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Search of human proteins with 153792227
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens]
(708 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153791507 leucine rich repeat neuronal 3 [Homo sapiens] 1426 0.0
gi|153792651 leucine rich repeat neuronal 3 [Homo sapiens] 1426 0.0
gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens] 1426 0.0
gi|153791330 leucine rich repeat neuronal 1 [Homo sapiens] 782 0.0
gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens] 638 0.0
gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens] 638 0.0
gi|22749183 leucine rich repeat and Ig domain containing 2 [Homo... 171 2e-42
gi|50263044 leucine-rich repeat neuronal 6A [Homo sapiens] 164 3e-40
gi|157426829 leucine rich repeat and Ig domain containing 3 [Hom... 157 2e-38
gi|51317373 netrin-G1 ligand [Homo sapiens] 145 2e-34
gi|52138725 leucine rich repeat and Ig domain containing 4 [Homo... 138 2e-32
gi|198041768 synleurin [Homo sapiens] 137 3e-32
gi|122937309 leucine rich repeat containing 4B [Homo sapiens] 130 4e-30
gi|31542244 leucine rich repeat and fibronectin type III domain ... 129 7e-30
gi|15029530 leucine rich repeat containing 4 [Homo sapiens] 129 7e-30
gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 129 7e-30
gi|7662320 leucine-rich repeats and immunoglobulin-like domains ... 128 2e-29
gi|205277468 leucine rich repeat containing 15 isoform a [Homo s... 127 5e-29
gi|18677767 leucine rich repeat containing 15 isoform b [Homo sa... 126 8e-29
gi|109150416 peroxidasin [Homo sapiens] 115 2e-25
gi|149773484 leucine rich repeat and fibronectin type III domain... 114 3e-25
gi|4758460 glycoprotein V (platelet) [Homo sapiens] 113 5e-25
gi|27363458 leucine rich repeat and fibronectin type III domain ... 112 2e-24
gi|40255157 leucine-rich repeats and immunoglobulin-like domains... 111 2e-24
gi|209862903 leucine-rich repeats and immunoglobulin-like domain... 111 2e-24
gi|34577057 fibronectin leucine rich transmembrane protein 1 [Ho... 110 3e-24
gi|194440719 chondroadherin-like [Homo sapiens] 110 4e-24
gi|86990456 leucine rich repeat transmembrane neuronal 1 [Homo s... 109 8e-24
gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo ... 109 1e-23
gi|7019381 fibronectin leucine rich transmembrane protein 2 [Hom... 109 1e-23
>gi|153791507 leucine rich repeat neuronal 3 [Homo sapiens]
Length = 708
Score = 1426 bits (3692), Expect = 0.0
Identities = 708/708 (100%), Positives = 708/708 (100%)
Query: 1 MKDMPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGL 60
MKDMPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGL
Sbjct: 1 MKDMPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGL 60
Query: 61 LTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLS 120
LTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLS
Sbjct: 61 LTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLS 120
Query: 121 VYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN 180
VYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN
Sbjct: 121 VYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN 180
Query: 181 SKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLES 240
SKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLES
Sbjct: 181 SKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLES 240
Query: 241 ISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISI 300
ISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISI
Sbjct: 241 ISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISI 300
Query: 301 DSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNL 360
DSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNL
Sbjct: 301 DSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNL 360
Query: 361 KEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICL 420
KEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICL
Sbjct: 361 KEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICL 420
Query: 421 PLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGT 480
PLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGT
Sbjct: 421 PLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGT 480
Query: 481 LDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQANSVLVS 540
LDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQANSVLVS
Sbjct: 481 LDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQANSVLVS 540
Query: 541 WKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQ 600
WKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQ
Sbjct: 541 WKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQ 600
Query: 601 KNRKKCVNVTTKGLHPDQKEYEKNNTTTLMACLGGLLGIIGVICLISCLSPEMNCDGGHS 660
KNRKKCVNVTTKGLHPDQKEYEKNNTTTLMACLGGLLGIIGVICLISCLSPEMNCDGGHS
Sbjct: 601 KNRKKCVNVTTKGLHPDQKEYEKNNTTTLMACLGGLLGIIGVICLISCLSPEMNCDGGHS 660
Query: 661 YVRNYLQKPTFALGELYPPLINLWEAGKEKSTSLKVKATVIGLPTNMS 708
YVRNYLQKPTFALGELYPPLINLWEAGKEKSTSLKVKATVIGLPTNMS
Sbjct: 661 YVRNYLQKPTFALGELYPPLINLWEAGKEKSTSLKVKATVIGLPTNMS 708
>gi|153792651 leucine rich repeat neuronal 3 [Homo sapiens]
Length = 708
Score = 1426 bits (3692), Expect = 0.0
Identities = 708/708 (100%), Positives = 708/708 (100%)
Query: 1 MKDMPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGL 60
MKDMPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGL
Sbjct: 1 MKDMPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGL 60
Query: 61 LTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLS 120
LTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLS
Sbjct: 61 LTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLS 120
Query: 121 VYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN 180
VYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN
Sbjct: 121 VYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN 180
Query: 181 SKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLES 240
SKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLES
Sbjct: 181 SKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLES 240
Query: 241 ISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISI 300
ISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISI
Sbjct: 241 ISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISI 300
Query: 301 DSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNL 360
DSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNL
Sbjct: 301 DSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNL 360
Query: 361 KEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICL 420
KEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICL
Sbjct: 361 KEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICL 420
Query: 421 PLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGT 480
PLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGT
Sbjct: 421 PLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGT 480
Query: 481 LDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQANSVLVS 540
LDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQANSVLVS
Sbjct: 481 LDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQANSVLVS 540
Query: 541 WKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQ 600
WKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQ
Sbjct: 541 WKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQ 600
Query: 601 KNRKKCVNVTTKGLHPDQKEYEKNNTTTLMACLGGLLGIIGVICLISCLSPEMNCDGGHS 660
KNRKKCVNVTTKGLHPDQKEYEKNNTTTLMACLGGLLGIIGVICLISCLSPEMNCDGGHS
Sbjct: 601 KNRKKCVNVTTKGLHPDQKEYEKNNTTTLMACLGGLLGIIGVICLISCLSPEMNCDGGHS 660
Query: 661 YVRNYLQKPTFALGELYPPLINLWEAGKEKSTSLKVKATVIGLPTNMS 708
YVRNYLQKPTFALGELYPPLINLWEAGKEKSTSLKVKATVIGLPTNMS
Sbjct: 661 YVRNYLQKPTFALGELYPPLINLWEAGKEKSTSLKVKATVIGLPTNMS 708
>gi|153792227 leucine rich repeat neuronal 3 [Homo sapiens]
Length = 708
Score = 1426 bits (3692), Expect = 0.0
Identities = 708/708 (100%), Positives = 708/708 (100%)
Query: 1 MKDMPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGL 60
MKDMPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGL
Sbjct: 1 MKDMPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGL 60
Query: 61 LTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLS 120
LTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLS
Sbjct: 61 LTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLS 120
Query: 121 VYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN 180
VYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN
Sbjct: 121 VYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN 180
Query: 181 SKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLES 240
SKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLES
Sbjct: 181 SKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLES 240
Query: 241 ISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISI 300
ISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISI
Sbjct: 241 ISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISI 300
Query: 301 DSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNL 360
DSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNL
Sbjct: 301 DSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNL 360
Query: 361 KEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICL 420
KEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICL
Sbjct: 361 KEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICL 420
Query: 421 PLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGT 480
PLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGT
Sbjct: 421 PLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGT 480
Query: 481 LDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQANSVLVS 540
LDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQANSVLVS
Sbjct: 481 LDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQANSVLVS 540
Query: 541 WKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQ 600
WKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQ
Sbjct: 541 WKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQ 600
Query: 601 KNRKKCVNVTTKGLHPDQKEYEKNNTTTLMACLGGLLGIIGVICLISCLSPEMNCDGGHS 660
KNRKKCVNVTTKGLHPDQKEYEKNNTTTLMACLGGLLGIIGVICLISCLSPEMNCDGGHS
Sbjct: 601 KNRKKCVNVTTKGLHPDQKEYEKNNTTTLMACLGGLLGIIGVICLISCLSPEMNCDGGHS 660
Query: 661 YVRNYLQKPTFALGELYPPLINLWEAGKEKSTSLKVKATVIGLPTNMS 708
YVRNYLQKPTFALGELYPPLINLWEAGKEKSTSLKVKATVIGLPTNMS
Sbjct: 661 YVRNYLQKPTFALGELYPPLINLWEAGKEKSTSLKVKATVIGLPTNMS 708
>gi|153791330 leucine rich repeat neuronal 1 [Homo sapiens]
Length = 716
Score = 782 bits (2020), Expect = 0.0
Identities = 379/683 (55%), Positives = 508/683 (74%), Gaps = 3/683 (0%)
Query: 10 VLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPA 69
++LGL +T+L ++ + +CP+LC CEIRPWFTP+S Y EA+TVDCNDL L P+ L +
Sbjct: 13 LVLGLLMTSLTESSIQNSECPQLCVCEIRPWFTPQSTYREATTVDCNDLRLTRIPSNLSS 72
Query: 70 NTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLT 129
+TQ+LLLQ+NNIAK NLT LD SQNN +++ + + + QL +++LEEN++T
Sbjct: 73 DTQVLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQIT 132
Query: 130 ELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPN 189
E+ + CL +LSNLQELYINHN +STIS AF GL NLLRLHLNSN+L++I+S+WFD+ PN
Sbjct: 133 EMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPN 192
Query: 190 LEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLI 249
LEILMIGENP+I I DMNFKPL NLRSLV+AG+ LT+IP NALVGL++LES+SFYDN+L+
Sbjct: 193 LEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLV 252
Query: 250 KVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLP 309
KVP +ALQKV NLKFLDLNKNPI++I+ GDF NML LKELGINNM EL+S+D A+DNLP
Sbjct: 253 KVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLP 312
Query: 310 DLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNP 369
+L K+EATNNP+LSYIH AF +P LESLMLN+NAL+A+Y T+ESLPNL+EISIHSNP
Sbjct: 313 ELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNP 372
Query: 370 IRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLIAPESFP 429
+RCDCVI W+N NKTNIRFMEP S+FC PPE++G V++V +D E CLP+I+ +SFP
Sbjct: 373 LRCDCVIHWINSNKTNIRFMEPLSMFCAMPPEYKGHQVKEVLIQDSSEQCLPMISHDSFP 432
Query: 430 SNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVTPK 489
+ LNV+ G+ V CRA AEP+PEIYW+TP G K+ TL+DK+ + SEGTL+I+ + +
Sbjct: 433 NRLNVDIGTTVFLDCRAMAEPEPEIYWVTPIGNKITVETLSDKYKLSSEGTLEISNIQIE 492
Query: 490 EGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQANSVLVSWKASSKILK 549
+ G YTC+A N+ GAD + IKV+G+ D L I ++ +++S+LVSWK +S ++
Sbjct: 493 DSGRYTCVAQNVQGADTRVATIKVNGTL-LDGTQVLKIYVKQTESHSILVSWKVNSNVMT 551
Query: 550 SSVKW-TAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQKNRKKCVN 608
S++KW +A +K +N H +AR+P DV YNLTHL PST+Y++C+ + I+Q+ +K CVN
Sbjct: 552 SNLKWSSATMKIDNPHITYTARVPVDVHEYNLTHLQPSTDYEVCLTVSNIHQQTQKSCVN 611
Query: 609 VTTKGLHPDQKEYEKNNTTTLMACLGGLLGIIGVICLISCLSPEMNCDGGHSYVRNYLQK 668
VTTK ++ +T L A +G + +I + + + H ++ Y+QK
Sbjct: 612 VTTKNAAFAVDISDQETSTALAAVMGSMFAVISLASIAVYFAKRFKRKNYHHSLKKYMQK 671
Query: 669 -PTFALGELYPPLINLWEAGKEK 690
+ L ELYPPLINLWE EK
Sbjct: 672 TSSIPLNELYPPLINLWEGDSEK 694
>gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens]
Length = 713
Score = 638 bits (1645), Expect = 0.0
Identities = 322/633 (50%), Positives = 426/633 (67%), Gaps = 16/633 (2%)
Query: 17 TTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLL 76
T V V V CP C C+IRPW+TPRS Y EA+TVDCNDL L P LPA TQ LLL
Sbjct: 17 TAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPALPAGTQTLLL 76
Query: 77 QTNNIAKIEYST-DFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKC 135
Q+N+I +++ S + NLT LDLSQN+ S + + +PQLLS++LEEN+LT L +
Sbjct: 77 QSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHS 136
Query: 136 LSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMI 195
+ L++LQELY+NHN L I+P AF GL NLLRLHLNSN L+ I+S+WF+ LPNLEILMI
Sbjct: 137 FAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMI 196
Query: 196 GENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVA 255
G N + I DMNF+PL NLRSLV+AG+NL EI D AL GL++LES+SFYDN+L +VP A
Sbjct: 197 GGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRA 256
Query: 256 LQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIE 315
L++V LKFLDLNKNP+ R+ GDF+NMLHLKELG+NNM EL+SID A+ NLP+L K++
Sbjct: 257 LEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLD 316
Query: 316 ATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCV 375
TNNPRLS+IHP AF LP++E+LMLN+NALSAL+ T+ESLPNL+E+ +H NPIRCDCV
Sbjct: 317 ITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGNPIRCDCV 376
Query: 376 IRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLIAPESFPSNLNVE 435
IRW N T +RF+EP S C +PP+ Q VR+V FR+M + CLPLI+P SFP +L V
Sbjct: 377 IRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHCLPLISPRSFPPSLQVA 436
Query: 436 AGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVTPKEGGLYT 495
+G + HCRA AEP+PEIYW+TP+G +L P ++ V+ EGTL++ VT +E GLYT
Sbjct: 437 SGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEGTLELRRVTAEEAGLYT 496
Query: 496 CIATNLVGADLKSVMIKVDGSFPQ---DNNGSLNIKIRDIQANSVLVSWKASSKILKSSV 552
C+A NLVGAD K+V + V + Q D L +++++ +L+SW + +++
Sbjct: 497 CVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYHILLSWVTPPNTVSTNL 556
Query: 553 KWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQKNRKKCVNVTTK 612
W++ A AR+P YN+T L +TEY C+ + + CV TK
Sbjct: 557 TWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVAFADAHTQLACVWARTK 616
Query: 613 GLHPDQKEYEKNNTTTLMACLGGLLGIIGVICL 645
T+ LG G+I ++ L
Sbjct: 617 ------------EATSCHRALGDRPGLIAILAL 637
>gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens]
Length = 713
Score = 638 bits (1645), Expect = 0.0
Identities = 322/633 (50%), Positives = 426/633 (67%), Gaps = 16/633 (2%)
Query: 17 TTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLL 76
T V V V CP C C+IRPW+TPRS Y EA+TVDCNDL L P LPA TQ LLL
Sbjct: 17 TAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPALPAGTQTLLL 76
Query: 77 QTNNIAKIEYST-DFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKC 135
Q+N+I +++ S + NLT LDLSQN+ S + + +PQLLS++LEEN+LT L +
Sbjct: 77 QSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHS 136
Query: 136 LSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMI 195
+ L++LQELY+NHN L I+P AF GL NLLRLHLNSN L+ I+S+WF+ LPNLEILMI
Sbjct: 137 FAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMI 196
Query: 196 GENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVA 255
G N + I DMNF+PL NLRSLV+AG+NL EI D AL GL++LES+SFYDN+L +VP A
Sbjct: 197 GGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRA 256
Query: 256 LQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIE 315
L++V LKFLDLNKNP+ R+ GDF+NMLHLKELG+NNM EL+SID A+ NLP+L K++
Sbjct: 257 LEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLD 316
Query: 316 ATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCV 375
TNNPRLS+IHP AF LP++E+LMLN+NALSAL+ T+ESLPNL+E+ +H NPIRCDCV
Sbjct: 317 ITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGNPIRCDCV 376
Query: 376 IRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLIAPESFPSNLNVE 435
IRW N T +RF+EP S C +PP+ Q VR+V FR+M + CLPLI+P SFP +L V
Sbjct: 377 IRWANATGTRVRFIEPQSTLCAEPPDLQRLPVREVPFREMTDHCLPLISPRSFPPSLQVA 436
Query: 436 AGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVTPKEGGLYT 495
+G + HCRA AEP+PEIYW+TP+G +L P ++ V+ EGTL++ VT +E GLYT
Sbjct: 437 SGESMVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYPEGTLELRRVTAEEAGLYT 496
Query: 496 CIATNLVGADLKSVMIKVDGSFPQ---DNNGSLNIKIRDIQANSVLVSWKASSKILKSSV 552
C+A NLVGAD K+V + V + Q D L +++++ +L+SW + +++
Sbjct: 497 CVAQNLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYHILLSWVTPPNTVSTNL 556
Query: 553 KWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQKNRKKCVNVTTK 612
W++ A AR+P YN+T L +TEY C+ + + CV TK
Sbjct: 557 TWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVAFADAHTQLACVWARTK 616
Query: 613 GLHPDQKEYEKNNTTTLMACLGGLLGIIGVICL 645
T+ LG G+I ++ L
Sbjct: 617 ------------EATSCHRALGDRPGLIAILAL 637
>gi|22749183 leucine rich repeat and Ig domain containing 2 [Homo
sapiens]
Length = 606
Score = 171 bits (434), Expect = 2e-42
Identities = 133/529 (25%), Positives = 224/529 (42%), Gaps = 64/529 (12%)
Query: 12 LGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANT 71
LGLA+ + + CP C C + +V C+ L+ P +P T
Sbjct: 13 LGLAVVLIFMG--STIGCPARCECSA-----------QNKSVSCHRRRLIAIPEGIPIET 59
Query: 72 QILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTEL 131
+IL DLS+N L SV P L + L +N + +
Sbjct: 60 KIL-----------------------DLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANV 96
Query: 132 PEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLE 191
+ L NL+ L + N L + G F GL NL +L ++ N++ ++ F L NL+
Sbjct: 97 EPGAFNNLFNLRSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLK 156
Query: 192 ILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKV 251
L +G+N ++ I F L++L L + NLT +P AL L +L S+ + +
Sbjct: 157 SLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNM 216
Query: 252 PHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDL 311
P A +++ +LK L+++ P+ + + L+L L + N L ++ LA +L L
Sbjct: 217 PVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSLSVTN-TNLSTVPFLAFKHLVYL 275
Query: 312 RKIEATNNP-----------------------RLSYIHPNAFFRLPKLESLMLNSNALSA 348
+ + NP +L I P++F L L L ++ N L
Sbjct: 276 THLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLET 335
Query: 349 LYHGTIESLPNLKEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVR 408
L S L+ +SI++NP+ CDC + W+ + ++F + C P + ++ +
Sbjct: 336 LEENVFSSPRALEVLSINNNPLACDCRLLWILQRQPTLQFGGQQPM-CAGPDTIRERSFK 394
Query: 409 QVHFR--DMMEICLPLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLP 466
H C E +L V+ G V C A +PQP I W+TP ++ +
Sbjct: 395 DFHSTALSFYFTCKKPKIREKKLQHLLVDEGQTVQLECSADGDPQPVISWVTPR-RRFIT 453
Query: 467 NTLTDKFYVHSEGTLDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDG 515
+ V +GTL+I ++ G+Y CIA+N G D + + V G
Sbjct: 454 TKSNGRATVLGDGTLEIRFAQDQDSGMYVCIASNAAGNDTFTASLTVKG 502
>gi|50263044 leucine-rich repeat neuronal 6A [Homo sapiens]
Length = 620
Score = 164 bits (414), Expect = 3e-40
Identities = 126/436 (28%), Positives = 191/436 (43%), Gaps = 60/436 (13%)
Query: 123 LEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSK 182
L +N++ L + + +L+EL +N N++S + PGAF L NL L L SNRL++I
Sbjct: 78 LGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLG 137
Query: 183 WFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESIS 242
F L NL L I EN I+ + D F+ L NL+SL + +L I A GL +LE ++
Sbjct: 138 VFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLT 197
Query: 243 FYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMP------- 295
L +P AL + L L L IN IR F + LK L I++ P
Sbjct: 198 LEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTP 257
Query: 296 ----------------ELISIDSLAVDNLPDLRKIEATNNP------------------- 320
L ++ LAV +L LR + + NP
Sbjct: 258 NCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQ 317
Query: 321 ----RLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVI 376
+L+ + P AF L L L ++ N L+ L S+ NL+ + + SNP+ CDC +
Sbjct: 318 LVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLACDCRL 377
Query: 377 RWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLP-------LIAPESFP 429
W+ + + F C P QG+ F+D ++ LP +
Sbjct: 378 LWVFRRRWRLNFNRQQPT-CATPEFVQGK-----EFKDFPDVLLPNYFTCRRARIRDRKA 431
Query: 430 SNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVTPK 489
+ V+ G V F CRA +P P I W++P + L+ + V +GTL++ +
Sbjct: 432 QQVFVDEGHTVQFVCRADGDPPPAILWLSPR-KHLVSAKSNGRLTVFPDGTLEVRYAQVQ 490
Query: 490 EGGLYTCIATNLVGAD 505
+ G Y CIA N G D
Sbjct: 491 DNGTYLCIAANAGGND 506
Score = 60.8 bits (146), Expect = 4e-09
Identities = 34/111 (30%), Positives = 62/111 (55%)
Query: 90 FPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINH 149
+ +NLT L ++ NL++V + V+ + L + L N ++ + L EL LQE+ +
Sbjct: 261 YGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVG 320
Query: 150 NLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPI 200
L+ + P AF GL+ L L+++ N+L + F ++ NLE L++ NP+
Sbjct: 321 GQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 371
Score = 37.0 bits (84), Expect = 0.063
Identities = 18/66 (27%), Positives = 34/66 (51%)
Query: 306 DNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISI 365
+ +P ++ R+ ++ + F P LE L LN N +SA+ G +L NL+ + +
Sbjct: 67 EGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGL 126
Query: 366 HSNPIR 371
SN ++
Sbjct: 127 RSNRLK 132
>gi|157426829 leucine rich repeat and Ig domain containing 3 [Homo
sapiens]
Length = 592
Score = 157 bits (398), Expect = 2e-38
Identities = 134/546 (24%), Positives = 213/546 (39%), Gaps = 114/546 (20%)
Query: 11 LLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPAN 70
+L L + L A CP C C + + V C L P +PA
Sbjct: 7 VLSLPLLLLPAAPPPAGGCPARCECTV-----------QTRAVACTRRRLTAVPDGIPAE 55
Query: 71 TQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTE 130
T++L +LS+N + + ++ +P L + L EN +
Sbjct: 56 TRLL-----------------------ELSRNRIRCLNPGDLAALPALEELDLSENAIAH 92
Query: 131 LPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNL 190
+ + L L+ L + N L I PG F L NL L L+ N+L ++ F L +L
Sbjct: 93 VEPGAFANLPRLRVLRLRGNQLKLIPPGVFTRLDNLTLLDLSENKLVILLDYTFQDLHSL 152
Query: 191 EILMIGENPIIRIKDMNFKPLINLRSLVIAGINLT------------------------- 225
L +G+N ++ + F L+ L L + NLT
Sbjct: 153 RRLEVGDNDLVFVSRRAFAGLLALEELTLERCNLTALSGESLGHLRSLGALRLRHLAIAS 212
Query: 226 ------------------------EIPDNALVGLENLESISFYDNRLIKVPHVALQKVVN 261
E+ +L GL NL S+S + VP AL+ +
Sbjct: 213 LEDQNFRRLPGLLHLEIDNWPLLEEVAAGSLRGL-NLTSLSVTHTNITAVPAAALRHQAH 271
Query: 262 LKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPR 321
L L+L+ NPI+ + RG F +++ L+EL +
Sbjct: 272 LTCLNLSHNPISTVPRGSFRDLVRLRELHL--------------------------AGAL 305
Query: 322 LSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWMNM 381
L+ + P AF L ++ L L++N LS L T S+ L+ + + NP+ CDC + W+
Sbjct: 306 LAVVEPQAFLGLRQIRLLNLSNNLLSTLEESTFHSVNTLETLRVDGNPLACDCRLLWIVQ 365
Query: 382 NKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMME--ICLPLIAPESFPSNLNVEAGSY 439
+ + F + C P E +G +R + + E +C E + AG
Sbjct: 366 RRKTLNF-DGRLPACATPAEVRGDALRNLPDSVLFEYFVCRKPKIRERRLQRVTATAGED 424
Query: 440 VSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVTPKEGGLYTCIAT 499
V F CRA EP P + W+TP + + T + V GTL+I P++ G YTC+A+
Sbjct: 425 VRFLCRAEGEPAPTVAWVTPQ-HRPVTATSAGRARVLPGGTLEIQDARPQDSGTYTCVAS 483
Query: 500 NLVGAD 505
N G D
Sbjct: 484 NAGGND 489
>gi|51317373 netrin-G1 ligand [Homo sapiens]
Length = 640
Score = 145 bits (365), Expect = 2e-34
Identities = 136/509 (26%), Positives = 214/509 (42%), Gaps = 99/509 (19%)
Query: 10 VLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPA 69
VLL L + + V + CP +C+C + S V C L P +
Sbjct: 29 VLLALQLLVVAGLVRAQT-CPSVCSCS-----------NQFSKVICVRKNLREVPDGIST 76
Query: 70 NTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLT 129
NT++L L N I I+ ++ K + L + L N +
Sbjct: 77 NTRLLNLHENQIQIIKVNS-----------------------FKHLRHLEILQLSRNHIR 113
Query: 130 ELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPN 189
+ + L+NL L + N L+TI GAF+ L L L L +N ++ I S F+ +P+
Sbjct: 114 TIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPS 173
Query: 190 LEILMIGE-NPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRL 248
L L +GE + I + F+ L NLR L +A NL EIP+
Sbjct: 174 LRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPN------------------- 214
Query: 249 IKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNL 308
L ++ L LDL+ N ++ IR G F ++HL++L + I S
Sbjct: 215 -------LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWM--------IQS------ 253
Query: 309 PDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSN 368
++ I NAF L L + L N L+ L H L +L+ I +H N
Sbjct: 254 ------------QIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 301
Query: 369 PIRCDCVIRWMNMNKTNIRFMEPDSLFCV----DPPEFQGQNVRQVHFRDMMEICLPLIA 424
P C+C I W++ I+ M P + C PP +G+ + ++ ++ P+I
Sbjct: 302 PWNCNCDILWLSW---WIKDMAPSNTACCARCNTPPNLKGRYIGELD-QNYFTCYAPVIV 357
Query: 425 PESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDIN 484
P++LNV G CRA+ + WITP+G + + V S+GTL+
Sbjct: 358 EP--PADLNVTEGMAAELKCRASTS-LTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFT 414
Query: 485 GVTPKEGGLYTCIATNLVGADLKSVMIKV 513
VT ++ G+YTC+ +N VG S + V
Sbjct: 415 NVTVQDTGMYTCMVSNSVGNTTASATLNV 443
>gi|52138725 leucine rich repeat and Ig domain containing 4 [Homo
sapiens]
Length = 593
Score = 138 bits (348), Expect = 2e-32
Identities = 132/527 (25%), Positives = 219/527 (41%), Gaps = 74/527 (14%)
Query: 29 CPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYST 88
CP +C C +P V C L P LP +T++L
Sbjct: 31 CPAVCDCTSQP-----------QAVLCGHRQLEAVPGGLPLDTELL-------------- 65
Query: 89 DFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYIN 148
DLS N L + + ++ L + L N+L+ L L +L L +
Sbjct: 66 ---------DLSGNRLWGLQQGMLSRLSLLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQ 116
Query: 149 HNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNF 208
N L + PG F GL L L L N++ + F L +L+ L +G+N ++ + F
Sbjct: 117 GNRLRIMGPGVFSGLSALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAF 176
Query: 209 KPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLN 268
L L +L + NL+ +P AL L L ++ + + ++P AL+ + LK L+++
Sbjct: 177 AGLAKLSTLTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGLGQLKELEIH 236
Query: 269 KNP-INRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNP------- 320
P + + G L+L L I L S+ A+ +L LR ++ + NP
Sbjct: 237 LWPSLEALDPGSLVG-LNLSSLAITRC-NLSSVPFQALYHLSFLRVLDLSQNPISAIPAR 294
Query: 321 ----------------RLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEIS 364
L+ I +AF L L + NAL L S L +
Sbjct: 295 RLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLR 354
Query: 365 IHSNPIRCDCVIRWMNMNKTNIRF-MEPDSLFCVDPPEFQGQNVRQVHFRDMME----IC 419
+ NP+ CDC + W+ + ++ F M P + C P QG+++++ F D++ C
Sbjct: 355 LSGNPLTCDCRLLWLLRLRRHLDFGMSPPA--CAGPHHVQGKSLKE--FSDILPPGHFTC 410
Query: 420 LPLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEG 479
P + +S P + E G + F C +P P + W+ P G L + V +G
Sbjct: 411 KPALIRKSGPRWVIAEEGGHAVFSCSGDGDPAPTVSWMRPHGAWL---GRAGRVRVLEDG 467
Query: 480 TLDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLN 526
TL+I V ++ G Y C+ +N+ G D ++V P NG+L+
Sbjct: 468 TLEIRSVQLRDRGAYVCVVSNVAGNDSLRTWLEVIQVEPP--NGTLS 512
>gi|198041768 synleurin [Homo sapiens]
Length = 622
Score = 137 bits (346), Expect = 3e-32
Identities = 103/365 (28%), Positives = 183/365 (50%), Gaps = 14/365 (3%)
Query: 53 VDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYSTDFPV-NLTGLDLSQNNLSSVTNIN 111
++C +LGL + P P +T L L NNI+ I S + +L L L +N+ V
Sbjct: 44 INCRNLGLSSIPKNFPESTVFLYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKA 103
Query: 112 VKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHL 171
++ L ++L N + L L NL+ LY+ +N +S + G F L ++ L+L
Sbjct: 104 FVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNL 163
Query: 172 NSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNA 231
NRL ++ S F + L IL + N I+RI + F+ L NL L + NLT++P NA
Sbjct: 164 QRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNA 223
Query: 232 LVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGI 291
L++L +S N + + A + + NL++L L + I + R FS + +LK L I
Sbjct: 224 FEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHL-I 282
Query: 292 NNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRL-PKLESLMLNSNALSALY 350
+ +L +++S L +L ++ N R+ I + F + L+ L L+ N L+AL+
Sbjct: 283 LSHNDLENLNSDTFSLLKNLIYLKLDRN-RIISIDNDTFENMGASLKILNLSFNNLTALH 341
Query: 351 HGTIESLPNLKEISIHSNPIRCDCVI----RWMNMNKTNIRFMEPDSLFCVDPPEFQGQN 406
++ L +L + +SNP C+C + W+ + + +++C +PP +G+
Sbjct: 342 PRVLKPLSSLIHLQANSNPWECNCKLLGLRDWLASSAITL------NIYCQNPPSMRGRA 395
Query: 407 VRQVH 411
+R ++
Sbjct: 396 LRYIN 400
>gi|122937309 leucine rich repeat containing 4B [Homo sapiens]
Length = 713
Score = 130 bits (327), Expect = 4e-30
Identities = 107/404 (26%), Positives = 177/404 (43%), Gaps = 34/404 (8%)
Query: 123 LEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSK 182
L+EN + + L +L+ L ++ NL+ I GAF GL +L L L NRL + ++
Sbjct: 93 LQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQ 152
Query: 183 WFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTE-IPDNALVGLENLESI 241
F+ L L L + NPI I F + +LR L + + E I + A GL NL +
Sbjct: 153 AFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYL 212
Query: 242 SFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISID 301
+ L +P+ L +V L+ L+L+ N ++ IR G F + L++L +
Sbjct: 213 NLGMCNLKDIPN--LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWL---------- 260
Query: 302 SLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLK 361
+ +++ I NAF L LE L L+ N L +L H L L+
Sbjct: 261 ----------------MHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLE 304
Query: 362 EISIHSNPIRCDCVIRWMN-MNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICL 420
+ ++ NP C+C + W++ K + C P +G+ + ++
Sbjct: 305 RVHLNHNPWHCNCDVLWLSWWLKETVPSNTTCCARCHAPAGLKGRYIGELDQSHFTCYAP 364
Query: 421 PLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGT 480
++ P P++LNV G CR T + W+TP+G + + + V +GT
Sbjct: 365 VIVEP---PTDLNVTEGMAAELKCR-TGTSMTSVNWLTPNGTLMTHGSYRVRISVLHDGT 420
Query: 481 LDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGS 524
L+ VT ++ G YTC+ TN G S + V P G+
Sbjct: 421 LNFTNVTVQDTGQYTCMVTNSAGNTTASATLNVSAVDPVAAGGT 464
>gi|31542244 leucine rich repeat and fibronectin type III domain
containing 5 [Homo sapiens]
Length = 719
Score = 129 bits (325), Expect = 7e-30
Identities = 112/429 (26%), Positives = 185/429 (43%), Gaps = 75/429 (17%)
Query: 123 LEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSK 182
L +N +T + K + +++L +L ++ N +S I+P AF L NL LHLNSNRL I +
Sbjct: 58 LADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITND 117
Query: 183 WFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESIS 242
F L NL L++ N LT I A + LE +
Sbjct: 118 MFSGLSNLHHLILNNN------------------------QLTLISSTAFDDVFALEELD 153
Query: 243 FYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDS 302
N L +P A++K+V+L L L+ N I+ I +G FS
Sbjct: 154 LSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFS--------------------- 192
Query: 303 LAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKE 362
+L + +++ T+N +L + P+ F+ + ++ S +S P+
Sbjct: 193 ----HLHKMTRLDVTSN-KLQKLPPDPLFQRAQ---VLATSGIIS----------PSTFA 234
Query: 363 ISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPL 422
+S NP+ C+C + W+ E D C PP G+ + + +C P
Sbjct: 235 LSFGGNPLHCNCELLWLRRLS-----REDDLETCASPPLLTGRYFWSIPEEEF--LCEPP 287
Query: 423 IAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLD 482
+ + V G + C+A +P+P I+WI+P G KL+ N + V+ GTLD
Sbjct: 288 LITR-HTHEMRVLEGQRATLRCKARGDPEPAIHWISPEG-KLISN--ATRSLVYDNGTLD 343
Query: 483 INGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQANSVLVSWK 542
I T K+ G +TCIA+N G + V + + P N + +I D ++ + S K
Sbjct: 344 ILITTVKDTGAFTCIASNPAGEATQIVDLHII-KLPHLLNSTNHIHEPDPGSSDISTSTK 402
Query: 543 ASSKILKSS 551
+ S S+
Sbjct: 403 SGSNTSSSN 411
Score = 75.1 bits (183), Expect = 2e-13
Identities = 63/224 (28%), Positives = 100/224 (44%), Gaps = 20/224 (8%)
Query: 11 LLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPAN 70
L+G+A+ + CP+ C C+I +P + C GLL P +
Sbjct: 10 LIGIAVKAQI--------CPKRCVCQI---LSPNLATL------CAKKGLLFVPPNIDRR 52
Query: 71 TQILLLQTNNIAKIEYSTDFP--VNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKL 128
T L L N + I+ DF +L L LS+N +S +T + L +++L N+L
Sbjct: 53 TVELRLADNFVTNIKRK-DFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRL 111
Query: 129 TELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALP 188
T++ S LSNL L +N+N L+ IS AF + L L L+ N L+ I + +
Sbjct: 112 TKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMV 171
Query: 189 NLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNAL 232
+L L + N I I F L + L + L ++P + L
Sbjct: 172 SLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPL 215
>gi|15029530 leucine rich repeat containing 4 [Homo sapiens]
Length = 653
Score = 129 bits (325), Expect = 7e-30
Identities = 117/442 (26%), Positives = 191/442 (43%), Gaps = 40/442 (9%)
Query: 165 NLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINL 224
N L+L N +QMI + F L +LE+L +G N I +I+ F L +L +L + L
Sbjct: 76 NTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWL 135
Query: 225 TEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNK-NPINRIRRGDFSNM 283
T IP A L L + +N + +P A +V +L LDL + + I G F +
Sbjct: 136 TVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGL 195
Query: 284 LHLKELGIN--------NMPELISIDSLAV--DNLPDLR----------KIEATNNPRLS 323
+LK L + N+ L+ ++ L + ++ P++R K N ++S
Sbjct: 196 FNLKYLNLGMCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVS 255
Query: 324 YIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWMNMNK 383
I NAF L L L L N LS+L H L L E+ +H NP CDC I W+
Sbjct: 256 LIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNPWNCDCDILWL---A 312
Query: 384 TNIRFMEPDSLFCVD----PPEFQGQNVRQVHFRDMMEICLPLIAPESFPSNLNVEAGSY 439
+R P + C P +G+ + +V + + P I P +LN+ G
Sbjct: 313 WWLREYIPTNSTCCGRCHAPMHMRGRYLVEVD-QASFQCSAPFIM--DAPRDLNISEGRM 369
Query: 440 VSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVTPKEGGLYTCIAT 499
CR P + W+ P+G L + + V ++GTL+ + V + G+YTC+ T
Sbjct: 370 AELKCR--TPPMSSVKWLLPNGTVLSHASRHPRISVLNDGTLNFSHVLLSDTGVYTCMVT 427
Query: 500 NLVGADLKSVMIKVDGSFPQDNNGS----LNIKIRDIQANSVLVSWKASSKILKSSVKWT 555
N+ G S + V + +N S + ++ +I +K + +S +
Sbjct: 428 NVAGNSNASAYLNVSTAELNTSNYSFFTTVTVETTEISPEDTTRKYK---PVPTTSTGYQ 484
Query: 556 AFVKTENSHAAQSARIPSDVKV 577
T + Q+ R+P V V
Sbjct: 485 PAYTTSTTVLIQTTRVPKQVAV 506
Score = 97.4 bits (241), Expect = 4e-20
Identities = 76/271 (28%), Positives = 136/271 (50%), Gaps = 17/271 (6%)
Query: 28 DCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYS 87
+CP +C+C + S V C GL P +P+NT+ L L NNI I+
Sbjct: 45 NCPSVCSCS-----------NQFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQAD 93
Query: 88 TDFPV-NLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELY 146
T + +L L L +N++ + + L ++ L +N LT +P LS L+EL+
Sbjct: 94 TFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELW 153
Query: 147 INHNLLSTISPGAFIGLHNLLRLHLNS-NRLQMINSKWFDALPNLEILMIGENPIIRIKD 205
+ +N + +I AF + +L+RL L +L+ I+ F+ L NL+ L +G + IKD
Sbjct: 154 LRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLG---MCNIKD 210
Query: 206 M-NFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKF 264
M N PL+ L L ++G + EI + GL +L+ + ++++ + A + +L
Sbjct: 211 MPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVE 270
Query: 265 LDLNKNPINRIRRGDFSNMLHLKELGINNMP 295
L+L N ++ + F+ + +L EL +++ P
Sbjct: 271 LNLAHNNLSSLPHDLFTPLRYLVELHLHHNP 301
>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
[Homo sapiens]
Length = 1093
Score = 129 bits (325), Expect = 7e-30
Identities = 134/581 (23%), Positives = 226/581 (38%), Gaps = 105/581 (18%)
Query: 11 LLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPAN 70
LL L + + A + C CTC ++DC GL P LP+
Sbjct: 23 LLLLRLEPVTAAAGPRAPCAAACTCA-------------GDSLDCGGRGLAALPGDLPSW 69
Query: 71 TQILLLQTNNIAKIEYS--TDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKL 128
T+ L L N +++I+ + D P NL + L+ N L++V ++ ++S++L+ NK+
Sbjct: 70 TRSLNLSYNKLSEIDPAGFEDLP-NLQEVYLNNNELTAVPSLGAASS-HVVSLFLQHNKI 127
Query: 129 ------------------------TELPEKCLSELSNLQELYINHNLLSTISPGAFIGLH 164
TE+ C ++EL + N + T+ GAF GL
Sbjct: 128 RSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLS 187
Query: 165 ------------------------NLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPI 200
L +L LN NR+++I F L +LE+L + N I
Sbjct: 188 RSLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNI 247
Query: 201 IRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGL------------------------E 236
++ D F L + L + +L E+ +L GL +
Sbjct: 248 SKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQ 307
Query: 237 NLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGI--NNM 294
L + N L ++ +L ++ +L L L+ N I+ I G F + L+ L + N +
Sbjct: 308 KLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEI 367
Query: 295 PELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTI 354
I S A L L K+ N ++ + AF L LE L L NA+ ++
Sbjct: 368 SGTIEDTSGAFSGLDSLSKLTLFGN-KIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAF 426
Query: 355 ESLPNLKEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRD 414
+ NLKE+ I S+ CDC ++W+ + C P +GQ++ V
Sbjct: 427 VKMKNLKELHISSDSFLCDCQLKWLPPWLIGRMLQAFVTATCAHPESLKGQSIFSVPPES 486
Query: 415 MMEICLPLIAPE--SFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDK 472
+C + P+ + P G + F C A + + + ++L N +
Sbjct: 487 F--VCDDFLKPQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMEN 544
Query: 473 F-YVHSEG--------TLDINGVTPKEGGLYTCIATNLVGA 504
F +VH++ L + VT G Y C+ TN G+
Sbjct: 545 FVHVHAQDGEVMEYTTILHLRQVTFGHEGRYQCVITNHFGS 585
Score = 40.4 bits (93), Expect = 0.006
Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 5/73 (6%)
Query: 434 VEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEG-TLDINGVTPKEGG 492
V G V+ C+AT P P I W G + P +LT++ ++ + L + V ++ G
Sbjct: 704 VSVGETVALQCKATGNPPPRITWF--KGDR--PLSLTERHHLTPDNQLLVVQNVVAEDAG 759
Query: 493 LYTCIATNLVGAD 505
YTC +N +G +
Sbjct: 760 RYTCEMSNTLGTE 772
Score = 33.9 bits (76), Expect = 0.53
Identities = 17/76 (22%), Positives = 28/76 (36%)
Query: 429 PSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVTP 488
P ++ + + C AT P P+I W G + + I V
Sbjct: 605 PHDITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKI 664
Query: 489 KEGGLYTCIATNLVGA 504
+ G+Y+C A N G+
Sbjct: 665 DDAGVYSCTAQNSAGS 680
>gi|7662320 leucine-rich repeats and immunoglobulin-like domains 2
[Homo sapiens]
Length = 1065
Score = 128 bits (322), Expect = 2e-29
Identities = 117/478 (24%), Positives = 206/478 (43%), Gaps = 43/478 (8%)
Query: 41 FTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYST--DFPVNLTGLD 98
F P ++ S+ +++ +FP + L L N I +E + +L +
Sbjct: 142 FYPALESLDLSSNIISEIKTSSFPRM---QLKYLNLSNNRITTLEAGCFDNLSSSLLVVK 198
Query: 99 LSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPG 158
L++N +S + + K+P L + L+ N++ + L +L+ L + N +S + G
Sbjct: 199 LNRNRMSMIPP-KIFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDG 257
Query: 159 AFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLV 218
AF GL+N+ L L N L +N W L L+ L + +N I RI ++ L L
Sbjct: 258 AFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELD 317
Query: 219 IAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRG 278
++ LT + ++A VGL LE ++ DNR+ + + + NL+ LDL N I+
Sbjct: 318 LSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEIS----- 372
Query: 279 DFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLES 338
I S A L L K+ N ++ I AF L LE
Sbjct: 373 -----------------WAIEDASEAFAGLTSLTKLILQGN-QIKSITKKAFIGLESLEH 414
Query: 339 LMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVD 398
L LN+NA+ ++ S +LKE+ ++++ + CDC ++W+ + F ++ C
Sbjct: 415 LDLNNNAIMSIQENAF-SQTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAH 473
Query: 399 PPEFQGQNVRQVHFRDMMEICLPLIAPE--SFPSNLNVEAGSYVSFHCRATAEPQPEIYW 456
P GQ++ V +D +C + P+ + P + G V+ C A + +
Sbjct: 474 PEWLAGQSILNVDLKDF--VCDDFLKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMST 531
Query: 457 ITPSGQKLLPNTLTDKF--YVHSEG-------TLDINGVTPKEGGLYTCIATNLVGAD 505
+ ++L + T+ F Y G L + V + G Y CI TN G++
Sbjct: 532 VWRKDSEILYDVDTENFVRYWQQAGEALEYTSILHLFNVNFTDEGKYQCIVTNHFGSN 589
Score = 87.4 bits (215), Expect = 4e-17
Identities = 105/451 (23%), Positives = 189/451 (41%), Gaps = 33/451 (7%)
Query: 74 LLLQTNNIAKIEYSTDFPVN-LTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELP 132
L +Q N I+K++ F +N + L+L NNL+ V + + L +Y+ +N + +
Sbjct: 244 LKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERIS 303
Query: 133 EKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEI 192
L EL +++N L+ + AF+GL L RL+L NR+ I F L NL+
Sbjct: 304 PDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQT 363
Query: 193 LMIGENPII-RIKDMN--FKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLI 249
L + N I I+D + F L +L L++ G + I A +GLE+LE + +N ++
Sbjct: 364 LDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIM 423
Query: 250 KVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLP 309
+ A + +LK L LN + + D L+ L NN +++ + L
Sbjct: 424 SIQENAFSQT-HLKELILNTSSL----LCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLA 478
Query: 310 -------DLRKIEATN--NPRLSYIHPNAFFRLPKLE------SLMLNSNALSALYHGTI 354
DL+ + P++ HP L + ++ + + +S ++
Sbjct: 479 GQSILNVDLKDFVCDDFLKPQIR-THPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDS 537
Query: 355 ESLPNLKEISIHSNPIRCDCVIRWMN-MNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFR 413
E L ++ + + + + + ++ N+ F + C+ F G N Q
Sbjct: 538 EILYDVDTENFVRYWQQAGEALEYTSILHLFNVNFTDEGKYQCIVTNHF-GSNYSQKAKL 596
Query: 414 DMMEICLPLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKF 473
+ E+ L P +L + G+ C A P P+I W G P +
Sbjct: 597 TVNEMPSFL----KTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTD-FPAARERRM 651
Query: 474 YVHSE-GTLDINGVTPKEGGLYTCIATNLVG 503
+V E I V ++ G+Y+C+A N G
Sbjct: 652 HVMPEDDVFFIANVKIEDMGIYSCMAQNTAG 682
Score = 52.8 bits (125), Expect = 1e-06
Identities = 44/147 (29%), Positives = 71/147 (48%), Gaps = 4/147 (2%)
Query: 224 LTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNM 283
LTEIP N+ +S N + ++ ALQ L+ LDL+ N I+ I+ F M
Sbjct: 109 LTEIPYFG-EPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRM 167
Query: 284 LHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNS 343
LK L ++N + ++++ DNL + N R+S I P F+LP L+ L L
Sbjct: 168 -QLKYLNLSN-NRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPK-IFKLPHLQFLELKR 224
Query: 344 NALSALYHGTIESLPNLKEISIHSNPI 370
N + + T + L +L+ + + N I
Sbjct: 225 NRIKIVEGLTFQGLDSLRSLKMQRNGI 251
Score = 34.3 bits (77), Expect = 0.41
Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 5/92 (5%)
Query: 434 VEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDK-FYVHSEGTLDINGVTPKEGG 492
V G C A P P + W G P +T++ F+ + L I ++ G
Sbjct: 707 VTRGETAVLQCIAGGSPAPRLNWTKDDG----PLLVTERHFFAAANQLLIIVDAGLEDAG 762
Query: 493 LYTCIATNLVGADLKSVMIKVDGSFPQDNNGS 524
YTCI +N +G + + + V S D++ S
Sbjct: 763 KYTCIMSNTLGTERGHIYLNVISSPNCDSSQS 794
>gi|205277468 leucine rich repeat containing 15 isoform a [Homo
sapiens]
Length = 587
Score = 127 bits (318), Expect = 5e-29
Identities = 109/374 (29%), Positives = 173/374 (46%), Gaps = 22/374 (5%)
Query: 2 KDMPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLL 61
K MPL+ H LL L A CP CTC AS V+C ++
Sbjct: 5 KAMPLK-HYLLLLVGCQAWGAGLAYHGCPSECTCS------------RASQVECTGARIV 51
Query: 62 TFPARLPANTQILLLQTNNIAKIEYSTDFPVN-LTGLDLSQNNLSSVTNINVKKMPQLLS 120
P LP N L + +I ++ S ++ L L + +N LS +T + + L
Sbjct: 52 AVPTPLPWNAMSLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRY 111
Query: 121 VYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN 180
+ L NKL LP L +L+ L ++ N L I P F NL L L+ N L+ I
Sbjct: 112 LSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIP 171
Query: 181 SKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLES 240
FD L L L +G+N + I F+ L NL+ L + LT+IP GL NL+
Sbjct: 172 DGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQE 231
Query: 241 ISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGI--NNMPELI 298
++ N++ + NL+ L L+ N I+++ F + L L + N++ EL
Sbjct: 232 LALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKEL- 290
Query: 299 SIDSLAV-DNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESL 357
SL + +P+LR++ +N +S + N F L +L+ L+L+ N +S + G L
Sbjct: 291 ---SLGIFGPMPNLRELWLYDN-HISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGL 346
Query: 358 PNLKEISIHSNPIR 371
L+E+S+H+N ++
Sbjct: 347 TELRELSLHTNALQ 360
Score = 121 bits (304), Expect = 2e-27
Identities = 101/367 (27%), Positives = 169/367 (46%), Gaps = 37/367 (10%)
Query: 69 ANTQILLLQTNNIAKI-EYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENK 127
+N + L L N++ I + + D V LT L+L +N+L+ ++ + + L + L EN+
Sbjct: 155 SNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENR 214
Query: 128 LTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDAL 187
LT++P L NLQEL + N + +SPG F HNL RL+L++N + + F L
Sbjct: 215 LTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQL 274
Query: 188 PNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNR 247
P L L + N + + F P+ NLR L + +++ +PDN L L+
Sbjct: 275 PQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQ-------- 326
Query: 248 LIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDN 307
L L++N I+ I G F+ + L+EL ++ L +D
Sbjct: 327 ----------------VLILSRNQISFISPGAFNGLTELRELSLHT-NALQDLDGNVFRM 369
Query: 308 LPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHS 367
L +L+ I NN RL + N F + L ++ L +N L L G + L L E+ ++
Sbjct: 370 LANLQNISLQNN-RLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLYD 428
Query: 368 NPIRCDCVI----RWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLI 423
NP RCD I W+ +N+ R C P +GQ++ ++ + + +P +
Sbjct: 429 NPWRCDSDILPLRNWLLLNQP--RLGTDTVPVCFSPANVRGQSLIIIN----VNVAVPSV 482
Query: 424 APESFPS 430
PS
Sbjct: 483 HVPEVPS 489
Score = 121 bits (303), Expect = 3e-27
Identities = 86/287 (29%), Positives = 145/287 (50%), Gaps = 4/287 (1%)
Query: 119 LSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQM 178
+S+ + +TEL E +S L L I N LS I+PGAF L +L L L +N+LQ+
Sbjct: 62 MSLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQV 121
Query: 179 INSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENL 238
+ F L +LE L++ N +++I+ +F NL+ L + G +L IPD A L L
Sbjct: 122 LPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGL 181
Query: 239 ESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGI-NNMPEL 297
++ N L + Q + NL+ L L +N + I G F +++L+EL + N L
Sbjct: 182 TKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGL 241
Query: 298 ISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESL 357
+S N +L+++ +NN +S + P+ F +LP+L L L N+L L G +
Sbjct: 242 LSPG--LFHNNHNLQRLYLSNN-HISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPM 298
Query: 358 PNLKEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQG 404
PNL+E+ ++ N I + N+ + + + + + + P F G
Sbjct: 299 PNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNG 345
>gi|18677767 leucine rich repeat containing 15 isoform b [Homo
sapiens]
Length = 581
Score = 126 bits (316), Expect = 8e-29
Identities = 100/347 (28%), Positives = 163/347 (46%), Gaps = 21/347 (6%)
Query: 29 CPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYST 88
CP CTC AS V+C ++ P LP N L + +I ++ S
Sbjct: 25 CPSECTCS------------RASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESP 72
Query: 89 DFPVN-LTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYI 147
++ L L + +N LS +T + + L + L NKL LP L +L+ L +
Sbjct: 73 FLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLL 132
Query: 148 NHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMN 207
+ N L I P F NL L L+ N L+ I FD L L L +G+N + I
Sbjct: 133 SSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRV 192
Query: 208 FKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDL 267
F+ L NL+ L + LT+IP GL NL+ ++ N++ + NL+ L L
Sbjct: 193 FQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYL 252
Query: 268 NKNPINRIRRGDFSNMLHLKELGI--NNMPELISIDSLAV-DNLPDLRKIEATNNPRLSY 324
+ N I+++ F + L L + N++ EL SL + +P+LR++ +N +S
Sbjct: 253 SNNHISQLPPSIFMQLPQLNRLTLFGNSLKEL----SLGIFGPMPNLRELWLYDN-HISS 307
Query: 325 IHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIR 371
+ N F L +L+ L+L+ N +S + G L L+E+S+H+N ++
Sbjct: 308 LPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQ 354
Score = 121 bits (304), Expect = 2e-27
Identities = 101/367 (27%), Positives = 169/367 (46%), Gaps = 37/367 (10%)
Query: 69 ANTQILLLQTNNIAKI-EYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENK 127
+N + L L N++ I + + D V LT L+L +N+L+ ++ + + L + L EN+
Sbjct: 149 SNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENR 208
Query: 128 LTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDAL 187
LT++P L NLQEL + N + +SPG F HNL RL+L++N + + F L
Sbjct: 209 LTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQL 268
Query: 188 PNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNR 247
P L L + N + + F P+ NLR L + +++ +PDN L L+
Sbjct: 269 PQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQ-------- 320
Query: 248 LIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDN 307
L L++N I+ I G F+ + L+EL ++ L +D
Sbjct: 321 ----------------VLILSRNQISFISPGAFNGLTELRELSLHT-NALQDLDGNVFRM 363
Query: 308 LPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHS 367
L +L+ I NN RL + N F + L ++ L +N L L G + L L E+ ++
Sbjct: 364 LANLQNISLQNN-RLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLYD 422
Query: 368 NPIRCDCVI----RWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLI 423
NP RCD I W+ +N+ R C P +GQ++ ++ + + +P +
Sbjct: 423 NPWRCDSDILPLRNWLLLNQP--RLGTDTVPVCFSPANVRGQSLIIIN----VNVAVPSV 476
Query: 424 APESFPS 430
PS
Sbjct: 477 HVPEVPS 483
Score = 121 bits (303), Expect = 3e-27
Identities = 86/287 (29%), Positives = 145/287 (50%), Gaps = 4/287 (1%)
Query: 119 LSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQM 178
+S+ + +TEL E +S L L I N LS I+PGAF L +L L L +N+LQ+
Sbjct: 56 MSLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQV 115
Query: 179 INSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENL 238
+ F L +LE L++ N +++I+ +F NL+ L + G +L IPD A L L
Sbjct: 116 LPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGL 175
Query: 239 ESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGI-NNMPEL 297
++ N L + Q + NL+ L L +N + I G F +++L+EL + N L
Sbjct: 176 TKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGL 235
Query: 298 ISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESL 357
+S N +L+++ +NN +S + P+ F +LP+L L L N+L L G +
Sbjct: 236 LSPG--LFHNNHNLQRLYLSNN-HISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPM 292
Query: 358 PNLKEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQG 404
PNL+E+ ++ N I + N+ + + + + + + P F G
Sbjct: 293 PNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNG 339
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 115 bits (287), Expect = 2e-25
Identities = 81/260 (31%), Positives = 132/260 (50%), Gaps = 9/260 (3%)
Query: 246 NRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAV 305
NR+ ++ A +++ NL L LN N I RI G F ++ +LK L + E+ SID A
Sbjct: 72 NRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKN-EIQSIDRQAF 130
Query: 306 DNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISI 365
L L ++ N ++ + P++F LPKLE L L++N ++ L GT L ++K + +
Sbjct: 131 KGLASLEQLYLHFN-QIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRL 189
Query: 366 HSNPIRCDCVIRWM-NMNKTNIRFMEPD-SLFCVDPPEFQGQNVRQVHFRDMMEICLPLI 423
SN + CDC I W+ ++ KT + C P QG++V + + + P I
Sbjct: 190 DSNTLHCDCEILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATI-TPEELNCERPRI 248
Query: 424 APESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDI 483
E P + +V +G+ V F CRA P+PEI W+ + + L + + +GTL I
Sbjct: 249 TSE--PQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNE--LSMKTDSRLNLLDDGTLMI 304
Query: 484 NGVTPKEGGLYTCIATNLVG 503
+ G+Y C+A N+ G
Sbjct: 305 QNTQETDQGIYQCMAKNVAG 324
Score = 65.5 bits (158), Expect = 2e-10
Identities = 85/371 (22%), Positives = 151/371 (40%), Gaps = 36/371 (9%)
Query: 145 LYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIK 204
L + N + I PGAF L NL L LN+N+++ I S F+ L NL+ L + +N I I
Sbjct: 67 LDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSID 126
Query: 205 DMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKF 264
FK L +L L + + + ++ L LE + ++NR+ + + ++K
Sbjct: 127 RQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKR 186
Query: 265 LDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSY 324
L L+ N ++ +L L +L + E + + A+ P R+I+ + ++
Sbjct: 187 LRLDSNTLH-----CDCEILWLADL-LKTYAESGNAQAAAICEYP--RRIQGRSVATITP 238
Query: 325 IHPNAFFRLPKLESLMLNSNALS---ALYHGTIESLPNLKEISIHSNPIRCDCVIRWMNM 381
N P++ S +++ S + E P + I + +N ++M
Sbjct: 239 EELNC--ERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNN--------NELSM 288
Query: 382 NKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDM------MEICLPLIAPESFPS----- 430
+ + D + + Q + Q +++ E+ L + P+
Sbjct: 289 KTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQP 348
Query: 431 -NLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVTPK 489
N V G V+ C AT P P I W T + LP + + + G L I V
Sbjct: 349 QNTEVLVGESVTLECSATGHPPPRISW-TRGDRTPLP--VDPRVNITPSGGLYIQNVVQG 405
Query: 490 EGGLYTCIATN 500
+ G Y C ATN
Sbjct: 406 DSGEYACSATN 416
Score = 62.8 bits (151), Expect = 1e-09
Identities = 50/185 (27%), Positives = 86/185 (46%), Gaps = 15/185 (8%)
Query: 17 TTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLL 76
T V A CP C C +TV C L L PA P T IL L
Sbjct: 24 TLAVVAQKPGAGCPSRCLCF-------------RTTVRCMHLLLEAVPAVAP-QTSILDL 69
Query: 77 QTNNIAKIEYSTDFPV-NLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKC 135
+ N I +I+ + NL L L+ N + + + + + L +YL +N++ + +
Sbjct: 70 RFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQA 129
Query: 136 LSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMI 195
L++L++LY++ N + T+ P +F L L RL L++NR+ + F+ L +++ L +
Sbjct: 130 FKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRL 189
Query: 196 GENPI 200
N +
Sbjct: 190 DSNTL 194
Score = 61.2 bits (147), Expect = 3e-09
Identities = 34/96 (35%), Positives = 50/96 (52%), Gaps = 6/96 (6%)
Query: 421 PLIAP--ESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSE 478
P + P S PS+ VE G+ V C + EP+P I W Q T + KF++ E
Sbjct: 521 PRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQV----TESGKFHISPE 576
Query: 479 GTLDINGVTPKEGGLYTCIATNLVGADLKSVMIKVD 514
G L IN V P + G Y C+A N +G+ S+++ V+
Sbjct: 577 GFLTINDVGPADAGRYECVARNTIGSASVSMVLSVN 612
Score = 59.3 bits (142), Expect = 1e-08
Identities = 34/121 (28%), Positives = 63/121 (52%)
Query: 97 LDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTIS 156
LDL N + + +++ L ++ L N++ +P +L NL+ LY+ N + +I
Sbjct: 67 LDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSID 126
Query: 157 PGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRS 216
AF GL +L +L+L+ N+++ ++ F LP LE L + N I + F L +++
Sbjct: 127 RQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKR 186
Query: 217 L 217
L
Sbjct: 187 L 187
Score = 58.2 bits (139), Expect = 3e-08
Identities = 39/133 (29%), Positives = 62/133 (46%)
Query: 116 PQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNR 175
PQ + L N++ E+ L NL L +N+N + I GAF L NL L+L N
Sbjct: 62 PQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNE 121
Query: 176 LQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGL 235
+Q I+ + F L +LE L + N I + +F+ L L L + +T + L
Sbjct: 122 IQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHL 181
Query: 236 ENLESISFYDNRL 248
E+++ + N L
Sbjct: 182 ESMKRLRLDSNTL 194
Score = 46.2 bits (108), Expect = 1e-04
Identities = 28/76 (36%), Positives = 38/76 (50%), Gaps = 4/76 (5%)
Query: 429 PSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVTP 488
P + V G V F C A P P I W T G +L ++ + V S GTL I+GV
Sbjct: 439 PQDRVVIEGQTVDFQCEAKGNPPPVIAW-TKGGSQL---SVDRRHLVLSSGTLRISGVAL 494
Query: 489 KEGGLYTCIATNLVGA 504
+ G Y C A N++G+
Sbjct: 495 HDQGQYECQAVNIIGS 510
>gi|149773484 leucine rich repeat and fibronectin type III domain
containing 1 [Homo sapiens]
Length = 771
Score = 114 bits (285), Expect = 3e-25
Identities = 123/533 (23%), Positives = 203/533 (38%), Gaps = 115/533 (21%)
Query: 117 QLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRL 176
+++ + L +N + + + + +++L L ++ N + ++ GAF L L LHL+SNRL
Sbjct: 66 RVVELRLTDNFIAAVRRRDFANMTSLVHLTLSRNTIGQVAAGAFADLRALRALHLDSNRL 125
Query: 177 QMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLE 236
+ L NL L++G N I R++ F L
Sbjct: 126 AEVRGDQLRGLGNLRHLILGNNQIRRVESAAFDAF-----------------------LS 162
Query: 237 NLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPE 296
+E + N L +P A+ ++VNL L L+ N I+ I G F
Sbjct: 163 TVEDLDLSYNNLEALPWEAVGQMVNLNTLTLDHNLIDHIAEGTFV--------------- 207
Query: 297 LISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIES 356
L L +++ T+N RL + P+ F L S GT
Sbjct: 208 ----------QLHKLVRLDMTSN-RLHKLPPDGLF----LRS------------QGTGPK 240
Query: 357 LPNLKEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMM 416
P +S NP+ C+C + W+ R D L PE ++ +F +
Sbjct: 241 PPTPLTVSFGGNPLHCNCELLWLR------RLTREDDLETCATPE----HLTDRYFWSIP 290
Query: 417 E---ICLPLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKF 473
E +C P + V G VS CRA +P+P ++W+ P G +LL N + +
Sbjct: 291 EEEFLCEPPLITRQAGGRALVVEGQAVSLRCRAVGDPEPVVHWVAPDG-RLLGN--SSRT 347
Query: 474 YVHSEGTLDINGVTPKEGGLYTCIATNLVGADLKSVMIKV-------------------- 513
V +GTLD+ T ++ G +TCIA+N G V + V
Sbjct: 348 RVRGDGTLDVTITTLRDSGTFTCIASNAAGEATAPVEVCVVPLPLMAPPPAAPPPLTEPG 407
Query: 514 --DGSFP-----QDNNGSLNIKIRDIQANSVLVSWKASSKILKSSVKWTAFVKTENSHAA 566
D + P D+ + ++ +NSVL+ W A + + + + +
Sbjct: 408 SSDIATPGRPGANDSAAERRLVAAELTSNSVLIRWPAQRPVPGIRMYQVQYNSSVDDSLV 467
Query: 567 QSARIPSDVKVYNLTHLNPSTEYKICI-----DIPTIYQKNR-KKCVNVTTKG 613
IPS + + + L Y +C+ D T R CV TT G
Sbjct: 468 Y-RMIPSTSQTFLVNDLAAGRAYDLCVLAVYDDGATALPATRVVGCVQFTTAG 519
Score = 54.7 bits (130), Expect = 3e-07
Identities = 55/208 (26%), Positives = 87/208 (41%), Gaps = 15/208 (7%)
Query: 29 CPRLCTCE-IRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYS 87
CP C C+ + P T + C GLL P + L L N IA +
Sbjct: 34 CPGRCICQNVAPTLT----------MLCAKTGLLFVPPAIDRRVVELRLTDNFIAAVR-R 82
Query: 88 TDFP--VNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQEL 145
DF +L L LS+N + V + L +++L+ N+L E+ L L NL+ L
Sbjct: 83 RDFANMTSLVHLTLSRNTIGQVAAGAFADLRALRALHLDSNRLAEVRGDQLRGLGNLRHL 142
Query: 146 YINHNLLSTISPGAFIG-LHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIK 204
+ +N + + AF L + L L+ N L+ + + + NL L + N I I
Sbjct: 143 ILGNNQIRRVESAAFDAFLSTVEDLDLSYNNLEALPWEAVGQMVNLNTLTLDHNLIDHIA 202
Query: 205 DMNFKPLINLRSLVIAGINLTEIPDNAL 232
+ F L L L + L ++P + L
Sbjct: 203 EGTFVQLHKLVRLDMTSNRLHKLPPDGL 230
>gi|4758460 glycoprotein V (platelet) [Homo sapiens]
Length = 560
Score = 113 bits (283), Expect = 5e-25
Identities = 104/367 (28%), Positives = 163/367 (44%), Gaps = 35/367 (9%)
Query: 29 CPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYST 88
CP C C R + S D + L P L T ILL S
Sbjct: 21 CPPACKCVFRD-------AAQCSGGDVARISALGLPTNL---THILLFGMGRGVLQSQSF 70
Query: 89 DFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYIN 148
L L +S +++S+V + +L ++ L NK+T LP L ++ L++L+++
Sbjct: 71 SGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLD 130
Query: 149 HNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKD--- 205
HN L I F L NL L LN N+L + + F L NL++L + N + +
Sbjct: 131 HNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLL 190
Query: 206 ----------MNFKPLINLRSLVIAGIN-LTE----------IPDNALVGLENLESISFY 244
++ L++L S ++ + LTE I A L NL S++
Sbjct: 191 GAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLS 250
Query: 245 DNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLA 304
N L +P NL L L +NP+ + F M L+EL +N +L ++ + A
Sbjct: 251 RNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNR-TQLRTLPAAA 309
Query: 305 VDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEIS 364
NL LR + T +PRLS + AF L +L+ L L+SN L+AL G + L L+++S
Sbjct: 310 FRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVS 369
Query: 365 IHSNPIR 371
+ N +R
Sbjct: 370 LRRNRLR 376
Score = 105 bits (261), Expect = 2e-22
Identities = 97/353 (27%), Positives = 154/353 (43%), Gaps = 52/353 (14%)
Query: 72 QILLLQTNNIAKIEYSTDFP-VNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTE 130
Q L++ ++I+ + T + L L LS+N ++ + + KM L ++L+ N L
Sbjct: 77 QRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLDHNALRG 136
Query: 131 LPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLL----------------------- 167
+ + +L NLQEL +N N L + F L NL
Sbjct: 137 IDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAKL 196
Query: 168 -RLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTE 226
RL L+SNRL ++S ++L L L N I I F L NL SL ++ +L
Sbjct: 197 ERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAF 256
Query: 227 IPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHL 286
+P + NL ++ ++N L ++P V ++ L+ L LN+ + + F N+ L
Sbjct: 257 LPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRL 316
Query: 287 KELGINNMPEL----------------ISIDSLAVDNLPD--------LRKIEATNNPRL 322
+ LG+ P L +++ S + LPD LR++ N RL
Sbjct: 317 RYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRN-RL 375
Query: 323 SYIHPNAFFR-LPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDC 374
+ P A FR L LES+ L+ N L L +LP L E+ + N RCDC
Sbjct: 376 RAL-PRALFRNLSSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHNSWRCDC 427
>gi|27363458 leucine rich repeat and fibronectin type III domain
containing 4 [Homo sapiens]
Length = 635
Score = 112 bits (279), Expect = 2e-24
Identities = 113/441 (25%), Positives = 186/441 (42%), Gaps = 59/441 (13%)
Query: 193 LMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVP 252
L + +N I + +F+ + L L ++ +T I A LE+L S+ NRL+++
Sbjct: 53 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 112
Query: 253 HVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKE---LGINNMPELISIDSLAVDNLP 309
+L+ VNL+ L L+ N + RI G F + L E L NN+ + + + +P
Sbjct: 113 TGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQ---VPWAGIGAMP 169
Query: 310 DLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTI-------ESLPNLKE 362
L + +N + + P AF +L +L L L SN L+ L + E+ P
Sbjct: 170 ALHTLNLDHN-LIDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLV 228
Query: 363 ISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSL-FCVDPPEFQGQNVRQVHFRDMMEICLP 421
+S NP+ C+C + W+ R PD L C PP G+ V P
Sbjct: 229 LSFSGNPLHCNCELLWLR------RLARPDDLETCASPPGLAGRYFWAVP-EGEFSCEPP 281
Query: 422 LIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTL 481
LIA + L V G + CRA +P P ++W+ P +L+ N+ + + GTL
Sbjct: 282 LIARHT--QRLWVLEGQRATLRCRALGDPAPTMHWVGPD-DRLVGNSSRARAF--PNGTL 336
Query: 482 DINGVTPKEGGLYTCIATNLVGADLKSVMIKV-----------DGSFP------------ 518
+I + G YTCIATN G V ++V +G P
Sbjct: 337 EIGVTGAGDAGGYTCIATNPAGEATARVELRVLALPHGGNSSAEGGRPGPSDIAASARTA 396
Query: 519 QDNNGSLN----IKIRDIQANSVLVSWKASSKILKSSVKWTAFVKTENSHAAQSAR--IP 572
+ G+L +++ ++ A S LVSW + W ++ +S +P
Sbjct: 397 AEGEGTLESEPAVQVTEVTATSGLVSWGPGR---PADPVWMFQIQYNSSEDETLIYRIVP 453
Query: 573 SDVKVYNLTHLNPSTEYKICI 593
+ + L HL P +Y +C+
Sbjct: 454 ASSHHFLLKHLVPGADYDLCL 474
Score = 58.5 bits (140), Expect = 2e-08
Identities = 62/208 (29%), Positives = 91/208 (43%), Gaps = 15/208 (7%)
Query: 29 CPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYST 88
CP C C+ ++ ST+ C GLL P + T L L N I +
Sbjct: 17 CPLPCVCQ--------NLSESLSTL-CAHRGLLFVPPNVDRRTVELRLADNFIQALG-PP 66
Query: 89 DFPVNLTGL---DLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQEL 145
DF N+TGL LS+N ++ + + L S++L+ N+L EL L NLQ L
Sbjct: 67 DFR-NMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHL 125
Query: 146 YINHNLLSTISPGAFIG-LHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIK 204
++ N L I+PGAF L +L L L+ N L+ + A+P L L + N I +
Sbjct: 126 ILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALP 185
Query: 205 DMNFKPLINLRSLVIAGINLTEIPDNAL 232
F L L L + L + + L
Sbjct: 186 PGAFAQLGQLSRLDLTSNRLATLAPDPL 213
>gi|40255157 leucine-rich repeats and immunoglobulin-like domains 3
isoform 2 [Homo sapiens]
Length = 1119
Score = 111 bits (278), Expect = 2e-24
Identities = 108/470 (22%), Positives = 198/470 (42%), Gaps = 36/470 (7%)
Query: 47 YMEASTVDCNDLGLLTFPARLPA-NTQILLLQTNNIAKIE--YSTDFPVNLTGLDLSQNN 103
+ T+D + + PA + L L +N + +E Y + L L L++N
Sbjct: 144 FQSLETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNR 203
Query: 104 LSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGL 163
+S++ + K+PQL + L NK+ + L L+ L + N ++ + GAF GL
Sbjct: 204 ISAIPP-KMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGL 262
Query: 164 HNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGIN 223
N+ L L+ N L I W L L+ L + +N I RI ++ L L + +
Sbjct: 263 SNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNH 322
Query: 224 LTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNM 283
L+ + D++ +GL L ++ +NR+ + A + + +LK LDL N I+
Sbjct: 323 LSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEIS---------- 372
Query: 284 LHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNS 343
I +M + A L LR++ N R+ I AF L LE L L+
Sbjct: 373 -----WTIEDM-------NGAFSGLDKLRRLILQGN-RIRSITKKAFTGLDALEHLDLSD 419
Query: 344 NALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQ 403
NA+ +L + L+++ ++++ + CDC ++W+ F + C P +
Sbjct: 420 NAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLK 479
Query: 404 GQNVRQVHFRDMMEICLPLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQK 463
G+++ V + P P + GS +SF C A + + + +
Sbjct: 480 GRSIFAVSPDGFVCDDFPKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNE 539
Query: 464 LLPNTLTDKF-YVHSEG--------TLDINGVTPKEGGLYTCIATNLVGA 504
LL + + + ++ ++G L + V G Y C+ +N G+
Sbjct: 540 LLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKYQCVISNHFGS 589
Score = 85.9 bits (211), Expect = 1e-16
Identities = 113/496 (22%), Positives = 196/496 (39%), Gaps = 62/496 (12%)
Query: 69 ANTQILL-LQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENK 127
ANT ++L L N I+ I L L+L++N + +V + + + L S+ ++ N
Sbjct: 191 ANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNG 250
Query: 128 LTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN-SKW--- 183
+T+L + LSN++ L ++HN L+ I+ G GL L LHL+ N + I+ W
Sbjct: 251 VTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFC 310
Query: 184 --------------------FDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGIN 223
F L L L IG N + I D F+ L +L++L +
Sbjct: 311 QKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNE 370
Query: 224 LT---EIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDF 280
++ E + A GL+ L + NR+ + A + L+ LDL+ N I ++ F
Sbjct: 371 ISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAF 430
Query: 281 SNMLHLKELGINN-----------MPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNA 329
S M L++L +N +P+ ++ ++ + + + P+
Sbjct: 431 SQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDG 490
Query: 330 FFR----------LPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIR-W 378
F P+ +S + SN LS + S + N + D + +
Sbjct: 491 FVCDDFPKPQITVQPETQSAIKGSN-LSFICSAASSSDSPMTFAWKKDNELLHDAEMENY 549
Query: 379 MNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQV----HFRDMMEICLPLIAP--ESF---P 429
++ ME ++ + EF + Q HF + L SF P
Sbjct: 550 AHLRAQGGEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTP 609
Query: 430 SNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSE-GTLDINGVTP 488
+L + AG+ C A P P+I W G P + +V E I V
Sbjct: 610 MDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTD-FPAARERRMHVMPEDDVFFIVDVKI 668
Query: 489 KEGGLYTCIATNLVGA 504
++ G+Y+C A N G+
Sbjct: 669 EDIGVYSCTAQNSAGS 684
>gi|209862903 leucine-rich repeats and immunoglobulin-like domains 3
isoform 1 [Homo sapiens]
Length = 1059
Score = 111 bits (278), Expect = 2e-24
Identities = 108/470 (22%), Positives = 198/470 (42%), Gaps = 36/470 (7%)
Query: 47 YMEASTVDCNDLGLLTFPARLPA-NTQILLLQTNNIAKIE--YSTDFPVNLTGLDLSQNN 103
+ T+D + + PA + L L +N + +E Y + L L L++N
Sbjct: 84 FQSLETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNR 143
Query: 104 LSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGL 163
+S++ + K+PQL + L NK+ + L L+ L + N ++ + GAF GL
Sbjct: 144 ISAIPP-KMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGL 202
Query: 164 HNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGIN 223
N+ L L+ N L I W L L+ L + +N I RI ++ L L + +
Sbjct: 203 SNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNH 262
Query: 224 LTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNM 283
L+ + D++ +GL L ++ +NR+ + A + + +LK LDL N I+
Sbjct: 263 LSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEIS---------- 312
Query: 284 LHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNS 343
I +M + A L LR++ N R+ I AF L LE L L+
Sbjct: 313 -----WTIEDM-------NGAFSGLDKLRRLILQGN-RIRSITKKAFTGLDALEHLDLSD 359
Query: 344 NALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQ 403
NA+ +L + L+++ ++++ + CDC ++W+ F + C P +
Sbjct: 360 NAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLK 419
Query: 404 GQNVRQVHFRDMMEICLPLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQK 463
G+++ V + P P + GS +SF C A + + + +
Sbjct: 420 GRSIFAVSPDGFVCDDFPKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNE 479
Query: 464 LLPNTLTDKF-YVHSEG--------TLDINGVTPKEGGLYTCIATNLVGA 504
LL + + + ++ ++G L + V G Y C+ +N G+
Sbjct: 480 LLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKYQCVISNHFGS 529
Score = 85.9 bits (211), Expect = 1e-16
Identities = 113/496 (22%), Positives = 196/496 (39%), Gaps = 62/496 (12%)
Query: 69 ANTQILL-LQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENK 127
ANT ++L L N I+ I L L+L++N + +V + + + L S+ ++ N
Sbjct: 131 ANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNG 190
Query: 128 LTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN-SKW--- 183
+T+L + LSN++ L ++HN L+ I+ G GL L LHL+ N + I+ W
Sbjct: 191 VTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFC 250
Query: 184 --------------------FDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGIN 223
F L L L IG N + I D F+ L +L++L +
Sbjct: 251 QKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNE 310
Query: 224 LT---EIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDF 280
++ E + A GL+ L + NR+ + A + L+ LDL+ N I ++ F
Sbjct: 311 ISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAF 370
Query: 281 SNMLHLKELGINN-----------MPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNA 329
S M L++L +N +P+ ++ ++ + + + P+
Sbjct: 371 SQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDG 430
Query: 330 FFR----------LPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIR-W 378
F P+ +S + SN LS + S + N + D + +
Sbjct: 431 FVCDDFPKPQITVQPETQSAIKGSN-LSFICSAASSSDSPMTFAWKKDNELLHDAEMENY 489
Query: 379 MNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQV----HFRDMMEICLPLIAP--ESF---P 429
++ ME ++ + EF + Q HF + L SF P
Sbjct: 490 AHLRAQGGEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTP 549
Query: 430 SNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSE-GTLDINGVTP 488
+L + AG+ C A P P+I W G P + +V E I V
Sbjct: 550 MDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTD-FPAARERRMHVMPEDDVFFIVDVKI 608
Query: 489 KEGGLYTCIATNLVGA 504
++ G+Y+C A N G+
Sbjct: 609 EDIGVYSCTAQNSAGS 624
>gi|34577057 fibronectin leucine rich transmembrane protein 1 [Homo
sapiens]
Length = 674
Score = 110 bits (276), Expect = 3e-24
Identities = 142/600 (23%), Positives = 241/600 (40%), Gaps = 131/600 (21%)
Query: 4 MPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTF 63
M LR + L + + V CP +C C+ + CND GL +
Sbjct: 29 MDLRDWLFLCYGLIAFLTEVIDSTTCPSVCRCD-------------NGFIYCNDRGLTSI 75
Query: 64 PARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYL 123
PA +P + L LQ N I N G+ +L + N+ V +YL
Sbjct: 76 PADIPDDATTLYLQNNQI-----------NNAGIP---QDLKTKVNVQV--------IYL 113
Query: 124 EENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKW 183
EN L E P ++ +L+EL++ N + TI+ + + L +LHL+ N + ++
Sbjct: 114 YENDLDEFP---INLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVS--- 167
Query: 184 FDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLEN-LESIS 242
I++ F L+ L ++ +L+ IP GL + LE +
Sbjct: 168 -------------------IEEDAFADSKQLKLLFLSRNHLSSIPS----GLPHTLEELR 204
Query: 243 FYDNRLIKVPHVALQKVVNLKFLDLNKNPI--NRIRRGDFSNMLHLKELGINNMPELISI 300
DNR+ +P A + + +L+ L L+ N + RI FS + +L EL +
Sbjct: 205 LDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVR------- 257
Query: 301 DSLAVD--NLPD--LRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIES 356
+SLA NLP L+K+ +N +S+I N ++ +LE L L++N L+ L G +
Sbjct: 258 NSLAAPPLNLPSAHLQKLYLQDNA-ISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDD 316
Query: 357 LPNLKEISIHSNPIRCDCVIRWM-NMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDM 415
L NL ++ + +NP C C + W+ + K + L C P + +G ++ +
Sbjct: 317 LGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDI--TSE 374
Query: 416 MEICLPLIAPESFPSN--LNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKF 473
M+ C E+ P N A + S H AT TP G
Sbjct: 375 MDECF-----ETGPQGGVANAAAKTTASNHASAT----------TPQG------------ 407
Query: 474 YVHSEGTLDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQ 533
+ + K GL L +++ M DG+ +L I ++ +
Sbjct: 408 --------SLFTLKAKRPGL------RLPDSNIDYPMATGDGA------KTLAIHVKALT 447
Query: 534 ANSVLVSWKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICI 593
A+S+ ++WKA+ + W + + + D Y LT L P + Y IC+
Sbjct: 448 ADSIRITWKATLPASSFRLSWLRLGHSPAVGSITETLVQGDKTEYLLTALEPKSTYIICM 507
>gi|194440719 chondroadherin-like [Homo sapiens]
Length = 762
Score = 110 bits (275), Expect = 4e-24
Identities = 108/385 (28%), Positives = 158/385 (41%), Gaps = 72/385 (18%)
Query: 29 CPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYST 88
CPR C C E+ C GL P P++TQ+L
Sbjct: 396 CPRACVC-----------VPESRHSSCEGCGLQAVPRGFPSDTQLL-------------- 430
Query: 89 DFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYIN 148
DL +N+ SV + L+S++L+ + EL L+ L L LY++
Sbjct: 431 ---------DLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLS 481
Query: 149 HNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNF 208
N L+ +S A G L L+L NR + ALP+L L + +N + R+ +
Sbjct: 482 DNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDL 541
Query: 209 KPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLN 268
LR + ++G +TE+ AL LE + N+L +VP AL+ + L L L+
Sbjct: 542 GRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLS 601
Query: 269 KNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPN 328
NP+ +R G F P S+ L + N+ L I P
Sbjct: 602 GNPLRALRDGAF-------------QPVGRSLQHLFL------------NSSGLEQICPG 636
Query: 329 AFFRL-PKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVI----RWMNMNK 383
AF L P L+SL L N L AL + SL L+ I + SNP CDC + RW +
Sbjct: 637 AFSGLGPGLQSLHLQKNQLRAL--PALPSLSQLELIDLSSNPFHCDCQLLPLHRW--LTG 692
Query: 384 TNIRFMEPDSLFCVDPPEFQGQNVR 408
N+R C PP +GQ V+
Sbjct: 693 LNLRV----GATCATPPNARGQRVK 713
Score = 89.0 bits (219), Expect = 1e-17
Identities = 97/375 (25%), Positives = 149/375 (39%), Gaps = 66/375 (17%)
Query: 4 MPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTF 63
+PL + +L+ L + QA ++ CP+ C C+ V C L
Sbjct: 10 VPLVLPLLVLLLLAPARQAAAQR--CPQACICD-----------NSRRHVACRYQNLTEV 56
Query: 64 PARLPANTQILLLQTNNIAKIEYSTDFPV-NLTGLDLSQNNLSSVTNINVKKMPQLLSVY 122
P +P TQ L LQ N + I + V +LT LDL + V + + +LL +
Sbjct: 57 PDAIPELTQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLN 116
Query: 123 LEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSK 182
L N L ELP++ L GL +L RL L N L+ +
Sbjct: 117 LASNHLRELPQEALD------------------------GLGSLRRLELEGNALEELRPG 152
Query: 183 WFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESIS 242
F AL L L + N ++ + M F+ L+ +R L ++ L+ + AL GL L +S
Sbjct: 153 TFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLS 212
Query: 243 FYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDS 302
+ N L +P L + L L+L NP+ D
Sbjct: 213 LHHNELQALPGPVLSQARGLARLELGHNPLTYAGEED----------------------G 250
Query: 303 LAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKE 362
LA LP LR++ + L + P AF P+L +L L N L L ++ L+
Sbjct: 251 LA---LPGLREL-LLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTL--PPLQGPGQLRR 304
Query: 363 ISIHSNPIRCDCVIR 377
+ + NP+ C C R
Sbjct: 305 LRLQGNPLWCGCQAR 319
>gi|86990456 leucine rich repeat transmembrane neuronal 1 [Homo
sapiens]
Length = 522
Score = 109 bits (273), Expect = 8e-24
Identities = 86/313 (27%), Positives = 144/313 (46%), Gaps = 35/313 (11%)
Query: 121 VYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN 180
+Y E LTE P LS L L + +N LS + G F GL L L+L+ N + +
Sbjct: 50 LYCEALNLTEAPHN----LSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQ 105
Query: 181 SKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLES 240
F L ++ L + N I ++ + F+P+ NLRS+ ++ L + + GL L +
Sbjct: 106 GDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTT 165
Query: 241 ISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGIN-------- 292
+ N + VP Q +LKFLD+ N + + R F+ + L EL +
Sbjct: 166 LHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVN 225
Query: 293 --NMPELISIDSL------------AVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLES 338
+ P LIS+ SL ++D + +L K++ + N + Y+ P+ F +P L+S
Sbjct: 226 FAHFPRLISLHSLCLRRNKVAIVVSSLDWVWNLEKMDLSGN-EIEYMEPHVFETVPHLQS 284
Query: 339 LMLNSNALSALYHGTIESLPNLKEISIHSNPIRCD----CVIRWMNMNKTNIRFMEPDSL 394
L L+SN L+ + + S +L I++ N C + W+N N + +L
Sbjct: 285 LQLDSNRLTYIEPRILNSWKSLTSITLAGNLWDCGRNVCALASWLN----NFQGRYDGNL 340
Query: 395 FCVDPPEFQGQNV 407
C P QG++V
Sbjct: 341 QCASPEYAQGEDV 353
Score = 39.7 bits (91), Expect = 0.010
Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 3/98 (3%)
Query: 56 NDLGLLTFPARLPANTQI--LLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVK 113
NDL + F A P + L L+ N +A + S D+ NL +DLS N + + +
Sbjct: 219 NDLVKVNF-AHFPRLISLHSLCLRRNKVAIVVSSLDWVWNLEKMDLSGNEIEYMEPHVFE 277
Query: 114 KMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNL 151
+P L S+ L+ N+LT + + L+ +L + + NL
Sbjct: 278 TVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGNL 315
>gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo
sapiens]
Length = 581
Score = 109 bits (272), Expect = 1e-23
Identities = 81/314 (25%), Positives = 142/314 (45%), Gaps = 34/314 (10%)
Query: 121 VYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN 180
VY E KL E+P + L + +N L + F GL+ L L+L+ N + I+
Sbjct: 45 VYCESQKLQEIPSSISAGCLGLS---LRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNID 101
Query: 181 SKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLES 240
F+ + L+ L++ N I + F+P+ NLR+L ++ L + GL L S
Sbjct: 102 ENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLS 161
Query: 241 ISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINN------- 293
+ N L +P Q NL+ LDL N I + R F+ M+ LKEL + +
Sbjct: 162 LHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLN 221
Query: 294 ---MPELISIDSLAVD-------------NLPDLRKIEATNNPRLSYIHPNAFFRLPKLE 337
P L+S+ +L + L++++ + N ++ P+ F +P L+
Sbjct: 222 LALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQ 281
Query: 338 SLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCD----CVIRWMNMNKTNIRFMEPDS 393
L L+SN L+ + ++S +L +IS+ N C ++ W+ + + + ++
Sbjct: 282 RLNLDSNKLTFIGQEILDSWISLNDISLAGNIWECSRNICSLVNWLK----SFKGLRENT 337
Query: 394 LFCVDPPEFQGQNV 407
+ C P E QG NV
Sbjct: 338 IICASPKELQGVNV 351
>gi|7019381 fibronectin leucine rich transmembrane protein 2 [Homo
sapiens]
Length = 660
Score = 109 bits (272), Expect = 1e-23
Identities = 103/405 (25%), Positives = 176/405 (43%), Gaps = 88/405 (21%)
Query: 19 LVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQT 78
L V K + CP +C C+ + V CN+ L + P +P +L L
Sbjct: 26 LYSQVSKLLACPSVCRCD-------------RNFVYCNERSLTSVPLGIPEGVTVLYLHN 72
Query: 79 NNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSE 138
N I N G +N+ SV +VYL N+L E P ++
Sbjct: 73 NQI-----------NNAGFPAELHNVQSVH-----------TVYLYGNQLDEFP---MNL 107
Query: 139 LSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGEN 198
N++ L++ N + TIS A L L LHL+ N + +
Sbjct: 108 PKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVG------------------ 149
Query: 199 PIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLE-NLESISFYDNRLIKVPHVALQ 257
++D F+ I+L+ L ++ +L+ +P VGL +L+ + +NR+ + +A Q
Sbjct: 150 ----VEDGAFREAISLKLLFLSKNHLSSVP----VGLPVDLQELRVDENRIAVISDMAFQ 201
Query: 258 KVVNLKFLDLNKNPINR--IRRGDFSNMLHLKELGI--NNMPELISIDSLAVDNLPDLRK 313
+ +L+ L ++ N + I G FS++ LKE I N++ S +LP
Sbjct: 202 NLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSL-------SHPPPDLPGTHL 254
Query: 314 IEA-TNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRC 372
I + ++++I AF L KLE L +++N L L G ++L NLK+++ +NP C
Sbjct: 255 IRLYLQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLSNLKQLTARNNPWFC 314
Query: 373 DCVIRWMN------MNKTNIRFMEPDSLFCVDPPEFQGQNVRQVH 411
DC I+W+ + N+R C P + +G VR+++
Sbjct: 315 DCSIKWVTEWLKYIPSSLNVR-----GFMCQGPEQVRGMAVRELN 354
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,699,370
Number of Sequences: 37866
Number of extensions: 1199742
Number of successful extensions: 7013
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 292
Number of HSP's successfully gapped in prelim test: 246
Number of HSP's that attempted gapping in prelim test: 2817
Number of HSP's gapped (non-prelim): 2309
length of query: 708
length of database: 18,247,518
effective HSP length: 109
effective length of query: 599
effective length of database: 14,120,124
effective search space: 8457954276
effective search space used: 8457954276
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.