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Search of human proteins with 156523244
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo
sapiens]
(402 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo sa... 850 0.0
gi|57977325 membrane-associated ring finger (C3HC4) 4 [Homo sapi... 326 3e-89
gi|40255016 membrane-associated RING-CH protein IX [Homo sapiens] 305 6e-83
gi|8923613 membrane-associated RING-CH protein I [Homo sapiens] 75 8e-14
gi|50539414 cellular modulator of immune recognition isoform 7 [... 73 4e-13
gi|50539412 cellular modulator of immune recognition isoform 6 [... 73 4e-13
gi|50539410 cellular modulator of immune recognition isoform 8 [... 73 4e-13
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 69 6e-12
gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 66 5e-11
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 66 6e-11
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 64 2e-10
gi|33356148 formin-like 1 [Homo sapiens] 63 5e-10
gi|32307177 forkhead box G1 [Homo sapiens] 62 7e-10
gi|30425370 membrane-associated ring finger (C3HC4) 3 [Homo sapi... 61 2e-09
gi|33286436 gametogenetin [Homo sapiens] 60 5e-09
gi|157168329 formin 1 [Homo sapiens] 58 2e-08
gi|169167066 PREDICTED: hypothetical protein [Homo sapiens] 58 2e-08
gi|113416187 PREDICTED: hypothetical protein [Homo sapiens] 58 2e-08
gi|113415691 PREDICTED: hypothetical protein [Homo sapiens] 58 2e-08
gi|52485606 formin-like 2 [Homo sapiens] 58 2e-08
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 57 3e-08
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 57 4e-08
gi|22027541 programmed cell death 7 [Homo sapiens] 57 4e-08
gi|11386183 WAS protein family, member 2 [Homo sapiens] 56 7e-08
gi|153792074 proline rich 12 [Homo sapiens] 56 7e-08
gi|210032580 SET domain containing 1B [Homo sapiens] 55 1e-07
gi|53729334 membrane-associated ring finger (C3HC4) 2 isoform 2 ... 55 1e-07
gi|53729332 membrane-associated ring finger (C3HC4) 2 isoform 1 ... 55 1e-07
gi|53729330 membrane-associated ring finger (C3HC4) 2 isoform 1 ... 55 1e-07
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 54 2e-07
>gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo
sapiens]
Length = 402
Score = 850 bits (2195), Expect = 0.0
Identities = 402/402 (100%), Positives = 402/402 (100%)
Query: 1 MSFEGGHGGSRCRGAESGDAEPPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPE 60
MSFEGGHGGSRCRGAESGDAEPPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPE
Sbjct: 1 MSFEGGHGGSRCRGAESGDAEPPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPE 60
Query: 61 RAAGPSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGPG 120
RAAGPSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGPG
Sbjct: 61 RAAGPSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGPG 120
Query: 121 ESEAGAGGERERRGAGDQPETRSVCSSRSSSSGGGDQRAGHQHQHHQPICKICFQGAEQG 180
ESEAGAGGERERRGAGDQPETRSVCSSRSSSSGGGDQRAGHQHQHHQPICKICFQGAEQG
Sbjct: 121 ESEAGAGGERERRGAGDQPETRSVCSSRSSSSGGGDQRAGHQHQHHQPICKICFQGAEQG 180
Query: 181 ELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELCCYRYHVIAIKMKQPCQWQSISITLV 240
ELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELCCYRYHVIAIKMKQPCQWQSISITLV
Sbjct: 181 ELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELCCYRYHVIAIKMKQPCQWQSISITLV 240
Query: 241 EKVQMIAVILGSLFLIASVTWLLWSAFSPYAVWQRKDILFQICYGMYGFMDLVCIGLIVH 300
EKVQMIAVILGSLFLIASVTWLLWSAFSPYAVWQRKDILFQICYGMYGFMDLVCIGLIVH
Sbjct: 241 EKVQMIAVILGSLFLIASVTWLLWSAFSPYAVWQRKDILFQICYGMYGFMDLVCIGLIVH 300
Query: 301 EGAAVYRVFKRWRAVNLHWDVLNYDKATDIEESSRGESSTSRTLWLPLTALRNRNLVHPT 360
EGAAVYRVFKRWRAVNLHWDVLNYDKATDIEESSRGESSTSRTLWLPLTALRNRNLVHPT
Sbjct: 301 EGAAVYRVFKRWRAVNLHWDVLNYDKATDIEESSRGESSTSRTLWLPLTALRNRNLVHPT 360
Query: 361 QLTSPRFQCGYVLLHLFNRMRPHEDLSEDNSSGEVVMRVTSV 402
QLTSPRFQCGYVLLHLFNRMRPHEDLSEDNSSGEVVMRVTSV
Sbjct: 361 QLTSPRFQCGYVLLHLFNRMRPHEDLSEDNSSGEVVMRVTSV 402
>gi|57977325 membrane-associated ring finger (C3HC4) 4 [Homo
sapiens]
Length = 410
Score = 326 bits (835), Expect = 3e-89
Identities = 183/391 (46%), Positives = 227/391 (58%), Gaps = 53/391 (13%)
Query: 28 PPPPPTPPPGEPAPVP-AAPRYLPPLPASPETPERAAGPSEPLGEVAPRCRGADELPPPP 86
PP P P G+P P AA LP L A R GP E +G P +PPPP
Sbjct: 57 PPQAPLPMHGDPQPPGLAANNTLPALGAGGWAGWR--GPREVVGREPP------PVPPPP 108
Query: 87 LPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGPGESEAGAGGERERRGAGDQPETRSVCS 146
PL P+ E G + E P L +A++ E +T S
Sbjct: 109 -PLPPSSVEDDWGGPATEPPASLLSSASSDDFCKE------------------KTEDRYS 149
Query: 147 SRSSSSGGGDQRAGHQHQHHQPICKICFQGAEQGELLNPCRCDGSVRYTHQLCLLKWISE 206
SS G P+C+ICFQG EQGELL+PCRCDGSV+ THQ CL+KWISE
Sbjct: 150 LGSSLDSG----------MRTPLCRICFQGPEQGELLSPCRCDGSVKCTHQPCLIKWISE 199
Query: 207 RGSWTCELCCYRYHVIAIKMKQPCQWQSISITLVEKVQMIAVILGSLFLIASVTWLLWSA 266
RG W+CELC Y+YHVIAI K P QWQ+IS+T++EKVQ+ A ILGSLFLIAS++WL+WS
Sbjct: 200 RGCWSCELCYYKYHVIAISTKNPLQWQAISLTVIEKVQVAAAILGSLFLIASISWLIWST 259
Query: 267 FSPYAVWQRKDILFQICYGMYGFMDLVCIGLIVHEGAAVYRVFKRWRAVNLHWDVLNYDK 326
FSP A WQR+D+LFQICYGMYGFMD+VCIGLI+HEG +VYR+FKRW+AVN W VLNYDK
Sbjct: 260 FSPSARWQRQDLLFQICYGMYGFMDVVCIGLIIHEGPSVYRIFKRWQAVNQQWKVLNYDK 319
Query: 327 ATDIEESSRG-----ESSTSRTLWLPLTALRNRNLVHPTQLTS----------PRFQCGY 371
D+E+ G +S+S +P + P Q + C Y
Sbjct: 320 TKDLEDQKAGGRTNPRTSSSTQANIPSSEEETAGTPAPEQGPAQAAGHPSGPLSHHHCAY 379
Query: 372 VLLHLFNRMRPHEDLSEDNSSGEVVMRVTSV 402
+LH+ + +RPHE S SS E+VMRVT+V
Sbjct: 380 TILHILSHLRPHEQRSPPGSSRELVMRVTTV 410
Score = 30.4 bits (67), Expect = 3.0
Identities = 21/46 (45%), Positives = 23/46 (50%), Gaps = 5/46 (10%)
Query: 5 GGHGGSRCRGA-ESGDAEPPPQPPPPP-PPTPPP---GEPAPVPAA 45
G G + RG E EPPP PPPPP PP+ G PA P A
Sbjct: 83 GAGGWAGWRGPREVVGREPPPVPPPPPLPPSSVEDDWGGPATEPPA 128
>gi|40255016 membrane-associated RING-CH protein IX [Homo sapiens]
Length = 346
Score = 305 bits (780), Expect = 6e-83
Identities = 157/327 (48%), Positives = 203/327 (62%), Gaps = 28/327 (8%)
Query: 103 GEGPRRLPEAAAAKGGPGESEAGAGGERERRGAGDQPETRSVCSSRSSSSGGGDQRAGHQ 162
G PR P+ +GG G A G R G GD+ E +G + RAG
Sbjct: 21 GGRPRAEPQPRGGRGG-GCGWAPFAGCSTRDGDGDEEEYYGSEPRARGLAGDKEPRAGPL 79
Query: 163 HQHHQPI-----------------------CKICFQGAEQGELLNPCRCDGSVRYTHQLC 199
P+ C+ICFQG EQGELL+PCRCDGSVR THQ C
Sbjct: 80 PPPAPPLPPPGALDALSLSSSLDSGLRTPQCRICFQGPEQGELLSPCRCDGSVRCTHQPC 139
Query: 200 LLKWISERGSWTCELCCYRYHVIAIKMKQPCQWQSISITLVEKVQMIAVILGSLFLIASV 259
L++WISERGSW+CELC ++Y V+AI K P QWQ+IS+T++EKVQ+ A++LGSLFL+AS+
Sbjct: 140 LIRWISERGSWSCELCYFKYQVLAISTKNPLQWQAISLTVIEKVQIAAIVLGSLFLVASI 199
Query: 260 TWLLWSAFSPYAVWQRKDILFQICYGMYGFMDLVCIGLIVHEGAAVYRVFKRWRAVNLHW 319
+WL+WS+ SP A WQR+D+LFQICYGMYGFMD+VCIGLI+HEG++VYR+FKRW+AVN W
Sbjct: 200 SWLIWSSLSPSAKWQRQDLLFQICYGMYGFMDVVCIGLIIHEGSSVYRIFKRWQAVNQQW 259
Query: 320 DVLNYDKATDI----EESSRGESSTSRTLWLPLTALRNRNLVHPTQLTSPRFQCGYVLLH 375
VLNYDK DI + G+S + P + +R T +CGY +LH
Sbjct: 260 KVLNYDKTKDIGGDAGGGTAGKSGPRNSRTGPTSGATSRPPAAQRMRTLLPQRCGYTILH 319
Query: 376 LFNRMRPHEDLSEDNSSGEVVMRVTSV 402
L ++RP + S +S EVVMRVT+V
Sbjct: 320 LLGQLRPPDARSSSHSGREVVMRVTTV 346
Score = 34.3 bits (77), Expect = 0.20
Identities = 17/28 (60%), Positives = 18/28 (64%), Gaps = 2/28 (7%)
Query: 11 RCRGAESGDAEPPPQP-PPPPPPTPPPG 37
R RG +GD EP P PPP PP PPPG
Sbjct: 64 RARGL-AGDKEPRAGPLPPPAPPLPPPG 90
>gi|8923613 membrane-associated RING-CH protein I [Homo sapiens]
Length = 272
Score = 75.5 bits (184), Expect = 8e-14
Identities = 34/99 (34%), Positives = 57/99 (57%), Gaps = 2/99 (2%)
Query: 167 QPICKICF-QGAEQGELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELCCYRYHVIAIK 225
Q IC+IC +G E+ L+ PCRC G++R+ HQ CL +WI + CELC Y + ++ K
Sbjct: 60 QDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDF-IMETK 118
Query: 226 MKQPCQWQSISITLVEKVQMIAVILGSLFLIASVTWLLW 264
+K +W+ + +T E+ ++ + + I V W L+
Sbjct: 119 LKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLY 157
>gi|50539414 cellular modulator of immune recognition isoform 7
[Homo sapiens]
Length = 291
Score = 73.2 bits (178), Expect = 4e-13
Identities = 32/99 (32%), Positives = 56/99 (56%), Gaps = 2/99 (2%)
Query: 167 QPICKICF-QGAEQGELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELCCYRYHVIAIK 225
Q IC+IC +G ++ L+ PC C GS+ + HQ CL +WI + CELC Y + ++ K
Sbjct: 77 QDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEF-IMETK 135
Query: 226 MKQPCQWQSISITLVEKVQMIAVILGSLFLIASVTWLLW 264
+K +W+ + +T E+ +++ + + I V W L+
Sbjct: 136 LKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLY 174
>gi|50539412 cellular modulator of immune recognition isoform 6
[Homo sapiens]
Length = 291
Score = 73.2 bits (178), Expect = 4e-13
Identities = 32/99 (32%), Positives = 56/99 (56%), Gaps = 2/99 (2%)
Query: 167 QPICKICF-QGAEQGELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELCCYRYHVIAIK 225
Q IC+IC +G ++ L+ PC C GS+ + HQ CL +WI + CELC Y + ++ K
Sbjct: 77 QDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEF-IMETK 135
Query: 226 MKQPCQWQSISITLVEKVQMIAVILGSLFLIASVTWLLW 264
+K +W+ + +T E+ +++ + + I V W L+
Sbjct: 136 LKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLY 174
>gi|50539410 cellular modulator of immune recognition isoform 8
[Homo sapiens]
Length = 291
Score = 73.2 bits (178), Expect = 4e-13
Identities = 32/99 (32%), Positives = 56/99 (56%), Gaps = 2/99 (2%)
Query: 167 QPICKICF-QGAEQGELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELCCYRYHVIAIK 225
Q IC+IC +G ++ L+ PC C GS+ + HQ CL +WI + CELC Y + ++ K
Sbjct: 77 QDICRICHCEGDDESPLITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEF-IMETK 135
Query: 226 MKQPCQWQSISITLVEKVQMIAVILGSLFLIASVTWLLW 264
+K +W+ + +T E+ +++ + + I V W L+
Sbjct: 136 LKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLY 174
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 69.3 bits (168), Expect = 6e-12
Identities = 51/153 (33%), Positives = 58/153 (37%), Gaps = 45/153 (29%)
Query: 23 PPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPRCRGADEL 82
PP P P PTPPP + P AP PP P TP +A GP
Sbjct: 142 PPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGP----------------- 184
Query: 83 PPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGG--PGESEAGAGGERERRGAGDQPE 140
PPPP AA G GP++ P KGG PG + G G G +P
Sbjct: 185 PPPP----------AAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPP 234
Query: 141 TRSVCSSRSSSSGGGDQRAGHQH------QHHQ 167
R GGG+ R G QH QHHQ
Sbjct: 235 HR----------GGGEPRGGRQHHPPYHQQHHQ 257
Score = 33.5 bits (75), Expect = 0.35
Identities = 35/133 (26%), Positives = 46/133 (34%), Gaps = 25/133 (18%)
Query: 5 GGHGGSRCRGAESGDAEPPPQPPPPP---------PPTPPPGEPAPVPAAPRYLPPLPAS 55
GG GG RG G PPP P P PG+ P P P P
Sbjct: 11 GGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIP------PPP 64
Query: 56 PETPERAAGPSEPLGEVAPRCRGADELPPPPLPLQ----PAGQEVAAAGDSGEGPRRLPE 111
P ++ P +P + P + PP P P Q P + ++ +GP P
Sbjct: 65 PHQQQQQPPPQQPPPQQPP----PHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPG 120
Query: 112 AAAAKGGPGESEA 124
+A P S A
Sbjct: 121 VGSAP--PASSSA 131
>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
potassium channel 2 [Homo sapiens]
Length = 889
Score = 66.2 bits (160), Expect = 5e-11
Identities = 51/140 (36%), Positives = 56/140 (40%), Gaps = 7/140 (5%)
Query: 1 MSFEGGHGGSRCRGAESGDAEPPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPE 60
M GG G R ES A P P PPPPPPP PP +P P P P PA P+ P
Sbjct: 1 MDARGGGG----RPGESPGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPP 56
Query: 61 RA-AGPSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGP 119
RA A P E E PR R P P A +GE R P+ + A GP
Sbjct: 57 RAEALPPEAADEGGPRGRLRSRDSSCGRPGTPGAASTAKGSPNGECGRGEPQCSPA--GP 114
Query: 120 GESEAGAGGERERRGAGDQP 139
G RGA P
Sbjct: 115 EGPARGPKVSFSCRGAASGP 134
Score = 47.0 bits (110), Expect = 3e-05
Identities = 43/132 (32%), Positives = 50/132 (37%), Gaps = 10/132 (7%)
Query: 18 GDAEPPPQPPPPPPPTPPPGEPAPVPAAPRYLP--PLPASPETPERAAGPSEPLGEVAPR 75
G A P PPPP + PPG PA P APR P LPA+P AGP+ P ++
Sbjct: 764 GPAPAAASPGPPPPAS-PPGAPAS-PRAPRTSPYGGLPAAP-----LAGPALPARRLSRA 816
Query: 76 CRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGPGESEAGAGGERERRGA 135
R P LP G + S PR P AA P + G
Sbjct: 817 SRPL-SASQPSLPHGAPGPAASTRPASSSTPRLGPTPAARAAAPSPDRRDSASPGAAGGL 875
Query: 136 GDQPETRSVCSS 147
Q RS SS
Sbjct: 876 DPQDSARSRLSS 887
Score = 41.2 bits (95), Expect = 0.002
Identities = 51/172 (29%), Positives = 56/172 (32%), Gaps = 59/172 (34%)
Query: 26 PPPPPPP--------------------------------------TPPPGEPAPVPAAPR 47
PPPPPPP PPPG PAP A+P
Sbjct: 715 PPPPPPPQVTSAIATLQQAAAMSFCPQVARPLVGPLALGSPRLVRRPPPG-PAPAAASPG 773
Query: 48 YLPPLPASPETPERAAGPSEPLGEVAPRCRGADELPPPPL--PLQPAGQEVAAAGDSGEG 105
PP PASP P P APR LP PL P PA + A+
Sbjct: 774 --PPPPASP--------PGAPASPRAPRTSPYGGLPAAPLAGPALPARRLSRASRPLSAS 823
Query: 106 PRRLPEAAAAKGGPGESEAGAGGERERRGAGDQPETRSVCSS---RSSSSGG 154
LP A GP S A R G P R+ S R S+S G
Sbjct: 824 QPSLPHGAP---GPAASTRPASSSTPR--LGPTPAARAAAPSPDRRDSASPG 870
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 65.9 bits (159), Expect = 6e-11
Identities = 57/164 (34%), Positives = 71/164 (43%), Gaps = 28/164 (17%)
Query: 20 AEPPPQPPPPPPPT---------PPPGEP--APVPAAPRYLPPLPASPETPERAAGPSEP 68
AEPPP+PPPPPPPT PPP P P+ AP + P LP E GP P
Sbjct: 1343 AEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAP-HCPRLPLRKTYRENVGGPGAP 1401
Query: 69 LGEVAPRCRGADELPPPPLPLQ----PAG--QEVAAAGDS-----GEGPRRLPEAAAAKG 117
G A R RG P PLP + +G +E+AA D +GP P A+AA+G
Sbjct: 1402 EGTPAGRARGGS---PAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQG 1458
Query: 118 GPGESEAGAGGERERRGAGDQPETRSVCSSRSSSSGGGDQRAGH 161
G +R + P+ +S SS S D H
Sbjct: 1459 TGDPDWEAPGLPPAKRRKSESPDVDQ--ASFSSDSPQDDTLTEH 1500
Score = 44.7 bits (104), Expect = 2e-04
Identities = 37/121 (30%), Positives = 41/121 (33%), Gaps = 29/121 (23%)
Query: 15 AESGDAEPPPQPPPPPPPTPPPG--------------EPAPVPAAPRYLP---------- 50
A GD+ P P P PP+ PP P P P AP LP
Sbjct: 783 APLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLG 842
Query: 51 -PLPASPETPERAAGPSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRL 109
P PAS P P PL + G P PP P P +A S E RL
Sbjct: 843 VPPPASNPAPTAPGPPQPPLRPQSQPPEG----PLPPAPHLPPSSTSSAVASSSETSSRL 898
Query: 110 P 110
P
Sbjct: 899 P 899
Score = 35.8 bits (81), Expect = 0.070
Identities = 34/128 (26%), Positives = 44/128 (34%), Gaps = 28/128 (21%)
Query: 22 PPPQPPPPPPP-------TPPPGEPAPVPAAPRY--LPP----------LPASPETPERA 62
P P PPPPPP TP P P P R+ +P PA+P+T
Sbjct: 930 PEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSL 989
Query: 63 AGPSEPLGEVAPRCRGADELP------PPPLPLQPAGQEVAAAGDSGEGPRRLPE---AA 113
+ P V + P P P P+ G ++ LP A
Sbjct: 990 GPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAK 1049
Query: 114 AAKGGPGE 121
AA GPG+
Sbjct: 1050 AASSGPGK 1057
Score = 35.0 bits (79), Expect = 0.12
Identities = 27/84 (32%), Positives = 30/84 (35%), Gaps = 25/84 (29%)
Query: 22 PPPQPPP---------------PPPPTPPPGEPAP--VPAAPRYLP---PLPASPETPER 61
PPPQ PP PP P P P P P P+ P PLP +P P
Sbjct: 823 PPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLP-- 880
Query: 62 AAGPSEPLGEVAPRCRGADELPPP 85
PS VA + LP P
Sbjct: 881 ---PSSTSSAVASSSETSSRLPAP 901
Score = 33.9 bits (76), Expect = 0.27
Identities = 47/186 (25%), Positives = 62/186 (33%), Gaps = 31/186 (16%)
Query: 24 PQPPP-----PPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAP-RCR 77
P PPP P P PPP P P LP ER P G + +
Sbjct: 920 PTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERF--HQVPSGIILQNKAG 977
Query: 78 GADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGPGESEAGAGG-----ERER 132
GA P L P A+ SG+ P P A P + A G E
Sbjct: 978 GAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTP--TAPSHAPAPAPMAATGLPPLLPAEN 1035
Query: 133 RGAGDQPETRSVCSSRSSSSGGGDQRAGHQHQHH----------QPICKICF---QGAEQ 179
+ T +V + SS G + +G Q++ QP + CF Q
Sbjct: 1036 KAFASNLPTLNVAKAASSGPG---KPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQ 1092
Query: 180 GELLNP 185
G +L+P
Sbjct: 1093 GSVLHP 1098
Score = 32.7 bits (73), Expect = 0.60
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 8/84 (9%)
Query: 13 RGAESGDAEPPPQPPPPPPPTPPPGEP--APVPAAPRYLP---PLPASPETPERAAGPSE 67
+GA G P Q P P P P P P P++ LP PL SP P + P+
Sbjct: 741 KGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLP--SPHPTR 798
Query: 68 PLGEVAPRCRGADELPPPPLPLQP 91
P R + PP PL P
Sbjct: 799 PPSRPPSRPQSVSR-PPSEPPLHP 821
Score = 32.7 bits (73), Expect = 0.60
Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 15/76 (19%)
Query: 24 PQPPPPPPPTPP------PGEPAPVPAAPRYLPP------LPASPETPERAAGPSEPLGE 71
P P P PP PP P E P+P AP +LPP + +S ET R P+ +
Sbjct: 850 PAPTAPGPPQPPLRPQSQPPE-GPLPPAP-HLPPSSTSSAVASSSETSSRLPAPTPSDFQ 907
Query: 72 VA-PRCRGADELPPPP 86
+ P +G + P PP
Sbjct: 908 LQFPPSQGPHKSPTPP 923
Score = 32.0 bits (71), Expect = 1.0
Identities = 39/145 (26%), Positives = 48/145 (33%), Gaps = 40/145 (27%)
Query: 14 GAESGDAEPPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPS------- 66
G + A+ PPQ P P PP P+ P L +SPE PS
Sbjct: 638 GLQQPQAQQPPQAPTPQAAAPPQA------TTPQPSPGLASSPEKIVLGQPPSATPTAIL 691
Query: 67 --EPLGEVAPRCRGADEL-----------------PPP---PLPLQPAGQEVA---AAGD 101
+ L P+ R L PPP P P P + A D
Sbjct: 692 TQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPD 751
Query: 102 SGEGPRRLPE--AAAAKGGPGESEA 124
S P P+ AAA GPG S +
Sbjct: 752 SQASPAPAPQIPAAAPLKGPGPSSS 776
Score = 31.2 bits (69), Expect = 1.7
Identities = 28/99 (28%), Positives = 36/99 (36%), Gaps = 19/99 (19%)
Query: 31 PPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPRCRGADELPPP----- 85
P P G+P V P +PA R P +P + A LPP
Sbjct: 316 PTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQP--------KPAGVLPPKLYQLT 367
Query: 86 PLPLQPAGQEVAAAGDSG------EGPRRLPEAAAAKGG 118
P P PAG + G+ G + P+ L AA K G
Sbjct: 368 PKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAG 406
Score = 29.6 bits (65), Expect = 5.0
Identities = 20/70 (28%), Positives = 24/70 (34%), Gaps = 7/70 (10%)
Query: 29 PPPPTPPPGEPAPV-------PAAPRYLPPLPASPETPERAAGPSEPLGEVAPRCRGADE 81
P P GE APV A P PLP + P+ P P + A +
Sbjct: 605 PATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP 664
Query: 82 LPPPPLPLQP 91
P P L P
Sbjct: 665 QPSPGLASSP 674
Score = 29.6 bits (65), Expect = 5.0
Identities = 33/131 (25%), Positives = 45/131 (34%), Gaps = 15/131 (11%)
Query: 21 EPPPQPPP-----------PPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPL 69
+P PQ PP P PP P P AAP P +P A+ P + +
Sbjct: 622 QPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAP---PQATTPQPSPGLASSPEKIV 678
Query: 70 GEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGPGESEAGAGGE 129
P L L + QE + S EGP A+ P ++ A
Sbjct: 679 LGQPPSATPTAILTQDSLQMF-LPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPAT 737
Query: 130 RERRGAGDQPE 140
+GAG P+
Sbjct: 738 PVAKGAGLGPQ 748
Score = 29.6 bits (65), Expect = 5.0
Identities = 20/72 (27%), Positives = 28/72 (38%), Gaps = 7/72 (9%)
Query: 20 AEPPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPRCRGA 79
++PP P PP P PP + V ++ LPA + + P +P
Sbjct: 866 SQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSP----- 920
Query: 80 DELPPPPLPLQP 91
PPP L L P
Sbjct: 921 --TPPPTLHLVP 930
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 63.9 bits (154), Expect = 2e-10
Identities = 41/103 (39%), Positives = 46/103 (44%), Gaps = 8/103 (7%)
Query: 22 PPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETP---ERAAGPSEPLGEVAPRCRG 78
P P PP PPP T PP P P P PPLP+ P P E+ P + R RG
Sbjct: 411 PSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRG 470
Query: 79 ADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGPGE 121
PP P Q A +E A AG G P P + A GGP E
Sbjct: 471 R----PPLTPSQRAEREAARAGPEGTSP-PTPTPSTATGGPPE 508
Score = 48.1 bits (113), Expect = 1e-05
Identities = 37/110 (33%), Positives = 44/110 (40%), Gaps = 10/110 (9%)
Query: 22 PPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPRCRGADE 81
PPP PPPPP P+PP P PA P L +P+ A + P GA E
Sbjct: 621 PPPAPPPPPAPSPP-----PAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPE 675
Query: 82 LP---PPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGPGESEAGAGG 128
P PPP PA E A G + LP A P ++E G
Sbjct: 676 APEPEPPPADDSPAEPEPRAVGRTNH--LSLPRFAPVVTTPVKAEVSPHG 723
Score = 43.5 bits (101), Expect = 3e-04
Identities = 37/99 (37%), Positives = 42/99 (42%), Gaps = 16/99 (16%)
Query: 21 EPPPQPP---------PPPPPTPP-PGEPAPVPAAPRY-LPPLPASPETPERAAGPSEPL 69
E PP+PP PP +PP P EPAPVP+ PR PP P +R + EP
Sbjct: 549 EDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPT 608
Query: 70 GEVAPRCRGADELPPPP--LPLQPAGQEVAAAGDSGEGP 106
R ELPPPP P PA A S P
Sbjct: 609 FRWTSLTR---ELPPPPPAPPPPPAPSPPPAPATSSRRP 644
Score = 39.3 bits (90), Expect = 0.006
Identities = 31/110 (28%), Positives = 41/110 (37%), Gaps = 18/110 (16%)
Query: 15 AESGDAEPPPQPPPPPPPTPPPGEPA-------------PVPAAPRYLPPLPASPETPER 61
A G+ PPP PP PPT P P PV R PP P P T
Sbjct: 2205 AGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVL 2264
Query: 62 AAGPSEPLGEVAPRCR-----GADELPPPPLPLQPAGQEVAAAGDSGEGP 106
++GP+ P + R G PPP ++ A+ D+ + P
Sbjct: 2265 SSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVP 2314
Score = 38.5 bits (88), Expect = 0.011
Identities = 47/151 (31%), Positives = 58/151 (38%), Gaps = 22/151 (14%)
Query: 14 GAESGDAEPPPQPPPPPPPTPPPGEPAPVPAAPR------YLPPLPASPETPERAAGPSE 67
G+ S P P P PP P P APR PPL SP+ R P+
Sbjct: 1889 GSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQL--RVPPPTS 1946
Query: 68 PL-------GEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKG-GP 119
+ GE+AP G PPPP L P +++ SG L AA+ G P
Sbjct: 1947 VVTALTPTSGELAP--PGPAPSPPPPEDLGPDFEDMEVV--SGLSAADLDFAASLLGTEP 2002
Query: 120 GESEAGAGGE--RERRGAGDQPETRSVCSSR 148
+ E A G G GD E S +SR
Sbjct: 2003 FQEEIVAAGAMGSSHGGPGDSSEEESSPTSR 2033
Score = 32.0 bits (71), Expect = 1.0
Identities = 34/137 (24%), Positives = 53/137 (38%), Gaps = 11/137 (8%)
Query: 20 AEPPPQPPPPPPPTP---PPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPRC 76
A PPPQP PPP+P PP E A + + LP S + + ++
Sbjct: 752 ALPPPQPQLQPPPSPQQMPPLEKARIAG----VGSLPLSGVEEKMFSLLKRAKVQLFKID 807
Query: 77 RGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGPGESEAGAGGERERRGAG 136
+ + +PL P GQ AG + R P + + + E +G E +G
Sbjct: 808 QQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQG-- 865
Query: 137 DQPETRSVCSSRSSSSG 153
P + VC + + G
Sbjct: 866 --PRIKHVCRHAAVALG 880
Score = 31.6 bits (70), Expect = 1.3
Identities = 33/99 (33%), Positives = 40/99 (40%), Gaps = 16/99 (16%)
Query: 8 GGSRCRGAESGDAEPPPQPP------PPPPPTPPPGEP----APVPAAP--RYLPPLPAS 55
GG GA + PP PP P T P +P A +P AP R L PA
Sbjct: 2122 GGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPA- 2180
Query: 56 PETPERAAGP---SEPLGEVAPRCRGADELPPPPLPLQP 91
PE P+ A LG+V + G E PPP+ P
Sbjct: 2181 PEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPP 2219
Score = 31.2 bits (69), Expect = 1.7
Identities = 44/171 (25%), Positives = 51/171 (29%), Gaps = 65/171 (38%)
Query: 22 PPPQ-----PPPPPPPTPPPGEP---------------APVPAAPRYLPPLPASPETPER 61
PPP+ P PP P GE A P APR P TP R
Sbjct: 162 PPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPR---SRACEPSTPRR 218
Query: 62 AAGPSEPLGEVAPRCRGADEL------------PPPPLPLQPAGQEVAAAGDSGEGPRRL 109
+ G P G A CR + P PP P+ P + + EGP
Sbjct: 219 SRG--RPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGS-WKCKEGP--- 272
Query: 110 PEAAAAKGGPGESEAGAGGERERRGAGDQPETRSVCSSRSSSSGGGDQRAG 160
GPG GG+ SSR G G R G
Sbjct: 273 --------GPGPGTPRRGGQ----------------SSRGGRGGRGRGRGG 299
Score = 30.4 bits (67), Expect = 3.0
Identities = 27/101 (26%), Positives = 36/101 (35%), Gaps = 26/101 (25%)
Query: 16 ESGDAEPPPQPPPPPPPTPPPGEPAPVP------------AAPRYLPPL----------- 52
ES PP P P P PPP + +P + PR+ P +
Sbjct: 663 ESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPH 722
Query: 53 --PASPETPERAAGPSEPLGEVAPRCRGADELPPPPLPLQP 91
PA P+ A +PL + + LPPP LQP
Sbjct: 723 GAPALSNGPQTQAQLLQPLQALQTQLL-PQALPPPQPQLQP 762
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 62.8 bits (151), Expect = 5e-10
Identities = 47/126 (37%), Positives = 54/126 (42%), Gaps = 32/126 (25%)
Query: 14 GAESGDAEPPPQPPP---PPPPTPPPGEPAPV---PAAPRYLPPLPASPETPERAAGPSE 67
G+ S D P +P P PPPP P PG P+P P+AP PPLP SPE P P+
Sbjct: 524 GSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPP-----PAP 578
Query: 68 PLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGP------GE 121
PL +LPPPP P P G G P P GGP +
Sbjct: 579 PL---------PGDLPPPPPPPPP------PPGTDGPVPPPPPPPPPPPGGPPDALGRRD 623
Query: 122 SEAGAG 127
SE G G
Sbjct: 624 SELGPG 629
Score = 36.2 bits (82), Expect = 0.054
Identities = 36/127 (28%), Positives = 42/127 (33%), Gaps = 33/127 (25%)
Query: 18 GDAEPPPQPPPPPP--PTPP---------------------PGEPAPVPAAP-RYLPPLP 53
G + PP+P PP PT P PG+ + P P
Sbjct: 454 GASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSG 513
Query: 54 ASPETPERAAG-PSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEA 112
TP G PS L A GA PPPPLP P+ QE P P+A
Sbjct: 514 GDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAP--------PSAPPQA 565
Query: 113 AAAKGGP 119
G P
Sbjct: 566 PPLPGSP 572
Score = 30.8 bits (68), Expect = 2.3
Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 1/29 (3%)
Query: 14 GAESGDAEPPPQPPPPPPPTP-PPGEPAP 41
G +G AE P P PPP P PP +P P
Sbjct: 2 GNAAGSAEQPAGPAAPPPKQPAPPKQPMP 30
Score = 28.9 bits (63), Expect = 8.6
Identities = 13/23 (56%), Positives = 14/23 (60%), Gaps = 1/23 (4%)
Query: 17 SGDAEPPP-QPPPPPPPTPPPGE 38
+G A PPP QP PP P P GE
Sbjct: 12 AGPAAPPPKQPAPPKQPMPAAGE 34
>gi|32307177 forkhead box G1 [Homo sapiens]
Length = 489
Score = 62.4 bits (150), Expect = 7e-10
Identities = 48/127 (37%), Positives = 55/127 (43%), Gaps = 35/127 (27%)
Query: 22 PPPQPPPPPPP----TPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPRCR 77
PPP P PPPPP PPP PAP P R P + GP + L
Sbjct: 59 PPPAPQPPPPPQQQQPPPPPPPAPQPPQTRGAP-------AADDDKGPQQLL-------- 103
Query: 78 GADELPPPPLPLQPAGQEVAAA------GDSGEGPRRLPEAAAAKGGPGESEAGAG-GER 130
LPPPP P A + A A G+ G GP L A GP E E GAG G
Sbjct: 104 ----LPPPPPPPPAAALDGAKADGLGGKGEPGGGPGEL-----APVGPDEKEKGAGAGGE 154
Query: 131 ERRGAGD 137
E++GAG+
Sbjct: 155 EKKGAGE 161
>gi|30425370 membrane-associated ring finger (C3HC4) 3 [Homo
sapiens]
Length = 253
Score = 61.2 bits (147), Expect = 2e-09
Identities = 23/55 (41%), Positives = 37/55 (67%)
Query: 167 QPICKICFQGAEQGELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELCCYRYHV 221
+P+C+IC +G+ Q +LL+PC C G++ H+ CL W+S + CELC +R+ V
Sbjct: 68 RPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCHFRFAV 122
>gi|33286436 gametogenetin [Homo sapiens]
Length = 652
Score = 59.7 bits (143), Expect = 5e-09
Identities = 49/162 (30%), Positives = 59/162 (36%), Gaps = 15/162 (9%)
Query: 3 FEGGHGGSRCRGAESGDAEPPPQPPPPPPPT--PPPGEPAPVPAAPRYLPPLPASPETPE 60
F G R G E PP PPP PPPT PP +P P+P AP P L
Sbjct: 418 FPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALA 477
Query: 61 RAAGPSEPLGEVAPRCRGADELPPPPL--PLQPAGQEVAAAGDSGEGPRRLPEAAAAKGG 118
A P+ P A + P P + P P AA RR + AA+G
Sbjct: 478 PTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGA 537
Query: 119 PGESEAGAGGERERRGAGDQPETRSVCSSRSSSSGGGDQRAG 160
+ G RER A + SSGGG +G
Sbjct: 538 TRKDGLHGDGPRERATA-----------TVPDSSGGGGGGSG 568
Score = 48.1 bits (113), Expect = 1e-05
Identities = 63/204 (30%), Positives = 71/204 (34%), Gaps = 63/204 (30%)
Query: 5 GGHGGSRCRGAE-SGDAEPPPQPPPPPPPTPPPGEPAP-VPAAPRYLPPLPASPETPERA 62
GG G R R A SG PP PP P P PAP + A P ++ P P + E P R
Sbjct: 371 GGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGE-PMRP 429
Query: 63 AGPSEPLGEVAPRCRGADELPPP-------PLPLQPAGQEVAAAGDSGEGPRR------- 108
P L E+ P LPPP P LQP VA G G +
Sbjct: 430 GPPG--LQELPP-------LPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTA 480
Query: 109 ---LPEAAAAKGGPGESEAGA---------------------------GGERERRGA--- 135
LP A AA P S A A G R RGA
Sbjct: 481 APALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRK 540
Query: 136 ----GDQPETRSVCSSRSSSSGGG 155
GD P R+ + SS GGG
Sbjct: 541 DGLHGDGPRERATATVPDSSGGGG 564
Score = 38.9 bits (89), Expect = 0.008
Identities = 40/122 (32%), Positives = 49/122 (40%), Gaps = 24/122 (19%)
Query: 22 PPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETP--ERAAGPSEPLGEVAPRCRGA 79
P PPP PPP P+ A R + P A+P +P E AGP G+ A R RG
Sbjct: 161 PSQFPPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQ-GQTAGRARGG 219
Query: 80 DELPPPPLPLQPAGQ-EVAAAGDSGEG------------PRRLPEAAAAKGGPGESEAGA 126
PP AG+ E+A DS G P P AA++ S G
Sbjct: 220 --APP------HAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGG 271
Query: 127 GG 128
GG
Sbjct: 272 GG 273
Score = 34.3 bits (77), Expect = 0.20
Identities = 53/194 (27%), Positives = 60/194 (30%), Gaps = 66/194 (34%)
Query: 18 GDAEPP-------PQPPP---------PPPPTPPPGEPAPVPAAPRYLPPLPASPETPER 61
G A PP PQ P P P PPP E A V A PP PA P
Sbjct: 53 GSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAP----PPAPAGTLLP-- 106
Query: 62 AAGPS---EPLGEVAPRCRGADE--------------LPPPPLPLQPAGQEVAAAGDSGE 104
GPS +P G PR R E L PPP P Q + ++ S
Sbjct: 107 --GPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQF 164
Query: 105 GP--------------------RRLPEAAAAKGGPGESEAGAGGE-----RERRGAGDQP 139
P R P A P ES+AG + R R GA
Sbjct: 165 PPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHA 224
Query: 140 ETRSVCSSRSSSSG 153
+ S SG
Sbjct: 225 GEGEMAQPADSESG 238
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 57.8 bits (138), Expect = 2e-08
Identities = 34/88 (38%), Positives = 36/88 (40%), Gaps = 17/88 (19%)
Query: 22 PPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPRCRGADE 81
P P PPPPPPP PPP P P P PPLP SP P P P
Sbjct: 679 PLPPPPPPPPPLPPPSSAGPPPPPPP--PPLPNSPAPPNPGGPPPAP------------- 723
Query: 82 LPPPPL-PLQPAGQEVAAAGDSGEGPRR 108
PPP L P P G S + PR+
Sbjct: 724 -PPPGLAPPPPPGLFFGLGSSSSQCPRK 750
Score = 48.1 bits (113), Expect = 1e-05
Identities = 37/107 (34%), Positives = 39/107 (36%), Gaps = 26/107 (24%)
Query: 22 PPPQPPPPPPPTPP------PGEPAPVPAAPRYLPPLPASPET--PERAAGPSEPLGEVA 73
PPP PPPPP P P P P +A LPP P P P +AGP P
Sbjct: 647 PPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPP----- 701
Query: 74 PRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGPG 120
PPPPLP P A G P P A PG
Sbjct: 702 --------PPPPPLPNSP-----APPNPGGPPPAPPPPGLAPPPPPG 735
Score = 42.7 bits (99), Expect = 6e-04
Identities = 19/40 (47%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 15 AESGDAEPPPQPPPPPPPTPP-PGEPAPVPAAPRYLPPLP 53
+ +G PPP PP P P PP PG P P P P PP P
Sbjct: 694 SSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPP 733
Score = 39.3 bits (90), Expect = 0.006
Identities = 31/95 (32%), Positives = 35/95 (36%), Gaps = 23/95 (24%)
Query: 27 PPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPRCRGADELPPPP 86
PPPP PPP P P L L +P P +AGP LPPPP
Sbjct: 646 PPPPASIPPP------PPLPSGLGSLSPAPPMPPVSAGPP---------------LPPPP 684
Query: 87 LPLQPAGQEVAAAGDSGEGPRRLPEAAAA--KGGP 119
P P +A P LP + A GGP
Sbjct: 685 PPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGP 719
Score = 36.6 bits (83), Expect = 0.041
Identities = 23/64 (35%), Positives = 28/64 (43%), Gaps = 14/64 (21%)
Query: 20 AEPPPQPPPPP-------------PPTPPPGEPAPVPAAPRYLPPLPASPETPER-AAGP 65
A PPP PPPPP PP PPP AP P + +S + P + A P
Sbjct: 696 AGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEP 755
Query: 66 SEPL 69
S P+
Sbjct: 756 SCPM 759
>gi|169167066 PREDICTED: hypothetical protein [Homo sapiens]
Length = 262
Score = 57.8 bits (138), Expect = 2e-08
Identities = 47/132 (35%), Positives = 55/132 (41%), Gaps = 15/132 (11%)
Query: 18 GDAEPPPQPPPPPPPTPPPGEPAPVPAAPRYLP------PLPASPETPERAAGPSEPL-- 69
G PPP PPPPP P PPP P P P PR L P +P+ P R S L
Sbjct: 28 GTTYPPPPPPPPPTPRPPPPPPLP-PPGPRLLRACSLLLPTEPAPDLPPRRRSSSRSLAR 86
Query: 70 GEVAPRCRGADELPPPPLP---LQPAGQEVAAAGDSGEGPRRLPEAAAA--KGGPG-ESE 123
G + A L PPP P +P + AAG +G P R + G P E
Sbjct: 87 GRITQCQVAASPLVPPPAPPHCPRPLLCFLPAAGPAGLPPLRTSPCSGVTFAGRPRLGQE 146
Query: 124 AGAGGERERRGA 135
+G G RR A
Sbjct: 147 SGQGVAARRRRA 158
>gi|113416187 PREDICTED: hypothetical protein [Homo sapiens]
Length = 262
Score = 57.8 bits (138), Expect = 2e-08
Identities = 47/132 (35%), Positives = 55/132 (41%), Gaps = 15/132 (11%)
Query: 18 GDAEPPPQPPPPPPPTPPPGEPAPVPAAPRYLP------PLPASPETPERAAGPSEPL-- 69
G PPP PPPPP P PPP P P P PR L P +P+ P R S L
Sbjct: 28 GTTYPPPPPPPPPTPRPPPPPPLP-PPGPRLLRACSLLLPTEPAPDLPPRRRSSSRSLAR 86
Query: 70 GEVAPRCRGADELPPPPLP---LQPAGQEVAAAGDSGEGPRRLPEAAAA--KGGPG-ESE 123
G + A L PPP P +P + AAG +G P R + G P E
Sbjct: 87 GRITQCQVAASPLVPPPAPPHCPRPLLCFLPAAGPAGLPPLRTSPCSGVTFAGRPRLGQE 146
Query: 124 AGAGGERERRGA 135
+G G RR A
Sbjct: 147 SGQGVAARRRRA 158
>gi|113415691 PREDICTED: hypothetical protein [Homo sapiens]
Length = 262
Score = 57.8 bits (138), Expect = 2e-08
Identities = 47/132 (35%), Positives = 55/132 (41%), Gaps = 15/132 (11%)
Query: 18 GDAEPPPQPPPPPPPTPPPGEPAPVPAAPRYLP------PLPASPETPERAAGPSEPL-- 69
G PPP PPPPP P PPP P P P PR L P +P+ P R S L
Sbjct: 28 GTTYPPPPPPPPPTPRPPPPPPLP-PPGPRLLRACSLLLPTEPAPDLPPRRRSSSRSLAR 86
Query: 70 GEVAPRCRGADELPPPPLP---LQPAGQEVAAAGDSGEGPRRLPEAAAA--KGGPG-ESE 123
G + A L PPP P +P + AAG +G P R + G P E
Sbjct: 87 GRITQCQVAASPLVPPPAPPHCPRPLLCFLPAAGPAGLPPLRTSPCSGVTFAGRPRLGQE 146
Query: 124 AGAGGERERRGA 135
+G G RR A
Sbjct: 147 SGQGVAARRRRA 158
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 57.8 bits (138), Expect = 2e-08
Identities = 28/52 (53%), Positives = 30/52 (57%), Gaps = 9/52 (17%)
Query: 22 PPPQPPPPPPPTPPPGEPAPVPA-----APRYLPPLPASPETPERAAGPSEP 68
PPP PPPPPPP PPP P P PA AP PPLP++P P G S P
Sbjct: 556 PPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAPPLP----GTSSP 603
Score = 47.0 bits (110), Expect = 3e-05
Identities = 35/94 (37%), Positives = 36/94 (38%), Gaps = 16/94 (17%)
Query: 5 GGHGGSRCRGAESGDAEPPPQPPPPPPPTP---------PPGEPAPVPAAPRYLPPLPAS 55
G G A SG PPP P PP TP PP P P P P PP P
Sbjct: 511 GNSVGPTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPP---PPPPPP 567
Query: 56 PETPERAAGPSEPLGEVAPRCRGADELP-PPPLP 88
P P GP+ E P A LP PPLP
Sbjct: 568 PPPPPPLPGPA---AETVPAPPLAPPLPSAPPLP 598
Score = 37.7 bits (86), Expect = 0.019
Identities = 32/112 (28%), Positives = 35/112 (31%), Gaps = 28/112 (25%)
Query: 14 GAESGDAEPPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVA 73
G G A P PPPPPP P P V P PP+P P P
Sbjct: 515 GPTMGAASSGPLPPPPPPLPPSSDTPETVQNGP-VTPPMPPPPPPP-------------- 559
Query: 74 PRCRGADELPPPPLPLQPAGQEVAAAGDSGE---GPRRLPEAAAAKGGPGES 122
PPP P P G + E P P +A PG S
Sbjct: 560 ----------PPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAPPLPGTS 601
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 57.0 bits (136), Expect = 3e-08
Identities = 55/164 (33%), Positives = 63/164 (38%), Gaps = 42/164 (25%)
Query: 20 AEPPPQPPPPPPPTPPPG-EPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPRCRG 78
A PPP P PP PP G AP PA PPLP P+ P A P +
Sbjct: 178 AAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPP---APPQQ----------- 223
Query: 79 ADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGPG---------------ESE 123
+ PPPP P P AG + P L E GG G E E
Sbjct: 224 --QQPPPPQPQPPPEGGAVRAGGAAR-PVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEE 280
Query: 124 AGAGG--ERERRGA-----GDQPETRSVCSSR--SSSSGGGDQR 158
A A G ER R GA GD+P +S S S GG++R
Sbjct: 281 AAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEER 324
Score = 53.9 bits (128), Expect = 2e-07
Identities = 39/108 (36%), Positives = 44/108 (40%), Gaps = 15/108 (13%)
Query: 13 RGAESGDAEPPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEV 72
RGA + A P P P PPP P P A APR +P +P GP++P
Sbjct: 116 RGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSP----GPAQP---- 167
Query: 73 APRC-RGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGP 119
PR R A PPP P P A GPRR P A A P
Sbjct: 168 GPRAQRAAPLAAPPPAPAAPPAVAPPA------GPRRAPPPAVAAREP 209
Score = 49.7 bits (117), Expect = 5e-06
Identities = 40/114 (35%), Positives = 46/114 (40%), Gaps = 8/114 (7%)
Query: 21 EPPPQPP-PPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPR-CRG 78
+PP + PP PP P G PA AA P P P P AA P+ APR
Sbjct: 100 QPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPAR-----APRAAAA 154
Query: 79 ADELPPPPLPLQPAGQEVAAAGDSGEGPR-RLPEAAAAKGGPGESEAGAGGERE 131
A PP P P QP + AA + P P A A GP + A RE
Sbjct: 155 AATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAARE 208
Score = 46.2 bits (108), Expect = 5e-05
Identities = 49/164 (29%), Positives = 61/164 (37%), Gaps = 28/164 (17%)
Query: 20 AEPPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEP--LGEVAPRCR 77
A PP PPPP PP PP + P P P P RA G + P L EV
Sbjct: 206 AREPPLPPPPQPPAPPQQQQPPPP------QPQPPPEGGAVRAGGAARPVSLREVVRYLG 259
Query: 78 GADELPPPPLPLQPAG---QEVAAAG------------DSGEGPRRLPEAAAAKGGPGES 122
G+ + G +E AA G G+ P R P AA+A+ P S
Sbjct: 260 GSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASAR--PSRS 317
Query: 123 EAGAGG---ERERRGAGDQPETRSVCSSRSSSSGGGDQRAGHQH 163
+ G E+E D+ E S S D+ AG QH
Sbjct: 318 KRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQH 361
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 56.6 bits (135), Expect = 4e-08
Identities = 49/161 (30%), Positives = 56/161 (34%), Gaps = 27/161 (16%)
Query: 8 GGSRCRGAESGDAEPPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASP----------E 57
GG R RG S PP P PPPP PPP P P P P LP L SP
Sbjct: 226 GGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPP--LPGLATSPPFQLTKPGLWS 283
Query: 58 TPERAAGPSEPLGEVAPRCRGADELPPPPLP-------LQPAGQEVAAAGDSGEGPRRLP 110
T A E G P + P P P P G + A G GPR P
Sbjct: 284 TLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPR--P 341
Query: 111 EAAAAKG------GPGESEAGAGGERERRGAGDQPETRSVC 145
A + G PG + +R R + P + C
Sbjct: 342 PGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTAC 382
Score = 42.4 bits (98), Expect = 8e-04
Identities = 37/129 (28%), Positives = 51/129 (39%), Gaps = 16/129 (12%)
Query: 19 DAEPPPQPPPPPP--PTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPRC 76
+ +PPP PPPPP PPP +P P P PP P+ + A E
Sbjct: 768 EKKPPPALPPPPPLAKFPPPSQPQPPP------PPPPSPASLLKSLASVLEGQKYCYRGT 821
Query: 77 RGADELPPPPLPL------QPAGQEVAAAGDSGEGPRRLPEAAAAKGGPGESEAGAGGER 130
A P PLP P+G + + P+ +A+ S +G R
Sbjct: 822 GAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQ-FSTSGGPWAR 880
Query: 131 ERRGAGDQP 139
ERR AG++P
Sbjct: 881 ERR-AGEEP 888
Score = 40.4 bits (93), Expect = 0.003
Identities = 52/207 (25%), Positives = 71/207 (34%), Gaps = 58/207 (28%)
Query: 22 PPPQPPPPPPPTPPPGE--------------------------PAPVP---------AAP 46
PP QP PPPPP P P P P+P +
Sbjct: 786 PPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGA 845
Query: 47 RYLPPLPASPE---TPERAAGPSEPL----GEVAPRCRGADE---------LPPPPLPLQ 90
LPP A+P +P+ +A S G A R +E PPPPL L
Sbjct: 846 TALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLP 905
Query: 91 PAGQEVAAAGDSGEGPRRLPE----AAAAKGGPGES--EAGAGGERERRGAGDQPETRSV 144
PA E + L E +A P ++ A +G ER A + E V
Sbjct: 906 PARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGV 965
Query: 145 CSSRSSSSGGGDQRAGHQHQHHQPICK 171
++ S S + +H+ H+ CK
Sbjct: 966 -AAVSGSCKRRQKEHQKEHRRHRRACK 991
Score = 36.6 bits (83), Expect = 0.041
Identities = 41/122 (33%), Positives = 44/122 (36%), Gaps = 37/122 (30%)
Query: 14 GAESGDAEPPPQPPPPP------PPTPPPGEPAPVPAAPRY------LPPLPAS------ 55
G+ S P PPPP P P P PA P P LPP P S
Sbjct: 559 GSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNT 618
Query: 56 ------PETPE-RAAGPSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRR 108
PE+P R + P P EV P PPP PL A Q V GE P R
Sbjct: 619 SGSFRRPESPRPRVSFPKTP--EVGP--------GPPPGPLSKAPQPVPPG--VGELPAR 666
Query: 109 LP 110
P
Sbjct: 667 GP 668
Score = 35.4 bits (80), Expect = 0.092
Identities = 46/176 (26%), Positives = 62/176 (35%), Gaps = 36/176 (20%)
Query: 19 DAEPPPQPPPPPP----PTPPPGEPAPVPAAPRYLPPLPASPET-----------PERAA 63
+A PQPP P +P P + AP AP + T P A
Sbjct: 716 EAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPAL 775
Query: 64 GPSEPLGEVAPRCRGADELPPPPLPLQPA-----------GQEVAAAGDS---GEGPRRL 109
P PL + P + PPPP P PA GQ+ G P L
Sbjct: 776 PPPPPLAKFPP---PSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPL 832
Query: 110 PEAAAAKGGPGESEAGAGGERERRGAGDQPETRSVCSSRSSSSGG---GDQRAGHQ 162
P + G P + A G P+ + SS+ S+SGG ++RAG +
Sbjct: 833 PTTQYSPGPPSGATALPPTSAAPSAQG-SPQPSASSSSQFSTSGGPWARERRAGEE 887
Score = 34.7 bits (78), Expect = 0.16
Identities = 29/102 (28%), Positives = 41/102 (40%), Gaps = 15/102 (14%)
Query: 8 GGSRCRGAESGDAEPPPQP----PPPPPPTPPPGEPAPVPAAPRYLPPLPASPET----- 58
GG R +G+ EP P P PPPP + PP + L + + ET
Sbjct: 875 GGPWARERRAGE-EPVPGPMTPTQPPPPLSLPPAR-----SESEVLEEISRACETLVERV 928
Query: 59 PERAAGPSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAG 100
A P++P+ P G + L PP + AG A +G
Sbjct: 929 GRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSG 970
Score = 34.3 bits (77), Expect = 0.20
Identities = 29/109 (26%), Positives = 36/109 (33%), Gaps = 16/109 (14%)
Query: 18 GDAEPPPQPPPP--PPPTPPPGEPAPVPAAPR-------------YLPPLPASPETPERA 62
G + PPP P P PP PP P A R PP PA P P R
Sbjct: 464 GPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHRE 523
Query: 63 AGPSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAA-GDSGEGPRRLP 110
P + + + P PP P + + + S GP P
Sbjct: 524 GFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFP 572
Score = 34.3 bits (77), Expect = 0.20
Identities = 45/184 (24%), Positives = 55/184 (29%), Gaps = 60/184 (32%)
Query: 9 GSRCRGA-ESGD--------AEPPPQPPPPP------------------------PPTPP 35
G CR A E G+ E PP+P PPP PPTPP
Sbjct: 488 GPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPP 547
Query: 36 P----------GEPAPVPAAPRYLPPLP-------ASPETPERAAGPSEPLGEVAPRCRG 78
G + PA P PP P P P A P +P + P
Sbjct: 548 TPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDP--PLVPL--- 602
Query: 79 ADELPPPPLPLQPAGQEVAAAGDSGEGPR---RLPEAAAAKGGPGESEAGAGGERERRGA 135
L PP P Q + + E PR P+ GP + G
Sbjct: 603 --TLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV 660
Query: 136 GDQP 139
G+ P
Sbjct: 661 GELP 664
Score = 33.1 bits (74), Expect = 0.46
Identities = 35/120 (29%), Positives = 44/120 (36%), Gaps = 17/120 (14%)
Query: 20 AEPPPQPPPPPPPTPPPGEPAPVPAAPRYL--PPLPASPETP--ERAAGPSEPLGEVAPR 75
A P PP P +PPP P PR L PP PA + P A E L E+
Sbjct: 454 AATPHLSLPPGPSSPPP------PPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFG 507
Query: 76 CRGADELPPPPLPLQ------PAGQEVAAAGDSGEGPR-RLPEAAAAKGGPGESEAGAGG 128
G PPPLP + PA + DS P P +++ G + G
Sbjct: 508 TEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAG 567
Score = 32.3 bits (72), Expect = 0.78
Identities = 37/117 (31%), Positives = 41/117 (35%), Gaps = 25/117 (21%)
Query: 8 GGSRCRGAESG-DAEPPP---------------QPPPPPPPTPPPGEPAPVPAAPRYLPP 51
GG C GA S PPP QPP P P P G + P+ P Y P
Sbjct: 20 GGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPLPPSHGSSSGHPSKPYYAPG 79
Query: 52 LPASPETPERAAGPSEPL-GEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPR 107
P TP G E L G V R P P + GQ + DS E R
Sbjct: 80 AP----TPRPLHGKLESLHGCVQALLRE----PAQPGLWEQLGQLYESEHDSEEATR 128
Score = 30.4 bits (67), Expect = 3.0
Identities = 26/98 (26%), Positives = 38/98 (38%), Gaps = 4/98 (4%)
Query: 50 PPLPASPETPERAAGPSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRL 109
P PA P P +A P+ P V P + +E P PP + ++ EGP +
Sbjct: 1047 PTAPAPPSAPAPSAQPTPPSASV-PGKKAREEAPGPP---GVSRADMLKLRSLSEGPPKE 1102
Query: 110 PEAAAAKGGPGESEAGAGGERERRGAGDQPETRSVCSS 147
+ K G+ E E E R T S C++
Sbjct: 1103 LKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA 1140
>gi|22027541 programmed cell death 7 [Homo sapiens]
Length = 485
Score = 56.6 bits (135), Expect = 4e-08
Identities = 42/119 (35%), Positives = 49/119 (41%), Gaps = 13/119 (10%)
Query: 18 GDAEPPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGP-SEPLGEVAPRC 76
G P P PPP PPP P G P P +P + PPLP P A+ P +P + PR
Sbjct: 8 GQGRPGP-PPPQPPPPAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRA 66
Query: 77 -----RGAD------ELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGPGESEA 124
RG +PPPPLP P D+GE PR P P EA
Sbjct: 67 SAEASRGGGGAGAFYPVPPPPLPPPPPQCRPFPGTDAGERPRPPPPGPGPPWSPRWPEA 125
Score = 45.4 bits (106), Expect = 9e-05
Identities = 36/115 (31%), Positives = 40/115 (34%), Gaps = 50/115 (43%)
Query: 22 PPPQPPPP------PPPTPPPGEPAPVP---------AAPRYLPPLPASPETPERAAG-- 64
PPPQPPPP PPP P P P P+P +AP PPL P A+
Sbjct: 15 PPPQPPPPAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRASAEASRGG 74
Query: 65 ---------PSEPLGEVAPRCR---GAD---------------------ELPPPP 86
P PL P+CR G D E PPPP
Sbjct: 75 GGAGAFYPVPPPPLPPPPPQCRPFPGTDAGERPRPPPPGPGPPWSPRWPEAPPPP 129
Score = 40.0 bits (92), Expect = 0.004
Identities = 25/64 (39%), Positives = 29/64 (45%), Gaps = 4/64 (6%)
Query: 14 GAESGDAEPPPQPP-PPPPPTPPPGEPAPVPAAPRYLPPLPA---SPETPERAAGPSEPL 69
G +G P P PP PPPPP P PR PP P SP PE P++ L
Sbjct: 74 GGGAGAFYPVPPPPLPPPPPQCRPFPGTDAGERPRPPPPGPGPPWSPRWPEAPPPPADVL 133
Query: 70 GEVA 73
G+ A
Sbjct: 134 GDAA 137
Score = 31.6 bits (70), Expect = 1.3
Identities = 39/111 (35%), Positives = 42/111 (37%), Gaps = 23/111 (20%)
Query: 11 RCRGAESGDAEPPPQPPPP--PPPTPPPGEPAPVPAAP----------RYLPPLPASPET 58
+CR DA P+PPPP PP P AP P A R L A T
Sbjct: 94 QCRPFPGTDAGERPRPPPPGPGPPWSPRWPEAPPPPADVLGDAALQRLRDRQWLEAVFGT 153
Query: 59 PERA---------AGPSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAG 100
P RA AGPS LGEV R A L L A +E A G
Sbjct: 154 PRRAGCPVPQRTHAGPS--LGEVRARLLRALRLVRRLRGLSQALREAEADG 202
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 55.8 bits (133), Expect = 7e-08
Identities = 43/126 (34%), Positives = 50/126 (39%), Gaps = 15/126 (11%)
Query: 14 GAESGDAEPPPQPPPPPP----PTPPP----GEP-APVPAAPRYLPP-----LPASPETP 59
G + G A PP PPPPPP P PPP G P P P +P PP P P P
Sbjct: 311 GPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPP 370
Query: 60 ERAAGPSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGG- 118
A P+ P ++ GA PPPP P P A P L + K
Sbjct: 371 PAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSL 430
Query: 119 PGESEA 124
P S+A
Sbjct: 431 PAVSDA 436
Score = 45.4 bits (106), Expect = 9e-05
Identities = 38/103 (36%), Positives = 43/103 (41%), Gaps = 27/103 (26%)
Query: 13 RGAESGDAEPPPQPP---PP-------PPPTPPP------GEPAPVP----AAPRYLPP- 51
R + + PPP PP PP PPP PPP G P P P +P PP
Sbjct: 291 RSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPP 350
Query: 52 -LPASPETPERAAGPSEPLGEVAPRCRGADELPPPPLPLQPAG 93
P+ P P+ AA P P P LPPPPL QP G
Sbjct: 351 SPPSFPPHPDFAAPPPPP----PPPAADYPTLPPPPLS-QPTG 388
Score = 45.1 bits (105), Expect = 1e-04
Identities = 38/132 (28%), Positives = 44/132 (33%), Gaps = 12/132 (9%)
Query: 9 GSRCRGAESGDAEPPPQPPPPPPPTPPPG-------EPAPVPAAPRYL----PPLPASPE 57
GS G + P PPP PP PPG PAP P P + PP P
Sbjct: 283 GSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFG 342
Query: 58 TPERAAGPSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKG 117
+P PS P P PPPP P + +G P P G
Sbjct: 343 SPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPP-PPPPPPPG 401
Query: 118 GPGESEAGAGGE 129
P GA G+
Sbjct: 402 PPPPPFTGADGQ 413
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 55.8 bits (133), Expect = 7e-08
Identities = 45/140 (32%), Positives = 55/140 (39%), Gaps = 21/140 (15%)
Query: 14 GAESGDAEPPPQPP---PPPPPTPPPG---EPAPVPAAPRYLPPLPASPE--TPERAAGP 65
G S ++ P+PP PPPTPPP +P P P P P LP+ P P ++ P
Sbjct: 1438 GLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPP 1497
Query: 66 SEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPR----------RLPEAAAA 115
PL P + PPPP A A S E P + E AA
Sbjct: 1498 PPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAV 1557
Query: 116 KGGPGESEAGAGGE---RER 132
G E +GGE RER
Sbjct: 1558 CGETDEEAGESGGEGIFRER 1577
Score = 52.0 bits (123), Expect = 9e-07
Identities = 51/177 (28%), Positives = 64/177 (36%), Gaps = 20/177 (11%)
Query: 1 MSFEGGHGGSRCRGAESGDAEPPPQPPPPPPPTPPP-----------GEPAPVPAAPRYL 49
+ FE GG A G A+ PP P PP P PPP A AA +
Sbjct: 203 LGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSS 262
Query: 50 PPL------PASPETPERAAGPSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSG 103
P L P PERA + + + R A PPPP P A Q + G S
Sbjct: 263 PQLYNFSGAAPGPPPPERALPRQDTV--IKHYQRPASAQPPPPPPPAHALQHYLSCGGSY 320
Query: 104 EGPRRLPEAAAAKGGPGESEAGAGGERERRGAGDQPETRSVCSSRSSSSGGGDQRAG 160
A + G GE GA GE + G S ++ ++GGG G
Sbjct: 321 PSMGHRANLACSPLGGGEPSPGA-GEPSKAGPSGATAGASGRATGPEAAGGGGAGGG 376
Score = 43.5 bits (101), Expect = 3e-04
Identities = 30/91 (32%), Positives = 37/91 (40%), Gaps = 14/91 (15%)
Query: 16 ESGDAEPPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPR 75
E + PQPPPPPP PPP P + A R PA+P R +P G +
Sbjct: 825 EPATRDGAPQPPPPPP-PPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQEL 883
Query: 76 CRGADELPPPPLPLQPAGQEVAAAGDSGEGP 106
+ LPP P GD+G GP
Sbjct: 884 LGALEPLPPAP-------------GDTGVGP 901
Score = 43.1 bits (100), Expect = 4e-04
Identities = 50/173 (28%), Positives = 61/173 (35%), Gaps = 27/173 (15%)
Query: 27 PPPPPPTPPPGEPAP--------VPAAPRYLPPLPAS--PETPERAAGPSEPLGEVA--- 73
PPPPPPT +P P P P LPP P P A PS +V
Sbjct: 764 PPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHL 823
Query: 74 --PRCR-GADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGPGESEAGAGGER 130
P R GA + PPPP P P A G P A + + P ES G +
Sbjct: 824 LEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLE--PAAPSPRLRPEESLDPPGAMQ 881
Query: 131 ERRGAGDQ-PETRSVCSSRSSSSGGGDQRAGHQHQHHQ--------PICKICF 174
E GA + P +S G D ++ Q P+ ICF
Sbjct: 882 ELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICF 934
Score = 39.7 bits (91), Expect = 0.005
Identities = 33/89 (37%), Positives = 35/89 (39%), Gaps = 15/89 (16%)
Query: 18 GDAEPPPQPPPPPPPT-PPPGEPAPVPAAPRYLPPLP--ASPETPERAAGPS-------- 66
G A PP P PPPG PA P P Y P A PETP P+
Sbjct: 963 GKAGPPEDEGDPKAGAGPPPGPPAYDPYGP-YCPGRASGAGPETPGLGLDPNKPPELPST 1021
Query: 67 ---EPLGEVAPRCRGADELPPPPLPLQPA 92
EPLG + A PPPP P PA
Sbjct: 1022 VNAEPLGLIQSGPHQAAPPPPPPPPPPPA 1050
Score = 39.7 bits (91), Expect = 0.005
Identities = 42/170 (24%), Positives = 52/170 (30%), Gaps = 49/170 (28%)
Query: 15 AESGDAEPPPQPPPPPPPTPP-------PGEPAPVPAAPRYLPPLPASPE---------- 57
A A PP P PPP P P P E P A P PP P P
Sbjct: 1686 AGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPE--PPAPEKPSLLRPVEKEKE 1743
Query: 58 ----------------------TPERAAGPSEPLGEVAPRCRGAD-ELPPPPLPLQPAGQ 94
PER+ +P P+ R + PPP + +
Sbjct: 1744 KEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLK 1803
Query: 95 EVAAAGDSGEGPRRLPEAAAAKGGPGESEAGAGGERERRGAGDQPETRSV 144
E +G GP ES GA E ER G +TR++
Sbjct: 1804 EAGGNATAGGGP-------PGSSSDSESSPGAPSEDERAVPGRLLKTRAM 1846
Score = 39.3 bits (90), Expect = 0.006
Identities = 44/144 (30%), Positives = 51/144 (35%), Gaps = 34/144 (23%)
Query: 25 QPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPRCRGADELPP 84
QPPPPPPP A YL + P RA PLG P GA E
Sbjct: 299 QPPPPPPPAH---------ALQHYLSCGGSYPSMGHRANLACSPLGGGEPS-PGAGE--- 345
Query: 85 PPLPLQPAGQEVAA--------------AGDSGEGPRRLPEAAAAKGGPGESEAGAGGER 130
P P+G A AG G G R + ++ K G G A AG
Sbjct: 346 -PSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAG--- 401
Query: 131 ERRGAGDQPETRSVCSSRSSSSGG 154
GA P RS + + S GG
Sbjct: 402 ---GATRPPPPRSTATPKCQSLGG 422
Score = 38.5 bits (88), Expect = 0.011
Identities = 42/156 (26%), Positives = 49/156 (31%), Gaps = 32/156 (20%)
Query: 20 AEPPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVA------ 73
A P P P P P G P P P PP P TP+ P P + A
Sbjct: 1429 AVPGPPPLPGLPSANSNGTPEP-PLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPP 1487
Query: 74 -----PRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGPGESEAGAGG 128
P LPPPP P P+ P P AAA P E A
Sbjct: 1488 LVAPTPSSPPPPPLPPPPPPAMPS------------PPPPPPPAAAPLAAPPEEPAAPSP 1535
Query: 129 E------RERRGAGDQPETRSVCSSRSSSSG--GGD 156
E + ET +VC +G GG+
Sbjct: 1536 EDPELPDTRPLHLAKKQETAAVCGETDEEAGESGGE 1571
Score = 38.1 bits (87), Expect = 0.014
Identities = 28/76 (36%), Positives = 32/76 (42%), Gaps = 4/76 (5%)
Query: 21 EPPPQPPPPPPPTP--PPGEPAPVPAAPRYLPPLPA--SPETPERAAGPSEPLGEVAPRC 76
+ PP P TP PP PA P LP LP+ S TPE +P P
Sbjct: 1406 DDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAP 1465
Query: 77 RGADELPPPPLPLQPA 92
+ PPPP P QPA
Sbjct: 1466 TPQPQPPPPPPPPQPA 1481
Score = 35.4 bits (80), Expect = 0.092
Identities = 44/179 (24%), Positives = 55/179 (30%), Gaps = 73/179 (40%)
Query: 20 AEPPPQPPPPPPPTP----------------------------------PPGE------- 38
A PPP PPPPPPP P PP +
Sbjct: 1037 AAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYA 1096
Query: 39 --------------PAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPRCRGADELPP 84
PA + PR LP L +S R+ PLG++ D PP
Sbjct: 1097 QEYEFEADEDKADVPADIRLNPRRLPDLVSSC----RSRPALSPLGDI-------DFCPP 1145
Query: 85 PPLPLQP--AGQEVAAAGDSGE-----GPRRLPEAAAAKGGPGESEAGAGGERERRGAG 136
P P P G++ A G PR P GP + G ++ RG G
Sbjct: 1146 NPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRG 1204
Score = 35.0 bits (79), Expect = 0.12
Identities = 48/169 (28%), Positives = 58/169 (34%), Gaps = 39/169 (23%)
Query: 6 GHGGSRCRGAESGDAEP--PPQPPPPPPP---------TPP---------PGEPAPVPAA 45
G GG + + + PPQPP PPP +P GEP P PAA
Sbjct: 460 GFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAA 519
Query: 46 PRYLPPLPASPETPERAAGPSEPL----GEVAPRCRGADELPPP-----PLPLQPAGQEV 96
+ LP + + + G S L G P G P PL PA
Sbjct: 520 --HSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRP 577
Query: 97 AAAGDSGEGPRRLPEAAA-----AKGGPGESEAGAGGERERRGAGDQPE 140
G G + L A A G G AGAGG +G GD E
Sbjct: 578 PGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGG---YKGKGDGSE 623
Score = 33.9 bits (76), Expect = 0.27
Identities = 28/111 (25%), Positives = 39/111 (35%), Gaps = 18/111 (16%)
Query: 29 PPPPTPPPGEPA-PVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPRCRGADELPPPPL 87
PP P G+ PV A PP P +P P + P + E P +P PP
Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPP-PKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPA 1728
Query: 88 PLQPA----------------GQEVAAAGDSGEGPRRLPEAAAAKGGPGES 122
P +P+ G+ + G + PE + A G P S
Sbjct: 1729 PEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATS 1779
Score = 30.4 bits (67), Expect = 3.0
Identities = 11/23 (47%), Positives = 11/23 (47%)
Query: 14 GAESGDAEPPPQPPPPPPPTPPP 36
G PPP PPPPP P P
Sbjct: 1033 GPHQAAPPPPPPPPPPPAPASEP 1055
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 55.1 bits (131), Expect = 1e-07
Identities = 29/69 (42%), Positives = 30/69 (43%), Gaps = 22/69 (31%)
Query: 23 PPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPRCRGADEL 82
PP PPPPPPP P PG P P P P PP PA P A +
Sbjct: 688 PPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHP----------------------AVTV 725
Query: 83 PPPPLPLQP 91
PPPPLP P
Sbjct: 726 PPPPLPAPP 734
Score = 44.7 bits (104), Expect = 2e-04
Identities = 26/54 (48%), Positives = 26/54 (48%), Gaps = 8/54 (14%)
Query: 22 PPPQPPPP----PPPTPPPGEPAPVPAAPRYL---PPLPASPETPERAAGPSEP 68
PPP PP P PPP PPP P P PA P PPLPA P P P P
Sbjct: 694 PPPPPPQPGFPMPPPLPPP-PPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLP 746
Score = 43.1 bits (100), Expect = 4e-04
Identities = 33/88 (37%), Positives = 38/88 (43%), Gaps = 18/88 (20%)
Query: 20 AEPPPQPP-PPPPPTPPPGEPAPVPAAPRYLP-PLPASPETPERAAGPSEPLGEVA---- 73
A PPP PP PPPPP PPP EP +P P A P P +E E+A
Sbjct: 1538 APPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRG 1597
Query: 74 -----PRCRGADELPP-------PPLPL 89
P+ R D +PP PP PL
Sbjct: 1598 PWRRPPKKRHEDLVPPAGSPELSPPQPL 1625
Score = 42.4 bits (98), Expect = 8e-04
Identities = 25/83 (30%), Positives = 33/83 (39%), Gaps = 9/83 (10%)
Query: 21 EPPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPRCRGAD 80
+PP PP PP P PP EP A+ +PP P + + P G L A
Sbjct: 1279 QPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSL---------AK 1329
Query: 81 ELPPPPLPLQPAGQEVAAAGDSG 103
+P P G+ + G SG
Sbjct: 1330 SQSTETVPATPGGEPPLSGGSSG 1352
Score = 41.2 bits (95), Expect = 0.002
Identities = 23/41 (56%), Positives = 23/41 (56%), Gaps = 7/41 (17%)
Query: 22 PPPQPPPPPP----PTPPPGEPAP--VPAAPRYLPPLPASP 56
PPP PPPPP PPP PAP VP P LPPLP P
Sbjct: 710 PPPPPPPPPAHPAVTVPPPPLPAPPGVPPPP-ILPPLPPFP 749
Score = 35.8 bits (81), Expect = 0.070
Identities = 39/143 (27%), Positives = 47/143 (32%), Gaps = 23/143 (16%)
Query: 5 GGHGGSRCRG--AESGDAEPPPQPPPPPPPTPPPG-----EPAPVPAAPRYLPPLPASPE 57
GG GGS A+ D+ PPP TP PG P P A + PP P P
Sbjct: 358 GGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVA--HFPPPPEEPT 415
Query: 58 TPE----------RAAGPSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPR 107
R A PL P + PP P P E+ G
Sbjct: 416 ATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWS-- 473
Query: 108 RLPEAAAAKGGPGESEAGAGGER 130
PE + G P + AG E+
Sbjct: 474 --PEPCDSPGTPTLESSPAGPEK 494
Score = 32.3 bits (72), Expect = 0.78
Identities = 28/91 (30%), Positives = 32/91 (35%), Gaps = 22/91 (24%)
Query: 22 PPPQPPP----PPPPTPPPGEPAPVPAA------PRYLPP-----------LPASPETPE 60
PP P P PPP PG P P + P PP LP P+TP
Sbjct: 1458 PPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPV 1517
Query: 61 RAAGPSEPLGEVAPRCRGADELPPPPLPLQP 91
+ +P PPPPLP QP
Sbjct: 1518 FPS-THDPRTVTLDFRNAGIPAPPPPLPPQP 1547
Score = 31.2 bits (69), Expect = 1.7
Identities = 14/30 (46%), Positives = 16/30 (53%)
Query: 23 PPQPPPPPPPTPPPGEPAPVPAAPRYLPPL 52
PP P P PP PPP P+P P L P+
Sbjct: 726 PPPPLPAPPGVPPPPILPPLPPFPPGLFPV 755
>gi|53729334 membrane-associated ring finger (C3HC4) 2 isoform 2
[Homo sapiens]
Length = 176
Score = 54.7 bits (130), Expect = 1e-07
Identities = 22/48 (45%), Positives = 30/48 (62%)
Query: 168 PICKICFQGAEQGELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELC 215
P C+IC +GA LL+PC C G++ H+ CL KW+S + CELC
Sbjct: 62 PFCRICHEGANGECLLSPCGCTGTLGAVHKSCLEKWLSSSNTSYCELC 109
>gi|53729332 membrane-associated ring finger (C3HC4) 2 isoform 1
[Homo sapiens]
Length = 246
Score = 54.7 bits (130), Expect = 1e-07
Identities = 22/48 (45%), Positives = 30/48 (62%)
Query: 168 PICKICFQGAEQGELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELC 215
P C+IC +GA LL+PC C G++ H+ CL KW+S + CELC
Sbjct: 62 PFCRICHEGANGECLLSPCGCTGTLGAVHKSCLEKWLSSSNTSYCELC 109
>gi|53729330 membrane-associated ring finger (C3HC4) 2 isoform 1
[Homo sapiens]
Length = 246
Score = 54.7 bits (130), Expect = 1e-07
Identities = 22/48 (45%), Positives = 30/48 (62%)
Query: 168 PICKICFQGAEQGELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELC 215
P C+IC +GA LL+PC C G++ H+ CL KW+S + CELC
Sbjct: 62 PFCRICHEGANGECLLSPCGCTGTLGAVHKSCLEKWLSSSNTSYCELC 109
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 54.3 bits (129), Expect = 2e-07
Identities = 45/148 (30%), Positives = 58/148 (39%), Gaps = 27/148 (18%)
Query: 17 SGDAEPPPQPPPPPPPTPPPGEPAPVPAAP------RYLPPLPASPETPERA------AG 64
SG PPP PPPP PPG P+P P LPA+P+ P R+ +G
Sbjct: 354 SGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSG 413
Query: 65 PSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEG----------PRRLPEAAA 114
P PL P GA PPP ++ Q+ + D E P P
Sbjct: 414 PRPPLPPDRPSA-GAPPPPPPSTSIRNGFQD-SPCEDEWESRFYFHPISDLPPPEPYVQT 471
Query: 115 AKGGPGE---SEAGAGGERERRGAGDQP 139
K P + +E+ +G R RGA P
Sbjct: 472 TKSYPSKLARNESRSGSNRRERGAPPLP 499
Score = 43.9 bits (102), Expect = 3e-04
Identities = 32/123 (26%), Positives = 43/123 (34%), Gaps = 36/123 (29%)
Query: 8 GGSRCRGAESGDAEP----PPQPPPP-------PPPTPPP--------GEPAPVPAAPRY 48
GG R + + P PP PP P PPP PPP E P P
Sbjct: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNN 290
Query: 49 LPPLPASPETPERAAGPSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRR 108
PP+P++P + P PPPP P +P + + + R
Sbjct: 291 KPPVPSTPRPSASSQAP-----------------PPPPPPSRPGPPPLPPSSSGNDETPR 333
Query: 109 LPE 111
LP+
Sbjct: 334 LPQ 336
Score = 42.7 bits (99), Expect = 6e-04
Identities = 38/131 (29%), Positives = 49/131 (37%), Gaps = 31/131 (23%)
Query: 17 SGDAEPPPQPPPPPPPTPPPGEPA-----PVPAAPR-------YLPPLP----ASPETPE 60
S ++ PP PPPP P PPP P+ P P+ PPLP + P P
Sbjct: 301 SASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360
Query: 61 RAAGPSEPLGEVAPRCRGADELPPPP-----------LPLQPAGQEVAAAGDSGEGPR-R 108
+ P P+ + R + LPPPP LP P + GPR
Sbjct: 361 PSERPPPPVRDPPGR---SGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPP 417
Query: 109 LPEAAAAKGGP 119
LP + G P
Sbjct: 418 LPPDRPSAGAP 428
Score = 40.8 bits (94), Expect = 0.002
Identities = 29/84 (34%), Positives = 34/84 (40%), Gaps = 11/84 (13%)
Query: 26 PPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPRCRGADELPPP 85
PPPPP PP P P+A PP P P P GP + P G DE P
Sbjct: 283 PPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRP----GPP----PLPPSSSGNDETPRL 334
Query: 86 P---LPLQPAGQEVAAAGDSGEGP 106
P L L + + + G SG P
Sbjct: 335 PQRNLSLSSSTPPLPSPGRSGPLP 358
Score = 40.0 bits (92), Expect = 0.004
Identities = 32/114 (28%), Positives = 38/114 (33%), Gaps = 39/114 (34%)
Query: 14 GAESGDAEPPPQPPPPPPP---TPPPGEPAPVPAAPRYL---------PPLPASPETPER 61
G SG EP PPP P + P P PVP+ PR + PP+P P P
Sbjct: 156 GHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSP 215
Query: 62 AAGP-----------------SEPLGEVAP----------RCRGADELPPPPLP 88
P PL +P R D+ PPPP P
Sbjct: 216 GPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPP 269
Score = 35.0 bits (79), Expect = 0.12
Identities = 39/144 (27%), Positives = 47/144 (32%), Gaps = 32/144 (22%)
Query: 19 DAEPPPQP----PPPP-----------P-PTPPPGEPAPVPAAPR-----YLPPLPASPE 57
+A PPP P PP P P P PPP P P P P P LP
Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNL 339
Query: 58 TPERAAGPSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKG 117
+ + P G P E PPPP+ P G SG P P ++
Sbjct: 340 SLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPP--------GRSGPLP---PPPPVSRN 388
Query: 118 GPGESEAGAGGERERRGAGDQPET 141
G A + R D P +
Sbjct: 389 GSTSRALPATPQLPSRSGVDSPRS 412
Score = 33.9 bits (76), Expect = 0.27
Identities = 31/124 (25%), Positives = 45/124 (36%), Gaps = 18/124 (14%)
Query: 23 PPQPPPPPPPTPPPG-----------EPAPVPAAPRY--LPPLPASPE--TPERAAGPSE 67
P QP P P P P PG +P+ ++ + PPLP +P ++ P
Sbjct: 210 PRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPP 269
Query: 68 PLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGPGESEAGAG 127
P+G P PPPP +P S + P P ++ GP +
Sbjct: 270 PVGN-RPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP--PPPPPSRPGPPPLPPSSS 326
Query: 128 GERE 131
G E
Sbjct: 327 GNDE 330
Score = 30.4 bits (67), Expect = 3.0
Identities = 37/133 (27%), Positives = 47/133 (35%), Gaps = 13/133 (9%)
Query: 24 PQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLGEVAPRCRGADELP 83
P PPPP PP PP A P L + + A G+ + D
Sbjct: 2 PVPPPPAPPPPP-----TFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDR-- 54
Query: 84 PPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGPGESEAGAGGERERRG--AGDQPET 141
P+ +P G A AG G G GG G G GG G P+
Sbjct: 55 SAPILDKPKG---AGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKL 111
Query: 142 RSVCSSRSSSSGG 154
RS ++R + SGG
Sbjct: 112 RST-ANRDNDSGG 123
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.443
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,704,790
Number of Sequences: 37866
Number of extensions: 1657798
Number of successful extensions: 64018
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1317
Number of HSP's successfully gapped in prelim test: 1730
Number of HSP's that attempted gapping in prelim test: 17024
Number of HSP's gapped (non-prelim): 20485
length of query: 402
length of database: 18,247,518
effective HSP length: 105
effective length of query: 297
effective length of database: 14,271,588
effective search space: 4238661636
effective search space used: 4238661636
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.