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Search of human proteins with 156627577
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156627577 transglutaminase 4 (prostate) [Homo sapiens]
(684 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156627577 transglutaminase 4 (prostate) [Homo sapiens] 1390 0.0
gi|4507475 transglutaminase 1 [Homo sapiens] 475 e-134
gi|16445035 transglutaminase 7 [Homo sapiens] 420 e-117
gi|148664232 transglutaminase 6 [Homo sapiens] 419 e-117
gi|119395709 coagulation factor XIII A1 subunit precursor [Homo ... 397 e-110
gi|189458821 transglutaminase 3 precursor [Homo sapiens] 390 e-108
gi|94981556 transglutaminase 5 isoform 1 [Homo sapiens] 386 e-107
gi|39777597 transglutaminase 2 isoform a [Homo sapiens] 360 2e-99
gi|39777599 transglutaminase 2 isoform b [Homo sapiens] 343 4e-94
gi|4759230 transglutaminase 5 isoform 2 [Homo sapiens] 333 2e-91
gi|166362735 erythrocyte membrane protein band 4.2 isoform 1 [Ho... 266 6e-71
gi|166362737 erythrocyte membrane protein band 4.2 isoform 2 [Ho... 265 8e-71
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 31 3.3
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 31 3.3
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 31 4.3
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 31 4.3
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 31 4.3
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 31 4.3
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom... 31 4.3
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom... 31 4.3
gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom... 31 4.3
gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens] 30 5.7
gi|66932941 XC chemokine receptor 1 [Homo sapiens] 30 5.7
gi|4885339 XC chemokine receptor 1 [Homo sapiens] 30 5.7
gi|221316650 ephrin receptor EphA1 [Homo sapiens] 30 7.4
gi|145977194 hypothetical protein LOC400793 isoform 2 [Homo sapi... 30 7.4
gi|207028635 hypothetical protein LOC400793 isoform 1 [Homo sapi... 30 7.4
gi|51173724 bystin [Homo sapiens] 30 7.4
gi|8922108 cytokine-like 1 [Homo sapiens] 30 7.4
gi|19923084 polycystin-1L1 [Homo sapiens] 30 7.4
>gi|156627577 transglutaminase 4 (prostate) [Homo sapiens]
Length = 684
Score = 1390 bits (3598), Expect = 0.0
Identities = 684/684 (100%), Positives = 684/684 (100%)
Query: 1 MMDASKELQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQLKL 60
MMDASKELQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQLKL
Sbjct: 1 MMDASKELQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQLKL 60
Query: 61 EFSTGPNPSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNV 120
EFSTGPNPSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNV
Sbjct: 61 EFSTGPNPSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNV 120
Query: 121 KTGNHILKSEENILYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWN 180
KTGNHILKSEENILYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWN
Sbjct: 121 KTGNHILKSEENILYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWN 180
Query: 181 FGQFEKNVLDCCISLLTESSLKPTDRRDPVLVCRAMCAMMSFEKGQGVLIGNWTGDYEGG 240
FGQFEKNVLDCCISLLTESSLKPTDRRDPVLVCRAMCAMMSFEKGQGVLIGNWTGDYEGG
Sbjct: 181 FGQFEKNVLDCCISLLTESSLKPTDRRDPVLVCRAMCAMMSFEKGQGVLIGNWTGDYEGG 240
Query: 241 TAPYKWTGSAPILQQYYNTKQAVCFGQCWVFAGILTTVLRALGIPARSVTGFDSAHDTER 300
TAPYKWTGSAPILQQYYNTKQAVCFGQCWVFAGILTTVLRALGIPARSVTGFDSAHDTER
Sbjct: 241 TAPYKWTGSAPILQQYYNTKQAVCFGQCWVFAGILTTVLRALGIPARSVTGFDSAHDTER 300
Query: 301 NLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATPQERSQGV 360
NLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATPQERSQGV
Sbjct: 301 NLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATPQERSQGV 360
Query: 361 FCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISMETTSIGKN 420
FCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISMETTSIGKN
Sbjct: 361 FCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISMETTSIGKN 420
Query: 421 ISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHAFLLLSSEREHRRPVKENFLHMSVQSD 480
ISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHAFLLLSSEREHRRPVKENFLHMSVQSD
Sbjct: 421 ISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHAFLLLSSEREHRRPVKENFLHMSVQSD 480
Query: 481 DVLLGNSVNFTVILKRKTAALQNVNILGSFELQLYTGKKMAKLCDLNKTSQIQGQVSEVT 540
DVLLGNSVNFTVILKRKTAALQNVNILGSFELQLYTGKKMAKLCDLNKTSQIQGQVSEVT
Sbjct: 481 DVLLGNSVNFTVILKRKTAALQNVNILGSFELQLYTGKKMAKLCDLNKTSQIQGQVSEVT 540
Query: 541 LTLDSKTYINSLAILDDEPVIRGFIIAEIVESKEIMASEVFTSFQYPEFSIELPNTGRIG 600
LTLDSKTYINSLAILDDEPVIRGFIIAEIVESKEIMASEVFTSFQYPEFSIELPNTGRIG
Sbjct: 541 LTLDSKTYINSLAILDDEPVIRGFIIAEIVESKEIMASEVFTSFQYPEFSIELPNTGRIG 600
Query: 601 QLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQTSDHGTVQPGETIQSQIKCTPIKTGPK 660
QLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQTSDHGTVQPGETIQSQIKCTPIKTGPK
Sbjct: 601 QLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQTSDHGTVQPGETIQSQIKCTPIKTGPK 660
Query: 661 KFIVKLSSKQVKEINAQKIVLITK 684
KFIVKLSSKQVKEINAQKIVLITK
Sbjct: 661 KFIVKLSSKQVKEINAQKIVLITK 684
>gi|4507475 transglutaminase 1 [Homo sapiens]
Length = 817
Score = 475 bits (1223), Expect = e-134
Identities = 248/665 (37%), Positives = 377/665 (56%), Gaps = 13/665 (1%)
Query: 17 NQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQLKLEFSTGPNPSIAKHTLV 76
+ N HHT E++ + RRGQ FH+ L+L++ +S ++ LE G NP + K T V
Sbjct: 122 SDQNRREHHTDEYEYDELIVRRGQPFHMLLLLSRTYESSDRITLELLIGNNPEVGKGTHV 181
Query: 77 VLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNVKTGNHILKSE-----E 131
++ P W+A + SG+ + + V +SPNAI+GK+Q V+T + + +
Sbjct: 182 II-PVGKGGSGGWKAQVVKASGQNLNLRVHTSPNAIIGKFQFTVRTQSDAGEFQLPFDPR 240
Query: 132 NILYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWNFGQFEKNVLDC 191
N +Y+LFNPWC ED+V++ ED R+EY+LN++G Y G I + WN+GQF+ VLD
Sbjct: 241 NEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDA 300
Query: 192 CISLLTESSLKPTDRRDPVLVCRAMCAMMSFEKGQGVLIGNWTGDYEGGTAPYKWTGSAP 251
C+ +L + R DPV V R + AM++ GVLIGNW+GDY GT P W GS
Sbjct: 301 CLYILDRRGMPYGGRGDPVNVSRVISAMVNSLDDNGVLIGNWSGDYSRGTNPSAWVGSVE 360
Query: 252 ILQQYYNTKQAVCFGQCWVFAGILTTVLRALGIPARSVTGFDSAHDTERNLTVDTYVNEN 311
IL Y T +V +GQCWVFAG+ TTVLR LG+ R+VT F+SAHDT+ +LT+D Y +EN
Sbjct: 361 ILLSYLRTGYSVPYGQCWVFAGVTTTVLRCLGLATRTVTNFNSAHDTDTSLTMDIYFDEN 420
Query: 312 GEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATPQERSQGVFCCGPSPLTAI 371
+ + + HDSVWNFHVW D WMKRPDLP G+DGWQ VDATPQE S G+FCCGP + +I
Sbjct: 421 MKPLEHLNHDSVWNFHVWNDCWMKRPDLPSGFDGWQVVDATPQETSSGIFCCGPCSVESI 480
Query: 372 RKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISMETTSIGKNISTKAVGQDRR 431
+ G +++ YDT F+F+EVN D++ W ++ +E +IG I TKA+ + R
Sbjct: 481 KNGLVYMKYDTPFIFAEVNSDKVYW---QRQDDGSFKIVYVEEKAIGTLIVTKAISSNMR 537
Query: 432 RDITYEYKYPEGSSEERQVMDHAFLLLSSEREHRRPVKENFLHMSVQSDDVLLGNSVNFT 491
DITY YK+PEGS ER+ ++ A S + + M V++ D ++G + +
Sbjct: 538 EDITYLYKHPEGSDAERKAVETAAAHGSKPNVYANRGSAEDVAMQVEAQDAVMGQDLMVS 597
Query: 492 VILKRKTAALQNVNILGSFELQLYTGKKMAKLCDLNKTSQI-QGQVSEVTLTLDSKTYIN 550
V+L +++ + V + + YTG + K ++ G VT+ + K Y
Sbjct: 598 VMLINHSSSRRTVKLHLYLSVTFYTGVSGTIFKETKKEVELAPGASDRVTMPVAYKEYRP 657
Query: 551 SLAILDDEPVIRGFIIAEIVESKEIMASEVFTSFQYPEFSIELPNTGRIGQLLVCNCIFK 610
L D+ + + + ES +++A + + P+ S+ L +GQ +FK
Sbjct: 658 HLV---DQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVGQECEVQIVFK 714
Query: 611 NTLAIPLTDVKFSLESLGISSLQTSDHGTVQPGETIQSQIKCTPIKTGPKKFIVKLSSKQ 670
N L + LT+V F LE G+ + + G + ET+ + P++ GP++ I L S Q
Sbjct: 715 NPLPVTLTNVVFRLEGSGLQRPKILNVGDIGGNETVTLRQSFVPVRPGPRQLIASLDSPQ 774
Query: 671 VKEIN 675
+ +++
Sbjct: 775 LSQVH 779
>gi|16445035 transglutaminase 7 [Homo sapiens]
Length = 710
Score = 420 bits (1080), Expect = e-117
Identities = 254/711 (35%), Positives = 364/711 (51%), Gaps = 35/711 (4%)
Query: 2 MDASKELQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQ-LKL 60
MD L++ +D + N HHT E RRGQ F+LRL ++P QS + +
Sbjct: 1 MDQVATLRLESVDLQSSRNNKEHHTQEMGVKRLTVRRGQPFYLRLSFSRPFQSQNDHITF 60
Query: 61 EFSTGPNPSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNV 120
TGP PS T W A+ + V++ + NA++G Y L +
Sbjct: 61 VAETGPKPSELLGTRATFFLTRVQPGNVWSASDFTIDSNSLQVSLFTPANAVIGHYTLKI 120
Query: 121 KTGN---HILKSEENILYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCK 177
+ H + LLFNPW ED V++P E +EYI+ D G Y G R I
Sbjct: 121 EISQGQGHSVTYPLGTFILLFNPWSPEDDVYLPSEILLQEYIMRDYGFVYKGHERFITSW 180
Query: 178 PWNFGQFEKNVLDCCISLLTES-------SLKPTDRRDPVLVCRAMCAMMSFEKGQGVLI 230
PWN+GQFE++++D C +L +S + + R D V VCR + AM++ GVL
Sbjct: 181 PWNYGQFEEDIIDICFEILNKSLYHLKNPAKDCSQRNDVVYVCRVVSAMINSNDDNGVLQ 240
Query: 231 GNWTGDYEGGTAPYKWTGSAPILQQYY-NTKQAVCFGQCWVFAGILTTVLRALGIPARSV 289
GNW DY G +P +W GS ILQQ+ Q V +GQCWVFA ++ TV+R LG+P R V
Sbjct: 241 GNWGEDYSKGVSPLEWKGSVAILQQWSARGGQPVKYGQCWVFASVMCTVMRCLGVPTRVV 300
Query: 290 TGFDSAHDTERNLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAV 349
+ F SAH+ +RNLT+DTY + N E +++ D +WNFHVW + WM R DLP GY+GWQ +
Sbjct: 301 SNFRSAHNVDRNLTIDTYYDRNAEMLSTQKRDKIWNFHVWNECWMIRKDLPPGYNGWQVL 360
Query: 350 DATPQERSQGVFCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHV 409
D TPQ+ S G+FCCGP+ + AIR+GD+ + YDT FV++EVN D +IWL+ QE +
Sbjct: 361 DPTPQQTSSGLFCCGPASVKAIREGDVHLAYDTPFVYAEVNADEVIWLLGDGQAQE---I 417
Query: 410 ISMETTSIGKNISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHAFLLLSSEREHRRPVK 469
++ T+SIGK ISTK VG D+R+ IT YKYPEGS EER V A + + P
Sbjct: 418 LAHNTSSIGKEISTKMVGSDQRQSITSSYKYPEGSPEERAVFMKASRKMLGPQRASLPFL 477
Query: 470 ENFLHMSVQSDDVLL----------GNSVNFTVILKR---KTAALQNVNILGSFELQ--L 514
+ ++ L G + + ++R T + ++ F Q L
Sbjct: 478 DLLESGGLRDQPAQLQLHLARIPEWGQDLQLLLRIQRVPDSTHPRGPIGLVVRFCAQALL 537
Query: 515 YTGKKMAKLCDLNKTSQIQ-GQVSEVTLTLDSKTYINSLAILDDEPVIRGFIIAEIVESK 573
+ G + G+ ++ L L Y N L DE +IR IAE+ E+
Sbjct: 538 HGGGTQKPFWRHTVRMNLDFGKETQWPLLLPYSNYRNKLT---DEKLIRVSGIAEVEETG 594
Query: 574 EIMASEVFTSFQYPEFSIELPNTGRIGQLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQ 633
M + P SIE+ +G+ L + NTL + L+ LE G+ + Q
Sbjct: 595 RSMLVLKDICLEPPHLSIEVSERAEVGKALRVHVTLTNTLMVALSSCTMVLEGSGLINGQ 654
Query: 634 -TSDHGTVQPGETIQSQIKCTPIKTGPKKFIVKLSSKQVKEINAQKIVLIT 683
D GT+ G T+Q Q+ P K GP++ V +SS +VKEI K + +T
Sbjct: 655 IAKDLGTLVAGHTLQIQLDLYPTKAGPRQLQVLISSNEVKEIKGYKDIFVT 705
>gi|148664232 transglutaminase 6 [Homo sapiens]
Length = 706
Score = 419 bits (1076), Expect = e-117
Identities = 251/705 (35%), Positives = 376/705 (53%), Gaps = 40/705 (5%)
Query: 8 LQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQLKLEFSTGPN 67
++V +D+ N +HHT E+ V RRGQ F L L L++ L L TGP
Sbjct: 4 IRVTKVDWQRSRNGAAHHTQEYPCPELVVRRGQSFSLTLELSRALDCEEILIFTMETGPR 63
Query: 68 PSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNVKTGNHIL 127
S A HT V W A + + K +TV++ S P+A++G+Y L+++ +H
Sbjct: 64 ASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSIRLSSHRK 123
Query: 128 KSEENI--LYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWNFGQFE 185
S + LLFNPWC ED VF+ E+ER+EY+L+D+G + G + I+ + WN+GQFE
Sbjct: 124 HSNRRLGEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQGWNYGQFE 183
Query: 186 KNVLDCCISLLTES----SLKPTD---RRDPVLVCRAMCAMMSFEKGQGVLIGNWTGDYE 238
+++L+ C+S+L S + TD R +P+ V R + AM++ +GV+ G W G Y
Sbjct: 184 EDILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQGQWQGKYG 243
Query: 239 GGTAPYKWTGSAPILQQYYNTK-QAVCFGQCWVFAGILTTVLRALGIPARSVTGFDSAHD 297
GGT+P W GS ILQ++ + + V +GQCWVFAG+L TVLR LGI R V+ F+SAHD
Sbjct: 244 GGTSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVSNFNSAHD 303
Query: 298 TERNLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATPQERS 357
T++NL+VD YV+ G + +T DS+WNFHVW ++W R DL Y+GWQ +DATPQE S
Sbjct: 304 TDQNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQVLDATPQEES 363
Query: 358 QGVFCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISMETTSI 417
+GVF CGP+ +TAIR+GD+ + +D FVF+EVN D + WL +E ++ T I
Sbjct: 364 EGVFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVY---SNTKKI 420
Query: 418 GKNISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHAF-LLLSSEREHRRPVKENFLHMS 476
G+ ISTKAVG D R DIT YKYPEGS +ERQV A L E RR
Sbjct: 421 GRCISTKAVGSDSRVDITDLYKYPEGSRKERQVYSKAVNRLFGVEASGRRIWIRRAGGRC 480
Query: 477 VQSDDVL-------------------LGNSVNFTVILKRKTAALQNVNILGSFELQLYTG 517
+ DD+L LG+ + + L T+ Q V + S LYT
Sbjct: 481 LWRDDLLEPATKPSIAGKFKVLEPPMLGHDLRLALCLANLTSRAQRVRVNLSGATILYTR 540
Query: 518 KKMAKLCDLNKTSQIQGQVSE-VTLTLDSKTYINSLAILDDEPVIRGFIIAEIVESKEIM 576
K +A++ + ++ Q + + +T+ Y L +D+ ++ + + + ++++
Sbjct: 541 KPVAEILHESHAVRLGPQEEKRIPITISYSKYKEDLT--EDKKILLA-AMCLVTKGEKLL 597
Query: 577 ASEVFTSFQYPEFSIELPNTGRIGQLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQTS- 635
+ T + +I++ +G + N L + D +E G+ Q S
Sbjct: 598 VEKDITLEDF--ITIKVLGPAMVGVAVTVEVTVVNPLIERVKDCALMVEGSGLLQEQLSI 655
Query: 636 DHGTVQPGETIQSQIKCTPIKTGPKKFIVKLSSKQVKEINAQKIV 680
D T++P E Q TP K+GP++ V L S +I IV
Sbjct: 656 DVPTLEPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIV 700
>gi|119395709 coagulation factor XIII A1 subunit precursor [Homo
sapiens]
Length = 732
Score = 397 bits (1021), Expect = e-110
Identities = 222/676 (32%), Positives = 366/676 (54%), Gaps = 19/676 (2%)
Query: 20 NAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQL-KLEFSTGPNPSIAKHTLVVL 78
N V HHT +++ + + RRGQ F++++ ++P L ++E+ G P K T + +
Sbjct: 61 NKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPV 120
Query: 79 DPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNVK--TGNHILKSEENI--- 133
+ W A + + V +++ SSP I+GK+++ V T +L++ N
Sbjct: 121 PIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETD 180
Query: 134 LYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWNFGQFEKNVLDCCI 193
Y+LFNPWC++D V++ +E ER+EY+LND G + G IK + W++GQFE +LD C+
Sbjct: 181 TYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCL 240
Query: 194 SLLTESSLKPTDRRDPVLVCRAMCAMMSFEKGQGVLIGNWTGDYEGGTAPYKWTGSAPIL 253
++ + + + R +P+ V R AM++ + +GVL+G+W Y G P WTGS IL
Sbjct: 241 YVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDIL 300
Query: 254 QQYYNTKQAVCFGQCWVFAGILTTVLRALGIPARSVTGFDSAHDTERNLTVDTYVNENGE 313
+Y +++ V +GQCWVFAG+ T LR LGIPAR VT + SAHD + NL +D ++ E+G
Sbjct: 301 LEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGN 360
Query: 314 KITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATPQERSQGVFCCGPSPLTAIRK 373
+ +T DSVWN+H W +AWM RPDLP G+ GWQAVD+TPQE S G++ CGP+ + AI+
Sbjct: 361 VNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKH 420
Query: 374 GDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVI-SMETTSIGKNISTKAVGQDRRR 432
G + +D FVF+EVN D LI++ +G HV+ +++ T IGK I TK +G D
Sbjct: 421 GHVCFQFDAPFVFAEVNSD-LIYITAKKDG---THVVENVDATHIGKLIVTKQIGGDGMM 476
Query: 433 DITYEYKYPEGSSEERQVMDHAFLLLSSEREHRRPV--KENFLHMSVQSDDVLLGNSVNF 490
DIT YK+ EG EER ++ A + + + + V + + M + ++ +LG
Sbjct: 477 DITDTYKFQEGQEEERLALETALMYGAKKPLNTEGVMKSRSNVDMDFEVENAVLGKDFKL 536
Query: 491 TVILKRKTAALQNVNILGSFELQLYTG--KKMAKLCDLNKTSQIQGQVSEVTLTLDSKTY 548
++ + + + S + YTG K K + T + E L + + Y
Sbjct: 537 SITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVL-IQAGEY 595
Query: 549 INSLAILDDEPVIRGFIIAEIVESKEIMASEVFTSFQYPEFSIELPNTGRIGQLLVCNCI 608
+ L ++ + F+ A I E+++++A + T PE I++ T +G +
Sbjct: 596 MGQLL---EQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVTVE 652
Query: 609 FKNTLAIPLTDVKFSLESLGISSLQTSDHGTVQPGETIQSQIKCTPIKTGPKKFIVKLSS 668
F N L L +V L+ G++ ++P T+Q + C P +G +K I +SS
Sbjct: 653 FTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSS 712
Query: 669 KQVKEINAQKIVLITK 684
++ + + V I +
Sbjct: 713 DSLRHVYGELDVQIQR 728
>gi|189458821 transglutaminase 3 precursor [Homo sapiens]
Length = 693
Score = 390 bits (1001), Expect = e-108
Identities = 236/691 (34%), Positives = 364/691 (52%), Gaps = 31/691 (4%)
Query: 8 LQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQLKLEFSTGPN 67
L V I++ N +HHT +F + + RRGQ F + +++N+ L S +L+ STGP
Sbjct: 4 LGVQSINWQTAFNRQAHHTDKFSSQELILRRGQNFQVLMIMNKGLGSNERLEFIVSTGPY 63
Query: 68 PSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQ--LNVKTGNH 125
PS + T V P + W A LQ +G +T++++S +A +G+Y L + +
Sbjct: 64 PSESAMTKAVF-PLSNGSSGGWSAVLQASNGNTLTISISSPASAPIGRYTMALQIFSQGG 122
Query: 126 ILKSEENILYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWNFGQFE 185
I + LLFNPW D VFM + ER+EY+ D G +VG+ I WNFGQFE
Sbjct: 123 ISSVKLGTFILLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWNFGQFE 182
Query: 186 KNVLDCCISLLTES-------SLKPTDRRDPVLVCRAMCAMMSFEKGQGVLIGNWTGDYE 238
+++L C+S+L S + R DP V R + AM++ GVL GNW+G Y
Sbjct: 183 EDILSICLSILDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNWSGTYT 242
Query: 239 GGTAPYKWTGSAPILQQYYNTK-QAVCFGQCWVFAGILTTVLRALGIPARSVTGFDSAHD 297
GG P W GS IL+ + + V +GQCWVFAG L T LR+LGIP+R +T F+SAHD
Sbjct: 243 GGRDPRSWNGSVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNFNSAHD 302
Query: 298 TERNLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATPQERS 357
T+RNL+VD Y + G + + DSVWNFHVW + W R DL Y GWQ +DATPQERS
Sbjct: 303 TDRNLSVDVYYDPMGNPLDKGS-DSVWNFHVWNEGWFVRSDLGPSYGGWQVLDATPQERS 361
Query: 358 QGVFCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISMETTSI 417
QGVF CGP+ + +R+GD+ + +D F+F+EVN DR+ WL G++ + ++ T I
Sbjct: 362 QGVFQCGPASVIGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNSHT--I 419
Query: 418 GKNISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHA---------FLLLSSEREHRRPV 468
G+ ISTKAVG + R D+T +YKYPEGS +ERQV A F SS
Sbjct: 420 GRYISTKAVGSNARMDVTDKYKYPEGSDQERQVFQKALGKLKPNTPFAATSSMGLETEEQ 479
Query: 469 KENFLHMSVQSDDVLLGNSVNFTVILKRKTAALQNVNILGSFELQLYTGKKMAKLCDLNK 528
+ + + + + +G VN ++LK + + V + + +Y G + ++ +
Sbjct: 480 EPSIIGKLKVAGMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAWTIIYNGTLVHEVWKDSA 539
Query: 529 TSQIQ-GQVSEVTLTLDSKTYINSLAILDDEPVIRGFIIAEIVESKEIMASEVFTSFQYP 587
T + + +E + + +Y L + +IR + ++ + E++ E P
Sbjct: 540 TMSLDPEEEAEHPIKI---SYAQYEKYLKSDNMIRITAVCKVPDESEVVV-ERDIILDNP 595
Query: 588 EFSIELPNTGRIGQLLVCNCIFKNTLAIPLTDVKFSLESLG--ISSLQTSDHGTVQPGET 645
++E+ N R+ + + +F N L P+ D +E G + +L+ D T+ P E
Sbjct: 596 TLTLEVLNEARVRKPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNLKI-DVPTLGPKEG 654
Query: 646 IQSQIKCTPIKTGPKKFIVKLSSKQVKEINA 676
+ + P ++G K+ + S + I A
Sbjct: 655 SRVRFDILPSRSGTKQLLADFSCNKFPAIKA 685
>gi|94981556 transglutaminase 5 isoform 1 [Homo sapiens]
Length = 720
Score = 386 bits (992), Expect = e-107
Identities = 239/718 (33%), Positives = 355/718 (49%), Gaps = 49/718 (6%)
Query: 8 LQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVL-NQPLQ-SYHQLKLEFSTG 65
L+V D + N V HHT E + RRGQ F+L L N+ Q + TG
Sbjct: 5 LEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTLYFRNRSFQPGLDNIIFVVETG 64
Query: 66 PNPSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNVKTGNH 125
P P +A T V W A L+ V++ + P A +G+Y L + +
Sbjct: 65 PLPDLALGTRAVFSLARHHSPSPWIAWLETNGATSTEVSLCAPPTAAVGRYLLKIHIDSF 124
Query: 126 ---ILKSEENILYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWNFG 182
+ + LLFNPWC ED V++ E +R+EY++ND G Y G+ I+ PWN+G
Sbjct: 125 QGSVTAYQLGEFILLFNPWCPEDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCPWNYG 184
Query: 183 QFEKNVLDCCISLLTESSLKPTD-------RRDPVLVCRAMCAMMSFEKGQGVLIGNWTG 235
QFE ++D C+ LL +S TD R PV V R +CAM++ GVL GNW+
Sbjct: 185 QFEDKIIDICLKLLDKSLHFQTDPATDCALRGSPVYVSRVVCAMINSNDDNGVLNGNWSE 244
Query: 236 DYEGGTAPYKWTGSAPILQQYYNTK-QAVCFGQCWVFAGILTTVLRALGIPARSVTGFDS 294
+Y G P +WTGS IL+Q+ T Q V +GQCWVFA ++ TV+R LGIP R +T FDS
Sbjct: 245 NYTDGANPAEWTGSVAILKQWNATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNFDS 304
Query: 295 AHDTERNLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATPQ 354
HDT+ NL +D Y + G + + D++WNFHVW + WM R DLP Y GWQ +DATPQ
Sbjct: 305 GHDTDGNLIIDEYYDNTGRILGNKKKDTIWNFHVWNECWMARKDLPPAYGGWQVLDATPQ 364
Query: 355 ERSQGVFCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISMET 414
E S GV+CCGP+ + AI++G++ + YDT FVFS VN D + WLV+ G+E+ + +T
Sbjct: 365 EMSNGVYCCGPASVRAIKEGEVDLNYDTPFVFSMVNADCMSWLVQ--GGKEQ--KLHQDT 420
Query: 415 TSIGKNISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHAFLLLSSEREH---------- 464
+S+G ISTK++ D R DIT YKY EGS +ERQV A L + H
Sbjct: 421 SSVGNFISTKSIQSDERDDITENYKYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQP 480
Query: 465 RRPV-----KENFLHM-SVQSDDVL-------------LGNSVNFTVILKRKTAALQNVN 505
RP LH S++ DV+ +G + F ++ ++ +++
Sbjct: 481 SRPTSLSQDSPRSLHTPSLRPSDVVQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLK 540
Query: 506 ILGSFELQLYTGKKMAKLCDLNKTSQIQGQVSEVTLTLDSKTYINSLAILDDEPVIRGFI 565
+ S + L+ G ++ T+ I E +Y L + +IR
Sbjct: 541 VNLSAQSLLHDGSPLSPF--WQDTAFITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISA 598
Query: 566 IAEIVESKEIMASEVFTSFQYPEFSIELPNTGRIGQLLVCNCIFKNTLAIPLTDVKFSLE 625
+ E S E + + YP +I + + Q L IF N L+ + D ++E
Sbjct: 599 LGEEKSSPEKILVNKIITLSYPSITINVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVE 658
Query: 626 SLGISSLQTSDH-GTVQPGETIQSQIKCTPIKTGPKKFIVKLSSKQVKEINAQKIVLI 682
G+ Q G ++P ++ P K+G ++ + S + K+I + V +
Sbjct: 659 GSGLFKKQQKVFLGVLKPQHQASIILETVPFKSGQRQIQANMRSNKFKDIKGYRNVYV 716
>gi|39777597 transglutaminase 2 isoform a [Homo sapiens]
Length = 687
Score = 360 bits (925), Expect = 2e-99
Identities = 236/709 (33%), Positives = 361/709 (50%), Gaps = 57/709 (8%)
Query: 5 SKELQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQLKLEFS- 63
++EL + D + N HHT + V RRGQ F L L L FS
Sbjct: 2 AEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSV 61
Query: 64 -TGPNPSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNVKT 122
TGP PS T R + +W AT+ ++ +++ +T+ NA +G Y+L+++
Sbjct: 62 VTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEA 121
Query: 123 GNHILKSEENI--LYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWN 180
S + LLFN WC D V++ E+ER+EY+L G Y G+A+ IK PWN
Sbjct: 122 STGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWN 181
Query: 181 FGQFEKNVLDCCISLLT-------ESSLKPTDRRDPVLVCRAMCAMMSFEKGQGVLIGNW 233
FGQFE +LD C+ LL + + R PV V R + M++ QGVL+G W
Sbjct: 182 FGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRW 241
Query: 234 TGDYEGGTAPYKWTGSAPILQQYYNTK-QAVCFGQCWVFAGILTTVLRALGIPARSVTGF 292
+Y G +P W GS IL+++ N Q V +GQCWVFA + TVLR LGIP R VT +
Sbjct: 242 DNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNY 301
Query: 293 DSAHDTERNLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDAT 352
+SAHD NL ++ + NE GE I + +WNFH W ++WM RPDL GY+GWQA+D T
Sbjct: 302 NSAHDQNSNLLIEYFRNEFGE-IQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT 360
Query: 353 PQERSQGVFCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISM 412
PQE+S+G +CCGP P+ AI++GD+ YD FVF+EVN D + W+ + +H
Sbjct: 361 PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQ---DDGSVHKSIN 417
Query: 413 ETTSIGKNISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHAFLL--LSSEREHRRPVKE 470
+ +G ISTK+VG+D R DIT+ YKYPEGSSEER+ A L L+ + E ++
Sbjct: 418 RSLIVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRI 477
Query: 471 NF-LHMSVQSDDVLLGNSVNFT-------VILKRKTAALQNV-------NILGSFELQLY 515
M++ SD + + N T ++L +T + + L + L+ +
Sbjct: 478 RVGQSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPF 537
Query: 516 TGKKMAKLCDLNKTSQIQGQVSEVTLTLDSKTYINSLAILDDEPVIRGFIIAEIVESKEI 575
+ +K LC L + + LT + + +L + EPVI +++AE +++
Sbjct: 538 S-EKSVPLCILYEKYR-------DCLTESNLIKVRALLV---EPVINSYLLAE----RDL 582
Query: 576 MASEVFTSFQYPEFSIELPNTGRIGQLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQTS 635
+ PE I + + + LV +N L + L F++E G++ Q +
Sbjct: 583 Y-------LENPEIKIRILGEPKQKRKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKT 635
Query: 636 DH--GTVQPGETIQSQIKCTPIKTGPKKFIVKLSSKQVKEINAQKIVLI 682
V+ GE ++ ++ P+ G K +V S ++K + + V+I
Sbjct: 636 VEIPDPVEAGEEVKVRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVII 684
>gi|39777599 transglutaminase 2 isoform b [Homo sapiens]
Length = 548
Score = 343 bits (879), Expect = 4e-94
Identities = 188/462 (40%), Positives = 260/462 (56%), Gaps = 16/462 (3%)
Query: 5 SKELQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQLKLEFS- 63
++EL + D + N HHT + V RRGQ F L L L FS
Sbjct: 2 AEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSV 61
Query: 64 -TGPNPSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNVKT 122
TGP PS T R + +W AT+ ++ +++ +T+ NA +G Y+L+++
Sbjct: 62 VTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEA 121
Query: 123 GNHILKSEENI--LYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWN 180
S + LLFN WC D V++ E+ER+EY+L G Y G+A+ IK PWN
Sbjct: 122 STGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWN 181
Query: 181 FGQFEKNVLDCCISLLT-------ESSLKPTDRRDPVLVCRAMCAMMSFEKGQGVLIGNW 233
FGQFE +LD C+ LL + + R PV V R + M++ QGVL+G W
Sbjct: 182 FGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRW 241
Query: 234 TGDYEGGTAPYKWTGSAPILQQYYNTK-QAVCFGQCWVFAGILTTVLRALGIPARSVTGF 292
+Y G +P W GS IL+++ N Q V +GQCWVFA + TVLR LGIP R VT +
Sbjct: 242 DNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNY 301
Query: 293 DSAHDTERNLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDAT 352
+SAHD NL ++ + NE GE I + +WNFH W ++WM RPDL GY+GWQA+D T
Sbjct: 302 NSAHDQNSNLLIEYFRNEFGE-IQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT 360
Query: 353 PQERSQGVFCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISM 412
PQE+S+G +CCGP P+ AI++GD+ YD FVF+EVN D + W+ + +H
Sbjct: 361 PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQ---DDGSVHKSIN 417
Query: 413 ETTSIGKNISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHA 454
+ +G ISTK+VG+D R DIT+ YKYPEGSSEER+ A
Sbjct: 418 RSLIVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRA 459
>gi|4759230 transglutaminase 5 isoform 2 [Homo sapiens]
Length = 638
Score = 333 bits (855), Expect = 2e-91
Identities = 200/590 (33%), Positives = 304/590 (51%), Gaps = 48/590 (8%)
Query: 131 ENILYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWNFGQFEKNVLD 190
+NI++++ ED V++ E +R+EY++ND G Y G+ I+ PWN+GQFE ++D
Sbjct: 55 DNIIFVVET----EDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCPWNYGQFEDKIID 110
Query: 191 CCISLLTESSLKPTD-------RRDPVLVCRAMCAMMSFEKGQGVLIGNWTGDYEGGTAP 243
C+ LL +S TD R PV V R +CAM++ GVL GNW+ +Y G P
Sbjct: 111 ICLKLLDKSLHFQTDPATDCALRGSPVYVSRVVCAMINSNDDNGVLNGNWSENYTDGANP 170
Query: 244 YKWTGSAPILQQYYNTK-QAVCFGQCWVFAGILTTVLRALGIPARSVTGFDSAHDTERNL 302
+WTGS IL+Q+ T Q V +GQCWVFA ++ TV+R LGIP R +T FDS HDT+ NL
Sbjct: 171 AEWTGSVAILKQWNATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNFDSGHDTDGNL 230
Query: 303 TVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATPQERSQGVFC 362
+D Y + G + + D++WNFHVW + WM R DLP Y GWQ +DATPQE S GV+C
Sbjct: 231 IIDEYYDNTGRILGNKKKDTIWNFHVWNECWMARKDLPPAYGGWQVLDATPQEMSNGVYC 290
Query: 363 CGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISMETTSIGKNIS 422
CGP+ + AI++G++ + YDT FVFS VN D + WLV+ G+E+ + +T+S+G IS
Sbjct: 291 CGPASVRAIKEGEVDLNYDTPFVFSMVNADCMSWLVQ--GGKEQ--KLHQDTSSVGNFIS 346
Query: 423 TKAVGQDRRRDITYEYKYPEGSSEERQVMDHAFLLLSSEREH----------RRPV---- 468
TK++ D R DIT YKY EGS +ERQV A L + H RP
Sbjct: 347 TKSIQSDERDDITENYKYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQPSRPTSLSQ 406
Query: 469 -KENFLHM-SVQSDDVL-------------LGNSVNFTVILKRKTAALQNVNILGSFELQ 513
LH S++ DV+ +G + F ++ ++ +++ + S +
Sbjct: 407 DSPRSLHTPSLRPSDVVQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLKVNLSAQSL 466
Query: 514 LYTGKKMAKLCDLNKTSQIQGQVSEVTLTLDSKTYINSLAILDDEPVIRGFIIAEIVESK 573
L+ G ++ T+ I E +Y L + +IR + E S
Sbjct: 467 LHDGSPLSPF--WQDTAFITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALGEEKSSP 524
Query: 574 EIMASEVFTSFQYPEFSIELPNTGRIGQLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQ 633
E + + YP +I + + Q L IF N L+ + D ++E G+ Q
Sbjct: 525 EKILVNKIITLSYPSITINVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGSGLFKKQ 584
Query: 634 TSDH-GTVQPGETIQSQIKCTPIKTGPKKFIVKLSSKQVKEINAQKIVLI 682
G ++P ++ P K+G ++ + S + K+I + V +
Sbjct: 585 QKVFLGVLKPQHQASIILETVPFKSGQRQIQANMRSNKFKDIKGYRNVYV 634
Score = 30.8 bits (68), Expect = 4.3
Identities = 16/39 (41%), Positives = 20/39 (51%)
Query: 8 LQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRL 46
L+V D + N V HHT E + RRGQ F+L L
Sbjct: 5 LEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTL 43
>gi|166362735 erythrocyte membrane protein band 4.2 isoform 1 [Homo
sapiens]
Length = 721
Score = 266 bits (679), Expect = 6e-71
Identities = 203/703 (28%), Positives = 321/703 (45%), Gaps = 42/703 (5%)
Query: 2 MDASKELQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSY----HQ 57
MDA L + DF N HHT + RRGQ F + L P++++ +
Sbjct: 32 MDA---LGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKK 88
Query: 58 LKLEFSTGPNPSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQ 117
+ L TG PS T + D W A ++ + T++VT+ +A++G Y
Sbjct: 89 VALTAQTGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYS 148
Query: 118 L--NVKTGNHILKSEENILYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIK 175
L V +L + LLFNPW +ED VF+ +E +R EY+LN G Y+G A I+
Sbjct: 149 LLLQVSGRKQLLLGQ---FTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQ 205
Query: 176 CKPWNFGQFEKNVLDCCISLLTESSLKPTDR-RDPVLVCRAMCAMMSFEKGQGVLIGNWT 234
+ W+FGQFE +V+D + LL++ K ++ PV V R + A++ F K Q VL T
Sbjct: 206 AESWDFGQFEGDVIDLSLRLLSKD--KQVEKWSQPVHVARVLGALLHFLKEQRVLPTPQT 263
Query: 235 GDYEGGTAPYKWTGSAPILQQYYNTK-QAVCFGQCWVFAGILTTVLRALGIPARSVTGFD 293
+ G K GS PIL+Q+ + + V GQ WV A + TVLR LGIPAR VT F
Sbjct: 264 QATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTTFA 323
Query: 294 SAHDTERNLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATP 353
SA T L +D Y NE G + +W F T+ WM RP LP+GYDGWQ + +
Sbjct: 324 SAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHPSA 383
Query: 354 QERSQGVFCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISME 413
+ C P+ A+++G + + +F+ +N ++W L +
Sbjct: 384 PNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAINASCVVW---KCCEDGTLELTDSN 440
Query: 414 TTSIGKNISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHAFLLLSSEREHRRPVKEN-- 471
T +G NISTK VG DR DIT YKYPEGS +E++V++ E+E K+N
Sbjct: 441 TKYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERV------EKEKMEREKDNGI 494
Query: 472 -----------FLHMSVQSDDVLLGNSVNFTVILKRKTAALQNVNILGSFELQLYTGKKM 520
+L + S L G++ +V L + + V + + Y G
Sbjct: 495 RPPSLETASPLYLLLKAPSSLPLRGDA-QISVTLVNHSEQEKAVQLAIGVQAVHYNGVLA 553
Query: 521 AKLCDLNKTSQIQGQVSEVTLTLDSKTYINSLAILDDEPVIRGFIIAEIVESKEIMASEV 580
AKL + + ++ +T+ + N + +R +A ES ++
Sbjct: 554 AKLWRKKLHLTLSANLEKI-ITI-GLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQE 611
Query: 581 FTSFQYPEFSIELPNTGRIGQLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQTS-DHGT 639
+ P +I++P Q L + +N+L P+ D S+ G+ + S +
Sbjct: 612 DIAICRPHLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRS 671
Query: 640 VQPGETIQSQIKCTPIKTGPKKFIVKLSSKQVKEINAQKIVLI 682
V P T+ ++ + TP G ++ V++ + + K V +
Sbjct: 672 VWPENTMCAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTV 714
>gi|166362737 erythrocyte membrane protein band 4.2 isoform 2 [Homo
sapiens]
Length = 691
Score = 265 bits (678), Expect = 8e-71
Identities = 200/697 (28%), Positives = 318/697 (45%), Gaps = 39/697 (5%)
Query: 8 LQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSY----HQLKLEFS 63
L + DF N HHT + RRGQ F + L P++++ ++ L
Sbjct: 5 LGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVALTAQ 64
Query: 64 TGPNPSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQL--NVK 121
TG PS T + D W A ++ + T++VT+ +A++G Y L V
Sbjct: 65 TGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLLQVS 124
Query: 122 TGNHILKSEENILYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWNF 181
+L + LLFNPW +ED VF+ +E +R EY+LN G Y+G A I+ + W+F
Sbjct: 125 GRKQLLLGQ---FTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESWDF 181
Query: 182 GQFEKNVLDCCISLLTESSLKPTDR-RDPVLVCRAMCAMMSFEKGQGVLIGNWTGDYEGG 240
GQFE +V+D + LL++ K ++ PV V R + A++ F K Q VL T + G
Sbjct: 182 GQFEGDVIDLSLRLLSKD--KQVEKWSQPVHVARVLGALLHFLKEQRVLPTPQTQATQEG 239
Query: 241 TAPYKWTGSAPILQQYYNTK-QAVCFGQCWVFAGILTTVLRALGIPARSVTGFDSAHDTE 299
K GS PIL+Q+ + + V GQ WV A + TVLR LGIPAR VT F SA T
Sbjct: 240 ALLNKRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTTFASAQGTG 299
Query: 300 RNLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATPQERSQG 359
L +D Y NE G + +W F T+ WM RP LP+GYDGWQ + +
Sbjct: 300 GRLLIDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHPSAPNGGGV 359
Query: 360 VFCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISMETTSIGK 419
+ C P+ A+++G + + +F+ +N ++W L + T +G
Sbjct: 360 LGSCDLVPVRAVKEGTLGLTPAVSDLFAAINASCVVW---KCCEDGTLELTDSNTKYVGN 416
Query: 420 NISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHAFLLLSSEREHRRPVKEN-------- 471
NISTK VG DR DIT YKYPEGS +E++V++ E+E K+N
Sbjct: 417 NISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERV------EKEKMEREKDNGIRPPSLE 470
Query: 472 -----FLHMSVQSDDVLLGNSVNFTVILKRKTAALQNVNILGSFELQLYTGKKMAKLCDL 526
+L + S L G++ +V L + + V + + Y G AKL
Sbjct: 471 TASPLYLLLKAPSSLPLRGDA-QISVTLVNHSEQEKAVQLAIGVQAVHYNGVLAAKLWRK 529
Query: 527 NKTSQIQGQVSEVTLTLDSKTYINSLAILDDEPVIRGFIIAEIVESKEIMASEVFTSFQY 586
+ + ++ +T+ + N + +R +A ES ++ +
Sbjct: 530 KLHLTLSANLEKI-ITI-GLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQEDIAICR 587
Query: 587 PEFSIELPNTGRIGQLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQTS-DHGTVQPGET 645
P +I++P Q L + +N+L P+ D S+ G+ + S +V P T
Sbjct: 588 PHLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRSVWPENT 647
Query: 646 IQSQIKCTPIKTGPKKFIVKLSSKQVKEINAQKIVLI 682
+ ++ + TP G ++ V++ + + K V +
Sbjct: 648 MCAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTV 684
>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
Length = 936
Score = 31.2 bits (69), Expect = 3.3
Identities = 24/98 (24%), Positives = 42/98 (42%), Gaps = 10/98 (10%)
Query: 43 HLRLVLNQPLQSYHQLKLEFSTGPNP---SIAKHTLVVLDPRTPSDHYNWQATLQNESGK 99
HL +++++PLQ +H NP S + L +L+ R P + + + G
Sbjct: 104 HLEVIVDRPLQVFHVEVAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGA 163
Query: 100 EVTVAVTSSPNAILGKYQLNVKTGNHILKSEENILYLL 137
+ +PN + L+VKT + E N L L+
Sbjct: 164 NAQLRYRLNPNEY---FDLDVKTN----EEETNFLELV 194
>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 816
Score = 31.2 bits (69), Expect = 3.3
Identities = 24/98 (24%), Positives = 42/98 (42%), Gaps = 10/98 (10%)
Query: 43 HLRLVLNQPLQSYHQLKLEFSTGPNP---SIAKHTLVVLDPRTPSDHYNWQATLQNESGK 99
HL +++++PLQ +H NP S + L +L+ R P + + + G
Sbjct: 104 HLEVIVDRPLQVFHVEVAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGA 163
Query: 100 EVTVAVTSSPNAILGKYQLNVKTGNHILKSEENILYLL 137
+ +PN + L+VKT + E N L L+
Sbjct: 164 NAQLRYRLNPNEY---FDLDVKTN----EEETNFLELV 194
>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
sapiens]
Length = 999
Score = 30.8 bits (68), Expect = 4.3
Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
Query: 64 TGPNPSIAKHTLVVLDPRTPS-DHYNWQATLQN-ESGKEVTVAVTSSPNAILGK 115
TG + S+ KHT + DPR + D N + N SGK V VAV + + LGK
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGK 234
>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 30.8 bits (68), Expect = 4.3
Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
Query: 64 TGPNPSIAKHTLVVLDPRTPS-DHYNWQATLQN-ESGKEVTVAVTSSPNAILGK 115
TG + S+ KHT + DPR + D N + N SGK V VAV + + LGK
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGK 234
>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
sapiens]
Length = 998
Score = 30.8 bits (68), Expect = 4.3
Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
Query: 64 TGPNPSIAKHTLVVLDPRTPS-DHYNWQATLQN-ESGKEVTVAVTSSPNAILGK 115
TG + S+ KHT + DPR + D N + N SGK V VAV + + LGK
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGK 234
>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 30.8 bits (68), Expect = 4.3
Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
Query: 64 TGPNPSIAKHTLVVLDPRTPS-DHYNWQATLQN-ESGKEVTVAVTSSPNAILGK 115
TG + S+ KHT + DPR + D N + N SGK V VAV + + LGK
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGK 234
>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
sapiens]
Length = 1043
Score = 30.8 bits (68), Expect = 4.3
Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
Query: 64 TGPNPSIAKHTLVVLDPRTPS-DHYNWQATLQN-ESGKEVTVAVTSSPNAILGK 115
TG + S+ KHT + DPR + D N + N SGK V VAV + + LGK
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGK 234
>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
sapiens]
Length = 1044
Score = 30.8 bits (68), Expect = 4.3
Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
Query: 64 TGPNPSIAKHTLVVLDPRTPS-DHYNWQATLQN-ESGKEVTVAVTSSPNAILGK 115
TG + S+ KHT + DPR + D N + N SGK V VAV + + LGK
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGK 234
>gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo
sapiens]
Length = 1052
Score = 30.8 bits (68), Expect = 4.3
Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
Query: 64 TGPNPSIAKHTLVVLDPRTPS-DHYNWQATLQN-ESGKEVTVAVTSSPNAILGK 115
TG + S+ KHT + DPR + D N + N SGK V VAV + + LGK
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGK 234
>gi|95147356 mitogen-activated protein kinase 15 [Homo sapiens]
Length = 544
Score = 30.4 bits (67), Expect = 5.7
Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 6/62 (9%)
Query: 317 SMTHDSVWNFHVWTDAWMKRPDL-PKGYDGWQAVDATPQERS---QGVFCCGPSPLTAIR 372
++ H V FH +D W + D+ P+ ++G Q + P+ RS Q + CG S T+
Sbjct: 298 ALQHPYVQRFHCPSDEWAREADVRPRAHEGVQL--SVPEYRSRVYQMILECGGSSGTSRE 355
Query: 373 KG 374
KG
Sbjct: 356 KG 357
>gi|66932941 XC chemokine receptor 1 [Homo sapiens]
Length = 333
Score = 30.4 bits (67), Expect = 5.7
Identities = 13/27 (48%), Positives = 16/27 (59%)
Query: 256 YYNTKQAVCFGQCWVFAGILTTVLRAL 282
YY+ + C Q WVFA + TTVL L
Sbjct: 14 YYDLQSQPCENQAWVFATLATTVLYCL 40
>gi|4885339 XC chemokine receptor 1 [Homo sapiens]
Length = 333
Score = 30.4 bits (67), Expect = 5.7
Identities = 13/27 (48%), Positives = 16/27 (59%)
Query: 256 YYNTKQAVCFGQCWVFAGILTTVLRAL 282
YY+ + C Q WVFA + TTVL L
Sbjct: 14 YYDLQSQPCENQAWVFATLATTVLYCL 40
>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
Length = 976
Score = 30.0 bits (66), Expect = 7.4
Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 8/72 (11%)
Query: 210 VLVCRAMCAMMSFEKGQGVLIGNWTGDYE--GGTAPYKWTGSAPILQQYYNTKQAVCFGQ 267
+LV + +C +S + G L+ ++ G YE GG P +WT I + + T V
Sbjct: 755 ILVNQNLCCKVS-DFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDV---- 809
Query: 268 CWVFAGILTTVL 279
W F ++ VL
Sbjct: 810 -WSFGIVMWEVL 820
>gi|145977194 hypothetical protein LOC400793 isoform 2 [Homo
sapiens]
Length = 272
Score = 30.0 bits (66), Expect = 7.4
Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 4/56 (7%)
Query: 46 LVLNQPLQSYHQLKLEFSTGPNPSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEV 101
L+ +QP+ S LE+ T P+P A+ + P P+D +AT++ E +V
Sbjct: 138 LISSQPVLS----SLEYGTEPSPGQAQDSAPTAQPDVPADASQPEATMEREERGKV 189
>gi|207028635 hypothetical protein LOC400793 isoform 1 [Homo
sapiens]
Length = 315
Score = 30.0 bits (66), Expect = 7.4
Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 4/56 (7%)
Query: 46 LVLNQPLQSYHQLKLEFSTGPNPSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEV 101
L+ +QP+ S LE+ T P+P A+ + P P+D +AT++ E +V
Sbjct: 181 LISSQPVLS----SLEYGTEPSPGQAQDSAPTAQPDVPADASQPEATMEREERGKV 232
>gi|51173724 bystin [Homo sapiens]
Length = 437
Score = 30.0 bits (66), Expect = 7.4
Identities = 14/41 (34%), Positives = 19/41 (46%)
Query: 45 RLVLNQPLQSYHQLKLEFSTGPNPSIAKHTLVVLDPRTPSD 85
R +L Q Q +L+ E TG P+ + L PR P D
Sbjct: 56 RRILQQARQQQEELEAEHGTGDKPAAPRERTTRLGPRMPQD 96
>gi|8922108 cytokine-like 1 [Homo sapiens]
Length = 136
Score = 30.0 bits (66), Expect = 7.4
Identities = 12/32 (37%), Positives = 19/32 (59%)
Query: 127 LKSEENILYLLFNPWCKEDMVFMPDEDERKEY 158
LK + LY + N +C+ D+VF+ D+ EY
Sbjct: 92 LKDKARKLYTIMNSFCRRDLVFLLDDCNALEY 123
>gi|19923084 polycystin-1L1 [Homo sapiens]
Length = 2849
Score = 30.0 bits (66), Expect = 7.4
Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 2/70 (2%)
Query: 592 ELPNTGRIGQLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQTSDHGTVQPGE--TIQSQ 649
E+PN L + N KN + +P V L SLG+ ++ S + P E T
Sbjct: 923 EIPNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGLGAISESSQLNLLPTEPGTADPD 982
Query: 650 IKCTPIKTGP 659
TP P
Sbjct: 983 ATTTPFSREP 992
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,178,727
Number of Sequences: 37866
Number of extensions: 1118442
Number of successful extensions: 2400
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 2322
Number of HSP's gapped (non-prelim): 34
length of query: 684
length of database: 18,247,518
effective HSP length: 109
effective length of query: 575
effective length of database: 14,120,124
effective search space: 8119071300
effective search space used: 8119071300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.