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Search of human proteins with 157388910
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157388910 TIMELESS interacting protein [Homo sapiens]
(301 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157388910 TIMELESS interacting protein [Homo sapiens] 608 e-174
gi|4504063 golgin 97 [Homo sapiens] 38 0.010
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 37 0.016
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 37 0.016
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 37 0.016
gi|31982906 cingulin-like 1 [Homo sapiens] 37 0.028
gi|20806097 nucleolar complex associated 3 homolog [Homo sapiens] 37 0.028
gi|40255119 RAS and EF-hand domain containing [Homo sapiens] 36 0.036
gi|221219020 NYD-SP11 protein [Homo sapiens] 36 0.048
gi|21071060 SWI/SNF-related matrix-associated actin-dependent re... 35 0.062
gi|187761314 SWI/SNF-related matrix-associated actin-dependent r... 35 0.062
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 34 0.14
gi|116268095 spermatid maturation 1 [Homo sapiens] 34 0.14
gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [H... 34 0.18
gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens] 34 0.18
gi|22749429 coiled-coil domain containing 89 [Homo sapiens] 34 0.18
gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Hom... 33 0.24
gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo ... 33 0.24
gi|58530845 zyxin [Homo sapiens] 33 0.24
gi|4508047 zyxin [Homo sapiens] 33 0.24
gi|126723390 ankyrin repeat domain 24 [Homo sapiens] 33 0.24
gi|18079216 CASK interacting protein 1 [Homo sapiens] 33 0.31
gi|116875767 tight junction protein 1 isoform a [Homo sapiens] 33 0.31
gi|4557365 Bloom syndrome protein [Homo sapiens] 32 0.53
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 32 0.53
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 32 0.53
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 32 0.53
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 32 0.69
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap... 32 0.69
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens] 32 0.69
>gi|157388910 TIMELESS interacting protein [Homo sapiens]
Length = 301
Score = 608 bits (1567), Expect = e-174
Identities = 301/301 (100%), Positives = 301/301 (100%)
Query: 1 MLEPQENGVIDLPDYEHVEDETFPPFPPPASPERQDGEGTEPDEESGNGAPVPVPPKRTV 60
MLEPQENGVIDLPDYEHVEDETFPPFPPPASPERQDGEGTEPDEESGNGAPVPVPPKRTV
Sbjct: 1 MLEPQENGVIDLPDYEHVEDETFPPFPPPASPERQDGEGTEPDEESGNGAPVPVPPKRTV 60
Query: 61 KRNIPKLDAQRLISERGLPALRHVFDKAKFKGKGHEAEDLKMLIRHMEHWAHRLFPKLQF 120
KRNIPKLDAQRLISERGLPALRHVFDKAKFKGKGHEAEDLKMLIRHMEHWAHRLFPKLQF
Sbjct: 61 KRNIPKLDAQRLISERGLPALRHVFDKAKFKGKGHEAEDLKMLIRHMEHWAHRLFPKLQF 120
Query: 121 EDFIDRVEYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTN 180
EDFIDRVEYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTN
Sbjct: 121 EDFIDRVEYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTN 180
Query: 181 LSESEMFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVE 240
LSESEMFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVE
Sbjct: 181 LSESEMFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVE 240
Query: 241 EVNTDEDQKEESNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEA 300
EVNTDEDQKEESNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEA
Sbjct: 241 EVNTDEDQKEESNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEA 300
Query: 301 R 301
R
Sbjct: 301 R 301
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 38.1 bits (87), Expect = 0.010
Identities = 49/215 (22%), Positives = 95/215 (44%), Gaps = 21/215 (9%)
Query: 96 EAEDLKMLIRHMEHWAHRLFPKLQFEDFIDRVEYLGSKK--EVQTCLKRIRLDLPILHED 153
E L ++ M++ + LF Q D +D +E ++ +++ L + L + ++
Sbjct: 145 EKNILTAQLQEMKNQSMNLF---QRRDEMDELEGFQQQELSKIKHMLLKKEESLGKMEQE 201
Query: 154 FVSNNDEVAENNEHDVTSTELDPFLTNLSESEMFASELSR--SLTEEQQQRI------ER 205
+ E++ E + S ++ L+ E EL R S EEQ+ +
Sbjct: 202 LEARTRELSRTQEELMNSNQMSSDLSQKLE------ELQRHYSTLEEQRDHVIASKTGAE 255
Query: 206 NKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVEEVNTDEDQKEESNGLNEDILDNPCN 265
+K ALE+++ +L + Q L D+ T E+V T +K S L + + N
Sbjct: 256 SKITALEQKEQELQALIQQLSIDLQKVTAETQEKEDVITHLQEKVAS--LEKRLEQNLSG 313
Query: 266 DAIANTLNEEETLLDQSFKNVQQQLDATSRNITEA 300
+ L +E+TL +Q+ ++ +QQL A + +A
Sbjct: 314 EEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKA 348
Score = 32.3 bits (72), Expect = 0.53
Identities = 48/208 (23%), Positives = 82/208 (39%), Gaps = 29/208 (13%)
Query: 97 AEDLKMLIRHM----EHWAHRLFPKLQFEDFIDRVEYLGSKKEVQTCLKRIRLDLPILHE 152
++ L+ L RH E H + K E I +E ++E+Q ++++ +DL +
Sbjct: 227 SQKLEELQRHYSTLEEQRDHVIASKTGAESKITALEQ--KEQELQALIQQLSIDLQKVTA 284
Query: 153 DFVSNNDEVAENNEHDVTSTELDPFLTNLSESEMFASELSRSLTEEQQQRIERNKQLALE 212
+ ++V + + V S E NLS E L EQ R + LA
Sbjct: 285 E-TQEKEDVITHLQEKVASLE-KRLEQNLSGEEHVQELLKEKTLAEQNLEDTRQQLLAAR 342
Query: 213 RRQAKLLSNSQTLGNDMLMNTPRAHTVEE-VNTDEDQKEESNGLNEDILDNPCNDAIANT 271
QAK ++ +T R +E+ + E+Q ++S G+ A T
Sbjct: 343 SSQAKAINTLET----------RVRELEQTLQASEEQLQQSKGI----------VAAQET 382
Query: 272 LNEEETLLDQSFKNVQQQLDATSRNITE 299
+E +Q +VQQQ A + E
Sbjct: 383 QIQELAAANQESSHVQQQALALEQQFLE 410
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 37.4 bits (85), Expect = 0.016
Identities = 37/147 (25%), Positives = 61/147 (41%), Gaps = 19/147 (12%)
Query: 152 EDFVSNNDEVAENNEHDVTSTELDPFL---------TNLSESEMFASELSRSLTEEQQQR 202
E+ + +E E E D S+E+ T E E+ E ++EEQ+Q
Sbjct: 1227 EEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQS 1286
Query: 203 IERNKQLALERRQAKLLSNSQTLGN---------DMLMNTPRAHTVEEVNTDEDQKEESN 253
E ++L + + + ++T N D + + + +EE T ED KEE
Sbjct: 1287 EEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEP- 1345
Query: 254 GLNEDILDNPCNDAIANTLNEEETLLD 280
G+ E LD + ++EET LD
Sbjct: 1346 GVQESFLDANMQKSREKIKDKEETELD 1372
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 37.4 bits (85), Expect = 0.016
Identities = 37/147 (25%), Positives = 61/147 (41%), Gaps = 19/147 (12%)
Query: 152 EDFVSNNDEVAENNEHDVTSTELDPFL---------TNLSESEMFASELSRSLTEEQQQR 202
E+ + +E E E D S+E+ T E E+ E ++EEQ+Q
Sbjct: 1227 EEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQS 1286
Query: 203 IERNKQLALERRQAKLLSNSQTLGN---------DMLMNTPRAHTVEEVNTDEDQKEESN 253
E ++L + + + ++T N D + + + +EE T ED KEE
Sbjct: 1287 EEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEP- 1345
Query: 254 GLNEDILDNPCNDAIANTLNEEETLLD 280
G+ E LD + ++EET LD
Sbjct: 1346 GVQESFLDANMQKSREKIKDKEETELD 1372
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 37.4 bits (85), Expect = 0.016
Identities = 37/147 (25%), Positives = 61/147 (41%), Gaps = 19/147 (12%)
Query: 152 EDFVSNNDEVAENNEHDVTSTELDPFL---------TNLSESEMFASELSRSLTEEQQQR 202
E+ + +E E E D S+E+ T E E+ E ++EEQ+Q
Sbjct: 1227 EEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQS 1286
Query: 203 IERNKQLALERRQAKLLSNSQTLGN---------DMLMNTPRAHTVEEVNTDEDQKEESN 253
E ++L + + + ++T N D + + + +EE T ED KEE
Sbjct: 1287 EEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEP- 1345
Query: 254 GLNEDILDNPCNDAIANTLNEEETLLD 280
G+ E LD + ++EET LD
Sbjct: 1346 GVQESFLDANMQKSREKIKDKEETELD 1372
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 36.6 bits (83), Expect = 0.028
Identities = 41/183 (22%), Positives = 78/183 (42%), Gaps = 14/183 (7%)
Query: 131 GSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAEN-NEHDVTSTELDPFLTNLSESEMFAS 189
G + + + LK+ ++ L E V E E + EL+ NLS++
Sbjct: 857 GDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQK 916
Query: 190 ELSRSLTEEQQQRIE-RNKQLALERRQAKLLSNSQTLGNDM--LMNTPRAHTVEEVNTDE 246
+LS L EE +Q+ + R + +E + L + L +M ++ R T+E N +
Sbjct: 917 QLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLD 976
Query: 247 DQKEES--------NGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLD--ATSRN 296
+ KE++ L E L+ + A + +E L+++ ++ Q+ D T R
Sbjct: 977 EYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQ 1036
Query: 297 ITE 299
+ E
Sbjct: 1037 LLE 1039
>gi|20806097 nucleolar complex associated 3 homolog [Homo sapiens]
Length = 800
Score = 36.6 bits (83), Expect = 0.028
Identities = 32/116 (27%), Positives = 57/116 (49%), Gaps = 10/116 (8%)
Query: 177 FLT-NLSESE-MFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTP 234
FLT +LS SE + A + ++ ++I R Q A E+ LL G ++
Sbjct: 109 FLTRDLSSSEPVHAKKRKHERIIDKYEKIPRTLQTAPEKELIHLLPIKDKSG---IIPQT 165
Query: 235 RAHTVEEVNTDEDQKEESNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQL 290
R V + N DE+ +EE L E+I+++P + L EE L+++ K ++++
Sbjct: 166 REKPVTDSNKDEEDQEEERELEEEIIEDPIQE-----LTIEEHLIERKKKLQEKKM 216
>gi|40255119 RAS and EF-hand domain containing [Homo sapiens]
Length = 740
Score = 36.2 bits (82), Expect = 0.036
Identities = 43/178 (24%), Positives = 80/178 (44%), Gaps = 18/178 (10%)
Query: 125 DRVEYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAEN--NEHDVTSTELDPFLTNLS 182
D +++ +++V T + I L P L + + + V +N E + STE++ +
Sbjct: 137 DEAKFIPREEQVSTLYQNINLVEPRLIQPY----EHVIKNFIREIRLQSTEMENLAIAVK 192
Query: 183 ESEMFASELSRSLTEEQQQRIE--RNKQLALERRQAK-----LLSNSQTLGNDMLMNTPR 235
++ A+ L EE QRI+ +K E+R+A+ L +T D+ + +
Sbjct: 193 RAQDKAAMQLSELEEEMDQRIQAAEHKTRKDEKRKAEEALSDLRRQYETEVGDLQVTIKK 252
Query: 236 AHTVEEVNTDEDQKEESNGLNEDILD-NPCNDAIANTLNEEETLLDQSFKNVQQQLDA 292
+EE + QKE+ L + I D + N + L E +T + +Q +LDA
Sbjct: 253 LRKLEEQSKRVSQKEDVAALKKQIYDLSMENQKVKKDLLEAQT----NIAFLQSELDA 306
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 35.8 bits (81), Expect = 0.048
Identities = 31/126 (24%), Positives = 57/126 (45%), Gaps = 6/126 (4%)
Query: 152 EDFVSNNDEVAENNEHDVTSTELDPFLTNLSESEMFASELSRSLTEEQQQRIERNKQLAL 211
E F S DEV E+ EH S E++ L L + E +SE EE+++ E ++
Sbjct: 2211 EKFSSQVDEV-ESEEH--FSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEE 2267
Query: 212 ERRQAKLLSNSQTLGNDMLMNTPRAHTVEEVNTDEDQKEESNGLNEDILDNPCNDAIANT 271
ER++ + Q + + E+ + +KEE E+I+ +++++
Sbjct: 2268 ERKEEEEGEEKQVEKEE---EEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDE 2324
Query: 272 LNEEET 277
EEE+
Sbjct: 2325 EEEEES 2330
>gi|21071060 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a-like 1 [Homo sapiens]
Length = 954
Score = 35.4 bits (80), Expect = 0.062
Identities = 17/30 (56%), Positives = 23/30 (76%)
Query: 191 LSRSLTEEQQQRIERNKQLALERRQAKLLS 220
+S LTEEQ+++IE N+Q AL RR KLL+
Sbjct: 1 MSLPLTEEQRKKIEENRQKALARRAEKLLA 30
>gi|187761314 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a-like 1 [Homo sapiens]
Length = 954
Score = 35.4 bits (80), Expect = 0.062
Identities = 17/30 (56%), Positives = 23/30 (76%)
Query: 191 LSRSLTEEQQQRIERNKQLALERRQAKLLS 220
+S LTEEQ+++IE N+Q AL RR KLL+
Sbjct: 1 MSLPLTEEQRKKIEENRQKALARRAEKLLA 30
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 34.3 bits (77), Expect = 0.14
Identities = 37/160 (23%), Positives = 73/160 (45%), Gaps = 23/160 (14%)
Query: 157 NNDEVAENNEHDVTSTELDPFLTNLSESEMFASEL---------SRSLTEEQQQRIERNK 207
N D++ + E D+ + DP L + MF EL ++ ++ E +++ + NK
Sbjct: 2744 NLDDLLRSGEFDIIAYT-DPELDMGDKKSMFNEELDLPIDDKLDNQCVSVEPKKKEQENK 2802
Query: 208 QLALERRQAKLLSNSQTLGNDMLMNTPRAHTVEEVNTDEDQKEESNGLNEDILDNPCNDA 267
L L + + T+ N++ ++ E + ++ +E N+D +D PC+ A
Sbjct: 2803 TLVLSDKHSP--QKKSTVTNEVKTEVLSPNSKVESKCETEKNDE----NKDNVDTPCSQA 2856
Query: 268 IANT-LNE-EETLL-----DQSFKNVQQQLDATSRNITEA 300
A++ LN+ E+T L D K ++ S N+ +A
Sbjct: 2857 SAHSDLNDGEKTSLHPCDPDLFEKRTNRETAGPSANVIQA 2896
>gi|116268095 spermatid maturation 1 [Homo sapiens]
Length = 309
Score = 34.3 bits (77), Expect = 0.14
Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 4/37 (10%)
Query: 23 FPPFPPPASPE----RQDGEGTEPDEESGNGAPVPVP 55
+P PPP SPE + GEG P+ E+ PVP P
Sbjct: 205 YPVNPPPPSPEAPSHKNGGEGAVPEAEAAQYQPVPAP 241
>gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [Homo
sapiens]
Length = 1447
Score = 33.9 bits (76), Expect = 0.18
Identities = 27/107 (25%), Positives = 51/107 (47%), Gaps = 5/107 (4%)
Query: 156 SNNDEVAENNEHDVTSTELDPFLTNLSESEMFASELSRSLTEEQQQRIERNKQLALERRQ 215
S+ + +EN ++ ++S +S++ SEL + ++ E+ ++L ++
Sbjct: 1176 SSEMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDL- 1234
Query: 216 AKLLSNSQTLGNDMLMNTPRAHTVEEVNTDEDQKEESNGLNEDILDN 262
KL+ + G+ + R HT E +DE Q E L EDIL+N
Sbjct: 1235 TKLVQEQKPKGSQR--SRKRGHTASE--SDEQQWPEEKRLKEDILEN 1277
>gi|30260188 Golgi autoantigen, golgin subfamily a, 5 [Homo sapiens]
Length = 731
Score = 33.9 bits (76), Expect = 0.18
Identities = 37/175 (21%), Positives = 74/175 (42%), Gaps = 17/175 (9%)
Query: 119 QFEDFIDRVE-YLGSKKEVQTCLKRIRLDLPILHED-FVSNNDEVAENNEHDVTSTELDP 176
Q +D D++ SK+E++T L+R++ + + ED + + N + + D +L
Sbjct: 513 QLQDLHDQIAGQKASKQELETELERLKQEFHYIEEDLYRTKNTLQSRIKDRDEEIQKLRN 572
Query: 177 FLTNLSESEMFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRA 236
LTN + S SEL L + + I++ +L + T N ++ R
Sbjct: 573 QLTNKTLSNSSQSELENRLHQLTETLIQKQ----------TMLESLSTEKNSLVFQLERL 622
Query: 237 HTVEEVNTDEDQKEESNGLNEDILDNPCNDAIANT---LNEEETLLDQSFKNVQQ 288
+++N+ + +N +DN + N N+ ET L + V++
Sbjct: 623 E--QQMNSASGSSSNGSSINMSGIDNGEGTRLRNVPVLFNDTETNLAGMYGKVRK 675
>gi|22749429 coiled-coil domain containing 89 [Homo sapiens]
Length = 374
Score = 33.9 bits (76), Expect = 0.18
Identities = 34/126 (26%), Positives = 53/126 (42%), Gaps = 11/126 (8%)
Query: 144 RLDLPILHEDFVSNNDEVAENNEHDVTSTELDPF------LTNLSESEMFASELSRSLTE 197
R+D P E N+++ N E + ELD L LSE E + RS E
Sbjct: 13 RMDTPPPEERLEKQNEKL-NNQEEETEFKELDGLREALANLRGLSEEERSEKAMLRSRIE 71
Query: 198 EQQQRI---ERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVEEVNTDEDQKEESNG 254
EQ Q I +R ALER Q L N++ L M+ + E + +++ +
Sbjct: 72 EQSQLICILKRRSDEALERCQILELLNAE-LEEKMMQEAEKLKAQGEYSRKLEERFMTLA 130
Query: 255 LNEDIL 260
N +++
Sbjct: 131 ANHELM 136
>gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Homo
sapiens]
Length = 1134
Score = 33.5 bits (75), Expect = 0.24
Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 16/70 (22%)
Query: 13 PDYEHVED---ETFPPFPPPASPERQDGEGTEPDEESGNGAP------VPVPP-KRTVKR 62
P+ HV D E +PP+PPP P GE P E+S + P V +PP KRT
Sbjct: 859 PEAPHVLDVYLEEYPPYPPPPYPS---GEPEGPGEDSVSMRPPEITGQVSLPPGKRT--- 912
Query: 63 NIPKLDAQRL 72
N+ K ++R+
Sbjct: 913 NLRKTGSERI 922
>gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo
sapiens]
Length = 1005
Score = 33.5 bits (75), Expect = 0.24
Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 16/70 (22%)
Query: 13 PDYEHVED---ETFPPFPPPASPERQDGEGTEPDEESGNGAP------VPVPP-KRTVKR 62
P+ HV D E +PP+PPP P GE P E+S + P V +PP KRT
Sbjct: 730 PEAPHVLDVYLEEYPPYPPPPYPS---GEPEGPGEDSVSMRPPEITGQVSLPPGKRT--- 783
Query: 63 NIPKLDAQRL 72
N+ K ++R+
Sbjct: 784 NLRKTGSERI 793
>gi|58530845 zyxin [Homo sapiens]
Length = 572
Score = 33.5 bits (75), Expect = 0.24
Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 12/57 (21%)
Query: 18 VEDETFPPFPPPASPERQDGEGTEPDEESGNGAPVPVPPKRTVKRNIPKLDAQRLIS 74
+E+E FP PPP P+EE G AP+P PP+ K + L+ L S
Sbjct: 109 LEEEIFPSPPPP------------PEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSS 153
Score = 28.5 bits (62), Expect = 7.6
Identities = 18/67 (26%), Positives = 24/67 (35%), Gaps = 7/67 (10%)
Query: 11 DLPDYEHVEDETFPPFPPP-------ASPERQDGEGTEPDEESGNGAPVPVPPKRTVKRN 63
D D E FPP PPP A E + P E G P+PP +
Sbjct: 81 DGDDAEGALGGAFPPPPPPIEESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPPQPREK 140
Query: 64 IPKLDAQ 70
+ +D +
Sbjct: 141 VSSIDLE 147
>gi|4508047 zyxin [Homo sapiens]
Length = 572
Score = 33.5 bits (75), Expect = 0.24
Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 12/57 (21%)
Query: 18 VEDETFPPFPPPASPERQDGEGTEPDEESGNGAPVPVPPKRTVKRNIPKLDAQRLIS 74
+E+E FP PPP P+EE G AP+P PP+ K + L+ L S
Sbjct: 109 LEEEIFPSPPPP------------PEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSS 153
Score = 28.5 bits (62), Expect = 7.6
Identities = 18/67 (26%), Positives = 24/67 (35%), Gaps = 7/67 (10%)
Query: 11 DLPDYEHVEDETFPPFPPP-------ASPERQDGEGTEPDEESGNGAPVPVPPKRTVKRN 63
D D E FPP PPP A E + P E G P+PP +
Sbjct: 81 DGDDAEGALGGAFPPPPPPIEESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPPQPREK 140
Query: 64 IPKLDAQ 70
+ +D +
Sbjct: 141 VSSIDLE 147
>gi|126723390 ankyrin repeat domain 24 [Homo sapiens]
Length = 1146
Score = 33.5 bits (75), Expect = 0.24
Identities = 51/223 (22%), Positives = 88/223 (39%), Gaps = 48/223 (21%)
Query: 25 PFPPPASPERQDGEGTEPDEESGNG--------------APVPVPPKRTVKRNIPKLDAQ 70
P PP A E GE + + S +G A +P+P R I +L +
Sbjct: 273 PSPPSALTEDDSGEASSQNSMSSHGKQGAPKKRKAPPPPASIPMPDDRDAYEEIVRLRQE 332
Query: 71 R---LISERGLPALRHVFDKAKFKGKGHEAEDLKMLIRHMEHWAHRLFPKLQFEDFIDRV 127
R L RGL K + + + EA L +L R ++ L + + ++ + R
Sbjct: 333 RGRLLQKIRGLEQ-----HKERRQQESPEASSLHILERQVQELQQLLVERQEEKESLGR- 386
Query: 128 EYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTS-TELDPFLTNLSESEM 186
EV++ R+ L + EN +DVT+ + + L +L +E+
Sbjct: 387 -------EVESLQSRLSL------------LENERENTSYDVTTLQDEEGELPDLPGAEV 427
Query: 187 FASELSRSLTEEQQQRIE--RNKQLALERRQAKLLSNSQTLGN 227
LSR L+ Q+ + + + L R+ +L+ Q L N
Sbjct: 428 L---LSRQLSPSAQEHLASLQEQVAVLTRQNQELMEKVQILEN 467
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 33.1 bits (74), Expect = 0.31
Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 4/71 (5%)
Query: 13 PDYEHVEDETFPPFPPPASPERQDGEGTEP----DEESGNGAPVPVPPKRTVKRNIPKLD 68
P E PP PPPA P D P + E+ A PV PK + + +PKL
Sbjct: 1181 PASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQ 1240
Query: 69 AQRLISERGLP 79
+ + +P
Sbjct: 1241 GSPTPTSKKVP 1251
>gi|116875767 tight junction protein 1 isoform a [Homo sapiens]
Length = 1748
Score = 33.1 bits (74), Expect = 0.31
Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 3/42 (7%)
Query: 17 HVEDETFPPFPPPASPE---RQDGEGTEPDEESGNGAPVPVP 55
H E++T+PP+ P A P+ R D G +P + A PVP
Sbjct: 889 HHENQTYPPYSPQAQPQPIHRIDSPGFKPASQQKAEASSPVP 930
>gi|4557365 Bloom syndrome protein [Homo sapiens]
Length = 1417
Score = 32.3 bits (72), Expect = 0.53
Identities = 35/171 (20%), Positives = 74/171 (43%), Gaps = 24/171 (14%)
Query: 133 KKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTSTELDPFLTNLSESEMFASELS 192
KK T LK++ +F S+ D ++ N+ D ++D F T+ + S
Sbjct: 129 KKSRDTALKKL---------EFSSSPDSLSTINDWD----DMDDFDTSETSKSFVTPPQS 175
Query: 193 RSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLMNTPRAHTVEEVNTDEDQKEES 252
+ Q+ ++ K+ + + L + T+ D+ P + E+++ E+QK++S
Sbjct: 176 HFVRVSTAQKSKKGKRNFFKAQ----LYTTNTVKTDL---PPPSSESEQIDLTEEQKDDS 228
Query: 253 NGLNEDIL---DNPCNDAIANTLNEEETLLDQSFKNVQQQLDATSRNITEA 300
L+ D++ D P + N +E L ++ ++ +N+ EA
Sbjct: 229 EWLSSDVICIDDGPIAEVHINEDAQESDSLKTHLED-ERDNSEKKKNLEEA 278
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 32.3 bits (72), Expect = 0.53
Identities = 46/188 (24%), Positives = 79/188 (42%), Gaps = 16/188 (8%)
Query: 112 HRLFPKLQFEDFIDRVEYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTS 171
HRL +L+ + +V+Y G+ EV +I+ + I+ E+F + ++ E N+
Sbjct: 523 HRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIV-EEFKRDEGKLIEENKR---- 577
Query: 172 TELDPFLTNLSESEMFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLM 231
LS EM + R +TE + Q E + +LAL K + +L N+ +
Sbjct: 578 -----LQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNE--V 630
Query: 232 NTPRAHTVEEVNTDEDQKEESNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLD 291
N VE E E L + L+N +A + EE +Q ++Q+
Sbjct: 631 NEKAKKLVEMEREHEKSLSEIRQLKRE-LEN-VKAKLAQHVKPEEH--EQVKSRLEQKSG 686
Query: 292 ATSRNITE 299
+ ITE
Sbjct: 687 ELGKKITE 694
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 32.3 bits (72), Expect = 0.53
Identities = 46/188 (24%), Positives = 79/188 (42%), Gaps = 16/188 (8%)
Query: 112 HRLFPKLQFEDFIDRVEYLGSKKEVQTCLKRIRLDLPILHEDFVSNNDEVAENNEHDVTS 171
HRL +L+ + +V+Y G+ EV +I+ + I+ E+F + ++ E N+
Sbjct: 536 HRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIV-EEFKRDEGKLIEENKR---- 590
Query: 172 TELDPFLTNLSESEMFASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQTLGNDMLM 231
LS EM + R +TE + Q E + +LAL K + +L N+ +
Sbjct: 591 -----LQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNE--V 643
Query: 232 NTPRAHTVEEVNTDEDQKEESNGLNEDILDNPCNDAIANTLNEEETLLDQSFKNVQQQLD 291
N VE E E L + L+N +A + EE +Q ++Q+
Sbjct: 644 NEKAKKLVEMEREHEKSLSEIRQLKRE-LEN-VKAKLAQHVKPEEH--EQVKSRLEQKSG 699
Query: 292 ATSRNITE 299
+ ITE
Sbjct: 700 ELGKKITE 707
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 32.3 bits (72), Expect = 0.53
Identities = 22/74 (29%), Positives = 38/74 (51%), Gaps = 3/74 (4%)
Query: 188 ASELSRSLTEEQQQRIERNKQLALERRQAKLLSNSQT-LGNDMLMNTPRAHTVEEVNTDE 246
A EL L E ++ R+E ++L RRQ K+L + T LG ++ R E ++
Sbjct: 1261 AGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGE--RAEK 1318
Query: 247 DQKEESNGLNEDIL 260
+ + E+ GL + +L
Sbjct: 1319 ESRRETLGLRQRLL 1332
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 32.0 bits (71), Expect = 0.69
Identities = 37/191 (19%), Positives = 81/191 (42%), Gaps = 28/191 (14%)
Query: 96 EAEDLKMLIRHMEHWAHRLFPKLQFEDFIDRVEYLGSKKEVQTCLKRIRLDLPILHEDFV 155
E E + +L + E + F +LQ + + E L ++++ LK + L + ED +
Sbjct: 1010 EKEKISVLQNNYEK-SQETFKQLQSDFYGRESELLATRQD----LKSVEEKLSLAQEDLI 1064
Query: 156 SNNDEVAENNEHDVTSTELDPFLTNLSESEMFASELSRSLTEEQQQRIERNKQLALERRQ 215
SN +++ N+ + E + + L + +++QQ ER K L +++
Sbjct: 1065 SNRNQIGNQNK-------------LIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKE 1111
Query: 216 AKLLSNSQTLGNDMLMNTPRAHTVEEVNTDEDQKEESNGLNEDILDNPCND--AIANTLN 273
L +++ + +EE+ Q++E LNE++ + I N +
Sbjct: 1112 KSLKE------KELVNEKSKLAEIEEIKC--RQEKEITKLNEELKSHKLESIKEITNLKD 1163
Query: 274 EEETLLDQSFK 284
++ L+ Q +
Sbjct: 1164 AKQLLIQQKLE 1174
>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
sapiens]
Length = 955
Score = 32.0 bits (71), Expect = 0.69
Identities = 42/213 (19%), Positives = 89/213 (41%), Gaps = 29/213 (13%)
Query: 93 KGHEAEDLKMLIRHMEHWAHRLFPKLQFEDFIDRVEYLGSKKEVQTCLKRIRLDLPILHE 152
K +E E+LK L R +H KL+ K+VQT ++ ++ + E
Sbjct: 290 KNNEIEELKTLYRSKQHETEETIRKLE--------------KKVQTLIRDCQV-IRETKE 334
Query: 153 DFVSNNDEVAENNEHDVTSTELDPFLTNLSESEMFASELSRSLTEEQQQRIERNKQLALE 212
D ++ ++ E + + + ++E E +L + TE Q+ +E + + L
Sbjct: 335 DQIAELKKICEQSTESLNNDWEKKLHNAVAEMEQEKFDLQKQHTENIQELLE-DTNVRLN 393
Query: 213 RRQAKLLSNSQTLGNDMLMNTPRAHTV----EEVNTDEDQKEESNGLNEDILDNPCND-- 266
+ +++ ++ +Q+ + + R + E N + + E C++
Sbjct: 394 KMESEYMAQTQSTNHMIKELEARVQQLTGEAENSNLQRQKLIQEKAELERCYQITCSELQ 453
Query: 267 ---AIANTLNEEETLL----DQSFKNVQQQLDA 292
A NTL++E+ L +Q+ K +Q + DA
Sbjct: 454 EVKARRNTLHKEKDHLVNDYEQNMKLLQTKYDA 486
>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
Length = 547
Score = 32.0 bits (71), Expect = 0.69
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 22 TFPPFPPPASPERQDGEGTEPDEESGNGAPVPVPPKRTVKRNIPKLDAQRLISERGL 78
T PP PPP P + P P P+P K+ + RNI ++ Q+ ++R L
Sbjct: 420 TPPPPPPPPPPPPPSSQRLPPPPPP---PPPPLPEKKLITRNIAEVIKQQESAQRAL 473
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.131 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,617,067
Number of Sequences: 37866
Number of extensions: 690602
Number of successful extensions: 4078
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 181
Number of HSP's that attempted gapping in prelim test: 3911
Number of HSP's gapped (non-prelim): 362
length of query: 301
length of database: 18,247,518
effective HSP length: 102
effective length of query: 199
effective length of database: 14,385,186
effective search space: 2862652014
effective search space used: 2862652014
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.