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Search of human proteins with 154813199
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154813199 poly (ADP-ribose) polymerase family, member 14
[Homo sapiens]
(1801 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154813199 poly (ADP-ribose) polymerase family, member 14 [Hom... 3602 0.0
gi|165377137 poly (ADP-ribose) polymerase family, member 15 isof... 390 e-108
gi|22749259 poly (ADP-ribose) polymerase family, member 15 isofo... 283 8e-76
gi|226371718 poly (ADP-ribose) polymerase family, member 9 isofo... 224 4e-58
gi|226371716 poly (ADP-ribose) polymerase family, member 9 isofo... 224 4e-58
gi|226371714 poly (ADP-ribose) polymerase family, member 9 isofo... 224 4e-58
gi|226371712 poly (ADP-ribose) polymerase family, member 9 isofo... 224 4e-58
gi|226371710 poly (ADP-ribose) polymerase family, member 9 isofo... 224 4e-58
gi|226371706 poly (ADP-ribose) polymerase family, member 9 isofo... 224 4e-58
gi|157738665 poly (ADP-ribose) polymerase family, member 10 [Hom... 133 2e-30
gi|38524594 TCDD-inducible poly(ADP-ribose) polymerase [Homo sap... 131 7e-30
gi|12232413 poly ADP-ribose polymerase 12 [Homo sapiens] 128 4e-29
gi|194328777 poly (ADP-ribose) polymerase family, member 11 [Hom... 117 1e-25
gi|27477136 zinc finger antiviral protein isoform 1 [Homo sapiens] 85 7e-16
gi|13569840 MACRO domain containing 1 [Homo sapiens] 84 1e-15
gi|20336746 H2A histone family, member Y isoform 1 [Homo sapiens] 79 3e-14
gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens] 75 8e-13
gi|4758496 H2A histone family, member Y isoform 2 [Homo sapiens] 73 2e-12
gi|93141020 H2A histone family, member Y isoform 2 [Homo sapiens] 73 2e-12
gi|93141018 H2A histone family, member Y isoform 3 [Homo sapiens] 73 2e-12
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 63 3e-09
gi|8923920 H2A histone family, member Y2 [Homo sapiens] 61 9e-09
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 54 1e-06
gi|207450721 ganglioside induced differentiation associated prot... 52 5e-06
gi|8923143 ganglioside induced differentiation associated protei... 52 5e-06
gi|19923717 deltex 3-like [Homo sapiens] 46 4e-04
gi|188219599 N-myc and STAT interactor [Homo sapiens] 44 0.001
gi|116686122 kinesin family member 4 [Homo sapiens] 42 0.007
gi|150010604 kinesin family member 4B [Homo sapiens] 40 0.020
gi|158634482 poly (ADP-ribose) polymerase family, member 3 isofo... 40 0.020
>gi|154813199 poly (ADP-ribose) polymerase family, member 14 [Homo
sapiens]
Length = 1801
Score = 3602 bits (9340), Expect = 0.0
Identities = 1801/1801 (100%), Positives = 1801/1801 (100%)
Query: 1 MAVPGSFPLLVEGSWGPDPPKNLNTKLQMYFQSPKRSGGGECEVRQDPRSPSRFLVFFYP 60
MAVPGSFPLLVEGSWGPDPPKNLNTKLQMYFQSPKRSGGGECEVRQDPRSPSRFLVFFYP
Sbjct: 1 MAVPGSFPLLVEGSWGPDPPKNLNTKLQMYFQSPKRSGGGECEVRQDPRSPSRFLVFFYP 60
Query: 61 EDVRQKVLERKNHELVWQGKGTFKLTVQLPATPDEIDHVFEEELLTKESKTKEDVKEPDV 120
EDVRQKVLERKNHELVWQGKGTFKLTVQLPATPDEIDHVFEEELLTKESKTKEDVKEPDV
Sbjct: 61 EDVRQKVLERKNHELVWQGKGTFKLTVQLPATPDEIDHVFEEELLTKESKTKEDVKEPDV 120
Query: 121 SEELDTKLPLDGGLDKMEDIPEECENISSLVAFENLKANVTDIMLILLVENISGLSNDDF 180
SEELDTKLPLDGGLDKMEDIPEECENISSLVAFENLKANVTDIMLILLVENISGLSNDDF
Sbjct: 121 SEELDTKLPLDGGLDKMEDIPEECENISSLVAFENLKANVTDIMLILLVENISGLSNDDF 180
Query: 181 QVEIIRDFDVAVVTFQKHIDTIRFVDDCTKHHSIKQLQLSPRLLEVTNTIRVENLPPGAD 240
QVEIIRDFDVAVVTFQKHIDTIRFVDDCTKHHSIKQLQLSPRLLEVTNTIRVENLPPGAD
Sbjct: 181 QVEIIRDFDVAVVTFQKHIDTIRFVDDCTKHHSIKQLQLSPRLLEVTNTIRVENLPPGAD 240
Query: 241 DYSLKLFFENPYNGGGRVANVEYFPEESSALIEFFDRKVLDTIMATKLDFNKMPLSVFPY 300
DYSLKLFFENPYNGGGRVANVEYFPEESSALIEFFDRKVLDTIMATKLDFNKMPLSVFPY
Sbjct: 241 DYSLKLFFENPYNGGGRVANVEYFPEESSALIEFFDRKVLDTIMATKLDFNKMPLSVFPY 300
Query: 301 YASLGTALYGKEKPLIKLPAPFEESLDLPLWKFLQKKNHLIEEINDEMRRCHCELTWSQL 360
YASLGTALYGKEKPLIKLPAPFEESLDLPLWKFLQKKNHLIEEINDEMRRCHCELTWSQL
Sbjct: 301 YASLGTALYGKEKPLIKLPAPFEESLDLPLWKFLQKKNHLIEEINDEMRRCHCELTWSQL 360
Query: 361 SGKVTIRPAATLVNEGRPRIKTWQADTSTTLSSIRSKYKVNPIKVDPTMWDTIKNDVKDD 420
SGKVTIRPAATLVNEGRPRIKTWQADTSTTLSSIRSKYKVNPIKVDPTMWDTIKNDVKDD
Sbjct: 361 SGKVTIRPAATLVNEGRPRIKTWQADTSTTLSSIRSKYKVNPIKVDPTMWDTIKNDVKDD 420
Query: 421 RILIEFDTLKEMVILAGKSEDVQSIEVQVRELIESTTQKIKREEQSLKEKMIISPGRYFL 480
RILIEFDTLKEMVILAGKSEDVQSIEVQVRELIESTTQKIKREEQSLKEKMIISPGRYFL
Sbjct: 421 RILIEFDTLKEMVILAGKSEDVQSIEVQVRELIESTTQKIKREEQSLKEKMIISPGRYFL 480
Query: 481 LCHSSLLDHLLTECPEIEICYDRVTQHLCLKGPSADVYKAKCEIQEKVYTMAQKNIQVSP 540
LCHSSLLDHLLTECPEIEICYDRVTQHLCLKGPSADVYKAKCEIQEKVYTMAQKNIQVSP
Sbjct: 481 LCHSSLLDHLLTECPEIEICYDRVTQHLCLKGPSADVYKAKCEIQEKVYTMAQKNIQVSP 540
Query: 541 EIFQFLQQVNWKEFSKCLFIAQKILALYELEGTTVLLTSCSSEALLEAEKQMLSALNYKR 600
EIFQFLQQVNWKEFSKCLFIAQKILALYELEGTTVLLTSCSSEALLEAEKQMLSALNYKR
Sbjct: 541 EIFQFLQQVNWKEFSKCLFIAQKILALYELEGTTVLLTSCSSEALLEAEKQMLSALNYKR 600
Query: 601 IEVENKEVLHGKKWKGLTHNLLKKQNSSPNTVIINELTSETTAEVIITGCVKEVNETYKL 660
IEVENKEVLHGKKWKGLTHNLLKKQNSSPNTVIINELTSETTAEVIITGCVKEVNETYKL
Sbjct: 601 IEVENKEVLHGKKWKGLTHNLLKKQNSSPNTVIINELTSETTAEVIITGCVKEVNETYKL 660
Query: 661 LFNFVEQNMKIERLVEVKPSLVIDYLKTEKKLFWPKIKKVNVQVSFNPENKQKGILLTGS 720
LFNFVEQNMKIERLVEVKPSLVIDYLKTEKKLFWPKIKKVNVQVSFNPENKQKGILLTGS
Sbjct: 661 LFNFVEQNMKIERLVEVKPSLVIDYLKTEKKLFWPKIKKVNVQVSFNPENKQKGILLTGS 720
Query: 721 KTEVLKAVDIVKQVWDSVCVKSVHTDKPGAKQFFQDKARFYQSEIKRLFGCYIELQENEV 780
KTEVLKAVDIVKQVWDSVCVKSVHTDKPGAKQFFQDKARFYQSEIKRLFGCYIELQENEV
Sbjct: 721 KTEVLKAVDIVKQVWDSVCVKSVHTDKPGAKQFFQDKARFYQSEIKRLFGCYIELQENEV 780
Query: 781 MKEGGSPAGQKCFSRTVLAPGVVLIVQQGDLARLPVDVVVNASNEDLKHYGGLAAALSKA 840
MKEGGSPAGQKCFSRTVLAPGVVLIVQQGDLARLPVDVVVNASNEDLKHYGGLAAALSKA
Sbjct: 781 MKEGGSPAGQKCFSRTVLAPGVVLIVQQGDLARLPVDVVVNASNEDLKHYGGLAAALSKA 840
Query: 841 AGPELQADCDQIVKREGRLLPGNATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRA 900
AGPELQADCDQIVKREGRLLPGNATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRA
Sbjct: 841 AGPELQADCDQIVKREGRLLPGNATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRA 900
Query: 901 VQLSLCLAEKYKYRSIAIPAISSGVFGFPLGRCVETIVSAIKENFQFKKDGHCLKEIYLV 960
VQLSLCLAEKYKYRSIAIPAISSGVFGFPLGRCVETIVSAIKENFQFKKDGHCLKEIYLV
Sbjct: 901 VQLSLCLAEKYKYRSIAIPAISSGVFGFPLGRCVETIVSAIKENFQFKKDGHCLKEIYLV 960
Query: 961 DVSEKTVEAFAEAVKTVFKATLPDTAAPPGLPPAAAGPGKTSWEKGSLVSPGGLQMLLVK 1020
DVSEKTVEAFAEAVKTVFKATLPDTAAPPGLPPAAAGPGKTSWEKGSLVSPGGLQMLLVK
Sbjct: 961 DVSEKTVEAFAEAVKTVFKATLPDTAAPPGLPPAAAGPGKTSWEKGSLVSPGGLQMLLVK 1020
Query: 1021 EGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMGTVLKTS 1080
EGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMGTVLKTS
Sbjct: 1021 EGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMGTVLKTS 1080
Query: 1081 SWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITESLSLKSIAFPAIGTGNLGFP 1140
SWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITESLSLKSIAFPAIGTGNLGFP
Sbjct: 1081 SWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITESLSLKSIAFPAIGTGNLGFP 1140
Query: 1141 KNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQAFSDEFARRANGNLVSDKIP 1200
KNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQAFSDEFARRANGNLVSDKIP
Sbjct: 1141 KNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQAFSDEFARRANGNLVSDKIP 1200
Query: 1201 KAKDTQGFYGTVSSPDSGVYEMKIGSIIFQVASGDITKEEADVIVNSTSNSFNLKAGVSK 1260
KAKDTQGFYGTVSSPDSGVYEMKIGSIIFQVASGDITKEEADVIVNSTSNSFNLKAGVSK
Sbjct: 1201 KAKDTQGFYGTVSSPDSGVYEMKIGSIIFQVASGDITKEEADVIVNSTSNSFNLKAGVSK 1260
Query: 1261 AILECAGQNVERECSQQAQQRKNDYIITGGGFLRCKNIIHVIGGNDVKSSVSSVLQECEK 1320
AILECAGQNVERECSQQAQQRKNDYIITGGGFLRCKNIIHVIGGNDVKSSVSSVLQECEK
Sbjct: 1261 AILECAGQNVERECSQQAQQRKNDYIITGGGFLRCKNIIHVIGGNDVKSSVSSVLQECEK 1320
Query: 1321 KNYSSICLPAIGTGNAKQHPDKVAEAIIDAIEDFVQKGSAQSVKKVKVVIFLPQVLDVFY 1380
KNYSSICLPAIGTGNAKQHPDKVAEAIIDAIEDFVQKGSAQSVKKVKVVIFLPQVLDVFY
Sbjct: 1321 KNYSSICLPAIGTGNAKQHPDKVAEAIIDAIEDFVQKGSAQSVKKVKVVIFLPQVLDVFY 1380
Query: 1381 ANMKKREGTQLSSQQSVMSKLASFLGFSKQSPQKKNHLVLEKKTESATFRVCGENVTCVE 1440
ANMKKREGTQLSSQQSVMSKLASFLGFSKQSPQKKNHLVLEKKTESATFRVCGENVTCVE
Sbjct: 1381 ANMKKREGTQLSSQQSVMSKLASFLGFSKQSPQKKNHLVLEKKTESATFRVCGENVTCVE 1440
Query: 1441 YAISWLQDLIEKEQCPYTSEDECIKDFDEKEYQELNELQKKLNINISLDHKRPLIKVLGI 1500
YAISWLQDLIEKEQCPYTSEDECIKDFDEKEYQELNELQKKLNINISLDHKRPLIKVLGI
Sbjct: 1441 YAISWLQDLIEKEQCPYTSEDECIKDFDEKEYQELNELQKKLNINISLDHKRPLIKVLGI 1500
Query: 1501 SRDVMQARDEIEAMIKRVRLAKEQESRADCISEFIEWQYNDNNTSHCFNKMTNLKLEDAR 1560
SRDVMQARDEIEAMIKRVRLAKEQESRADCISEFIEWQYNDNNTSHCFNKMTNLKLEDAR
Sbjct: 1501 SRDVMQARDEIEAMIKRVRLAKEQESRADCISEFIEWQYNDNNTSHCFNKMTNLKLEDAR 1560
Query: 1561 REKKKTVDVKINHRHYTVNLNTYTATDTKGHSLSVQRLTKSKVDIPAHWSDMKQQNFCVV 1620
REKKKTVDVKINHRHYTVNLNTYTATDTKGHSLSVQRLTKSKVDIPAHWSDMKQQNFCVV
Sbjct: 1561 REKKKTVDVKINHRHYTVNLNTYTATDTKGHSLSVQRLTKSKVDIPAHWSDMKQQNFCVV 1620
Query: 1621 ELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQAKKKTMDAKNGQTMNEKQL 1680
ELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQAKKKTMDAKNGQTMNEKQL
Sbjct: 1621 ELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQAKKKTMDAKNGQTMNEKQL 1680
Query: 1681 FHGTDAGSVPHVNRNGFNRSYAGKNAVAYGKGTYFAVNANYSANDTYSRPDANGRKHVYY 1740
FHGTDAGSVPHVNRNGFNRSYAGKNAVAYGKGTYFAVNANYSANDTYSRPDANGRKHVYY
Sbjct: 1681 FHGTDAGSVPHVNRNGFNRSYAGKNAVAYGKGTYFAVNANYSANDTYSRPDANGRKHVYY 1740
Query: 1741 VRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLITFR 1800
VRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLITFR
Sbjct: 1741 VRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLITFR 1800
Query: 1801 K 1801
K
Sbjct: 1801 K 1801
>gi|165377137 poly (ADP-ribose) polymerase family, member 15 isoform 1
[Homo sapiens]
Length = 678
Score = 390 bits (1002), Expect = e-108
Identities = 210/395 (53%), Positives = 275/395 (69%), Gaps = 2/395 (0%)
Query: 1007 SLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVG 1066
S+ + GL + L+ V DV+VNSVP++L L GPLS++ L+KAGP LQ+ELD
Sbjct: 82 SIQTKEGLNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDRR 141
Query: 1067 QGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITESLSLKS 1126
+ +G + TS NLDC+ VLH VAP W NG+ +S +IM +II++C+ E LS S
Sbjct: 142 RETEEKVGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSFSS 201
Query: 1127 IAFPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKT--LQEVHFLLHPSDHENIQAFSD 1184
I FP IGTG+L FPK +FA+LI+SEVF++SS + T LQEVHFL++ +D E QAF D
Sbjct: 202 ITFPMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAFLD 261
Query: 1185 EFARRANGNLVSDKIPKAKDTQGFYGTVSSPDSGVYEMKIGSIIFQVASGDITKEEADVI 1244
EF + N +IP A DTQG GTVS P YEMKIG+I FQVA+GDI E+ DVI
Sbjct: 262 EFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGAITFQVATGDIATEQVDVI 321
Query: 1245 VNSTSNSFNLKAGVSKAILECAGQNVERECSQQAQQRKNDYIITGGGFLRCKNIIHVIGG 1304
VNST+ +FN K+GVS+AILE AGQ VE EC+ A Q D+IIT GG L+CK IIHV GG
Sbjct: 322 VNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFIITPGGCLKCKIIIHVPGG 381
Query: 1305 NDVKSSVSSVLQECEKKNYSSICLPAIGTGNAKQHPDKVAEAIIDAIEDFVQKGSAQSVK 1364
DV+ +V+SVL+ECE++ Y+S+ LPAIGTGNA ++P VA+ IIDAI DF + S S+K
Sbjct: 382 KDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQHSTPSLK 441
Query: 1365 KVKVVIFLPQVLDVFYANMKKREGTQLSSQQSVMS 1399
VKVVIF P++L++FY +MKKR+ + + QS S
Sbjct: 442 TVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFS 476
Score = 283 bits (725), Expect = 8e-76
Identities = 129/196 (65%), Positives = 155/196 (79%)
Query: 1604 DIPAHWSDMKQQNFCVVELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQAK 1663
++P HW+DM Q FC+V+L P EYNT+ KF +TCS + IEKIERIQN LW SYQ K
Sbjct: 481 NLPEHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVK 540
Query: 1664 KKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNGFNRSYAGKNAVAYGKGTYFAVNANYSA 1723
K+ MD KN NE+ LFHGTDA SVP+VN++GFNRS AGKNAV+YGKGTYFAV+A+YSA
Sbjct: 541 KRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSA 600
Query: 1724 NDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPSLF 1783
DTYS+PD+NGRKH+Y VRVLTG++T G L+ PP KNP NPTDL+D+VT+N P LF
Sbjct: 601 KDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLF 660
Query: 1784 VAFYDYQAYPEYLITF 1799
V F+D QAYPEYLITF
Sbjct: 661 VVFFDNQAYPEYLITF 676
Score = 94.0 bits (232), Expect = 1e-18
Identities = 100/398 (25%), Positives = 173/398 (43%), Gaps = 31/398 (7%)
Query: 801 GVVLIVQQGDLARLPVDVVVNASNEDLKHYGG-LAAALSKAAGPELQADCDQIVKREGRL 859
G+ L + GD+ + DV+VN+ +L+ GG L+ A + AGP LQ + D +RE
Sbjct: 88 GLNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDR-RRETEE 146
Query: 860 LPGNATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIP 919
GN ++ L V+HAV P W+ A ++ ++ L E + SI P
Sbjct: 147 KVGNIFMTSGCNLDCKAVLHAVAPYWNN-GAETSWQIMANIIKKCLTTVEVLSFSSITFP 205
Query: 920 AISSGVFGFPLGRCVETIVSAIKE-NFQFKKDGHCLKEIYLVDVS--EKTVEAFAEAVK- 975
I +G FP + I+S + E + + L+E++ + + ++ +AF +
Sbjct: 206 MIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAFLDEFTN 265
Query: 976 ----TVFKATLPDTAAPPGLPPAAAGPGKTSWEKGSLVSPGGLQMLLVKEGVQNAKTDVV 1031
KA +P G+ + P T++E + G + + + + DV+
Sbjct: 266 WSRINPNKARIPMAGDTQGVVGTVSKPCFTAYE----MKIGAITFQVATGDIATEQVDVI 321
Query: 1032 VNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMGTVLKTSSWNLDCRYVLH 1091
VNS G +S+++LE AG ++ E + A + T L C+ ++H
Sbjct: 322 VNSTARTFNRKSG-VSRAILEGAGQAVESECAVL---AAQPHRDFIITPGGCLKCKIIIH 377
Query: 1092 VVAPEWRNGSTSSLKIMEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISE 1151
V G K + ++ EC E S++ PAIGTGN G A+ II
Sbjct: 378 V------PGGKDVRKTVTSVLEEC----EQRKYTSVSLPAIGTGNAGKNPITVADNIIDA 427
Query: 1152 VFKFSSKNQLKTLQEVHFLLHPSDHENIQAFSDEFARR 1189
+ FSS++ +L+ V ++ + NI F D +R
Sbjct: 428 IVDFSSQHSTPSLKTVKVVIFQPELLNI--FYDSMKKR 463
Score = 52.0 bits (123), Expect = 5e-06
Identities = 45/185 (24%), Positives = 84/185 (45%), Gaps = 17/185 (9%)
Query: 792 CFSRTVLAPGVVLI-VQQGDLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCD 850
CF+ + G + V GD+A VDV+VN++ G++ A+ + AG ++++C
Sbjct: 293 CFTAYEMKIGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECA 352
Query: 851 QIVKREGRLLPGNATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEK 910
+ + R + I+ G L +IH G + +R+ V L E+
Sbjct: 353 VLAAQPHR----DFIITPGGCLKCKIIIHVPGGK-----------DVRKTVTSVLEECEQ 397
Query: 911 YKYRSIAIPAISSGVFGFPLGRCVETIVSAIKENFQFKKDGHCLKEIYLVDVSEKTVEAF 970
KY S+++PAI +G G + I+ AI + F + LK + +V + + F
Sbjct: 398 RKYTSVSLPAIGTGNAGKNPITVADNIIDAIVD-FSSQHSTPSLKTVKVVIFQPELLNIF 456
Query: 971 AEAVK 975
+++K
Sbjct: 457 YDSMK 461
>gi|22749259 poly (ADP-ribose) polymerase family, member 15 isoform 2
[Homo sapiens]
Length = 444
Score = 283 bits (725), Expect = 8e-76
Identities = 129/196 (65%), Positives = 155/196 (79%)
Query: 1604 DIPAHWSDMKQQNFCVVELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQAK 1663
++P HW+DM Q FC+V+L P EYNT+ KF +TCS + IEKIERIQN LW SYQ K
Sbjct: 247 NLPEHWTDMNHQLFCMVQLEPGQSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVK 306
Query: 1664 KKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNGFNRSYAGKNAVAYGKGTYFAVNANYSA 1723
K+ MD KN NE+ LFHGTDA SVP+VN++GFNRS AGKNAV+YGKGTYFAV+A+YSA
Sbjct: 307 KRQMDIKNDHKNNERLLFHGTDADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSA 366
Query: 1724 NDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPSLF 1783
DTYS+PD+NGRKH+Y VRVLTG++T G L+ PP KNP NPTDL+D+VT+N P LF
Sbjct: 367 KDTYSKPDSNGRKHMYVVRVLTGVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLF 426
Query: 1784 VAFYDYQAYPEYLITF 1799
V F+D QAYPEYLITF
Sbjct: 427 VVFFDNQAYPEYLITF 442
Score = 233 bits (594), Expect = 1e-60
Identities = 127/233 (54%), Positives = 164/233 (70%)
Query: 1167 VHFLLHPSDHENIQAFSDEFARRANGNLVSDKIPKAKDTQGFYGTVSSPDSGVYEMKIGS 1226
+H ++ S+ QAF DEF + N +IP A DTQG GTVS P YEMKIG+
Sbjct: 10 LHNIVVVSNCFYFQAFLDEFTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGA 69
Query: 1227 IIFQVASGDITKEEADVIVNSTSNSFNLKAGVSKAILECAGQNVERECSQQAQQRKNDYI 1286
I FQVA+GDI E+ DVIVNST+ +FN K+GVS+AILE AGQ VE EC+ A Q D+I
Sbjct: 70 ITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFI 129
Query: 1287 ITGGGFLRCKNIIHVIGGNDVKSSVSSVLQECEKKNYSSICLPAIGTGNAKQHPDKVAEA 1346
IT GG L+CK IIHV GG DV+ +V+SVL+ECE++ Y+S+ LPAIGTGNA ++P VA+
Sbjct: 130 ITPGGCLKCKIIIHVPGGKDVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADN 189
Query: 1347 IIDAIEDFVQKGSAQSVKKVKVVIFLPQVLDVFYANMKKREGTQLSSQQSVMS 1399
IIDAI DF + S S+K VKVVIF P++L++FY +MKKR+ + + QS S
Sbjct: 190 IIDAIVDFSSQHSTPSLKTVKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFS 242
Score = 57.0 bits (136), Expect = 2e-07
Identities = 53/211 (25%), Positives = 90/211 (42%), Gaps = 20/211 (9%)
Query: 979 KATLPDTAAPPGLPPAAAGPGKTSWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLD 1038
KA +P G+ + P T++E + G + + + + DV+VNS
Sbjct: 39 KARIPMAGDTQGVVGTVSKPCFTAYE----MKIGAITFQVATGDIATEQVDVIVNSTART 94
Query: 1039 LVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWR 1098
G +S+++LE AG ++ E + A + T L C+ ++HV
Sbjct: 95 FNRKSG-VSRAILEGAGQAVESECAVLA---AQPHRDFIITPGGCLKCKIIIHVP----- 145
Query: 1099 NGSTSSLKIMEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISEVFKFSSK 1158
G K + ++ EC E S++ PAIGTGN G A+ II + FSS+
Sbjct: 146 -GGKDVRKTVTSVLEEC----EQRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQ 200
Query: 1159 NQLKTLQEVHFLLHPSDHENIQAFSDEFARR 1189
+ +L+ V ++ + NI F D +R
Sbjct: 201 HSTPSLKTVKVVIFQPELLNI--FYDSMKKR 229
Score = 52.0 bits (123), Expect = 5e-06
Identities = 45/185 (24%), Positives = 84/185 (45%), Gaps = 17/185 (9%)
Query: 792 CFSRTVLAPGVVLI-VQQGDLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCD 850
CF+ + G + V GD+A VDV+VN++ G++ A+ + AG ++++C
Sbjct: 59 CFTAYEMKIGAITFQVATGDIATEQVDVIVNSTARTFNRKSGVSRAILEGAGQAVESECA 118
Query: 851 QIVKREGRLLPGNATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEK 910
+ + R + I+ G L +IH G + +R+ V L E+
Sbjct: 119 VLAAQPHR----DFIITPGGCLKCKIIIHVPGGK-----------DVRKTVTSVLEECEQ 163
Query: 911 YKYRSIAIPAISSGVFGFPLGRCVETIVSAIKENFQFKKDGHCLKEIYLVDVSEKTVEAF 970
KY S+++PAI +G G + I+ AI + F + LK + +V + + F
Sbjct: 164 RKYTSVSLPAIGTGNAGKNPITVADNIIDAIVD-FSSQHSTPSLKTVKVVIFQPELLNIF 222
Query: 971 AEAVK 975
+++K
Sbjct: 223 YDSMK 227
>gi|226371718 poly (ADP-ribose) polymerase family, member 9 isoform c
[Homo sapiens]
Length = 710
Score = 224 bits (572), Expect = 4e-58
Identities = 152/430 (35%), Positives = 235/430 (54%), Gaps = 31/430 (7%)
Query: 765 IKRLFGCYIELQENEVMKEGGSPAGQKCFSRTVLAPGVVLIVQQGDLARLPVDVVVNASN 824
++ FGC L ++EG S + Q R +L P + L V + DL VD VVNA+N
Sbjct: 50 LQNKFGCISTLVSP--VQEGNSKSLQ--VFRKMLTPRIELSVWKDDLTTHAVDAVVNAAN 105
Query: 825 EDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATISKAGKLPYHHVIHAVGPR 884
EDL H GGLA AL KA G E+Q + Q V R G++ G ++ AG+LP +IHAVGPR
Sbjct: 106 EDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPR 165
Query: 885 WSGYEAPRCVYLLRRAVQ--LSLCLAEKYKYRSIAIPAISSGVFGFPLGRCVETIVSAIK 942
W ++ C L+RA+ L+ + + +++AIPA+SSG+F FPL C +TIV I+
Sbjct: 166 WMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIR 225
Query: 943 ENFQFKKDGHCLKEIYLVDVSEKTVEAFAEAVKTVF-KATLPDTAAPPGLPPAAAGPGKT 1001
+ Q K LKEI+LV + TV AF A + + K+ L G+
Sbjct: 226 VSLQGKPMMSNLKEIHLVSNEDPTVAAFKAASEFILGKSEL----------------GQE 269
Query: 1002 SWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSV-PLDLVLSRGPLSKSLLEKAGPELQE 1060
+ + + L + +V+ ++ DV+VNSV P D+ + GP++KS+L++AG E++
Sbjct: 270 TTPSFNAMVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITV--GPVAKSILQQAGVEMKS 327
Query: 1061 ELDTVGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITE 1120
E VL T +NL C+Y+ HV+ W + +I++ ++EC+E
Sbjct: 328 EFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---W-HSEFPKPQILKHAMKECLEKCI 383
Query: 1121 SLSLKSIAFPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQ 1180
++ SI+FPA+GTGN+ K AE++ EV F +K+ +K V F++ P+D E +
Sbjct: 384 EQNITSISFPALGTGNMEIKKETAAEILFDEVLTF-AKDHVKHQLTVKFVIFPTDLEIYK 442
Query: 1181 AFSDEFARRA 1190
AFS E A+R+
Sbjct: 443 AFSSEMAKRS 452
Score = 145 bits (367), Expect = 3e-34
Identities = 141/553 (25%), Positives = 260/553 (47%), Gaps = 54/553 (9%)
Query: 993 PAAAGPGKTSWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLE 1052
P G K+ +++P +++ + K+ + D VVN+ DL L G L+ +L++
Sbjct: 63 PVQEGNSKSLQVFRKMLTPR-IELSVWKDDLTTHAVDAVVNAANEDL-LHGGGLALALVK 120
Query: 1053 KAGPELQEELDT-VGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEW----RNGSTSSLKI 1107
G E+QEE V + VS G + T + L C+ ++H V P W + G T L+
Sbjct: 121 AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR 180
Query: 1108 MEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISEV-FKFSSKNQLKTLQE 1166
I + I ++ +K++A PA+ +G FP N+ + I+ + K + L+E
Sbjct: 181 AIVSILNYV-IYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKE 239
Query: 1167 VHFLLHPSDHENIQAFSDEFARRANGNLVSDKIPKAKDTQGFYGTVSSPDSGVYEMKIGS 1226
+H + ++ + AF +A + K ++T + M + +
Sbjct: 240 IHLV--SNEDPTVAAF------KAASEFILGKSELGQETTPSFNA----------MVVNN 281
Query: 1227 IIFQVASGDITKEEADVIVNSTSNSFNLKAG-VSKAILECAGQNVERE---CSQQAQQRK 1282
+ Q+ G I + ADVIVNS N ++ G V+K+IL+ AG ++ E + QR
Sbjct: 282 LTLQIVQGHIEWQTADVIVNSV-NPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRS 340
Query: 1283 NDYIITGGGFLRCKNIIHVIGGND------VKSSVSSVLQECEKKNYSSICLPAIGTGNA 1336
++T G L CK I HV+ ++ +K ++ L++C ++N +SI PA+GTGN
Sbjct: 341 QLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNM 400
Query: 1337 KQHPDKVAEAIIDAIEDFVQKGSAQSVKKVKVVIFLPQVLDVFYANMKKREGTQLSSQQS 1396
+ + AE + D + F K + VK VIF P L+++ A SS+ +
Sbjct: 401 EIKKETAAEILFDEVLTFA-KDHVKHQLTVKFVIF-PTDLEIYKA---------FSSEMA 449
Query: 1397 VMSKLASFLGFSKQSPQKKNHLVLEKKTESATFRVCGENVTCVEYAISWLQDLIEKEQCP 1456
SK+ S +S ++ + S + G NV + A +W+Q ++ Q
Sbjct: 450 KRSKMLSLNNYSVPQSTREEKRENGLEARSPAINLMGFNVEEMYEAHAWIQRILSL-QNH 508
Query: 1457 YTSEDECIKDFDEKEYQELNELQKKLNINIS--LDHKRPLIKVLGISRDVMQARDEIEAM 1514
+ E+ I KE+ L++LQK +++I+ + R +++ G D+++ IE M
Sbjct: 509 HIIENNHILYLGRKEHDILSQLQKTSSVSITEIISPGRTELEIEGARADLIEVVMNIEDM 568
Query: 1515 IKRVR--LAKEQE 1525
+ +V+ +A+++E
Sbjct: 569 LCKVQEEMARKKE 581
>gi|226371716 poly (ADP-ribose) polymerase family, member 9 isoform b
[Homo sapiens]
Length = 819
Score = 224 bits (572), Expect = 4e-58
Identities = 152/430 (35%), Positives = 235/430 (54%), Gaps = 31/430 (7%)
Query: 765 IKRLFGCYIELQENEVMKEGGSPAGQKCFSRTVLAPGVVLIVQQGDLARLPVDVVVNASN 824
++ FGC L ++EG S + Q R +L P + L V + DL VD VVNA+N
Sbjct: 50 LQNKFGCISTLVSP--VQEGNSKSLQ--VFRKMLTPRIELSVWKDDLTTHAVDAVVNAAN 105
Query: 825 EDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATISKAGKLPYHHVIHAVGPR 884
EDL H GGLA AL KA G E+Q + Q V R G++ G ++ AG+LP +IHAVGPR
Sbjct: 106 EDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPR 165
Query: 885 WSGYEAPRCVYLLRRAVQ--LSLCLAEKYKYRSIAIPAISSGVFGFPLGRCVETIVSAIK 942
W ++ C L+RA+ L+ + + +++AIPA+SSG+F FPL C +TIV I+
Sbjct: 166 WMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIR 225
Query: 943 ENFQFKKDGHCLKEIYLVDVSEKTVEAFAEAVKTVF-KATLPDTAAPPGLPPAAAGPGKT 1001
+ Q K LKEI+LV + TV AF A + + K+ L G+
Sbjct: 226 VSLQGKPMMSNLKEIHLVSNEDPTVAAFKAASEFILGKSEL----------------GQE 269
Query: 1002 SWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSV-PLDLVLSRGPLSKSLLEKAGPELQE 1060
+ + + L + +V+ ++ DV+VNSV P D+ + GP++KS+L++AG E++
Sbjct: 270 TTPSFNAMVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITV--GPVAKSILQQAGVEMKS 327
Query: 1061 ELDTVGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITE 1120
E VL T +NL C+Y+ HV+ W + +I++ ++EC+E
Sbjct: 328 EFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---W-HSEFPKPQILKHAMKECLEKCI 383
Query: 1121 SLSLKSIAFPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQ 1180
++ SI+FPA+GTGN+ K AE++ EV F +K+ +K V F++ P+D E +
Sbjct: 384 EQNITSISFPALGTGNMEIKKETAAEILFDEVLTF-AKDHVKHQLTVKFVIFPTDLEIYK 442
Query: 1181 AFSDEFARRA 1190
AFS E A+R+
Sbjct: 443 AFSSEMAKRS 452
Score = 191 bits (485), Expect = 6e-48
Identities = 205/822 (24%), Positives = 351/822 (42%), Gaps = 115/822 (13%)
Query: 993 PAAAGPGKTSWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLE 1052
P G K+ +++P +++ + K+ + D VVN+ DL L G L+ +L++
Sbjct: 63 PVQEGNSKSLQVFRKMLTPR-IELSVWKDDLTTHAVDAVVNAANEDL-LHGGGLALALVK 120
Query: 1053 KAGPELQEELDT-VGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEW----RNGSTSSLKI 1107
G E+QEE V + VS G + T + L C+ ++H V P W + G T L+
Sbjct: 121 AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR 180
Query: 1108 MEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISEV-FKFSSKNQLKTLQE 1166
I + I ++ +K++A PA+ +G FP N+ + I+ + K + L+E
Sbjct: 181 AIVSILNYV-IYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKE 239
Query: 1167 VHFLLHPSDHENIQAFSDEFARRANGNLVSDKIPKAKDTQGFYGTVSSPDSGVYEMKIGS 1226
+H + ++ + AF +A + K ++T + M + +
Sbjct: 240 IHLV--SNEDPTVAAF------KAASEFILGKSELGQETTPSFNA----------MVVNN 281
Query: 1227 IIFQVASGDITKEEADVIVNSTSNSFNLKAG-VSKAILECAGQNVERE---CSQQAQQRK 1282
+ Q+ G I + ADVIVNS N ++ G V+K+IL+ AG ++ E + QR
Sbjct: 282 LTLQIVQGHIEWQTADVIVNSV-NPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRS 340
Query: 1283 NDYIITGGGFLRCKNIIHVIGGND------VKSSVSSVLQECEKKNYSSICLPAIGTGNA 1336
++T G L CK I HV+ ++ +K ++ L++C ++N +SI PA+GTGN
Sbjct: 341 QLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNM 400
Query: 1337 KQHPDKVAEAIIDAIEDFVQKGSAQSVKKVKVVIFLPQVLDVFYANMKKREGTQLSSQQS 1396
+ + AE + D + F K + VK VIF P L+++ A SS+ +
Sbjct: 401 EIKKETAAEILFDEVLTFA-KDHVKHQLTVKFVIF-PTDLEIYKA---------FSSEMA 449
Query: 1397 VMSKLASFLGFSKQSPQKKNHLVLEKKTESATFRVCGENVTCVEYAISWLQDLIEKEQCP 1456
SK+ S +S ++ + S + G NV + A +W+Q ++ +
Sbjct: 450 KRSKMLSLNNYSVPQSTREEKRENGLEARSPAINLMGFNVEEMYEAHAWIQRILSLQN-H 508
Query: 1457 YTSEDECIKDFDEKEYQELNELQKKLNINISLDHKRPLIKVLGISRDVMQARDEIEAMIK 1516
+ E+ I KE+ L++LQK +++I+ + R E+E
Sbjct: 509 HIIENNHILYLGRKEHDILSQLQKTSSVSIT--------------EIISPGRTELEI--- 551
Query: 1517 RVRLAKEQESRADCISEFIEWQYNDNNTSHCFNKMTNLKLEDARREKKKTVDVKINHRHY 1576
+ +RAD I + + + + ++ E AR+++ R
Sbjct: 552 -------EGARADLIEVVMNIE----------DMLCKVQEEMARKKE----------RGL 584
Query: 1577 TVNLNTYTATDTKGHSLSVQRLTKSKVDIPAHWSDMKQQNFCVVELLPSDPEYNTVASKF 1636
+L +T K + + K +P ELL ++
Sbjct: 585 WRSLGQWTIQQQKTQDEMKENIIFLKCPVPP-----------TQELLDQKKQF------- 626
Query: 1637 NQTCSHFRIEKIERIQNPDLWNSYQAKKKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNG 1696
+ C ++ K+E+I N L ++Q KKK M+ K + +LF V R G
Sbjct: 627 -EKCG-LQVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVG 684
Query: 1697 FNRSYAGKNAVAYGKGTYFAVNANYSANDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLI 1756
F R Y+ YG G YF N A A+ +V+ VLTG + G+ I
Sbjct: 685 FQRMYSTPCDPKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNI 744
Query: 1757 VPPSKNPQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLIT 1798
VPP +P D +D+V DNV P FV F QA P+YL T
Sbjct: 745 VPPPLSP-GAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWT 785
>gi|226371714 poly (ADP-ribose) polymerase family, member 9 isoform b
[Homo sapiens]
Length = 819
Score = 224 bits (572), Expect = 4e-58
Identities = 152/430 (35%), Positives = 235/430 (54%), Gaps = 31/430 (7%)
Query: 765 IKRLFGCYIELQENEVMKEGGSPAGQKCFSRTVLAPGVVLIVQQGDLARLPVDVVVNASN 824
++ FGC L ++EG S + Q R +L P + L V + DL VD VVNA+N
Sbjct: 50 LQNKFGCISTLVSP--VQEGNSKSLQ--VFRKMLTPRIELSVWKDDLTTHAVDAVVNAAN 105
Query: 825 EDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATISKAGKLPYHHVIHAVGPR 884
EDL H GGLA AL KA G E+Q + Q V R G++ G ++ AG+LP +IHAVGPR
Sbjct: 106 EDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPR 165
Query: 885 WSGYEAPRCVYLLRRAVQ--LSLCLAEKYKYRSIAIPAISSGVFGFPLGRCVETIVSAIK 942
W ++ C L+RA+ L+ + + +++AIPA+SSG+F FPL C +TIV I+
Sbjct: 166 WMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIR 225
Query: 943 ENFQFKKDGHCLKEIYLVDVSEKTVEAFAEAVKTVF-KATLPDTAAPPGLPPAAAGPGKT 1001
+ Q K LKEI+LV + TV AF A + + K+ L G+
Sbjct: 226 VSLQGKPMMSNLKEIHLVSNEDPTVAAFKAASEFILGKSEL----------------GQE 269
Query: 1002 SWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSV-PLDLVLSRGPLSKSLLEKAGPELQE 1060
+ + + L + +V+ ++ DV+VNSV P D+ + GP++KS+L++AG E++
Sbjct: 270 TTPSFNAMVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITV--GPVAKSILQQAGVEMKS 327
Query: 1061 ELDTVGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITE 1120
E VL T +NL C+Y+ HV+ W + +I++ ++EC+E
Sbjct: 328 EFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---W-HSEFPKPQILKHAMKECLEKCI 383
Query: 1121 SLSLKSIAFPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQ 1180
++ SI+FPA+GTGN+ K AE++ EV F +K+ +K V F++ P+D E +
Sbjct: 384 EQNITSISFPALGTGNMEIKKETAAEILFDEVLTF-AKDHVKHQLTVKFVIFPTDLEIYK 442
Query: 1181 AFSDEFARRA 1190
AFS E A+R+
Sbjct: 443 AFSSEMAKRS 452
Score = 191 bits (485), Expect = 6e-48
Identities = 205/822 (24%), Positives = 351/822 (42%), Gaps = 115/822 (13%)
Query: 993 PAAAGPGKTSWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLE 1052
P G K+ +++P +++ + K+ + D VVN+ DL L G L+ +L++
Sbjct: 63 PVQEGNSKSLQVFRKMLTPR-IELSVWKDDLTTHAVDAVVNAANEDL-LHGGGLALALVK 120
Query: 1053 KAGPELQEELDT-VGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEW----RNGSTSSLKI 1107
G E+QEE V + VS G + T + L C+ ++H V P W + G T L+
Sbjct: 121 AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR 180
Query: 1108 MEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISEV-FKFSSKNQLKTLQE 1166
I + I ++ +K++A PA+ +G FP N+ + I+ + K + L+E
Sbjct: 181 AIVSILNYV-IYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKE 239
Query: 1167 VHFLLHPSDHENIQAFSDEFARRANGNLVSDKIPKAKDTQGFYGTVSSPDSGVYEMKIGS 1226
+H + ++ + AF +A + K ++T + M + +
Sbjct: 240 IHLV--SNEDPTVAAF------KAASEFILGKSELGQETTPSFNA----------MVVNN 281
Query: 1227 IIFQVASGDITKEEADVIVNSTSNSFNLKAG-VSKAILECAGQNVERE---CSQQAQQRK 1282
+ Q+ G I + ADVIVNS N ++ G V+K+IL+ AG ++ E + QR
Sbjct: 282 LTLQIVQGHIEWQTADVIVNSV-NPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRS 340
Query: 1283 NDYIITGGGFLRCKNIIHVIGGND------VKSSVSSVLQECEKKNYSSICLPAIGTGNA 1336
++T G L CK I HV+ ++ +K ++ L++C ++N +SI PA+GTGN
Sbjct: 341 QLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNM 400
Query: 1337 KQHPDKVAEAIIDAIEDFVQKGSAQSVKKVKVVIFLPQVLDVFYANMKKREGTQLSSQQS 1396
+ + AE + D + F K + VK VIF P L+++ A SS+ +
Sbjct: 401 EIKKETAAEILFDEVLTFA-KDHVKHQLTVKFVIF-PTDLEIYKA---------FSSEMA 449
Query: 1397 VMSKLASFLGFSKQSPQKKNHLVLEKKTESATFRVCGENVTCVEYAISWLQDLIEKEQCP 1456
SK+ S +S ++ + S + G NV + A +W+Q ++ +
Sbjct: 450 KRSKMLSLNNYSVPQSTREEKRENGLEARSPAINLMGFNVEEMYEAHAWIQRILSLQN-H 508
Query: 1457 YTSEDECIKDFDEKEYQELNELQKKLNINISLDHKRPLIKVLGISRDVMQARDEIEAMIK 1516
+ E+ I KE+ L++LQK +++I+ + R E+E
Sbjct: 509 HIIENNHILYLGRKEHDILSQLQKTSSVSIT--------------EIISPGRTELEI--- 551
Query: 1517 RVRLAKEQESRADCISEFIEWQYNDNNTSHCFNKMTNLKLEDARREKKKTVDVKINHRHY 1576
+ +RAD I + + + + ++ E AR+++ R
Sbjct: 552 -------EGARADLIEVVMNIE----------DMLCKVQEEMARKKE----------RGL 584
Query: 1577 TVNLNTYTATDTKGHSLSVQRLTKSKVDIPAHWSDMKQQNFCVVELLPSDPEYNTVASKF 1636
+L +T K + + K +P ELL ++
Sbjct: 585 WRSLGQWTIQQQKTQDEMKENIIFLKCPVPP-----------TQELLDQKKQF------- 626
Query: 1637 NQTCSHFRIEKIERIQNPDLWNSYQAKKKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNG 1696
+ C ++ K+E+I N L ++Q KKK M+ K + +LF V R G
Sbjct: 627 -EKCG-LQVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVG 684
Query: 1697 FNRSYAGKNAVAYGKGTYFAVNANYSANDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLI 1756
F R Y+ YG G YF N A A+ +V+ VLTG + G+ I
Sbjct: 685 FQRMYSTPCDPKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNI 744
Query: 1757 VPPSKNPQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLIT 1798
VPP +P D +D+V DNV P FV F QA P+YL T
Sbjct: 745 VPPPLSP-GAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWT 785
>gi|226371712 poly (ADP-ribose) polymerase family, member 9 isoform b
[Homo sapiens]
Length = 819
Score = 224 bits (572), Expect = 4e-58
Identities = 152/430 (35%), Positives = 235/430 (54%), Gaps = 31/430 (7%)
Query: 765 IKRLFGCYIELQENEVMKEGGSPAGQKCFSRTVLAPGVVLIVQQGDLARLPVDVVVNASN 824
++ FGC L ++EG S + Q R +L P + L V + DL VD VVNA+N
Sbjct: 50 LQNKFGCISTLVSP--VQEGNSKSLQ--VFRKMLTPRIELSVWKDDLTTHAVDAVVNAAN 105
Query: 825 EDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATISKAGKLPYHHVIHAVGPR 884
EDL H GGLA AL KA G E+Q + Q V R G++ G ++ AG+LP +IHAVGPR
Sbjct: 106 EDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPR 165
Query: 885 WSGYEAPRCVYLLRRAVQ--LSLCLAEKYKYRSIAIPAISSGVFGFPLGRCVETIVSAIK 942
W ++ C L+RA+ L+ + + +++AIPA+SSG+F FPL C +TIV I+
Sbjct: 166 WMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIR 225
Query: 943 ENFQFKKDGHCLKEIYLVDVSEKTVEAFAEAVKTVF-KATLPDTAAPPGLPPAAAGPGKT 1001
+ Q K LKEI+LV + TV AF A + + K+ L G+
Sbjct: 226 VSLQGKPMMSNLKEIHLVSNEDPTVAAFKAASEFILGKSEL----------------GQE 269
Query: 1002 SWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSV-PLDLVLSRGPLSKSLLEKAGPELQE 1060
+ + + L + +V+ ++ DV+VNSV P D+ + GP++KS+L++AG E++
Sbjct: 270 TTPSFNAMVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITV--GPVAKSILQQAGVEMKS 327
Query: 1061 ELDTVGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITE 1120
E VL T +NL C+Y+ HV+ W + +I++ ++EC+E
Sbjct: 328 EFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---W-HSEFPKPQILKHAMKECLEKCI 383
Query: 1121 SLSLKSIAFPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQ 1180
++ SI+FPA+GTGN+ K AE++ EV F +K+ +K V F++ P+D E +
Sbjct: 384 EQNITSISFPALGTGNMEIKKETAAEILFDEVLTF-AKDHVKHQLTVKFVIFPTDLEIYK 442
Query: 1181 AFSDEFARRA 1190
AFS E A+R+
Sbjct: 443 AFSSEMAKRS 452
Score = 191 bits (485), Expect = 6e-48
Identities = 205/822 (24%), Positives = 351/822 (42%), Gaps = 115/822 (13%)
Query: 993 PAAAGPGKTSWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLE 1052
P G K+ +++P +++ + K+ + D VVN+ DL L G L+ +L++
Sbjct: 63 PVQEGNSKSLQVFRKMLTPR-IELSVWKDDLTTHAVDAVVNAANEDL-LHGGGLALALVK 120
Query: 1053 KAGPELQEELDT-VGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEW----RNGSTSSLKI 1107
G E+QEE V + VS G + T + L C+ ++H V P W + G T L+
Sbjct: 121 AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR 180
Query: 1108 MEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISEV-FKFSSKNQLKTLQE 1166
I + I ++ +K++A PA+ +G FP N+ + I+ + K + L+E
Sbjct: 181 AIVSILNYV-IYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKE 239
Query: 1167 VHFLLHPSDHENIQAFSDEFARRANGNLVSDKIPKAKDTQGFYGTVSSPDSGVYEMKIGS 1226
+H + ++ + AF +A + K ++T + M + +
Sbjct: 240 IHLV--SNEDPTVAAF------KAASEFILGKSELGQETTPSFNA----------MVVNN 281
Query: 1227 IIFQVASGDITKEEADVIVNSTSNSFNLKAG-VSKAILECAGQNVERE---CSQQAQQRK 1282
+ Q+ G I + ADVIVNS N ++ G V+K+IL+ AG ++ E + QR
Sbjct: 282 LTLQIVQGHIEWQTADVIVNSV-NPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRS 340
Query: 1283 NDYIITGGGFLRCKNIIHVIGGND------VKSSVSSVLQECEKKNYSSICLPAIGTGNA 1336
++T G L CK I HV+ ++ +K ++ L++C ++N +SI PA+GTGN
Sbjct: 341 QLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNM 400
Query: 1337 KQHPDKVAEAIIDAIEDFVQKGSAQSVKKVKVVIFLPQVLDVFYANMKKREGTQLSSQQS 1396
+ + AE + D + F K + VK VIF P L+++ A SS+ +
Sbjct: 401 EIKKETAAEILFDEVLTFA-KDHVKHQLTVKFVIF-PTDLEIYKA---------FSSEMA 449
Query: 1397 VMSKLASFLGFSKQSPQKKNHLVLEKKTESATFRVCGENVTCVEYAISWLQDLIEKEQCP 1456
SK+ S +S ++ + S + G NV + A +W+Q ++ +
Sbjct: 450 KRSKMLSLNNYSVPQSTREEKRENGLEARSPAINLMGFNVEEMYEAHAWIQRILSLQN-H 508
Query: 1457 YTSEDECIKDFDEKEYQELNELQKKLNINISLDHKRPLIKVLGISRDVMQARDEIEAMIK 1516
+ E+ I KE+ L++LQK +++I+ + R E+E
Sbjct: 509 HIIENNHILYLGRKEHDILSQLQKTSSVSIT--------------EIISPGRTELEI--- 551
Query: 1517 RVRLAKEQESRADCISEFIEWQYNDNNTSHCFNKMTNLKLEDARREKKKTVDVKINHRHY 1576
+ +RAD I + + + + ++ E AR+++ R
Sbjct: 552 -------EGARADLIEVVMNIE----------DMLCKVQEEMARKKE----------RGL 584
Query: 1577 TVNLNTYTATDTKGHSLSVQRLTKSKVDIPAHWSDMKQQNFCVVELLPSDPEYNTVASKF 1636
+L +T K + + K +P ELL ++
Sbjct: 585 WRSLGQWTIQQQKTQDEMKENIIFLKCPVPP-----------TQELLDQKKQF------- 626
Query: 1637 NQTCSHFRIEKIERIQNPDLWNSYQAKKKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNG 1696
+ C ++ K+E+I N L ++Q KKK M+ K + +LF V R G
Sbjct: 627 -EKCG-LQVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVG 684
Query: 1697 FNRSYAGKNAVAYGKGTYFAVNANYSANDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLI 1756
F R Y+ YG G YF N A A+ +V+ VLTG + G+ I
Sbjct: 685 FQRMYSTPCDPKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNI 744
Query: 1757 VPPSKNPQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLIT 1798
VPP +P D +D+V DNV P FV F QA P+YL T
Sbjct: 745 VPPPLSP-GAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWT 785
>gi|226371710 poly (ADP-ribose) polymerase family, member 9 isoform a
[Homo sapiens]
Length = 854
Score = 224 bits (572), Expect = 4e-58
Identities = 152/430 (35%), Positives = 235/430 (54%), Gaps = 31/430 (7%)
Query: 765 IKRLFGCYIELQENEVMKEGGSPAGQKCFSRTVLAPGVVLIVQQGDLARLPVDVVVNASN 824
++ FGC L ++EG S + Q R +L P + L V + DL VD VVNA+N
Sbjct: 85 LQNKFGCISTLVSP--VQEGNSKSLQ--VFRKMLTPRIELSVWKDDLTTHAVDAVVNAAN 140
Query: 825 EDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATISKAGKLPYHHVIHAVGPR 884
EDL H GGLA AL KA G E+Q + Q V R G++ G ++ AG+LP +IHAVGPR
Sbjct: 141 EDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPR 200
Query: 885 WSGYEAPRCVYLLRRAVQ--LSLCLAEKYKYRSIAIPAISSGVFGFPLGRCVETIVSAIK 942
W ++ C L+RA+ L+ + + +++AIPA+SSG+F FPL C +TIV I+
Sbjct: 201 WMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIR 260
Query: 943 ENFQFKKDGHCLKEIYLVDVSEKTVEAFAEAVKTVF-KATLPDTAAPPGLPPAAAGPGKT 1001
+ Q K LKEI+LV + TV AF A + + K+ L G+
Sbjct: 261 VSLQGKPMMSNLKEIHLVSNEDPTVAAFKAASEFILGKSEL----------------GQE 304
Query: 1002 SWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSV-PLDLVLSRGPLSKSLLEKAGPELQE 1060
+ + + L + +V+ ++ DV+VNSV P D+ + GP++KS+L++AG E++
Sbjct: 305 TTPSFNAMVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITV--GPVAKSILQQAGVEMKS 362
Query: 1061 ELDTVGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITE 1120
E VL T +NL C+Y+ HV+ W + +I++ ++EC+E
Sbjct: 363 EFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---W-HSEFPKPQILKHAMKECLEKCI 418
Query: 1121 SLSLKSIAFPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQ 1180
++ SI+FPA+GTGN+ K AE++ EV F +K+ +K V F++ P+D E +
Sbjct: 419 EQNITSISFPALGTGNMEIKKETAAEILFDEVLTF-AKDHVKHQLTVKFVIFPTDLEIYK 477
Query: 1181 AFSDEFARRA 1190
AFS E A+R+
Sbjct: 478 AFSSEMAKRS 487
Score = 191 bits (485), Expect = 6e-48
Identities = 205/822 (24%), Positives = 351/822 (42%), Gaps = 115/822 (13%)
Query: 993 PAAAGPGKTSWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLE 1052
P G K+ +++P +++ + K+ + D VVN+ DL L G L+ +L++
Sbjct: 98 PVQEGNSKSLQVFRKMLTPR-IELSVWKDDLTTHAVDAVVNAANEDL-LHGGGLALALVK 155
Query: 1053 KAGPELQEELDT-VGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEW----RNGSTSSLKI 1107
G E+QEE V + VS G + T + L C+ ++H V P W + G T L+
Sbjct: 156 AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR 215
Query: 1108 MEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISEV-FKFSSKNQLKTLQE 1166
I + I ++ +K++A PA+ +G FP N+ + I+ + K + L+E
Sbjct: 216 AIVSILNYV-IYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKE 274
Query: 1167 VHFLLHPSDHENIQAFSDEFARRANGNLVSDKIPKAKDTQGFYGTVSSPDSGVYEMKIGS 1226
+H + ++ + AF +A + K ++T + M + +
Sbjct: 275 IHLV--SNEDPTVAAF------KAASEFILGKSELGQETTPSFNA----------MVVNN 316
Query: 1227 IIFQVASGDITKEEADVIVNSTSNSFNLKAG-VSKAILECAGQNVERE---CSQQAQQRK 1282
+ Q+ G I + ADVIVNS N ++ G V+K+IL+ AG ++ E + QR
Sbjct: 317 LTLQIVQGHIEWQTADVIVNSV-NPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRS 375
Query: 1283 NDYIITGGGFLRCKNIIHVIGGND------VKSSVSSVLQECEKKNYSSICLPAIGTGNA 1336
++T G L CK I HV+ ++ +K ++ L++C ++N +SI PA+GTGN
Sbjct: 376 QLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNM 435
Query: 1337 KQHPDKVAEAIIDAIEDFVQKGSAQSVKKVKVVIFLPQVLDVFYANMKKREGTQLSSQQS 1396
+ + AE + D + F K + VK VIF P L+++ A SS+ +
Sbjct: 436 EIKKETAAEILFDEVLTFA-KDHVKHQLTVKFVIF-PTDLEIYKA---------FSSEMA 484
Query: 1397 VMSKLASFLGFSKQSPQKKNHLVLEKKTESATFRVCGENVTCVEYAISWLQDLIEKEQCP 1456
SK+ S +S ++ + S + G NV + A +W+Q ++ +
Sbjct: 485 KRSKMLSLNNYSVPQSTREEKRENGLEARSPAINLMGFNVEEMYEAHAWIQRILSLQN-H 543
Query: 1457 YTSEDECIKDFDEKEYQELNELQKKLNINISLDHKRPLIKVLGISRDVMQARDEIEAMIK 1516
+ E+ I KE+ L++LQK +++I+ + R E+E
Sbjct: 544 HIIENNHILYLGRKEHDILSQLQKTSSVSIT--------------EIISPGRTELEI--- 586
Query: 1517 RVRLAKEQESRADCISEFIEWQYNDNNTSHCFNKMTNLKLEDARREKKKTVDVKINHRHY 1576
+ +RAD I + + + + ++ E AR+++ R
Sbjct: 587 -------EGARADLIEVVMNIE----------DMLCKVQEEMARKKE----------RGL 619
Query: 1577 TVNLNTYTATDTKGHSLSVQRLTKSKVDIPAHWSDMKQQNFCVVELLPSDPEYNTVASKF 1636
+L +T K + + K +P ELL ++
Sbjct: 620 WRSLGQWTIQQQKTQDEMKENIIFLKCPVPP-----------TQELLDQKKQF------- 661
Query: 1637 NQTCSHFRIEKIERIQNPDLWNSYQAKKKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNG 1696
+ C ++ K+E+I N L ++Q KKK M+ K + +LF V R G
Sbjct: 662 -EKCG-LQVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVG 719
Query: 1697 FNRSYAGKNAVAYGKGTYFAVNANYSANDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLI 1756
F R Y+ YG G YF N A A+ +V+ VLTG + G+ I
Sbjct: 720 FQRMYSTPCDPKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNI 779
Query: 1757 VPPSKNPQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLIT 1798
VPP +P D +D+V DNV P FV F QA P+YL T
Sbjct: 780 VPPPLSP-GAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWT 820
>gi|226371706 poly (ADP-ribose) polymerase family, member 9 isoform a
[Homo sapiens]
Length = 854
Score = 224 bits (572), Expect = 4e-58
Identities = 152/430 (35%), Positives = 235/430 (54%), Gaps = 31/430 (7%)
Query: 765 IKRLFGCYIELQENEVMKEGGSPAGQKCFSRTVLAPGVVLIVQQGDLARLPVDVVVNASN 824
++ FGC L ++EG S + Q R +L P + L V + DL VD VVNA+N
Sbjct: 85 LQNKFGCISTLVSP--VQEGNSKSLQ--VFRKMLTPRIELSVWKDDLTTHAVDAVVNAAN 140
Query: 825 EDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATISKAGKLPYHHVIHAVGPR 884
EDL H GGLA AL KA G E+Q + Q V R G++ G ++ AG+LP +IHAVGPR
Sbjct: 141 EDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPR 200
Query: 885 WSGYEAPRCVYLLRRAVQ--LSLCLAEKYKYRSIAIPAISSGVFGFPLGRCVETIVSAIK 942
W ++ C L+RA+ L+ + + +++AIPA+SSG+F FPL C +TIV I+
Sbjct: 201 WMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIR 260
Query: 943 ENFQFKKDGHCLKEIYLVDVSEKTVEAFAEAVKTVF-KATLPDTAAPPGLPPAAAGPGKT 1001
+ Q K LKEI+LV + TV AF A + + K+ L G+
Sbjct: 261 VSLQGKPMMSNLKEIHLVSNEDPTVAAFKAASEFILGKSEL----------------GQE 304
Query: 1002 SWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSV-PLDLVLSRGPLSKSLLEKAGPELQE 1060
+ + + L + +V+ ++ DV+VNSV P D+ + GP++KS+L++AG E++
Sbjct: 305 TTPSFNAMVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITV--GPVAKSILQQAGVEMKS 362
Query: 1061 ELDTVGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITE 1120
E VL T +NL C+Y+ HV+ W + +I++ ++EC+E
Sbjct: 363 EFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVL---W-HSEFPKPQILKHAMKECLEKCI 418
Query: 1121 SLSLKSIAFPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQ 1180
++ SI+FPA+GTGN+ K AE++ EV F +K+ +K V F++ P+D E +
Sbjct: 419 EQNITSISFPALGTGNMEIKKETAAEILFDEVLTF-AKDHVKHQLTVKFVIFPTDLEIYK 477
Query: 1181 AFSDEFARRA 1190
AFS E A+R+
Sbjct: 478 AFSSEMAKRS 487
Score = 191 bits (485), Expect = 6e-48
Identities = 205/822 (24%), Positives = 351/822 (42%), Gaps = 115/822 (13%)
Query: 993 PAAAGPGKTSWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLE 1052
P G K+ +++P +++ + K+ + D VVN+ DL L G L+ +L++
Sbjct: 98 PVQEGNSKSLQVFRKMLTPR-IELSVWKDDLTTHAVDAVVNAANEDL-LHGGGLALALVK 155
Query: 1053 KAGPELQEELDT-VGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEW----RNGSTSSLKI 1107
G E+QEE V + VS G + T + L C+ ++H V P W + G T L+
Sbjct: 156 AGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQR 215
Query: 1108 MEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISEV-FKFSSKNQLKTLQE 1166
I + I ++ +K++A PA+ +G FP N+ + I+ + K + L+E
Sbjct: 216 AIVSILNYV-IYKNTHIKTVAIPALSSGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKE 274
Query: 1167 VHFLLHPSDHENIQAFSDEFARRANGNLVSDKIPKAKDTQGFYGTVSSPDSGVYEMKIGS 1226
+H + ++ + AF +A + K ++T + M + +
Sbjct: 275 IHLV--SNEDPTVAAF------KAASEFILGKSELGQETTPSFNA----------MVVNN 316
Query: 1227 IIFQVASGDITKEEADVIVNSTSNSFNLKAG-VSKAILECAGQNVERE---CSQQAQQRK 1282
+ Q+ G I + ADVIVNS N ++ G V+K+IL+ AG ++ E + QR
Sbjct: 317 LTLQIVQGHIEWQTADVIVNSV-NPHDITVGPVAKSILQQAGVEMKSEFLATKAKQFQRS 375
Query: 1283 NDYIITGGGFLRCKNIIHVIGGND------VKSSVSSVLQECEKKNYSSICLPAIGTGNA 1336
++T G L CK I HV+ ++ +K ++ L++C ++N +SI PA+GTGN
Sbjct: 376 QLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCIEQNITSISFPALGTGNM 435
Query: 1337 KQHPDKVAEAIIDAIEDFVQKGSAQSVKKVKVVIFLPQVLDVFYANMKKREGTQLSSQQS 1396
+ + AE + D + F K + VK VIF P L+++ A SS+ +
Sbjct: 436 EIKKETAAEILFDEVLTFA-KDHVKHQLTVKFVIF-PTDLEIYKA---------FSSEMA 484
Query: 1397 VMSKLASFLGFSKQSPQKKNHLVLEKKTESATFRVCGENVTCVEYAISWLQDLIEKEQCP 1456
SK+ S +S ++ + S + G NV + A +W+Q ++ +
Sbjct: 485 KRSKMLSLNNYSVPQSTREEKRENGLEARSPAINLMGFNVEEMYEAHAWIQRILSLQN-H 543
Query: 1457 YTSEDECIKDFDEKEYQELNELQKKLNINISLDHKRPLIKVLGISRDVMQARDEIEAMIK 1516
+ E+ I KE+ L++LQK +++I+ + R E+E
Sbjct: 544 HIIENNHILYLGRKEHDILSQLQKTSSVSIT--------------EIISPGRTELEI--- 586
Query: 1517 RVRLAKEQESRADCISEFIEWQYNDNNTSHCFNKMTNLKLEDARREKKKTVDVKINHRHY 1576
+ +RAD I + + + + ++ E AR+++ R
Sbjct: 587 -------EGARADLIEVVMNIE----------DMLCKVQEEMARKKE----------RGL 619
Query: 1577 TVNLNTYTATDTKGHSLSVQRLTKSKVDIPAHWSDMKQQNFCVVELLPSDPEYNTVASKF 1636
+L +T K + + K +P ELL ++
Sbjct: 620 WRSLGQWTIQQQKTQDEMKENIIFLKCPVPP-----------TQELLDQKKQF------- 661
Query: 1637 NQTCSHFRIEKIERIQNPDLWNSYQAKKKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNG 1696
+ C ++ K+E+I N L ++Q KKK M+ K + +LF V R G
Sbjct: 662 -EKCG-LQVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVG 719
Query: 1697 FNRSYAGKNAVAYGKGTYFAVNANYSANDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLI 1756
F R Y+ YG G YF N A A+ +V+ VLTG + G+ I
Sbjct: 720 FQRMYSTPCDPKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNI 779
Query: 1757 VPPSKNPQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLIT 1798
VPP +P D +D+V DNV P FV F QA P+YL T
Sbjct: 780 VPPPLSP-GAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWT 820
>gi|157738665 poly (ADP-ribose) polymerase family, member 10 [Homo
sapiens]
Length = 1025
Score = 133 bits (334), Expect = 2e-30
Identities = 70/175 (40%), Positives = 100/175 (57%), Gaps = 4/175 (2%)
Query: 1628 EYNTVASKFNQTC----SHFRIEKIERIQNPDLWNSYQAKKKTMDAKNGQTMNEKQLFHG 1683
E+ V F T S R+ ++ER+ +P L Y+ ++ + + + E+ L+HG
Sbjct: 829 EFQEVVRAFYDTLDAARSSIRVVRVERVSHPLLQQQYELYRERLLQRCERRPVEQVLYHG 888
Query: 1684 TDAGSVPHVNRNGFNRSYAGKNAVAYGKGTYFAVNANYSANDTYSRPDANGRKHVYYVRV 1743
T A +VP + +GFNRS+ G+NA YGKG YFA A+ S D YS P+A+G K V+ RV
Sbjct: 889 TTAPAVPDICAHGFNRSFCGRNATVYGKGVYFARRASLSVQDRYSPPNADGHKAVFVARV 948
Query: 1744 LTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLIT 1798
LTG Y G L PP + P + YD+ D + PS+FV F+D QA P +LIT
Sbjct: 949 LTGDYGQGRRGLRAPPLRGPGHVLLRYDSAVDCICQPSIFVIFHDTQALPTHLIT 1003
>gi|38524594 TCDD-inducible poly(ADP-ribose) polymerase [Homo sapiens]
Length = 657
Score = 131 bits (329), Expect = 7e-30
Identities = 75/203 (36%), Positives = 114/203 (56%), Gaps = 9/203 (4%)
Query: 1606 PAHWSDMK-QQNFCVVELLPSDPEYNTVASKFNQTCSHF--RIEKIERIQNPDLWNSYQA 1662
P W M Q+F V + D Y + + F++T F RI +I R+QN LW Y+
Sbjct: 450 PETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKR 509
Query: 1663 KKKTMDAK---NGQTMNEKQLFHGTDAGSVPHVNRNGFNRSYAGKNAVAYGKGTYFAVNA 1719
KK+ M+ K + +NE+ LFHGT V + ++ F+ GK+A +G+G+YFA A
Sbjct: 510 KKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKA 569
Query: 1720 NYSANDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPT-DLYDTVTDNVH 1778
+YS N +S+ + G ++ +VLTG YT G+H + PP NP + T DLYD+ DN
Sbjct: 570 SYSHN--FSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFF 627
Query: 1779 HPSLFVAFYDYQAYPEYLITFRK 1801
P +FV F D Q+YP ++I + +
Sbjct: 628 EPQIFVIFNDDQSYPYFVIQYEE 650
>gi|12232413 poly ADP-ribose polymerase 12 [Homo sapiens]
Length = 701
Score = 128 bits (322), Expect = 4e-29
Identities = 75/198 (37%), Positives = 112/198 (56%), Gaps = 7/198 (3%)
Query: 1605 IPAHW--SDMKQQNFCVVELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQA 1662
IP +W S + F + L S EY V + FN+T + ++KIER+QN LW YQ
Sbjct: 484 IPDYWDSSALPDPGFQKITLSSSSEEYQKVWNLFNRTLPFYFVQKIERVQNLALWEVYQW 543
Query: 1663 KKKTMDAKNG-QTMNEKQLFHGTDAGSVPHVNRNGFNRSYAGKNAVAYGKGTYFAVNANY 1721
+K M +NG + ++E+QLFHGT A V + + F+ G + +YGKG+YFA +A Y
Sbjct: 544 QKGQMQKQNGGKAVDERQLFHGTSAIFVDAICQQNFDWRVCGVHGTSYGKGSYFARDAAY 603
Query: 1722 SANDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPS 1781
S + YS+ D ++ RVL G + GN S + PP+K + YD+ ++V PS
Sbjct: 604 SHH--YSKSDTQTHT-MFLARVLVGEFVRGNASFVRPPAKEGWS-NAFYDSCVNSVSDPS 659
Query: 1782 LFVAFYDYQAYPEYLITF 1799
+FV F +Q YPEY+I +
Sbjct: 660 IFVIFEKHQVYPEYVIQY 677
>gi|194328777 poly (ADP-ribose) polymerase family, member 11 [Homo
sapiens]
Length = 338
Score = 117 bits (293), Expect = 1e-25
Identities = 74/216 (34%), Positives = 110/216 (50%), Gaps = 20/216 (9%)
Query: 1603 VDIPAHWSDMKQQ-NFCVVELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQ 1661
+ +P HW ++ Q + ++ L EYN VA+ F +T RI++I+RIQN DLW +
Sbjct: 123 IPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFC 182
Query: 1662 AKKKTMDAKNG-QTMNEKQLFHGTDAGSVPHVNRNGFNRSYAGKNAVAYGKGTYFAVNAN 1720
KK + K G +NE+ LFHGT + V + + F+ G + +GKGTYFA +A
Sbjct: 183 RKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARDAA 242
Query: 1721 YSAN-----------------DTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNP 1763
YS+ R K ++ RVL G Y +G+ + PPSK+
Sbjct: 243 YSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSKD- 301
Query: 1764 QNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLITF 1799
+ +LYD+ D+ +P +FV F Q YPEYLI F
Sbjct: 302 GSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDF 337
>gi|27477136 zinc finger antiviral protein isoform 1 [Homo sapiens]
Length = 902
Score = 84.7 bits (208), Expect = 7e-16
Identities = 60/194 (30%), Positives = 93/194 (47%), Gaps = 25/194 (12%)
Query: 1614 QQNFCVV--------ELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQAKKK 1665
Q++FC + E+ PEY V+ F + +F+IEKI++I+N +L + + KK
Sbjct: 717 QEDFCFLSSKKYKLSEIHHLHPEYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKS 776
Query: 1666 TMDAKNGQTMNEKQLFHGTDAGSVPHVNRNGFNRSYAGKNAVAYGKGTYFAVNANYSAND 1725
M + K LF+ T V + N F+ + YGKG YFA +A YS +
Sbjct: 777 QMKEEG------KLLFYATSRAYVESICSNNFDSFLHETHENKYGKGIYFAKDAIYSHKN 830
Query: 1726 TYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPSLFVA 1785
P ++ +VL G +T GN + PP PQ +D+ D +PS+FV
Sbjct: 831 C---PYDAKNVVMFVAQVLVGKFTEGNITYTSPP---PQ-----FDSCVDTRSNPSVFVI 879
Query: 1786 FYDYQAYPEYLITF 1799
F Q YP+Y+I +
Sbjct: 880 FQKDQVYPQYVIEY 893
>gi|13569840 MACRO domain containing 1 [Homo sapiens]
Length = 325
Score = 84.0 bits (206), Expect = 1e-15
Identities = 54/176 (30%), Positives = 87/176 (49%), Gaps = 14/176 (7%)
Query: 808 QGDLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATIS 867
+ D+ +L VD +VNA+N L GG+ + +AAGP L +C + + G A I+
Sbjct: 158 RSDITKLEVDAIVNAANSSLLGGGGVDGCIHRAAGPLLTDECRTLQSCK----TGKAKIT 213
Query: 868 KAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIPAISSGVFG 927
+LP +VIH VGP G + LR SL L +++ RS+A P IS+GVFG
Sbjct: 214 GGYRLPAKYVIHTVGPIAYGEPSASQAAELRSCYLSSLDLLLEHRLRSVAFPCISTGVFG 273
Query: 928 FPLGRCVETIVSAIKENFQFKKDGHCLKEIYLVDVSEKTVEAFAEAVKTVFKATLP 983
+P E +++ ++E + KD V + F E + ++++ LP
Sbjct: 274 YPCEAAAEIVLATLREWLEQHKD----------KVDRLIICVFLEKDEDIYRSRLP 319
Score = 52.8 bits (125), Expect = 3e-06
Identities = 36/146 (24%), Positives = 68/146 (46%), Gaps = 5/146 (3%)
Query: 1018 LVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMGTVL 1077
L++ + + D +VN+ L L G + + AGP L +E T+ + G
Sbjct: 156 LLRSDITKLEVDAIVNAANSSL-LGGGGVDGCIHRAAGPLLTDECRTLQ---SCKTGKAK 211
Query: 1078 KTSSWNLDCRYVLHVVAP-EWRNGSTSSLKIMEDIIRECMEITESLSLKSIAFPAIGTGN 1136
T + L +YV+H V P + S S + +++ L+S+AFP I TG
Sbjct: 212 ITGGYRLPAKYVIHTVGPIAYGEPSASQAAELRSCYLSSLDLLLEHRLRSVAFPCISTGV 271
Query: 1137 LGFPKNIFAELIISEVFKFSSKNQLK 1162
G+P AE++++ + ++ +++ K
Sbjct: 272 FGYPCEAAAEIVLATLREWLEQHKDK 297
Score = 52.4 bits (124), Expect = 4e-06
Identities = 40/160 (25%), Positives = 70/160 (43%), Gaps = 12/160 (7%)
Query: 1235 DITKEEADVIVNSTSNSFNLKAGVSKAILECAGQNVERECSQQAQQRKNDYIITGGGFLR 1294
DITK E D IVN+ ++S GV I AG + EC + ITGG L
Sbjct: 160 DITKLEVDAIVNAANSSLLGGGGVDGCIHRAAGPLLTDECRTLQSCKTGKAKITGGYRLP 219
Query: 1295 CKNIIHVIG-----------GNDVKSSVSSVLQECEKKNYSSICLPAIGTGNAKQHPDKV 1343
K +IH +G +++S S L + S+ P I TG +
Sbjct: 220 AKYVIHTVGPIAYGEPSASQAAELRSCYLSSLDLLLEHRLRSVAFPCISTGVFGYPCEAA 279
Query: 1344 AEAIIDAIEDFVQKGSAQSVKKVKVVIFLPQVLDVFYANM 1383
AE ++ + +++++ V ++ + +FL + D++ + +
Sbjct: 280 AEIVLATLREWLEQ-HKDKVDRLIICVFLEKDEDIYRSRL 318
>gi|20336746 H2A histone family, member Y isoform 1 [Homo sapiens]
Length = 369
Score = 79.3 bits (194), Expect = 3e-14
Identities = 60/189 (31%), Positives = 85/189 (44%), Gaps = 5/189 (2%)
Query: 785 GSPA-GQKCFSRTVLAPGVVLIVQQGDLARLPVDVVVNASNEDLKHYGGLAAALSKAAGP 843
G+PA G S L G L V Q D+A + D VV+ +N D G + L K G
Sbjct: 177 GTPADGFTVLSTKSLFLGQKLQVVQADIASIDSDAVVHPTNTDFYIGGEVGNTLEKKGGK 236
Query: 844 ELQADCDQIVKREGRLLPGNATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQL 903
E ++ K+ G L A +S LP VIH P W A +C LL + V+
Sbjct: 237 EFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWG---ADKCEELLEKTVKN 293
Query: 904 SLCLAEKYKYRSIAIPAISSGVFGFPLGRCVETIVSAIKENFQFKKDGHCLKEIYLVDVS 963
L LA+ K +SIA P+I SG GFP + I+ AI F +K +Y V
Sbjct: 294 CLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYF-VSTMSSSIKTVYFVLFD 352
Query: 964 EKTVEAFAE 972
+++ + +
Sbjct: 353 SESIGIYVQ 361
Score = 76.6 bits (187), Expect = 2e-13
Identities = 46/177 (25%), Positives = 91/177 (51%), Gaps = 6/177 (3%)
Query: 1013 GLQMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEE-LDTVGQGVAV 1071
G ++ +V+ + + +D VV+ D + G + +L +K G E E L+ + +
Sbjct: 194 GQKLQVVQADIASIDSDAVVHPTNTDFYIG-GEVGNTLEKKGGKEFVEAVLELRKKNGPL 252
Query: 1072 SMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITESLSLKSIAFPA 1131
+ ++ L ++V+H +P W G+ +++E ++ C+ + + LKSIAFP+
Sbjct: 253 EVAGAAVSAGHGLPAKFVIHCNSPVW--GADKCEELLEKTVKNCLALADDKKLKSIAFPS 310
Query: 1132 IGTGNLGFPKNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQAFSDEFAR 1188
IG+G GFPK A+LI+ + + +++ V+F+L D E+I + E A+
Sbjct: 311 IGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLF--DSESIGIYVQEMAK 365
Score = 47.4 bits (111), Expect = 1e-04
Identities = 48/211 (22%), Positives = 86/211 (40%), Gaps = 28/211 (13%)
Query: 1201 KAKDTQGFYGTVSSPDS--------GVYEMKIGSIIF----QVASGDITKEEADVIVNST 1248
K+K QG +S DS G + S+ QV DI ++D +V+ T
Sbjct: 157 KSKKKQGEVSKAASADSTTEGTPADGFTVLSTKSLFLGQKLQVVQADIASIDSDAVVHPT 216
Query: 1249 SNSFNLKAGVSKAILECAGQNVERECSQQAQQRKNDYI------ITGGGFLRCKNIIHV- 1301
+ F + V + + G+ + ++KN + ++ G L K +IH
Sbjct: 217 NTDFYIGGEVGNTLEKKGGKEFVEAVLEL--RKKNGPLEVAGAAVSAGHGLPAKFVIHCN 274
Query: 1302 --IGGND-----VKSSVSSVLQECEKKNYSSICLPAIGTGNAKQHPDKVAEAIIDAIEDF 1354
+ G D ++ +V + L + K SI P+IG+G A+ I+ AI +
Sbjct: 275 SPVWGADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSY 334
Query: 1355 VQKGSAQSVKKVKVVIFLPQVLDVFYANMKK 1385
+ S+K V V+F + + ++ M K
Sbjct: 335 FVSTMSSSIKTVYFVLFDSESIGIYVQEMAK 365
>gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens]
Length = 425
Score = 74.7 bits (182), Expect = 8e-13
Identities = 48/136 (35%), Positives = 71/136 (52%), Gaps = 4/136 (2%)
Query: 808 QGDLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATIS 867
+GD+ L VD +VNA+N L GG+ + +AAGP L A+C + + G+A I+
Sbjct: 76 RGDITLLEVDAIVNAANASLLGGGGVDGCIHRAAGPCLLAECRNLNGCD----TGHAKIT 131
Query: 868 KAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIPAISSGVFG 927
LP +VIH VGP G+ L + SL L ++ RS+A P IS+G++G
Sbjct: 132 CGYDLPAKYVIHTVGPIARGHINGSHKEDLANCYKSSLKLVKENNIRSVAFPCISTGIYG 191
Query: 928 FPLGRCVETIVSAIKE 943
FP ++ IKE
Sbjct: 192 FPNEPAAVIALNTIKE 207
Score = 50.4 bits (119), Expect = 2e-05
Identities = 41/161 (25%), Positives = 74/161 (45%), Gaps = 9/161 (5%)
Query: 1000 KTSWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQ 1059
+TS K SL ++ L + + + D +VN+ L L G + + AGP L
Sbjct: 60 ETSQVKKSLTE----KVSLYRGDITLLEVDAIVNAANASL-LGGGGVDGCIHRAAGPCLL 114
Query: 1060 EELDTVGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKI-MEDIIRECMEI 1118
E + G T ++L +YV+H V P R S K + + + +++
Sbjct: 115 AECRNLN---GCDTGHAKITCGYDLPAKYVIHTVGPIARGHINGSHKEDLANCYKSSLKL 171
Query: 1119 TESLSLKSIAFPAIGTGNLGFPKNIFAELIISEVFKFSSKN 1159
+ +++S+AFP I TG GFP A + ++ + ++ +KN
Sbjct: 172 VKENNIRSVAFPCISTGIYGFPNEPAAVIALNTIKEWLAKN 212
Score = 45.1 bits (105), Expect = 6e-04
Identities = 41/163 (25%), Positives = 66/163 (40%), Gaps = 12/163 (7%)
Query: 1234 GDITKEEADVIVNSTSNSFNLKAGVSKAILECAGQNVERECSQQAQQRKNDYIITGGGFL 1293
GDIT E D IVN+ + S GV I AG + EC IT G L
Sbjct: 77 GDITLLEVDAIVNAANASLLGGGGVDGCIHRAAGPCLLAECRNLNGCDTGHAKITCGYDL 136
Query: 1294 RCKNIIHVIG-----------GNDVKSSVSSVLQECEKKNYSSICLPAIGTGNAKQHPDK 1342
K +IH +G D+ + S L+ ++ N S+ P I TG +
Sbjct: 137 PAKYVIHTVGPIARGHINGSHKEDLANCYKSSLKLVKENNIRSVAFPCISTGIYGFPNEP 196
Query: 1343 VAEAIIDAIEDFVQKGSAQSVKKVKVVIFLPQVLDVFYANMKK 1385
A ++ I++++ K + V ++ +FL ++ M +
Sbjct: 197 AAVIALNTIKEWLAK-NHHEVDRIIFCVFLEVDFKIYKKKMNE 238
>gi|4758496 H2A histone family, member Y isoform 2 [Homo sapiens]
Length = 371
Score = 73.2 bits (178), Expect = 2e-12
Identities = 46/180 (25%), Positives = 91/180 (50%), Gaps = 9/180 (5%)
Query: 1013 GLQMLLVKEGVQNA---KTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEE-LDTVGQG 1068
G ++ L+ + N + + ++N D+ L + L +L +K G E E L+ +
Sbjct: 193 GQKLNLIHSEISNLAGFEVEAIINPTNADIDL-KDDLGNTLEKKGGKEFVEAVLELRKKN 251
Query: 1069 VAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITESLSLKSIA 1128
+ + ++ L ++V+H +P W G+ +++E ++ C+ + + LKSIA
Sbjct: 252 GPLEVAGAAVSAGHGLPAKFVIHCNSPVW--GADKCEELLEKTVKNCLALADDKKLKSIA 309
Query: 1129 FPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQAFSDEFAR 1188
FP+IG+G GFPK A+LI+ + + +++ V+F+L D E+I + E A+
Sbjct: 310 FPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLF--DSESIGIYVQEMAK 367
Score = 73.2 bits (178), Expect = 2e-12
Identities = 49/163 (30%), Positives = 74/163 (45%), Gaps = 4/163 (2%)
Query: 810 DLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATISKA 869
+LA V+ ++N +N D+ L L K G E ++ K+ G L A +S
Sbjct: 205 NLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAG 264
Query: 870 GKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIPAISSGVFGFP 929
LP VIH P W A +C LL + V+ L LA+ K +SIA P+I SG GFP
Sbjct: 265 HGLPAKFVIHCNSPVWG---ADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFP 321
Query: 930 LGRCVETIVSAIKENFQFKKDGHCLKEIYLVDVSEKTVEAFAE 972
+ I+ AI F +K +Y V +++ + +
Sbjct: 322 KQTAAQLILKAISSYF-VSTMSSSIKTVYFVLFDSESIGIYVQ 363
Score = 43.1 bits (100), Expect = 0.002
Identities = 45/204 (22%), Positives = 86/204 (42%), Gaps = 20/204 (9%)
Query: 1196 SDKIPKAKDTQGFYGTVSSPDSGVYEMKIGSIIFQVASGDITKEEADVIVNSTSNSFNLK 1255
+D + GF TV S S K+ I ++++ + E + I+N T+ +LK
Sbjct: 170 ADSTTEGTPADGF--TVLSTKSLFLGQKLNLIHSEISN--LAGFEVEAIINPTNADIDLK 225
Query: 1256 AGVSKAILECAGQNVERECSQQAQQRKNDYI------ITGGGFLRCKNIIHV---IGGND 1306
+ + + G+ + ++KN + ++ G L K +IH + G D
Sbjct: 226 DDLGNTLEKKGGKEFVEAVLEL--RKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGAD 283
Query: 1307 -----VKSSVSSVLQECEKKNYSSICLPAIGTGNAKQHPDKVAEAIIDAIEDFVQKGSAQ 1361
++ +V + L + K SI P+IG+G A+ I+ AI + +
Sbjct: 284 KCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSS 343
Query: 1362 SVKKVKVVIFLPQVLDVFYANMKK 1385
S+K V V+F + + ++ M K
Sbjct: 344 SIKTVYFVLFDSESIGIYVQEMAK 367
>gi|93141020 H2A histone family, member Y isoform 2 [Homo sapiens]
Length = 371
Score = 73.2 bits (178), Expect = 2e-12
Identities = 46/180 (25%), Positives = 91/180 (50%), Gaps = 9/180 (5%)
Query: 1013 GLQMLLVKEGVQNA---KTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEE-LDTVGQG 1068
G ++ L+ + N + + ++N D+ L + L +L +K G E E L+ +
Sbjct: 193 GQKLNLIHSEISNLAGFEVEAIINPTNADIDL-KDDLGNTLEKKGGKEFVEAVLELRKKN 251
Query: 1069 VAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITESLSLKSIA 1128
+ + ++ L ++V+H +P W G+ +++E ++ C+ + + LKSIA
Sbjct: 252 GPLEVAGAAVSAGHGLPAKFVIHCNSPVW--GADKCEELLEKTVKNCLALADDKKLKSIA 309
Query: 1129 FPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQAFSDEFAR 1188
FP+IG+G GFPK A+LI+ + + +++ V+F+L D E+I + E A+
Sbjct: 310 FPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLF--DSESIGIYVQEMAK 367
Score = 73.2 bits (178), Expect = 2e-12
Identities = 49/163 (30%), Positives = 74/163 (45%), Gaps = 4/163 (2%)
Query: 810 DLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATISKA 869
+LA V+ ++N +N D+ L L K G E ++ K+ G L A +S
Sbjct: 205 NLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAG 264
Query: 870 GKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIPAISSGVFGFP 929
LP VIH P W A +C LL + V+ L LA+ K +SIA P+I SG GFP
Sbjct: 265 HGLPAKFVIHCNSPVWG---ADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFP 321
Query: 930 LGRCVETIVSAIKENFQFKKDGHCLKEIYLVDVSEKTVEAFAE 972
+ I+ AI F +K +Y V +++ + +
Sbjct: 322 KQTAAQLILKAISSYF-VSTMSSSIKTVYFVLFDSESIGIYVQ 363
Score = 43.1 bits (100), Expect = 0.002
Identities = 45/204 (22%), Positives = 86/204 (42%), Gaps = 20/204 (9%)
Query: 1196 SDKIPKAKDTQGFYGTVSSPDSGVYEMKIGSIIFQVASGDITKEEADVIVNSTSNSFNLK 1255
+D + GF TV S S K+ I ++++ + E + I+N T+ +LK
Sbjct: 170 ADSTTEGTPADGF--TVLSTKSLFLGQKLNLIHSEISN--LAGFEVEAIINPTNADIDLK 225
Query: 1256 AGVSKAILECAGQNVERECSQQAQQRKNDYI------ITGGGFLRCKNIIHV---IGGND 1306
+ + + G+ + ++KN + ++ G L K +IH + G D
Sbjct: 226 DDLGNTLEKKGGKEFVEAVLEL--RKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGAD 283
Query: 1307 -----VKSSVSSVLQECEKKNYSSICLPAIGTGNAKQHPDKVAEAIIDAIEDFVQKGSAQ 1361
++ +V + L + K SI P+IG+G A+ I+ AI + +
Sbjct: 284 KCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSS 343
Query: 1362 SVKKVKVVIFLPQVLDVFYANMKK 1385
S+K V V+F + + ++ M K
Sbjct: 344 SIKTVYFVLFDSESIGIYVQEMAK 367
>gi|93141018 H2A histone family, member Y isoform 3 [Homo sapiens]
Length = 372
Score = 73.2 bits (178), Expect = 2e-12
Identities = 46/180 (25%), Positives = 91/180 (50%), Gaps = 9/180 (5%)
Query: 1013 GLQMLLVKEGVQNA---KTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEE-LDTVGQG 1068
G ++ L+ + N + + ++N D+ L + L +L +K G E E L+ +
Sbjct: 194 GQKLNLIHSEISNLAGFEVEAIINPTNADIDL-KDDLGNTLEKKGGKEFVEAVLELRKKN 252
Query: 1069 VAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITESLSLKSIA 1128
+ + ++ L ++V+H +P W G+ +++E ++ C+ + + LKSIA
Sbjct: 253 GPLEVAGAAVSAGHGLPAKFVIHCNSPVW--GADKCEELLEKTVKNCLALADDKKLKSIA 310
Query: 1129 FPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQAFSDEFAR 1188
FP+IG+G GFPK A+LI+ + + +++ V+F+L D E+I + E A+
Sbjct: 311 FPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLF--DSESIGIYVQEMAK 368
Score = 73.2 bits (178), Expect = 2e-12
Identities = 49/163 (30%), Positives = 74/163 (45%), Gaps = 4/163 (2%)
Query: 810 DLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATISKA 869
+LA V+ ++N +N D+ L L K G E ++ K+ G L A +S
Sbjct: 206 NLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAG 265
Query: 870 GKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIPAISSGVFGFP 929
LP VIH P W A +C LL + V+ L LA+ K +SIA P+I SG GFP
Sbjct: 266 HGLPAKFVIHCNSPVWG---ADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFP 322
Query: 930 LGRCVETIVSAIKENFQFKKDGHCLKEIYLVDVSEKTVEAFAE 972
+ I+ AI F +K +Y V +++ + +
Sbjct: 323 KQTAAQLILKAISSYF-VSTMSSSIKTVYFVLFDSESIGIYVQ 364
Score = 43.1 bits (100), Expect = 0.002
Identities = 45/204 (22%), Positives = 86/204 (42%), Gaps = 20/204 (9%)
Query: 1196 SDKIPKAKDTQGFYGTVSSPDSGVYEMKIGSIIFQVASGDITKEEADVIVNSTSNSFNLK 1255
+D + GF TV S S K+ I ++++ + E + I+N T+ +LK
Sbjct: 171 ADSTTEGTPADGF--TVLSTKSLFLGQKLNLIHSEISN--LAGFEVEAIINPTNADIDLK 226
Query: 1256 AGVSKAILECAGQNVERECSQQAQQRKNDYI------ITGGGFLRCKNIIHV---IGGND 1306
+ + + G+ + ++KN + ++ G L K +IH + G D
Sbjct: 227 DDLGNTLEKKGGKEFVEAVLEL--RKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGAD 284
Query: 1307 -----VKSSVSSVLQECEKKNYSSICLPAIGTGNAKQHPDKVAEAIIDAIEDFVQKGSAQ 1361
++ +V + L + K SI P+IG+G A+ I+ AI + +
Sbjct: 285 KCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSS 344
Query: 1362 SVKKVKVVIFLPQVLDVFYANMKK 1385
S+K V V+F + + ++ M K
Sbjct: 345 SIKTVYFVLFDSESIGIYVQEMAK 368
>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase 2 [Homo sapiens]
Length = 1166
Score = 62.8 bits (151), Expect = 3e-09
Identities = 55/208 (26%), Positives = 92/208 (44%), Gaps = 32/208 (15%)
Query: 1619 VVELLPSDPEYNTVASKFNQTC-------------SHFRIEKIERIQNPDLWNSYQAKKK 1665
+++L P D E+ +V + T + + I KI+++ N LW Y ++K
Sbjct: 955 LIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRK 1014
Query: 1666 TMDAKNGQTMNEKQLFHGTDAGSVPHVN---RNGFNRSYAGKNAVAYGKGTYFAVNANYS 1722
+ +N NE+ LFHG+ P VN GF+ +A + +G G YFA N++ S
Sbjct: 1015 EVSEENHNHANERMLFHGS-----PFVNAIIHKGFDERHAYIGGM-FGAGIYFAENSSKS 1068
Query: 1723 ANDTYSRPDANG-------RKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDLYD-TVT 1774
Y G ++ + ++L T G L K +P + T
Sbjct: 1069 NQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGR 1128
Query: 1775 DNVHHPSL--FVAFYDYQAYPEYLITFR 1800
+V+ +L +V + QAYPEYLIT++
Sbjct: 1129 PSVNGLALAEYVIYRGEQAYPEYLITYQ 1156
>gi|8923920 H2A histone family, member Y2 [Homo sapiens]
Length = 372
Score = 61.2 bits (147), Expect = 9e-09
Identities = 44/143 (30%), Positives = 71/143 (49%), Gaps = 12/143 (8%)
Query: 1051 LEKAGPELQEELDTV-----GQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSL 1105
LEKAG + E L+TV QG + + + S L ++V+H P+W GS
Sbjct: 233 LEKAGGK--EFLETVKELRKSQG-PLEVAEAAVSQSSGLAAKFVIHCHIPQW--GSDKCE 287
Query: 1106 KIMEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKTLQ 1165
+ +E+ I+ C+ E LKS+AFP +G FPK A++ + + + +L+
Sbjct: 288 EQLEETIKNCLSAAEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFDDSSASSLK 347
Query: 1166 EVHFLLHPSDHENIQAFSDEFAR 1188
V+FLL D E+I + E A+
Sbjct: 348 NVYFLLF--DSESIGIYVQEMAK 368
Score = 59.7 bits (143), Expect = 2e-08
Identities = 47/193 (24%), Positives = 81/193 (41%), Gaps = 7/193 (3%)
Query: 783 EGGSPAGQKCFSRTVLAPGVVLIVQQGDLARLP---VDVVVNASNEDLKHYGGLAAALSK 839
E G G S L G L + Q D++ + V+ +V+ + ++ + AL K
Sbjct: 176 EDGPGDGFTILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHPTTAEIDLKEDIGKALEK 235
Query: 840 AAGPELQADCDQIVKREGRLLPGNATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRR 899
A G E ++ K +G L A +S++ L VIH P+W + +C L
Sbjct: 236 AGGKEFLETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWG---SDKCEEQLEE 292
Query: 900 AVQLSLCLAEKYKYRSIAIPAISSGVFGFPLGRCVETIVSAIKENFQFKKDGHCLKEIYL 959
++ L AE K +S+A P SG FP + + AI +F LK +Y
Sbjct: 293 TIKNCLSAAEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFD-DSSASSLKNVYF 351
Query: 960 VDVSEKTVEAFAE 972
+ +++ + +
Sbjct: 352 LLFDSESIGIYVQ 364
>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase [Homo sapiens]
Length = 1327
Score = 54.3 bits (129), Expect = 1e-06
Identities = 54/226 (23%), Positives = 90/226 (39%), Gaps = 60/226 (26%)
Query: 1615 QNFCVVELLPSDPEYNTVASKFNQTC-------------SHFRIEKIERIQNPDLWNSYQ 1661
Q +++L P D EY +V + T + + + +I+++ N L +
Sbjct: 1104 QGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRIQKVVNKKLRERFC 1163
Query: 1662 AKKKTMDAKNGQTMNEKQLFHGTDAGSVPHVN---RNGFNRSYAGKNAVAYGKGTYFAVN 1718
++K + +N NE+ LFHG+ P +N GF+ +A + +G G YFA N
Sbjct: 1164 HRQKEVSEENHNHHNERMLFHGS-----PFINAIIHKGFDERHAYIGGM-FGAGIYFAEN 1217
Query: 1719 ANYSANDTYSRPDANG------------RKHVYYVRVLTG---------IYTH---GNHS 1754
++ S Y G + + + RV G H G+HS
Sbjct: 1218 SSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAHAPPGHHS 1277
Query: 1755 LIVPPSKNPQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLITFR 1800
+I PS N + +V + QAYPEYLIT++
Sbjct: 1278 VIGRPSVNGLAYAE--------------YVIYRGEQAYPEYLITYQ 1309
>gi|207450721 ganglioside induced differentiation associated protein
2 isoform b [Homo sapiens]
Length = 496
Score = 52.0 bits (123), Expect = 5e-06
Identities = 36/127 (28%), Positives = 61/127 (48%), Gaps = 4/127 (3%)
Query: 804 LIVQQGDLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGN 863
+++ +GD+A L +VN SNE L ++ ++ AGP+L+ D + K +G G
Sbjct: 56 VVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKED---LQKLKG-CRTGE 111
Query: 864 ATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIPAISS 923
A ++K L +IH VGP++ L + L LA++ S+ I+S
Sbjct: 112 AKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINS 171
Query: 924 GVFGFPL 930
G+PL
Sbjct: 172 AKRGYPL 178
Score = 50.8 bits (120), Expect = 1e-05
Identities = 33/142 (23%), Positives = 68/142 (47%), Gaps = 5/142 (3%)
Query: 1015 QMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMG 1074
+++L K V +VN+ L + P+S+S+ AGP+L+E+L + G
Sbjct: 55 KVVLWKGDVALLNCTAIVNTSNESLT-DKNPVSESIFMLAGPDLKEDLQKLK---GCRTG 110
Query: 1075 TVLKTSSWNLDCRYVLHVVAPEWRNG-STSSLKIMEDIIRECMEITESLSLKSIAFPAIG 1133
T +NL R+++H V P++++ T++ + R +++ + S+ S+ F I
Sbjct: 111 EAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVIN 170
Query: 1134 TGNLGFPKNIFAELIISEVFKF 1155
+ G+P + + V +F
Sbjct: 171 SAKRGYPLEDATHIALRTVRRF 192
Score = 35.0 bits (79), Expect = 0.66
Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 11/104 (10%)
Query: 1234 GDITKEEADVIVNSTSNSFNLKAGVSKAILECAGQNVERECSQQAQQRKNDYIITGGGFL 1293
GD+ IVN+++ S K VS++I AG +++ + + R + +T G L
Sbjct: 61 GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL 120
Query: 1294 RCKNIIHVIG-----------GNDVKSSVSSVLQECEKKNYSSI 1326
+ IIH +G + + S +VLQ ++++ SS+
Sbjct: 121 AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSV 164
>gi|8923143 ganglioside induced differentiation associated protein 2
isoform a [Homo sapiens]
Length = 497
Score = 52.0 bits (123), Expect = 5e-06
Identities = 36/127 (28%), Positives = 61/127 (48%), Gaps = 4/127 (3%)
Query: 804 LIVQQGDLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGN 863
+++ +GD+A L +VN SNE L ++ ++ AGP+L+ D + K +G G
Sbjct: 56 VVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKED---LQKLKG-CRTGE 111
Query: 864 ATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIPAISS 923
A ++K L +IH VGP++ L + L LA++ S+ I+S
Sbjct: 112 AKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINS 171
Query: 924 GVFGFPL 930
G+PL
Sbjct: 172 AKRGYPL 178
Score = 50.8 bits (120), Expect = 1e-05
Identities = 33/142 (23%), Positives = 68/142 (47%), Gaps = 5/142 (3%)
Query: 1015 QMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMG 1074
+++L K V +VN+ L + P+S+S+ AGP+L+E+L + G
Sbjct: 55 KVVLWKGDVALLNCTAIVNTSNESLT-DKNPVSESIFMLAGPDLKEDLQKLK---GCRTG 110
Query: 1075 TVLKTSSWNLDCRYVLHVVAPEWRNG-STSSLKIMEDIIRECMEITESLSLKSIAFPAIG 1133
T +NL R+++H V P++++ T++ + R +++ + S+ S+ F I
Sbjct: 111 EAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVIN 170
Query: 1134 TGNLGFPKNIFAELIISEVFKF 1155
+ G+P + + V +F
Sbjct: 171 SAKRGYPLEDATHIALRTVRRF 192
Score = 35.0 bits (79), Expect = 0.66
Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 11/104 (10%)
Query: 1234 GDITKEEADVIVNSTSNSFNLKAGVSKAILECAGQNVERECSQQAQQRKNDYIITGGGFL 1293
GD+ IVN+++ S K VS++I AG +++ + + R + +T G L
Sbjct: 61 GDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNL 120
Query: 1294 RCKNIIHVIG-----------GNDVKSSVSSVLQECEKKNYSSI 1326
+ IIH +G + + S +VLQ ++++ SS+
Sbjct: 121 AARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSV 164
>gi|19923717 deltex 3-like [Homo sapiens]
Length = 740
Score = 45.8 bits (107), Expect = 4e-04
Identities = 22/52 (42%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
Query: 26 KLQMYFQSPKRSGGGECEV-RQDPRSPSRFLVFFYPEDVRQKVLERKNHELV 76
KL+ YFQS K SGGGEC V Q+ +P F V F +++VL++ H+++
Sbjct: 25 KLESYFQSSKSSGGGECTVSTQEHEAPGTFRVEFSERAAKERVLKKGEHQIL 76
>gi|188219599 N-myc and STAT interactor [Homo sapiens]
Length = 307
Score = 44.3 bits (103), Expect = 0.001
Identities = 55/241 (22%), Positives = 103/241 (42%), Gaps = 40/241 (16%)
Query: 61 EDVRQKVLERKNHELVW--QGKGTF----KLTVQLPATPDEIDHVFEEELLTKESKTKED 114
+D +Q + E E + Q KG K +QL +++ +E TKE + KED
Sbjct: 6 DDTQQILKEHSPDEFIKDEQNKGLIDEITKKNIQLKKEIQKLETELQEA--TKEFQIKED 63
Query: 115 VKEPDV------SEELDTKLP-LDGGLDKMEDIPEECENISSLVAFENLKANVTDIMLIL 167
+ E + + E D++L + +P E + +L+ FE +
Sbjct: 64 IPETKMKFLSVETPENDSQLSNISCSFQVSSKVPYEIQKGQALITFEKEE---------- 113
Query: 168 LVENISGLSNDDFQVEIIRDFDVAVVTFQKHIDT-IRFVDDCTKHHSIKQLQLSPRLLEV 226
+ +N+ +S Q I+D ++ V +++ +RF ++ ++ + E+
Sbjct: 114 VAQNVVSMSKHHVQ---IKDVNLEVTAKPVPLNSGVRF------QVYVEVSKMKINVTEI 164
Query: 227 TNTIRVENLPPGADDYSLKLFFENPYNGGGRVANVEYFPEESSALIEFFDRKVLDTIMAT 286
+T+R + + L+L F NGGG V V+Y + SA+I F + V D I+
Sbjct: 165 PDTLREDQMRD-----KLELSFSKSRNGGGEVDRVDYDRQSGSAVITFVEIGVADKILKK 219
Query: 287 K 287
K
Sbjct: 220 K 220
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 41.6 bits (96), Expect = 0.007
Identities = 39/174 (22%), Positives = 76/174 (43%), Gaps = 18/174 (10%)
Query: 60 PEDVRQKVLERKNHELVWQGKGTFKLTVQLPATPDEIDHVFEEELLTKESKTKEDVKEPD 119
P + Q ++E KN LV + + KL+ L + + E +LT+++ K + K +
Sbjct: 381 PSENLQSLME-KNQSLVEENE---KLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEE 436
Query: 120 VSEELDTKLPLDGGLDKMEDIPEECENISSLVAFENLKANVTDIMLILLVENISGLSNDD 179
+ + KL L ++ +ED E EN+ + + L ++D + + I +
Sbjct: 437 LRQHAACKLDLQKLVETLED-QELKENVEIICNLQQLITQLSDETVACMAAAIDTAVEQE 495
Query: 180 FQVEIIRDFDVAVVTFQKHIDTIRFVDDCTKHHSIKQLQLSPRLLEVTNTIRVE 233
QVE + T R D T H+++Q Q+S L+E+ + ++
Sbjct: 496 AQVETSPE-------------TSRSSDAFTTQHALRQAQMSKELVELNKALALK 536
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 40.0 bits (92), Expect = 0.020
Identities = 39/174 (22%), Positives = 76/174 (43%), Gaps = 18/174 (10%)
Query: 60 PEDVRQKVLERKNHELVWQGKGTFKLTVQLPATPDEIDHVFEEELLTKESKTKEDVKEPD 119
P + Q ++E KN LV + + KL+ L + + E +LT++ K + K +
Sbjct: 381 PSENLQSLME-KNQSLVEENE---KLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEE 436
Query: 120 VSEELDTKLPLDGGLDKMEDIPEECENISSLVAFENLKANVTDIMLILLVENISGLSNDD 179
+ + + KL L ++ +ED E EN+ + + L ++D + I ++
Sbjct: 437 LRQHVACKLDLQKLVETLED-QELKENVEIICNLQQLITQLSDETVACTAAAIDTAVEEE 495
Query: 180 FQVEIIRDFDVAVVTFQKHIDTIRFVDDCTKHHSIKQLQLSPRLLEVTNTIRVE 233
QVE + T R D T H++ Q Q+S ++E+ N + ++
Sbjct: 496 AQVETSPE-------------TSRSSDAFTTQHALHQAQMSKEVVELNNALALK 536
>gi|158634482 poly (ADP-ribose) polymerase family, member 3 isoform b
[Homo sapiens]
Length = 533
Score = 40.0 bits (92), Expect = 0.020
Identities = 43/163 (26%), Positives = 68/163 (41%), Gaps = 14/163 (8%)
Query: 1618 CVVELLPSD-PEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQAKKKTMDAKNGQTMN 1676
C ++LL S PEY + + QT S+ R ++ I W Q ++ + + N
Sbjct: 324 CQLQLLDSGAPEYKVIQTYLEQTGSNHRCPTLQHI-----WKVNQEGEEDRFQAHSKLGN 378
Query: 1677 EKQLFHGTDAGSVPHVNRNGFN-RSYAGKNAVAYGKGTYFAVNANYSANDTYSRPDANGR 1735
K L+HGT+ V + +G ++G GKG YFA + SA Y G
Sbjct: 379 RKLLWHGTNMAVVAAILTSGLRIMPHSGGRV---GKGIYFASENSKSAG--YVIGMKCGA 433
Query: 1736 KHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVH 1778
HV Y + G G I + + ++P +D+V H
Sbjct: 434 HHVGY--MFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGH 474
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,264,309
Number of Sequences: 37866
Number of extensions: 3111550
Number of successful extensions: 9912
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 9664
Number of HSP's gapped (non-prelim): 169
length of query: 1801
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1684
effective length of database: 13,817,196
effective search space: 23268158064
effective search space used: 23268158064
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.