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Search of human proteins with 156616292
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156616292 EF-hand domain (C-terminal) containing 1 [Homo
sapiens]
(640 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156616292 EF-hand domain (C-terminal) containing 1 [Homo sapi... 1304 0.0
gi|31542743 EF-hand domain (C-terminal) containing 2 [Homo sapiens] 359 4e-99
gi|4885111 calmodulin-like 3 [Homo sapiens] 52 2e-06
gi|58218968 calmodulin 3 [Homo sapiens] 51 3e-06
gi|4502549 calmodulin 2 [Homo sapiens] 51 3e-06
gi|5901912 calmodulin 1 [Homo sapiens] 51 3e-06
gi|148613876 EF hand domain family, member B [Homo sapiens] 49 1e-05
gi|29568111 myosin regulatory light chain 9 isoform a [Homo sapi... 39 0.019
gi|5453740 myosin, light chain 12A, regulatory, non-sarcomeric [... 37 0.043
gi|146229340 mutated in colorectal cancers isoform 1 [Homo sapiens] 37 0.056
gi|4507617 fast skeletal muscle troponin C [Homo sapiens] 37 0.056
gi|169167243 PREDICTED: similar to myosin regulatory light chain... 37 0.073
gi|222144326 myosin regulatory light chain MRCL2 isoform A [Homo... 36 0.095
gi|222144328 myosin regulatory light chain MRCL2 isoform B [Homo... 36 0.095
gi|222144324 myosin regulatory light chain MRCL2 isoform A [Homo... 36 0.095
gi|15809016 myosin regulatory light chain MRCL2 isoform A [Homo ... 36 0.095
gi|22212896 protein phosphatase 3 regulatory subunit B, beta iso... 35 0.21
gi|4507615 troponin C, slow [Homo sapiens] 35 0.21
gi|32698884 calcium binding protein 7 [Homo sapiens] 35 0.28
gi|88981341 PREDICTED: similar to myosin regulatory light chain ... 35 0.28
gi|51464364 PREDICTED: similar to myosin regulatory light chain ... 35 0.28
gi|21264326 rhomboid protease 3 [Homo sapiens] 34 0.36
gi|50897266 calmodulin-like 6 [Homo sapiens] 34 0.36
gi|63054822 calneuron 1 isoform 2 [Homo sapiens] 34 0.47
gi|157743275 calneuron 1 isoform 1 [Homo sapiens] 34 0.47
gi|4757902 caltractin [Homo sapiens] 32 1.4
gi|4757974 centrin 1 [Homo sapiens] 32 1.4
gi|4557777 slow skeletal ventricular myosin alkali light chain 3... 32 1.8
gi|4506025 protein phosphatase 3, regulatory subunit B, alpha is... 32 2.3
gi|23312386 serine/threonine protein phosphatase with EF-hand mo... 32 2.3
>gi|156616292 EF-hand domain (C-terminal) containing 1 [Homo
sapiens]
Length = 640
Score = 1304 bits (3375), Expect = 0.0
Identities = 640/640 (100%), Positives = 640/640 (100%)
Query: 1 MVSNPVHGLPFLPGTSFKDSTKTAFHRSQTLSYRNGYAIVRRPTVGIGGDRLQFNQLSQA 60
MVSNPVHGLPFLPGTSFKDSTKTAFHRSQTLSYRNGYAIVRRPTVGIGGDRLQFNQLSQA
Sbjct: 1 MVSNPVHGLPFLPGTSFKDSTKTAFHRSQTLSYRNGYAIVRRPTVGIGGDRLQFNQLSQA 60
Query: 61 ELDELASKAPVLTYGQPKQAPPADFIPAHVAFDKKVLKFDAYFQEDVPMSTEEQYRIRQV 120
ELDELASKAPVLTYGQPKQAPPADFIPAHVAFDKKVLKFDAYFQEDVPMSTEEQYRIRQV
Sbjct: 61 ELDELASKAPVLTYGQPKQAPPADFIPAHVAFDKKVLKFDAYFQEDVPMSTEEQYRIRQV 120
Query: 121 NIYYYLEDDSMSVIEPVVENSGILQGKLIKRQRLAKNDRGDHYHWKDLNRGINITIYGKT 180
NIYYYLEDDSMSVIEPVVENSGILQGKLIKRQRLAKNDRGDHYHWKDLNRGINITIYGKT
Sbjct: 121 NIYYYLEDDSMSVIEPVVENSGILQGKLIKRQRLAKNDRGDHYHWKDLNRGINITIYGKT 180
Query: 181 FRVVDCDQFTQVFLESQGIELNPPEKMALDPYTELRKQPLRKYVTPSDFDQLKQFLTFDK 240
FRVVDCDQFTQVFLESQGIELNPPEKMALDPYTELRKQPLRKYVTPSDFDQLKQFLTFDK
Sbjct: 181 FRVVDCDQFTQVFLESQGIELNPPEKMALDPYTELRKQPLRKYVTPSDFDQLKQFLTFDK 240
Query: 241 QVLRFYAIWDDTDSMYGECRTYIIHYYLMDDTVEIREVHERNDGRDPFPLLMNRQRVPKV 300
QVLRFYAIWDDTDSMYGECRTYIIHYYLMDDTVEIREVHERNDGRDPFPLLMNRQRVPKV
Sbjct: 241 QVLRFYAIWDDTDSMYGECRTYIIHYYLMDDTVEIREVHERNDGRDPFPLLMNRQRVPKV 300
Query: 301 LVENAKNFPQCVLEISDQEVLEWYTAKDFIVGKSLTILGRTFFIYDCDPFTRRYYKEKFG 360
LVENAKNFPQCVLEISDQEVLEWYTAKDFIVGKSLTILGRTFFIYDCDPFTRRYYKEKFG
Sbjct: 301 LVENAKNFPQCVLEISDQEVLEWYTAKDFIVGKSLTILGRTFFIYDCDPFTRRYYKEKFG 360
Query: 361 ITDLPRIDVSKREPPPVKQELPPYNGFGLVEDSAQNCFALIPKAPKKDVIKMLVNDNKVL 420
ITDLPRIDVSKREPPPVKQELPPYNGFGLVEDSAQNCFALIPKAPKKDVIKMLVNDNKVL
Sbjct: 361 ITDLPRIDVSKREPPPVKQELPPYNGFGLVEDSAQNCFALIPKAPKKDVIKMLVNDNKVL 420
Query: 421 RYLAVLESPIPEDKDRRFVFSYFLATDMISIFEPPVRNSGIIGGKYLGRTKVVKPYSTVD 480
RYLAVLESPIPEDKDRRFVFSYFLATDMISIFEPPVRNSGIIGGKYLGRTKVVKPYSTVD
Sbjct: 421 RYLAVLESPIPEDKDRRFVFSYFLATDMISIFEPPVRNSGIIGGKYLGRTKVVKPYSTVD 480
Query: 481 NPVYYGPSDFFIGAVIEVFGHRFIILDTDEYVLKYMESNAAQYSPEALASIQNHVRKREA 540
NPVYYGPSDFFIGAVIEVFGHRFIILDTDEYVLKYMESNAAQYSPEALASIQNHVRKREA
Sbjct: 481 NPVYYGPSDFFIGAVIEVFGHRFIILDTDEYVLKYMESNAAQYSPEALASIQNHVRKREA 540
Query: 541 PAPEAESKQTEKDPGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFF 600
PAPEAESKQTEKDPGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFF
Sbjct: 541 PAPEAESKQTEKDPGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFF 600
Query: 601 KICESLNVPVDDSLVKELIRMCSHGEGKINYYNFVRAFSN 640
KICESLNVPVDDSLVKELIRMCSHGEGKINYYNFVRAFSN
Sbjct: 601 KICESLNVPVDDSLVKELIRMCSHGEGKINYYNFVRAFSN 640
>gi|31542743 EF-hand domain (C-terminal) containing 2 [Homo sapiens]
Length = 749
Score = 359 bits (922), Expect = 4e-99
Identities = 238/721 (33%), Positives = 357/721 (49%), Gaps = 114/721 (15%)
Query: 9 LPFLPGTSFKDST-KTAFHRSQTLSYRNGYA-IVRRPTVGIGGDRLQFNQLSQAELDELA 66
LP LPG SF + K FH+SQ + N +V GIGG+ L L Q ++
Sbjct: 3 LPLLPGNSFNRNVGKEKFHKSQHWGFCNNVMMLVSDEKPGIGGEPL----LGQ----KIK 54
Query: 67 SKAPVLTYGQPKQAPPADFIPAHVAFDKKVLKFDAYFQEDVPMSTEEQYRIRQVNIYYYL 126
K + G +P+ VAFDK+VL FDAY +E+V ++ YRIR IY+Y
Sbjct: 55 PKCSIYPKGDGSD------VPSWVAFDKQVLSFDAYLEEEVLDKSQTNYRIRYYKIYFYP 108
Query: 127 EDDSMSVIEPVVENSGILQGKLIKRQR--LAKNDRGDHYHWKDLNRGINITIYGKTFRVV 184
EDD++ V EP V+NSG+LQG I+R R L D Y N G + YG+TF++
Sbjct: 109 EDDTIQVNEPEVKNSGLLQGTSIRRHRITLPPPDEDQFYTVYHFNVGTEVVFYGRTFKIY 168
Query: 185 DCDQFTQVFLESQGIELNPPEKMALDPYTELRK------QPLRKYVTPSDFDQLKQFLTF 238
DCD FT+ FL G+++NPP + DPY ++R+ +PLR Y D LKQFL +
Sbjct: 169 DCDAFTRNFLRKIGVKVNPPVQCPEDPYMKIRREVVEHVEPLRPY---ESLDTLKQFLQY 225
Query: 239 DKQVLRFYAIWDDTDSMYGECRTYIIHYYLMDDTVEIREVHERNDGRDPFPLLMNRQRVP 298
++L F+ +WDD+ SM+G+ R I+HY+L DDT+EI+E+ + GRD + + R ++P
Sbjct: 226 HGKILCFFCLWDDSVSMFGDRRELILHYFLCDDTIEIKELLPHSSGRDALKMFLRRSKLP 285
Query: 299 KVLVENAKNFPQCVL---EISDQEVL--------------------------EWYTAKDF 329
KN P V +I+D+ VL E+Y D
Sbjct: 286 -------KNCPPRVYQPGQITDRAVLNSYGDFIKNQADGYLFDRYKLGKVDQEFYKDSDL 338
Query: 330 IVGKSLTILGRTFFIYDCDPFTRRYYKEKFGITDLPRIDVSKREPPP-VKQELPPYNGFG 388
+G ++ + GR +YDCD FT+ YYK K+GI + + PPP ++++ PPYNGFG
Sbjct: 339 SLGVTINVWGRKVLLYDCDEFTKSYYKSKYGIENFTSVSCKPPSPPPKIERKFPPYNGFG 398
Query: 389 LVEDSAQNCFALIPKAPKKDVIKMLVND-----NKVLRYLAVLESPIPEDKDRRFVFSYF 443
EDS +NC L P +++ K + D + +LR+ A L + D DR FV SY+
Sbjct: 399 SEEDSLRNCIDLKPTPHRRNFKKFMEKDSYGSKSNILRFFAKLVTDKCVDLDRMFVISYY 458
Query: 444 LATDMISIFEPPVRNSGIIGGKYLGRTKVVKPYSTV---DNPVYYGPSDFFIGAVIEVFG 500
L D IS+FEP RNSGI GG +L R++V KP V + Y + +IG + V G
Sbjct: 459 LGDDTISVFEPIERNSGIAGGMFLKRSRVKKPGQEVFKSELSEYIKAEELYIGVTVNVNG 518
Query: 501 HRFIILDTDEYVLKYMESNAAQYSPEALASIQNHVRKREAPAPE-------AESKQTE-- 551
+ F +L+ DEY L YME N +Y L +++ E + E A+SK T
Sbjct: 519 YLFRLLNADEYTLNYMEQNTDKYPFSNLKLALQKLKQEEGKSRELKQVFKAADSKHTNMV 578
Query: 552 -----KD-------PGVQELEALIDTIQKQLKDHSCKD--------------NIREAFQI 585
+D + E E + ++ + +C D N+ E F
Sbjct: 579 DYNTFRDILMSLTVGNLAEQEFVTIARHYRVPEGTCSDMDFLIALAHEKFKKNMFENFDT 638
Query: 586 Y-------DKEASGYVDRDMFFKICESLNVPVDDSLVKELIRMCSHGEGKINYYNFVRAF 638
+ D+E + ++C+S +P+ D L++ L+ E +I+Y +F A
Sbjct: 639 FIYSCVYEDREKKNVLPTKDIKRLCKSSRLPLSDDLLESLLSRFEDSEKQIDYKSFFSAL 698
Query: 639 S 639
+
Sbjct: 699 N 699
>gi|4885111 calmodulin-like 3 [Homo sapiens]
Length = 149
Score = 52.0 bits (123), Expect = 2e-06
Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Query: 539 EAPAPEAESKQTEKDPGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDM 598
EA + S+ G + + + +++KD ++ IREAF+++DK+ +G+V
Sbjct: 46 EAELRDMMSEIDRDGNGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAE 105
Query: 599 FFKICESLNVPVDDSLVKELIRMC-SHGEGKINYYNFVR 636
+ L + D V E+IR + G+G++NY FVR
Sbjct: 106 LRHVMTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEFVR 144
>gi|58218968 calmodulin 3 [Homo sapiens]
Length = 149
Score = 51.2 bits (121), Expect = 3e-06
Identities = 24/83 (28%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
Query: 555 GVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDDSL 614
G + + + +++KD ++ IREAF+++DK+ +GY+ + +L + D
Sbjct: 62 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEE 121
Query: 615 VKELIRMCS-HGEGKINYYNFVR 636
V E+IR G+G++NY FV+
Sbjct: 122 VDEMIREADIDGDGQVNYEEFVQ 144
>gi|4502549 calmodulin 2 [Homo sapiens]
Length = 149
Score = 51.2 bits (121), Expect = 3e-06
Identities = 24/83 (28%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
Query: 555 GVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDDSL 614
G + + + +++KD ++ IREAF+++DK+ +GY+ + +L + D
Sbjct: 62 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEE 121
Query: 615 VKELIRMCS-HGEGKINYYNFVR 636
V E+IR G+G++NY FV+
Sbjct: 122 VDEMIREADIDGDGQVNYEEFVQ 144
>gi|5901912 calmodulin 1 [Homo sapiens]
Length = 149
Score = 51.2 bits (121), Expect = 3e-06
Identities = 24/83 (28%), Positives = 46/83 (55%), Gaps = 1/83 (1%)
Query: 555 GVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDDSL 614
G + + + +++KD ++ IREAF+++DK+ +GY+ + +L + D
Sbjct: 62 GTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEE 121
Query: 615 VKELIRMCS-HGEGKINYYNFVR 636
V E+IR G+G++NY FV+
Sbjct: 122 VDEMIREADIDGDGQVNYEEFVQ 144
>gi|148613876 EF hand domain family, member B [Homo sapiens]
Length = 833
Score = 49.3 bits (116), Expect = 1e-05
Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Query: 555 GVQELEALIDTIQKQLK--DHSCKDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDD 612
G ALI ++ LK ++ D + AF+ YDK+ G +D+D + C+ N+ +DD
Sbjct: 540 GKDRQRALIAAVRHHLKKVNYQKFDTLLAAFRHYDKKGDGMIDKDELQEACDQANLSLDD 599
Query: 613 SLVKELIRMCS-HGEGKINYYNF 634
L+ +L C +G INY F
Sbjct: 600 KLLDQLFDYCDVDNDGFINYLEF 622
>gi|29568111 myosin regulatory light chain 9 isoform a [Homo
sapiens]
Length = 172
Score = 38.5 bits (88), Expect = 0.019
Identities = 25/97 (25%), Positives = 40/97 (41%), Gaps = 1/97 (1%)
Query: 541 PAPEAESKQTEKDPGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFF 600
P E + PG + ++L +D IR AF +D+EASG++ D
Sbjct: 65 PTDEYLEGMMSEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLR 124
Query: 601 KICESLNVPVDDSLVKELIRMCS-HGEGKINYYNFVR 636
++ ++ D V E+ R +G NY F R
Sbjct: 125 ELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTR 161
Score = 32.0 bits (71), Expect = 1.8
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 15/97 (15%)
Query: 545 AESKQTEKDP--GVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFKI 602
A++K T+K P + A+ D Q Q +EAF + D+ G++D++ +
Sbjct: 6 AKAKTTKKRPQRATSNVFAMFDQSQIQ--------EFKEAFNMIDQNRDGFIDKEDLHDM 57
Query: 603 CESLNV-PVDDSLVKELIRMCSHGEGKINYYNFVRAF 638
SL P D+ L M S G IN+ F+ F
Sbjct: 58 LASLGKNPTDEYLE----GMMSEAPGPINFTMFLTMF 90
>gi|5453740 myosin, light chain 12A, regulatory, non-sarcomeric
[Homo sapiens]
Length = 171
Score = 37.4 bits (85), Expect = 0.043
Identities = 25/97 (25%), Positives = 39/97 (40%), Gaps = 1/97 (1%)
Query: 541 PAPEAESKQTEKDPGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFF 600
P E + PG + ++L +D IR AF +D+EA+G + D
Sbjct: 64 PTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLR 123
Query: 601 KICESLNVPVDDSLVKELIRMCS-HGEGKINYYNFVR 636
++ ++ D V EL R +G NY F R
Sbjct: 124 ELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTR 160
>gi|146229340 mutated in colorectal cancers isoform 1 [Homo sapiens]
Length = 1019
Score = 37.0 bits (84), Expect = 0.056
Identities = 16/61 (26%), Positives = 35/61 (57%), Gaps = 2/61 (3%)
Query: 576 KDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDDSLVKELIRMCSHGEGKINYYNFV 635
++ +R FQ D + GY+ R+ +C LN +++S+ + + ++ + GKI++ +F
Sbjct: 37 EERMRRLFQTCDGDGDGYISRNDLLMVCRQLN--MEESVAEIMNQLGADENGKISFQDFT 94
Query: 636 R 636
R
Sbjct: 95 R 95
>gi|4507617 fast skeletal muscle troponin C [Homo sapiens]
Length = 160
Score = 37.0 bits (84), Expect = 0.056
Identities = 20/90 (22%), Positives = 48/90 (53%), Gaps = 4/90 (4%)
Query: 551 EKDPGVQELEALIDTIQKQLKDHS---CKDNIREAFQIYDKEASGYVDRDMFFKICESLN 607
E G + E + + +Q+K+ + ++ + E F+I+D+ A GY+D + +I +
Sbjct: 65 EDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAECFRIFDRNADGYIDPEELAEIFRASG 124
Query: 608 VPVDDSLVKELIR-MCSHGEGKINYYNFVR 636
V D ++ L++ + +G+I++ F++
Sbjct: 125 EHVTDEEIESLMKDGDKNNDGRIDFDEFLK 154
>gi|169167243 PREDICTED: similar to myosin regulatory light chain
MRCL2 [Homo sapiens]
Length = 377
Score = 36.6 bits (83), Expect = 0.073
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 554 PGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDDS 613
PG L+ K+L +D IR AF +D+EA+G + D ++ ++ D
Sbjct: 283 PGPINFTMLLAMFGKKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTVGDQFTDE 342
Query: 614 LVKELIRMCS-HGEGKINYYNF 634
V EL S +G NY F
Sbjct: 343 EVDELYTEASIDKKGNFNYIEF 364
>gi|222144326 myosin regulatory light chain MRCL2 isoform A [Homo
sapiens]
Length = 172
Score = 36.2 bits (82), Expect = 0.095
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 1/84 (1%)
Query: 554 PGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDDS 613
PG + ++L +D IR AF +D+EA+G + D ++ ++ D
Sbjct: 78 PGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDE 137
Query: 614 LVKELIRMCS-HGEGKINYYNFVR 636
V EL R +G NY F R
Sbjct: 138 EVDELYREAPIDKKGNFNYIEFTR 161
Score = 31.6 bits (70), Expect = 2.3
Identities = 25/97 (25%), Positives = 43/97 (44%), Gaps = 13/97 (13%)
Query: 544 EAESKQTEKDP--GVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFK 601
+A++K T+K P + A+ D Q Q +EAF + D+ G++D++
Sbjct: 5 KAKTKTTKKRPQRATSNVFAMFDQSQIQ--------EFKEAFNMIDQNRDGFIDKEDLHD 56
Query: 602 ICESLNVPVDDSLVKELIRMCSHGEGKINYYNFVRAF 638
+ SL D+ L M + G IN+ F+ F
Sbjct: 57 MLASLGKNPTDAY---LDAMMNEAPGPINFTMFLTMF 90
>gi|222144328 myosin regulatory light chain MRCL2 isoform B [Homo
sapiens]
Length = 154
Score = 36.2 bits (82), Expect = 0.095
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 1/84 (1%)
Query: 554 PGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDDS 613
PG + ++L +D IR AF +D+EA+G + D ++ ++ D
Sbjct: 60 PGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDE 119
Query: 614 LVKELIRMCS-HGEGKINYYNFVR 636
V EL R +G NY F R
Sbjct: 120 EVDELYREAPIDKKGNFNYIEFTR 143
Score = 29.6 bits (65), Expect = 8.9
Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 3/67 (4%)
Query: 572 DHSCKDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDDSLVKELIRMCSHGEGKINY 631
D S +EAF + D+ G++D++ + SL D+ L M + G IN+
Sbjct: 9 DQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAY---LDAMMNEAPGPINF 65
Query: 632 YNFVRAF 638
F+ F
Sbjct: 66 TMFLTMF 72
>gi|222144324 myosin regulatory light chain MRCL2 isoform A [Homo
sapiens]
Length = 172
Score = 36.2 bits (82), Expect = 0.095
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 1/84 (1%)
Query: 554 PGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDDS 613
PG + ++L +D IR AF +D+EA+G + D ++ ++ D
Sbjct: 78 PGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDE 137
Query: 614 LVKELIRMCS-HGEGKINYYNFVR 636
V EL R +G NY F R
Sbjct: 138 EVDELYREAPIDKKGNFNYIEFTR 161
Score = 31.6 bits (70), Expect = 2.3
Identities = 25/97 (25%), Positives = 43/97 (44%), Gaps = 13/97 (13%)
Query: 544 EAESKQTEKDP--GVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFK 601
+A++K T+K P + A+ D Q Q +EAF + D+ G++D++
Sbjct: 5 KAKTKTTKKRPQRATSNVFAMFDQSQIQ--------EFKEAFNMIDQNRDGFIDKEDLHD 56
Query: 602 ICESLNVPVDDSLVKELIRMCSHGEGKINYYNFVRAF 638
+ SL D+ L M + G IN+ F+ F
Sbjct: 57 MLASLGKNPTDAY---LDAMMNEAPGPINFTMFLTMF 90
>gi|15809016 myosin regulatory light chain MRCL2 isoform A [Homo
sapiens]
Length = 172
Score = 36.2 bits (82), Expect = 0.095
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 1/84 (1%)
Query: 554 PGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDDS 613
PG + ++L +D IR AF +D+EA+G + D ++ ++ D
Sbjct: 78 PGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDE 137
Query: 614 LVKELIRMCS-HGEGKINYYNFVR 636
V EL R +G NY F R
Sbjct: 138 EVDELYREAPIDKKGNFNYIEFTR 161
Score = 31.6 bits (70), Expect = 2.3
Identities = 25/97 (25%), Positives = 43/97 (44%), Gaps = 13/97 (13%)
Query: 544 EAESKQTEKDP--GVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFK 601
+A++K T+K P + A+ D Q Q +EAF + D+ G++D++
Sbjct: 5 KAKTKTTKKRPQRATSNVFAMFDQSQIQ--------EFKEAFNMIDQNRDGFIDKEDLHD 56
Query: 602 ICESLNVPVDDSLVKELIRMCSHGEGKINYYNFVRAF 638
+ SL D+ L M + G IN+ F+ F
Sbjct: 57 MLASLGKNPTDAY---LDAMMNEAPGPINFTMFLTMF 90
>gi|22212896 protein phosphatase 3 regulatory subunit B, beta
isoform [Homo sapiens]
Length = 173
Score = 35.0 bits (79), Expect = 0.21
Identities = 40/167 (23%), Positives = 69/167 (41%), Gaps = 21/167 (12%)
Query: 477 STVDNPVYYGPSDF---FIGAVIEVFGHRFIILDTDEYVLKYMESNAAQYSPEALASIQN 533
ST+ N Y P++ F I+ G RF LD D+ + S E S+
Sbjct: 2 STMGNEASY-PAEMCSHFDNDEIKRLGRRFKKLDLDK---------SGSLSVEEFMSLPE 51
Query: 534 HVRKREAPAPEAESKQTEKDPGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGY 593
+R + T+ D V E ++ T Q +K + +R AF IYD + GY
Sbjct: 52 -LRHNPLVRRVIDVFDTDGDGEVDFKEFILGTSQFSVKGDE-EQKLRFAFSIYDMDKDGY 109
Query: 594 VDRDMFFKICESL------NVPVDDSLVKELIRMCSHGEGKINYYNF 634
+ F++ + + + + + K +I + G+GKI++ F
Sbjct: 110 ISNGELFQVLKMMVGNNLTDWQLQQLVDKTIIILDKDGDGKISFEEF 156
>gi|4507615 troponin C, slow [Homo sapiens]
Length = 161
Score = 35.0 bits (79), Expect = 0.21
Identities = 19/89 (21%), Positives = 47/89 (52%), Gaps = 4/89 (4%)
Query: 551 EKDPGVQELEALIDTIQKQLKDHS---CKDNIREAFQIYDKEASGYVDRDMFFKICESLN 607
E G + + + + + +KD S ++ + + F+++DK A GY+D D + ++
Sbjct: 66 EDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKIMLQATG 125
Query: 608 VPVDDSLVKELIR-MCSHGEGKINYYNFV 635
+ + ++EL++ + +G+I+Y F+
Sbjct: 126 ETITEDDIEELMKDGDKNNDGRIDYDEFL 154
>gi|32698884 calcium binding protein 7 [Homo sapiens]
Length = 215
Score = 34.7 bits (78), Expect = 0.28
Identities = 16/60 (26%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 577 DNIREAFQIYDKEASGYVDRDMFFKICESLN-VPVDDSLVKELIRMCSHGEGKINYYNFV 635
+ IREAF+++D++ +G++ + SL +P + L + R+ G+G++++ FV
Sbjct: 36 EEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGDGQVDFEEFV 95
>gi|88981341 PREDICTED: similar to myosin regulatory light chain
MRCL2 [Homo sapiens]
Length = 377
Score = 34.7 bits (78), Expect = 0.28
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 1/82 (1%)
Query: 554 PGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDDS 613
PG L+ K+L +D IR AF +D+EA+G + D ++ ++ D
Sbjct: 283 PGPINFTMLLAMFGKKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTVGDQFTDE 342
Query: 614 LVKELIRMCS-HGEGKINYYNF 634
V EL +G NY F
Sbjct: 343 EVDELYTEAPIDKKGNFNYIEF 364
>gi|51464364 PREDICTED: similar to myosin regulatory light chain
MRCL2 [Homo sapiens]
Length = 377
Score = 34.7 bits (78), Expect = 0.28
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 1/82 (1%)
Query: 554 PGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDDS 613
PG L+ K+L +D IR AF +D+EA+G + D ++ ++ D
Sbjct: 283 PGPINFTMLLAMFGKKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTVGDQFTDE 342
Query: 614 LVKELIRMCS-HGEGKINYYNF 634
V EL +G NY F
Sbjct: 343 EVDELYTEAPIDKKGNFNYIEF 364
>gi|21264326 rhomboid protease 3 [Homo sapiens]
Length = 404
Score = 34.3 bits (77), Expect = 0.36
Identities = 19/66 (28%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
Query: 576 KDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDDSLVKELIRMC-SHGEGKINYYNF 634
+D+ + F +D +GY+ F + ES + +D + L+ + SH +G+I Y +F
Sbjct: 36 EDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDF 95
Query: 635 VRAFSN 640
V SN
Sbjct: 96 VSLMSN 101
>gi|50897266 calmodulin-like 6 [Homo sapiens]
Length = 181
Score = 34.3 bits (77), Expect = 0.36
Identities = 16/66 (24%), Positives = 36/66 (54%), Gaps = 1/66 (1%)
Query: 571 KDHSCKDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDDSLVKELIRMC-SHGEGKI 629
K + + +R AF+++DKE GY+D + + + P+++ +++++ G+ I
Sbjct: 104 KAQNQESELRAAFRVFDKEGKGYIDWNTLKYVLMNAGEPLNEVEAEQMMKEADKDGDRTI 163
Query: 630 NYYNFV 635
+Y FV
Sbjct: 164 DYEEFV 169
>gi|63054822 calneuron 1 isoform 2 [Homo sapiens]
Length = 219
Score = 33.9 bits (76), Expect = 0.47
Identities = 16/60 (26%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Query: 577 DNIREAFQIYDKEASGYVDRDMFFKICESLN-VPVDDSLVKELIRMCSHGEGKINYYNFV 635
D IREAF++ D++ +G++ + SL +P + L + R+ G+G++++ F+
Sbjct: 39 DEIREAFRVLDRDGNGFISKQELGMAMRSLGYMPSEVELAIIMQRLDMDGDGQVDFDEFM 98
>gi|157743275 calneuron 1 isoform 1 [Homo sapiens]
Length = 261
Score = 33.9 bits (76), Expect = 0.47
Identities = 16/60 (26%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Query: 577 DNIREAFQIYDKEASGYVDRDMFFKICESLN-VPVDDSLVKELIRMCSHGEGKINYYNFV 635
D IREAF++ D++ +G++ + SL +P + L + R+ G+G++++ F+
Sbjct: 81 DEIREAFRVLDRDGNGFISKQELGMAMRSLGYMPSEVELAIIMQRLDMDGDGQVDFDEFM 140
>gi|4757902 caltractin [Homo sapiens]
Length = 172
Score = 32.3 bits (72), Expect = 1.4
Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Query: 576 KDNIREAFQIYDKEASGYVDRDMFFKICESLNV-PVDDSLVKELIRMCSHGEGKINYYNF 634
K IREAF ++D + +G +D +L P + + K + + G GK+N+ +F
Sbjct: 30 KQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDF 89
Query: 635 V 635
+
Sbjct: 90 L 90
Score = 32.0 bits (71), Expect = 1.8
Identities = 16/91 (17%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
Query: 547 SKQTEKDPGVQELEALIDTIQKQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFKICESL 606
S+ ++ G + + +++ + K+ I +AF+++D + +G + ++ + L
Sbjct: 74 SEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKEL 133
Query: 607 NVPVDDSLVKELIRMCSH-GEGKINYYNFVR 636
+ D ++E+I G+G+++ F+R
Sbjct: 134 GENLTDEELQEMIDEADRDGDGEVSEQEFLR 164
>gi|4757974 centrin 1 [Homo sapiens]
Length = 172
Score = 32.3 bits (72), Expect = 1.4
Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Query: 576 KDNIREAFQIYDKEASGYVDRDMFFKICESLNV-PVDDSLVKELIRMCSHGEGKINYYNF 634
K +REAF ++D + SG +D +L P + + K + + G GKI++ +F
Sbjct: 30 KQEVREAFDLFDVDGSGTIDAKELKVAMRALGFEPRKEEMKKMISEVDREGTGKISFNDF 89
Query: 635 V 635
+
Sbjct: 90 L 90
Score = 32.3 bits (72), Expect = 1.4
Identities = 15/70 (21%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
Query: 568 KQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDDSLVKELIRMCSH-GE 626
+++ + K+ I +AF+++D + +G + ++ L + D ++E+I G+
Sbjct: 95 QKMSEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGENLTDEELQEMIDEADRDGD 154
Query: 627 GKINYYNFVR 636
G++N F+R
Sbjct: 155 GEVNEEEFLR 164
>gi|4557777 slow skeletal ventricular myosin alkali light chain 3
[Homo sapiens]
Length = 195
Score = 32.0 bits (71), Expect = 1.8
Identities = 30/144 (20%), Positives = 61/144 (42%), Gaps = 7/144 (4%)
Query: 496 IEVFGHRFIILD-TDEYVLKYMESNAAQYSPEALASIQNHVRKREAPAPEAESKQTEKDP 554
IE F F++ D T + +K + L ++ + + E + +Q E +
Sbjct: 51 IEEFKEAFMLFDRTPKCEMKITYGQCG----DVLRALGQNPTQAEVLRVLGKPRQEELNT 106
Query: 555 GVQELEALIDTIQ--KQLKDHSCKDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDD 612
+ + E + +Q + KD ++ E +++DKE +G V + +L + +
Sbjct: 107 KMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTE 166
Query: 613 SLVKELIRMCSHGEGKINYYNFVR 636
V++L+ G INY FV+
Sbjct: 167 DEVEKLMAGQEDSNGCINYEAFVK 190
>gi|4506025 protein phosphatase 3, regulatory subunit B, alpha
isoform 1 [Homo sapiens]
Length = 170
Score = 31.6 bits (70), Expect = 2.3
Identities = 15/65 (23%), Positives = 32/65 (49%), Gaps = 6/65 (9%)
Query: 576 KDNIREAFQIYDKEASGYVDRDMFFKICESL------NVPVDDSLVKELIRMCSHGEGKI 629
+ +R AF+IYD + GY+ F++ + + + + + K +I G+G+I
Sbjct: 89 EQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRI 148
Query: 630 NYYNF 634
++ F
Sbjct: 149 SFEEF 153
>gi|23312386 serine/threonine protein phosphatase with EF-hand
motifs 2 [Homo sapiens]
Length = 753
Score = 31.6 bits (70), Expect = 2.3
Identities = 19/68 (27%), Positives = 36/68 (52%), Gaps = 5/68 (7%)
Query: 576 KDNIREAFQIYDKEASGYVDRDMF---FKICES-LNVPVDDSLVKELIRMCS-HGEGKIN 630
+ N+ F+I D + SG++ D F +K+ S +N+ + D + +L R + +G I+
Sbjct: 654 RSNLETIFRIIDSDHSGFISLDEFRQTWKLFSSHMNIDITDDCICDLARSIDFNKDGHID 713
Query: 631 YYNFVRAF 638
F+ AF
Sbjct: 714 INEFLEAF 721
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.139 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,069,047
Number of Sequences: 37866
Number of extensions: 1156255
Number of successful extensions: 3249
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 3162
Number of HSP's gapped (non-prelim): 84
length of query: 640
length of database: 18,247,518
effective HSP length: 109
effective length of query: 531
effective length of database: 14,120,124
effective search space: 7497785844
effective search space used: 7497785844
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.