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Search of human proteins with 153792768
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153792768 claudin 6 [Homo sapiens]
(220 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153792768 claudin 6 [Homo sapiens] 444 e-125
gi|11141861 claudin 9 [Homo sapiens] 321 4e-88
gi|4502877 claudin 4 [Homo sapiens] 284 5e-77
gi|4502875 claudin 3 [Homo sapiens] 270 5e-73
gi|195947374 claudin 5 [Homo sapiens] 240 6e-64
gi|195947372 claudin 5 [Homo sapiens] 240 6e-64
gi|10863887 claudin 1 [Homo sapiens] 199 1e-51
gi|153792186 claudin 7 [Homo sapiens] 198 3e-51
gi|40788011 claudin 8 [Homo sapiens] 197 8e-51
gi|6912316 claudin 17 [Homo sapiens] 195 2e-50
gi|183979973 claudin 19 isoform a [Homo sapiens] 186 2e-47
gi|183979975 claudin 19 isoform b [Homo sapiens] 184 4e-47
gi|225703142 claudin 14 [Homo sapiens] 177 6e-45
gi|21536294 claudin 14 [Homo sapiens] 177 6e-45
gi|225703138 claudin 14 [Homo sapiens] 177 6e-45
gi|6912314 claudin 14 [Homo sapiens] 177 6e-45
gi|225703140 claudin 14 [Homo sapiens] 177 6e-45
gi|9966781 claudin 2 [Homo sapiens] 172 2e-43
gi|47716519 claudin 20 [Homo sapiens] 132 2e-31
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] 131 4e-31
gi|5921465 claudin 10 isoform b [Homo sapiens] 131 4e-31
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] 130 1e-30
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] 130 1e-30
gi|7656981 claudin 15 [Homo sapiens] 127 7e-30
gi|162417973 claudin 22 [Homo sapiens] 125 4e-29
gi|7705961 claudin 18 isoform 1 [Homo sapiens] 123 1e-28
gi|50345279 claudin 18 isoform 2 [Homo sapiens] 122 2e-28
gi|157820127 claudin-like [Homo sapiens] 110 9e-25
gi|33598916 claudin 10 isoform a [Homo sapiens] 109 2e-24
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] 94 1e-19
>gi|153792768 claudin 6 [Homo sapiens]
Length = 220
Score = 444 bits (1142), Expect = e-125
Identities = 220/220 (100%), Positives = 220/220 (100%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG
Sbjct: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120
QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120
Query: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180
SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL
Sbjct: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180
Query: 181 LCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV 220
LCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV
Sbjct: 181 LCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV 220
>gi|11141861 claudin 9 [Homo sapiens]
Length = 217
Score = 321 bits (822), Expect = 4e-88
Identities = 156/220 (70%), Positives = 185/220 (84%), Gaps = 3/220 (1%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MAS G+++LG+ L +LGW+ LVSCALP+WKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG
Sbjct: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120
QMQCKVYDSLLALPQDLQAARALCVIALL+AL GLLV + GA+CTTCVE++ +KAR+VLT
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120
Query: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180
+G++ +++G+L LIPVCWTAHAII+DFYNPLVAEA KRELGASLYLGWAA+ LL+LGGGL
Sbjct: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180
Query: 181 LCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV 220
LCCTCP + P YS + + G S ++YV
Sbjct: 181 LCCTCPPPQVERPRGPRLGYSIPSRS---GASGLDKRDYV 217
>gi|4502877 claudin 4 [Homo sapiens]
Length = 209
Score = 284 bits (726), Expect = 5e-77
Identities = 127/206 (61%), Positives = 170/206 (82%), Gaps = 3/206 (1%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MAS G+Q++G+ L +LGW+ ++ CALPMW+VTAFIG++IV +Q +WEGLWM+CVVQSTG
Sbjct: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120
QMQCKVYDSLLALPQDLQAARAL +I+++VA G+L+ + G KCT C+E++ +KA+ ++
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
Query: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180
+G+VF+++G++ ++PV WTAH II+DFYNPLVA QKRE+GASLY+GWAASGLLLLGGGL
Sbjct: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
Query: 181 LCCTCPSGGSQGPSHYMARYSTSAPA 206
LCC CP + Y A+YS + A
Sbjct: 181 LCCNCP---PRTDKPYSAKYSAARSA 203
>gi|4502875 claudin 3 [Homo sapiens]
Length = 220
Score = 270 bits (691), Expect = 5e-73
Identities = 130/221 (58%), Positives = 172/221 (77%), Gaps = 5/221 (2%)
Query: 3 SAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQM 62
S G++I G L +LGW+ +V CALPMW+V+AFIG++I+ +Q +WEGLWM+CVVQSTGQM
Sbjct: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61
Query: 63 QCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLTSG 122
QCKVYDSLLALPQDLQAARAL V+A+L+A FGLLV L GA+CT CV++ +KA++ + +G
Sbjct: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121
Query: 123 IVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGLLC 182
++F+++ +LTL+PV W+A+ IIRDFYNP+V EAQKRE+GA LY+GWAA+ L LLGG LLC
Sbjct: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181
Query: 183 CTCPSGGSQGPSH---YMARYSTSAPAISRGPSEYPTKNYV 220
C+CP + + Y A ST P S G + Y K+YV
Sbjct: 182 CSCPPREKKYTATKVVYSAPRST-GPGASLG-TGYDRKDYV 220
>gi|195947374 claudin 5 [Homo sapiens]
Length = 303
Score = 240 bits (613), Expect = 6e-64
Identities = 116/220 (52%), Positives = 158/220 (71%), Gaps = 2/220 (0%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
M SA ++ILG+VL L+GW +++C LPMW+VTAF+ ++IV AQ W+GLWMSCVVQSTG
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120
MQCKVYDS+LAL ++QAARAL V A+L+A L V LAGA+CTTCV +KAR+ LT
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
Query: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180
G++++ G+L L+P+CW A+ ++R+FY+P V +QK ELGA+LY+GWAA+ LL++GG L
Sbjct: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
Query: 181 LCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV 220
LCC + + +Y SAP +Y KNYV
Sbjct: 266 LCCGAWVCTGRPDLSFPVKY--SAPRRPTATGDYDKKNYV 303
>gi|195947372 claudin 5 [Homo sapiens]
Length = 303
Score = 240 bits (613), Expect = 6e-64
Identities = 116/220 (52%), Positives = 158/220 (71%), Gaps = 2/220 (0%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
M SA ++ILG+VL L+GW +++C LPMW+VTAF+ ++IV AQ W+GLWMSCVVQSTG
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120
MQCKVYDS+LAL ++QAARAL V A+L+A L V LAGA+CTTCV +KAR+ LT
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
Query: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180
G++++ G+L L+P+CW A+ ++R+FY+P V +QK ELGA+LY+GWAA+ LL++GG L
Sbjct: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
Query: 181 LCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV 220
LCC + + +Y SAP +Y KNYV
Sbjct: 266 LCCGAWVCTGRPDLSFPVKY--SAPRRPTATGDYDKKNYV 303
>gi|10863887 claudin 1 [Homo sapiens]
Length = 211
Score = 199 bits (507), Expect = 1e-51
Identities = 96/223 (43%), Positives = 142/223 (63%), Gaps = 15/223 (6%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MA+AG+Q+LG +L LGW+ +VS ALP W++ ++ G++IV AQ ++EGLWMSCV QSTG
Sbjct: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKD-SKARLVL 119
Q+QCKV+DSLL L LQA RAL V+ +L+ + + V G KC C+E+ + K R+ +
Sbjct: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
Query: 120 TSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGG 179
G +F+++G+ L+ W + I+++FY+P+ + E G +L+ GWAA+ L LLGG
Sbjct: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
Query: 180 LLCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPT--KNYV 220
LLCC+CP R +TS P P P+ K+YV
Sbjct: 181 LLCCSCP------------RKTTSYPTPRPYPKPAPSSGKDYV 211
>gi|153792186 claudin 7 [Homo sapiens]
Length = 211
Score = 198 bits (504), Expect = 3e-51
Identities = 96/220 (43%), Positives = 143/220 (65%), Gaps = 17/220 (7%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSC-ALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQST 59
MA++G+Q+LG + LLGWV GLV+C A+P W+++++ G++I+ AQ +++GLWM CV QST
Sbjct: 1 MANSGLQLLGFSMALLGWV-GLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQST 59
Query: 60 GQMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTC-VEEKDSKARLV 118
G M CK+YDS+LAL LQA RAL V++L++ + V G KCT C ++K KAR+
Sbjct: 60 GMMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIA 119
Query: 119 LTSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGG 178
+ GI+F+++G+ L+ W H I+ DFYNPL+ K E G ++++GWA S L++LGG
Sbjct: 120 MGGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGG 179
Query: 179 GLLCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKN 218
LL C+CP G++ + Y R P YP N
Sbjct: 180 ALLSCSCP--GNESKAGY------------RVPRSYPKSN 205
>gi|40788011 claudin 8 [Homo sapiens]
Length = 225
Score = 197 bits (500), Expect = 8e-51
Identities = 101/225 (44%), Positives = 145/225 (64%), Gaps = 5/225 (2%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MA+ ++I G+ L +G V + +P W+V+AFI N+IVV + WEGLWM+CV Q+
Sbjct: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDS-KARLVL 119
+MQCK+YDSLLAL DLQAAR L A +++ ++ + G KCT C + + KA ++L
Sbjct: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
Query: 120 TSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGG 179
T+GI+F+I+G++ LIPV W A+AIIRDFYN +V AQKRELG +LYLGW + +L++GG
Sbjct: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
Query: 180 LLCCT-CPSGGSQGPSHYMARYSTSAPAISRG---PSEYPTKNYV 220
L CC C + S + + + T+ + G PS Y YV
Sbjct: 181 LFCCVFCCNEKSSSYRYSIPSHRTTQKSYHTGKKSPSVYSRSQYV 225
>gi|6912316 claudin 17 [Homo sapiens]
Length = 224
Score = 195 bits (496), Expect = 2e-50
Identities = 93/186 (50%), Positives = 133/186 (71%), Gaps = 1/186 (0%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MA +QI G+VL LG V L + LP W+V+AF+G++I+V + +WEGLWM+C+ Q+
Sbjct: 1 MAFYPLQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARV 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKD-SKARLVL 119
++QCK Y SLLALP L+ ARAL +A+ ++L LL+ + G K C + +KA L+
Sbjct: 61 RLQCKFYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLG 120
Query: 120 TSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGG 179
TSG++F+++G+ LIPV WTA+ IIRDFYNP + QKRELGA+L+LGWA++ +L +GGG
Sbjct: 121 TSGVLFILTGIFVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIGGG 180
Query: 180 LLCCTC 185
LLC C
Sbjct: 181 LLCGFC 186
>gi|183979973 claudin 19 isoform a [Homo sapiens]
Length = 224
Score = 186 bits (471), Expect = 2e-47
Identities = 92/221 (41%), Positives = 140/221 (63%), Gaps = 10/221 (4%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MA++G+Q+LG L L GWV + S ALP WK +++ G++I+ A ++EGLWMSC QSTG
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKD-SKARLVL 119
Q+QCK+YDSLLAL +Q+ARAL V+A+L+ +++ + G KCT + +K R+ +
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 120 TSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGG 179
G +F+++G+ TL V W A + ++F+NP + E G +L++GWA++GL +LGG
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 180 LLCCTC--PSGGSQGPSHYMARYSTSA-------PAISRGP 211
LCCTC P + P Y S +A PA ++GP
Sbjct: 181 FLCCTCPEPERPNSSPQPYRPGPSAAAREPVVKLPASAKGP 221
>gi|183979975 claudin 19 isoform b [Homo sapiens]
Length = 211
Score = 184 bits (468), Expect = 4e-47
Identities = 89/207 (42%), Positives = 133/207 (64%), Gaps = 1/207 (0%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MA++G+Q+LG L L GWV + S ALP WK +++ G++I+ A ++EGLWMSC QSTG
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKD-SKARLVL 119
Q+QCK+YDSLLAL +Q+ARAL V+A+L+ +++ + G KCT + +K R+ +
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 120 TSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGG 179
G +F+++G+ TL V W A + ++F+NP + E G +L++GWA++GL +LGG
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 180 LLCCTCPSGGSQGPSHYMARYSTSAPA 206
LCCTCP S R SA A
Sbjct: 181 FLCCTCPEPERPNSSPQPYRPGPSAAA 207
>gi|225703142 claudin 14 [Homo sapiens]
Length = 239
Score = 177 bits (449), Expect = 6e-45
Identities = 89/210 (42%), Positives = 130/210 (61%), Gaps = 4/210 (1%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MAS +Q+LG +L+ LG V L++ LP W+ TA +G +I+ A +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120
QC++Y SLLALPQDLQAARAL VI+ L++ + G KCT C + +K +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180
G +F+++G+L ++ V WT + ++++FYNPL+ K E+G +LYLG+ +S L L+GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCCTC----PSGGSQGPSHYMARYSTSAPA 206
LC +C P Q P + +APA
Sbjct: 181 LCLSCQDEAPYRPYQAPPRATTTTANTAPA 210
>gi|21536294 claudin 14 [Homo sapiens]
Length = 239
Score = 177 bits (449), Expect = 6e-45
Identities = 89/210 (42%), Positives = 130/210 (61%), Gaps = 4/210 (1%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MAS +Q+LG +L+ LG V L++ LP W+ TA +G +I+ A +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120
QC++Y SLLALPQDLQAARAL VI+ L++ + G KCT C + +K +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180
G +F+++G+L ++ V WT + ++++FYNPL+ K E+G +LYLG+ +S L L+GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCCTC----PSGGSQGPSHYMARYSTSAPA 206
LC +C P Q P + +APA
Sbjct: 181 LCLSCQDEAPYRPYQAPPRATTTTANTAPA 210
>gi|225703138 claudin 14 [Homo sapiens]
Length = 239
Score = 177 bits (449), Expect = 6e-45
Identities = 89/210 (42%), Positives = 130/210 (61%), Gaps = 4/210 (1%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MAS +Q+LG +L+ LG V L++ LP W+ TA +G +I+ A +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120
QC++Y SLLALPQDLQAARAL VI+ L++ + G KCT C + +K +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180
G +F+++G+L ++ V WT + ++++FYNPL+ K E+G +LYLG+ +S L L+GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCCTC----PSGGSQGPSHYMARYSTSAPA 206
LC +C P Q P + +APA
Sbjct: 181 LCLSCQDEAPYRPYQAPPRATTTTANTAPA 210
>gi|6912314 claudin 14 [Homo sapiens]
Length = 239
Score = 177 bits (449), Expect = 6e-45
Identities = 89/210 (42%), Positives = 130/210 (61%), Gaps = 4/210 (1%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MAS +Q+LG +L+ LG V L++ LP W+ TA +G +I+ A +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120
QC++Y SLLALPQDLQAARAL VI+ L++ + G KCT C + +K +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180
G +F+++G+L ++ V WT + ++++FYNPL+ K E+G +LYLG+ +S L L+GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCCTC----PSGGSQGPSHYMARYSTSAPA 206
LC +C P Q P + +APA
Sbjct: 181 LCLSCQDEAPYRPYQAPPRATTTTANTAPA 210
>gi|225703140 claudin 14 [Homo sapiens]
Length = 239
Score = 177 bits (449), Expect = 6e-45
Identities = 89/210 (42%), Positives = 130/210 (61%), Gaps = 4/210 (1%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MAS +Q+LG +L+ LG V L++ LP W+ TA +G +I+ A +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120
QC++Y SLLALPQDLQAARAL VI+ L++ + G KCT C + +K +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180
G +F+++G+L ++ V WT + ++++FYNPL+ K E+G +LYLG+ +S L L+GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCCTC----PSGGSQGPSHYMARYSTSAPA 206
LC +C P Q P + +APA
Sbjct: 181 LCLSCQDEAPYRPYQAPPRATTTTANTAPA 210
>gi|9966781 claudin 2 [Homo sapiens]
Length = 230
Score = 172 bits (436), Expect = 2e-43
Identities = 84/211 (39%), Positives = 127/211 (60%), Gaps = 2/211 (0%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MAS G+Q++G +L LLG + LV+ LP WK ++++G SIV A +GLWM C STG
Sbjct: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120
QC +Y +LL LP D+QAA+A+ V + ++ ++ + G +CT +E +K R+ +
Sbjct: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120
Query: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180
G+ F++ G+L IPV W H I+RDFY+PLV ++ K E+G +LYLG +S L+ G +
Sbjct: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180
Query: 181 LCCTCPSGGSQGPSHYMARYSTSAPAISRGP 211
LC +C S + S+Y Y A P
Sbjct: 181 LCFSCSS--QRNRSNYYDAYQAQPLATRSSP 209
>gi|47716519 claudin 20 [Homo sapiens]
Length = 219
Score = 132 bits (333), Expect = 2e-31
Identities = 66/185 (35%), Positives = 105/185 (56%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MASAG+Q+L +L L G L + LP WKV + ++I+ A V GLWM C STG
Sbjct: 1 MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120
C + S+L+LP +QAARA V+A +++ G+ G KCT ++++K+
Sbjct: 61 MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120
Query: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180
G+ F+ +G+ +LI W II +F + V E+ K E G ++Y+G+ ++ LL + G +
Sbjct: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180
Query: 181 LCCTC 185
C +C
Sbjct: 181 FCTSC 185
>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 131 bits (330), Expect = 4e-31
Identities = 79/212 (37%), Positives = 118/212 (55%), Gaps = 7/212 (3%)
Query: 6 MQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCK 65
MQ +G++L+LLGW+ +++ LP WK N + + GLW +CV+Q MQCK
Sbjct: 9 MQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTM---GLWQTCVIQEEVGMQCK 65
Query: 66 VYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVE-EKDSKARLVLTSGIV 124
+DS LALP +L+ +R L ++ + GLLV G C E ++D K RL++ GI+
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
Query: 125 FVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKR-ELGASLYLGWAASGLLLLGGGLL-C 182
SG+ L+PV W AH +++F++ V + R E G +L+LGW A LLLGG LL C
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
Query: 183 CTCPSGGSQGPSHY-MARYSTSAPAISRGPSE 213
C S HY +A+ T P + G ++
Sbjct: 186 AACSSHAPLALGHYAVAQMQTQCPYLEDGTAD 217
>gi|5921465 claudin 10 isoform b [Homo sapiens]
Length = 228
Score = 131 bits (330), Expect = 4e-31
Identities = 72/184 (39%), Positives = 107/184 (58%), Gaps = 6/184 (3%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPM--WKVTAFIGNSIVVAQVVWEGLWMSCVVQS 58
MAS +I+ ++++ GWV LVS LP WKV+ G I A W LW +CV S
Sbjct: 1 MASTASEIIAFMVSISGWV--LVSSTLPTDYWKVSTIDGTVITTA-TYWANLWKACVTDS 57
Query: 59 TGQMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLV 118
TG CK + S+LAL +QA R L + A+ + FG + L G KCT +KA++
Sbjct: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIA 117
Query: 119 LTSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGG 178
+GIVF++SG+ ++ A+ I +F++PL E QK ELGA+L++GWA + L ++GG
Sbjct: 118 CLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGG 176
Query: 179 GLLC 182
+ C
Sbjct: 177 VIFC 180
>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 130 bits (326), Expect = 1e-30
Identities = 78/212 (36%), Positives = 117/212 (55%), Gaps = 7/212 (3%)
Query: 6 MQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCK 65
MQ +G++L+ LGW+ +++ LP WK N + + GLW +CV+Q MQCK
Sbjct: 9 MQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTM---GLWQTCVIQEEVGMQCK 65
Query: 66 VYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVE-EKDSKARLVLTSGIV 124
+DS LALP +L+ +R L ++ + GLLV G C E ++D K RL++ GI+
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
Query: 125 FVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKR-ELGASLYLGWAASGLLLLGGGLL-C 182
SG+ L+PV W AH +++F++ V + R E G +L+LGW A LLLGG LL C
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
Query: 183 CTCPSGGSQGPSHY-MARYSTSAPAISRGPSE 213
C S HY +A+ T P + G ++
Sbjct: 186 AACSSHAPLALGHYAVAQMQTQCPYLEDGTAD 217
>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 130 bits (326), Expect = 1e-30
Identities = 78/212 (36%), Positives = 117/212 (55%), Gaps = 7/212 (3%)
Query: 6 MQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCK 65
MQ +G++L+ LGW+ +++ LP WK N + + GLW +CV+Q MQCK
Sbjct: 9 MQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTM---GLWQTCVIQEEVGMQCK 65
Query: 66 VYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVE-EKDSKARLVLTSGIV 124
+DS LALP +L+ +R L ++ + GLLV G C E ++D K RL++ GI+
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
Query: 125 FVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKR-ELGASLYLGWAASGLLLLGGGLL-C 182
SG+ L+PV W AH +++F++ V + R E G +L+LGW A LLLGG LL C
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
Query: 183 CTCPSGGSQGPSHY-MARYSTSAPAISRGPSE 213
C S HY +A+ T P + G ++
Sbjct: 186 AACSSHAPLALGHYAVAQMQTQCPYLEDGTAD 217
>gi|7656981 claudin 15 [Homo sapiens]
Length = 228
Score = 127 bits (319), Expect = 7e-30
Identities = 71/195 (36%), Positives = 107/195 (54%), Gaps = 15/195 (7%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MA+ G+ +LGV L W+V+ GN ++ ++E LW SC S G
Sbjct: 12 MATVGLLMLGVTLPN------------SYWRVSTVHGN-VITTNTIFENLWFSCATDSLG 58
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVE-EKDSKARLVL 119
C + S+LAL +QA RAL + A+L+ GLL+ +AG +CT E KA+L
Sbjct: 59 VYNCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAA 118
Query: 120 TSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGG 179
T+G + +++G+ ++ + W A I RDF++PL K ELG +LYLGW+AS + +LGG
Sbjct: 119 TAGALHILAGICGMVAISWYAFNITRDFFDPLY-PGTKYELGPALYLGWSASLISILGGL 177
Query: 180 LLCCTCPSGGSQGPS 194
LC C G + P+
Sbjct: 178 CLCSACCCGSDEDPA 192
>gi|162417973 claudin 22 [Homo sapiens]
Length = 220
Score = 125 bits (313), Expect = 4e-29
Identities = 77/193 (39%), Positives = 106/193 (54%), Gaps = 6/193 (3%)
Query: 7 QILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKV 66
Q+ GV L+LLGWV ++ LP WK N + + GLW +CV+Q MQCK
Sbjct: 10 QLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTM---GLWQTCVIQEEVGMQCKD 66
Query: 67 YDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVE-EKDSKARLVLTSGIVF 125
+DS LALP +L+ +R L ++ + GLLV G C E ++D K RL++ GI+
Sbjct: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
Query: 126 VISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKR-ELGASLYLGWAASGLLLLGGGLL-CC 183
SGV L+PV W AH +++F++ V + R E G +L+LGW A LLLGG LL C
Sbjct: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186
Query: 184 TCPSGGSQGPSHY 196
C S HY
Sbjct: 187 ACSSHAPLASGHY 199
>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
Length = 261
Score = 123 bits (309), Expect = 1e-28
Identities = 70/226 (30%), Positives = 119/226 (52%), Gaps = 13/226 (5%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
M++ Q++ +L++LG + + + MW N V + +EGLW SCV QS+G
Sbjct: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNP-VTSVFQYEGLWRSCVRQSSG 59
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDS-KARLVL 119
+C+ Y ++L LP LQA RAL ++ +++ GLLV + KC +DS KA + L
Sbjct: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
Query: 120 TSGIVFVISGVLTLIPVCWTAHAIIRDFY----------NPLVAEAQKR-ELGASLYLGW 168
TSGI+F++SG+ + V A+ ++ +F+ +V Q R GA+L++GW
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
Query: 169 AASGLLLLGGGLLCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEY 214
A GL L+GG ++C C + ++ Y S +++ P +
Sbjct: 180 VAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGF 225
>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
Length = 261
Score = 122 bits (307), Expect = 2e-28
Identities = 73/226 (32%), Positives = 120/226 (53%), Gaps = 13/226 (5%)
Query: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MA Q LG V++L+G + + + W T + N+ V A ++GLW SCV +S+G
Sbjct: 1 MAVTACQGLGFVVSLIGIAGIIAATCMDQWS-TQDLYNNPVTAVFNYQGLWRSCVRESSG 59
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDS-KARLVL 119
+C+ Y +LL LP LQA RAL ++ +++ GLLV + KC +DS KA + L
Sbjct: 60 FTECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
Query: 120 TSGIVFVISGVLTLIPVCWTAHAIIRDFY----------NPLVAEAQKR-ELGASLYLGW 168
TSGI+F++SG+ + V A+ ++ +F+ +V Q R GA+L++GW
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
Query: 169 AASGLLLLGGGLLCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEY 214
A GL L+GG ++C C + ++ Y S +++ P +
Sbjct: 180 VAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGF 225
>gi|157820127 claudin-like [Homo sapiens]
Length = 229
Score = 110 bits (275), Expect = 9e-25
Identities = 74/198 (37%), Positives = 103/198 (52%), Gaps = 7/198 (3%)
Query: 4 AGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVW-EGLWMSCVVQSTGQM 62
A +Q+ G++L+LLGWV V+ LP WK N + W G+W CV +
Sbjct: 7 AKVQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMET----WIMGIWEVCVDREEVAT 62
Query: 63 QCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEK-DSKARLVLTS 121
CK ++S L+LPQ+LQ AR L V + + L GLL+ G++C + K RL L
Sbjct: 63 VCKAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLG 122
Query: 122 GIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKR-ELGASLYLGWAASGLLLLGGGL 180
+ + TL+PV W AHA I+DF++ + + R E G +LYLGWAA L LGG L
Sbjct: 123 RTLEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLL 182
Query: 181 LCCTCPSGGSQGPSHYMA 198
L + G P MA
Sbjct: 183 LIFSACLGKEDVPFPLMA 200
>gi|33598916 claudin 10 isoform a [Homo sapiens]
Length = 226
Score = 109 bits (273), Expect = 2e-24
Identities = 54/153 (35%), Positives = 91/153 (59%), Gaps = 2/153 (1%)
Query: 30 WKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVIALL 89
WKVT +S++ A V++GLWM+C + G C+ + ++ + +QA R L + A+
Sbjct: 28 WKVTTR-ASSVITATWVYQGLWMNCAGNALGSFHCRPHFTIFKVAGYIQACRGLMIAAVS 86
Query: 90 VALFGLLVYLAGAKCTTCVEEKDSKARLVLTSGIVFVISGVLTLIPVCWTAHAIIRDFYN 149
+ FG + L G KCT +KA++ +GIVF++SG+ ++ A+ I +F++
Sbjct: 87 LGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFD 146
Query: 150 PLVAEAQKRELGASLYLGWAASGLLLLGGGLLC 182
PL E QK ELGA+L++GWA + L ++GG + C
Sbjct: 147 PLFVE-QKYELGAALFIGWAGASLCIIGGVIFC 178
>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
Length = 207
Score = 93.6 bits (231), Expect = 1e-19
Identities = 52/153 (33%), Positives = 83/153 (54%), Gaps = 21/153 (13%)
Query: 30 WKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVIALL 89
WKVT +S++ A V++GLWM+C +QA R L + A+
Sbjct: 28 WKVTTR-ASSVITATWVYQGLWMNCAGY-------------------IQACRGLMIAAVS 67
Query: 90 VALFGLLVYLAGAKCTTCVEEKDSKARLVLTSGIVFVISGVLTLIPVCWTAHAIIRDFYN 149
+ FG + L G KCT +KA++ +GIVF++SG+ ++ A+ I +F++
Sbjct: 68 LGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFD 127
Query: 150 PLVAEAQKRELGASLYLGWAASGLLLLGGGLLC 182
PL E QK ELGA+L++GWA + L ++GG + C
Sbjct: 128 PLFVE-QKYELGAALFIGWAGASLCIIGGVIFC 159
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,313,880
Number of Sequences: 37866
Number of extensions: 346342
Number of successful extensions: 1268
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1186
Number of HSP's gapped (non-prelim): 57
length of query: 220
length of database: 18,247,518
effective HSP length: 98
effective length of query: 122
effective length of database: 14,536,650
effective search space: 1773471300
effective search space used: 1773471300
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.