Search of human proteins with 154354992

Search of human proteins with 154354992

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154354992 B-box and SPRY domain containing [Homo sapiens]
         (402 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154354992 B-box and SPRY domain containing [Homo sapiens]          816   0.0  
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             125   9e-29
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   106   3e-23
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]    98   1e-20
gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo ...    96   7e-20
gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo ...    96   7e-20
gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo ...    96   7e-20
gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]    95   1e-19
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]    95   1e-19
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]     95   1e-19
gi|112421127 tripartite motif-containing 58 [Homo sapiens]             94   2e-19
gi|15208660 tripartite motif protein 21 [Homo sapiens]                 93   5e-19
gi|157743261 tripartite motif-containing 75 [Homo sapiens]             92   1e-18
gi|4557743 Mediterranean fever protein [Homo sapiens]                  91   2e-18
gi|56605981 tripartite motif-containing 72 [Homo sapiens]              88   2e-17
gi|5730009 ret finger protein [Homo sapiens]                           84   2e-16
gi|149193331 tripartite motif protein 15 [Homo sapiens]                83   5e-16
gi|22749269 ring finger protein 129 [Homo sapiens]                     82   7e-16
gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]    82   1e-15
gi|38679905 tripartite motif-containing 65 [Homo sapiens]              79   6e-15
gi|30023818 tripartite motif protein 50A [Homo sapiens]                79   9e-15
gi|31542779 tripartite motif family-like 1 [Homo sapiens]              78   2e-14
gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]       76   5e-14
gi|37622899 ring finger protein 137 [Homo sapiens]                     74   3e-13
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]     72   1e-12
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]     72   1e-12
gi|42516574 tripartite motif-containing 41 isoform 2 [Homo sapiens]    72   1e-12
gi|210147600 tripartite motif-containing 64 [Homo sapiens]             70   4e-12
gi|48255913 tripartite motif-containing 16 [Homo sapiens]              68   1e-11
gi|239755486 PREDICTED: tripartite motif-containing protein 64C-...    68   2e-11

>gi|154354992 B-box and SPRY domain containing [Homo sapiens]
          Length = 402

 Score =  816 bits (2109), Expect = 0.0
 Identities = 402/402 (100%), Positives = 402/402 (100%)

Query: 1   MSAEGAEPGPGSGSGPGPGPLCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAE 60
           MSAEGAEPGPGSGSGPGPGPLCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAE
Sbjct: 1   MSAEGAEPGPGSGSGPGPGPLCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAE 60

Query: 61  ERAEELRNKIVDQCERLQLQSAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSL 120
           ERAEELRNKIVDQCERLQLQSAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSL
Sbjct: 61  ERAEELRNKIVDQCERLQLQSAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSL 120

Query: 121 CESEEQRLLEQVHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKE 180
           CESEEQRLLEQVHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKE
Sbjct: 121 CESEEQRLLEQVHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKE 180

Query: 181 QEIFERTEEAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTEDIRIDERTVS 240
           QEIFERTEEAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTEDIRIDERTVS
Sbjct: 181 QEIFERTEEAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTEDIRIDERTVS 240

Query: 241 PFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKV 300
           PFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKV
Sbjct: 241 PFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKV 300

Query: 301 GVASGHLPRKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDL 360
           GVASGHLPRKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDL
Sbjct: 301 GVASGHLPRKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDL 360

Query: 361 QVQELLFYEPASGTVLCAHHVSFPGPLFPVFAVADQTISIVR 402
           QVQELLFYEPASGTVLCAHHVSFPGPLFPVFAVADQTISIVR
Sbjct: 361 QVQELLFYEPASGTVLCAHHVSFPGPLFPVFAVADQTISIVR 402


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  125 bits (313), Expect = 9e-29
 Identities = 111/381 (29%), Positives = 173/381 (45%), Gaps = 27/381 (7%)

Query: 16  PGPGPLCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIVDQCE 75
           P P  +CP H + L+ FCG E R +CAAC   G     HR+R  ++ AE+L+ K+    E
Sbjct: 86  PVPQGVCPAHREPLAAFCGDELRLLCAACERSGEHW-AHRVRPLQDAAEDLKAKLEKSLE 144

Query: 76  RL--QLQSAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQVH 133
            L  Q+Q A + +  AD      Q+   M  + R+ V+     +R L   EEQ+LL+++ 
Sbjct: 145 HLRKQMQDALLFQAQADETCVLWQK---MVESQRQNVLGEFERLRRLLAEEEQQLLQRLE 201

Query: 134 GEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKEQEIFERTEEAEGI 193
            EE      +     H  +    L  +   L G    L  L L+Q  ++   R ++ +  
Sbjct: 202 EEELEVLPRLREGAAHLGQQSAHLAELIAELEGRC-QLPALGLLQDIKDALRRVQDVK-- 258

Query: 194 LDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTEDIRIDERTVSPFLQLSDDRKTLT 253
           L P E   +     C R P L +      L    G  D+ +D  T +P L LS+DR+++ 
Sbjct: 259 LQPPEVVPMELRTVC-RVPGLVE-----TLRRFRG--DVTLDPDTANPELILSEDRRSVQ 310

Query: 254 FSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVASGHLPRKGSG 313
               + +A  D PERFD  P  L    F +G H W V V +  ++ +GV   ++ RK  G
Sbjct: 311 RGDLR-QALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCRENVNRKEKG 369

Query: 314 SDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRG-PAQLGVVLDLQVQELLFYEPAS 372
            +   G+  +  VF          +N     L  LR  P ++G+ LD +   L FY    
Sbjct: 370 -ELSAGNGFWILVF------LGSYYNSSERALAPLRDPPRRVGIFLDYEAGHLSFYSATD 422

Query: 373 GTVLCAH-HVSFPGPLFPVFA 392
           G++L     + F G L P+F+
Sbjct: 423 GSLLFIFPEIPFSGTLRPLFS 443


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  106 bits (265), Expect = 3e-23
 Identities = 94/378 (24%), Positives = 164/378 (43%), Gaps = 25/378 (6%)

Query: 21  LCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIVDQCERLQLQ 80
           LCP+H +ALS FC  ++  VC  CA +    R H +   ++  +E + K+    E L+ +
Sbjct: 106 LCPQHHEALSLFCYEDQEAVCLICA-ISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQK 164

Query: 81  SAAIT--KYVADVLPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQVHGEEER 138
              IT  K   +  PG+ +R V    + R+ +++    +    + E+Q LL ++  EE+ 
Sbjct: 165 LQEITRCKSSEEKKPGELKRLVE---SRRQQILREFEELHRRLDEEQQVLLSRLEEEEQD 221

Query: 139 AHQSILTQRVHWAEALQKLDTIRTGLVG--MLTHLDDLQLIQKEQEIFER--TEEAEGIL 194
             Q +     H  +  + L  +   + G  + +  + L+ ++   E  E+  T E   + 
Sbjct: 222 ILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEKCEKVKTMEVTSVS 281

Query: 195 DPQESEMLNF-NEKCTRSPLLTQLWATAVLGSLSGTEDIRIDERTVSPFLQLSDDRKTLT 253
              E    NF  +      +L QL A           D+ +D  T  P L LS+DRK++ 
Sbjct: 282 IELEKNFSNFPRQYFALRKILKQLIA-----------DVTLDPETAHPNLVLSEDRKSVK 330

Query: 254 FSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVASGHLPRKGSG 313
           F   + +   D P RF  +P  LA   F +G H W V V +   + VGV    + RKG  
Sbjct: 331 FVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGEL 390

Query: 314 SDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFYEPASG 373
           +   L    + W    ++ +   +      PL +   P ++G+ LD +   L FY     
Sbjct: 391 TP--LPETGY-WRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDR 447

Query: 374 TVLCAHHVSFPGPLFPVF 391
           + +     +F   L+P+F
Sbjct: 448 SHIYTFTDTFTEKLWPLF 465


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 91/397 (22%), Positives = 170/397 (42%), Gaps = 33/397 (8%)

Query: 21  LCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIVDQCERLQLQ 80
           LCP+H +ALS FC  ++  VC  CA +    R H +   ++  +E + K+    E L+ +
Sbjct: 106 LCPQHHEALSLFCYEDQEAVCLICA-ISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQK 164

Query: 81  SAAIT--KYVADVLPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQVHGEEER 138
              IT  K   +  PG+ +R V    + R+ +++    +    + E+Q LL ++  EE+ 
Sbjct: 165 LQEITRCKSSEEKKPGELKRLVE---SRRQQILREFEELHRRLDEEQQVLLSRLEEEEQD 221

Query: 139 AHQSILTQRVHWAEALQKLDTIRTGLVG--MLTHLDDLQLIQK--EQEIFERTEEAEGIL 194
             Q +     H  +  + L  +   + G  + +  + L+ ++   E+ I  +   +   +
Sbjct: 222 ILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEKNIPRKFGGSLSTI 281

Query: 195 DPQESE-MLNFNEKCTRSPLLTQLWATAVLGSLSGT-------------------EDIRI 234
            P++ + +L   ++  R   +  +  T+V   L                       D+ +
Sbjct: 282 CPRDHKALLGLVKEINRCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTL 341

Query: 235 DERTVSPFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQN 294
           D  T  P L LS+DRK++ F   + +   D P RF  +P  LA   F +G H W V V +
Sbjct: 342 DPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGD 401

Query: 295 SCAYKVGVASGHLPRKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQL 354
              + VGV    + RKG  +   L    + W    ++ +   +      PL +   P ++
Sbjct: 402 KTHWAVGVCRDSVSRKGELTP--LPETGY-WRVRLWNGDKYAATTTPFTPLHIKVKPKRV 458

Query: 355 GVVLDLQVQELLFYEPASGTVLCAHHVSFPGPLFPVF 391
           G+ LD +   L FY     + +     +F   L+P+F
Sbjct: 459 GIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLF 495


>gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score = 95.5 bits (236), Expect = 7e-20
 Identities = 116/432 (26%), Positives = 181/432 (41%), Gaps = 56/432 (12%)

Query: 17  GPGPLCPEHGQALS-WFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIVDQCE 75
           G G  CPEHG  ++  FC   RR VCA C  LG   RGH +  A E A  ++ K+  +C 
Sbjct: 19  GCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAH-RGHPVGLALEAAVHVQ-KLSQEC- 75

Query: 76  RLQLQSAAITK--YVADV--LPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQ 131
              L+  AI K  ++ ++  +    ++  + A +++  +  + + +R L + EE    + 
Sbjct: 76  ---LKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKF 132

Query: 132 VHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQK----EQEIFERT 187
           +    +   Q    Q     E L  ++ +   +  +    D +Q +Q     EQE+ ++ 
Sbjct: 133 IDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQM 192

Query: 188 EEAE-----------------GILDPQESEM-------LNFNEKCTRSPLLTQLWATAVL 223
              E                 G+++  ES +       L  +  C  S   +    T + 
Sbjct: 193 SLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLK 252

Query: 224 GSLSGTEDI--------RIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPE---RFDHW 272
            S S    +         +D  T+   L+LS DR T+      S     GP    RFD  
Sbjct: 253 TSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSL----GPVPVLRFDAL 308

Query: 273 PNALAATSFQNGLHAWMVNVQNSCA-YKVGVASGHLPRKGSGSDCRLGHNAFSWVFSRYD 331
              LA   F  G H W V+VQ + A + VG A   L R+G+ +  RLG N  SW   RYD
Sbjct: 309 WQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYD 368

Query: 332 QEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFYEPASG-TVLCAHHVSFPGPLFPV 390
            E+   H+GQ   L       +LGV LD +   L FY+   G + L     +F  PL+P 
Sbjct: 369 LEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPA 428

Query: 391 FAVADQTISIVR 402
             + +  ISI R
Sbjct: 429 LRLWEGAISIPR 440


>gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score = 95.5 bits (236), Expect = 7e-20
 Identities = 116/432 (26%), Positives = 181/432 (41%), Gaps = 56/432 (12%)

Query: 17  GPGPLCPEHGQALS-WFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIVDQCE 75
           G G  CPEHG  ++  FC   RR VCA C  LG   RGH +  A E A  ++ K+  +C 
Sbjct: 19  GCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAH-RGHPVGLALEAAVHVQ-KLSQEC- 75

Query: 76  RLQLQSAAITK--YVADV--LPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQ 131
              L+  AI K  ++ ++  +    ++  + A +++  +  + + +R L + EE    + 
Sbjct: 76  ---LKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKF 132

Query: 132 VHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQK----EQEIFERT 187
           +    +   Q    Q     E L  ++ +   +  +    D +Q +Q     EQE+ ++ 
Sbjct: 133 IDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQM 192

Query: 188 EEAE-----------------GILDPQESEM-------LNFNEKCTRSPLLTQLWATAVL 223
              E                 G+++  ES +       L  +  C  S   +    T + 
Sbjct: 193 SLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLK 252

Query: 224 GSLSGTEDI--------RIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPE---RFDHW 272
            S S    +         +D  T+   L+LS DR T+      S     GP    RFD  
Sbjct: 253 TSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSL----GPVPVLRFDAL 308

Query: 273 PNALAATSFQNGLHAWMVNVQNSCA-YKVGVASGHLPRKGSGSDCRLGHNAFSWVFSRYD 331
              LA   F  G H W V+VQ + A + VG A   L R+G+ +  RLG N  SW   RYD
Sbjct: 309 WQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYD 368

Query: 332 QEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFYEPASG-TVLCAHHVSFPGPLFPV 390
            E+   H+GQ   L       +LGV LD +   L FY+   G + L     +F  PL+P 
Sbjct: 369 LEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPA 428

Query: 391 FAVADQTISIVR 402
             + +  ISI R
Sbjct: 429 LRLWEGAISIPR 440


>gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score = 95.5 bits (236), Expect = 7e-20
 Identities = 116/432 (26%), Positives = 181/432 (41%), Gaps = 56/432 (12%)

Query: 17  GPGPLCPEHGQALS-WFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIVDQCE 75
           G G  CPEHG  ++  FC   RR VCA C  LG   RGH +  A E A  ++ K+  +C 
Sbjct: 19  GCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAH-RGHPVGLALEAAVHVQ-KLSQEC- 75

Query: 76  RLQLQSAAITK--YVADV--LPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQ 131
              L+  AI K  ++ ++  +    ++  + A +++  +  + + +R L + EE    + 
Sbjct: 76  ---LKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKF 132

Query: 132 VHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQK----EQEIFERT 187
           +    +   Q    Q     E L  ++ +   +  +    D +Q +Q     EQE+ ++ 
Sbjct: 133 IDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQM 192

Query: 188 EEAE-----------------GILDPQESEM-------LNFNEKCTRSPLLTQLWATAVL 223
              E                 G+++  ES +       L  +  C  S   +    T + 
Sbjct: 193 SLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLK 252

Query: 224 GSLSGTEDI--------RIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPE---RFDHW 272
            S S    +         +D  T+   L+LS DR T+      S     GP    RFD  
Sbjct: 253 TSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSL----GPVPVLRFDAL 308

Query: 273 PNALAATSFQNGLHAWMVNVQNSCA-YKVGVASGHLPRKGSGSDCRLGHNAFSWVFSRYD 331
              LA   F  G H W V+VQ + A + VG A   L R+G+ +  RLG N  SW   RYD
Sbjct: 309 WQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYD 368

Query: 332 QEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFYEPASG-TVLCAHHVSFPGPLFPV 390
            E+   H+GQ   L       +LGV LD +   L FY+   G + L     +F  PL+P 
Sbjct: 369 LEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPA 428

Query: 391 FAVADQTISIVR 402
             + +  ISI R
Sbjct: 429 LRLWEGAISIPR 440


>gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]
          Length = 450

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 102/388 (26%), Positives = 167/388 (43%), Gaps = 42/388 (10%)

Query: 21  LCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIVDQCERLQLQ 80
           LC EH + L  FC  ++ P+C  C       R HR+  AEE  +  + K+ +  E L+ Q
Sbjct: 71  LCQEHHEPLKLFCQKDQSPICVVCRE-SREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQ 129

Query: 81  SAAITKYVADVLPGKNQRAVS----MASAARELVIQRLSLVRSLCESEEQRLLEQVHGEE 136
              IT+     L  + +++++         RE ++     +      EEQRLL+ +  EE
Sbjct: 130 ---ITR--TGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEE 184

Query: 137 ERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDD------LQLIQKEQEIFERTEEA 190
           E     +        E++  LD     L  +L  L++      LQ++Q  +E   R    
Sbjct: 185 EETASRL-------RESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNV 237

Query: 191 EGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTEDIRIDERTVSPFLQL--SDD 248
             +  P+ +        C R P   ++    + G L   ED+  D  +  P+L L  S  
Sbjct: 238 S-VQCPEVAPPTRPRTVC-RVPGQIEV----LRGFL---EDVVPDATSAYPYLLLYESRQ 288

Query: 249 RKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMV--NVQNSCAYKVGVASGH 306
           R+ L  S + S  C+   +RF  +P A+  T+F +G H W V  N+     + +GV   +
Sbjct: 289 RRYLGSSPEGSGFCSK--DRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDN 346

Query: 307 LPRKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELL 366
           + RK     C    N F WV          S      P+ L+  P+ +G+ LD +  E+ 
Sbjct: 347 VSRKDRVPKC--PENGF-WVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIFLDFEAGEVS 403

Query: 367 FYEPASGTVLCAH-HVSFPGPLFPVFAV 393
           FY  + G+ L  +   +FPGPL P F +
Sbjct: 404 FYSVSDGSHLHTYSQATFPGPLQPFFCL 431


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 102/388 (26%), Positives = 167/388 (43%), Gaps = 42/388 (10%)

Query: 21  LCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIVDQCERLQLQ 80
           LC EH + L  FC  ++ P+C  C       R HR+  AEE  +  + K+ +  E L+ Q
Sbjct: 98  LCQEHHEPLKLFCQKDQSPICVVCRE-SREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQ 156

Query: 81  SAAITKYVADVLPGKNQRAVS----MASAARELVIQRLSLVRSLCESEEQRLLEQVHGEE 136
              IT+     L  + +++++         RE ++     +      EEQRLL+ +  EE
Sbjct: 157 ---ITR--TGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEE 211

Query: 137 ERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDD------LQLIQKEQEIFERTEEA 190
           E     +        E++  LD     L  +L  L++      LQ++Q  +E   R    
Sbjct: 212 EETASRL-------RESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNV 264

Query: 191 EGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTEDIRIDERTVSPFLQL--SDD 248
             +  P+ +        C R P   ++    + G L   ED+  D  +  P+L L  S  
Sbjct: 265 S-VQCPEVAPPTRPRTVC-RVPGQIEV----LRGFL---EDVVPDATSAYPYLLLYESRQ 315

Query: 249 RKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMV--NVQNSCAYKVGVASGH 306
           R+ L  S + S  C+   +RF  +P A+  T+F +G H W V  N+     + +GV   +
Sbjct: 316 RRYLGSSPEGSGFCSK--DRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDN 373

Query: 307 LPRKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELL 366
           + RK     C    N F WV          S      P+ L+  P+ +G+ LD +  E+ 
Sbjct: 374 VSRKDRVPKC--PENGF-WVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIFLDFEAGEVS 430

Query: 367 FYEPASGTVLCAH-HVSFPGPLFPVFAV 393
           FY  + G+ L  +   +FPGPL P F +
Sbjct: 431 FYSVSDGSHLHTYSQATFPGPLQPFFCL 458


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 102/388 (26%), Positives = 167/388 (43%), Gaps = 42/388 (10%)

Query: 21  LCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIVDQCERLQLQ 80
           LC EH + L  FC  ++ P+C  C       R HR+  AEE  +  + K+ +  E L+ Q
Sbjct: 98  LCQEHHEPLKLFCQKDQSPICVVCRE-SREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQ 156

Query: 81  SAAITKYVADVLPGKNQRAVS----MASAARELVIQRLSLVRSLCESEEQRLLEQVHGEE 136
              IT+     L  + +++++         RE ++     +      EEQRLL+ +  EE
Sbjct: 157 ---ITR--TGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEE 211

Query: 137 ERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDD------LQLIQKEQEIFERTEEA 190
           E     +        E++  LD     L  +L  L++      LQ++Q  +E   R    
Sbjct: 212 EETASRL-------RESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNV 264

Query: 191 EGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTEDIRIDERTVSPFLQL--SDD 248
             +  P+ +        C R P   ++    + G L   ED+  D  +  P+L L  S  
Sbjct: 265 S-VQCPEVAPPTRPRTVC-RVPGQIEV----LRGFL---EDVVPDATSAYPYLLLYESRQ 315

Query: 249 RKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMV--NVQNSCAYKVGVASGH 306
           R+ L  S + S  C+   +RF  +P A+  T+F +G H W V  N+     + +GV   +
Sbjct: 316 RRYLGSSPEGSGFCSK--DRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDN 373

Query: 307 LPRKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELL 366
           + RK     C    N F WV          S      P+ L+  P+ +G+ LD +  E+ 
Sbjct: 374 VSRKDRVPKC--PENGF-WVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIFLDFEAGEVS 430

Query: 367 FYEPASGTVLCAH-HVSFPGPLFPVFAV 393
           FY  + G+ L  +   +FPGPL P F +
Sbjct: 431 FYSVSDGSHLHTYSQATFPGPLQPFFCL 458


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 104/408 (25%), Positives = 157/408 (38%), Gaps = 60/408 (14%)

Query: 11  GSGSGPGPGPLCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKI 70
           G G+GPG    C  HG+ LS FC  +   +C  C   G   R HR    +E A   + K 
Sbjct: 86  GLGAGPG-ARRCARHGEDLSRFCEEDEAALCWVCDA-GPEHRTHRTAPLQEAAGSYQVK- 142

Query: 71  VDQCERLQLQSAAITKYVADVLPGKNQRAVSMASAARELVIQR------LSLVRSLCESE 124
                 LQ+    + K + D L  +            ++ +QR          R     E
Sbjct: 143 ------LQMALELMRKELEDALTQEANVGKKTVIWKEKVEMQRQRFRLEFEKHRGFLAQE 196

Query: 125 EQRLLEQVHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKEQEIF 184
           EQR L ++  EE                 LQ+L   ++ LV     L +L       E+ 
Sbjct: 197 EQRQLRRLEAEERAT--------------LQRLRESKSRLVQQSKALKELA-----DELQ 237

Query: 185 ERTEE-AEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGT-------------- 229
           ER +  A G+L+     +       +RS  +T+L A  +   L                 
Sbjct: 238 ERCQRPALGLLEGVRGVL-------SRSKAVTRLEAENIPMELKTACCIPGRRELLRKFQ 290

Query: 230 EDIRIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWM 289
            D+++D  T  P L L+ D +++    +  +   + PERFD WP  L   SF +G H W 
Sbjct: 291 VDVKLDPATAHPSLLLTADLRSVQ-DGEPWRDVPNNPERFDTWPCILGLQSFSSGRHYWE 349

Query: 290 VNVQNSCAYKVGVASGHLPRKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLR 349
           V V     + +GV    LPRKG  +          W+    +     S +    PL  L 
Sbjct: 350 VLVGEGAEWGLGVCQDTLPRKGETTPSPENGVWALWLLKGNEYMVLASPS---VPLLQLE 406

Query: 350 GPAQLGVVLDLQVQELLFYEPASGTVLCAHHVSFPGPLFPVFAVADQT 397
            P  +G+ LD +  E+ FY    G+ +   +  F G L P F + D T
Sbjct: 407 SPRCIGIFLDYEAGEISFYNVTDGSYIYTFNQLFSGLLRPYFFICDAT 454


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score = 92.8 bits (229), Expect = 5e-19
 Identities = 95/382 (24%), Positives = 155/382 (40%), Gaps = 31/382 (8%)

Query: 19  GPLCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIVDQCERLQ 78
           G  C  HG+ L  FC  + + +C  CA    + R H +   EE A+E + K+      L+
Sbjct: 89  GERCAVHGERLHLFCEKDGKALCWVCAQ-SRKHRDHAMVPLEEAAQEYQEKLQVALGELR 147

Query: 79  LQSAAITKYVADVL----PGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQVHG 134
            +     K   ++       K       +    E V Q+  LV      EEQR L+++  
Sbjct: 148 RKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVE-----EEQRQLQELEK 202

Query: 135 EEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKEQEIFERTEEAEGIL 194
           +E    + +  +    A+  Q L  + + L     H   L+L+Q+   + ER        
Sbjct: 203 DEREQLRILGEKEAKLAQQSQALQELISEL-DRRCHSSALELLQEVIIVLER-------- 253

Query: 195 DPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGT--EDIRIDERTVSPFLQLSDDRKTL 252
               SE  N  +    SP L  +     L  +  T    I +D  T +P+L LS+DR+ +
Sbjct: 254 ----SESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQV 309

Query: 253 TFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVASGHLPRKGS 312
                + ++     ERFD +P  L A  F +G H W V+V    A+ +GV    + RKG 
Sbjct: 310 RLGDTQ-QSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKG- 367

Query: 313 GSDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFYE--P 370
                L   +  W    ++++   +      PL L   P Q+G+ LD +   + FY    
Sbjct: 368 --HFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITD 425

Query: 371 ASGTVLCAHHVSFPGPLFPVFA 392
               +      +F GPL P F+
Sbjct: 426 HGSLIYSFSECAFTGPLRPFFS 447


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 87/373 (23%), Positives = 150/373 (40%), Gaps = 16/373 (4%)

Query: 21  LCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIVDQCERLQLQ 80
           LC +H Q LS FC  +   +C  C       +GH +R  E+ A   R +     + L+ Q
Sbjct: 96  LCEKHNQPLSVFCKEDLMVLCPLCTQPPDH-QGHHVRPIEKAAIHYRKRFCSYIQPLKKQ 154

Query: 81  SAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQVHGEEERAH 140
            A + K ++     K      M    R+ +      +    + E+Q +L ++  EEE+ +
Sbjct: 155 LADLQKLIS-TQSKKPLELREMVENQRQELSSEFEHLNQFLDREQQAVLSRL-AEEEKDN 212

Query: 141 QSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKEQEIFERTEEAEGILDPQESE 200
           Q  L+  +            +   V  L+ L +L+L+ + +  +E   E+     P    
Sbjct: 213 QQKLSANITAFSNYSATLKSQLSKVVELSELSELELLSQIKIFYESENESS----PSIFS 268

Query: 201 MLNFNEKCTRSPLLTQLWATAVLGSLSGTEDIRIDERTVSPFLQLSDDRKTLTFSTKKSK 260
           +    + C+  P  + L        +    +I +D  T  P L +S+D+K + F+ +K K
Sbjct: 269 IHLKRDGCSFPPQYSALQRIIKKFKV----EIILDPETAHPNLIVSEDKKRVRFTKRKQK 324

Query: 261 ACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVASGHLPRKGSGSDCRLGH 320
                P+RF   P  L    F +G H W + V +   + +G+    LP K          
Sbjct: 325 V-PGFPKRFTVKPVVLGFPYFHSGRHFWEIEVGDKSEWAIGICKDSLPTKARRPS---SA 380

Query: 321 NAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFYEPASGTVLCAHH 380
               W     D  +  +      PL L      +G+ LD ++ E+ FY  A  + +C   
Sbjct: 381 QQECWRIELQDDGYH-APGAFPTPLLLEVKARAIGIFLDYEMGEISFYNMAEKSHICTFT 439

Query: 381 VSFPGPLFPVFAV 393
            +F GPL P F V
Sbjct: 440 DTFTGPLRPYFYV 452


>gi|4557743 Mediterranean fever protein [Homo sapiens]
          Length = 781

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 107/413 (25%), Positives = 175/413 (42%), Gaps = 49/413 (11%)

Query: 10  PGSGSGPGPGPLCPEH-GQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRN 68
           PGS S P P P C  H  Q    FC     P+C  C+ L    +GHR+R  EE A E + 
Sbjct: 364 PGSLS-PQPLPQCKRHLKQVQLLFCEDHDEPICLICS-LSQEHQGHRVRPIEEVALEHKK 421

Query: 69  KIVDQCERLQLQSAAITKYVADVLPGKNQRAVS---MASAARELVIQRLSLVRSLCESEE 125
           KI  Q E L+     + K   +      ++AVS      A ++ V ++L  V    E +E
Sbjct: 422 KIQKQLEHLK----KLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQE 477

Query: 126 QRLLE------QVHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQK 179
              +       Q+ G+  +A+ + ++Q +   +AL        G +       + +L+Q 
Sbjct: 478 HFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDAL-------IGELEAKECQSEWELLQD 530

Query: 180 EQEIFERTEEA---EGILDPQE-----------SEMLNFNEKCTRSPLLTQLW---ATAV 222
             +I  R +     E    PQE           SE +  + K     L +++       +
Sbjct: 531 IGDILHRAKTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPEL 590

Query: 223 LGSLSGTEDIRIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQ 282
           +G+ +   ++ +D  T  P L  SDD K++    K  +   DGP+RFD     L + SF 
Sbjct: 591 IGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWER-LPDGPQRFDSCIIVLGSPSFL 649

Query: 283 NGLHAWMVNVQNSCAYKVGVASGHLPRKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQH 342
           +G   W V V +  A+ +G     + RKG+ +      N +  V    + E++ S     
Sbjct: 650 SGRRYWEVEVGDKTAWILGACKTSISRKGNMT--LSPENGYWVVIMMKENEYQAS---SV 704

Query: 343 EPLGLL--RGPAQLGVVLDLQVQELLFYE-PASGTVLCAHHVSFPGPLFPVFA 392
            P  LL    P ++G+ +D +V  + FY   A   +      SF GPL P+F+
Sbjct: 705 PPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFS 757


>gi|56605981 tripartite motif-containing 72 [Homo sapiens]
          Length = 477

 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 89/382 (23%), Positives = 152/382 (39%), Gaps = 22/382 (5%)

Query: 22  CPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIVDQCERLQLQS 81
           C EH   LS +C  +R  VC  CA LG   RGHR+  A E    L+ ++  Q  +LQLQ 
Sbjct: 86  CEEHLDPLSIYCEQDRALVCGVCASLGSH-RGHRLLPAAEAHARLKTQLPQQ--KLQLQE 142

Query: 82  AAITKYVA-DVLPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRL---LEQVHGEEE 137
           A + K  +  VL  +           R  V ++L  +R    + E  L    E+V GE  
Sbjct: 143 ACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMRVFLAALEGSLDCEAERVRGEAG 202

Query: 138 RAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKEQEIFERTEEAEGILDPQ 197
            A +  L     + E L++++ +    +  +      + + K   +  R ++   + +  
Sbjct: 203 VALRRELGSLNSYLEQLRQMEKV----LEEVADKPQTEFLMKYCLVTSRLQKI--LAESP 256

Query: 198 ESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTEDIRIDERTVSPFLQLSDDRKTLTFSTK 257
               L+            Q+W       +   E++  D  +  P L +S   + +  S +
Sbjct: 257 PPARLDIQLPIISDDFKFQVWRKMFRALMPALEELTFDPSSAHPSLVVSSSGRRVECSEQ 316

Query: 258 KSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVASGHLPRKGSGSDCR 317
           K+    + P +FD     +A      G H W V+V +   + +GV +   PR+G      
Sbjct: 317 KAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVDVGDKPRWALGVIAAEAPRRGR---LH 373

Query: 318 LGHNAFSWVFSRYDQEFRFSHNGQHEPLGLL---RGPAQLGVVLDLQVQELLFYEPASGT 374
              +   W+    + +   +H    EP  L    R P ++G+ L      L FY+ +   
Sbjct: 374 AVPSQGLWLLGLREGKILEAHVEAKEPRALRSPERRPTRIGLYLSFGDGVLSFYDASDAD 433

Query: 375 VLC---AHHVSFPGPLFPVFAV 393
            L    A H   P P++P F V
Sbjct: 434 ALVPLFAFHERLPRPVYPFFDV 455


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 101/423 (23%), Positives = 171/423 (40%), Gaps = 70/423 (16%)

Query: 9   GPGSGSGPGPGPLCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRN 68
           GPG   G     +C +H + L  +C  ++ P+C  C       RGH +   EE  E  + 
Sbjct: 88  GPGGEMG-----VCEKHREPLKLYCEEDQMPICVVC-DRSREHRGHSVLPLEEAVEGFKE 141

Query: 69  KIVDQCERLQLQSAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRL 128
           +I +Q + L        K V D+   K +R      A  EL+        SL + E +++
Sbjct: 142 QIQNQLDHL--------KRVKDL---KKRRRAQGEQARAELL--------SLTQMEREKI 182

Query: 129 LEQVHGEEERAHQSILTQRVHWAEALQKLD-TIRTGLVGMLT-------HLDDL--QLIQ 178
           +     E E+ + S+          L++LD  I   + G +T       HL  L  QL +
Sbjct: 183 V----WEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEE 238

Query: 179 KEQE--------IFERTEEAEGILDPQ--------ESEMLNFNEKCTRSPLLTQLWATAV 222
           K+Q+        I +    AE I  P+        + ++  F +KC       + +   +
Sbjct: 239 KQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKM 298

Query: 223 LGSLSGTEDIR----------IDERTVSPFLQLSDDRKTLTFSTKKSKACADGPERFDHW 272
              +   +++R          +D  T  P L LSD+ + + +S  +     D PERF+ +
Sbjct: 299 QSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDL-PDNPERFNLF 357

Query: 273 PNALAATSFQNGLHAWMVNVQNSCAYKVGVASGHLPRKGSGSDCRLGHNAFSWVFSRYDQ 332
           P  L +  F  G H W V V +   + +GV    + RKG  +      N F  V   Y +
Sbjct: 358 PCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSA--PQNGFWAVSLWYGK 415

Query: 333 EFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFYEPASGT-VLCAHHVSFPGPLFPVF 391
           E+ ++       L L     ++G+ LD    E+ FY            H +F GP+ P F
Sbjct: 416 EY-WALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYF 474

Query: 392 AVA 394
           +++
Sbjct: 475 SLS 477


>gi|149193331 tripartite motif protein 15 [Homo sapiens]
          Length = 465

 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 91/389 (23%), Positives = 163/389 (41%), Gaps = 20/389 (5%)

Query: 15  GPGPGPLCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIVDQC 74
           GP     C EHG+ + +FC ++   +C  C   G   + H +   +E  +  R+++  + 
Sbjct: 76  GPLGETYCEEHGEKIYFFCENDAEFLCVFCRE-GPTHQAHTVGFLDEAIQPYRDRLRSRL 134

Query: 75  ERLQLQSAAITKYVAD------VLPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRL 128
           E L  +   I            VL  + +        A E + Q L   R L  +  + L
Sbjct: 135 EALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQELEQQRCLLLARLREL 194

Query: 129 LEQVHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKEQEIFERTE 188
            +Q+  E +     +  +       +++L+         L  L D+++ Q   E+ +   
Sbjct: 195 EQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASEL--LQDVRVNQSRCEM-KTFV 251

Query: 189 EAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLS-GTEDIRIDERTVSPFLQLSD 247
             E I      ++ +F+ K    P + ++++  +   L   +  I +D +T S  L LS+
Sbjct: 252 SPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLDPQTASRSLVLSE 311

Query: 248 DRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQ--NSCAYKVGVASG 305
           DRK++ + T++ K+  D P RFD  P  L    F +G H W V++Q  +     VGVA  
Sbjct: 312 DRKSVRY-TRQKKSLPDSPLRFDGLPAVLGFPGFSSGRHRWQVDLQLGDGGGCTVGVAGE 370

Query: 306 HLPRKGSGSDCRLGHNAFSW-VFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQE 364
            + RKG   +  L      W V   + Q +  +  G   PL  +  P  + V LD +  +
Sbjct: 371 GVRRKG---EMGLSAEDGVWAVIISHQQCWASTSPGTDLPLSEI--PRGVRVALDYEAGQ 425

Query: 365 LLFYEPASGTVLCAHHVSFPGPLFPVFAV 393
           +  +   +   +     SF G +FP FAV
Sbjct: 426 VTLHNAQTQEPIFTFTASFSGKVFPFFAV 454


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 87/382 (22%), Positives = 152/382 (39%), Gaps = 36/382 (9%)

Query: 21  LCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIVDQCERLQLQ 80
           +C +H Q L+ FC  +   +C  C+    + + H I   ++ A   R  +    E L+  
Sbjct: 96  MCEKHNQFLTLFCVKDLEILCTQCS-FSTKHQKHYICPIKKAASYHREILEGSLEPLRNN 154

Query: 81  SAAITKYVADVLPG-KNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQVHGEEERA 139
              + K +  +L G K+          RE +      +R   ++E++ +L Q+  EE   
Sbjct: 155 IERVEKVI--ILQGSKSVELKKKVEYKREEINSEFEQIRLFLQNEQEMILRQIQDEE--- 209

Query: 140 HQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKEQEIFERTEEAEGILDPQES 199
                         +  L  +   LV +  ++  L+ + +E E        E +   +  
Sbjct: 210 --------------MNILAKLNENLVELSDYVSTLKHLLREVEGKSVQSNLELLTQAKSM 255

Query: 200 EMLNFNEKCTR--SPLLTQLWATAVLGSLSGTE--------DIRIDERTVSPFLQLSDDR 249
                N KC    S  LT+ +  ++    SG +        D+ +D  T  P L +S+DR
Sbjct: 256 HHKYQNLKCPELFSFRLTK-YGFSLPPQYSGLDRIIKPFQVDVILDLNTAHPQLLVSEDR 314

Query: 250 KTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVASGHLPR 309
           K + +  KK   C D P RF   P  L +  F +G H W V V N   + +GV    L R
Sbjct: 315 KAVRYERKKRNICYD-PRRFYVCPAVLGSQRFSSGRHYWEVEVGNKPKWILGVCQDCLLR 373

Query: 310 KGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFYE 369
                   LG     W   RY +    +   +   L  +  P+++G+ LD ++ +L FY 
Sbjct: 374 NWQDQPSVLGG---FWAIGRYMKSGYVASGPKTTQLLPVVKPSKIGIFLDYELGDLSFYN 430

Query: 370 PASGTVLCAHHVSFPGPLFPVF 391
               ++L   +  F   ++P F
Sbjct: 431 MNDRSILYTFNDCFTEAVWPYF 452


>gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]
          Length = 630

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 104/429 (24%), Positives = 162/429 (37%), Gaps = 65/429 (15%)

Query: 8   PGPGSGSGPGPGPLCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELR 67
           P PG GS      +CP+H +AL  FC  +   +C  C       + H +   EE  +E +
Sbjct: 213 PTPGRGSRVTDQGICPKHQEALKLFCEVDEEAICVVCRESRSH-KQHSVVPLEEVVQEYK 271

Query: 68  NKIVDQCERLQLQSAAITKYVAD----VLPGKNQRAVSMASAARE-------LVIQRLSL 116
            K+    E L+    A+ K  A     V   K+Q    +A+ A E       L  ++  L
Sbjct: 272 AKLQGHVEPLRKHLEAVQKMKAKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGL 331

Query: 117 VRSLCESEEQRLLEQVHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQL 176
            R L E  E +L          A Q+    R+  AEA ++            +    L+L
Sbjct: 332 ERRLREMHEAQLGRAGAAASRLAEQAAQLSRL-LAEAQER------------SQQGGLRL 378

Query: 177 IQKEQEIFERTEEAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLS------GTE 230
           +Q  +E F R EE +  L P E   +   + C   P        A++  +S         
Sbjct: 379 LQDIKETFNRCEEVQ--LQPPE---VWSPDPC--QPHSHDFLTDAIVRKMSRMFCQAARV 431

Query: 231 DIRIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMV 290
           D+ +D  T  P L LS DR+ +  + ++ +  AD P+RF      L A  F++G H W V
Sbjct: 432 DLTLDPDTAHPALMLSPDRRGVRLAERRQEV-ADHPKRFSADCCVLGAQGFRSGRHYWEV 490

Query: 291 NVQNSCAYKVGVA---SGHLPRKGSGSDCRLGHNAFS----------------------W 325
            V     + VG A   + H  + G G       +A S                      W
Sbjct: 491 EVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRRLHLPQQPLLQREVW 550

Query: 326 VFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFYEPASGTVLCAHHVSFPG 385
                 + ++   + +   L     P + GV LD +   L FY   +   +     +F G
Sbjct: 551 CVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAETLAHVHTFSAAFLG 610

Query: 386 P-LFPVFAV 393
             +FP F V
Sbjct: 611 ERVFPFFRV 619


>gi|38679905 tripartite motif-containing 65 [Homo sapiens]
          Length = 517

 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 115/442 (26%), Positives = 169/442 (38%), Gaps = 89/442 (20%)

Query: 7   EPGPGSGSGPGPGPLCPEHGQALSWFCGSERRPVCAACAGLGGRCRGH------------ 54
           +PGP  G GP P   CP HG+ L  FC +E R VC+ C      CR H            
Sbjct: 80  DPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVCT--VRECRLHERALLDAERLKR 137

Query: 55  --RIRRAEERAEELRNKIVDQCERLQLQSAAITK---YVADVLPGKNQRAVSMASAAREL 109
             ++R + E  ++   +   Q   L+ QS+ I      +A  + GK       +S  + L
Sbjct: 138 EAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILASWVSGK------FSSLLQAL 191

Query: 110 VIQRLSLVRSLCESEEQRLLEQVHGEEERAHQSI------------LTQRVHWAEALQKL 157
            IQ  + +RS+ E  + + L Q   EE+R    +            L ++V     LQ+ 
Sbjct: 192 EIQHTTALRSI-EVAKTQALAQARDEEQRLRVHLEAVARHGCRIRELLEQVDEQTFLQES 250

Query: 158 DTIR-TGLVGMLTHL--DDLQLIQKEQEIFER----------------------TEEAEG 192
             ++  G +G LT L  D+ Q +   +++  R                        EA G
Sbjct: 251 QLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGLLLEEGSHPGAPAKPVDLAPVEAPG 310

Query: 193 ILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTEDIRIDERTVSPFLQLSDDRKTL 252
            L P  S         T  PL  +LW            ++  D  + +    LS  R+  
Sbjct: 311 PLAPVPS---------TVCPLRRKLW--------QNYRNLTFDPVSANRHFYLS--RQDQ 351

Query: 253 TFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVASGHLPRKGS 312
                +      GP  F+ W     A SFQ G H W V   +  +  +GV+   LPR   
Sbjct: 352 QVKHCRQSRGPGGPGSFELW-QVQCAQSFQAGHHYWEVRASDH-SVTLGVSYPQLPRCRL 409

Query: 313 GSDC-RLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFY--E 369
           G     +G    SW     +   +  HNG+ + L  + G   LG+ LDL    L FY  E
Sbjct: 410 GPHTDNIGRGPCSWGLCVQEDSLQAWHNGEAQRLPGVSG-RLLGMDLDLASGCLTFYSLE 468

Query: 370 PASGTVLCAHHVSFPGPLFPVF 391
           P +   L   H  F  PL PVF
Sbjct: 469 PQT-QPLYTFHALFNQPLTPVF 489


>gi|30023818 tripartite motif protein 50A [Homo sapiens]
          Length = 487

 Score = 78.6 bits (192), Expect = 9e-15
 Identities = 82/385 (21%), Positives = 151/385 (39%), Gaps = 22/385 (5%)

Query: 16  PG-PGP-LCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIVDQ 73
           PG P P +C  H   LS FC  ++  +C  C GL G  + H +         ++ ++   
Sbjct: 81  PGDPEPKVCVHHRNPLSLFCEKDQELICGLC-GLLGSHQHHPVTPVSTVYSRMKEELAAL 139

Query: 74  CERLQLQSAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQVH 133
              L+ +   + + +A ++  +  R V+ +     ++ +    +  L + E+ R LE + 
Sbjct: 140 ISELKQEQKKVDELIAKLVNNRT-RIVNESDVFSWVIRREFQELHHLVDEEKARCLEGIG 198

Query: 134 GEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKEQEIFERTE----- 188
           G   R   + L  ++  A+  ++       ++    + D  + I+K   +  R E     
Sbjct: 199 GHT-RGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHKFIRKFHSMASRAEMPQAR 257

Query: 189 EAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTEDIRIDERTVSPFLQLSDD 248
             EG   P     ++F     ++ +   +W       L   E +++D  T  P L+LS  
Sbjct: 258 PLEGAFSP-----ISFKPGLHQADIKLTVWKRLFRKVLPAPEPLKLDPATAHPLLELSKG 312

Query: 249 RKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVASGHLP 308
              +       +  A  PERFD+    LA+  F  G H W V V +   +++GV  G   
Sbjct: 313 NTVVQCGLLAQRR-ASQPERFDYSTCVLASRGFSCGRHYWEVVVGSKSDWRLGVIKGTAS 371

Query: 309 RKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFY 368
           RKG             W+    +     +      PL +   P ++G+ L  +  EL F+
Sbjct: 372 RKGK---LNRSPEHGVWLIGLKEGRVYEAFACPRVPLPVAGHPHRIGLYLHYEQGELTFF 428

Query: 369 E---PASGTVLCAHHVSFPGPLFPV 390
           +   P     L      F G L+P+
Sbjct: 429 DADRPDDLRPLYTFQADFQGKLYPI 453


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 80/355 (22%), Positives = 142/355 (40%), Gaps = 47/355 (13%)

Query: 54  HRIRRAEERAEELRNKIVDQCERLQLQSAAITKYVADVLPGKNQRAV---SMASAARELV 110
           +R+  + E  E  R K+ +    L+++     K    VL  + +R           +++V
Sbjct: 123 NRVHLSSEAEEHHREKLQEILNLLRVRR----KEAQAVLTHEKERVKLCQEETKTCKQVV 178

Query: 111 IQRLSLVRSLCESEEQRLLEQVHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTH 170
           +     +    + EEQ  L+ +  EE+   + +    +   + ++ L         M+  
Sbjct: 179 VSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSK-------MIAQ 231

Query: 171 LDDLQLIQKEQEIFERTEEAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTE 230
           ++       +   FE  EE  G L+  E  +L   E  T    L ++     +     TE
Sbjct: 232 IES----SSQSSAFESLEEVRGALERSEPLLLQCPEATTTELSLCRITGMKEMLRKFSTE 287

Query: 231 DIRIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMV 290
            I +D  T + +L LS+D K++ +   + +   D PERFD     L    F +G H W V
Sbjct: 288 -ITLDPATANAYLVLSEDLKSVKYGGSRQQL-PDNPERFDQSATVLGTQIFTSGRHYWEV 345

Query: 291 NVQNSCAYKVGVASGHLPRKG----------SGSDCRLGHNAFSWVFSRYDQEFRFSHNG 340
            V N   ++VG+    + RKG          S    ++G +   WV S           G
Sbjct: 346 EVGNKTEWEVGICKDSVSRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPL--------KG 397

Query: 341 QH--EPLGLLRGPAQLGVVLDLQVQELLFYEPASGTVLCAH-HVSFPGPLFPVFA 392
           QH  EP+       ++GV LD +   + FY     +++ +    SF   L P+F+
Sbjct: 398 QHVREPV------CKVGVFLDYESGHIAFYNGTDESLIYSFPQASFQEALRPIFS 446


>gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]
          Length = 526

 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 56/191 (29%), Positives = 90/191 (47%), Gaps = 11/191 (5%)

Query: 205 NEKCTRSPLLTQL-WATAVLGSLSGTEDIRIDERTVSPFLQLSDDRKTLTFSTKKSKACA 263
           NE  ++  LL +L W  A L ++    D+ +D  T  P L L +D K++     + K   
Sbjct: 281 NEFSSKERLLEELKWKKATLHAV----DVTLDPDTAHPHLFLYEDSKSVRLEDSRQKL-P 335

Query: 264 DGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVASGHLPRKGSGSDCRLGHNAF 323
           +  ERFD WP  L   +F +G H W V V +   + +GV   ++ +K  G D     N F
Sbjct: 336 EKTERFDSWPCVLGRETFTSGRHYWEVEVGDRTDWAIGVCRENVMKK--GFDPMTPENGF 393

Query: 324 SWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFYEPASGT-VLCAHHVS 382
            W    Y   + ++      PL L   P ++G+ LD +  ++ FY    G+ +    +V+
Sbjct: 394 -WAVELYGNGY-WALTPLRTPLPLAGPPRRVGIFLDYESGDISFYNMNDGSDIYTFSNVT 451

Query: 383 FPGPLFPVFAV 393
           F GPL P F +
Sbjct: 452 FSGPLRPFFCL 462


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 100/409 (24%), Positives = 163/409 (39%), Gaps = 60/409 (14%)

Query: 10  PGSGSGPGPGPLCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNK 69
           PG G     G LC  HG+ L  FC  +   +C AC+        H +   E+ A E + +
Sbjct: 89  PGMGL---KGDLCERHGEKLKMFCKEDVLIMCEACSQ-SPEHEAHSVVPMEDVAWEYKWE 144

Query: 70  IVDQCERLQLQSAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRLL 129
           + +  E L+ +     K       G+ +R    A+   ++  ++ S+V      + QRLL
Sbjct: 145 LHEALEHLKKEQEEAWKLEV----GERKRT---ATWKIQVETRKQSIVWEF--EKYQRLL 195

Query: 130 EQVH------GEEERAHQSILTQRVHWAEALQKLDTIRTGLVG-------MLTHLDDLQ- 175
           E+        G E  A  + L +    AE +QKL+   + L+        M+  L +   
Sbjct: 196 EKKQPPHRQLGAEVAAALASLQREA--AETMQKLELNHSELIQQSQVLWRMIAELKERSQ 253

Query: 176 -----LIQKEQEIFERTEEAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTE 230
                ++Q  QE+  R++     L   E   L     C    L   L   A         
Sbjct: 254 RPVRWMLQDIQEVLNRSKSWS--LQQPEPISLELKTDCRVLGLREILKTYAA-------- 303

Query: 231 DIRIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMV 290
           D+R+D  T    L +S+DRK + +     K   D PERF  +   L +    +G H W V
Sbjct: 304 DVRLDPDTAYSRLIVSEDRKRVHYGDTNQKL-PDNPERFYRYNIVLGSQCISSGRHYWEV 362

Query: 291 NVQNSCAYKVGVASGHLPRKGSGSDCRLGHNAFSWVFS-RYDQEFRFSHNGQHEPLGLLR 349
            V +   + +GV   ++ RK       L  +   WV   R   E+R +   ++  L L  
Sbjct: 363 EVGDRSEWGLGVCKQNVDRK---EVVYLSPHYGFWVIRLRKGNEYR-AGTDEYPILSLPV 418

Query: 350 GPAQLGVVLDLQVQELLFYEPASGTVLCAHHV------SFPGPLFPVFA 392
            P ++G+ +D +  ++ FY        C  H+       FPG L P F+
Sbjct: 419 PPRRVGIFVDYEAHDISFYNVTD----CGSHIFTFPRYPFPGRLLPYFS 463


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 89/399 (22%), Positives = 165/399 (41%), Gaps = 37/399 (9%)

Query: 17  GPGP-----LCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIV 71
           GPG      LC +HG+ L  FC  + + +C  C       RGH     EE A+E + K  
Sbjct: 87  GPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCER-SQEHRGHHTFLVEEVAQEYQEKFQ 145

Query: 72  DQCERLQLQSAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQ 131
           +  ++L+ +     K  A +   K      M    R  +    + +R++ +  EQR L++
Sbjct: 146 ESLKKLKNEEQEAEKLTAFIREKKTSWKNQM-EPERCRIQTEFNQLRNILDRVEQRELKK 204

Query: 132 VHGEEERAHQSILTQR---VHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKEQEIFERTE 188
           +  EE++  + I       VH  ++L++L       +  L        ++  Q++ + TE
Sbjct: 205 LEQEEKKGLRIIEEAENDLVHQTQSLREL-------ISDLERRCQGSTMELLQDVSDVTE 257

Query: 189 EAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTE----DIRIDERTVSPFLQ 244
            +E     +   +        R+P L ++    V   L+  +    D+ ++  T +  L 
Sbjct: 258 RSEFWTLRKPEALPTKLRSMFRAPDLKRM--LRVCRELTDVQSYWVDVTLNPHTANLNLV 315

Query: 245 LSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVAS 304
           L+ +R+ + F   K    +   + +D   + L +  F +G H W V+V    A+ +GV S
Sbjct: 316 LAKNRRQVRFVGAKVSGPSCLEKHYDC--SVLGSQHFSSGKHYWEVDVAKKTAWILGVCS 373

Query: 305 GHLPRKGSGSDCRLGHNAFS--------WVFS-RYDQEFR-FSHNGQHEPLGLLRGPAQL 354
             L    S +     H+A+S        WV   +++ E+R +  +     L +   P ++
Sbjct: 374 NSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVPPRRV 433

Query: 355 GVVLDLQVQELLFYEPASG--TVLCAHHVSFPGPLFPVF 391
           GV LD +   + FY   +    +       FP  L P F
Sbjct: 434 GVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 472


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 89/399 (22%), Positives = 165/399 (41%), Gaps = 37/399 (9%)

Query: 17  GPGP-----LCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIV 71
           GPG      LC +HG+ L  FC  + + +C  C       RGH     EE A+E + K  
Sbjct: 115 GPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCER-SQEHRGHHTFLVEEVAQEYQEKFQ 173

Query: 72  DQCERLQLQSAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQ 131
           +  ++L+ +     K  A +   K      M    R  +    + +R++ +  EQR L++
Sbjct: 174 ESLKKLKNEEQEAEKLTAFIREKKTSWKNQM-EPERCRIQTEFNQLRNILDRVEQRELKK 232

Query: 132 VHGEEERAHQSILTQR---VHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKEQEIFERTE 188
           +  EE++  + I       VH  ++L++L       +  L        ++  Q++ + TE
Sbjct: 233 LEQEEKKGLRIIEEAENDLVHQTQSLREL-------ISDLERRCQGSTMELLQDVSDVTE 285

Query: 189 EAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTE----DIRIDERTVSPFLQ 244
            +E     +   +        R+P L ++    V   L+  +    D+ ++  T +  L 
Sbjct: 286 RSEFWTLRKPEALPTKLRSMFRAPDLKRM--LRVCRELTDVQSYWVDVTLNPHTANLNLV 343

Query: 245 LSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVAS 304
           L+ +R+ + F   K    +   + +D   + L +  F +G H W V+V    A+ +GV S
Sbjct: 344 LAKNRRQVRFVGAKVSGPSCLEKHYDC--SVLGSQHFSSGKHYWEVDVAKKTAWILGVCS 401

Query: 305 GHLPRKGSGSDCRLGHNAFS--------WVFS-RYDQEFR-FSHNGQHEPLGLLRGPAQL 354
             L    S +     H+A+S        WV   +++ E+R +  +     L +   P ++
Sbjct: 402 NSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVPPRRV 461

Query: 355 GVVLDLQVQELLFYEPASG--TVLCAHHVSFPGPLFPVF 391
           GV LD +   + FY   +    +       FP  L P F
Sbjct: 462 GVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 500


>gi|42516574 tripartite motif-containing 41 isoform 2 [Homo sapiens]
          Length = 518

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 78/298 (26%), Positives = 121/298 (40%), Gaps = 39/298 (13%)

Query: 8   PGPGSGSGPGPGPLCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELR 67
           P PG GS      +CP+H +AL  FC  +   +C  C       + H +   EE  +E +
Sbjct: 213 PTPGRGSRVTDQGICPKHQEALKLFCEVDEEAICVVCRESRSH-KQHSVVPLEEVVQEYK 271

Query: 68  NKIVDQCERLQLQSAAITKYVAD----VLPGKNQRAVSMASAARE-------LVIQRLSL 116
            K+    E L+    A+ K  A     V   K+Q    +A+ A E       L  ++  L
Sbjct: 272 AKLQGHVEPLRKHLEAVQKMKAKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGL 331

Query: 117 VRSLCESEEQRLLEQVHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQL 176
            R L E  E +L          A Q+    R+  AEA ++            +    L+L
Sbjct: 332 ERRLREMHEAQLGRAGAAASRLAEQAAQLSRL-LAEAQER------------SQQGGLRL 378

Query: 177 IQKEQEIFERTEEAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLS------GTE 230
           +Q  +E F R EE +  L P E   +   + C   P        A++  +S         
Sbjct: 379 LQDIKETFNRCEEVQ--LQPPE---VWSPDPC--QPHSHDFLTDAIVRKMSRMFCQAARV 431

Query: 231 DIRIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAW 288
           D+ +D  T  P L LS DR+ +  + ++ +  AD P+RF      L A  F++G H W
Sbjct: 432 DLTLDPDTAHPALMLSPDRRGVRLAERRQEV-ADHPKRFSADCCVLGAQGFRSGRHYW 488


>gi|210147600 tripartite motif-containing 64 [Homo sapiens]
          Length = 449

 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 84/378 (22%), Positives = 153/378 (40%), Gaps = 31/378 (8%)

Query: 21  LCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIVDQCERLQLQ 80
           +C  H +    FC +++R +C  C+        H        AEE R K++ + + L   
Sbjct: 91  ICVLHEETKELFCEADKRLLCGPCSE-SPEHMAHSHSPIGWAAEECREKLIKEMDYLW-- 147

Query: 81  SAAITKYVADVLPGKNQRAVSM---ASAARELVIQRLSLVRSLCESEEQRLLEQVHGEEE 137
              I +   + L  + +   S+    S  + ++  +   +    + EEQR L+ +  E E
Sbjct: 148 --EINQETRNNLNQETRTFHSLKDYVSVRKRIITIQYQKMPIFLDEEEQRHLQALEREAE 205

Query: 138 RAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKEQEIFERTEEAEGILDPQ 197
              Q +   +V   + L+++  +   L     H+ D++L+Q  + +  RT+ A+     Q
Sbjct: 206 ELFQQLQDSQVRMTQHLERMKDMYREL-WETCHVPDVELLQDVRNVSARTDLAQ----MQ 260

Query: 198 ESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTE-DIRIDERTVSPFLQLSDDRKTLTFST 256
           + + +N        P LT    T VL  L+    D  +    +  ++ LS+D + + F  
Sbjct: 261 KPQPVN--------PELTSWCITGVLDMLNNFRVDSALSTEMIPCYISLSEDVRYVIFGD 312

Query: 257 KKSKACAD--GPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVASGHLPRKGSGS 314
               A  D  G + F  W     A +F +G H W V+V  S  + +GV      R    +
Sbjct: 313 DHLSAPTDPQGVDSFAVW----GAQAFTSGKHYWEVDVTLSSNWILGVCQD--SRTADAN 366

Query: 315 DCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFYEPASGT 374
                   F  + S+    +  S N       + R   Q+GV LD     + F++ + G+
Sbjct: 367 FVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQRPLGQVGVFLDYDNGSVSFFDVSKGS 426

Query: 375 VLCAH-HVSFPGPLFPVF 391
           ++      SF  PL P F
Sbjct: 427 LIYGFPPSSFSSPLRPFF 444


>gi|48255913 tripartite motif-containing 16 [Homo sapiens]
          Length = 564

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 99/425 (23%), Positives = 155/425 (36%), Gaps = 76/425 (17%)

Query: 22  CPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAE----ERAEELRNKIVDQCERL 77
           CP H   LS FC  +++ +C  C        GH I   +    ++  EL+   +D   +L
Sbjct: 131 CPAHHSPLSAFCCPDQQCICQDCCQ---EHSGHTIVSLDAARRDKEAELQCTQLDLERKL 187

Query: 78  QLQSAAIT----------------KYVADVLPGKNQRAVSMASAARELVIQR-----LSL 116
           +L   AI+                K VA++  G+   AV  A A   L ++      LS 
Sbjct: 188 KLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQ 247

Query: 117 VRSLCESEEQRLLEQVHGEEERAHQSILTQRVHWAEAL-------------------QKL 157
              +    E R  E    ++E    + ++  V + E                      KL
Sbjct: 248 ANGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKL 307

Query: 158 DTIRTGLVGMLTHL--------DDLQLIQKEQEIFERTEEAEGILDPQESEMLNFNEKCT 209
             IR  +     HL          LQ   KE+E   RT+ +  +   Q     +  E  T
Sbjct: 308 SGIRKVITESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVV---QRKYWTSKPEPST 364

Query: 210 RSPLLTQLWATAVLGSLSGTEDIRIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPERF 269
           R   L   +            DI  D  T   +L+L ++ + +T +T       D P RF
Sbjct: 365 REQFLQYAY------------DITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRF 412

Query: 270 DHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVASGHLPRKGSGSDCRLGHNAFSWVFSR 329
            HW   L+  S     + + V +  +  Y VG+    + RKG   +  +  N FSW    
Sbjct: 413 LHWRQVLSQQSLYLHRYYFEVEIFGAGTY-VGLTCKGIDRKGEERNSCISGNNFSWSLQW 471

Query: 330 YDQEFRFSHNGQHEPLGLLRGP-AQLGVVLDLQVQELLFYEPASGTVLCAHHVS--FPGP 386
             +EF   ++    P  L  GP  +LGV +D     L FY     T+   H  +  F  P
Sbjct: 472 NGKEFTAWYSDMETP--LKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEP 529

Query: 387 LFPVF 391
           ++  F
Sbjct: 530 VYAAF 534


>gi|239755486 PREDICTED: tripartite motif-containing protein
           64C-like isoform 2 [Homo sapiens]
          Length = 447

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 86/379 (22%), Positives = 150/379 (39%), Gaps = 35/379 (9%)

Query: 21  LCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELR-NKIVDQCERLQL 79
           +C  H +    FC +++R +C  C+        H        AEE R  K++ + + L  
Sbjct: 91  ICVLHEETKELFCEADKRLLCGPCSE-SPEHMAHSHSPIGWAAEECRVQKLIKEMDYLW- 148

Query: 80  QSAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQVHGEEERA 139
               I +   + L  +  +  S+    R  ++ R   +    + EEQR L+ +  E +  
Sbjct: 149 ---KINQETQNNLNQETSKFCSLVEDKRNRIVYRYQKMHIFLDEEEQRHLQALEREAKEL 205

Query: 140 HQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKEQEIFERTEEAEGILDPQES 199
            Q +   +V   + L+ +  +   L     H+ D++L+Q    I  RT+ A+ +  PQ  
Sbjct: 206 FQQLQDSQVRMTQHLEGMKDMYRELWETY-HMPDVELLQDVGNISARTDLAQ-MPKPQPV 263

Query: 200 EMLNFNEKCTRSPLLTQLWATAVLGSLSGTE-DIRIDERTVSPFLQLSDDRKTLTFSTKK 258
                      +P LT    T VL  L+    D  +       ++ LS+D + + F    
Sbjct: 264 -----------NPELTSWCITGVLDMLNNFRVDNALSTEMTPCYISLSEDVRRVIFGDDH 312

Query: 259 SKACAD--GPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVASGHLPRKGSGSDC 316
             A  D  G E F  W     A +F +G H W V+V +S  + +GV      R    +D 
Sbjct: 313 RSAPMDPQGVESFAVW----CAQAFTSGKHYWEVDVTHSSNWILGVC-----RDSRTADT 363

Query: 317 RL---GHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFYEPASG 373
            +       F  + S+    +  S N       + R    +GV LD     + F++ + G
Sbjct: 364 NIVIDSDKTFFSISSKTSNHYSLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDVSKG 423

Query: 374 TVLCAH-HVSFPGPLFPVF 391
           +++      SF  PL P F
Sbjct: 424 SLIYGFPPSSFSSPLRPFF 442


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,012,610
Number of Sequences: 37866
Number of extensions: 825276
Number of successful extensions: 4593
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 115
Number of HSP's successfully gapped in prelim test: 126
Number of HSP's that attempted gapping in prelim test: 3995
Number of HSP's gapped (non-prelim): 527
length of query: 402
length of database: 18,247,518
effective HSP length: 105
effective length of query: 297
effective length of database: 14,271,588
effective search space: 4238661636
effective search space used: 4238661636
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.