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Search of human proteins with 151301228
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|151301228 formin binding protein 3 [Homo sapiens]
(930 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|151301228 formin binding protein 3 [Homo sapiens] 1853 0.0
gi|72534686 Huntingtin interacting protein C isoform 1 [Homo sap... 961 0.0
gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sap... 943 0.0
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 130 4e-30
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 125 1e-28
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 79 2e-14
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 79 2e-14
gi|148727264 transcription elongation regulator 1-like [Homo sap... 75 4e-13
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 74 5e-13
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 74 5e-13
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 72 2e-12
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 72 3e-12
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 71 4e-12
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 71 5e-12
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 69 2e-11
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 69 3e-11
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 68 3e-11
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 68 3e-11
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 68 3e-11
gi|116812577 LUC7-like 2 [Homo sapiens] 67 8e-11
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 66 2e-10
gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo sap... 66 2e-10
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 66 2e-10
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 66 2e-10
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 65 3e-10
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 65 3e-10
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 65 3e-10
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 65 3e-10
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 65 4e-10
gi|52426743 cisplatin resistance-associated overexpressed protei... 64 5e-10
>gi|151301228 formin binding protein 3 [Homo sapiens]
Length = 930
Score = 1853 bits (4800), Expect = 0.0
Identities = 930/930 (100%), Positives = 930/930 (100%)
Query: 1 MCSGSGRRRSSLSPTMRPGTGAERGGLMMGHPGMHYAPMGMHPMGQRANMPPVPHGMMPQ 60
MCSGSGRRRSSLSPTMRPGTGAERGGLMMGHPGMHYAPMGMHPMGQRANMPPVPHGMMPQ
Sbjct: 1 MCSGSGRRRSSLSPTMRPGTGAERGGLMMGHPGMHYAPMGMHPMGQRANMPPVPHGMMPQ 60
Query: 61 MMPPMGGPPMGQMPGMMSSVMPGMMMSHMSQASMQPALPPGVNSMDVAAGTASGAKSMWT 120
MMPPMGGPPMGQMPGMMSSVMPGMMMSHMSQASMQPALPPGVNSMDVAAGTASGAKSMWT
Sbjct: 61 MMPPMGGPPMGQMPGMMSSVMPGMMMSHMSQASMQPALPPGVNSMDVAAGTASGAKSMWT 120
Query: 121 EHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKES 180
EHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKES
Sbjct: 121 EHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKES 180
Query: 181 RWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEECTTTSTAPVPTTEIPTT 240
RWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEECTTTSTAPVPTTEIPTT
Sbjct: 181 RWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEECTTTSTAPVPTTEIPTT 240
Query: 241 MSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNTVSGTVPVVPEPEVTSIVATVVD 300
MSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNTVSGTVPVVPEPEVTSIVATVVD
Sbjct: 241 MSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNTVSGTVPVVPEPEVTSIVATVVD 300
Query: 301 NENTVTISTEEQAQLTSTPAIQDQSVEVSSNTGEETSKQETVADFTPKKEEEESQPAKKT 360
NENTVTISTEEQAQLTSTPAIQDQSVEVSSNTGEETSKQETVADFTPKKEEEESQPAKKT
Sbjct: 301 NENTVTISTEEQAQLTSTPAIQDQSVEVSSNTGEETSKQETVADFTPKKEEEESQPAKKT 360
Query: 361 YTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQ 420
YTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQ
Sbjct: 361 YTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQ 420
Query: 421 TEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEI 480
TEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEI
Sbjct: 421 TEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEI 480
Query: 481 YEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFAEDE 540
YEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFAEDE
Sbjct: 481 YEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFAEDE 540
Query: 541 ELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNRESFQIFLDELHEHGQL 600
ELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNRESFQIFLDELHEHGQL
Sbjct: 541 ELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNRESFQIFLDELHEHGQL 600
Query: 601 HSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKG 660
HSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKG
Sbjct: 601 HSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKG 660
Query: 661 FVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKE 720
FVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKE
Sbjct: 661 FVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKE 720
Query: 721 SAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHH 780
SAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHH
Sbjct: 721 SAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHH 780
Query: 781 HSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYK 840
HSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYK
Sbjct: 781 HSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYK 840
Query: 841 KSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDS 900
KSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDS
Sbjct: 841 KSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDS 900
Query: 901 GNWDTSGSELSEGELEKRRRTLLEQLDDDQ 930
GNWDTSGSELSEGELEKRRRTLLEQLDDDQ
Sbjct: 901 GNWDTSGSELSEGELEKRRRTLLEQLDDDQ 930
>gi|72534686 Huntingtin interacting protein C isoform 1 [Homo
sapiens]
Length = 871
Score = 961 bits (2483), Expect = 0.0
Identities = 501/928 (53%), Positives = 638/928 (68%), Gaps = 105/928 (11%)
Query: 36 YAPMGMHPMGQRAN-MPPVPHGMMPQMMPPMGGPP-MGQMPGMMSSVMPGMMMSHMSQAS 93
+ PMG+ PM QR +PP+P G++P M+PPMG PP + Q+PGM+ +MPGM+M + +
Sbjct: 16 FPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTA 75
Query: 94 MQPALPPGVNSMDVAAGTASGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQ 153
A PG ++ A +++W+EH +PDGR YYYN + KQS WEKP LK+ AE
Sbjct: 76 ---ATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAEL 132
Query: 154 LLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMI 213
LLS+CPWKEYKSD+GKPYYYN+Q+KESRW +PK+L+DLE ++
Sbjct: 133 LLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLE------------------VLV 174
Query: 214 KAEESSKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANAST 273
K E + KQ++ + P P P
Sbjct: 175 KQEAAGKQQQQLPQTLQPQPPQPQPDPPP------------------------------- 203
Query: 274 SASNTVSGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTSTPAIQDQSVEVSSNTG 333
VP P P T ++ + +A Q E S++G
Sbjct: 204 ---------VPPGPTPVPTGLLEPEPGGSEDCDVL---EATQPLEQGFLQQLEEGPSSSG 251
Query: 334 EETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMK 393
+ +QE +EE + +P + +W+ +E+AKQAFKELL++K VPSNASWEQAMK
Sbjct: 252 QHQPQQE--------EEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMK 303
Query: 394 MIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTST 453
M++ DPRYSAL KLSEKKQAFNAYK Q EKEEKEEAR + KEAK++ Q FLE HE+MTST
Sbjct: 304 MVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTST 363
Query: 454 TRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDN 513
TRY++AEQ FGE+EVW + ERDR E+Y+DVLFFL+KKEKEQAKQLR+RN +ALK+ILD
Sbjct: 364 TRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDG 423
Query: 514 MANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSL 573
M++V + TTWS+AQQYLMDNP+FA+D +LQNMDKEDALICFEEHIRALE+EEEEE++++
Sbjct: 424 MSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERAR 483
Query: 574 LRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDL 633
LRERR+QRKNRE+FQ FLDELHE GQLHSMS+WMELYP +S+D+RF NMLGQPGST LDL
Sbjct: 484 LRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDL 543
Query: 634 FKFYVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLA 693
FKFYVE+LKAR+HDEKKIIKDILKD+GF VEVNT FEDF +IS KR+ LDAGNIKL
Sbjct: 544 FKFYVEELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLT 603
Query: 694 FNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAF 753
FNSLLEKAEAREREREKEEAR+M+R+E+AF+SML+QA P +EL WE++RERFV + AF
Sbjct: 604 FNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAF 663
Query: 754 EDITLESERKRIFKDFMHVLEH-ECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDD- 811
E ITLESER R+F++F+ VLE ECQH H+K +KH +K KKHH KRS S SGS+S++++
Sbjct: 664 EQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEEL 723
Query: 812 ----SHSKKKRQRSESRSASEHSSSAES---------------------ERSYKKSKKHK 846
K+R+R+ S S SE SSS +S + +K+KK K
Sbjct: 724 PPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPK 783
Query: 847 KKSKKRRHKSDSPESDAERE----KDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGN 902
KK+KKRRHKS+SPES+ + E K+ EK++E +KDR Q++E ++SP K+
Sbjct: 784 KKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTG 843
Query: 903 WDTSGSELSEGELEKRRRTLLEQLDDDQ 930
WDTS SELSEGELE+RRRTLL+QLDD Q
Sbjct: 844 WDTSESELSEGELERRRRTLLQQLDDHQ 871
>gi|29789008 Huntingtin interacting protein C isoform 2 [Homo
sapiens]
Length = 858
Score = 943 bits (2437), Expect = 0.0
Identities = 496/928 (53%), Positives = 632/928 (68%), Gaps = 112/928 (12%)
Query: 36 YAPMGMHPMGQRAN-MPPVPHGMMPQMMPPMGGPP-MGQMPGMMSSVMPGMMMSHMSQAS 93
+ PMG+ PM QR +PP+P G++P M+PPMG PP + Q+PGM+ +MPGM+M + +
Sbjct: 10 FPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTA 69
Query: 94 MQPALPPGVNSMDVAAGTASGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQ 153
A PG ++ A +++W+EH +PDGR YYYN + KQS WEKP LK+ AE
Sbjct: 70 ---ATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAEL 126
Query: 154 LLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMI 213
LLS+CPWKEYKSD+GKPYYYN+Q+KESRW +PK+L+DLE ++
Sbjct: 127 LLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLE------------------VLV 168
Query: 214 KAEESSKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANAST 273
K E + KQ++ + P P P
Sbjct: 169 KQEAAGKQQQQLPQTLQPQPPQPQPDPPP------------------------------- 197
Query: 274 SASNTVSGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTSTPAIQDQSVEVSSNTG 333
VP P P T ++ + +A Q E S++G
Sbjct: 198 ---------VPPGPTPVPTGLLEPEPGGSEDCDVL---EATQPLEQGFLQQLEEGPSSSG 245
Query: 334 EETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMK 393
+ +QE +EE + +P + +W+ +E+AKQAFKELL++K VPSNASWEQAMK
Sbjct: 246 QHQPQQE--------EEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMK 297
Query: 394 MIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTST 453
M++ DPRYSAL KLSEKKQAFNAYK Q EKEEKEEAR + KEAK++ Q FLE HE+MTST
Sbjct: 298 MVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTST 357
Query: 454 TRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDN 513
TRY++AEQ FGE+EVW + ERDR E+Y+DVLFFL+KKEKEQAKQLR+RN +ALK+ILD
Sbjct: 358 TRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDG 417
Query: 514 MANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSL 573
M++V + TTWS+AQQYLMDNP+FA+D +LQNMDKEDALICFEEHIRALE+EEEEE++++
Sbjct: 418 MSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERAR 477
Query: 574 LRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDL 633
LRERR+QRKNRE+FQ FLDELHE GQLHSMS+WMELYP +S+D+RF NMLGQPGST LDL
Sbjct: 478 LRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDL 537
Query: 634 FKFYVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLA 693
FKFYVE+LKAR+HDEKKIIKDILK VNT FEDF +IS KR+ LDAGNIKL
Sbjct: 538 FKFYVEELKARFHDEKKIIKDILK-------VNTAFEDFAHVISFDKRAAALDAGNIKLT 590
Query: 694 FNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAF 753
FNSLLEKAEAREREREKEEAR+M+R+E+AF+SML+QA P +EL WE++RERFV + AF
Sbjct: 591 FNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAF 650
Query: 754 EDITLESERKRIFKDFMHVLEH-ECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDD- 811
E ITLESER R+F++F+ VLE ECQH H+K +KH +K KKHH KRS S SGS+S++++
Sbjct: 651 EQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEEL 710
Query: 812 ----SHSKKKRQRSESRSASEHSSSAES---------------------ERSYKKSKKHK 846
K+R+R+ S S SE SSS +S + +K+KK K
Sbjct: 711 PPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPK 770
Query: 847 KKSKKRRHKSDSPESDAERE----KDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGN 902
KK+KKRRHKS+SPES+ + E K+ EK++E +KDR Q++E ++SP K+
Sbjct: 771 KKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTG 830
Query: 903 WDTSGSELSEGELEKRRRTLLEQLDDDQ 930
WDTS SELSEGELE+RRRTLL+QLDD Q
Sbjct: 831 WDTSESELSEGELERRRRTLLQQLDDHQ 858
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 130 bits (328), Expect = 4e-30
Identities = 176/753 (23%), Positives = 305/753 (40%), Gaps = 125/753 (16%)
Query: 32 PGMHYAPMGMHPMGQRANMPP-VPHGMM----------PQMMPPMGGPPMGQMPGMMSSV 80
P P+ P +PP VPH + P M+PP P G MP + V
Sbjct: 322 PAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPG-MPIPLPGV 380
Query: 81 MPGMMMSHMSQASMQPALPPGVNSMDVAAGTASGAKSM--WTEHKSPDGRTYYYNTETKQ 138
+PGM + P + P V ++ + T +GA ++ WTE+K+ DG+TYYYN T +
Sbjct: 381 LPGMA------PPIVPMIHPQV-AIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLE 433
Query: 139 STWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTI 198
STWEKP +LK E+L K + K S +P ++ ++ + KE+++
Sbjct: 434 STWEKPQELK-EKEKLEEKIK-EPIKEPSEEPLPMETEEEDPKEEPIKEIKE-------- 483
Query: 199 VAGSLITKSNLHAMIKAEESSKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAA 258
EE +EE PV T IP T VV
Sbjct: 484 --------------EPKEEEMTEEEKAAQKAKPVATAPIPGT---------PWCVVWTGD 520
Query: 259 AAAAAAAAANANASTSASNTVSGTVPV---VPEPEVTSIVATVVD-NENTVTISTEEQAQ 314
+ + + G V + EP + + T T+ + ++ Q
Sbjct: 521 ERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQ 580
Query: 315 LTSTPAIQDQSVEVSSNTGE----ETSKQETVADFTPKKE---EEESQPAKKTYTWNTKE 367
+ + ++Q + N E + K++ D +KE E E + A++ +
Sbjct: 581 FSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEA 640
Query: 368 EAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKE 427
KQ FK++L E+ V + ++WE+ + I+ DPRY L E+KQ F+ Y +EE+
Sbjct: 641 RMKQ-FKDMLLERGVSAFSTWEKELHKIVFDPRY-LLLNPKERKQVFDQYVKTRAEEERR 698
Query: 428 EARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISE-RDRLEIYEDVLF 486
E ++K +AKE F++ +E K + + + + AI + +DR ++ + +
Sbjct: 699 EKKNKIMQAKEDFKKMME-EAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVA 757
Query: 487 FLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTF-AEDEELQNM 545
KKEKE +K ++ +L N ++ + WS+ + + +P + A D
Sbjct: 758 AARKKEKEDSKTRGEKIKSDFFELLSN-HHLDSQSRWSKVKDKVESDPRYKAVDSSSMRE 816
Query: 546 DKEDALICFEEHIRALEKEEEEEKQKSL---------LRER------------------R 578
D F+++I + K + EK+K L LRER R
Sbjct: 817 D------LFKQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDRER 870
Query: 579 RQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYV 638
Q K E+ Q F L + + S SW + T+ D R+ + LF ++
Sbjct: 871 EQHKREEAIQNFKALLSDMVR-SSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHI 929
Query: 639 EDL--KARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNS 696
E L K R H + L D+ + + +T+++ II R + + K
Sbjct: 930 EALTKKKREHFRQ------LLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRK----- 978
Query: 697 LLEKAEAREREREKEEARKMKRKESAFKSMLKQ 729
++RE E+ K ++ F+++LK+
Sbjct: 979 -------KQREFEEYIRDKYITAKADFRTLLKE 1004
Score = 118 bits (296), Expect = 2e-26
Identities = 206/1002 (20%), Positives = 363/1002 (36%), Gaps = 203/1002 (20%)
Query: 14 PTMRPGTGAERGGLMMGHPGMHYAPMGMHPMGQRANMPPVPHGMMPQMMPPMGGPPMGQM 73
P MRP G+M G P P G P NMPP+P P +PP GPP Q
Sbjct: 45 PLMRPPPPF---GMMRGPPPPPRPPFGRPPFDP--NMPPMPP---PGGIPPPMGPPHLQR 96
Query: 74 PGMMSSVM------PGMMMSHMSQASMQPALPPGVNSMDVAAGTASGAKSMWTEHKSPDG 127
P M M PGMM M P PG ++ + +W E+K+PDG
Sbjct: 97 PPFMPPPMSSMPPPPGMMFP----PGMPPVTAPGTPALPPT-------EEIWVENKTPDG 145
Query: 128 RTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKE 187
+ YYYN T++S W KPD +K + L+ + + + +Q + A+ +
Sbjct: 146 KVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQA 205
Query: 188 LEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEE-----------------CTTTSTA 230
+ ++ A +A+ ++ + T T+++
Sbjct: 206 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSS 265
Query: 231 PVPTTEIPTTMSTMAAAEAAAAVVAAAAAA-----------AAAAAAANANASTSASNTV 279
P P T+ ST ++ + + A ++A + A S S
Sbjct: 266 PAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPT 325
Query: 280 SGTVPVVPEPEVTSIVATVVDN--ENTVTISTEEQAQLTS---------------TPAIQ 322
+ V VP+P ++ V + + T I + P +
Sbjct: 326 ATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMA 385
Query: 323 DQSVEVSSNTGEETSKQETVADFTPKKEEEESQPAK-KTY---------TWNTKEEAKQA 372
V + + T+A T E E + A KTY TW +E K+
Sbjct: 386 PPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKE- 444
Query: 373 FKELLKEK-RVPSNASWEQAMKMIIN--DPRYSALAKLSEKKQAFNAYKVQTEKEEKEEA 429
KE L+EK + P E+ + M DP+ + ++ E+ + + E E+E+A
Sbjct: 445 -KEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPK-------EEEMTEEEKA 496
Query: 430 RSKYKEAKES------------FQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDR 477
K K + + + T + + + + + G +V I E
Sbjct: 497 AQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPH 556
Query: 478 LEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFA 537
KK E+ K+LR + T Q++
Sbjct: 557 ------------KKGMEELKKLRHP-----------------TPTMLSIQKWQFSMSAIK 587
Query: 538 EDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKN-----RESFQIFLD 592
E++EL ED + ++ R K+ + EK+ ++ E + R+ + F D
Sbjct: 588 EEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKD 647
Query: 593 ELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLF-KFYVED----LKARYHD 647
L E G + + S+W + I D R+ + + D + K E+ K +
Sbjct: 648 MLLERG-VSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQ 706
Query: 648 EKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLA-FNSLLEKAEARER 706
K+ K ++++ F TF +F A + R ++ + A FN + A AR++
Sbjct: 707 AKEDFKKMMEEAKF--NPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFV--AAARKK 762
Query: 707 EREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIF 766
E+E + R K K F+ + ++ + W ++++ +P ++ + S R+ +F
Sbjct: 763 EKEDSKTRGEKIKSDFFELLSNHH---LDSQSRWSKVKDKVESDPRYKAVDSSSMREDLF 819
Query: 767 KDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSA 826
K ++ + +KN DS +K+ +R A
Sbjct: 820 KQYIEKI--------AKNL-------------------------DSEKEKELERQ----A 842
Query: 827 SEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQ--R 884
+S E ER +K++ + K E D ERE+ K+E+ ++ K R
Sbjct: 843 RIEASLREREREVQKARSEQTK-----------EIDREREQHKREEAIQNFKALLSDMVR 891
Query: 885 SESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQL 926
S S ++T + W+ SGS L E EK +E L
Sbjct: 892 SSDVSWSDTRRTLRKDHRWE-SGSLLEREEKEKLFNEHIEAL 932
Score = 80.9 bits (198), Expect = 5e-15
Identities = 90/393 (22%), Positives = 166/393 (42%), Gaps = 76/393 (19%)
Query: 338 KQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIIN 397
+++ V D K EE + KK N +AK+ FK++++E + A++ +
Sbjct: 680 ERKQVFDQYVKTRAEEERREKK----NKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAK 735
Query: 398 DPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENH---------- 447
D R+ A+ K+ +++ FN + K+EKE+++++ ++ K F L NH
Sbjct: 736 DSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSK 795
Query: 448 --EKMTSTTRYKKAE---------QMFGEMEVWNAISERDR-LEIYEDVLFFLSKKEK-- 493
+K+ S RYK + + + E N SE+++ LE + L ++E+
Sbjct: 796 VKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREV 855
Query: 494 -----EQAKQL-----RKRNWEALKNILDNMANVTYST--TWSEAQQYLMDNPTFAEDEE 541
EQ K++ + + EA++N ++++ S+ +WS+ ++ L + +
Sbjct: 856 QKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSL 915
Query: 542 LQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNRESFQIFLDELHEHGQLH 601
L+ +KE F EHI AL K K RE F+ LDE +
Sbjct: 916 LEREEKEK---LFNEHIEALTK------------------KKREHFRQLLDET---SAIT 951
Query: 602 SMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGF 661
S+W E+ I D R + F+ Y+ D +Y K + +LK+ F
Sbjct: 952 LTSTWKEVKKIIKEDPRCIKFSSSDRKKQRE-FEEYIRD---KYITAKADFRTLLKETKF 1007
Query: 662 VV--------EVNTTFEDFVAIISSTKRSTTLD 686
+ E + +D I+ + KR LD
Sbjct: 1008 ITYRSKKLIQESDQHLKDVEKILQNDKRYLVLD 1040
Score = 80.5 bits (197), Expect = 7e-15
Identities = 156/729 (21%), Positives = 275/729 (37%), Gaps = 125/729 (17%)
Query: 160 WKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESS 219
W EYK+ GK YYYN++T ES W KP+EL++ E + I M EE
Sbjct: 414 WTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDP 473
Query: 220 KQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNTV 279
K+E P E T AA +A A + T
Sbjct: 474 KEEPIKEIKEEP---KEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTT 530
Query: 280 SGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTS-TPAIQD-QSVEVSSNTGEETS 337
++ P+ + + E EE +L TP + Q + S + +E
Sbjct: 531 RLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKE-- 588
Query: 338 KQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIIN 397
+QE + +E E +P K K+ + K++ EK E AM+ I
Sbjct: 589 EQELM------EEINEDEPVK------AKKRKRDDNKDIDSEK--------EAAMEAEIK 628
Query: 398 DPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYK 457
R A+ L + + F ++ +F + + K+ RY
Sbjct: 629 AARERAIVPLEARMKQFKDMLLE--------------RGVSAFSTWEKELHKIVFDPRYL 674
Query: 458 KAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANV 517
++ ++R ++++ + +++E+ + K + E K +++ A
Sbjct: 675 -------------LLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEE-AKF 720
Query: 518 TYSTTWSE-AQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRE 576
T+SE A ++ D+ A ++ M +AL F E + A K+E+E+
Sbjct: 721 NPRATFSEFAAKHAKDSRFKA----IEKMKDREAL--FNEFVAAARKKEKEDS------- 767
Query: 577 RRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKF 636
+ R K + F L H L S S W ++ + SD R+ + S DLFK
Sbjct: 768 KTRGEKIKSDFFELLSNHH----LDSQSRWSKVKDKVESDPRYKAV--DSSSMREDLFKQ 821
Query: 637 YVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNS 696
Y+E KI K++ +K +E E A + +R
Sbjct: 822 YIE----------KIAKNLDSEKEKELERQARIE---ASLRERERE-------------- 854
Query: 697 LLEKAEAREREREKEEARKMKRKESA--FKSMLKQAAPPIELDAVWEDIRERFVKEPAFE 754
++KA + + + E + KR+E+ FK++L D W D R K+ +E
Sbjct: 855 -VQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVR--SSDVSWSDTRRTLRKDHRWE 911
Query: 755 DITL--ESERKRIFKDFMHVLEHECQHHHSKNKKHS---------KKSKKHHRKRSRSRS 803
+L E++++F + + L + + H + + K+ KK ++ R
Sbjct: 912 SGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIK 971
Query: 804 GSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDA 863
S SD KK+R+ E ++ A+ K++K +SKK +SD D
Sbjct: 972 FSSSD-----RKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDV 1026
Query: 864 ER--EKDKK 870
E+ + DK+
Sbjct: 1027 EKILQNDKR 1035
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 125 bits (315), Expect = 1e-28
Identities = 181/778 (23%), Positives = 313/778 (40%), Gaps = 121/778 (15%)
Query: 10 SSLSPTMRPGTGAERGGLMMGHPGMH---YAPMGMHPMGQRAN-MPPVPHGMMPQMMPPM 65
S +PT+ T A + P H P H + Q +P P M+P P+
Sbjct: 311 SVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPL 370
Query: 66 GGPPMGQMPG--MMSSVM-PGMMMSHMSQASMQPALPPGVNSM-----DVAAGTAS---- 113
G P+ +PG MM V P + ++ + P + P + M +AA A+
Sbjct: 371 PGMPI-PLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGA 429
Query: 114 GAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYY 173
A S WTE+K+ DG+TYYYN T +STWEKP +LK E+L K + K S +P
Sbjct: 430 TAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELK-EKEKLEEKIK-EPIKEPSEEPLPM 487
Query: 174 NSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEECTTTSTAPVP 233
++ ++ + KE+++ EE +EE PV
Sbjct: 488 ETEEEDPKEEPIKEIKE----------------------EPKEEEMTEEEKAAQKAKPVA 525
Query: 234 TTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNTVSGTVPV---VPEPE 290
T IP T VV + + + G V + EP
Sbjct: 526 TAPIPGT---------PWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPP 576
Query: 291 VTSIVATVVD-NENTVTISTEEQAQLTSTPAIQDQSVEVSSNTGE----ETSKQETVADF 345
+ + T T+ + ++ Q + + ++Q + N E + K++ D
Sbjct: 577 HKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDI 636
Query: 346 TPKKE---EEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYS 402
+KE E E + A++ + KQ FK++L E+ V + ++WE+ + I+ DPRY
Sbjct: 637 DSEKEAAMEAEIKAARERAIVPLEARMKQ-FKDMLLERGVSAFSTWEKELHKIVFDPRY- 694
Query: 403 ALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQM 462
L E+KQ F+ Y +EE+ E ++K +AKE F++ +E K + +
Sbjct: 695 LLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMME-EAKFNPRATFSEFAAK 753
Query: 463 FGEMEVWNAISE-RDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYST 521
+ + AI + +DR ++ + + KKEKE +K ++ +L N ++ +
Sbjct: 754 HAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSN-HHLDSQS 812
Query: 522 TWSEAQQYLMDNPTF-AEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSL------- 573
WS+ + + +P + A D D F+++I + K + EK+K L
Sbjct: 813 RWSKVKDKVESDPRYKAVDSSSMRED------LFKQYIEKIAKNLDSEKEKELERQARIE 866
Query: 574 --LRER------------------RRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTI 613
LRER R Q K E+ Q F L + + S SW + T+
Sbjct: 867 ASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVR-SSDVSWSDTRRTL 925
Query: 614 SSDIRFTNMLGQPGSTALDLFKFYVEDL--KARYHDEKKIIKDILKDKGFVVEVNTTFED 671
D R+ + LF ++E L K R H + L D+ + + +T+++
Sbjct: 926 RKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQ------LLDETSAITLTSTWKE 979
Query: 672 FVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQ 729
II R + + K ++RE E+ K ++ F+++LK+
Sbjct: 980 VKKIIKEDPRCIKFSSSDRK------------KQREFEEYIRDKYITAKADFRTLLKE 1025
Score = 114 bits (284), Expect = 5e-25
Identities = 209/1026 (20%), Positives = 369/1026 (35%), Gaps = 230/1026 (22%)
Query: 14 PTMRPGTGAERGGLMMGHPGMHYAPMGMHPMGQRANMPPVPHGMMPQMMPPMGGPPMGQM 73
P MRP G+M G P P G P NMPP+P P +PP GPP Q
Sbjct: 45 PLMRPPPPF---GMMRGPPPPPRPPFGRPPFDP--NMPPMPP---PGGIPPPMGPPHLQR 96
Query: 74 PGMMSSVM------PGMMMSHMSQASMQPALPPGVNSMDVAAGTASGAKSMWTEHKSPDG 127
P M M PGMM M P PG ++ + +W E+K+PDG
Sbjct: 97 PPFMPPPMSSMPPPPGMMFP----PGMPPVTAPGTPALPPT-------EEIWVENKTPDG 145
Query: 128 RTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKE 187
+ YYYN T++S W KPD +K + L+ + + + +Q + A+ +
Sbjct: 146 KVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQA 205
Query: 188 LEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEE-----------------CTTTSTA 230
+ ++ A +A+ ++ + T T+++
Sbjct: 206 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSS 265
Query: 231 PVPTTEIPTTMSTMAAAEAAAAVVAAAAAA-----------AAAAAAANANASTSASNTV 279
P P T+ ST ++ + + A ++A + A S S
Sbjct: 266 PAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPT 325
Query: 280 SGTVPVVPEPEVTSIVATV---VDNENT---------------------VTISTEEQAQL 315
+ V VP+P ++ V V T + + Q+
Sbjct: 326 ATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQI 385
Query: 316 TSTPAIQDQSVEVSSNTG-----------------EETSKQETVADFTPKKEEEESQPAK 358
S P ++ + ++ TG + T+A T E E + A
Sbjct: 386 VSCPYVKTVA---TTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTAD 442
Query: 359 -KTY---------TWNTKEEAKQAFKELLKEK-RVPSNASWEQAMKMIIN--DPRYSALA 405
KTY TW +E K+ KE L+EK + P E+ + M DP+ +
Sbjct: 443 GKTYYYNNRTLESTWEKPQELKE--KEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIK 500
Query: 406 KLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKES------------FQRFLENHEKMTST 453
++ E+ + + E E+E+A K K + + + T
Sbjct: 501 EIKEEPK-------EEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRL 553
Query: 454 TRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDN 513
+ + + + + G +V I E KK E+ K+LR
Sbjct: 554 SMWDRPDDLIGRADVDKIIQEPPH------------KKGMEELKKLRHP----------- 590
Query: 514 MANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSL 573
+ T Q++ E++EL ED + ++ R K+ + EK+ ++
Sbjct: 591 ------TPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAM 644
Query: 574 LRERRRQRKN-----RESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGS 628
E + R+ + F D L E G + + S+W + I D R+ + +
Sbjct: 645 EAEIKAARERAIVPLEARMKQFKDMLLERG-VSAFSTWEKELHKIVFDPRYLLLNPKERK 703
Query: 629 TALDLF-KFYVED----LKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRST 683
D + K E+ K + K+ K ++++ F TF +F A + R
Sbjct: 704 QVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKF--NPRATFSEFAAKHAKDSRFK 761
Query: 684 TLDAGNIKLA-FNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWED 742
++ + A FN + A AR++E+E + R K K F+ + ++ + W
Sbjct: 762 AIEKMKDREALFNEFV--AAARKKEKEDSKTRGEKIKSDFFELLSNHH---LDSQSRWSK 816
Query: 743 IRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSR 802
++++ +P ++ + S R+ +FK ++ + +KN
Sbjct: 817 VKDKVESDPRYKAVDSSSMREDLFKQYIEKI--------AKNL----------------- 851
Query: 803 SGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESD 862
DS +K+ +R A +S E ER +K++ + K E D
Sbjct: 852 --------DSEKEKELERQ----ARIEASLREREREVQKARSEQTK-----------EID 888
Query: 863 AEREKDKKEKDRESEKDRTRQ--RSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRR 920
ERE+ K+E+ ++ K RS S ++T + W+ SGS L E EK
Sbjct: 889 REREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWE-SGSLLEREEKEKLFN 947
Query: 921 TLLEQL 926
+E L
Sbjct: 948 EHIEAL 953
Score = 80.9 bits (198), Expect = 5e-15
Identities = 90/393 (22%), Positives = 166/393 (42%), Gaps = 76/393 (19%)
Query: 338 KQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIIN 397
+++ V D K EE + KK N +AK+ FK++++E + A++ +
Sbjct: 701 ERKQVFDQYVKTRAEEERREKK----NKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAK 756
Query: 398 DPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENH---------- 447
D R+ A+ K+ +++ FN + K+EKE+++++ ++ K F L NH
Sbjct: 757 DSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSK 816
Query: 448 --EKMTSTTRYKKAE---------QMFGEMEVWNAISERDR-LEIYEDVLFFLSKKEK-- 493
+K+ S RYK + + + E N SE+++ LE + L ++E+
Sbjct: 817 VKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREV 876
Query: 494 -----EQAKQL-----RKRNWEALKNILDNMANVTYST--TWSEAQQYLMDNPTFAEDEE 541
EQ K++ + + EA++N ++++ S+ +WS+ ++ L + +
Sbjct: 877 QKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSL 936
Query: 542 LQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNRESFQIFLDELHEHGQLH 601
L+ +KE F EHI AL K K RE F+ LDE +
Sbjct: 937 LEREEKEK---LFNEHIEALTK------------------KKREHFRQLLDET---SAIT 972
Query: 602 SMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGF 661
S+W E+ I D R + F+ Y+ D +Y K + +LK+ F
Sbjct: 973 LTSTWKEVKKIIKEDPRCIKFSSSDRKKQRE-FEEYIRD---KYITAKADFRTLLKETKF 1028
Query: 662 VV--------EVNTTFEDFVAIISSTKRSTTLD 686
+ E + +D I+ + KR LD
Sbjct: 1029 ITYRSKKLIQESDQHLKDVEKILQNDKRYLVLD 1061
Score = 80.5 bits (197), Expect = 7e-15
Identities = 156/729 (21%), Positives = 275/729 (37%), Gaps = 125/729 (17%)
Query: 160 WKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMIKAEESS 219
W EYK+ GK YYYN++T ES W KP+EL++ E + I M EE
Sbjct: 435 WTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDP 494
Query: 220 KQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNTV 279
K+E P E T AA +A A + T
Sbjct: 495 KEEPIKEIKEEP---KEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTT 551
Query: 280 SGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTS-TPAIQD-QSVEVSSNTGEETS 337
++ P+ + + E EE +L TP + Q + S + +E
Sbjct: 552 RLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKE-- 609
Query: 338 KQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIIN 397
+QE + +E E +P K K+ + K++ EK E AM+ I
Sbjct: 610 EQELM------EEINEDEPVK------AKKRKRDDNKDIDSEK--------EAAMEAEIK 649
Query: 398 DPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYK 457
R A+ L + + F ++ +F + + K+ RY
Sbjct: 650 AARERAIVPLEARMKQFKDMLLE--------------RGVSAFSTWEKELHKIVFDPRYL 695
Query: 458 KAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANV 517
++ ++R ++++ + +++E+ + K + E K +++ A
Sbjct: 696 -------------LLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEE-AKF 741
Query: 518 TYSTTWSE-AQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRE 576
T+SE A ++ D+ A ++ M +AL F E + A K+E+E+
Sbjct: 742 NPRATFSEFAAKHAKDSRFKA----IEKMKDREAL--FNEFVAAARKKEKEDS------- 788
Query: 577 RRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKF 636
+ R K + F L H L S S W ++ + SD R+ + S DLFK
Sbjct: 789 KTRGEKIKSDFFELLSNHH----LDSQSRWSKVKDKVESDPRYKAV--DSSSMREDLFKQ 842
Query: 637 YVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNS 696
Y+E KI K++ +K +E E A + +R
Sbjct: 843 YIE----------KIAKNLDSEKEKELERQARIE---ASLRERERE-------------- 875
Query: 697 LLEKAEAREREREKEEARKMKRKESA--FKSMLKQAAPPIELDAVWEDIRERFVKEPAFE 754
++KA + + + E + KR+E+ FK++L D W D R K+ +E
Sbjct: 876 -VQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVR--SSDVSWSDTRRTLRKDHRWE 932
Query: 755 DITL--ESERKRIFKDFMHVLEHECQHHHSKNKKHS---------KKSKKHHRKRSRSRS 803
+L E++++F + + L + + H + + K+ KK ++ R
Sbjct: 933 SGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIK 992
Query: 804 GSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDA 863
S SD KK+R+ E ++ A+ K++K +SKK +SD D
Sbjct: 993 FSSSD-----RKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDV 1047
Query: 864 ER--EKDKK 870
E+ + DK+
Sbjct: 1048 EKILQNDKR 1056
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 79.0 bits (193), Expect = 2e-14
Identities = 56/225 (24%), Positives = 105/225 (46%), Gaps = 20/225 (8%)
Query: 700 KAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLE 759
++E RERERE E ++ K++ + + ++ + + E RER KE E E
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 760 SERKRIFKDFMHVLEHECQHHHSKNKKHSKKSK-KHHRKRSRSRSGSDSDDDDSHSKKKR 818
ERK+ + +NK+ +K K K K+ R R+ + + + ++KR
Sbjct: 95 RERKK-------------RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKR 141
Query: 819 QRSESRSASEHSSSAESERSYKKSKKHK---KKSKKRRHKSDSPESDAEREKDKKEKDRE 875
+ + R + E ER +K ++ K +K ++R+ K ER + +++K+RE
Sbjct: 142 EERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERE 201
Query: 876 SEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRR 920
++ R R++ K + KK+ KD T+ E G+ E++ R
Sbjct: 202 RKERRERKKERKKKEERKKERQKDR---QTNWREKERGKRERKER 243
Score = 64.3 bits (155), Expect = 5e-10
Identities = 35/143 (24%), Positives = 63/143 (44%)
Query: 783 KNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKS 842
+ + KK ++ KR R R + KK ++ E R + E++ +K
Sbjct: 54 ERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKE 113
Query: 843 KKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGN 902
K+ KK+ K+R S + +E+ K+E+ +E E+ + + E + K KK+ K G
Sbjct: 114 KRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGE 173
Query: 903 WDTSGSELSEGELEKRRRTLLEQ 925
+ E E +KR R E+
Sbjct: 174 KEEERKEKERKERKKRERNRKER 196
Score = 61.6 bits (148), Expect = 3e-09
Identities = 45/190 (23%), Positives = 87/190 (45%), Gaps = 31/190 (16%)
Query: 699 EKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITL 758
+K E ++ ERE+++ R+ K + + ++ E ++ +ER KE
Sbjct: 86 KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKE-------- 137
Query: 759 ESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKR 818
ERKR E + K ++ ++ +K +KR R + G ++ +K++
Sbjct: 138 --ERKR---------EERKERERKKEEREKERERKERKKRERKQVGEKEEE-----RKEK 181
Query: 819 QRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEK 878
+R E + + + ER K+ ++ KK+ KK+ E ER+KD++ RE E+
Sbjct: 182 ERKERKKRERNRKERKKERERKERRERKKERKKKE------ERKKERQKDRQTNWREKER 235
Query: 879 DRTRQRSESK 888
+ R+R E K
Sbjct: 236 GK-RERKERK 244
Score = 54.3 bits (129), Expect = 5e-07
Identities = 36/161 (22%), Positives = 72/161 (44%), Gaps = 11/161 (6%)
Query: 777 CQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESE 836
C H + +S+ R+R + +S KK+R+ E R E + E
Sbjct: 22 CSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRK-REREKERKRE 80
Query: 837 RSYKKSKKHKKKSKKRRHK-------SDSPESDAEREKDKKEKDRESEKDRTRQRSESKH 889
R K+ K +KK ++ R K + E + ++K+KKE+ R S++ + R+R E +
Sbjct: 81 RGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERK 140
Query: 890 KSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDDQ 930
+ +K+ + + E E +KR R + + ++++
Sbjct: 141 REERKERERKK---EEREKERERKERKKRERKQVGEKEEER 178
Score = 38.9 bits (89), Expect = 0.022
Identities = 43/176 (24%), Positives = 76/176 (43%), Gaps = 7/176 (3%)
Query: 335 ETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKM 394
E+ +++ + +K E E + ++ K E K+ +E K +R N E+ K
Sbjct: 56 ESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKR 115
Query: 395 IINDP----RYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLEN-HEK 449
+ R S K E+K+ + + E+E K+E R K +E KE +R + EK
Sbjct: 116 KKKEKKERGRTSKEGKERERKEE-RKREERKERERKKEEREKERERKERKKRERKQVGEK 174
Query: 450 MTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQL-RKRNW 504
++ E+ E ER+R E E K+E+++ +Q R+ NW
Sbjct: 175 EEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNW 230
Score = 35.8 bits (81), Expect = 0.19
Identities = 45/198 (22%), Positives = 78/198 (39%), Gaps = 16/198 (8%)
Query: 418 KVQTEKE---EKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISE 474
+++T KE E+E R K + +E +R E K + KK E+ E E E
Sbjct: 44 EIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRRE 103
Query: 475 RDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNP 534
++ E E KKEK++ + K E + E ++ +
Sbjct: 104 KENKEGEEKEK--RKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERK 161
Query: 535 TFAEDEELQNMDKEDALICFEEHIRALE----KEEEEEKQKSLLRERRRQRKNRESFQIF 590
+ E Q +KE+ E R KE ++E+++ RER+++RK +E
Sbjct: 162 ERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKE----- 216
Query: 591 LDELHEHGQLHSMSSWME 608
E + Q ++W E
Sbjct: 217 --ERKKERQKDRQTNWRE 232
Score = 30.4 bits (67), Expect = 8.0
Identities = 34/156 (21%), Positives = 65/156 (41%), Gaps = 3/156 (1%)
Query: 349 KEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRV-PSNASWEQAMKMIINDPRYSALAKL 407
+E E +K + E K+ +E K KR E+ K + + +
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
Query: 408 SEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQR-FLENHEKMTSTTRYKKAEQMFGEM 466
+++ N + EK +K+E + + + +KE +R E ++ R +K E+ E
Sbjct: 99 KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER 158
Query: 467 EVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKR 502
E +R+R ++ E K+ KE+ K+ R R
Sbjct: 159 E-RKERKKRERKQVGEKEEERKEKERKERKKRERNR 193
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 79.0 bits (193), Expect = 2e-14
Identities = 65/217 (29%), Positives = 93/217 (42%), Gaps = 31/217 (14%)
Query: 704 REREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERK 763
R+REREKE R +R K E + E RER ++ + ++ E ++
Sbjct: 352 RDREREKENERGRRRDRDYDKERGN------EREKERERSRERSKEQRSRGEV--EEKKH 403
Query: 764 RIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSES 823
+ KD H +K+ SKK KKH R RSR R K R RS S
Sbjct: 404 KEDKD---------DRRHRDDKRDSKKEKKHSRSRSRER-------------KHRSRSRS 441
Query: 824 RSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQ 883
R+A + S S E+S K + K+KS KR +D+ + K+E EK R R
Sbjct: 442 RNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRS 501
Query: 884 RS-ESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRR 919
RS E HK + S D S+ E E ++++
Sbjct: 502 RSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQ 538
Score = 69.3 bits (168), Expect = 2e-11
Identities = 68/251 (27%), Positives = 122/251 (48%), Gaps = 16/251 (6%)
Query: 688 GNIKLAFNSLLEKAEARER-ERE-KEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRE 745
G+ +F+ LE+ + R+R ERE KE ++ +R S + + ++ + E R+
Sbjct: 285 GHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRD 344
Query: 746 RFV-KEPAFEDITLESER-KRIFKDFMHVLEHECQHHHSKNKKHSKKSK-------KHHR 796
R + + E+ER +R +D+ +E + ++++ SK+ + K H+
Sbjct: 345 RKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHK 404
Query: 797 KRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKS 856
+ R D D DS +KK RS SR +H S + S + K+S+ + K K +HK+
Sbjct: 405 EDKDDRRHRD-DKRDSKKEKKHSRSRSRE-RKHRSRSRSRNAGKRSRS-RSKEKSSKHKN 461
Query: 857 DSPESDAEREKDKKEKDRES-EKDRTRQRSESKHKSPKKKTGKD-SGNWDTSGSELSEGE 914
+S E +R + + +S EK + R+ S SK KS K+ K+ S D S S+ +
Sbjct: 462 ESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDK 521
Query: 915 LEKRRRTLLEQ 925
++RR +EQ
Sbjct: 522 HDRRRSQSIEQ 532
Score = 66.6 bits (161), Expect = 1e-10
Identities = 57/242 (23%), Positives = 99/242 (40%), Gaps = 20/242 (8%)
Query: 699 EKAEAREREREKEEARKMKR--------KESAFKSMLKQAAPPIELDAVWEDIRERFVKE 750
E AE +R E+ +R +R + S +S ++ D E +ER E
Sbjct: 246 EGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLE 305
Query: 751 PAFEDITLESERKR-IFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDD 809
++ E R R I + + H S+++ +K + R R R +
Sbjct: 306 REAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRR 365
Query: 810 DDSHSKKKR--QRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAE--- 864
D K+R +R + R S S + R + KKHK+ RRH+ D +S E
Sbjct: 366 RDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKH 425
Query: 865 ---REKDKKEKDRESEKD---RTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKR 918
R +++K + R ++ R+R RS+ K K ++ + S SGS+ +EK
Sbjct: 426 SRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKS 485
Query: 919 RR 920
++
Sbjct: 486 KK 487
Score = 64.3 bits (155), Expect = 5e-10
Identities = 50/186 (26%), Positives = 87/186 (46%), Gaps = 18/186 (9%)
Query: 755 DITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRS--------GSD 806
D +++ ++I KD E +H + + ++S R RSRS GS
Sbjct: 230 DQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSS 289
Query: 807 SDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAERE 866
S D + +K+RQR E R A E RS + + ++ + RH+S S D R+
Sbjct: 290 SFDRELEREKERQRLE-REAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRD--RK 346
Query: 867 KDKKEKDRESEKD----RTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTL 922
D++++DRE EK+ R R R K + +++ ++ + S + S GE+E+++
Sbjct: 347 GDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSR-ERSKEQRSRGEVEEKKHK- 404
Query: 923 LEQLDD 928
E DD
Sbjct: 405 -EDKDD 409
Score = 59.3 bits (142), Expect = 2e-08
Identities = 47/177 (26%), Positives = 78/177 (44%), Gaps = 7/177 (3%)
Query: 699 EKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITL 758
+K ERE+E+E +R+ +++ + + ++ + D D + KE
Sbjct: 371 DKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRS 430
Query: 759 ESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKR 818
+ R + + K+ KH +SK+ K RSRSGS D KKR
Sbjct: 431 RERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNK--RSRSGSQGRTDSVEKSKKR 488
Query: 819 QRSESRSASEHSSSAESERSYKK----SKKHKKKSKKRRHKSDSPESDAEREKDKKE 871
+ S S+ S S ++ ERS+K+ SK K +RR +S ES ++ K+K E
Sbjct: 489 EHSPSKEKSRKRSRSK-ERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDE 544
>gi|148727264 transcription elongation regulator 1-like [Homo
sapiens]
Length = 586
Score = 74.7 bits (182), Expect = 4e-13
Identities = 52/173 (30%), Positives = 90/173 (52%), Gaps = 9/173 (5%)
Query: 335 ETSKQETVADFTPKKEEEESQPAKKTYTWNTK-----EEAKQAFKELLKEKRVPSNASWE 389
+T + T +PK EE + + K T T + EE F+++L E+ V + ++WE
Sbjct: 415 KTKRNRTEGCGSPKPEEAKRED-KGTRTPPPQILLPLEERVTHFRDMLLERGVSAFSTWE 473
Query: 390 QAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEK 449
+ + I+ DPRY L E+KQ F + KEE +E +SK AKE F++ LE K
Sbjct: 474 KELHKIVFDPRY-LLLNSEERKQIFEQFVKTRIKEEYKEKKSKLLLAKEEFKKLLE-ESK 531
Query: 450 MTSTTRYKKAEQMFGEMEVWNAISER-DRLEIYEDVLFFLSKKEKEQAKQLRK 501
++ T +K+ + +G + + + +R D+ + + L K++KE +LRK
Sbjct: 532 VSPRTTFKEFAEKYGRDQRFRLVQKRKDQEHFFNQFILILKKRDKENRLRLRK 584
Score = 30.4 bits (67), Expect = 8.0
Identities = 39/196 (19%), Positives = 76/196 (38%), Gaps = 22/196 (11%)
Query: 144 PDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSL 203
P L TP + W + + + K ++ NS +S W P+E G++ +
Sbjct: 143 PSALATPIGK-----SWIDKRIPNCKIFFNNSFALDSTWIHPEESRFFHGHEKPRLL--- 194
Query: 204 ITKSNLHAMIKAEESSKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAA 263
+N A+ + + T AP P IP ++ A+ A AAAAA
Sbjct: 195 ---ANQVAVSLSRPAPASRPLPTVVLAPQP---IPGGCHNSLKVTSSPAIAIATAAAAAM 248
Query: 264 AAAANANASTSASNTVSGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTSTPAIQD 323
+ N + ++V P +T + + V+ + E+ ++ PA+
Sbjct: 249 VSVDPENLRGPSPSSVQ------PRHFLTLAPIKIPLRTSPVSDTRTERGRVARPPALML 302
Query: 324 QSVEVSSNTGEETSKQ 339
++ + S G++ K+
Sbjct: 303 RAQK--SRDGDKEDKE 316
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 74.3 bits (181), Expect = 5e-13
Identities = 62/241 (25%), Positives = 110/241 (45%), Gaps = 12/241 (4%)
Query: 700 KAEAREREREKEEAR---KMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDI 756
K ++ RER K +R + KRK++ K K+ + + E +ER ++ ++
Sbjct: 356 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 415
Query: 757 TLESERKRIF-KDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSK 815
+ ER++ KD E E + H K++ K+ ++ K + D+ K
Sbjct: 416 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 475
Query: 816 KKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRH-KSDSPESDAEREKDKKEKDR 874
K R S +AS S S+ ER ++S+ + + + K S S + R ++KK+K R
Sbjct: 476 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR 535
Query: 875 ESEKD-----RTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDD 929
E E+D R R+RS S KS + GK+ + + + L E E K + + + DD
Sbjct: 536 EKERDHISERRERERSTSMRKSSNDRDGKE--KLEKNSTSLKEKEHNKEPDSSVSKEVDD 593
Query: 930 Q 930
+
Sbjct: 594 K 594
Score = 73.9 bits (180), Expect = 6e-13
Identities = 48/141 (34%), Positives = 73/141 (51%), Gaps = 13/141 (9%)
Query: 784 NKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSK 843
N++ +S+ H R +SRS S SHS++KR +S+ RS S + S + + +
Sbjct: 301 NERKGGRSRSHTRSKSRSSS-------KSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKS 353
Query: 844 KHKKKSKKR-RHKSDSPESDAEREKDK----KEKDRESEKDRTRQRSESKHKSPKKKTGK 898
HKK+SK R R KS S ++ KD KEK+R EKDR ++R K + +K+ GK
Sbjct: 354 PHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK 413
Query: 899 DSGNWDTSGSELSEGELEKRR 919
+ D + E + EK R
Sbjct: 414 NKDR-DKEREKDREKDKEKDR 433
Score = 68.6 bits (166), Expect = 3e-11
Identities = 50/172 (29%), Positives = 77/172 (44%), Gaps = 9/172 (5%)
Query: 726 MLKQAAPPIELDAVWEDIRER--FVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSK 783
M QAA EL+ V + +RE F+ + +ERK H S
Sbjct: 266 MTPQAAAK-ELEEVMKRVREAQSFISAAIEPESGKSNERKG-----GRSRSHTRSKSRSS 319
Query: 784 NKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSK 843
+K HS++ + + RSRS + S S D K + S+S S + S K+
Sbjct: 320 SKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKD 379
Query: 844 KHKKKSKKRRHKSDSPESDAEREKDK-KEKDRESEKDRTRQRSESKHKSPKK 894
+K +K R K E + EREK++ KEK+R KDR ++R + + K +K
Sbjct: 380 TREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 431
Score = 67.4 bits (163), Expect = 6e-11
Identities = 43/149 (28%), Positives = 73/149 (48%), Gaps = 19/149 (12%)
Query: 787 HSKKSKKHHRKRSRSRSGSDSDDDDSHSK-------------KKRQRSESRSAS-EHSSS 832
H K+SK R++SRSRS S D+ K K+R+R + R E +
Sbjct: 355 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 414
Query: 833 AESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKE-KDRESEKDRTRQRSESKHKS 891
+ ++ +K ++ K+ + R + E D ++EK+K++ K++E EKDR+++ E + K
Sbjct: 415 KDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKD 474
Query: 892 PKKKTGKDSGNWDTSGSELSEGELEKRRR 920
K +T S N S S +RRR
Sbjct: 475 KKSRTPPRSYN----ASRRSRSSSRERRR 499
Score = 58.2 bits (139), Expect = 4e-08
Identities = 55/224 (24%), Positives = 103/224 (45%), Gaps = 28/224 (12%)
Query: 700 KAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLE 759
K + RE+ERE+E+ R+ +++ K K+ E D E RER ++ +D E
Sbjct: 391 KEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK--EKDREREREKEHEKDRDKE 448
Query: 760 SERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQ 819
E+++ + E + ++K+ +K KK + R+ RS + S S S+++R+
Sbjct: 449 KEKEQ---------DKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRR 499
Query: 820 RSE---------SRSASEHSSSAESERSYKKS--KKHKKK---SKKRRHKSDSPESDAER 865
R S++ SS + S RS K K+ K++ S++R + + +
Sbjct: 500 RRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSN 559
Query: 866 EKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSE 909
++D KEK EK+ T + + +K P K+ + D +E
Sbjct: 560 DRDGKEK---LEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 600
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/160 (23%), Positives = 64/160 (40%), Gaps = 11/160 (6%)
Query: 699 EKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITL 758
EK + +E+EREK+ ++++ K K K PP +A R R +
Sbjct: 450 EKEQDKEKEREKDRSKEIDEKRKKDK---KSRTPPRSYNA---SRRSRSSSRERRRRRSR 503
Query: 759 ESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKH-----HRKRSRSRSGSDSDDDDSH 813
S R + S+NKK K+ K+ R+R RS S S +D
Sbjct: 504 SSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDG 563
Query: 814 SKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRR 853
+K + S S EH+ +S S + K ++++ +
Sbjct: 564 KEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 603
Score = 30.8 bits (68), Expect = 6.1
Identities = 35/180 (19%), Positives = 76/180 (42%), Gaps = 29/180 (16%)
Query: 406 KLSEKKQAFNAY-KVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFG 464
K S+ K ++ + ++ ++++ ++S +K+ +S +R ++ + S + K +
Sbjct: 327 KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRER-RKSRSRSHSRDKRKDTREKIK 385
Query: 465 EMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWS 524
E E + E+DR +KE+E+ K+ K D
Sbjct: 386 EKE---RVKEKDR------------EKEREREKEREKEKERGKNKDRDKEREK------D 424
Query: 525 EAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNR 584
+ D E E ++ DKE +E + EKE E+++ K + +R++ +K+R
Sbjct: 425 REKDKEKDREREREKEHEKDRDKE------KEKEQDKEKEREKDRSKEIDEKRKKDKKSR 478
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 74.3 bits (181), Expect = 5e-13
Identities = 62/241 (25%), Positives = 110/241 (45%), Gaps = 12/241 (4%)
Query: 700 KAEAREREREKEEAR---KMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDI 756
K ++ RER K +R + KRK++ K K+ + + E +ER ++ ++
Sbjct: 240 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 299
Query: 757 TLESERKRIF-KDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSK 815
+ ER++ KD E E + H K++ K+ ++ K + D+ K
Sbjct: 300 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 359
Query: 816 KKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRH-KSDSPESDAEREKDKKEKDR 874
K R S +AS S S+ ER ++S+ + + + K S S + R ++KK+K R
Sbjct: 360 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR 419
Query: 875 ESEKD-----RTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDD 929
E E+D R R+RS S KS + GK+ + + + L E E K + + + DD
Sbjct: 420 EKERDHISERRERERSTSMRKSSNDRDGKE--KLEKNSTSLKEKEHNKEPDSSVSKEVDD 477
Query: 930 Q 930
+
Sbjct: 478 K 478
Score = 73.9 bits (180), Expect = 6e-13
Identities = 48/141 (34%), Positives = 73/141 (51%), Gaps = 13/141 (9%)
Query: 784 NKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSK 843
N++ +S+ H R +SRS S SHS++KR +S+ RS S + S + + +
Sbjct: 185 NERKGGRSRSHTRSKSRSSS-------KSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKS 237
Query: 844 KHKKKSKKR-RHKSDSPESDAEREKDK----KEKDRESEKDRTRQRSESKHKSPKKKTGK 898
HKK+SK R R KS S ++ KD KEK+R EKDR ++R K + +K+ GK
Sbjct: 238 PHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK 297
Query: 899 DSGNWDTSGSELSEGELEKRR 919
+ D + E + EK R
Sbjct: 298 NKDR-DKEREKDREKDKEKDR 317
Score = 68.6 bits (166), Expect = 3e-11
Identities = 50/172 (29%), Positives = 77/172 (44%), Gaps = 9/172 (5%)
Query: 726 MLKQAAPPIELDAVWEDIRER--FVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSK 783
M QAA EL+ V + +RE F+ + +ERK H S
Sbjct: 150 MTPQAAAK-ELEEVMKRVREAQSFISAAIEPESGKSNERKG-----GRSRSHTRSKSRSS 203
Query: 784 NKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSK 843
+K HS++ + + RSRS + S S D K + S+S S + S K+
Sbjct: 204 SKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKD 263
Query: 844 KHKKKSKKRRHKSDSPESDAEREKDK-KEKDRESEKDRTRQRSESKHKSPKK 894
+K +K R K E + EREK++ KEK+R KDR ++R + + K +K
Sbjct: 264 TREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 315
Score = 67.4 bits (163), Expect = 6e-11
Identities = 43/149 (28%), Positives = 73/149 (48%), Gaps = 19/149 (12%)
Query: 787 HSKKSKKHHRKRSRSRSGSDSDDDDSHSK-------------KKRQRSESRSAS-EHSSS 832
H K+SK R++SRSRS S D+ K K+R+R + R E +
Sbjct: 239 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 298
Query: 833 AESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKE-KDRESEKDRTRQRSESKHKS 891
+ ++ +K ++ K+ + R + E D ++EK+K++ K++E EKDR+++ E + K
Sbjct: 299 KDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKD 358
Query: 892 PKKKTGKDSGNWDTSGSELSEGELEKRRR 920
K +T S N S S +RRR
Sbjct: 359 KKSRTPPRSYN----ASRRSRSSSRERRR 383
Score = 58.2 bits (139), Expect = 4e-08
Identities = 55/224 (24%), Positives = 103/224 (45%), Gaps = 28/224 (12%)
Query: 700 KAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLE 759
K + RE+ERE+E+ R+ +++ K K+ E D E RER ++ +D E
Sbjct: 275 KEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK--EKDREREREKEHEKDRDKE 332
Query: 760 SERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQ 819
E+++ + E + ++K+ +K KK + R+ RS + S S S+++R+
Sbjct: 333 KEKEQ---------DKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRR 383
Query: 820 RSE---------SRSASEHSSSAESERSYKKS--KKHKKK---SKKRRHKSDSPESDAER 865
R S++ SS + S RS K K+ K++ S++R + + +
Sbjct: 384 RRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSN 443
Query: 866 EKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSE 909
++D KEK EK+ T + + +K P K+ + D +E
Sbjct: 444 DRDGKEK---LEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 484
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/160 (23%), Positives = 64/160 (40%), Gaps = 11/160 (6%)
Query: 699 EKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITL 758
EK + +E+EREK+ ++++ K K K PP +A R R +
Sbjct: 334 EKEQDKEKEREKDRSKEIDEKRKKDK---KSRTPPRSYNA---SRRSRSSSRERRRRRSR 387
Query: 759 ESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKH-----HRKRSRSRSGSDSDDDDSH 813
S R + S+NKK K+ K+ R+R RS S S +D
Sbjct: 388 SSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDG 447
Query: 814 SKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRR 853
+K + S S EH+ +S S + K ++++ +
Sbjct: 448 KEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 487
Score = 30.8 bits (68), Expect = 6.1
Identities = 35/180 (19%), Positives = 76/180 (42%), Gaps = 29/180 (16%)
Query: 406 KLSEKKQAFNAY-KVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFG 464
K S+ K ++ + ++ ++++ ++S +K+ +S +R ++ + S + K +
Sbjct: 211 KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRER-RKSRSRSHSRDKRKDTREKIK 269
Query: 465 EMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWS 524
E E + E+DR +KE+E+ K+ K D
Sbjct: 270 EKE---RVKEKDR------------EKEREREKEREKEKERGKNKDRDKEREK------D 308
Query: 525 EAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNR 584
+ D E E ++ DKE +E + EKE E+++ K + +R++ +K+R
Sbjct: 309 REKDKEKDREREREKEHEKDRDKE------KEKEQDKEKEREKDRSKEIDEKRKKDKKSR 362
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 72.4 bits (176), Expect = 2e-12
Identities = 57/204 (27%), Positives = 92/204 (45%), Gaps = 42/204 (20%)
Query: 740 WEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKK---SKKHHR 796
WE+++++ + E E K + +++ LE + S N+ SKK KK +
Sbjct: 41 WEEVKKQLENKKTGSKALAEFEEK-MNENWKKELEKSREKLLSGNESSSKKRERKKKRKK 99
Query: 797 KRSRSRSGSDSDDDDSHS--------------KKKRQRS-ESRSASEHSSSAESERSYKK 841
K RS S S S D S S KKK+ RS +S +S H S +ES+ S KK
Sbjct: 100 KSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKK 159
Query: 842 SKKHK------------KKSKKRRHKSDSP-----------ESDAEREKDKKEKDRESEK 878
KK K K +K+ + D P E D + +K ++ ++RE K
Sbjct: 160 KKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAK 219
Query: 879 DRTRQRSESKHKSPKKKTGKDSGN 902
++ +++ + +HK KK K SG+
Sbjct: 220 EKVKKKKKKQHKKHSKKKKKKSGS 243
Score = 49.3 bits (116), Expect = 2e-05
Identities = 41/187 (21%), Positives = 77/187 (41%), Gaps = 24/187 (12%)
Query: 705 EREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKR 764
E +K E +K ++K+S S ++ + ED ++ + +R++
Sbjct: 85 ESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKK------------QGKRRK 132
Query: 765 IFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESR 824
K+ + H K S K KK +S+ + + D K+K+ + +
Sbjct: 133 KKKNRSYKSSQSSTHESESESKESVKKKK----KSKDETEKEKDVRSLSKKRKKSYPDDK 188
Query: 825 SASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQR 884
S SS SE Y++ + KKK + + E E+ K KK+K + + +++
Sbjct: 189 PLSSESS---SESDYEEDVQAKKK-----RRCEEREQAKEKVKKKKKKQHKKHSKKKKKK 240
Query: 885 SESKHKS 891
S S HKS
Sbjct: 241 SGSSHKS 247
Score = 43.9 bits (102), Expect = 7e-04
Identities = 45/167 (26%), Positives = 74/167 (44%), Gaps = 16/167 (9%)
Query: 700 KAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKE----PAFED 755
++ +++RER+K+ +K R S+ S ++ D + + R K+ + +
Sbjct: 85 ESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQS 144
Query: 756 ITLESE---RKRIFKDFMHVLEHECQHH-HSKNKKHSKKSKKHHRKRSRSRSGSDSDDDD 811
T ESE ++ + K E E + S +KK K S S S SD ++D
Sbjct: 145 STHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDV 204
Query: 812 SHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDS 858
KK+R E A+ + KK K+HKK SKK++ KS S
Sbjct: 205 QAKKKRR--------CEEREQAKEKVKKKKKKQHKKHSKKKKKKSGS 243
Score = 38.5 bits (88), Expect = 0.029
Identities = 37/143 (25%), Positives = 61/143 (42%), Gaps = 32/143 (22%)
Query: 792 KKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKK 851
K+ K++ S++ ++ ++ + + KK E S E S +S K++ KK
Sbjct: 46 KQLENKKTGSKALAEFEEKMNENWKK----------ELEKSREKLLSGNESSSKKRERKK 95
Query: 852 RRHK-------------SDSPESDAEREKDKKEKDRESEKDRT---------RQRSESKH 889
+R K S S SD+E E+ K+ K R+ +K+R+ SESK
Sbjct: 96 KRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKE 155
Query: 890 KSPKKKTGKDSGNWDTSGSELSE 912
KKK KD + LS+
Sbjct: 156 SVKKKKKSKDETEKEKDVRSLSK 178
Score = 33.5 bits (75), Expect = 0.94
Identities = 30/137 (21%), Positives = 66/137 (48%), Gaps = 11/137 (8%)
Query: 329 SSNTGEETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASW 388
SS++ ++ +E KK++ S + ++ T ++ E+K++ K K+K+
Sbjct: 113 SSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVK---KKKKSKDETEK 169
Query: 389 EQAMKMIINDPR--YSALAKLSEKKQAFNAYK--VQTEK----EEKEEARSKYKEAKESF 440
E+ ++ + + Y LS + + + Y+ VQ +K EE+E+A+ K K+ K+
Sbjct: 170 EKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQ 229
Query: 441 QRFLENHEKMTSTTRYK 457
+ +K S + +K
Sbjct: 230 HKKHSKKKKKKSGSSHK 246
Score = 30.8 bits (68), Expect = 6.1
Identities = 43/206 (20%), Positives = 89/206 (43%), Gaps = 24/206 (11%)
Query: 387 SWEQAMKMIINDPRYS-ALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLE 445
+WE+ K + N S ALA+ EK + K+E E++R K ES + E
Sbjct: 40 TWEEVKKQLENKKTGSKALAEFEEKMN-------ENWKKELEKSREKLLSGNESSSKKRE 92
Query: 446 NHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQA-KQLRKRNW 504
+K R KK+ + ++ S E E KK+K ++ K +
Sbjct: 93 RKKK-----RKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTH 147
Query: 505 EALKNILDNMANVTYSTTWSEAQQYLMD-----NPTFAEDEELQNMDKEDALICFEEHIR 559
E+ +++ S +E ++ + ++ +D+ L + ++ +EE ++
Sbjct: 148 ESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSES--DYEEDVQ 205
Query: 560 ALEK---EEEEEKQKSLLRERRRQRK 582
A +K EE E+ ++ + +++++Q K
Sbjct: 206 AKKKRRCEEREQAKEKVKKKKKKQHK 231
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 71.6 bits (174), Expect = 3e-12
Identities = 56/227 (24%), Positives = 109/227 (48%), Gaps = 17/227 (7%)
Query: 699 EKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDIT- 757
E+ RER+R+ E R+ +R+ + ++ E + ED +E E T
Sbjct: 160 ERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETE 219
Query: 758 LESERKRIF---KDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHS 814
E+ERKR +D E E + ++ ++ S++ + ++R R R D D D
Sbjct: 220 TETERKRQTDRERDRQRKTERE-REKQAERERASERETERDKERERER---DRDRDRDRR 275
Query: 815 KKKRQRSESRSASEHSS-SAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKK-EK 872
+K+R+R R + E+ER ++ ++ +++ ++ R + E + ERE+ ++ E+
Sbjct: 276 QKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETER 335
Query: 873 DRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRR 919
DRE E++R R+R + ++TG++ G +E E E+ R
Sbjct: 336 DREKERERKRKRQTEMDRERNRQTGRE-------GRRQAERERERER 375
Score = 70.1 bits (170), Expect = 9e-12
Identities = 44/219 (20%), Positives = 101/219 (46%), Gaps = 2/219 (0%)
Query: 704 REREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERK 763
RER+R+++ R+ +++ ++ ++ E + + R+R ++ E T ++
Sbjct: 230 RERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQR 289
Query: 764 RIFKDFMHVLEHECQHHHSKNKKHSKK-SKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSE 822
R +D + E Q + ++ ++K ++ R+R R R D + ++KR+R
Sbjct: 290 RTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQT 349
Query: 823 SRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDK-KEKDRESEKDRT 881
+ + R + ++ +++ + R+ + E + +R++D+ KE++R++EKDR
Sbjct: 350 EMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRD 409
Query: 882 RQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRR 920
QR K + +K + G E +G R R
Sbjct: 410 GQRETEKQREREKDRESERGRERGREREKQKGRERDRER 448
Score = 69.3 bits (168), Expect = 2e-11
Identities = 51/240 (21%), Positives = 112/240 (46%), Gaps = 21/240 (8%)
Query: 699 EKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITL 758
E RER REK+ RK R + K+ + + + +ER ++ +
Sbjct: 74 ETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETER 133
Query: 759 ESERKR---------------IFKDFMHVLEHECQHHHSKNK---KHSKKSKKHHRKRSR 800
E ER R K+ + E Q +N+ + +K+++ R+R R
Sbjct: 134 EGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERER 193
Query: 801 SRSGSDSDDDDSHSKKKRQRSESR-SASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSP 859
R ++ +D HS++ R+R R + +E +++R + +K +++ +K+ + +
Sbjct: 194 QRE-KENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERAS 252
Query: 860 ESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRR 919
E + ER+K+ +E++R+ ++DR R++ E + ++ +K+ + + +T + E E+ R
Sbjct: 253 ERETERDKE-RERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER 311
Score = 68.6 bits (166), Expect = 3e-11
Identities = 58/222 (26%), Positives = 98/222 (44%), Gaps = 9/222 (4%)
Query: 704 REREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERK 763
RERERE+E + +RK + +Q E + E RER + D E ER
Sbjct: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAE--RERASERETERDKERERERD 267
Query: 764 RIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSES 823
R E E Q K ++ +++ ++ RKR R R + + +++R+R
Sbjct: 268 RDRDRDRRQKERERQTDR-KRQRRTERDRETERKRERQRERERERERNRKRERERERERE 326
Query: 824 RSAS-EHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDK-KEKDRES---EK 878
R E E ER K+ ++ + ++ R AERE+++ +E+DR+S +
Sbjct: 327 RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARERE 386
Query: 879 DRTRQRSESKHKSPKKKTGKD-SGNWDTSGSELSEGELEKRR 919
+R R R + K +++T KD G +T E + E R
Sbjct: 387 ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESER 428
Score = 63.5 bits (153), Expect = 9e-10
Identities = 47/233 (20%), Positives = 97/233 (41%), Gaps = 15/233 (6%)
Query: 699 EKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITL 758
E+ RER+R++E+ R +++ + + D E R+R ++
Sbjct: 106 ERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDR 165
Query: 759 ESER---KRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSK 815
E +R + K+ + + + ++ K++ H +R R R + ++ K
Sbjct: 166 ERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERK 225
Query: 816 KKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRE 875
++ R R E ER + ++ + + R K E D +R++D+++K+RE
Sbjct: 226 RQTDRERDR-----QRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERE 280
Query: 876 SEKDRTRQR-------SESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRT 921
+ DR RQR +E K + +++ + N E E E++R T
Sbjct: 281 RQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRET 333
Score = 62.8 bits (151), Expect = 1e-09
Identities = 47/228 (20%), Positives = 100/228 (43%), Gaps = 22/228 (9%)
Query: 704 REREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERK 763
RER R+KE R+ +++++ ++ K RER ++ ER+
Sbjct: 54 RERNRQKERERRREKRQTERETDRK---------------RERRREKDRHRKRDRHRERQ 98
Query: 764 RIFKDFMHVLEHECQHHHSKNKKHSK-KSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSE 822
R + E E Q ++++ K ++++ R+R R G D + +++R+R
Sbjct: 99 RDREK-----ERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR 153
Query: 823 SRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTR 882
+ E + ER + + +K+ ++ +++ + E + +REK+ K +DR SE+ R R
Sbjct: 154 D-AEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRER 212
Query: 883 QRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDDQ 930
+R ++K D +E + +R R + + D+
Sbjct: 213 ERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDK 260
Score = 62.0 bits (149), Expect = 2e-09
Identities = 50/210 (23%), Positives = 94/210 (44%), Gaps = 16/210 (7%)
Query: 699 EKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITL 758
E+ + RERER+++ R ++KE ++ K+ E D E RER + +
Sbjct: 257 ERDKERERERDRDRDRDRRQKERERQTDRKRQRRT-ERDRETERKRERQRERERERERNR 315
Query: 759 ESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKH-----HRKRSRSRSGSDSDDDDSH 813
+ ER+R + E + + + K+ +K K+ R R R G + +
Sbjct: 316 KRERER---ERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERE 372
Query: 814 SKKKRQRSESRSASEHSSSA------ESERSYKKSKKHKKKSKKRRHKSDSPESDAEREK 867
+++R R +R E E ER +K + +++++K+R + ES+ RE+
Sbjct: 373 RERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRER 432
Query: 868 DK-KEKDRESEKDRTRQRSESKHKSPKKKT 896
+ +EK + E+DR RQ + K+ T
Sbjct: 433 GREREKQKGRERDRERQTDRQAGRQRKRST 462
Score = 59.7 bits (143), Expect = 1e-08
Identities = 39/144 (27%), Positives = 75/144 (52%), Gaps = 11/144 (7%)
Query: 782 SKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKK 841
S+ + S++S + R ++ +D DD + + +K+R+R + +E + + ER +K
Sbjct: 27 SRRRPGSQESPRR-RGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREK 85
Query: 842 SKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSG 901
+H+K+ + R + D E + ER+ D +E+DR+ EK+R RQ+ + + + G+D
Sbjct: 86 D-RHRKRDRHRERQRDR-EKERERQTD-RERDRQREKERNRQKERERETEREGERGRDR- 141
Query: 902 NWDTSGSELSE----GELEKRRRT 921
T G E E E+ R+T
Sbjct: 142 --QTDGQRERERQRDAEKERERQT 163
Score = 59.3 bits (142), Expect = 2e-08
Identities = 46/235 (19%), Positives = 112/235 (47%), Gaps = 13/235 (5%)
Query: 700 KAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLE 759
+ + RERE E+E R R+ + +Q E + + R+R + ++ E
Sbjct: 123 RQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERERE 182
Query: 760 SERK-RIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKR 818
R+ R ++ E++ + HS+ + ++ ++ + R R +D + +K
Sbjct: 183 KNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQ---TDRERDRQRKTE 239
Query: 819 QRSESRSASEHSSSAESERSYKKSKKHKK-KSKKRRHKSDSPESDAEREKDKKEKDRESE 877
+ E ++ E +S E+ER ++ ++ + + + RR K ++D +R++ + E+DRE+E
Sbjct: 240 REREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQR-RTERDRETE 298
Query: 878 K----DRTRQRSESKHKSPKKKTGKD---SGNWDTSGSELSEGELEKRRRTLLEQ 925
+ R R+R +++ +++ ++ +T E E +++R+T +++
Sbjct: 299 RKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDR 353
Score = 36.2 bits (82), Expect = 0.15
Identities = 48/265 (18%), Positives = 107/265 (40%), Gaps = 19/265 (7%)
Query: 322 QDQSVEVSSNTGEETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKR 381
++++ + S G E ++ T +K + + + ++ T +E KQA +E E+
Sbjct: 198 ENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKT--EREREKQAERERASERE 255
Query: 382 VPSNASWEQAMKMIIN-DPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESF 440
+ E+ + D R + +++K+ + + + ++E R + +E + +
Sbjct: 256 TERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNR 315
Query: 441 QRFLENH-----EKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQ 495
+R E E+ T R ++ E+ ER+R E ++ + +
Sbjct: 316 KRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG-----RRQAERE 370
Query: 496 AKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFE 555
++ R+R+ ++ + + + +Q D E E+ + +K+
Sbjct: 371 RERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKD------R 424
Query: 556 EHIRALEKEEEEEKQKSLLRERRRQ 580
E R E+ E EKQK R+R RQ
Sbjct: 425 ESERGRERGREREKQKGRERDRERQ 449
Score = 32.7 bits (73), Expect = 1.6
Identities = 53/283 (18%), Positives = 108/283 (38%), Gaps = 25/283 (8%)
Query: 322 QDQSVEVSSNTGEETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKR 381
+D+ E T E +Q +++E Q ++ T E + + +E+
Sbjct: 99 RDREKERERQTDRERDRQ--------REKERNRQKERERETEREGERGRDRQTDGQRERE 150
Query: 382 VPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKV-----QTEKEEKEEARSKYKEA 436
+A E+ + R + + E+++ N + Q EKE K E R +
Sbjct: 151 RQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGR 210
Query: 437 KESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQA 496
+ +R E + T ++ Q E E +ER+R S++E E+
Sbjct: 211 ERERERETETETERKRQTDRERDRQRKTEREREKQ-AERERA----------SERETERD 259
Query: 497 KQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEE 556
K+ R+R + ++ T ++ D T + E + ++E E
Sbjct: 260 KE-RERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRE 318
Query: 557 HIRALEKEEEEEKQKSLLRERRRQRKNRESFQIFLDELHEHGQ 599
R E+E E +++ RE+ R+RK + ++ + + G+
Sbjct: 319 RERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGR 361
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 71.2 bits (173), Expect = 4e-12
Identities = 50/245 (20%), Positives = 107/245 (43%), Gaps = 14/245 (5%)
Query: 668 TFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMK-RKESAFKS- 725
T +D A+ TKR + G I++ + A +E + +K K +KE F+
Sbjct: 189 TNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRF 248
Query: 726 ----------MLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEH 775
+ K+ IE++ D+ R + + LE E+ + K+ + +
Sbjct: 249 PVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKE 308
Query: 776 ECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAES 835
+ + ++ ++ ++ R+R R R + + + R R++ R + +
Sbjct: 309 RRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDR-DRDRERDR 367
Query: 836 ERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDK-KEKDRESEKDRTRQRSESKHKSPKK 894
+R ++S K + R KS E + ERE+++ +E++RE E++R R+R + + +K
Sbjct: 368 DRDRERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREK 427
Query: 895 KTGKD 899
+D
Sbjct: 428 DKKRD 432
Score = 52.0 bits (123), Expect = 3e-06
Identities = 107/560 (19%), Positives = 204/560 (36%), Gaps = 56/560 (10%)
Query: 63 PPMGGP------PMGQMPGMMSSVMPGMMMSHMSQASMQPA---LPPGVNSMDVAAGTAS 113
PPMG P P Q PG V PG M + + M PA L P V+ + G
Sbjct: 10 PPMGIPALPPGIPPPQFPGFPPPVPPGTPMIPVPMSIMAPAPTVLVPTVSMVGKHLGARK 69
Query: 114 GAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKC----PWKEYKSDSGK 169
+ + K D T + EK D+ QLL+KC WK + SGK
Sbjct: 70 DHPGL--KAKENDENCGPTTTVFVGNISEKASDML--IRQLLAKCGLVLSWKRVQGASGK 125
Query: 170 PY---YYNSQTKESRWAKPKELEDLE-GYQNTIVAGSLITKSNL---HAMIKAEESSKQE 222
+ + ES + L DL+ G + +V TK+ L A KA + +
Sbjct: 126 LQAFGFCEYKEPESTLRALRLLHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKASNGNARP 185
Query: 223 ECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNTVS-- 280
E T E T + A V+ ++ A + +++
Sbjct: 186 ETVTNDDEEALDEE---TKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKE 242
Query: 281 ------GTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTS--TPAIQDQSVEVSSNT 332
P++P P +T ++ E E++ L S +D ++
Sbjct: 243 DIFRRFPVAPLIPYPLITKEDINAIEME-------EDKRDLISREISKFRDTHKKLEEEK 295
Query: 333 GEETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAM 392
G++ +++ + ++E E + ++ +E ++ KE +E+ + ++
Sbjct: 296 GKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTK 355
Query: 393 KMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTS 452
+ + R + E+ N + ++ ++ ++ R + +E + +R E+
Sbjct: 356 ERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERER---ERERERE 412
Query: 453 TTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILD 512
R ++ E+ + E D + YE +EKE A Q R +NWE +
Sbjct: 413 REREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKT 472
Query: 513 NMANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALI----CFEEHIRALEKEEEEE 568
++ + E E + D++D ++ +R EKE E +
Sbjct: 473 REYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEAD 532
Query: 569 KQKSLLRERRRQRKNRESFQ 588
+ R+R+R+++ E +
Sbjct: 533 E-----RDRKREKEELEEIR 547
Score = 48.1 bits (113), Expect = 4e-05
Identities = 50/237 (21%), Positives = 103/237 (43%), Gaps = 19/237 (8%)
Query: 699 EKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFV--------KE 750
E+ REREREKE+ R+ +R+ + K+ + + + RER
Sbjct: 326 EREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSR 385
Query: 751 PAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDD 810
D E ER+R ++ E E + + ++ ++ +K +KR R D++
Sbjct: 386 EKSRDRERERERERE-REREREREREREREREREREREREREKD-KKRDRE-----EDEE 438
Query: 811 DSHSKKKRQRS--ESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKD 868
D++ ++K +R E +A + R KK+++++K++++ + +A+R K+
Sbjct: 439 DAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKE 498
Query: 869 KKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQ 925
E + D R + K + + + D + + ELE+ R+ LL +
Sbjct: 499 FLEDYDDDRDDPKYYRGSALQKRLRDREKEMEA--DERDRKREKEELEEIRQRLLAE 553
Score = 40.8 bits (94), Expect = 0.006
Identities = 35/168 (20%), Positives = 76/168 (45%), Gaps = 15/168 (8%)
Query: 693 AFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPA 752
A+ L+ E RER++ +E ++ +R+E + M K+A E ++D R+ +P
Sbjct: 456 AYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRD----DPK 511
Query: 753 FEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDS 812
+ + +R R + M E +++K K+ + R+R + D D+
Sbjct: 512 YYRGSALQKRLRDREKEMEADE--------RDRKREKEELEEIRQRLLAEG---HPDPDA 560
Query: 813 HSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPE 860
++ Q +E R + ESE ++ ++ ++K ++ + + PE
Sbjct: 561 ELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPE 608
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 70.9 bits (172), Expect = 5e-12
Identities = 47/196 (23%), Positives = 84/196 (42%), Gaps = 30/196 (15%)
Query: 700 KAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLE 759
K E RERE+ K E K +++E K K+ RER E
Sbjct: 37 KKERREREKRKREREKERKRERGKKEKKKRKK------------RER----------GKE 74
Query: 760 SERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQ 819
ERKR E E Q + K+ K+ K+ ++ + R + +++R+
Sbjct: 75 RERKR--------KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERE 126
Query: 820 RSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKD 879
+ R + R +K +K + K +++R K E + +RE+++KE+ +E E+
Sbjct: 127 NKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERK 186
Query: 880 RTRQRSESKHKSPKKK 895
R+R + + K +KK
Sbjct: 187 ERRERKKERKKERRKK 202
Score = 70.1 bits (170), Expect = 9e-12
Identities = 48/203 (23%), Positives = 97/203 (47%), Gaps = 27/203 (13%)
Query: 699 EKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITL 758
E+ E +R+RE+E+ RK +R + K K+ E +ER
Sbjct: 39 ERREREKRKREREKERKRERGKKEKKKRKKR-----------ERGKER------------ 75
Query: 759 ESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSK-KHHRKRSRSRSGSDSDDDDSHSKKK 817
E +RK K E E + + KK +K + + RK+ + R + ++ +K+
Sbjct: 76 ERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR 135
Query: 818 RQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESE 877
++R + + E E ER ++ K+ K+K ++R K + + ++E+++KE+ RE +
Sbjct: 136 KKRRKKKRRKER--KREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER-RERK 192
Query: 878 KDRTRQRSESKHKSPKKKTGKDS 900
K+R ++R + K + +KT + +
Sbjct: 193 KERKKERRKKKERKKDRKTDRQT 215
Score = 64.7 bits (156), Expect = 4e-10
Identities = 34/151 (22%), Positives = 73/151 (48%), Gaps = 8/151 (5%)
Query: 777 CQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSD------DDDSHSKKKRQRSESRSASEHS 830
C H + + KK R+R + + + + + +KKR+R + R
Sbjct: 22 CSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKE 81
Query: 831 SSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHK 890
+ + +K ++ +KK KK+R + + +++K++KE++RE+++ R R+R + + K
Sbjct: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKK 141
Query: 891 SPKK--KTGKDSGNWDTSGSELSEGELEKRR 919
+K K K+ G + + + E EK+R
Sbjct: 142 KRRKERKREKERGKRERKRKKRKKEEREKKR 172
Score = 62.4 bits (150), Expect = 2e-09
Identities = 54/223 (24%), Positives = 96/223 (43%), Gaps = 8/223 (3%)
Query: 699 EKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITL 758
E+ + R+RER K+E +K K++E + K+ + E R + KE +
Sbjct: 49 EREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQ 108
Query: 759 ESERKRIFKDFMHVLEHEC-QHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKK 817
R+R K E E Q K KK KK ++ RKR + R G K++
Sbjct: 109 RGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER-GKRERKRKKRKKEE 167
Query: 818 RQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESE 877
R++ R+ E E + ++ K+ KK+ +K++ + ++D + + RES
Sbjct: 168 REKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESA 227
Query: 878 KDRTRQRSESKHKSPKKKTGKD----SGNWDTSGSELSEGELE 916
+R +++ TG D N S E+++GE+E
Sbjct: 228 FNRVTVTGVFRYRI--FHTGLDHFPIKTNILLSRHEVNDGEIE 268
Score = 53.5 bits (127), Expect = 9e-07
Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 8/113 (7%)
Query: 811 DSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKK 870
+S KK+R+ E R E ER ++ KK KKK KKR + EREK +K
Sbjct: 33 ESERKKERREREKRKRER-----EKERKRERGKKEKKKRKKRERGKERERKRKEREKQRK 87
Query: 871 ---EKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRR 920
EK+R K ++R + ++K K+ + + E + +KRR+
Sbjct: 88 ERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRK 140
Score = 47.4 bits (111), Expect = 6e-05
Identities = 34/112 (30%), Positives = 56/112 (50%), Gaps = 7/112 (6%)
Query: 812 SHSKKKRQRSESRSASEHSSSAESERSYKKSKKHK--KKSKKRRHKSDSPESDAEREKDK 869
SH K + ES E + +R +K +K + KK KK+R K E ERE+ +
Sbjct: 23 SHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKR---ERGKERERKR 79
Query: 870 KEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWD-TSGSELSEGELEKRRR 920
KE++++ ++ R ++R + K K KK+ K G + E E E E ++R
Sbjct: 80 KEREKQRKERREKERRKRK-KEKKKRERKQRGRRERKKKKERKERERENKQR 130
Score = 33.1 bits (74), Expect = 1.2
Identities = 42/213 (19%), Positives = 86/213 (40%), Gaps = 23/213 (10%)
Query: 299 VDNENTVTISTEEQ---AQLTSTPAIQDQSVEVSSNTGEETSKQETVADFTPKKEEEESQ 355
+ + V ++TE Q S P Q +S E K+E + ++ ++E +
Sbjct: 5 ISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKK 64
Query: 356 PAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFN 415
KK +E ++ ++ KE+R + EKK+
Sbjct: 65 KRKKRERGKERERKRKEREKQRKERREKERRK------------------RKKEKKKRER 106
Query: 416 AYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISER 475
+ + E+++K+E + + +E K+ +R + K + +K E+ G+ E ++
Sbjct: 107 KQRGRRERKKKKERKERERENKQRRERKRKKRRK-KKRRKERKREKERGKRERKRKKRKK 165
Query: 476 DRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALK 508
+ E + KKE+E+ K+ R+R E K
Sbjct: 166 EEREKKRERNRKERKKERER-KERRERKKERKK 197
Score = 31.2 bits (69), Expect = 4.7
Identities = 18/62 (29%), Positives = 30/62 (48%)
Query: 864 EREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLL 923
+RE ++K++ RE EK + + E K + KK+ K E E EK+R+
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 924 EQ 925
E+
Sbjct: 91 EK 92
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 69.3 bits (168), Expect = 2e-11
Identities = 41/132 (31%), Positives = 70/132 (53%), Gaps = 13/132 (9%)
Query: 778 QHHHSKNKKHSKKSKKH-------HRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHS 830
+HH+S+++ S++ K+ HR RSRS+ G + D SKK +SE + EHS
Sbjct: 37 KHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKK--HKSEEHNDKEHS 94
Query: 831 SSAESER---SYKKSKKHKKKSKK-RRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSE 886
S ER S +HK+K +K R +S S ER + ++R+ + R+R+R +
Sbjct: 95 SDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKK 154
Query: 887 SKHKSPKKKTGK 898
S+ +S ++K +
Sbjct: 155 SRSRSRERKKSR 166
Score = 65.1 bits (157), Expect = 3e-10
Identities = 38/137 (27%), Positives = 64/137 (46%), Gaps = 5/137 (3%)
Query: 788 SKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKK 847
S ++ KHH RSRSRS D+ +K R RS S+ H S +S + +K + + K
Sbjct: 32 SPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDK 91
Query: 848 -----KSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGN 902
K ++R + S++ E +R++ K + R + R+R+R +KK+ S
Sbjct: 92 EHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRE 151
Query: 903 WDTSGSELSEGELEKRR 919
S S E + + R
Sbjct: 152 RKKSRSRSRERKKSRSR 168
Score = 64.3 bits (155), Expect = 5e-10
Identities = 44/154 (28%), Positives = 74/154 (48%), Gaps = 19/154 (12%)
Query: 776 ECQHHHSKNKKHSK-KSKKHHRK-----RSRSRSGSDSDDDDSHSKKKRQRSESRSASEH 829
E + H SK+K K KS++H+ K + R R S + +D H +K+R+ S RS H
Sbjct: 69 EGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS---H 125
Query: 830 SSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEK---DRTRQRSE 886
S S ER ++ + +KKS+ R + S + K + + RE ++ R+R RS
Sbjct: 126 SRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 185
Query: 887 SKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRR 920
+H++ + + S S + +EK RR
Sbjct: 186 HRHRTRSRSRTR-------SRSRDRKKRIEKPRR 212
Score = 54.7 bits (130), Expect = 4e-07
Identities = 53/213 (24%), Positives = 90/213 (42%), Gaps = 37/213 (17%)
Query: 700 KAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLE 759
++ +RER+R+ + + R S K + + +D + K D
Sbjct: 44 RSRSRERKRKSDNEGRKHRSRSRSKEGRRHES---------KDKSSKKHKSEEHNDKEHS 94
Query: 760 SERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQ 819
S++ R + ++ E+ H K +K S + + H R RSR R H + R+
Sbjct: 95 SDKGR---ERLNSSENGEDRHKRKERK-SSRGRSHSRSRSRER---------RHRSRSRE 141
Query: 820 RSESRSAS-EHSSSAESERSYKKSKKHKKKSKKR-----------RHKSDSPESDAEREK 867
R +SRS S E S R KKS+ ++ K+R RH++ S R +
Sbjct: 142 RKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSR 201
Query: 868 DKKEKDRESEKDRTRQRSESKHKSPKKKTGKDS 900
D+K++ EK R RS S+ SP G+++
Sbjct: 202 DRKKR---IEKPRRFSRSLSRTPSPPPFRGRNT 231
Score = 47.0 bits (110), Expect = 8e-05
Identities = 39/133 (29%), Positives = 55/133 (41%), Gaps = 14/133 (10%)
Query: 802 RSGSDSDDDDSHSKKKRQRSE---SRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDS 858
R G + KK+++SE S AS+H S RS ++ +K + +K R +S S
Sbjct: 8 RDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRS 67
Query: 859 PESDAEREKDKKEK--------DRESEKDRTRQR---SESKHKSPKKKTGKDSGNWDTSG 907
E KDK K D+E D+ R+R SE+ K+K K S S
Sbjct: 68 KEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 127
Query: 908 SELSEGELEKRRR 920
S E R R
Sbjct: 128 SRSRERRHRSRSR 140
Score = 45.1 bits (105), Expect = 3e-04
Identities = 59/233 (25%), Positives = 88/233 (37%), Gaps = 33/233 (14%)
Query: 706 REREKEEARKMKRKESAFKSMLKQAAPPI-ELDAVWEDIRERFVKEPAFEDITLESERKR 764
+ R + +++ +R ES KS K + + + + RER ED ERK
Sbjct: 60 KHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKS 119
Query: 765 IFKDFMHVLEHECQHHHSKNKKHSKKSKKH------------HRKRSRSRSGSDSDDDDS 812
+ H + H + KKS+ RK+SRSR S
Sbjct: 120 S-RGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR---------S 169
Query: 813 HSKKKRQRSESRSASEHSSSAES-ERSYKKSKKHKKKSKKRRHKSDS--------PESDA 863
+K+R RS SRS S H S R+ +S+ KK+ +K R S S P
Sbjct: 170 RERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGR 229
Query: 864 EREKDKKEK-DRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGEL 915
D +E R E+ + Q K K+K + + T GS L+ L
Sbjct: 230 NTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGGSVLNVAAL 282
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 68.6 bits (166), Expect = 3e-11
Identities = 42/122 (34%), Positives = 67/122 (54%), Gaps = 7/122 (5%)
Query: 781 HSKNKKHSK-KSKKHHRKRSRSRSGSDSDDDDSHSK-KKRQRSESRSASEHSSSAESERS 838
+S+++ HS+ +S+ H ++SRSRSGS SHSK + R RS SRS S+ S ++S
Sbjct: 185 YSRSRSHSRSRSRSRHSRKSRSRSGSSK---SSHSKSRSRSRSGSRSRSKSRSRSQSRSR 241
Query: 839 YKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKD--RTRQRSESKHKSPKKKT 896
KK K +K R +S S + KD+ E+ ++ + + + RS S+HKS K
Sbjct: 242 SKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSR 301
Query: 897 GK 898
+
Sbjct: 302 SR 303
Score = 62.8 bits (151), Expect = 1e-09
Identities = 62/239 (25%), Positives = 100/239 (41%), Gaps = 14/239 (5%)
Query: 678 STKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELD 737
S RS + K S +E+ R + + R SA KS K E
Sbjct: 218 SRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKI 277
Query: 738 AVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSK-----KSK 792
+++ + + P+ +S+ K + +E E + S+ + K +S+
Sbjct: 278 QNNDNVGKPKSRSPSRH----KSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSR 333
Query: 793 KHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKK--SK 850
+ SRSRS S S D +KR R ESRS S S ++SERS K+ K K S
Sbjct: 334 SRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSR--SRSKSERSRKRGSKRDSKAGSS 391
Query: 851 KRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSE 909
K++ K D+ S + K+RE K + QR E + +S T +++ + S S+
Sbjct: 392 KKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQR-EGRGESENAGTNQETRSRSRSNSK 449
Score = 58.5 bits (140), Expect = 3e-08
Identities = 42/106 (39%), Positives = 51/106 (48%), Gaps = 13/106 (12%)
Query: 789 KKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKK 848
K + R SRSRS S S HS+K R RS S S S HS S RS +S+
Sbjct: 176 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGS-SKSSHSKSRSRSRSGSRSR----- 229
Query: 849 SKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKK 894
K R +S S R + KKEK R K+++R RS S KS K
Sbjct: 230 -SKSRSRSQS------RSRSKKEKSRSPSKEKSRSRSHSAGKSRSK 268
Score = 58.5 bits (140), Expect = 3e-08
Identities = 44/164 (26%), Positives = 72/164 (43%), Gaps = 10/164 (6%)
Query: 760 SERKRIF-KDFMHVLEHECQHHHSKNKKHSKKSKKHHRK-RSRSRSGSDSDDDDSHSKKK 817
S R+R + + H H K++ S SK H K RSRSRSGS S K
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRS------RSKS 232
Query: 818 RQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESE 877
R RS+SRS S+ S + +S+ H + K R KS + + D K +
Sbjct: 233 RSRSQSRSRSKKEKSRSPSKEKSRSRSH--SAGKSRSKSKDQAEEKIQNNDNVGKPKSRS 290
Query: 878 KDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRT 921
R + +S+S+ +S +++ ++ + G + + R R+
Sbjct: 291 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRS 334
Score = 54.7 bits (130), Expect = 4e-07
Identities = 51/230 (22%), Positives = 91/230 (39%), Gaps = 26/230 (11%)
Query: 681 RSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVW 740
RS + D K+ N + K ++R R K +++ R + +
Sbjct: 266 RSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQ----------------ERRV 309
Query: 741 EDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSR 800
E+ + V ++ +L R R + +K K+S++ R RSR
Sbjct: 310 EEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSR 369
Query: 801 SRS--------GSDSDDDDSHSKKKRQRSESRSASEHSS-SAESERSYKKSKKHKKKSK- 850
SRS GS D SKKK++ RS S S S ER + KS+ +++ +
Sbjct: 370 SRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRG 429
Query: 851 KRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDS 900
+ + + E+ + + K K + R+R +S SK +S K + +
Sbjct: 430 ESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSA 479
Score = 50.4 bits (119), Expect = 7e-06
Identities = 46/195 (23%), Positives = 80/195 (41%), Gaps = 4/195 (2%)
Query: 700 KAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLE 759
++ ++ER E+E+ + R S KS+ + + R R + +
Sbjct: 301 RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS 360
Query: 760 SERKRIFKDFMHVLEHECQHHHSKNKK--HSKKSKKHHRKRSRSRSGSDS-DDDDSHSKK 816
E R E + ++ K SKK KK RS+SRS S S + H+K
Sbjct: 361 REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKS 420
Query: 817 KRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRES 876
+ + E R SE++ + + RS +S K + +S S + R + K + R +
Sbjct: 421 ESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSR-SKSRSRSA 479
Query: 877 EKDRTRQRSESKHKS 891
+ +R RS S +S
Sbjct: 480 SRSPSRSRSRSHSRS 494
Score = 42.0 bits (97), Expect = 0.003
Identities = 27/110 (24%), Positives = 52/110 (47%), Gaps = 2/110 (1%)
Query: 816 KKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRE 875
+K + E + S S RS+ +S+ + S+K R +S S +S + + +
Sbjct: 168 RKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSR 227
Query: 876 SEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQ 925
S + ++R RS+S+ +S K+K+ S S S S G+ + + E+
Sbjct: 228 S-RSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSH-SAGKSRSKSKDQAEE 275
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 68.2 bits (165), Expect = 3e-11
Identities = 151/710 (21%), Positives = 274/710 (38%), Gaps = 121/710 (17%)
Query: 276 SNTVSGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTSTPAIQDQSVEVSSNTGEE 335
S T S V V + + + ++ + S + T P+ D+ E + EE
Sbjct: 289 SYTDSEEAQSVNPSSVDENIDSETEKDSLICESKQILPSKTPLPSALDE-YEFKDDDDEE 347
Query: 336 TSKQETVADFTPKKEEEESQP-AKKTYTWNTKEEAKQAFKELLKEKRVPSN---ASWEQA 391
+K K++ +E++P A+KT+ + +E+A K +K+ PS +S E +
Sbjct: 348 INKMIDDRHILRKEQRKENEPEAEKTHLFAKQEKAFYP-KSFKSKKQKPSRVLYSSTESS 406
Query: 392 MKMIINDPRYSALAKL-----SEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLEN 446
+ + + + S + + Q Y V E ++K + + K K ++ +
Sbjct: 407 DEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNKENQELK 466
Query: 447 HEK----------MTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLS--KKEKE 494
EK +T T +E+ E + S +D ++ LF +S K K
Sbjct: 467 QEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLH---LFHISTGKSPKH 523
Query: 495 QA----KQLRKRNWEALKNILDNMAN--------VTYSTTWSEAQQYLMDNPTFA----- 537
KQ E K L ++ V Y T SE +L ++ +
Sbjct: 524 SCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESE---FLPESSSVKSCKHK 580
Query: 538 ------EDEELQNMDKEDALICFEEHIRALEKEE----EEEKQKSLLRERRRQRKNRESF 587
+D L+ +K +A I E+H E + + +K+ L++ + + K RE
Sbjct: 581 EKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKE 640
Query: 588 QIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHD 647
+ + E + + S EL ++ D F DLF +E
Sbjct: 641 KHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLF-LNMEHESLTLEK 699
Query: 648 EKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEARERE 707
+ K+ K+I DK STK N K ER+
Sbjct: 700 KSKLEKNIKDDK------------------STKEKHVSKERNFK------------EERD 729
Query: 708 REKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFK 767
+ K+E+ K R+E LK+ I D K+ F + + + + I
Sbjct: 730 KIKKESEKSFREEKI--KDLKEERENIPTD-----------KDSEFTSLGMSAIEESIG- 775
Query: 768 DFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGS-DSDDDDSHSKKKRQRSESRSA 826
+H++E E K +KH K+SK+ KRS+ + + + + K+K+ + E +S
Sbjct: 776 --LHLVEKEIDIE--KQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSE 831
Query: 827 SEHSSSAESERSYKKSKK----HKKKSKKRRHKSDSP---ESDAEREKDKKEKDRESEK- 878
+ +E K+ K H +K K KS + + +REK +++ DR+ +K
Sbjct: 832 KDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKE 891
Query: 879 --DRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEG-----ELEKRRRT 921
++ R +ESK K +K K S N + S SE + EL+K+ ++
Sbjct: 892 KPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKS 941
Score = 56.6 bits (135), Expect = 1e-07
Identities = 102/444 (22%), Positives = 179/444 (40%), Gaps = 73/444 (16%)
Query: 491 KEKEQAKQLRKRNWEALKNILDNMANVTYSTTWS--EAQQYLMDNPTFAEDEELQNMDKE 548
K KE+ K+ K+ E K Y T S E Q+ + + F ++ ++ + E
Sbjct: 633 KHKEREKEKHKKEIEGEKE--------KYKTKDSAKELQRSVEFDREFWKENFFKSDETE 684
Query: 549 DALICFEEHIRALEKEEEEEK---------QKSLLRERR----RQRKNRESFQIFLDELH 595
D + E LEK+ + EK +K + +ER R + +ES + F +E
Sbjct: 685 DLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREE-- 742
Query: 596 EHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDI 655
++ + E PT D FT++ G +A +E+ + EK+I DI
Sbjct: 743 ---KIKDLKEERENIPT-DKDSEFTSL----GMSA-------IEESIGLHLVEKEI--DI 785
Query: 656 LKDKGFVVEVNTTFEDFVAI----ISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKE 711
K + + E E I I +R T IK S +K + E
Sbjct: 786 EKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSEC----- 840
Query: 712 EARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMH 771
K+K K+ + ++ E I++ +E + E + + ++++ K+ H
Sbjct: 841 -VDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKE-RH 898
Query: 772 VLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSS 831
+ E + +H K K S S+ S+S G + + D KK++ R + +S
Sbjct: 899 LAESKEKHLMEKKNKQSDNSEY-----SKSEKGKNKEKDRELDKKEKSRDKESINITNSK 953
Query: 832 SAESERSYK-----KSKKHKKKSKKRRHKSDSPESDAEREKDKKEKD------RESEKDR 880
+ E+ K++ K S K + K + ++ +EKDKK+KD R+ KD+
Sbjct: 954 HIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDK 1013
Query: 881 TRQRSESKHKS----PKKKTGKDS 900
+ S K KS PK K+ S
Sbjct: 1014 IQINSLLKLKSEADKPKPKSSPAS 1037
Score = 50.4 bits (119), Expect = 7e-06
Identities = 128/652 (19%), Positives = 253/652 (38%), Gaps = 100/652 (15%)
Query: 317 STPAIQDQSVEVSSNTGEETSKQ-------ETVADFTPKK------EEEESQPAKKTYTW 363
STP Q+ + S E S Q T ++F P+ + +E +K +
Sbjct: 532 STPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQKDFHL 591
Query: 364 NTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEK 423
E++ K+ E P+ + + +K + + + KL K++ +K + E
Sbjct: 592 EFGEKSNAKIKD---EDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEG 648
Query: 424 EEKEEARSKYKEAKESFQRFLENHEKMTSTTRYK--KAEQMFGEMEVWNAISERDRLEIY 481
E++ + K K++ + QR +E + +K + E +F ME + E+ + ++
Sbjct: 649 EKE---KYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEK-KSKLE 704
Query: 482 EDVLFFLSKKEKEQAKQ---------LRKRNW-----EALKNILDNMANVTYSTTWSEAQ 527
+++ S KEK +K+ ++K + E +K++ + N+ T +++
Sbjct: 705 KNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIP---TDKDSE 761
Query: 528 QYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNRESF 587
+ E L ++KE + E+HI+ E +E+ EK +S ++E+ ++ R++F
Sbjct: 762 FTSLGMSAIEESIGLHLVEKEIDIEKQEKHIK--ESKEKPEK-RSQIKEKDIEKMERKTF 818
Query: 588 QIFLDELHEHGQLHSMSSWMELYPTISSDIRF----TNMLGQPGSTALDLFKFYVEDLKA 643
+ HEH E I + T + G + + D +
Sbjct: 819 EKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDRE 878
Query: 644 -------RYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNS 696
R HD++K K+ ++ +K ++ N K + NS
Sbjct: 879 KSREKMDRKHDKEKPEKE-------------------RHLAESKEKHLMEKKN-KQSDNS 918
Query: 697 LLEKAEA---REREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWED---------IR 744
K+E +E++RE ++ K + KES + K + V + ++
Sbjct: 919 EYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLK 978
Query: 745 ERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSG 804
E+ EP E ++K KD E + H K + +S K + + +S
Sbjct: 979 EKTKDEPLKTPDGKEKDKKD--KDIDRYKERD--KHKDKIQINSLLKLKSEADKPKPKSS 1034
Query: 805 SDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKR-----RHKSDSP 859
S D K+ +++ E S + + KKHK+K K++ R+++
Sbjct: 1035 PASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLE 1094
Query: 860 ESDAEREKDKKEKDRESEKDRTRQRSE------SKHKSPKKKTGKDSGNWDT 905
++EK K K+ TR +S +K K PK S + DT
Sbjct: 1095 LKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSNRSQSVDT 1146
Score = 36.6 bits (83), Expect = 0.11
Identities = 23/88 (26%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 806 DSDDDDSHSKKKRQRSESRSASEHSSSAESERS-YKKSKKHKKKSKKRRHKSDSPESDAE 864
+SD D + +K R + +S + + ERS K K K K++ + SP + E
Sbjct: 14 NSDSDSNMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMKRKLPFTISPSRNEE 73
Query: 865 REKDKKEKDRESEKDRTRQRSESKHKSP 892
R+ D +++ EK +T++ + +K +P
Sbjct: 74 RDSDTEKEG--PEKKKTKKEAGNKKSTP 99
Score = 36.6 bits (83), Expect = 0.11
Identities = 36/131 (27%), Positives = 56/131 (42%), Gaps = 17/131 (12%)
Query: 810 DDSHSKKKRQRSESRSASE--HSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREK 867
DD H +K QR E+ +E H + + + Y KS K KK+ R S + SD E +
Sbjct: 353 DDRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQ 412
Query: 868 DKK------------EKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGEL 915
+KK D +++K+ E K K K+ K+ N + EL + E
Sbjct: 413 NKKISTSCSVIPETSNSDMQTKKEYV-VSGEHKQKGKVKRKLKNQ-NKNKENQELKQ-EK 469
Query: 916 EKRRRTLLEQL 926
E + T + L
Sbjct: 470 EGKENTRITNL 480
Score = 32.3 bits (72), Expect = 2.1
Identities = 55/309 (17%), Positives = 134/309 (43%), Gaps = 48/309 (15%)
Query: 283 VPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTSTPAIQDQSVEVSSNTGEETS--KQE 340
+P + E TS+ + ++ + + E++ + Q++ ++ S E+ S K++
Sbjct: 754 IPTDKDSEFTSLGMSAIEESIGLHL-VEKEIDIEK----QEKHIKESKEKPEKRSQIKEK 808
Query: 341 TVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPR 400
+ K E+E + + + K + + ++ ++ ++ S+ + E+ K
Sbjct: 809 DIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHT-EKCHKEGEKSKN 867
Query: 401 YSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAE 460
+A+ K +++++ + +KE+ E+ R E+KE + +E K + + Y K+E
Sbjct: 868 TAAIKKTDDREKSREKMDRKHDKEKPEKERH-LAESKE--KHLMEKKNKQSDNSEYSKSE 924
Query: 461 QMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYS 520
+ E+DR L KKEK + K+ N+T S
Sbjct: 925 K--------GKNKEKDR---------ELDKKEKSRDKE---------------SINITNS 952
Query: 521 TTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQ 580
E ++ + + A+ E+ ++ ++ +E ++ + +E+++K K + R + R
Sbjct: 953 KHIQEEKKSSIVDGNKAQHEKPLSLKEKTK----DEPLKTPDGKEKDKKDKDIDRYKERD 1008
Query: 581 RKNRESFQI 589
K+++ QI
Sbjct: 1009 -KHKDKIQI 1016
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 68.2 bits (165), Expect = 3e-11
Identities = 151/710 (21%), Positives = 274/710 (38%), Gaps = 121/710 (17%)
Query: 276 SNTVSGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTSTPAIQDQSVEVSSNTGEE 335
S T S V V + + + ++ + S + T P+ D+ E + EE
Sbjct: 312 SYTDSEEAQSVNPSSVDENIDSETEKDSLICESKQILPSKTPLPSALDE-YEFKDDDDEE 370
Query: 336 TSKQETVADFTPKKEEEESQP-AKKTYTWNTKEEAKQAFKELLKEKRVPSN---ASWEQA 391
+K K++ +E++P A+KT+ + +E+A K +K+ PS +S E +
Sbjct: 371 INKMIDDRHILRKEQRKENEPEAEKTHLFAKQEKAFYP-KSFKSKKQKPSRVLYSSTESS 429
Query: 392 MKMIINDPRYSALAKL-----SEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLEN 446
+ + + + S + + Q Y V E ++K + + K K ++ +
Sbjct: 430 DEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNKENQELK 489
Query: 447 HEK----------MTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLS--KKEKE 494
EK +T T +E+ E + S +D ++ LF +S K K
Sbjct: 490 QEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLH---LFHISTGKSPKH 546
Query: 495 QA----KQLRKRNWEALKNILDNMAN--------VTYSTTWSEAQQYLMDNPTFA----- 537
KQ E K L ++ V Y T SE +L ++ +
Sbjct: 547 SCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESE---FLPESSSVKSCKHK 603
Query: 538 ------EDEELQNMDKEDALICFEEHIRALEKEE----EEEKQKSLLRERRRQRKNRESF 587
+D L+ +K +A I E+H E + + +K+ L++ + + K RE
Sbjct: 604 EKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKE 663
Query: 588 QIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHD 647
+ + E + + S EL ++ D F DLF +E
Sbjct: 664 KHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLF-LNMEHESLTLEK 722
Query: 648 EKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEARERE 707
+ K+ K+I DK STK N K ER+
Sbjct: 723 KSKLEKNIKDDK------------------STKEKHVSKERNFK------------EERD 752
Query: 708 REKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFK 767
+ K+E+ K R+E LK+ I D K+ F + + + + I
Sbjct: 753 KIKKESEKSFREEKI--KDLKEERENIPTD-----------KDSEFTSLGMSAIEESIG- 798
Query: 768 DFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGS-DSDDDDSHSKKKRQRSESRSA 826
+H++E E K +KH K+SK+ KRS+ + + + + K+K+ + E +S
Sbjct: 799 --LHLVEKEIDIE--KQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSE 854
Query: 827 SEHSSSAESERSYKKSKK----HKKKSKKRRHKSDSP---ESDAEREKDKKEKDRESEK- 878
+ +E K+ K H +K K KS + + +REK +++ DR+ +K
Sbjct: 855 KDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKE 914
Query: 879 --DRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEG-----ELEKRRRT 921
++ R +ESK K +K K S N + S SE + EL+K+ ++
Sbjct: 915 KPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKS 964
Score = 56.6 bits (135), Expect = 1e-07
Identities = 102/444 (22%), Positives = 179/444 (40%), Gaps = 73/444 (16%)
Query: 491 KEKEQAKQLRKRNWEALKNILDNMANVTYSTTWS--EAQQYLMDNPTFAEDEELQNMDKE 548
K KE+ K+ K+ E K Y T S E Q+ + + F ++ ++ + E
Sbjct: 656 KHKEREKEKHKKEIEGEKE--------KYKTKDSAKELQRSVEFDREFWKENFFKSDETE 707
Query: 549 DALICFEEHIRALEKEEEEEK---------QKSLLRERR----RQRKNRESFQIFLDELH 595
D + E LEK+ + EK +K + +ER R + +ES + F +E
Sbjct: 708 DLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREE-- 765
Query: 596 EHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDI 655
++ + E PT D FT++ G +A +E+ + EK+I DI
Sbjct: 766 ---KIKDLKEERENIPT-DKDSEFTSL----GMSA-------IEESIGLHLVEKEI--DI 808
Query: 656 LKDKGFVVEVNTTFEDFVAI----ISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKE 711
K + + E E I I +R T IK S +K + E
Sbjct: 809 EKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSEC----- 863
Query: 712 EARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMH 771
K+K K+ + ++ E I++ +E + E + + ++++ K+ H
Sbjct: 864 -VDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKE-RH 921
Query: 772 VLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSS 831
+ E + +H K K S S+ S+S G + + D KK++ R + +S
Sbjct: 922 LAESKEKHLMEKKNKQSDNSEY-----SKSEKGKNKEKDRELDKKEKSRDKESINITNSK 976
Query: 832 SAESERSYK-----KSKKHKKKSKKRRHKSDSPESDAEREKDKKEKD------RESEKDR 880
+ E+ K++ K S K + K + ++ +EKDKK+KD R+ KD+
Sbjct: 977 HIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDK 1036
Query: 881 TRQRSESKHKS----PKKKTGKDS 900
+ S K KS PK K+ S
Sbjct: 1037 IQINSLLKLKSEADKPKPKSSPAS 1060
Score = 50.4 bits (119), Expect = 7e-06
Identities = 128/652 (19%), Positives = 253/652 (38%), Gaps = 100/652 (15%)
Query: 317 STPAIQDQSVEVSSNTGEETSKQ-------ETVADFTPKK------EEEESQPAKKTYTW 363
STP Q+ + S E S Q T ++F P+ + +E +K +
Sbjct: 555 STPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQKDFHL 614
Query: 364 NTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEK 423
E++ K+ E P+ + + +K + + + KL K++ +K + E
Sbjct: 615 EFGEKSNAKIKD---EDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEG 671
Query: 424 EEKEEARSKYKEAKESFQRFLENHEKMTSTTRYK--KAEQMFGEMEVWNAISERDRLEIY 481
E++ + K K++ + QR +E + +K + E +F ME + E+ + ++
Sbjct: 672 EKE---KYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEK-KSKLE 727
Query: 482 EDVLFFLSKKEKEQAKQ---------LRKRNW-----EALKNILDNMANVTYSTTWSEAQ 527
+++ S KEK +K+ ++K + E +K++ + N+ T +++
Sbjct: 728 KNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIP---TDKDSE 784
Query: 528 QYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKNRESF 587
+ E L ++KE + E+HI+ E +E+ EK +S ++E+ ++ R++F
Sbjct: 785 FTSLGMSAIEESIGLHLVEKEIDIEKQEKHIK--ESKEKPEK-RSQIKEKDIEKMERKTF 841
Query: 588 QIFLDELHEHGQLHSMSSWMELYPTISSDIRF----TNMLGQPGSTALDLFKFYVEDLKA 643
+ HEH E I + T + G + + D +
Sbjct: 842 EKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDRE 901
Query: 644 -------RYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNS 696
R HD++K K+ ++ +K ++ N K + NS
Sbjct: 902 KSREKMDRKHDKEKPEKE-------------------RHLAESKEKHLMEKKN-KQSDNS 941
Query: 697 LLEKAEA---REREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWED---------IR 744
K+E +E++RE ++ K + KES + K + V + ++
Sbjct: 942 EYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLK 1001
Query: 745 ERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSG 804
E+ EP E ++K KD E + H K + +S K + + +S
Sbjct: 1002 EKTKDEPLKTPDGKEKDKKD--KDIDRYKERD--KHKDKIQINSLLKLKSEADKPKPKSS 1057
Query: 805 SDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKR-----RHKSDSP 859
S D K+ +++ E S + + KKHK+K K++ R+++
Sbjct: 1058 PASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLE 1117
Query: 860 ESDAEREKDKKEKDRESEKDRTRQRSE------SKHKSPKKKTGKDSGNWDT 905
++EK K K+ TR +S +K K PK S + DT
Sbjct: 1118 LKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSNRSQSVDT 1169
Score = 38.9 bits (89), Expect = 0.022
Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 9/130 (6%)
Query: 806 DSDDDDSHSKKKRQRSESRSASEHSSSAESERS-YKKSKKHKKKSKKRRHKSDSPESDAE 864
+SD D + +K R + +S + + ERS K K K K++ + SP + E
Sbjct: 14 NSDSDSNMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMKRKLPFTISPSRNEE 73
Query: 865 REKDKKE-----KDRESEKDRTRQRSESKHKSP-KKKTGKDSGNWDTSGSELSEGE--LE 916
R+ D + E+ + R+ S+ + P KKKT K++GN ++ + G E
Sbjct: 74 RDSDTDSDPGHTSENWGERLISSYRTYSEKEGPEKKKTKKEAGNKKSTPVSILFGYPLSE 133
Query: 917 KRRRTLLEQL 926
+++ LL Q+
Sbjct: 134 RKQMALLMQM 143
Score = 36.6 bits (83), Expect = 0.11
Identities = 36/131 (27%), Positives = 56/131 (42%), Gaps = 17/131 (12%)
Query: 810 DDSHSKKKRQRSESRSASE--HSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREK 867
DD H +K QR E+ +E H + + + Y KS K KK+ R S + SD E +
Sbjct: 376 DDRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQ 435
Query: 868 DKK------------EKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGEL 915
+KK D +++K+ E K K K+ K+ N + EL + E
Sbjct: 436 NKKISTSCSVIPETSNSDMQTKKEYV-VSGEHKQKGKVKRKLKNQ-NKNKENQELKQ-EK 492
Query: 916 EKRRRTLLEQL 926
E + T + L
Sbjct: 493 EGKENTRITNL 503
Score = 32.3 bits (72), Expect = 2.1
Identities = 55/309 (17%), Positives = 134/309 (43%), Gaps = 48/309 (15%)
Query: 283 VPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTSTPAIQDQSVEVSSNTGEETS--KQE 340
+P + E TS+ + ++ + + E++ + Q++ ++ S E+ S K++
Sbjct: 777 IPTDKDSEFTSLGMSAIEESIGLHL-VEKEIDIEK----QEKHIKESKEKPEKRSQIKEK 831
Query: 341 TVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPR 400
+ K E+E + + + K + + ++ ++ ++ S+ + E+ K
Sbjct: 832 DIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHT-EKCHKEGEKSKN 890
Query: 401 YSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAE 460
+A+ K +++++ + +KE+ E+ R E+KE + +E K + + Y K+E
Sbjct: 891 TAAIKKTDDREKSREKMDRKHDKEKPEKERH-LAESKE--KHLMEKKNKQSDNSEYSKSE 947
Query: 461 QMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYS 520
+ E+DR L KKEK + K+ N+T S
Sbjct: 948 K--------GKNKEKDR---------ELDKKEKSRDKE---------------SINITNS 975
Query: 521 TTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQ 580
E ++ + + A+ E+ ++ ++ +E ++ + +E+++K K + R + R
Sbjct: 976 KHIQEEKKSSIVDGNKAQHEKPLSLKEKTK----DEPLKTPDGKEKDKKDKDIDRYKERD 1031
Query: 581 RKNRESFQI 589
K+++ QI
Sbjct: 1032 -KHKDKIQI 1039
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 68.2 bits (165), Expect = 3e-11
Identities = 52/220 (23%), Positives = 94/220 (42%), Gaps = 5/220 (2%)
Query: 699 EKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITL 758
E+ RER+RE+E+ R+++R+ + + ++ E D + RER + D
Sbjct: 690 ERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRER--ERERERDREK 747
Query: 759 ESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKR 818
E ER+R ++ E E + + ++ +++ K R+R R D DD K++
Sbjct: 748 EREREREERERERERERERERERERERERARERDKE-RERQRDWEDKDKGRDDRREKREE 806
Query: 819 QRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEK 878
R E R+ + +S++ Y+ + +R + SP+SDA D K +
Sbjct: 807 IR-EDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLS 865
Query: 879 DRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKR 918
R + ES+ SP T G W + E +R
Sbjct: 866 QVVRPQ-ESRSLSPSHLTEDRQGRWKEEDRKPERKESSRR 904
Score = 54.3 bits (129), Expect = 5e-07
Identities = 42/201 (20%), Positives = 90/201 (44%), Gaps = 8/201 (3%)
Query: 702 EAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVK--EPAFEDITLE 759
E R ER++ + R+ ++ S S ++ EL+ E ER V + ++ E
Sbjct: 623 ERRHGERDRRDNRERDQRPS---SPIRHQGRNDELERD-ERREERRVDRVDDRRDERARE 678
Query: 760 SERKRIFKDFMHVLEHECQHHHSKNKKHS-KKSKKHHRKRSRSRSGSDSDDDDSHSKKKR 818
+R+R +D E E + + K+ ++ + R+R R + D D ++R
Sbjct: 679 RDRERE-RDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRER 737
Query: 819 QRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEK 878
+R R + ER ++ ++ +++ ++ R + + E D ERE+ + +D++ +
Sbjct: 738 ERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGR 797
Query: 879 DRTRQRSESKHKSPKKKTGKD 899
D R++ E + + G D
Sbjct: 798 DDRREKREEIREDRNPRDGHD 818
Score = 54.3 bits (129), Expect = 5e-07
Identities = 47/219 (21%), Positives = 95/219 (43%), Gaps = 24/219 (10%)
Query: 702 EAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESE 761
+ R E E++E R+ +R + ++A E D E RER E E
Sbjct: 648 QGRNDELERDERREERRVDRVDDRRDERAR---ERDRERERDRER------------ERE 692
Query: 762 RKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRS 821
R+R +D E E + ++ ++ ++ K+ R+R R R D D +++R+R
Sbjct: 693 RERE-RDREREKERELERERARERERERE-KERDRERDRDR------DHDRERERERERD 744
Query: 822 ESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRT 881
+ E ER ++ ++ +++ ++ R + E + +R+ + K+K R+ +++
Sbjct: 745 REKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKR 804
Query: 882 RQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRR 920
+ E ++ K + GS S + KRRR
Sbjct: 805 EEIREDRNPRDGHDERKSKKRYRNEGSP-SPRQSPKRRR 842
Score = 49.7 bits (117), Expect = 1e-05
Identities = 28/144 (19%), Positives = 70/144 (48%), Gaps = 6/144 (4%)
Query: 782 SKNKKHSKKSKKHHRKRSRSRSG-----SDSDDDDSHSKKKRQRSESRSASEHSSSAESE 836
S ++H ++ ++ +R+R + S +D+ + +++ +R + + E +
Sbjct: 621 SFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERD 680
Query: 837 RSYKKSKKHKKKSKKRRHKSDSPESDAEREKDK-KEKDRESEKDRTRQRSESKHKSPKKK 895
R ++ ++ +++ ++ R + E + ERE+ + +E++RE E+DR R R + +++
Sbjct: 681 RERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERE 740
Query: 896 TGKDSGNWDTSGSELSEGELEKRR 919
+D E E E E+ R
Sbjct: 741 RERDREKEREREREERERERERER 764
Score = 48.1 bits (113), Expect = 4e-05
Identities = 29/153 (18%), Positives = 69/153 (45%), Gaps = 10/153 (6%)
Query: 780 HHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSY 839
H +N + + ++ R+ R D D+ ++ R+R R E E +R
Sbjct: 647 HQGRNDELERDERREERRVDRV----DDRRDERARERDRERERDRER-ERERERERDRER 701
Query: 840 KKSKKHKKKSKKRRHKSDSPESDAEREKDK-----KEKDRESEKDRTRQRSESKHKSPKK 894
+K ++ +++ + R + E D ER++D+ +E++RE ++++ R+R + + ++
Sbjct: 702 EKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERE 761
Query: 895 KTGKDSGNWDTSGSELSEGELEKRRRTLLEQLD 927
+ + + E + E+ R+ E D
Sbjct: 762 RERERERERERERERARERDKERERQRDWEDKD 794
Score = 46.6 bits (109), Expect = 1e-04
Identities = 53/225 (23%), Positives = 98/225 (43%), Gaps = 23/225 (10%)
Query: 699 EKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITL 758
E+ ARER++E+E R + K+ + ++ I D D + + + +
Sbjct: 773 ERERARERDKERERQRDWEDKDKG-RDDRREKREEIREDRNPRDGHDERKSKKRYRNEGS 831
Query: 759 ESERKRIFKDFMHVLEHECQHH-HSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKK 817
S R+ + H + + + KN+KH S+ + SRS S S +D K+
Sbjct: 832 PSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKE 891
Query: 818 RQRSESRSASEHSSSAESERSYKKSKKHKKKSK--KRRHKSDSPESDAEREKD----KKE 871
R R ES R Y++ + +K S K+R +++ ES R +D +
Sbjct: 892 EDRKPERK--------ESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQS 943
Query: 872 KDRESE---KDRTRQRSESKHKSPKKK----TGKDSGNWDTSGSE 909
+DRE+ D +++++ + K KKK G + GN +T+ +
Sbjct: 944 EDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSED 988
Score = 45.4 bits (106), Expect = 2e-04
Identities = 30/143 (20%), Positives = 56/143 (39%), Gaps = 9/143 (6%)
Query: 781 HSKNKKHSKKSKKHHRKRSRSRSGSDSD-DDDSHSKKKRQRSESRSASEHSSSAESERSY 839
HS + K+S HR R + D + SH ++ +R ++R + + ER Y
Sbjct: 377 HSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREY 436
Query: 840 KKSKKHKKKSKKRRHKSDSPE-SDAEREKDKKE-------KDRESEKDRTRQRSESKHKS 891
++ + + + R D + DA +D++E +D +D +R ES+
Sbjct: 437 EQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPR 496
Query: 892 PKKKTGKDSGNWDTSGSELSEGE 914
+ T D G + E
Sbjct: 497 DSRSTRDAHDYRDREGRDTHRKE 519
Score = 45.1 bits (105), Expect = 3e-04
Identities = 25/113 (22%), Positives = 54/113 (47%), Gaps = 2/113 (1%)
Query: 779 HHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERS 838
+H S + S + + +R DS + H ++ R+ + R S R+
Sbjct: 592 YHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRN 651
Query: 839 YKKSKKHKKKSKKRRHKSDSPESDAEREKDK-KEKDRESEKDRTRQRSESKHK 890
+ ++ +++ ++R + D + RE+D+ +E+DRE E++R R+R + K
Sbjct: 652 -DELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREK 703
Score = 45.1 bits (105), Expect = 3e-04
Identities = 36/144 (25%), Positives = 63/144 (43%), Gaps = 11/144 (7%)
Query: 759 ESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKR---SRSRSGSDSDDDDSHSK 815
+S RKR+ +H + + S +KS+ KR SRS S SD D SHS
Sbjct: 1221 QSGRKRV----LHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTS-SDRQDSRSHSS 1275
Query: 816 KKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRE 875
++ R S S +S ++ +++ ++ R + D+ + + +R+ DK D
Sbjct: 1276 RRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADK---DWP 1332
Query: 876 SEKDRTRQRSESKHKSPKKKTGKD 899
+DR R R + + K+ D
Sbjct: 1333 RNRDRDRLRERERERERDKRRDLD 1356
Score = 45.1 bits (105), Expect = 3e-04
Identities = 37/171 (21%), Positives = 70/171 (40%), Gaps = 28/171 (16%)
Query: 788 SKKSKKHHRKRSRSRSGSDSDDD-----DSHSKKKRQRSESRSASEHSSSAESERSYKKS 842
S++S ++ SRSGS D D + + + E R + ++++ + ++
Sbjct: 1275 SRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRN 1334
Query: 843 KKHKKKSKKRRHKSDSPESDAEREK-----DKKEKDRESEKDRTRQRS------------ 885
+ + ++ R + D +RE+ D E+DR+ ++DRT + S
Sbjct: 1335 RDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKL 1394
Query: 886 ESKHKSPKKKTGKDSGNWDTS------GSELSEGELEKRRRTLLEQLDDDQ 930
E +H+ + T +DS D GS E K RT + DD+
Sbjct: 1395 EGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDE 1445
Score = 43.9 bits (102), Expect = 7e-04
Identities = 59/242 (24%), Positives = 96/242 (39%), Gaps = 53/242 (21%)
Query: 700 KAEAREREREKEEARKMKRKESAFKSML-------------------KQAAPPIELD-AV 739
K+ R+ + A K RK SA S L PPI D A+
Sbjct: 217 KSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIAL 276
Query: 740 WEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSK--NKKHSKKSKKHHRK 797
+ +E++ + E+ T + + + +DF E + + + HS S +HH
Sbjct: 277 GKKYKEKYKVKDRIEEKTRDGKDRG--RDFERQREKRDKPRSTSPAGQHHSPISSRHHS- 333
Query: 798 RSRSRSGSDSDDDDSHSKKKRQRSES----------RSASEHSSSAESERSYKKS-KKHK 846
S S+SGS ++KR S S RSAS + S + S K+S +H+
Sbjct: 334 -SSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHR 392
Query: 847 --------------KKSKKRRH-KSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKS 891
+S RRH + + +REKD +E +RE E+D++ R +
Sbjct: 393 SPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSRE-EREYEQDQSSSRDHRDDRE 451
Query: 892 PK 893
P+
Sbjct: 452 PR 453
Score = 43.5 bits (101), Expect = 0.001
Identities = 64/285 (22%), Positives = 115/285 (40%), Gaps = 45/285 (15%)
Query: 677 SSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFK--------SMLK 728
S+ +RS G+++ + + + ++R EE+ RKES+ + K
Sbjct: 72 SNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITK 131
Query: 729 QAAPPIELDAV-WEDIRERF----VKEPAFEDITLESERKRIFKDFMHVLEHECQHHH-- 781
+ P E + V WE R+ + +++LE +R++I ++ M + + +
Sbjct: 132 ERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEI 191
Query: 782 ------SKNKKHSKKSKKHH-RKRSRSRSGSDSDDDDSHSKKKRQRSE-SRSASEHSSSA 833
S SK S RK S+S S S SKK R+ S S + ++
Sbjct: 192 IIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNS 251
Query: 834 ESERSYKKS-----------------KKHKKKSKKRRHKSDSPESDAEREKDKKEKDRES 876
++ +S KK KK+K+K K + + +R +D E+ RE
Sbjct: 252 KTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRD-FERQRE- 309
Query: 877 EKDRTRQRSES-KHKSPKKKTGKDSGNWDTSGSELSEGELEKRRR 920
++D+ R S + +H SP S + SGS + RR+
Sbjct: 310 KRDKPRSTSPAGQHHSPISSRHHSSSS--QSGSSIQRHSPSPRRK 352
Score = 42.4 bits (98), Expect = 0.002
Identities = 33/145 (22%), Positives = 62/145 (42%), Gaps = 13/145 (8%)
Query: 781 HSKNKKH----SKKSKKHHRKRSRSRSGSDSDDDDSHSKK--KRQRSESRSASEHSSSAE 834
HS N + +S R R R D D S ++ +R R ++R + SS
Sbjct: 586 HSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPI 645
Query: 835 SERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKK 894
+ + ++ ++RR D R++ +E+DRE E+DR R+R + + ++
Sbjct: 646 RHQGRNDELERDERREERR----VDRVDDRRDERARERDRERERDRERERERERERDRER 701
Query: 895 KTGKDSGNWDTSGSELSEGELEKRR 919
+ ++ + + E E EK R
Sbjct: 702 EKERE---LERERAREREREREKER 723
Score = 42.0 bits (97), Expect = 0.003
Identities = 34/142 (23%), Positives = 61/142 (42%), Gaps = 5/142 (3%)
Query: 780 HHSKNKKHSKKSKKHH--RKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESER 837
H S + + +K H R R +++S + + S + ++ SRS S + S
Sbjct: 1215 HRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHS 1274
Query: 838 SYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTG 897
S + S + ++ R DS + ER++ + +++RE E+ TRQR +
Sbjct: 1275 SRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRN 1334
Query: 898 KDSGNWDTSGSELSEGELEKRR 919
+D D E E +KRR
Sbjct: 1335 RDR---DRLRERERERERDKRR 1353
Score = 40.4 bits (93), Expect = 0.008
Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 9/123 (7%)
Query: 785 KKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRS-ASEHSS------SAESER 837
KK+ +K K R ++R G D D ++KR + S S A +H S + S +
Sbjct: 278 KKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQ 337
Query: 838 SYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSES--KHKSPKKK 895
S ++H +++R S S + + S + QR +S +H+SP ++
Sbjct: 338 SGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMRE 397
Query: 896 TGK 898
G+
Sbjct: 398 KGR 400
Score = 39.3 bits (90), Expect = 0.017
Identities = 40/168 (23%), Positives = 73/168 (43%), Gaps = 30/168 (17%)
Query: 708 REKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFK 767
R KEE RK +RKES+ + E+ +KE + + E+ I +
Sbjct: 888 RWKEEDRKPERKESSRR------------------YEEQELKEKV-SSVDKQREQTEILE 928
Query: 768 DFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSAS 827
+ HH S++++ S ++ ++K+++ + KKK++
Sbjct: 929 SSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQK--------KPIKKKKEDDVGIERG 980
Query: 828 EHSSSAESERSYKKSKKHKKKS-KKRRHKS--DSPESDAEREKDKKEK 872
+++E + + K KKKS +K+R KS DS SD E + K+K
Sbjct: 981 NIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKK 1028
Score = 38.1 bits (87), Expect = 0.038
Identities = 52/267 (19%), Positives = 104/267 (38%), Gaps = 62/267 (23%)
Query: 704 REREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERK 763
R+RE++ E R+ ++ +S+ + P D R+R + L R
Sbjct: 424 RDREKDSREEREYEQDQSSSRDHRDDREP--------RDGRDRRDARDTRDRRELRDSRD 475
Query: 764 RIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDD----------SH 813
+D + ++ S++ + S+ ++ H R R + +D +H
Sbjct: 476 --MRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNH 533
Query: 814 SKKKRQRSESRSASEHSSSAESERSY------------KKSKKHKKKSKKRRHKSDS--- 858
+++ R+E R+ S + S +E +K + + S+ H S+S
Sbjct: 534 LREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYH 593
Query: 859 ---------PESDAEREKDKKEKDRES-------EKDRTRQRS-ESKHKSPKKKTGKDSG 901
PE D E+D +++ R+S E+DR R + + SP + G++
Sbjct: 594 DSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRN-- 651
Query: 902 NWDTSGSELSEGELEKRRRTLLEQLDD 928
EL E + RR ++++DD
Sbjct: 652 ------DELERDERREERR--VDRVDD 670
Score = 37.0 bits (84), Expect = 0.085
Identities = 42/170 (24%), Positives = 65/170 (38%), Gaps = 18/170 (10%)
Query: 752 AFEDITLESERKRIFK-DFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDD 810
A ED + R R+ K + HV + QH ++K S + RS + S +
Sbjct: 1152 ANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSN 1211
Query: 811 DSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKK 870
DS + +S R HS S + E++ ++KS+ + K P
Sbjct: 1212 DSAHRSGDDQS-GRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPS---------- 1260
Query: 871 EKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRR 920
R + DR RS S +S + D SGS S L++R R
Sbjct: 1261 ---RSTSSDRQDSRSHSSRRSSPES---DRQVHSRSGSFDSRDRLQERDR 1304
Score = 32.3 bits (72), Expect = 2.1
Identities = 50/251 (19%), Positives = 101/251 (40%), Gaps = 34/251 (13%)
Query: 217 ESSKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANA---ST 273
E+ TT + P P + + +A A A AA AAAA + + +A ST
Sbjct: 1080 EAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITIST 1139
Query: 274 SA--SNTVSGT--------------VPVVPEPEVTSIVA---TVVDNENTVTISTEEQAQ 314
SA +NT + T V V P VT A +D + + ++ + +
Sbjct: 1140 SATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNR 1199
Query: 315 LTSTPAIQDQSVEVSSNTGEETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFK 374
++ ++ S + + +G++ S ++ V S+ +KT + E K
Sbjct: 1200 SHTSGRLRSPSNDSAHRSGDDQSGRKRVL-------HSGSRDREKTKSLEITGERKSRID 1252
Query: 375 ELLKEKRVPSNASWEQAMKMIINDPRYSAL---AKLSEKKQAFNAYKVQTEKEEKEEARS 431
+L ++ PS ++ + R S+ ++ + +F++ E++ E R
Sbjct: 1253 QL--KRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRE 1310
Query: 432 KYKEAKESFQR 442
+ +E +++ QR
Sbjct: 1311 RERERRDTRQR 1321
Score = 32.3 bits (72), Expect = 2.1
Identities = 52/234 (22%), Positives = 77/234 (32%), Gaps = 60/234 (25%)
Query: 704 REREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERK 763
RERERE+ + R+ + A D W R+R D E ER+
Sbjct: 1309 RERERERRDTRQREWDRDA--------------DKDWPRNRDR--------DRLRERERE 1346
Query: 764 RIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKR----Q 819
R ++ K+ R R R SDS + D + R
Sbjct: 1347 R------------------------ERDKRRDLDRERERLISDSVERDRDRDRDRTFESS 1382
Query: 820 RSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKD 879
+ ES E E ER + + + K R D E +K E+ E
Sbjct: 1383 QIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAG 1442
Query: 880 RTRQRSESKHKSPKKKTGKDSGNWDTSGSELSE---GELEKRRRTLLEQLDDDQ 930
+ + H +G G S EL E G+ EKR +Q D+++
Sbjct: 1443 DDESKLDDAH---SLGSGAGEGYEPISDDELDEILAGDAEKRE----DQQDEEK 1489
Score = 31.2 bits (69), Expect = 4.7
Identities = 16/44 (36%), Positives = 24/44 (54%)
Query: 539 DEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRK 582
DE + D+E E R E++ E EK++ L RER R+R+
Sbjct: 673 DERARERDRERERDRERERERERERDREREKERELERERARERE 716
Score = 30.8 bits (68), Expect = 6.1
Identities = 39/176 (22%), Positives = 75/176 (42%), Gaps = 24/176 (13%)
Query: 699 EKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITL 758
++ RERERE+++ R + R+ S D+V D R+R ++ FE +
Sbjct: 1338 DRLRERERERERDKRRDLDRERERLIS-----------DSVERD-RDR-DRDRTFESSQI 1384
Query: 759 ESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKR 818
ES ++ K LE E H + S+ S ++R GS ++++ K
Sbjct: 1385 ESVKRCEAK-----LEGE---HERDLESTSRDSLALDKERMDKDLGSVQGFEETN---KS 1433
Query: 819 QRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDR 874
+R+ES A + S + S + + DAE+ +D++++++
Sbjct: 1434 ERTESLEAGDDESKLDDAHSLGSGAGEGYEPISDDELDEILAGDAEKREDQQDEEK 1489
>gi|116812577 LUC7-like 2 [Homo sapiens]
Length = 392
Score = 67.0 bits (162), Expect = 8e-11
Identities = 61/249 (24%), Positives = 104/249 (41%), Gaps = 42/249 (16%)
Query: 688 GNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPI------------- 734
GN++ + + E +AR ++RE EE + S+F+ +
Sbjct: 147 GNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRL 206
Query: 735 ------ELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHH-------- 780
+L + +IRE+ + + + E + KR + E E +
Sbjct: 207 ADHFGGKLHLGFIEIREKLEE---LKRVVAEKQEKRNQERLKRREEREREEREKLRRSRS 263
Query: 781 HSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSAS-----EHSSSAES 835
HSKN K S +S++H R RSRS S S S++KR R SRS+S H S S
Sbjct: 264 HSKNPKRS-RSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHS 322
Query: 836 ERSYKKSKKHKKKSKKRRHKSDSPESDAERE------KDKKEKDRESEKDRTRQRSESKH 889
R + + ++ SK+R D D +R +D+ KD++ + RSE +
Sbjct: 323 SRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRR 382
Query: 890 KSPKKKTGK 898
S +++ G+
Sbjct: 383 SSEEREAGE 391
Score = 38.1 bits (87), Expect = 0.038
Identities = 28/121 (23%), Positives = 52/121 (42%), Gaps = 5/121 (4%)
Query: 814 SKKKRQRSESRSASEHSSSAESERSYKKSKKHKK---KSKKRRHKSDSPES-DAEREKDK 869
++K+ +R++ R E ++S+ H K +S+ R H+ S ER++
Sbjct: 233 AEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRT 292
Query: 870 KEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDD 929
+ K RE ++ R R RS S+ +S + + S + E+ R L D D
Sbjct: 293 RSKSRE-KRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRD 351
Query: 930 Q 930
+
Sbjct: 352 R 352
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 65.9 bits (159), Expect = 2e-10
Identities = 56/209 (26%), Positives = 89/209 (42%), Gaps = 20/209 (9%)
Query: 699 EKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITL 758
E E ERE E + RK+ ++ +A P + ED +E ED++
Sbjct: 110 ENVEYIEREESDGEYDEFGRKKKKYRG---KAVGPASILKEVEDKESEGEEEDEDEDLSK 166
Query: 759 ESERKRIFKDFMHVLEH--ECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKK 816
+ +D + ++ + NKK S + + + S SRS S S S +
Sbjct: 167 YKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSR 226
Query: 817 KRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHK-------------SDSPESDA 863
R RS S S+S+ S S S R +S+ K +S R H+ S SPE +
Sbjct: 227 SRSRSRSSSSSQ-SRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNR 285
Query: 864 EREKDKKEKDRESEKDRTRQRS-ESKHKS 891
+R + + + +K RTR RS E +H+S
Sbjct: 286 KRSRSRSSSSGDRKKRRTRSRSPERRHRS 314
Score = 52.8 bits (125), Expect = 2e-06
Identities = 36/117 (30%), Positives = 54/117 (46%), Gaps = 3/117 (2%)
Query: 807 SDDDDSHSKK--KRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAE 864
S+++DS+ KK +R RS+SRS+ SSS S S +S+ + +S S S E
Sbjct: 188 SEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRE 247
Query: 865 REKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRT 921
R + + K R S + R S + +S + N S S S K+RRT
Sbjct: 248 RSRSRGSKSRSSSRSH-RGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRT 303
Score = 40.8 bits (94), Expect = 0.006
Identities = 29/125 (23%), Positives = 51/125 (40%), Gaps = 8/125 (6%)
Query: 801 SRSGSDSDDDDSHSKKKRQRSESRSASEHS----SSAESERSYKKSKKHKKKSKKRRHKS 856
S + +D+D SK K E ++ S ++E E S KK + +SK R S
Sbjct: 153 SEGEEEDEDEDL-SKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSR---S 208
Query: 857 DSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELE 916
S + + R + R+ S+S+ +S ++ + G+ S S G
Sbjct: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSS 268
Query: 917 KRRRT 921
R+R+
Sbjct: 269 PRKRS 273
Score = 32.0 bits (71), Expect = 2.7
Identities = 22/121 (18%), Positives = 55/121 (45%), Gaps = 2/121 (1%)
Query: 319 PAIQDQSVEVSSNTGEETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLK 378
PA + VE + GEE + E ++ + ++E+E Y + EE K+ +
Sbjct: 141 PASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNR 200
Query: 379 EKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKE 438
R S +S ++ + S+ ++ + ++ ++ + ++ +E +RS+ +++
Sbjct: 201 RSRSKSRSSHSRSSSR--SSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRS 258
Query: 439 S 439
S
Sbjct: 259 S 259
>gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo
sapiens]
Length = 558
Score = 65.9 bits (159), Expect = 2e-10
Identities = 53/218 (24%), Positives = 94/218 (43%), Gaps = 23/218 (10%)
Query: 700 KAEARE-REREKEEARKMKRKESAFKSMLKQAAPPIELDAVWE-------DIRERFVKEP 751
K RE R KEE + E + K+ + Q ++ D E D + +
Sbjct: 199 KCSFREARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADD 258
Query: 752 AFEDITLESERKRIFK----DFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDS 807
E+ + R+++ + DF H H Q+H + S +HH K SR+ G +
Sbjct: 259 EIEETRVNCRREKVIETPENDFKH---HRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEK 315
Query: 808 DDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREK 867
+D K+ R + + ++ +S R + S H+ KR + D P + +RE+
Sbjct: 316 REDQHQQKQSRDQENHYTDRDYRKERDSHRHREAS--HRDSHWKRHEQEDKPRARDQRER 373
Query: 868 D----KKEKDRE--SEKDRTRQRSESKHKSPKKKTGKD 899
K+EKDRE S++++ R R ++ P +K K+
Sbjct: 374 SDRVWKREKDREKYSQREQERDRQQNDQNRPSEKGEKE 411
Score = 48.9 bits (115), Expect = 2e-05
Identities = 35/158 (22%), Positives = 72/158 (45%), Gaps = 25/158 (15%)
Query: 780 HHSKNKK----HSKKSKKHHRKRSRSRSGSDSDDD----------------DSHSKKKRQ 819
HH+K + H K+ +H +K+SR + +D D DSH K+ Q
Sbjct: 302 HHTKGSRTSRGHEKREDQHQQKQSRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQ 361
Query: 820 RSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESE-K 878
+ R+ + S+R +K+ K +K S++ + + D ++D R +K EK+ +S+ K
Sbjct: 362 EDKPRARDQRE---RSDRVWKREKDREKYSQREQER-DRQQNDQNRPSEKGEKEEKSKAK 417
Query: 879 DRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELE 916
+ + + ++++ K ++ SE ++ E
Sbjct: 418 EEHMKVRKERYENNDKYRDREKREVGVQSSERNQDRKE 455
Score = 43.5 bits (101), Expect = 0.001
Identities = 36/147 (24%), Positives = 68/147 (46%), Gaps = 22/147 (14%)
Query: 776 ECQHHHSKNKKHSKKSKKHHR-KRSRS-RSGSDSDDDDSHSKKKRQRSESRSASEH-SSS 832
E H S K+H ++ K R +R RS R D + +S+++++R ++ S
Sbjct: 348 EASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDREKYSQREQERDRQQNDQNRPSEK 407
Query: 833 AESERSYKKSKKHKKKSKKR---------RHKSDSPESDAEREKDKKE-------KDRES 876
E E K ++H K K+R R K + +ER +D+KE KD+
Sbjct: 408 GEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGVQSSERNQDRKESSPNSRAKDKFL 467
Query: 877 EKDRT---RQRSESKHKSPKKKTGKDS 900
+++R+ R ++ K ++ +K + +S
Sbjct: 468 DQERSNKMRNMAKDKERNQEKPSNSES 494
Score = 42.0 bits (97), Expect = 0.003
Identities = 29/126 (23%), Positives = 59/126 (46%), Gaps = 23/126 (18%)
Query: 778 QHHHSKNKKHSKKSKKH-HRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESE 836
Q +H ++ + K+ H HR+ S DSH K+ Q + R+ + S+
Sbjct: 328 QENHYTDRDYRKERDSHRHREASHR---------DSHWKRHEQEDKPRARDQRE---RSD 375
Query: 837 RSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKT 896
R +K+ K +K S++ + ER++ + +++R SEK ++S++K + K +
Sbjct: 376 RVWKREKDREKYSQR----------EQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRK 425
Query: 897 GKDSGN 902
+ N
Sbjct: 426 ERYENN 431
Score = 39.3 bits (90), Expect = 0.017
Identities = 49/247 (19%), Positives = 107/247 (43%), Gaps = 27/247 (10%)
Query: 701 AEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLES 760
+E+ +RE K++A K + E + L + A E D+++++++++ KE + L
Sbjct: 42 SESLQREAAKKQAMKQTKLE--IQKALAEDATVYEYDSIYDEMQKK--KEENNPKLLLGK 97
Query: 761 ERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDD---DDSHSKKK 817
+RK ++H L + K ++ + KK R+R + D + ++ KK
Sbjct: 98 DRK---PKYIHNLLKAVEIR--KKEQEKRMEKKIQREREMEKGEFDDKEAFVTSAYKKKL 152
Query: 818 RQRSESRSASEHSSSAESERSYKKSKK----HKKKSKKRRHKSDSPE-------SDAERE 866
++R+E + +++ E+ K K ++ + + + P+ S + E
Sbjct: 153 QERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFREARSGIKEE 212
Query: 867 KDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDS-GNWDTSGS---ELSEGELEKRRRTL 922
K + + S K+R Q K + D+ ++D S E+ E + RR +
Sbjct: 213 KSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETRVNCRREKV 272
Query: 923 LEQLDDD 929
+E ++D
Sbjct: 273 IETPEND 279
Score = 37.4 bits (85), Expect = 0.065
Identities = 65/339 (19%), Positives = 126/339 (37%), Gaps = 44/339 (12%)
Query: 608 ELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVNT 667
+L+P + F N T++ K K I+ L + V E ++
Sbjct: 18 QLHPVLQKPSVFGNDSDDDDETSVSESLQREAAKKQAMKQTKLEIQKALAEDATVYEYDS 77
Query: 668 TFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKE------- 720
+++ L ++LL+ E R++E+EK +K++R+
Sbjct: 78 IYDEMQKKKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEF 137
Query: 721 --------SAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHV 772
SA+K L++ A E+ +R A D+T + + ++ ++
Sbjct: 138 DDKEAFVTSAYKKKLQERAEE-------EEREKRAAALEACLDVTKQKDLSGFYRHLLNQ 190
Query: 773 LEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSS 832
E + K S + + K +SR S+ + +++ ++ E +
Sbjct: 191 AVGE-----EEVPKCSFREARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPD 245
Query: 833 AESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRES-EKDRTRQRSESKHKS 891
A+S+ K S E + R ++EK E+ E D RS++ +S
Sbjct: 246 ADSDFDAKSSA--------------DDEIEETRVNCRREKVIETPENDFKHHRSQNHSRS 291
Query: 892 PKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDDQ 930
P ++ G + + T GS S G EKR ++ DQ
Sbjct: 292 PSEERGHSTRH-HTKGSRTSRGH-EKREDQHQQKQSRDQ 328
Score = 36.2 bits (82), Expect = 0.15
Identities = 41/197 (20%), Positives = 75/197 (38%), Gaps = 28/197 (14%)
Query: 706 REREKEEARKMKRKESAFKSMLKQAAPPIE-----LDAVW--EDIRERFVKEPAFEDITL 758
+ER+ R+ ++S +K ++ P D VW E RE++ +
Sbjct: 339 KERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDREKYSQR-------- 390
Query: 759 ESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKR 818
E ER R D + + K+ K+K+ H K + R ++ D ++
Sbjct: 391 EQERDRQQND-------QNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVG 443
Query: 819 QRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEK 878
+S R+ SS S K K ++R +K + D ER ++K S
Sbjct: 444 VQSSERNQDRKESSPNSR------AKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLG 497
Query: 879 DRTRQRSESKHKSPKKK 895
+ R E + K +++
Sbjct: 498 AKHRLTEEGQEKGKEQE 514
Score = 33.9 bits (76), Expect = 0.72
Identities = 38/159 (23%), Positives = 56/159 (35%), Gaps = 20/159 (12%)
Query: 789 KKSKKHHRKRSRSRSGSDSDDDDSHSKK--------KRQRSESRSASEHSSSAESERSYK 840
K + H + S G+DSDDDD S K+Q + + AE Y+
Sbjct: 15 KTQQLHPVLQKPSVFGNDSDDDDETSVSESLQREAAKKQAMKQTKLEIQKALAEDATVYE 74
Query: 841 KSKKHKKKSKKRRHKSDSPESDAER------------EKDKKEKDRESEKDRTRQRSESK 888
+ + KK+ + +R E KKE+++ EK R+R K
Sbjct: 75 YDSIYDEMQKKKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEK 134
Query: 889 HKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLD 927
+ K+ S E E EKR L LD
Sbjct: 135 GEFDDKEAFVTSAYKKKLQERAEEEEREKRAAALEACLD 173
Score = 31.6 bits (70), Expect = 3.6
Identities = 33/193 (17%), Positives = 75/193 (38%), Gaps = 6/193 (3%)
Query: 699 EKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITL 758
++ E ++ R +++ + R K K + E D D K E
Sbjct: 357 KRHEQEDKPRARDQRERSDRVWKREKDREKYSQREQERDRQQNDQNRPSEKGEKEEKSKA 416
Query: 759 ESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDD---DDSHSK 815
+ E ++ K+ E+ ++ + ++ +S + ++ R S S + D D S
Sbjct: 417 KEEHMKVRKERY---ENNDKYRDREKREVGVQSSERNQDRKESSPNSRAKDKFLDQERSN 473
Query: 816 KKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRE 875
K R ++ + ++ S K + ++ +K + + PE+ ++ K E+
Sbjct: 474 KMRNMAKDKERNQEKPSNSESSLGAKHRLTEEGQEKGKEQERPPEAVSKFAKRNNEETVM 533
Query: 876 SEKDRTRQRSESK 888
S +DR R ++
Sbjct: 534 SARDRYLARQMAR 546
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 65.9 bits (159), Expect = 2e-10
Identities = 53/203 (26%), Positives = 91/203 (44%), Gaps = 42/203 (20%)
Query: 740 WEDIRERFVKEPA-------FEDITLESERKRIFKDFMHVLE--HECQHHHSKNKKHSKK 790
WE+++E+ K+ FE+ E+ +K + K +L + KK KK
Sbjct: 31 WEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKK 90
Query: 791 SKKHHRKRSRSR----SGSDSDDDDSHSKKKRQRSESRS-ASEHSSSAESERSYKKSKKH 845
S ++ S S S SDS+D+D K+R++ ++RS S SS +E+E K S K
Sbjct: 91 SGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKK 150
Query: 846 KKKSK---------------KRRHKSDSPESD-------------AEREKDKKEKDRESE 877
KKKSK ++ + D P S A+++K +E+++ +E
Sbjct: 151 KKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATE 210
Query: 878 KDRTRQRSESKHKSPKKKTGKDS 900
K + +++ + K KKK S
Sbjct: 211 KTKKKKKHKKHSKKKKKKAASSS 233
Score = 64.3 bits (155), Expect = 5e-10
Identities = 55/171 (32%), Positives = 81/171 (47%), Gaps = 17/171 (9%)
Query: 751 PAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDD 810
P +E++ + E+K+ K + E E N+ K+ +KH R + SGS+S
Sbjct: 29 PTWEEVKEQLEKKK--KGSKALAEFE----EKMNENWKKELEKH---REKLLSGSESSSK 79
Query: 811 DSHSKKKRQR------SESRSASE-HSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDA 863
KKK ++ S S S+S+ SSS++SE KK K +KK K R HKS S S +
Sbjct: 80 KRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKS-SESSMS 138
Query: 864 EREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGE 914
E E D K+ ++ +K + E K KK S + S LSE E
Sbjct: 139 ETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESE 189
Score = 39.3 bits (90), Expect = 0.017
Identities = 36/163 (22%), Positives = 68/163 (41%), Gaps = 3/163 (1%)
Query: 700 KAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLE 759
++ +++R+R+K+E +K R S+ S ++ + + + +R K+ + E
Sbjct: 75 ESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSE 134
Query: 760 SERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKR-SRSRSGSDSDDDDSHSKKKR 818
S D L+ + + K+ K RK S + S +S ++
Sbjct: 135 SSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEV 194
Query: 819 QRSESRSASEHSSSAESERSYKKSKKH--KKKSKKRRHKSDSP 859
+ + +S+ E + E + KK KKH KKK K DSP
Sbjct: 195 RAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASSSPDSP 237
Score = 35.8 bits (81), Expect = 0.19
Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 13/110 (11%)
Query: 822 ESRSASEHSSSAESERSYKKSKKHKKKSKKRRHK--SDSPESDAEREKDKKEKDR----- 874
E + S A +E K ++ KK+ +K R K S S S +R++ KKEK +
Sbjct: 36 EQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYS 95
Query: 875 ---ESEKDRTRQRSESK---HKSPKKKTGKDSGNWDTSGSELSEGELEKR 918
S D + S+S+ K K++ K + + +S S +SE E + +
Sbjct: 96 SSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSK 145
Score = 33.1 bits (74), Expect = 1.2
Identities = 41/201 (20%), Positives = 85/201 (42%), Gaps = 20/201 (9%)
Query: 399 PRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKK 458
P + + + EKK+ K E EEK K KE ++ ++ L E + + KK
Sbjct: 29 PTWEEVKEQLEKKK--KGSKALAEFEEKMNENWK-KELEKHREKLLSGSESSSKKRQRKK 85
Query: 459 AEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVT 518
E+ ++ S D D ++K+Q K+ +K+ + K+ +M+
Sbjct: 86 KEKKKSGRYSSSSSSSSDSSSSSSDS----EDEDKKQGKRRKKKKNRSHKSSESSMSETE 141
Query: 519 YSTTWSEAQQYLMDNPTFAEDE-----ELQNMDKEDALICFE--------EHIRALEKEE 565
+ S ++ + T E + + + M ED + E E +RA +K+
Sbjct: 142 SDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKS 201
Query: 566 EEEKQKSLLRERRRQRKNRES 586
EE++K+ + +++++ + S
Sbjct: 202 SEEREKATEKTKKKKKHKKHS 222
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 65.9 bits (159), Expect = 2e-10
Identities = 53/203 (26%), Positives = 91/203 (44%), Gaps = 42/203 (20%)
Query: 740 WEDIRERFVKEPA-------FEDITLESERKRIFKDFMHVLE--HECQHHHSKNKKHSKK 790
WE+++E+ K+ FE+ E+ +K + K +L + KK KK
Sbjct: 41 WEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKK 100
Query: 791 SKKHHRKRSRSR----SGSDSDDDDSHSKKKRQRSESRS-ASEHSSSAESERSYKKSKKH 845
S ++ S S S SDS+D+D K+R++ ++RS S SS +E+E K S K
Sbjct: 101 SGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKK 160
Query: 846 KKKSK---------------KRRHKSDSPESD-------------AEREKDKKEKDRESE 877
KKKSK ++ + D P S A+++K +E+++ +E
Sbjct: 161 KKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATE 220
Query: 878 KDRTRQRSESKHKSPKKKTGKDS 900
K + +++ + K KKK S
Sbjct: 221 KTKKKKKHKKHSKKKKKKAASSS 243
Score = 64.3 bits (155), Expect = 5e-10
Identities = 55/171 (32%), Positives = 81/171 (47%), Gaps = 17/171 (9%)
Query: 751 PAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDD 810
P +E++ + E+K+ K + E E N+ K+ +KH R + SGS+S
Sbjct: 39 PTWEEVKEQLEKKK--KGSKALAEFE----EKMNENWKKELEKH---REKLLSGSESSSK 89
Query: 811 DSHSKKKRQR------SESRSASE-HSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDA 863
KKK ++ S S S+S+ SSS++SE KK K +KK K R HKS S S +
Sbjct: 90 KRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKS-SESSMS 148
Query: 864 EREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGE 914
E E D K+ ++ +K + E K KK S + S LSE E
Sbjct: 149 ETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESE 199
Score = 39.3 bits (90), Expect = 0.017
Identities = 36/163 (22%), Positives = 68/163 (41%), Gaps = 3/163 (1%)
Query: 700 KAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLE 759
++ +++R+R+K+E +K R S+ S ++ + + + +R K+ + E
Sbjct: 85 ESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSE 144
Query: 760 SERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKR-SRSRSGSDSDDDDSHSKKKR 818
S D L+ + + K+ K RK S + S +S ++
Sbjct: 145 SSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEV 204
Query: 819 QRSESRSASEHSSSAESERSYKKSKKH--KKKSKKRRHKSDSP 859
+ + +S+ E + E + KK KKH KKK K DSP
Sbjct: 205 RAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASSSPDSP 247
Score = 35.8 bits (81), Expect = 0.19
Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 13/110 (11%)
Query: 822 ESRSASEHSSSAESERSYKKSKKHKKKSKKRRHK--SDSPESDAEREKDKKEKDR----- 874
E + S A +E K ++ KK+ +K R K S S S +R++ KKEK +
Sbjct: 46 EQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYS 105
Query: 875 ---ESEKDRTRQRSESK---HKSPKKKTGKDSGNWDTSGSELSEGELEKR 918
S D + S+S+ K K++ K + + +S S +SE E + +
Sbjct: 106 SSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSK 155
Score = 33.1 bits (74), Expect = 1.2
Identities = 41/201 (20%), Positives = 85/201 (42%), Gaps = 20/201 (9%)
Query: 399 PRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKK 458
P + + + EKK+ K E EEK K KE ++ ++ L E + + KK
Sbjct: 39 PTWEEVKEQLEKKK--KGSKALAEFEEKMNENWK-KELEKHREKLLSGSESSSKKRQRKK 95
Query: 459 AEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVT 518
E+ ++ S D D ++K+Q K+ +K+ + K+ +M+
Sbjct: 96 KEKKKSGRYSSSSSSSSDSSSSSSDS----EDEDKKQGKRRKKKKNRSHKSSESSMSETE 151
Query: 519 YSTTWSEAQQYLMDNPTFAEDE-----ELQNMDKEDALICFE--------EHIRALEKEE 565
+ S ++ + T E + + + M ED + E E +RA +K+
Sbjct: 152 SDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKS 211
Query: 566 EEEKQKSLLRERRRQRKNRES 586
EE++K+ + +++++ + S
Sbjct: 212 SEEREKATEKTKKKKKHKKHS 232
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 65.1 bits (157), Expect = 3e-10
Identities = 58/255 (22%), Positives = 108/255 (42%), Gaps = 25/255 (9%)
Query: 665 VNTTFEDFVAIISSTK-------RSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMK 717
++T E F ++ T+ + ++ ++ + S + A RERER++E R+ K
Sbjct: 12 MDTITESFSQLLLQTRPVSWRLAMRSQIEDRDVLILRGSRVAPAIIRERERQRERERQRK 71
Query: 718 RKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHEC 777
R + + E D E R+R K + +RKR + E E
Sbjct: 72 RAKERHR----------EKDREIEKDRDRQRKRDRERQRWRDRDRKRE-RWGDRDRETET 120
Query: 778 QHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESER 837
+ + ++ +K +K R+R R R D + ++K R R +E E ER
Sbjct: 121 ERQEERERQRDRKREKD-RERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERER 179
Query: 838 SYKKSKKHKKKSKKRRHKSDSP---ESDAEREKDK---KEKDRESEKDRTRQRSESKHKS 891
++ + + +++R K D + EREKD+ +E R+ +K+R R+R K +
Sbjct: 180 QKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRD 239
Query: 892 PKKKTGKDSGNWDTS 906
+K G W+ +
Sbjct: 240 RQKAIDCVPGRWEVT 254
Score = 45.4 bits (106), Expect = 2e-04
Identities = 37/175 (21%), Positives = 73/175 (41%), Gaps = 19/175 (10%)
Query: 756 ITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSK 815
I E ER+R E E Q +K ++H +K ++ + R R R
Sbjct: 56 IIRERERQR---------ERERQRKRAK-ERHREKDREIEKDRDRQRKRDRERQRWRDRD 105
Query: 816 KKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRH-------KSDSPESDAEREKD 868
+KR+R R + E + K+ K + ++R+ + E D +RE++
Sbjct: 106 RKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRERE 165
Query: 869 --KKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRT 921
+ E+ R+ E++R +QR + + +++ K+ D + E + + R T
Sbjct: 166 MGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERET 220
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 65.1 bits (157), Expect = 3e-10
Identities = 43/120 (35%), Positives = 57/120 (47%), Gaps = 3/120 (2%)
Query: 786 KHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKH 845
K K+ KK H+ S S S S D S S+ S+S SA+E S ++ K S+KH
Sbjct: 182 KVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKH 241
Query: 846 KKKSKKRR--HKSDSPESDAER-EKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGN 902
KK+ KKR+ KS S ES+AE E + R E + KSP K K+ N
Sbjct: 242 KKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKN 301
Score = 64.3 bits (155), Expect = 5e-10
Identities = 54/218 (24%), Positives = 104/218 (47%), Gaps = 20/218 (9%)
Query: 695 NSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFE 754
N + ++A+++ R + KE++ K K ++S ++ E+++E KE +
Sbjct: 450 NKVKKRAKSKSRSKSKEKS-KSKERDSKHNRNEEKRMRSRSKGRDHENVKE---KEKQSD 505
Query: 755 DITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHS 814
+ ER R K+ LE + H HSK +K R +SRSR + S++
Sbjct: 506 SKGKDQERSRS-KEKSKQLESKSNEHD-----HSKSKEKDRRAQSRSRECDITKGKHSYN 559
Query: 815 KKKRQRSESRSASEHSSSAESERSYKKSK---KHKKKSKKRRHKSDSPE----SDAEREK 867
+ R+RS SR S S +R +SK +++++ +RR +S S E R K
Sbjct: 560 SRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSK 619
Query: 868 DKKEK---DRESEKDRTRQRSESKHKSPKKKTGKDSGN 902
D++ + R SE++ ++ R++ K+++ + K+ N
Sbjct: 620 DRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKEN 657
Score = 63.5 bits (153), Expect = 9e-10
Identities = 48/178 (26%), Positives = 83/178 (46%), Gaps = 10/178 (5%)
Query: 745 ERFVKEPAFE-DITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRS 803
ER++K E + E++R + + +H K +K K H+ S+ R
Sbjct: 378 ERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERD 437
Query: 804 -GSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESD 862
+S+ DD + K ++R++S+S S S E +S ++ KH + +KR +S S D
Sbjct: 438 IRRNSEKDDKYKNKVKKRAKSKS---RSKSKEKSKSKERDSKHNRNEEKRM-RSRSKGRD 493
Query: 863 AEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRR 920
E K+K+++ KD+ R RS+ K K + K S D S S+ + + R R
Sbjct: 494 HENVKEKEKQSDSKGKDQERSRSKEKSKQLESK----SNEHDHSKSKEKDRRAQSRSR 547
Score = 60.8 bits (146), Expect = 6e-09
Identities = 45/209 (21%), Positives = 95/209 (45%), Gaps = 17/209 (8%)
Query: 699 EKAEARE-REREKEEARKMKRKESAFKSMLKQAAPPIELDAVWED----IRERFVKEPAF 753
+K+E E +E ++ R +RK + +++ + E + +D +ER ++ +
Sbjct: 384 DKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSE 443
Query: 754 EDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSH 813
+D +++ K+ K E ++ KH++ +K R RS+ R + + +
Sbjct: 444 KDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQ 503
Query: 814 SKKK---RQRSESRSASEHSSSAESERSYKKSKKHKKKSKKR---------RHKSDSPES 861
S K ++RS S+ S+ S +E + KSK+ ++++ R +H +S
Sbjct: 504 SDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTR 563
Query: 862 DAEREKDKKEKDRESEKDRTRQRSESKHK 890
+ R +D+ + R DR R RS+ H+
Sbjct: 564 ERSRSRDRSRRVRSRTHDRDRSRSKEYHR 592
Score = 58.2 bits (139), Expect = 4e-08
Identities = 53/244 (21%), Positives = 104/244 (42%), Gaps = 30/244 (12%)
Query: 681 RSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFK-SMLKQAAPPIELDAV 739
RS D N+K K + +ER R KE++++++ K + S K+ + +
Sbjct: 488 RSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSR 547
Query: 740 WEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRS 799
DI + + ++ T E R R + H+ S++K++ + ++ +R+R
Sbjct: 548 ECDITKG---KHSYNSRTRERSRSRDRSRRVRSRTHD--RDRSRSKEYHRYREQEYRRRG 602
Query: 800 RSRS-----------------------GSDSDDDDSHSKKKRQRSESRSASEHSSSAESE 836
RSRS S+ ++ S +K K + ES+S+ +S +
Sbjct: 603 RSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEK 662
Query: 837 RSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKT 896
R Y KS+ H + R K+D +S + K + +D E + + + + K +S +K
Sbjct: 663 RMYSKSRDHNSSNNSREKKADRDQSPFSKIK-QSSQDNELKSSMLKNKEDEKIRSSVEKE 721
Query: 897 GKDS 900
+ S
Sbjct: 722 NQKS 725
Score = 55.5 bits (132), Expect = 2e-07
Identities = 124/614 (20%), Positives = 239/614 (38%), Gaps = 78/614 (12%)
Query: 307 ISTEEQAQLTSTPAIQDQSVEVSSNTGEETSKQETVADFTPKKEEEESQPAKKTYTWNTK 366
+ EE+ + S+ + S + S++ ++S + ++ EE+S+ KK + N++
Sbjct: 183 VKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSE---SATEEKSKKRKKKHRKNSR 239
Query: 367 EEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQT-EKEE 425
+ K+ K +K S + E + R + + E + + EKE
Sbjct: 240 KHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKER 299
Query: 426 KEEARSKYKEAKE------SFQRFL-----ENHEKMTSTTRYK-----KAEQMFGEMEV- 468
K R + +E S+QR L K RY+ ++ F E
Sbjct: 300 KNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETP 359
Query: 469 --WNAISER-DRLEIYEDVLFFLS-KKEKEQAKQLRKRNWEALKNILDNMANVTYSTTW- 523
W +R R+ + + K E + K+ ++ + + + NV+ S
Sbjct: 360 PHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRK 419
Query: 524 SEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKN 583
+E ++ + D+ + +++ +++ ++D + RA K + K+KS +ER + N
Sbjct: 420 NEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERD-SKHN 478
Query: 584 RESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKA 643
R +E ++ S S + + + + ++ G+ + K + K+
Sbjct: 479 R----------NEEKRMRSRSKGRD-HENVKEKEKQSDSKGKDQERSRSKEKSKQLESKS 527
Query: 644 RYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEA 703
HD K + KD+ + RS D K ++NS
Sbjct: 528 NEHDHSKSKE---KDR-----------------RAQSRSRECDITKGKHSYNS-----RT 562
Query: 704 REREREKEEARKMK-RKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESER 762
RER R ++ +R+++ R +S K+ E + R R + + +R
Sbjct: 563 RERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRG-RSRSRERRTPPGRSRSKDR 621
Query: 763 KRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKR---SRSRSGSDSDDDDSHS---KK 816
+R +D E E +K+K +++SK HRK S R S S D +S + +K
Sbjct: 622 RRRRRD-SRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREK 680
Query: 817 KRQRSESRSASEHSSSAESERSY-----KKSKKHKKKSKKRRHKSDSPESDAEREKDKKE 871
K R +S + SS ++E K+ +K + +K KS E+D EK+KK
Sbjct: 681 KADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKK- 739
Query: 872 KDRESEKDRTRQRS 885
D ES +S
Sbjct: 740 FDHESSPGTDEDKS 753
Score = 49.7 bits (117), Expect = 1e-05
Identities = 44/203 (21%), Positives = 92/203 (45%), Gaps = 27/203 (13%)
Query: 699 EKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEP--AFEDI 756
++ + +R R R +K +S + + P+ ++ER + + E
Sbjct: 364 QEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVR-------VKERKITDHRNVSESP 416
Query: 757 TLESERKRIFKDFM-HVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSK 815
++E+++ KD + E + + + K+ K+ K KK + +SRS+S
Sbjct: 417 NRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKS------------ 464
Query: 816 KKRQRSESRSA-SEHSSSAESE-RSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKD 873
+++S+S+ S+H+ + E RS K + H+ +K + +SDS D ER + K++
Sbjct: 465 --KEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEK-QSDSKGKDQERSRSKEKSK 521
Query: 874 RESEKDRTRQRSESKHKSPKKKT 896
+ K S+SK K + ++
Sbjct: 522 QLESKSNEHDHSKSKEKDRRAQS 544
Score = 48.9 bits (115), Expect = 2e-05
Identities = 32/143 (22%), Positives = 65/143 (45%), Gaps = 7/143 (4%)
Query: 784 NKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAES---ERSYK 840
+K + K++ R R + +D + R+ + + +H S+++ R+ +
Sbjct: 384 DKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSE 443
Query: 841 KSKKHKKKSKKR-RHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKD 899
K K+K K KKR + KS S + + K++ K +E+ R R RS+ + K+ K
Sbjct: 444 KDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQ 503
Query: 900 SGNWDTSGSELSEGELEKRRRTL 922
S D+ G + +++ + L
Sbjct: 504 S---DSKGKDQERSRSKEKSKQL 523
Score = 47.0 bits (110), Expect = 8e-05
Identities = 55/230 (23%), Positives = 99/230 (43%), Gaps = 20/230 (8%)
Query: 704 REREREKE------EARKMKRKESAFKS--MLKQAAPPIELDAVWEDIRERFVKE---PA 752
RERERE+E + +R+ +S +K P R+RF + P
Sbjct: 302 RERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPH 361
Query: 753 FEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDS 812
+ ++R R+ + + + + K + S K RK + R+ S+S + +
Sbjct: 362 WRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKE-RKITDHRNVSESPNRKN 420
Query: 813 HSKKKRQRSESRSASEH-SSSAESERSYKKSKKHKKKSKKR---RHKSDSPESDAEREKD 868
+KK + +S S ++E + YK K + KSK R + KS S E D++ ++
Sbjct: 421 EKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRN 480
Query: 869 KKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKR 918
++++ R K R + + K K K GKD + S S+ +LE +
Sbjct: 481 EEKRMRSRSKGRDHENVKEKEKQSDSK-GKDQ---ERSRSKEKSKQLESK 526
Score = 40.4 bits (93), Expect = 0.008
Identities = 31/154 (20%), Positives = 63/154 (40%), Gaps = 12/154 (7%)
Query: 755 DITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHS 814
D + +S+ D E + + K++K+S+K KK +KR +S+ + S+ + +
Sbjct: 205 DSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENL 264
Query: 815 KKKRQRS----ESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAE------ 864
+ + Q + E E+ K+ K + ++R + + P S
Sbjct: 265 EAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRL 324
Query: 865 --REKDKKEKDRESEKDRTRQRSESKHKSPKKKT 896
+K K R + RT RS S+ + + +T
Sbjct: 325 LVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSET 358
Score = 37.7 bits (86), Expect = 0.050
Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 38/121 (31%)
Query: 790 KSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKS 849
K KK +KR +S S S S DS S S+S+S+S+ S S + + + K K
Sbjct: 182 KVKKEEKKRHKSSSSSSSSSSDSDSS-----SDSQSSSDSSDS-------ESATEEKSKK 229
Query: 850 KKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSE 909
+K++H+ +S K KKEK K+K K S + ++
Sbjct: 230 RKKKHRKNS-------RKHKKEKK-------------------KRKKSKKSASSESEAEN 263
Query: 910 L 910
L
Sbjct: 264 L 264
Score = 35.0 bits (79), Expect = 0.32
Identities = 21/80 (26%), Positives = 32/80 (40%), Gaps = 13/80 (16%)
Query: 834 ESERSYKKSKKHKKKSKKRRHKSDSPES-------------DAEREKDKKEKDRESEKDR 880
+S+ ++ K+HK S SDS S A EK KK K + + R
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSR 239
Query: 881 TRQRSESKHKSPKKKTGKDS 900
++ + K K KK +S
Sbjct: 240 KHKKEKKKRKKSKKSASSES 259
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 65.1 bits (157), Expect = 3e-10
Identities = 50/162 (30%), Positives = 74/162 (45%), Gaps = 8/162 (4%)
Query: 760 SERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQ 819
SE K ++ F+ V + H SK K+ K +K ++ S RS S H +KR
Sbjct: 1784 SEEKDDYEIFVKVKD---THEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRT 1840
Query: 820 RSESRS-ASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEK 878
SESRS A + SS ++S RS +S+ +S++RR S S R KEK + S K
Sbjct: 1841 -SESRSRARKRSSKSKSHRSQTRSRS---RSRRRRRSSRSRSKSRGRRSVSKEKRKRSPK 1896
Query: 879 DRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRR 920
R++ R + +S + K + S S RRR
Sbjct: 1897 HRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRR 1938
Score = 56.6 bits (135), Expect = 1e-07
Identities = 69/260 (26%), Positives = 103/260 (39%), Gaps = 39/260 (15%)
Query: 653 KDILKDKGFVVEVNTTFE-DFVAII--SSTKRSTTLDAGNIKLAFNSLLEKAEARERERE 709
K+ L D GF + E D V + +R T+L AG LL R+R
Sbjct: 1713 KETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAG----IEGPLLASDVGRDRSAA 1768
Query: 710 KEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFE--------DITLESE 761
M + S S K E+ +D E+ K + D +L S
Sbjct: 1769 SPVVSSMPERASESSSEEKD---DYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSR 1825
Query: 762 RKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRS 821
KR K H S+ +K S KSK H R ++RSRS S+++R+ S
Sbjct: 1826 SKRS-KSSEHKSRKRTSESRSRARKRSSKSKSH-RSQTRSRS---------RSRRRRRSS 1874
Query: 822 ESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRT 881
SRS S S E+ K+S KH+ KS++R+ K S +D ++ R + RT
Sbjct: 1875 RSRSKSRGRRSVSKEKR-KRSPKHRSKSRERKRKRSS-------SRDNRKTVR--ARSRT 1924
Query: 882 RQRSESKHKSPKKKTGKDSG 901
R H +++ + G
Sbjct: 1925 PSRRSRSHTPSRRRRSRSVG 1944
Score = 53.1 bits (126), Expect = 1e-06
Identities = 30/132 (22%), Positives = 55/132 (41%), Gaps = 2/132 (1%)
Query: 790 KSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKS 849
K K H K ++++ + + R RS+ +SEH S + S +S+ K+ S
Sbjct: 1795 KVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSES--RSRARKRSS 1852
Query: 850 KKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSE 909
K + H+S + R + + + R + R E + +SPK ++ S S
Sbjct: 1853 KSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSR 1912
Query: 910 LSEGELEKRRRT 921
+ + R RT
Sbjct: 1913 DNRKTVRARSRT 1924
Score = 49.3 bits (116), Expect = 2e-05
Identities = 53/234 (22%), Positives = 95/234 (40%), Gaps = 14/234 (5%)
Query: 677 SSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIEL 736
S +KRS + + + K S ++ AR+R + + R R S + + + +
Sbjct: 1824 SRSKRSKSSEHKSRKRTSES---RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKS 1880
Query: 737 DAVWEDIRERFVKEPAFEDITLESERKRIF-KDFMHVLEHECQHHHSKNKKHSKKSKKHH 795
+E+ + P + E +RKR +D + + +++ H+ ++
Sbjct: 1881 RGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRS 1940
Query: 796 RKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHS--SSAESERSYKKSKKHKKKSKKRR 853
R R RS S S S + +R R+ SR + S S S RS S++ + S++RR
Sbjct: 1941 RSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRR 2000
Query: 854 HKSD--------SPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKD 899
+S SP + + S R R RS + +SPK+ T D
Sbjct: 2001 SRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLD 2054
Score = 38.9 bits (89), Expect = 0.022
Identities = 83/405 (20%), Positives = 148/405 (36%), Gaps = 58/405 (14%)
Query: 203 LITKSNLHAMIKAEESSKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAA 262
LI K H + A +S E P T+ T + T A A ++
Sbjct: 1540 LIAKEMEHNTVCAAGTSPVGEIGEEKILPTSETKQRTVLDTYPGVSEADAGETLSSTGPF 1599
Query: 263 AAAAANANASTSASNTVSGTVPVVPEPEVTSIVATVVDNENTVTISTE----EQAQLTST 318
A S T + T+ +V + +V + T D E+ + IST +A +
Sbjct: 1600 ALEPDATGTSKGIEFTTASTLSLVNKYDV-DLSLTTQDTEHDMVISTSPSGGSEADIEGP 1658
Query: 319 PAIQDQSVEVSSNTG-----------EETSKQETVADFTPKK----EEEESQPAKKTYTW 363
+D +++ SN + S Q A +PK+ E+E P K+T
Sbjct: 1659 LPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLAALLSPKESSGGEKEVPPPPKETLPD 1718
Query: 364 NTKEEAKQAFKEL-LKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTE 422
+ + E L +P + +++ I P LA + ++ + V +
Sbjct: 1719 SGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGP---LLASDVGRDRSAASPVVSSM 1775
Query: 423 KEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYE 482
E E+ S+ K+ E F + + HEK K GE E S R R
Sbjct: 1776 PERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDK-----GEKEKKRDSSLRSR----- 1825
Query: 483 DVLFFLSKKEKEQAKQLRKRNWE----ALKNILDNMANVTYSTTWSEAQQYLMDNPTFAE 538
SK+ K + RKR E A K + ++ + + + S +++ + + ++
Sbjct: 1826 ------SKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSK 1879
Query: 539 DEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKN 583
+++ KE K + K +S RER+R+R +
Sbjct: 1880 SRGRRSVSKE--------------KRKRSPKHRSKSRERKRKRSS 1910
Score = 38.9 bits (89), Expect = 0.022
Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 6/119 (5%)
Query: 812 SHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSK--KRRHKSDSPESDAEREKDK 869
S ++ S S ++ + + +++KSKK+K + K K + + S S ++R K
Sbjct: 1773 SSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSS 1832
Query: 870 KEKDRE---SEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQ 925
+ K R+ + R R+RS SK KS + +T S + S S + RR E+
Sbjct: 1833 EHKSRKRTSESRSRARKRS-SKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEK 1890
Score = 35.4 bits (80), Expect = 0.25
Identities = 31/88 (35%), Positives = 41/88 (46%), Gaps = 22/88 (25%)
Query: 817 KRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRES 876
K +SR S + + E KKSKKHKK HK+ +K KK+K++E
Sbjct: 84 KEGSRKSRCVSVQTDPTD-EIPTKKSKKHKK------HKN---------KKKKKKKEKEK 127
Query: 877 EKDRTRQRSESKHKSPKKKTGKDSGNWD 904
+ R + SESK KS D GN D
Sbjct: 128 KYKRQPEESESKTKS------HDDGNID 149
Score = 32.0 bits (71), Expect = 2.7
Identities = 36/148 (24%), Positives = 59/148 (39%), Gaps = 14/148 (9%)
Query: 223 ECTTTSTAPVPTTEIPTTM----STMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNT 278
E +T+ P TT + MAA E++A V ++A ++ +S
Sbjct: 1324 EVSTSLLVPAVTTPVLAESILEPPAMAAPESSAMAVLESSAVTVLESSTVTVLESSTVTV 1383
Query: 279 VSGTVPVVPEPE-------VTSIVATVVDNENTVTISTEEQAQLTSTPAIQDQSVEVSSN 331
+ +V VPEP VT V V E +V + + L + + + SV V +
Sbjct: 1384 LEPSVVTVPEPPVVAEPDYVTIPVPVVSALEPSVPVLEPAVSVLQPSMIVSEPSVSVQES 1443
Query: 332 TGEETSKQETVADFT---PKKEEEESQP 356
T + TV++ T P + ES P
Sbjct: 1444 TVTVSEPAVTVSEQTQVIPTEVAIESTP 1471
Score = 31.6 bits (70), Expect = 3.6
Identities = 38/182 (20%), Positives = 71/182 (39%), Gaps = 14/182 (7%)
Query: 183 AKPKELEDLEGYQNT----IVAGSLITKSNLHAMIKAEESSKQEECTTTSTAPVPTTEIP 238
++P LE L+ T +V+ S+I++ + ++ E S + + + APVPTT +
Sbjct: 197 SEPHILETLKPATKTAELSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTL- 255
Query: 239 TTMSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNTVSGTVPVVPEPEVTSIVATV 298
+ ++E + + + + + S V V V EP T +V++
Sbjct: 256 ----VLKSSEPVVTMSVEYQMKSVLKSVESTSPEPSKIMLVEPPVAKVLEPSETLVVSSE 311
Query: 299 VDNENTVTISTEEQAQLTSTPAIQ-----DQSVEVSSNTGEETSKQETVADFTPKKEEEE 353
E ST + AI+ +Q V+V S + + + PK E
Sbjct: 312 TPTEVYPEPSTSTTMDFPESSAIEALRLPEQPVDVPSEIADSSMTRPQELPELPKTTALE 371
Query: 354 SQ 355
Q
Sbjct: 372 LQ 373
Score = 31.6 bits (70), Expect = 3.6
Identities = 28/131 (21%), Positives = 55/131 (41%), Gaps = 11/131 (8%)
Query: 219 SKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNT 278
++Q T +T P TE+P++ S + ++ V + + +A + +++ S
Sbjct: 1184 TEQSALTAENTWP---TEVPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVL 1240
Query: 279 VSGTVPVVPEP--------EVTSIVATVVDNENTVTISTEEQAQLTSTPAIQDQSVEVSS 330
VS VPEP +T + + VV E+ V ++ TPA+ + ++S
Sbjct: 1241 VSEAAVTVPEPPPEPESSITLTPVESAVVAEEHEVVPERPVTCMVSETPAMSAEPTVLAS 1300
Query: 331 NTGEETSKQET 341
+ ET
Sbjct: 1301 EPPVMSETAET 1311
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 65.1 bits (157), Expect = 3e-10
Identities = 50/162 (30%), Positives = 74/162 (45%), Gaps = 8/162 (4%)
Query: 760 SERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQ 819
SE K ++ F+ V + H SK K+ K +K ++ S RS S H +KR
Sbjct: 1784 SEEKDDYEIFVKVKD---THEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRT 1840
Query: 820 RSESRS-ASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEK 878
SESRS A + SS ++S RS +S+ +S++RR S S R KEK + S K
Sbjct: 1841 -SESRSRARKRSSKSKSHRSQTRSRS---RSRRRRRSSRSRSKSRGRRSVSKEKRKRSPK 1896
Query: 879 DRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRR 920
R++ R + +S + K + S S RRR
Sbjct: 1897 HRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRR 1938
Score = 56.6 bits (135), Expect = 1e-07
Identities = 69/260 (26%), Positives = 103/260 (39%), Gaps = 39/260 (15%)
Query: 653 KDILKDKGFVVEVNTTFE-DFVAII--SSTKRSTTLDAGNIKLAFNSLLEKAEARERERE 709
K+ L D GF + E D V + +R T+L AG LL R+R
Sbjct: 1713 KETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAG----IEGPLLASDVGRDRSAA 1768
Query: 710 KEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFE--------DITLESE 761
M + S S K E+ +D E+ K + D +L S
Sbjct: 1769 SPVVSSMPERASESSSEEKD---DYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSR 1825
Query: 762 RKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRS 821
KR K H S+ +K S KSK H R ++RSRS S+++R+ S
Sbjct: 1826 SKRS-KSSEHKSRKRTSESRSRARKRSSKSKSH-RSQTRSRS---------RSRRRRRSS 1874
Query: 822 ESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRT 881
SRS S S E+ K+S KH+ KS++R+ K S +D ++ R + RT
Sbjct: 1875 RSRSKSRGRRSVSKEKR-KRSPKHRSKSRERKRKRSS-------SRDNRKTVR--ARSRT 1924
Query: 882 RQRSESKHKSPKKKTGKDSG 901
R H +++ + G
Sbjct: 1925 PSRRSRSHTPSRRRRSRSVG 1944
Score = 53.1 bits (126), Expect = 1e-06
Identities = 30/132 (22%), Positives = 55/132 (41%), Gaps = 2/132 (1%)
Query: 790 KSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKS 849
K K H K ++++ + + R RS+ +SEH S + S +S+ K+ S
Sbjct: 1795 KVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSES--RSRARKRSS 1852
Query: 850 KKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSE 909
K + H+S + R + + + R + R E + +SPK ++ S S
Sbjct: 1853 KSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSR 1912
Query: 910 LSEGELEKRRRT 921
+ + R RT
Sbjct: 1913 DNRKTVRARSRT 1924
Score = 49.3 bits (116), Expect = 2e-05
Identities = 53/234 (22%), Positives = 95/234 (40%), Gaps = 14/234 (5%)
Query: 677 SSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIEL 736
S +KRS + + + K S ++ AR+R + + R R S + + + +
Sbjct: 1824 SRSKRSKSSEHKSRKRTSES---RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKS 1880
Query: 737 DAVWEDIRERFVKEPAFEDITLESERKRIF-KDFMHVLEHECQHHHSKNKKHSKKSKKHH 795
+E+ + P + E +RKR +D + + +++ H+ ++
Sbjct: 1881 RGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRS 1940
Query: 796 RKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHS--SSAESERSYKKSKKHKKKSKKRR 853
R R RS S S S + +R R+ SR + S S S RS S++ + S++RR
Sbjct: 1941 RSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRR 2000
Query: 854 HKSD--------SPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKD 899
+S SP + + S R R RS + +SPK+ T D
Sbjct: 2001 SRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLD 2054
Score = 38.9 bits (89), Expect = 0.022
Identities = 83/405 (20%), Positives = 148/405 (36%), Gaps = 58/405 (14%)
Query: 203 LITKSNLHAMIKAEESSKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAA 262
LI K H + A +S E P T+ T + T A A ++
Sbjct: 1540 LIAKEMEHNTVCAAGTSPVGEIGEEKILPTSETKQRTVLDTYPGVSEADAGETLSSTGPF 1599
Query: 263 AAAAANANASTSASNTVSGTVPVVPEPEVTSIVATVVDNENTVTISTE----EQAQLTST 318
A S T + T+ +V + +V + T D E+ + IST +A +
Sbjct: 1600 ALEPDATGTSKGIEFTTASTLSLVNKYDV-DLSLTTQDTEHDMVISTSPSGGSEADIEGP 1658
Query: 319 PAIQDQSVEVSSNTG-----------EETSKQETVADFTPKK----EEEESQPAKKTYTW 363
+D +++ SN + S Q A +PK+ E+E P K+T
Sbjct: 1659 LPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLAALLSPKESSGGEKEVPPPPKETLPD 1718
Query: 364 NTKEEAKQAFKEL-LKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTE 422
+ + E L +P + +++ I P LA + ++ + V +
Sbjct: 1719 SGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGP---LLASDVGRDRSAASPVVSSM 1775
Query: 423 KEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYE 482
E E+ S+ K+ E F + + HEK K GE E S R R
Sbjct: 1776 PERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDK-----GEKEKKRDSSLRSR----- 1825
Query: 483 DVLFFLSKKEKEQAKQLRKRNWE----ALKNILDNMANVTYSTTWSEAQQYLMDNPTFAE 538
SK+ K + RKR E A K + ++ + + + S +++ + + ++
Sbjct: 1826 ------SKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSK 1879
Query: 539 DEELQNMDKEDALICFEEHIRALEKEEEEEKQKSLLRERRRQRKN 583
+++ KE K + K +S RER+R+R +
Sbjct: 1880 SRGRRSVSKE--------------KRKRSPKHRSKSRERKRKRSS 1910
Score = 38.9 bits (89), Expect = 0.022
Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 6/119 (5%)
Query: 812 SHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSK--KRRHKSDSPESDAEREKDK 869
S ++ S S ++ + + +++KSKK+K + K K + + S S ++R K
Sbjct: 1773 SSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSS 1832
Query: 870 KEKDRE---SEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQ 925
+ K R+ + R R+RS SK KS + +T S + S S + RR E+
Sbjct: 1833 EHKSRKRTSESRSRARKRS-SKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEK 1890
Score = 35.4 bits (80), Expect = 0.25
Identities = 31/88 (35%), Positives = 41/88 (46%), Gaps = 22/88 (25%)
Query: 817 KRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRES 876
K +SR S + + E KKSKKHKK HK+ +K KK+K++E
Sbjct: 84 KEGSRKSRCVSVQTDPTD-EIPTKKSKKHKK------HKN---------KKKKKKKEKEK 127
Query: 877 EKDRTRQRSESKHKSPKKKTGKDSGNWD 904
+ R + SESK KS D GN D
Sbjct: 128 KYKRQPEESESKTKS------HDDGNID 149
Score = 32.0 bits (71), Expect = 2.7
Identities = 36/148 (24%), Positives = 59/148 (39%), Gaps = 14/148 (9%)
Query: 223 ECTTTSTAPVPTTEIPTTM----STMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNT 278
E +T+ P TT + MAA E++A V ++A ++ +S
Sbjct: 1324 EVSTSLLVPAVTTPVLAESILEPPAMAAPESSAMAVLESSAVTVLESSTVTVLESSTVTV 1383
Query: 279 VSGTVPVVPEPE-------VTSIVATVVDNENTVTISTEEQAQLTSTPAIQDQSVEVSSN 331
+ +V VPEP VT V V E +V + + L + + + SV V +
Sbjct: 1384 LEPSVVTVPEPPVVAEPDYVTIPVPVVSALEPSVPVLEPAVSVLQPSMIVSEPSVSVQES 1443
Query: 332 TGEETSKQETVADFT---PKKEEEESQP 356
T + TV++ T P + ES P
Sbjct: 1444 TVTVSEPAVTVSEQTQVIPTEVAIESTP 1471
Score = 31.6 bits (70), Expect = 3.6
Identities = 38/182 (20%), Positives = 71/182 (39%), Gaps = 14/182 (7%)
Query: 183 AKPKELEDLEGYQNT----IVAGSLITKSNLHAMIKAEESSKQEECTTTSTAPVPTTEIP 238
++P LE L+ T +V+ S+I++ + ++ E S + + + APVPTT +
Sbjct: 197 SEPHILETLKPATKTAELSVVSTSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTL- 255
Query: 239 TTMSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNTVSGTVPVVPEPEVTSIVATV 298
+ ++E + + + + + S V V V EP T +V++
Sbjct: 256 ----VLKSSEPVVTMSVEYQMKSVLKSVESTSPEPSKIMLVEPPVAKVLEPSETLVVSSE 311
Query: 299 VDNENTVTISTEEQAQLTSTPAIQ-----DQSVEVSSNTGEETSKQETVADFTPKKEEEE 353
E ST + AI+ +Q V+V S + + + PK E
Sbjct: 312 TPTEVYPEPSTSTTMDFPESSAIEALRLPEQPVDVPSEIADSSMTRPQELPELPKTTALE 371
Query: 354 SQ 355
Q
Sbjct: 372 LQ 373
Score = 31.6 bits (70), Expect = 3.6
Identities = 28/131 (21%), Positives = 55/131 (41%), Gaps = 11/131 (8%)
Query: 219 SKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANASTSASNT 278
++Q T +T P TE+P++ S + ++ V + + +A + +++ S
Sbjct: 1184 TEQSALTAENTWP---TEVPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVL 1240
Query: 279 VSGTVPVVPEP--------EVTSIVATVVDNENTVTISTEEQAQLTSTPAIQDQSVEVSS 330
VS VPEP +T + + VV E+ V ++ TPA+ + ++S
Sbjct: 1241 VSEAAVTVPEPPPEPESSITLTPVESAVVAEEHEVVPERPVTCMVSETPAMSAEPTVLAS 1300
Query: 331 NTGEETSKQET 341
+ ET
Sbjct: 1301 EPPVMSETAET 1311
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 64.7 bits (156), Expect = 4e-10
Identities = 47/167 (28%), Positives = 79/167 (47%), Gaps = 23/167 (13%)
Query: 778 QHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESER 837
+ S++K+ S+ + +RSRSR S + + R+RS SRS S S+
Sbjct: 50 ERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGN 109
Query: 838 SYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKD--------------RTRQ 883
KSKK + +S+ + K+D ES E++KDK +K+ E EKD + ++
Sbjct: 110 ---KSKKTENRSRSKE-KTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKE 165
Query: 884 RSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDDQ 930
R E + +KK ++ G E+ +G ++ LE DDD+
Sbjct: 166 RVEKWREEQRKKAMENIGELKKEIEEMKQG-----KKWSLEDDDDDE 207
Score = 59.7 bits (143), Expect = 1e-08
Identities = 38/143 (26%), Positives = 66/143 (46%), Gaps = 3/143 (2%)
Query: 790 KSKKHHRKRSRSRSGSDS-DDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKH-KK 847
+ +H+RKRS SR S S S S K+ +R + R + ERS + K+ +
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62
Query: 848 KSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSG 907
+ +KR +S S E D RE+ ++ + R+ + R+R R S K + N S
Sbjct: 63 RDRKRLRRSRSRERDRSRER-RRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSK 121
Query: 908 SELSEGELEKRRRTLLEQLDDDQ 930
+ GE K ++ + +D++
Sbjct: 122 EKTDGGESSKEKKKDKDDKEDEK 144
Score = 57.8 bits (138), Expect = 5e-08
Identities = 36/143 (25%), Positives = 67/143 (46%), Gaps = 8/143 (5%)
Query: 783 KNKKHSKKSKKHHRKRSRSRSGSDSDD-----DDSHSKKK---RQRSESRSASEHSSSAE 834
+++ + K+S R SRSRS S SD DD S+ + R+R SRS + S +
Sbjct: 4 ESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSR 63
Query: 835 SERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKK 894
+ ++S+ ++ + R +S S + R + + + R S +++E++ +S +K
Sbjct: 64 DRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEK 123
Query: 895 KTGKDSGNWDTSGSELSEGELEK 917
G +S + E E EK
Sbjct: 124 TDGGESSKEKKKDKDDKEDEKEK 146
Score = 57.4 bits (137), Expect = 6e-08
Identities = 41/149 (27%), Positives = 70/149 (46%), Gaps = 11/149 (7%)
Query: 789 KKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERS--YKKSKKHK 846
K+SK+ +RSRSR + K+R RS R S S E +RS ++S+
Sbjct: 30 KRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRD 89
Query: 847 KKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKK-----KTGKDSG 901
++ + R + S + K KK ++R K++T SK K K + KD+G
Sbjct: 90 RRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAG 149
Query: 902 NWDTSGSELSEGELEKRRRTLLEQLDDDQ 930
N+D + E E ++R+ +E+ ++Q
Sbjct: 150 NFDQNKLE----EEMRKRKERVEKWREEQ 174
Score = 50.4 bits (119), Expect = 7e-06
Identities = 38/169 (22%), Positives = 73/169 (43%), Gaps = 8/169 (4%)
Query: 761 ERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQR 820
+RKR+ + + + S+++ + + +RSRS S + SKK R
Sbjct: 64 DRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNK------SKKTENR 117
Query: 821 SESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDR 880
S S+ ++ S++ ++ K K+ +K+ + E + + K++ EK RE ++ +
Sbjct: 118 SRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKK 177
Query: 881 TRQR-SESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLL-EQLD 927
+ E K + + K GK D E E EK + E+LD
Sbjct: 178 AMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELD 226
Score = 37.7 bits (86), Expect = 0.050
Identities = 39/199 (19%), Positives = 76/199 (38%), Gaps = 24/199 (12%)
Query: 680 KRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAV 739
+RS + D + L ++ +RER+R +E R R +S
Sbjct: 50 ERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSR------------- 96
Query: 740 WEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRS 799
R R + + + + ++E + K E SK KK K K+ ++
Sbjct: 97 ---SRGRRSRSSSPGNKSKKTENRSRSK------EKTDGGESSKEKKKDKDDKED--EKE 145
Query: 800 RSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSP 859
+ D + + +K+++R E + + E+ KK + K+ KK + D
Sbjct: 146 KDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDD 205
Query: 860 ESDAEREKDKKEKDRESEK 878
+ D E +K+ + E E+
Sbjct: 206 DEDDPAEAEKEGNEMEGEE 224
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 64.3 bits (155), Expect = 5e-10
Identities = 60/282 (21%), Positives = 115/282 (40%), Gaps = 21/282 (7%)
Query: 650 KIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEARERERE 709
K+++ + +++ + +T E F A K+ + L + + ++
Sbjct: 160 KLVEQLKEERELLRSTTSTIESFAA---QEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQ 216
Query: 710 KEEARKMKRKESAFKSML-KQAAPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKD 768
K+K K L K+ P + + ++ +ER +E E E ERKR ++
Sbjct: 217 HMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREE 276
Query: 769 FMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASE 828
E E + + ++ +S+ H R+ R S S D ++R+RS SR
Sbjct: 277 E----EREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRR 332
Query: 829 HSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDA-EREKDKKEKDRESEKDRTRQRSES 887
S SER ++ + +++SK R KS S + +RE+D+K K++E
Sbjct: 333 SRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKE------------ 380
Query: 888 KHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDD 929
K S KK+ SG+ + + + E + + +D
Sbjct: 381 KRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSED 422
Score = 64.3 bits (155), Expect = 5e-10
Identities = 61/228 (26%), Positives = 89/228 (39%), Gaps = 25/228 (10%)
Query: 690 IKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVK 749
IK L EK R E +++E K +++E E + E RE +
Sbjct: 223 IKATVEELKEKLRKRTEEPDRDERLKKEKQERE------------EREKEREREREERER 270
Query: 750 EPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDD 809
+ E+ E ER R ++ +H + + +S+ H R RSR R S S D
Sbjct: 271 KRRREEEEREKERARD-RERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRD 329
Query: 810 DDSHSKKKRQRSESRSASEHSSSAESERSYK----KSKKHKKKSKKRRHKSDSPESDAER 865
++R RS RS +H S + R K KS KH+ KS+ R S E +
Sbjct: 330 ------RRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRG 383
Query: 866 EKDKKE--KDRESEKDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELS 911
DKK K EK +ESK K + S + + G S
Sbjct: 384 SDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSEGDTQS 431
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.122 0.337
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,818,427
Number of Sequences: 37866
Number of extensions: 1882477
Number of successful extensions: 43104
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 786
Number of HSP's successfully gapped in prelim test: 1100
Number of HSP's that attempted gapping in prelim test: 16835
Number of HSP's gapped (non-prelim): 15015
length of query: 930
length of database: 18,247,518
effective HSP length: 112
effective length of query: 818
effective length of database: 14,006,526
effective search space: 11457338268
effective search space used: 11457338268
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.