Guide to the Human Genome
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Search of human proteins with 153792186

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153792186 claudin 7 [Homo sapiens]
         (211 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153792186 claudin 7 [Homo sapiens]                                 429   e-120
gi|10863887 claudin 1 [Homo sapiens]                                  276   1e-74
gi|183979975 claudin 19 isoform b [Homo sapiens]                      249   1e-66
gi|183979973 claudin 19 isoform a [Homo sapiens]                      245   2e-65
gi|4502877 claudin 4 [Homo sapiens]                                   209   1e-54
gi|4502875 claudin 3 [Homo sapiens]                                   208   2e-54
gi|11141861 claudin 9 [Homo sapiens]                                  205   2e-53
gi|153792768 claudin 6 [Homo sapiens]                                 198   2e-51
gi|195947374 claudin 5 [Homo sapiens]                                 194   4e-50
gi|195947372 claudin 5 [Homo sapiens]                                 194   4e-50
gi|225703142 claudin 14 [Homo sapiens]                                184   4e-47
gi|21536294 claudin 14 [Homo sapiens]                                 184   4e-47
gi|225703138 claudin 14 [Homo sapiens]                                184   4e-47
gi|6912314 claudin 14 [Homo sapiens]                                  184   4e-47
gi|225703140 claudin 14 [Homo sapiens]                                184   4e-47
gi|40788011 claudin 8 [Homo sapiens]                                  184   6e-47
gi|6912316 claudin 17 [Homo sapiens]                                  174   5e-44
gi|9966781 claudin 2 [Homo sapiens]                                   167   6e-42
gi|47716519 claudin 20 [Homo sapiens]                                 162   3e-40
gi|5921465 claudin 10 isoform b [Homo sapiens]                        158   4e-39
gi|7656981 claudin 15 [Homo sapiens]                                  154   7e-38
gi|33598916 claudin 10 isoform a [Homo sapiens]                       145   2e-35
gi|50345279 claudin 18 isoform 2 [Homo sapiens]                       141   4e-34
gi|7705961 claudin 18 isoform 1 [Homo sapiens]                        140   6e-34
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]                129   2e-30
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]                   129   2e-30
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]                127   7e-30
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]                127   7e-30
gi|162417973 claudin 22 [Homo sapiens]                                127   9e-30
gi|157820127 claudin-like [Homo sapiens]                              104   5e-23

>gi|153792186 claudin 7 [Homo sapiens]
          Length = 211

 Score =  429 bits (1102), Expect = e-120
 Identities = 211/211 (100%), Positives = 211/211 (100%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG
Sbjct: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
           MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM
Sbjct: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
           GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA
Sbjct: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180

Query: 181 LLSCSCPGNESKAGYRVPRSYPKSNSSKEYV 211
           LLSCSCPGNESKAGYRVPRSYPKSNSSKEYV
Sbjct: 181 LLSCSCPGNESKAGYRVPRSYPKSNSSKEYV 211


>gi|10863887 claudin 1 [Homo sapiens]
          Length = 211

 Score =  276 bits (705), Expect = 1e-74
 Identities = 129/213 (60%), Positives = 169/213 (79%), Gaps = 4/213 (1%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           MAN+GLQLLGF +A LGW+G +  TA+PQW++ SYAGDNI+TAQAMY+GLWM CV+QSTG
Sbjct: 1   MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
            + CK++DS+L LS+ LQATRALMVV ++LG +A+FVAT+GMKC +C  DD+V+K R+A+
Sbjct: 61  QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
            GG IF++AGLA LVA +WYG++IV +FY+P+ P N +YEFG A+F GWA ++L +LGGA
Sbjct: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180

Query: 181 LLSCSCPGNESKAGYRVPRSYPK--SNSSKEYV 211
           LL CSCP       Y  PR YPK   +S K+YV
Sbjct: 181 LLCCSCP--RKTTSYPTPRPYPKPAPSSGKDYV 211


>gi|183979975 claudin 19 isoform b [Homo sapiens]
          Length = 211

 Score =  249 bits (636), Expect = 1e-66
 Identities = 113/211 (53%), Positives = 153/211 (72%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           MANSGLQLLG+ +AL GWVG++A TA+PQW+ SSYAGD IITA  +Y+GLWM C +QSTG
Sbjct: 1   MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
            + CK+YDS+LAL   +Q+ RALMVV+++LGF+AM ++ +GMKCTR G  + + K R+A+
Sbjct: 61  QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
            GG +FI+AGL  L A SWY   +  +F+NP  P N +YEFGPA+F+GWA + L +LGG+
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180

Query: 181 LLSCSCPGNESKAGYRVPRSYPKSNSSKEYV 211
            L C+CP  E       P     S +++EYV
Sbjct: 181 FLCCTCPEPERPNSSPQPYRPGPSAAAREYV 211


>gi|183979973 claudin 19 isoform a [Homo sapiens]
          Length = 224

 Score =  245 bits (626), Expect = 2e-65
 Identities = 108/190 (56%), Positives = 145/190 (76%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           MANSGLQLLG+ +AL GWVG++A TA+PQW+ SSYAGD IITA  +Y+GLWM C +QSTG
Sbjct: 1   MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
            + CK+YDS+LAL   +Q+ RALMVV+++LGF+AM ++ +GMKCTR G  + + K R+A+
Sbjct: 61  QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
            GG +FI+AGL  L A SWY   +  +F+NP  P N +YEFGPA+F+GWA + L +LGG+
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180

Query: 181 LLSCSCPGNE 190
            L C+CP  E
Sbjct: 181 FLCCTCPEPE 190


>gi|4502877 claudin 4 [Homo sapiens]
          Length = 209

 Score =  209 bits (533), Expect = 1e-54
 Identities = 93/208 (44%), Positives = 145/208 (69%), Gaps = 4/208 (1%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           MA+ GLQ++G ++A+LGW+ ++ C A+P W+++++ G NI+T+Q +++GLWM+CV QSTG
Sbjct: 1   MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
            M CK+YDS+LAL   LQA RAL+++S+++  L + ++ +G KCT C  +D+  KA+  +
Sbjct: 61  QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNC-LEDESAKAKTMI 119

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
             G++F++AGL  +V  SW  H I+ DFYNPL+ +  K E G ++++GWA S L++LGG 
Sbjct: 120 VAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGG 179

Query: 181 LLSCSCPGNESK---AGYRVPRSYPKSN 205
           LL C+CP    K   A Y   RS   SN
Sbjct: 180 LLCCNCPPRTDKPYSAKYSAARSAAASN 207


>gi|4502875 claudin 3 [Homo sapiens]
          Length = 220

 Score =  208 bits (530), Expect = 2e-54
 Identities = 97/201 (48%), Positives = 139/201 (69%), Gaps = 6/201 (2%)

Query: 5   GLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSC 64
           GL++ G ++A+LGW+G + C A+P W++S++ G NIIT+Q +++GLWM+CV QSTG M C
Sbjct: 4   GLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQC 63

Query: 65  KMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGGI 124
           K+YDS+LAL   LQA RAL+VV+++L    + VA +G +CT C  DD   KA+I +  G+
Sbjct: 64  KVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDD-TAKAKITIVAGV 122

Query: 125 IFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGALLSC 184
           +F++A L  LV  SW  + I+ DFYNP++P   K E G  +++GWA +AL +LGGALL C
Sbjct: 123 LFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCC 182

Query: 185 SCPGNE-----SKAGYRVPRS 200
           SCP  E     +K  Y  PRS
Sbjct: 183 SCPPREKKYTATKVVYSAPRS 203


>gi|11141861 claudin 9 [Homo sapiens]
          Length = 217

 Score =  205 bits (522), Expect = 2e-53
 Identities = 96/218 (44%), Positives = 147/218 (67%), Gaps = 8/218 (3%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           MA++GL+LLG ++A+LGW+G +   A+P W+++++ G++I+ AQ +++GLWM CV QSTG
Sbjct: 1   MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
            M CK+YDS+LAL   LQA RAL V++L+L  L + VA  G +CT C  +D+  KARI +
Sbjct: 61  QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTC-VEDEGAKARIVL 119

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
             G+I ++AG+  L+   W  H I+ DFYNPL+   +K E G ++++GWA +AL++LGG 
Sbjct: 120 TAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGG 179

Query: 181 LLSCSCPGNE------SKAGYRVP-RSYPKSNSSKEYV 211
           LL C+CP  +       + GY +P RS       ++YV
Sbjct: 180 LLCCTCPPPQVERPRGPRLGYSIPSRSGASGLDKRDYV 217


>gi|153792768 claudin 6 [Homo sapiens]
          Length = 220

 Score =  198 bits (504), Expect = 2e-51
 Identities = 96/220 (43%), Positives = 143/220 (65%), Gaps = 17/220 (7%)

Query: 1   MANSGLQLLGFSMALLGWV-GLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQST 59
           MA++G+Q+LG  + LLGWV GLV+C A+P W+++++ G++I+ AQ +++GLWM CV QST
Sbjct: 1   MASAGMQILGVVLTLLGWVNGLVSC-ALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQST 59

Query: 60  GMMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIA 119
           G M CK+YDS+LAL   LQA RAL V++L++    + V   G KCT C  ++K  KAR+ 
Sbjct: 60  GQMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTC-VEEKDSKARLV 118

Query: 120 MGGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGG 179
           +  GI+F+++G+  L+   W  H I+ DFYNPL+    K E G ++++GWA S L++LGG
Sbjct: 119 LTSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGG 178

Query: 180 ALLSCSCP--GNESKAGY------------RVPRSYPKSN 205
            LL C+CP  G++  + Y            R P  YP  N
Sbjct: 179 GLLCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKN 218


>gi|195947374 claudin 5 [Homo sapiens]
          Length = 303

 Score =  194 bits (494), Expect = 4e-50
 Identities = 87/184 (47%), Positives = 128/184 (69%), Gaps = 1/184 (0%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           M ++ L++LG  + L+GW GL+    +P WQ++++   NI+TAQ  +KGLWM CV QSTG
Sbjct: 86  MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
            M CK+YDSVLALS  +QA RAL V +++L F+A+FV   G +CT C       KAR+A+
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPA-KARVAL 204

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
            GG++++  GL ALV   W+ + +V +FY+P +P + KYE G A++IGWA +AL+++GG 
Sbjct: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264

Query: 181 LLSC 184
           LL C
Sbjct: 265 LLCC 268


>gi|195947372 claudin 5 [Homo sapiens]
          Length = 303

 Score =  194 bits (494), Expect = 4e-50
 Identities = 87/184 (47%), Positives = 128/184 (69%), Gaps = 1/184 (0%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           M ++ L++LG  + L+GW GL+    +P WQ++++   NI+TAQ  +KGLWM CV QSTG
Sbjct: 86  MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
            M CK+YDSVLALS  +QA RAL V +++L F+A+FV   G +CT C       KAR+A+
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPA-KARVAL 204

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
            GG++++  GL ALV   W+ + +V +FY+P +P + KYE G A++IGWA +AL+++GG 
Sbjct: 205 TGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGC 264

Query: 181 LLSC 184
           LL C
Sbjct: 265 LLCC 268


>gi|225703142 claudin 14 [Homo sapiens]
          Length = 239

 Score =  184 bits (468), Expect = 4e-47
 Identities = 91/207 (43%), Positives = 139/207 (67%), Gaps = 4/207 (1%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           MA++ +QLLGF ++ LG VG +  T +P W+ +++ G NI+TA +  KGLWM+CV  STG
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
           +  C++Y S+LAL   LQA RALMV+S +L  +A   A +GMKCTRC       K   A+
Sbjct: 61  IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPA-KTTFAI 119

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
            GG +FI+AGL  +VA SW  + +V +FYNPL+P+ +K+E G A+++G+  S+L ++GG 
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179

Query: 181 LLSCSCPGNESKAGYRVPRSYPKSNSS 207
           LL  SC   + +A YR  ++ P++ ++
Sbjct: 180 LLCLSC---QDEAPYRPYQAPPRATTT 203


>gi|21536294 claudin 14 [Homo sapiens]
          Length = 239

 Score =  184 bits (468), Expect = 4e-47
 Identities = 91/207 (43%), Positives = 139/207 (67%), Gaps = 4/207 (1%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           MA++ +QLLGF ++ LG VG +  T +P W+ +++ G NI+TA +  KGLWM+CV  STG
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
           +  C++Y S+LAL   LQA RALMV+S +L  +A   A +GMKCTRC       K   A+
Sbjct: 61  IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPA-KTTFAI 119

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
            GG +FI+AGL  +VA SW  + +V +FYNPL+P+ +K+E G A+++G+  S+L ++GG 
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179

Query: 181 LLSCSCPGNESKAGYRVPRSYPKSNSS 207
           LL  SC   + +A YR  ++ P++ ++
Sbjct: 180 LLCLSC---QDEAPYRPYQAPPRATTT 203


>gi|225703138 claudin 14 [Homo sapiens]
          Length = 239

 Score =  184 bits (468), Expect = 4e-47
 Identities = 91/207 (43%), Positives = 139/207 (67%), Gaps = 4/207 (1%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           MA++ +QLLGF ++ LG VG +  T +P W+ +++ G NI+TA +  KGLWM+CV  STG
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
           +  C++Y S+LAL   LQA RALMV+S +L  +A   A +GMKCTRC       K   A+
Sbjct: 61  IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPA-KTTFAI 119

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
            GG +FI+AGL  +VA SW  + +V +FYNPL+P+ +K+E G A+++G+  S+L ++GG 
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179

Query: 181 LLSCSCPGNESKAGYRVPRSYPKSNSS 207
           LL  SC   + +A YR  ++ P++ ++
Sbjct: 180 LLCLSC---QDEAPYRPYQAPPRATTT 203


>gi|6912314 claudin 14 [Homo sapiens]
          Length = 239

 Score =  184 bits (468), Expect = 4e-47
 Identities = 91/207 (43%), Positives = 139/207 (67%), Gaps = 4/207 (1%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           MA++ +QLLGF ++ LG VG +  T +P W+ +++ G NI+TA +  KGLWM+CV  STG
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
           +  C++Y S+LAL   LQA RALMV+S +L  +A   A +GMKCTRC       K   A+
Sbjct: 61  IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPA-KTTFAI 119

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
            GG +FI+AGL  +VA SW  + +V +FYNPL+P+ +K+E G A+++G+  S+L ++GG 
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179

Query: 181 LLSCSCPGNESKAGYRVPRSYPKSNSS 207
           LL  SC   + +A YR  ++ P++ ++
Sbjct: 180 LLCLSC---QDEAPYRPYQAPPRATTT 203


>gi|225703140 claudin 14 [Homo sapiens]
          Length = 239

 Score =  184 bits (468), Expect = 4e-47
 Identities = 91/207 (43%), Positives = 139/207 (67%), Gaps = 4/207 (1%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           MA++ +QLLGF ++ LG VG +  T +P W+ +++ G NI+TA +  KGLWM+CV  STG
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
           +  C++Y S+LAL   LQA RALMV+S +L  +A   A +GMKCTRC       K   A+
Sbjct: 61  IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPA-KTTFAI 119

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
            GG +FI+AGL  +VA SW  + +V +FYNPL+P+ +K+E G A+++G+  S+L ++GG 
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179

Query: 181 LLSCSCPGNESKAGYRVPRSYPKSNSS 207
           LL  SC   + +A YR  ++ P++ ++
Sbjct: 180 LLCLSC---QDEAPYRPYQAPPRATTT 203


>gi|40788011 claudin 8 [Homo sapiens]
          Length = 225

 Score =  184 bits (466), Expect = 6e-47
 Identities = 86/196 (43%), Positives = 126/196 (64%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           MA   L++ G  +  +G VG VA T +PQW++S++  +NI+  +  ++GLWM+CV Q+  
Sbjct: 1   MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
            M CK+YDS+LALS  LQA R LM  + V+ FLA  +A +GMKCTRC GD++  KA I +
Sbjct: 61  RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
             GIIFI+ G+  L+  SW  + I+ DFYN ++    K E G A+++GW  + ++I+GGA
Sbjct: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180

Query: 181 LLSCSCPGNESKAGYR 196
           L  C    NE  + YR
Sbjct: 181 LFCCVFCCNEKSSSYR 196


>gi|6912316 claudin 17 [Homo sapiens]
          Length = 224

 Score =  174 bits (441), Expect = 5e-44
 Identities = 82/198 (41%), Positives = 122/198 (61%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           MA   LQ+ G  +  LG VG +A T +PQW++S++ G NII  + +++GLWM+C+ Q+  
Sbjct: 1   MAFYPLQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARV 60

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
            + CK Y S+LAL  AL+  RALM V++ L  +A+ +   GMK  +C G ++  KA +  
Sbjct: 61  RLQCKFYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLG 120

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
             G++FI+ G+  L+  SW  + I+ DFYNP I    K E G A+F+GWA +A++ +GG 
Sbjct: 121 TSGVLFILTGIFVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIGGG 180

Query: 181 LLSCSCPGNESKAGYRVP 198
           LL   C  N  K GYR P
Sbjct: 181 LLCGFCCCNRKKQGYRYP 198


>gi|9966781 claudin 2 [Homo sapiens]
          Length = 230

 Score =  167 bits (423), Expect = 6e-42
 Identities = 76/195 (38%), Positives = 122/195 (62%), Gaps = 1/195 (0%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           MA+ GLQL+G+ + LLG +G +    +P W+ SSY G +I+TA    KGLWM+C T STG
Sbjct: 1   MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
           +  C +Y ++L L A +QA +A+MV S  +  LA  ++ +GM+CT    + + K  R+A+
Sbjct: 61  ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKD-RVAV 119

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
            GG+ FI+ GL   +  +W  H I+ DFY+PL+P ++K+E G A+++G   S   ++ G 
Sbjct: 120 AGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGI 179

Query: 181 LLSCSCPGNESKAGY 195
           +L  SC    +++ Y
Sbjct: 180 ILCFSCSSQRNRSNY 194


>gi|47716519 claudin 20 [Homo sapiens]
          Length = 219

 Score =  162 bits (409), Expect = 3e-40
 Identities = 83/209 (39%), Positives = 126/209 (60%), Gaps = 1/209 (0%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           MA++GLQLL F +AL G  G++  T +P W+++     NIITA     GLWMDC   STG
Sbjct: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
           M SC +  S+L+L   +QA RA MV++ VL  L +  +T+GMKCTR GG D+  K+  + 
Sbjct: 61  MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGG-DRETKSHASF 119

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
            GG+ F+ AG+++L++  WY  +I+ +F +  +P + K+E G AI+IG+  + L+ + G 
Sbjct: 120 AGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGM 179

Query: 181 LLSCSCPGNESKAGYRVPRSYPKSNSSKE 209
           +   SC     +A    P   P SN+  E
Sbjct: 180 IFCTSCIKRNPEARLDPPTQQPISNTQLE 208


>gi|5921465 claudin 10 isoform b [Homo sapiens]
          Length = 228

 Score =  158 bits (399), Expect = 4e-39
 Identities = 79/195 (40%), Positives = 119/195 (61%), Gaps = 3/195 (1%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           MA++  +++ F +++ GWV + +      W++S+  G  +IT    +  LW  CVT STG
Sbjct: 1   MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDG-TVITTATYWANLWKACVTDSTG 59

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
           + +CK + S+LAL   +QA R LM+ ++ LGF     A  GMKCT+ GG DK  KA+IA 
Sbjct: 60  VSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKA-KAKIAC 118

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
             GI+FI++GL ++  CS Y ++I T+F++PL     KYE G A+FIGWAG++L I+GG 
Sbjct: 119 LAGIVFILSGLCSMTGCSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIGGV 177

Query: 181 LLSCSCPGNESKAGY 195
           +   S   N     Y
Sbjct: 178 IFCFSISDNNKTPRY 192


>gi|7656981 claudin 15 [Homo sapiens]
          Length = 228

 Score =  154 bits (388), Expect = 7e-38
 Identities = 81/212 (38%), Positives = 125/212 (58%), Gaps = 10/212 (4%)

Query: 6   LQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSCK 65
           ++  GF MA +G + L        W++S+  G N+IT   +++ LW  C T S G+ +C 
Sbjct: 5   VETFGFFMATVGLLMLGVTLPNSYWRVSTVHG-NVITTNTIFENLWFSCATDSLGVYNCW 63

Query: 66  MYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGGII 125
            + S+LALS  +QA RALM+ +++LGFL + +   G++CT  GG +  +KA++A   G +
Sbjct: 64  EFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGAL 123

Query: 126 FIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGALL--S 183
            I+AG+  +VA SWY   I  DF++PL P   KYE GPA+++GW+ S + ILGG  L  +
Sbjct: 124 HILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGLCLCSA 182

Query: 184 CSCPGNESKAG-----YRVPRS-YPKSNSSKE 209
           C C  +E  A      Y+ P S  P + S +E
Sbjct: 183 CCCGSDEDPAASARRPYQAPVSVMPVATSDQE 214


>gi|33598916 claudin 10 isoform a [Homo sapiens]
          Length = 226

 Score =  145 bits (367), Expect = 2e-35
 Identities = 72/179 (40%), Positives = 111/179 (62%), Gaps = 3/179 (1%)

Query: 17  GWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSCKMYDSVLALSAA 76
           G+  LVA T   +W++++ A  ++ITA  +Y+GLWM+C   + G   C+ + ++  ++  
Sbjct: 15  GFGALVAATTSNEWKVTTRAS-SVITATWVYQGLWMNCAGNALGSFHCRPHFTIFKVAGY 73

Query: 77  LQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGGIIFIVAGLAALVA 136
           +QA R LM+ ++ LGF     A  GMKCT+ GG DK  KA+IA   GI+FI++GL ++  
Sbjct: 74  IQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKA-KAKIACLAGIVFILSGLCSMTG 132

Query: 137 CSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGALLSCSCPGNESKAGY 195
           CS Y ++I T+F++PL     KYE G A+FIGWAG++L I+GG +   S   N     Y
Sbjct: 133 CSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRY 190


>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
          Length = 261

 Score =  141 bits (356), Expect = 4e-34
 Identities = 77/221 (34%), Positives = 120/221 (54%), Gaps = 12/221 (5%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           MA +  Q LGF ++L+G  G++A T + QW       +N +TA   Y+GLW  CV +S+G
Sbjct: 1   MAVTACQGLGFVVSLIGIAGIIAATCMDQWSTQDLY-NNPVTAVFNYQGLWRSCVRESSG 59

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
              C+ Y ++L L A LQA RALM+V +VLG + + V+   +KC R G  +   KA + +
Sbjct: 60  FTECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFY----------NPLIPT-NIKYEFGPAIFIGW 169
             GI+FIV+GL A+   S + + +VT+F+            ++ T   +Y FG A+F+GW
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179

Query: 170 AGSALVILGGALLSCSCPGNESKAGYRVPRSYPKSNSSKEY 210
               L ++GG ++  +C G   +       SY  S  S  Y
Sbjct: 180 VAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAY 220


>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
          Length = 261

 Score =  140 bits (354), Expect = 6e-34
 Identities = 74/221 (33%), Positives = 118/221 (53%), Gaps = 12/221 (5%)

Query: 1   MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
           M+ +  Q++ F +++LG  G +A T +  W       DN +T+   Y+GLW  CV QS+G
Sbjct: 1   MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLY-DNPVTSVFQYEGLWRSCVRQSSG 59

Query: 61  MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
              C+ Y ++L L A LQA RALM+V +VLG + + V+   +KC R G  +   KA + +
Sbjct: 60  FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119

Query: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFY----------NPLIPT-NIKYEFGPAIFIGW 169
             GI+FIV+GL A+   S + + +VT+F+            ++ T   +Y FG A+F+GW
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179

Query: 170 AGSALVILGGALLSCSCPGNESKAGYRVPRSYPKSNSSKEY 210
               L ++GG ++  +C G   +       SY  S  S  Y
Sbjct: 180 VAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAY 220


>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score =  129 bits (323), Expect = 2e-30
 Identities = 66/183 (36%), Positives = 106/183 (57%), Gaps = 4/183 (2%)

Query: 4   SGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMS 63
           + +Q +G  ++LLGW+  +  T +P W+  +    ++   +    GLW  CV Q    M 
Sbjct: 7   TAMQSVGLLLSLLGWILSIITTYLPHWKNLNL---DLNEMENWTMGLWQTCVIQEEVGMQ 63

Query: 64  CKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGG 123
           CK +DS LAL A L+ +R LM +S  LGFL + V+  G+ C R G   +  K R+ + GG
Sbjct: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123

Query: 124 IIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNI-KYEFGPAIFIGWAGSALVILGGALL 182
           I+   +G+ ALV  SW  H+ V +F++  +P  + ++EFG A+F+GW     ++LGG LL
Sbjct: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183

Query: 183 SCS 185
           +C+
Sbjct: 184 NCA 186


>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
          Length = 207

 Score =  129 bits (323), Expect = 2e-30
 Identities = 70/179 (39%), Positives = 103/179 (57%), Gaps = 22/179 (12%)

Query: 17  GWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSCKMYDSVLALSAA 76
           G+  LVA T   +W++++ A  ++ITA  +Y+GLWM+C                   +  
Sbjct: 15  GFGALVAATTSNEWKVTTRAS-SVITATWVYQGLWMNC-------------------AGY 54

Query: 77  LQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGGIIFIVAGLAALVA 136
           +QA R LM+ ++ LGF     A  GMKCT+ GG DK  KA+IA   GI+FI++GL ++  
Sbjct: 55  IQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKA-KAKIACLAGIVFILSGLCSMTG 113

Query: 137 CSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGALLSCSCPGNESKAGY 195
           CS Y ++I T+F++PL     KYE G A+FIGWAG++L I+GG +   S   N     Y
Sbjct: 114 CSLYANKITTEFFDPLF-VEQKYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRY 171


>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score =  127 bits (319), Expect = 7e-30
 Identities = 65/183 (35%), Positives = 105/183 (57%), Gaps = 4/183 (2%)

Query: 4   SGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMS 63
           + +Q +G  ++ LGW+  +  T +P W+  +    ++   +    GLW  CV Q    M 
Sbjct: 7   TAMQSVGLLLSFLGWILSIITTYLPHWKNLNL---DLNEMENWTMGLWQTCVIQEEVGMQ 63

Query: 64  CKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGG 123
           CK +DS LAL A L+ +R LM +S  LGFL + V+  G+ C R G   +  K R+ + GG
Sbjct: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123

Query: 124 IIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNI-KYEFGPAIFIGWAGSALVILGGALL 182
           I+   +G+ ALV  SW  H+ V +F++  +P  + ++EFG A+F+GW     ++LGG LL
Sbjct: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183

Query: 183 SCS 185
           +C+
Sbjct: 184 NCA 186


>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score =  127 bits (319), Expect = 7e-30
 Identities = 65/183 (35%), Positives = 105/183 (57%), Gaps = 4/183 (2%)

Query: 4   SGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMS 63
           + +Q +G  ++ LGW+  +  T +P W+  +    ++   +    GLW  CV Q    M 
Sbjct: 7   TAMQSVGLLLSFLGWILSIITTYLPHWKNLNL---DLNEMENWTMGLWQTCVIQEEVGMQ 63

Query: 64  CKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGG 123
           CK +DS LAL A L+ +R LM +S  LGFL + V+  G+ C R G   +  K R+ + GG
Sbjct: 64  CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123

Query: 124 IIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNI-KYEFGPAIFIGWAGSALVILGGALL 182
           I+   +G+ ALV  SW  H+ V +F++  +P  + ++EFG A+F+GW     ++LGG LL
Sbjct: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183

Query: 183 SCS 185
           +C+
Sbjct: 184 NCA 186


>gi|162417973 claudin 22 [Homo sapiens]
          Length = 220

 Score =  127 bits (318), Expect = 9e-30
 Identities = 68/180 (37%), Positives = 102/180 (56%), Gaps = 4/180 (2%)

Query: 7   QLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSCKM 66
           QL G S++LLGWV       +P W+  +    ++   +    GLW  CV Q    M CK 
Sbjct: 10  QLAGVSLSLLGWVLSCLTNYLPHWKNLNL---DLNEMENWTMGLWQTCVIQEEVGMQCKD 66

Query: 67  YDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGGIIF 126
           +DS LAL A L+ +R LM +S  LGFL + V+  G+ C R G   +  K R+ + GGI+ 
Sbjct: 67  FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126

Query: 127 IVAGLAALVACSWYGHQIVTDFYNPLIPTNI-KYEFGPAIFIGWAGSALVILGGALLSCS 185
             +G+ ALV  SW  H+ V +F++  +P  + ++EFG A+F+GW     ++LGG LL C+
Sbjct: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186


>gi|157820127 claudin-like [Homo sapiens]
          Length = 229

 Score =  104 bits (260), Expect = 5e-23
 Identities = 69/202 (34%), Positives = 100/202 (49%), Gaps = 10/202 (4%)

Query: 6   LQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSCK 65
           +QL G  ++LLGWV     T +PQW+  +   + + T      G+W  CV +      CK
Sbjct: 9   VQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMET---WIMGIWEVCVDREEVATVCK 65

Query: 66  MYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGGII 125
            ++S L+L   LQ  R LMV S  LG L + + + G +C +      V K R+ + G  +
Sbjct: 66  AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125

Query: 126 FIVAGLAALVACSWYGHQIVTDFYNPLIPTNI-KYEFGPAIFIGWAGSALVILGGALLSC 184
              A    L+  SW  H  + DF++  IP  I ++EFG A+++GWA    + LGG LL  
Sbjct: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIF 185

Query: 185 S-CPGNES-----KAGYRVPRS 200
           S C G E       AG  VP S
Sbjct: 186 SACLGKEDVPFPLMAGPTVPLS 207


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.136    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,258,362
Number of Sequences: 37866
Number of extensions: 276065
Number of successful extensions: 868
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 784
Number of HSP's gapped (non-prelim): 45
length of query: 211
length of database: 18,247,518
effective HSP length: 98
effective length of query: 113
effective length of database: 14,536,650
effective search space: 1642641450
effective search space used: 1642641450
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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