Search of human proteins with 15208660

Search of human proteins with 15208660

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15208660 tripartite motif protein 21 [Homo sapiens]
         (475 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|15208660 tripartite motif protein 21 [Homo sapiens]                980   0.0  
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]    400   e-111
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]    400   e-111
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            384   e-106
gi|37622899 ring finger protein 137 [Homo sapiens]                    377   e-104
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]      371   e-103
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]      371   e-103
gi|51477690 tripartite motif-containing 6 and tripartite motif-c...   371   e-103
gi|117938316 tripartite motif-containing 22 [Homo sapiens]            357   1e-98
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   357   2e-98
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             352   3e-97
gi|5454014 tripartite motif-containing 38 [Homo sapiens]              350   2e-96
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s...   348   5e-96
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   344   1e-94
gi|5730009 ret finger protein [Homo sapiens]                          332   5e-91
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]   296   4e-80
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]    296   4e-80
gi|31542779 tripartite motif family-like 1 [Homo sapiens]             295   8e-80
gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]   273   2e-73
gi|22749269 ring finger protein 129 [Homo sapiens]                    270   3e-72
gi|157743261 tripartite motif-containing 75 [Homo sapiens]            269   4e-72
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa...   261   7e-70
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]    257   2e-68
gi|4557743 Mediterranean fever protein [Homo sapiens]                 253   3e-67
gi|210147600 tripartite motif-containing 64 [Homo sapiens]            248   1e-65
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s...   248   1e-65
gi|169202375 PREDICTED: tripartite motif-containing protein 64B-...   247   2e-65
gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo s...   245   7e-65
gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo s...   245   7e-65
gi|239755486 PREDICTED: tripartite motif-containing protein 64C-...   232   5e-61

>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  980 bits (2534), Expect = 0.0
 Identities = 475/475 (100%), Positives = 475/475 (100%)

Query: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLL 60
           MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLL
Sbjct: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLL 60

Query: 61  KNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKH 120
           KNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKH
Sbjct: 61  KNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKH 120

Query: 121 RDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHA 180
           RDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHA
Sbjct: 121 RDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHA 180

Query: 181 EFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSA 240
           EFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSA
Sbjct: 181 EFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSA 240

Query: 241 LELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWL 300
           LELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWL
Sbjct: 241 LELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWL 300

Query: 301 ILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCR 360
           ILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCR
Sbjct: 301 ILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCR 360

Query: 361 DSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSF 420
           DSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSF
Sbjct: 361 DSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSF 420

Query: 421 YNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY 475
           YNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY
Sbjct: 421 YNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY 475


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score =  400 bits (1029), Expect = e-111
 Identities = 215/466 (46%), Positives = 294/466 (63%), Gaps = 31/466 (6%)

Query: 12  EEVTCPICLDPFVEPVSIECGHSFCQECI------SQVGKGGGSVCPVCRQRFLLKNLRP 65
           EEVTCPICL+   EP+SI+CGHSFCQ CI      S +G+ G   CPVC+  +   NLRP
Sbjct: 11  EEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRP 70

Query: 66  NRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAM 125
           NR LAN+V  L+E+     +  +   CA HGE+L LFC++DGK +CW+C +S++HR H  
Sbjct: 71  NRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHT 130

Query: 126 VPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQ 185
             +EE AQEYQEK Q +L +L+ +++ AEKL   I  K+  WK  +E ++ RI  EF Q 
Sbjct: 131 FLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQL 190

Query: 186 KNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQ 245
           +N L   EQR+L++LE++E++ LRI+ E E  L  Q+Q+L+ELIS+L+RRC  S +ELLQ
Sbjct: 191 RNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQ 250

Query: 246 EVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCA---------VHITLDPDTA 296
           +V  V ERSE W L+  +    +LRS+   P LK+MLR C          V +TL+P TA
Sbjct: 251 DVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTLNPHTA 310

Query: 297 NPWLILSEDRRQVRLGDTQQSIPG-NEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWD 355
           N  L+L+++RRQVR    + S P   E+ +D    VLG+QHF SGKHYWEVDV  K AW 
Sbjct: 311 NLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDC--SVLGSQHFSSGKHYWEVDVAKKTAWI 368

Query: 356 LGVCRDSV-----------RRKGHFLLSSKSGFWTIWLWNKQKYEA--GTYPQTPLHLQV 402
           LGVC +S+               +     +SG+W I L +  +Y A   + P   L + V
Sbjct: 369 LGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTV 428

Query: 403 PPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSP 448
           PP +VG+FLDYEAG VSFYN+T+HG  IY+FS+  F   L P+F+P
Sbjct: 429 PPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP 474


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score =  400 bits (1029), Expect = e-111
 Identities = 215/466 (46%), Positives = 294/466 (63%), Gaps = 31/466 (6%)

Query: 12  EEVTCPICLDPFVEPVSIECGHSFCQECI------SQVGKGGGSVCPVCRQRFLLKNLRP 65
           EEVTCPICL+   EP+SI+CGHSFCQ CI      S +G+ G   CPVC+  +   NLRP
Sbjct: 39  EEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRP 98

Query: 66  NRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAM 125
           NR LAN+V  L+E+     +  +   CA HGE+L LFC++DGK +CW+C +S++HR H  
Sbjct: 99  NRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHT 158

Query: 126 VPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQ 185
             +EE AQEYQEK Q +L +L+ +++ AEKL   I  K+  WK  +E ++ RI  EF Q 
Sbjct: 159 FLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQL 218

Query: 186 KNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQ 245
           +N L   EQR+L++LE++E++ LRI+ E E  L  Q+Q+L+ELIS+L+RRC  S +ELLQ
Sbjct: 219 RNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQ 278

Query: 246 EVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCA---------VHITLDPDTA 296
           +V  V ERSE W L+  +    +LRS+   P LK+MLR C          V +TL+P TA
Sbjct: 279 DVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTLNPHTA 338

Query: 297 NPWLILSEDRRQVRLGDTQQSIPG-NEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWD 355
           N  L+L+++RRQVR    + S P   E+ +D    VLG+QHF SGKHYWEVDV  K AW 
Sbjct: 339 NLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDC--SVLGSQHFSSGKHYWEVDVAKKTAWI 396

Query: 356 LGVCRDSV-----------RRKGHFLLSSKSGFWTIWLWNKQKYEA--GTYPQTPLHLQV 402
           LGVC +S+               +     +SG+W I L +  +Y A   + P   L + V
Sbjct: 397 LGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTV 456

Query: 403 PPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSP 448
           PP +VG+FLDYEAG VSFYN+T+HG  IY+FS+  F   L P+F+P
Sbjct: 457 PPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYFNP 502


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  384 bits (986), Expect = e-106
 Identities = 209/468 (44%), Positives = 283/468 (60%), Gaps = 18/468 (3%)

Query: 12  EEVTCPICLDPFVEPVSIECGHSFCQECISQV------GKGGGSVCPVCRQRFLLKNLRP 65
           E+  CP+CLD   EPVS++CGHSFC  CIS+        +GG   CP CR  F     RP
Sbjct: 12  EDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFRPSGFRP 71

Query: 66  NRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAM 125
           NRQLA +V +++ +   A  G +  RCA HGE L  FCE+D  ALCWVC    +HR H  
Sbjct: 72  NRQLAGLVESVRRLGLGAGPGAR--RCARHGEDLSRFCEEDEAALCWVCDAGPEHRTHRT 129

Query: 126 VPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQ 185
            PL+EAA  YQ KLQ+AL  +R++ E A   E  +  K   WK+ VE Q+ R   EF + 
Sbjct: 130 APLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVEMQRQRFRLEFEKH 189

Query: 186 KNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQ 245
           + FL +EEQRQL+ LE +ER  L+ L E +++L QQS+AL+EL  EL  RC   AL LL+
Sbjct: 190 RGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQERCQRPALGLLE 249

Query: 246 EVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSED 305
            V  VL RS++    + +    EL++ C +PG +++LR   V + LDP TA+P L+L+ D
Sbjct: 250 GVRGVLSRSKAVTRLEAENIPMELKTACCIPGRRELLRKFQVDVKLDPATAHPSLLLTAD 309

Query: 306 RRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRR 365
            R V+ G+  + +P N ERFD++P +LG Q F SG+HYWEV V     W LGVC+D++ R
Sbjct: 310 LRSVQDGEPWRDVPNNPERFDTWPCILGLQSFSSGRHYWEVLVGEGAEWGLGVCQDTLPR 369

Query: 366 KGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTP-LHLQVPPCQVGIFLDYEAGMVSFYNIT 424
           KG    S ++G W +WL    +Y     P  P L L+ P C +GIFLDYEAG +SFYN+T
Sbjct: 370 KGETTPSPENGVWALWLLKGNEYMVLASPSVPLLQLESPRC-IGIFLDYEAGEISFYNVT 428

Query: 425 DHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGS 472
           D GS IY+F++  F+G LRP+F         +  PL L P  I   G+
Sbjct: 429 D-GSYIYTFNQ-LFSGLLRPYFFI------CDATPLILPPTTIAGSGN 468


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  377 bits (968), Expect = e-104
 Identities = 207/482 (42%), Positives = 292/482 (60%), Gaps = 16/482 (3%)

Query: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQV------GKGGGSVCPVC 54
           M   A +  + EEV CPIC+    EP+SI+CGHSFC  C+S +       +  G  CP+C
Sbjct: 1   MDPTALVEAIVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLC 60

Query: 55  RQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVC 114
           R     +NLRPN QLAN+V  ++ +      G +G+ C  HGE+L +FC++D   +C  C
Sbjct: 61  RAPVQPRNLRPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKLKMFCKEDVLIMCEAC 120

Query: 115 AQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQ 174
           +QS +H  H++VP+E+ A EY+ +L  AL  L+++QE A KLEV    + A WK  VET+
Sbjct: 121 SQSPEHEAHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETR 180

Query: 175 KSRIHAEFVQQKNFLVEEE--QRQL--------QELEKDEREQLRILGEKEAKLAQQSQA 224
           K  I  EF + +  L +++   RQL          L+++  E ++ L    ++L QQSQ 
Sbjct: 181 KQSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQV 240

Query: 225 LQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRT 284
           L  +I+EL  R       +LQ++  VL RS+SW+L+  +  S EL++ C V GL+++L+T
Sbjct: 241 LWRMIAELKERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCRVLGLREILKT 300

Query: 285 CAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYW 344
            A  + LDPDTA   LI+SEDR++V  GDT Q +P N ERF  Y +VLG+Q   SG+HYW
Sbjct: 301 YAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDNPERFYRYNIVLGSQCISSGRHYW 360

Query: 345 EVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPP 404
           EV+V  +  W LGVC+ +V RK    LS   GFW I L    +Y AGT     L L VPP
Sbjct: 361 EVEVGDRSEWGLGVCKQNVDRKEVVYLSPHYGFWVIRLRKGNEYRAGTDEYPILSLPVPP 420

Query: 405 CQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCP 464
            +VGIF+DYEA  +SFYN+TD GS I++F    F G L P+FSP ++ G  NTAPL +C 
Sbjct: 421 RRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPGRLLPYFSPCYSIGTNNTAPLAICS 480

Query: 465 LN 466
           L+
Sbjct: 481 LD 482


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  371 bits (953), Expect = e-103
 Identities = 213/500 (42%), Positives = 301/500 (60%), Gaps = 51/500 (10%)

Query: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGK------GGGSVCPVC 54
           MAS   L +  EEVTCPICL+   EP+S++CGHS C+ CI+   K      GG S CPVC
Sbjct: 1   MASKILLNVQ-EEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVC 59

Query: 55  RQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVC 114
              +  ++L+ N+ LAN+V  LKE+      G + + C  HGE+L LFC++D K +CW+C
Sbjct: 60  GISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLC 119

Query: 115 AQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQ 174
            +S++HR H  V  EE  +E QEKLQ  L  L++++E AEKLE +I  ++  WK  V+T+
Sbjct: 120 ERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTE 179

Query: 175 KSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDR 234
           + RI  EF Q ++ L  EEQR+LQ LE++E++ L    E E +L QQ Q ++ELIS+++ 
Sbjct: 180 RQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVEC 239

Query: 235 RCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKML---------RTC 285
           R   S +ELLQ++  +++ SE W LK   + S +L++V H P L +ML         R  
Sbjct: 240 RSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCY 299

Query: 286 AVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWE 345
            V +TL+    N  L+LSED+RQV       S+P    +  +Y  VLG+Q+F SGKHYWE
Sbjct: 300 WVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYG-VLGSQYFSSGKHYWE 352

Query: 346 VDVTGKEAWDLGV-CRDSVRRKGHFLLSSKS------------GFWTIWLWNKQKYEAGT 392
           VDV+ K AW LGV CR   R   + +    +            G+W I L NK KY  G 
Sbjct: 353 VDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKY--GV 410

Query: 393 YPQT--------PLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRP 444
           + ++         L + VPPC+VG+FLDYEAG+VSF+N+T HGSLIY FS+C F+ P+ P
Sbjct: 411 FEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYP 470

Query: 445 FFSPGFNDGGKNTAPLTLCP 464
           +F+P         AP+TLCP
Sbjct: 471 YFNP-----WNCPAPMTLCP 485


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  371 bits (953), Expect = e-103
 Identities = 213/500 (42%), Positives = 301/500 (60%), Gaps = 51/500 (10%)

Query: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGK------GGGSVCPVC 54
           MAS   L +  EEVTCPICL+   EP+S++CGHS C+ CI+   K      GG S CPVC
Sbjct: 1   MASKILLNVQ-EEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVC 59

Query: 55  RQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVC 114
              +  ++L+ N+ LAN+V  LKE+      G + + C  HGE+L LFC++D K +CW+C
Sbjct: 60  GISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLC 119

Query: 115 AQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQ 174
            +S++HR H  V  EE  +E QEKLQ  L  L++++E AEKLE +I  ++  WK  V+T+
Sbjct: 120 ERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTE 179

Query: 175 KSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDR 234
           + RI  EF Q ++ L  EEQR+LQ LE++E++ L    E E +L QQ Q ++ELIS+++ 
Sbjct: 180 RQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVEC 239

Query: 235 RCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKML---------RTC 285
           R   S +ELLQ++  +++ SE W LK   + S +L++V H P L +ML         R  
Sbjct: 240 RSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCY 299

Query: 286 AVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWE 345
            V +TL+    N  L+LSED+RQV       S+P    +  +Y  VLG+Q+F SGKHYWE
Sbjct: 300 WVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYG-VLGSQYFSSGKHYWE 352

Query: 346 VDVTGKEAWDLGV-CRDSVRRKGHFLLSSKS------------GFWTIWLWNKQKYEAGT 392
           VDV+ K AW LGV CR   R   + +    +            G+W I L NK KY  G 
Sbjct: 353 VDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKY--GV 410

Query: 393 YPQT--------PLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRP 444
           + ++         L + VPPC+VG+FLDYEAG+VSF+N+T HGSLIY FS+C F+ P+ P
Sbjct: 411 FEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYP 470

Query: 445 FFSPGFNDGGKNTAPLTLCP 464
           +F+P         AP+TLCP
Sbjct: 471 YFNP-----WNCPAPMTLCP 485


>gi|51477690 tripartite motif-containing 6 and tripartite
           motif-containing 34 [Homo sapiens]
          Length = 842

 Score =  371 bits (953), Expect = e-103
 Identities = 213/500 (42%), Positives = 301/500 (60%), Gaps = 51/500 (10%)

Query: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGK------GGGSVCPVC 54
           MAS   L +  EEVTCPICL+   EP+S++CGHS C+ CI+   K      GG S CPVC
Sbjct: 355 MASKILLNVQ-EEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVC 413

Query: 55  RQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVC 114
              +  ++L+ N+ LAN+V  LKE+      G + + C  HGE+L LFC++D K +CW+C
Sbjct: 414 GISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLC 473

Query: 115 AQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQ 174
            +S++HR H  V  EE  +E QEKLQ  L  L++++E AEKLE +I  ++  WK  V+T+
Sbjct: 474 ERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTE 533

Query: 175 KSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDR 234
           + RI  EF Q ++ L  EEQR+LQ LE++E++ L    E E +L QQ Q ++ELIS+++ 
Sbjct: 534 RQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVEC 593

Query: 235 RCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKML---------RTC 285
           R   S +ELLQ++  +++ SE W LK   + S +L++V H P L +ML         R  
Sbjct: 594 RSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCY 653

Query: 286 AVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWE 345
            V +TL+    N  L+LSED+RQV       S+P    +  +Y  VLG+Q+F SGKHYWE
Sbjct: 654 WVDVTLNSVNLNLNLVLSEDQRQV------ISVPIWPFQCYNYG-VLGSQYFSSGKHYWE 706

Query: 346 VDVTGKEAWDLGV-CRDSVRRKGHFLLSSKS------------GFWTIWLWNKQKYEAGT 392
           VDV+ K AW LGV CR   R   + +    +            G+W I L NK KY  G 
Sbjct: 707 VDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKY--GV 764

Query: 393 YPQT--------PLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRP 444
           + ++         L + VPPC+VG+FLDYEAG+VSF+N+T HGSLIY FS+C F+ P+ P
Sbjct: 765 FEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYP 824

Query: 445 FFSPGFNDGGKNTAPLTLCP 464
           +F+P         AP+TLCP
Sbjct: 825 YFNP-----WNCPAPMTLCP 839



 Score =  272 bits (695), Expect = 6e-73
 Identities = 135/280 (48%), Positives = 187/280 (66%), Gaps = 6/280 (2%)

Query: 12  EEVTCPICLDPFVEPVSIECGHSFCQECI------SQVGKGGGSVCPVCRQRFLLKNLRP 65
           EEVTCPICL+   EP+SI+CGHSFCQ CI      S +G+ G   CPVC+  +   NLRP
Sbjct: 39  EEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNLRP 98

Query: 66  NRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAM 125
           NR LAN+V  L+E+     +  +   CA HGE+L LFC++DGK +CW+C +S++HR H  
Sbjct: 99  NRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGHHT 158

Query: 126 VPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQ 185
             +EE AQEYQEK Q +L +L+ +++ AEKL   I  K+  WK  +E ++ RI  EF Q 
Sbjct: 159 FLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQL 218

Query: 186 KNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQ 245
           +N L   EQR+L++LE++E++ LRI+ E E  L  Q+Q+L+ELIS+L+RRC  S +ELLQ
Sbjct: 219 RNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTMELLQ 278

Query: 246 EVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTC 285
           +V  V ERSE W L+  +    +LRS+   P LK+MLR C
Sbjct: 279 DVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVC 318


>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
          Length = 498

 Score =  357 bits (916), Expect = 1e-98
 Identities = 203/491 (41%), Positives = 286/491 (58%), Gaps = 44/491 (8%)

Query: 12  EEVTCPICLDPFVEPVSIECGHSFCQECI------SQVGKGGGSVCPVCRQRFLLKNLRP 65
           +EVTCPICL+   EP+S++CGHSFCQ CI      S +   G S CPVC+ RF   NLRP
Sbjct: 11  KEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNLRP 70

Query: 66  NRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAM 125
           NR LAN+V  +KE+    +EG + + C  HG++L +FC++DGK +CWVC  S++H+ H  
Sbjct: 71  NRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCELSQEHQGHQT 130

Query: 126 VPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQ 185
             + E  +E QEKLQVAL  L ++ + AEKLE +I  +R  WK  ++ ++ +I   F + 
Sbjct: 131 FRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQKILKGFNEM 190

Query: 186 KNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQ 245
           +  L  EEQR+LQ+LE+ E   L  L     +L QQ Q    LIS+L RR   S++E+LQ
Sbjct: 191 RVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRLRGSSVEMLQ 250

Query: 246 EVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCA---------VHITLDPDTA 296
           +VI V++RSESW LK     S +L+SV  VP L  ML+            V + L+P +A
Sbjct: 251 DVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYWVDVMLNPGSA 310

Query: 297 NPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDL 356
              + +S D+RQV+   T      N   F ++  V G Q+F SGK+YWEVDV+GK AW L
Sbjct: 311 TSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFG-VFGCQYFSSGKYYWEVDVSGKIAWIL 369

Query: 357 GVCRD----SVRRKGHFLLS-------------SKSGFWTIWLWNKQKYEA-----GTYP 394
           GV       + R+   F                 + G+W I L N  +Y A      + P
Sbjct: 370 GVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNAFEDSSSSDP 429

Query: 395 QT-PLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDG 453
           +   L + VPPC++G+FLDYEAG+VSF+N+T+HG+LIY FS C F+ P  P+F+P     
Sbjct: 430 KVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYPYFNP----- 484

Query: 454 GKNTAPLTLCP 464
                P+T+CP
Sbjct: 485 WNCLVPMTVCP 495


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  357 bits (915), Expect = 2e-98
 Identities = 197/473 (41%), Positives = 288/473 (60%), Gaps = 14/473 (2%)

Query: 2   ASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKG--GGSVCPVCRQRFL 59
           ++AA L  +  E +C +CL+   EPV IECGH+FC+ CI++  +       CPVCR+   
Sbjct: 15  STAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSR 74

Query: 60  LKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRK 119
            ++LRPNRQL +MV   K++    R+      C  H E L LFC +D +A+C +CA S  
Sbjct: 75  YRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHT 134

Query: 120 HRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIH 179
           HR H +VPL++A QEY+EKLQ  L  L +K +   + +     K  + K+ VE+++ +I 
Sbjct: 135 HRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQIL 194

Query: 180 AEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSS 239
            EF +    L EE+Q  L  LE++E++ L+ L E  A L  + + L  L +E++ +C  S
Sbjct: 195 REFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQS 254

Query: 240 ALELLQEVIIVLERSESWNLKDLDITSPEL---RSVCHVP----GLKKMLRTCAVHITLD 292
             E+L++V   LE+ E   +K +++TS  +   ++  + P     L+K+L+     +TLD
Sbjct: 255 GFEMLKDVKSTLEKCE--KVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLD 312

Query: 293 PDTANPWLILSEDRRQVRLGDTQ-QSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGK 351
           P+TA+P L+LSEDR+ V+  +T+ + +P    RF  YP VL  + F SG+HYWEV+V  K
Sbjct: 313 PETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDK 372

Query: 352 EAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFL 411
             W +GVCRDSV RKG      ++G+W + LWN  KY A T P TPLH++V P +VGIFL
Sbjct: 373 THWAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFL 432

Query: 412 DYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCP 464
           DYEAG +SFYN+TD  S IY+F++  FT  L P F PG   G KN APLT+ P
Sbjct: 433 DYEAGTLSFYNVTDR-SHIYTFTD-TFTEKLWPLFYPGIRAGRKNAAPLTIRP 483


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  352 bits (904), Expect = 3e-97
 Identities = 205/471 (43%), Positives = 281/471 (59%), Gaps = 12/471 (2%)

Query: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVG--KGGGSVCPVCRQRF 58
           MA+    T + EE TC ICLD F +PV  +CGH+FC+ECI +      G   CP CR+  
Sbjct: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELS 60

Query: 59  LLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSR 118
             +NLRPNR LA M    + +   +    QG  C  H E L  FC  + + LC  C +S 
Sbjct: 61  PQRNLRPNRPLAKMAEMARRLHPPSPV-PQGV-CPAHREPLAAFCGDELRLLCAACERSG 118

Query: 119 KHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRI 178
           +H  H + PL++AA++ + KL+ +L  LR++ + A   + +       W+K VE+Q+  +
Sbjct: 119 EHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNV 178

Query: 179 HAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHS 238
             EF + +  L EEEQ+ LQ LE++E E L  L E  A L QQS  L ELI+EL+ RC  
Sbjct: 179 LGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQL 238

Query: 239 SALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANP 298
            AL LLQ++   L R +   L+  ++   ELR+VC VPGL + LR     +TLDPDTANP
Sbjct: 239 PALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDTANP 298

Query: 299 WLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGV 358
            LILSEDRR V+ GD +Q++P + ERFD  P VLG + F SG+HYWEV+V  + +W LGV
Sbjct: 299 ELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGV 358

Query: 359 CRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMV 418
           CR++V RK    LS+ +GFW I ++    Y +      P  L+ PP +VGIFLDYEAG +
Sbjct: 359 CRENVNRKEKGELSAGNGFW-ILVFLGSYYNSSERALAP--LRDPPRRVGIFLDYEAGHL 415

Query: 419 SFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGS 469
           SFY+ TD GSL++ F E  F+G LRP FSP       +  P+T+C    GS
Sbjct: 416 SFYSATD-GSLLFIFPEIPFSGTLRPLFSP----LSSSPTPMTICRPKGGS 461


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score =  350 bits (898), Expect = 2e-96
 Identities = 194/458 (42%), Positives = 272/458 (59%), Gaps = 20/458 (4%)

Query: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGS--------VCP 52
           MAS      M EE TC ICL     PVSI CGHS+C  CI+   K             CP
Sbjct: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60

Query: 53  VCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCW 112
            CR  F + +LRPN+QL +++  LKE  QE         C  HGE+ HLFCE +G+ +CW
Sbjct: 61  QCRAPFHMDSLRPNKQLGSLIEALKETDQEMS-------CEEHGEQFHLFCEDEGQLICW 113

Query: 113 VCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVE 172
            C ++ +H+ H    +E+  Q Y+EKLQ A+ +L++ ++   + ++  A++   WK+ V+
Sbjct: 114 RCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQ 173

Query: 173 TQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISEL 232
            Q+ +I ++F   + FL EEE+  L  LEK+E++ L  L + EA L  +S  L+  I EL
Sbjct: 174 IQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILEL 233

Query: 233 DRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGL----KKMLRTCAVH 288
           + +C  SA +LLQ V   L RS +  L+  +  S EL ++C+V  L    KKMLR+  V 
Sbjct: 234 EEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSHQVS 293

Query: 289 ITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDV 348
           +TLDPDTA+  LILSEDRRQV  G TQ++   +  RF ++P VLG + F SG+ Y+EVDV
Sbjct: 294 VTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDV 353

Query: 349 TGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVG 408
                WDLGVC ++V+R        +SGFWT+ L  K+ Y A T P T LHL   P  VG
Sbjct: 354 GEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVG 413

Query: 409 IFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFF 446
           IFLDYEAG+VSFYN  + G  I++F + +F+  LRP+F
Sbjct: 414 IFLDYEAGVVSFYN-GNTGCHIFTFPKASFSDTLRPYF 450


>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
           sapiens]
          Length = 493

 Score =  348 bits (894), Expect = 5e-96
 Identities = 199/488 (40%), Positives = 287/488 (58%), Gaps = 45/488 (9%)

Query: 12  EEVTCPICLDPFVEPVSIECGHSFCQECISQVGKG-----GGSVCPVCRQRFLLKNLRPN 66
           EEVTCPICL+   +P+S++CGHSFCQ C++   K      G S CPVCR  +  +N+RPN
Sbjct: 11  EEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENIRPN 70

Query: 67  RQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMV 126
           R +AN+V  L+E+     EG + + CA HGE+L LFC++DGK +CW+C +S++HR H   
Sbjct: 71  RHVANLVEKLREVKLSP-EGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQEHRGHHTF 129

Query: 127 PLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQK 186
           P EE AQEYQ KLQ AL  LR+KQ+ AE+LE +I  ++A WK  ++  K+ + A+F Q +
Sbjct: 130 PTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVLADFEQLR 189

Query: 187 NFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQE 246
           + L  EE  +LQ LEK+E + L+ L   E ++ QQ+Q+L+ELIS+L+ R   S +ELLQ 
Sbjct: 190 DILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGSVMELLQG 249

Query: 247 VIIVLERSESWNLKDLDITSPELRSVCHVPGLKKML---------RTCAVHITLDPDTAN 297
           V  V++R+E+  LK  +      R V   P LK ML         R   V +T+ P+  +
Sbjct: 250 VDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWVDVTVAPNNIS 309

Query: 298 PWLILSEDRRQVRLGDTQQSIPGNEERFDSY------PMVLGAQHFHSGKHYWEVDVTGK 351
              ++SED+RQV     Q        R+ ++        +LG+Q   SGKHYWEVDV+ K
Sbjct: 310 -CAVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKHYWEVDVSKK 368

Query: 352 EAWDLGVCRD-------SVRRKGHFLLSSKSGFWTIWL--------WNKQKYEAGTYP-Q 395
            AW LGVC         ++ +  ++    K G+W I L        +    +   + P  
Sbjct: 369 TAWILGVCAGFQPDAMCNIEKNENY--QPKYGYWVIGLEEGVKCSAFQDSSFHTPSVPFI 426

Query: 396 TPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGK 455
            PL + + P +VG+FLDYEA  VSF+NIT+HG LIY FS C+F+ P+ P+ +P      K
Sbjct: 427 VPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPYLNP-----RK 481

Query: 456 NTAPLTLC 463
              P+TLC
Sbjct: 482 CGVPMTLC 489


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  344 bits (882), Expect = 1e-94
 Identities = 196/501 (39%), Positives = 288/501 (57%), Gaps = 40/501 (7%)

Query: 2   ASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKG--GGSVCPVCRQRFL 59
           ++AA L  +  E +C +CL+   EPV IECGH+FC+ CI++  +       CPVCR+   
Sbjct: 15  STAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSR 74

Query: 60  LKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRK 119
            ++LRPNRQL +MV   K++    R+      C  H E L LFC +D +A+C +CA S  
Sbjct: 75  YRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHT 134

Query: 120 HRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIH 179
           HR H +VPL++A QEY+EKLQ  L  L +K +   + +     K  + K+ VE+++ +I 
Sbjct: 135 HRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQIL 194

Query: 180 AEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSS 239
            EF +    L EE+Q  L  LE++E++ L+ L E  A L  + + L  L +E++ +C  S
Sbjct: 195 REFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQS 254

Query: 240 ALELLQEVIIVLERS----------------------------ESWNLKDLDITSPEL-- 269
             E+L++V   LE++                                +K +++TS  +  
Sbjct: 255 GFEMLKDVKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINRCEKVKTMEVTSVSIEL 314

Query: 270 -RSVCHVP----GLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQ-QSIPGNEE 323
            ++  + P     L+K+L+     +TLDP+TA+P L+LSEDR+ V+  +T+ + +P    
Sbjct: 315 EKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPR 374

Query: 324 RFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLW 383
           RF  YP VL  + F SG+HYWEV+V  K  W +GVCRDSV RKG      ++G+W + LW
Sbjct: 375 RFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLPETGYWRVRLW 434

Query: 384 NKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLR 443
           N  KY A T P TPLH++V P +VGIFLDYEAG +SFYN+TD  S IY+F++  FT  L 
Sbjct: 435 NGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDR-SHIYTFTD-TFTEKLW 492

Query: 444 PFFSPGFNDGGKNTAPLTLCP 464
           P F PG   G KN APLT+ P
Sbjct: 493 PLFYPGIRAGRKNAAPLTIRP 513


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  332 bits (851), Expect = 5e-91
 Identities = 186/495 (37%), Positives = 282/495 (56%), Gaps = 31/495 (6%)

Query: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQV-GKGGGSV-CPVCRQRF 58
           MAS +    + +E TCP+CL  F EP+ ++CGH+ C  C+++  G    +V CP CR+ F
Sbjct: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETF 60

Query: 59  LLKNLRPNRQLANMVNNLKEISQEAREGTQGER--CAVHGERLHLFCEKDGKALCWVCAQ 116
             +++RPNR LAN+   +K++  E   G  GE   C  H E L L+CE+D   +C VC +
Sbjct: 61  PQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDR 120

Query: 117 SRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKS 176
           SR+HR H+++PLEEA + ++E++Q  L  L+R ++L ++   +    RA+     + ++ 
Sbjct: 121 SREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMERE 180

Query: 177 RIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRC 236
           +I  EF Q  + L E E R L  LE+ +      +     + +     L  LI++L+ + 
Sbjct: 181 KIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQ 240

Query: 237 HSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRT------------ 284
                ELLQ++   L R+E   + +  IT P+L+   H+   K +  T            
Sbjct: 241 QQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQS 300

Query: 285 -------------CAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMV 331
                         +V +TLDPDTA P LILS++ RQVR    QQ +P N ERF+ +P V
Sbjct: 301 DMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCV 360

Query: 332 LGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAG 391
           LG+  F +G+HYWEV+V  K  W +GVC DSV RKG    + ++GFW + LW  ++Y A 
Sbjct: 361 LGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWAL 420

Query: 392 TYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFN 451
           T P T L L+ P  +VGIFLDY+AG VSFYN+T+     ++FS   F GP+RP+FS  ++
Sbjct: 421 TSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTER-CHTFTFSHATFCGPVRPYFSLSYS 479

Query: 452 DGGKNTAPLTLCPLN 466
            GGK+ APL +CP++
Sbjct: 480 -GGKSAAPLIICPMS 493


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  296 bits (757), Expect = 4e-80
 Identities = 174/459 (37%), Positives = 259/459 (56%), Gaps = 20/459 (4%)

Query: 12  EEVTCPICLDPFVEPVSIECGHSFCQECIS---QVGKG--------GGSVCPVCRQRFLL 60
           EE TC ICLD F +PV   CGH+FC+ CI    +  +G        G   CP CR+    
Sbjct: 12  EEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQ 71

Query: 61  KNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKH 120
           +NL PNR L  +     E++Q+     + + C  H E L LFC+KD   +C VC +SR+H
Sbjct: 72  RNLLPNRLLTKVA----EMAQQHPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREH 127

Query: 121 RDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHA 180
           R H ++P EEA Q Y+ KL+  +  LR +      L+       A+W+  V+ ++ RI  
Sbjct: 128 RLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVL 187

Query: 181 EFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSA 240
           EF +   +LVEEEQR LQ LE +E E    L E  A L +Q  +L+ L+ +L+ R     
Sbjct: 188 EFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQGP 247

Query: 241 LELLQEVIIVLERSESWNLKDLDITSP-ELRSVCHVPGLKKMLRTCAVHITLDPDTANPW 299
           L++LQ++   L R  + +++  ++  P   R+VC VPG  ++LR     +  D  +A P+
Sbjct: 248 LQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVVPDATSAYPY 307

Query: 300 LILSEDRRQVRLGDTQQ-SIPGNEERFDSYPMVLGAQHFHSGKHYWEV--DVTGKEAWDL 356
           L+L E R++  LG + + S   +++RF +YP  +G   F SG+HYWEV  ++TG   W L
Sbjct: 308 LLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWAL 367

Query: 357 GVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAG 416
           GVCRD+V RK       ++GFW + L    KY +     TP+ L  PP  +GIFLD+EAG
Sbjct: 368 GVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIFLDFEAG 427

Query: 417 MVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGK 455
            VSFY+++D GS ++++S+  F GPL+PFF  G    G+
Sbjct: 428 EVSFYSVSD-GSHLHTYSQATFPGPLQPFFCLGAPKSGQ 465


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  296 bits (757), Expect = 4e-80
 Identities = 174/459 (37%), Positives = 259/459 (56%), Gaps = 20/459 (4%)

Query: 12  EEVTCPICLDPFVEPVSIECGHSFCQECIS---QVGKG--------GGSVCPVCRQRFLL 60
           EE TC ICLD F +PV   CGH+FC+ CI    +  +G        G   CP CR+    
Sbjct: 12  EEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQ 71

Query: 61  KNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKH 120
           +NL PNR L  +     E++Q+     + + C  H E L LFC+KD   +C VC +SR+H
Sbjct: 72  RNLLPNRLLTKVA----EMAQQHPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREH 127

Query: 121 RDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHA 180
           R H ++P EEA Q Y+ KL+  +  LR +      L+       A+W+  V+ ++ RI  
Sbjct: 128 RLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVL 187

Query: 181 EFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSA 240
           EF +   +LVEEEQR LQ LE +E E    L E  A L +Q  +L+ L+ +L+ R     
Sbjct: 188 EFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQGP 247

Query: 241 LELLQEVIIVLERSESWNLKDLDITSP-ELRSVCHVPGLKKMLRTCAVHITLDPDTANPW 299
           L++LQ++   L R  + +++  ++  P   R+VC VPG  ++LR     +  D  +A P+
Sbjct: 248 LQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVVPDATSAYPY 307

Query: 300 LILSEDRRQVRLGDTQQ-SIPGNEERFDSYPMVLGAQHFHSGKHYWEV--DVTGKEAWDL 356
           L+L E R++  LG + + S   +++RF +YP  +G   F SG+HYWEV  ++TG   W L
Sbjct: 308 LLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWAL 367

Query: 357 GVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAG 416
           GVCRD+V RK       ++GFW + L    KY +     TP+ L  PP  +GIFLD+EAG
Sbjct: 368 GVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIFLDFEAG 427

Query: 417 MVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGK 455
            VSFY+++D GS ++++S+  F GPL+PFF  G    G+
Sbjct: 428 EVSFYSVSD-GSHLHTYSQATFPGPLQPFFCLGAPKSGQ 465


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score =  295 bits (754), Expect = 8e-80
 Identities = 180/471 (38%), Positives = 270/471 (57%), Gaps = 11/471 (2%)

Query: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSV--CPVCRQRF 58
           M++A  +  + EE+TC ICLD F  PV+ ECGHSFC  C+ +  +   +   CP C +  
Sbjct: 1   MSTADLMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNTPLSCPECWRTL 60

Query: 59  LLKNLRPNRQLANMVNNLKEISQEA--REGTQGERCAVHGERLHLFCEKDGKALCWVCAQ 116
              + + N +L  + +  +++  +    E  QG    +      L  ++ G +  +V   
Sbjct: 61  EGPHFQSNERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGS-AFVAQS 119

Query: 117 SRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKS 176
              +R H      EA + ++EKLQ  L  LR +++ A+ +      +    ++  +T K 
Sbjct: 120 HGANRVHLS---SEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKTCKQ 176

Query: 177 RIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRC 236
            + +E+++   FL EEEQ QLQ LE++E+E +R L   E KL QQ ++L ++I++++   
Sbjct: 177 VVVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIESSS 236

Query: 237 HSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTA 296
            SSA E L+EV   LERSE   L+  + T+ EL S+C + G+K+MLR  +  ITLDP TA
Sbjct: 237 QSSAFESLEEVRGALERSEPLLLQCPEATTTEL-SLCRITGMKEMLRKFSTEITLDPATA 295

Query: 297 NPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDL 356
           N +L+LSED + V+ G ++Q +P N ERFD    VLG Q F SG+HYWEV+V  K  W++
Sbjct: 296 NAYLVLSEDLKSVKYGGSRQQLPDNPERFDQSATVLGTQIFTSGRHYWEVEVGNKTEWEV 355

Query: 357 GVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAG-TYPQTPLHLQVPPCQVGIFLDYEA 415
           G+C+DSV RKG+        F  I L     Y    + P    H++ P C+VG+FLDYE+
Sbjct: 356 GICKDSVSRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVCKVGVFLDYES 415

Query: 416 GMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLN 466
           G ++FYN TD  SLIYSF + +F   LRP FSP   + G NT PLT+C LN
Sbjct: 416 GHIAFYNGTDE-SLIYSFPQASFQEALRPIFSPCLPNEGTNTDPLTICSLN 465


>gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]
          Length = 450

 Score =  273 bits (698), Expect = 2e-73
 Identities = 163/440 (37%), Positives = 247/440 (56%), Gaps = 20/440 (4%)

Query: 31  CGHSFCQECIS---QVGKG--------GGSVCPVCRQRFLLKNLRPNRQLANMVNNLKEI 79
           CGH+FC+ CI    +  +G        G   CP CR+    +NL PNR L  +     E+
Sbjct: 4   CGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQRNLLPNRLLTKVA----EM 59

Query: 80  SQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKL 139
           +Q+     + + C  H E L LFC+KD   +C VC +SR+HR H ++P EEA Q Y+ KL
Sbjct: 60  AQQHPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQGYKLKL 119

Query: 140 QVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQE 199
           +  +  LR +      L+       A+W+  V+ ++ RI  EF +   +LVEEEQR LQ 
Sbjct: 120 EEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQA 179

Query: 200 LEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNL 259
           LE +E E    L E  A L +Q  +L+ L+ +L+ R     L++LQ++   L R  + ++
Sbjct: 180 LETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSV 239

Query: 260 KDLDITSP-ELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQ-S 317
           +  ++  P   R+VC VPG  ++LR     +  D  +A P+L+L E R++  LG + + S
Sbjct: 240 QCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVVPDATSAYPYLLLYESRQRRYLGSSPEGS 299

Query: 318 IPGNEERFDSYPMVLGAQHFHSGKHYWEV--DVTGKEAWDLGVCRDSVRRKGHFLLSSKS 375
              +++RF +YP  +G   F SG+HYWEV  ++TG   W LGVCRD+V RK       ++
Sbjct: 300 GFCSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDNVSRKDRVPKCPEN 359

Query: 376 GFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSE 435
           GFW + L    KY +     TP+ L  PP  +GIFLD+EAG VSFY+++D GS ++++S+
Sbjct: 360 GFWVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSD-GSHLHTYSQ 418

Query: 436 CAFTGPLRPFFSPGFNDGGK 455
             F GPL+PFF  G    G+
Sbjct: 419 ATFPGPLQPFFCLGAPKSGQ 438


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score =  270 bits (689), Expect = 3e-72
 Identities = 168/481 (34%), Positives = 259/481 (53%), Gaps = 29/481 (6%)

Query: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSV--CPVCRQRF 58
           M     L  + EE +CPICL+   +PV+I CGH+FC+ C+S   K       CPVCR  F
Sbjct: 1   MEFVTALVNLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDDTFPCPVCRFCF 60

Query: 59  LLKNLRPNRQLANMVNNLKEIS---QEAREGTQGERCAVHGERLHLFCEKDGKALCWVCA 115
             K+ R N QL N+    K++     + +   +   C  H + L LFC KD + LC  C+
Sbjct: 61  PYKSFRRNPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCS 120

Query: 116 QSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQK 175
            S KH+ H + P+++AA  ++E L+ +L  LR   E  EK+ +    K  + KK VE ++
Sbjct: 121 FSTKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKR 180

Query: 176 SRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRR 235
             I++EF Q + FL  E++  L++++ +E   L  L E   +L+     L+ L+ E++ +
Sbjct: 181 EEINSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGK 240

Query: 236 CHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVC----------HVPGLKKMLRTC 285
              S LELL +       ++S + K  ++  PEL S               GL ++++  
Sbjct: 241 SVQSNLELLTQ-------AKSMHHKYQNLKCPELFSFRLTKYGFSLPPQYSGLDRIIKPF 293

Query: 286 AVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWE 345
            V + LD +TA+P L++SEDR+ VR    +++I  +  RF   P VLG+Q F SG+HYWE
Sbjct: 294 QVDVILDLNTAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQRFSSGRHYWE 353

Query: 346 VDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPC 405
           V+V  K  W LGVC+D + R      S   GFW I  + K  Y A     T L   V P 
Sbjct: 354 VEVGNKPKWILGVCQDCLLRNWQDQPSVLGGFWAIGRYMKSGYVASGPKTTQLLPVVKPS 413

Query: 406 QVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPL 465
           ++GIFLDYE G +SFYN+ D  S++Y+F++C FT  + P+F       G ++ PL +C +
Sbjct: 414 KIGIFLDYELGDLSFYNMNDR-SILYTFNDC-FTEAVWPYFYT-----GTDSEPLKICSV 466

Query: 466 N 466
           +
Sbjct: 467 S 467


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score =  269 bits (688), Expect = 4e-72
 Identities = 166/473 (35%), Positives = 256/473 (54%), Gaps = 21/473 (4%)

Query: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSV--CPVCRQRF 58
           MA AA LT +  E  C ICLD   +PV+IECGH+FC+ CI Q       +  CPVCR + 
Sbjct: 1   MAVAAALTGLQAEAKCSICLDYLSDPVTIECGHNFCRSCIQQSWLDLQELFPCPVCRHQC 60

Query: 59  LLKNLRPNRQLANMVNN---LKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCA 115
              + R N QL  M+     L+      R+  +   C  H + L +FC++D   LC +C 
Sbjct: 61  QEGHFRSNTQLGRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMVLCPLCT 120

Query: 116 QSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQK 175
           Q   H+ H + P+E+AA  Y+++    +  L+++    +KL    + K  + ++ VE Q+
Sbjct: 121 QPPDHQGHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREMVENQR 180

Query: 176 SRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRR 235
             + +EF     FL  E+Q  L  L ++E++  + L       +  S  L+  +S++   
Sbjct: 181 QELSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKVVEL 240

Query: 236 CHSSALELLQEVIIVLERSESWNLKDLDITSPEL-RSVCHVP----GLKKMLRTCAVHIT 290
              S LELL ++ I  E   S N     I S  L R  C  P     L+++++   V I 
Sbjct: 241 SELSELELLSQIKIFYE---SENESSPSIFSIHLKRDGCSFPPQYSALQRIIKKFKVEII 297

Query: 291 LDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTG 350
           LDP+TA+P LI+SED+++VR    +Q +PG  +RF   P+VLG  +FHSG+H+WE++V  
Sbjct: 298 LDPETAHPNLIVSEDKKRVRFTKRKQKVPGFPKRFTVKPVVLGFPYFHSGRHFWEIEVGD 357

Query: 351 KEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIF 410
           K  W +G+C+DS+  K     S++   W I L +   +  G +P TPL L+V    +GIF
Sbjct: 358 KSEWAIGICKDSLPTKARRPSSAQQECWRIELQDDGYHAPGAFP-TPLLLEVKARAIGIF 416

Query: 411 LDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLC 463
           LDYE G +SFYN+ +  S I +F++  FTGPLRP+F       G ++ PL +C
Sbjct: 417 LDYEMGEISFYNMAEK-SHICTFTD-TFTGPLRPYFYV-----GPDSQPLRIC 462


>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
           sapiens]
          Length = 474

 Score =  261 bits (668), Expect = 7e-70
 Identities = 173/459 (37%), Positives = 245/459 (53%), Gaps = 33/459 (7%)

Query: 12  EEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSV--CPVCRQRFLLKNLRPNRQL 69
           EE+TCPICLD F +PVSIECGH+FC+ C+ +    GG    CP CR       LRPN  L
Sbjct: 8   EELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNWAL 67

Query: 70  ANMVNNLKEISQEAREG-TQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPL 128
           A     L E +Q  R G      C  H E L LFCE D + +C VC +S++H+ HAM P+
Sbjct: 68  AR----LTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPI 123

Query: 129 EEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRA-DWKKTVETQKSRIHAEFVQQKN 187
           +EA + Y+EKL  +   L  K +    L+ ++ +K A  WK  +++Q+ RI  EF +  N
Sbjct: 124 DEAFESYREKLLKSQRNLVAKMKKVMHLQ-DVEVKNATQWKDKIKSQRMRISTEFSKLHN 182

Query: 188 FLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEV 247
           FLVEEE   LQ L K+E E  + L E   KL Q   +L++LI E+  +  +  LELLQ  
Sbjct: 183 FLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNP 242

Query: 248 IIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRR 307
             VL RSE  ++ +  + + ++++VC +P +K+ML+   V + L  DTA+P L+ S++ R
Sbjct: 243 KEVLTRSEIQDV-NYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGR 301

Query: 308 QVRLGDTQQSIP------------------GNEERFDSYPMVLGAQHFHSGKHYWEVDVT 349
            V+   +  S P                     ERF   P VLG   F SGKHYWEV+  
Sbjct: 302 YVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESR 361

Query: 350 GKEAWDLGVCRDSVRR-KGHFLLSSKSGFWTIWLWNKQKY-EAGTYPQTPLHLQVPPCQV 407
                 +GVCR+ V        +S   G W I+ W+   Y     +P TP   +    +V
Sbjct: 362 DSLEVAVGVCREDVMGITDRSKMSPDVGIWAIY-WSAAGYWPLIGFPGTPTQQEPALHRV 420

Query: 408 GIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFF 446
           G++LD   G VSFY+  D G  +++FS C+    LRPFF
Sbjct: 421 GVYLDRGTGNVSFYSAVD-GVHLHTFS-CSSVSRLRPFF 457


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score =  257 bits (656), Expect = 2e-68
 Identities = 180/481 (37%), Positives = 248/481 (51%), Gaps = 53/481 (11%)

Query: 13  EVTCPICLDPFVEPVSIECGHSFCQECISQVGK--GGGSV------------CPVCRQRF 58
           E TC ICL+ F EPVS+ECGHSFC+ CI +  +  G GSV            CP CR+  
Sbjct: 26  EATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCREPA 85

Query: 59  LLKNLRPNRQLANMVNNLKEIS-----------QEAREGTQGERCAVHGERLHLFCEKDG 107
               LRPNRQLA +   L+  S           Q A       RC  HGE   L+C+ DG
Sbjct: 86  RPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYCQDDG 145

Query: 108 KALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADW 167
           +A+C VC ++R+HR+HA++PL+EA QE +E L+  L  L+++ E  E        +  + 
Sbjct: 146 RAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKESKEL 205

Query: 168 KKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQE 227
            K +  ++ ++ AEF   + FLVE+E R L  LE+  RE  +   E  A+L  +   L +
Sbjct: 206 LKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSK 265

Query: 228 LISELDRRCHSSALELLQEVIIVLER-SESWNLKDLDITSPELRSVCHVP----GLKKML 282
           L S++        L+ LQE    L R S     K   ++S     V +V      LK ML
Sbjct: 266 LSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGML 325

Query: 283 RTC------------AVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPM 330
           +               V +TLDPDTANP LILS D + VRLG+  Q +P +  RFD+   
Sbjct: 326 KKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTR 385

Query: 331 VLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEA 390
           VL +  F SG+H+WEV+V  K+ W  GV R+SVRRKG    + + G W + L N  +Y A
Sbjct: 386 VLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQL-NGGQYWA 444

Query: 391 GTYPQ-TPL---HLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFF 446
            T P+ +PL   HL     +V + LD E G VSFY + D   L Y+F    F   + P F
Sbjct: 445 VTSPERSPLSCGHLS----RVRVALDLEVGAVSFYAVEDMRHL-YTF-RVNFQERVFPLF 498

Query: 447 S 447
           S
Sbjct: 499 S 499


>gi|4557743 Mediterranean fever protein [Homo sapiens]
          Length = 781

 Score =  253 bits (646), Expect = 3e-67
 Identities = 146/409 (35%), Positives = 230/409 (56%), Gaps = 31/409 (7%)

Query: 91  RCAVHGERLHL-FCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRK 149
           +C  H +++ L FCE   + +C +C+ S++H+ H + P+EE A E+++K+Q  L  L++ 
Sbjct: 374 QCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKL 433

Query: 150 QELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLR 209
           ++  E+       K   + K  E  K R+  +  Q   FL ++E   +  LE   +   +
Sbjct: 434 RKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQ 493

Query: 210 ILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERS------ESWNL---- 259
           I    + +++Q    L  LI EL+ +   S  ELLQ++  +L R+      E W      
Sbjct: 494 IRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVPEKWTTPQEI 553

Query: 260 ---------------KDLDITSPELRSVCHVPGLKKML--RTCAVHITLDPDTANPWLIL 302
                          K     S  LRS   +  + +++  +  AV++ LD +TA P LI 
Sbjct: 554 KQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIF 613

Query: 303 SEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDS 362
           S+D + VRLG+  + +P   +RFDS  +VLG+  F SG+ YWEV+V  K AW LG C+ S
Sbjct: 614 SDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTS 673

Query: 363 VRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYN 422
           + RKG+  LS ++G+W + +  + +Y+A + P T L ++ PP +VGIF+DY  G +SFYN
Sbjct: 674 ISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYN 733

Query: 423 ITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQG 471
           +T   S IY+F+ C+F+GPL+P FSPG  DGGKNTAPLT+CP  +G QG
Sbjct: 734 VTAR-SHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICP--VGGQG 779


>gi|210147600 tripartite motif-containing 64 [Homo sapiens]
          Length = 449

 Score =  248 bits (632), Expect = 1e-65
 Identities = 159/450 (35%), Positives = 238/450 (52%), Gaps = 15/450 (3%)

Query: 7   LTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSV--CPVCRQRFLLKNLR 64
           L +   E+ C IC++ F++PV+I+CGHSFC+ C+    + G +   CP CR+     + +
Sbjct: 6   LQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKI----SEK 61

Query: 65  PNRQLANMVNNLKEISQEARE---GTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHR 121
           PN     ++  L  ++++ R     +    C +H E   LFCE D + LC  C++S +H 
Sbjct: 62  PNFNTNVVLKKLSSLARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPEHM 121

Query: 122 DHAMVPLEEAAQEYQEKLQVALGELRR-KQELAEKLEVEIAIKRADWKKTVETQKSRIHA 180
            H+  P+  AA+E +EKL   +  L    QE    L  E     +  K  V  +K  I  
Sbjct: 122 AHSHSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETRTFHS-LKDYVSVRKRIITI 180

Query: 181 EFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSA 240
           ++ +   FL EEEQR LQ LE++  E  + L + + ++ Q  + ++++  EL   CH   
Sbjct: 181 QYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHVPD 240

Query: 241 LELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWL 300
           +ELLQ+V  V  R++   ++     +PEL S C + G+  ML    V   L  +    ++
Sbjct: 241 VELLQDVRNVSARTDLAQMQKPQPVNPELTSWC-ITGVLDMLNNFRVDSALSTEMIPCYI 299

Query: 301 ILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCR 360
            LSED R V  GD   S P + +  DS+  V GAQ F SGKHYWEVDVT    W LGVC+
Sbjct: 300 SLSEDVRYVIFGDDHLSAPTDPQGVDSF-AVWGAQAFTSGKHYWEVDVTLSSNWILGVCQ 358

Query: 361 DSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGT-YPQTPLHLQVPPCQVGIFLDYEAGMVS 419
           DS     +F++ S   F+ I       Y   T  P    ++Q P  QVG+FLDY+ G VS
Sbjct: 359 DSRTADANFVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQRPLGQVGVFLDYDNGSVS 418

Query: 420 FYNITDHGSLIYSFSECAFTGPLRPFFSPG 449
           F++++  GSLIY F   +F+ PLRPFF  G
Sbjct: 419 FFDVS-KGSLIYGFPPSSFSSPLRPFFCFG 447


>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
           sapiens]
          Length = 500

 Score =  248 bits (632), Expect = 1e-65
 Identities = 173/485 (35%), Positives = 245/485 (50%), Gaps = 59/485 (12%)

Query: 12  EEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSV--CPVCRQRFLLKNLRPNRQL 69
           EE+TCPICLD F +PVSIECGH+FC+ C+ +    GG    CP CR       LRPN  L
Sbjct: 8   EELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNWAL 67

Query: 70  ANMVNNLKEISQEAREG-TQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPL 128
           A     L E +Q  R G      C  H E L LFCE D + +C VC +S++H+ HAM P+
Sbjct: 68  AR----LTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPI 123

Query: 129 EEAAQEY--------------------------QEKLQVALGELRRKQELAEKLEVEIAI 162
           +EA + Y                          +EKL  +   L  K +    L+ ++ +
Sbjct: 124 DEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQ-DVEV 182

Query: 163 KRA-DWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQ 221
           K A  WK  +++Q+ RI  EF +  NFLVEEE   LQ L K+E E  + L E   KL Q 
Sbjct: 183 KNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQT 242

Query: 222 SQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKM 281
             +L++LI E+  +  +  LELLQ    VL RSE  ++ +  + + ++++VC +P +K+M
Sbjct: 243 IASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDV-NYSLEAVKVKTVCQIPLMKEM 301

Query: 282 LRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIP------------------GNEE 323
           L+   V + L  DTA+P L+ S++ R V+   +  S P                     E
Sbjct: 302 LKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVE 361

Query: 324 RFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRR-KGHFLLSSKSGFWTIWL 382
           RF   P VLG   F SGKHYWEV+        +GVCR+ V        +S   G W I+ 
Sbjct: 362 RFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIY- 420

Query: 383 WNKQKY-EAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGP 441
           W+   Y     +P TP   +    +VG++LD   G VSFY+  D G  +++FS C+    
Sbjct: 421 WSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVD-GVHLHTFS-CSSVSR 478

Query: 442 LRPFF 446
           LRPFF
Sbjct: 479 LRPFF 483


>gi|169202375 PREDICTED: tripartite motif-containing protein
           64B-like [Homo sapiens]
          Length = 449

 Score =  247 bits (630), Expect = 2e-65
 Identities = 158/447 (35%), Positives = 235/447 (52%), Gaps = 9/447 (2%)

Query: 7   LTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSV--CPVCRQRFLLKNLR 64
           L +   E+ C IC++ F++PV+I+CGHSFC+ C+    + G +   CP CR+     N  
Sbjct: 6   LQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKTSEKPNFN 65

Query: 65  PNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHA 124
            N  L  + ++L   ++     +    C +H E   LFCE D + LC  C++S +H  H+
Sbjct: 66  TNLVLKKL-SSLARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPEHMAHS 124

Query: 125 MVPLEEAAQEYQEKLQVALGELRR-KQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFV 183
             P+  AA+E +EKL   +  L    QE    L  E +   +  K  V  +K  I  ++ 
Sbjct: 125 HSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETSTFHS-LKDYVSVRKRIITIQYQ 183

Query: 184 QQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALEL 243
           +   FL EEEQR LQ LE++  E  + L + + ++ Q  + ++++  EL   CH   + L
Sbjct: 184 KMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHMPDVVL 243

Query: 244 LQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILS 303
           LQ+V  V  R++   ++     +PEL S C + G+  ML    V   L  +    ++ LS
Sbjct: 244 LQDVRNVSARTDLAQMQKPQPVNPELTSWC-ITGVLDMLNNFRVDSALSTEMIPCYISLS 302

Query: 304 EDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSV 363
           ED R V  GD   S P + +  DS+  V GAQ F SGKHYWEVDVT    W LGVCRDS 
Sbjct: 303 EDVRYVIFGDDHLSAPTDPQGVDSFA-VWGAQAFTSGKHYWEVDVTLSSNWILGVCRDSR 361

Query: 364 RRKGHFLLSSKSGFWTIWLWNKQKYEAGT-YPQTPLHLQVPPCQVGIFLDYEAGMVSFYN 422
               +F++ S   F+ I       Y   T  P    ++Q P  +VG+FLDY+ G VSF++
Sbjct: 362 TADANFVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQRPLGRVGVFLDYDNGSVSFFD 421

Query: 423 ITDHGSLIYSFSECAFTGPLRPFFSPG 449
           ++  GSLIY F   +F+ PLRPFF  G
Sbjct: 422 VS-KGSLIYGFPPSSFSSPLRPFFCFG 447


>gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo
           sapiens]
          Length = 326

 Score =  245 bits (625), Expect = 7e-65
 Identities = 126/276 (45%), Positives = 180/276 (65%), Gaps = 6/276 (2%)

Query: 12  EEVTCPICLDPFVEPVSIECGHSFCQECISQVGKG-----GGSVCPVCRQRFLLKNLRPN 66
           EEVTCPICL+   +P+S++CGHSFCQ C++   K      G S CPVCR  +  +N+RPN
Sbjct: 11  EEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENIRPN 70

Query: 67  RQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMV 126
           R +AN+V  L+E+     EG + + CA HGE+L LFC++DGK +CW+C +S++HR H   
Sbjct: 71  RHVANIVEKLREVKLSP-EGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQEHRGHHTF 129

Query: 127 PLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQK 186
             EE AQEYQ KLQ AL  LR+KQ+ AE+LE +I  ++A WK  ++  K+ + A+F Q +
Sbjct: 130 LTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVLADFEQLR 189

Query: 187 NFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQE 246
           + L  EE  +LQ LEK+E + L+ L   E ++ QQ+Q+L+ELIS+L+ R   S +ELLQ 
Sbjct: 190 DILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGSVMELLQG 249

Query: 247 VIIVLERSESWNLKDLDITSPELRSVCHVPGLKKML 282
           V  V++R+E+  LK  +      R V   P LK ML
Sbjct: 250 VDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGML 285


>gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo
           sapiens]
          Length = 347

 Score =  245 bits (625), Expect = 7e-65
 Identities = 126/276 (45%), Positives = 180/276 (65%), Gaps = 6/276 (2%)

Query: 12  EEVTCPICLDPFVEPVSIECGHSFCQECISQVGKG-----GGSVCPVCRQRFLLKNLRPN 66
           EEVTCPICL+   +P+S++CGHSFCQ C++   K      G S CPVCR  +  +N+RPN
Sbjct: 11  EEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENIRPN 70

Query: 67  RQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMV 126
           R +AN+V  L+E+     EG + + CA HGE+L LFC++DGK +CW+C +S++HR H   
Sbjct: 71  RHVANIVEKLREVKLSP-EGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQEHRGHHTF 129

Query: 127 PLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQK 186
             EE AQEYQ KLQ AL  LR+KQ+ AE+LE +I  ++A WK  ++  K+ + A+F Q +
Sbjct: 130 LTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVLADFEQLR 189

Query: 187 NFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQE 246
           + L  EE  +LQ LEK+E + L+ L   E ++ QQ+Q+L+ELIS+L+ R   S +ELLQ 
Sbjct: 190 DILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGSVMELLQG 249

Query: 247 VIIVLERSESWNLKDLDITSPELRSVCHVPGLKKML 282
           V  V++R+E+  LK  +      R V   P LK ML
Sbjct: 250 VDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGML 285


>gi|239755486 PREDICTED: tripartite motif-containing protein
           64C-like isoform 2 [Homo sapiens]
          Length = 447

 Score =  232 bits (592), Expect = 5e-61
 Identities = 145/446 (32%), Positives = 238/446 (53%), Gaps = 9/446 (2%)

Query: 7   LTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSV--CPVCRQRFLLKNLR 64
           L +   E+ C IC++ F++PV+ +C HSFC+ C+    + G +   CP+CR+     N  
Sbjct: 6   LRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEGRAPMRCPLCRKISEKPNFN 65

Query: 65  PNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHA 124
            N  L  + +  ++ ++     +    C +H E   LFCE D + LC  C++S +H  H+
Sbjct: 66  TNVALKKLASLARQ-TRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPEHMAHS 124

Query: 125 MVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQ 184
             P+  AA+E   ++Q  + E+    ++ ++ +  +  + + +   VE +++RI   + +
Sbjct: 125 HSPIGWAAEEC--RVQKLIKEMDYLWKINQETQNNLNQETSKFCSLVEDKRNRIVYRYQK 182

Query: 185 QKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELL 244
              FL EEEQR LQ LE++ +E  + L + + ++ Q  + ++++  EL    H   +ELL
Sbjct: 183 MHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELWETYHMPDVELL 242

Query: 245 QEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSE 304
           Q+V  +  R++   +      +PEL S C + G+  ML    V   L  +    ++ LSE
Sbjct: 243 QDVGNISARTDLAQMPKPQPVNPELTSWC-ITGVLDMLNNFRVDNALSTEMTPCYISLSE 301

Query: 305 DRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVR 364
           D R+V  GD  +S P + +  +S+  V  AQ F SGKHYWEVDVT    W LGVCRDS  
Sbjct: 302 DVRRVIFGDDHRSAPMDPQGVESF-AVWCAQAFTSGKHYWEVDVTHSSNWILGVCRDSRT 360

Query: 365 RKGHFLLSSKSGFWTIWLWNKQKYEAGT-YPQTPLHLQVPPCQVGIFLDYEAGMVSFYNI 423
              + ++ S   F++I       Y   T  P    ++Q P   VG+FLDY+ G VSF+++
Sbjct: 361 ADTNIVIDSDKTFFSISSKTSNHYSLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDV 420

Query: 424 TDHGSLIYSFSECAFTGPLRPFFSPG 449
           +  GSLIY F   +F+ PLRPFF  G
Sbjct: 421 S-KGSLIYGFPPSSFSSPLRPFFCFG 445


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,531,471
Number of Sequences: 37866
Number of extensions: 933186
Number of successful extensions: 8111
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 360
Number of HSP's successfully gapped in prelim test: 712
Number of HSP's that attempted gapping in prelim test: 4740
Number of HSP's gapped (non-prelim): 2704
length of query: 475
length of database: 18,247,518
effective HSP length: 106
effective length of query: 369
effective length of database: 14,233,722
effective search space: 5252243418
effective search space used: 5252243418
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.