Guide to the Human Genome
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Search of human proteins with 153791662

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153791662 coiled-coil domain containing 71 [Homo sapiens]
         (467 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153791662 coiled-coil domain containing 71 [Homo sapiens]          905   0.0  
gi|57242766 hypothetical protein LOC168455 [Homo sapiens]              65   1e-10
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        54   3e-07
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]            52   2e-06
gi|4885373 histone cluster 1, H1a [Homo sapiens]                       51   2e-06
gi|4885379 histone cluster 1, H1e [Homo sapiens]                       50   4e-06
gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]             49   7e-06
gi|239758151 PREDICTED: hypothetical protein XP_002346314 [Homo ...    48   2e-05
gi|4885381 histone cluster 1, H1b [Homo sapiens]                       48   2e-05
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]     47   5e-05
gi|24475863 H1 histone family, member O, oocyte-specific [Homo s...    46   6e-05
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         45   1e-04
gi|239751026 PREDICTED: hypothetical protein XP_002347678 [Homo ...    44   2e-04
gi|239748777 PREDICTED: hypothetical protein [Homo sapiens]            44   2e-04
gi|239745455 PREDICTED: hypothetical protein XP_002343496 [Homo ...    44   2e-04
gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens]             44   3e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     44   4e-04
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   43   5e-04
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   43   5e-04
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   43   5e-04
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    43   5e-04
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    43   7e-04
gi|50409691 SRp25 nuclear protein isoform 4 [Homo sapiens]             43   7e-04
gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens]             43   7e-04
gi|4885371 H1 histone family, member 0 [Homo sapiens]                  42   0.001
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    42   0.001
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    42   0.002
gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo ...    42   0.002
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           42   0.002
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           42   0.002

>gi|153791662 coiled-coil domain containing 71 [Homo sapiens]
          Length = 467

 Score =  905 bits (2339), Expect = 0.0
 Identities = 467/467 (100%), Positives = 467/467 (100%)

Query: 1   MSVVVQHVEEKAVHSWSRISTAGKKALEEALLVFNPMSQDLSATEAQLVAFLQGLRDDGF 60
           MSVVVQHVEEKAVHSWSRISTAGKKALEEALLVFNPMSQDLSATEAQLVAFLQGLRDDGF
Sbjct: 1   MSVVVQHVEEKAVHSWSRISTAGKKALEEALLVFNPMSQDLSATEAQLVAFLQGLRDDGF 60

Query: 61  QPTILRSGDVYGYSSCTANPPSQTKLQARAPNPTATSPPASAPRTAMRLPAGRATLLPMP 120
           QPTILRSGDVYGYSSCTANPPSQTKLQARAPNPTATSPPASAPRTAMRLPAGRATLLPMP
Sbjct: 61  QPTILRSGDVYGYSSCTANPPSQTKLQARAPNPTATSPPASAPRTAMRLPAGRATLLPMP 120

Query: 121 LSGRLAKASTPALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLE 180
           LSGRLAKASTPALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLE
Sbjct: 121 LSGRLAKASTPALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLE 180

Query: 181 ALVPLKTPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLT 240
           ALVPLKTPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLT
Sbjct: 181 ALVPLKTPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLT 240

Query: 241 RKGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVA 300
           RKGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVA
Sbjct: 241 RKGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVA 300

Query: 301 RTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQP 360
           RTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQP
Sbjct: 301 RTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQP 360

Query: 361 RGRGRPKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPKAWLGPGT 420
           RGRGRPKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPKAWLGPGT
Sbjct: 361 RGRGRPKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPKAWLGPGT 420

Query: 421 AKLLKFRAIKVDRRSSDDEVRQRAQRILRVNLSPVIRLQPLLPYSAV 467
           AKLLKFRAIKVDRRSSDDEVRQRAQRILRVNLSPVIRLQPLLPYSAV
Sbjct: 421 AKLLKFRAIKVDRRSSDDEVRQRAQRILRVNLSPVIRLQPLLPYSAV 467


>gi|57242766 hypothetical protein LOC168455 [Homo sapiens]
          Length = 235

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 48/128 (37%), Positives = 65/128 (50%), Gaps = 5/128 (3%)

Query: 9   EEKAVHSWSRISTAGK-KALEEALLVFNPMSQDLSATEAQLVAFLQGLRDDGFQPTILRS 67
           EEK V+S S++S A   KAL +A  +F P S +  +++A+L +FL  L+   F P ILRS
Sbjct: 37  EEKVVYSRSQLSLADSTKALGDAFKLFMPRSTEFMSSDAELWSFLCSLKHQ-FSPHILRS 95

Query: 68  GDVYGYSSCTA---NPPSQTKLQARAPNPTATSPPASAPRTAMRLPAGRATLLPMPLSGR 124
            DVYGYSSC A   +PP     + +A  P   +      R A    A R    P P    
Sbjct: 96  KDVYGYSSCRALVPDPPGPPTARGQARRPVPRAAARRRRRGARAAAARRRKPRPPPPPPP 155

Query: 125 LAKASTPA 132
             + S PA
Sbjct: 156 PPEESCPA 163



 Score = 36.6 bits (83), Expect = 0.050
 Identities = 34/116 (29%), Positives = 49/116 (42%), Gaps = 18/116 (15%)

Query: 360 PRGRG---RPKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPKAWL 416
           P  RG   RP   A AR  R+G   R     +++ R       PP++     P +P    
Sbjct: 115 PTARGQARRPVPRAAARRRRRGA--RAAAARRRKPRPPPPPPPPPEESCPAKPVAPGPCF 172

Query: 417 G---------PGTAKLLKFRAIKVDR----RSSDDEVRQRAQRILRVNLSPVIRLQ 459
           G           T  L  F  I+V        S    R+RA+++LRVNL P++RL+
Sbjct: 173 GGRTLEEIWRAATPTLTTFPTIRVGSDVWGERSLAAARRRARQVLRVNLEPMVRLR 228


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 82/402 (20%), Positives = 161/402 (40%), Gaps = 74/402 (18%)

Query: 82   SQTKLQARAPNPTATSPPASAP------RTAMRLPAGRATLLPMPLSGRLAKASTPALAK 135
            S +  + R P+P  +S   S+P      RTA R    R++  P   S    +  +   + 
Sbjct: 1638 SGSSSKGRGPSPEGSSSTESSPEHPPKSRTARR--GSRSSPEPKTKSRTPPRRRSSRSSP 1695

Query: 136  HATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPCLGAK 195
              T    LS   +S++S     +   P H                    + +P P    K
Sbjct: 1696 ELTRKARLSRRSRSASSSPETRSRTPPRH---------------RRSPSVSSPEPA--EK 1738

Query: 196  HKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPK---CLTRKGPGAGPRRGS 252
             ++   + S +    K     G+ P +P+P+  +++ S+  +     TR+   +G  + +
Sbjct: 1739 SRSSRRRRSASSPRTKTTSRRGRSP-SPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQST 1797

Query: 253  GHQSKTNRATGSPSVRRMKGGSALGTKT-AQAKVARTLAKAARAQAKVARTQAKAAKARA 311
              + + +R+  S   RR +GGS   +++ A+ + +RT ++  R +++   T  K +++R 
Sbjct: 1798 SRRRQRSRSR-SRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRT 1856

Query: 312  KAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAV---RAKAK---VARTQPRGRGR 365
                                     A W +++++A      R++++   ++R + R R  
Sbjct: 1857 SP-----------------------APWKRSRSRASPATHRRSRSRTPLISRRRSRSRTS 1893

Query: 366  PKGSAKART----TRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSP------KAW 415
            P    ++R+    TR+  ++R   V ++R R+      PP  R R   R+P      ++ 
Sbjct: 1894 PVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSR----TPPVTRRRSRSRTPTTRRRSRSR 1949

Query: 416  LGPGTAKLLKFRAIKVDRRSSDDEVRQRAQRILRVNLSPVIR 457
              P T +  + R   V RR S        +R  R   SPV R
Sbjct: 1950 TPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTR 1991



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 45/250 (18%), Positives = 108/250 (43%), Gaps = 21/250 (8%)

Query: 186 KTPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGP---GNPRPKAPRKTTSKGPKCLTRK 242
           +TP     ++ +  + + S + +P + R+S  + P   G  R + P +  S+    + R+
Sbjct: 576 RTPARRGRSRSRTPARRRSRSRTPTR-RRSRSRTPARRGRSRSRTPARRRSRTRSPVRRR 634

Query: 243 GPGAGPRRGSGHQ-----SKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQA 297
                P R SG       ++  R+      RR +  S    + +    +RT A+  R+++
Sbjct: 635 SRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRS 694

Query: 298 KV-----ARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAK 352
           +      +R+++   + R+ ++  Q + ++ + + +   K K   +  ++++ +     K
Sbjct: 695 RTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSER---KNKSRTSQRRSRSNSSPEMKK 751

Query: 353 AKVARTQPRGRGRPKGSAKARTTRK----GQKNRPETVGQKRKRAEEAKDLPPKKRTRLG 408
           ++++  + R    P+  AK+R + +    G    P+   Q   R   +    PK ++R  
Sbjct: 752 SRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTP 811

Query: 409 PRSPKAWLGP 418
           PR  ++   P
Sbjct: 812 PRRSRSSSSP 821



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 80/374 (21%), Positives = 149/374 (39%), Gaps = 66/374 (17%)

Query: 74  SSCTANPPSQTKLQAR----APNPTATSP--------PASAPRTAMRLPAGRATLLPMPL 121
           SS    PP+ T L A     +P P AT+P        P+ A  T  R P      LP   
Sbjct: 357 SSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSS 416

Query: 122 SGRLAKASTPA--LAKHATTNL--------------LLSSLKQSSASHARGAAVGFPTHL 165
           S   +  S     +++HA+++               + SS    + SH R       +H 
Sbjct: 417 SSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHT 476

Query: 166 YPGVYPAMRLSVVLEALVPLKTPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRP 225
                P+ R+          ++  P    + +++S       +P K   S  + P   R 
Sbjct: 477 -----PSRRMG---------RSRSPATAKRGRSRSR------TPTKRGHSRSRSPQWRRS 516

Query: 226 K-APRKTTSKGPKCLTRKGPGAGPRR-GSGHQSKTNRATGSPSVRRMKGGSALGTKTAQA 283
           + A R   S+ P+   R+G    P+R G      T R   S S RR +  S       ++
Sbjct: 517 RSAQRWGRSRSPQ---RRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRS 573

Query: 284 KVARTLAKAARAQAKV-ARTQAKA---AKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAW 339
           + +RT A+  R++++  AR ++++    + R++++    + +++++    +         
Sbjct: 574 R-SRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVR 632

Query: 340 AKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDL 399
            ++++++ A R+    +RT P  RGR +    AR  R   +      G+ R R       
Sbjct: 633 RRSRSRSPARRSGRSRSRT-PARRGRSRSRTPARRGRSRSRTPARRSGRSRSRT------ 685

Query: 400 PPKKRTRLGPRSPK 413
            P +R R   R+P+
Sbjct: 686 -PARRGRSRSRTPR 698



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 45/223 (20%), Positives = 97/223 (43%), Gaps = 35/223 (15%)

Query: 208 SPLKLRKSSGKGP---GNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSKTNRATGS 264
           SP    +S  + P   G  R + P +  S+      R+     P R    +S+T      
Sbjct: 566 SPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRT------ 619

Query: 265 PSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQVKAKAKA 324
           P+ RR +      T++   + +R+ + A R+    +RT A+  ++R++  A + +++++ 
Sbjct: 620 PARRRSR------TRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRT 673

Query: 325 KAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRP-----KGSAKARTT---- 375
            A +            +++++  A R +++ +RT  RGR R      +G + +RT     
Sbjct: 674 PARRS----------GRSRSRTPARRGRSR-SRTPRRGRSRSRSLVRRGRSHSRTPQRRG 722

Query: 376 RKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPKAWLGP 418
           R G  +  +   +  +R   +   P  K++R+  R  ++   P
Sbjct: 723 RSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSP 765



 Score = 38.1 bits (87), Expect = 0.017
 Identities = 65/346 (18%), Positives = 136/346 (39%), Gaps = 24/346 (6%)

Query: 81   PSQTKLQA-RAPNPTATSPPASAPRTAMRLPAGRATLLPMPL-----SGRLAKASTPALA 134
            PSQ+++ + RAP+P+  S    AP  ++  PA      P+P      S  L   +TP   
Sbjct: 2414 PSQSRMTSERAPSPS--SRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAG 2471

Query: 135  KHATTNLLLSSLKQSSASHARGAAVGFP--THLYPGVYPAMRLSVVLEALVPLKTPMPCL 192
              + ++  +++   S+  H    +V  P   H   G  PA   +    AL  L+   P  
Sbjct: 2472 SQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQ---PAK 2528

Query: 193  GAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPR-RG 251
              +  + S   S + S      SS    G+    +   +    P+   ++ P   P  + 
Sbjct: 2529 ERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKE 2588

Query: 252  SGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARA 311
            +  + +    T +   RR    S+  + ++ +  + + + ++ + +  + + + ++ + +
Sbjct: 2589 AVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-SSSSSSSSSSSS 2647

Query: 312  KAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVR-----AKAKVARTQPRGRGRP 366
                A+   +A  K A  K            +    ++R     + + V R +P  +  P
Sbjct: 2648 SPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSP 2707

Query: 367  K---GSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGP 409
            +    S+  R +R+GQ+    +   KR+R E     P + R+   P
Sbjct: 2708 RDQQSSSSERGSRRGQRGDSRSPSHKRRR-ETPSPRPMRHRSSRSP 2752



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 72/323 (22%), Positives = 121/323 (37%), Gaps = 55/323 (17%)

Query: 77   TANPP---SQTKLQAR-----APNPTATSPPASAPRTAMRLPAGRATLLPMPLSGRLAKA 128
            TA PP   S   L AR     AP P  +   A A   A R+PA  A  +       LA A
Sbjct: 2192 TARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAM------NLASA 2245

Query: 129  STPALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTP 188
             TPA+     T + L+  +  +A+ A   A        P    A     + +   P    
Sbjct: 2246 RTPAI----PTAVNLADSRTPAAAAAMNLA-------SPRTAVAPSAVNLADPRTPTAPA 2294

Query: 189  MPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPR-PKAPRKTTSKGPKCLTRKGPGAG 247
            +   GA+  A    LSL  S      ++   P + R P+AP      GP    R      
Sbjct: 2295 VNLAGARTPAALAALSLTGSGTP--PTAANYPSSSRTPQAPASANLVGP----RSAHATA 2348

Query: 248  PRRGSGHQSKTNRATGSPSVRRM----KGGSALGTKTAQAKVARTLAKAA-----RAQAK 298
            P   +G ++    A  S +  RM     G +    +   +   R   + +     RA+++
Sbjct: 2349 PVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSR 2408

Query: 299  V---ARTQAKAAKARA---KAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAK 352
                A +Q++    RA    ++  Q  +++    AQ + ++ V +A++         +++
Sbjct: 2409 TPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSD--------QSR 2460

Query: 353  AKVARTQPRGRGRPKGSAKARTT 375
              +A+T P    +   S    TT
Sbjct: 2461 CLIAQTTPVAGSQSLSSGAVATT 2483



 Score = 29.6 bits (65), Expect = 6.1
 Identities = 24/93 (25%), Positives = 39/93 (41%), Gaps = 6/93 (6%)

Query: 357 RTQPRGRGRPKGSAKARTTRKG----QKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSP 412
           + + + RGR   S+  R  RK     +K+R E+  +KRK          K + +   RS 
Sbjct: 190 KKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSR 249

Query: 413 KAWLGPGTAKLLKFRAIKVDRRSSDDEVRQRAQ 445
                P + +    R+   D  SS D  R R++
Sbjct: 250 STTPAPKSRRA--HRSTSADSASSSDTSRSRSR 280


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 80/344 (23%), Positives = 120/344 (34%), Gaps = 37/344 (10%)

Query: 85  KLQARAPNPTATSPPASAPRTAMRLPA--GRATLLPMPLSGRLAK----ASTPALAKHAT 138
           KL+ +  N            TA   PA  GR    P  L G+  +       P       
Sbjct: 273 KLRRQGQNAALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKA 332

Query: 139 TNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPCLGAKHKA 198
           T    +  K+      + A VG  +          R         P +      GAK + 
Sbjct: 333 TKAAAAGTKRGGGGQQKAAVVGVKS----------RKKQRRRGKKPRRQKASAAGAKSRG 382

Query: 199 QSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSKT 258
              +  L ++     K  G G   PR + PR+   K P    R G    PRR     +K+
Sbjct: 383 GGDKKGLREA-----KRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKS 437

Query: 259 ----NRATGSPSVRRMKGGSALGTKTAQAKV-ARTLAKAARAQAKVARTQAKAAKARAKA 313
               +R+ G    RR   G     K A+A   +R   K  R +A  A T+++    ++ +
Sbjct: 438 RGGKSRSGGGKKPRRR--GQKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLKSHS 495

Query: 314 KAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPR-----GRGRPKG 368
                +   KA+AA  KA     AA AK++ + +  R K  VA  + R      R R K 
Sbjct: 496 GKNLWRRGQKAEAAGEKA----TAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKA 551

Query: 369 SAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSP 412
            A   T+  G  N+    G   K  +  +     K    G + P
Sbjct: 552 VAAGATSHGGGGNKQSRGGGGNKPRQWGQTAAAAKTRGGGDKQP 595



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 57/238 (23%), Positives = 90/238 (37%), Gaps = 25/238 (10%)

Query: 226 KAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAK- 284
           K P+K   +G K  T      G  RG G +    +   +      + G+A   +   AK 
Sbjct: 243 KKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGEKPAAKG 302

Query: 285 --------VARTLAKAARAQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVM 336
                   +     +  R   K  R   KA KA A         + KA    VK++ K  
Sbjct: 303 RGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKK-- 360

Query: 337 AAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRKGQKNRPETVGQKRKRAEEA 396
               + +   K  R KA  A  + RG G  KG  +A+  R+G   +       R+RA++A
Sbjct: 361 ----QRRRGKKPRRQKASAAGAKSRGGGDKKGLREAK--RRGDGRKKPRWQNPRRRAQKA 414

Query: 397 KDLPP-----KKRTRLGPRSPKAWLG---PGTAKLLKFRAIKVDRRSSDDEVRQRAQR 446
               P     KK  R GP++ K+  G    G  K  + R  K  +++++     R  +
Sbjct: 415 PAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGAESRGDK 472



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 43/167 (25%), Positives = 76/167 (45%), Gaps = 18/167 (10%)

Query: 243 GPGAGPRRGSGHQSKTNRAT------GSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQ 296
           G G    RG G Q      T      G    RR +  +A G+K  + +  +  + AA ++
Sbjct: 94  GAGGAENRGGGEQKAAAAGTKSLGGRGRKPRRRGQKAAATGSKKPRWRAQK--SAAAGSK 151

Query: 297 AKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKA----KAKAVRAK 352
            + A  Q  AA A  K++  +   KA A  A+ ++  K     AK++     K +   AK
Sbjct: 152 NRGAGAQKAAAAAGVKSQGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAK 211

Query: 353 AKVARTQPRGR---GRPKGSAKARTTRKGQKNRPETVGQKRKRAEEA 396
           ++  +T+   R    RPK +A    +R+G   +P+   ++R+R ++A
Sbjct: 212 SRFGKTRGGRRKKHRRPKPAAGGAKSRRGGGKKPQ---KQRRRGQKA 255



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 58/230 (25%), Positives = 87/230 (37%), Gaps = 31/230 (13%)

Query: 201 LQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRG--------- 251
           L  +LA +P++L   S   P      A  K    G K L R+   AG ++          
Sbjct: 22  LGAALARTPVELAAESA-APALSAAAAGVKILGSGDKKLRRQKAAAGGKKARLRGQKGAV 80

Query: 252 SGHQSKTN--RATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKA 309
           +G +++ +  +A G+       GG           +     K  R   K A T +K  + 
Sbjct: 81  AGKEARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRGRKPRRRGQKAAATGSKKPRW 140

Query: 310 RAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGS 369
           RA+  AA       A A +  A A V +   +   KA A  AK++  + +PR        
Sbjct: 141 RAQKSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAAAAGAKSRSGK-KPR-------- 191

Query: 370 AKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKR--TRLGPRSPKAWLG 417
                 R+G K+R +    K+ R  EAK    K R   R   R PK   G
Sbjct: 192 ------RRGAKSRGDE--DKKGRQREAKSRFGKTRGGRRKKHRRPKPAAG 233



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 26/104 (25%), Positives = 41/104 (39%), Gaps = 7/104 (6%)

Query: 217 GKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRG-------SGHQSKTNRATGSPSVRR 269
           G  P   R K PR   S+G      +G G    RG       SG ++  +++ G    +R
Sbjct: 707 GINPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKSRSGKKAAASKSHGGGGAKR 766

Query: 270 MKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKA 313
            +GG A      +A  A     AA    K  R +++  + +  A
Sbjct: 767 RRGGGAKSRSGEKAVTAGGQKAAAAGGKKPPRVKSRGGRGQKAA 810



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 55/234 (23%), Positives = 89/234 (38%), Gaps = 34/234 (14%)

Query: 211 KLRKSSGKGPGNPRPKA---PRKTTSKGPKCLTRKGPGAGP-------RRGSGHQSKTNR 260
           K R    K PG  +  A     ++   G K   +K  G G        RRG    +   +
Sbjct: 586 KTRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGAKSRKKPWRRGQKDAAAAEK 645

Query: 261 ATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQVKA 320
           A  + +  R  GG     +   A  + + A AA  Q   AR + +  +A+++    Q  A
Sbjct: 646 AWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQEAEARKKPRRRRAKSRGDGGQNAA 705

Query: 321 ------KAKAKAAQVKAKAKVMAAWAKAKAKAKA-------VRAKAKVARTQPRGRGRPK 367
                 + + K  ++        A ++    AK+        R+  K A ++  G G  K
Sbjct: 706 VGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKSRSGKKAAASKSHGGGGAK 765

Query: 368 ----GSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPKAWLG 417
               G AK+R+  K       T G ++  A   K  PP+ ++R G R  KA  G
Sbjct: 766 RRRGGGAKSRSGEKA-----VTAGGQKAAAAGGKK-PPRVKSR-GGRGQKAAAG 812


>gi|4885373 histone cluster 1, H1a [Homo sapiens]
          Length = 215

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 47/136 (34%), Positives = 61/136 (44%), Gaps = 10/136 (7%)

Query: 235 GPKCLTRKGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAAR 294
           G K L  KG      +G+G          + SV    G S + TKT     ++ L KA  
Sbjct: 86  GIKSLVSKGTLV-QTKGTGASGSFKLNKKASSVETKPGASKVATKTKATGASKKLKKATG 144

Query: 295 AQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAK 354
           A  K  +T  KA K  A  K+++   K K     VK K KV    AK+ AKAKAV+ KA 
Sbjct: 145 ASKKSVKTPKKAKKPAATRKSSKNPKKPKT----VKPK-KV----AKSPAKAKAVKPKAA 195

Query: 355 VARTQPRGRGRPKGSA 370
            AR       +PK +A
Sbjct: 196 KARVTKPKTAKPKKAA 211



 Score = 36.2 bits (82), Expect = 0.065
 Identities = 50/204 (24%), Positives = 78/204 (38%), Gaps = 23/204 (11%)

Query: 207 DSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSKTNRATGSPS 266
           + PL  +K+  K P      + +K        L  +   +   RG    +   +A  +  
Sbjct: 16  EKPLAGKKA--KKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALKKALAAAG 73

Query: 267 VRRMKGGSA--LGTKTAQAKVARTLAKAARA--------QAKVARTQAKAAKARAKAKAA 316
               K  S   LG K+  +K      K   A        +A    T+  A+K   K KA 
Sbjct: 74  YDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPGASKVATKTKAT 133

Query: 317 QVKAK------AKAKAAQVKAKAKVMAAWAKAK---AKAKAVRAKAKVARTQPRGRGRPK 367
               K      A  K+ +   KAK  AA  K+     K K V+ K KVA++  + +    
Sbjct: 134 GASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPK-KVAKSPAKAKAVKP 192

Query: 368 GSAKARTTRKGQKNRPETVGQKRK 391
            +AKAR T K +  +P+    K+K
Sbjct: 193 KAAKARVT-KPKTAKPKKAAPKKK 215


>gi|4885379 histone cluster 1, H1e [Homo sapiens]
          Length = 219

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 56/215 (26%), Positives = 77/215 (35%), Gaps = 16/215 (7%)

Query: 216 SGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSA 275
           S   P  P   AP + T    K   RK  GA  R+ SG            + +   G S 
Sbjct: 2   SETAPAAPAAPAPAEKTPVKKKA--RKSAGAAKRKASGPPVSELITKAVAASKERSGVSL 59

Query: 276 LGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKV 335
              K A A        AA    +   ++ K       +K   V+ K    +   K   K 
Sbjct: 60  AALKKALA--------AAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKA 111

Query: 336 MAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRKGQKNRPETVGQKRKRAEE 395
               A  +AK KA +A A  A+       +PK +  A T +K  K  P+   +    A  
Sbjct: 112 ----ASGEAKPKAKKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGA 167

Query: 396 AKDLPPKKRTRLGPRSPKAWLGPGTAKLLKFRAIK 430
            K   PKK     P+  KA   P  AK +K +A K
Sbjct: 168 KKAKSPKKAKAAKPK--KAPKSPAKAKAVKPKAAK 200



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 45/124 (36%), Positives = 54/124 (43%), Gaps = 4/124 (3%)

Query: 271 KGGSALGTKTAQAKVARTLAK--AARAQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQ 328
           KG  A G+     K A   AK  A +A A  A+  A AAK   KA  A    K+ AK   
Sbjct: 97  KGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAGAAKKPKKATGAATPKKS-AKKTP 155

Query: 329 VKAKAKVMAAWAK-AKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRKGQKNRPETVG 387
            KAK    AA AK AK+  KA  AK K A   P      K  A    T K +  +P+   
Sbjct: 156 KKAKKPAAAAGAKKAKSPKKAKAAKPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAA 215

Query: 388 QKRK 391
            K+K
Sbjct: 216 AKKK 219



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 38/109 (34%), Positives = 53/109 (48%), Gaps = 7/109 (6%)

Query: 291 KAARAQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAK---AKAKAK 347
           KAA  +AK    +A AAKA+  A AA+ K K    AA  K  AK     AK   A A AK
Sbjct: 110 KAASGEAKPKAKKAGAAKAKKPAGAAK-KPKKATGAATPKKSAKKTPKKAKKPAAAAGAK 168

Query: 348 AVRAKAKVARTQPRGRGRPKGSAKARTTRKGQKNRPETVGQKRKRAEEA 396
             ++  K    +P  +  PK  AKA+   K +  +P+T   K  + ++A
Sbjct: 169 KAKSPKKAKAAKP--KKAPKSPAKAKAV-KPKAAKPKTAKPKAAKPKKA 214



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 44/150 (29%), Positives = 60/150 (40%), Gaps = 18/150 (12%)

Query: 229 RKTTSKGPKCLTRKGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTA-QAKVAR 287
           +   SKG    T KG GA    GS   +K   A+G    +  K G+A   K A  AK  +
Sbjct: 85  KSLVSKGTLVQT-KGTGAS---GSFKLNK-KAASGEAKPKAKKAGAAKAKKPAGAAKKPK 139

Query: 288 TLAKAARAQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAK 347
               AA  +    +T  KA K  A A A + K+  KAKAA+ K            KA   
Sbjct: 140 KATGAATPKKSAKKTPKKAKKPAAAAGAKKAKSPKKAKAAKPK------------KAPKS 187

Query: 348 AVRAKAKVARTQPRGRGRPKGSAKARTTRK 377
             +AKA   +       +PK +   +   K
Sbjct: 188 PAKAKAVKPKAAKPKTAKPKAAKPKKAAAK 217



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 54/227 (23%), Positives = 87/227 (38%), Gaps = 40/227 (17%)

Query: 93  PTATSPPASAPRTAMRLPAGRATLLPMPLSGRLAKASTPALAKHATTNLLLSSLKQSSAS 152
           P A + PA A +T ++  A ++            KAS P +++   T  + +S ++S  S
Sbjct: 6   PAAPAAPAPAEKTPVKKKARKSA------GAAKRKASGPPVSE-LITKAVAASKERSGVS 58

Query: 153 HARG----AAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPCLG--------------- 193
            A      AA G+            R+ + L++LV   T +   G               
Sbjct: 59  LAALKKALAAAGYDVEKNNS-----RIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAAS 113

Query: 194 --AKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRG 251
             AK KA+    + A  P    K   K  G   PK   K+  K PK   +    AG ++ 
Sbjct: 114 GEAKPKAKKAGAAKAKKPAGAAKKPKKATGAATPK---KSAKKTPKKAKKPAAAAGAKKA 170

Query: 252 SGHQ----SKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAAR 294
              +    +K  +A  SP+  +     A   KTA+ K A+    AA+
Sbjct: 171 KSPKKAKAAKPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAK 217


>gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]
          Length = 352

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 45/247 (18%), Positives = 94/247 (38%), Gaps = 1/247 (0%)

Query: 200 SLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAG-PRRGSGHQSKT 258
           +L++  A +   +R    +GP      A       G   +  KG GA  P R +   +  
Sbjct: 36  ALEVGAASADTGVRGCGARGPAPLLASAGGGRARDGTWGVRTKGSGAALPSRPASRAAPR 95

Query: 259 NRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQV 318
             A+  P       G   G +  +A+ A     + +     +R++ + ++ R K      
Sbjct: 96  PEASSPPLPLEKARGGLSGPQGGRARGAMAHVGSRKRSRSRSRSRGRGSEKRKKKSRKDT 155

Query: 319 KAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRKG 378
                A  +Q +  +    A  ++K KA+     +  + +          S+ + ++  G
Sbjct: 156 SRNCSASTSQGRKASTAPGAEERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDG 215

Query: 379 QKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPKAWLGPGTAKLLKFRAIKVDRRSSDD 438
           +K R +   ++RK+ ++ K L  K + +   +  +A  GP   +  +    + D     D
Sbjct: 216 RKKRGKYKDKRRKKKKKRKKLKKKGKEKAEAQQVEALPGPSLDQWHRSAGEEEDGPVLTD 275

Query: 439 EVRQRAQ 445
           E + R Q
Sbjct: 276 EQKSRIQ 282


>gi|239758151 PREDICTED: hypothetical protein XP_002346314 [Homo
           sapiens]
          Length = 321

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 56/227 (24%), Positives = 91/227 (40%), Gaps = 22/227 (9%)

Query: 196 HKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPK-CLTRKGPGAGPRRGSGH 254
           H+ Q  + S+  +  +  +S G+G     P     +T  GP+ CL++    +G R     
Sbjct: 83  HRGQVQRRSMQAAAAQ-EQSLGRGCLGKEPPKWESSTRSGPRRCLSQDASRSGSRVCRSR 141

Query: 255 QSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAK 314
                R  G    RR +  +  G K+    V       +R   K+ R   KAA A AK+ 
Sbjct: 142 PQ--TRGGGGKKPRRGQKAATAGAKSRGGGVR------SRGGKKIRRRGQKAAAAGAKSC 193

Query: 315 AAQVKAKAKAKAA--------QVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRP 366
               K   KA+A         +++ + K  AA    KA  K +R + +  R +PR RG+ 
Sbjct: 194 GGGGKKPQKARAVGARRRGWKKLRRRGKKAAAAGGEKA-GKKLRQQGEKGRKKPRRRGQK 252

Query: 367 KGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPK 413
             +A     +K ++ +   V  K  +    + L      RLG  S K
Sbjct: 253 AAAAGGERCKKPRRQKAAAVSAKSPKKPRRRVL---NSARLGAESRK 296


>gi|4885381 histone cluster 1, H1b [Homo sapiens]
          Length = 226

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 51/152 (33%), Positives = 67/152 (44%), Gaps = 13/152 (8%)

Query: 229 RKTTSKGPKCLTRKGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVART 288
           +   SKG    T KG GA    GS   +K   A+G    +  K G+A   K A A   + 
Sbjct: 88  KSLVSKGTLVQT-KGTGAS---GSFKLNK-KAASGEAKPKAKKAGAAKAKKPAGA-TPKK 141

Query: 289 LAKAARAQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKA 348
             KAA A+  V +T  KA K  A       K+  KAKAA    KA       K+ AK KA
Sbjct: 142 AKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKA------TKSPAKPKA 195

Query: 349 VRAKAKVARTQPRGRGRPKGSAKARTTRKGQK 380
           V+ KA   +       +PK +AKA+     +K
Sbjct: 196 VKPKAAKPKAAKPKAAKPK-AAKAKKAAAKKK 226



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 57/206 (27%), Positives = 77/206 (37%), Gaps = 13/206 (6%)

Query: 208 SPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRG--SGHQSKTNRATGSP 265
           SP K +K++ K  G    K  RK T      L  K   A   R   S    K   A G  
Sbjct: 18  SPAK-KKATKKAAGAGAAK--RKATGPPVSELITKAVAASKERNGLSLAALKKALAAGGY 74

Query: 266 SVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQV-KAKAKA 324
            V +      LG K+  +K      K   A     +   KAA   AK KA +   AKAK 
Sbjct: 75  DVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSF-KLNKKAASGEAKPKAKKAGAAKAKK 133

Query: 325 KAAQVKAKAKVMAAWAKA------KAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRKG 378
            A     KAK  A   KA      KAK  A     KVA++  + +   K     ++  K 
Sbjct: 134 PAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKP 193

Query: 379 QKNRPETVGQKRKRAEEAKDLPPKKR 404
           +  +P+    K  + + AK    K +
Sbjct: 194 KAVKPKAAKPKAAKPKAAKPKAAKAK 219



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 42/143 (29%), Positives = 61/143 (42%), Gaps = 12/143 (8%)

Query: 250 RGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKA 309
           +G+  Q+K   A+GS  + +          + +AK     A AA+A+     T  KA KA
Sbjct: 93  KGTLVQTKGTGASGSFKLNKKAA-------SGEAKPKAKKAGAAKAKKPAGATPKKAKKA 145

Query: 310 RAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKA---KAVRAKAKVARTQPRGRGRP 366
            A AK A  K   KAK        KV  +  KAKA A   KA ++ AK    +P+   +P
Sbjct: 146 -AGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKPKA-AKP 203

Query: 367 KGSAKARTTRKGQKNRPETVGQK 389
           K +       K  K +     +K
Sbjct: 204 KAAKPKAAKPKAAKAKKAAAKKK 226


>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
          Length = 951

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 82/391 (20%), Positives = 142/391 (36%), Gaps = 34/391 (8%)

Query: 10  EKAVHSWSRISTAGKKALEEALLV---------FNPMSQDLSATEAQLVAFLQG---LRD 57
           E A    +R  + GKK    +  V         F P+S  + A E  L+   +    L D
Sbjct: 543 EDAAEVGARAGSGGKKEASSSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDD 602

Query: 58  DGFQPTILRSGDVYGYSSCTANPPSQTKLQARAPNPTATSPPASAPRTAMRLPAGRATLL 117
           D       + G     S+   NP       A AP P           T   L A +A   
Sbjct: 603 DSDDDEESKEGQESSSSAANTNP-------AVAP-PCVVVEEKKPQLTQEELEAKQAK-- 652

Query: 118 PMPLSGRLAKASTPALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSV 177
              L  RLA A+   LA+ +      S  KQ  A   R AA+   T   P   P      
Sbjct: 653 -QKLEDRLAAAAREKLAQASKE----SKEKQLQAERKRKAALFLQTLKNP--LPEAEAGK 705

Query: 178 VLEALVPLK----TPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTS 233
           + E+   ++    TP P L       +L++   D P    K   +     + K   K  S
Sbjct: 706 IEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRS 765

Query: 234 KGPKCLTRKGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAA 293
           +      +    +  R  S  ++K +  +   +VRR +  S    + A +   R   ++ 
Sbjct: 766 RTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSV 825

Query: 294 RAQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKA 353
               +V+R+   A++ R ++++   K K +   ++ K+KA+  +     +A  +     A
Sbjct: 826 PTAYRVSRSPG-ASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAA 884

Query: 354 KVARTQPRGRGRPKGSAKARTTRKGQKNRPE 384
             A +        +GS++ R+    Q+   +
Sbjct: 885 HSAHSASVSPVESRGSSQERSRGVSQEKEAQ 915



 Score = 33.5 bits (75), Expect = 0.42
 Identities = 47/175 (26%), Positives = 66/175 (37%), Gaps = 25/175 (14%)

Query: 249 RRGSGHQSKTNRATGSPSV-----RRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQ 303
           +  S   + TN A   P V     +       L  K A+ K+   LA AAR         
Sbjct: 614 QESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAARE-------- 665

Query: 304 AKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQP--- 360
            K A+A  ++K  Q++A+ K KAA      K     A+A  K +      + + T P   
Sbjct: 666 -KLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEA-GKIEESPFSVEESSTTPCPL 723

Query: 361 --RGRGRPKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPK 413
              GR  P    K       +   P      R+  +E K    KKR+R   RSPK
Sbjct: 724 LTGGRPLPTLEVKPPDRPSSKSKDPP-----REEEKEKKKKKHKKRSRTRSRSPK 773


>gi|24475863 H1 histone family, member O, oocyte-specific [Homo
           sapiens]
          Length = 346

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 62/239 (25%), Positives = 98/239 (41%), Gaps = 31/239 (12%)

Query: 195 KHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGH 254
           K K Q  +++ A +P +  ++ GKGP     K P +     P     K     P +    
Sbjct: 132 KKKIQPRKMAPATAPRRAGEAKGKGP-----KKPSEAKEDPPNVGKVKKAAKRPAKVQKP 186

Query: 255 QSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAK 314
             K   AT      R +GG+A  T+ AQ+  AR          KV     KA +A + A 
Sbjct: 187 PPKPGAATEKA---RKQGGAAKDTR-AQSGEAR----------KVPPKPDKAMRAPSSAG 232

Query: 315 AAQVKAKAK-AKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKAR 373
               KAKAK ++++Q  A+A     + K KA++K+ +  A   +       + K  AKA+
Sbjct: 233 GLSRKAKAKGSRSSQGDAEA-----YRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAK 287

Query: 374 TTRKGQKNRPETVGQKRKRAEEAKDLPP----KKRTRLGPRSPKAWLGPGTAKLLKFRA 428
             + GQ   P T      +   +K +P     K     GPR     +   ++K+   RA
Sbjct: 288 APKAGQ--GPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSSQRA 344


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 71/324 (21%), Positives = 120/324 (37%), Gaps = 72/324 (22%)

Query: 77  TANPPSQTKLQARAPNPTATSPPASAPRTAMRLPAGRATLLPMPLSGRLAKASTPALAKH 136
           T +PP +     R+P+P   SPP    R +   P  R T  P P   R A  S P     
Sbjct: 581 TPSPPPRR----RSPSPRRYSPPIQR-RYSPSPPPKRRTASPPPPPKRRASPSPP----- 630

Query: 137 ATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPCLGAKH 196
                      +   SH+                P  R S V       K   P L +KH
Sbjct: 631 ----------PKRRVSHSPP--------------PKQRSSPV------TKRRSPSLSSKH 660

Query: 197 K---AQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSG 253
           +   + S     A SP   ++ S     +PRP+AP+ ++S  P    R+G  + P+R   
Sbjct: 661 RKGSSPSRSTREARSPQPNKRHS----PSPRPRAPQTSSSPPP---VRRGASSSPQR--- 710

Query: 254 HQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKA 313
                 R + SPS R ++       + ++    + + KAA    +  R  + +       
Sbjct: 711 ------RQSPSPSTRPIR-------RVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSP 757

Query: 314 KAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKAR 373
           + A  K  A     Q ++ +     W+ A       +AK+      P      +G  K +
Sbjct: 758 EPAAKKPPAPPSPVQSQSPS---TNWSPA---VPVKKAKSPTPSPSPPRNSDQEGGGKKK 811

Query: 374 TTRKGQKNRPETVGQKRKRAEEAK 397
             +K +K++ +   +K K+ ++ K
Sbjct: 812 KKKKDKKHKKDKKHKKHKKHKKEK 835



 Score = 37.0 bits (84), Expect = 0.038
 Identities = 37/190 (19%), Positives = 74/190 (38%), Gaps = 14/190 (7%)

Query: 224 RPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSKTNRATG-SPSVRRMKGGSALGTKTAQ 282
           R ++PR+  S+ P    R  P    R+ S  +S  +R    SPS    K           
Sbjct: 168 RSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPS 227

Query: 283 AKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKA 342
            KV     + A + + + +          K  + +  +K + +  + + +++       +
Sbjct: 228 VKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSR-------S 280

Query: 343 KAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPK 402
           ++K+++       + T+PR R R +  + +   R   + RP      R+R    +  PP 
Sbjct: 281 RSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRP----SPRRRTPPRRMPPPP 336

Query: 403 KRTRLGPRSP 412
           +  R   RSP
Sbjct: 337 RHRR--SRSP 344



 Score = 37.0 bits (84), Expect = 0.038
 Identities = 68/370 (18%), Positives = 123/370 (33%), Gaps = 71/370 (19%)

Query: 80  PPSQTKLQARAPNPTATSPPASAPRTAMRLPAGRATLLPMPLSGRLAKASTPALAKHATT 139
           P  + + ++R+ +P     P   P    R P  R     MP   R  ++ +P   +  ++
Sbjct: 298 PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRR-----MPPPPRHRRSRSPVRRRRRSS 352

Query: 140 NLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPCLGAKHKAQ 199
             L  S   SS+S +R                            P K P        K +
Sbjct: 353 ASLSGSSSSSSSSRSRSP--------------------------PKKPPKRTSSPPRKTR 386

Query: 200 SLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSG----HQ 255
             +LS + SP + R+     P  P PK     T +      +      P R SG    H+
Sbjct: 387 --RLSPSASPPR-RRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHK 443

Query: 256 SKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKA 315
               R + SP+ +  K   +   +    K+A   +   R Q +    Q+ +    + +  
Sbjct: 444 GTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSE 503

Query: 316 AQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTT 375
            +   ++  K  +V  + +       + +++ +   + +   T PRGR R   S      
Sbjct: 504 DERPKRSHVKNGEVGRRRR------HSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRR 557

Query: 376 RKG-------QKNRPETVGQKRK--------------------RAEEAKDLPPKKRTRLG 408
           R+        ++ R  T   +R+                    +   +   PPK+RT   
Sbjct: 558 RRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASP 617

Query: 409 PRSPKAWLGP 418
           P  PK    P
Sbjct: 618 PPPPKRRASP 627



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 52/258 (20%), Positives = 88/258 (34%), Gaps = 26/258 (10%)

Query: 81  PSQTKLQARAPNPT---ATSPPASAPRTAMRLPAGRATLLPMPLSGRLAKASTPALAKHA 137
           PS++  +AR+P P    + SP   AP+T+   P  R      P   +    ST  + + +
Sbjct: 666 PSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVS 725

Query: 138 TTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPCLGAKHK 197
            T       K +S S      V     +     PA +           K P P    + +
Sbjct: 726 RTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAK-----------KPPAPPSPVQSQ 774

Query: 198 AQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSK 257
           + S   S A  P+K  KS       P P  PR +  +G       G     ++   H+  
Sbjct: 775 SPSTNWSPA-VPVKKAKSP-----TPSPSPPRNSDQEG------GGKKKKKKKDKKHKKD 822

Query: 258 TNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQ 317
                     +     +A       A +A      A+ +   A    K  ++ A+     
Sbjct: 823 KKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEAEDNLDD 882

Query: 318 VKAKAKAKAAQVKAKAKV 335
           ++   + KA +   KA+V
Sbjct: 883 LEKHLREKALRSMRKAQV 900


>gi|239751026 PREDICTED: hypothetical protein XP_002347678 [Homo
           sapiens]
          Length = 304

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 56/202 (27%), Positives = 81/202 (40%), Gaps = 17/202 (8%)

Query: 213 RKSSGKGPGNPRPKAP-RKTTSKGPKCLTRKGPGAGPRRGSGHQSKTNRATGSPSVRRMK 271
           R   G GPG   P+A  R     G +C TR G G  P  GSG +   +R   SPS  R  
Sbjct: 77  RSPRGAGPGAAGPRAAGRGGAGGGGRCCTR-GRGRFPCAGSGGRGARSRGCHSPSCCR-- 133

Query: 272 GGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAA-QVKAKAKAKAAQVK 330
                 +  A  +  +   + A  +A  A     A + R    AA  + A+A A  A  +
Sbjct: 134 -----SSSCAWHRWPQLRGREAEPRASPALLICIAPRPRPALPAALHIGARATAGLAAKR 188

Query: 331 AKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRKGQKNRPETVGQKR 390
           A+ ++ +A   A+ +    R +A    T P  R RP G       R G +    T  +  
Sbjct: 189 AQPQLCSAGTAARGR----RTRAS-PPTPP--RPRPPGLRSGDVPRGGARVERPTGRRGA 241

Query: 391 KRAEEAKDLPPKKRTRLGPRSP 412
                A+ +PP+   RL P  P
Sbjct: 242 GGRGGAQRIPPRPLRRLVPIHP 263


>gi|239748777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 350

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 69/254 (27%), Positives = 95/254 (37%), Gaps = 38/254 (14%)

Query: 79  NPPSQTKLQARA----PNPTATSPPASAPRTAMRL---PAGRATLLPMPLSGRLAKASTP 131
           NP S +   A A    P P    PP+S      RL   PA    LLP  L+G  A A T 
Sbjct: 36  NPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRAAPAAAPRLLPRVLAG--APARTG 93

Query: 132 ALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLS-----VVLEALVPLK 186
           ALA         ++  Q +A     A  G      PG  P ++             VP  
Sbjct: 94  ALAGSRLRAAAAAAHDQEAA-----APTGRRWRRRPGPSPPLQPRSRHPHTRYPRAVPEA 148

Query: 187 TPM-PCLGAKHKAQSLQ-LSLADSPLKLRKSSGKGP--GNPRPKAPRKTTSKGPKCLTRK 242
           TP+ P  G + +A+S      +  P + R     GP  G+PRP+APR             
Sbjct: 149 TPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPR------------- 195

Query: 243 GPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVART 302
            PG  PRR    +   + +  SP  R  K  +  GT T Q +         R +    RT
Sbjct: 196 -PGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGT-TPQPQPPPPPCATRREEDMALRT 253

Query: 303 QAKAAKARAKAKAA 316
           + + +      +AA
Sbjct: 254 RDRTSSRGTVFRAA 267


>gi|239745455 PREDICTED: hypothetical protein XP_002343496 [Homo
           sapiens]
          Length = 304

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 56/202 (27%), Positives = 81/202 (40%), Gaps = 17/202 (8%)

Query: 213 RKSSGKGPGNPRPKAP-RKTTSKGPKCLTRKGPGAGPRRGSGHQSKTNRATGSPSVRRMK 271
           R   G GPG   P+A  R     G +C TR G G  P  GSG +   +R   SPS  R  
Sbjct: 77  RSPRGAGPGAAGPRAAGRGGAGGGGRCCTR-GRGRFPCAGSGGRGARSRGCHSPSCCR-- 133

Query: 272 GGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAA-QVKAKAKAKAAQVK 330
                 +  A  +  +   + A  +A  A     A + R    AA  + A+A A  A  +
Sbjct: 134 -----SSSCAWHRWPQLRGREAEPRASPALLICIAPRPRPALPAALHIGARATAGLAAKR 188

Query: 331 AKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRKGQKNRPETVGQKR 390
           A+ ++ +A   A+ +    R +A    T P  R RP G       R G +    T  +  
Sbjct: 189 AQPQLCSAGTAARGR----RTRAS-PPTPP--RPRPPGLRSGDVPRGGARVERPTGRRGA 241

Query: 391 KRAEEAKDLPPKKRTRLGPRSP 412
                A+ +PP+   RL P  P
Sbjct: 242 GGRGGAQRIPPRPLRRLVPIHP 263


>gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens]
          Length = 360

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 46/255 (18%), Positives = 95/255 (37%), Gaps = 9/255 (3%)

Query: 200 SLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAG-PRRGSGHQSKT 258
           +L++  A +   +R    +GP      A       G   +  KG GA  P R +   +  
Sbjct: 36  ALEVGAASADTGVRGCGARGPAPLLASAGGGRARDGTWGVRTKGSGAALPSRPASRAAPR 95

Query: 259 NRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQV 318
             A+  P       G   G +  +A+ A     + +     +R++ + ++ R K      
Sbjct: 96  PEASSPPLPLEKARGGLSGPQGGRARGAMAHVGSRKRSRSRSRSRGRGSEKRKKKSRKDT 155

Query: 319 KAKAKAKAAQVKAKAKVMAAWA--------KAKAKAKAVRAKAKVARTQPRGRGRPKGSA 370
                A  +Q +  +    A A        ++K KA+     +  + +          S+
Sbjct: 156 SRNCSASTSQGRKASTAPGAEASPSPCITERSKQKARRRTRSSSSSSSSSSSSSSSSSSS 215

Query: 371 KARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPKAWLGPGTAKLLKFRAIK 430
            + ++  G+K R +   ++RK+ ++ K L  K + +   +  +A  GP   +  +    +
Sbjct: 216 SSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAEAQQVEALPGPSLDQWHRSAGEE 275

Query: 431 VDRRSSDDEVRQRAQ 445
            D     DE + R Q
Sbjct: 276 EDGPVLTDEQKSRIQ 290


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 59/237 (24%), Positives = 98/237 (41%), Gaps = 24/237 (10%)

Query: 194 AKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRG-- 251
           AK  A+      A SP K      K P  P  K+P K  +K P  +        P +   
Sbjct: 538 AKSPAEVKSPEKAKSPAK---EEAKSP--PEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA 592

Query: 252 -SGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKAR 310
            S  ++K+     SP     K  +   +   +   +    K+        + +AK+ +  
Sbjct: 593 KSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKA 652

Query: 311 AKAKAAQVKAKAKAKAAQVKAKAKV-------MAAWAKAKAKAKA-VRAKAKVA-RTQPR 361
              +  + K+  KAK+  VKA+AK        + A AK+  KAK+ V+ +AK   + +  
Sbjct: 653 KSPEKEEAKSPEKAKSP-VKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSP 711

Query: 362 GRGRPKGSAKARTTRKGQKNRPET----VGQKRKRAEEAKDLPPKKRTRLGPRSPKA 414
            +   K   KA++  K +   PE     V ++ K  E+AK   P+K   L  +SP+A
Sbjct: 712 VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKS--PEKAKTLDVKSPEA 766



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 48/206 (23%), Positives = 79/206 (38%), Gaps = 19/206 (9%)

Query: 195  KHKAQSLQLSLADSPLKLRKSSGKGPGNPRPK---------APRKTTSKGPKCLTRKGPG 245
            K + +  ++ + + P K  +   K P  P+ +         AP+K   K PK   +K P 
Sbjct: 825  KEEEKPQEVKVKEPPKKAEEE--KAPATPKTEEKKDSKKEEAPKKEAPK-PKVEEKKEPA 881

Query: 246  AGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAK 305
                + S  ++K   A     V   +       K A AKV        + + +VA+ +  
Sbjct: 882  VEKPKESKVEAKKEEAEDKKKVPTPE-------KEAPAKVEVKEDAKPKEKTEVAKKEPD 934

Query: 306  AAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGR 365
             AKA+  +K A+ K  A  K    + KAK      K +AKAK          ++P+    
Sbjct: 935  DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKA 994

Query: 366  PKGSAKARTTRKGQKNRPETVGQKRK 391
             K S+  +   K  +   E    K K
Sbjct: 995  EKSSSTDQKDSKPPEKATEDKAAKGK 1020



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 79/350 (22%), Positives = 129/350 (36%), Gaps = 49/350 (14%)

Query: 78  ANPPSQTKLQARAPNPT---ATSPP-ASAPRTAMRLPAGRATLLPMPLSGRLAKASTPAL 133
           A  P++ K   +A +P    A SPP A +P                  S    +A +PA 
Sbjct: 538 AKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAE 597

Query: 134 AKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPCLG 193
           AK  +     S +K+ + S A   +                  V  EA  P +   P   
Sbjct: 598 AK--SPEKAKSPVKEEAKSPAEAKS-----------------PVKEEAKSPAEVKSP--- 635

Query: 194 AKHKAQSLQLSLADSPLKLRKSSGKGPGNP-RPKAPRKTTSKGPKCLTRKGPGAGPRRGS 252
              KA+S     A SP K +    +   +P + K+P K  +K P+    K P        
Sbjct: 636 --EKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPE--KAKSPVKA----- 686

Query: 253 GHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKA------ 306
             ++K+     SP     K  S    K+   + A++  KA     + A+T  KA      
Sbjct: 687 --EAKSPEKAKSPVKEEAK--SPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKE 742

Query: 307 -AKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGR 365
            AK+  KAK+ +       K+ + K  AK  A     K   KA     +  ++  + +  
Sbjct: 743 EAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSP 802

Query: 366 PKGSAKARTTRKGQKNRPETVGQKRKRAEE--AKDLPPKKRTRLGPRSPK 413
            K  AKA      +K   ++  ++ ++ +E   K+ P K      P +PK
Sbjct: 803 LKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPK 852



 Score = 36.6 bits (83), Expect = 0.050
 Identities = 78/350 (22%), Positives = 118/350 (33%), Gaps = 45/350 (12%)

Query: 82   SQTKLQARAPNPTATSP---PASAPRTAMRLPAGRATLLPMPLSGRLAKASTPALAKHAT 138
            S  K +A++P   A SP    A +P  A       A       S    +A TP  AK   
Sbjct: 682  SPVKAEAKSPEK-AKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPV 740

Query: 139  TNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPM--PCLGAKH 196
                 S  K  S   A+   V  P                 EA  P K     P      
Sbjct: 741  KEEAKSPEKAKSPEKAKTLDVKSP-----------------EAKTPAKEEARSPADKFPE 783

Query: 197  KAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQS 256
            KA+S       SP K +    +    P  + P+K   K P     K P     +    ++
Sbjct: 784  KAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK-PQEVKVKEPPKKA 842

Query: 257  KTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKA- 315
            +  +A  +P     K          +A   +   K   A  K   ++ +A K  A+ K  
Sbjct: 843  EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902

Query: 316  ---------AQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQP------ 360
                     A+V+ K  AK  +    AK     AKAK  +K    K      +       
Sbjct: 903  VPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKA 962

Query: 361  -RGRGRPKGSAKAR---TTRKGQKNRPETVGQKRKRAEEAKD-LPPKKRT 405
             +   +PK  AKA+    T   + ++P+    ++  + + KD  PP+K T
Sbjct: 963  KKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKAT 1012



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 65/259 (25%), Positives = 100/259 (38%), Gaps = 44/259 (16%)

Query: 180 EALVPLKTPMPCLGAKHKAQSLQLSLADSPLKLRKSS---GKGPGNPRPKAPRKTTSKGP 236
           EA  P K   P      KA++     A SP+K    S    K P     K+P K  +K P
Sbjct: 659 EAKSPEKAKSPV-----KAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEK--AKSP 711

Query: 237 KCLTRKGPGAGPRRGSGHQSKTNRATGSP------SVRRMKGGSALGTKTAQAKVARTLA 290
                K P    +     ++KT     SP      S  + K      T   ++  A+T A
Sbjct: 712 VKEEAKSPEKA-KSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPA 770

Query: 291 KA-ARAQAKVARTQAKA-----AKARAKAKAAQVKAKAKA------KAAQVKAKAKVMAA 338
           K  AR+ A     +AK+      K+  KAK+  +K  AKA      K  +VK+  K    
Sbjct: 771 KEEARSPADKFPEKAKSPVKEEVKSPEKAKSP-LKEDAKAPEKEIPKKEEVKSPVKEEEK 829

Query: 339 WAKAKAKAKAVRAKAKVARTQPRGRGR-------------PKGSAKARTTRKGQKNRPET 385
             + K K    +A+ + A   P+   +             PK   + +     +K +   
Sbjct: 830 PQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESK 889

Query: 386 VGQKRKRAEEAKDLP-PKK 403
           V  K++ AE+ K +P P+K
Sbjct: 890 VEAKKEEAEDKKKVPTPEK 908



 Score = 33.5 bits (75), Expect = 0.42
 Identities = 36/141 (25%), Positives = 60/141 (42%), Gaps = 11/141 (7%)

Query: 278 TKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKA---AQVKAKAKAKA-AQVKAKA 333
           TK+  A+ A +  K A++  K        AK+  K +A   A+VK+  KAK+ A+ +AK+
Sbjct: 501 TKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS 560

Query: 334 KVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRKGQKNRPETVGQKRKRA 393
                  +AK+  K         ++  + +   K  AK+    K  +     V ++ K  
Sbjct: 561 P-----PEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSP 615

Query: 394 EEAKDLPPKKRTRLGPRSPKA 414
            EAK   P K     P   K+
Sbjct: 616 AEAKS--PVKEEAKSPAEVKS 634



 Score = 32.3 bits (72), Expect = 0.94
 Identities = 41/193 (21%), Positives = 75/193 (38%), Gaps = 9/193 (4%)

Query: 233 SKGPKCLTRKGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKA 292
           +K P       P    +     ++K+     SP     K  + + +       A+  AK+
Sbjct: 501 TKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS 560

Query: 293 ARAQAKVARTQAKAAKARAKAKAAQVKAKAKAKA-AQVKAKAKVMAAWAKAKAKAKAVRA 351
                   + +AK+       + A+  AK +AK+ A+ K+  K   A +  K +AK+   
Sbjct: 561 PPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEK---AKSPVKEEAKSPAE 617

Query: 352 KAKVARTQPRGRGRPKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRT--RLGP 409
                + + +     K   KA++  K +   PE    K    EEAK  P K ++  +   
Sbjct: 618 AKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKA--KSPEKEEAKS-PEKAKSPVKAEA 674

Query: 410 RSPKAWLGPGTAK 422
           +SP+    P  A+
Sbjct: 675 KSPEKAKSPVKAE 687


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 69/343 (20%), Positives = 115/343 (33%), Gaps = 29/343 (8%)

Query: 74  SSCTANPPSQTKLQARAPN------------PTATSPPASAPRTAMRLPAGRATLLPMPL 121
           +S T + P+ T  +  AP             P  T+P  +AP T ++ PA      P P 
Sbjct: 608 TSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP-TTLKEPAPTTPKKPAPK 666

Query: 122 SGRLAKASTPALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEA 181
              LA  +T       +     ++ K+++ +  +  A   P    P   P        E 
Sbjct: 667 E--LAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT-PETPPPTTSEV 723

Query: 182 LVPLKTPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTR 241
             P  T  P    K   +S     A+   K  ++S K PG P  K P  T    P+  T 
Sbjct: 724 STPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK---PEMTT- 779

Query: 242 KGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVAR 301
                   + +    +T   T + + +  K  +    KT ++K+      A   Q     
Sbjct: 780 ----TAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKIT-----ATTTQVTSTT 830

Query: 302 TQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPR 361
           TQ          K   +  K       +     +      AK K +A  +KA   + Q  
Sbjct: 831 TQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKP 890

Query: 362 GRGRPKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKR 404
            +   K ++  +     +  +P+T    RK      +L P  R
Sbjct: 891 TKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSR 933



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 45/195 (23%), Positives = 70/195 (35%), Gaps = 11/195 (5%)

Query: 74  SSCTANPPSQTKLQARAPNPTATSPPA--SAPRTAMRLPAGRATLLPMPLSGRLAKASTP 131
           +S T   P+ T +++    P   +P    SAP T    PA   T  P P + +    +T 
Sbjct: 225 ASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE-PAPTTTKEPAPTTPKEPAPTTT 283

Query: 132 ALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPC 191
                 TT    ++ K+ + +  +  A   P    P        +   E     K P P 
Sbjct: 284 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 343

Query: 192 LGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRG 251
              K  A +       +P K   ++ K P    PK P  TT+K P   T K P     + 
Sbjct: 344 T-PKEPAPT-------APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 395

Query: 252 SGHQSKTNRATGSPS 266
           +   +K    T + S
Sbjct: 396 APTTTKEPAPTTTKS 410



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 64/300 (21%), Positives = 95/300 (31%), Gaps = 31/300 (10%)

Query: 80  PPSQTKLQARAPNPTATSPPASAPRTAMRLPAGRATLLPMPLSGRLAKASTPALAKHATT 139
           P   T    + P PT   P  + P+     PA  A   P P + +    +TP      TT
Sbjct: 322 PKEPTPTTPKEPAPTTKEPAPTTPKE----PAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 377

Query: 140 NLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPCLGAKHKAQ 199
                  K+ S +  +  A    T   P        +    A    K P P    +    
Sbjct: 378 -------KEPSPTTPKEPAPT-TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 429

Query: 200 SLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSKTN 259
           + +     +P K   ++ K P    PK P  TT+K P   T K P             T 
Sbjct: 430 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA----------PTTP 479

Query: 260 RATGSPSVRRMKGGSALGTKTAQAKVARTLAK--AARAQAKVARTQAKAAKARAKAKAAQ 317
           + T   + +++       T T   K+A T  +  A     ++A T  +        + A 
Sbjct: 480 KETAPTTPKKL-------TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 532

Query: 318 VKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRK 377
              KA A     +         A    K  A     + A T P+G         A TT K
Sbjct: 533 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 592



 Score = 33.5 bits (75), Expect = 0.42
 Identities = 51/220 (23%), Positives = 62/220 (28%), Gaps = 15/220 (6%)

Query: 209 PLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSK------TNRAT 262
           P    +++ KGP    PK P  TT K P   T K P     + +    K      T  A 
Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 256

Query: 263 GSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQVKAKA 322
            +P              T +     T  + A    K A T  K        K A    K 
Sbjct: 257 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 316

Query: 323 KAKA-------AQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPR--GRGRPKGSAKAR 373
            A            K  A      A    K  A  A  K A T P+      PK  A   
Sbjct: 317 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 376

Query: 374 TTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPK 413
           T         E      K A      P    T+  P +PK
Sbjct: 377 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 416



 Score = 33.1 bits (74), Expect = 0.55
 Identities = 73/348 (20%), Positives = 105/348 (30%), Gaps = 45/348 (12%)

Query: 77  TANPPSQTKLQA-----------RAPNPTATSPPASAPRTAMRLPAGRATLLPMPLSGRL 125
           T + P+ TK  A           + P+PT T  PA    T  + PA      P P + + 
Sbjct: 393 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP---TTPKEPAPTTPKKPAPTTPKE 449

Query: 126 AKASTPALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPL 185
              +TP      TT       K+ + +  +  A   P    P   P        E L P 
Sbjct: 450 PAPTTPKEPAPTTT-------KKPAPTTPKEPAPTTPKETAP-TTPKKLTPTTPEKLAPT 501

Query: 186 KTPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPG 245
               P   A    + L  +  + P     ++ + P    PKA    T K P   T K P 
Sbjct: 502 TPEKP---APTTPEELAPTTPEEP---TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 555

Query: 246 AGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAK 305
               +     +    A  +P           GT     K          A  ++A T  K
Sbjct: 556 PTTPKEPAPTTPKETAPTTPK----------GTAPTTLKEPAPTTPKKPAPKELAPTTTK 605

Query: 306 AAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGR 365
              +    K A    K  A     +         A    K  A     + A T P+   +
Sbjct: 606 EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK---K 662

Query: 366 PKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPK 413
           P     A TT KG    P +    +      K+  P       P +PK
Sbjct: 663 PAPKELAPTTTKG----PTSTTSDKPAPTTPKETAPTTPKEPAPTTPK 706


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 69/343 (20%), Positives = 115/343 (33%), Gaps = 29/343 (8%)

Query: 74  SSCTANPPSQTKLQARAPN------------PTATSPPASAPRTAMRLPAGRATLLPMPL 121
           +S T + P+ T  +  AP             P  T+P  +AP T ++ PA      P P 
Sbjct: 649 TSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP-TTLKEPAPTTPKKPAPK 707

Query: 122 SGRLAKASTPALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEA 181
              LA  +T       +     ++ K+++ +  +  A   P    P   P        E 
Sbjct: 708 E--LAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT-PETPPPTTSEV 764

Query: 182 LVPLKTPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTR 241
             P  T  P    K   +S     A+   K  ++S K PG P  K P  T    P+  T 
Sbjct: 765 STPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK---PEMTT- 820

Query: 242 KGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVAR 301
                   + +    +T   T + + +  K  +    KT ++K+      A   Q     
Sbjct: 821 ----TAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKIT-----ATTTQVTSTT 871

Query: 302 TQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPR 361
           TQ          K   +  K       +     +      AK K +A  +KA   + Q  
Sbjct: 872 TQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKP 931

Query: 362 GRGRPKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKR 404
            +   K ++  +     +  +P+T    RK      +L P  R
Sbjct: 932 TKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSR 974



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 45/195 (23%), Positives = 70/195 (35%), Gaps = 11/195 (5%)

Query: 74  SSCTANPPSQTKLQARAPNPTATSPPA--SAPRTAMRLPAGRATLLPMPLSGRLAKASTP 131
           +S T   P+ T +++    P   +P    SAP T    PA   T  P P + +    +T 
Sbjct: 266 ASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE-PAPTTTKEPAPTTPKEPAPTTT 324

Query: 132 ALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPC 191
                 TT    ++ K+ + +  +  A   P    P        +   E     K P P 
Sbjct: 325 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 384

Query: 192 LGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRG 251
              K  A +       +P K   ++ K P    PK P  TT+K P   T K P     + 
Sbjct: 385 T-PKEPAPT-------APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 436

Query: 252 SGHQSKTNRATGSPS 266
           +   +K    T + S
Sbjct: 437 APTTTKEPAPTTTKS 451



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 64/300 (21%), Positives = 95/300 (31%), Gaps = 31/300 (10%)

Query: 80  PPSQTKLQARAPNPTATSPPASAPRTAMRLPAGRATLLPMPLSGRLAKASTPALAKHATT 139
           P   T    + P PT   P  + P+     PA  A   P P + +    +TP      TT
Sbjct: 363 PKEPTPTTPKEPAPTTKEPAPTTPKE----PAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 418

Query: 140 NLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPCLGAKHKAQ 199
                  K+ S +  +  A    T   P        +    A    K P P    +    
Sbjct: 419 -------KEPSPTTPKEPAPT-TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 470

Query: 200 SLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSKTN 259
           + +     +P K   ++ K P    PK P  TT+K P   T K P             T 
Sbjct: 471 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA----------PTTP 520

Query: 260 RATGSPSVRRMKGGSALGTKTAQAKVARTLAK--AARAQAKVARTQAKAAKARAKAKAAQ 317
           + T   + +++       T T   K+A T  +  A     ++A T  +        + A 
Sbjct: 521 KETAPTTPKKL-------TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 573

Query: 318 VKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRK 377
              KA A     +         A    K  A     + A T P+G         A TT K
Sbjct: 574 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 633



 Score = 33.5 bits (75), Expect = 0.42
 Identities = 51/220 (23%), Positives = 62/220 (28%), Gaps = 15/220 (6%)

Query: 209 PLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSK------TNRAT 262
           P    +++ KGP    PK P  TT K P   T K P     + +    K      T  A 
Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 297

Query: 263 GSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQVKAKA 322
            +P              T +     T  + A    K A T  K        K A    K 
Sbjct: 298 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 357

Query: 323 KAKA-------AQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPR--GRGRPKGSAKAR 373
            A            K  A      A    K  A  A  K A T P+      PK  A   
Sbjct: 358 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 417

Query: 374 TTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPK 413
           T         E      K A      P    T+  P +PK
Sbjct: 418 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 457



 Score = 33.1 bits (74), Expect = 0.55
 Identities = 73/348 (20%), Positives = 105/348 (30%), Gaps = 45/348 (12%)

Query: 77  TANPPSQTKLQA-----------RAPNPTATSPPASAPRTAMRLPAGRATLLPMPLSGRL 125
           T + P+ TK  A           + P+PT T  PA    T  + PA      P P + + 
Sbjct: 434 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP---TTPKEPAPTTPKKPAPTTPKE 490

Query: 126 AKASTPALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPL 185
              +TP      TT       K+ + +  +  A   P    P   P        E L P 
Sbjct: 491 PAPTTPKEPAPTTT-------KKPAPTTPKEPAPTTPKETAP-TTPKKLTPTTPEKLAPT 542

Query: 186 KTPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPG 245
               P   A    + L  +  + P     ++ + P    PKA    T K P   T K P 
Sbjct: 543 TPEKP---APTTPEELAPTTPEEP---TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 596

Query: 246 AGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAK 305
               +     +    A  +P           GT     K          A  ++A T  K
Sbjct: 597 PTTPKEPAPTTPKETAPTTPK----------GTAPTTLKEPAPTTPKKPAPKELAPTTTK 646

Query: 306 AAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGR 365
              +    K A    K  A     +         A    K  A     + A T P+   +
Sbjct: 647 EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK---K 703

Query: 366 PKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPK 413
           P     A TT KG    P +    +      K+  P       P +PK
Sbjct: 704 PAPKELAPTTTKG----PTSTTSDKPAPTTPKETAPTTPKEPAPTTPK 747


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 69/343 (20%), Positives = 115/343 (33%), Gaps = 29/343 (8%)

Query: 74   SSCTANPPSQTKLQARAPN------------PTATSPPASAPRTAMRLPAGRATLLPMPL 121
            +S T + P+ T  +  AP             P  T+P  +AP T ++ PA      P P 
Sbjct: 701  TSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP-TTLKEPAPTTPKKPAPK 759

Query: 122  SGRLAKASTPALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEA 181
               LA  +T       +     ++ K+++ +  +  A   P    P   P        E 
Sbjct: 760  E--LAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT-PETPPPTTSEV 816

Query: 182  LVPLKTPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTR 241
              P  T  P    K   +S     A+   K  ++S K PG P  K P  T    P+  T 
Sbjct: 817  STPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK---PEMTT- 872

Query: 242  KGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVAR 301
                    + +    +T   T + + +  K  +    KT ++K+      A   Q     
Sbjct: 873  ----TAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKIT-----ATTTQVTSTT 923

Query: 302  TQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPR 361
            TQ          K   +  K       +     +      AK K +A  +KA   + Q  
Sbjct: 924  TQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKP 983

Query: 362  GRGRPKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKR 404
             +   K ++  +     +  +P+T    RK      +L P  R
Sbjct: 984  TKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSR 1026



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 45/195 (23%), Positives = 70/195 (35%), Gaps = 11/195 (5%)

Query: 74  SSCTANPPSQTKLQARAPNPTATSPPA--SAPRTAMRLPAGRATLLPMPLSGRLAKASTP 131
           +S T   P+ T +++    P   +P    SAP T    PA   T  P P + +    +T 
Sbjct: 318 ASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE-PAPTTTKEPAPTTPKEPAPTTT 376

Query: 132 ALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPC 191
                 TT    ++ K+ + +  +  A   P    P        +   E     K P P 
Sbjct: 377 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 436

Query: 192 LGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRG 251
              K  A +       +P K   ++ K P    PK P  TT+K P   T K P     + 
Sbjct: 437 T-PKEPAPT-------APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 488

Query: 252 SGHQSKTNRATGSPS 266
           +   +K    T + S
Sbjct: 489 APTTTKEPAPTTTKS 503



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 64/300 (21%), Positives = 95/300 (31%), Gaps = 31/300 (10%)

Query: 80  PPSQTKLQARAPNPTATSPPASAPRTAMRLPAGRATLLPMPLSGRLAKASTPALAKHATT 139
           P   T    + P PT   P  + P+     PA  A   P P + +    +TP      TT
Sbjct: 415 PKEPTPTTPKEPAPTTKEPAPTTPKE----PAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 470

Query: 140 NLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPCLGAKHKAQ 199
                  K+ S +  +  A    T   P        +    A    K P P    +    
Sbjct: 471 -------KEPSPTTPKEPAPT-TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 522

Query: 200 SLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSKTN 259
           + +     +P K   ++ K P    PK P  TT+K P   T K P             T 
Sbjct: 523 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA----------PTTP 572

Query: 260 RATGSPSVRRMKGGSALGTKTAQAKVARTLAK--AARAQAKVARTQAKAAKARAKAKAAQ 317
           + T   + +++       T T   K+A T  +  A     ++A T  +        + A 
Sbjct: 573 KETAPTTPKKL-------TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 625

Query: 318 VKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRK 377
              KA A     +         A    K  A     + A T P+G         A TT K
Sbjct: 626 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 685



 Score = 33.5 bits (75), Expect = 0.42
 Identities = 51/220 (23%), Positives = 62/220 (28%), Gaps = 15/220 (6%)

Query: 209 PLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSK------TNRAT 262
           P    +++ KGP    PK P  TT K P   T K P     + +    K      T  A 
Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 349

Query: 263 GSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQVKAKA 322
            +P              T +     T  + A    K A T  K        K A    K 
Sbjct: 350 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 409

Query: 323 KAKA-------AQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPR--GRGRPKGSAKAR 373
            A            K  A      A    K  A  A  K A T P+      PK  A   
Sbjct: 410 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 469

Query: 374 TTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPK 413
           T         E      K A      P    T+  P +PK
Sbjct: 470 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 509



 Score = 33.1 bits (74), Expect = 0.55
 Identities = 73/348 (20%), Positives = 105/348 (30%), Gaps = 45/348 (12%)

Query: 77  TANPPSQTKLQA-----------RAPNPTATSPPASAPRTAMRLPAGRATLLPMPLSGRL 125
           T + P+ TK  A           + P+PT T  PA    T  + PA      P P + + 
Sbjct: 486 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP---TTPKEPAPTTPKKPAPTTPKE 542

Query: 126 AKASTPALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPL 185
              +TP      TT       K+ + +  +  A   P    P   P        E L P 
Sbjct: 543 PAPTTPKEPAPTTT-------KKPAPTTPKEPAPTTPKETAP-TTPKKLTPTTPEKLAPT 594

Query: 186 KTPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPG 245
               P   A    + L  +  + P     ++ + P    PKA    T K P   T K P 
Sbjct: 595 TPEKP---APTTPEELAPTTPEEP---TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 648

Query: 246 AGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAK 305
               +     +    A  +P           GT     K          A  ++A T  K
Sbjct: 649 PTTPKEPAPTTPKETAPTTPK----------GTAPTTLKEPAPTTPKKPAPKELAPTTTK 698

Query: 306 AAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGR 365
              +    K A    K  A     +         A    K  A     + A T P+   +
Sbjct: 699 EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK---K 755

Query: 366 PKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPK 413
           P     A TT KG    P +    +      K+  P       P +PK
Sbjct: 756 PAPKELAPTTTKG----PTSTTSDKPAPTTPKETAPTTPKEPAPTTPK 799


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 69/343 (20%), Positives = 115/343 (33%), Gaps = 29/343 (8%)

Query: 74   SSCTANPPSQTKLQARAPN------------PTATSPPASAPRTAMRLPAGRATLLPMPL 121
            +S T + P+ T  +  AP             P  T+P  +AP T ++ PA      P P 
Sbjct: 742  TSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP-TTLKEPAPTTPKKPAPK 800

Query: 122  SGRLAKASTPALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEA 181
               LA  +T       +     ++ K+++ +  +  A   P    P   P        E 
Sbjct: 801  E--LAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT-PETPPPTTSEV 857

Query: 182  LVPLKTPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTR 241
              P  T  P    K   +S     A+   K  ++S K PG P  K P  T    P+  T 
Sbjct: 858  STPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK---PEMTT- 913

Query: 242  KGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVAR 301
                    + +    +T   T + + +  K  +    KT ++K+      A   Q     
Sbjct: 914  ----TAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKIT-----ATTTQVTSTT 964

Query: 302  TQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPR 361
            TQ          K   +  K       +     +      AK K +A  +KA   + Q  
Sbjct: 965  TQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKP 1024

Query: 362  GRGRPKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKR 404
             +   K ++  +     +  +P+T    RK      +L P  R
Sbjct: 1025 TKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSR 1067



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 45/195 (23%), Positives = 70/195 (35%), Gaps = 11/195 (5%)

Query: 74  SSCTANPPSQTKLQARAPNPTATSPPA--SAPRTAMRLPAGRATLLPMPLSGRLAKASTP 131
           +S T   P+ T +++    P   +P    SAP T    PA   T  P P + +    +T 
Sbjct: 359 ASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE-PAPTTTKEPAPTTPKEPAPTTT 417

Query: 132 ALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPC 191
                 TT    ++ K+ + +  +  A   P    P        +   E     K P P 
Sbjct: 418 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 477

Query: 192 LGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRG 251
              K  A +       +P K   ++ K P    PK P  TT+K P   T K P     + 
Sbjct: 478 T-PKEPAPT-------APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 529

Query: 252 SGHQSKTNRATGSPS 266
           +   +K    T + S
Sbjct: 530 APTTTKEPAPTTTKS 544



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 64/300 (21%), Positives = 95/300 (31%), Gaps = 31/300 (10%)

Query: 80  PPSQTKLQARAPNPTATSPPASAPRTAMRLPAGRATLLPMPLSGRLAKASTPALAKHATT 139
           P   T    + P PT   P  + P+     PA  A   P P + +    +TP      TT
Sbjct: 456 PKEPTPTTPKEPAPTTKEPAPTTPKE----PAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 511

Query: 140 NLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPCLGAKHKAQ 199
                  K+ S +  +  A    T   P        +    A    K P P    +    
Sbjct: 512 -------KEPSPTTPKEPAPT-TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 563

Query: 200 SLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSKTN 259
           + +     +P K   ++ K P    PK P  TT+K P   T K P             T 
Sbjct: 564 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA----------PTTP 613

Query: 260 RATGSPSVRRMKGGSALGTKTAQAKVARTLAK--AARAQAKVARTQAKAAKARAKAKAAQ 317
           + T   + +++       T T   K+A T  +  A     ++A T  +        + A 
Sbjct: 614 KETAPTTPKKL-------TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 666

Query: 318 VKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRK 377
              KA A     +         A    K  A     + A T P+G         A TT K
Sbjct: 667 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 726



 Score = 33.5 bits (75), Expect = 0.42
 Identities = 51/220 (23%), Positives = 62/220 (28%), Gaps = 15/220 (6%)

Query: 209 PLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSK------TNRAT 262
           P    +++ KGP    PK P  TT K P   T K P     + +    K      T  A 
Sbjct: 331 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 390

Query: 263 GSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQVKAKA 322
            +P              T +     T  + A    K A T  K        K A    K 
Sbjct: 391 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 450

Query: 323 KAKA-------AQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPR--GRGRPKGSAKAR 373
            A            K  A      A    K  A  A  K A T P+      PK  A   
Sbjct: 451 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 510

Query: 374 TTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPK 413
           T         E      K A      P    T+  P +PK
Sbjct: 511 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 550



 Score = 33.1 bits (74), Expect = 0.55
 Identities = 73/348 (20%), Positives = 105/348 (30%), Gaps = 45/348 (12%)

Query: 77  TANPPSQTKLQA-----------RAPNPTATSPPASAPRTAMRLPAGRATLLPMPLSGRL 125
           T + P+ TK  A           + P+PT T  PA    T  + PA      P P + + 
Sbjct: 527 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP---TTPKEPAPTTPKKPAPTTPKE 583

Query: 126 AKASTPALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPL 185
              +TP      TT       K+ + +  +  A   P    P   P        E L P 
Sbjct: 584 PAPTTPKEPAPTTT-------KKPAPTTPKEPAPTTPKETAP-TTPKKLTPTTPEKLAPT 635

Query: 186 KTPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPG 245
               P   A    + L  +  + P     ++ + P    PKA    T K P   T K P 
Sbjct: 636 TPEKP---APTTPEELAPTTPEEP---TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 689

Query: 246 AGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAK 305
               +     +    A  +P           GT     K          A  ++A T  K
Sbjct: 690 PTTPKEPAPTTPKETAPTTPK----------GTAPTTLKEPAPTTPKKPAPKELAPTTTK 739

Query: 306 AAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGR 365
              +    K A    K  A     +         A    K  A     + A T P+   +
Sbjct: 740 EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK---K 796

Query: 366 PKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPK 413
           P     A TT KG    P +    +      K+  P       P +PK
Sbjct: 797 PAPKELAPTTTKG----PTSTTSDKPAPTTPKETAPTTPKEPAPTTPK 840


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 61/317 (19%), Positives = 119/317 (37%), Gaps = 47/317 (14%)

Query: 59  GFQPTILRSGDVYGYSSCTANPPSQTKLQARAPNPTATSPPASAPRTAMRLPAGRATLLP 118
           G Q  + R  D     S ++   S +  + +     AT+ P +  + A+ LPA +A    
Sbjct: 412 GGQKLLTRKAD-----SSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQA---- 462

Query: 119 MPLSGRLAKASTPALAKHATTNLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVV 178
                       P  ++ ++++   SS ++     ++ A    P  +  G  P+      
Sbjct: 463 ------------PQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSK----- 505

Query: 179 LEALVPLKTPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKC 238
                      P    K KA+S   S +D   +  +   KG G+PRP+AP+   + G   
Sbjct: 506 -----------PASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPK---ANGTSA 551

Query: 239 LTRKGPGAGPRRGSGHQSKTNRA---TGSPSVRRMK-GGSALGTKTAQAKVARTLAKAAR 294
           LT +   A        + K   A   + S S+++ K   +A   +T QAK  +   +   
Sbjct: 552 LTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAK--KIKLQTPN 609

Query: 295 AQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWA-KAKAKAKAVRAKA 353
              K  + + +A+    + +  +++  ++       AK      W  +A    K  + K+
Sbjct: 610 TFPKRKKGEKRASSPFRRVREEEIEVDSRVADNSFDAKRGAAGDWGERANQVLKFTKGKS 669

Query: 354 KVARTQPRGRGRPKGSA 370
                  + RG  +G +
Sbjct: 670 FRHEKTKKKRGSYRGGS 686



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 34/124 (27%), Positives = 52/124 (41%), Gaps = 10/124 (8%)

Query: 294 RAQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKA 353
           +AQ K     A+AA   A  KAA   + + + ++   ++ +  AA  K     K V AKA
Sbjct: 193 KAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKA 252

Query: 354 KV-ARTQPRGR---GRPKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGP 409
            V A T P  +        S +    +K  KN+P         +      PP K++ LG 
Sbjct: 253 PVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYS-----SVPPPSAPPPKKS-LGT 306

Query: 410 RSPK 413
           + PK
Sbjct: 307 QPPK 310



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 76/341 (22%), Positives = 115/341 (33%), Gaps = 74/341 (21%)

Query: 83  QTKLQARAPNPTATSPPASAPRTAMRL---PAGRATLLPMPLSGRLAKASTPALAKHATT 139
           Q K     P P ++ PP SAP     L   P  +A     P+                  
Sbjct: 278 QKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVE----------------- 320

Query: 140 NLLLSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPCLGAKHKAQ 199
               SS   S  S +       P                 +A+V   T  P    K    
Sbjct: 321 ----SSEDSSDESDSSSEEEKKPP---------------TKAVVSKATTKPPPAKKAAES 361

Query: 200 SLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRK---GPGAGPRR--GSGH 254
           S   S +D       SS       +P    K +S  P   T+     P A P++  G G 
Sbjct: 362 SSDSSDSD-------SSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQ 414

Query: 255 QSKTNRATGSPSVRRMKGGSALGTK--TAQAKVARTLAKAARAQAKVARTQAKAAKARAK 312
           +  T +A  S S           TK   A  K   T   A    AK A   ++ + + + 
Sbjct: 415 KLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSD 474

Query: 313 AKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQP------------ 360
           + +++ + +  +K+A VK K + +A  A     A A + KA+ + +              
Sbjct: 475 SSSSEEEEEKTSKSA-VKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKL 533

Query: 361 RGRGRPKGSA-KARTTR-------KGQKNRPETVGQKRKRA 393
           +G+G P+  A KA  T        K  KN  E   +K+K A
Sbjct: 534 KGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAA 574


>gi|50409691 SRp25 nuclear protein isoform 4 [Homo sapiens]
          Length = 338

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 44/247 (17%), Positives = 96/247 (38%), Gaps = 12/247 (4%)

Query: 200 SLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAG-PRRGSGHQSKT 258
           +L++  A +   +R    +GP      A       G   +  KG GA  P R +   +  
Sbjct: 36  ALEVGAASADTGVRGCGARGPAPLLASAGGGRARDGTWGVRTKGSGAALPSRPASRAAPR 95

Query: 259 NRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQV 318
             A+  P       G   G +  +A+ A     + +     +R++ + ++ R K      
Sbjct: 96  PEASSPPLPLEKARGGLSGPQGGRARGAMAHVGSRKRSRSRSRSRGRGSEKRKKKSRKDT 155

Query: 319 KAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRKG 378
                A  +Q ++K K     A+ + ++ +  + +  + +          S+ + ++  G
Sbjct: 156 SRNCSASTSQERSKQK-----ARRRTRSSSSSSSSSSSSSSS------SSSSSSSSSSDG 204

Query: 379 QKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPKAWLGPGTAKLLKFRAIKVDRRSSDD 438
           +K R +   ++RK+ ++ K L  K + +   +  +A  GP   +  +    + D     D
Sbjct: 205 RKKRGKYKDKRRKKKKKRKKLKKKGKEKAEAQQVEALPGPSLDQWHRSAGEEEDGPVLTD 264

Query: 439 EVRQRAQ 445
           E + R Q
Sbjct: 265 EQKSRIQ 271


>gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens]
          Length = 341

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 44/247 (17%), Positives = 96/247 (38%), Gaps = 12/247 (4%)

Query: 200 SLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAG-PRRGSGHQSKT 258
           +L++  A +   +R    +GP      A       G   +  KG GA  P R +   +  
Sbjct: 36  ALEVGAASADTGVRGCGARGPAPLLASAGGGRARDGTWGVRTKGSGAALPSRPASRAAPR 95

Query: 259 NRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQV 318
             A+  P       G   G +  +A+ A     + +     +R++ + ++ R K      
Sbjct: 96  PEASSPPLPLEKARGGLSGPQGGRARGAMAHVGSRKRSRSRSRSRGRGSEKRKKKSRKDT 155

Query: 319 KAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRKG 378
                A  +Q ++K K     A+ + ++ +  + +  + +          S+ + ++  G
Sbjct: 156 SRNCSASTSQERSKQK-----ARRRTRSSSSSSSSSSSSSSS------SSSSSSSSSSDG 204

Query: 379 QKNRPETVGQKRKRAEEAKDLPPKKRTRLGPRSPKAWLGPGTAKLLKFRAIKVDRRSSDD 438
           +K R +   ++RK+ ++ K L  K + +   +  +A  GP   +  +    + D     D
Sbjct: 205 RKKRGKYKDKRRKKKKKRKKLKKKGKEKAEAQQVEALPGPSLDQWHRSAGEEEDGPVLTD 264

Query: 439 EVRQRAQ 445
           E + R Q
Sbjct: 265 EQKSRIQ 271


>gi|4885371 H1 histone family, member 0 [Homo sapiens]
          Length = 194

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 39/118 (33%), Positives = 56/118 (47%), Gaps = 9/118 (7%)

Query: 267 VRRMKGGSALGT----KTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQVKAKA 322
           +++ KG  A G+    K+ + K +    K  +   KVA T  KA+K +  A  A  K   
Sbjct: 81  LKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVA-TPKKASKPKKAASKAPTK--- 136

Query: 323 KAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRKGQK 380
           K KA  VK   K +AA  K   K K V+AK  V  ++P+     K  AK+   R G+K
Sbjct: 137 KPKATPVKKAKKKLAATPKKAKKPKTVKAK-PVKASKPKKAKPVKPKAKSSAKRAGKK 193



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 37/118 (31%), Positives = 56/118 (47%), Gaps = 12/118 (10%)

Query: 278 TKTAQAKVARTLAKAARAQAKVA--RTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKV 335
           TK   A  +  LAK+   +  VA  +T+ +  K     KA++ K KA +KA   K KA  
Sbjct: 84  TKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPK-KAASKAPTKKPKATP 142

Query: 336 MAAWAKAKAKAKAVRAKAKVART---QPRGRGRPKGSAKARTTRKGQKNRPETVGQKR 390
           +    KAK K  A   KAK  +T   +P    +PK   KA+  +   K+  +  G+K+
Sbjct: 143 VK---KAKKKLAATPKKAKKPKTVKAKPVKASKPK---KAKPVKPKAKSSAKRAGKKK 194


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 74/294 (25%), Positives = 108/294 (36%), Gaps = 48/294 (16%)

Query: 86  LQARAPNPTATSPPASAPRTAMRLPAGRATLLPM---PLSGRLAKASTPALAKHATTNLL 142
           L  RA      + P SAPR      AG ++  P    P SGR  +A     AK+ +   +
Sbjct: 58  LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPP---AKNTSPGPV 114

Query: 143 LSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPCLGAKHKAQSLQ 202
            S  + S  +              PG      L +  E  V          A+ KA    
Sbjct: 115 SSPGRASGTTR-------------PGPLGQKGLRISAEETV----------ARGKATEAP 151

Query: 203 LSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKC-LTRKGPGA-------GPRRGSGH 254
              A S    R +SG  PG P P   R++ + G +  L R  P A       GPR+    
Sbjct: 152 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 211

Query: 255 QSKTNRATGSPSVRRM-KGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKA 313
            S+ +    SP+ RR    G  L     Q   +R+L+ +A   +  AR+      AR   
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGL-----QRPASRSLSSSATPLSSPARS---GPSARGTP 263

Query: 314 KAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRG-RGRP 366
           +A    ++ K K  Q     +V     K  A A    + + +A   P G + RP
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPP-RKDAAPALGPLSSSPLATPSPSGTKARP 316



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 11/113 (9%)

Query: 80  PPSQTKLQARAPNPTATSPPASAPRTAMRLPAGRATLLPMPLSGRLAKASTPALAKHATT 139
           PPS T    +AP    T PP   P  ++  P+ +A   P+ LS   A  S  +    AT 
Sbjct: 369 PPSMTTPPMQAPPSLQTIPPIQVPH-SLTSPSLQAPPSPLALSSLQATTSLGSPTLQATH 427

Query: 140 NLLLSSLKQSSA---SHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPM 189
           + L  S +Q+ A   S +R A+        P   P ++  + L A  PL+T +
Sbjct: 428 SFLTMSPRQTQASLTSPSRPAST-------PPDSPPLQAPLSLPASPPLQTSL 473


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 66/249 (26%), Positives = 93/249 (37%), Gaps = 44/249 (17%)

Query: 86  LQARAPNPTATSPPASAPRTAMRLPAGRATLLPM---PLSGRLAKASTPALAKHATTNLL 142
           L  RA      + P SAPR      AG ++  P    P SGR  +A     AK+ +   +
Sbjct: 58  LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPP---AKNTSPGPV 114

Query: 143 LSSLKQSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLKTPMPCLGAKHKAQSLQ 202
            S  + S  +              PG      L +  E  V          A+ KA    
Sbjct: 115 SSPGRASGTTR-------------PGPLGQKGLRISAEETV----------ARGKATEAP 151

Query: 203 LSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPKC-LTRKGPGA-------GPRRGSGH 254
              A S    R +SG  PG P P   R++ + G +  L R  P A       GPR+    
Sbjct: 152 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 211

Query: 255 QSKTNRATGSPSVRRM-KGGSALGTKTAQAKVARTLAKAARAQAKVARTQAKA-AKARAK 312
            S+ +    SP+ RR    G  L     Q   +R+L+ +A   +  AR+   A    RA 
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGL-----QRPASRSLSSSATPLSSPARSGPSARGTPRAP 266

Query: 313 AKAAQVKAK 321
           A  +Q K K
Sbjct: 267 AHPSQPKPK 275


>gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo
           sapiens]
          Length = 351

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 59/251 (23%), Positives = 92/251 (36%), Gaps = 29/251 (11%)

Query: 187 TPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRPKAPRKTTSKGPK--------- 237
           TP P L     +   Q     + +    S G+G     P+     T   P+         
Sbjct: 66  TPAPALLLLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSAPRRCPYQDASR 125

Query: 238 -----CLTR---KGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTL 289
                C +R   +G G    R  G ++  +R  G    R  K   A G K    K  +  
Sbjct: 126 AGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGA-GAK----KHRKPR 180

Query: 290 AKAARAQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAV 349
            +  RA A   +   KAA A+++    +  A A  K  + +   K  AA ++     K  
Sbjct: 181 RRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQK--AAKSRGGGDKKLE 238

Query: 350 RAKAKVARTQPRGRGRP-KGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLG 408
           R KA +   + RG  +P +G  K R   +  K+R    G   ++ ++A     K R   G
Sbjct: 239 RQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSR----GGGGEKPQKAAAAGAKSRGGRG 294

Query: 409 PRSPKAWLGPG 419
            +  KA  G G
Sbjct: 295 EKPQKAEAGQG 305



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 76/329 (23%), Positives = 112/329 (34%), Gaps = 39/329 (11%)

Query: 68  GDVYGYSSCTANPPSQTKLQARAPNPTATSPPASAPRTAMRLPAGRATLLPMPLSGRLAK 127
           G+  G+S+  A P    +  A          PA   R A R P   ATL   P++     
Sbjct: 18  GEAVGHSALGAQPVQAAEGDA----DELLELPALLQRPAGRGPC--ATLRSHPIT----- 66

Query: 128 ASTPALAKHATTNLLLSSLK-QSSASHARGAAVGFPTHLYPGVYPAMRLSVVLEALVPLK 186
              PAL       LL  SL  Q  +  A  A  G P     G  P  R S    A  P +
Sbjct: 67  -PAPALL------LLSHSLPAQRRSMQATVAKAGSPGRGRLGKEPRRRESWTRSA--PRR 117

Query: 187 TPMPCLGAKHKAQSLQLSLADSPLKLRKSSGKGPGNPRP-----KAPRKTTSKGPKCLTR 241
            P               S A S +   +   +G G+ +P     KA +     G K   +
Sbjct: 118 CPYQ-----------DASRAGSRVCRSRPQNRGGGDKKPRRRGQKAAKSRGGGGKKPRGQ 166

Query: 242 KGPGAGPRRGSGHQSKTNRATGSPSVRRMKGGSALGTKTAQAKVARTLAKAARAQA--KV 299
           K  GAG ++    + +  RA  +   +  K  +A        K A    K  R +   K 
Sbjct: 167 KAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRRGQKA 226

Query: 300 ARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQ 359
           A+++    K   + KAA    K++     ++   K        K++        K A   
Sbjct: 227 AKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGKKQRERGQNTKSRGGGGEKPQKAAAAG 286

Query: 360 PRGRGRPKGSAKARTTRKGQKNRPETVGQ 388
            + RG      +     +GQ  R E  GQ
Sbjct: 287 AKSRGGRGEKPQKAEAGQGQNRRNEVGGQ 315



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 29/84 (34%), Positives = 41/84 (48%), Gaps = 6/84 (7%)

Query: 348 AVRAKAKVARTQPRGRGRPKGSAKARTTRKGQK-NRPETVGQKRKRAEEAKDLPPKKRTR 406
           A RA ++V R++P+ RG   G  K R  R+GQK  +    G K+ R ++A     KK  +
Sbjct: 123 ASRAGSRVCRSRPQNRGG--GDKKPR--RRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRK 178

Query: 407 LGPRSPKAWLGPGTAKLLKFRAIK 430
              R  +A    G  KL K  A K
Sbjct: 179 PRRRGERA-AAAGGKKLQKAAAAK 201


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 35/157 (22%), Positives = 76/157 (48%), Gaps = 13/157 (8%)

Query: 291  KAARAQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVR 350
            K    ++K  + + K  K + +  + + ++K ++K+++ K++ +     ++++++A+   
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSK-RSKSSEHKSRKRT----SESRSRARKRS 1851

Query: 351  AKAKVARTQPRGRGRPKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPR 410
            +K+K  R+Q R R R +   ++  +R   + R     +KRKR+       PK R++   R
Sbjct: 1852 SKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRS-------PKHRSKSRER 1904

Query: 411  SPKAWLGPGTAKLLKFRAIKVDRRS-SDDEVRQRAQR 446
              K        K ++ R+    RRS S    R+R  R
Sbjct: 1905 KRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSR 1941



 Score = 33.1 bits (74), Expect = 0.55
 Identities = 28/163 (17%), Positives = 70/163 (42%), Gaps = 2/163 (1%)

Query: 213  RKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSKTNRATGSPSVRRMKG 272
            RK S K     R +  ++++S+  +   R       RR   H     R + S   RR   
Sbjct: 1891 RKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFS 1950

Query: 273  GSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAK 332
             S        ++ +RT ++ +R  ++ +RT ++  ++R  ++ ++  ++ +   + V+ +
Sbjct: 1951 ISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR--RSRTPSRRSRTPSRRRRSRSVVRRR 2008

Query: 333  AKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTT 375
            +  ++     +++    R  ++    + R R   +G +  R T
Sbjct: 2009 SFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLT 2051


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 35/157 (22%), Positives = 76/157 (48%), Gaps = 13/157 (8%)

Query: 291  KAARAQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKVMAAWAKAKAKAKAVR 350
            K    ++K  + + K  K + +  + + ++K ++K+++ K++ +     ++++++A+   
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSK-RSKSSEHKSRKRT----SESRSRARKRS 1851

Query: 351  AKAKVARTQPRGRGRPKGSAKARTTRKGQKNRPETVGQKRKRAEEAKDLPPKKRTRLGPR 410
            +K+K  R+Q R R R +   ++  +R   + R     +KRKR+       PK R++   R
Sbjct: 1852 SKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRS-------PKHRSKSRER 1904

Query: 411  SPKAWLGPGTAKLLKFRAIKVDRRS-SDDEVRQRAQR 446
              K        K ++ R+    RRS S    R+R  R
Sbjct: 1905 KRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSR 1941



 Score = 33.1 bits (74), Expect = 0.55
 Identities = 28/163 (17%), Positives = 70/163 (42%), Gaps = 2/163 (1%)

Query: 213  RKSSGKGPGNPRPKAPRKTTSKGPKCLTRKGPGAGPRRGSGHQSKTNRATGSPSVRRMKG 272
            RK S K     R +  ++++S+  +   R       RR   H     R + S   RR   
Sbjct: 1891 RKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFS 1950

Query: 273  GSALGTKTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQVKAKAKAKAAQVKAK 332
             S        ++ +RT ++ +R  ++ +RT ++  ++R  ++ ++  ++ +   + V+ +
Sbjct: 1951 ISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR--RSRTPSRRSRTPSRRRRSRSVVRRR 2008

Query: 333  AKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTT 375
            +  ++     +++    R  ++    + R R   +G +  R T
Sbjct: 2009 SFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLT 2051


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.125    0.351 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,899,280
Number of Sequences: 37866
Number of extensions: 920968
Number of successful extensions: 6834
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 378
Number of HSP's that attempted gapping in prelim test: 5621
Number of HSP's gapped (non-prelim): 1184
length of query: 467
length of database: 18,247,518
effective HSP length: 106
effective length of query: 361
effective length of database: 14,233,722
effective search space: 5138373642
effective search space used: 5138373642
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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