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Search of human proteins with 154426292
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154426292 arachidonate 12-lipoxygenase [Homo sapiens]
(663 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154426292 arachidonate 12-lipoxygenase [Homo sapiens] 1377 0.0
gi|40316937 arachidonate 15-lipoxygenase [Homo sapiens] 900 0.0
gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens] 522 e-148
gi|85067501 arachidonate 15-lipoxygenase, second type isoform d ... 467 e-131
gi|4502053 arachidonate 12-lipoxygenase, 12R type [Homo sapiens] 464 e-131
gi|182765464 arachidonate lipoxygenase 3 [Homo sapiens] 462 e-130
gi|85067499 arachidonate 15-lipoxygenase, second type isoform a ... 422 e-118
gi|85067503 arachidonate 15-lipoxygenase, second type isoform b ... 369 e-102
gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens] 47 6e-05
gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo ... 47 6e-05
gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo ... 47 6e-05
gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sap... 42 0.002
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap... 42 0.002
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 36 0.099
gi|222144247 dynein heavy chain domain 1 isoform 2 [Homo sapiens] 36 0.099
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 33 0.84
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 33 0.84
gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo sap... 32 1.9
gi|55953110 retinoblastoma protein-binding zinc finger protein i... 32 1.9
gi|20336260 retinoblastoma protein-binding zinc finger protein i... 32 1.9
gi|20336258 retinoblastoma protein-binding zinc finger protein i... 32 1.9
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 31 3.2
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 31 3.2
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 31 3.2
gi|14150070 coiled-coil-helix-coiled-coil-helix domain containin... 31 4.2
gi|66346715 mature T-cell proliferation 1 [Homo sapiens] 30 9.3
gi|239756418 PREDICTED: hypothetical protein [Homo sapiens] 30 9.3
gi|239750947 PREDICTED: hypothetical protein XP_002347611 [Homo ... 30 9.3
gi|239745340 PREDICTED: hypothetical protein XP_002343429 [Homo ... 30 9.3
gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens] 30 9.3
>gi|154426292 arachidonate 12-lipoxygenase [Homo sapiens]
Length = 663
Score = 1377 bits (3565), Expect = 0.0
Identities = 663/663 (100%), Positives = 663/663 (100%)
Query: 1 MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRPARGEEEEFDHDVAEDLGLL 60
MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRPARGEEEEFDHDVAEDLGLL
Sbjct: 1 MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRPARGEEEEFDHDVAEDLGLL 60
Query: 61 QFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLPEGTARLPGDNA 120
QFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLPEGTARLPGDNA
Sbjct: 61 QFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLPEGTARLPGDNA 120
Query: 121 LDMFQKHREKELKDRQQIYCWATWKEGLPLTIAADRKDDLPPNMRFHEEKRLDFEWTLKA 180
LDMFQKHREKELKDRQQIYCWATWKEGLPLTIAADRKDDLPPNMRFHEEKRLDFEWTLKA
Sbjct: 121 LDMFQKHREKELKDRQQIYCWATWKEGLPLTIAADRKDDLPPNMRFHEEKRLDFEWTLKA 180
Query: 181 GALEMALKRVYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFSYQFLNGANPML 240
GALEMALKRVYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFSYQFLNGANPML
Sbjct: 181 GALEMALKRVYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFSYQFLNGANPML 240
Query: 241 LRRSTSLPSRLVLPSGMEELQAQLEKELQNGSLFEADFILLDGIPANVIRGEKQYLAAPL 300
LRRSTSLPSRLVLPSGMEELQAQLEKELQNGSLFEADFILLDGIPANVIRGEKQYLAAPL
Sbjct: 241 LRRSTSLPSRLVLPSGMEELQAQLEKELQNGSLFEADFILLDGIPANVIRGEKQYLAAPL 300
Query: 301 VMLKMEPNGKLQPMVIQIQPPNPSSPTPTLFLPSDPPLAWLLAKSWVRNSDFQLHEIQYH 360
VMLKMEPNGKLQPMVIQIQPPNPSSPTPTLFLPSDPPLAWLLAKSWVRNSDFQLHEIQYH
Sbjct: 301 VMLKMEPNGKLQPMVIQIQPPNPSSPTPTLFLPSDPPLAWLLAKSWVRNSDFQLHEIQYH 360
Query: 361 LLNTHLVAEVIAVATMRCLPGLHPIFKFLIPHIRYTMEINTRARTQLISDGGIFDKAVST 420
LLNTHLVAEVIAVATMRCLPGLHPIFKFLIPHIRYTMEINTRARTQLISDGGIFDKAVST
Sbjct: 361 LLNTHLVAEVIAVATMRCLPGLHPIFKFLIPHIRYTMEINTRARTQLISDGGIFDKAVST 420
Query: 421 GGGGHVQLLRRAAAQLTYCSLCPPDDLADRGLLGLPGALYAHDALRLWEIIARYVEGIVH 480
GGGGHVQLLRRAAAQLTYCSLCPPDDLADRGLLGLPGALYAHDALRLWEIIARYVEGIVH
Sbjct: 421 GGGGHVQLLRRAAAQLTYCSLCPPDDLADRGLLGLPGALYAHDALRLWEIIARYVEGIVH 480
Query: 481 LFYQRDDIVKGDPELQAWCREITEVGLCQAQDRGFPVSFQSQSQLCHFLTMCVFTCTAQH 540
LFYQRDDIVKGDPELQAWCREITEVGLCQAQDRGFPVSFQSQSQLCHFLTMCVFTCTAQH
Sbjct: 481 LFYQRDDIVKGDPELQAWCREITEVGLCQAQDRGFPVSFQSQSQLCHFLTMCVFTCTAQH 540
Query: 541 AAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMAISWHLSRR 600
AAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMAISWHLSRR
Sbjct: 541 AAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMAISWHLSRR 600
Query: 601 QPDMVPLGHHKEKYFSGPKPKAVLNQFRTDLEKLEKEITARNEQLDWPYEYLKPSCIENS 660
QPDMVPLGHHKEKYFSGPKPKAVLNQFRTDLEKLEKEITARNEQLDWPYEYLKPSCIENS
Sbjct: 601 QPDMVPLGHHKEKYFSGPKPKAVLNQFRTDLEKLEKEITARNEQLDWPYEYLKPSCIENS 660
Query: 661 VTI 663
VTI
Sbjct: 661 VTI 663
>gi|40316937 arachidonate 15-lipoxygenase [Homo sapiens]
Length = 662
Score = 900 bits (2326), Expect = 0.0
Identities = 434/663 (65%), Positives = 528/663 (79%), Gaps = 1/663 (0%)
Query: 1 MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRPARGEEEEFDHDVAEDLGLL 60
MG YRIRV+TGA L++GS N+VQLWLVG GEA L +L PARG+E E +V E LG L
Sbjct: 1 MGLYRIRVSTGASLYAGSNNQVQLWLVGQHGEAALGKRLWPARGKETELKVEVPEYLGPL 60
Query: 61 QFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLPEGTARLPGDNA 120
FV+LRK H L DDAWFC+ I+VQGPGA EV FPCYRWV+G +LSLPEGT R G++
Sbjct: 61 LFVKLRKRHLLKDDAWFCNWISVQGPGAGDEVRFPCYRWVEGNGVLSLPEGTGRTVGEDP 120
Query: 121 LDMFQKHREKELKDRQQIYCWATWKEGLPLTIAADRKDDLPPNMRFHEEKRLDFEWTLKA 180
+FQKHRE+EL++R+++Y W WK+GL L +A + DLP + RF E+KR+DFE +L
Sbjct: 121 QGLFQKHREEELEERRKLYRWGNWKDGLILNMAGAKLYDLPVDERFLEDKRVDFEVSLAK 180
Query: 181 GALEMALKRVYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFSYQFLNGANPML 240
G ++A+K +L+ W L+DF++IFW +S LAE+VR W++D LF YQFLNGANP++
Sbjct: 181 GLADLAIKDSLNVLTCWKDLDDFNRIFWCGQSKLAERVRDSWKEDALFGYQFLNGANPVV 240
Query: 241 LRRSTSLPSRLVLPSGMEELQAQLEKELQNGSLFEADFILLDGIPANVIRGEKQYLAAPL 300
LRRS LP+RLV P GMEELQAQLEKEL+ G+LFEADF LLDGI ANVI +Q+LAAPL
Sbjct: 241 LRRSAHLPARLVFPPGMEELQAQLEKELEGGTLFEADFSLLDGIKANVILCSQQHLAAPL 300
Query: 301 VMLKMEPNGKLQPMVIQIQPPNPSSPTPTLFLPSDPPLAWLLAKSWVRNSDFQLHEIQYH 360
VMLK++P+GKL PMVIQ+Q P SP P LFLP+DPP+AWLLAK WVR+SDFQLHE+Q H
Sbjct: 301 VMLKLQPDGKLLPMVIQLQLPRTGSPPPPLFLPTDPPMAWLLAKCWVRSSDFQLHELQSH 360
Query: 361 LLNTHLVAEVIAVATMRCLPGLHPIFKFLIPHIRYTMEINTRARTQLISDGGIFDKAVST 420
LL HL+AEVI VATMRCLP +HPIFK +IPH+RYT+EIN RART L+SD GIFD+ +ST
Sbjct: 361 LLRGHLMAEVIVVATMRCLPSIHPIFKLIIPHLRYTLEINVRARTGLVSDMGIFDQIMST 420
Query: 421 GGGGHVQLLRRAAAQLTYCSLCPPDDLADRGLLGLPGALYAHDALRLWEIIARYVEGIVH 480
GGGGHVQLL++A A LTY S CPPDDLADRGLLG+ + YA DALRLWEII RYVEGIV
Sbjct: 421 GGGGHVQLLKQAGAFLTYSSFCPPDDLADRGLLGVKSSFYAQDALRLWEIIYRYVEGIVS 480
Query: 481 LFYQRDDIVKGDPELQAWCREITEVGLCQAQDRGFPVSFQSQSQLCHFLTMCVFTCTAQH 540
L Y+ D VK DPELQ WCREITE+GL AQDRGFPVS Q++ Q+CHF+TMC+FTCT QH
Sbjct: 481 LHYKTDVAVKDDPELQTWCREITEIGLQGAQDRGFPVSLQARDQVCHFVTMCIFTCTGQH 540
Query: 541 AAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMAISWHLSRR 600
A+++ GQLDWY+WVPNAPCTMR+PPPTTK D T+ TVM +LP+ QA LQM+I+W L RR
Sbjct: 541 ASVHLGQLDWYSWVPNAPCTMRLPPPTTK-DATLETVMATLPNFHQASLQMSITWQLGRR 599
Query: 601 QPDMVPLGHHKEKYFSGPKPKAVLNQFRTDLEKLEKEITARNEQLDWPYEYLKPSCIENS 660
QP MV +G H+E+YFSGP+PKAVL +FR +L L+KEI RN +LD PYEYL+PS +ENS
Sbjct: 600 QPVMVAVGQHEEEYFSGPEPKAVLKKFREELAALDKEIEIRNAKLDMPYEYLRPSVVENS 659
Query: 661 VTI 663
V I
Sbjct: 660 VAI 662
>gi|4502057 arachidonate 5-lipoxygenase [Homo sapiens]
Length = 674
Score = 522 bits (1344), Expect = e-148
Identities = 282/678 (41%), Positives = 411/678 (60%), Gaps = 19/678 (2%)
Query: 1 MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRP-----ARGEEEEFDHDVAE 55
M Y + VATG+ F+G+ + + L LVG+ G +E L +P RG + +D V E
Sbjct: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60
Query: 56 DLGLLQFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLPEGTARL 115
+LG +Q VR+ K + ++D W+ IT++ P + FPCYRW+ G+ + L +G A+L
Sbjct: 61 ELGEIQLVRIEKRKYWLNDDWYLKYITLKTPHG-DYIEFPCYRWITGDVEVVLRDGRAKL 119
Query: 116 PGDNALDMFQKHREKELKDRQQIYCWATWKEGLPLTIAADRKDDLPPNMRFHEEKRLDFE 175
D+ + + ++HR KEL+ RQ+ Y W W G PL+I A DLP +++F EK +DF
Sbjct: 120 ARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFV 179
Query: 176 WTLKAGALEMALKR-VYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFSYQFLN 234
+ + R ++ SSWN DF++IF + ++E+V WQ+D +F YQFLN
Sbjct: 180 LNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLN 239
Query: 235 GANPMLLRRSTSLPSRLVLPSGMEEL----QAQLEKELQNGSLFEADFILLDGIPANVIR 290
G NP+L+RR T LP +L + + M E Q LE+E+Q G++F DF LLDGI AN
Sbjct: 240 GCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTD 299
Query: 291 G-EKQYLAAPLVMLKMEPNGKLQPMVIQI-QPPNPSSPTPTLFLPSDPPLAWLLAKSWVR 348
Q+LAAP+ +L K+ P+ IQ+ Q P +P +FLPSD WLLAK WVR
Sbjct: 300 PCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENP---IFLPSDAKYDWLLAKIWVR 356
Query: 349 NSDFQLHEIQYHLLNTHLVAEVIAVATMRCLPGLHPIFKFLIPHIRYTMEINTRARTQLI 408
+SDF +H+ HLL THLV+EV +A R LP +HPIFK L+ H+R+T+ INT+AR QLI
Sbjct: 357 SSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLI 416
Query: 409 SDGGIFDKAVSTGGGGHVQLLRRAAAQLTYCSLCPPDDLADRGLLG---LPGALYAHDAL 465
+ G+FDKA +TGGGGHVQ+++RA LTY SLC P+ + RG+ +P Y D L
Sbjct: 417 CECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGL 476
Query: 466 RLWEIIARYVEGIVHLFYQRDDIVKGDPELQAWCREITEVGLCQAQDRGFPVSFQSQSQL 525
+WE I + +V ++Y+ D +V+ DPELQ + ++ G+ + GFP S +S+ QL
Sbjct: 477 LVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQL 536
Query: 526 CHFLTMCVFTCTAQHAAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVR 585
+LT+ +FT +AQHAA+N GQ DW +W+PNAP TMR PPPT K VT+ ++ +LPD
Sbjct: 537 SEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRG 596
Query: 586 QACLQMAISWHLSRRQPDMVPLGHHKEKYFSGPKPKAVLNQFRTDLEKLEKEITARNEQL 645
++C + W LS+ Q + + LG + E++F K + +FR +LE + I RN++
Sbjct: 597 RSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNKKK 656
Query: 646 DWPYEYLKPSCIENSVTI 663
PY YL P I NSV I
Sbjct: 657 QLPYYYLSPDRIPNSVAI 674
>gi|85067501 arachidonate 15-lipoxygenase, second type isoform d
[Homo sapiens]
Length = 676
Score = 467 bits (1202), Expect = e-131
Identities = 255/680 (37%), Positives = 384/680 (56%), Gaps = 21/680 (3%)
Query: 1 MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAEL----ELQLRPARGEEEEFDHDVAED 56
M +R+RV+TG +G++++V + +VGTRGE+ L G EE+F + ED
Sbjct: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60
Query: 57 LGLLQFVRLRKHHW-------LVDDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLP 109
+G + +R+ K L DAWFC + P + FPCY+W++G L L
Sbjct: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRG-GHLLFPCYQWLEGAGTLVLQ 119
Query: 110 EGTARLPGDNALDMFQKHREKELKDRQQIYCWATWKEGLPLTIAADRKDDLPPNMRFHEE 169
EGTA++ + + Q+ R++EL+ RQ++Y W + G P + +DL N+++
Sbjct: 120 EGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTA 179
Query: 170 KRLDFEWTLKAGALEMALKRVYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFS 229
K +F + EM +K + W L + +IF +++ AE + WQ+D F+
Sbjct: 180 KNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFA 239
Query: 230 YQFLNGANPMLLRRSTSLPSRLVLPSGMEELQ----AQLEKELQNGSLFEADFILLDGIP 285
QFLNG NP+L+RR LP + M L+ EL+ GSLF D +L GI
Sbjct: 240 SQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQ 299
Query: 286 ANVIRGEKQYLAAPLVMLKMEPN-GKLQPMVIQI-QPPNPSSPTPTLFLPSDPPLAWLLA 343
NVI G+ Q+ AAP+ +L P G L P+ IQ+ Q P P+SP +FLP+D WLLA
Sbjct: 300 TNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSP---IFLPTDDKWDWLLA 356
Query: 344 KSWVRNSDFQLHEIQYHLLNTHLVAEVIAVATMRCLPGLHPIFKFLIPHIRYTMEINTRA 403
K+WVRN++F HE HLL++HL+ EV +AT+R LP HP+FK LIPH RYT+ INT A
Sbjct: 357 KTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLA 416
Query: 404 RTQLISDGGIFDKAVSTGGGGHVQLLRRAAAQLTYCSLCPPDDLADRGLLGLPGALYAHD 463
R LI G + D++ G G +L++R QL Y LC P+D+ RG+ +PG Y D
Sbjct: 417 RELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDD 476
Query: 464 ALRLWEIIARYVEGIVHLFYQRDDIVKGDPELQAWCREITEVGLCQAQDRGFPVSFQSQS 523
+++W + R+V I+ ++Y D+ V+ D ELQAW REI G + G P S +++
Sbjct: 477 GMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETRE 536
Query: 524 QLCHFLTMCVFTCTAQHAAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPD 583
L ++TM +FTC+A+HAA++ GQ D AW+PN P +M++PPPT+K T + +LP
Sbjct: 537 ALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPP 596
Query: 584 VRQACLQMAISWHLSRRQPDMVPLGHHKEKYFSGPKPKAVLNQFRTDLEKLEKEITARNE 643
V C + W LS+ D PLG + +++F+ P+ + F++ L ++ + I RN+
Sbjct: 597 VNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQ 656
Query: 644 QLDWPYEYLKPSCIENSVTI 663
L PY YL P IENSV+I
Sbjct: 657 GLVLPYTYLDPPLIENSVSI 676
>gi|4502053 arachidonate 12-lipoxygenase, 12R type [Homo sapiens]
Length = 701
Score = 464 bits (1195), Expect = e-131
Identities = 258/709 (36%), Positives = 391/709 (55%), Gaps = 54/709 (7%)
Query: 1 MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRPAR----GEEEEFDHDVAED 56
M Y++RVATG L SG+ + + L +VGT+GE+ +L R G ++ +D
Sbjct: 1 MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQD 60
Query: 57 LGLLQFVRLRKHHWLV--DDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLPEGTAR 114
LG L +RL K + D W+C+ + + P FP Y+W+ G + L+L E T +
Sbjct: 61 LGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGRI-YHFPAYQWMDGYETLALREATGK 119
Query: 115 LPGDNALDMFQKHREKELKDRQQIYCWATWKEGLPL---------TIAADRKDDLPP--- 162
D++L + +HR++E++ +Q Y W + GLP + R + P
Sbjct: 120 TTADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHRNPNRPEWNG 179
Query: 163 -------------------NMRFHEEKRLDFEWTLKAGALEMALKRVYTLLSSWNCLEDF 203
N+R+ K F L AL ++ + SW L+D
Sbjct: 180 YIPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCKHSWKRLKDI 239
Query: 204 DQIFWGQKSALAEKVRQCWQDDELFSYQFLNGANPMLLRRSTSLPSRLVLPSGMEE---- 259
+IF G+KS ++E V + W +D F YQ+LNG NP L+RR T +P + + M
Sbjct: 240 RKIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVTDDMVAPFLG 299
Query: 260 ----LQAQLEKELQNGSLFEADFILLDGIPANVIRGEKQYLAAPLVMLKMEPNGKLQPMV 315
LQA+LEK G+++ AD+ +++GIP + G KQ+ APL +L P GK+ P+
Sbjct: 300 EGTCLQAELEK----GNIYLADYRIMEGIPTVELSGRKQHHCAPLCLLHFGPEGKMMPIA 355
Query: 316 IQI-QPPNPSSPTPTLFLPSDPPLAWLLAKSWVRNSDFQLHEIQYHLLNTHLVAEVIAVA 374
IQ+ Q P P P +FLPSD WLLAK+WVR ++F HE HLL THL+AE +A
Sbjct: 356 IQLSQTPGPDCP---IFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFCLA 412
Query: 375 TMRCLPGLHPIFKFLIPHIRYTMEINTRARTQLISDGGIFDKAVSTGGGGHVQLLRRAAA 434
+R LP HP++K LIPH RYT++IN+ R L+++GG+ K +S G G ++ RA +
Sbjct: 413 LLRNLPMCHPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRALS 472
Query: 435 QLTYCSLCPPDDLADRGLLGLPGALYAHDALRLWEIIARYVEGIVHLFYQRDDIVKGDPE 494
+LTY SL P+D +RG+ LPG Y D+L +W + +YV I+ +Y D V+GDPE
Sbjct: 473 ELTYDSLYLPNDFVERGVQDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGDPE 532
Query: 495 LQAWCREITEVGLCQAQDRGFPVSFQSQSQLCHFLTMCVFTCTAQHAAINQGQLDWYAWV 554
LQ+W +EI + L + GFP ++ +L ++T+ ++TC+A+HAA+N GQ+++ AW+
Sbjct: 533 LQSWVQEIFKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTAWM 592
Query: 555 PNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMAISWHLSRRQPDMVPLGHHKEKY 614
PN P +MR PP TK T+ T M +LPDV+ C+ + + W LSR D PLGH + +
Sbjct: 593 PNFPASMRNPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPDIH 652
Query: 615 FSGPKPKAVLNQFRTDLEKLEKEITARNEQLDWPYEYLKPSCIENSVTI 663
F P+ + FR L ++ +I RN+ L PY YL P IENS++I
Sbjct: 653 FVEEAPRRSIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI 701
>gi|182765464 arachidonate lipoxygenase 3 [Homo sapiens]
Length = 711
Score = 462 bits (1189), Expect = e-130
Identities = 260/715 (36%), Positives = 385/715 (53%), Gaps = 56/715 (7%)
Query: 1 MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRPAR----GEEEEFDHDVAED 56
M YR+ V TG +L +G+ + + + LVGT GE+ + R R G +++ +
Sbjct: 1 MAVYRLCVTTGPYLRAGTLDNISVTLVGTCGESPKQRLDRMGRDFAPGSVQKYKVRCTAE 60
Query: 57 LGLLQFVRLRKHHWLV--DDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLPEGTAR 114
LG L +R+ K + D+W+C RI V P FPCY+W++G + L GTAR
Sbjct: 61 LGELLLLRVHKERYAFFRKDSWYCSRICVTEPDGSVS-HFPCYQWIEGYCTVELRPGTAR 119
Query: 115 LPGDNALDMFQKHREKELKDRQQIYCWATWKEGLPL---------------------TIA 153
++L + HR +EL+ RQ+ Y W + G P T
Sbjct: 120 TICQDSLPLLLDHRTRELRARQECYRWKIYAPGFPCMVDVNSFQEMESDKKFALTKTTTC 179
Query: 154 ADRKD--------------DLP------PNMRFHEEKRLDFEWTLKAGALEMALKRVYTL 193
D+ D D+P PN+R+ K + + +L M L+ +
Sbjct: 180 VDQGDSSGNRYLPGFPMKIDIPSLMYMEPNVRYSATKTISLLFNAIPASLGMKLRGLLDR 239
Query: 194 LSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFSYQFLNGANPMLLRRSTSLPSRLVL 253
SW L+D IFW K+ + V + W +D F YQ+LNG NP++L +SLPS+L +
Sbjct: 240 KGSWKKLDDMQNIFWCHKTFTTKYVTEHWCEDHFFGYQYLNGVNPVMLHCISSLPSKLPV 299
Query: 254 PSGM-EELQAQ---LEKELQNGSLFEADFILLDGIPANVIRGEKQYLAAPLVMLKMEPNG 309
+ M L Q L+ EL+ G++F AD+ +L P + + G +QY+AAPL +L + P G
Sbjct: 300 TNDMVAPLLGQDTCLQTELERGNIFLADYWILAEAPTHCLNGRQQYVAAPLCLLWLSPQG 359
Query: 310 KLQPMVIQI-QPPNPSSPTPTLFLPSDPPLAWLLAKSWVRNSDFQLHEIQYHLLNTHLVA 368
L P+ IQ+ Q P P SP +FLP+D WLLAK+WVRNS+F +HE H L THL+
Sbjct: 360 ALVPLAIQLSQTPGPDSP---IFLPTDSEWDWLLAKTWVRNSEFLVHENNTHFLCTHLLC 416
Query: 369 EVIAVATMRCLPGLHPIFKFLIPHIRYTMEINTRARTQLISDGGIFDKAVSTGGGGHVQL 428
E A+AT+R LP HPI+K L+PH RYT+++NT AR L++ G+ D+ S G G + L
Sbjct: 417 EAFAMATLRQLPLCHPIYKLLLPHTRYTLQVNTIARATLLNPEGLVDQVTSIGRQGLIYL 476
Query: 429 LRRAAAQLTYCSLCPPDDLADRGLLGLPGALYAHDALRLWEIIARYVEGIVHLFYQRDDI 488
+ A TY + C PD L RG+L +P Y D L++W I +V IV +Y D
Sbjct: 477 MSTGLAHFTYTNFCLPDSLRARGVLAIPNYHYRDDGLKIWAAIESFVSEIVGYYYPSDAS 536
Query: 489 VKGDPELQAWCREITEVGLCQAQDRGFPVSFQSQSQLCHFLTMCVFTCTAQHAAINQGQL 548
V+ D ELQAW EI + GFP + ++ FLT +F C+AQHAA+N GQ
Sbjct: 537 VQQDSELQAWTGEIFAQAFLGRESSGFPSRLCTPGEMVKFLTAIIFNCSAQHAAVNSGQH 596
Query: 549 DWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMAISWHLSRRQPDMVPLG 608
D+ AW+PNAP +MR PPP TK T+ T + +LP+V +C + + W +S+ D PLG
Sbjct: 597 DFGAWMPNAPSSMRQPPPQTKGTTTLKTYLDTLPEVNISCNNLLLFWLVSQEPKDQRPLG 656
Query: 609 HHKEKYFSGPKPKAVLNQFRTDLEKLEKEITARNEQLDWPYEYLKPSCIENSVTI 663
+ +++F+ P+ + F++ L ++ ++I RN+ L PY YL P IENSV+I
Sbjct: 657 TYPDEHFTEEAPRRSIAAFQSRLAQISRDIQERNQGLALPYTYLDPPLIENSVSI 711
>gi|85067499 arachidonate 15-lipoxygenase, second type isoform a
[Homo sapiens]
Length = 647
Score = 422 bits (1085), Expect = e-118
Identities = 242/682 (35%), Positives = 367/682 (53%), Gaps = 54/682 (7%)
Query: 1 MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAEL----ELQLRPARGEEEEFDHDVAED 56
M +R+RV+TG +G++++V + +VGTRGE+ L G EE+F + ED
Sbjct: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60
Query: 57 LGLLQFVRLRKHHW-------LVDDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLP 109
+G + +R+ K L DAWFC + P + FPCY+W++G L L
Sbjct: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRG-GHLLFPCYQWLEGAGTLVLQ 119
Query: 110 EGTARLPGDNALDMFQKHREKELKDRQQIYCWATWKEGLPLTIAADRKDDLPPNMRFHEE 169
EGTA++ + + Q+ R++EL+ RQ++Y W + G P + +DL N+++
Sbjct: 120 EGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTA 179
Query: 170 KRLDFEWTLKAGALEMALKRVYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFS 229
K +F + EM +K + W L + +IF +++ AE + WQ+D F+
Sbjct: 180 KNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFA 239
Query: 230 YQFLNGANPMLLRRSTSLPSRLVLPSGMEELQ----AQLEKELQNGSLFEADFILLDGIP 285
QFLNG NP+L+RR LP + M L+ EL+ GSLF D +L GI
Sbjct: 240 SQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQ 299
Query: 286 ANVIRGEKQYLAAPLVMLKMEPN-GKLQPMVIQI-QPPNPSSPTPTLFLPSDPPLAWLLA 343
NVI G+ Q+ AAP+ +L P G L P+ IQ+ Q P P+SP +FLP+D WLLA
Sbjct: 300 TNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSP---IFLPTDDKWDWLLA 356
Query: 344 KSWVRNSDFQLHEIQYHLLNTHLVAEVIAVATMRCLPGLHPIFKFLIPHIRYTMEINTRA 403
K+WVRN++F HE HLL++HL+ EV +AT+R LP HP+FK
Sbjct: 357 KTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFK---------------- 400
Query: 404 RTQLISDGGIFDKAVSTGGG--GHVQLLRRAAAQLTYCSLCPPDDLADRGLLGLPGALYA 461
STG G G +L++R QL Y LC P+D+ RG+ +PG Y
Sbjct: 401 ---------------STGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYR 445
Query: 462 HDALRLWEIIARYVEGIVHLFYQRDDIVKGDPELQAWCREITEVGLCQAQDRGFPVSFQS 521
D +++W + R+V I+ ++Y D+ V+ D ELQAW REI G + G P S ++
Sbjct: 446 DDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLET 505
Query: 522 QSQLCHFLTMCVFTCTAQHAAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSL 581
+ L ++TM +FTC+A+HAA++ GQ D AW+PN P +M++PPPT+K T + +L
Sbjct: 506 REALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATL 565
Query: 582 PDVRQACLQMAISWHLSRRQPDMVPLGHHKEKYFSGPKPKAVLNQFRTDLEKLEKEITAR 641
P V C + W LS+ D PLG + +++F+ P+ + F++ L ++ + I R
Sbjct: 566 PPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQER 625
Query: 642 NEQLDWPYEYLKPSCIENSVTI 663
N+ L PY YL P IENSV+I
Sbjct: 626 NQGLVLPYTYLDPPLIENSVSI 647
>gi|85067503 arachidonate 15-lipoxygenase, second type isoform b
[Homo sapiens]
Length = 602
Score = 369 bits (948), Expect = e-102
Identities = 226/682 (33%), Positives = 343/682 (50%), Gaps = 99/682 (14%)
Query: 1 MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAEL----ELQLRPARGEEEEFDHDVAED 56
M +R+RV+TG +G++++V + +VGTRGE+ L G EE+F + ED
Sbjct: 1 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED 60
Query: 57 LGLLQFVRLRKHHW-------LVDDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLP 109
+G + +R+ K L DAWFC + P + FPCY+W++G L L
Sbjct: 61 VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRG-GHLLFPCYQWLEGAGTLVLQ 119
Query: 110 EGTARLPGDNALDMFQKHREKELKDRQQIYCWATWKEGLPLTIAADRKDDLPPNMRFHEE 169
EGTA++ + + Q+ R++EL+ RQ++Y W + G P + +DL N+++
Sbjct: 120 EGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTA 179
Query: 170 KRLDFEWTLKAGALEMALKRVYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFS 229
K +F + EM +K + W L + +IF +++ AE + WQ+D F+
Sbjct: 180 KNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFA 239
Query: 230 YQFLNGANPMLLRRSTSLPSRLVLPSGMEELQ----AQLEKELQNGSLFEADFILLDGIP 285
QFLNG NP+L+RR LP + M L+ EL+ GSLF D +L GI
Sbjct: 240 SQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQ 299
Query: 286 ANVIRGEKQYLAAPLVMLKMEPN-GKLQPMVIQI-QPPNPSSPTPTLFLPSDPPLAWLLA 343
NVI G+ Q+ AAP+ +L P G L P+ IQ+ Q P P+SP +FLP+D WLLA
Sbjct: 300 TNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSP---IFLPTDDKWDWLLA 356
Query: 344 KSWVRNSDFQLHEIQYHLLNTHLVAEVIAVATMRCLPGLHPIFKFLIPHIRYTMEINTRA 403
K+WVRN++F HE HLL++HL+ EV +AT+R LP HP+FK
Sbjct: 357 KTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFK---------------- 400
Query: 404 RTQLISDGGIFDKAVSTGGG--GHVQLLRRAAAQLTYCSLCPPDDLADRGLLGLPGALYA 461
STG G G +L++R QL Y LC P+D+ RG+ +PG Y
Sbjct: 401 ---------------STGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYR 445
Query: 462 HDALRLWEIIARYVEGIVHLFYQRDDIVKGDPELQAWCREITEVGLCQAQDRGFPVSFQS 521
D +++W G P S ++
Sbjct: 446 DDGMQIW---------------------------------------------GIPSSLET 460
Query: 522 QSQLCHFLTMCVFTCTAQHAAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSL 581
+ L ++TM +FTC+A+HAA++ GQ D AW+PN P +M++PPPT+K T + +L
Sbjct: 461 REALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATL 520
Query: 582 PDVRQACLQMAISWHLSRRQPDMVPLGHHKEKYFSGPKPKAVLNQFRTDLEKLEKEITAR 641
P V C + W LS+ D PLG + +++F+ P+ + F++ L ++ + I R
Sbjct: 521 PPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQER 580
Query: 642 NEQLDWPYEYLKPSCIENSVTI 663
N+ L PY YL P IENSV+I
Sbjct: 581 NQGLVLPYTYLDPPLIENSVSI 602
>gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens]
Length = 1029
Score = 47.0 bits (110), Expect = 6e-05
Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 7/100 (7%)
Query: 3 RYRIRVATGAWLFSGSYNRVQLWLVGTRGEAELE------LQLRPARGEEEEFDHDVAED 56
RY++ V TG + + + V L L G RG++ L +Q++ RG+ ++F A
Sbjct: 635 RYQVDVYTGQLKHAETESEVFLCLFGERGDSGLRQLYKSNMQVKFQRGQIDKFQV-AAVS 693
Query: 57 LGLLQFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPC 96
LG LQ V LR W+C+++ V+ PG +E F C
Sbjct: 694 LGKLQKVLLRCEASDKSQYWYCEQVIVREPGTTSESIFTC 733
Score = 39.3 bits (90), Expect = 0.012
Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 8/108 (7%)
Query: 4 YRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRPA------RGEEEEFDHDVAEDL 57
Y + VATG +G+ V + + G +G+ R RG+ + F + A L
Sbjct: 43 YEVNVATGELWNAGTVANVYISIHGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLE-AVHL 101
Query: 58 GLLQFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWV-QGED 104
G L + + + WF D + ++ P E AF C+RW+ QGED
Sbjct: 102 GDLCKIVIGHDGLGPGNGWFLDDVVIKDPTTNYEYAFFCHRWLDQGED 149
>gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo
sapiens]
Length = 1029
Score = 47.0 bits (110), Expect = 6e-05
Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 7/100 (7%)
Query: 3 RYRIRVATGAWLFSGSYNRVQLWLVGTRGEAELE------LQLRPARGEEEEFDHDVAED 56
RY++ V TG + + + V L L G RG++ L +Q++ RG+ ++F A
Sbjct: 635 RYQVDVYTGQLKHAETESEVFLCLFGERGDSGLRQLYKSNMQVKFQRGQIDKFQV-AAVS 693
Query: 57 LGLLQFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPC 96
LG LQ V LR W+C+++ V+ PG +E F C
Sbjct: 694 LGKLQKVLLRCEASDKSQYWYCEQVIVREPGTTSESIFTC 733
Score = 39.3 bits (90), Expect = 0.012
Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 8/108 (7%)
Query: 4 YRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRPA------RGEEEEFDHDVAEDL 57
Y + VATG +G+ V + + G +G+ R RG+ + F + A L
Sbjct: 43 YEVNVATGELWNAGTVANVYISIHGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLE-AVHL 101
Query: 58 GLLQFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWV-QGED 104
G L + + + WF D + ++ P E AF C+RW+ QGED
Sbjct: 102 GDLCKIVIGHDGLGPGNGWFLDDVVIKDPTTNYEYAFFCHRWLDQGED 149
>gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo
sapiens]
Length = 1029
Score = 47.0 bits (110), Expect = 6e-05
Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 7/100 (7%)
Query: 3 RYRIRVATGAWLFSGSYNRVQLWLVGTRGEAELE------LQLRPARGEEEEFDHDVAED 56
RY++ V TG + + + V L L G RG++ L +Q++ RG+ ++F A
Sbjct: 635 RYQVDVYTGQLKHAETESEVFLCLFGERGDSGLRQLYKSNMQVKFQRGQIDKFQV-AAVS 693
Query: 57 LGLLQFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPC 96
LG LQ V LR W+C+++ V+ PG +E F C
Sbjct: 694 LGKLQKVLLRCEASDKSQYWYCEQVIVREPGTTSESIFTC 733
Score = 39.3 bits (90), Expect = 0.012
Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 8/108 (7%)
Query: 4 YRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRPA------RGEEEEFDHDVAEDL 57
Y + VATG +G+ V + + G +G+ R RG+ + F + A L
Sbjct: 43 YEVNVATGELWNAGTVANVYISIHGEKGDTGSRQLFRSKSSFNFLRGQTDTFFLE-AVHL 101
Query: 58 GLLQFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWV-QGED 104
G L + + + WF D + ++ P E AF C+RW+ QGED
Sbjct: 102 GDLCKIVIGHDGLGPGNGWFLDDVVIKDPTTNYEYAFFCHRWLDQGED 149
>gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo
sapiens]
Length = 1114
Score = 42.0 bits (97), Expect = 0.002
Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 8/104 (7%)
Query: 4 YRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRPARGEEEEFDHDVAE-------D 56
+ + + TG +G+ V + L GT+ + + L L+ ++ ++F+ D E D
Sbjct: 66 FSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTL-LKSSKTNSDKFERDSIEIFTVETLD 124
Query: 57 LGLLQFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWV 100
LG L VRL + WF D + V P + FPC RW+
Sbjct: 125 LGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGRWL 168
>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sapiens]
Length = 2211
Score = 42.0 bits (97), Expect = 0.002
Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 8/104 (7%)
Query: 4 YRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRPARGEEEEFDHDVAE-------D 56
+ + + TG +G+ V + L GT+ + + L L+ ++ ++F+ D E D
Sbjct: 1177 FSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTL-LKSSKTNSDKFERDSIEIFTVETLD 1235
Query: 57 LGLLQFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWV 100
LG L VRL + WF D + V P + FPC RW+
Sbjct: 1236 LGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGRWL 1279
Score = 38.9 bits (89), Expect = 0.015
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 10/109 (9%)
Query: 1 MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRPARGEEEEFDHDVAEDLGL- 59
M RY + V TG +G+ V L L G G+ E L R + F+ A++ +
Sbjct: 552 MARYHVTVCTGELEGAGTDANVYLCLFGDVGDTG-ERLLYNCRNNTDLFEKGNADEFTIE 610
Query: 60 ------LQFVRLRKHHWLVDDAWFCDRITV--QGPGACAEVAFPCYRWV 100
++ VR+R W+ DR+ V +G V FPC RW+
Sbjct: 611 SVTMRNVRRVRIRHDGKGSGSGWYLDRVLVREEGQPESDNVEFPCLRWL 659
Score = 38.9 bits (89), Expect = 0.015
Identities = 31/107 (28%), Positives = 47/107 (43%), Gaps = 6/107 (5%)
Query: 4 YRIRVATGAWLFSGSYNRVQLWLVGTR----GEAELELQLRPARGEEEEFDHDV--AEDL 57
Y ++V TG +G+ V L + G GE L+ + + E+ + D A DL
Sbjct: 1024 YEVQVVTGNVPKAGTDANVYLTIYGEEYGDTGERPLKKSDKSNKFEQGQTDTFTIYAIDL 1083
Query: 58 GLLQFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWVQGED 104
G L +R+R + WF DRI + FPC RW+ E+
Sbjct: 1084 GALTKIRIRHDNTGNRAGWFLDRIDITDMNNEITYYFPCQRWLAVEE 1130
Score = 37.4 bits (85), Expect = 0.045
Identities = 26/101 (25%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 4 YRIRVATGAWLFSGSYNRVQLWLVGTRGEAEL-ELQLRPA---RGEEEEFDHDVAEDLGL 59
Y + V TG +G+ +++ L + G RG ++ L RG + F ++A L
Sbjct: 298 YIVTVFTGDVRGAGTKSKIYLVMYGARGNKNSGKIFLEGGVFDRGRTDIFHIELAVLLSP 357
Query: 60 LQFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWV 100
L V + + V+ WFC+++ + P + FPC W+
Sbjct: 358 LSRVSVGHGNVGVNRGWFCEKVVILCPFTGIQQTFPCSNWL 398
Score = 33.5 bits (75), Expect = 0.64
Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 5/102 (4%)
Query: 3 RYRIRVATGAWLFSGSYNRVQLWLVGTRGEA-ELELQLRP---ARGEEEEFDHDVAEDLG 58
+Y ++V TG + +G+ V + + G G+ E L+ +G E+ F D A DLG
Sbjct: 173 KYEVKVYTGDVIGAGTDADVFINIFGEYGDTGERRLENEKDNFEKGAEDRFILD-APDLG 231
Query: 59 LLQFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWV 100
L + + ++ WF +I ++ G + FP RW+
Sbjct: 232 QLMKINVGHNNKGGSAGWFLSQIVIEDIGNKRKYDFPLNRWL 273
Score = 32.0 bits (71), Expect = 1.9
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 3 RYRIRVATGAWLFSGSYNRVQLWLVGTRGEA---ELELQLRPA--RGEEEEFDHDVAEDL 57
+Y + V TG +G+ V + + G G+ EL+ ++R RG + F + E L
Sbjct: 2093 KYEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLETLE-L 2151
Query: 58 GLLQFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWV 100
G L+ VRL W +++ V F C RW+
Sbjct: 2152 GELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWL 2194
>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
Length = 4753
Score = 36.2 bits (82), Expect = 0.099
Identities = 52/229 (22%), Positives = 82/229 (35%), Gaps = 40/229 (17%)
Query: 136 QQIYCWATWKE-----------------GLPLTIAADRKDDLPPNMRFHEEKR------L 172
+Q+YCWA W + L +A D P R H +
Sbjct: 109 EQLYCWAPWVQTHLHLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFV 168
Query: 173 DFEWTLKAGALEMAL-KRVYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFSYQ 231
+W+ + E+A R TL CL G + AL E V W D L
Sbjct: 169 QAQWSRQQVKEELATWLRPLTLPELQRCLG-----IVGAQVALEEAV---WLDG-LSLLP 219
Query: 232 FLNGANPMLLRRSTSLPSRLVLPSGMEELQAQL------EKELQNGSL-FEADFILLDGI 284
A+ + S+ + V P G +E ++QL EK Q S F + LD
Sbjct: 220 LALAADIPVRYESSDTDNAEVEPVGRKETRSQLDYEVPREKAFQKSSTGFSPETSFLDSQ 279
Query: 285 PANVIRGEKQYLAAPLVMLKMEPNGKLQPMVIQIQPPNPSSPTPTLFLP 333
++ E+ + L + P+ +P + + PP+ +P +F P
Sbjct: 280 VMTALKMERYLKKIHFLYLNVAPSRYFRPYSLMVVPPDKVNPEHYIFSP 328
>gi|222144247 dynein heavy chain domain 1 isoform 2 [Homo sapiens]
Length = 597
Score = 36.2 bits (82), Expect = 0.099
Identities = 52/229 (22%), Positives = 82/229 (35%), Gaps = 40/229 (17%)
Query: 136 QQIYCWATWKE-----------------GLPLTIAADRKDDLPPNMRFHEEKR------L 172
+Q+YCWA W + L +A D P R H +
Sbjct: 109 EQLYCWAPWVQTHLHLDLLGAIVQAFPPDSSLLDSASHADCCPQKRRLHHRPPCPACPFV 168
Query: 173 DFEWTLKAGALEMAL-KRVYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFSYQ 231
+W+ + E+A R TL CL G + AL E V W D L
Sbjct: 169 QAQWSRQQVKEELATWLRPLTLPELQRCLG-----IVGAQVALEEAV---WLDG-LSLLP 219
Query: 232 FLNGANPMLLRRSTSLPSRLVLPSGMEELQAQL------EKELQNGSL-FEADFILLDGI 284
A+ + S+ + V P G +E ++QL EK Q S F + LD
Sbjct: 220 LALAADIPVRYESSDTDNAEVEPVGRKETRSQLDYEVPREKAFQKSSTGFSPETSFLDSQ 279
Query: 285 PANVIRGEKQYLAAPLVMLKMEPNGKLQPMVIQIQPPNPSSPTPTLFLP 333
++ E+ + L + P+ +P + + PP+ +P +F P
Sbjct: 280 VMTALKMERYLKKIHFLYLNVAPSRYFRPYSLMVVPPDKVNPEHYIFSP 328
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 33.1 bits (74), Expect = 0.84
Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 11/79 (13%)
Query: 552 AWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMAISW----------HLSRRQ 601
A VP P PPPT +E V + ++ ++ + C Q+A S H+S +
Sbjct: 2073 AGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKEDDDVIVNKPHVSDEE 2132
Query: 602 PDMVPLGHHKEKYFSGPKP 620
+ P HH K S PKP
Sbjct: 2133 EEEPPFYHHPFK-LSEPKP 2150
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 33.1 bits (74), Expect = 0.84
Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 11/79 (13%)
Query: 552 AWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMAISW----------HLSRRQ 601
A VP P PPPT +E V + ++ ++ + C Q+A S H+S +
Sbjct: 2073 AGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKEDDDVIVNKPHVSDEE 2132
Query: 602 PDMVPLGHHKEKYFSGPKP 620
+ P HH K S PKP
Sbjct: 2133 EEEPPFYHHPFK-LSEPKP 2150
>gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo
sapiens]
Length = 512
Score = 32.0 bits (71), Expect = 1.9
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 3 RYRIRVATGAWLFSGSYNRVQLWLVGTRGEA---ELELQLRPA--RGEEEEFDHDVAEDL 57
+Y + V TG +G+ V + + G G+ EL+ ++R RG + F + E L
Sbjct: 394 KYEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLETLE-L 452
Query: 58 GLLQFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWV 100
G L+ VRL W +++ V F C RW+
Sbjct: 453 GELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWL 495
>gi|55953110 retinoblastoma protein-binding zinc finger protein
isoform c [Homo sapiens]
Length = 1481
Score = 32.0 bits (71), Expect = 1.9
Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 11/85 (12%)
Query: 254 PSGMEELQAQLEKELQNGSLFEADFILLDGIPANVIRGEKQYL-AAPLVMLKMEPNGKLQ 312
PS + L+AQ + +L GS G PA + ++P + +G+L
Sbjct: 712 PSPCKSLEAQPDPDLGPGS----------GFPAPTVESTPDVCPSSPALQTPSLSSGQLP 761
Query: 313 PMVIQIQPPNPSSPTPTLFLPSDPP 337
P++I P +P P L + + PP
Sbjct: 762 PLLIPTDPSSPPPCPPVLTVATPPP 786
>gi|20336260 retinoblastoma protein-binding zinc finger protein
isoform b [Homo sapiens]
Length = 1682
Score = 32.0 bits (71), Expect = 1.9
Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 11/85 (12%)
Query: 254 PSGMEELQAQLEKELQNGSLFEADFILLDGIPANVIRGEKQYL-AAPLVMLKMEPNGKLQ 312
PS + L+AQ + +L GS G PA + ++P + +G+L
Sbjct: 913 PSPCKSLEAQPDPDLGPGS----------GFPAPTVESTPDVCPSSPALQTPSLSSGQLP 962
Query: 313 PMVIQIQPPNPSSPTPTLFLPSDPP 337
P++I P +P P L + + PP
Sbjct: 963 PLLIPTDPSSPPPCPPVLTVATPPP 987
>gi|20336258 retinoblastoma protein-binding zinc finger protein
isoform a [Homo sapiens]
Length = 1718
Score = 32.0 bits (71), Expect = 1.9
Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 11/85 (12%)
Query: 254 PSGMEELQAQLEKELQNGSLFEADFILLDGIPANVIRGEKQYL-AAPLVMLKMEPNGKLQ 312
PS + L+AQ + +L GS G PA + ++P + +G+L
Sbjct: 913 PSPCKSLEAQPDPDLGPGS----------GFPAPTVESTPDVCPSSPALQTPSLSSGQLP 962
Query: 313 PMVIQIQPPNPSSPTPTLFLPSDPP 337
P++I P +P P L + + PP
Sbjct: 963 PLLIPTDPSSPPPCPPVLTVATPPP 987
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 31.2 bits (69), Expect = 3.2
Identities = 15/33 (45%), Positives = 21/33 (63%), Gaps = 4/33 (12%)
Query: 313 PMVIQIQPPN----PSSPTPTLFLPSDPPLAWL 341
P++ + PP+ PS PTP F+P PPLA+L
Sbjct: 192 PVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL 224
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 31.2 bits (69), Expect = 3.2
Identities = 15/33 (45%), Positives = 21/33 (63%), Gaps = 4/33 (12%)
Query: 313 PMVIQIQPPN----PSSPTPTLFLPSDPPLAWL 341
P++ + PP+ PS PTP F+P PPLA+L
Sbjct: 192 PVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL 224
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 31.2 bits (69), Expect = 3.2
Identities = 15/33 (45%), Positives = 21/33 (63%), Gaps = 4/33 (12%)
Query: 313 PMVIQIQPPN----PSSPTPTLFLPSDPPLAWL 341
P++ + PP+ PS PTP F+P PPLA+L
Sbjct: 192 PVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL 224
>gi|14150070 coiled-coil-helix-coiled-coil-helix domain containing 5
[Homo sapiens]
Length = 110
Score = 30.8 bits (68), Expect = 4.2
Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 6/46 (13%)
Query: 500 REITEVGLCQAQDRGFPVSFQSQSQLCHFLTMCVFTCTAQHAAINQ 545
RE+ + G C A P S+Q CH+L M + CT+ H I Q
Sbjct: 14 RELEQYGQCVAAK---PESWQRD---CHYLKMSIAQCTSSHPIIRQ 53
>gi|66346715 mature T-cell proliferation 1 [Homo sapiens]
Length = 107
Score = 29.6 bits (65), Expect = 9.3
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Query: 306 EPNGKLQPMVIQIQPPNPSSPTPTLFLPSDPPLAW-LLAKSWVRNSDFQLHEIQYHLL 362
E L+ V QIQ P + P+ L S PL W L + +++ +L +IQ+HL+
Sbjct: 35 EETSFLRARVQQIQVPLGDAARPSHLLTSQLPLMWQLYPEERYMDNNSRLWQIQHHLM 92
>gi|239756418 PREDICTED: hypothetical protein [Homo sapiens]
Length = 167
Score = 29.6 bits (65), Expect = 9.3
Identities = 11/30 (36%), Positives = 17/30 (56%)
Query: 307 PNGKLQPMVIQIQPPNPSSPTPTLFLPSDP 336
P+ L ++ QPPNP +P + P+DP
Sbjct: 99 PSPHLPLHILVAQPPNPDAPVQVMTFPTDP 128
>gi|239750947 PREDICTED: hypothetical protein XP_002347611 [Homo
sapiens]
Length = 167
Score = 29.6 bits (65), Expect = 9.3
Identities = 11/30 (36%), Positives = 17/30 (56%)
Query: 307 PNGKLQPMVIQIQPPNPSSPTPTLFLPSDP 336
P+ L ++ QPPNP +P + P+DP
Sbjct: 99 PSPHLPLHILVAQPPNPDAPVQVMTFPTDP 128
>gi|239745340 PREDICTED: hypothetical protein XP_002343429 [Homo
sapiens]
Length = 167
Score = 29.6 bits (65), Expect = 9.3
Identities = 11/30 (36%), Positives = 17/30 (56%)
Query: 307 PNGKLQPMVIQIQPPNPSSPTPTLFLPSDP 336
P+ L ++ QPPNP +P + P+DP
Sbjct: 99 PSPHLPLHILVAQPPNPDAPVQVMTFPTDP 128
>gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens]
Length = 1349
Score = 29.6 bits (65), Expect = 9.3
Identities = 28/112 (25%), Positives = 39/112 (34%), Gaps = 26/112 (23%)
Query: 326 PTPTLFLPSDPPLAWLLAKSWVRNSDFQLHEIQYHLLNTHLVAEVIAVATM--------- 376
P L LP P +WLL + + +Q + + L T +EV+ V T+
Sbjct: 552 PHDWLSLPVPPGPSWLLVDTLEPETAYQFSVLAQNKLGTSAFSEVVTVNTLAFPITTPEP 611
Query: 377 -------RCLPGLH----------PIFKFLIPHIRYTMEINTRARTQLISDG 411
RCL P P RY ME R +L+ DG
Sbjct: 612 LVLVTPPRCLIANRTQQGVLLSWLPPANHSFPIDRYIMEFRVAERWELLDDG 663
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,854,451
Number of Sequences: 37866
Number of extensions: 1422963
Number of successful extensions: 4004
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 3923
Number of HSP's gapped (non-prelim): 57
length of query: 663
length of database: 18,247,518
effective HSP length: 109
effective length of query: 554
effective length of database: 14,120,124
effective search space: 7822548696
effective search space used: 7822548696
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.