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Search of human proteins with 156938343
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156938343 talin 2 [Homo sapiens]
(2542 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156938343 talin 2 [Homo sapiens] 4851 0.0
gi|223029410 talin 1 [Homo sapiens] 3768 0.0
gi|38045919 huntingtin interacting protein 1 [Homo sapiens] 130 2e-29
gi|48762942 huntingtin interacting protein-1-related [Homo sapiens] 108 9e-23
gi|239750456 PREDICTED: similar to KIAA0655 protein [Homo sapiens] 108 9e-23
gi|13446229 mesoderm development candidate 1 [Homo sapiens] 100 1e-20
gi|4506467 radixin [Homo sapiens] 67 3e-10
gi|40254949 erythrocyte membrane protein band 4.1 like 5 [Homo s... 66 5e-10
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 64 1e-09
gi|110624794 erythrocyte membrane protein band 4.1 like 4B isofo... 64 1e-09
gi|110624790 erythrocyte membrane protein band 4.1 like 4B isofo... 64 1e-09
gi|4505257 moesin [Homo sapiens] 63 4e-09
gi|29789006 fermitin family homolog 2 isoform 1 [Homo sapiens] 63 4e-09
gi|87042275 erythrocyte protein band 4.1-like 4 [Homo sapiens] 62 6e-09
gi|30061491 erythrocyte membrane protein band 4.1-like 1 isoform... 62 7e-09
gi|30061489 erythrocyte membrane protein band 4.1-like 1 isoform... 62 7e-09
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 62 9e-09
gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Ho... 62 9e-09
gi|201861813 fermitin family homolog 2 isoform 2 [Homo sapiens] 62 9e-09
gi|161702986 ezrin [Homo sapiens] 61 1e-08
gi|21614499 ezrin [Homo sapiens] 61 1e-08
gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens] 61 2e-08
gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens] 61 2e-08
gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens] 61 2e-08
gi|4557795 neurofibromin 2 isoform 1 [Homo sapiens] 61 2e-08
gi|116686114 kindlin-1 [Homo sapiens] 60 2e-08
gi|42716289 erythrocyte membrane protein band 4.1 (elliptocytosi... 60 3e-08
gi|28626504 fermitin family homolog 3 short form [Homo sapiens] 59 6e-08
gi|41281905 fermitin family homolog 3 long form [Homo sapiens] 59 6e-08
gi|223941879 protein tyrosine phosphatase, non-receptor type 3 i... 58 1e-07
>gi|156938343 talin 2 [Homo sapiens]
Length = 2542
Score = 4851 bits (12584), Expect = 0.0
Identities = 2542/2542 (100%), Positives = 2542/2542 (100%)
Query: 1 MVALSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRK 60
MVALSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRK
Sbjct: 1 MVALSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRK 60
Query: 61 GIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSR 120
GIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSR
Sbjct: 61 GIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSR 120
Query: 121 IGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSR 180
IGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSR
Sbjct: 121 IGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSR 180
Query: 181 TFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEF 240
TFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEF
Sbjct: 181 TFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEF 240
Query: 241 GGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVK 300
GGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVK
Sbjct: 241 GGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVK 300
Query: 301 YVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVK 360
YVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVK
Sbjct: 301 YVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVK 360
Query: 361 RWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEES 420
RWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEES
Sbjct: 361 RWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEES 420
Query: 421 TMLEESVSPKKSTILQQQFNRTGKAEHGSVALPAVMRSGSSGPETFNVGSMPSPQQQVMV 480
TMLEESVSPKKSTILQQQFNRTGKAEHGSVALPAVMRSGSSGPETFNVGSMPSPQQQVMV
Sbjct: 421 TMLEESVSPKKSTILQQQFNRTGKAEHGSVALPAVMRSGSSGPETFNVGSMPSPQQQVMV 480
Query: 481 GQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVD 540
GQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVD
Sbjct: 481 GQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVD 540
Query: 541 ESKHEIHSQVDAITAGTASVVNLTAGDPADTDYTAVGCAITTISSNLTEMSKGVKLLAAL 600
ESKHEIHSQVDAITAGTASVVNLTAGDPADTDYTAVGCAITTISSNLTEMSKGVKLLAAL
Sbjct: 541 ESKHEIHSQVDAITAGTASVVNLTAGDPADTDYTAVGCAITTISSNLTEMSKGVKLLAAL 600
Query: 601 MDDEVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEPRQTVLTAAGSIGQASGDLLRQIGE 660
MDDEVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEPRQTVLTAAGSIGQASGDLLRQIGE
Sbjct: 601 MDDEVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEPRQTVLTAAGSIGQASGDLLRQIGE 660
Query: 661 NETDERFQDVLMSLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLV 720
NETDERFQDVLMSLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLV
Sbjct: 661 NETDERFQDVLMSLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLV 720
Query: 721 ACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAATTDSELLKQVSAAASVVSQA 780
ACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAATTDSELLKQVSAAASVVSQA
Sbjct: 721 ACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAATTDSELLKQVSAAASVVSQA 780
Query: 781 LHDLLQHVRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLV 840
LHDLLQHVRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLV
Sbjct: 781 LHDLLQHVRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLV 840
Query: 841 NAMRSDAEAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGL 900
NAMRSDAEAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGL
Sbjct: 841 NAMRSDAEAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGL 900
Query: 901 RVATNAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAVSNKNPAAQQQLVQSCKA 960
RVATNAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAVSNKNPAAQQQLVQSCKA
Sbjct: 901 RVATNAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAVSNKNPAAQQQLVQSCKA 960
Query: 961 VADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAM 1020
VADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAM
Sbjct: 961 VADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAM 1020
Query: 1021 QLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNTVQTLKNELQDAKMAAVESQLKP 1080
QLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNTVQTLKNELQDAKMAAVESQLKP
Sbjct: 1021 QLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNTVQTLKNELQDAKMAAVESQLKP 1080
Query: 1081 LPGETLEKCAQDLGSTSKAVGSSMAQLLTCAAQGNEHYTGVAARETAQALKTLAQAARGV 1140
LPGETLEKCAQDLGSTSKAVGSSMAQLLTCAAQGNEHYTGVAARETAQALKTLAQAARGV
Sbjct: 1081 LPGETLEKCAQDLGSTSKAVGSSMAQLLTCAAQGNEHYTGVAARETAQALKTLAQAARGV 1140
Query: 1141 AASTTDPAAAHAMLDSARDVMEGSAMLIQEAKQALIAPGDAERQQRLAQVAKAVSHSLNN 1200
AASTTDPAAAHAMLDSARDVMEGSAMLIQEAKQALIAPGDAERQQRLAQVAKAVSHSLNN
Sbjct: 1141 AASTTDPAAAHAMLDSARDVMEGSAMLIQEAKQALIAPGDAERQQRLAQVAKAVSHSLNN 1200
Query: 1201 CVNCLPGQKDVDVALKSIGESSKKLLVDSLPPSTKPFQEAQSELNQAAADLNQSAGEVVH 1260
CVNCLPGQKDVDVALKSIGESSKKLLVDSLPPSTKPFQEAQSELNQAAADLNQSAGEVVH
Sbjct: 1201 CVNCLPGQKDVDVALKSIGESSKKLLVDSLPPSTKPFQEAQSELNQAAADLNQSAGEVVH 1260
Query: 1261 ATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQIQVIGNLKNISMASSKLLLA 1320
ATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQIQVIGNLKNISMASSKLLLA
Sbjct: 1261 ATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQIQVIGNLKNISMASSKLLLA 1320
Query: 1321 AKSLSVDPGAPNAKNLLAAAARAVTESINQLITLCTQQAPGQKECDNALRELETVKGMLD 1380
AKSLSVDPGAPNAKNLLAAAARAVTESINQLITLCTQQAPGQKECDNALRELETVKGMLD
Sbjct: 1321 AKSLSVDPGAPNAKNLLAAAARAVTESINQLITLCTQQAPGQKECDNALRELETVKGMLD 1380
Query: 1381 NPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTE 1440
NPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTE
Sbjct: 1381 NPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTE 1440
Query: 1441 AAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQVLSAATIV 1500
AAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQVLSAATIV
Sbjct: 1441 AAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQVLSAATIV 1500
Query: 1501 AKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKC 1560
AKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKC
Sbjct: 1501 AKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKC 1560
Query: 1561 RIATAPLIEAVENLTAFASNPEFVSIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTAR 1620
RIATAPLIEAVENLTAFASNPEFVSIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTAR
Sbjct: 1561 RIATAPLIEAVENLTAFASNPEFVSIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTAR 1620
Query: 1621 SLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQA 1680
SLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQA
Sbjct: 1621 SLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQA 1680
Query: 1681 SLAAVSQSLATRDDISVEALQEQLTSVVQEIGHLIDPIATAARGEAAQLGHKVTQLASYF 1740
SLAAVSQSLATRDDISVEALQEQLTSVVQEIGHLIDPIATAARGEAAQLGHKVTQLASYF
Sbjct: 1681 SLAAVSQSLATRDDISVEALQEQLTSVVQEIGHLIDPIATAARGEAAQLGHKVTQLASYF 1740
Query: 1741 EPLILAAVGVASKILDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEA 1800
EPLILAAVGVASKILDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEA
Sbjct: 1741 EPLILAAVGVASKILDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEA 1800
Query: 1801 AQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEPKGTFVDYQTTVVK 1860
AQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEPKGTFVDYQTTVVK
Sbjct: 1801 AQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEPKGTFVDYQTTVVK 1860
Query: 1861 YSKAIAVTAQEMMTKSVTNPEELGGLASQMTSDYGHLAFQGQMAAATAEPEEIGFQIRTR 1920
YSKAIAVTAQEMMTKSVTNPEELGGLASQMTSDYGHLAFQGQMAAATAEPEEIGFQIRTR
Sbjct: 1861 YSKAIAVTAQEMMTKSVTNPEELGGLASQMTSDYGHLAFQGQMAAATAEPEEIGFQIRTR 1920
Query: 1921 VQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACI 1980
VQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACI
Sbjct: 1921 VQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACI 1980
Query: 1981 TAATAVSGIIADLDTTIMFATAGTLNAENSETFADHRENILKTAKALVEDTKLLVSGAAS 2040
TAATAVSGIIADLDTTIMFATAGTLNAENSETFADHRENILKTAKALVEDTKLLVSGAAS
Sbjct: 1981 TAATAVSGIIADLDTTIMFATAGTLNAENSETFADHRENILKTAKALVEDTKLLVSGAAS 2040
Query: 2041 TPDKLAQAAQSSAATITQLAEVVKLGAASLGSDDPETQVVLINAIKDVAKALSDLISATK 2100
TPDKLAQAAQSSAATITQLAEVVKLGAASLGSDDPETQVVLINAIKDVAKALSDLISATK
Sbjct: 2041 TPDKLAQAAQSSAATITQLAEVVKLGAASLGSDDPETQVVLINAIKDVAKALSDLISATK 2100
Query: 2101 GAASKPVDDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIECIKQELTV 2160
GAASKPVDDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIECIKQELTV
Sbjct: 2101 GAASKPVDDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIECIKQELTV 2160
Query: 2161 FQSKDVPEKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDMLTAC 2220
FQSKDVPEKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDMLTAC
Sbjct: 2161 FQSKDVPEKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDMLTAC 2220
Query: 2221 KQASFHPDVSDEVRTRALRFGTECTLGYLDLLEHVLVILQKPTPEFKQQLAAFSKRVAGA 2280
KQASFHPDVSDEVRTRALRFGTECTLGYLDLLEHVLVILQKPTPEFKQQLAAFSKRVAGA
Sbjct: 2221 KQASFHPDVSDEVRTRALRFGTECTLGYLDLLEHVLVILQKPTPEFKQQLAAFSKRVAGA 2280
Query: 2281 VTELIQAAEAMKGTEWVDPEDPTVIAETELLGAAASIEAAAKKLEQLKPRAKPKQADETL 2340
VTELIQAAEAMKGTEWVDPEDPTVIAETELLGAAASIEAAAKKLEQLKPRAKPKQADETL
Sbjct: 2281 VTELIQAAEAMKGTEWVDPEDPTVIAETELLGAAASIEAAAKKLEQLKPRAKPKQADETL 2340
Query: 2341 DFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGSIPANAADDGQWSQGLISAARM 2400
DFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGSIPANAADDGQWSQGLISAARM
Sbjct: 2341 DFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGSIPANAADDGQWSQGLISAARM 2400
Query: 2401 VAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAA 2460
VAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAA
Sbjct: 2401 VAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAA 2460
Query: 2461 GNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKFVGGIAQIIAAQEEMLKKERELEEARK 2520
GNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKFVGGIAQIIAAQEEMLKKERELEEARK
Sbjct: 2461 GNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKFVGGIAQIIAAQEEMLKKERELEEARK 2520
Query: 2521 KLAQIRQQQYKFLPTELREDEG 2542
KLAQIRQQQYKFLPTELREDEG
Sbjct: 2521 KLAQIRQQQYKFLPTELREDEG 2542
>gi|223029410 talin 1 [Homo sapiens]
Length = 2541
Score = 3768 bits (9772), Expect = 0.0
Identities = 1936/2543 (76%), Positives = 2250/2543 (88%), Gaps = 6/2543 (0%)
Query: 1 MVALSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRK 60
MVALSLKI + NVVKTMQFEPST VYDACR+IRER+PEA G SD+GLFLSD+DP+K
Sbjct: 1 MVALSLKISIG--NVVKTMQFEPSTMVYDACRIIRERIPEAPAGPPSDFGLFLSDDDPKK 58
Query: 61 GIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSR 120
GIWLEAG+ LDYYMLRNGD +EY+KKQRP KIRMLDG+VKT+MVDDSKTV ++L+TIC+R
Sbjct: 59 GIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICAR 118
Query: 121 IGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSR 180
IGITN++EYSL++E +EEKKEE TGTL+KD+TLLRDE+KMEKLK KLHTDD+LNWLDH R
Sbjct: 119 IGITNHDEYSLVRELMEEKKEEITGTLRKDKTLLRDEKKMEKLKQKLHTDDELNWLDHGR 178
Query: 181 TFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEF 240
T REQGV+E+ETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSF+KACEF
Sbjct: 179 TLREQGVEEHETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEF 238
Query: 241 GGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVK 300
GFQ QIQFGPH E KHK GFLDLK+FLPKEY+KQ+G E++IFQ HKNCG+MSEIEAKV+
Sbjct: 239 AGFQCQIQFGPHNEQKHKAGFLDLKDFLPKEYVKQKG-ERKIFQAHKNCGQMSEIEAKVR 297
Query: 301 YVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVK 360
YVKLARSL+TYGVSFFLVKEKMKGKNKLVPRLLGITK+ VMRVDEKTKEV+QEW LT +K
Sbjct: 298 YVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWNLTNIK 357
Query: 361 RWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEES 420
RWAASPKSFTLDFG+YQ+ YYSVQTTEGEQI+QLIAGYIDIILKKK+SKD FGLEGDEES
Sbjct: 358 RWAASPKSFTLDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEES 417
Query: 421 TMLEESVSPKKSTILQQQFNRTGKAEHGSVALPAVMRSGSSGPETFNVGSMPSPQQQVMV 480
TMLE+SVSPKKST+LQQQ+NR GK EHGSVALPA+MRSG+SGPE F VGSMP QQQ+
Sbjct: 418 TMLEDSVSPKKSTVLQQQYNRVGKVEHGSVALPAIMRSGASGPENFQVGSMPPAQQQITS 477
Query: 481 GQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVD 540
GQMHRGHMPPLTSAQQAL GTIN+SM AVQ AQ L + D+LPPLGQD AS+ W +NK+D
Sbjct: 478 GQMHRGHMPPLTSAQQALTGTINSSMQAVQAAQATLDDFDTLPPLGQDAASKAWRKNKMD 537
Query: 541 ESKHEIHSQVDAITAGTASVVNLTAGDPADTDYTAVGCAITTISSNLTEMSKGVKLLAAL 600
ESKHEIHSQVDAITAGTASVVNLTAGDPA+TDYTAVGCA+TTISSNLTEMS+GVKLLAAL
Sbjct: 538 ESKHEIHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAAL 597
Query: 601 MDDEVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEPRQTVLTAAGSIGQASGDLLRQIGE 660
++DE GSG LL+AA+ LAGAVS+LL++ QP S EPRQ +L AAG++GQASG+LL+QIGE
Sbjct: 598 LEDEGGSGRPLLQAAKGLAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQIGE 657
Query: 661 NETDERFQDVLMSLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLV 720
++TD FQD LM LAKAVA+AAA LVLKAK+VAQ ED+ LQ +VIAAATQCALSTSQLV
Sbjct: 658 SDTDPHFQDALMQLAKAVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLV 717
Query: 721 ACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAATTDSELLKQVSAAASVVSQA 780
AC KVV+PTISSPVCQEQL+EAG+LV ++VE CV A QAAT D +LL+ V AAA+ V+QA
Sbjct: 718 ACTKVVAPTISSPVCQEQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQA 777
Query: 781 LHDLLQHVRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLV 840
L++LLQHV+ A+ P GRYDQATDTI+ VTE+IFSSMGDAGEMVRQAR+LAQATSDLV
Sbjct: 778 LNELLQHVKAHATGAGPAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLV 837
Query: 841 NAMRSDAEAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGL 900
NA+++DAE E D+ENS+KLL+AAK+LAD+TA+MVEAAKGAAA+P++E+QQQRLREAAEGL
Sbjct: 838 NAIKADAEGESDLENSRKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGL 897
Query: 901 RVATNAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAVSNKNPAAQQQL-VQSCK 959
R+ATNAAAQNAIKKK+V RLE AAKQAAA+ATQTIAA+Q+AA + K A Q L VQSCK
Sbjct: 898 RMATNAAAQNAIKKKLVQRLEHAAKQAAASATQTIAAAQHAASTPKASAGPQPLLVQSCK 957
Query: 960 AVADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAA 1019
AVA+ IP LVQGVRGSQAQ + SAQLALI +SQ+FLQPG KMV++AKA+VPT+ DQA+A
Sbjct: 958 AVAEQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTIQDQASA 1017
Query: 1020 MQLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNTVQTLKNELQDAKMAAVESQLK 1079
MQLSQCAKNL T+LAELRTA+QKA EACGP+E+DSAL+ VQ L+ +LQ+ K AA + +LK
Sbjct: 1018 MQLSQCAKNLGTALAELRTAAQKAQEACGPLEMDSALSVVQNLEKDLQEVKAAARDGKLK 1077
Query: 1080 PLPGETLEKCAQDLGSTSKAVGSSMAQLLTCAAQGNEHYTGVAARETAQALKTLAQAARG 1139
PLPGET+EKC QDLG+++KAV S++AQLL AQGNE+Y G+AAR+ A L++LAQAARG
Sbjct: 1078 PLPGETMEKCTQDLGNSTKAVSSAIAQLLGEVAQGNENYAGIAARDVAGGLRSLAQAARG 1137
Query: 1140 VAASTTDPAAAHAMLDSARDVMEGSAMLIQEAKQALIAPGDAERQQRLAQVAKAVSHSLN 1199
VAA T+DPA +LD+A DV++ ++ LI+EAK+A PGD E QQRLAQVAKAV+ +LN
Sbjct: 1138 VAALTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVAKAVTQALN 1197
Query: 1200 NCVNCLPGQKDVDVALKSIGESSKKLLVDSLPPSTKPFQEAQSELNQAAADLNQSAGEVV 1259
CV+CLPGQ+DVD AL+++G++SK+LL DSLPPST FQEAQS LN+AAA LNQ+A E+V
Sbjct: 1198 RCVSCLPGQRDVDNALRAVGDASKRLLSDSLPPSTGTFQEAQSRLNEAAAGLNQAATELV 1257
Query: 1260 HATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQIQVIGNLKNISMASSKLLL 1319
A+RG +LA ASG+F DF FL+AG+EMAGQA ++ED+ QV+ NLK ISM+SSKLLL
Sbjct: 1258 QASRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISMSSSKLLL 1317
Query: 1320 AAKSLSVDPGAPNAKNLLAAAARAVTESINQLITLCTQQAPGQKECDNALRELETVKGML 1379
AAK+LS DP APN K+ LAAAARAVT+SINQLIT+CTQQAPGQKECDNALRELETV+ +L
Sbjct: 1318 AAKALSTDPAAPNLKSQLAAAARAVTDSINQLITMCTQQAPGQKECDNALRELETVRELL 1377
Query: 1380 DNPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLT 1439
+NP +P++D+SYF C++SVMENSKVLGE+M GISQNAK G+LP FG+ + ASKALCG T
Sbjct: 1378 ENPVQPINDMSYFGCLDSVMENSKVLGEAMTGISQNAKNGNLPEFGDAISTASKALCGFT 1437
Query: 1440 EAAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQVLSAATI 1499
EAAAQAAYLVG+SDPNSQAG QGLV+P QFARANQAIQMACQ+L +PG + +QVLSAATI
Sbjct: 1438 EAAAQAAYLVGVSDPNSQAGQQGLVEPTQFARANQAIQMACQSLGEPGCTQAQVLSAATI 1497
Query: 1500 VAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNK 1559
VAKHTSALCN+CR+AS++T NP AKR FVQSAKEVANSTANLVKTIKALDG F+E+NR +
Sbjct: 1498 VAKHTSALCNSCRLASARTTNPTAKRQFVQSAKEVANSTANLVKTIKALDGAFTEENRAQ 1557
Query: 1560 CRIATAPLIEAVENLTAFASNPEFVSIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTA 1619
CR ATAPL+EAV+NL+AFASNPEF SIPAQIS EG A EPI++SAKTMLES+ LI+TA
Sbjct: 1558 CRAATAPLLEAVDNLSAFASNPEFSSIPAQISPEGRAAMEPIVISAKTMLESAGGLIQTA 1617
Query: 1620 RSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQ 1679
R+LA+NP+DPP+WSVLAGHS TVSDSIK LITS+RDKAPGQ EC+ +I +N C+RD++Q
Sbjct: 1618 RALAVNPRDPPSWSVLAGHSRTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQ 1677
Query: 1680 ASLAAVSQSLATRDDISVEALQEQLTSVVQEIGHLIDPIATAARGEAAQLGHKVTQLASY 1739
ASLAAVSQ LA R+ IS EAL Q+ + VQEI HLI+P+A AAR EA+QLGHKV+Q+A Y
Sbjct: 1678 ASLAAVSQQLAPREGISQEALHTQMLTAVQEISHLIEPLANAARAEASQLGHKVSQMAQY 1737
Query: 1740 FEPLILAAVGVASKILDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPK-AQHTHDAIT 1798
FEPL LAAVG ASK L H QQM +LDQTKTLAESALQ+LY AKE GGNPK A HT +A+
Sbjct: 1738 FEPLTLAAVGAASKTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALE 1797
Query: 1799 EAAQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEPKGTFVDYQTTV 1858
EA Q+M EAV+D+ TLNEAAS G+VGGMVD+I +A+++LDEG EP+G+FVDYQTT+
Sbjct: 1798 EAVQMMTEAVEDLTTTLNEAASAAGVVGGMVDSITQAINQLDEGPMGEPEGSFVDYQTTM 1857
Query: 1859 VKYSKAIAVTAQEMMTKSVTNPEELGGLASQMTSDYGHLAFQGQMAAATAEPEEIGFQIR 1918
V+ +KAIAVT QEM+TKS T+PEELG LA+Q+TSDYG LA + + AA AE EEIG I+
Sbjct: 1858 VRTAKAIAVTVQEMVTKSNTSPEELGPLANQLTSDYGRLASEAKPAAVAAENEEIGSHIK 1917
Query: 1919 TRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQA 1978
RVQ+LGHGC LV KAGALQ P+D+YTK+ELIECAR V+EKVS VL+ALQAGN+GTQA
Sbjct: 1918 HRVQELGHGCAALVTKAGALQCSPSDAYTKKELIECARRVSEKVSHVLAALQAGNRGTQA 1977
Query: 1979 CITAATAVSGIIADLDTTIMFATAGTLNAENSETFADHRENILKTAKALVEDTKLLVSGA 2038
CITAA+AVSGIIADLDTTIMFATAGTLN E +ETFADHRE ILKTAK LVEDTK+LV A
Sbjct: 1978 CITAASAVSGIIADLDTTIMFATAGTLNREGTETFADHREGILKTAKVLVEDTKVLVQNA 2037
Query: 2039 ASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSDDPETQVVLINAIKDVAKALSDLISA 2098
A + +KLAQAAQSS ATIT+LA+VVKLGAASLG++DPETQVVLINA+KDVAKAL DLISA
Sbjct: 2038 AGSQEKLAQAAQSSVATITRLADVVKLGAASLGAEDPETQVVLINAVKDVAKALGDLISA 2097
Query: 2099 TKGAASKPVDDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIECIKQEL 2158
TK AA K DDP+++QLK +AKVMVTNVTSLLKTVKAVEDEAT+GTRALEAT E I+QEL
Sbjct: 2098 TKAAAGKVGDDPAVWQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATTEHIRQEL 2157
Query: 2159 TVFQSKDVPEKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDMLT 2218
VF S + P KTS+PE+ IRMTKGITMATAKAVAAGNSCRQEDVIATANLSR+A++DML
Sbjct: 2158 AVFCSPEPPAKTSTPEDFIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRRAIADMLR 2217
Query: 2219 ACKQASFHPDVSDEVRTRALRFGTECTLGYLDLLEHVLVILQKPTPEFKQQLAAFSKRVA 2278
ACK+A++HP+V+ +VR RAL +G EC GYL+LL+HVL+ LQKP+PE KQQL SKRVA
Sbjct: 2218 ACKEAAYHPEVAPDVRLRALHYGRECANGYLELLDHVLLTLQKPSPELKQQLTGHSKRVA 2277
Query: 2279 GAVTELIQAAEAMKGTEWVDPEDPTVIAETELLGAAASIEAAAKKLEQLKPRAKPKQADE 2338
G+VTELIQAAEAMKGTEWVDPEDPTVIAE ELLGAAA+IEAAAKKLEQLKPRAKPK+ADE
Sbjct: 2278 GSVTELIQAAEAMKGTEWVDPEDPTVIAENELLGAAAAIEAAAKKLEQLKPRAKPKEADE 2337
Query: 2339 TLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGSIPANAADDGQWSQGLISAA 2398
+L+FEEQILEAAKSIAAATSALVK+ASAAQRELVAQGKVG+IPANA DDGQWSQGLISAA
Sbjct: 2338 SLNFEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAIPANALDDGQWSQGLISAA 2397
Query: 2399 RMVAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQ 2458
RMVAAAT++LCEAANA+VQGHAS+EKLISSAKQVAASTAQLLVACKVKADQDSEAM+RLQ
Sbjct: 2398 RMVAAATNNLCEAANAAVQGHASQEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQ 2457
Query: 2459 AAGNAVKRASDNLVRAAQK-AAFGKADDDDVVVKTKFVGGIAQIIAAQEEMLKKERELEE 2517
AAGNAVKRASDNLV+AAQK AAF + +++ VVVK K VGGIAQIIAAQEEML+KERELEE
Sbjct: 2458 AAGNAVKRASDNLVKAAQKAAAFEEQENETVVVKEKMVGGIAQIIAAQEEMLRKERELEE 2517
Query: 2518 ARKKLAQIRQQQYKFLPTELRED 2540
ARKKLAQIRQQQYKFLP+ELR++
Sbjct: 2518 ARKKLAQIRQQQYKFLPSELRDE 2540
>gi|38045919 huntingtin interacting protein 1 [Homo sapiens]
Length = 1037
Score = 130 bits (327), Expect = 2e-29
Identities = 124/534 (23%), Positives = 239/534 (44%), Gaps = 71/534 (13%)
Query: 2011 ETFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASL 2070
ET A N L ++ LVSGAA ++L+ + T +LA + L
Sbjct: 557 ETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQDTQLKLASTEE-SMCQL 615
Query: 2071 GSDDPETQVVLINAIKDVAKALSDLISATKGAASKPVDDPSMYQLKGAAKVMVTNVTSLL 2130
D + +++L+ + K + + D ++ +++P + G+A +++ VTS+
Sbjct: 616 AKD--QRKMLLVGSRKAAEQVIQDALNQ--------LEEPPLISCAGSADHLLSTVTSIS 665
Query: 2131 KTVKAVEDEATRGTRALEATIECIKQELTVFQSKDVPEKTSSPEESIRMTKGITMATAKA 2190
++ +E K + + PE+ + IT+
Sbjct: 666 SCIEQLE--------------------------KSWSQYLACPEDISGLLHSITLL---- 695
Query: 2191 VAAGNSCRQEDVIATANLSRKAVSDMLTACKQASFHPDVSDEVRTRALRFGTECTLGYLD 2250
A+L+ A++ T C +A P+ +D + ++G E TL YL
Sbjct: 696 ---------------AHLTSDAIAHGATTCLRAP--PEPADSLTEACKQYGRE-TLAYLA 737
Query: 2251 LLEHVLVILQKPTPEFKQQLAAFSKRVAGAVTELIQAAEAMKGTEWVDPEDPTVIAETEL 2310
LE + + + L+ ++ EL+ +K E D + + E+
Sbjct: 738 SLEEEGSLENADSTAMRNCLS----KIKAIGEELLPRGLDIKQEELGD------LVDKEM 787
Query: 2311 LGAAASIEAAAKKLEQLKPRAKPKQADETLDFEEQILEAAKSIAAATSALVKSASAAQRE 2370
+A+IE A ++E++ +++ L+ E+IL S+ A L+ ++ QRE
Sbjct: 788 AATSAAIETATARIEEMLSKSRAGDTGVKLEVNERILGCCTSLMQAIQVLIVASKDLQRE 847
Query: 2371 LVAQGKVGSIPANA-ADDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLISSA 2429
+V G+ + P A + +W++GLISA++ V + + +AA+ VQG E+L+ +
Sbjct: 848 IVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGKFEELMVCS 907
Query: 2430 KQVAASTAQLLVACKVKADQDSEAMRRLQAAGNAVKRASDNLVRAAQKAAFGKADDDDVV 2489
++AASTAQL+ A KVKAD+DS + +LQ A V +A+ +V + + D++
Sbjct: 908 HEIAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQIEETDNMD 967
Query: 2490 VKTKFVGGI-AQIIAAQEEMLKKERELEEARKKLAQIRQQQYKFLPTELREDEG 2542
+ + I Q + +Q +L+ E EL++ R+KL ++R++ Y+ +EG
Sbjct: 968 FSSMTLTQIKRQEMDSQVRVLELENELQKERQKLGELRKKHYELAGVAEGWEEG 1021
Score = 38.9 bits (89), Expect = 0.065
Identities = 51/194 (26%), Positives = 78/194 (40%), Gaps = 48/194 (24%)
Query: 566 GDPADTDYTAVGCAITTISSNLTEMSKGVKLLAALMDDEVGSGEDLLRAARTLAGAVSDL 625
GD D + A AI T ++ + EM L G L + G + L
Sbjct: 780 GDLVDKEMAATSAAIETATARIEEM---------LSKSRAGDTGVKLEVNERILGCCTSL 830
Query: 626 LKAVQPTSGEPRQTVLTAAGSIGQASGDLLRQIGEN-----------ETDERFQDVLMSL 674
++A+Q VL A S DL R+I E+ + R+ + L+S
Sbjct: 831 MQAIQ---------VLIVA------SKDLQREIVESGRGTASPKEFYAKNSRWTEGLISA 875
Query: 675 AKAVANAAAMLVLKAKNVAQVAEDTVLQNR-----VIAAATQCALSTSQLVACAKVVSPT 729
+KAV A ++V A D V+Q R ++ + + A ST+QLVA +KV +
Sbjct: 876 SKAVGWGATVMV--------DAADLVVQGRGKFEELMVCSHEIAASTAQLVAASKVKADK 927
Query: 730 ISSPVCQEQLIEAG 743
S + Q Q G
Sbjct: 928 DSPNLAQLQQASRG 941
>gi|48762942 huntingtin interacting protein-1-related [Homo sapiens]
Length = 1068
Score = 108 bits (269), Expect = 9e-23
Identities = 73/241 (30%), Positives = 130/241 (53%), Gaps = 12/241 (4%)
Query: 2297 VDPEDPTVIAETELLGAAASIEAAAKKLEQLKPRAKPKQADETLDFEEQILEAAKSIAAA 2356
V E+ + + E+ +A+IE A +++E + +A+ + L+ E+IL + + A
Sbjct: 774 VRQEELGAVVDKEMAATSAAIEDAVRRIEDMMNQARHASSGVKLEVNERILNSCTDLMKA 833
Query: 2357 TSALVKSASAAQRELVAQGKVGSIPANA-ADDGQWSQGLISAARMVAAATSSLCEAANAS 2415
LV ++++ Q+E+V G+ + A + +W++GLISA++ V + L EAA+
Sbjct: 834 IRLLVTTSTSLQKEIVESGRGAATQQEFYAKNSRWTEGLISASKAVGWGATQLVEAADKV 893
Query: 2416 VQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAAGNAVKRASDNLVRAA 2475
V E+LI + ++AASTAQL+ A KVKA++ S + RLQ V + N+V A+
Sbjct: 894 VLHTGKYEELIVCSHEIAASTAQLVAASKVKANKHSPHLSRLQECSRTVNERAANVV-AS 952
Query: 2476 QKAAFGKADDDDVVVKTKFVGGIAQIIAAQEEM------LKKERELEEARKKLAQIRQQQ 2529
K+ + +D D T G++ I ++EM L+ E+ LE R +L ++R+Q
Sbjct: 953 TKSGQEQIEDRD----TMDFSGLSLIKLKKQEMETQVRVLELEKTLEAERMRLGELRKQH 1008
Query: 2530 Y 2530
Y
Sbjct: 1009 Y 1009
Score = 35.8 bits (81), Expect = 0.55
Identities = 45/190 (23%), Positives = 80/190 (42%), Gaps = 25/190 (13%)
Query: 590 MSKGVKLLAALMDDEVGSGEDLLRAARTLAGAV------------SDLLKAVQ--PTSGE 635
+ K + +A ++D V ED++ AR + V +DL+KA++ T+
Sbjct: 783 VDKEMAATSAAIEDAVRRIEDMMNQARHASSGVKLEVNERILNSCTDLMKAIRLLVTTST 842
Query: 636 PRQTVLTAAGSIGQASGDLLRQIGENETDERFQDVLMSLAKAVANAAAMLVLKAKNVAQV 695
Q + +G + + + R+ + L+S +KAV A LV A V
Sbjct: 843 SLQKEIVESGRGAATQQEFYAK------NSRWTEGLISASKAVGWGATQLVEAADKVVL- 895
Query: 696 AEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVR 755
T +I + + A ST+QLVA +KV + S + +L E + V+ N V
Sbjct: 896 --HTGKYEELIVCSHEIAASTAQLVAASKVKANKHSPHL--SRLQECSRTVNERAANVVA 951
Query: 756 ACQAATTDSE 765
+ ++ E
Sbjct: 952 STKSGQEQIE 961
>gi|239750456 PREDICTED: similar to KIAA0655 protein [Homo sapiens]
Length = 1048
Score = 108 bits (269), Expect = 9e-23
Identities = 73/241 (30%), Positives = 130/241 (53%), Gaps = 12/241 (4%)
Query: 2297 VDPEDPTVIAETELLGAAASIEAAAKKLEQLKPRAKPKQADETLDFEEQILEAAKSIAAA 2356
V E+ + + E+ +A+IE A +++E + +A+ + L+ E+IL + + A
Sbjct: 754 VRQEELGAVVDKEMAATSAAIEDAVRRIEDMMNQARHASSGVKLEVNERILNSCTDLMKA 813
Query: 2357 TSALVKSASAAQRELVAQGKVGSIPANA-ADDGQWSQGLISAARMVAAATSSLCEAANAS 2415
LV ++++ Q+E+V G+ + A + +W++GLISA++ V + L EAA+
Sbjct: 814 IRLLVTTSTSLQKEIVESGRGAATQQEFYAKNSRWTEGLISASKAVGWGATQLVEAADKV 873
Query: 2416 VQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAAGNAVKRASDNLVRAA 2475
V E+LI + ++AASTAQL+ A KVKA++ S + RLQ V + N+V A+
Sbjct: 874 VLHTGKYEELIVCSHEIAASTAQLVAASKVKANKHSPHLSRLQECSRTVNERAANVV-AS 932
Query: 2476 QKAAFGKADDDDVVVKTKFVGGIAQIIAAQEEM------LKKERELEEARKKLAQIRQQQ 2529
K+ + +D D T G++ I ++EM L+ E+ LE R +L ++R+Q
Sbjct: 933 TKSGQEQIEDRD----TMDFSGLSLIKLKKQEMETQVRVLELEKTLEAERMRLGELRKQH 988
Query: 2530 Y 2530
Y
Sbjct: 989 Y 989
Score = 35.8 bits (81), Expect = 0.55
Identities = 45/190 (23%), Positives = 80/190 (42%), Gaps = 25/190 (13%)
Query: 590 MSKGVKLLAALMDDEVGSGEDLLRAARTLAGAV------------SDLLKAVQ--PTSGE 635
+ K + +A ++D V ED++ AR + V +DL+KA++ T+
Sbjct: 763 VDKEMAATSAAIEDAVRRIEDMMNQARHASSGVKLEVNERILNSCTDLMKAIRLLVTTST 822
Query: 636 PRQTVLTAAGSIGQASGDLLRQIGENETDERFQDVLMSLAKAVANAAAMLVLKAKNVAQV 695
Q + +G + + + R+ + L+S +KAV A LV A V
Sbjct: 823 SLQKEIVESGRGAATQQEFYAK------NSRWTEGLISASKAVGWGATQLVEAADKVVL- 875
Query: 696 AEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVR 755
T +I + + A ST+QLVA +KV + S + +L E + V+ N V
Sbjct: 876 --HTGKYEELIVCSHEIAASTAQLVAASKVKANKHSPHL--SRLQECSRTVNERAANVVA 931
Query: 756 ACQAATTDSE 765
+ ++ E
Sbjct: 932 STKSGQEQIE 941
>gi|13446229 mesoderm development candidate 1 [Homo sapiens]
Length = 362
Score = 100 bits (250), Expect = 1e-20
Identities = 75/307 (24%), Positives = 140/307 (45%), Gaps = 9/307 (2%)
Query: 1329 GAPNAKNLLAAAARAVTESINQ----LITLCTQ-QAPGQKECDNALRELETVKGMLDNPN 1383
G P + A A A+ + +Q L+++C + Q D L E + + P
Sbjct: 7 GKPTGEAASPAPASAIGGASSQPRKRLVSVCDHCKGKMQLVADLLLLSSEARPVLFEGPA 66
Query: 1384 EPVSDLSYFD-CIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAA 1442
+ F+ C ++++ +K L + G G+ + + LTE +
Sbjct: 67 SSGAGAESFEQCRDTIIARTKGLSILTHDVQSQLNMGRFGEAGDSLVELGDLVVSLTECS 126
Query: 1443 AQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNL-VDP--GSSPSQVLSAATI 1499
A AAYL ++ P +Q GLVD + R ++ C L P +P +L +
Sbjct: 127 AHAAYLAAVATPGAQPAQPGLVDRYRVTRCRHEVEQGCAVLRATPLADMTPQLLLEVSQG 186
Query: 1500 VAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNK 1559
++++ L +AC +AS K+ + ++ F K ++ S + L+ ++ + SE R++
Sbjct: 187 LSRNLKFLTDACALASDKSRDRFSREQFKLGVKCMSTSASALLACVREVKVAPSELARSR 246
Query: 1560 CRIATAPLIEAVENLTAFASNPEFVSIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTA 1619
C + + PL++AV L FA+ P+F+ A +S+EG Q IL A +++ + L +
Sbjct: 247 CALFSGPLVQAVSALVGFATEPQFLGRAAAVSAEGKAVQTAILGGAMSVVSACVLLTQCL 306
Query: 1620 RSLAINP 1626
R LA +P
Sbjct: 307 RDLAQHP 313
Score = 35.4 bits (80), Expect = 0.72
Identities = 33/155 (21%), Positives = 65/155 (41%), Gaps = 13/155 (8%)
Query: 1824 LVGGMVDAIAEAMSKLDEGTPPEPKG--TFVDYQTTVVKYSKAIAVTAQEMMTK------ 1875
LV ++ +EA L EG G +F + T++ +K +++ ++ ++
Sbjct: 46 LVADLLLLSSEARPVLFEGPASSGAGAESFEQCRDTIIARTKGLSILTHDVQSQLNMGRF 105
Query: 1876 --SVTNPEELGGLASQMTSDYGHLAFQGQMAAATAEPEEIGFQIRTRVQDLGHGCIFLVQ 1933
+ + ELG L +T H A+ +A A+P + G R RV H + Q
Sbjct: 106 GEAGDSLVELGDLVVSLTECSAHAAYLAAVATPGAQPAQPGLVDRYRVTRCRHE---VEQ 162
Query: 1934 KAGALQVCPTDSYTKRELIECARAVTEKVSLVLSA 1968
L+ P T + L+E ++ ++ + + A
Sbjct: 163 GCAVLRATPLADMTPQLLLEVSQGLSRNLKFLTDA 197
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 66.6 bits (161), Expect = 3e-10
Identities = 55/243 (22%), Positives = 112/243 (46%), Gaps = 14/243 (5%)
Query: 175 WLDHSRTFREQGVDENETLLL--RRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPV 232
WL ++ +Q V + L R KFF D + + + L ++Q ++ ILN
Sbjct: 58 WLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYC 117
Query: 233 SFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGA-----EKRIFQEHK 287
E A + Q ++G + + HKPG+L LP+ ++Q E+RI H+
Sbjct: 118 PPETAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHE 177
Query: 288 NCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKT 347
M ++ ++Y+K+A+ L YGV++F +K K + L LG+ ++ D+K
Sbjct: 178 EHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGL---NIYEHDDKL 234
Query: 348 KEVLQEWPLTTVKRWAASPKSFT---LDFGEYQESYYSVQTTEGEQISQLIAGYIDIILK 404
+ +P + ++ + + K F +D +Y+ + ++I L G ++ ++
Sbjct: 235 TPKI-GFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMR 293
Query: 405 KKQ 407
+++
Sbjct: 294 RRK 296
>gi|40254949 erythrocyte membrane protein band 4.1 like 5 [Homo
sapiens]
Length = 733
Score = 65.9 bits (159), Expect = 5e-10
Identities = 50/186 (26%), Positives = 86/186 (46%), Gaps = 10/186 (5%)
Query: 174 NWLDHSRTFREQ-GVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPV 232
+WLD +++ ++Q + L LR KF+ S+ N + R+ + L +Q + DIL+G
Sbjct: 96 HWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPN-NLREELTRYLFVLQLKQDILSGKLDC 154
Query: 233 SFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEM 292
F+ A + + Q + G + +H P + F+P I+ E IF++ K
Sbjct: 155 PFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVP---IQTEEMELAIFEKWKEYRGQ 211
Query: 293 SEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQ 352
+ +A+ Y+ A+ L YGV +VK + LG+T V+ + TK L
Sbjct: 212 TPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYS-----LGLTPTGVLVFEGDTKIGLF 266
Query: 353 EWPLTT 358
WP T
Sbjct: 267 FWPKIT 272
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 64.3 bits (155), Expect = 1e-09
Identities = 58/217 (26%), Positives = 103/217 (47%), Gaps = 13/217 (5%)
Query: 206 VDSRDPVQLNLL-YVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDL 264
V +DP+ ++ Y Q L G H + E+ + G +++F + + P L
Sbjct: 2002 VPGKDPMADSIFHYYQELPKYLRGYHKCTREEVLQLGALIYRVKF--EEDKSYFPSIPKL 2059
Query: 265 -KEFLPKEYIKQRGAE--KR--IFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVK 319
+E +P++ I+Q + KR + +K+ G+ E EAK+ ++KL T+G +FF VK
Sbjct: 2060 LRELVPQDLIRQVSPDDWKRSIVAYFNKHAGKSKE-EAKLAFLKLIFKWPTFGSAFFEVK 2118
Query: 320 EKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGE-YQE 378
+ + + L+ I K V +D KTK++L P T + W++ F + G +
Sbjct: 2119 QTTEPNFPEI-LLIAINKYGVSLIDPKTKDILTTHPFTKISNWSSGNTYFHITIGNLVRG 2177
Query: 379 SYYSVQTTEGEQISQLIAGYIDIIL--KKKQSKDRFG 413
S +T+ G ++ L+ YI +L KQ R G
Sbjct: 2178 SKLLCETSLGYKMDDLLTSYISQMLTAMSKQRGSRSG 2214
>gi|110624794 erythrocyte membrane protein band 4.1 like 4B isoform
1 [Homo sapiens]
Length = 518
Score = 64.3 bits (155), Expect = 1e-09
Identities = 50/186 (26%), Positives = 82/186 (44%), Gaps = 10/186 (5%)
Query: 174 NWLDHSRTFREQ-GVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPV 232
+WLDH++ ++Q + L R K++ S+ N + R+ L +Q R DIL+G
Sbjct: 138 HWLDHAKPIKKQMKIGPAYALHFRVKYYSSEPN-NLREEFTRYLFVLQLRHDILSGKLKC 196
Query: 233 SFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEM 292
+E A E Q + G +H P + F+P + E IFQ K C
Sbjct: 197 PYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQ---TEAMEFDIFQRWKECRGK 253
Query: 293 SEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQ 352
S +A++ Y+ A+ L YGV +V+ + + LG+T ++ + K L
Sbjct: 254 SPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYS-----LGLTPTGILIFEGANKIGLF 308
Query: 353 EWPLTT 358
WP T
Sbjct: 309 FWPKIT 314
>gi|110624790 erythrocyte membrane protein band 4.1 like 4B isoform
2 [Homo sapiens]
Length = 900
Score = 64.3 bits (155), Expect = 1e-09
Identities = 50/186 (26%), Positives = 82/186 (44%), Gaps = 10/186 (5%)
Query: 174 NWLDHSRTFREQ-GVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPV 232
+WLDH++ ++Q + L R K++ S+ N + R+ L +Q R DIL+G
Sbjct: 138 HWLDHAKPIKKQMKIGPAYALHFRVKYYSSEPN-NLREEFTRYLFVLQLRHDILSGKLKC 196
Query: 233 SFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEM 292
+E A E Q + G +H P + F+P + E IFQ K C
Sbjct: 197 PYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQ---TEAMEFDIFQRWKECRGK 253
Query: 293 SEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQ 352
S +A++ Y+ A+ L YGV +V+ + + LG+T ++ + K L
Sbjct: 254 SPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYS-----LGLTPTGILIFEGANKIGLF 308
Query: 353 EWPLTT 358
WP T
Sbjct: 309 FWPKIT 314
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 62.8 bits (151), Expect = 4e-09
Identities = 41/154 (26%), Positives = 73/154 (47%), Gaps = 7/154 (4%)
Query: 175 WLDHSRTFREQGVDENETLLL--RRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPV 232
WL ++ Q V + LL R KF+ D + + + L ++Q ++ ILN
Sbjct: 58 WLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYC 117
Query: 233 SFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQE-----HK 287
E A + Q ++G + HK G+L + LP+ ++Q K ++E H+
Sbjct: 118 PPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHE 177
Query: 288 NCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEK 321
M +A ++Y+K+A+ L YGV++F +K K
Sbjct: 178 EHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNK 211
>gi|29789006 fermitin family homolog 2 isoform 1 [Homo sapiens]
Length = 680
Score = 62.8 bits (151), Expect = 4e-09
Identities = 36/143 (25%), Positives = 76/143 (53%), Gaps = 7/143 (4%)
Query: 270 KEYIKQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLV 329
K+Y K + RI + H+N +MS IEAK+++++ +SL +G++ F+ + +G K
Sbjct: 528 KKY-KNKQITARILEAHQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIA--RFQGGKK-- 582
Query: 330 PRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAAS--PKSFTLDFGEYQESYYSVQTTE 387
L+GI + ++R+D T + ++ W + +K+W + K T++F + + +
Sbjct: 583 EELIGIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMVTVEFADEVRLSFICTEVD 642
Query: 388 GEQISQLIAGYIDIILKKKQSKD 410
+ + + I GYI + + K +
Sbjct: 643 CKVVHEFIGGYIFLSTRAKDQNE 665
Score = 45.8 bits (107), Expect = 5e-04
Identities = 31/84 (36%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
Query: 164 KAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARD 223
KAK++ WLD SR+ EQ V ENE LLLR K++ D +++N LY QA+
Sbjct: 245 KAKINQ----GWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQAKW 300
Query: 224 DILNGSHPVSFEKACEFGGFQAQI 247
IL + E+ F Q I
Sbjct: 301 AILLEEIECTEEEMMMFAALQYHI 324
>gi|87042275 erythrocyte protein band 4.1-like 4 [Homo sapiens]
Length = 686
Score = 62.4 bits (150), Expect = 6e-09
Identities = 50/188 (26%), Positives = 82/188 (43%), Gaps = 13/188 (6%)
Query: 175 WLDHSRTFREQGVDENE----TLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSH 230
WLD ++T E N TL KF Y++ ++ + ++Q + D+L G
Sbjct: 70 WLDPAKTLAEHKELINTGPPYTLYFGIKF-YAEDPCKLKEEITRYQFFLQVKQDVLQGRL 128
Query: 231 PVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCG 290
P A + G + Q + G + +KH G++ F+P + + A +RI HK
Sbjct: 129 PCPVNTAAQLGAYAIQSELGDYDPYKHTAGYVSEYRFVPDQKEELEEAIERI---HKTLM 185
Query: 291 EMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEV 350
EA++ Y++ A+SL YGV + G+NK LG+T V+ K +
Sbjct: 186 GQIPSEAELNYLRTAKSLEMYGVDL----HPVYGENK-SEYFLGLTPVGVVVYKNKKQVG 240
Query: 351 LQEWPLTT 358
WP T
Sbjct: 241 KYFWPRIT 248
>gi|30061491 erythrocyte membrane protein band 4.1-like 1 isoform b
[Homo sapiens]
Length = 779
Score = 62.0 bits (149), Expect = 7e-09
Identities = 49/209 (23%), Positives = 89/209 (42%), Gaps = 9/209 (4%)
Query: 170 DDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGS 229
D NWLD S+ ++Q KF+ D + D + L +Q R DI+ G
Sbjct: 84 DSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTED-ITRYYLCLQLRADIITGR 142
Query: 230 HPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNC 289
P SF G + Q + G + +H ++ F P + R E+RI + HK
Sbjct: 143 LPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQ---TRELEERIMELHKTY 199
Query: 290 GEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKE 349
M+ EA++ +++ A+ L YGV K+ ++ + +LG+ + ++ ++ +
Sbjct: 200 RGMTPGEAEIHFLENAKKLSMYGVDLHHAKD-----SEGIDIMLGVCANGLLIYRDRLRI 254
Query: 350 VLQEWPLTTVKRWAASPKSFTLDFGEYQE 378
WP + S + GEY++
Sbjct: 255 NRFAWPKILKISYKRSNFYIKIRPGEYEQ 283
>gi|30061489 erythrocyte membrane protein band 4.1-like 1 isoform a
[Homo sapiens]
Length = 881
Score = 62.0 bits (149), Expect = 7e-09
Identities = 49/209 (23%), Positives = 89/209 (42%), Gaps = 9/209 (4%)
Query: 170 DDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGS 229
D NWLD S+ ++Q KF+ D + D + L +Q R DI+ G
Sbjct: 146 DSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTED-ITRYYLCLQLRADIITGR 204
Query: 230 HPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNC 289
P SF G + Q + G + +H ++ F P + R E+RI + HK
Sbjct: 205 LPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQ---TRELEERIMELHKTY 261
Query: 290 GEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKE 349
M+ EA++ +++ A+ L YGV K+ ++ + +LG+ + ++ ++ +
Sbjct: 262 RGMTPGEAEIHFLENAKKLSMYGVDLHHAKD-----SEGIDIMLGVCANGLLIYRDRLRI 316
Query: 350 VLQEWPLTTVKRWAASPKSFTLDFGEYQE 378
WP + S + GEY++
Sbjct: 317 NRFAWPKILKISYKRSNFYIKIRPGEYEQ 345
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 61.6 bits (148), Expect = 9e-09
Identities = 58/217 (26%), Positives = 101/217 (46%), Gaps = 15/217 (6%)
Query: 206 VDSRDPVQLNLL-YVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDL 264
V +DP+ ++ Y Q L G H + E+ + G +++F + + P L
Sbjct: 1964 VPGKDPMADSIFHYYQELPKYLRGYHKCTREEVLQLGALIYRVKF--EEDKSYFPSIPKL 2021
Query: 265 -KEFLPKEYIKQRGAE--KR--IFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVK 319
+E +P++ I+Q + KR + +K+ G+ E EAK+ ++KL T+G +FF
Sbjct: 2022 LRELVPQDLIRQVSPDDWKRSIVAYFNKHAGKSKE-EAKLAFLKLIFKWPTFGSAFF--- 2077
Query: 320 EKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGE-YQE 378
E+ N L+ I K V +D KTK++L P T + W++ F + G +
Sbjct: 2078 EQTTEPNFPEILLIAINKYGVSLIDPKTKDILTTHPFTKISNWSSGNTYFHITIGNLVRG 2137
Query: 379 SYYSVQTTEGEQISQLIAGYIDIIL--KKKQSKDRFG 413
S +T+ G ++ L+ YI +L KQ R G
Sbjct: 2138 SKLLCETSLGYKMDDLLTSYISQMLTAMSKQRGSRSG 2174
>gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Homo
sapiens]
Length = 926
Score = 61.6 bits (148), Expect = 9e-09
Identities = 43/152 (28%), Positives = 72/152 (47%), Gaps = 5/152 (3%)
Query: 171 DDLNWLDHSRTFREQGVDENE-TLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGS 229
D+ WLD ++ R+Q + +L R KFF SD N + + ++Q + DIL G
Sbjct: 80 DNPRWLDPNKPIRKQLKRGSPYSLNFRVKFFVSDPNKLQEEYTRYQY-FLQIKQDILTGR 138
Query: 230 HPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNC 289
P A F Q + G + + ++ G+L F+P + + EK I + H+
Sbjct: 139 LPCPSNTAALLASFAVQSELGDYDQSENLSGYLSDYSFIPNQ---PQDFEKEIAKLHQQH 195
Query: 290 GEMSEIEAKVKYVKLARSLRTYGVSFFLVKEK 321
+S EA+ Y+ AR+L YGV F +++
Sbjct: 196 IGLSPAEAEFNYLNTARTLELYGVEFHYARDQ 227
>gi|201861813 fermitin family homolog 2 isoform 2 [Homo sapiens]
Length = 687
Score = 61.6 bits (148), Expect = 9e-09
Identities = 33/132 (25%), Positives = 71/132 (53%), Gaps = 6/132 (4%)
Query: 281 RIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSV 340
RI + H+N +MS IEAK+++++ +SL +G++ F+ + +G K L+GI + +
Sbjct: 545 RILEAHQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIA--RFQGGKK--EELIGIAYNRL 600
Query: 341 MRVDEKTKEVLQEWPLTTVKRWAAS--PKSFTLDFGEYQESYYSVQTTEGEQISQLIAGY 398
+R+D T + ++ W + +K+W + K T++F + + + + + + I GY
Sbjct: 601 IRMDASTGDAIKTWRFSNMKQWNVNWEIKMVTVEFADEVRLSFICTEVDCKVVHEFIGGY 660
Query: 399 IDIILKKKQSKD 410
I + + K +
Sbjct: 661 IFLSTRAKDQNE 672
Score = 45.8 bits (107), Expect = 5e-04
Identities = 31/84 (36%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
Query: 164 KAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARD 223
KAK++ WLD SR+ EQ V ENE LLLR K++ D +++N LY QA+
Sbjct: 245 KAKINQ----GWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQAKW 300
Query: 224 DILNGSHPVSFEKACEFGGFQAQI 247
IL + E+ F Q I
Sbjct: 301 AILLEEIECTEEEMMMFAALQYHI 324
>gi|161702986 ezrin [Homo sapiens]
Length = 586
Score = 61.2 bits (147), Expect = 1e-08
Identities = 54/243 (22%), Positives = 107/243 (44%), Gaps = 14/243 (5%)
Query: 175 WLDHSRTFREQGVDENETLLL--RRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPV 232
WL + Q V + L R KF+ D + + L ++Q ++ IL+
Sbjct: 58 WLKLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYC 117
Query: 233 SFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGA-----EKRIFQEHK 287
E A G + Q +FG + + HK G+L + +P+ + Q E RI H
Sbjct: 118 PPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHA 177
Query: 288 NCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKT 347
M + A ++Y+K+A+ L YG+++F +K K L LG+ ++ D+K
Sbjct: 178 EHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGL---NIYEKDDKL 234
Query: 348 KEVLQEWPLTTVKRWAASPKSFT---LDFGEYQESYYSVQTTEGEQISQLIAGYIDIILK 404
+ +P + ++ + + K F +D +Y+ + ++I QL G ++ ++
Sbjct: 235 TPKI-GFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMR 293
Query: 405 KKQ 407
+++
Sbjct: 294 RRK 296
Score = 32.7 bits (73), Expect = 4.7
Identities = 38/171 (22%), Positives = 66/171 (38%), Gaps = 9/171 (5%)
Query: 2307 ETELLGAAASIEAAAKKLEQLKPRAKPKQADETLDFEEQILEAAKSIAAATSALVKSASA 2366
E + + A A E K+LE+ + + K+ + +EQ++ + + +
Sbjct: 301 EVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKK 360
Query: 2367 AQRELVAQGKVGSIPANAADDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLI 2426
A+REL Q + Q + A RM A E +V S+E+L
Sbjct: 361 AERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKE--ELERQAVDQIKSQEQLA 418
Query: 2427 SSAKQVAASTAQLLVACKVKADQDSEAMRRLQAAGNAVKRASDNLVRAAQK 2477
+ + A A L A + K D+ E R K A D+LV+ ++
Sbjct: 419 AELAEYTAKIALLEEARRRKEDEVEEWQHR-------AKEAQDDLVKTKEE 462
>gi|21614499 ezrin [Homo sapiens]
Length = 586
Score = 61.2 bits (147), Expect = 1e-08
Identities = 54/243 (22%), Positives = 107/243 (44%), Gaps = 14/243 (5%)
Query: 175 WLDHSRTFREQGVDENETLLL--RRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPV 232
WL + Q V + L R KF+ D + + L ++Q ++ IL+
Sbjct: 58 WLKLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYC 117
Query: 233 SFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGA-----EKRIFQEHK 287
E A G + Q +FG + + HK G+L + +P+ + Q E RI H
Sbjct: 118 PPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHA 177
Query: 288 NCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKT 347
M + A ++Y+K+A+ L YG+++F +K K L LG+ ++ D+K
Sbjct: 178 EHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGL---NIYEKDDKL 234
Query: 348 KEVLQEWPLTTVKRWAASPKSFT---LDFGEYQESYYSVQTTEGEQISQLIAGYIDIILK 404
+ +P + ++ + + K F +D +Y+ + ++I QL G ++ ++
Sbjct: 235 TPKI-GFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMR 293
Query: 405 KKQ 407
+++
Sbjct: 294 RRK 296
Score = 32.7 bits (73), Expect = 4.7
Identities = 38/171 (22%), Positives = 66/171 (38%), Gaps = 9/171 (5%)
Query: 2307 ETELLGAAASIEAAAKKLEQLKPRAKPKQADETLDFEEQILEAAKSIAAATSALVKSASA 2366
E + + A A E K+LE+ + + K+ + +EQ++ + + +
Sbjct: 301 EVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKK 360
Query: 2367 AQRELVAQGKVGSIPANAADDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLI 2426
A+REL Q + Q + A RM A E +V S+E+L
Sbjct: 361 AERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKE--ELERQAVDQIKSQEQLA 418
Query: 2427 SSAKQVAASTAQLLVACKVKADQDSEAMRRLQAAGNAVKRASDNLVRAAQK 2477
+ + A A L A + K D+ E R K A D+LV+ ++
Sbjct: 419 AELAEYTAKIALLEEARRRKEDEVEEWQHR-------AKEAQDDLVKTKEE 462
>gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 60.8 bits (146), Expect = 2e-08
Identities = 56/252 (22%), Positives = 113/252 (44%), Gaps = 22/252 (8%)
Query: 171 DDLNWLDHSRTFREQGVDENE--TLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNG 228
D + WL + + V + E T KF+ + + + +L ++Q + IL+
Sbjct: 70 DTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDE 129
Query: 229 SHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIK-----QRGAEKRI- 282
E + + Q ++G + HK GFL +E LPK I E+RI
Sbjct: 130 KIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERIT 189
Query: 283 --FQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSV 340
+ EH+ + EA+++Y+K+A+ L YGV++F ++ K K LLG+ +
Sbjct: 190 AWYAEHRG---RARDEAEMEYLKIAQDLEMYGVNYFAIRNK-----KGTELLLGVDALGL 241
Query: 341 MRVDEKTKEVLQ-EWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTE---GEQISQLIA 396
D + + + +P ++ + S K FT+ + + + +++ + I QL
Sbjct: 242 HIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCI 301
Query: 397 GYIDIILKKKQS 408
G D+ ++++++
Sbjct: 302 GNHDLFMRRRKA 313
>gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 60.8 bits (146), Expect = 2e-08
Identities = 56/252 (22%), Positives = 113/252 (44%), Gaps = 22/252 (8%)
Query: 171 DDLNWLDHSRTFREQGVDENE--TLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNG 228
D + WL + + V + E T KF+ + + + +L ++Q + IL+
Sbjct: 70 DTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDE 129
Query: 229 SHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIK-----QRGAEKRI- 282
E + + Q ++G + HK GFL +E LPK I E+RI
Sbjct: 130 KIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERIT 189
Query: 283 --FQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSV 340
+ EH+ + EA+++Y+K+A+ L YGV++F ++ K K LLG+ +
Sbjct: 190 AWYAEHRG---RARDEAEMEYLKIAQDLEMYGVNYFAIRNK-----KGTELLLGVDALGL 241
Query: 341 MRVDEKTKEVLQ-EWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTE---GEQISQLIA 396
D + + + +P ++ + S K FT+ + + + +++ + I QL
Sbjct: 242 HIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCI 301
Query: 397 GYIDIILKKKQS 408
G D+ ++++++
Sbjct: 302 GNHDLFMRRRKA 313
>gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 60.8 bits (146), Expect = 2e-08
Identities = 56/252 (22%), Positives = 113/252 (44%), Gaps = 22/252 (8%)
Query: 171 DDLNWLDHSRTFREQGVDENE--TLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNG 228
D + WL + + V + E T KF+ + + + +L ++Q + IL+
Sbjct: 70 DTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDE 129
Query: 229 SHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIK-----QRGAEKRI- 282
E + + Q ++G + HK GFL +E LPK I E+RI
Sbjct: 130 KIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERIT 189
Query: 283 --FQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSV 340
+ EH+ + EA+++Y+K+A+ L YGV++F ++ K K LLG+ +
Sbjct: 190 AWYAEHRG---RARDEAEMEYLKIAQDLEMYGVNYFAIRNK-----KGTELLLGVDALGL 241
Query: 341 MRVDEKTKEVLQ-EWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTE---GEQISQLIA 396
D + + + +P ++ + S K FT+ + + + +++ + I QL
Sbjct: 242 HIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCI 301
Query: 397 GYIDIILKKKQS 408
G D+ ++++++
Sbjct: 302 GNHDLFMRRRKA 313
>gi|4557795 neurofibromin 2 isoform 1 [Homo sapiens]
Length = 595
Score = 60.8 bits (146), Expect = 2e-08
Identities = 56/252 (22%), Positives = 113/252 (44%), Gaps = 22/252 (8%)
Query: 171 DDLNWLDHSRTFREQGVDENE--TLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNG 228
D + WL + + V + E T KF+ + + + +L ++Q + IL+
Sbjct: 70 DTVAWLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDE 129
Query: 229 SHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIK-----QRGAEKRI- 282
E + + Q ++G + HK GFL +E LPK I E+RI
Sbjct: 130 KIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERIT 189
Query: 283 --FQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSV 340
+ EH+ + EA+++Y+K+A+ L YGV++F ++ K K LLG+ +
Sbjct: 190 AWYAEHRG---RARDEAEMEYLKIAQDLEMYGVNYFAIRNK-----KGTELLLGVDALGL 241
Query: 341 MRVDEKTKEVLQ-EWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTE---GEQISQLIA 396
D + + + +P ++ + S K FT+ + + + +++ + I QL
Sbjct: 242 HIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCI 301
Query: 397 GYIDIILKKKQS 408
G D+ ++++++
Sbjct: 302 GNHDLFMRRRKA 313
>gi|116686114 kindlin-1 [Homo sapiens]
Length = 677
Score = 60.5 bits (145), Expect = 2e-08
Identities = 31/139 (22%), Positives = 75/139 (53%), Gaps = 6/139 (4%)
Query: 274 KQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLL 333
K + RI + H+N +M +EAK+++++ +SL +G++++LV + KG K +L
Sbjct: 528 KSKQLAARILEAHQNVAQMPLVEAKLRFIQAWQSLPEFGLTYYLV--RFKGSKK--DDIL 583
Query: 334 GITKDSVMRVDEKTKEVLQEWPLTTVKRWAAS--PKSFTLDFGEYQESYYSVQTTEGEQI 391
G++ + ++++D T + W T +K+W + + ++F + + ++ + + + +
Sbjct: 584 GVSYNRLIKIDAATGIPVTTWRFTNIKQWNVNWETRQVVIEFDQNVFTAFTCLSADCKIV 643
Query: 392 SQLIAGYIDIILKKKQSKD 410
+ I GYI + + K +
Sbjct: 644 HEYIGGYIFLSTRSKDQNE 662
Score = 48.5 bits (114), Expect = 8e-05
Identities = 33/84 (39%), Positives = 43/84 (51%), Gaps = 4/84 (4%)
Query: 164 KAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARD 223
KAKL+ WLD SR+ EQG+ E+E LLLR K++ D V++N LY QAR
Sbjct: 243 KAKLNA----GWLDSSRSLMEQGIQEDEQLLLRFKYYSFFDLNPKYDAVRINQLYEQARW 298
Query: 224 DILNGSHPVSFEKACEFGGFQAQI 247
IL + E+ F Q I
Sbjct: 299 AILLEEIDCTEEEMLIFAALQYHI 322
>gi|42716289 erythrocyte membrane protein band 4.1 (elliptocytosis
1, RH-linked) isoform 1 [Homo sapiens]
Length = 775
Score = 60.1 bits (144), Expect = 3e-08
Identities = 62/265 (23%), Positives = 110/265 (41%), Gaps = 24/265 (9%)
Query: 127 EEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDL-------NWLDHS 179
EE S I+ E + + LK + +R R M K+ DD WLD +
Sbjct: 177 EECSKIEVKEESPQSKAETELKASQKPIRKHRNMH---CKVSLLDDTVYECVVETWLDSA 233
Query: 180 RTFREQ--GVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKA 237
+ ++Q GV N T ++ FY + + L +Q R DI+ G P SF
Sbjct: 234 KEIKKQVRGVPWNFTFNVK---FYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATL 290
Query: 238 CEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEA 297
G + Q + G + H ++ + P + + E+++ + HK+ M+ +A
Sbjct: 291 ALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQ---TKELEEKVMELHKSYRSMTPAQA 347
Query: 298 KVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLT 357
+++++ A+ L YGV K+ ++G V +LG+ ++ +K + WP
Sbjct: 348 DLEFLENAKKLSMYGVDLHKAKD-LEG----VDIILGVCSSGLLVYKDKLRINRFPWPKV 402
Query: 358 TVKRWAASPKSFTLDFGEYQESYYS 382
+ S + GE QE Y S
Sbjct: 403 LKISYKRSSFFIKIRPGE-QEQYES 426
>gi|28626504 fermitin family homolog 3 short form [Homo sapiens]
Length = 663
Score = 58.9 bits (141), Expect = 6e-08
Identities = 31/135 (22%), Positives = 73/135 (54%), Gaps = 6/135 (4%)
Query: 274 KQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLL 333
K + RI + H+N ++S EA++++++ +SL +G+S+ +V + KG K +L
Sbjct: 512 KAKQLTPRILEAHQNVAQLSLAEAQLRFIQAWQSLPDFGISYVMV--RFKGSRK--DEIL 567
Query: 334 GITKDSVMRVDEKTKEVLQEWPLTTVKRWAAS--PKSFTLDFGEYQESYYSVQTTEGEQI 391
GI + ++R+D +V++ W + +++W + + ++F E+ +S + +
Sbjct: 568 GIANNRLIRIDLAVGDVVKTWRFSNMRQWNVNWDIRQVAIEFDEHINVAFSCVSASCRIV 627
Query: 392 SQLIAGYIDIILKKK 406
+ I GYI + +++
Sbjct: 628 HEYIGGYIFLSTRER 642
Score = 46.2 bits (108), Expect = 4e-04
Identities = 74/285 (25%), Positives = 112/285 (39%), Gaps = 76/285 (26%)
Query: 34 IRERVPEAQ------TGQASDYGLFLS--DEDPRK------GIWLEAGR--------TLD 71
+ E PEA+ TG++ G+ L ++ RK IW E R TLD
Sbjct: 22 VGEEDPEAESVTLRVTGESHIGGVLLKIVEQINRKQDWSDHAIWWEQKRQWLLQTHWTLD 81
Query: 72 YYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSL 131
Y + L + + RP +R+ + + S+ + + + IC + I + EE SL
Sbjct: 82 KYGILADARLFFGPQHRPVILRLPNRRALRLRASFSQPLFQAVAAICRLLSIRHPEELSL 141
Query: 132 IQ--ETIEEKK-----EEGTGTLKK----------------------------------- 149
++ E E+KK EE L K
Sbjct: 142 LRAPEKKEKKKKEKEPEEELYDLSKVVLAGGVAPALFRGMPAHFSDSAQTEACYHMLSRP 201
Query: 150 ----DRTLLRDERKMEKL--KAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSD 203
D LL+ + L K +LH+ WLD SR +QG+ + L LR K +YS
Sbjct: 202 QPPPDPLLLQRLPRPSSLSDKTQLHS----RWLDSSRCLMQQGIKAGDALWLRFK-YYSF 256
Query: 204 QNVDSR-DPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQI 247
++D + DPV+L LY QAR D+L + E+ F Q I
Sbjct: 257 FDLDPKTDPVRLTQLYEQARWDLLLEEIDCTEEEMMVFAALQYHI 301
>gi|41281905 fermitin family homolog 3 long form [Homo sapiens]
Length = 667
Score = 58.9 bits (141), Expect = 6e-08
Identities = 31/135 (22%), Positives = 73/135 (54%), Gaps = 6/135 (4%)
Query: 274 KQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLL 333
K + RI + H+N ++S EA++++++ +SL +G+S+ +V + KG K +L
Sbjct: 516 KAKQLTPRILEAHQNVAQLSLAEAQLRFIQAWQSLPDFGISYVMV--RFKGSRK--DEIL 571
Query: 334 GITKDSVMRVDEKTKEVLQEWPLTTVKRWAAS--PKSFTLDFGEYQESYYSVQTTEGEQI 391
GI + ++R+D +V++ W + +++W + + ++F E+ +S + +
Sbjct: 572 GIANNRLIRIDLAVGDVVKTWRFSNMRQWNVNWDIRQVAIEFDEHINVAFSCVSASCRIV 631
Query: 392 SQLIAGYIDIILKKK 406
+ I GYI + +++
Sbjct: 632 HEYIGGYIFLSTRER 646
Score = 46.2 bits (108), Expect = 4e-04
Identities = 74/285 (25%), Positives = 112/285 (39%), Gaps = 76/285 (26%)
Query: 34 IRERVPEAQ------TGQASDYGLFLS--DEDPRK------GIWLEAGR--------TLD 71
+ E PEA+ TG++ G+ L ++ RK IW E R TLD
Sbjct: 22 VGEEDPEAESVTLRVTGESHIGGVLLKIVEQINRKQDWSDHAIWWEQKRQWLLQTHWTLD 81
Query: 72 YYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSL 131
Y + L + + RP +R+ + + S+ + + + IC + I + EE SL
Sbjct: 82 KYGILADARLFFGPQHRPVILRLPNRRALRLRASFSQPLFQAVAAICRLLSIRHPEELSL 141
Query: 132 IQ--ETIEEKK-----EEGTGTLKK----------------------------------- 149
++ E E+KK EE L K
Sbjct: 142 LRAPEKKEKKKKEKEPEEELYDLSKVVLAGGVAPALFRGMPAHFSDSAQTEACYHMLSRP 201
Query: 150 ----DRTLLRDERKMEKL--KAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSD 203
D LL+ + L K +LH+ WLD SR +QG+ + L LR K +YS
Sbjct: 202 QPPPDPLLLQRLPRPSSLSDKTQLHS----RWLDSSRCLMQQGIKAGDALWLRFK-YYSF 256
Query: 204 QNVDSR-DPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQI 247
++D + DPV+L LY QAR D+L + E+ F Q I
Sbjct: 257 FDLDPKTDPVRLTQLYEQARWDLLLEEIDCTEEEMMVFAALQYHI 301
>gi|223941879 protein tyrosine phosphatase, non-receptor type 3
isoform 2 [Homo sapiens]
Length = 868
Score = 58.2 bits (139), Expect = 1e-07
Identities = 57/237 (24%), Positives = 93/237 (39%), Gaps = 46/237 (19%)
Query: 84 KKKQRPQ---KIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQETIEEKK 140
K+K R + I LDG V+T V T LL + + +G+T E + L
Sbjct: 22 KEKTRSEVICSIHFLDGVVQTFKVTKQDTGQVLLDMVHNHLGVTEKEYFGL--------- 72
Query: 141 EEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLN---WLDHSRTFREQGVDENE-TLLLR 196
H DD ++ WL+ S+ R+Q TL R
Sbjct: 73 --------------------------QHDDDSVDSPRWLEASKAIRKQLKGGFPCTLHFR 106
Query: 197 RKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHK 256
+FF D N ++ + +L ++Q + DI G A + Q FG +
Sbjct: 107 VRFFIPDPNTLQQEQTR-HLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSI 165
Query: 257 HKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGV 313
H PG+L F+P + + + ++H + + EA+ Y+ +AR+L YGV
Sbjct: 166 HHPGYLSDSHFIPDQNEDFLTKVESLHEQHSG---LKQSEAESCYINIARTLDFYGV 219
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.125 0.337
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,299,240
Number of Sequences: 37866
Number of extensions: 3171868
Number of successful extensions: 10566
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 154
Number of HSP's that attempted gapping in prelim test: 9879
Number of HSP's gapped (non-prelim): 669
length of query: 2542
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2423
effective length of database: 13,741,464
effective search space: 33295567272
effective search space used: 33295567272
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.