Identities = 17/57 (29%), Positives = 27/57 (47%), Gaps = 4/57 (7%)

Query: 296 EVFASRISNPSDDNSCEDLEEERREEEEKTPPETKPDPPVNFLRQKVLSLPLPDPLK 352
           EVF   ++ P +++     EE    EE +  PE  PD    F  Q V+S  + + L+
Sbjct: 136 EVFGGFVTEPQEESE----EEVEEPEERQQTPEVVPDDSGTFYDQAVVSNDMEEHLE 188


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.137    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,074,425
Number of Sequences: 37866
Number of extensions: 729673
Number of successful extensions: 4271
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 4119
Number of HSP's gapped (non-prelim): 98
length of query: 361
length of database: 18,247,518
effective HSP length: 104
effective length of query: 257
effective length of database: 14,309,454
effective search space: 3677529678
effective search space used: 3677529678
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.