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Search of human proteins with 157388929
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157388929 epsin 3 [Homo sapiens]
(632 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157388929 epsin 3 [Homo sapiens] 1281 0.0
gi|194248095 epsin 1 isoform b [Homo sapiens] 446 e-125
gi|156671217 epsin 2 isoform a [Homo sapiens] 434 e-122
gi|41350201 epsin 1 isoform c [Homo sapiens] 415 e-116
gi|194272148 epsin 1 isoform a [Homo sapiens] 414 e-115
gi|156671215 epsin 2 isoform b [Homo sapiens] 406 e-113
gi|31377575 ENTH domain containing 1 [Homo sapiens] 210 4e-54
gi|7661968 epsin 4 [Homo sapiens] 172 1e-42
gi|156671219 epsin 2 isoform c [Homo sapiens] 108 1e-23
gi|163965366 nascent polypeptide-associated complex alpha subuni... 61 3e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 59 2e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 56 1e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 54 3e-07
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 54 6e-07
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi... 53 7e-07
gi|112421108 capicua homolog [Homo sapiens] 53 1e-06
gi|210032580 SET domain containing 1B [Homo sapiens] 52 1e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 52 2e-06
gi|150170670 piccolo isoform 2 [Homo sapiens] 52 2e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 52 2e-06
gi|116284392 mucin 2 precursor [Homo sapiens] 51 4e-06
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 49 1e-05
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 49 2e-05
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 47 4e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 46 1e-04
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 46 1e-04
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re... 46 1e-04
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 45 2e-04
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 45 2e-04
gi|223972704 hypothetical protein LOC284418 [Homo sapiens] 45 2e-04
>gi|157388929 epsin 3 [Homo sapiens]
Length = 632
Score = 1281 bits (3316), Expect = 0.0
Identities = 632/632 (100%), Positives = 632/632 (100%)
Query: 1 MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGML 60
MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGML
Sbjct: 1 MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGML 60
Query: 61 WRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQG 120
WRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQG
Sbjct: 61 WRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQG 120
Query: 121 VNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSRRYGEDYSRSR 180
VNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSRRYGEDYSRSR
Sbjct: 121 VNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSRRYGEDYSRSR 180
Query: 181 GSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPASHRDEDLQ 240
GSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPASHRDEDLQ
Sbjct: 181 GSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPASHRDEDLQ 240
Query: 241 LQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQSSI 300
LQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQSSI
Sbjct: 241 LQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQSSI 300
Query: 301 LDLADIFVPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQP 360
LDLADIFVPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQP
Sbjct: 301 LDLADIFVPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQP 360
Query: 361 WDLTPMLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGAS 420
WDLTPMLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGAS
Sbjct: 361 WDLTPMLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGAS 420
Query: 421 TFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILG 480
TFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILG
Sbjct: 421 TFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILG 480
Query: 481 EALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFG 540
EALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFG
Sbjct: 481 EALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFG 540
Query: 541 AGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFP 600
AGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFP
Sbjct: 541 AGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFP 600
Query: 601 QAGAFAPQPLLPTPSSAGPRPPPPQTGTNPFL 632
QAGAFAPQPLLPTPSSAGPRPPPPQTGTNPFL
Sbjct: 601 QAGAFAPQPLLPTPSSAGPRPPPPQTGTNPFL 632
>gi|194248095 epsin 1 isoform b [Homo sapiens]
Length = 576
Score = 446 bits (1148), Expect = e-125
Identities = 300/672 (44%), Positives = 370/672 (55%), Gaps = 137/672 (20%)
Query: 1 MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGML 60
M+TS+LRRQ+KNIVHNYSEAEIKVREATSNDPWGP SSLMSEIADLT+N VAF+E+M M+
Sbjct: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60
Query: 61 WRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQG 120
W+RLND GKNWRHVYKA+TL++YL+KTGSERV+ QC+EN+Y +QTLKDFQY+DRDGKDQG
Sbjct: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120
Query: 121 VNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSRRYGEDYSRSR 180
VNVREK KQ++ALL+DE+RLR+ER HALKTKE++A
Sbjct: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLA-----------------------QT 157
Query: 181 GSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPASHRDEDLQ 240
+ SS S P + EQA PQ+SGEEELQLQLALAMS+EEA++ PP+ ++D Q
Sbjct: 158 ATASSAAVGSGPP---PEAEQAWPQSSGEEELQLQLALAMSKEEADQ--PPSCGPEDDAQ 212
Query: 241 LQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQSSI 300
LQLAL LSR+EH+KE R +GD + E +RE +EE SS+
Sbjct: 213 LQLALSLSREEHDKEERIRRGDDLRL---------QMAIEESKRETGGKEE------SSL 257
Query: 301 LDLADIFVPALAPPSTHCSADPWDIP----GFRPNTEASGSSWG-----PSADPW-SPIP 350
+DLAD+F P+T DPW P P + WG P+ADPW P P
Sbjct: 258 MDLADVFTAPAPAPTT----DPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAP 313
Query: 351 SGTVLSRSQPW-DLTPMLSSSEPWGRTPVLPAGP-PTTDPWA-------LNSPHHKLPST 401
+ + PW P S +PWG TP AG PT DPW ++ P P T
Sbjct: 314 TP---ASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWT 370
Query: 402 GA----DPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFG 457
A DPWG S T G + F P+ + L ALP+ SS EL+L
Sbjct: 371 PAPAFSDPWGGSPAKPST-NGTTAAGGFDTEPDEFSDFDRLRTALPT-SGSSAGELELLA 428
Query: 458 DPSPSSKQNGTKEPDALDL----GILGEALTQPSKEARAC------RTPESFLGPSASSL 507
P+ + P A D+ G L EA+ P A +TPESFLGP+A +L
Sbjct: 429 GEVPA------RSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNA-AL 481
Query: 508 VNLDSLVK----APQVAKTRNPFLTG---LSAPSPTNPFGAGEPGRPTLNQMRTGSPALG 560
V+LDSLV P AK NPFL G + PS TNPF P TLNQ+R SP
Sbjct: 482 VDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRL-SPVPP 540
Query: 561 LAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPR 620
+ G P P +S + G LP P++P
Sbjct: 541 VPGAP--------------PTYISPLGGGPGLP---------------PMMP-------- 563
Query: 621 PPPPQTGTNPFL 632
P PP TNPFL
Sbjct: 564 PGPPAPNTNPFL 575
>gi|156671217 epsin 2 isoform a [Homo sapiens]
Length = 584
Score = 434 bits (1117), Expect = e-122
Identities = 295/659 (44%), Positives = 378/659 (57%), Gaps = 103/659 (15%)
Query: 1 MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGML 60
MTTS++RRQ+KNIV+NYSEAEIKVREATSNDPWGP SSLM+EIADLT+N VAF+E+M M+
Sbjct: 1 MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMV 60
Query: 61 WRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQG 120
W+RLND GKNWRHVYKALTLLDYL+KTGSERVA QCREN++ IQTLKDFQYIDRDGKDQG
Sbjct: 61 WKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQG 120
Query: 121 VNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSR---------- 170
+NVREK KQ++ALLKDEERL+ ER ALKTKERMA G+GS Q+ F R
Sbjct: 121 INVREKSKQLVALLKDEERLKAERAQALKTKERMAQVATGMGSNQITFGRGSSQPNLSTS 180
Query: 171 RYGEDYSRSRGSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVP 230
++Y ++ GSP+SY+ S+SPR +S+LEQARPQTSGEEELQLQLALAMSRE AE+
Sbjct: 181 HSEQEYGKAGGSPASYH-GSTSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQ--E 237
Query: 231 PASHRDEDLQLQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEE 290
R +DL+LQ+AL SR R+ + +K+E
Sbjct: 238 ERLRRGDDLRLQMALEESR------------------------------RDTVKIPKKKE 267
Query: 291 EKLKTSQSSILDLADIFVPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIP 350
Q+++LDL D +P+ P + A+PW AS + P P +P
Sbjct: 268 HGSLPQQTTLLDLMDA-LPSSGPAAQ--KAEPW-------GPSASTNQTNPWGGPAAP-- 315
Query: 351 SGTVLSRSQPWDL--TPMLSSSEPWGRTPVLPAG------PPTTDPWALN-SPHHKLPST 401
S S PW T +S +PWG +P G P +DPWA + P
Sbjct: 316 ----ASTSDPWPSFGTKPAASIDPWG----VPTGATVQSVPKNSDPWAASQQPASSAGKR 367
Query: 402 GADPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSP 461
+D WGA + T+ + +F+ F+ + + L + K ++ L
Sbjct: 368 ASDAWGA-VSTTKPVSVSGSFELFSNLNGTIKDDFSEFDNLRTSKKTAESVTSL------ 420
Query: 462 SSKQNGTKEPDALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAP-QVA 520
S+ NGT PD + L A ++PS A +TPESFLGP+A +LVNLDSLV P A
Sbjct: 421 PSQNNGTTSPDPFESQPLTVASSKPSS---ARKTPESFLGPNA-ALVNLDSLVTRPAPPA 476
Query: 521 KTRNPFLT-GLSAPS-PTNPFGAGEPGRPTLNQMRTGSPALG----LAGGPVGAPLGSMT 574
++ NPFL G A S P NPF +P TLNQ+R GSP LG GP + +
Sbjct: 477 QSLNPFLAPGAPATSAPVNPFQVNQPQPLTLNQLR-GSPVLGTSTSFGPGPGVESMAVAS 535
Query: 575 YSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPRPPPPQTG-TNPFL 632
+++ P P P ++ G+ +P PS+A TG TNPFL
Sbjct: 536 MTSAAPQPALGATGSSLTPLGPAMMNMVGSVG----IP-PSAA------QATGTTNPFL 583
>gi|41350201 epsin 1 isoform c [Homo sapiens]
Length = 550
Score = 415 bits (1066), Expect = e-116
Identities = 288/672 (42%), Positives = 355/672 (52%), Gaps = 163/672 (24%)
Query: 1 MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGML 60
M+TS+LRRQ+KNIVHNYSEAEIKVREATSNDPWGP SSLMSEIADLT+N VAF+E+M M+
Sbjct: 1 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 60
Query: 61 WRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQG 120
W+RLND GKNWRHVYKA+TL++YL+KTGSERV+ QC+EN+Y +QTLKDFQY+DRDGKDQG
Sbjct: 61 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 120
Query: 121 VNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSRRYGEDYSRSR 180
VNVREK KQ++ALL+DE+RLR+ER HALKTKE++A
Sbjct: 121 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLA-----------------------QT 157
Query: 181 GSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPASHRDEDLQ 240
+ SS S P + EQA PQ+SGEEELQLQLALAMS+EEA++ R +DL+
Sbjct: 158 ATASSAAVGSGPP---PEAEQAWPQSSGEEELQLQLALAMSKEEADQ--EERIRRGDDLR 212
Query: 241 LQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQSSI 300
LQ+A+ E +RE +EE SS+
Sbjct: 213 LQMAI----------------------------------EESKRETGGKEE------SSL 232
Query: 301 LDLADIFVPALAPPSTHCSADPWDIP----GFRPNTEASGSSWG-----PSADPW-SPIP 350
+DLAD+F P+T DPW P P + WG P+ADPW P P
Sbjct: 233 MDLADVFTAPAPAPTT----DPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAP 288
Query: 351 SGTVLSRSQPW-DLTPMLSSSEPWGRTPVLPAGP-PTTDPWA-------LNSPHHKLPST 401
+ + PW P S +PWG TP AG PT DPW ++ P P T
Sbjct: 289 TP---ASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWT 345
Query: 402 GA----DPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFG 457
A DPWG S T G +T F P+ + L ALP+ SS EL+L
Sbjct: 346 PAPAFSDPWGGSPAKPSTNG--TTAGGFDTEPDEFSDFDRLRTALPT-SGSSAGELELLA 402
Query: 458 DPSPSSKQNGTKEPDALDL----GILGEALTQPSKEARAC------RTPESFLGPSASSL 507
P+ + P A D+ G L EA+ P A +TPESFLGP+A +L
Sbjct: 403 GEVPA------RSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNA-AL 455
Query: 508 VNLDSLVK----APQVAKTRNPFLTG---LSAPSPTNPFGAGEPGRPTLNQMRTGSPALG 560
V+LDSLV P AK NPFL G + PS TNPF P TLNQ+R SP
Sbjct: 456 VDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRL-SPVPP 514
Query: 561 LAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPR 620
+ G P P +S + G LP P++P
Sbjct: 515 VPGAP--------------PTYISPLGGGPGLP---------------PMMP-------- 537
Query: 621 PPPPQTGTNPFL 632
P PP TNPFL
Sbjct: 538 PGPPAPNTNPFL 549
>gi|194272148 epsin 1 isoform a [Homo sapiens]
Length = 662
Score = 414 bits (1064), Expect = e-115
Identities = 287/672 (42%), Positives = 354/672 (52%), Gaps = 162/672 (24%)
Query: 1 MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGML 60
M+TS+LRRQ+KNIVHNYSEAEIKVREATSNDPWGP SSLMSEIADLT+N VAF+E+M M+
Sbjct: 112 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMI 171
Query: 61 WRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQG 120
W+RLND GKNWRHVYKA+TL++YL+KTGSERV+ QC+EN+Y +QTLKDFQY+DRDGKDQG
Sbjct: 172 WKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQG 231
Query: 121 VNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSRRYGEDYSRSR 180
VNVREK KQ++ALL+DE+RLR+ER HALKTKE++A
Sbjct: 232 VNVREKAKQLVALLRDEDRLREERAHALKTKEKLA-----------------------QT 268
Query: 181 GSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPASHRDEDLQ 240
+ SS S P + EQA PQ+SGEEELQLQLALAMS+EEA++ R +DL+
Sbjct: 269 ATASSAAVGSGPP---PEAEQAWPQSSGEEELQLQLALAMSKEEADQ--EERIRRGDDLR 323
Query: 241 LQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQSSI 300
LQ+A+ E +RE +EE SS+
Sbjct: 324 LQMAI----------------------------------EESKRETGGKEE------SSL 343
Query: 301 LDLADIFVPALAPPSTHCSADPWDIP----GFRPNTEASGSSWG-----PSADPW-SPIP 350
+DLAD+F P+T DPW P P + WG P+ADPW P P
Sbjct: 344 MDLADVFTAPAPAPTT----DPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAP 399
Query: 351 SGTVLSRSQPW-DLTPMLSSSEPWGRTPVLPAGP-PTTDPWA-------LNSPHHKLPST 401
+ + PW P S +PWG TP AG PT DPW ++ P P T
Sbjct: 400 TP---ASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWT 456
Query: 402 GA----DPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFG 457
A DPWG S T G + F P+ + L ALP+ SS EL+L
Sbjct: 457 PAPAFSDPWGGSPAKPST-NGTTAAGGFDTEPDEFSDFDRLRTALPT-SGSSAGELELLA 514
Query: 458 DPSPSSKQNGTKEPDALDL----GILGEALTQPSKEARAC------RTPESFLGPSASSL 507
P+ + P A D+ G L EA+ P A +TPESFLGP+A +L
Sbjct: 515 GEVPA------RSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNA-AL 567
Query: 508 VNLDSLVK----APQVAKTRNPFLTG---LSAPSPTNPFGAGEPGRPTLNQMRTGSPALG 560
V+LDSLV P AK NPFL G + PS TNPF P TLNQ+R SP
Sbjct: 568 VDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRL-SPVPP 626
Query: 561 LAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPR 620
+ G P P +S + G LP P++P
Sbjct: 627 VPGAP--------------PTYISPLGGGPGLP---------------PMMP-------- 649
Query: 621 PPPPQTGTNPFL 632
P PP TNPFL
Sbjct: 650 PGPPAPNTNPFL 661
>gi|156671215 epsin 2 isoform b [Homo sapiens]
Length = 641
Score = 406 bits (1044), Expect = e-113
Identities = 295/715 (41%), Positives = 375/715 (52%), Gaps = 158/715 (22%)
Query: 1 MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGML 60
MTTS++RRQ+KNIV+NYSEAEIKVREATSNDPWGP SSLM+EIADLT+N VAF+E+M M+
Sbjct: 1 MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMV 60
Query: 61 WRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQG 120
W+RLND GKNWRHVYKALTLLDYL+KTGSERVA QCREN++ IQTLKDFQYIDRDGKDQG
Sbjct: 61 WKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQG 120
Query: 121 VNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSR---------- 170
+NVREK KQ++ALLKDEERL+ ER ALKTKERMA G+GS Q+ F R
Sbjct: 121 INVREKSKQLVALLKDEERLKAERAQALKTKERMAQVATGMGSNQITFGRGSSQPNLSTS 180
Query: 171 RYGEDYSRSRGSPSSYNSSS---------------------------------------- 190
++Y ++ GSP+SY+ S
Sbjct: 181 HSEQEYGKAGGSPASYHGSPEASLCPQHRTGAPLGQSEELQPLSQRHPFLPHLGLASRPN 240
Query: 191 ---SSPRYTSD-------------LEQARPQTSGEEELQLQLALAMSREEAEKPVPPASH 234
S P T D LEQARPQTSGEEELQLQLALAMSRE AE+
Sbjct: 241 GDWSQPCLTCDRAARATSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQ--EERLR 298
Query: 235 RDEDLQLQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLK 294
R +DL+LQ+AL SR R+ + +K+E
Sbjct: 299 RGDDLRLQMALEESR------------------------------RDTVKIPKKKEHGSL 328
Query: 295 TSQSSILDLADIFVPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTV 354
Q+++LDL D +P+ P + A+PW AS + P P +P
Sbjct: 329 PQQTTLLDLMDA-LPSSGPAAQ--KAEPW-------GPSASTNQTNPWGGPAAP------ 372
Query: 355 LSRSQPWDL--TPMLSSSEPWGRTPVLPAG------PPTTDPWALN-SPHHKLPSTGADP 405
S S PW T +S +PWG +P G P +DPWA + P +D
Sbjct: 373 ASTSDPWPSFGTKPAASIDPWG----VPTGATVQSVPKNSDPWAASQQPASSAGKRASDA 428
Query: 406 WGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQ 465
WGA + T+ + +F+ F+ + + L + K ++ L S+
Sbjct: 429 WGA-VSTTKPVSVSGSFELFSNLNGTIKDDFSEFDNLRTSKKTAESVTSL------PSQN 481
Query: 466 NGTKEPDALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAP-QVAKTRN 524
NGT PD + L A ++PS A +TPESFLGP+A +LVNLDSLV P A++ N
Sbjct: 482 NGTTSPDPFESQPLTVASSKPSS---ARKTPESFLGPNA-ALVNLDSLVTRPAPPAQSLN 537
Query: 525 PFLT-GLSAPS-PTNPFGAGEPGRPTLNQMRTGSPALG----LAGGPVGAPLGSMTYSAS 578
PFL G A S P NPF +P TLNQ+R GSP LG GP + + +++
Sbjct: 538 PFLAPGAPATSAPVNPFQVNQPQPLTLNQLR-GSPVLGTSTSFGPGPGVESMAVASMTSA 596
Query: 579 LPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPRPPPPQTG-TNPFL 632
P P P ++ G+ +P PS+A TG TNPFL
Sbjct: 597 APQPALGATGSSLTPLGPAMMNMVGSVG----IP-PSAA------QATGTTNPFL 640
>gi|31377575 ENTH domain containing 1 [Homo sapiens]
Length = 607
Score = 210 bits (534), Expect = 4e-54
Identities = 104/165 (63%), Positives = 125/165 (75%), Gaps = 1/165 (0%)
Query: 5 ALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGMLWRRL 64
A RRQVKN V NYS+AEIKVREATSNDPWGP SSLM +I+DLTFNT++ +E+M MLW RL
Sbjct: 2 AFRRQVKNFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTISLSEIMNMLWHRL 61
Query: 65 NDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVR 124
ND GKNWRHVYK+LTL+DYL+K GS++V CRE +QTLKDFQ+ID GKDQG +R
Sbjct: 62 NDHGKNWRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQTLKDFQHIDEAGKDQGYYIR 121
Query: 125 EKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFS 169
EK KQV+ LL DE L +ER A +T++R + I QLG S
Sbjct: 122 EKSKQVITLLMDEPLLCKEREVACRTRQRTS-HSILFSKRQLGSS 165
>gi|7661968 epsin 4 [Homo sapiens]
Length = 625
Score = 172 bits (435), Expect = 1e-42
Identities = 159/606 (26%), Positives = 261/606 (43%), Gaps = 81/606 (13%)
Query: 12 NIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGMLWRR-LNDSGKN 70
N+V NYSE E KVREAT++DPWGP LM EIA TF F E+M MLW R L D+ KN
Sbjct: 16 NVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKN 75
Query: 71 WRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQV 130
WR VYK+L LL YL++ GSERV RE++Y +++L+++ ++D GKDQG+N+R+KVK++
Sbjct: 76 WRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKEL 135
Query: 131 MALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSRRYGEDYSRSRGS--PSSYNS 188
+ +D++RLR+ER A K K++ +G+ S +G RY E Y S ++
Sbjct: 136 VEFAQDDDRLREERKKAKKNKDKY----VGVSSDSVG-GFRYSERYDPEPKSKWDEEWDK 190
Query: 189 SSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPASHRDEDLQLQLALRLS 248
+ S+ ++ L + + + + RE++ + R S
Sbjct: 191 NKSAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPE------------------RCS 232
Query: 249 RQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQSSILDLADIFV 308
+ EK+ R R R P+ E + EEE + T I +
Sbjct: 233 DSDEEKKAR--------------------RGRSPKGEFKDEEETVTTKHIHITQATETTT 272
Query: 309 P----ALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLT 364
P T G + + + + S+ P + + +PS DL
Sbjct: 273 TRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSS-----KSSGDLV 327
Query: 365 PML-SSSEPWGRTPVLPAGPPTTDPWALNS--PHHKLPSTGADPWGASLETSDTPGG--A 419
+ +S+ G + L G A + P ++G +G + P G A
Sbjct: 328 DLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVA 387
Query: 420 STFDPFAKPPE-STETKEGLEQAL--PSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDL 476
S+ + F + + E G + AL P +S DL G + + + +
Sbjct: 388 SSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMST 447
Query: 477 GILGEAL-------TQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTG 529
+G L T +++ + P ++ PS + ++LD+L+ Q +K + P L
Sbjct: 448 NTVGLGLPMSRSQNTDMVQKSVSKTLPSTWSDPSVN--ISLDNLLPGMQPSKPQQPSLNT 505
Query: 530 L----SAPSP----TNPFGAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPL 581
+ + P T FGA P+ N + L GGP+ + ++
Sbjct: 506 MIQQQNMQQPMNVMTQSFGAVNLSSPS-NMLPVRPQTNALIGGPMPMSMPNVMTGTMGMA 564
Query: 582 PLSSVP 587
PL + P
Sbjct: 565 PLGNTP 570
>gi|156671219 epsin 2 isoform c [Homo sapiens]
Length = 356
Score = 108 bits (270), Expect = 1e-23
Identities = 129/430 (30%), Positives = 184/430 (42%), Gaps = 92/430 (21%)
Query: 220 MSREEAEKPVPPASHRDEDLQLQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRD 279
MSRE AE+ R +DL+LQ+AL SR
Sbjct: 1 MSREVAEQE--ERLRRGDDLRLQMALEESR------------------------------ 28
Query: 280 REPEREERKEEEKLKTSQSSILDLADIFVPALAPPSTHCSADPWDIPGFRPNTEASGSSW 339
R+ + +K+E Q+++LDL D +P+ P + A+PW AS +
Sbjct: 29 RDTVKIPKKKEHGSLPQQTTLLDLMDA-LPSSGPAAQ--KAEPW-------GPSASTNQT 78
Query: 340 GPSADPWSPIPSGTVLSRSQPWDL--TPMLSSSEPWGRTPVLPAG------PPTTDPWAL 391
P P +P S S PW T +S +PWG +P G P +DPWA
Sbjct: 79 NPWGGPAAPA------STSDPWPSFGTKPAASIDPWG----VPTGATVQSVPKNSDPWAA 128
Query: 392 NS-PHHKLPSTGADPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSP 450
+ P +D WGA + T+ + +F+ F+ + + L + K ++
Sbjct: 129 SQQPASSAGKRASDAWGA-VSTTKPVSVSGSFELFSNLNGTIKDDFSEFDNLRTSKKTAE 187
Query: 451 VELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNL 510
L S+ NGT PD + L A ++PS A +TPESFLGP+A +LVNL
Sbjct: 188 SVTSL------PSQNNGTTSPDPFESQPLTVASSKPSS---ARKTPESFLGPNA-ALVNL 237
Query: 511 DSLVKAP-QVAKTRNPFLT-GLSAPS-PTNPFGAGEPGRPTLNQMRTGSPALG----LAG 563
DSLV P A++ NPFL G A S P NPF +P TLNQ+R GSP LG
Sbjct: 238 DSLVTRPAPPAQSLNPFLAPGAPATSAPVNPFQVNQPQPLTLNQLR-GSPVLGTSTSFGP 296
Query: 564 GPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPRPPP 623
GP + + +++ P P P ++ G+ +P PS+A
Sbjct: 297 GPGVESMAVASMTSAAPQPALGATGSSLTPLGPAMMNMVGSVG----IP-PSAA------ 345
Query: 624 PQTG-TNPFL 632
TG TNPFL
Sbjct: 346 QATGTTNPFL 355
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 61.2 bits (147), Expect = 3e-09
Identities = 89/336 (26%), Positives = 114/336 (33%), Gaps = 49/336 (14%)
Query: 309 PALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSP--IPSGTVLSRSQPWDLTPM 366
PA+ PPS S P G+S P+A P SP P+ T L + P
Sbjct: 1012 PAVTPPSPKGSPAATPFP--------KGASTPPAATPPSPKGSPAATPLPKGAPTTPAAT 1063
Query: 367 LSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTP----GGAST- 421
L S + TP L P P A P K P GA + + TP GG +T
Sbjct: 1064 LPSPKGGPATPSLKGAPT---PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120
Query: 422 ------FDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALD 475
P A PP K GL P G P++P +P S + G P
Sbjct: 1121 PHKGAPTTPAATPPSP---KGGLATPPPKGAPTTPAA-------TPPSPKGGLATPPPKG 1170
Query: 476 LGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSP 535
A K A +P+ A++ + + P P + PSP
Sbjct: 1171 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA--PTTPAATPPSP 1228
Query: 536 TNPFGAGEP-GRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPA 594
P G PT SP G A P P G+ T A+ P S+ GL P
Sbjct: 1229 KGGLATPSPKGAPTTPAATPPSPKGGPATPP---PKGAPTPPAATP---PSLKGGLATP- 1281
Query: 595 SVSVFPQAGAFAPQPLLPTPSSAGPRPPPPQTGTNP 630
P GA P + P GP PP+ P
Sbjct: 1282 -----PHKGAPNPAVVTPPSPKGGPATSPPKGAPTP 1312
Score = 50.1 bits (118), Expect = 6e-06
Identities = 78/312 (25%), Positives = 107/312 (34%), Gaps = 35/312 (11%)
Query: 331 NTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTTDPW- 389
++ A+ S P + +P PS + L P + + P GP T P
Sbjct: 848 DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907
Query: 390 --ALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKP 447
AL+ A P + S +P GA T P A PP K G P P
Sbjct: 908 APALSMTSSSPKKARATPAPKGIPASPSPKGAPT-PPAATPPSP---KGGPATPSPKWAP 963
Query: 448 SSPVELDLF--GDPSPSSKQNGTKEPDALDLGILGEALTQPSKEARACRTPESFLGPSAS 505
+ P G P+ S + P A G T K A TP + PS
Sbjct: 964 TPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAP---TPPAVTPPS-- 1018
Query: 506 SLVNLDSLVKAPQVAKTRNPFLTGLSAP-SPTNPFGAGEPGRPTLNQMRTGSPALGLA-- 562
P+ + PF G S P + T P G P L + +PA L
Sbjct: 1019 -----------PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067
Query: 563 -GGPVGAPL-GSMTYSASLPL-----PLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPS 615
GGP L G+ T A+ P P + P G +P + + G A P P+
Sbjct: 1068 KGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPT 1127
Query: 616 SAGPRPPPPQTG 627
+ PP P+ G
Sbjct: 1128 TPAATPPSPKGG 1139
Score = 48.5 bits (114), Expect = 2e-05
Identities = 92/365 (25%), Positives = 120/365 (32%), Gaps = 58/365 (15%)
Query: 309 PALAPPST-------HCSA------DPWDIPGFRPNTEASGSSWGPS---ADPWSPIPSG 352
PA PP T H SA P + P A+ SS G AD SP P G
Sbjct: 741 PAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLAD--SPSPLG 798
Query: 353 TVLSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKL--------PSTGAD 404
+S P P TP+ P + A P + L P+T
Sbjct: 799 VSVS---PQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHS 855
Query: 405 PWGASLETSDTPGGASTFDP--FAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSPS 462
P S + + TP + P PP+ T T + P P++P P+ S
Sbjct: 856 PTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQA---PALS 912
Query: 463 SKQNGTKEPDALDL--GILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVA 520
+ K+ A GI + + A P GP+ S P A
Sbjct: 913 MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPS----PKWAPTPPAA 968
Query: 521 KTRNPFLTGLSAPSP---------TNPFGAGEP------GRPTLNQMRTGSPALGLAGGP 565
+P G + PSP T P G P G PT + SP A P
Sbjct: 969 TPPSP-KGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATP 1027
Query: 566 VGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPRPPPPQ 625
P G+ T A+ P PA LP P A +P+ TPS G PP
Sbjct: 1028 F--PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA 1085
Query: 626 TGTNP 630
T +P
Sbjct: 1086 TPPSP 1090
Score = 46.6 bits (109), Expect = 7e-05
Identities = 91/385 (23%), Positives = 129/385 (33%), Gaps = 87/385 (22%)
Query: 309 PALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPMLS 368
PA PPS G G+ P+A P SP G + TP +
Sbjct: 1198 PAATPPSPK---------GGLATPSPKGAPTTPAATPPSP-KGGLATPSPKGAPTTPAAT 1247
Query: 369 SSEPWGR--------TPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGAS 420
P G P PA P + L +P HK GA ++ T +P G
Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK----GAP--NPAVVTPPSPKGG- 1300
Query: 421 TFDPFAKPPESTETKEGLEQALPSGKPSSP------------------------VELDLF 456
P PP+ T P G P +P
Sbjct: 1301 ---PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK 1357
Query: 457 GDPSPSSKQNGTKEPDALDLGILGEALTQPS-KEARACRTPESFLGPSASSLVNLDSLVK 515
G P+ S + G P A G A+T PS K A +P+ P++ +++ L S K
Sbjct: 1358 GGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKG--DPTSPAVIPL-SPKK 1414
Query: 516 APQVAKTRN------------PFLTGLS---APSPTNPFGA----GEPGRPTLNQMRTGS 556
AP TR P +T +S AP+ + P G G PTL + S
Sbjct: 1415 APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPS 1474
Query: 557 PALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLP---- 612
P A V A S + + P P+ + +P+S P + P+ P
Sbjct: 1475 PKEPPAPKQV-ATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATL 1533
Query: 613 ----TPSSAGPRP---PPPQTGTNP 630
TP++ P+ PP T +P
Sbjct: 1534 LSKKTPATLAPKEALIPPAMTVPSP 1558
Score = 45.4 bits (106), Expect = 2e-04
Identities = 94/357 (26%), Positives = 132/357 (36%), Gaps = 64/357 (17%)
Query: 309 PALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSP-----IPSGTVLSRSQPWDL 363
PA PPS P PG P G+ P+ P SP +P+ T S+ P
Sbjct: 1313 PAATPPS------PKGSPGTPP---PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP--T 1361
Query: 364 TPMLSSSE---PWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASL------ETSD 414
TP SS E P TP GP T P P +PS DP ++ +
Sbjct: 1362 TP--SSKEGPTPPAATPSHKGGPAMTPPSPKRGP--AIPSPKGDPTSPAVIPLSPKKAPA 1417
Query: 415 TP----GGASTFDPFAKPPESTET--KEGLEQALPSGKPSSPVELDLFGDPS-PSSKQNG 467
TP G A+ PP T K+ + P G P++P GDP+ P+
Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSK---GDPTLPAVTPPS 1474
Query: 468 TKEPDALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRN--- 524
KEP A + + S +A TP P+ +++ S + P +R
Sbjct: 1475 PKEPPA------PKQVATSSSPKKAPATPAPMGAPTLPAVIP-SSPKEVPATPSSRRDPI 1527
Query: 525 -PFLTGLSAPSPTN--PFGAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPL 581
P T LS +P P A P T+ + +PA+ P AP + AS P
Sbjct: 1528 APTATLLSKKTPATLAPKEALIPPAMTVPSPKK-TPAIPT---PKEAPATPSSKEASSPP 1583
Query: 582 PLSSV-------PAGLTLPASV-SVFPQAGAFAPQPLLPTPSSAGPRPPPPQTGTNP 630
++ P L +P +V S P+ P P+P P P T T+P
Sbjct: 1584 AVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP 1640
Score = 39.7 bits (91), Expect = 0.009
Identities = 54/198 (27%), Positives = 82/198 (41%), Gaps = 28/198 (14%)
Query: 429 PESTETKEGLEQALPSGKPSSPVELDLFGDPSPS-SKQNGTKEPDALDLGILGEALTQPS 487
PE+T K+ L + LP GKP+S + L + S S K + PD+ +L +L P+
Sbjct: 586 PEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAG-PLLKSSLITPT 644
Query: 488 KEARACRTPESFLGPSASSLVNLDSLVKAPQVAK-------TRNPFLTGLSAPSPTNPFG 540
+A L + D AP AK T +PFL G + +P N
Sbjct: 645 --------------VAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKN-HP 689
Query: 541 AGEPGRPTLNQMRTGSPALGLAGGPVG--APLGSMTYSASLP--LPLSSVPAGLTLPASV 596
E TL + T S +A P APL ++ + +P +P S+P T P +
Sbjct: 690 VKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTK 749
Query: 597 SVFPQAGAFAPQPLLPTP 614
V + A P+ +P
Sbjct: 750 KVDGISHTSALAPVASSP 767
Score = 36.2 bits (82), Expect = 0.094
Identities = 58/221 (26%), Positives = 78/221 (35%), Gaps = 25/221 (11%)
Query: 428 PPESTETKEGLEQALPSGKPSSPV--------ELDLFGDPSPSSKQNGTKEPDALDLGIL 479
P E+TET EQ LP + + V G P P+ + P L
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
Query: 480 GEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPF 539
+A PS A TP P +SS L L AP+ FL L P P +P
Sbjct: 62 NQASPFPSPSTIA-STPLEVPFPQSSSGTAL-PLGTAPEAP----TFLPNLIGP-PISP- 113
Query: 540 GAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVF 599
A P + G+P+ V S+ S++ P L + P + + S SV
Sbjct: 114 AALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVI 173
Query: 600 PQAGAFAPQP----LLPTPSSAGPRP-----PPPQTGTNPF 631
+ AP L PS P P PP T P+
Sbjct: 174 TLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPY 214
Score = 31.2 bits (69), Expect = 3.0
Identities = 69/311 (22%), Positives = 111/311 (35%), Gaps = 76/311 (24%)
Query: 338 SWGPSADPWSPIPSGTVLSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTTDPWALNSPHHK 397
S GP ++ P+ V++ P + + +++ T +P PP DP L +
Sbjct: 468 SSGPISNIEPTSPAALVMAPVAPKEPSTQVAT------TLRIPVSPPLPDPEDLKN---- 517
Query: 398 LPSTGADPWGASLETSDTPGGASTFDPFAKPPESTETKEG-----LEQALPSGKPS---- 448
LPS+ + + P PF+ TK+ L QA P PS
Sbjct: 518 LPSSVLVKFPTQKDLQTVPASLEGA-PFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQST 576
Query: 449 -SPVELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQP---SKEARACRTPESFLGPSA 504
S E+ L + + + K G + L +G ++T P + A +T +S+ GP +
Sbjct: 577 SSSPEIPLSPEATLAKKSLG----EPLPIGKPASSMTSPLGVNSSASVIKT-DSYAGPDS 631
Query: 505 SSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGRPTLNQMRTGSPALGLAGG 564
+ + SL+ P VA P + +P AG
Sbjct: 632 AGPLLKSSLI-TPTVAAF---------------PLESADP-----------------AGV 658
Query: 565 PVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQ-----AGAFAPQPLLPTPSSAGP 619
G+ TY+ + A L +VS+ P+ G PL+PT S P
Sbjct: 659 APTTAKGTSTYTTT---------ASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCP 709
Query: 620 RPPPPQTGTNP 630
P PQ P
Sbjct: 710 VAPSPQNTCAP 720
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 58.5 bits (140), Expect = 2e-08
Identities = 94/375 (25%), Positives = 135/375 (36%), Gaps = 60/375 (16%)
Query: 264 SPMANGAGAVVHHQRDREPEREERKEEEKLKTSQSSILDLADIFVPALAPPSTHCSADPW 323
SP +G A + P + + K + L+ Q + PAL P S+
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ--VTPPRKDAAPALGPLSSS------ 302
Query: 324 DIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPMLSSSEPWGRT-PVLPAG 382
P P+ A+ S P P +P S + P L P S+ P +T P PA
Sbjct: 303 --PLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360
Query: 383 PPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKPPESTETKEGLE--Q 440
PP+ +L SP +L+ + + + P A PP L Q
Sbjct: 361 PPSQATTSLGSP--------------TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 406
Query: 441 ALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQP-SKEARACRTPESF 499
A PS S P L PSP + P+AL + +L + P S +A +P +
Sbjct: 407 APPSPPASPP--LSPLATPSPQA-------PNALAVHLLQAPFSPPPSPPVQAPFSPPAS 457
Query: 500 --LGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGRPTLNQMRTGSP 557
+ PSA+ + AP + +P + +PS T P A P +P
Sbjct: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP---------LAAP 508
Query: 558 ALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSA 617
L LA P AP P + P LP+ + FP F+P LP A
Sbjct: 509 PLQLAKPPPQAP------------PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 556
Query: 618 GPRPPPPQTGTNPFL 632
P P P P L
Sbjct: 557 TPPPQAPPVLAAPLL 571
Score = 52.4 bits (124), Expect = 1e-06
Identities = 85/336 (25%), Positives = 123/336 (36%), Gaps = 42/336 (12%)
Query: 325 IPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLT---PMLSSSEPWGRTPVLPA 381
IP P + S+ S +P S P+ R+ P T P+ S G T P
Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
Query: 382 GPP----TTDPWALNSPHHKLPSTGADPWGASLETSD-TPGGASTFDPFAKPPESTETKE 436
G + + + P A GA +TS TPG S A+ + T+
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP--AMARRSRAAGTEV 187
Query: 437 GLEQALPSGKPSSPVE----------LDLFGDPSPSSKQ-----NGTKEPDALDLGILGE 481
GL + PS +P P E +PSP++++ G + P + L
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 482 ALTQPSKEARACR-TPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFG 540
L+ P++ + R TP + PS L +L + PQV R L P ++P
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL-RPPQVTPPRKDAAPAL-GPLSSSPLA 305
Query: 541 AGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPL-----SSVPAGLTLPAS 595
P +Q P L P S+T + PLPL S+ P+ TLP+
Sbjct: 306 TPSPSAALQSQ---APPTL-----PATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSP 357
Query: 596 VSVFP-QAGAFAPQPLLPTPSSAGPRPPPPQTGTNP 630
+ P QA P L S P PP T P
Sbjct: 358 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP 393
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 55.8 bits (133), Expect = 1e-07
Identities = 93/340 (27%), Positives = 124/340 (36%), Gaps = 55/340 (16%)
Query: 312 APPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPM----- 366
A S SA P P R A G+ P A P P P G L +P +TP
Sbjct: 229 ASRSLSSSATPLSSPA-RSGPSARGTPRAP-AHPSQPKPKG--LQALRPPQVTPPRKDAA 284
Query: 367 -----LSSSE---PWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGA-SLETSDTPG 417
LSSS P P P+ PP+ L SP PS G+ +L+ + +
Sbjct: 285 PALGPLSSSPLATPSPSAPPSPSAPPSLQ--TLPSPPATPPSQATTSLGSPTLQATHSFL 342
Query: 418 GASTFDPFAKPPESTETKEGLE--QALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALD 475
+ P A PP L QA PS S P L PSP + P+AL
Sbjct: 343 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPP--LSPLATPSPQA-------PNALA 393
Query: 476 LGILGEALTQP-SKEARACRTPESF--LGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSA 532
+ +L + P S +A +P + + PSA+ + AP + +P + +
Sbjct: 394 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 453
Query: 533 PSPTNPFGAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTL 592
PS T P A P +P L LA P AP P + P L
Sbjct: 454 PSATPPPQAPPP---------LAAPPLQLAKPPPQAP------------PALATPPLQAL 492
Query: 593 PASVSVFPQAGAFAPQPLLPTPSSAGPRPPPPQTGTNPFL 632
P+ + FP F+P LP A P P P P L
Sbjct: 493 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 532
Score = 47.8 bits (112), Expect = 3e-05
Identities = 75/279 (26%), Positives = 102/279 (36%), Gaps = 53/279 (18%)
Query: 399 PSTGADPWGASLETSD-TPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVE----- 452
P A GA +TS TPG S A+ + T+ GL + PS +P P E
Sbjct: 142 PKRSALSAGARRDTSGPTPGTPSP--AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 199
Query: 453 -----LDLFGDPSPSSKQ-----NGTKEPDALDLGILGEALTQPSKEARACR-TPESFLG 501
+PSP++++ G + P + L L+ P++ + R TP +
Sbjct: 200 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 259
Query: 502 PSASSLVNLDSLVKAPQVAKTRN---PFLTGLSA-----PSPTNPFGAGEPGRPTLNQMR 553
PS L +L + PQV R P L LS+ PSP+ P P P Q
Sbjct: 260 PSQPKPKGLQAL-RPPQVTPPRKDAAPALGPLSSSPLATPSPSAP---PSPSAPPSLQTL 315
Query: 554 TGSPAL--GLAGGPVGAPLGSMTYS-------ASLPLPLSSVPAGLTLPASVSVFPQAGA 604
PA A +G+P T+S + L P P L LP + P A
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP-PLQAPPSPPA 374
Query: 605 FAPQPLLPTPSSAGPR------------PPPPQTGTNPF 631
P L TPS P PPP PF
Sbjct: 375 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 413
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 54.3 bits (129), Expect = 3e-07
Identities = 87/339 (25%), Positives = 126/339 (37%), Gaps = 39/339 (11%)
Query: 325 IPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLT---PMLSSSEPWGRTPVLPA 381
IP P + S+ S +P S P+ R+ P T P+ S G T P
Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
Query: 382 GPP----TTDPWALNSPHHKLPSTGADPWGASLETSD-TPGGASTFDPFAKPPESTETKE 436
G + + + P A GA +TS TPG S A+ + T+
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP--AMARRSRAAGTEV 187
Query: 437 GLEQALPSGKPSSPVE----------LDLFGDPSPSSKQ-----NGTKEPDALDLGILGE 481
GL + PS +P P E +PSP++++ G + P + L
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 482 ALTQPSKEARACR-TPESFLGPSASSLVNLDSLVKAPQVAKTRN---PFLTGLSAPSPTN 537
L+ P++ + R TP + PS L +L + PQV R P L LS+
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL-RPPQVTPPRKDAAPALGPLSSSPLAT 306
Query: 538 PFGAGEPGRPT--LNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPAS 595
P +G RP + T PA P+ PL S S P L ++P+ P S
Sbjct: 307 PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPS 366
Query: 596 VSVFPQAGAFAPQPLLPTPSSAGPRPP--PPQTGTNPFL 632
QA P + P S PP P + T+P L
Sbjct: 367 -----QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSL 400
Score = 53.1 bits (126), Expect = 7e-07
Identities = 100/461 (21%), Positives = 151/461 (32%), Gaps = 44/461 (9%)
Query: 179 SRGSPS---SYNSSSSSPRYT--SDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPAS 233
S GSP+ +++ + SPR T S +RP ++ + LQ L++ PAS
Sbjct: 417 SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL----------PAS 466
Query: 234 HRDEDLQLQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKL 293
LQ L+ +S + Q S ++ A + E + L
Sbjct: 467 ---PPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
Query: 294 KTSQSSILDLADIFVPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGT 353
+T +S+ +P+LAPP ++ P P + P + P T
Sbjct: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET 583
Query: 354 VLSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETS 413
S + P P +S P P P P T P P LP A P
Sbjct: 584 PSSIATPPPQAPPALASPPLQGLPSPPLSPLATPP-PQAPPXLALPPLQAPP-------- 634
Query: 414 DTPGGASTFDPFAKPPESTETKEGLE--QALPSGKPSSPVELDLFGDPSPSSKQNGTKEP 471
+P + P A P + QA S PS PV+ SP + T
Sbjct: 635 -SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 693
Query: 472 DALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLS 531
A +L P + + PSA+ + AP + +P +
Sbjct: 694 QA------PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPM 747
Query: 532 APSPTNPFGAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLT 591
+PS T P P + + P P P+ + P + P
Sbjct: 748 SPSATPP--------PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQA 799
Query: 592 LPASVSVFPQAGAFAPQPLLPTPSSAGPRPPPPQTGTNPFL 632
LP+ + FP F+P LP A P P P P L
Sbjct: 800 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 840
Score = 48.9 bits (115), Expect = 1e-05
Identities = 85/346 (24%), Positives = 121/346 (34%), Gaps = 73/346 (21%)
Query: 309 PALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPMLS 368
P + PP + P P + + ++ PS P+P + P L P
Sbjct: 283 PQVTPPRKDAA------PALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPP 336
Query: 369 SSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKP 428
+ P P P+ PP+ LPS A P + + TP P P
Sbjct: 337 LATPLPLAPPSPSAPPSL---------QTLPSPPATPPSQAPPSMTTP-------PMQAP 380
Query: 429 PESTETKEGLEQALPSGKPSSPVELDLFGDPSP--SSKQNGTKEPDALDLGILGEALTQP 486
P L+ P P S L PSP S T + L LT
Sbjct: 381 P-------SLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMS 433
Query: 487 SKEARACRTPES---FLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGE 543
++ +A T S P + L SL +P + + +P ++ LS+P +P A
Sbjct: 434 PRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQA-- 491
Query: 544 PGRPTLNQMRTGSPALGLAGGPVGAPLGSM------TYSASLPLPLSSVPAGLTLP---- 593
L+ + + SP APL S+ T S+ P L + PA LT P
Sbjct: 492 -----LSSLASHSPQ---------APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLEN 537
Query: 594 -ASVSVFPQAGAFAP--QPLLPTPSSAGPRP----------PPPQT 626
S++ P A AP P L TP P P PPP+T
Sbjct: 538 LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET 583
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 53.5 bits (127), Expect = 6e-07
Identities = 78/313 (24%), Positives = 114/313 (36%), Gaps = 21/313 (6%)
Query: 326 PGFRPN---TEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPMLSSSEPWGRTPVLPAG 382
PG+ P T S S GPS+ P+ P P G + P +P P G TP P+
Sbjct: 1559 PGYSPAWSPTPGSPGSPGPSS-PYIPSPGGAMSPSYSP--TSPAYEPRSPGGYTPQSPSY 1615
Query: 383 PPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKP--PESTETKEGLEQ 440
PT+ ++ SP + S P S S T S P P P + T
Sbjct: 1616 SPTSPSYSPTSPSYSPTSPNYSPTSPSY--SPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1673
Query: 441 ALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQPSKEARACRTPESFL 500
PS P+SP SP+S P P+ + + +P
Sbjct: 1674 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT----SPSYSPTSPSYSPTSPSYSP 1729
Query: 501 GPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNP-FGAGEPG-RPTLNQMRTGSPA 558
+ S + +P + T + + SPT+P + P PT SP+
Sbjct: 1730 TSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPS 1789
Query: 559 LGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAG 618
P +P S +YS S P P P+S S P + +++P TP+S
Sbjct: 1790 YS-PTSPSYSPT-SPSYSPSSPRYTPQSPT--YTPSSPSYSPSSPSYSPTSPKYTPTSPS 1845
Query: 619 PRPPPPQ-TGTNP 630
P P+ T T+P
Sbjct: 1846 YSPSSPEYTPTSP 1858
Score = 38.5 bits (88), Expect = 0.019
Identities = 48/170 (28%), Positives = 63/170 (37%), Gaps = 15/170 (8%)
Query: 309 PALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPMLS 368
P+ +P S S P + P T S S PS P SP S T S S +P S
Sbjct: 1697 PSYSPTSPSYSPTS---PSYSP-TSPSYSPTSPSYSPTSPSYSPTSPSYSPT---SPNYS 1749
Query: 369 SSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLET-----SDTPGGASTFD 423
+ P TP P+ PT+ ++ SP++ S P S S T S
Sbjct: 1750 PTSP-NYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSS 1808
Query: 424 PFAKP--PESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEP 471
P P P T + + PS P+SP SPSS + P
Sbjct: 1809 PRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSP 1858
>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 673
Score = 53.1 bits (126), Expect = 7e-07
Identities = 87/333 (26%), Positives = 126/333 (37%), Gaps = 50/333 (15%)
Query: 329 RPNTEASGSSWGPSADPWSPIPSGTVLSRSQPW------DLTPMLSSSEPWGRTP-VLPA 381
R + + S P+ P + P+GT SR+ P LT + S++ P G P P
Sbjct: 337 RASITRTPSRASPTGKPSTASPTGTP-SRASPTGSPSTASLTGLSSTASPTGTPPRASPT 395
Query: 382 GPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQA 441
G P+T P A P G TS T ST P PP ++ T +A
Sbjct: 396 GTPSTASLTRKPPR-------ASPTGMLSRTSITKMD-STASPTRTPPRASPTGTP-PRA 446
Query: 442 LPSGKPS---------------SPVELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQP 486
P+G PS SP G PS +S G+ +L +LT+
Sbjct: 447 SPTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASP-TGSPSRASLTRTPSRASLTKM 505
Query: 487 SKEARACRTPE--------SFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLS-APSPTN 537
A RTP S P+ S L ++ + A TR P L+ PS +
Sbjct: 506 ESTASITRTPSRASPTWTPSTASPTGSPSTAL-AMGSPSRAALTRTPSRASLTRTPSRAS 564
Query: 538 PFGAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVS 597
P R +L RT S L P +P G + ++ +P S++ + AS++
Sbjct: 565 ---LTTPSRASLT--RTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASIT 619
Query: 598 VFPQAGAFAPQPLLPTPSSAGPRPPPPQTGTNP 630
P + P +P+ PR P TGT P
Sbjct: 620 RTPPRASPTETPPRASPTGTPPRASP--TGTPP 650
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 52.8 bits (125), Expect = 1e-06
Identities = 82/335 (24%), Positives = 120/335 (35%), Gaps = 57/335 (17%)
Query: 342 SADPWSPIPSGTVLSRSQPWDLT--PMLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLP 399
+A P P P+ ++ P T +L+++ P P+L + P P A + + P
Sbjct: 850 AAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAP 909
Query: 400 STGADPW---GASLETSDTP------GGASTFDPFAKPPESTETKEGLEQ---------- 440
G G L P GGA P PP S + G +
Sbjct: 910 PPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPV 969
Query: 441 --ALPSG--KPSSPVELDLFGDPSPSSKQNGTKEPDALDLGIL----GEALTQPSKEARA 492
+ PSG P SP L P P+S+ P + + + G AL + A +
Sbjct: 970 PVSTPSGLVPPLSPATL-----PGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASS 1024
Query: 493 CRTPESFLGPSASSLVNLDSLVKA------PQVAKTRNPFLT----GLS-APSPTNPFGA 541
+ GP++S + SL + P ++ + P L G+S PSP P
Sbjct: 1025 QAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPAC 1084
Query: 542 GEPGRPTLNQMRTGSPALGLAGGPVGAP-----------LGSMTYSASLPLPLSSVPAGL 590
PG P + +GSPA + P+ P S T A+ LP
Sbjct: 1085 AAPGGPVITAFYSGSPA-PTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPAT 1143
Query: 591 TLPASVSVFPQAGAFAPQPLLPTPSSAGPRPPPPQ 625
PA S FP A A + L P + P P PQ
Sbjct: 1144 ATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQ 1178
Score = 44.7 bits (104), Expect = 3e-04
Identities = 95/409 (23%), Positives = 142/409 (34%), Gaps = 114/409 (27%)
Query: 306 IFVPALAPPSTHCSA--DPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDL 363
+F P + THC DP + PG A G +G + + P+ + S + + L
Sbjct: 494 VFSPVIRSSFTHCRPPLDP-EPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSL 552
Query: 364 TPMLSSSEPWG--------RTPVLPAGPPTTDPWALN-------SPHHKLPST--GADPW 406
++ G R P AG P T A + K P + G +P
Sbjct: 553 GSGTFKAQESGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPP 612
Query: 407 GASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPS--------GKPSSPVE------ 452
G S+ + GG + PP E +EG +PS G P++P+
Sbjct: 613 GPSVIAAPPSGGGNILQTLVLPPNKEE-QEGGGARVPSAPAPSLAYGAPAAPLSRPAATM 671
Query: 453 ------------LDLFGDPSPSSKQ----------------NGTKEPDALDLGILGEALT 484
+ + P P+S + G++ P LG+ +L
Sbjct: 672 VTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGV---SLV 728
Query: 485 QPSKEARACRTPESFL--GPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAG 542
K++ A +P L GP L ++ KAP +T L +P G G
Sbjct: 729 YSDKKSAAATSPAPHLVAGPL------LGTVGKAPAT-------VTNLLVGTP----GYG 771
Query: 543 EPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGL------------ 590
P P + + G+P G G GA GS + P+PL + G
Sbjct: 772 APAPPAVQFIAQGAPGGGTTAGS-GAGAGS---GPNGPVPLGILQPGALGKAGGITQVQY 827
Query: 591 ---TLPASVSVFPQAGAFAPQPLLPTPSSAGPRPP-------PPQTGTN 629
TLP + V P A AP P + +GP P PP T TN
Sbjct: 828 ILPTLPQQLQVAP---APAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTN 873
Score = 40.4 bits (93), Expect = 0.005
Identities = 77/316 (24%), Positives = 106/316 (33%), Gaps = 88/316 (27%)
Query: 327 GFRPNTEASGS--SWGPSADPWSPIPSGTVLSRSQPWDLTPMLSSSEPWGRTPVLPAGPP 384
G P + +G+ S+GP++ S T L S P + P+LS+ G+ P+L G
Sbjct: 1018 GTSPASSQAGTVTSYGPTS---SVALGFTSLGPSGPAFVQPLLSA----GQAPLLAPGQV 1070
Query: 385 TTDPWALNSPHHKLPSTGADPWGASLET--SDTPGGASTFDPFAKPPES---------TE 433
P P +LP A P G + S +P S+ P A+P ++ T
Sbjct: 1071 GVSP----VPSPQLPPACAAPGGPVITAFYSGSPAPTSSA-PLAQPSQAPPSLVYTVATS 1125
Query: 434 TKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQPSKEARAC 493
T LP G P+ P+P+S P A A
Sbjct: 1126 TTPPAATILPKGPPAPAT-----ATPAPTS----------------------PFPSATAG 1158
Query: 494 RTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGRPTLNQMR 553
S + P A KAPQ K A P F AG GRP
Sbjct: 1159 SMTYSLVAPKAQR-----PSPKAPQKVKAA-------IASIPVGSFEAGASGRPG----- 1201
Query: 554 TGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPT 613
+P L GPV P + P P + P P+ PT
Sbjct: 1202 -PAPRQPLEPGPVREPTAPESELEGQPTPPAPPPL------------------PETWTPT 1242
Query: 614 PSSAGPRPPPPQTGTN 629
S+ P PPP + T+
Sbjct: 1243 ARSSPPLPPPAEERTS 1258
Score = 31.6 bits (70), Expect = 2.3
Identities = 27/88 (30%), Positives = 34/88 (38%), Gaps = 14/88 (15%)
Query: 552 MRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLL 611
M+ +P G P+ T +A+ P P S PAG P S S +G P L
Sbjct: 1519 MQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPS-PAGGPDPTSPS--SDSGTAQAAPPL 1575
Query: 612 PTPSSAG-----------PRPPPPQTGT 628
P P +G P PPPP T
Sbjct: 1576 PPPPESGPGQPGWEGAPQPSPPPPGPST 1603
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 52.4 bits (124), Expect = 1e-06
Identities = 135/567 (23%), Positives = 193/567 (34%), Gaps = 118/567 (20%)
Query: 113 DRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSRRY 172
D D +D+ N E A KDE +E T ++ T + A
Sbjct: 1067 DSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSS-------------- 1112
Query: 173 GEDYSRSRGSPSSYNSSSSSPRYTSDLEQ--ARPQTSGEEELQLQLALAMS--------R 222
S S S +SS SSP + D E+ AR + EEE ++ +M+ +
Sbjct: 1113 ----SESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQ 1168
Query: 223 EEAEKPVPPASHRDEDLQLQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREP 282
+ E + P + + L ++ + + + E R D P+ G E
Sbjct: 1169 DGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGV----------EE 1218
Query: 283 EREERKEEEKLKTSQSSILDLADIFVPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPS 342
+ R+ E+ SQ + L+ PP+ A P P P +
Sbjct: 1219 PADSREPPEEPGLSQEGAMLLSP------EPPAKEVEARPPLSPERAPEHDLE------- 1265
Query: 343 ADPWSPIPSGTVLSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTTD---------PWALNS 393
+P P+ P L P L P R P P P TTD P A +
Sbjct: 1266 VEPEPPM--------MLPLPLQPPLPPPRP-PRPPSPPPEPETTDASHPSVPPEPLAEDH 1316
Query: 394 PHHKLPSTGADPWGASLETSD-TPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVE 452
P H G+ S ET TPGG +PP S + GL + P P SP
Sbjct: 1317 PPHTPGLCGSLAKSQSTETVPATPGG--------EPPLSGGSS-GLSLSSPQ-VPGSPFS 1366
Query: 453 LDLFGDPSPSSKQNGTKEPDALDLGILGEALTQPSKEAR--ACRTP----ESFLGPSASS 506
+ PSPS G D ++PS C P + GP AS
Sbjct: 1367 ---YPAPSPSLSSGGLPRTPGRDFSFT-PTFSEPSGPLLLPVCPLPTGRRDERSGPLASP 1422
Query: 507 LV-----------------NLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGRPTL 549
++ L ++++A A T P L S P +PGRP
Sbjct: 1423 VLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKR-KPGRP-- 1479
Query: 550 NQMRTGSPALGLAGGPVGAPLGSMTYSASLPL----PLSSVPAGLTLPASVSV-FPQAGA 604
R P++ GP+ P L L P + V P +V++ F AG
Sbjct: 1480 ---RRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGI 1536
Query: 605 FAPQPLLPTPSSAGPRPPPPQTGTNPF 631
AP P LP P PPP + PF
Sbjct: 1537 PAPPPPLPPQPPPPPPPPPVEPTKLPF 1563
Score = 41.2 bits (95), Expect = 0.003
Identities = 85/353 (24%), Positives = 117/353 (33%), Gaps = 76/353 (21%)
Query: 334 ASGSSWGPSADPWSPIP--SGTVLSRSQPWDLTP---MLSSSEPWGRTPVLPAGPPTTDP 388
A G + G S P+ P S T P TP S+ P+ +TPV PP +P
Sbjct: 356 AVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPY-QTPVAHFPPPPEEP 414
Query: 389 WAL-------NSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQA 441
A + + P+ P L + PG P PP T + E
Sbjct: 415 TATAAFGARDSGEFRRAPAPPPLPPAEPL-AKEKPG-----TPPGPPPPDTNSME----- 463
Query: 442 LPSGKPS---SPVELDLFGDPSPSSKQNGTKEP-DALDLGIL---------------GEA 482
G+P+ SP D G P+ S G ++P D+LD I ++
Sbjct: 464 -LGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDS 522
Query: 483 LTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPT------ 536
T+ E + S L P A N + P +R P TGL SPT
Sbjct: 523 DTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSR-PSSTGLEDISPTPLPDSD 581
Query: 537 ---------NPFGAGEPGRPTLNQM--RTGSPALGLAGG--PVGAPLGSMTYSA------ 577
P EPG P + +T AL L G P + S+
Sbjct: 582 EDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEI 641
Query: 578 ------SLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPRPPPP 624
S P+ + P + + + AP LP P P PPPP
Sbjct: 642 SDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPP 694
Score = 33.5 bits (75), Expect = 0.61
Identities = 79/320 (24%), Positives = 107/320 (33%), Gaps = 41/320 (12%)
Query: 314 PSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPMLSSSEPW 373
P+ S +P D PG P E+S + GP S +L + Q T +L EP
Sbjct: 468 PTFGWSPEPCDSPG-TPTLESSPA--GPEKPHDSLDSRIEMLLKEQR---TKLLFLREPD 521
Query: 374 GRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKPPESTE 433
T + G P + + SP P+G T+ PG PP S
Sbjct: 522 SDTELQMEGSPISSSSSQLSP--------LAPFG----TNSQPGFRGP-----TPPSSRP 564
Query: 434 TKEGLEQALPSGKPSSPV--ELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQPSKEAR 491
+ GLE P+ P S ELDL P P + G +P G+L + + + +
Sbjct: 565 SSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEP-GPPDP----AGLLSQT-AEVALDLV 618
Query: 492 ACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGRPTLNQ 551
RTP S D + ++ +T P P PG +
Sbjct: 619 GDRTPTSEKMDEGQQSSGEDMEISDDEMPSAP---ITSADCPKPM----VVTPGAAAVAA 671
Query: 552 MRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLL 611
+P L L P PL P P P LP P A P
Sbjct: 672 PSVLAPTLPLPPPPGFPPLPP---PPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPP 728
Query: 612 PTPSSAGPRPPPPQTGTNPF 631
P P+ G PPP PF
Sbjct: 729 PLPAPPGVPPPPILPPLPPF 748
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 52.0 bits (123), Expect = 2e-06
Identities = 91/341 (26%), Positives = 131/341 (38%), Gaps = 43/341 (12%)
Query: 308 VPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPML 367
+P L PP + P + P EAS S P P SP+P LSR P + +P+
Sbjct: 438 MPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSR--PLEESPL- 494
Query: 368 SSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGAD--PWGASLET--SDTPGGASTFD 423
S P +P+ P PP + P+ SP + P + + P +LET S P +
Sbjct: 495 --SPPPEESPLSP--PPESSPF---SPLEESPLSPPEESPPSPALETPLSPPPEASPLSP 547
Query: 424 PFAKPPESTETKEGLEQALPSGKP------SSPVELDLFGDPSPSSKQNGTKEPDALDLG 477
PF + P S +E LP+ P S P E P S + E L
Sbjct: 548 PFEESPLSPPPEE-----LPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP 602
Query: 478 ILGEALTQPSKEARACRTPE-SFLGP-----SASSLVNLDSLVKAPQVAK-TRNPFLTGL 530
L+ P +E+ PE S L P S + P+V++ + P ++ L
Sbjct: 603 FEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRL 662
Query: 531 SAP---SPTNPFGAGEPGRPTLNQMRTGSPA--LGLAGGPVGAPLGSMTYSASLPLPLSS 585
S P SP +P P P R P + P +P + + LPL
Sbjct: 663 SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEE 722
Query: 586 VPAGLTLPASVSVFPQAGA--FAPQPLLPTPSSAGPRPPPP 624
P L LP + P++ +P+P P S PRP P
Sbjct: 723 SPL-LPLPEEPQLCPRSEGPHLSPRPEEPHLS---PRPEEP 759
Score = 41.6 bits (96), Expect = 0.002
Identities = 86/312 (27%), Positives = 116/312 (37%), Gaps = 59/312 (18%)
Query: 341 PSADP-WSPIPSGTVLSRSQPWDLTPMLSSSEPWGRTPVLPAGPP----TTDPWALNSPH 395
P+A P + P PS T + +QP PML +S G AG P TT P +P
Sbjct: 2190 PTAPPTYPPYPSPTG-APAQP----PMLGASSRPG------AGQPGEFHTTPP---GTPR 2235
Query: 396 HK--LPSTGADPWGASLETSDTP-----GGASTFDPFAKPPESTETKEGLE---QALPSG 445
H+ P P SL+ P GG +P PP E+++ LE + L +
Sbjct: 2236 HQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGAS 2295
Query: 446 KPS-SPVELDLFGDPSPSSKQNG--TKEPDALDLGILGEA-LTQPSKEARACRTPESFLG 501
PS P L PS + G K PD + A +P R E
Sbjct: 2296 SPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEP--- 2352
Query: 502 PSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGRPTLNQMRTGSPALGL 561
P A +L AP + F G S T+P+ +P P + + P
Sbjct: 2353 PPAQAL--------APSPPSHPDIFRPG----SYTDPY--AQP--PLTPRPQPPPPESCC 2396
Query: 562 AGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGP-- 619
A P P + + P SS + LT P +S A AF P P+ P S P
Sbjct: 2397 ALPPRSLPSDPFSRVPASPQSQSSSQSPLT-PRPLS----AEAFCPSPVTPRFQSPDPYS 2451
Query: 620 RPPPPQTGTNPF 631
RPP +PF
Sbjct: 2452 RPPSRPQSRDPF 2463
Score = 41.2 bits (95), Expect = 0.003
Identities = 97/372 (26%), Positives = 132/372 (35%), Gaps = 90/372 (24%)
Query: 278 RDREPEREERKEEEKLKTSQSSILDLADIFVPALAPPST--HCSADPWDIPGFRPNTEAS 335
+ EP R EE L S L+ + PP C A P ++P F P E S
Sbjct: 836 QSEEPCLSPRPEESHL----SPELEKPPLSPRPEKPPEEPGQCPA-PEELPLFPPPGEPS 890
Query: 336 GSSW-------GPSADPWSPIPSGTVLSRSQPWDLTPMLSSSEPW--GRTPVL-PAGPPT 385
S P P SP+P LS S L+P L +P +P++ A PP
Sbjct: 891 LSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPA 950
Query: 386 TDPWALNSPHHKLPSTG-ADPWGASLETSDTPGGASTFD-PFAKPPESTETKEGLEQALP 443
P L + + G +DP ++P A + P + PPE+ T
Sbjct: 951 LSP--LGELEYPFGAKGDSDP--------ESPLAAPILETPISPPPEANCT--------- 991
Query: 444 SGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQPSKEARACRTPESFLGPS 503
+P P+ L PSP S +G L +P L P
Sbjct: 992 DPEPVPPMIL----PPSPGS-----------PVGPASPILMEP-------------LPPQ 1023
Query: 504 ASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFG--AGEPGRPTLNQMRTGS----- 556
S L+ SLV +P LS PSP +P G G L++M T
Sbjct: 1024 CSPLLQ-HSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPE 1082
Query: 557 -PAL-GLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTP 614
PAL A P+ +P+G ++ A P P +GL P G AP
Sbjct: 1083 CPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGL----GEDTAPLDGIDAP------- 1131
Query: 615 SSAGPRPPPPQT 626
G +P P QT
Sbjct: 1132 ---GSQPEPGQT 1140
Score = 38.5 bits (88), Expect = 0.019
Identities = 45/170 (26%), Positives = 62/170 (36%), Gaps = 40/170 (23%)
Query: 309 PALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPMLS 368
P PP + C+ P +P +DP+S +P+ S LTP
Sbjct: 2387 PQPPPPESCCALPPRSLP----------------SDPFSRVPASPQSQSSSQSPLTPRPL 2430
Query: 369 SSEPWGRTPVL------------PAGPPTTDPWA-LNSPHHKLPSTGADPWGASLETSDT 415
S+E + +PV P+ P + DP+A L+ P P A G+ TS
Sbjct: 2431 SAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLG 2490
Query: 416 PGGASTFDPFAKPPESTETKEGLEQALPSGKP----SSPVELDLFGDPSP 461
GG P E L +PSG+P SP G PSP
Sbjct: 2491 AGGFPAALPAGPAGE-------LHAKVPSGQPPNFVRSPGTGAFVGTPSP 2533
Score = 38.1 bits (87), Expect = 0.025
Identities = 82/343 (23%), Positives = 116/343 (33%), Gaps = 76/343 (22%)
Query: 309 PALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPS-GTVLSRSQ-------P 360
P L+PP S ++ + AS S+GP + PS GT L +
Sbjct: 2271 PLLSPPPFGESRKALEVK--KEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFK 2328
Query: 361 WDLTPMLSSSEPWGRTPVL---PAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPG 417
LTP S EP ++P L P PP A + P H D
Sbjct: 2329 APLTPRASQVEP--QSPGLGLRPQEPPPAQALAPSPPSHP----------------DIFR 2370
Query: 418 GASTFDPFAKPPESTETKEGLEQAL----PSGKPSSPVELDLFGDPSPSSKQNGTKEPDA 473
S DP+A+PP + + ++ P PS P P+S Q+ +
Sbjct: 2371 PGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSR------VPASPQSQSSSQSP 2424
Query: 474 LDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAP 533
L L PS ++P+ + P P ++R+PF P
Sbjct: 2425 LTPRPLSAEAFCPSPVTPRFQSPDPYSRP--------------PSRPQSRDPFAPLHKPP 2470
Query: 534 SPTNPFGAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLP 593
P P A + G + G L GP G + VP+G P
Sbjct: 2471 RPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGE-------------LHAKVPSG--QP 2515
Query: 594 ASVSVFPQAGAF--APQPLLPT-PSSAGP---RPPPPQTGTNP 630
+ P GAF P P+ T P + G +PP PQ G P
Sbjct: 2516 PNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPP 2558
Score = 37.0 bits (84), Expect = 0.055
Identities = 80/333 (24%), Positives = 113/333 (33%), Gaps = 32/333 (9%)
Query: 309 PALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLS---RSQPWDLTP 365
P PP P++ P E S S P A SP P + +S P P
Sbjct: 589 PMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPP 648
Query: 366 MLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLET--SDTPGGASTFD 423
+S P PV+ P + L+ P + P T P + L D+P D
Sbjct: 649 EVSRLSP---LPVVSRLSPPPEESPLSPPPEESP-TSPPPEASRLSPPPEDSPTSPPPED 704
Query: 424 -PFAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNG---TKEPDALDLGIL 479
P + PPE + LE++ P P P S + + P+ L
Sbjct: 705 SPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQ 764
Query: 480 GEA--LTQPSKEARACRTPES-FLGPSASS---LVNLDSLVKAPQVAKTRNPFLTGLSAP 533
E L+ +E C PE L P A + L +PQ T P L+ P
Sbjct: 765 AEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQ---TEEPHLS----P 817
Query: 534 SPTNPFGAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASL---PLPLSSVPAGL 590
P P + +P L+ S L+ P + L L P P
Sbjct: 818 VPEEPCLSPQPEESHLSPQ---SEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQC 874
Query: 591 TLPASVSVFPQAGAFAPQPLLPTPSSAGPRPPP 623
P + +FP G + PLL P+ + P PP
Sbjct: 875 PAPEELPLFPPPGEPSLSPLLGEPALSEPGEPP 907
Score = 35.0 bits (79), Expect = 0.21
Identities = 68/288 (23%), Positives = 100/288 (34%), Gaps = 53/288 (18%)
Query: 350 PSGTVLSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGAS 409
P G ++ QP + P+ ++P G+ V P P LN LP P
Sbjct: 396 PKGGHVTSMQPKEPGPLQCEAKPLGKAGV-QLEPQLEAP--LNEEMPLLPPPEESPLSPP 452
Query: 410 LETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTK 469
E S P + PPE++ E+ P+SP+
Sbjct: 453 PEES----------PTSPPPEASRLSPPPEEL-----PASPL------------------ 479
Query: 470 EPDALDLGI-LGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFL- 527
P+AL L L E+ P E P P +S L+ +P +P L
Sbjct: 480 -PEALHLSRPLEESPLSPPPEESPLSPP-----PESSPFSPLEESPLSPPEESPPSPALE 533
Query: 528 TGLSAP---SPTNPFGAGEPGRPTLNQMRTGSP--ALGLAGGPVGAPLGSMTYSASLPLP 582
T LS P SP +P P P ++ T P A L+ P +P+ + P
Sbjct: 534 TPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEES----P 589
Query: 583 LSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPRPPPPQTGTNP 630
+S P L P + PL P P ++ PPP + +P
Sbjct: 590 MSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSP 637
Score = 33.5 bits (75), Expect = 0.61
Identities = 60/213 (28%), Positives = 81/213 (38%), Gaps = 38/213 (17%)
Query: 431 STETKEGLEQALPSGKPSSPVELDLFGDPS---PSSKQNGTKEPDALDLGILGEALTQPS 487
S + ++ + AL G P+ P L F P P+ G KE + +D + EA PS
Sbjct: 3986 SPQQQQQQQVALGPGMPAKP--LQHFSSPGALGPTLLLTG-KEQNTVDPAVSSEATEGPS 4042
Query: 488 KEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPG-- 545
GP A +S+ P K P L+G S P +P
Sbjct: 4043 THQG---------GPLAIGTTP-ESMATEPGEVK---PSLSGDSQLLLVQPQPQPQPSSL 4089
Query: 546 --RPTLN---QMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFP 600
+P L Q + L AGG LGS + S + SSVP L P SVS+
Sbjct: 4090 QLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEA-----SSVPHLLAQP-SVSLGD 4143
Query: 601 QAGAFAP------QPLLPTPSSAGPRPPPPQTG 627
Q G+ QP+L P P PP+ G
Sbjct: 4144 QPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPG 4176
Score = 33.1 bits (74), Expect = 0.80
Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 5/70 (7%)
Query: 563 GGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQ--PLLPTPSSAGPR 620
G P G + SM PL + P G A V + PQ A + PLLP P +
Sbjct: 394 GQPKGGHVTSMQPKEPGPLQCEAKPLG---KAGVQLEPQLEAPLNEEMPLLPPPEESPLS 450
Query: 621 PPPPQTGTNP 630
PPP ++ T+P
Sbjct: 451 PPPEESPTSP 460
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 52.0 bits (123), Expect = 2e-06
Identities = 83/356 (23%), Positives = 121/356 (33%), Gaps = 61/356 (17%)
Query: 277 QRDREPEREERKEEEKLKTSQSSILDLADIFVPALAPPSTHCSADPWDIPGFRPNTEASG 336
Q+D P+ ++ EK+K+ I P P + H P RP T+ +
Sbjct: 231 QQDGTPKSISSQQPEKIKSQPPGTGK--PIQGPTQTPQTDHAKL-PLQRDASRPQTKQAD 287
Query: 337 SSWGPSADPWSPIPSGTVLSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTTDPWALNSPHH 396
G S P P PS + + P G+ P G + P P
Sbjct: 288 IVRGESVKPSLPSPSKPPIQQPTP-------------GKPPAQQPGHEKSQPGPAKPP-- 332
Query: 397 KLPSTGADPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLF 456
A P G + + PG T P +PP +T+ P +P P +
Sbjct: 333 ------AQPSGLTKPLAQQPG---TVKPPVQPPGTTK---------PPAQPLGPAK---- 370
Query: 457 GDPSPSSKQNGTKEPDALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDS---L 513
P ++Q G+++P + G +AL QP + TP GP+ + + L
Sbjct: 371 ----PPAQQTGSEKPSSEQPG--PKALAQPPGVGK---TPAQQPGPAKPPTQQVGTPKPL 421
Query: 514 VKAPQV---AKTRNPFLTGLSAPSPTN-PFGAGEPGRPTLNQMRTGSPALGLAGGPVGAP 569
+ P + AK P T + P P P PG+ + Q P L G P P
Sbjct: 422 AQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG-PAKPP 480
Query: 570 LGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPRPPPPQ 625
+ P S P S PQ P P P+P G PP Q
Sbjct: 481 PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQ----PGPAKPSPQQPGSTKPPSQ 532
Score = 37.7 bits (86), Expect = 0.032
Identities = 82/341 (24%), Positives = 115/341 (33%), Gaps = 44/341 (12%)
Query: 309 PALAPPSTHCSADPWDIPG-FRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPML 367
P+ P ST P PG +P+ + GS+ PS P S PS S ++P
Sbjct: 500 PSQQPGSTK---PPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKP----SAQ 552
Query: 368 SSSEPWGRTPV-LPAGPPTTDPWALNSPHHKLPSTGAD-----------PWGASLET-SD 414
S++P +T P PPT P A P LP T P A+ T ++
Sbjct: 553 QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTE 612
Query: 415 TPGGASTFDPFAKPPESTETKEGL----EQALPSGKPSSPVELDLFGDPSPSSKQNGTKE 470
+ F P TE KE L + G +PV P P K
Sbjct: 613 CQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVP----SSPQPKLKTAPVTT 668
Query: 471 PDALDLGILGEALTQPSKEAR----ACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPF 526
A+ T P K+A + PE P LV +L +P + P
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP---PLVKQPTLHGSPSAKAKQPPE 725
Query: 527 LTGLSAPSPTNPFGAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSV 586
LS P+P P P + P P + S + + +P S V
Sbjct: 726 ADSLSKPAP--PKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV 783
Query: 587 PA----GLTLPASVSVFPQAGAFAP--QPLLPTPSSAGPRP 621
+ T P + +F P + + P S A PRP
Sbjct: 784 QSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRP 824
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 52.0 bits (123), Expect = 2e-06
Identities = 83/356 (23%), Positives = 121/356 (33%), Gaps = 61/356 (17%)
Query: 277 QRDREPEREERKEEEKLKTSQSSILDLADIFVPALAPPSTHCSADPWDIPGFRPNTEASG 336
Q+D P+ ++ EK+K+ I P P + H P RP T+ +
Sbjct: 231 QQDGTPKSISSQQPEKIKSQPPGTGK--PIQGPTQTPQTDHAKL-PLQRDASRPQTKQAD 287
Query: 337 SSWGPSADPWSPIPSGTVLSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTTDPWALNSPHH 396
G S P P PS + + P G+ P G + P P
Sbjct: 288 IVRGESVKPSLPSPSKPPIQQPTP-------------GKPPAQQPGHEKSQPGPAKPP-- 332
Query: 397 KLPSTGADPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLF 456
A P G + + PG T P +PP +T+ P +P P +
Sbjct: 333 ------AQPSGLTKPLAQQPG---TVKPPVQPPGTTK---------PPAQPLGPAK---- 370
Query: 457 GDPSPSSKQNGTKEPDALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDS---L 513
P ++Q G+++P + G +AL QP + TP GP+ + + L
Sbjct: 371 ----PPAQQTGSEKPSSEQPG--PKALAQPPGVGK---TPAQQPGPAKPPTQQVGTPKPL 421
Query: 514 VKAPQV---AKTRNPFLTGLSAPSPTN-PFGAGEPGRPTLNQMRTGSPALGLAGGPVGAP 569
+ P + AK P T + P P P PG+ + Q P L G P P
Sbjct: 422 AQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG-PAKPP 480
Query: 570 LGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPRPPPPQ 625
+ P S P S PQ P P P+P G PP Q
Sbjct: 481 PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQ----PGPAKPSPQQPGSTKPPSQ 532
Score = 37.7 bits (86), Expect = 0.032
Identities = 82/341 (24%), Positives = 115/341 (33%), Gaps = 44/341 (12%)
Query: 309 PALAPPSTHCSADPWDIPG-FRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPML 367
P+ P ST P PG +P+ + GS+ PS P S PS S ++P
Sbjct: 500 PSQQPGSTK---PPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKP----SAQ 552
Query: 368 SSSEPWGRTPV-LPAGPPTTDPWALNSPHHKLPSTGAD-----------PWGASLET-SD 414
S++P +T P PPT P A P LP T P A+ T ++
Sbjct: 553 QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTE 612
Query: 415 TPGGASTFDPFAKPPESTETKEGL----EQALPSGKPSSPVELDLFGDPSPSSKQNGTKE 470
+ F P TE KE L + G +PV P P K
Sbjct: 613 CQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVP----SSPQPKLKTAPVTT 668
Query: 471 PDALDLGILGEALTQPSKEAR----ACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPF 526
A+ T P K+A + PE P LV +L +P + P
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP---PLVKQPTLHGSPSAKAKQPPE 725
Query: 527 LTGLSAPSPTNPFGAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSV 586
LS P+P P P + P P + S + + +P S V
Sbjct: 726 ADSLSKPAP--PKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV 783
Query: 587 PA----GLTLPASVSVFPQAGAFAP--QPLLPTPSSAGPRP 621
+ T P + +F P + + P S A PRP
Sbjct: 784 QSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRP 824
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 50.8 bits (120), Expect = 4e-06
Identities = 79/352 (22%), Positives = 111/352 (31%), Gaps = 53/352 (15%)
Query: 312 APPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPMLSSSE 371
+PP+T S P P T S + + P + PS + + + P P + S
Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTP---PPTTTPSP 1456
Query: 372 PWGRT----PVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDT------PGGAST 421
P T P PPTT P + +T P + + T P +T
Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTT 1516
Query: 422 FDPFAKP-PESTETKEGLEQALPSGKPSSPVE-------LDLFGDPSPSSKQNGTKEPDA 473
P P P +T T PS ++P+ L PSP T P
Sbjct: 1517 LPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPT- 1575
Query: 474 LDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAP 533
T PS +P P+ ++ + +P T P T +P
Sbjct: 1576 ----------TTPSPPTTTTPSP-----PTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP 1620
Query: 534 SPTNPFGAGEPGRPTLNQMRTGSP--ALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLT 591
T P TL T SP P P T + S P+ ++ P T
Sbjct: 1621 PTTTPI-TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTT 1679
Query: 592 LPAS-------------VSVFPQAGAFAPQPLLPTPSSAGPRPPPPQTGTNP 630
P+S + P +P TPSS PPP T T P
Sbjct: 1680 TPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTP 1731
Score = 42.4 bits (98), Expect = 0.001
Identities = 64/275 (23%), Positives = 88/275 (32%), Gaps = 48/275 (17%)
Query: 311 LAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSG-TVLSRSQPWDLTPMLSS 369
+ PP++ + P P P T + + P + PS T+ + + P TP +
Sbjct: 1547 ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPT 1606
Query: 370 SEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSD----TPGGASTFDPF 425
+ P PPTT P + LP T + T+ TP +T P
Sbjct: 1607 TTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP- 1665
Query: 426 AKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQ 485
PP +T T P+ PSSP+ PSP + T P T
Sbjct: 1666 -SPPITTTTTPP-----PTTTPSSPITTT----PSPPTTTMTTPSPT-----------TT 1704
Query: 486 PSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPG 545
PS TP S PS P T ++ PSPT
Sbjct: 1705 PSSPITTTTTPSSTTTPS---------------------PPPTTMTTPSPTTTPSPPTTT 1743
Query: 546 RPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLP 580
TL T SP P P +S + P
Sbjct: 1744 MTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTP 1778
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 48.9 bits (115), Expect = 1e-05
Identities = 63/259 (24%), Positives = 91/259 (35%), Gaps = 32/259 (12%)
Query: 399 PSTGADPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQA-LPSGKPSS-PVELDLF 456
P TG + T+ G + P P + L A + G+P+ + + L
Sbjct: 503 PHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLA 562
Query: 457 GDPSPSSKQNGTKEPDALDLGILGEALTQPSKEARACRTPESFLGPS--------ASSLV 508
P+ Q P A + + +T P TP+ + P+ A+ ++
Sbjct: 563 AGSLPTQSQPAPAGPAATTVL---QGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVL 619
Query: 509 NLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGRPTLNQMRTGSPALGLAGGPVGA 568
+ +AP T P GL P P A P Q T P+ GLA P
Sbjct: 620 TVQPAPQAPPAVST--PLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKI 677
Query: 569 PLG---SMTYSASLPL--------------PLSSVPAGLTLPASVSVFPQAGAFAPQPLL 611
LG S T +A L PLS+ L++PASV V A P P
Sbjct: 678 VLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPAT 737
Query: 612 PTPSSAGPRPPPPQTGTNP 630
P AG P P + +P
Sbjct: 738 PVAKGAGLGPQAPDSQASP 756
Score = 44.7 bits (104), Expect = 3e-04
Identities = 85/335 (25%), Positives = 120/335 (35%), Gaps = 52/335 (15%)
Query: 310 ALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPMLSS 369
A APP + P PG + E PSA P + + ++ LS+
Sbjct: 655 AAAPPQ---ATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSA 711
Query: 370 SEPWGRTP---VLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFA 426
P P ++ A PP DP A +P K G P + S P P A
Sbjct: 712 EGPHLSVPASVIVSAPPPAQDP-APATPVAK--GAGLGPQAPDSQASPAPAPQI---PAA 765
Query: 427 KPPESTETKEGLEQALPSGKPSSPVELDLFGD----PSPSSKQNGTKEPDALDLGILGEA 482
P L+ PS PS P + L GD PSP + ++ P ++
Sbjct: 766 AP---------LKGPGPSSSPSLPHQAPL-GDSPHLPSPHPTRPPSRPPSR------PQS 809
Query: 483 LTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAG 542
+++P E P P+ + + + + P A S P+PT P
Sbjct: 810 VSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPA----------SNPAPTAPGPPQ 859
Query: 543 EPGRPTLNQMRTGS--PALGLAGGPVGAPLGSMTYSAS-LPLPLSSVPAGLTLPASVSVF 599
P RP +Q G PA L + + S + ++S LP P P+ L S
Sbjct: 860 PPLRPQ-SQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAP---TPSDFQLQFPPSQG 915
Query: 600 PQAGAFAPQPLLPTPSSAGPRPPPPQT---GTNPF 631
P P L P A P PPPP+T T PF
Sbjct: 916 PHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPF 950
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 48.5 bits (114), Expect = 2e-05
Identities = 94/334 (28%), Positives = 121/334 (36%), Gaps = 65/334 (19%)
Query: 314 PSTHCSADPWDIPGFRPNTEAS-----GSSWGPSADPWSPIPSGTVLSRSQPWDLTPMLS 368
PS SA PG P T +S S GP++ P PIP+ + L+ ++ LS
Sbjct: 1381 PSPEVSASA---PGAAPLTISSPLHVPSSLPGPASSPM-PIPNSSPLASPVSSTVSVPLS 1436
Query: 369 SSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKP 428
SS P LPA P + P L P + A G +L TS TP A P
Sbjct: 1437 SSLPISVPTTLPA--PASAP--LTIPISAPLTVSAS--GPALLTSVTPPLAPVVPAAPGP 1490
Query: 429 PESTETKEGLEQALPSG-KPS-SPVELDLFGDPSPSSKQ------------------NGT 468
P PSG PS S + L L PS SS Q N T
Sbjct: 1491 PSLA----------PSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNST 1540
Query: 469 KEPDALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLT 528
P + + AL P A ++ L ASS + AP A T
Sbjct: 1541 VAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQ-----T 1595
Query: 529 GLSAPSPTNPFG-----AGEPGR-PTLNQMRTGSPALG---------LAGGPVGAPLGSM 573
+ APSP P A PG P L +T P + + PV AP +
Sbjct: 1596 AILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVL 1655
Query: 574 TYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAP 607
S++ + + VP+ L PAS A A AP
Sbjct: 1656 APSSTQTMLPAPVPSPLPSPASTQTLALAPALAP 1689
Score = 45.1 bits (105), Expect = 2e-04
Identities = 71/269 (26%), Positives = 97/269 (36%), Gaps = 40/269 (14%)
Query: 376 TPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKPPESTETK 435
+P + A P P ++SP H +PS+ P + +P P A P ST +
Sbjct: 1382 SPEVSASAPGAAPLTISSPLH-VPSSLPGP-------ASSPMPIPNSSPLASPVSSTVSV 1433
Query: 436 EGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQPSKEARACRT 495
L +LP P++ P+P+S L + G AL A
Sbjct: 1434 P-LSSSLPISVPTTL--------PAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVV 1484
Query: 496 PE---------SFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGR 546
P S PSAS+L L AP ++ ++ P L AP+ ++ G
Sbjct: 1485 PAAPGPPSLAPSGASPSASALTL--GLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVA 1542
Query: 547 PTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFA 606
P + + PA LA AP ASL P SS L P + PQ A
Sbjct: 1543 PACSPVLV--PASALASPFPSAP-NPAPAQASLLAPASSASQALATPLAPMAAPQTAILA 1599
Query: 607 PQ---PLLPTPSSAGPRPPPPQTGTNPFL 632
P PL P P A P G P L
Sbjct: 1600 PSPAPPLAPLPVLA------PSPGAAPVL 1622
Score = 39.3 bits (90), Expect = 0.011
Identities = 96/348 (27%), Positives = 126/348 (36%), Gaps = 115/348 (33%)
Query: 311 LAPPSTHCSADPWDIPGFRPNTEASGSS-WGPSADPWSPIPSGTVLSRSQPWDLTPMLSS 369
LAP S+H +PG + S P++ SP PS + +Q L P S+
Sbjct: 1527 LAPTSSH-------VPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSA 1579
Query: 370 SEPWGRTPVLPAGPPTTDPWALNSPHHKL-------PSTGADPWGASLET-------SDT 415
S+ TP+ P P T A SP L PS GA P AS +T S T
Sbjct: 1580 SQALA-TPLAPMAAPQTAILA-PSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSST 1637
Query: 416 PGGA-STFDPFAKP-----PESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTK 469
PG + ++ P P P ST+T LP+ PS P+ PSP+S Q
Sbjct: 1638 PGTSLASASPVPAPTPVLAPSSTQTM------LPAPVPS-PL-------PSPASTQ---- 1679
Query: 470 EPDALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTG 529
+L AP +A T G
Sbjct: 1680 ------------------------------------------TLALAPALAPT-----LG 1692
Query: 530 LSAPSPTNPFGAGEPGRPTLNQMRTGSPA----------LGLAGGPVGAPLGSMTYSASL 579
S+PS T G G P P Q + +PA L LA GP P +++ + +
Sbjct: 1693 GSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAP 1752
Query: 580 PL----PLSSVPA-GLTL-PASVSVFPQAGAFAPQPLLPTPSSAGPRP 621
PL P+ PA LTL PAS S A AP + S P P
Sbjct: 1753 PLAPASPVGPAPAHTLTLAPASSS----ASLLAPASVQTLTLSPAPVP 1796
Score = 38.1 bits (87), Expect = 0.025
Identities = 86/331 (25%), Positives = 126/331 (38%), Gaps = 45/331 (13%)
Query: 308 VPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWS-------PIPSGTVLSRSQP 360
VP + P S SA P P P + G P P S P P G + S+P
Sbjct: 1041 VPQVLPASLMVSASPAG-PPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRP 1099
Query: 361 WDLTPMLSSSEPWGRTPVL--PAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGG 418
TP LS +P PV PA PP + +L P P P A+ ++ T
Sbjct: 1100 --PTPTLSL-KPTPPAPVRLSPAPPPGSS--SLLKPLTVPPGYTFPPAAATTTSTTTATA 1154
Query: 419 ASTFDPFAKP-PESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLG 477
+T P P P+ ++ LPSG+ S +L P + G+K L
Sbjct: 1155 TTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQ-RPVANAGGSKP---LTFQ 1210
Query: 478 ILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTN 537
I G LT + R + P ++V+L S + ++ + + A +PT
Sbjct: 1211 IQGNKLTLTGAQVRQLAVGQP--RPLQRNVVHLVSAGGQHHLI-SQPAHVALIQAVAPT- 1266
Query: 538 PFGAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVS 597
PG ++ + + +P+ AP G SLPL + VP T+ +
Sbjct: 1267 ------PGPTPVSVLPSSTPST------TPAPTG-----LSLPLAANQVPP--TMVNNTG 1307
Query: 598 VFPQAGAFAPQP-LLPTPSSAGPRPPPPQTG 627
V AP+ L P P A P P PP +G
Sbjct: 1308 VVKIVVRQAPRDGLTPVPPLA-PAPRPPSSG 1337
Score = 35.8 bits (81), Expect = 0.12
Identities = 106/494 (21%), Positives = 180/494 (36%), Gaps = 81/494 (16%)
Query: 135 KDEERLRQERTHALKTKERMALEGIGIGSGQLGFSRRYGE--DYSRSRGSPSSYNSSSSS 192
++EE + ++TH L+ A + I + + + E +++ + G P+ +
Sbjct: 2228 EEEETVASKQTHILEQALCRAEDEEDIRAATQAKAEQVAELAEFNENDGFPAGEGEEAGR 2287
Query: 193 P--------RYTSDLEQARPQTSGEEELQLQLALA----MSREE---AEKPVPPASHRDE 237
P R ++ Q + E ++ A +SREE AE+ V A+ +D
Sbjct: 2288 PGAEDEEMSRAEQEIAALVEQLTPIERYAMKFLEASLEEVSREELKQAEEQVE-AARKDL 2346
Query: 238 DLQLQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQ 297
D + RL ++E E GD S G G ++ + PER + E+L+ ++
Sbjct: 2347 DQAKEEVFRLPQEEEEGP---GAGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGAR 2403
Query: 298 SSILDLADIFV-------PALAPPSTHCSADPWDIPGFRPN-TEASGSSWGPSADPWSPI 349
+ V PP + + P RP T AS + P+ P P+
Sbjct: 2404 AETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPALVP-VPV 2462
Query: 350 PSGTVLSRSQPWDLTP--MLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWG 407
+ +S P + P +L S P + P + P T P A P P+ P
Sbjct: 2463 SAPVPISAPNPITILPVHILPSPPPPSQIPPC-SSPACTPPPACTPP----PAHTPPPAQ 2517
Query: 408 ASLETSDTP----------GGASTFDPFAKPPE------STETKEGLEQALPSGKPSSPV 451
L T +P + T P PE + + E LE A + +S +
Sbjct: 2518 TCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSL 2577
Query: 452 EL----DLFG---DPSPSSKQNGTKEPDA----LDLGILGEALTQPSKEARACRT----P 496
L DL + P S++N + P A L+ G + Q + ++ T P
Sbjct: 2578 SLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLP 2637
Query: 497 ES-------------FLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGE 543
E L PSA+S L ++A + ++ T S+P E
Sbjct: 2638 EGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAE 2697
Query: 544 PGRPTLNQMRTGSP 557
P+ + T SP
Sbjct: 2698 VAAPSTSSSATSSP 2711
Score = 33.9 bits (76), Expect = 0.47
Identities = 39/127 (30%), Positives = 54/127 (42%), Gaps = 18/127 (14%)
Query: 511 DSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGRPTLNQMRTGSPALGLAGGPVGA-- 568
D L P +A P +GL P+ NP RPTL R +P LG A P+
Sbjct: 1319 DGLTPVPPLAPAPRPPSSGL--PAVLNP-------RPTLTPGRLPTPTLGTARAPMPTPT 1369
Query: 569 ---PLGSMTYSASLPLPLSSVP--AGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPRPPP 623
PL + +S S P +S P A LT+ + + V A P +P P+S+ P
Sbjct: 1370 LVRPLLKLVHSPS-PEVSASAPGAAPLTISSPLHVPSSLPGPASSP-MPIPNSSPLASPV 1427
Query: 624 PQTGTNP 630
T + P
Sbjct: 1428 SSTVSVP 1434
Score = 30.4 bits (67), Expect = 5.2
Identities = 55/243 (22%), Positives = 83/243 (34%), Gaps = 36/243 (14%)
Query: 311 LAPPSTHCSADPWDIP-GFRPNTEASGSSWG-PSADPWSPIPSGTVLSRS--QPWDLTPM 366
L PPS SA ++P G RP E + P + + + S S S P DL P+
Sbjct: 2529 LGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPV 2588
Query: 367 LSSSEPWGRT--PVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDP 424
P + P+ P T G+ P G E D+ G +
Sbjct: 2589 AVEILPVSEKNLSLTPSAPSLT------------LEAGSIPNGQEQEAPDSAEGTTL--- 2633
Query: 425 FAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILGEALT 484
T EG E L + S+ +EL P ++ +EP L+ E LT
Sbjct: 2634 -------TVLPEGEELPLCVSE-SNGLEL-----PPSAASDEPLQEP--LEADRTSEELT 2678
Query: 485 QPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEP 544
+ + P+ + ++ S +P+ P SA G G P
Sbjct: 2679 EAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRP 2738
Query: 545 GRP 547
G+P
Sbjct: 2739 GQP 2741
Score = 29.6 bits (65), Expect = 8.8
Identities = 43/198 (21%), Positives = 71/198 (35%), Gaps = 20/198 (10%)
Query: 433 ETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQPSKEARA 492
E K+ EQ + K + ++F P ++ G D G G + SK+A+A
Sbjct: 2331 ELKQAEEQVEAARKDLDQAKEEVFR--LPQEEEEGPGAGDESSCGT-GGGTHRRSKKAKA 2387
Query: 493 CRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGRPTLNQM 552
P + + +A P ++ S T P R + +
Sbjct: 2388 PERPGTRVSERLRG-------ARAETQGANHTPVISAHQTRSTTTP------PRCSPARE 2434
Query: 553 RTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLP 612
R PA P AP A +P+P+S+ P ++ P +++ P +P P
Sbjct: 2435 RVPRPAPRPRPTPASAPAA---IPALVPVPVSA-PVPISAPNPITILPVHILPSPPPPSQ 2490
Query: 613 TPSSAGPRPPPPQTGTNP 630
P + P PP T P
Sbjct: 2491 IPPCSSPACTPPPACTPP 2508
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 47.4 bits (111), Expect = 4e-05
Identities = 99/406 (24%), Positives = 141/406 (34%), Gaps = 89/406 (21%)
Query: 246 RLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQSSILDLAD 305
R + E E+E R+ D S ++ EPE+ E ++ E AD
Sbjct: 1910 RKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYAD 1969
Query: 306 IF-----------VPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTV 354
I+ P PP +A W P A+G + + SPI ++
Sbjct: 1970 IYEQMMLTGLGPACPTREPPLG--AAGDWP-PCLSTKEAAAGRNTSAEKELSSPISPKSL 2026
Query: 355 LSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSD 414
S TP S + G P PP +P G S+E S
Sbjct: 2027 QSD------TPTFSYAALAG-----PTVPPRPEP------------------GPSMEPSL 2057
Query: 415 TPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFGDP----SPSSKQNGTKE 470
TP A PP + +G PS P+ ++ SPS K++G
Sbjct: 2058 TPP--------AVPPRAPILSKG---------PSPPLNGNILSCSPDRRSPSPKESGRSH 2100
Query: 471 PD--ALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLT 528
D D + A QP KEA++ P S + ++ V +P + P
Sbjct: 2101 WDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHV-SPPLDSHLGPARP 2159
Query: 529 GLSAPSPTNPFGAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPA 588
L P+ F + +P P L SPA P AP GS+ +S L L+ P
Sbjct: 2160 SLDFPASAFGFSSLQPAPPQLP-----SPA-----EPRSAPCGSLAFSGDRALALAPGPP 2209
Query: 589 GLTLP---ASVSVFPQAGAFAPQPLLPTPSSAG-------PRPPPP 624
T V+ P + PQ LP+PSS G PRP P
Sbjct: 2210 TRTRHDEYLEVTKAPSLDSSLPQ--LPSPSSPGAPLLSNLPRPASP 2253
Score = 37.4 bits (85), Expect = 0.042
Identities = 86/404 (21%), Positives = 134/404 (33%), Gaps = 79/404 (19%)
Query: 236 DEDLQLQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKT 295
D++ ++ L +R + + +Q + SP G V P +EE+KL
Sbjct: 1735 DDEQEVPLREHATRSPWASDFKDFQ-ESSPQK---GLEVERWLAESPVGLPPEEEDKLTR 1790
Query: 296 SQSSILDLADIFVPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVL 355
S I+ P +PP E G + SPIP ++
Sbjct: 1791 SPFEIIS------PPASPP------------------EMVGQRVPSAPGQESPIPDPKLM 1826
Query: 356 S--RSQP----W--DLTPMLSSSEPWGRTPVLPA-GPPTTDPWALNSPHHKLPSTGADPW 406
+++P W D+ P + P P+ PA GPPT P + + D
Sbjct: 1827 PHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSV 1886
Query: 407 GASLETSDTPGGASTFDPFAKP---PESTETKEGLEQALPSGKPSSPVELDLFGDPSPSS 463
A+++ + P K E +EG +A SS V +S
Sbjct: 1887 VAAVQEGAAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVP--------EAS 1938
Query: 464 KQNGTKEPDALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTR 523
K + T EP+ T+P + R P + P S D +
Sbjct: 1939 KSHATTEPEQ----------TEPEQ-----REPTPY--PDERSFQYADIYEQM------- 1974
Query: 524 NPFLTGLSAPSPT--NPFGAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPL 581
LTGL PT P GA P L+ + A + +P+ + + P
Sbjct: 1975 --MLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPT 2032
Query: 582 PLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPS---SAGPRPP 622
+ AG T+P P P +P + S GP PP
Sbjct: 2033 FSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPP 2076
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 45.8 bits (107), Expect = 1e-04
Identities = 110/509 (21%), Positives = 171/509 (33%), Gaps = 77/509 (15%)
Query: 169 SRRYGEDYSRSRGSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEA--E 226
S E++S S SS +SSSSS T ++ ++ ELQ +L + +++ +
Sbjct: 110 SEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKK 169
Query: 227 KPVPPASHRDE--------DLQLQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQR 278
KP P DE D ++ + Q ++ P+ +
Sbjct: 170 KPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDT 229
Query: 279 DREPEREERKE-----EEKLKTSQSSILDLADIFVPALAPPSTHCSAD----PWDIPGFR 329
+E KE +E T++ + D + A S ++ P +
Sbjct: 230 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 289
Query: 330 PNTEASGSSWGP-----------------SADPWSPIPSGTVLSRSQPWDLTPMLSSSEP 372
P +A ++ GP S P P P+ + + P + P + S P
Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 349
Query: 373 WGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDT-PGGASTFDPFAKPPES 431
TP PA P TT A +P P+T +P + +++ T P + P K P
Sbjct: 350 --TTPKEPA-PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP--KKPAP 404
Query: 432 TETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQPSKEAR 491
T KE P++P E P+P++K+ P A T P K A
Sbjct: 405 TTPKEPAPTTPKEPTPTTPKE------PAPTTKEPAPTTPKE-------PAPTAPKKPAP 451
Query: 492 ACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTN----PFGAGEPGRP 547
TP+ P+ ++ K P T+ P T P+PT P EP
Sbjct: 452 T--TPKE---PAPTT-------PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 499
Query: 548 TLNQMRTG----SPALGLAGGPVGA--PLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQ 601
T T SP P P + + P P PA +
Sbjct: 500 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 559
Query: 602 AGAFAPQPLLPTPSSAGPRPPPPQTGTNP 630
A +P TP P P T T P
Sbjct: 560 APTTPKEPAPTTPKETAPTTPKKLTPTTP 588
Score = 40.8 bits (94), Expect = 0.004
Identities = 44/165 (26%), Positives = 61/165 (36%), Gaps = 15/165 (9%)
Query: 313 PPSTHCSADPWDIP-GFRPNTEASGSSWGPSADPWSPIPSGTV-LSRSQPWDLTPMLSSS 370
P ST C P G P T + P +P P GT + +P TP
Sbjct: 700 PTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK-EPAPTTPKGTAPTTLKEPAPTTP--KKP 756
Query: 371 EPWGRTPVLPAGPPTT--DPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKP 428
P P GP +T D A +P P+T +P TP + P P
Sbjct: 757 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP------APTTPKKPAPTTPETPP 810
Query: 429 PESTETKEGLEQALPSGKPSSPVEL--DLFGDPSPSSKQNGTKEP 471
P ++E P+ SP E +L +P+P + +N KEP
Sbjct: 811 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 855
Score = 31.6 bits (70), Expect = 2.3
Identities = 35/116 (30%), Positives = 45/116 (38%), Gaps = 19/116 (16%)
Query: 332 TEASGSSWGPSADPWSPIPSGTV-LSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTT---- 386
T G + S P P T + +P TP +P TP P PPTT
Sbjct: 764 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP----KKPAPTTPETP--PPTTSEVS 817
Query: 387 ------DPWALN-SPHHKLPSTGADPWGASLETS-DTPGGASTFDPFAKPPESTET 434
+P ++ SP P A+P +LE S PG +T P A PE T T
Sbjct: 818 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 873
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 45.8 bits (107), Expect = 1e-04
Identities = 110/509 (21%), Positives = 171/509 (33%), Gaps = 77/509 (15%)
Query: 169 SRRYGEDYSRSRGSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEA--E 226
S E++S S SS +SSSSS T ++ ++ ELQ +L + +++ +
Sbjct: 151 SEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKK 210
Query: 227 KPVPPASHRDE--------DLQLQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQR 278
KP P DE D ++ + Q ++ P+ +
Sbjct: 211 KPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDT 270
Query: 279 DREPEREERKE-----EEKLKTSQSSILDLADIFVPALAPPSTHCSAD----PWDIPGFR 329
+E KE +E T++ + D + A S ++ P +
Sbjct: 271 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 330
Query: 330 PNTEASGSSWGP-----------------SADPWSPIPSGTVLSRSQPWDLTPMLSSSEP 372
P +A ++ GP S P P P+ + + P + P + S P
Sbjct: 331 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 390
Query: 373 WGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDT-PGGASTFDPFAKPPES 431
TP PA P TT A +P P+T +P + +++ T P + P K P
Sbjct: 391 --TTPKEPA-PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP--KKPAP 445
Query: 432 TETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQPSKEAR 491
T KE P++P E P+P++K+ P A T P K A
Sbjct: 446 TTPKEPAPTTPKEPTPTTPKE------PAPTTKEPAPTTPKE-------PAPTAPKKPAP 492
Query: 492 ACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTN----PFGAGEPGRP 547
TP+ P+ ++ K P T+ P T P+PT P EP
Sbjct: 493 T--TPKE---PAPTT-------PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 540
Query: 548 TLNQMRTG----SPALGLAGGPVGA--PLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQ 601
T T SP P P + + P P PA +
Sbjct: 541 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 600
Query: 602 AGAFAPQPLLPTPSSAGPRPPPPQTGTNP 630
A +P TP P P T T P
Sbjct: 601 APTTPKEPAPTTPKETAPTTPKKLTPTTP 629
Score = 40.8 bits (94), Expect = 0.004
Identities = 44/165 (26%), Positives = 61/165 (36%), Gaps = 15/165 (9%)
Query: 313 PPSTHCSADPWDIP-GFRPNTEASGSSWGPSADPWSPIPSGTV-LSRSQPWDLTPMLSSS 370
P ST C P G P T + P +P P GT + +P TP
Sbjct: 741 PTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK-EPAPTTPKGTAPTTLKEPAPTTP--KKP 797
Query: 371 EPWGRTPVLPAGPPTT--DPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKP 428
P P GP +T D A +P P+T +P TP + P P
Sbjct: 798 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP------APTTPKKPAPTTPETPP 851
Query: 429 PESTETKEGLEQALPSGKPSSPVEL--DLFGDPSPSSKQNGTKEP 471
P ++E P+ SP E +L +P+P + +N KEP
Sbjct: 852 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 896
Score = 31.6 bits (70), Expect = 2.3
Identities = 35/116 (30%), Positives = 45/116 (38%), Gaps = 19/116 (16%)
Query: 332 TEASGSSWGPSADPWSPIPSGTV-LSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTT---- 386
T G + S P P T + +P TP +P TP P PPTT
Sbjct: 805 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP----KKPAPTTPETP--PPTTSEVS 858
Query: 387 ------DPWALN-SPHHKLPSTGADPWGASLETS-DTPGGASTFDPFAKPPESTET 434
+P ++ SP P A+P +LE S PG +T P A PE T T
Sbjct: 859 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 914
>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c2 isoform a [Homo sapiens]
Length = 1214
Score = 45.8 bits (107), Expect = 1e-04
Identities = 74/264 (28%), Positives = 101/264 (38%), Gaps = 28/264 (10%)
Query: 372 PWGRTPVLP---AGPPTTDPWALNSPHHKLPS---TGADPWGASLETSDTPGGA-STFDP 424
P G P+ P AGPP A+ +P +P+ +GA P SL S+ G A ST P
Sbjct: 966 PPGSQPIPPTGAAGPPAVHGLAV-APASVVPAPAGSGAPP--GSLGPSEQIGQAGSTAGP 1022
Query: 425 FAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILGEA-L 483
+ P + +P P P +P S G P + G+ G A L
Sbjct: 1023 QQQQPAGAPQPGAVPPGVPPPGPHGPSPFP--NQQTPPSMMPGAV-PGSGHPGVAGNAPL 1079
Query: 484 TQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRN---PFLTGLSAPSPTNPFG 540
P P + P S ++ + AP + PF G + P P P
Sbjct: 1080 GLPFGMPPPPPPPAPSIIPFGSLADSISINLPAPPNLHGHHHHLPFAPG-TLPPPNLPVS 1138
Query: 541 AGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFP 600
P P L T +L P+G LGS +A P +++V L LP S S P
Sbjct: 1139 MANPLHPNLPATTTMPSSL-----PLGPGLGSA--AAQSPAIVAAVQGNL-LP-SASPLP 1189
Query: 601 QAGA-FAPQPLLPTPSSAGPRPPP 623
G P P P+P + P PPP
Sbjct: 1190 DPGTPLPPDPTAPSPGTVTPVPPP 1213
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 45.4 bits (106), Expect = 2e-04
Identities = 73/300 (24%), Positives = 102/300 (34%), Gaps = 41/300 (13%)
Query: 342 SADPWSPIPSGTVLSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPST 401
S P P P+ + + P + P + S P TP PA P TT A +P P+T
Sbjct: 226 STTPKEPTPTTIKSAPTTPKEPAPTTTKSAP--TTPKEPA-PTTTKEPAPTTPKEPAPTT 282
Query: 402 GADPWGASLETSDT-PGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPS 460
+P + +++ T P + P K P T KE P++P E P+
Sbjct: 283 TKEPAPTTTKSAPTTPKEPAPTTP--KKPAPTTPKEPAPTTPKEPTPTTPKE------PA 334
Query: 461 PSSKQNGTKEPDALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVA 520
P++K+ P A T P K A TP+ P+ ++ K P
Sbjct: 335 PTTKEPAPTTPKE-------PAPTAPKKPAPT--TPKE---PAPTT-------PKEPAPT 375
Query: 521 KTRNPFLTGLSAPSPTN----PFGAGEPGRPTLNQMRTG----SPALGLAGGPVGA--PL 570
T+ P T P+PT P EP T T SP P P
Sbjct: 376 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 435
Query: 571 GSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPRPPPPQTGTNP 630
+ + P P PA + A +P TP P P T T P
Sbjct: 436 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 495
Score = 44.7 bits (104), Expect = 3e-04
Identities = 75/308 (24%), Positives = 103/308 (33%), Gaps = 54/308 (17%)
Query: 329 RPNTEASGSSWGPS-ADPWSPIPSGTVLSRSQ-PWDLTPMLSSSEPWGRTPVLPAGPPTT 386
+P +A ++ GP+ P P P+ S P + TP S P TP PA PTT
Sbjct: 196 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP--TTPKEPA--PTT 251
Query: 387 DPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGK 446
A +P P+T +P TP K P T TKE S
Sbjct: 252 TKSAPTTPKEPAPTTTKEP------APTTP----------KEPAPTTTKEPAPTTTKSA- 294
Query: 447 PSSPVELDLFGDPSPSSKQNGT----KEPDALDLGILGEALTQPSKEARACRTPESFLGP 502
P++P E P+P++ + KEP A T P + TP + P
Sbjct: 295 PTTPKE------PAPTTPKKPAPTTPKEP----------APTTPKEP-----TPTTPKEP 333
Query: 503 SASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGRPTLNQMRTGSPALGLA 562
+ ++ + K P + P T P+PT P EP T + SP
Sbjct: 334 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP---KEPAPTTTKEP---SPTTPKE 387
Query: 563 GGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPRPP 622
P T P S P P+ + A +P TP P P
Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 447
Query: 623 PPQTGTNP 630
T P
Sbjct: 448 KEPAPTTP 455
Score = 40.8 bits (94), Expect = 0.004
Identities = 44/165 (26%), Positives = 61/165 (36%), Gaps = 15/165 (9%)
Query: 313 PPSTHCSADPWDIP-GFRPNTEASGSSWGPSADPWSPIPSGTV-LSRSQPWDLTPMLSSS 370
P ST C P G P T + P +P P GT + +P TP
Sbjct: 607 PTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK-EPAPTTPKGTAPTTLKEPAPTTP--KKP 663
Query: 371 EPWGRTPVLPAGPPTT--DPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKP 428
P P GP +T D A +P P+T +P TP + P P
Sbjct: 664 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP------APTTPKKPAPTTPETPP 717
Query: 429 PESTETKEGLEQALPSGKPSSPVEL--DLFGDPSPSSKQNGTKEP 471
P ++E P+ SP E +L +P+P + +N KEP
Sbjct: 718 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 762
Score = 31.6 bits (70), Expect = 2.3
Identities = 35/116 (30%), Positives = 45/116 (38%), Gaps = 19/116 (16%)
Query: 332 TEASGSSWGPSADPWSPIPSGTV-LSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTT---- 386
T G + S P P T + +P TP +P TP P PPTT
Sbjct: 671 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP----KKPAPTTPETP--PPTTSEVS 724
Query: 387 ------DPWALN-SPHHKLPSTGADPWGASLETS-DTPGGASTFDPFAKPPESTET 434
+P ++ SP P A+P +LE S PG +T P A PE T T
Sbjct: 725 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 780
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 45.4 bits (106), Expect = 2e-04
Identities = 73/300 (24%), Positives = 102/300 (34%), Gaps = 41/300 (13%)
Query: 342 SADPWSPIPSGTVLSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPST 401
S P P P+ + + P + P + S P TP PA P TT A +P P+T
Sbjct: 267 STTPKEPTPTTIKSAPTTPKEPAPTTTKSAP--TTPKEPA-PTTTKEPAPTTPKEPAPTT 323
Query: 402 GADPWGASLETSDT-PGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPS 460
+P + +++ T P + P K P T KE P++P E P+
Sbjct: 324 TKEPAPTTTKSAPTTPKEPAPTTP--KKPAPTTPKEPAPTTPKEPTPTTPKE------PA 375
Query: 461 PSSKQNGTKEPDALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVA 520
P++K+ P A T P K A TP+ P+ ++ K P
Sbjct: 376 PTTKEPAPTTPKE-------PAPTAPKKPAPT--TPKE---PAPTT-------PKEPAPT 416
Query: 521 KTRNPFLTGLSAPSPTN----PFGAGEPGRPTLNQMRTG----SPALGLAGGPVGA--PL 570
T+ P T P+PT P EP T T SP P P
Sbjct: 417 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 476
Query: 571 GSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPRPPPPQTGTNP 630
+ + P P PA + A +P TP P P T T P
Sbjct: 477 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 536
Score = 44.7 bits (104), Expect = 3e-04
Identities = 75/308 (24%), Positives = 103/308 (33%), Gaps = 54/308 (17%)
Query: 329 RPNTEASGSSWGPS-ADPWSPIPSGTVLSRSQ-PWDLTPMLSSSEPWGRTPVLPAGPPTT 386
+P +A ++ GP+ P P P+ S P + TP S P TP PA PTT
Sbjct: 237 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP--TTPKEPA--PTT 292
Query: 387 DPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGK 446
A +P P+T +P TP K P T TKE S
Sbjct: 293 TKSAPTTPKEPAPTTTKEP------APTTP----------KEPAPTTTKEPAPTTTKSA- 335
Query: 447 PSSPVELDLFGDPSPSSKQNGT----KEPDALDLGILGEALTQPSKEARACRTPESFLGP 502
P++P E P+P++ + KEP A T P + TP + P
Sbjct: 336 PTTPKE------PAPTTPKKPAPTTPKEP----------APTTPKEP-----TPTTPKEP 374
Query: 503 SASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGRPTLNQMRTGSPALGLA 562
+ ++ + K P + P T P+PT P EP T + SP
Sbjct: 375 APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP---KEPAPTTTKEP---SPTTPKE 428
Query: 563 GGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPRPP 622
P T P S P P+ + A +P TP P P
Sbjct: 429 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 488
Query: 623 PPQTGTNP 630
T P
Sbjct: 489 KEPAPTTP 496
Score = 40.8 bits (94), Expect = 0.004
Identities = 44/165 (26%), Positives = 61/165 (36%), Gaps = 15/165 (9%)
Query: 313 PPSTHCSADPWDIP-GFRPNTEASGSSWGPSADPWSPIPSGTV-LSRSQPWDLTPMLSSS 370
P ST C P G P T + P +P P GT + +P TP
Sbjct: 648 PTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK-EPAPTTPKGTAPTTLKEPAPTTP--KKP 704
Query: 371 EPWGRTPVLPAGPPTT--DPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKP 428
P P GP +T D A +P P+T +P TP + P P
Sbjct: 705 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP------APTTPKKPAPTTPETPP 758
Query: 429 PESTETKEGLEQALPSGKPSSPVEL--DLFGDPSPSSKQNGTKEP 471
P ++E P+ SP E +L +P+P + +N KEP
Sbjct: 759 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 803
Score = 31.6 bits (70), Expect = 2.3
Identities = 35/116 (30%), Positives = 45/116 (38%), Gaps = 19/116 (16%)
Query: 332 TEASGSSWGPSADPWSPIPSGTV-LSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTT---- 386
T G + S P P T + +P TP +P TP P PPTT
Sbjct: 712 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP----KKPAPTTPETP--PPTTSEVS 765
Query: 387 ------DPWALN-SPHHKLPSTGADPWGASLETS-DTPGGASTFDPFAKPPESTET 434
+P ++ SP P A+P +LE S PG +T P A PE T T
Sbjct: 766 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 821
>gi|223972704 hypothetical protein LOC284418 [Homo sapiens]
Length = 922
Score = 45.1 bits (105), Expect = 2e-04
Identities = 71/276 (25%), Positives = 101/276 (36%), Gaps = 52/276 (18%)
Query: 288 KEEEKLKTSQSSILDLADIFVPALAP-PSTHCSADPWD-IPGFRPNTEASGSSWGPSADP 345
++ E L S S L A LAP P C + P+ IP R GS GP P
Sbjct: 342 QDTEDLMDSGGSTLSSA---ASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPP 398
Query: 346 WSPIPSGTVLSRSQP----------------WDLTPML-------SSSEPWGRTPVLPAG 382
PSG V S P W P L ++S P + P +PA
Sbjct: 399 CQKAPSGLVTSCKAPFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPA- 457
Query: 383 PPTTDPWALNSPHHKLPSTGADPWGAS-LETSDTPGGASTFDPFAKPPESTET------- 434
P+ A+ +P K P+ A AS S A P PP S +
Sbjct: 458 -PSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIP 516
Query: 435 ----------KEGLEQALPSGK--PSSPVELDLFGDPSPSSKQNGTKEPDALDLGILGEA 482
K+ L PS K P+SP E + P P+S+ + D L GI G A
Sbjct: 517 QKAVSPTAPKKKSLLLPAPSQKALPTSPTEYQMALSP-PASRGKLPGDFDVLPTGIPGRA 575
Query: 483 LTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQ 518
+ + S ++ P + + +V + + K+P+
Sbjct: 576 VLERS-QSGGKPEPVVTVRTQETDVVEMTTQAKSPE 610
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,571,706
Number of Sequences: 37866
Number of extensions: 1906767
Number of successful extensions: 12328
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 713
Number of HSP's that attempted gapping in prelim test: 9804
Number of HSP's gapped (non-prelim): 2669
length of query: 632
length of database: 18,247,518
effective HSP length: 108
effective length of query: 524
effective length of database: 14,157,990
effective search space: 7418786760
effective search space used: 7418786760
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.