Guide to the Human Genome
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Search of human proteins with 151301137

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|151301137 AT-hook transcription factor [Homo sapiens]
         (1439 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|151301137 AT-hook transcription factor [Homo sapiens]             2935   0.0  
gi|163965366 nascent polypeptide-associated complex alpha subuni...    77   1e-13
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    69   2e-11
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    65   5e-10
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    64   1e-09
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  62   5e-09
gi|209862789 microtubule associated monoxygenase, calponin and L...    59   3e-08
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    58   8e-08
gi|55741677 SET domain containing 1A [Homo sapiens]                    57   1e-07
gi|55750053 atrophin-1 [Homo sapiens]                                  57   1e-07
gi|55750041 atrophin-1 [Homo sapiens]                                  57   1e-07
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]         57   1e-07
gi|150170670 piccolo isoform 2 [Homo sapiens]                          57   2e-07
gi|150378539 piccolo isoform 1 [Homo sapiens]                          57   2e-07
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         56   3e-07
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]                  55   4e-07
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        55   4e-07
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         55   6e-07
gi|188536004 zinc finger protein 469 [Homo sapiens]                    54   1e-06
gi|11386183 WAS protein family, member 2 [Homo sapiens]                53   2e-06
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ...    53   2e-06
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ...    53   2e-06
gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ...    53   2e-06
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ...    53   2e-06
gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ...    53   2e-06
gi|91754185 hypothetical protein LOC254268 [Homo sapiens]              53   2e-06
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    52   3e-06
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              50   2e-05
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          50   2e-05
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          50   2e-05

>gi|151301137 AT-hook transcription factor [Homo sapiens]
          Length = 1439

 Score = 2935 bits (7609), Expect = 0.0
 Identities = 1439/1439 (100%), Positives = 1439/1439 (100%)

Query: 1    MASSETEIRWAEPGLGKGPQRRRWAWAEDKRDVDRSSSQSWEEERLFPNATSPELLEDFR 60
            MASSETEIRWAEPGLGKGPQRRRWAWAEDKRDVDRSSSQSWEEERLFPNATSPELLEDFR
Sbjct: 1    MASSETEIRWAEPGLGKGPQRRRWAWAEDKRDVDRSSSQSWEEERLFPNATSPELLEDFR 60

Query: 61   LAQQHLPPLEWDPHPQPDGHQDSESGETSGEEAEAEDVDSPASSHEPLAWLPQQGRQLDM 120
            LAQQHLPPLEWDPHPQPDGHQDSESGETSGEEAEAEDVDSPASSHEPLAWLPQQGRQLDM
Sbjct: 61   LAQQHLPPLEWDPHPQPDGHQDSESGETSGEEAEAEDVDSPASSHEPLAWLPQQGRQLDM 120

Query: 121  TEEEPDGTLGSLEVEEAGESSSRLGYEAGLSLEGHGNTSPMALGHGQARGWVASGEQASG 180
            TEEEPDGTLGSLEVEEAGESSSRLGYEAGLSLEGHGNTSPMALGHGQARGWVASGEQASG
Sbjct: 121  TEEEPDGTLGSLEVEEAGESSSRLGYEAGLSLEGHGNTSPMALGHGQARGWVASGEQASG 180

Query: 181  DKLSEHSEVNPSVELSPARSWSSGTVSLDHPSDSLDSTWEGETDGPQPTALAETLPEGPS 240
            DKLSEHSEVNPSVELSPARSWSSGTVSLDHPSDSLDSTWEGETDGPQPTALAETLPEGPS
Sbjct: 181  DKLSEHSEVNPSVELSPARSWSSGTVSLDHPSDSLDSTWEGETDGPQPTALAETLPEGPS 240

Query: 241  HHLLSPDGRTGGSVARATPMEFQDSSAPPAQSPQHATDRWRRETTRFFCPQPKEHIWKQT 300
            HHLLSPDGRTGGSVARATPMEFQDSSAPPAQSPQHATDRWRRETTRFFCPQPKEHIWKQT
Sbjct: 241  HHLLSPDGRTGGSVARATPMEFQDSSAPPAQSPQHATDRWRRETTRFFCPQPKEHIWKQT 300

Query: 301  KTSPKPLPSRFIGSISPLNPQPRPTRQGRPLPRQGATLAGRSSSNAPKYGRGQLNYPLPD 360
            KTSPKPLPSRFIGSISPLNPQPRPTRQGRPLPRQGATLAGRSSSNAPKYGRGQLNYPLPD
Sbjct: 301  KTSPKPLPSRFIGSISPLNPQPRPTRQGRPLPRQGATLAGRSSSNAPKYGRGQLNYPLPD 360

Query: 361  FSKVGPRVRFPKDESYRPPKSRSHNRKPQAPARPLIFKSPAEIVQEVLLSSGEAALAKDT 420
            FSKVGPRVRFPKDESYRPPKSRSHNRKPQAPARPLIFKSPAEIVQEVLLSSGEAALAKDT
Sbjct: 361  FSKVGPRVRFPKDESYRPPKSRSHNRKPQAPARPLIFKSPAEIVQEVLLSSGEAALAKDT 420

Query: 421  PPAHPITRVPQEFQTPEQATELVHQLQEDYHRLLTKYAEAENTIDQLRLGAKVNLFSDPP 480
            PPAHPITRVPQEFQTPEQATELVHQLQEDYHRLLTKYAEAENTIDQLRLGAKVNLFSDPP
Sbjct: 421  PPAHPITRVPQEFQTPEQATELVHQLQEDYHRLLTKYAEAENTIDQLRLGAKVNLFSDPP 480

Query: 481  QPNHSIHTGMVPQGTKVLSFTIPQPRSAEWWPGPAEDPQASAASGWPSARGDLSPSSLTS 540
            QPNHSIHTGMVPQGTKVLSFTIPQPRSAEWWPGPAEDPQASAASGWPSARGDLSPSSLTS
Sbjct: 481  QPNHSIHTGMVPQGTKVLSFTIPQPRSAEWWPGPAEDPQASAASGWPSARGDLSPSSLTS 540

Query: 541  MPTLGWLPENRDISEDQSSAEQTQALASQASQFLAKVESFERLIQAGRLMPQDQVKGFQR 600
            MPTLGWLPENRDISEDQSSAEQTQALASQASQFLAKVESFERLIQAGRLMPQDQVKGFQR
Sbjct: 541  MPTLGWLPENRDISEDQSSAEQTQALASQASQFLAKVESFERLIQAGRLMPQDQVKGFQR 600

Query: 601  LKAAHAALEEEYLKACREQHPAQPLAGSKGTPGRFDPRRELEAEIYRLGSCLEELKEHID 660
            LKAAHAALEEEYLKACREQHPAQPLAGSKGTPGRFDPRRELEAEIYRLGSCLEELKEHID
Sbjct: 601  LKAAHAALEEEYLKACREQHPAQPLAGSKGTPGRFDPRRELEAEIYRLGSCLEELKEHID 660

Query: 661  QTQQEPEPPGSDSALDSTPALPCLHQPTHLPAPSGQAPMPAIKTSCPEPATTTAAASTGP 720
            QTQQEPEPPGSDSALDSTPALPCLHQPTHLPAPSGQAPMPAIKTSCPEPATTTAAASTGP
Sbjct: 661  QTQQEPEPPGSDSALDSTPALPCLHQPTHLPAPSGQAPMPAIKTSCPEPATTTAAASTGP 720

Query: 721  CPLHVNVEVSSGNSEVEDRPQDPLARLRHKELQMEQVYHGLMERYLSVKSLPEAMRMEEE 780
            CPLHVNVEVSSGNSEVEDRPQDPLARLRHKELQMEQVYHGLMERYLSVKSLPEAMRMEEE
Sbjct: 721  CPLHVNVEVSSGNSEVEDRPQDPLARLRHKELQMEQVYHGLMERYLSVKSLPEAMRMEEE 780

Query: 781  EEGEEEEEEEGGGDSLEVDGVAATPGKAEATRVLPRQCPVQAEKSHGAPLEEATEKMVSM 840
            EEGEEEEEEEGGGDSLEVDGVAATPGKAEATRVLPRQCPVQAEKSHGAPLEEATEKMVSM
Sbjct: 781  EEGEEEEEEEGGGDSLEVDGVAATPGKAEATRVLPRQCPVQAEKSHGAPLEEATEKMVSM 840

Query: 841  KPPGFQASLARDGHMSGLGKAEAAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLP 900
            KPPGFQASLARDGHMSGLGKAEAAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLP
Sbjct: 841  KPPGFQASLARDGHMSGLGKAEAAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLP 900

Query: 901  QKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAA 960
            QKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAA
Sbjct: 901  QKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAA 960

Query: 961  SVPRDGASYPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMA 1020
            SVPRDGASYPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMA
Sbjct: 961  SVPRDGASYPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMA 1020

Query: 1021 VPGSEFEGHKRISEQPLPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAICEL 1080
            VPGSEFEGHKRISEQPLPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAICEL
Sbjct: 1021 VPGSEFEGHKRISEQPLPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAICEL 1080

Query: 1081 QEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLP 1140
            QEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLP
Sbjct: 1081 QEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLP 1140

Query: 1141 GEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDG 1200
            GEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDG
Sbjct: 1141 GEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDG 1200

Query: 1201 KRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDP 1260
            KRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDP
Sbjct: 1201 KRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDP 1260

Query: 1261 LGPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPR 1320
            LGPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPR
Sbjct: 1261 LGPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPR 1320

Query: 1321 PPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPPP 1380
            PPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPPP
Sbjct: 1321 PPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPPP 1380

Query: 1381 ARRHRHSIQLDLGDLEELNKALSRAVQAAESVRSTTRQMRSSLSADLRQAHSLRGSCLF 1439
            ARRHRHSIQLDLGDLEELNKALSRAVQAAESVRSTTRQMRSSLSADLRQAHSLRGSCLF
Sbjct: 1381 ARRHRHSIQLDLGDLEELNKALSRAVQAAESVRSTTRQMRSSLSADLRQAHSLRGSCLF 1439


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 145/621 (23%), Positives = 210/621 (33%), Gaps = 90/621 (14%)

Query: 797  EVDGVAATPGKAEATRVLPRQCPVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMS 856
            +VDG++ T   A      P++CP +   +      + T   ++  P     S++      
Sbjct: 750  KVDGISHTSALAPVASS-PKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRP 808

Query: 857  GLGKAEAAPPGP-GVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRG--GGPHLE 913
               K  A P  P G    P     A+    +  S +GS  S      P      G P   
Sbjct: 809  PTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPS 868

Query: 914  ETWMASP--------ETDS-GFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPR 964
                 SP        ET +   V     +  P T  P+   +   T+ +  +  A   P+
Sbjct: 869  AVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPK 928

Query: 965  DGASYPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGS 1024
               + P  +G+  P  AT PS            P+ P  + AP            A P S
Sbjct: 929  GIPASPSPKGAPTPPAATPPSPK--------GGPATPSPKWAPT--------PPAATPPS 972

Query: 1025 EFEGHKRISEQPLPNKTISPPPAP-------APAAAPLPCGPTETIPSFLLTRAGRDQAI 1077
               G    S +  P    + PP+P       +P  AP P  P  T PS            
Sbjct: 973  PKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTP--PAVTPPS------------ 1018

Query: 1078 CELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTE 1137
                 + S            P   +P  P  +       +G P    AT  S  G  +T 
Sbjct: 1019 ----PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATP 1074

Query: 1138 RLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAA 1197
             L G P       PP  +   ++  P+    +  ++    P   L +   K    +P A 
Sbjct: 1075 SLKGAPT-PPAATPPSPKGGPATPSPKGA-PMPPAATPPSPKGGLATPPHKGAPTTPAAT 1132

Query: 1198 RDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPK---AVPKGNGTVSCPHCRPIRTQDAGG 1254
                +G G A  P +    G  T       SPK   A P   G  + P   P      GG
Sbjct: 1133 PPSPKG-GLATPPPK----GAPTTPAATPPSPKGGLATPPPKGAPTTPAATP--PSPKGG 1185

Query: 1255 AVTGDPLGPP--PADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQR- 1311
              T  P G P  PA T   P  G     P+    G+ T+ A    + +   +TPSPK   
Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGGLATPSPK----GAPTTPAATPPSPKGGLATPSPKGAP 1241

Query: 1312 --------SKQAGSSPRPPPGLWYLATAPPAPAPPAF-AYISSVPIMPYPPAAVYYAPA- 1361
                    S + G +  PP G    A  PPA  PP+    +++ P    P  AV   P+ 
Sbjct: 1242 TTPAATPPSPKGGPATPPPKG----APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP 1297

Query: 1362 --GPTSAQP-AAKWPPTASPP 1379
              GP ++ P  A  PP A+PP
Sbjct: 1298 KGGPATSPPKGAPTPPAATPP 1318



 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 145/581 (24%), Positives = 205/581 (35%), Gaps = 93/581 (16%)

Query: 842  PPGFQASLARDG--HMSGLGKAEAAPPGPGVPPHPPGTKSAASHQSSMTSLE------GS 893
            PPG +     DG  H S L    ++P     P    G  + AS + ++T L       G 
Sbjct: 745  PPGTKKV---DGISHTSALAPVASSPKE--CPTEDSGASATASSKGTLTYLADSPSPLGV 799

Query: 894  GISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSPLTQT--PEHRLSHISTA 951
             +S +  + P  +G          A P+T    +G+ +S VSP+  +  PE+ LS   + 
Sbjct: 800  SVSPQTKRPPTKKGS---------AGPDTP---IGNLSSPVSPVEASFLPENSLSFQGSK 847

Query: 952  GTLAQPFAASVPRD-GASYPKARGSLIPRRATEP--STPRSQAQRY---LSSPSGPLRQR 1005
             + A   + + P   GA  P A   L P+  T P   TP             P+ P  ++
Sbjct: 848  DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907

Query: 1006 APNFSLE-------RTLAAEMAVPGSEFEGHKRISEQPLPNKTISPPPAPAPAAAPLPCG 1058
            AP  S+        R   A   +P S             P      P  P+P  AP P  
Sbjct: 908  APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP-- 965

Query: 1059 PTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRG 1118
            P  T PS     A             +    +   +   P +G+PT PA     P   +G
Sbjct: 966  PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP-KGAPTPPAVT---PPSPKG 1021

Query: 1119 RPADSPATWGSHYGSKSTERLPGEPRGEEQI--VPPGRQRARSSSVPREVLRLSLSSESE 1176
             PA +P   G+     +T   P  P+G      +P G     ++++P      S      
Sbjct: 1022 SPAATPFPKGASTPPAAT---PPSPKGSPAATPLPKGAPTTPAATLP------SPKGGPA 1072

Query: 1177 LPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPK---AVP 1233
             PSL         T  SP+            G P   + +G          SPK   A P
Sbjct: 1073 TPSLKGAPTPPAATPPSPK------------GGPATPSPKGAPMPPAATPPSPKGGLATP 1120

Query: 1234 KGNGTVSCPHCRPIRTQDAGGAVTGDPLGPP--PADTLQCPLCGQVGSPPEADGPGSATS 1291
               G  + P   P      GG  T  P G P  PA T   P  G    PP+    G+ T+
Sbjct: 1121 PHKGAPTTPAATP--PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK----GAPTT 1174

Query: 1292 GAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAFAYISSVPI--- 1348
             A    + +   +TPSPK       ++P  P G   LAT  P  AP   A     P    
Sbjct: 1175 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKG--GLATPSPKGAPTTPAATPPSPKGGL 1232

Query: 1349 -------MPYPPAAVYYAP-AGPTSAQPAAKWPPTASPPPA 1381
                    P  PAA   +P  GP +  P     P A+ PP+
Sbjct: 1233 ATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPS 1273



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 135/627 (21%), Positives = 210/627 (33%), Gaps = 91/627 (14%)

Query: 800  GVAATPGKAEATRVLPRQCPVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLG 859
            G  ATP    A    P   P   +     P  +      +  PP  +  LA   H     
Sbjct: 1230 GGLATPSPKGAPTT-PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPN 1288

Query: 860  KAEAAPPGPG-----VPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEE 914
             A   PP P       PP    T  AA+  S   S  G+   +  P  P      P    
Sbjct: 1289 PAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS-PGTPPPKGAPTPPAVTPPSPKGTP 1347

Query: 915  TWMASPETDSGFVGSETSRVSPL--TQTPEHRLSHISTA-------------GTLAQPF- 958
            T  A+  +  G   + +S+  P     TP H+     T              G    P  
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV 1407

Query: 959  ---------AASVPRDGASYPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNF 1009
                     A  V R+GA+ P ++G L P   T  S  ++ A    S+P G      P+ 
Sbjct: 1408 IPLSPKKAPATPVTREGAATP-SKGDLTPPAVTPVSLKKAPAT---SAPKGG--PATPSS 1461

Query: 1010 SLERTLAAEMAVPGSEFEGHKRISEQPLPNKTISPPPAPAPAAAP-----LPCGPTETIP 1064
              + TL A       E    K+++    P K    P  PAP  AP     +P  P E +P
Sbjct: 1462 KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKA---PATPAPMGAPTLPAVIPSSPKE-VP 1517

Query: 1065 SFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRG--RPAD 1122
            +   +R         L  + +   L  +++L  P    P+        P +T     P +
Sbjct: 1518 ATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPS--------PKKTPAIPTPKE 1569

Query: 1123 SPATWGSHYGSKSTERLP----GEPRGEEQIVPPGRQRARSSSVPREVLR---LSLSSES 1175
            +PAT  S   S      P    G P  +E ++PP    A +S  P+E      ++  S  
Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGAPSPKELLIPP----AVTSPSPKEAPTPPAVTPPSPE 1625

Query: 1176 ELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKG 1235
            + P+ P       +   +P + +D          P  VT +   T  +    + K +P  
Sbjct: 1626 KGPATPAPKGTPTSPPVTPSSLKDSPTS------PASVTCKMGATVPQ----ASKGLPAK 1675

Query: 1236 NGTVSCPHCRPIRTQDAGGAVTGDPLGPPP---ADTLQCPLCGQVGSPPEADGPGSATSG 1292
             G  +          ++   +T      P    +     P+C    +   + GP S  + 
Sbjct: 1676 KGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAP 1735

Query: 1293 AEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYP 1352
            A     ++ +S T     + K A  SP+ P         P + A       +   ++P P
Sbjct: 1736 APLLPVQKDSSKT----AKGKDASHSPKGP------LAPPESKASTPLTAAAFEKVLPKP 1785

Query: 1353 PAAVYYAPAGPTSAQPAAKWPPTASPP 1379
             +A   A   P  + P A  P    PP
Sbjct: 1786 ESASVSAAPSPPVSLPLAPSPVPTLPP 1812



 Score = 50.8 bits (120), Expect = 9e-06
 Identities = 163/743 (21%), Positives = 234/743 (31%), Gaps = 86/743 (11%)

Query: 666  PEPPGSDSALDSTPALPCLHQPTHLPAPSGQAPMPAIKTSCPEPATTTAAASTGPC-PLH 724
            P P GS +A       P     T LP+P G    P++K +   PA T  +   GP  P  
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAAT-LPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099

Query: 725  VNVEVSSGNSEVEDRPQDPLARLRHKELQMEQVYHGLMERYLSVKSLPEAMRMEEEEEGE 784
                +    +     P+  LA   HK                   + P A     +    
Sbjct: 1100 KGAPMPP--AATPPSPKGGLATPPHK----------------GAPTTPAATPPSPK---- 1137

Query: 785  EEEEEEGGGDSLEVDGVAATPGKAEATRVLPRQCPVQAEKSHGAPLEEATEKMVSMKPPG 844
                           G+A  P K   T   P   P   +     P  +      +  PP 
Sbjct: 1138 --------------GGLATPPPKGAPTT--PAATPPSPKGGLATPPPKGAPTTPAATPPS 1181

Query: 845  FQASLARDGHMSGLGKAEAAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPL 904
             +  LA            A PP P      P  K A +  ++       G++   P+   
Sbjct: 1182 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK--- 1238

Query: 905  HRGGGPHLEETWMASPETDSGFVGSETSRVSPL--TQTPEHRLSHISTAGTLAQPFAASV 962
               G P    T  A+P +  G   +   + +P     TP      ++T      P  A V
Sbjct: 1239 ---GAP---TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV 1292

Query: 963  ----PRDGASYPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAE 1018
                P+ G +    +G+  P  AT PS   S           P     P+     TL A 
Sbjct: 1293 TPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPA- 1351

Query: 1019 MAVPGSEFEGHKRISEQPLPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAIC 1078
               P S+       S++       +P     PA  P        IPS          A+ 
Sbjct: 1352 -TTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPS--PKGDPTSPAVI 1408

Query: 1079 ELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWG-SHYGSKSTE 1137
             L  + +       +    P +G  T PA     P   +  PA S    G +   SK   
Sbjct: 1409 PLSPKKAPATPVTREGAATPSKGDLTPPAVT---PVSLKKAPATSAPKGGPATPSSKGDP 1465

Query: 1138 RLPG--EPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKS-KTTKDSP 1194
             LP    P  +E   PP  ++  +SS P++    +  +    P+LP     S K    +P
Sbjct: 1466 TLPAVTPPSPKE---PPAPKQVATSSSPKKAP--ATPAPMGAPTLPAVIPSSPKEVPATP 1520

Query: 1195 QAARDGKRGVG---SAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQD 1251
             + RD         S   P  +  +         V SPK  P        P     +   
Sbjct: 1521 SSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEAS 1580

Query: 1252 AGGAVTGDPL-GPPPADTLQCPLCGQVGSPPEADGPGSATSGA-EKATTRRKASSTP-SP 1308
            +  AVT     G P    L  P      SP EA  P + T  + EK         TP SP
Sbjct: 1581 SPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP 1640

Query: 1309 KQRSKQAGSSPRPPPGLWYL--ATAPPA----PAPPAFAYISSVPIMPYPPAA-VYYAPA 1361
                     SP  P  +     AT P A    PA      +  V + P P +  +  AP 
Sbjct: 1641 PVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPT 1700

Query: 1362 --GPTSAQPAAKWPPTASPPPAR 1382
              GP + + +A  PP    P A+
Sbjct: 1701 RKGPQTKKSSATSPPICPDPSAK 1723



 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 124/542 (22%), Positives = 178/542 (32%), Gaps = 79/542 (14%)

Query: 884  QSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSPLTQTPEH 943
            Q+   SLEG+  S    Q  L     P +     A+P+    F  + +S   PL+  PE 
Sbjct: 533  QTVPASLEGAPFSPA--QAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLS--PEA 588

Query: 944  RLSHIST---------AGTLAQPF-----AASVPRDGASYPKARGSLIPRRATEPSTPRS 989
             L+  S          A ++  P      A+ +  D  + P + G L+      P+    
Sbjct: 589  TLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAF 648

Query: 990  QAQRYLSSPSGPLRQRAPNFSLERTLAAEMA------VPGSEFEGHKRISEQPL-PNKTI 1042
              +   + P+G     A   S   T A+          P +       ++  PL P  + 
Sbjct: 649  PLES--ADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASE 706

Query: 1043 SPPPAPAPAAAPLPCGPT-------ETIPSFLLTRAGRDQAICELQ--EEVSRLRLRLED 1093
            + P AP+P     P           +++PS  L  AG      ++      S L      
Sbjct: 707  NCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASS 766

Query: 1094 SLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLPGEPRGEEQIVPPG 1153
                P + S    ASA      T    ADSP+  G    S  T+R P +        P G
Sbjct: 767  PKECPTEDSG---ASATASSKGTLTYLADSPSPLGVSV-SPQTKRPPTKKGSAGPDTPIG 822

Query: 1154 RQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRV 1213
               +  S V             E   LP  S   + +KDSP               P   
Sbjct: 823  NLSSPVSPV-------------EASFLPENSLSFQGSKDSPATTHS----------PTPP 859

Query: 1214 TFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDPLGPPPADTLQCPL 1273
            + +G  T      LSPK V         P    +     G A       P  + T   P 
Sbjct: 860  SPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPK 919

Query: 1274 CGQV-----GSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYL 1328
              +      G P      G+ T  A    + +   +TPSPK       ++P  P G    
Sbjct: 920  KARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPAT 979

Query: 1329 ATAPPAPAPPAFAYIS--------SVPIMPYPPAAVYYAPAGPTSAQP---AAKWPPTAS 1377
             +   AP PPA    S        S    P PPA    +P G  +A P    A  PP A+
Sbjct: 980  PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT 1039

Query: 1378 PP 1379
            PP
Sbjct: 1040 PP 1041



 Score = 35.4 bits (80), Expect = 0.40
 Identities = 80/356 (22%), Positives = 114/356 (32%), Gaps = 53/356 (14%)

Query: 198  ARSWSSGTVSL--DHPSDSLDSTWEGETDGPQPTALAETLPEGPSHHLLSPDGRTGGSVA 255
            A + S GT++   D PS  L  +   +T  P PT      P+ P  +L SP      S  
Sbjct: 779  ATASSKGTLTYLADSPSP-LGVSVSPQTKRP-PTKKGSAGPDTPIGNLSSPVSPVEASFL 836

Query: 256  RATPMEFQDSSAPPAQSPQHATDRWRRETTRFFCPQPKEHIWKQTKTSPKPLPSRFIGSI 315
                + FQ S   PA +                 P P       T ++  PL  +  G  
Sbjct: 837  PENSLSFQGSKDSPATT---------------HSPTPPSPKGAPTPSAVTPLSPK--GVT 879

Query: 316  SPLNPQPRPTRQGRPLPRQG-ATLAGRS------SSNAPKYGRGQLNYPLPDFSKVGPRV 368
             P    P P+    P P++G AT A +       +S++PK  R     P P      P  
Sbjct: 880  LPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARAT---PAPKGIPASPSP 936

Query: 369  R-FPKDESYRPPKSRSHNRKPQ---APARPLIFKSPAEIVQEVLLSSGEAALAKDTPPA- 423
            +  P   +  PP  +     P    AP  P       +         G       TPP+ 
Sbjct: 937  KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSP 996

Query: 424  --HPITRVPQEFQTPEQATELVHQLQEDYHRLLTKYAEAENTIDQLRLGAKVNLFSDPPQ 481
               P T  P+   TP   T                  +          GA     + PP 
Sbjct: 997  KGGPATPSPKGAPTPPAVT--------------PPSPKGSPAATPFPKGASTPPAATPPS 1042

Query: 482  PNHSIHTGMVPQGTKVL-SFTIPQPRSAEWWPGPAEDPQASAASGWPSARGDLSPS 536
            P  S     +P+G     + T+P P+     P     P   AA+      G  +PS
Sbjct: 1043 PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPS 1098



 Score = 34.7 bits (78), Expect = 0.68
 Identities = 108/515 (20%), Positives = 170/515 (33%), Gaps = 106/515 (20%)

Query: 918  ASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAG--TLAQPFAASVPRD----GASYPK 971
            A P T   F  S  S ++PL Q+    +  +   G   L+ P   ++  D    GASYP 
Sbjct: 293  AGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPS 352

Query: 972  ARGSLIP---RRATEPSTPR-------------SQAQRYLSSPSGPLRQRAPNFSLERTL 1015
             R  + P   R    P+T               S       SPSG L   A +FSL  T 
Sbjct: 353  QRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNV-ATSFSLSPTT 411

Query: 1016 AAEMAVPGSEFEGHKRISEQPLPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQ 1075
            +  +    +    +  +++ P+ +   +P     P    +   PT T           + 
Sbjct: 412  SLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCT--IAAAPTTTF----------EV 459

Query: 1076 AICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKS 1135
            A C      S     +E          PT PA+    P   +  P+   AT         
Sbjct: 460  ATCVSPPMSSGPISNIE----------PTSPAALVMAPVAPK-EPSTQVAT--------- 499

Query: 1136 TERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSK------- 1188
            T R+P        + PP        ++P  VL +   ++ +L ++P   E +        
Sbjct: 500  TLRIP--------VSPPLPDPEDLKNLPSSVL-VKFPTQKDLQTVPASLEGAPFSPAQAG 550

Query: 1189 -TTKDSP------QAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSC 1241
             TTK  P      QAA        S      +    + T  +  +  P  + K   +++ 
Sbjct: 551  LTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTS 610

Query: 1242 P-----HCRPIRTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKA 1296
            P         I+T    G    D  GP    +L  P       P E+  P        K 
Sbjct: 611  PLGVNSSASVIKTDSYAGP---DSAGPLLKSSLITPTVAAF--PLESADPAGVAPTTAKG 665

Query: 1297 TTRRKASSTP--------SPKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAFAYISSVPI 1348
            T+    +++P        +PK    + G+    P         P AP+P           
Sbjct: 666  TSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCA------ 719

Query: 1349 MPYPPAAVYYAPAGPTSAQPAAKWPPTASPPPARR 1383
               P A +  AP  P S  P+   PP  +PP  ++
Sbjct: 720  ---PLATLVLAPEIPKSV-PSPSLPPAGTPPGTKK 750



 Score = 32.0 bits (71), Expect = 4.4
 Identities = 30/120 (25%), Positives = 51/120 (42%), Gaps = 14/120 (11%)

Query: 255  ARATPMEFQDSSAPPAQSPQHATDRWRRETTRFFCPQPKEHIWKQTKTSPKPLPSRFIGS 314
            A ATP   +++S+PPA +P          +T    P PKE +     TSP P  +    +
Sbjct: 1570 APATPSS-KEASSPPAVTP----------STYKGAPSPKELLIPPAVTSPSPKEAPTPPA 1618

Query: 315  ISPLNPQ---PRPTRQGRPLPRQGATLAGRSSSNAPKYGRGQLNYPLPDFSKVGPRVRFP 371
            ++P +P+     P  +G P        + + S  +P     ++   +P  SK  P  + P
Sbjct: 1619 VTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP 1678


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 160/653 (24%), Positives = 210/653 (32%), Gaps = 159/653 (24%)

Query: 820  VQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGK----AEAAPPGPGVPPHPP 875
            +QA  S G+P  +AT   ++M P   QASL      +         +A    P  PP   
Sbjct: 412  LQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQT 471

Query: 876  GTKSAASHQSSMTSLEG----SGISERLPQKPLHRGGGPHLE-ETWMASPETDSGFVGSE 930
                A S  SS  ++      S ++   PQ PL     P LE ++ +A P   +      
Sbjct: 472  SLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLT 531

Query: 931  TSRV--------------------------------------SPLTQTPEHRLSHISTAG 952
            T  +                                      SPLT  P    S I+T  
Sbjct: 532  TPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP 591

Query: 953  TLAQPFAASVPRDGASYPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLE 1012
              A P  AS P  G   P     L P     P  P   A   L +P  P    +P  S  
Sbjct: 592  PQAPPALASPPLQGLPSPP----LSPLATPPPQAPPXLALPPLQAPPSP--PASPPLS-- 643

Query: 1013 RTLAAEMAVPGSEFEGHKRISEQPLPNKTISPPPAP------APAAAPLPCGPTETIPSF 1066
                  +A P  +      +     P    SPPP+P      +P A+P P  P+ T PS 
Sbjct: 644  -----PLATPSPQAPNALAVHLLQAP---FSPPPSPPVQAPFSPPASP-PVSPSATPPS- 693

Query: 1067 LLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPAT 1126
                    QA   L                 PLQ  P+ PAS    P+ T    A  P  
Sbjct: 694  --------QAPPSLAAP--------------PLQVPPSPPASPPMSPSATPPPQAPPPLA 731

Query: 1127 WGSHYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEK 1186
                    S    P  P       PP R     ++ P   L++  S  + LP  PL    
Sbjct: 732  APPLQVPPSP---PASPPMSPSATPPPRVPPLLAAPP---LQVPPSPPASLPMSPL---- 781

Query: 1187 SKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQ--YTGHEYHVLSPKAVPKGNGTVSCPHC 1244
                K  PQA          A      +F GQ  ++      +SP A P        P  
Sbjct: 782  ---AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP-------PQA 831

Query: 1245 RPIRTQDAGGAVTGDPLGPPPADTLQCP-------------------LCGQVGSPPEADG 1285
             P+        +   P  PP + TLQ P                          PP +  
Sbjct: 832  PPV----LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 887

Query: 1286 PGSATSGAEKATTRRKASSTPSPKQ---RSKQAGSSPRPPPGLWYLATAPPA----PAPP 1338
            P S  SG + A     A+STP   +      + G++  PPP     A  P A    PAPP
Sbjct: 888  PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPP 947

Query: 1339 -AFAYISSVPIMPYPPA---------AVYYAPAGPTSAQPAAKWPPTASPPPA 1381
             AF      P +P+PPA            Y   GP SA PA   P    P P+
Sbjct: 948  LAFRGAPGAP-LPWPPATGPGSADGLCTIYETEGPESATPA---PGALDPGPS 996



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 137/571 (23%), Positives = 189/571 (33%), Gaps = 77/571 (13%)

Query: 859  GKAEAAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMA 918
            G+ E APP     P P  +   AS  +    L   G+     ++ + RG           
Sbjct: 98   GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL-RISAEETVARGKATE------- 149

Query: 919  SPETDSGFVGSETSRVSPLTQTPEHRLSHIS-TAGT---LAQPFAASVPRDGASYP-KAR 973
            +P+  +   G+      P   TP   ++  S  AGT   L +P  ++ PR     P K+ 
Sbjct: 150  APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV 209

Query: 974  GSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRIS 1033
             S      TEPS     A+R  S+  G  R  + + S   T  +  A  G    G  R  
Sbjct: 210  SSASEHSTTEPS---PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266

Query: 1034 EQP-----------LPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQE 1082
              P            P +   P    APA  PL   P  T PS   T+A   + +     
Sbjct: 267  AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT-PSPSGTKA---RPVPPPDN 322

Query: 1083 EVSRLRLRLEDS--LHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLP 1140
              + L   L  S  L  PL  +P  P++    P   +  P+  PAT  S      T    
Sbjct: 323  AATPLPATLPPSPPLATPLPLAPPSPSA----PPSLQTLPS-PPATPPSQAPPSMTTPPM 377

Query: 1141 GEPRGEEQIVP---PGRQRARSSSVPREVLRLS---------------------LSSESE 1176
              P   + I P   P    + S   P   L LS                     +S    
Sbjct: 378  QAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQT 437

Query: 1177 LPSLPLFSEKSKTTKDSP----QAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAV 1232
              SL   S  + T  DSP      +      + ++  P         T H    LS  A 
Sbjct: 438  QASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLAS 497

Query: 1233 PKGNGTVSCPHCRPIRTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSPPEADGPGSATSG 1292
                  +S     P+ TQ    ++    L  PPA     PL     + P    P   T+ 
Sbjct: 498  HSPQAPLSSLIMPPLETQ---SSLAPPSLQTPPASLTTPPL----ENLPSLAPPPLQTAS 550

Query: 1293 AEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAFAY--ISSVPIMP 1350
            A   T   +    P+P            PPP        PP  APPA A   +  +P  P
Sbjct: 551  APLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPP 610

Query: 1351 YPPAAVYYAPAGPTSAQPAAKWPPT--ASPP 1379
              P A     A P  A P  + PP+  ASPP
Sbjct: 611  LSPLATPPPQAPPXLALPPLQAPPSPPASPP 641



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 128/515 (24%), Positives = 176/515 (34%), Gaps = 111/515 (21%)

Query: 951  AGTLAQPFAASVPRDGASYPKARGSLIPRRATEPSTPR-----------SQAQRYLSSPS 999
            AG  A+  AA  P  G   P+  GS  P     P+  R             A+R      
Sbjct: 10   AGAAARTPAARAP--GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67

Query: 1000 GPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTISPPPAPAPAAAPLPCGP 1059
              + + AP     R+       P S      R    P P K  SP P  +P  A    G 
Sbjct: 68   ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAP-PAKNTSPGPVSSPGRAS---GT 123

Query: 1060 TETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGR 1119
            T   P   L + G              LR+  E+++ +  + +     SA    AR R  
Sbjct: 124  TRPGP---LGQKG--------------LRISAEETVARG-KATEAPKRSALSAGAR-RDT 164

Query: 1120 PADSPATWGSHYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPS 1179
               +P T       +S  R  G   G  +  P  R R      P E  R S+SS SE   
Sbjct: 165  SGPTPGTPSPAMARRS--RAAGTEVGLPRPAPSARPRP-----PTEGPRKSVSSASE--- 214

Query: 1180 LPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSP-KAVPKGNGT 1238
                     TT+ SP A R    G G      R       +     + SP ++ P   GT
Sbjct: 215  -------HSTTEPSPAARRRPSAGGGLQRPASR-----SLSSSATPLSSPARSGPSARGT 262

Query: 1239 VSCPHCRPIRTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATT 1298
               P   P + +  G      P   PP      P  G + S P A               
Sbjct: 263  PRAP-AHPSQPKPKGLQALRPPQVTPPRKDA-APALGPLSSSPLA--------------- 305

Query: 1299 RRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAA--- 1355
                  TPSP      +G+  RP P     AT  PA  PP+    + +P+ P  P+A   
Sbjct: 306  ------TPSP------SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPS 353

Query: 1356 ---VYYAPAGPTS-AQPAAKWPPTASPP-----PARRHRHSI----------QLDLGDLE 1396
               +   PA P S A P+   PP  +PP     P  +  HS+           L L  L+
Sbjct: 354  LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQ 413

Query: 1397 ELNKALSRAVQAAES-VRSTTRQMRSSLSADLRQA 1430
                  S  +QA  S +  + RQ ++SL++  R A
Sbjct: 414  ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPA 448



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 127/521 (24%), Positives = 169/521 (32%), Gaps = 90/521 (17%)

Query: 815  PRQCPVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGKAEAAPPGPGVPPHP 874
            P  CP+QA  S        T   ++  PP    +LA    + GL     +P     P  P
Sbjct: 564  PAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA-SPPLQGLPSPPLSPLATPPPQAP 622

Query: 875  P--GTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMA---SPETDSGFVGS 929
            P        +  S   S   S ++   PQ P       HL +   +   SP   + F   
Sbjct: 623  PXLALPPLQAPPSPPASPPLSPLATPSPQAP--NALAVHLLQAPFSPPPSPPVQAPFSPP 680

Query: 930  ETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATEP----- 984
             +  VSP    P           +LA P     P   AS P +  +  P +A  P     
Sbjct: 681  ASPPVSPSATPPS------QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 734

Query: 985  -STPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTIS 1043
               P S       SPS     R P       L    + P S            LP   ++
Sbjct: 735  LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPAS------------LPMSPLA 782

Query: 1044 PPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQEEVSRLRL---RLEDSLHQP-L 1099
             PP  AP A   P  P + +PS   +  G+          +S L     +    L  P L
Sbjct: 783  KPPPQAPPALATP--PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 840

Query: 1100 QGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERL-PGEPRGEEQIVPPGRQRAR 1158
            Q  P+ PAS    P     R   +P    S  G + T  L PG P       PP R    
Sbjct: 841  QVPPSPPAS----PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP------PPPSR---- 886

Query: 1159 SSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQ 1218
                       S SS    P L   S  + +T +  +    G  G  +A  P        
Sbjct: 887  -----------SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA----- 930

Query: 1219 YTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDP--LGPPPADTLQCPLCGQ 1276
                E     P A  +G          P+  + A GA    P   GP  AD L C +   
Sbjct: 931  ----ELAACHPAAWSRGPAP-------PLAFRGAPGAPLPWPPATGPGSADGL-CTIYET 978

Query: 1277 VG------SPPEAD-GPGSATSGAEKATTRRKASSTPSPKQ 1310
             G      +P   D GP   TSG + A      +S+ SPKQ
Sbjct: 979  EGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 1019


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 119/482 (24%), Positives = 167/482 (34%), Gaps = 95/482 (19%)

Query: 961  SVPRDG---ASYPKARGS---LIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERT 1014
            S PR G    S P A G      P + T P    S  +   ++  GPL Q+    S E T
Sbjct: 73   SAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 132

Query: 1015 LAAEMAVPGSEFE----GHKRISEQPLPNKTISPP--------------PAPAPAAAPLP 1056
            +A   A    +      G +R +  P P  T SP               P PAP+A P P
Sbjct: 133  VARGKATEAPKRSALSAGARRDTSGPTPG-TPSPAMARRSRAAGTEVGLPRPAPSARPRP 191

Query: 1057 CGPTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASA--FDRPA 1114
              PTE          G  +++    E           S  +P   +  RP++     RPA
Sbjct: 192  --PTE----------GPRKSVSSASEH----------STTEPSPAARRRPSAGGGLQRPA 229

Query: 1115 R----TRGRPADSPATWGSHYGSKSTERLPG-----EPRGEEQIVPPGRQRARSSSVPRE 1165
                 +   P  SPA  G    ++ T R P      +P+G + + PP     R  + P  
Sbjct: 230  SRSLSSSATPLSSPARSGP--SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 287

Query: 1166 VLRLSLSSESELPSLPLFSEKSKTTKDSPQA-ARDGKRGVGSAGWPDRVTFRGQYTGHEY 1224
                S    +  PS P       + +  P   A    +   S G P   T +  ++    
Sbjct: 288  GPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP---TLQATHSFLPS 344

Query: 1225 HVLSPKAVPKGNGTVSC--------------PHCRPIRTQDAGGA------VTGDPLGPP 1264
              LSP A P      +               P   P+ T            +   P  PP
Sbjct: 345  PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404

Query: 1265 PADTLQCPLCGQVGSP--PEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPP 1322
            P+  +Q P       P  P A  P  A      A   +   S P+    S  A   P+ P
Sbjct: 405  PSPPVQAPFSPPASPPVSPSATPPSQAPPSLA-APPLQVPPSPPASPPMSPSATPPPQAP 463

Query: 1323 PGLW---YLATAPPAPAPPAFAYISSVPIMPYPPAAVY-YAPAGPTSAQPAAKWPPTASP 1378
            P L         PP  APPA A    +  +P PPA+    AP  P+++ P +   P A+P
Sbjct: 464  PPLAAPPLQLAKPPPQAPPALA-TPPLQALPSPPASFPGQAPFSPSASLPMS---PLATP 519

Query: 1379 PP 1380
            PP
Sbjct: 520  PP 521



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 139/572 (24%), Positives = 192/572 (33%), Gaps = 122/572 (21%)

Query: 866  PGPGVPPHPP--GTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETD 923
            P P   P PP  G + + S  S  ++ E S  + R P      GGG       +  P + 
Sbjct: 183  PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA----GGG-------LQRPASR 231

Query: 924  SGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATE 983
            S    S T   SP    P  R       GT   P   S P+     PK   +L P + T 
Sbjct: 232  S-LSSSATPLSSPARSGPSAR-------GTPRAPAHPSQPK-----PKGLQALRPPQVTP 278

Query: 984  PSTPRSQAQRYLSS-------PSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHK-----R 1031
            P    + A   LSS       PS P    AP  SL+ TL +  A P S+          +
Sbjct: 279  PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP-SLQ-TLPSPPATPPSQATTSLGSPTLQ 336

Query: 1032 ISEQPLPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQEEVSRLRLRL 1091
             +   LP+  +SP   P P A P    P    P                 +  + L + L
Sbjct: 337  ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 396

Query: 1092 EDSLHQPLQGSPTRPASA-FDRPARTRGRPADSPATWGSHYGSKSTERLPGEPRGEEQI- 1149
               L  P    P+ P  A F  PA     P+ +P +      +    ++P  P     + 
Sbjct: 397  ---LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 453

Query: 1150 ---VPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKRGVG- 1205
                PP +     ++ P ++ +    +   L + PL          SP A+  G+     
Sbjct: 454  PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL------QALPSPPASFPGQAPFSP 507

Query: 1206 SAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDPLGPPP 1265
            SA  P                +SP A P        P   P+        +   P  PP 
Sbjct: 508  SASLP----------------MSPLATPP-------PQAPPV----LAAPLLQVPPSPPA 540

Query: 1266 ADTLQCP-------------------LCGQVGSPPEADGPGSATSGAEKATTRRKASSTP 1306
            + TLQ P                          PP +  P S  SG + A     A+STP
Sbjct: 541  SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 600

Query: 1307 SPKQ---RSKQAGSSPRPPPGLWYLATAPPA----PAPP-AFAYISSVPIMPYPPA---- 1354
               +      + G++  PPP     A  P A    PAPP AF      P +P+PPA    
Sbjct: 601  EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP-LPWPPATGPG 659

Query: 1355 -----AVYYAPAGPTSAQPAAKWPPTASPPPA 1381
                    Y   GP SA PA   P    P P+
Sbjct: 660  SADGLCTIYETEGPESATPA---PGALDPGPS 688



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 114/494 (23%), Positives = 158/494 (31%), Gaps = 76/494 (15%)

Query: 861  AEAAPPGPGVP--PHPPGTKSAASHQ---------SSMTSLEGSGISERLPQKPLHRGGG 909
            A   P  P  P  P P G ++    Q          ++  L  S ++   P  P      
Sbjct: 250  ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAP 309

Query: 910  PHLEETWMASPETDSGFVGSETSRVSPLTQT-----PEHRLSHISTAGTLAQPFAASVPR 964
            P L+ T  + P T      + TS  SP  Q      P   LS ++T    A P  A  P 
Sbjct: 310  PSLQ-TLPSPPATPPS--QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 366

Query: 965  DGASYPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGS 1024
                 P A   L P     P  P + A   L +P  P     P+  ++   +   + P S
Sbjct: 367  QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP----PPSPPVQAPFSPPASPPVS 422

Query: 1025 EFEGHKRISEQPLPNKTISPPPAP------APAAAPLPCGPTETIPSFLLTRAGRDQAIC 1078
                    +   L    +  PP+P      +P+A P P  P       L       QA  
Sbjct: 423  PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 482

Query: 1079 ELQEEVSRLRLRLEDSLHQPLQGSPTRPAS-----AFDRPARTRGRPADSPATWGSHYGS 1133
             L                 PLQ  P+ PAS      F   A     P  +P        +
Sbjct: 483  ALATP--------------PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 528

Query: 1134 KSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDS 1193
                ++P  P     +  P R             RL+L+     P  P  S    +T   
Sbjct: 529  APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP--SRSPSSTLSG 586

Query: 1194 PQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPH--------CR 1245
            P  A     G  S+        RG  +G E       A P  +  ++  H          
Sbjct: 587  PDLA-----GHSSSATSTPEELRGYDSGPEG---GAAASPPPDAELAACHPAAWSRGPAP 638

Query: 1246 PIRTQDAGGAVTGDP--LGPPPADTLQCPLCGQVG------SPPEAD-GPGSATSGAEKA 1296
            P+  + A GA    P   GP  AD L C +    G      +P   D GP   TSG + A
Sbjct: 639  PLAFRGAPGAPLPWPPATGPGSADGL-CTIYETEGPESATPAPGALDPGPSPGTSGGKAA 697

Query: 1297 TTRRKASSTPSPKQ 1310
                  +S+ SPKQ
Sbjct: 698  AGAGAGASSRSPKQ 711



 Score = 39.7 bits (91), Expect = 0.021
 Identities = 61/210 (29%), Positives = 80/210 (38%), Gaps = 31/210 (14%)

Query: 1227 LSPKAVPKGNGTV--SCPHCRPIRTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSPPEAD 1284
            L+ +A   G  T+  S P   P RT     +  G+   PP  +T      G V SP  A 
Sbjct: 58   LAERAGGIGGATIPESAPRAGPTRTSRPPASGRGER-APPAKNTSP----GPVSSPGRAS 112

Query: 1285 G---PGSATS-----GAEKATTRRKASSTPSPKQRSKQAGS---SPRPPPGLWYLATAPP 1333
            G   PG          AE+   R KA  T +PK+ +  AG+   +  P PG     T  P
Sbjct: 113  GTTRPGPLGQKGLRISAEETVARGKA--TEAPKRSALSAGARRDTSGPTPG-----TPSP 165

Query: 1334 APAPPAFAYISSVPI-MPYPPAAVYYAPAGPTSAQPAAKWPPTASPPPARRHRHSIQLDL 1392
            A A  + A  + V +  P P A       GP  +  +A    T  P PA R R S    L
Sbjct: 166  AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 225

Query: 1393 -----GDLEELNKALSRAVQAAESVRSTTR 1417
                   L      LS   ++  S R T R
Sbjct: 226  QRPASRSLSSSATPLSSPARSGPSARGTPR 255



 Score = 33.1 bits (74), Expect = 2.0
 Identities = 59/254 (23%), Positives = 82/254 (32%), Gaps = 41/254 (16%)

Query: 815  PRQCPVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGKAEAAPPGPGVPPHP 874
            P   P QA  S G+P  +AT   +   P    A+       +       APP P  P  P
Sbjct: 319  PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP--PASP 376

Query: 875  PGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSETSRV 934
            P +  A     +  +L    +       P               SP   + F    +  V
Sbjct: 377  PLSPLATPSPQAPNALAVHLLQAPFSPPP---------------SPPVQAPFSPPASPPV 421

Query: 935  SPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATEPSTPRSQAQRY 994
            SP    P             A P  A+ P      P A   + P      +TP  QA   
Sbjct: 422  SPSATPPSQ-----------APPSLAAPPLQVPPSPPASPPMSPS-----ATPPPQAPPP 465

Query: 995  LSSPSGPLRQRAPNFSLERTLAAE----MAVPGSEFEGHKRISEQPLPNKTISPPPAPAP 1050
            L++P  PL+   P       LA      +  P + F G    S  P  +  +SP   P P
Sbjct: 466  LAAP--PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS--PSASLPMSPLATPPP 521

Query: 1051 AAAPLPCGPTETIP 1064
             A P+   P   +P
Sbjct: 522  QAPPVLAAPLLQVP 535


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 136/583 (23%), Positives = 195/583 (33%), Gaps = 132/583 (22%)

Query: 851  RDGHMSGLGKAEAAPPGPGV-PPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGG 909
            RD   +G      A   PG+  P PPG+       +   +L   G +  + +KPL    G
Sbjct: 5    RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTP-AALRVLGAAGAVGRKPLAERAG 63

Query: 910  PHLEETWMASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASY 969
                           G  G+     +P       R     +AGT ++  A+  P  G   
Sbjct: 64   ---------------GIGGATIPESAP-------RAGPTRSAGTSSRNPASRPPASG--- 98

Query: 970  PKARGSLIP-RRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFE- 1027
               RG   P  + T P    S  +   ++  GPL Q+    S E T+A   A    +   
Sbjct: 99   ---RGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSA 155

Query: 1028 ---GHKRISEQPLPNKTISPP--------------PAPAPAAAPLPCGPTETIPSFLLTR 1070
               G +R +  P P  T SP               P PAP+A P P  PTE         
Sbjct: 156  LSAGARRDTSGPTPG-TPSPAMARRSRAAGTEVGLPRPAPSARPRP--PTE--------- 203

Query: 1071 AGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASA--FDRPAR----TRGRPADSP 1124
             G  +++    E           S  +P   +  RP++     RPA     +   P  SP
Sbjct: 204  -GPRKSVSSASEH----------STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 252

Query: 1125 ATWGSHYGSKSTERLPG-----EPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPS 1179
            A  G    ++ T R P      +P+G + + PP     R  + P      S    +  PS
Sbjct: 253  ARSGP--SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 310

Query: 1180 LPLFSEKSKTTKDSP-------QAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAV 1232
              L S+   T   +P       Q A        S   P  +            + SP A 
Sbjct: 311  AALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQT----------LPSPPAT 360

Query: 1233 PKGNGTVSC--------------PHCRPIRTQ--DAGGAVTGDPLGPPPADTLQCPLCGQ 1276
            P    T S               P   P+ T    A  A+   PL  PP+     PL   
Sbjct: 361  PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 420

Query: 1277 VGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPA 1336
                P+A            A    +A  +P P    +   S P  PP     +  PP+ A
Sbjct: 421  ATPSPQAPNA--------LAVHLLQAPFSPPPSPPVQAPFSPPASPPVS--PSATPPSQA 470

Query: 1337 PPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPP 1379
            PP+ A     P +  PP+     P  P++  P    PP A+PP
Sbjct: 471  PPSLA----APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 509



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 141/578 (24%), Positives = 194/578 (33%), Gaps = 104/578 (17%)

Query: 866  PGPGVPPHPP--GTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETD 923
            P P   P PP  G + + S  S  ++ E S  + R P      GGG       +  P + 
Sbjct: 192  PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA----GGG-------LQRPASR 240

Query: 924  SGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATE 983
            S    S T   SP    P  R       GT   P   S P+     PK   +L P + T 
Sbjct: 241  S-LSSSATPLSSPARSGPSAR-------GTPRAPAHPSQPK-----PKGLQALRPPQVTP 287

Query: 984  PSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEM-AVPGSEFEGHKRISEQPLPNKTI 1042
            P    + A   LSS   PL   +P+ +L+      + A P S     +  +  PL   + 
Sbjct: 288  PRKDAAPALGPLSS--SPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP 345

Query: 1043 SPPPA----PAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQP 1098
            S PP+    P+P A P P   T ++ S  L           L    +            P
Sbjct: 346  SAPPSLQTLPSPPATP-PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 404

Query: 1099 LQGSPTRPASAFDRPARTRGRPA---------DSPATWGSHYGSKSTERLPGEPRGEEQI 1149
            LQ  P+ PAS    P  T    A          +P +       ++    P  P      
Sbjct: 405  LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 464

Query: 1150 VPPGRQRARSSSVPREVLRLSLSSESELPSL--------PLFSEKSKTTKDSPQAARDGK 1201
             PP +     ++ P +V     +S    PS         PL +   +  K  PQA     
Sbjct: 465  TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA 524

Query: 1202 RGVGSAGWPDRVTFRGQ--YTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGD 1259
                 A      +F GQ  ++      +SP A P        P   P+        +   
Sbjct: 525  TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP-------PQAPPV----LAAPLLQV 573

Query: 1260 PLGPPPADTLQCP-------------------LCGQVGSPPEADGPGSATSGAEKATTRR 1300
            P  PP + TLQ P                          PP +  P S  SG + A    
Sbjct: 574  PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 633

Query: 1301 KASSTPSPKQ---RSKQAGSSPRPPPGLWYLATAPPA----PAPP-AFAYISSVPIMPYP 1352
             A+STP   +      + G++  PPP     A  P A    PAPP AF      P +P+P
Sbjct: 634  SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP-LPWP 692

Query: 1353 PA---------AVYYAPAGPTSAQPAAKWPPTASPPPA 1381
            PA            Y   GP SA PA   P    P P+
Sbjct: 693  PATGPGSADGLCTIYETEGPESATPA---PGALDPGPS 727



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 121/520 (23%), Positives = 172/520 (33%), Gaps = 76/520 (14%)

Query: 829  PLEEATEKMVSMKPPGFQASLARDGHMSGLGKAEAAP-----PGPGVPPHPPGTKSAASH 883
            P +   + + +++PP  Q +  R      LG   ++P     P   +    P T  A  H
Sbjct: 269  PSQPKPKGLQALRPP--QVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH 326

Query: 884  QSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSPLTQT--- 940
             SS+T      ++  LP  P      P L+ T  + P T      + TS  SP  Q    
Sbjct: 327  SSSLTCQ----LATPLPLAPPSPSAPPSLQ-TLPSPPATPPS--QATTSLGSPTLQATHS 379

Query: 941  --PEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATEPSTPRSQAQRYLSSP 998
              P   LS ++T    A P  A  P      P A   L P     P  P + A   L +P
Sbjct: 380  FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 439

Query: 999  SGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTISPPPAP------APAA 1052
              P     P+  ++   +   + P S        +   L    +  PP+P      +P+A
Sbjct: 440  FSP----PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 495

Query: 1053 APLPCGPTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPAS---- 1108
             P P  P       L       QA   L                 PLQ  P+ PAS    
Sbjct: 496  TPPPQAPPPLAAPPLQLAKPPPQAPPALATP--------------PLQALPSPPASFPGQ 541

Query: 1109 -AFDRPARTRGRPADSPATWGSHYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVL 1167
              F   A     P  +P        +    ++P  P     +  P R             
Sbjct: 542  APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 601

Query: 1168 RLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVL 1227
            RL+L+     P  P  S    +T   P  A     G  S+        RG  +G E    
Sbjct: 602  RLTLALAPGPPPPP--SRSPSSTLSGPDLA-----GHSSSATSTPEELRGYDSGPEG--- 651

Query: 1228 SPKAVPKGNGTVSCPH--------CRPIRTQDAGGAVTGDP--LGPPPADTLQCPLCGQV 1277
               A P  +  ++  H          P+  + A GA    P   GP  AD L C +    
Sbjct: 652  GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL-CTIYETE 710

Query: 1278 G------SPPEAD-GPGSATSGAEKATTRRKASSTPSPKQ 1310
            G      +P   D GP   TSG + A      +S+ SPKQ
Sbjct: 711  GPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 750



 Score = 37.4 bits (85), Expect = 0.10
 Identities = 62/217 (28%), Positives = 82/217 (37%), Gaps = 36/217 (16%)

Query: 1227 LSPKAVPKGNGTV--SCPHCRPIRTQDAGGAVTGDPLGPPPADTL--QCPLC-----GQV 1277
            L+ +A   G  T+  S P   P R+    G  + +P   PPA     + P       G V
Sbjct: 58   LAERAGGIGGATIPESAPRAGPTRS---AGTSSRNPASRPPASGRGERAPPAKNTSPGPV 114

Query: 1278 GSPPEADG---PGSATS-----GAEKATTRRKASSTPSPKQRSKQAGS---SPRPPPGLW 1326
             SP  A G   PG          AE+   R KA  T +PK+ +  AG+   +  P PG  
Sbjct: 115  SSPGRASGTTRPGPLGQKGLRISAEETVARGKA--TEAPKRSALSAGARRDTSGPTPG-- 170

Query: 1327 YLATAPPAPAPPAFAYISSVPI-MPYPPAAVYYAPAGPTSAQPAAKWPPTASPPPARRHR 1385
               T  PA A  + A  + V +  P P A       GP  +  +A    T  P PA R R
Sbjct: 171  ---TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227

Query: 1386 HSIQLDL-----GDLEELNKALSRAVQAAESVRSTTR 1417
             S    L       L      LS   ++  S R T R
Sbjct: 228  PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264



 Score = 33.1 bits (74), Expect = 2.0
 Identities = 59/254 (23%), Positives = 82/254 (32%), Gaps = 41/254 (16%)

Query: 815  PRQCPVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGKAEAAPPGPGVPPHP 874
            P   P QA  S G+P  +AT   +   P    A+       +       APP P  P  P
Sbjct: 358  PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP--PASP 415

Query: 875  PGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSETSRV 934
            P +  A     +  +L    +       P               SP   + F    +  V
Sbjct: 416  PLSPLATPSPQAPNALAVHLLQAPFSPPP---------------SPPVQAPFSPPASPPV 460

Query: 935  SPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATEPSTPRSQAQRY 994
            SP    P             A P  A+ P      P A   + P      +TP  QA   
Sbjct: 461  SPSATPPSQ-----------APPSLAAPPLQVPPSPPASPPMSPS-----ATPPPQAPPP 504

Query: 995  LSSPSGPLRQRAPNFSLERTLAAE----MAVPGSEFEGHKRISEQPLPNKTISPPPAPAP 1050
            L++P  PL+   P       LA      +  P + F G    S  P  +  +SP   P P
Sbjct: 505  LAAP--PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS--PSASLPMSPLATPPP 560

Query: 1051 AAAPLPCGPTETIP 1064
             A P+   P   +P
Sbjct: 561  QAPPVLAAPLLQVP 574


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 160/636 (25%), Positives = 212/636 (33%), Gaps = 123/636 (19%)

Query: 828  APLEEATEKMVSMKP-PGFQASLARDGHMSGLGKAEAAPPGPGVPPH--PPGTKSAASHQ 884
            +P+  + E ++   P PG     AR G      K  + PP PG P    PPGT      Q
Sbjct: 719  SPMSRSQEYLLDEGPAPGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQ 778

Query: 885  SSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSP--LTQTPE 942
            +   +  GS      PQ      GGPH      A  +     +      +SP  L Q+P 
Sbjct: 779  TPTKTRPGS------PQAL----GGPHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPT 828

Query: 943  HRLSHISTAGTLAQPFAASV--PRDGASYPKARGS-----LIPRRATEPSTPRSQAQ--- 992
            HR      A  L QP    V     G + P    +     L P    EP  P+ +A    
Sbjct: 829  HR----GFAYVLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAHSLN 884

Query: 993  RYLSSPSGPLRQR-------APNFSLERTLAAEMAV---PGSEFEGHKRISEQPLPNKTI 1042
            RY +S S P R          P  +++R +    +V    G++   ++  S    P K  
Sbjct: 885  RYAASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRKKG 944

Query: 1043 SPPPAPAPAAAPL--------PCGPTETIPSFLLTRAGRDQAI-------CELQEEVSRL 1087
             PPP P  +++ L        P    E     L  RA   +A              V  +
Sbjct: 945  PPPPPPKRSSSALASANLADEPVPDAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSI 1004

Query: 1088 RLRLEDS--------LHQPLQGSPTRPASAFDRPART---------------------RG 1118
               LE S          +P +G PT P  A   P R                      R 
Sbjct: 1005 AAMLELSSIGGGGRAARRPPEGHPT-PRPASPEPGRVATVLASVKHKEAIGPGGEVVNRR 1063

Query: 1119 RPADSPATWGSHYGSKSTERL-PGEPRGEEQIVPPG--RQRARSSSVPREVLRLSLSSES 1175
            R    P T     G  +T R  PGE       V  G  RQR R  S            E+
Sbjct: 1064 RTLSGPVT-----GLLATARRGPGESADPGPFVEDGTGRQRPRGPS----------KGEA 1108

Query: 1176 ELPSLPLFS-EKSKTTKDSPQAARDGKRGVGSA-GWPDRVTFRGQYTGHEYHVLSPKAVP 1233
             +   PL   E S T K   +A ++ +  V       D V  R +    E     P  + 
Sbjct: 1109 GVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLS 1168

Query: 1234 ---KGNGTVSCPHCRPIRTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSPPEADGPGSAT 1290
                G GTV     RP   Q       G P  PPP    + P       PP     G A 
Sbjct: 1169 VYHNGTGTV---RRRPASEQ------AGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEAR 1219

Query: 1291 SGAEKATTRRKASSTPSPKQRSKQAGSS---PRPPPGLWYLATAPPAPAPPAFAYISSVP 1347
              A+   + +   + P PK +     +S   P P PG   +  A   P PP        P
Sbjct: 1220 KPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTP-PPVSPKPPPPP 1278

Query: 1348 IMPYPPAAVYYAP---AGPTSAQPAAKWPPTASPPP 1380
              P P  AV   P   AGP+ A   A+ PP A   P
Sbjct: 1279 TAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKP 1314



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 53/180 (29%), Positives = 70/180 (38%), Gaps = 28/180 (15%)

Query: 1232 VPKGNGTVSCPHCRPIRTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSPPEADGPGSATS 1291
            VPK  G+ + P  + +     G        G PP      P+  +   PP A  P  A +
Sbjct: 1236 VPKLQGSPT-PTSKKVPLPGPGSPEVKRAHGTPP------PVSPKPPPPPTAPKPVKAVA 1288

Query: 1292 GAEKATTRRKASSTPSPKQRSKQA-GSSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMP 1350
            G    +     S  PSP ++   A    P  PP L      PP+P  PA      VP  P
Sbjct: 1289 GLPSGSAG--PSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPAL----HVPAKP 1342

Query: 1351 YPPAAVYYAPAGPTSAQPAAKWPPTASPPPARRHRHSIQLDLGDLEELNKALSRAVQAAE 1410
               AA   A A   +A PA   P  ASP  + R +         LEE +  L+ A+QA E
Sbjct: 1343 PRAAA---AAAAAAAAPPAP--PEGASPGDSARQK---------LEETSACLAAALQAVE 1388



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 81/340 (23%), Positives = 106/340 (31%), Gaps = 49/340 (14%)

Query: 990  QAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTISPPPAPA 1049
            Q   Y     GPLR++AP  SLE  +A E   P        +  +      +       A
Sbjct: 606  QKAEYAKYEGGPLRRKAPQ-SLE-VMAIESPPPPEPTPADCQSPKMTTFQDSELSDELQA 663

Query: 1050 PAAAPLPCGPTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASA 1109
                P   GPT   PS  L    R       Q+     R R   S  + L   P  P+S 
Sbjct: 664  AMTGPAEVGPTTEKPSSHLPPTPRATT---RQDSSLGGRARHMSSSQELLGDGPPGPSSP 720

Query: 1110 FDR---------PARTRGRPADSPATWGSHYGSKSTERLPGEPRGEEQIVPPGRQRARSS 1160
              R         PA         P   G      S   +PG+PR   Q++PPG       
Sbjct: 721  MSRSQEYLLDEGPAPGTPPREARPGRHGHSIKRASVPPVPGKPR---QVLPPGTSHFTPP 777

Query: 1161 SVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYT 1220
              P                       +KT   SPQA   G  G   A    +V    Q  
Sbjct: 778  QTP-----------------------TKTRPGSPQAL-GGPHGPAPA--TAKVKPTPQLL 811

Query: 1221 GHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSP 1280
                  +SP+++P+        +  P   +   G     P  PPP  T    LC     P
Sbjct: 812  PPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGP-APPPVPTAVPTLC----LP 866

Query: 1281 PEADG-PGSATSGAEKATTRRKASSTPSPKQRSKQAGSSP 1319
            PEAD  PG     A        + S P   +    A + P
Sbjct: 867  PEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGP 906



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 134/616 (21%), Positives = 198/616 (32%), Gaps = 119/616 (19%)

Query: 872  PHPPGTKSAASHQSSMTSLEGSGISERLPQK--------PLHRGGGPHLEETWMASPETD 923
            P PP    A      MT+ + S +S+ L           P       HL  T  A+   D
Sbjct: 634  PPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHLPPTPRATTRQD 693

Query: 924  SGFVG-----SETSRV---------SPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASY 969
            S   G     S +  +         SP++++ E+ L      GT   P  A   R G S 
Sbjct: 694  SSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGT--PPREARPGRHGHSI 751

Query: 970  PKARGSLIPRRA-----------TEPSTP---RSQAQRYLSSPSGPLRQRA---PNFSL- 1011
             +A    +P +            T P TP   R  + + L  P GP    A   P   L 
Sbjct: 752  KRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLL 811

Query: 1012 ---ERTLAAEMAVPGSEFEGHKRISEQPLPNKT----ISPPPAPAPAAAPLPCGPTETIP 1064
               ER ++           G   +  QP+  +       P P P P A P  C P E   
Sbjct: 812  PPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEADA 871

Query: 1065 --------SFLLTRAGRDQAICELQE----------EVSRLRLRLEDSLHQP--LQGSPT 1104
                    +  L R     +  E  E             + R+    S+  P     +  
Sbjct: 872  EPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVN 931

Query: 1105 RPASAFDRPARTRGRPADSPATWGSHYGSKSTERLP-GEPRGEEQIVPPGRQRARSSSVP 1163
            R  S   RP R +G P   P    S   S +    P  +   E+ ++    Q  R+S + 
Sbjct: 932  RSQSFAVRP-RKKGPPPPPPKRSSSALASANLADEPVPDAEPEDGLLGVRAQCRRASDLA 990

Query: 1164 REVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHE 1223
              V   S  S   + ++   S      + + +          ++  P RV        H+
Sbjct: 991  GSVDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEGHPTPRPASPEPGRVATVLASVKHK 1050

Query: 1224 YHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDPLGPPPADTL-----QCPLCGQVG 1278
              +     V     T+S P    + T   G   + DP GP   D       + P  G+ G
Sbjct: 1051 EAIGPGGEVVNRRRTLSGPVTGLLATARRGPGESADP-GPFVEDGTGRQRPRGPSKGEAG 1109

Query: 1279 --SPPEADGPGSATSGAEKATTRRKASSTPS--------------PKQRSKQAGSSPRPP 1322
               PP A    SAT    K   R K +   +              PK + ++AG  P PP
Sbjct: 1110 VEGPPLAKVEASATL---KRRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPP 1166

Query: 1323 PGLWYLATA------------------PPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPT 1364
              +++  T                   PP PA P    ++ +P +P PP      PA P 
Sbjct: 1167 LSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLP-PPEGEARKPAKP- 1224

Query: 1365 SAQPAAKWPPTASPPP 1380
               P +  P    P P
Sbjct: 1225 ---PVSPKPVLTQPVP 1237


>gi|209862789 microtubule associated monoxygenase, calponin and LIM
            domain containing 3 isoform 1 [Homo sapiens]
          Length = 2002

 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 163/734 (22%), Positives = 245/734 (33%), Gaps = 122/734 (16%)

Query: 728  EVSSGNSEVEDRPQDP---LARLRHKE-LQMEQVYHGLMERYLSV-KSLPEAMRMEEEEE 782
            E+     E E+ P+ P   L  +  KE +++  +  G  E  L   KS       EEEEE
Sbjct: 939  EMEEEGEEEEEEPRLPPSDLGGVPWKEAVRIHALLKGKSEEELEASKSFGPGNEEEEEEE 998

Query: 783  GEEEEEE------------EGGGDSLEVDGVAATPGKAEA----TRVLPRQ-----CPVQ 821
             E EEEE            E G   L+    AA P + +A    T +  R+      P  
Sbjct: 999  EEYEEEEEEDYDEEEEESSEAGNQRLQQVMHAADPLEIQADVHWTHIREREEEERMAPAS 1058

Query: 822  AEKSHGAPLEE-ATEKMVSMKPPGFQASLARDGHMSGLGKA----EAAPPGPGVPPHPPG 876
               + GAPL+E   E+ V  +P   +   A DG     G      +     P        
Sbjct: 1059 ESSASGAPLDENDLEEDVDSEPAEIEGEAAEDGDPGDTGAELDDDQHWSDSPSDADRELR 1118

Query: 877  TKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSP 936
                A  ++ +  L  S   E+LP  P H+  GP    + + SP+             S 
Sbjct: 1119 LPCPAEGEAEL-ELRVSEDEEKLPASPKHQERGPSQATSPIRSPQE------------SA 1165

Query: 937  LTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATEPSTPRSQAQRYLS 996
            L   P H     ST G    P  A+        P+ R  L P        P++ A   L 
Sbjct: 1166 LLFIPVH---SPSTEGPQLPPVPAATQEKS---PEER--LFPEPLLPKEKPKADAPSDLK 1217

Query: 997  SPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTIS-PPPAPAPAAAPL 1055
            +   P+R +       RT  +    PG         S QP P    S PPP+P P  +  
Sbjct: 1218 AVHSPIRSQPVTLPEARTPVS----PG---------SPQPQPPVAASTPPPSPLPICSQP 1264

Query: 1056 PCGPTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPAR 1115
                  T+PS   +      A  +    ++ L ++ +      L GSP     A  R   
Sbjct: 1265 QPSTEATVPSPTQSPIRFQPAPAKTSTPLAPLPVQSQSDTKDRL-GSPLAVDEALRR--- 1320

Query: 1116 TRGRPADSPATWGSHYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSES 1175
                     +     +  KS      E R    + P  R +    S P            
Sbjct: 1321 ---------SDLVEEFWMKS-----AEIRRSLGLTPVDRSKGPEPSFP------------ 1354

Query: 1176 ELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKG 1235
              P+    S KS + + SPQ   +G   +     P R+    +  G    + +P++ P  
Sbjct: 1355 -TPAFRPVSLKSYSVEKSPQ--DEGLHLLKPLSIPKRLGL-PKPEGEPLSLPTPRS-PSD 1409

Query: 1236 NGTVSCPHCRPIRTQDAGGAVTGD-----PLGPPPADTLQCPLCGQVGSPPEADGPGSAT 1290
                S    R   +  +G  + G       LG    +T    +     SPP    PG   
Sbjct: 1410 RELRSAQEERRELSSSSGLGLHGSSSNMKTLGSQSFNTSDSAMLTPPSSPPPPPPPGE-- 1467

Query: 1291 SGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAP---PAFAYISSVP 1347
               E AT RRK       ++    A   P P P  W      PA  P      +++ SV 
Sbjct: 1468 ---EPATLRRKL------REAEPNASVVPPPLPATWMRPPREPAQPPREEVRKSFVESVE 1518

Query: 1348 IMPYPPAA--VYYAPAGPTSAQPAAKWPPTASPPPARRHRHSIQLDLGDLEELNKALSRA 1405
             +P+       Y      +S Q     PP+  P P +     +  + G L  L   L   
Sbjct: 1519 EIPFADDVEDTYDDKTEDSSLQEKFFTPPSCWPRPEKPRHPPLAKENGRLPALEGTLQPQ 1578

Query: 1406 VQAAESVRSTTRQM 1419
             +    V +  +++
Sbjct: 1579 KRGLPLVSAEAKEL 1592



 Score = 38.9 bits (89), Expect = 0.036
 Identities = 102/455 (22%), Positives = 162/455 (35%), Gaps = 101/455 (22%)

Query: 912  LEETWMASPET--DSGFVGSETSR-VSPLTQTPEHRLSHISTAGTLAQPFAASVPR-DGA 967
            +EE WM S E     G    + S+   P   TP  R   + +      P    +      
Sbjct: 1324 VEEFWMKSAEIRRSLGLTPVDRSKGPEPSFPTPAFRPVSLKSYSVEKSPQDEGLHLLKPL 1383

Query: 968  SYPKARGSLIPRRATEP---STPRSQAQRYLSSPSGPLRQRAPNFSLE--------RTLA 1016
            S PK  G  +P+   EP    TPRS + R L S     R+ + +  L         +TL 
Sbjct: 1384 SIPKRLG--LPKPEGEPLSLPTPRSPSDRELRSAQEERRELSSSSGLGLHGSSSNMKTLG 1441

Query: 1017 AEM------------------AVPGSEFEGHKRISEQPLPNKTISPPPAPAPAAAPLPCG 1058
            ++                     PG E    +R   +  PN ++ PPP PA    P P  
Sbjct: 1442 SQSFNTSDSAMLTPPSSPPPPPPPGEEPATLRRKLREAEPNASVVPPPLPATWMRP-PRE 1500

Query: 1059 PTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTR-----PASAFDRP 1113
            P +        R    ++  E  EE+      +ED+     + S  +     P S + RP
Sbjct: 1501 PAQP------PREEVRKSFVESVEEIP-FADDVEDTYDDKTEDSSLQEKFFTPPSCWPRP 1553

Query: 1114 ARTRGRPADS-----PATWGSHYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLR 1168
             + R  P        PA  G+    K    L      E + +   R RAR  SV  + LR
Sbjct: 1554 EKPRHPPLAKENGRLPALEGTLQPQKRGLPLVS---AEAKELAEERMRAREKSVKSQALR 1610

Query: 1169 LSLSSE-SELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVL 1227
             +++ + S +  + L S   +  K S   ++  +R   S   P R T RG     E   L
Sbjct: 1611 DAMARQLSRMQQMELASGAPRPRKASSAPSQGKERRPDS---PTRPTLRGS----EEPTL 1663

Query: 1228 SPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSPPEADGPG 1287
              +A                         T + +  PP+D+         G P   DG  
Sbjct: 1664 KHEA-------------------------TSEEVLSPPSDS---------GGP---DGSF 1686

Query: 1288 SATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPP 1322
            +++ G+   + +R +  +P   ++ K++    RPP
Sbjct: 1687 TSSEGSSGKSKKRSSLFSPRRNKKEKKSKGEGRPP 1721


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 57.8 bits (138), Expect = 8e-08
 Identities = 138/581 (23%), Positives = 205/581 (35%), Gaps = 127/581 (21%)

Query: 824  KSHGAPLEEATEKMVSMKPPGF---QASLARDGHMSGLGKAEAAPPGPGVPPHPPGTKSA 880
            + HG+P E           PG    QA  A       + +  A+P  P   P P  + ++
Sbjct: 572  EEHGSPPEPLFPNDWDPLDPGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPFPAQSSAS 631

Query: 881  ASHQSSMTSLEGSGISERLPQKPLH----RGGGPHLEETWM----ASPETDSGFVGSETS 932
             S   S    EG G  E L   P      RG  P +EE       +SP  DS  +G   S
Sbjct: 632  GSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEEGSSPGEDSSSLGGGPS 691

Query: 933  RVSPLT---------------------------------QTPEHRLSHISTAGTLAQ-PF 958
            R  PL                                    PE   S  +  G+LA  P 
Sbjct: 692  RRGPLPCPLCSREGACSCLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAERGSLADLPM 751

Query: 959  A--ASVPRD------GASYPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFS 1010
            A  AS P +      GA+ P+  G   P     P  P        +SP  P    +P   
Sbjct: 752  APPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSG 811

Query: 1011 L--------------ERTLAAEMAVPG---SEFEGHKRISEQPLPNKTISPPPAPAPAAA 1053
            L              E   + E A PG   +E EG  R    P P    +P P P P   
Sbjct: 812  LSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPEPPDPGAPRPPPDPGPL 871

Query: 1054 PLPCGPTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRP 1113
            PLP GP E  P+F++ +   +Q +  L+E+V+R  L               + A+A +  
Sbjct: 872  PLP-GPREK-PTFVV-QVSTEQLLMSLREDVTRNLL-------------GEKGATARETG 915

Query: 1114 ARTRGRPADSPATWGSHYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSS 1173
             R  GR            G  + E++PG  R +  ++  G+Q A S S+P   + +  + 
Sbjct: 916  PRKAGR------------GPGNREKVPGLNR-DPTVLGNGKQ-APSLSLPVNGVTVLENG 961

Query: 1174 ESELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTG--------HEYH 1225
            +   P +              +AA +G   +GS    ++V   G+ T             
Sbjct: 962  DQRAPGI------------EEKAAENG--ALGSPEREEKVLENGELTPPRREEKALENGE 1007

Query: 1226 VLSPKAVPK--GNGTVSCPHCRPIRTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSPPEA 1283
            + SP+A  K   NG ++ P      +++ G     +   PP     + P  G     PE+
Sbjct: 1008 LRSPEAGEKVLVNGGLTPPKSEDKVSENGGLRFPRNTERPPETGPWRAP--GPWEKTPES 1065

Query: 1284 DGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPG 1324
             GP + T G     T  + +  PS    S+  G +   P G
Sbjct: 1066 WGP-APTIGEPAPETSLERAPAPSAVVSSRNGGETAPGPLG 1105



 Score = 38.5 bits (88), Expect = 0.047
 Identities = 43/124 (34%), Positives = 47/124 (37%), Gaps = 20/124 (16%)

Query: 1262 GPPPADTLQCPLCGQVGSP---PEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSS 1318
            GP     L CPLC + G+    P   G   A  G   A         P P +      SS
Sbjct: 689  GPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGGHPAL------GCPHPPEDD----SS 738

Query: 1319 PRPPPG-LWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTAS 1377
             R   G L  L  APPA APP F      P+M    AA  Y   GP  A P    PP A 
Sbjct: 739  LRAERGSLADLPMAPPASAPPEFLD----PLMG--AAAPQYPGRGPPPAPPPPPPPPRAP 792

Query: 1378 PPPA 1381
              PA
Sbjct: 793  ADPA 796



 Score = 34.3 bits (77), Expect = 0.89
 Identities = 40/149 (26%), Positives = 50/149 (33%), Gaps = 34/149 (22%)

Query: 1233 PKGNGTVSCP--------HCRPIRTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSPPEAD 1284
            P   G + CP         C P+   DA     G P        L CP       PPE D
Sbjct: 690  PSRRGPLPCPLCSREGACSCLPLERGDAVAGWGGHP-------ALGCP------HPPEDD 736

Query: 1285 GPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPR-----PPPGLWYLATAPPAPAPPA 1339
                A  G+         +S P          ++P+     PPP       APP P PP 
Sbjct: 737  SSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPP-------APPPPPPPP 789

Query: 1340 FAYISSVPIMPYPPAAVYYAPAGPTSAQP 1368
             A        P PP+AV    +G +S  P
Sbjct: 790  RAPADPAA-SPDPPSAVASPGSGLSSPGP 817



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 38/151 (25%), Positives = 49/151 (32%), Gaps = 29/151 (19%)

Query: 780 EEEGEEEEEEEGGGDSLEVDGVAATPG--------KAEATRVLPRQ-------------- 817
           EEE EEEE    G DS  + G  +  G        +  A   LP +              
Sbjct: 668 EEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGGHPAL 727

Query: 818 -CPVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGKA------EAAPPGPGV 870
            CP   E       E  +   + M PP        D  M              APP P  
Sbjct: 728 GCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPP 787

Query: 871 PPHPPGTKSAASHQSSMTSLEGSGISERLPQ 901
           PP  P   +A+    S  +  GSG+S   P+
Sbjct: 788 PPRAPADPAASPDPPSAVASPGSGLSSPGPK 818



 Score = 31.6 bits (70), Expect = 5.8
 Identities = 69/304 (22%), Positives = 95/304 (31%), Gaps = 52/304 (17%)

Query: 791  GGGDSLEVDGVAATPGKAEATRVLPRQCPVQAEKSHGAPLEEATEKMVSMKPPGFQASLA 850
            GGG      GV A  G  + TR  P   P+        P  EA  + +   PP  +  +A
Sbjct: 1153 GGGPG---SGVDAKAGWVDNTRPQPPPPPLP-------PPPEAQPRRLEPAPPRARPEVA 1202

Query: 851  RDGHMSGLGK---AEAAPPGPGVPPHPPGTKSAASH----------QSSMTSLEGSGISE 897
             +G           + A  G G PP P                    S       S +S 
Sbjct: 1203 PEGEPGAPDSRAGGDTALSGDGDPPKPERKGPEMPRLFLDLGPPQGNSEQIKARLSRLSL 1262

Query: 898  RLPQKPL--HRGGGPHLEETWMASPETDSGFVGSETSRVS---PLTQTPEHRLSHISTAG 952
             LP   L    G GP     W  +   D+G  G E        P  +  E          
Sbjct: 1263 ALPPLTLTPFPGPGPR-RPPWEGA---DAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDE 1318

Query: 953  TLAQPFAASVPRDGASYPKARGSLIPRRATEPSTPRSQAQR-YLSSPSGPLRQRAPNFSL 1011
              A P AA+ PR      +AR + +P   +      ++  R  L SP G           
Sbjct: 1319 EAAAPGAAAGPRGPG---RARAAPVPVVVSSADADAARPLRGLLKSPRGADEPEDSELER 1375

Query: 1012 ERTLAA----------EMAVPGSEFEGHKRISEQPLPNKTISPPPAPAPAAAPLPCGPTE 1061
            +R + +          +   P +E      +S Q  P     P   PAP   P P  P +
Sbjct: 1376 KRKMVSFHGDVTVYLFDQETPTNE------LSVQAPPEGDTDPSTPPAPPTPPHPATPGD 1429

Query: 1062 TIPS 1065
              PS
Sbjct: 1430 GFPS 1433


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 73/294 (24%), Positives = 100/294 (34%), Gaps = 46/294 (15%)

Query: 1090 RLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLPGEPRGEEQI 1149
            R   S    L   P+RP     RP  +   P + P   G   G       P   R E + 
Sbjct: 404  RFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGGGGGGG-----PSPEREEVRT 458

Query: 1150 VPPGRQRARSSSVPREVLRLSL--SSESELPSLPLFSEKSKTTKDSPQAARDGKRGVGSA 1207
             P     ARS S   E    S+  +  S L S      K + +K S  A+   +    S+
Sbjct: 459  SPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSS 518

Query: 1208 GWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSC-PHCRPIRTQDAGGAVTGDPLGPPPA 1266
                 +    + TG E        VP G+G   C P   P   +D     +G+P      
Sbjct: 519  -----MVLGARDTGSE--------VPSGSGHGPCTPPPAPANFEDVAPTGSGEP------ 559

Query: 1267 DTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLW 1326
                    G     P+A+G   A+            SS    +      G SP P P   
Sbjct: 560  --------GATRESPKANGQNQASP----------CSSGDDMEISDDDRGGSPPPAPTPP 601

Query: 1327 YLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPPP 1380
                 PP P PP   Y++S+P+   P    Y  P  P    P  ++PP   PPP
Sbjct: 602  QQPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRP-DGPPPPEYPPPPPPPP 654



 Score = 44.3 bits (103), Expect = 9e-04
 Identities = 96/449 (21%), Positives = 143/449 (31%), Gaps = 62/449 (13%)

Query: 30   KRDVDRSSSQSWEEERLFPNATSPELLEDFRLAQQHLPPLEWDPHPQPDGHQDSESGETS 89
            KR      S++ EE+R  P+  + E  +D    ++   P    P  +P   +D E G+T 
Sbjct: 896  KRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGR--PGTKPP-KRDEERGKTQ 952

Query: 90   GEEAEAEDVDSPA------SSHEPLAWLPQQGRQLDMTEEEPDGTLGSLEVEEAGESSSR 143
            G+  ++  +DS        SS E      ++  + +  EE  D T    EV +  +  S 
Sbjct: 953  GKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESD 1012

Query: 144  LGYEAGLSLEGHGNTSPMALGHGQARGWVASGEQASGDKLSEHSEVNPSVELSPARSWSS 203
               +  L  +  G     +     +    +S   +S    S  S    S E        +
Sbjct: 1013 SSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPA 1072

Query: 204  GTVSLDHPSDSLDSTWEGETDGPQPTALAETLPEGPSHHLLSPDGRTGGSVARATPMEFQ 263
               S   P   +        + P P  +A + P  P     +   R  G    + P    
Sbjct: 1073 ALPSASPPPREVPVPTPAPVEVPVPERVAGS-PVTPLPEQEASPARPAGPTEESPPSAPL 1131

Query: 264  DSSAPPAQSPQHATDRWRRETTRFFCPQPKEHIWKQTKTSPKPLPSRFIGSISPLNPQPR 323
                PPA  P  A             P+P E         P P   R   S S +   P 
Sbjct: 1132 RPPEPPAGPPAPA-------------PRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPA 1178

Query: 324  PTRQGRPLPRQGATLAGRSSSNAPK-YGRGQLNYPLPDFSKV---------------GPR 367
            P  +  P     A   G +S  AP+   R   N PL   S V               G R
Sbjct: 1179 P--EPPPATPPQAKFPGPASRKAPRGVERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGR 1236

Query: 368  VRFPKDESYRPPKSRS---------HNRKPQAPARPLIFKS-----------PAEIVQEV 407
             R  ++E   P                 +   PA P +  S           P  ++  +
Sbjct: 1237 GRLTEEEEAEPGTEVDLAVLADLALTPARRGLPALPAVEDSEATETSDEAERPRPLLSHI 1296

Query: 408  LLSSGEAALAKDTPPAHPITRVPQEFQTP 436
            LL    A   K TPPA P  R P+    P
Sbjct: 1297 LLEHNYALAVKPTPPA-PALRPPEPVPAP 1324



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 57/256 (22%), Positives = 85/256 (33%), Gaps = 46/256 (17%)

Query: 1137 ERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQA 1196
            E+  GEP G     PP R   R  +  +     +L SE E  S    SEK +   +  + 
Sbjct: 928  EKEAGEP-GRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEE 986

Query: 1197 ARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAV 1256
              D +  V +      V+      G +              + S   C      D     
Sbjct: 987  DEDREEAVDTTKKETEVS-----DGEDEE------------SDSSSKCSLYADSDGENDS 1029

Query: 1257 TGDPLGPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAG 1316
            T D                +  S   +    S++S +  +++  ++SS    ++    A 
Sbjct: 1030 TSD---------------SESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAAL 1074

Query: 1317 SSPRPPPGLWYLATAPPAPAP---PAFAYISSVPIMPYPPAAVYYA-PAGPTSAQPAA-- 1370
             S  PPP         P PAP   P    ++  P+ P P      A PAGPT   P +  
Sbjct: 1075 PSASPPPR----EVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAP 1130

Query: 1371 ---KWPPTASPPPARR 1383
                 PP   P PA R
Sbjct: 1131 LRPPEPPAGPPAPAPR 1146



 Score = 36.6 bits (83), Expect = 0.18
 Identities = 88/399 (22%), Positives = 129/399 (32%), Gaps = 64/399 (16%)

Query: 695  GQAPMPAIKTSCPEPATTTAAASTGPCPLHVNVEVSSGNSEVEDRPQDPLARLRHKELQM 754
            G   +P+ K    EP+  + A+           E    + E E    +P  R   K  + 
Sbjct: 886  GALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEP-GRPGTKPPKR 944

Query: 755  EQVY---HGLMERYLSVKSLPEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATPGKAEAT 811
            ++      G   +  ++ S  E    E   E +EE++EE   D    + V  T  + E  
Sbjct: 945  DEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEV- 1003

Query: 812  RVLPRQCPVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGKAEAAPPGPGVP 871
                         S G   E  +    S+           DG       +E++       
Sbjct: 1004 -------------SDGEDEESDSSSKCSLYADS-------DGENDSTSDSESSSSSSSSS 1043

Query: 872  PHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSET 931
                 + S++S  SS +S E     ER    P      P   E  + +P      V  E 
Sbjct: 1044 SSSSSSSSSSSSSSSESSSEDEEEEERPAALP---SASPPPREVPVPTPAPVEVPV-PER 1099

Query: 932  SRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATE-PSTPRSQ 990
               SP+T  PE   S    AG   +           S P A     P R  E P+ P + 
Sbjct: 1100 VAGSPVTPLPEQEASPARPAGPTEE-----------SPPSA-----PLRPPEPPAGPPAP 1143

Query: 991  AQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTISPPPA--- 1047
            A R    PS P+    P     +T++               I   P P    + PP    
Sbjct: 1144 APRPDERPSSPIPLLPPPKKRRKTVS------------FSAIEVVPAPEPPPATPPQAKF 1191

Query: 1048 PAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQEEVSR 1086
            P PA+   P G   TI +  L  A     +    EEVSR
Sbjct: 1192 PGPASRKAPRGVERTIRNLPLDHA---SLVKSWPEEVSR 1227



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 77/318 (24%), Positives = 107/318 (33%), Gaps = 49/318 (15%)

Query: 767  SVKSLPEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATPGKAEATRVLPRQCPVQAEKSH 826
            S  S   +     E   E+EEEEE           AA P  +   R +P   P       
Sbjct: 1046 SSSSSSSSSSSSSESSSEDEEEEERP---------AALPSASPPPREVPVPTP------- 1089

Query: 827  GAPLEEATEKMVSMKP----PGFQASLARDGHMSGLGKAEAAPPG-PGVPPHPPGTKSAA 881
             AP+E    + V+  P    P  +AS AR       G  E +PP  P  PP PP    A 
Sbjct: 1090 -APVEVPVPERVAGSPVTPLPEQEASPARPA-----GPTEESPPSAPLRPPEPPAGPPAP 1143

Query: 882  SHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPET------DSGFVGSETSRVS 935
            + +        S     LP     R          + +PE        + F G   SR +
Sbjct: 1144 APRPDERP---SSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGP-ASRKA 1199

Query: 936  PLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATEPSTPRSQAQRYL 995
            P       R   +  A +L + +   V R G S    RG L      EP T    A    
Sbjct: 1200 PRGVERTIRNLPLDHA-SLVKSWPEEVSRGGRSRAGGRGRLTEEEEAEPGTEVDLAV-LA 1257

Query: 996  SSPSGPLRQRAPNF-SLERTLAAEMAVPGSE---------FEGHKRISEQPLPNKTISPP 1045
                 P R+  P   ++E + A E +               E +  ++ +P P      P
Sbjct: 1258 DLALTPARRGLPALPAVEDSEATETSDEAERPRPLLSHILLEHNYALAVKPTPPAPALRP 1317

Query: 1046 PAPAPAAAPLPCGPTETI 1063
            P P PA A L   P + +
Sbjct: 1318 PEPVPAPAALFSSPADEV 1335



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 41/138 (29%), Positives = 48/138 (34%), Gaps = 41/138 (29%)

Query: 1272 PLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATA 1331
            PL  Q  SP    GP                 S PS   R       P PP G       
Sbjct: 1107 PLPEQEASPARPAGP--------------TEESPPSAPLR------PPEPPAG------- 1139

Query: 1332 PPAPAP-PAFAYISSVPIMPYP----------PAAVYYAPAGPTSAQPAAKWPPTAS--- 1377
            PPAPAP P     S +P++P P             V  AP  P +  P AK+P  AS   
Sbjct: 1140 PPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGPASRKA 1199

Query: 1378 PPPARRHRHSIQLDLGDL 1395
            P    R   ++ LD   L
Sbjct: 1200 PRGVERTIRNLPLDHASL 1217



 Score = 33.1 bits (74), Expect = 2.0
 Identities = 40/156 (25%), Positives = 62/156 (39%), Gaps = 17/156 (10%)

Query: 320 PQPRPTRQGRPLPRQGATLAGRSSSNAPKYGRGQLNYPLPDFSKVGPRVRFPKDESYRPP 379
           P  R TR+  P    GA  A    + A ++     +Y  P+ S+       P D+ YRPP
Sbjct: 383 PPRRATREEPP----GAPFA---ENTAERFPPSYTSYLPPEPSR-------PTDQDYRPP 428

Query: 380 KSRSHNRKPQAPARPLIFKSPAEIVQEVLLSSGEAALAKDTPPAHPITR--VP-QEFQTP 436
            S +   +P  P        P+   +EV  S   A+ A+   PA   T   VP  +  + 
Sbjct: 429 ASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPFAQHSSL 488

Query: 437 EQATELVHQLQEDYHRLLTKYAEAENTIDQLRLGAK 472
           +   E++ + Q      L    E E     + LGA+
Sbjct: 489 DSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGAR 524



 Score = 32.0 bits (71), Expect = 4.4
 Identities = 47/177 (26%), Positives = 68/177 (38%), Gaps = 31/177 (17%)

Query: 662  TQQEPEPPGSDSALDSTPALPCLHQPTHLPAPSGQAPMPAIKTSCPEPATTTAAASTGPC 721
            T++E   PG++  L     L         PA  G   +PA++ S    AT T+  +  P 
Sbjct: 1240 TEEEEAEPGTEVDLAVLADLALT------PARRGLPALPAVEDS---EATETSDEAERPR 1290

Query: 722  PL--HVNVEVSSGNSEVEDRPQDPLARLRHKEL--QMEQVYHGLMERYLSVKSLPEA--- 774
            PL  H+ +E    N  +  +P  P   LR  E       ++    +  L    +  A   
Sbjct: 1291 PLLSHILLE---HNYALAVKPTPPAPALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAE 1347

Query: 775  ---------MRMEEEEEGEEE---EEEEGGGDSLEVDGVAATPGKAEATRVLPRQCP 819
                      R E EEEGEEE   EEEE    S   DG  A   ++  +    R+ P
Sbjct: 1348 EPKPQQLQQQREEGEEEGEEEGEEEEEESSDSSSSSDGEGALRRRSLRSHARRRRPP 1404


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 143/613 (23%), Positives = 191/613 (31%), Gaps = 99/613 (16%)

Query: 819  PVQAEKSHGAPLEEATEKMVSMKP--PGFQASLARDGHMSGLGKAEAAPPGPGVPPHPPG 876
            P      + AP+E  T +M    P  P     L   G    L      P G G      G
Sbjct: 187  PSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGG 246

Query: 877  TKSAASHQSSMT--SLEGSGISERLPQKPLHR--GGGPHLEETWMASPETDSGFVGSETS 932
                  H    T  S+  SG S   P KP     GGG       + S    + F     +
Sbjct: 247  PNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGN------LPSAPPPANFPHVTPN 300

Query: 933  RVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATEPS---TPRS 989
               P    P +  S  S  G  AQP    +P   A   +  G L P     P+   +P S
Sbjct: 301  LPPPPALRPLNNAS-ASPPGLGAQPLPGHLPSPHAM-GQGMGGLPPGPEKGPTLAPSPHS 358

Query: 990  QAQRYLSSPSGPLR---------QRAPNFSLERTLAAEMAVPGSEF----------EGHK 1030
                  S+P+ P+R           A + S   + ++    P S+               
Sbjct: 359  LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSL 418

Query: 1031 RISEQP-------LPNKTI---SPPPAPA-----------PAAAPLPCGPTETIPSFLLT 1069
             +S QP       LP++ +    PPP P            P   P   G   T    + T
Sbjct: 419  SVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVST 478

Query: 1070 RAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGS 1129
                 Q   + Q++  + + + +   H    G P  P  AF  P          P     
Sbjct: 479  HHHHHQQ--QQQQQQQQQQQQQQQQQHHGNSGPP--PPGAFPHPLEGGSSHHAHPYAMSP 534

Query: 1130 HYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKT 1189
              GS     L   P G   + PP  Q + S + P      S S+ S   S   +     +
Sbjct: 535  SLGS-----LRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPS 589

Query: 1190 TKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPI-- 1247
                PQ A           +P   T           + +  + P G  T S P   P   
Sbjct: 590  PSQGPQGA--------PYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGK 641

Query: 1248 RTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPS 1307
            R    G   T  P G  P      P   + G+PP   G    TS      T +  S T  
Sbjct: 642  RAPSPGAYKTATPPGYKPGS----PPSFRTGTPPGYRG----TSPPAGPGTFKPGSPTVG 693

Query: 1308 PKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQ 1367
            P          P PP G   L + PP PA PA     S   +   PA  Y  P  P    
Sbjct: 694  P---------GPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPV--- 741

Query: 1368 PAAKWPPTASPPP 1380
            P A+ P   SPPP
Sbjct: 742  PPARSP---SPPP 751



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 81/368 (22%), Positives = 116/368 (31%), Gaps = 65/368 (17%)

Query: 1068 LTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRP------A 1121
            + + GR + I E + E +    + +     P   SP+   S   R     G         
Sbjct: 67   VNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQ 126

Query: 1122 DSPATWGSHYGSKSTE----------RLPGEPRGEEQIVPPGRQRARSSSVPRE------ 1165
            D+ +T  S Y   S E          + P  P     + PP  Q     S PR+      
Sbjct: 127  DNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPP--DSTPRQPEASFE 184

Query: 1166 ----VLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKRGV------GSAGWPDRVTF 1215
                V      +  E P+  +F          PQ    G  GV      G  G     + 
Sbjct: 185  PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSV 244

Query: 1216 RGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDP-----------LGPP 1264
             G   G ++   +       +G    P  +P  T   GG +   P           L PP
Sbjct: 245  GGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPP 304

Query: 1265 PA------------DTLQCPLCGQVGSPPE-ADGPGSATSGAEKATTRRKASSTPSPKQR 1311
            PA                 PL G + SP     G G    G EK  T       PSP   
Sbjct: 305  PALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTL-----APSPHSL 359

Query: 1312 SKQAGSSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAK 1371
               + S+P PP    Y +++  + A  + +  SS    P+P  A    P+ P S  P   
Sbjct: 360  PPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFP--ASQALPSYPHSFPPPTS 417

Query: 1372 WPPTASPP 1379
               +  PP
Sbjct: 418  LSVSNQPP 425



 Score = 40.0 bits (92), Expect = 0.016
 Identities = 43/171 (25%), Positives = 65/171 (38%), Gaps = 12/171 (7%)

Query: 1231 AVPKGNGTVSCPHCRP---IRTQDAGGAVTGDPLGPP--PADTLQCPLCGQVGSPPEA-- 1283
            A P G G    P   P      Q  GG   G   GP   P+     P      +PP    
Sbjct: 315  ASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFP 374

Query: 1284 -DGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPP---APAPPA 1339
                 S+++ A  +++   +S++P P  ++  +     PPP    ++  PP    P+ P+
Sbjct: 375  YSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPS 434

Query: 1340 FAYISSVPIMPYPPAAVY-YAPAGPTSAQPAAKWPPTASPPPARRHRHSIQ 1389
             A  S  P  P P   +   + A P    P+     TA PP +  H H  Q
Sbjct: 435  QAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQ 485



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 114/485 (23%), Positives = 168/485 (34%), Gaps = 86/485 (17%)

Query: 863  AAPPGPGVPPHP-PGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPE 921
            + PP PG  PHP  G  S  +H  +M+   GS      P  P H    PH + ++  S  
Sbjct: 507  SGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGS--LRPYPPGPAHL-PPPHSQVSY--SQA 561

Query: 922  TDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRA 981
              +G   S +S  S  T    +  SH         P  +  P+ GA YP      +P   
Sbjct: 562  GPNGPPVSSSSNSSSSTSQGSYPCSH---------PSPSQGPQ-GAPYPFPP---VPTVT 608

Query: 982  TEPSTPRSQAQRYLSSPSG----------PLRQRAPNFSLERTLAAEMAVPGSEFE---- 1027
            T  +T  +      SSP+G          P  +RAP+    +T       PGS       
Sbjct: 609  TSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTG 668

Query: 1028 ---GHKRISEQPLPN--KTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQE 1082
               G++  S    P   K  SP   P P     P G     P      +G   +  ++++
Sbjct: 669  TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQ 728

Query: 1083 EVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLPGE 1142
            E +      E  +  P   SP+ P    D P+      A   A +  H            
Sbjct: 729  EPAEEYETPESPV--PPARSPSPPPKVVDVPSH-----ASQSARFNKHL----------- 770

Query: 1143 PRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKR 1202
             RG          R+    VP E  +L+    ++L          K  +++ Q AR+ K 
Sbjct: 771  DRGFNSCA-----RSDLYFVPLEGSKLA-KKRADL--------VEKVRREAEQRAREEKE 816

Query: 1203 GVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQ---DAGGAVTGD 1259
                    +R   R +    E    S K   +G   V CP   P+  +   + G AV   
Sbjct: 817  RERER---EREKEREREKERELE-RSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATV 872

Query: 1260 P--LGP--PPADTLQCPLCGQVGSPPEADGP-----GSATSGAEKATTRRKASSTPSPKQ 1310
            P  LGP  P   TL       V SP   + P     G+   G          SS P+ ++
Sbjct: 873  PPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALYSSDPAARE 932

Query: 1311 RSKQA 1315
            R ++A
Sbjct: 933  REREA 937



 Score = 35.8 bits (81), Expect = 0.31
 Identities = 38/153 (24%), Positives = 52/153 (33%), Gaps = 33/153 (21%)

Query: 1253 GGAVTGDPLGPP---PADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPK 1309
            GG ++G P+GP     A ++  P  G+   PP    P S +S         K  +TP   
Sbjct: 225  GGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTT--PISVSSSGASGAPPTKPPTTPVG- 281

Query: 1310 QRSKQAGSSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPA-------- 1361
                  G+ P  PP   +    P  P PPA   +++    P P       P         
Sbjct: 282  -----GGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP-PGLGAQPLPGHLPSPHAM 335

Query: 1362 -------------GPTSAQPAAKWPPTASPPPA 1381
                         GPT A      PP +S  PA
Sbjct: 336  GQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA 368


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 143/613 (23%), Positives = 191/613 (31%), Gaps = 99/613 (16%)

Query: 819  PVQAEKSHGAPLEEATEKMVSMKP--PGFQASLARDGHMSGLGKAEAAPPGPGVPPHPPG 876
            P      + AP+E  T +M    P  P     L   G    L      P G G      G
Sbjct: 187  PSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGG 246

Query: 877  TKSAASHQSSMT--SLEGSGISERLPQKPLHR--GGGPHLEETWMASPETDSGFVGSETS 932
                  H    T  S+  SG S   P KP     GGG       + S    + F     +
Sbjct: 247  PNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGN------LPSAPPPANFPHVTPN 300

Query: 933  RVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATEPS---TPRS 989
               P    P +  S  S  G  AQP    +P   A   +  G L P     P+   +P S
Sbjct: 301  LPPPPALRPLNNAS-ASPPGLGAQPLPGHLPSPHAM-GQGMGGLPPGPEKGPTLAPSPHS 358

Query: 990  QAQRYLSSPSGPLR---------QRAPNFSLERTLAAEMAVPGSEF----------EGHK 1030
                  S+P+ P+R           A + S   + ++    P S+               
Sbjct: 359  LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSL 418

Query: 1031 RISEQP-------LPNKTI---SPPPAPA-----------PAAAPLPCGPTETIPSFLLT 1069
             +S QP       LP++ +    PPP P            P   P   G   T    + T
Sbjct: 419  SVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVST 478

Query: 1070 RAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGS 1129
                 Q   + Q++  + + + +   H    G P  P  AF  P          P     
Sbjct: 479  HHHHHQQ--QQQQQQQQQQQQQQQQQHHGNSGPP--PPGAFPHPLEGGSSHHAHPYAMSP 534

Query: 1130 HYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKT 1189
              GS     L   P G   + PP  Q + S + P      S S+ S   S   +     +
Sbjct: 535  SLGS-----LRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPS 589

Query: 1190 TKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPI-- 1247
                PQ A           +P   T           + +  + P G  T S P   P   
Sbjct: 590  PSQGPQGA--------PYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGK 641

Query: 1248 RTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPS 1307
            R    G   T  P G  P      P   + G+PP   G    TS      T +  S T  
Sbjct: 642  RAPSPGAYKTATPPGYKPGS----PPSFRTGTPPGYRG----TSPPAGPGTFKPGSPTVG 693

Query: 1308 PKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQ 1367
            P          P PP G   L + PP PA PA     S   +   PA  Y  P  P    
Sbjct: 694  P---------GPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPV--- 741

Query: 1368 PAAKWPPTASPPP 1380
            P A+ P   SPPP
Sbjct: 742  PPARSP---SPPP 751



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 81/368 (22%), Positives = 116/368 (31%), Gaps = 65/368 (17%)

Query: 1068 LTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRP------A 1121
            + + GR + I E + E +    + +     P   SP+   S   R     G         
Sbjct: 67   VNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQ 126

Query: 1122 DSPATWGSHYGSKSTE----------RLPGEPRGEEQIVPPGRQRARSSSVPRE------ 1165
            D+ +T  S Y   S E          + P  P     + PP  Q     S PR+      
Sbjct: 127  DNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPP--DSTPRQPEASFE 184

Query: 1166 ----VLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKRGV------GSAGWPDRVTF 1215
                V      +  E P+  +F          PQ    G  GV      G  G     + 
Sbjct: 185  PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSV 244

Query: 1216 RGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDP-----------LGPP 1264
             G   G ++   +       +G    P  +P  T   GG +   P           L PP
Sbjct: 245  GGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPP 304

Query: 1265 PA------------DTLQCPLCGQVGSPPE-ADGPGSATSGAEKATTRRKASSTPSPKQR 1311
            PA                 PL G + SP     G G    G EK  T       PSP   
Sbjct: 305  PALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTL-----APSPHSL 359

Query: 1312 SKQAGSSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAK 1371
               + S+P PP    Y +++  + A  + +  SS    P+P  A    P+ P S  P   
Sbjct: 360  PPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFP--ASQALPSYPHSFPPPTS 417

Query: 1372 WPPTASPP 1379
               +  PP
Sbjct: 418  LSVSNQPP 425



 Score = 40.0 bits (92), Expect = 0.016
 Identities = 43/171 (25%), Positives = 65/171 (38%), Gaps = 12/171 (7%)

Query: 1231 AVPKGNGTVSCPHCRP---IRTQDAGGAVTGDPLGPP--PADTLQCPLCGQVGSPPEA-- 1283
            A P G G    P   P      Q  GG   G   GP   P+     P      +PP    
Sbjct: 315  ASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFP 374

Query: 1284 -DGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPP---APAPPA 1339
                 S+++ A  +++   +S++P P  ++  +     PPP    ++  PP    P+ P+
Sbjct: 375  YSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPS 434

Query: 1340 FAYISSVPIMPYPPAAVY-YAPAGPTSAQPAAKWPPTASPPPARRHRHSIQ 1389
             A  S  P  P P   +   + A P    P+     TA PP +  H H  Q
Sbjct: 435  QAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQ 485



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 114/485 (23%), Positives = 168/485 (34%), Gaps = 86/485 (17%)

Query: 863  AAPPGPGVPPHP-PGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPE 921
            + PP PG  PHP  G  S  +H  +M+   GS      P  P H    PH + ++  S  
Sbjct: 507  SGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGS--LRPYPPGPAHL-PPPHSQVSY--SQA 561

Query: 922  TDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRA 981
              +G   S +S  S  T    +  SH         P  +  P+ GA YP      +P   
Sbjct: 562  GPNGPPVSSSSNSSSSTSQGSYPCSH---------PSPSQGPQ-GAPYPFPP---VPTVT 608

Query: 982  TEPSTPRSQAQRYLSSPSG----------PLRQRAPNFSLERTLAAEMAVPGSEFE---- 1027
            T  +T  +      SSP+G          P  +RAP+    +T       PGS       
Sbjct: 609  TSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTG 668

Query: 1028 ---GHKRISEQPLPN--KTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQE 1082
               G++  S    P   K  SP   P P     P G     P      +G   +  ++++
Sbjct: 669  TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQ 728

Query: 1083 EVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLPGE 1142
            E +      E  +  P   SP+ P    D P+      A   A +  H            
Sbjct: 729  EPAEEYETPESPV--PPARSPSPPPKVVDVPSH-----ASQSARFNKHL----------- 770

Query: 1143 PRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKR 1202
             RG          R+    VP E  +L+    ++L          K  +++ Q AR+ K 
Sbjct: 771  DRGFNSCA-----RSDLYFVPLEGSKLA-KKRADL--------VEKVRREAEQRAREEKE 816

Query: 1203 GVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQ---DAGGAVTGD 1259
                    +R   R +    E    S K   +G   V CP   P+  +   + G AV   
Sbjct: 817  RERER---EREKEREREKERELE-RSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATV 872

Query: 1260 P--LGP--PPADTLQCPLCGQVGSPPEADGP-----GSATSGAEKATTRRKASSTPSPKQ 1310
            P  LGP  P   TL       V SP   + P     G+   G          SS P+ ++
Sbjct: 873  PPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALYSSDPAARE 932

Query: 1311 RSKQA 1315
            R ++A
Sbjct: 933  REREA 937



 Score = 35.8 bits (81), Expect = 0.31
 Identities = 38/153 (24%), Positives = 52/153 (33%), Gaps = 33/153 (21%)

Query: 1253 GGAVTGDPLGPP---PADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPK 1309
            GG ++G P+GP     A ++  P  G+   PP    P S +S         K  +TP   
Sbjct: 225  GGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTT--PISVSSSGASGAPPTKPPTTPVG- 281

Query: 1310 QRSKQAGSSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPA-------- 1361
                  G+ P  PP   +    P  P PPA   +++    P P       P         
Sbjct: 282  -----GGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP-PGLGAQPLPGHLPSPHAM 335

Query: 1362 -------------GPTSAQPAAKWPPTASPPPA 1381
                         GPT A      PP +S  PA
Sbjct: 336  GQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA 368


>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
          Length = 1312

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 169/732 (23%), Positives = 241/732 (32%), Gaps = 162/732 (22%)

Query: 666  PEPPGSDSALDSTPALPCLHQPTHLPAPSGQAPMPAIKTSCPEPATTTAAASTGPCPLHV 725
            P PP + S+  S+P+          P+PS  +P P      P P    A       P H 
Sbjct: 184  PAPPPAPSSASSSPS----------PSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHP 233

Query: 726  NVEVSSGNSEVEDRPQDPLARLRHKELQMEQVYHGLMERYLSVKSLPEAMRMEEEEEGEE 785
              E  S     E +  DP                   E   S  S        EEEE EE
Sbjct: 234  TDEAYSPPPAPEQK-YDPF------------------EPTGSNPSSSAGTPSPEEEEEEE 274

Query: 786  EEEEEGGGDSLEVDGVAATPGKAEATRVLPRQCPVQAEKSHGAPLEEATEKMVSMKPPGF 845
            EEEEE   D  E +G++ +                         +   +E +  +     
Sbjct: 275  EEEEEEEEDEEEEEGLSQS-------------------------ISRISETLAGIYDDN- 308

Query: 846  QASLARDGHMSGLGKAEAAP----PGPGVPPHPPGTKS--AASHQSSMTSLEGSGISERL 899
              SL++D       + +A P    P PG PP    T++  A   +  +   E     E  
Sbjct: 309  --SLSQDFPGDESPRPDAQPTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREGK 366

Query: 900  PQKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFA 959
                +   GG  L    +  P  DS     E   +    + P   LS     G  A+P  
Sbjct: 367  VSVEVVTAGGAALPPPLL--PPGDSEI---EEGEIVQPEEEPRLALSLFRPGGRAARPT- 420

Query: 960  ASVPRDGASYPKARGSLIPRRATEPSTPRS-QAQRYLSSPSGPLRQRAPNFSLERTLAAE 1018
                      P A  +   +   +P  PR+ +   +LS  +    + A    L     A 
Sbjct: 421  ----------PAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAP 470

Query: 1019 MAVPG--SEFEGHKRISEQPLPN---KTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGR 1073
             A        +  ++I  Q       ++ SP PAPAPAAA  P  PT         R+G 
Sbjct: 471  PAADSRWGGLDLRRKILTQRRERYRQRSPSPAPAPAPAAAAGP--PTRKKSRRERKRSG- 527

Query: 1074 DQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFD-RPARTRGRPADSPATWGSHYG 1132
                 E +E  S        S  QP   +P  PAS +D +  R+R R        GSH  
Sbjct: 528  -----EAKEAAS------SSSGTQP---APPAPASPWDSKKHRSRDRKP------GSHAS 567

Query: 1133 SKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKD 1192
            S +  R     R         R+R+RS+   R   R S S E         S    T+  
Sbjct: 568  SSARRRSRSRSRSRST-----RRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSS 622

Query: 1193 SPQAARDGKRGV-----GSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSC------ 1241
            S  + R+  RG      GS     R   RG+    +    +P   P  +G+ SC      
Sbjct: 623  S-SSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSR 681

Query: 1242 ------PHCRPI---------RTQDAGGAVTGDPLGPPPADTLQCP---------LCGQV 1277
                  P  + +         RT   G     DP GP PA               L G+ 
Sbjct: 682  RRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEE 741

Query: 1278 --GSPPEAD----GPGSATSGAEKATTRRKA-----SSTPSPKQRSKQAGSSPRPPPGLW 1326
              G   + D    G  S++S + +  +RRKA           + R +   S    PP   
Sbjct: 742  RGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKES 801

Query: 1327 YLATAPPAPAPP 1338
              ++ PP P PP
Sbjct: 802  APSSGPP-PKPP 812



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 51/203 (25%), Positives = 73/203 (35%), Gaps = 14/203 (6%)

Query: 860  KAEAAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMAS 919
            K  + PP    PP P  T  + +  SS  + E S + E   ++   RGG    EE     
Sbjct: 972  KVPSTPPPKAAPPPPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEEEEEEEEEE 1031

Query: 920  PETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASY--PKARGSLI 977
             E +      E     P T T     +  + A     P A S   D  +   P +R S +
Sbjct: 1032 EEEE------EEEEQQPATTTA----TSTAAAAPSTAPSAGSTAGDSGAEDGPASRVSQL 1081

Query: 978  PRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPL 1037
            P     P  P +       + SG L   A  F +E    A  A      +   +I     
Sbjct: 1082 P--TLPPPMPWNLPAGVDCTTSGVLALTALLFKMEEANLASRAKAQELIQATNQILSHRK 1139

Query: 1038 PNKTISPPPAPAPAAAPLPCGPT 1060
            P  ++   PAP P +  LP GP+
Sbjct: 1140 PPSSLGMTPAPVPTSLGLPPGPS 1162



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 36/126 (28%), Positives = 49/126 (38%), Gaps = 15/126 (11%)

Query: 1287 GSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAF-----A 1341
            G+   G         ASS+PSP   S      P PPP       APPAP  P F      
Sbjct: 178  GTGDGGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPP------PAPPAPPAPRFDIYDPF 231

Query: 1342 YISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPPPARRHRHSIQLDLGDLEE---L 1398
            + +     P P     Y P  PT + P++    T SP          + +  D EE   L
Sbjct: 232  HPTDEAYSPPPAPEQKYDPFEPTGSNPSSS-AGTPSPEEEEEEEEEEEEEEEDEEEEEGL 290

Query: 1399 NKALSR 1404
            ++++SR
Sbjct: 291  SQSISR 296



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 70/313 (22%), Positives = 110/313 (35%), Gaps = 55/313 (17%)

Query: 866  PGPGVPPHPP-----GTKSAASH--------QSSMTSLEGSGISERLPQKPLHRGGGPHL 912
            P  G PP PP     G+ S++S         QS +  L   G+S   P K     G    
Sbjct: 803  PSSGPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAG---- 858

Query: 913  EETWMASPETDSGFVGSETSR----VSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGAS 968
                        G +G + SR     SP  +  E   + ++ A   +     +  +  A 
Sbjct: 859  -----------LGSIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAG 907

Query: 969  YPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSE--- 1025
              K +G+   +  T+PS  R +  R      G   Q +   S   + +      G+E   
Sbjct: 908  AKKTKGT---KGKTKPSKTRKKV-RSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEETS 963

Query: 1026 FEGHKRISEQPL--PNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAIC----E 1079
            + G +R ++ P   P K   PPPA  P +  +         SFL   A  +  +     E
Sbjct: 964  WSGEERAAKVPSTPPPKAAPPPPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEE 1023

Query: 1080 LQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERL 1139
             +EE        E+   QP   + T  A+A          P+ +P+  GS  G    E  
Sbjct: 1024 EEEEEEEEEEEEEEEEQQPATTTATSTAAA---------APSTAPSA-GSTAGDSGAEDG 1073

Query: 1140 PGEPRGEEQIVPP 1152
            P     +   +PP
Sbjct: 1074 PASRVSQLPTLPP 1086


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 104/443 (23%), Positives = 159/443 (35%), Gaps = 85/443 (19%)

Query: 981  ATEPSTPRSQ--AQRYLSSPSG----PLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISE 1034
            A++  T + Q   Q+    P G    PL+Q+ P             +P  +  G   + +
Sbjct: 184  ASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPK-----------PIPKQQGPGRDPLQQ 232

Query: 1035 QPLPNKTISPPPA-----PAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQEEVSRLRL 1089
               P    S  P      P     P+  GPT+T  +        D A   LQ + SR + 
Sbjct: 233  DGTPKSISSQQPEKIKSQPPGTGKPIQ-GPTQTPQT--------DHAKLPLQRDASRPQT 283

Query: 1090 RLEDSLH----QPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLPGEPRG 1145
            +  D +     +P   SP++P      P +    PA  P   G         + P +P G
Sbjct: 284  KQADIVRGESVKPSLPSPSKPPIQQPTPGKP---PAQQP---GHEKSQPGPAKPPAQPSG 337

Query: 1146 -------EEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAAR 1198
                   +   V P  Q   ++  P + L       ++ P+    SEK  + +  P+A  
Sbjct: 338  LTKPLAQQPGTVKPPVQPPGTTKPPAQPL-----GPAKPPAQQTGSEKPSSEQPGPKALA 392

Query: 1199 D----GKRGV---GSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGT-VSCPHCRPIRTQ 1250
                 GK      G A  P +     +    +  + SP   P    T V  P    I  Q
Sbjct: 393  QPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452

Query: 1251 DAG-GAVTGDPLGP--PPADTLQCPLCGQVGSPPEADGP--------GSATSGAEKATTR 1299
             AG G  +    GP  PP+      L G    PP+  GP        GSA   +++  + 
Sbjct: 453  QAGPGKTSAQQTGPTKPPSQ-----LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST 507

Query: 1300 RKASSTPSPKQRSKQAGSSPRPP---PGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAV 1356
            +     P P + S Q   S +PP   PG    +   P+PA P+ A  S+ P+        
Sbjct: 508  KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS-AQQSTKPVSQTGSG-- 564

Query: 1357 YYAPAGPTSAQPAAKWPPTASPP 1379
               P  P +  P+AK PP+   P
Sbjct: 565  --KPLQPPTVSPSAKQPPSQGLP 585



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 121/544 (22%), Positives = 185/544 (34%), Gaps = 90/544 (16%)

Query: 889  SLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSPLTQTPEHRLSHI 948
            SLEG G+ E L       GG      +   SP   +   G E      L+Q  E     I
Sbjct: 6    SLEGEGLPEGLAAAAAAGGGA-----SGAGSPSHTAIPAGMEAD----LSQLSEEERRQI 56

Query: 949  STAGTLAQPFA-ASVPRDGASYPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAP 1007
            +   + AQ     SVP   A  P    S+  ++  + S P  Q+ R    P  P R   P
Sbjct: 57   AAVMSRAQGLPKGSVPPAAAESP----SMHRKQELDSSHPPKQSGR----PPDPGRPAQP 108

Query: 1008 NFSLERT---LAAEMAVPGSE-----FEGHKRISEQPLPNKTISPPP--APAPAAAPLPC 1057
              S  RT     +E  +PG        +  K  ++    +K+   P   +   A + +  
Sbjct: 109  GLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSS 168

Query: 1058 GPTETIPSFLLTRAGRDQA-ICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPART 1116
               +  P  L++ +   Q    + Q+ V + + + E  +  PLQ  P +P      P R 
Sbjct: 169  VVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRD 228

Query: 1117 RGRPADSPATWGSHYGSKSTERLPGE----------PRGEEQIVPPGRQRARSSSVPREV 1166
              +   +P +  S    K   + PG           P+ +   +P  R  +R  +   ++
Sbjct: 229  PLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADI 288

Query: 1167 LRLSLSSESELPSLPLFSEK--SKTTKDSPQAARDG--KRGVGSAGWPDRVTFRGQYTGH 1222
            +R     ES  PSLP  S+    + T   P A + G  K   G A  P + +   +    
Sbjct: 289  VR----GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQ 344

Query: 1223 EYHVLSPKAVPKGNGTVSCPHCRPIR--TQDAG--------------------GAVTGDP 1260
            +   + P   P G          P +   Q  G                    G      
Sbjct: 345  QPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQ 404

Query: 1261 LGPPPADTLQC----PLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAG 1316
             GP    T Q     PL  Q G    A  PG   +  ++    +  +    P + S Q  
Sbjct: 405  PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQT 464

Query: 1317 SSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTA 1376
               +PP  L   A  PP    PA            PP      P  P SA+P ++ P + 
Sbjct: 465  GPTKPPSQLPGPAKPPPQQPGPA-----------KPP------PQQPGSAKPPSQQPGST 507

Query: 1377 SPPP 1380
             PPP
Sbjct: 508  KPPP 511



 Score = 50.8 bits (120), Expect = 9e-06
 Identities = 163/831 (19%), Positives = 281/831 (33%), Gaps = 169/831 (20%)

Query: 626  AGSKGTPGRFDPRRELEAEIYRLGSCLEELKEHIDQTQQEPEPPGSDSALDSTPALPCLH 685
            A   G+P        +EA++ +L    EE +  I       +     S   +    P +H
Sbjct: 26   ASGAGSPSHTAIPAGMEADLSQLS---EEERRQIAAVMSRAQGLPKGSVPPAAAESPSMH 82

Query: 686  QP-----THLPAPSGQAPMPA--IKTSCPEPATTTAAAST----GPCPLHVNVEVSSGNS 734
            +      +H P  SG+ P P    +    +  TT    S     G  P  ++++ S   +
Sbjct: 83   RKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRT 142

Query: 735  EVEDRPQDPLARLRHKELQMEQVYHGLMERYLSVKSLPEAMRMEEEEEGEEEEEEEGGGD 794
            ++++  +  +      E+        ++ ++     + ++   +EE   +++  ++  G 
Sbjct: 143  DLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQG- 201

Query: 795  SLEVDGVAATPGKAEATRVLPRQCPVQAEKSHGAPLEE-ATEKMVSMKPPGFQASLARDG 853
              + +G+   P + +  + +P+Q     +     PL++  T K +S + P          
Sbjct: 202  --KPEGIIKPPLQQQPPKPIPKQ-----QGPGRDPLQQDGTPKSISSQQPE--------- 245

Query: 854  HMSGLGKAEAAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLE 913
                  K ++ PPG G P   P       H  +   L+      +  Q  + RG      
Sbjct: 246  ------KIKSQPPGTGKPIQGPTQTPQTDH--AKLPLQRDASRPQTKQADIVRG------ 291

Query: 914  ETWMASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKAR 973
            E+   S  + S     + +   P  Q P H  S    A   AQP   + P   A  P   
Sbjct: 292  ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPL--AQQP--- 346

Query: 974  GSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRIS 1033
            G++ P     P T +  AQ     P GP +  A     E+        P SE  G K ++
Sbjct: 347  GTVKPP-VQPPGTTKPPAQ-----PLGPAKPPAQQTGSEK--------PSSEQPGPKALA 392

Query: 1034 EQPLPNKTISPPPAPA---------------------PAAAPLPCGPTET---------I 1063
            + P   KT +  P PA                     PA AP   GPT+T         I
Sbjct: 393  QPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP---GPTKTPVQQPGPGKI 449

Query: 1064 PSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGR---P 1120
            P+    +AG  +   +                    Q  PT+P S    PA+   +   P
Sbjct: 450  PA---QQAGPGKTSAQ--------------------QTGPTKPPSQLPGPAKPPPQQPGP 486

Query: 1121 ADSPATWGSHYGSKSTERLPGEPRGEEQIVPPGR---QRARSSSVP-REVLRLSLSSESE 1176
            A  P        +K   + PG  +   Q   P +   Q+  S+  P ++      S++  
Sbjct: 487  AKPPPQQPG--SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP 544

Query: 1177 LPSLPLFSEKSKTTKDS-------PQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSP 1229
             P+ P   + +K    +       P       +   S G P  +      T    HV   
Sbjct: 545  SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHV--- 601

Query: 1230 KAVPKGNGTVSCPHCRPIRTQDAGGAVTGDPLGPPPADT-------LQCPLCGQVGSP-- 1280
               P+     +C  C+       G         P P  T       L C +   +G    
Sbjct: 602  ---PEKANFNTCTECQTTVCSLCG-------FNPNPHLTEVKEWLCLNCQMKRALGGDLA 651

Query: 1281 PEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAF 1340
            P    P      A   TT   + S+P P+Q S +  ++P+       L+ AP    PP  
Sbjct: 652  PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD-----LSKAPEPKKPPPL 706

Query: 1341 AYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPPPARRHRHSIQLD 1391
              +    +   P A     P   + ++PA   PP     P+ + +  +  D
Sbjct: 707  --VKQPTLHGSPSAKAKQPPEADSLSKPA---PPKEPSVPSEQDKAPVADD 752



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 124/598 (20%), Positives = 195/598 (32%), Gaps = 128/598 (21%)

Query: 662  TQQEPEPPGSDSALDSTPALPCLHQPTHLPAPSGQAPMPAIKTSCPEPATTTAAASTGPC 721
            T+  P+ PG        PA P   QP     PS Q          P PA  +A  ST P 
Sbjct: 507  TKPPPQQPG--------PAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV 558

Query: 722  ----------PLHVNVEVSSGNSEVEDRPQDPLARLRHKELQMEQV--YHGLMERYLSVK 769
                      P  V+       S+   +   PL       L + +   ++   E   +V 
Sbjct: 559  SQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVC 618

Query: 770  SL------PEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATPGKAE---ATRVLPRQCPV 820
            SL      P    ++E      + +   GGD   V        K      T  + +  P 
Sbjct: 619  SLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQ 678

Query: 821  QAE---KSHGAPLEEATEKMVSMKPPGF--QASLARDGHMSGLGKAEAAPPGPGVP-PHP 874
              +   K   AP ++ ++     KPP    Q +L    H S   KA+  P    +  P P
Sbjct: 679  PQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL----HGSPSAKAKQPPEADSLSKPAP 734

Query: 875  PGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSETSRV 934
            P   S  S Q        + +++  P++P             M  P TD   V S ++  
Sbjct: 735  PKEPSVPSEQDK------APVADDKPKQPK------------MVKPTTD--LVSSSSATT 774

Query: 935  SPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATEPSTPRSQAQRY 994
             P    P  ++   +   T   P      +   S+P     + P  +     P S + + 
Sbjct: 775  KP--DIPSSKVQSQAEEKT-TPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDS-KI 830

Query: 995  LSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRIS-----EQPLPNKT-ISPPP-- 1046
            +S P                       P SE +G K++      E+P   +T +SP P  
Sbjct: 831  ISHPG----------------------PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868

Query: 1047 APAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRP 1106
             P P  +P P GP  T    + T     Q   + QE+  R  L L      P +  PT P
Sbjct: 869  KPMPKGSPTPPGPRPTAGQTVPT----PQQSPKPQEQSRRFSLNLGSITDAP-KSQPTTP 923

Query: 1107 ------------ASAFDRPAR---TRGRPADSPATWGSHYGSKSTERLPGEPRGEEQIVP 1151
                        AS F + +    T G+P       G H  S     +   P   +    
Sbjct: 924  QETVTGKLFGFGASIFSQASNLISTAGQP-------GPHSQSGPGAPMKQAPAPSQPPTS 976

Query: 1152 PGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSK--------TTKDSPQAARDGK 1201
             G  ++   + P     + +  E++ P+      K++         T+  P   +D K
Sbjct: 977  QGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSK 1034



 Score = 31.6 bits (70), Expect = 5.8
 Identities = 33/125 (26%), Positives = 42/125 (33%), Gaps = 40/125 (32%)

Query: 1264 PPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASST--------PSPKQRSKQA 1315
            PP+  +  P+  Q+ +     G    T G EK  ++  + S         P P  RS   
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGE---TFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSL 2399

Query: 1316 GSSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPT 1375
              S +PPP        PP P PP        P  P PP              P    PP 
Sbjct: 2400 DISAQPPP--------PPPPPPPP-------PPPPPPP--------------PPPPLPPP 2430

Query: 1376 ASPPP 1380
             SP P
Sbjct: 2431 TSPKP 2435



 Score = 31.2 bits (69), Expect = 7.5
 Identities = 39/143 (27%), Positives = 53/143 (37%), Gaps = 28/143 (19%)

Query: 301 KTSPKPLPSRFIGSISPLNPQPRPTRQGRPLPRQGATLAGRSSSNAPKYGRGQLNYPLPD 360
           +T P   PS+  G   P   QP P    +P P+Q        S+  P    G      P 
Sbjct: 463 QTGPTKPPSQLPGPAKPPPQQPGP---AKPPPQQ------PGSAKPPSQQPGSTK---PP 510

Query: 361 FSKVGPRVRFPKDE-SYRPPKSRSHNRKPQA----PARPLIFKSPAEIVQEVLLSSGEAA 415
             + GP    P+   S +PP  +  + KP A    PA+P   +S   + Q     SG+  
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ---TGSGK-- 565

Query: 416 LAKDTPPAHPITRVPQEFQTPEQ 438
                 P  P T  P   Q P Q
Sbjct: 566 ------PLQPPTVSPSAKQPPSQ 582


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 104/443 (23%), Positives = 159/443 (35%), Gaps = 85/443 (19%)

Query: 981  ATEPSTPRSQ--AQRYLSSPSG----PLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISE 1034
            A++  T + Q   Q+    P G    PL+Q+ P             +P  +  G   + +
Sbjct: 184  ASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPK-----------PIPKQQGPGRDPLQQ 232

Query: 1035 QPLPNKTISPPPA-----PAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQEEVSRLRL 1089
               P    S  P      P     P+  GPT+T  +        D A   LQ + SR + 
Sbjct: 233  DGTPKSISSQQPEKIKSQPPGTGKPIQ-GPTQTPQT--------DHAKLPLQRDASRPQT 283

Query: 1090 RLEDSLH----QPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLPGEPRG 1145
            +  D +     +P   SP++P      P +    PA  P   G         + P +P G
Sbjct: 284  KQADIVRGESVKPSLPSPSKPPIQQPTPGKP---PAQQP---GHEKSQPGPAKPPAQPSG 337

Query: 1146 -------EEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAAR 1198
                   +   V P  Q   ++  P + L       ++ P+    SEK  + +  P+A  
Sbjct: 338  LTKPLAQQPGTVKPPVQPPGTTKPPAQPL-----GPAKPPAQQTGSEKPSSEQPGPKALA 392

Query: 1199 D----GKRGV---GSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGT-VSCPHCRPIRTQ 1250
                 GK      G A  P +     +    +  + SP   P    T V  P    I  Q
Sbjct: 393  QPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452

Query: 1251 DAG-GAVTGDPLGP--PPADTLQCPLCGQVGSPPEADGP--------GSATSGAEKATTR 1299
             AG G  +    GP  PP+      L G    PP+  GP        GSA   +++  + 
Sbjct: 453  QAGPGKTSAQQTGPTKPPSQ-----LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST 507

Query: 1300 RKASSTPSPKQRSKQAGSSPRPP---PGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAV 1356
            +     P P + S Q   S +PP   PG    +   P+PA P+ A  S+ P+        
Sbjct: 508  KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS-AQQSTKPVSQTGSG-- 564

Query: 1357 YYAPAGPTSAQPAAKWPPTASPP 1379
               P  P +  P+AK PP+   P
Sbjct: 565  --KPLQPPTVSPSAKQPPSQGLP 585



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 121/544 (22%), Positives = 185/544 (34%), Gaps = 90/544 (16%)

Query: 889  SLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSPLTQTPEHRLSHI 948
            SLEG G+ E L       GG      +   SP   +   G E      L+Q  E     I
Sbjct: 6    SLEGEGLPEGLAAAAAAGGGA-----SGAGSPSHTAIPAGMEAD----LSQLSEEERRQI 56

Query: 949  STAGTLAQPFA-ASVPRDGASYPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAP 1007
            +   + AQ     SVP   A  P    S+  ++  + S P  Q+ R    P  P R   P
Sbjct: 57   AAVMSRAQGLPKGSVPPAAAESP----SMHRKQELDSSHPPKQSGR----PPDPGRPAQP 108

Query: 1008 NFSLERT---LAAEMAVPGSE-----FEGHKRISEQPLPNKTISPPP--APAPAAAPLPC 1057
              S  RT     +E  +PG        +  K  ++    +K+   P   +   A + +  
Sbjct: 109  GLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSS 168

Query: 1058 GPTETIPSFLLTRAGRDQA-ICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPART 1116
               +  P  L++ +   Q    + Q+ V + + + E  +  PLQ  P +P      P R 
Sbjct: 169  VVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRD 228

Query: 1117 RGRPADSPATWGSHYGSKSTERLPGE----------PRGEEQIVPPGRQRARSSSVPREV 1166
              +   +P +  S    K   + PG           P+ +   +P  R  +R  +   ++
Sbjct: 229  PLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADI 288

Query: 1167 LRLSLSSESELPSLPLFSEK--SKTTKDSPQAARDG--KRGVGSAGWPDRVTFRGQYTGH 1222
            +R     ES  PSLP  S+    + T   P A + G  K   G A  P + +   +    
Sbjct: 289  VR----GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQ 344

Query: 1223 EYHVLSPKAVPKGNGTVSCPHCRPIR--TQDAG--------------------GAVTGDP 1260
            +   + P   P G          P +   Q  G                    G      
Sbjct: 345  QPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQ 404

Query: 1261 LGPPPADTLQC----PLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAG 1316
             GP    T Q     PL  Q G    A  PG   +  ++    +  +    P + S Q  
Sbjct: 405  PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQT 464

Query: 1317 SSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTA 1376
               +PP  L   A  PP    PA            PP      P  P SA+P ++ P + 
Sbjct: 465  GPTKPPSQLPGPAKPPPQQPGPA-----------KPP------PQQPGSAKPPSQQPGST 507

Query: 1377 SPPP 1380
             PPP
Sbjct: 508  KPPP 511



 Score = 50.8 bits (120), Expect = 9e-06
 Identities = 163/831 (19%), Positives = 281/831 (33%), Gaps = 169/831 (20%)

Query: 626  AGSKGTPGRFDPRRELEAEIYRLGSCLEELKEHIDQTQQEPEPPGSDSALDSTPALPCLH 685
            A   G+P        +EA++ +L    EE +  I       +     S   +    P +H
Sbjct: 26   ASGAGSPSHTAIPAGMEADLSQLS---EEERRQIAAVMSRAQGLPKGSVPPAAAESPSMH 82

Query: 686  QP-----THLPAPSGQAPMPA--IKTSCPEPATTTAAAST----GPCPLHVNVEVSSGNS 734
            +      +H P  SG+ P P    +    +  TT    S     G  P  ++++ S   +
Sbjct: 83   RKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRT 142

Query: 735  EVEDRPQDPLARLRHKELQMEQVYHGLMERYLSVKSLPEAMRMEEEEEGEEEEEEEGGGD 794
            ++++  +  +      E+        ++ ++     + ++   +EE   +++  ++  G 
Sbjct: 143  DLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQG- 201

Query: 795  SLEVDGVAATPGKAEATRVLPRQCPVQAEKSHGAPLEE-ATEKMVSMKPPGFQASLARDG 853
              + +G+   P + +  + +P+Q     +     PL++  T K +S + P          
Sbjct: 202  --KPEGIIKPPLQQQPPKPIPKQ-----QGPGRDPLQQDGTPKSISSQQPE--------- 245

Query: 854  HMSGLGKAEAAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLE 913
                  K ++ PPG G P   P       H  +   L+      +  Q  + RG      
Sbjct: 246  ------KIKSQPPGTGKPIQGPTQTPQTDH--AKLPLQRDASRPQTKQADIVRG------ 291

Query: 914  ETWMASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKAR 973
            E+   S  + S     + +   P  Q P H  S    A   AQP   + P   A  P   
Sbjct: 292  ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPL--AQQP--- 346

Query: 974  GSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRIS 1033
            G++ P     P T +  AQ     P GP +  A     E+        P SE  G K ++
Sbjct: 347  GTVKPP-VQPPGTTKPPAQ-----PLGPAKPPAQQTGSEK--------PSSEQPGPKALA 392

Query: 1034 EQPLPNKTISPPPAPA---------------------PAAAPLPCGPTET---------I 1063
            + P   KT +  P PA                     PA AP   GPT+T         I
Sbjct: 393  QPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP---GPTKTPVQQPGPGKI 449

Query: 1064 PSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGR---P 1120
            P+    +AG  +   +                    Q  PT+P S    PA+   +   P
Sbjct: 450  PA---QQAGPGKTSAQ--------------------QTGPTKPPSQLPGPAKPPPQQPGP 486

Query: 1121 ADSPATWGSHYGSKSTERLPGEPRGEEQIVPPGR---QRARSSSVP-REVLRLSLSSESE 1176
            A  P        +K   + PG  +   Q   P +   Q+  S+  P ++      S++  
Sbjct: 487  AKPPPQQPG--SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP 544

Query: 1177 LPSLPLFSEKSKTTKDS-------PQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSP 1229
             P+ P   + +K    +       P       +   S G P  +      T    HV   
Sbjct: 545  SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHV--- 601

Query: 1230 KAVPKGNGTVSCPHCRPIRTQDAGGAVTGDPLGPPPADT-------LQCPLCGQVGSP-- 1280
               P+     +C  C+       G         P P  T       L C +   +G    
Sbjct: 602  ---PEKANFNTCTECQTTVCSLCG-------FNPNPHLTEVKEWLCLNCQMKRALGGDLA 651

Query: 1281 PEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAF 1340
            P    P      A   TT   + S+P P+Q S +  ++P+       L+ AP    PP  
Sbjct: 652  PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD-----LSKAPEPKKPPPL 706

Query: 1341 AYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPPPARRHRHSIQLD 1391
              +    +   P A     P   + ++PA   PP     P+ + +  +  D
Sbjct: 707  --VKQPTLHGSPSAKAKQPPEADSLSKPA---PPKEPSVPSEQDKAPVADD 752



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 124/598 (20%), Positives = 195/598 (32%), Gaps = 128/598 (21%)

Query: 662  TQQEPEPPGSDSALDSTPALPCLHQPTHLPAPSGQAPMPAIKTSCPEPATTTAAASTGPC 721
            T+  P+ PG        PA P   QP     PS Q          P PA  +A  ST P 
Sbjct: 507  TKPPPQQPG--------PAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV 558

Query: 722  ----------PLHVNVEVSSGNSEVEDRPQDPLARLRHKELQMEQV--YHGLMERYLSVK 769
                      P  V+       S+   +   PL       L + +   ++   E   +V 
Sbjct: 559  SQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVC 618

Query: 770  SL------PEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATPGKAE---ATRVLPRQCPV 820
            SL      P    ++E      + +   GGD   V        K      T  + +  P 
Sbjct: 619  SLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQ 678

Query: 821  QAE---KSHGAPLEEATEKMVSMKPPGF--QASLARDGHMSGLGKAEAAPPGPGVP-PHP 874
              +   K   AP ++ ++     KPP    Q +L    H S   KA+  P    +  P P
Sbjct: 679  PQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL----HGSPSAKAKQPPEADSLSKPAP 734

Query: 875  PGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSETSRV 934
            P   S  S Q        + +++  P++P             M  P TD   V S ++  
Sbjct: 735  PKEPSVPSEQDK------APVADDKPKQPK------------MVKPTTD--LVSSSSATT 774

Query: 935  SPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATEPSTPRSQAQRY 994
             P    P  ++   +   T   P      +   S+P     + P  +     P S + + 
Sbjct: 775  KP--DIPSSKVQSQAEEKT-TPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDS-KI 830

Query: 995  LSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRIS-----EQPLPNKT-ISPPP-- 1046
            +S P                       P SE +G K++      E+P   +T +SP P  
Sbjct: 831  ISHPG----------------------PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868

Query: 1047 APAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRP 1106
             P P  +P P GP  T    + T     Q   + QE+  R  L L      P +  PT P
Sbjct: 869  KPMPKGSPTPPGPRPTAGQTVPT----PQQSPKPQEQSRRFSLNLGSITDAP-KSQPTTP 923

Query: 1107 ------------ASAFDRPAR---TRGRPADSPATWGSHYGSKSTERLPGEPRGEEQIVP 1151
                        AS F + +    T G+P       G H  S     +   P   +    
Sbjct: 924  QETVTGKLFGFGASIFSQASNLISTAGQP-------GPHSQSGPGAPMKQAPAPSQPPTS 976

Query: 1152 PGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSK--------TTKDSPQAARDGK 1201
             G  ++   + P     + +  E++ P+      K++         T+  P   +D K
Sbjct: 977  QGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSK 1034



 Score = 31.6 bits (70), Expect = 5.8
 Identities = 33/125 (26%), Positives = 42/125 (33%), Gaps = 40/125 (32%)

Query: 1264 PPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASST--------PSPKQRSKQA 1315
            PP+  +  P+  Q+ +     G    T G EK  ++  + S         P P  RS   
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGE---TFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSL 2399

Query: 1316 GSSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPT 1375
              S +PPP        PP P PP        P  P PP              P    PP 
Sbjct: 2400 DISAQPPP--------PPPPPPPP-------PPPPPPP--------------PPPPLPPP 2430

Query: 1376 ASPPP 1380
             SP P
Sbjct: 2431 TSPKP 2435



 Score = 31.2 bits (69), Expect = 7.5
 Identities = 39/143 (27%), Positives = 53/143 (37%), Gaps = 28/143 (19%)

Query: 301 KTSPKPLPSRFIGSISPLNPQPRPTRQGRPLPRQGATLAGRSSSNAPKYGRGQLNYPLPD 360
           +T P   PS+  G   P   QP P    +P P+Q        S+  P    G      P 
Sbjct: 463 QTGPTKPPSQLPGPAKPPPQQPGP---AKPPPQQ------PGSAKPPSQQPGSTK---PP 510

Query: 361 FSKVGPRVRFPKDE-SYRPPKSRSHNRKPQA----PARPLIFKSPAEIVQEVLLSSGEAA 415
             + GP    P+   S +PP  +  + KP A    PA+P   +S   + Q     SG+  
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ---TGSGK-- 565

Query: 416 LAKDTPPAHPITRVPQEFQTPEQ 438
                 P  P T  P   Q P Q
Sbjct: 566 ------PLQPPTVSPSAKQPPSQ 582


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 127/533 (23%), Positives = 181/533 (33%), Gaps = 96/533 (18%)

Query: 967  ASYPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEF 1026
            +S  K   S  PRR       RS + R  SSP    R+R+ + S      +    P  E 
Sbjct: 161  SSREKRERSRSPRRRKS----RSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEK 216

Query: 1027 EGHKRISEQPLPNKTISPP--------------PAPAPAAAPLPCGPTETIPSFLLTRAG 1072
            +  ++  E P P+  +  P              P P P   P    P +           
Sbjct: 217  K--EKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT 274

Query: 1073 RDQAICELQEEVSRLRLRLEDSLH---------QPLQGSPTRPASAFDRPARTRGRPADS 1123
            R ++        SR R R     H         +    SP R  S   RP+  R  P   
Sbjct: 275  RPRS---RSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRR 331

Query: 1124 PATWGSHYGSKSTER--------LPGEPRGEEQI---VPPGRQRARSSSVPREVLRLSLS 1172
                  H  S+S  R        L G            PP +   R+SS PR+  RLS S
Sbjct: 332  MPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPS 391

Query: 1173 SES----ELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVL- 1227
            +        PS P           +PQ +   ++   S   P R +  G+ T H+     
Sbjct: 392  ASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVS-PGRTS--GKVTKHKGTEKR 448

Query: 1228 -SPKAVPKGN----------------GTVSCPHCRPIRTQ------DAGGAVTGDPLGPP 1264
             SP   PK                     S    R  R Q      D+G + + +   P 
Sbjct: 449  ESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPK 508

Query: 1265 PADTLQCPLCGQVG-----SPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSP 1319
             +        G+VG     SP  +  P S     ++ + R +   +PSP    ++   SP
Sbjct: 509  RSHVKN----GEVGRRRRHSPSRSASP-SPRKRQKETSPRGRRRRSPSPPPTRRRRSPSP 563

Query: 1320 RPPPGLWYLATAPP---APAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPP-- 1374
             PPP      T PP    P+PP     S  P    PP    Y+P+ P   + A+  PP  
Sbjct: 564  APPPRRRRTPTPPPRRRTPSPPP-RRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPK 622

Query: 1375 ---TASPPPARRHRHS---IQLDLGDLEELNKALSRAVQAAESVRSTTRQMRS 1421
               + SPPP RR  HS    Q      +  + +LS   +   S   +TR+ RS
Sbjct: 623  RRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARS 675



 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 61/275 (22%), Positives = 101/275 (36%), Gaps = 27/275 (9%)

Query: 191 PSVELSPARSWSSGTVSLDHPSDSLDSTWEGETDGPQPTALAETLPEGPSHHLLSPDGRT 250
           P    SP     S ++S  H   S  S    E   PQP             H  SP  R 
Sbjct: 641 PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPN----------KRHSPSPRPRA 690

Query: 251 GGSVARATPMEFQDSSAPPA-QSPQHATDRWRRETTRFFCPQPKEHIWKQTKTSPKPLPS 309
             + +   P+    SS+P   QSP  +T   RR +     P+PK+    +   SP P   
Sbjct: 691 PQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRT---PEPKKI---KKAASPSPQSV 744

Query: 310 RFIGSISPLNPQPRPTRQGRPLPRQGATLAGRSSSNAPKYGRGQLNYPLP--------DF 361
           R + S   ++  P P  +  P P         S++ +P     +   P P        D 
Sbjct: 745 RRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQ 804

Query: 362 SKVGPRVRFPKDESYRPPKSRSHNRKPQAPARPLIFKSPAEIVQEVLLSSGEAALAKDTP 421
              G + +  KD+ ++  K + H +  +      +  + A  V    +++    LA++ P
Sbjct: 805 EGGGKKKKKKKDKKHK--KDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEP 862

Query: 422 PAHPITRVPQEFQTPEQATELVHQLQEDYHRLLTK 456
            A P  +   E +  +   +L   L+E   R + K
Sbjct: 863 VAAPEPKKETESEAEDNLDDLEKHLREKALRSMRK 897



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 115/603 (19%), Positives = 194/603 (32%), Gaps = 84/603 (13%)

Query: 503  PQPRSAEWWPGPAEDPQASAASGWPSARGDLSPSSLTSMPTLGWLPENRDISEDQSSAEQ 562
            P P   E  P   E P+ S     PS +   S S +  +P    +PE ++ S +++S ++
Sbjct: 212  PAPEKKEKTP---ELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKE 268

Query: 563  TQALASQASQFLAKVESFERLIQAGRLMPQDQVKGFQRLKAAHAALEEEYLKACREQHPA 622
             +           K     R     R   + +     R +  H +    Y    R     
Sbjct: 269  KEK---------EKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRR 319

Query: 623  QPLAGSKGTPGRFDP-----------RRELEAEIYRLGSCLEELKEHIDQTQQEP----- 666
            +P    +  P R  P           RR   +     GS             ++P     
Sbjct: 320  RPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTS 379

Query: 667  EPPGSDSALDSTPALPCLHQPTHLPAPSGQAPMPAIKTSCPEPATTTAAASTGPCPLHVN 726
             PP     L  + + P   +  H P+P    P     +  P+ +  T  +     P   +
Sbjct: 380  SPPRKTRRLSPSASPP---RRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTS 436

Query: 727  VEVSSGNSEVEDRPQDPLARLRHKEL-QMEQVYHGLMERYLSVKSLPEAMRMEEEEEGEE 785
             +V+      +     P  + R  EL + E+   G M    SV+      R +   + ++
Sbjct: 437  GKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQ-----QRRQYRRQNQQ 491

Query: 786  EEEEEGGGDSLEVDGVAATPGKAEATRVLPRQCPVQ-AEKSHGAPLEEATEKMVSMKPPG 844
               + G   S E +    +  K        R  P + A  S     +E + +    + P 
Sbjct: 492  SSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPS 551

Query: 845  FQASLARDGHMSGLGKAEAAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPL 904
               +  R         + A PP     P PP  +   S      S             P 
Sbjct: 552  PPPTRRR------RSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRS-------------PS 592

Query: 905  HRGGGPHLEETWMASPETDSGFVG---SETSRVSPLTQTPEHRLSH-------ISTAGTL 954
             R   P ++  +  SP               R SP +  P+ R+SH        S     
Sbjct: 593  PRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASP-SPPPKRRVSHSPPPKQRSSPVTKR 651

Query: 955  AQPFAASVPRDGASYPKA---RGSLIPRRATEPSTPRSQAQRYLSSP--------SGPLR 1003
              P  +S  R G+S  ++     S  P +   PS PR +A +  SSP        S P R
Sbjct: 652  RSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPS-PRPRAPQTSSSPPPVRRGASSSPQR 710

Query: 1004 QRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPL----PNKTISPPPAPAPAAAPLPCGP 1059
            +++P+ S              + +     S Q +     ++++S  P PA    P P  P
Sbjct: 711  RQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSP 770

Query: 1060 TET 1062
             ++
Sbjct: 771  VQS 773



 Score = 31.6 bits (70), Expect = 5.8
 Identities = 63/284 (22%), Positives = 101/284 (35%), Gaps = 42/284 (14%)

Query: 175 GEQASGDKLSEHSEVNPSVELSPARSWSSGTVSLDHPSDSLDSTWE-GETDGPQPTALAE 233
           G+ A+ D + +  +     + S + S SS +   + P  S     E G      P+  A 
Sbjct: 471 GKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSAS 530

Query: 234 TLPEGPSHHLLSPDGRTGGSVARATPMEFQDSSAPPAQSPQHATDRWRRETTRFFCPQPK 293
             P        SP GR      R +P      S PP           RR  +    P P+
Sbjct: 531 PSPRKRQKET-SPRGRR-----RRSP------SPPPT----------RRRRSPSPAPPPR 568

Query: 294 EHIWKQTKTSPKPLPSRFIGSISPLNPQPRPTRQGRPLPRQ--GATLAGRSSSNAPKYGR 351
                  + +P P P R   S  P    P P R   P+ R+   +    R +++ P   +
Sbjct: 569 R------RRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPK 622

Query: 352 GQLNYPLPDFSKVG----PRVRFPKDESYRPPKSRSHNRKPQAPARPL-IFKSPAEIVQE 406
            + +   P   +V     P+ R       R P   S +RK  +P+R     +SP    + 
Sbjct: 623 RRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRH 682

Query: 407 VLLSSGEAALAKDTPPAHPITR----VPQEFQTPEQATELVHQL 446
                  A     +PP  P+ R     PQ  Q+P  +T  + ++
Sbjct: 683 SPSPRPRAPQTSSSPP--PVRRGASSSPQRRQSPSPSTRPIRRV 724


>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
          Length = 1499

 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 99/456 (21%), Positives = 152/456 (33%), Gaps = 84/456 (18%)

Query: 978  PRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAA--EMAVPGSEFEGHKRISEQ 1035
            P++   PS   +Q Q+  S   GP +  + +    + + +  + ++P S   G  R+S  
Sbjct: 832  PQKMLMPSQFPNQGQQGFSGGQGPYQAMSQDMGNTQDMFSPDQSSMPMSNV-GTTRLSHM 890

Query: 1036 PLPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQ---EEVSRLRLRLE 1092
            PLP              A  P G   + P+  L R   D  I   Q     +  L+    
Sbjct: 891  PLP-------------PASNPPGTVHSAPNRGLGRRPSDLTISINQMGSPGMGHLKSPTL 937

Query: 1093 DSLHQPLQGSPTR-------PASAFDRPARTRGRPADSPATWGSHYGSKSTERLPGEPRG 1145
              +H PL  SP+        P+     P+     P  SP   GS    +S    P   + 
Sbjct: 938  SQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLGSSLSVRSPTGSPSRLKS 997

Query: 1146 EEQIVP-PGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKRGV 1204
                VP PG   +  +++P   +     S+++ P L + S  + +  +       G R  
Sbjct: 998  PSMAVPSPGWVASPKTAMPSPGV-----SQNKQPPLNMNSSTTLSNMEQGTLPPSGPRSS 1052

Query: 1205 GSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGN---------GTVSCPHCRPIRTQDAGGA 1255
             SA  P      G          SP   P  N            + P   P+        
Sbjct: 1053 SSA--PPANPPSGLMNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPSSTPLYHNAIKTI 1110

Query: 1256 VTGD-------PLGPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSP 1308
             T D       PL PPP              PP+  GPG + S   +      A+ +P  
Sbjct: 1111 ATSDDELLPDRPLLPPPP-------------PPQGSGPGISNSQPSQMHLNSAAAQSPMG 1157

Query: 1309 KQRSKQAGSSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPY-------PPAAVYYAPA 1361
                 Q   S  PPP +       P+P P      S++P+ P        P  ++  AP 
Sbjct: 1158 MNLPGQQPLSHEPPPAML------PSPTPLG----SNIPLHPNAQGTGGPPQNSMMMAPG 1207

Query: 1362 GPTSAQPAAKWPPTASP----PPARRHRHSIQLDLG 1393
            GP S        P++S     PP  +  H      G
Sbjct: 1208 GPDSLNAPCGPVPSSSQMMPFPPRLQQPHGAMAPTG 1243



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 56/198 (28%), Positives = 78/198 (39%), Gaps = 35/198 (17%)

Query: 863  AAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPET 922
            A PPGP   P   G+        S+ S  GS    + P   +   G       W+ASP+T
Sbjct: 967  ANPPGPLKSPQVLGSSL------SVRSPTGSPSRLKSPSMAVPSPG-------WVASPKT 1013

Query: 923  DSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRAT 982
                 G   ++  PL       LS++   GTL      S PR  +S P A     P    
Sbjct: 1014 AMPSPGVSQNKQPPLNMNSSTTLSNME-QGTL----PPSGPRSSSSAPPANP---PSGLM 1065

Query: 983  EPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRI------SEQP 1036
             PS P      + SSP  P   + P  SL  T  ++ A+P S    H  I       ++ 
Sbjct: 1066 NPSLP------FTSSPD-PTPSQNP-LSLMMTQMSKYAMPSSTPLYHNAIKTIATSDDEL 1117

Query: 1037 LPNKTISPPPAPAPAAAP 1054
            LP++ + PPP P   + P
Sbjct: 1118 LPDRPLLPPPPPPQGSGP 1135



 Score = 32.0 bits (71), Expect = 4.4
 Identities = 38/135 (28%), Positives = 47/135 (34%), Gaps = 23/135 (17%)

Query: 1255 AVTGDPLGPPPADTLQCPLCGQVGSPPEADGPGS---------ATSGAEKATTRRKASST 1305
            +V G P GPPP      P  G  G       P           A + AE     R  S  
Sbjct: 205  SVPGAPHGPPPGLRPDAPGGGGGGGGVPGKPPSQFVYVFTTHLANTAAEAVLQGRADSIL 264

Query: 1306 PSPKQRSKQA--GSSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGP 1363
               +Q   +A    +P+ PP    L  + P+   P     S  P +P PP      P  P
Sbjct: 265  AYHQQNVPRAKLDQAPKVPPTPEPLPLSTPSAGTPQ----SQPPPLPPPP------PPAP 314

Query: 1364 TSAQPAAKWPPTASP 1378
             SA PA   PP   P
Sbjct: 315  GSAPPAL--PPEGPP 327


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 225/1119 (20%), Positives = 402/1119 (35%), Gaps = 177/1119 (15%)

Query: 253  SVARATPMEFQDSSAPPAQS------PQHATDRWRRETTRFFCPQPKEHIWKQTKTSPKP 306
            S++ ++P   Q S  PP +S      P+  +    R +     P PK+    ++KT    
Sbjct: 778  SLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQ----KSKT---- 829

Query: 307  LPSRFIGSISPLNPQPRPTRQGRPLPRQGATLAGRSSSNAPKYGRGQL--NYPLPDFSKV 364
             PSR   S S  +P P+  + G P PRQG+  + +++  +    R     + P P+    
Sbjct: 830  -PSR--QSHSSSSPHPK-VKSGTP-PRQGSITSPQANEQSVTPQRRSCFESSPDPELKSR 884

Query: 365  GPRVRFPKDESYRPPKSRSHNRKPQAPARPLIFKSPAEIVQEVLLSSGEAALAKDTPPAH 424
             P        S  PP+ +S     Q+P+R     SP   V+ ++     +     +P   
Sbjct: 885  TPSRHSCSGSS--PPRVKSSTPPRQSPSRS---SSPQPKVKAIISPRQRSHSGSSSPSPS 939

Query: 425  PITRVPQEFQTPEQATELVHQLQEDYHRLLTKYAEAENTIDQLRLGAKVNLFSDPPQPNH 484
             +T      +T  + +  V        RLL +Y+ + ++    ++         P  P  
Sbjct: 940  RVTS-----RTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKV--------KPETPPR 986

Query: 485  SIHTGMVPQGTKVLSFTIPQPR-SAEWWPGPAEDPQASAASGWPSA-------RGDLSPS 536
              H+G +    KV + T P P  S    P P E  + S     P +       +    P 
Sbjct: 987  QSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPG 1046

Query: 537  S----LTSMPTLGWLPENRDISEDQSSAEQTQALASQASQFLAKVESFERLIQAGRLMPQ 592
                 ++S+   G    + D   D SS E  Q+  S++    +K ++  +    GR    
Sbjct: 1047 ESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQS-HSESPSLQSKSQTSPK---GGRSRSS 1102

Query: 593  DQVKGFQRLKAAHAALEEEYLKACREQHPAQPLAGSKGTPGRFDPRRELEAEIYRLGSCL 652
              V       A+ + + ++     R +  A P+  S  +P +   R + ++  Y      
Sbjct: 1103 SPVTEL----ASRSPIRQD-----RGEFSASPMLKSGMSPEQ--SRFQSDSSSYPTVDSN 1151

Query: 653  EELKEHIDQTQQEPEPPGSDSALDSTPALPCLHQPTHLPAPSGQAPMPAI--KTSCPEPA 710
              L +   +T +  E        D+T A P   +    P P    P  ++  K +   P 
Sbjct: 1152 SLLGQSRLETAESKEKMALPPQEDAT-ASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPP 1210

Query: 711  TTTAAASTGPCPLHVNVEVSSGNS-----EVEDRPQDPLAR-LRHKELQMEQVYHGLMER 764
               + A + P     N  + + +      EV ++ ++P  + L H   +++++     E 
Sbjct: 1211 RERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFES 1270

Query: 765  YLSVKSLPEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATPGKAEATRVLPR--QCPVQA 822
               V+  P      ++ + +   E      ++EV  +A++ G    +         P++ 
Sbjct: 1271 SPEVEERPAVSLTLDQSQSQASLE------AVEVPSMASSWGGPHFSPEHKELSNSPLR- 1323

Query: 823  EKSHGAPLEEATEKMVSMKP-PGFQASLARDGHMSGLGKAEAAPPGPGVPPHPPGTKSAA 881
            E S G+PLE      +  +   GF + +  D +   L + E     P +      T+S+ 
Sbjct: 1324 ENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLET---DPSLDMKEQSTRSSG 1380

Query: 882  SHQSSMT--SLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSPLTQ 939
               S ++  ++E +G+S             P L+     +P  +     S       L +
Sbjct: 1381 HSSSELSPDAVEKAGMSSN------QSISSPVLDAV-PRTPSRERSSSASSPEMKDGLPR 1433

Query: 940  TPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATEPSTPRSQAQRYLSSPS 999
            TP  R    S+ G           RDG+  P +R SL          PR+ ++      S
Sbjct: 1434 TPSRRSRSGSSPGL----------RDGSGTP-SRHSLSGSSPGMKDIPRTPSRGRSECDS 1482

Query: 1000 GPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTISPPPAPAPAAAPLPCGP 1059
             P  +  P     R+ +                S   L NK ++P    + + + +    
Sbjct: 1483 SPEPKALPQTPRPRSRSP---------------SSPELNNKCLTPQRERSGSESSVDQKT 1527

Query: 1060 TETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGR 1119
                P    +R+G  Q   EL  + S       +S   P   + TR       P R R R
Sbjct: 1528 VARTPLGQRSRSGSSQ---ELDVKPSASPQERSESDSSPDSKAKTRT------PLRQRSR 1578

Query: 1120 PADSPATWGSHYGSKSTERLPGEPRGEEQIVPPGRQRARSSS---------VPREVLRLS 1170
               SP        S    R    P  +++  P    RA+S S          PR + R S
Sbjct: 1579 SGSSPEVDSKSRLSPRRSRSGSSPEVKDK--PRAAPRAQSGSDSSPEPKAPAPRALPRRS 1636

Query: 1171 LSSESEL---PSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVL 1227
             S  S     PS P  S  ++++ + P  +R  +RG  S+  P   +             
Sbjct: 1637 RSGSSSKGRGPS-PEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKS------------- 1682

Query: 1228 SPKAVPKGNGTVSCPHC-RPIRTQDAGGAVTGDP--LGPPPADTLQCPLCGQVGSPPEAD 1284
              +  P+   + S P   R  R      + +  P      P    + P    V SP  A+
Sbjct: 1683 --RTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSP---SVSSPEPAE 1737

Query: 1285 GPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPP 1323
                      +++ RR+++S+P  K  S++ G SP P P
Sbjct: 1738 --------KSRSSRRRRSASSPRTKTTSRR-GRSPSPKP 1767



 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 241/1122 (21%), Positives = 370/1122 (32%), Gaps = 145/1122 (12%)

Query: 184  SEHSEVNPSVELSPARSWSSGTVSLDHPS-DSLDSTWEGETDGPQPTALAETLPEGPSHH 242
            S  S   P  + S   S  S + S  HP   S     +G    PQ    + T P+  S  
Sbjct: 815  SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVT-PQRRSCF 873

Query: 243  LLSPD----GRTGG--SVARATPMEFQDSSAPPAQSPQHATDRWRRETTRFFCPQPKEHI 296
              SPD     RT    S + ++P   + SS PP QSP  ++   + +      P+ + H 
Sbjct: 874  ESSPDPELKSRTPSRHSCSGSSPPRVK-SSTPPRQSPSRSSSP-QPKVKAIISPRQRSH- 930

Query: 297  WKQTKTSPKPLPSRFIGSISPLNPQ---PRPTRQGRPLPRQGATLAGRSSSNAPKYGRGQ 353
                  S  P PSR     +P   +   P    + R LPR        S S++P   + +
Sbjct: 931  ----SGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYS-----HSGSSSPDT-KVK 980

Query: 354  LNYPLPDFSKVGPRVRFPKDESYRPPKSRSHNRKPQAPARPLIFKSPAEIVQEVLLSSGE 413
               P P  S  G    +PK ++  PP       K   P      KS   +VQ    S   
Sbjct: 981  PETP-PRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQE----KSKDSLVQSCPGSLSL 1035

Query: 414  AALAKD-TPPAHPITRVPQEFQTPEQATELVHQLQEDYHRLLTKYAEAENTIDQLRLGAK 472
             A  K  TPP      V       +  T   H+       +   ++E+ +   + +   K
Sbjct: 1036 CAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPK 1095

Query: 473  ----------VNLFSDPP--------QPNHSIHTGMVPQGTKVLSFTIPQP--------- 505
                        L S  P          +  + +GM P+ ++  S +   P         
Sbjct: 1096 GGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLG 1155

Query: 506  ----RSAEWWPGPAEDPQASAASGWPSARGDLSP--------SSLTSMPTLGWLPENRD- 552
                 +AE     A  PQ  A +  P  +   SP        SSL    TL   P  R  
Sbjct: 1156 QSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSG 1215

Query: 553  ISEDQSSAEQTQAL--ASQASQFLAKVESFERLIQAGRLMPQ-------------DQVKG 597
                  + EQ  AL  +SQ  + +  VE  E    AG+++               +    
Sbjct: 1216 AGSSPETKEQNSALPTSSQDEELMEVVEKSEE--PAGQILSHLSSELKEMSTSNFESSPE 1273

Query: 598  FQRLKAAHAALEEEYLKACREQHPAQPLAGSKGTPGRFDPRRELEAEIYR---LGSCLE- 653
             +   A    L++   +A  E      +A S G P      +EL     R    GS LE 
Sbjct: 1274 VEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEF 1333

Query: 654  --------ELKEHIDQTQQEPEPPGSDSALDSTPALPCLHQPTHLPAPSGQAPMP-AIKT 704
                    E+        +E       + L++ P+L    Q T     S     P A++ 
Sbjct: 1334 RNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEK 1393

Query: 705  SCPEPATTTAAASTGPCPLHVNVEVSSGNSEVEDR---PQDPLARLRHKELQMEQVYHGL 761
            +      + ++      P   + E SS  S  E +   P+ P  R R       +   G 
Sbjct: 1394 AGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGT 1453

Query: 762  MERYLSVKSLPEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATP---GKAEATRVLPRQC 818
              R+    S P    +         E +     S E   +  TP    ++ ++  L  +C
Sbjct: 1454 PSRHSLSGSSPGMKDIPRTPSRGRSECDS----SPEPKALPQTPRPRSRSPSSPELNNKC 1509

Query: 819  PVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLG-KAEAAPPGPGVPPHPPGT 877
                 +  G+      +K V+  P G ++   R G    L  K  A+P         P +
Sbjct: 1510 LTPQRERSGSE-SSVDQKTVARTPLGQRS---RSGSSQELDVKPSASPQERSESDSSPDS 1565

Query: 878  KSAASHQSSMTSLEGSG----ISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSETSR 933
            K+         S  GS        RL  +    G  P +++   A+P   SG   S   +
Sbjct: 1566 KAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPK 1625

Query: 934  VSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKA-----RGSLIPRRATEPSTPR 988
                   P    S  S+ G    P  +S       +P       RGS   R + EP T  
Sbjct: 1626 APAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGS---RSSPEPKTKS 1682

Query: 989  SQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTISPPPAP 1048
                R  SS S P   R    S     A+      S  E   R   +   + ++S P   
Sbjct: 1683 RTPPRRRSSRSSPELTRKARLSRRSRSAS------SSPETRSRTPPRHRRSPSVSSPEPA 1736

Query: 1049 APAAAPLPCGPTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPAS 1108
              + +        +  +   +R GR  +      + SR R R E +     +       S
Sbjct: 1737 EKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQS 1796

Query: 1109 AFDRPARTRGRP-ADSPATWGSHYGSKSTERLPGEP------RGEEQIVPPGRQRARSSS 1161
               R  R+R R         GS Y S+S  R           RG  +  P  R+R+RS +
Sbjct: 1797 TSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRT 1856

Query: 1162 VP----REVLRLSLSSESELPS-LPLFSEKSKTTKDSPQAAR 1198
             P    R   R S ++     S  PL S +   ++ SP + R
Sbjct: 1857 SPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRR 1898



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 213/1082 (19%), Positives = 343/1082 (31%), Gaps = 201/1082 (18%)

Query: 226  PQPTALAETLPEGPS---HHLLSPDGRTGGSVARATPMEFQ-----DSSAPPAQS----- 272
            P P   A+T P GPS        P  ++  S+ ++ P          SS PP +S     
Sbjct: 995  PYPKVKAQT-PPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVS 1053

Query: 273  -----------PQHATDRWRRETTRFFCPQPKEHIWKQTKTSPKPLPSRFIGSISPLNPQ 321
                       P H +D    E  +     P   +  +++TSPK   SR    ++ L  +
Sbjct: 1054 SLQLKGQSQTSPDHRSDTSSPEVRQSHSESPS--LQSKSQTSPKGGRSRSSSPVTELASR 1111

Query: 322  PRPTRQGRPLPRQGATLAGRSSSNAPKYGRGQLNYPLPDFSKVGPRVRFPKDESYR---- 377
              P RQ R        L    S    ++     +YP  D + +  + R    ES      
Sbjct: 1112 S-PIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMAL 1170

Query: 378  PPKSRSHNRKPQA------------PARPLIFKSPAEIVQEVLLSSGEAALAKDTPPAHP 425
            PP+  +    P+             P   L+FK            +G +   K+   A P
Sbjct: 1171 PPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALP 1230

Query: 426  ITRVPQEF-----QTPEQATELVHQLQEDYHRLLTKYAEAENTIDQLRLGAKVNLFSDPP 480
             +   +E      ++ E A +++  L  +   + T   E+   +++      V+L  D  
Sbjct: 1231 TSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEER---PAVSLTLDQS 1287

Query: 481  QPNHSIHTGMVPQGTKVLSFTIPQPRSAEWWPGPAEDPQASAASGWPSARGDL-SPSSLT 539
            Q   S+    VP               A  W GP   P+    S  P       SP    
Sbjct: 1288 QSQASLEAVEVPS-------------MASSWGGPHFSPEHKELSNSPLRENSFGSPLEFR 1334

Query: 540  SMPTLGWLPENRDISEDQSSAEQTQALASQASQFLAKVESFERLIQAGRLMPQDQVKGFQ 599
            +   LG          + ++   ++        FL ++E+   L    +     +  G  
Sbjct: 1335 NSGPLG---------TEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQ---STRSSGHS 1382

Query: 600  RLKAAHAALEEEYLKACREQHPAQPLAGSKGTPGRFDPRRELEAEIYRLGSCLEELKEHI 659
              + +  A+E+  + +   Q  + P+  +        P RE  +      +   E+K+ +
Sbjct: 1383 SSELSPDAVEKAGMSS--NQSISSPVLDAVPRT----PSRERSSS-----ASSPEMKDGL 1431

Query: 660  DQTQQEPEPPGSDSALDSTPALPCLHQ--------------PTHLPAPSGQAPMPAIKTS 705
             +T       GS   L      P  H               P+   +    +P P     
Sbjct: 1432 PRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQ 1491

Query: 706  CPEPATTTAAAS--TGPCPLHVNVEVSSGNSEVEDRP--QDPLARLRHKELQMEQVYHGL 761
             P P + + ++      C L    E S   S V+ +   + PL +        E      
Sbjct: 1492 TPRPRSRSPSSPELNNKC-LTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQE------ 1544

Query: 762  MERYLSVKSLPEAMRMEEEEEGEEEE--------EEEGGGDSLEVDGVA------ATPGK 807
                L VK         E +   + +        +    G S EVD  +      +  G 
Sbjct: 1545 ----LDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGS 1600

Query: 808  AEATRVLPRQCPVQAEKSHGAPLEEA-TEKMVSMKPPGFQASLARDGHMSGLGKAEAAPP 866
            +   +  PR  P     S  +P  +A   + +  +     +S  R     G    E++P 
Sbjct: 1601 SPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPE 1660

Query: 867  GPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGF 926
                  HPP  KS  + + S +S E    S   P++   R   P L      S  + S  
Sbjct: 1661 ------HPP--KSRTARRGSRSSPEPKTKSRTPPRRRSSRSS-PELTRKARLSRRSRSAS 1711

Query: 927  VGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATEPST 986
               ET   +P    P HR S   ++   A+   +S  R  AS P+ + +   RR   PS 
Sbjct: 1712 SSPETRSRTP----PRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTT--SRRGRSPSP 1765

Query: 987  PRSQAQRYLS---------------SPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHK- 1030
                 QR  S               S S     R    S  R+        GS +     
Sbjct: 1766 KPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSP 1825

Query: 1031 ------RISEQPLPNKTISPPPA---------PAP------AAAPLPCGPTETIPSFLLT 1069
                  R S +    ++ +PP +         PAP       A+P     + +    +  
Sbjct: 1826 ARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISR 1885

Query: 1070 RAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGS 1129
            R  R +        VSR R R   S+ +    S   P S      R R R    P T   
Sbjct: 1886 RRSRSRT-----SPVSRRRSRSRTSVTRRRSRSRASPVS------RRRSRSRTPPVT--- 1931

Query: 1130 HYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKT 1189
                +S  R P   R      PP  +R   S  P    R S S  S +      S  S  
Sbjct: 1932 --RRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPV 1989

Query: 1190 TK 1191
            T+
Sbjct: 1990 TR 1991



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 309/1496 (20%), Positives = 481/1496 (32%), Gaps = 240/1496 (16%)

Query: 48   PNATSPELLEDFRLAQQHLPPLEWDPHPQPDGHQDSESGETSGEEAEAEDVDSPASSHEP 107
            P AT+P   E      +  P  +  P   P+    S S E+S    +   V   ASS   
Sbjct: 380  PLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPE 439

Query: 108  L---AWLPQQGRQLDMTEEEPDGTLGSLEVEEAGES--SSRLGYEAGLSLEGHGNT---S 159
                A  P   R++  +    + + G  + +++     S R+G     +    G +   +
Sbjct: 440  SPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRT 499

Query: 160  PMALGHGQARG--WVAS-GEQASGDKLSEHSEVNPSVELSPARSWSSGTVSLDHPSDSLD 216
            P   GH ++R   W  S   Q  G   S            P  S S  T           
Sbjct: 500  PTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSR---- 555

Query: 217  STWEGETDGPQPTALAETLPEGPSHHLLSPDGRTGGSVARATPMEFQDSSAPPAQSPQHA 276
            S   G +    P     +    P+        R G S +R TP   +  S  P +    +
Sbjct: 556  SARRGRSHSRSPATRGRSRSRTPA--------RRGRSRSR-TPARRRSRSRTPTRRRSRS 606

Query: 277  TDRWRRETTRFFCPQPKEHIWKQT--KTSPKPLPSRFIGSISPLNPQPR-------PTRQ 327
                RR  +R   P  +    +    + S    P+R  G      P  R       P R+
Sbjct: 607  RTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARR 666

Query: 328  GRPLPRQGATLAGRSSSNAP-KYGRGQLNYPLPDFSKVGPRVRFPKDESYRPP------- 379
            GR   R  A  +GRS S  P + GR +   P    S+    VR  +  S  P        
Sbjct: 667  GRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGS 726

Query: 380  ------KSRSHNRKPQAPARPLIFKSPAEIVQEVLLSS------GEAALAKDTPPAHPIT 427
                  KSR+  R+ ++ + P + KS     +   LSS         +L +    + P  
Sbjct: 727  SSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCP 786

Query: 428  RVPQEFQTPEQATELVHQLQEDYHRLLTKYAEAENTIDQLRLGAKVNLFSDPPQ-----P 482
            +  Q+ QTP + +       +   R   + + + +              S PP+     P
Sbjct: 787  K--QKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSS--------------SPPPKQKSKTP 830

Query: 483  NHSIHTGMVPQGTKVLSFTIPQPRSAEWWPGPAEDPQASAASGWPSARGDLSPSSLTSMP 542
            +   H+   P   KV S T P+        G    PQA+  S  P  R     S   S P
Sbjct: 831  SRQSHSSSSPH-PKVKSGTPPR-------QGSITSPQANEQSVTPQRR-----SCFESSP 877

Query: 543  TLGWLPENRDISEDQSSAEQTQALASQASQFLAKVESFERLIQAGRLMPQDQVKGFQRLK 602
                 PE +  +  + S        S +S    K  +  R   +    PQ +VK      
Sbjct: 878  D----PELKSRTPSRHS-------CSGSSPPRVKSSTPPRQSPSRSSSPQPKVK------ 920

Query: 603  AAHAALEEEYLKACREQHPAQPLAGSKGTPGR---FDPRRELEAEIYRLGSCLEELKEHI 659
               A +            P+     S+ TP R     P   +E+   RL           
Sbjct: 921  ---AIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVES---RLLPRYSHSGSSS 974

Query: 660  DQTQQEPEPPGSDSALDSTPALPCLHQPTHLPAPSGQAPMPAIKTSCPEPATTTAAASTG 719
              T+ +PE P   S   S    P +   T  P PS    +   K+ CP+  +  +   + 
Sbjct: 975  PDTKVKPETPPRQSHSGSISPYPKVKAQTP-PGPS----LSGSKSPCPQEKSKDSLVQSC 1029

Query: 720  PCPLHVNVEVSSGNSEVEDRPQDPLARLRHKELQMEQVYHGLMERYLSVKSLPEAMRMEE 779
            P  L +   V S     E      ++ L+ K        H       S  S PE  +   
Sbjct: 1030 PGSLSLCAGVKSSTPPGES--YFGVSSLQLKGQSQTSPDH------RSDTSSPEVRQSHS 1081

Query: 780  EEEGEEEEEEEG--GGDSLEVDGVAATPGKAEATRVLPRQCPVQAEKSHGAPLEEATEKM 837
            E    + + +    GG S     V     ++   +           KS  +P +   +  
Sbjct: 1082 ESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSD 1141

Query: 838  VSMKPPGFQASLARDGHMSGLGKAE--AAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGI 895
             S  P     SL     +      E  A PP       PP  K   S        E S +
Sbjct: 1142 SSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLV 1201

Query: 896  -SERLPQKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTL 954
              + L   P  R G     ET   +    +     E   V   ++ P         AG +
Sbjct: 1202 FKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEP---------AGQI 1252

Query: 955  AQPFAASVPRDGASYPKARGSLIPRRATEPSTPRSQAQRYLSS---PSGPLRQRAPNFSL 1011
                ++ +     S  ++   +  R A   +  +SQ+Q  L +   PS       P+FS 
Sbjct: 1253 LSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSP 1312

Query: 1012 ERTLAAEMAVPGSEFEGHKRISEQPLPNKTISPP---PAPAPAAAPLPCG---------- 1058
            E                HK +S  PL   +   P       P    +  G          
Sbjct: 1313 E----------------HKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLN 1356

Query: 1059 -----PTETIPSFLL----TRAGRDQAICELQEEVSRLRLRLEDSLHQP----LQGSPTR 1105
                   ET PS  +    TR+    +     + V +  +    S+  P    +  +P+R
Sbjct: 1357 GPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSR 1416

Query: 1106 PASAF-------DRPARTRGRPADSPATWGSHYGSKSTER--LPGEPRGEEQIV-PPGRQ 1155
              S+        D   RT  R + S ++ G   GS +  R  L G   G + I   P R 
Sbjct: 1417 ERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRG 1476

Query: 1156 RARSSSVPR-EVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVT 1214
            R+   S P  + L  +    S  PS P  + K  T    PQ  R G           R  
Sbjct: 1477 RSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLT----PQRERSGSESSVDQKTVARTP 1532

Query: 1215 F--RGQYTGHEYHVLSPKAVPKGNG-TVSCPHCR-----PIRTQDAGGAVTGDPLGPPPA 1266
               R +    +   + P A P+    + S P  +     P+R +   G+        P  
Sbjct: 1533 LGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGS-------SPEV 1585

Query: 1267 DTLQ--CPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPK--QRSKQAGSSPRPP 1322
            D+     P   + GS PE      A   A+  +        P+P+   R  ++GSS +  
Sbjct: 1586 DSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSK-- 1643

Query: 1323 PGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPPPAR 1382
                        P+P   +   S P   +PP +        +S +P  K   + +PP  R
Sbjct: 1644 ---------GRGPSPEGSSSTESSP--EHPPKSRTARRGSRSSPEPKTK---SRTPPRRR 1689

Query: 1383 RHRHSIQLDLGDLEELNKALSRAVQAAESVRSTT--RQMRSSLSADLRQAHSLRGS 1436
              R S +L     +      SR+  ++   RS T  R  RS   +    A   R S
Sbjct: 1690 SSRSSPEL---TRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSS 1742



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 66/275 (24%), Positives = 97/275 (35%), Gaps = 18/275 (6%)

Query: 1108 SAFD--RPARTRGRPADSPATWGSHYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPRE 1165
            S+FD  R AR   +PA  P    S     S+ R P   + +++      +R+ SSS  RE
Sbjct: 149  SSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRE 208

Query: 1166 VLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYH 1225
              + S   +    S     +    T  S + ++D KR    +  P   + R         
Sbjct: 209  RKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHR------ 262

Query: 1226 VLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSPPEADG 1285
              S  A    +   S    R    +    A+ G    P PA   +    G+  +P    G
Sbjct: 263  --STSADSASSSDTSRSRSRSAAAKTHTTALAGR--SPSPASGRR----GEGDAPFSEPG 314

Query: 1286 PGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAP-PAFAYIS 1344
              S    +   T  ++ SS    K + K+  S+ RP P     +T P  PAP P  A   
Sbjct: 315  TTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERH 374

Query: 1345 SVPIMPYPPAAVYYAPAGPTS-AQPAAKWPPTASP 1378
                 P     +   P  P S A P     P  SP
Sbjct: 375  GGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSP 409



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 120/564 (21%), Positives = 199/564 (35%), Gaps = 82/564 (14%)

Query: 866  PGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGG-GPHLEETWMASPETDS 924
            PGP +P H   T    +H  S  +L  + IS    + P      G     + + +P    
Sbjct: 2160 PGPRIPDHQR-TSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLM 2218

Query: 925  GFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLI-PRRATE 983
                +  + ++           ++++A T A P A ++         A  +L  PR A  
Sbjct: 2219 SLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVA 2278

Query: 984  PSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTIS 1043
            PS       R   +P+ P    A N +  RT AA  A+  +        +  P  ++T  
Sbjct: 2279 PSAVNLADPR---TPTAP----AVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRT-- 2329

Query: 1044 PPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSP 1103
             P APA A    P     T P   +  AG   A        S    R+  +L      SP
Sbjct: 2330 -PQAPASANLVGPRSAHATAP---VNIAGSRTAAA--LAPASLTSARMAPALSGANLTSP 2383

Query: 1104 TRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVP 1163
              P SA++R +     P    A       S++    P + R   +  P     +R    P
Sbjct: 2384 RVPLSAYERVSGRTSPPLLDRAR------SRTPPSAPSQSRMTSERAPS--PSSRMGQAP 2435

Query: 1164 REVLRLSLSSESELPSLPLFSEKSKT--TKDSPQAARDGKRGVGSAGWPDRVTFRGQYTG 1221
             + L      +   P    FS++S+    + +P A   G + + S       +  G +  
Sbjct: 2436 SQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVA---GSQSLSSGAVATTTSSAGDH-- 2490

Query: 1222 HEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSPP 1281
                          NG +S P         A G    D +G PPA T             
Sbjct: 2491 --------------NGMLSVP---------APGVPHSD-VGEPPAST------------- 2513

Query: 1282 EADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAFA 1341
             A  P SA +  + A  RR +SS+ S    S  + SS          +++  + +  + +
Sbjct: 2514 GAQQP-SALAALQPAKERRSSSSSSSSSSSSSSSSSSS---------SSSSSSGSSSSDS 2563

Query: 1342 YISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPPPARRHRHSIQLDLGDLEELNKA 1401
              SS+P+ P    A+   P+   + + A +      P PA+R R S           + +
Sbjct: 2564 EGSSLPVQP--EVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSS 2621

Query: 1402 LSRAVQAAESVRSTTRQMRSSLSA 1425
             S +  ++ S  S++    SS S+
Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSS 2645



 Score = 38.1 bits (87), Expect = 0.062
 Identities = 107/536 (19%), Positives = 173/536 (32%), Gaps = 64/536 (11%)

Query: 804  TPGKAEATRVLPRQCPVQAEKSHGAPLEEATEKMVSM---KPPGFQASLARDGHMSGLGK 860
            TP  A A  +   +  V     + A     T   V++   + P   A+L+  G  SG   
Sbjct: 2261 TPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTG--SGTPP 2318

Query: 861  AEAAPPGPGVPPHPPGTKSA----ASHQSSMTSLEGSGISERLPQKPLHRGG-GPHLEET 915
              A  P     P  P + +     ++H ++  ++ GS  +  L    L      P L   
Sbjct: 2319 TAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGA 2378

Query: 916  WMASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKAR-- 973
             + SP        S   RVS  T  P   L    +    + P  + +  + A  P +R  
Sbjct: 2379 NLTSPRVPL----SAYERVSGRTSPP--LLDRARSRTPPSAPSQSRMTSERAPSPSSRMG 2432

Query: 974  ----GSLIPRRATEPSTPRSQA----QRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSE 1025
                 SL+P    +P +P   A     R L + + P+   A + SL     A       +
Sbjct: 2433 QAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPV---AGSQSLSSGAVATTTSSAGD 2489

Query: 1026 FEGHKRISEQPLPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQEEVS 1085
              G   +    +P+  +  PPA   A  P      +       + +    +        S
Sbjct: 2490 HNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSS 2549

Query: 1086 RLRLRLEDSLHQPLQGS--PTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLPGEP 1143
                    S     +GS  P +P  A  R       P+ +PA           E  P EP
Sbjct: 2550 SSSSSSSGSSSSDSEGSSLPVQPEVALKRV------PSPTPAP-----KEAVREGRPPEP 2598

Query: 1144 RGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKRG 1203
               ++        + SSS        S SS S   S    S  S ++  SP  A+ G + 
Sbjct: 2599 TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQA 2658

Query: 1204 VGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDPLGP 1263
            +                       SPK  P G      P  +PI +     +++  P+  
Sbjct: 2659 LPKPA-------------------SPKKPPPGERRSRSPR-KPIDSLRDSRSLSYSPVER 2698

Query: 1264 PPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSP 1319
                    P   Q  S       G    G  ++ + ++   TPSP+    ++  SP
Sbjct: 2699 RRPSPQPSPRDQQSSSSERGSRRGQR--GDSRSPSHKRRRETPSPRPMRHRSSRSP 2752



 Score = 37.4 bits (85), Expect = 0.10
 Identities = 92/414 (22%), Positives = 147/414 (35%), Gaps = 70/414 (16%)

Query: 945  LSHISTAGTLAQPFAASVPRDGASYPKARGS--LIPRRATEPSTP----RSQAQRYLSSP 998
            L+ +S  G+   P AA+ P    + P+A  S  L+  R+   + P     S+    L+  
Sbjct: 2306 LAALSLTGSGTPPTAANYPSSSRT-PQAPASANLVGPRSAHATAPVNIAGSRTAAALAPA 2364

Query: 999  SGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPN-----KTISPPPAPAPAA- 1052
            S    + AP  S      A +  P      ++R+S +  P      ++ +PP AP+ +  
Sbjct: 2365 SLTSARMAPALS-----GANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRM 2419

Query: 1053 ----APLPCGPTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPAS 1108
                AP P       PS  L    +DQ    +    S  + R   +   P+ GS +  + 
Sbjct: 2420 TSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSD-QSRCLIAQTTPVAGSQSLSSG 2478

Query: 1109 AFDRPARTRGRPADSPATWGSHYGSKSTERLPGEPRGEEQIVPPGRQRARSSSV-----P 1163
            A           A + ++ G H G  S    PG P  +    PP    A+  S      P
Sbjct: 2479 AV----------ATTTSSAGDHNGMLSVPA-PGVPHSDVG-EPPASTGAQQPSALAALQP 2526

Query: 1164 REVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHE 1223
             +  R S SS S   S    S  S ++  S  ++ D + G      P+    R       
Sbjct: 2527 AKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE-GSSLPVQPEVALKR------- 2578

Query: 1224 YHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSPPEA 1283
              V SP   PK            +R         G P  P PA   +        S   +
Sbjct: 2579 --VPSPTPAPK----------EAVRE--------GRPPEPTPAKRKR--RSSSSSSSSSS 2616

Query: 1284 DGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAP 1337
                S++S +  +++   +SS+ S    S  + S  +P P       +P  P P
Sbjct: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPP 2670



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 34/110 (30%), Positives = 49/110 (44%), Gaps = 6/110 (5%)

Query: 1092 EDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLPGEPRGEEQIVP 1151
            ED      + S TRP+ + +R +     PA +P     H G  S + L   P  +E + P
Sbjct: 336  EDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGG--SPQPLATTPLSQEPVNP 393

Query: 1152 PGR---QRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAAR 1198
            P      R RS     E L  S SSES  PS P  ++ S+    SP++ +
Sbjct: 394  PSEASPTRDRSPPKSPEKLPQSSSSESSPPS-PQPTKVSRHASSSPESPK 442



 Score = 35.4 bits (80), Expect = 0.40
 Identities = 62/264 (23%), Positives = 92/264 (34%), Gaps = 40/264 (15%)

Query: 1113 PARTRGRPADSPATWGSHYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLS 1172
            P R R + +            K   R P  P+ + +     R+R+RS++   +  R   S
Sbjct: 205  PRRERKKSSKKKKHRSESESKKRKHRSP-TPKSKRKSKDKKRKRSRSTTPAPKSRRAHRS 263

Query: 1173 SESELPSLPLFSE--------KSKTTK---DSPQAARDGKRGVGSAGWPDRVTFRGQYTG 1221
            + ++  S    S         K+ TT     SP  A  G+RG G A + +  T   Q   
Sbjct: 264  TSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPA-SGRRGEGDAPFSEPGTTSTQRPS 322

Query: 1222 HEYHVLSPKAVP-------KGNGTVSCPHCRPIRTQDAGGAVTGDPL-----GPPPADTL 1269
                     + P       K   + + P   P R+          PL     G  P    
Sbjct: 323  SPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLA 382

Query: 1270 QCPLCGQVGSPPEADGPGSATSGAEKATTRRKASST------PSPKQRSKQAGSSPRPPP 1323
              PL  +  +PP    P    S  +      ++SS+      P P + S+ A SSP  P 
Sbjct: 383  TTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESP- 441

Query: 1324 GLWYLATAPPAPAPPAFAYISSVP 1347
                     PAPAP +   ISS P
Sbjct: 442  --------KPAPAPGSHREISSSP 457



 Score = 34.7 bits (78), Expect = 0.68
 Identities = 45/168 (26%), Positives = 61/168 (36%), Gaps = 21/168 (12%)

Query: 1279 SPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAPP 1338
            SPP  D   S T  +  + +R  +   PSP  R  QA S    PP        P +P P 
Sbjct: 2398 SPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPA----QDQPRSPVPS 2453

Query: 1339 AFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTAS----------PPPARRHRHSI 1388
            AF+  S   I    P       AG  S    A    T+S          P P   H    
Sbjct: 2454 AFSDQSRCLIAQTTPV------AGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVG 2507

Query: 1389 QLDLGDLEELNKALSRAVQAAESVRSTTRQMRSSLSADLRQAHSLRGS 1436
            +       +   AL+ A+Q A+  RS++    SS S+    + S   S
Sbjct: 2508 EPPASTGAQQPSALA-ALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS 2554



 Score = 30.8 bits (68), Expect = 9.8
 Identities = 55/245 (22%), Positives = 87/245 (35%), Gaps = 40/245 (16%)

Query: 158  TSPMALGHGQARGWVASGEQASGDKLSEHSEVNPSVELSPARSWSSGTVSLDHPSDSLDS 217
            T+P+A     + G VA+   ++GD     S   P V  S           +  P  S   
Sbjct: 2466 TTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHS----------DVGEPPAS--- 2512

Query: 218  TWEGETDGPQPTALAETLP----------EGPSHHLLSPDGRTGGSVARATPMEFQDSSA 267
                 T   QP+ALA   P             S    S    +  S +  +     + S+
Sbjct: 2513 -----TGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSS 2567

Query: 268  PPAQSPQHATDRWRRETTRFFCPQPKEHIWKQTKTSPKPLPSRFIGSISPLNPQPRPTRQ 327
             P Q P+ A  R    T     P PKE +  +    P+P P++     S  +     +  
Sbjct: 2568 LPVQ-PEVALKRVPSPT-----PAPKEAV--REGRPPEPTPAKRKRRSSSSSSSSSSSSS 2619

Query: 328  GRPLPRQGATLAGRSSSNAPKYGRGQLNYPLPDFSKVGPRVRFPKDES-YRPPKSRSHNR 386
                    ++ +  SSS++        + P P  +K GP+   PK  S  +PP     +R
Sbjct: 2620 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP--AKPGPQA-LPKPASPKKPPPGERRSR 2676

Query: 387  KPQAP 391
             P+ P
Sbjct: 2677 SPRKP 2681


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 124/490 (25%), Positives = 164/490 (33%), Gaps = 107/490 (21%)

Query: 968  SYPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMA--VPGSE 1025
            +Y   RG    +RA EP   +      LS PSG     +P     R   +E     PG  
Sbjct: 187  NYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGE-EGLSPGGKRRRGCNSEQTGLPPGL- 244

Query: 1026 FEGHKRISEQPLPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRAG------------- 1072
                      PLP   + PPP P P   P P     T P F LT+ G             
Sbjct: 245  ----------PLPPPPLPPPPPP-PPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPE 293

Query: 1073 -RDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHY 1131
             +  A  E QE+    R  L      P       P      PA   G P   P    SH 
Sbjct: 294  RKGSAPPERQEQ----RHSLPHPYPYPAPAYTAHPPGHRLVPAAPPG-PGPRPPGAESH- 347

Query: 1132 GSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTK 1191
            G     R PG    E ++    R R  SS  P         + S  P LP     + T+ 
Sbjct: 348  GCLPATRPPGSDLRESRV---QRSRMDSSVSPAATTACVPYAPSRPPGLP----GTTTSS 400

Query: 1192 DSPQAARDGKRGV-GSAGWPDRVTFRGQYTGHEYH-VLSPKAVPKGNGTVSCPHCRPIRT 1249
             S  ++  G RGV  + G P    ++       +H  L P A       +  P   P  +
Sbjct: 401  SSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLS 460

Query: 1250 QDAGGAVTGDP------LGPPPADTLQCPLC---------------GQVGSP-------P 1281
               G +    P        PPP   L+ P C               G  G P       P
Sbjct: 461  LPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLP 520

Query: 1282 EADG----PGSATS-GAEKA-------TTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLA 1329
              +G    P S  S G + +       T    +S++ S    S  AG    PPP   YLA
Sbjct: 521  HREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPP--YLA 578

Query: 1330 TA------PPAPA-----PPAFAYISSVPIMPYPPAAVYYAPAG----PTSAQPAAKWPP 1374
             +      PP+PA     PP      ++P  P PP++ +   +G    P S +P   +P 
Sbjct: 579  RSIDPLPRPPSPAQNPQDPPLVPLTLALP--PAPPSSCHQNTSGSFRRPESPRPRVSFPK 636

Query: 1375 T----ASPPP 1380
            T      PPP
Sbjct: 637  TPEVGPGPPP 646



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 141/638 (22%), Positives = 209/638 (32%), Gaps = 150/638 (23%)

Query: 823  EKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGKAEAAPPGPGVPPHPPGTKS--- 879
            E+   AP  E  E+  S+  P    + A   H  G     AAPPGPG  P PPG +S   
Sbjct: 293  ERKGSAP-PERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPG--PRPPGAESHGC 349

Query: 880  -------------AASHQSSM-TSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSG 925
                         +   +S M +S+  +  +  +P  P    G P    +  +S  +++G
Sbjct: 350  LPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTG 409

Query: 926  FVGSETSRVSPLT---QTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRAT 982
              G E +   P     QTP   +SH    G  A   ++  P  GA       SL P  ++
Sbjct: 410  LRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAH--SSRKPFLGAPAATPHLSLPPGPSS 467

Query: 983  EPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNK-- 1040
             P  P     R L  P  P   + P     R     +       EG  R +  PLP++  
Sbjct: 468  PPPPP---CPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREG 524

Query: 1041 ---------------TISPPPAPAPAA----------APLPCGPTETIPSFLLTRAGRDQ 1075
                           + +PP  P P            +  P GP    P   L R     
Sbjct: 525  FLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLAR----- 579

Query: 1076 AICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKS 1135
            +I  L    S  +   +  L       P  P S+  +      R  +SP    S    K+
Sbjct: 580  SIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSF--PKT 637

Query: 1136 TERLPGEPRG----EEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTK 1191
             E  PG P G      Q VPPG        +P    RL      + P  PL  +  +  +
Sbjct: 638  PEVGPGPPPGPLSKAPQPVPPG-----VGELPARGPRL-----FDFPPTPLEDQFEEPAE 687

Query: 1192 DSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQD 1251
                                                  K +P G   +       IR ++
Sbjct: 688  F-------------------------------------KILPDGLANIMKMLDESIRKEE 710

Query: 1252 -----AGGAVTGDPLGPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTP 1306
                   G     PL  P A +LQ P       P +     +A + A   TT    ++T 
Sbjct: 711  EQQQHEAGVAPQPPLKEPFA-SLQSPF------PTDTAPTTTAPAVAVTTTTTTTTTTTA 763

Query: 1307 SPKQRSKQAGSSPRPPPGLWYLATA---PPAPAPPAFAYI-------------------S 1344
            + ++  K   + P PPP   +   +   PP P PP+ A +                   +
Sbjct: 764  TQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGA 823

Query: 1345 SVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPPPAR 1382
            +V   P P     Y+P  P+    A   PPT++ P A+
Sbjct: 824  AVSTRPGPLPTTQYSPGPPSG---ATALPPTSAAPSAQ 858



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 130/576 (22%), Positives = 185/576 (32%), Gaps = 131/576 (22%)

Query: 648  LGSCLEELKEHIDQTQQEPEPPGSDSALDSTPALPC-LHQPTHLPAPSGQAPMPAI---K 703
            L   ++ L       Q   +PP     L   PA P   HQ T       ++P P +   K
Sbjct: 577  LARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPK 636

Query: 704  TSCPEPATTTAAASTGPCPLHVNV-EVSSGNSEVEDRPQDPLARLRHKELQMEQVYHGLM 762
            T    P       S  P P+   V E+ +    + D P  PL     +  + + +  GL 
Sbjct: 637  TPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLA 696

Query: 763  ERYLSVKSLPEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATPGKAEATRVLPRQCPVQA 822
                 +K L E++R EEE++  E              GVA  P   E    L    P   
Sbjct: 697  N---IMKMLDESIRKEEEQQQHEA-------------GVAPQPPLKEPFASLQSPFPTDT 740

Query: 823  EKSHGAPL------------EEATEKMVSMKPPGFQASLARDGHMSGLGKAEAAPPGPGV 870
              +  AP               AT++     PP                 A+  PP    
Sbjct: 741  APTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPL---------AKFPPPSQPQ 791

Query: 871  PPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGG------PHLEETWMASPETDS 924
            PP PP    A+  +S  + LEG        QK  +RG G      P    T   SP   S
Sbjct: 792  PPPPPPPSPASLLKSLASVLEG--------QKYCYRGTGAAVSTRPGPLPTTQYSPGPPS 843

Query: 925  GFVGSETSRVSPLTQ-TPEHRLSHISTAGTLAQPFA---------------ASVPRDGAS 968
            G      +  +P  Q +P+   S  S   T   P+A                + P    S
Sbjct: 844  GATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLS 903

Query: 969  YPKARG----------------SLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLE 1012
             P AR                   + R AT+P+ P   A+    + SG  R   P  + E
Sbjct: 904  LPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAE---PADSGTERLLPPAQAKE 960

Query: 1013 RTLAAEMAVPGS----------EFEGHKRISEQPLPNKTISPPPAPAPAAAPLPCGPTET 1062
                   AV GS          E   H+R  +  +  +                      
Sbjct: 961  EA-GGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRR---------------------- 997

Query: 1063 IPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQG-SPTRPASAFDRPARTRGRPA 1121
                   R GR +A  ++ +E SR  L   D   + +QG   +RP       A+    PA
Sbjct: 998  ------PREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPA 1051

Query: 1122 DSPATWGSHYGSKSTERLPGEPRGEEQIVPPGRQRA 1157
               A   S   +  +  +PG+   EE   PPG  RA
Sbjct: 1052 PPSAPAPSAQPTPPSASVPGKKAREEAPGPPGVSRA 1087



 Score = 37.4 bits (85), Expect = 0.10
 Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 5/89 (5%)

Query: 1253 GGAVTGDPLGPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRS 1312
            G AV+  P   P       P  G    PP +  P +  S    A++  + S++  P  R 
Sbjct: 822  GAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARE 881

Query: 1313 KQAGSSPRPPPGLWYLATAPPAP--APPA 1339
            ++AG  P P P      T PP P   PPA
Sbjct: 882  RRAGEEPVPGP---MTPTQPPPPLSLPPA 907


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 140/625 (22%), Positives = 213/625 (34%), Gaps = 123/625 (19%)

Query: 829  PLEEATEKMVSMKPPGFQASLARDGHMSGLGKAEAAPPGPGVPPHPPGTKSAASHQSSMT 888
            PL  A    V+++  G  ++   D   +G G     P   G PPH    +    H S   
Sbjct: 2244 PLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSP 2303

Query: 889  S-------LEGSGISERLPQKPLHRGGGPHLE---ETWMASPETDSGFVGSETSRVSPLT 938
            S        EG  ++    + P  +G GP      E  M +   +    G+  +  S  T
Sbjct: 2304 SNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGAT 2363

Query: 939  QTPEHR-------LSHISTAGTLAQPFAASVPRD--GASYPKARGS-LIPRRATEPSTPR 988
            + P          L   +   + A  F +  P+    AS+   +G  L P+   + S  R
Sbjct: 2364 KMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRS--R 2421

Query: 989  SQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTISPPPAP 1048
               ++  S+ +G  + +AP+  +   + A     G     HK    +P P     P PA 
Sbjct: 2422 GYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAA 2481

Query: 1049 APAAAPLPCGPTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPAS 1108
             PA  PL                                   L      P + S     S
Sbjct: 2482 LPAQQPLE---------------------------------PLAQKCQPPRKKS--HRVS 2506

Query: 1109 AFDRPARTRGRPA----DSPATWGSHYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPR 1164
              +RP  +RG P+      PA      GSK   R PG P  ++   P   +       P 
Sbjct: 2507 GKERPNHSRGDPSHVTQPPPA-----QGSKEVLRAPGSPHSQQLHPPSPTEHEVDVKTPA 2561

Query: 1165 EVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEY 1224
               R   + E EL   P  +EK +  +   +   D            R   RG+    E 
Sbjct: 2562 SKPRPDQAREDELH--PKQAEKREGRRWRREPTVDSPSHSEGKSNKKRGKLRGRRLREES 2619

Query: 1225 HV-LSPKAVPKGNGTVSCP----------HCRPIR-TQDAGG------AVTGDPLGPPPA 1266
             + +S   +  G G+   P          HC  +    +A G      A  G  +    A
Sbjct: 2620 ILPVSADVISDGRGSRPSPAMASYAASPSHCLSVEGGPEADGEQPPRLATLGPGVMEGAA 2679

Query: 1267 DTLQCPLC-GQVGS-PPEADG---PGSATSGA--EKATTRRKASSTP--SPKQRS----- 1312
            +T Q  LC G+ G+  P  D    PG     A  E+ T ++ AS+     P++       
Sbjct: 2680 ETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQKGASARGFWGPRETKALGVC 2739

Query: 1313 KQAGSSP---------RPPPGLWYLATAPPAP-------APPAFAYISS----VPIMPYP 1352
            K++GS P         R   G+W   T P  P       + PA +  SS    +P  P  
Sbjct: 2740 KESGSEPAEDSSRAHSRSEEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNPDT 2799

Query: 1353 PAAVYYAPAGPT--SAQPAAKWPPT 1375
               V   P GPT  ++  +AK PP+
Sbjct: 2800 QGGV-QGPEGPTPDASGSSAKDPPS 2823



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 144/647 (22%), Positives = 222/647 (34%), Gaps = 74/647 (11%)

Query: 773  EAMRME-EEEEGEEEEEEEGGGDSLEVDGVAATPGKAEATRVLPRQCPVQAE-----KSH 826
            +A  ME  E +  +  + E    SL     ++TPGK  + +  P + P+QA      ++ 
Sbjct: 54   QAQAMELPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAE 113

Query: 827  GAPLEEATEKMVSMKPPGFQASLARDGHMSGLGKAEA-APPGPGV-PPHPPGTKSAASHQ 884
            G+P +     + S +          +  +      E   P GPG   P  PG     +  
Sbjct: 114  GSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQP 173

Query: 885  SSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSPLTQTPEHR 944
            ++    E  G      + P       +   +    P          TS + P    PE++
Sbjct: 174  AA----EELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQP-GSYPEYQ 228

Query: 945  LSHISTAGTLAQPFAASVPRDGASY--PKARGSLIPRRATEPSTPRSQAQRYLSSPSGPL 1002
             S     G  + P AA     GA++  P A    IP+ +    +PR  + ++      P 
Sbjct: 229  AS-----GADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQF----PFPA 279

Query: 1003 RQRAPNFSLERTLAAEMAVPGS-EFEGHKRISEQPLPNKTISPPPA----PAPAAAPLPC 1057
               A        +A      G   F  H+   +   P + +   PA      PA +PLPC
Sbjct: 280  LHGASTKPFPADVAGHAFTNGPLVFAFHQ--PQGAWPEEAVGTGPAYPLPTQPAPSPLPC 337

Query: 1058 GPTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPL-QGSPTRPASAFDRPART 1116
               +  P  L   +    A+       S  R    DSLH+ L +  P RP SA D    T
Sbjct: 338  YQGQ--PGGLNRHSDLSGALSSPGAAHSAPR-PFSDSLHKSLTKILPERPPSAQDGLGST 394

Query: 1117 RGRPADSPATW--GSHYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSE 1174
            RG P+  P     G  Y +   +  PG P  + ++  PG   AR      ++   + +  
Sbjct: 395  RGPPSSLPQRHFPGQAYRASGVDTSPGPP--DTELAAPGPPPARLP----QLWDPTAAPY 448

Query: 1175 SELPSLPLFSEKSKTTKDSPQAARDGKR----GVGSAGWPDRVTFRGQYTGHEYHVLSPK 1230
               P  PL + +S      P     G+R          WP +V    + + H   +LS  
Sbjct: 449  PTPPGGPLAATRSMFFNGQPS---PGQRLCLPQSAPLPWP-QVLPTARPSPHGMEMLSRL 504

Query: 1231 AVPKGNGTVSCPHCRPIRTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSPPEADGPGSAT 1290
              P G          P     + GA+      P P + L      Q GSP      G   
Sbjct: 505  PFPAGG---------PEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTD 555

Query: 1291 SG--------AEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAFAY 1342
             G        A+   +     S P P+        SP P P     AT        + + 
Sbjct: 556  PGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSP-----ATNTAGSTCSSLSP 610

Query: 1343 ISSVPIMPYPPAAVYYAPAGPTS-AQPAAKWPPTASPPPARRHRHSI 1388
            +SS P  P    +    P GP++   P      T SP P+    HS+
Sbjct: 611  MSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSL 657



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 290/1277 (22%), Positives = 419/1277 (32%), Gaps = 273/1277 (21%)

Query: 224  DGPQPTALAETLPEGPSHHLLSPDGRTGGSVARATPMEFQDSSAPPAQSPQHATDRWRRE 283
            DG    +L   LP  P     +  GR        +   F D        P + +    R+
Sbjct: 1390 DGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRD 1449

Query: 284  T-TRFFCPQPKEHIWKQTKTSPKPLPS-RFIGSISPLNPQPRPTRQG-----RPLPRQGA 336
            +   F C  P +    +T  S  P PS   +  +SP+ P   P   G     +  P +  
Sbjct: 1450 SGLPFACADPPQ----KTVPSDPPYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERT 1505

Query: 337  TLAGRSSSNAPKYGRG----QLNYPLPDFSKVGPRVRFPKDESYRPPKSRSHNRKPQAPA 392
             + G + S  P  G G     +++   D  ++   V   + +  R   +R   R+     
Sbjct: 1506 VVPGAAPS-LPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKDTRGAPRE----- 1559

Query: 393  RPLIFKSPAEIVQEVLLSSGEAALAKDTPPAHPIT---RVPQEFQTPEQATELVHQLQED 449
                  + AE V  V L +G        PP+   T    VP E      A +L    +  
Sbjct: 1560 -----LAEAESVGRVELGTGTE------PPSQRRTCQATVPHE--DTFSAADLTRVGEST 1606

Query: 450  YHRLLTKYAEAENTIDQLRLGAKVNLFSDPPQPNHSIHTGMVPQGTKVLSFTIP-QPRSA 508
             HR   + A A     Q R G         P   H  H  ++P   + L    P  PR A
Sbjct: 1607 AHREGAESAVATVEAVQGRPGGTWPC----PASFHPGHAALLPCAQEDLVSGAPFSPRGA 1662

Query: 509  EWWPGPAEDPQASAASGWPSARGDLSPSSLTSMPTLGWLPENRDISEDQSSAEQTQALAS 568
             +   P +   AS  +G   A GD  P     +P     P  +  +   +     Q L+ 
Sbjct: 1663 NFHFQPVQKAGASK-TGLCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSF 1721

Query: 569  QASQFLAKVESFERLIQAGRLMPQDQVKGFQRLKAAHAALEEEYLKACREQHPAQPLAGS 628
              ++  A  +  E  +   RL+P +Q  GF         L E       + H   P   +
Sbjct: 1722 PKNKEAASSQESEDSL---RLLPCEQRGGF---------LPEP--GTADQPHRGAPAPEA 1767

Query: 629  KGTPGRFDPRRELEAEIYRLGSCLEELKEHIDQTQQEPEPPGSDSALDSTP-ALPCLHQP 687
             G+P        L  ++   G     L    D T      P   +   S   A   LH  
Sbjct: 1768 FGSPAV-----HLAPDLAFQGDGAPPL----DATWPFGASPSHAAQGHSAGRAGGHLHPT 1818

Query: 688  THLPAPSGQAPMPAIKTSCPEPATTTAAASTGPCPLHVNVEVSSGNSEVEDRPQDPLARL 747
               P   G    PA  +S   P    A     P P  V+      N+    R QDP    
Sbjct: 1819 AGRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVS------NTHPSRRSQDPALSP 1872

Query: 748  RHKELQMEQVYHGLMERYLSVKSLPEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATPGK 807
              ++LQ+     G+ +    +  L E     +          EGG  ++E   VA  P +
Sbjct: 1873 PIRQLQLPGP--GVAKSKDGILGLQELTPAAQSPPRVNPSGLEGG--TVEGGKVACGPAQ 1928

Query: 808  AEATRVLPRQCPVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGKAEAAP-- 865
                 V     P  A                     G Q  L  DGH   LG+AE     
Sbjct: 1929 GSPGGVQVTTLPAVA---------------------GHQLGLEADGHWGLLGQAEKTQGQ 1967

Query: 866  -------PGPGVPPHPPGTKSAAS-HQSSMTSLEG---------------SGISERLPQK 902
                   P  GV P   GT + AS + S  T+L G               + +S +   +
Sbjct: 1968 GTANQLQPENGVSPG--GTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAE 2025

Query: 903  PLHRGGGPHLEETWMA--SPETDSGFVGSETSRVS------PLTQTPEHRLSHISTAGTL 954
            P      P+ E   +A  +  + SG  G    R S      PL  T +   S   + G L
Sbjct: 2026 PTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGD---SPAPSVGDL 2082

Query: 955  AQPFAASVPRDGASYPKARGSLIPRRATEPSTPRSQAQRYLSS--PSGPLRQRAPNFSLE 1012
            A    A  P   A  P + G L PR   +P T  S+AQ  L    P+ P  +  P    +
Sbjct: 2083 AA--CAPSPTSAAHMPCSLGPL-PRE--DPLTSPSRAQGGLGGQLPASPSCRDPPG--PQ 2135

Query: 1013 RTLAAEMA-VPGSEFEGHKRISEQPLPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRA 1071
            + LA   A  P  E +G +  ++    +  ++PP     +    PC P E +        
Sbjct: 2136 QLLACSPAWAPLEEADGVQATTDTGAEDSPVAPP-----SLTTSPCDPKEAL-------- 2182

Query: 1072 GRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHY 1131
                A C LQ E S            PL+   + P  +    A T     D+P       
Sbjct: 2183 ----AGCLLQGEGS------------PLEDPSSWPPGSVS--AVTCTHSGDTP------- 2217

Query: 1132 GSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTK 1191
               ST R+P + R E+    PGR  A S  +   V        + L S P        T 
Sbjct: 2218 -KDSTLRIPEDSRKEKLWESPGR--ATSPPLAGAVSPSVAVRATGLSSTP--------TG 2266

Query: 1192 DSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQD 1251
            D  QA R      G  G PD      Q  G   H  +P  +P+G+ + S  +   +  ++
Sbjct: 2267 DEAQAGR------GLPG-PDP-----QSRGAPPHT-NPDRMPRGHSSYSPSNTARLGHRE 2313

Query: 1252 AGGAVTGDPLGPPPADTLQ-----CPLC--GQVG-SPPEADGPGSATSGAEKATTRRKA- 1302
             G AVT  P  PP   TLQ      P C  G++G S  E + PG+  +G   AT   +  
Sbjct: 2314 -GQAVTAVPTEPP---TLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVT 2369

Query: 1303 --------------SSTPSP---------------------------KQRSKQAGSSPRP 1321
                          SST S                            KQRS+     P  
Sbjct: 2370 CPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPAS 2429

Query: 1322 PPGLWYLATAPPAPAP-----------PAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAA 1370
                 +   AP  P             P  +   +    P+P A    +PA   + QP  
Sbjct: 2430 TENGQWKGQAPHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLE 2489

Query: 1371 KWPPTASPPPARRHRHS 1387
                   PP  + HR S
Sbjct: 2490 PLAQKCQPPRKKSHRVS 2506



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 92/359 (25%), Positives = 131/359 (36%), Gaps = 68/359 (18%)

Query: 1097 QPLQGSPTRPASAFD---RPARTRGR-PADSPATWGSHYGSKSTERLPGEPRGEEQIVPP 1152
            Q ++    +P  A D   +P   RG+ P+ +P   GS          P  P G   +  P
Sbjct: 56   QAMELPEAQPRQARDGELKPPSLRGQAPSSTPGKRGS----------PQTPPGRSPLQAP 105

Query: 1153 GRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDR 1212
             R   R+   P +   L ++S    P+L         T ++PQ        + +A  P+ 
Sbjct: 106  SRLAGRAEGSPPQRYILGIASSRTKPTLD-------ETPENPQ--------LEAAQLPEV 150

Query: 1213 VTFRGQYTGHEYHVLSPK--AVPKGN--GTVSC---PHCRPIRTQDAGGAVTGDPLGP-P 1264
             T +G  TG       P+  A P     G   C   P      T     + T  P  P P
Sbjct: 151  DTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGP 210

Query: 1265 PADTLQCPLCGQVGSPPE--ADGPGSATSGAEKATTRRKAS---STPSPKQRSKQAGSSP 1319
            P      PL  Q GS PE  A G  S    AE +          + P P  +  + G SP
Sbjct: 211  PQSRGTSPL--QPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSP 268

Query: 1320 R------PPPGLWYLATAPPAPAPPAFAYISSVPIM--------PYPPAAVYYAPAGPTS 1365
            R      P P L + A+  P PA  A    ++ P++         +P  AV   PA P  
Sbjct: 269  RGVSFQFPFPAL-HGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLP 327

Query: 1366 AQPAAKWPPTASPPPARRHRHSIQLDLGDLEELNKALSRAVQAAESVRSTTRQMRSSLS 1424
             QPA    P     P   +RHS         +L+ ALS    A  + R  +  +  SL+
Sbjct: 328  TQPAPSPLPCYQGQPGGLNRHS---------DLSGALSSPGAAHSAPRPFSDSLHKSLT 377



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 120/556 (21%), Positives = 181/556 (32%), Gaps = 82/556 (14%)

Query: 844  GFQASLARDGHMSGLGKAEAAPPG---PGVPPHPPGTKSAASHQSSMTSLEGSGISERLP 900
            G   + A+DGH    G     PPG   P   P  P    A     + T L          
Sbjct: 754  GLLLARAKDGHQRSPG-----PPGLPSPPAAPRVPADAHAGLLSHAKTFLLAGDAQAEGK 808

Query: 901  QKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAA 960
              PL  G  P L  T    P +D             L    + +L  + T       + +
Sbjct: 809  DDPLRTGFLPSLAATPFPLPASD-------------LDMEDDAKLDSLITEALNGMEYQS 855

Query: 961  SVPRDGASYPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRA---PNFSLERTLAA 1017
              P   +S+             EPS PR  +  +      PL+ +A   P       L A
Sbjct: 856  DNPEIDSSFIDVFAD------EEPSGPRGPSSGH------PLKSKAGVTPESKAPPPLPA 903

Query: 1018 EMAVPGSEFEGHKRISEQPLPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAI 1077
                P +   G +    +  P KT S   AP  A AP             L R   D   
Sbjct: 904  ATPDPQTPRPGDRGCPARGRP-KTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGG 962

Query: 1078 CELQE------EVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADS-PATWGSH 1130
                         S LR R  D L +     P RP +   +   +R  PA   P      
Sbjct: 963  AAEGSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRT---QAPGSRADPAPRVPRAAALP 1019

Query: 1131 YGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTT 1190
              ++S+ R    PR +     P +++AR  +  +E++   +  ++ L      SE  +  
Sbjct: 1020 EETRSSRRRRLPPRKD-----PRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDE 1074

Query: 1191 KDSPQAAR-DGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRT 1249
            +  P+     G+RG G       +T   +    +    + +    G+G        P   
Sbjct: 1075 QPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGA-------PANP 1127

Query: 1250 QDAGGAVTGDPLGPP---PADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTP 1306
            ++ GG+  G    P    P+ +L+     + G P  AD P  A     +  T  + S   
Sbjct: 1128 EEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEET 1187

Query: 1307 SPKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSA 1366
             P     Q    P          TA  + AP +  +  +   +  PPAA     AG   A
Sbjct: 1188 RPSLDFPQEAKEPE---------TAEES-APDSTEFTEA---LRSPPAAC----AGEMGA 1230

Query: 1367 QPAAKWPPTASPPPAR 1382
             P    P    PPP+R
Sbjct: 1231 SPGLLIP--EQPPPSR 1244



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 111/470 (23%), Positives = 148/470 (31%), Gaps = 83/470 (17%)

Query: 966  GASYPKARGSLIPRRAT-----------EPSTPRSQAQRYLSSPSGPLR-QRAPNFSLER 1013
            GA  P   G L PR+             E +TP ++  +      G  +    P     +
Sbjct: 8    GAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQ 67

Query: 1014 TLAAEMAVPGSEFEGHKRISEQPLPNKTISP--PPAPAPAAAPLP-CGPTETIPS---FL 1067
                E+  P    +     +    P K  SP  PP  +P  AP    G  E  P     L
Sbjct: 68   ARDGELKPPSLRGQ-----APSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYIL 122

Query: 1068 LTRAGRDQAICELQEEVSRL---RLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPA--- 1121
               + R +   +   E  +L   +L   D+   P  G+P RP        RT  +PA   
Sbjct: 123  GIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLP-----RTEAQPAAEE 177

Query: 1122 --------DSPATWGS-HYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLS 1172
                    + P+++ S +Y S S    P  P        P + R  S   P        S
Sbjct: 178  LGFHRCFQEPPSSFTSTNYTSPSATPRPPAPG-------PPQSRGTSPLQPGSYPEYQAS 230

Query: 1173 SESELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAV 1232
                 P     S         P       +G    G P  V+F  Q+     H  S K  
Sbjct: 231  GADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSF--QFPFPALHGASTKPF 288

Query: 1233 PKG-------NGTVSCPHCRPIRTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSPPEAD- 1284
            P         NG +     +P          TG P  P P      PL    G P   + 
Sbjct: 289  PADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTG-PAYPLPTQPAPSPLPCYQGQPGGLNR 347

Query: 1285 ---------GPGSATSGAEKATTRRKASSTPSPKQRSKQA----GSSPRPPPGLWYLATA 1331
                      PG+A S     +     S T    +R   A    GS+  PP  L      
Sbjct: 348  HSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSL------ 401

Query: 1332 PPAPAPPAFAY-ISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPPP 1380
             P    P  AY  S V   P PP     AP GP  A+    W PTA+P P
Sbjct: 402  -PQRHFPGQAYRASGVDTSPGPPDTELAAP-GPPPARLPQLWDPTAAPYP 449


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 60/220 (27%), Positives = 84/220 (38%), Gaps = 41/220 (18%)

Query: 1186 KSKTTKDSPQAARDG------KRGVGSAGWPDRVTFRGQYTGHEYHV-LSPKAVPKGNGT 1238
            K KT K+  +  + G      K  +G++G+P  + ++    G   +V  S    P  + +
Sbjct: 195  KIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGCVENVDASSYPPPPQSDS 254

Query: 1239 VSCPHCRPIRTQDAGGAVTGDPLGPPPADTLQCPLCGQVGS---------------PPEA 1283
             S P            + + D L PPPA+    P+  Q GS               PP A
Sbjct: 255  ASSP----------SPSFSEDNLPPPPAE-FSYPVDNQRGSGLAGPKRSSVVSPSHPPPA 303

Query: 1284 DGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAFAY- 1342
               GS   G +       A   P P       G  P PPP  +     PP P+PP+F   
Sbjct: 304  PPLGSPP-GPKPGFAPPPAPPPPPPPM----IGIPPPPPPVGFGSPGTPPPPSPPSFPPH 358

Query: 1343 --ISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPPP 1380
               ++ P  P PPAA Y     P  +QP    PP   PPP
Sbjct: 359  PDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPP 398



 Score = 34.3 bits (77), Expect = 0.89
 Identities = 50/182 (27%), Positives = 56/182 (30%), Gaps = 41/182 (22%)

Query: 1199 DGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTG 1258
            D +RG G AG P R +           V+SP   P      S P  +P      G A   
Sbjct: 279  DNQRGSGLAG-PKRSS-----------VVSPSHPPPAPPLGSPPGPKP------GFAPPP 320

Query: 1259 DPLGPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSS 1318
             P  PPP           +G PP     G  + G     T    S    P      A   
Sbjct: 321  APPPPPPP---------MIGIPPPPPPVGFGSPG-----TPPPPSPPSFPPHPDFAAPPP 366

Query: 1319 PRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASP 1378
            P PPP   Y    P  P PP        P  P PP      P GP            A P
Sbjct: 367  PPPPPAADY----PTLPPPPLSQPTGGAPPPPPPP-----PPPGPPPPPFTGADGQPAIP 417

Query: 1379 PP 1380
            PP
Sbjct: 418  PP 419



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 49/192 (25%), Positives = 62/192 (32%), Gaps = 31/192 (16%)

Query: 872  PHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSET 931
            P PP + SA+S   S +        + LP  P         E ++    +  SG  G + 
Sbjct: 247  PPPPQSDSASSPSPSFSE-------DNLPPPPA--------EFSYPVDNQRGSGLAGPKR 291

Query: 932  SRV-SPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATEPSTPRSQ 990
            S V SP         SH   A  L  P     P+ G + P A     P     P  P   
Sbjct: 292  SSVVSP---------SHPPPAPPLGSPPG---PKPGFAPPPAPPPPPPPMIGIPPPPPPV 339

Query: 991  AQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTISPPPAPAP 1050
                  SP  P     P+F      AA    P      +  +   PL   T   PP P P
Sbjct: 340  G---FGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPP 396

Query: 1051 AAAPLPCGPTET 1062
               P P  P  T
Sbjct: 397  PPPPGPPPPPFT 408


>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
           isoform 1 [Homo sapiens]
          Length = 1599

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 71/292 (24%), Positives = 106/292 (36%), Gaps = 45/292 (15%)

Query: 644 EIYRLGSCLEELKEHIDQTQQEPEPPGSDSALDSTPA---LPCLHQPTHLPAPSGQAPMP 700
           E YRL      L E I + +     P  +S   S+P     P       +  P+G  P  
Sbjct: 309 EPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSE 368

Query: 701 AIKT---SCPEPATTTAAASTGPCPLHVNVEVSSGNSEVEDRPQDPLARLRHKELQMEQV 757
            ++    S PE A   A  S  P P+    +     +     P   L+ +   E Q ++V
Sbjct: 369 DLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEV 428

Query: 758 YHGLMERYL---SVKSLPEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATPGKAEATR-- 812
              +    +   +  + P A    +EEE EEEEEEE        +G A   G+AE+ +  
Sbjct: 429 TASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE--------EGEAGEAGEAESEKGG 480

Query: 813 ---VLPRQCPVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGK-----AEAA 864
              + P   P+ A  S    LE A    V++  P  +  +        +G       EA 
Sbjct: 481 EELLPPESTPIPANLSQN--LEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEAN 538

Query: 865 PPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETW 916
           P  P V   PP   +           EGSG+    P +P         +ETW
Sbjct: 539 PAVPEVENQPPAGSNPGPES------EGSGV----PPRP------EEADETW 574



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 29/102 (28%), Positives = 40/102 (39%), Gaps = 10/102 (9%)

Query: 1262 GPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPS-PKQRSKQAGSSPR 1320
            GPPPA +         G P  A  PG  T+    +T +    +TPS P+Q    + + P 
Sbjct: 9    GPPPAPS--------PGLPQPAFPPGQ-TAPVVFSTPQATQMNTPSQPRQHFYPSRAQPP 59

Query: 1321 PPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAG 1362
                    + AP  P P A  Y +   +M  P    Y A  G
Sbjct: 60   SSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQG 101



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 82/342 (23%), Positives = 115/342 (33%), Gaps = 93/342 (27%)

Query: 800  GVAATPGKAEATRVLP-RQCPVQAEKSHGAPLEEATEKMVSMKPPGFQ--ASLARDGHMS 856
            G    PG+  +T V+P +Q PVQ     GAP              GF   AS    G  +
Sbjct: 101  GAYYIPGQGRSTYVVPTQQYPVQP----GAP--------------GFYPGASPTEFGTYA 142

Query: 857  GLGKAEAAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETW 916
            G     A  P  GV   P G   A    +    +      + +  +  ++GG    EE  
Sbjct: 143  G-----AYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIM 197

Query: 917  MAS--------PETDSGF---VGSETSRVSPLTQT-----------------PEHRLSHI 948
              +        P+T  G       ET +V+ + +                  PEH  S  
Sbjct: 198  SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSES 257

Query: 949  STAGTLAQPFAASVPRDGASYPKARGSLIP-------RRATEPSTP--RSQAQRYLSSPS 999
              +     P  + V   G S P      IP       + + E STP  R   + Y  SP 
Sbjct: 258  QPSSPSPTPSPSPVLEPG-SEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 316

Query: 1000 GPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTI----------------- 1042
             P     P   +E TL+    VP SEF      +  PL + T+                 
Sbjct: 317  -PTPLAEPILEVEVTLSKP--VPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPE 373

Query: 1043 -------SPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAI 1077
                   +PPPA  P+ +P+P  PT   P  LL  A    A+
Sbjct: 374  VESSPELAPPPA-CPSESPVPIAPTAQ-PEELLNGAPSPPAV 413



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 41/149 (27%), Positives = 61/149 (40%), Gaps = 28/149 (18%)

Query: 98  VDSPASSHEPLAWLPQQGRQLDMTEEEPDGTLGSLEVEEAGESSSRLGYE---------- 147
           + S   +  P A  P Q  +++  EEE +G  G     EAGE+ S  G E          
Sbjct: 437 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAG-----EAGEAESEKGGEELLPPESTPI 491

Query: 148 -AGLS--LEGHGNTSPMALGHGQARGWV--ASGEQASGDKLSEHSEVNPS---VELSPAR 199
            A LS  LE    T  +A+   + R  +   + ++A GD L    E NP+   VE  P  
Sbjct: 492 PANLSQNLEAAAATQ-VAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPA 550

Query: 200 SWSSGTVS----LDHPSDSLDSTWEGETD 224
             + G  S    +    +  D TW+ + D
Sbjct: 551 GSNPGPESEGSGVPPRPEEADETWDSKED 579


>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
           isoform 2 [Homo sapiens]
          Length = 1512

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 71/292 (24%), Positives = 106/292 (36%), Gaps = 45/292 (15%)

Query: 644 EIYRLGSCLEELKEHIDQTQQEPEPPGSDSALDSTPA---LPCLHQPTHLPAPSGQAPMP 700
           E YRL      L E I + +     P  +S   S+P     P       +  P+G  P  
Sbjct: 222 EPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSE 281

Query: 701 AIKT---SCPEPATTTAAASTGPCPLHVNVEVSSGNSEVEDRPQDPLARLRHKELQMEQV 757
            ++    S PE A   A  S  P P+    +     +     P   L+ +   E Q ++V
Sbjct: 282 DLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEV 341

Query: 758 YHGLMERYL---SVKSLPEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATPGKAEATR-- 812
              +    +   +  + P A    +EEE EEEEEEE        +G A   G+AE+ +  
Sbjct: 342 TASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE--------EGEAGEAGEAESEKGG 393

Query: 813 ---VLPRQCPVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGK-----AEAA 864
              + P   P+ A  S    LE A    V++  P  +  +        +G       EA 
Sbjct: 394 EELLPPESTPIPANLSQN--LEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEAN 451

Query: 865 PPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETW 916
           P  P V   PP   +           EGSG+    P +P         +ETW
Sbjct: 452 PAVPEVENQPPAGSNPGPES------EGSGV----PPRP------EEADETW 487



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 82/342 (23%), Positives = 115/342 (33%), Gaps = 93/342 (27%)

Query: 800  GVAATPGKAEATRVLP-RQCPVQAEKSHGAPLEEATEKMVSMKPPGFQ--ASLARDGHMS 856
            G    PG+  +T V+P +Q PVQ     GAP              GF   AS    G  +
Sbjct: 14   GAYYIPGQGRSTYVVPTQQYPVQP----GAP--------------GFYPGASPTEFGTYA 55

Query: 857  GLGKAEAAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETW 916
            G     A  P  GV   P G   A    +    +      + +  +  ++GG    EE  
Sbjct: 56   G-----AYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIM 110

Query: 917  MAS--------PETDSGF---VGSETSRVSPLTQT-----------------PEHRLSHI 948
              +        P+T  G       ET +V+ + +                  PEH  S  
Sbjct: 111  SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSES 170

Query: 949  STAGTLAQPFAASVPRDGASYPKARGSLIP-------RRATEPSTP--RSQAQRYLSSPS 999
              +     P  + V   G S P      IP       + + E STP  R   + Y  SP 
Sbjct: 171  QPSSPSPTPSPSPVLEPG-SEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 229

Query: 1000 GPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTI----------------- 1042
             P     P   +E TL+    VP SEF      +  PL + T+                 
Sbjct: 230  -PTPLAEPILEVEVTLSKP--VPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPE 286

Query: 1043 -------SPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAI 1077
                   +PPPA  P+ +P+P  PT   P  LL  A    A+
Sbjct: 287  VESSPELAPPPA-CPSESPVPIAPTAQ-PEELLNGAPSPPAV 326



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 41/149 (27%), Positives = 61/149 (40%), Gaps = 28/149 (18%)

Query: 98  VDSPASSHEPLAWLPQQGRQLDMTEEEPDGTLGSLEVEEAGESSSRLGYE---------- 147
           + S   +  P A  P Q  +++  EEE +G  G     EAGE+ S  G E          
Sbjct: 350 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAG-----EAGEAESEKGGEELLPPESTPI 404

Query: 148 -AGLS--LEGHGNTSPMALGHGQARGWV--ASGEQASGDKLSEHSEVNPS---VELSPAR 199
            A LS  LE    T  +A+   + R  +   + ++A GD L    E NP+   VE  P  
Sbjct: 405 PANLSQNLEAAAATQ-VAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPA 463

Query: 200 SWSSGTVS----LDHPSDSLDSTWEGETD 224
             + G  S    +    +  D TW+ + D
Sbjct: 464 GSNPGPESEGSGVPPRPEEADETWDSKED 492


>gi|38201625 eukaryotic translation initiation factor 4 gamma, 1
           isoform 3 [Homo sapiens]
          Length = 1435

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 71/292 (24%), Positives = 106/292 (36%), Gaps = 45/292 (15%)

Query: 644 EIYRLGSCLEELKEHIDQTQQEPEPPGSDSALDSTPA---LPCLHQPTHLPAPSGQAPMP 700
           E YRL      L E I + +     P  +S   S+P     P       +  P+G  P  
Sbjct: 145 EPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSE 204

Query: 701 AIKT---SCPEPATTTAAASTGPCPLHVNVEVSSGNSEVEDRPQDPLARLRHKELQMEQV 757
            ++    S PE A   A  S  P P+    +     +     P   L+ +   E Q ++V
Sbjct: 205 DLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEV 264

Query: 758 YHGLMERYL---SVKSLPEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATPGKAEATR-- 812
              +    +   +  + P A    +EEE EEEEEEE        +G A   G+AE+ +  
Sbjct: 265 TASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE--------EGEAGEAGEAESEKGG 316

Query: 813 ---VLPRQCPVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGK-----AEAA 864
              + P   P+ A  S    LE A    V++  P  +  +        +G       EA 
Sbjct: 317 EELLPPESTPIPANLSQN--LEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEAN 374

Query: 865 PPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETW 916
           P  P V   PP   +           EGSG+    P +P         +ETW
Sbjct: 375 PAVPEVENQPPAGSNPGPES------EGSGV----PPRP------EEADETW 410



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 41/149 (27%), Positives = 61/149 (40%), Gaps = 28/149 (18%)

Query: 98  VDSPASSHEPLAWLPQQGRQLDMTEEEPDGTLGSLEVEEAGESSSRLGYE---------- 147
           + S   +  P A  P Q  +++  EEE +G  G     EAGE+ S  G E          
Sbjct: 273 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAG-----EAGEAESEKGGEELLPPESTPI 327

Query: 148 -AGLS--LEGHGNTSPMALGHGQARGWV--ASGEQASGDKLSEHSEVNPS---VELSPAR 199
            A LS  LE    T  +A+   + R  +   + ++A GD L    E NP+   VE  P  
Sbjct: 328 PANLSQNLEAAAATQ-VAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPA 386

Query: 200 SWSSGTVS----LDHPSDSLDSTWEGETD 224
             + G  S    +    +  D TW+ + D
Sbjct: 387 GSNPGPESEGSGVPPRPEEADETWDSKED 415



 Score = 31.2 bits (69), Expect = 7.5
 Identities = 46/170 (27%), Positives = 61/170 (35%), Gaps = 39/170 (22%)

Query: 941  PEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIP-------RRATEPSTP--RSQA 991
            PEH  S    +     P  + V   G S P      IP       + + E STP  R   
Sbjct: 86   PEHSPSESQPSSPSPTPSPSPVLEPG-SEPNLAVLSIPGDTMTTIQMSVEESTPISRETG 144

Query: 992  QRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTI--------- 1042
            + Y  SP  P     P   +E TL+    VP SEF      +  PL + T+         
Sbjct: 145  EPYRLSPE-PTPLAEPILEVEVTLSKP--VPESEFSSSPLQAPTPLASHTVEIHEPNGMV 201

Query: 1043 ---------------SPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAI 1077
                           +PPPA  P+ +P+P  PT   P  LL  A    A+
Sbjct: 202  PSEDLEPEVESSPELAPPPA-CPSESPVPIAPTAQ-PEELLNGAPSPPAV 249


>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
           isoform 1 [Homo sapiens]
          Length = 1599

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 71/292 (24%), Positives = 106/292 (36%), Gaps = 45/292 (15%)

Query: 644 EIYRLGSCLEELKEHIDQTQQEPEPPGSDSALDSTPA---LPCLHQPTHLPAPSGQAPMP 700
           E YRL      L E I + +     P  +S   S+P     P       +  P+G  P  
Sbjct: 309 EPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSE 368

Query: 701 AIKT---SCPEPATTTAAASTGPCPLHVNVEVSSGNSEVEDRPQDPLARLRHKELQMEQV 757
            ++    S PE A   A  S  P P+    +     +     P   L+ +   E Q ++V
Sbjct: 369 DLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEV 428

Query: 758 YHGLMERYL---SVKSLPEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATPGKAEATR-- 812
              +    +   +  + P A    +EEE EEEEEEE        +G A   G+AE+ +  
Sbjct: 429 TASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE--------EGEAGEAGEAESEKGG 480

Query: 813 ---VLPRQCPVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGK-----AEAA 864
              + P   P+ A  S    LE A    V++  P  +  +        +G       EA 
Sbjct: 481 EELLPPESTPIPANLSQN--LEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEAN 538

Query: 865 PPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETW 916
           P  P V   PP   +           EGSG+    P +P         +ETW
Sbjct: 539 PAVPEVENQPPAGSNPGPES------EGSGV----PPRP------EEADETW 574



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 29/102 (28%), Positives = 40/102 (39%), Gaps = 10/102 (9%)

Query: 1262 GPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPS-PKQRSKQAGSSPR 1320
            GPPPA +         G P  A  PG  T+    +T +    +TPS P+Q    + + P 
Sbjct: 9    GPPPAPS--------PGLPQPAFPPGQ-TAPVVFSTPQATQMNTPSQPRQHFYPSRAQPP 59

Query: 1321 PPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAG 1362
                    + AP  P P A  Y +   +M  P    Y A  G
Sbjct: 60   SSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQG 101



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 82/342 (23%), Positives = 115/342 (33%), Gaps = 93/342 (27%)

Query: 800  GVAATPGKAEATRVLP-RQCPVQAEKSHGAPLEEATEKMVSMKPPGFQ--ASLARDGHMS 856
            G    PG+  +T V+P +Q PVQ     GAP              GF   AS    G  +
Sbjct: 101  GAYYIPGQGRSTYVVPTQQYPVQP----GAP--------------GFYPGASPTEFGTYA 142

Query: 857  GLGKAEAAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETW 916
            G     A  P  GV   P G   A    +    +      + +  +  ++GG    EE  
Sbjct: 143  G-----AYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIM 197

Query: 917  MAS--------PETDSGF---VGSETSRVSPLTQT-----------------PEHRLSHI 948
              +        P+T  G       ET +V+ + +                  PEH  S  
Sbjct: 198  SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSES 257

Query: 949  STAGTLAQPFAASVPRDGASYPKARGSLIP-------RRATEPSTP--RSQAQRYLSSPS 999
              +     P  + V   G S P      IP       + + E STP  R   + Y  SP 
Sbjct: 258  QPSSPSPTPSPSPVLEPG-SEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 316

Query: 1000 GPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTI----------------- 1042
             P     P   +E TL+    VP SEF      +  PL + T+                 
Sbjct: 317  -PTPLAEPILEVEVTLSKP--VPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPE 373

Query: 1043 -------SPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAI 1077
                   +PPPA  P+ +P+P  PT   P  LL  A    A+
Sbjct: 374  VESSPELAPPPA-CPSESPVPIAPTAQ-PEELLNGAPSPPAV 413



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 41/149 (27%), Positives = 61/149 (40%), Gaps = 28/149 (18%)

Query: 98  VDSPASSHEPLAWLPQQGRQLDMTEEEPDGTLGSLEVEEAGESSSRLGYE---------- 147
           + S   +  P A  P Q  +++  EEE +G  G     EAGE+ S  G E          
Sbjct: 437 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAG-----EAGEAESEKGGEELLPPESTPI 491

Query: 148 -AGLS--LEGHGNTSPMALGHGQARGWV--ASGEQASGDKLSEHSEVNPS---VELSPAR 199
            A LS  LE    T  +A+   + R  +   + ++A GD L    E NP+   VE  P  
Sbjct: 492 PANLSQNLEAAAATQ-VAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPA 550

Query: 200 SWSSGTVS----LDHPSDSLDSTWEGETD 224
             + G  S    +    +  D TW+ + D
Sbjct: 551 GSNPGPESEGSGVPPRPEEADETWDSKED 579


>gi|38201619 eukaryotic translation initiation factor 4 gamma, 1
           isoform 4 [Homo sapiens]
          Length = 1403

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 71/292 (24%), Positives = 106/292 (36%), Gaps = 45/292 (15%)

Query: 644 EIYRLGSCLEELKEHIDQTQQEPEPPGSDSALDSTPA---LPCLHQPTHLPAPSGQAPMP 700
           E YRL      L E I + +     P  +S   S+P     P       +  P+G  P  
Sbjct: 113 EPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSE 172

Query: 701 AIKT---SCPEPATTTAAASTGPCPLHVNVEVSSGNSEVEDRPQDPLARLRHKELQMEQV 757
            ++    S PE A   A  S  P P+    +     +     P   L+ +   E Q ++V
Sbjct: 173 DLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEV 232

Query: 758 YHGLMERYL---SVKSLPEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATPGKAEATR-- 812
              +    +   +  + P A    +EEE EEEEEEE        +G A   G+AE+ +  
Sbjct: 233 TASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE--------EGEAGEAGEAESEKGG 284

Query: 813 ---VLPRQCPVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGK-----AEAA 864
              + P   P+ A  S    LE A    V++  P  +  +        +G       EA 
Sbjct: 285 EELLPPESTPIPANLSQN--LEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEAN 342

Query: 865 PPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETW 916
           P  P V   PP   +           EGSG+    P +P         +ETW
Sbjct: 343 PAVPEVENQPPAGSNPGPES------EGSGV----PPRP------EEADETW 378



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 41/149 (27%), Positives = 61/149 (40%), Gaps = 28/149 (18%)

Query: 98  VDSPASSHEPLAWLPQQGRQLDMTEEEPDGTLGSLEVEEAGESSSRLGYE---------- 147
           + S   +  P A  P Q  +++  EEE +G  G     EAGE+ S  G E          
Sbjct: 241 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAG-----EAGEAESEKGGEELLPPESTPI 295

Query: 148 -AGLS--LEGHGNTSPMALGHGQARGWV--ASGEQASGDKLSEHSEVNPS---VELSPAR 199
            A LS  LE    T  +A+   + R  +   + ++A GD L    E NP+   VE  P  
Sbjct: 296 PANLSQNLEAAAATQ-VAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPA 354

Query: 200 SWSSGTVS----LDHPSDSLDSTWEGETD 224
             + G  S    +    +  D TW+ + D
Sbjct: 355 GSNPGPESEGSGVPPRPEEADETWDSKED 383



 Score = 31.2 bits (69), Expect = 7.5
 Identities = 46/170 (27%), Positives = 61/170 (35%), Gaps = 39/170 (22%)

Query: 941  PEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIP-------RRATEPSTP--RSQA 991
            PEH  S    +     P  + V   G S P      IP       + + E STP  R   
Sbjct: 54   PEHSPSESQPSSPSPTPSPSPVLEPG-SEPNLAVLSIPGDTMTTIQMSVEESTPISRETG 112

Query: 992  QRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTI--------- 1042
            + Y  SP  P     P   +E TL+    VP SEF      +  PL + T+         
Sbjct: 113  EPYRLSPE-PTPLAEPILEVEVTLSKP--VPESEFSSSPLQAPTPLASHTVEIHEPNGMV 169

Query: 1043 ---------------SPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAI 1077
                           +PPPA  P+ +P+P  PT   P  LL  A    A+
Sbjct: 170  PSEDLEPEVESSPELAPPPA-CPSESPVPIAPTAQ-PEELLNGAPSPPAV 217


>gi|91754185 hypothetical protein LOC254268 [Homo sapiens]
          Length = 836

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 44/163 (26%), Positives = 70/163 (42%), Gaps = 38/163 (23%)

Query: 342 SSSNAPKYGRGQLNYPLPDFSKVGPRVRFPKDESYRPP---------KSRSHNR------ 386
           +S N  KYG+GQ++Y LPDFSK+ P+V+ PK++    P          S+S ++      
Sbjct: 242 NSGNTFKYGQGQVHYQLPDFSKIAPKVKIPKNKIINKPLAIAKQASFSSKSRDKPTLVQD 301

Query: 387 --------------------KPQAPARPLIFKSPAEIVQEVLLS-SGEAALAKDTPPAHP 425
                               K   P++ +  +    I QE+L     EA+L+K +P +  
Sbjct: 302 SLETTPESNCVEKQHQEQKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQK 361

Query: 426 ITRVPQE--FQTPEQATELVHQLQEDYHRLLTKYAEAENTIDQ 466
            T       FQ   Q  ++  +L+E   +L TK  E    I Q
Sbjct: 362 GTSSSSSYIFQKISQGKQMCQKLKEQTDQLKTKVQEFSKRIKQ 404



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 34/112 (30%), Positives = 59/112 (52%), Gaps = 5/112 (4%)

Query: 561 EQTQALASQASQFLAKVESF-ERLIQAGRLMPQDQVKGFQRLKAAHAALEEEYLKACREQ 619
           +  Q L  Q  Q   KV+ F +R+ Q      QD+    ++L+     LE+ +L A +++
Sbjct: 379 QMCQKLKEQTDQLKTKVQEFSKRIKQDSPYHLQDKKLVLEKLQGHLELLEQNFL-ATKDK 437

Query: 620 HPA--QPLAGSKGT-PGRFDPRRELEAEIYRLGSCLEELKEHIDQTQQEPEP 668
           H    Q +   + T  G FDP R++E EI++L   LE++KE +D+++    P
Sbjct: 438 HLTLQQQVHKHESTIVGDFDPERKVEGEIFKLEMLLEDVKEKMDESKYTSAP 489


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapiens]
          Length = 673

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 133/567 (23%), Positives = 190/567 (33%), Gaps = 83/567 (14%)

Query: 869  GVPPHPP--GTKSAAS-----HQSSMTSLEGSGISERLPQKPLHRGGGPHLEET------ 915
            G PP     GT S AS      ++S+T ++ S +  R P     +   P    T      
Sbjct: 51   GTPPRASLKGTTSMASLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRA 110

Query: 916  -WMASPETDSGFVGSETSRVSPLTQTPEHRLSHI--STAGTLAQPFAASVPRDGASYPKA 972
              M  P T S  +    SR S LT TP      +  STA  L  P  AS+ R   + P+A
Sbjct: 111  SLMRRPSTAS--LTRSPSRAS-LTTTPSRASLSMTPSTAAALTMPSRASLTR---TPPRA 164

Query: 973  RGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRI 1032
              ++ P  A+   TP        +SP+G   + +P          +M    S      R 
Sbjct: 165  SLTMTPSTASLTRTPPR------ASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRA 218

Query: 1033 SEQPLPNK---TISPPPAPA---PAAAPLPCGPTETIPSFLLTRAGRDQAICELQEEVSR 1086
            S    P +   T SPP A     P+ A L   P    P+ +L+R     ++ ++    S 
Sbjct: 219  SPTGTPPRASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRT----SLTKMDSTASI 274

Query: 1087 LRLRLEDSLHQPLQGSPTRP-----------------ASAFDRPARTRGRPADSPATWGS 1129
             R     S   P  G+P+R                  AS     +RT     DS A+   
Sbjct: 275  TRTPSRPSTASPT-GTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISR 333

Query: 1130 HYGSKSTERLPGE--PRGEEQIVPPGRQRARSSSV--PREVLRLSLSSESELPSLPLFSE 1185
                 S  R P    P G+     P    +R+S    P       LSS +     P  + 
Sbjct: 334  TPPRASITRTPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRAS 393

Query: 1186 KSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCR 1245
             + T   +    +  +      G   R +     +        P+A P G    + P   
Sbjct: 394  PTGTPSTASLTRKPPR--ASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGT 451

Query: 1246 PIRTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRR----- 1300
            P R    G   T  P G P             GSP  A   GS +  +   T  R     
Sbjct: 452  PSRASPTGTQSTASPTGSPST-------ASPTGSPSTASPTGSPSRASLTRTPSRASLTK 504

Query: 1301 ---KASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAFAYI-SSVPIMPYPPAAV 1356
                AS T +P + S     S   P G    A A  +P+  A     S   +   P  A 
Sbjct: 505  MESTASITRTPSRASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRAS 564

Query: 1357 YYAPAGPT-----SAQPAAKWPPTASP 1378
               P+  +     S     + PP+ASP
Sbjct: 565  LTTPSRASLTRTPSTVLLTRMPPSASP 591



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 115/511 (22%), Positives = 165/511 (32%), Gaps = 69/511 (13%)

Query: 804  TPGKAEATRVLPRQCPV---QAEKSHGAPLEEATEKMVSMKPPGFQASLARD-GHMSGLG 859
            TP  A  TR  PR  P          G P   +  KM S       AS+ R     S  G
Sbjct: 169  TPSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDST------ASITRTLSRASPTG 222

Query: 860  KAEAAPPGPGVPPH----------------PPGTKSAASHQSSMTSLEGSGISERLPQKP 903
                A P  G PP                 P  + +    ++S+T ++ +    R P +P
Sbjct: 223  TPPRASP-TGSPPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRP 281

Query: 904  LHRGG-GPHLEETWMASPETDSGFVGSETSRVSPLTQTPEHRLSHI-STAGTLAQPFAAS 961
                  G     +   +P T S  +     R SP        L+ + STA     P  AS
Sbjct: 282  STASPTGTPSRASLSMTPSTAS--LMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRAS 339

Query: 962  VPRDGA-SYPKARGSLI-----PRRATEPSTPRSQAQRYLSSPSGPLRQ--RAPNFSLER 1013
            + R  + + P  + S       P RA+   +P + +   LSS + P     RA       
Sbjct: 340  ITRTPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPS 399

Query: 1014 TLAAEMAVPGSEFEGHKRISEQPLPNKTISP---PPAPAPAAAPLPCGPTETIPSFLLTR 1070
            T +     P +   G    +     + T SP   PP  +P   P    PT T      T 
Sbjct: 400  TASLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTG 459

Query: 1071 AGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPAR--------------- 1115
                Q+        S        S   P  GSP+R AS    P+R               
Sbjct: 460  T---QSTASPTGSPSTASPTGSPSTASPT-GSPSR-ASLTRTPSRASLTKMESTASITRT 514

Query: 1116 -TRGRPADSPATWGSHYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSE 1174
             +R  P  +P+T  S  GS ST    G P        P R     +     +   S +S 
Sbjct: 515  PSRASPTWTPST-ASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASL 573

Query: 1175 SELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPK 1234
            +  PS  L +    +   +   +R    G+ S+    ++      T        P+A P 
Sbjct: 574  TRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITR-----TPPRASPT 628

Query: 1235 GNGTVSCPHCRPIRTQDAGGAVTGDPLGPPP 1265
                 + P   P R    G      P G PP
Sbjct: 629  ETPPRASPTGTPPRASPTGTPPRASPTGTPP 659


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 141/630 (22%), Positives = 211/630 (33%), Gaps = 123/630 (19%)

Query: 868  PGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGFV 927
            P V   P GT S    + S+ +LE    +    +  L R    H++  +      D  FV
Sbjct: 257  PTVDGRPRGT-SGMGARVSLQALEAEAEAGAETEAMLQR----HIDRVYR-----DDTFV 306

Query: 928  GSET-SRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKAR--GSLIPRRATEP 984
            G  T +R  PLT+     +  ++     A+P + ++    +  P+A     LIP     P
Sbjct: 307  GRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAM----SISPQATYLSKLIPHAVLPP 362

Query: 985  S----------------------TPRSQAQ--RYLSSPSGPLRQRAPNFSLER------- 1013
            +                      +P S     R+ S  S   R R P+ S +        
Sbjct: 363  TVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSS 422

Query: 1014 -TLAAEMAVPGSEFEGHKRISEQPLPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRA- 1071
             T+ ++ +   S+  G +   E    + ++ PPP           G T      L  R+ 
Sbjct: 423  DTIVSDGSTLSSK-GGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSS 481

Query: 1072 ----GRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATW 1127
                GR  ++ +L+      R     SLHQ     P  P     +P R +      P T 
Sbjct: 482  GQLSGRSVSLRKLKRPPPPPRRT--HSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTT 539

Query: 1128 GSHYGSKSTERLPGEPRGEEQIVP---PGRQRARSSSVPREVLRLS-LSSESELPSLPLF 1183
            G   GS+     P  P      VP   PG  R    S  R +   S  SS+S  P+LP  
Sbjct: 540  G---GSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLP-- 594

Query: 1184 SEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPH 1243
             +       SP  A+  K        P+RVT           + SP A    + T  C  
Sbjct: 595  PKGLAGPPASPGKAQPPK--------PERVT----------SLRSPGASVSSSLTSLCSS 636

Query: 1244 CRPIRTQDAGGAVTGDPLG-----------------PPPADTLQCPLCGQVGSPPEADGP 1286
                   D  G     PLG                 PP       P    + +P    GP
Sbjct: 637  SSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGP 696

Query: 1287 GSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAFAYISSV 1346
             S T  + ++       +T +P Q S        PPP      + PP+  PP        
Sbjct: 697  VSTTDASPQSPP--TPQTTLTPLQESPVISKDQSPPP------SPPPSYHPPP------- 741

Query: 1347 PIMPYPPAAVYYAPAGPTSAQPA--AKWPPTASPPPARRHRHSIQLDLGDLEELNKALSR 1404
            P    P   V    A  T+ +P     WPP   PPPA   +    L + D     +A   
Sbjct: 742  PPTKKPEVVVEAPSASETAEEPLQDPNWPP--PPPPAPEEQ---DLSMADFPPPEEAFFS 796

Query: 1405 AVQAAESVRSTTRQMRSSLSADLRQAHSLR 1434
                  +  S + ++ SS +A    A +L+
Sbjct: 797  VASPEPAGPSGSPELVSSPAASSSSATALQ 826



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 118/554 (21%), Positives = 182/554 (32%), Gaps = 91/554 (16%)

Query: 621  PAQPLAGSKGTPGRFDPRR-ELEAEIYRLGSCLEELKEHIDQTQQEPEPPGSDSALDSTP 679
            P + LAG   +PG+  P + E    +   G+ +      +  +  +P P         TP
Sbjct: 594  PPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTP 653

Query: 680  ALPCLHQPTHLPAPSGQAPMPAIKTSCPEPATTTAAASTGPCPLHVNVEVSSGNSEVEDR 739
                   P H   P+  +P P+ K   P PA    AA   P  +   V  +  + +    
Sbjct: 654  LGDRFVIPPHPKVPAPFSPPPS-KPRSPNPAAPALAA---PAVVPGPVSTTDASPQSPPT 709

Query: 740  PQDPLARLRHKELQMEQVYHGLMERYLSVKSLPEAMRMEEEEEGEEEEEEEGGGDSLEVD 799
            PQ  L  L+   +  +             +S P +            ++ E   ++    
Sbjct: 710  PQTTLTPLQESPVISKD------------QSPPPSPPPSYHPPPPPTKKPEVVVEAPSAS 757

Query: 800  GVAATPGKAEATRVLPRQCPVQAEKSHG--APLEEATEKMVSMKPPGFQAS----LARDG 853
              A  P +       P   P + + S     P EEA   + S +P G   S     +   
Sbjct: 758  ETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAA 817

Query: 854  HMSGLGKAEAAPPG----PGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGG 909
              S     +  PPG    P  PP P    SA  H + +   E  G S         +GGG
Sbjct: 818  SSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCS---------KGGG 868

Query: 910  PHLEETWMASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASY 969
            P         P  D G         +PL      ++  + + G    P  A  P  G   
Sbjct: 869  P---------PREDVG---------APLVTPSLLQMVRLRSVGA---PGGAPTPALG--- 904

Query: 970  PKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGH 1029
                          PS P+   +R LS  + P+   AP+  L   +  + A   +  EG 
Sbjct: 905  --------------PSAPQKPLRRALSGRASPVP--APSSGLHAAVRLK-ACSLAASEGL 947

Query: 1030 KRISEQPLPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQEE-VSRLR 1088
                    P     PP +PA  A+ +    +  +    L R    +   +LQ   V+ LR
Sbjct: 948  SSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQ---LERPVSPETQADLQRNLVAELR 1004

Query: 1089 LRLEDSLHQPLQGSPTRPASAFDRPA----------RTRGRPADSPATWGSHYGSKSTER 1138
               E    Q  + SP  P     +P+            R  P  +P T G  +    T+R
Sbjct: 1005 SISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTKR 1064

Query: 1139 LPGEPRGEEQIVPP 1152
               E  G  Q+V P
Sbjct: 1065 ELAENGGVLQLVGP 1078



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 94/415 (22%), Positives = 136/415 (32%), Gaps = 83/415 (20%)

Query: 663  QQEPEPPGSDSALDSTPALPCLHQPTHLPAPSGQAPMPAIKTSCPEPATTTAAASTGPCP 722
            Q  P P  + + L  +P +     P   P PS   P P  K   PE      +AS     
Sbjct: 705  QSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKK--PEVVVEAPSAS----- 757

Query: 723  LHVNVEVSSGNSEVEDRPQDPLARLRHKELQMEQVYHGLMERYLSVKSLPEAMRMEEEEE 782
                 E +    +  + P  P      ++L M   +    E + SV S   A      E 
Sbjct: 758  -----ETAEEPLQDPNWPPPPPPAPEEQDLSMAD-FPPPEEAFFSVASPEPAGPSGSPEL 811

Query: 783  GEEEEEEEGGGDSLEV------DGVAATPGKAEATRV------LPRQCPVQAEKSHGAPL 830
                        +L++      D   A P  A A+        LP++ PV   K  G P 
Sbjct: 812  VSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPR 871

Query: 831  EEATEKMVSMKPPGFQASLARDGHMSGLGKAEAAPP---GPGVPPHPPGTKSAASHQSSM 887
            E+    +V+        SL +   +  +G    AP    GP  P  P   + A S ++S 
Sbjct: 872  EDVGAPLVT-------PSLLQMVRLRSVGAPGGAPTPALGPSAPQKP--LRRALSGRASP 922

Query: 888  TSLEGSGISERLPQK-----------PLHRGGGPHLEETWMASPETDSGFVGSETSR--- 933
                 SG+   +  K                G P  E     SP + + F+ S+ SR   
Sbjct: 923  VPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQ 982

Query: 934  ----VSPLTQT-------------PEHRLSHISTAGTLAQPFAASVPRDGA------SYP 970
                VSP TQ               E R          A P  A  P  G       SYP
Sbjct: 983  LERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYP 1042

Query: 971  KARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSE 1025
            +A     P     P T + + +R L+   G L+   P          +M +PGS+
Sbjct: 1043 RAEPLTAPPTNGLPHT-QDRTKRELAENGGVLQLVGPE--------EKMGLPGSD 1088



 Score = 39.3 bits (90), Expect = 0.028
 Identities = 132/575 (22%), Positives = 177/575 (30%), Gaps = 123/575 (21%)

Query: 853  GHMSGLGKAEAAPPGPG---VPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGG 909
            G   G G A   PP P    VP   PG           T    SG S +         G 
Sbjct: 540  GGSEGAGAAPC-PPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQ--------SGT 590

Query: 910  PHLEETWMASPETDSGFVGS-ETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGAS 968
            P L    +A P    G     +  RV+ L ++P   +S   T+   +    A   R G  
Sbjct: 591  PTLPPKGLAGPPASPGKAQPPKPERVTSL-RSPGASVSSSLTSLCSSSSDPAPSDRSGPQ 649

Query: 969  YPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPG--SEF 1026
                 G     R   P  P+  A    S P  P + R+PN +    LAA   VPG  S  
Sbjct: 650  ILTPLGD----RFVIPPHPKVPAP--FSPP--PSKPRSPNPAAP-ALAAPAVVPGPVSTT 700

Query: 1027 EGHKR-----------ISEQPLPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQ 1075
            +   +           + E P+ +K  SPPP+P P+  P P  P    P  ++      +
Sbjct: 701  DASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPP--PPTKKPEVVVEAPSASE 758

Query: 1076 AICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKS 1135
                            E+ L  P    P  PA     P       AD P    + +   S
Sbjct: 759  TA--------------EEPLQDPNWPPPPPPA-----PEEQDLSMADFPPPEEAFFSVAS 799

Query: 1136 TERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQ 1195
             E  P  P G  ++V      A SSS    +      S    P+ P  +  S       +
Sbjct: 800  PE--PAGPSGSPELVS---SPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAK 854

Query: 1196 AARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGA 1255
              +    G    G P R             V +P   P      S      +R+  A G 
Sbjct: 855  LPQKEPVGCSKGGGPPRED-----------VGAPLVTP------SLLQMVRLRSVGAPGG 897

Query: 1256 VTGDPLGPP-PADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQ 1314
                 LGP  P   L+  L G+    P      + +SG   A   +  S   S    S Q
Sbjct: 898  APTPALGPSAPQKPLRRALSGRASPVP------APSSGLHAAVRLKACSLAASEGLSSAQ 951

Query: 1315 AGSSPRPPPGLWYLATAPPAPAPPAFAYISSV--------PIMPY--------------- 1351
                P   P        P +PA  A    S          P+ P                
Sbjct: 952  PNGPPEAEP------RPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRS 1005

Query: 1352 -----PPAAVYYAPAGPTSAQPAAKWPPTASPPPA 1381
                 PP A   +P  P    P A+ P    PPPA
Sbjct: 1006 ISEQRPPQAPKKSPKAPP---PVARKPSVGVPPPA 1037



 Score = 37.4 bits (85), Expect = 0.10
 Identities = 126/547 (23%), Positives = 172/547 (31%), Gaps = 112/547 (20%)

Query: 854  HMSGLGKAEAAPPGP-GVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHL 912
            H  GL    A P GP G+PP P         Q  +     +G SE     P      P+ 
Sbjct: 508  HQRGL----AVPDGPLGLPPKPE-----RKQQPQLPRPPTTGGSEGAGAAPCP----PNP 554

Query: 913  EETWMASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKA 972
              +W+  P    G      SR  P  ++PE  LS   ++G  +Q    ++P  G + P A
Sbjct: 555  ANSWV--PGLSPG-----GSRRPP--RSPERTLS--PSSGYSSQSGTPTLPPKGLAGPPA 603

Query: 973  RGSLI----PRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEF-- 1026
                     P R T   +P +     L+S        AP+   +R+    +   G  F  
Sbjct: 604  SPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPS---DRSGPQILTPLGDRFVI 660

Query: 1027 EGHKRISE--QPLPNKTISP-PPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQEE 1083
              H ++     P P+K  SP P APA AA  +  GP  T  +   +       +  LQE 
Sbjct: 661  PPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQES 720

Query: 1084 VSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRP-----ADSPATWGSHYGSKSTER 1138
                       +    Q  P  P  ++  P     +P     A S +             
Sbjct: 721  ----------PVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWP 770

Query: 1139 LPGEPRGEEQIV-----PPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDS 1193
             P  P  EEQ +     PP  +   S + P        S   EL S P  S  S T    
Sbjct: 771  PPPPPAPEEQDLSMADFPPPEEAFFSVASPEPA---GPSGSPELVSSPAASSSSATALQ- 826

Query: 1194 PQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAG 1253
                      +   G PD                 P A P            P     A 
Sbjct: 827  ----------IQPPGSPD----------------PPPAPPA-----------PAPASSAP 849

Query: 1254 GAVTGDPLGPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSK 1313
            G V   P   P         C + G PP  D      + +     R ++   P       
Sbjct: 850  GHVAKLPQKEPVG-------CSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPA 902

Query: 1314 QAGSSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWP 1373
               S+P+ P        A P PAP      S +       A    A  G +SAQP    P
Sbjct: 903  LGPSAPQKPLRRALSGRASPVPAPS-----SGLHAAVRLKACSLAASEGLSSAQP--NGP 955

Query: 1374 PTASPPP 1380
            P A P P
Sbjct: 956  PEAEPRP 962



 Score = 32.0 bits (71), Expect = 4.4
 Identities = 85/358 (23%), Positives = 120/358 (33%), Gaps = 65/358 (18%)

Query: 228 PTALAETLPEGPSHHLLSPDGRT----GGSVARATPMEFQDSSAPPAQ------SPQHAT 277
           P++ ++T     S   +  DG T    GGS  +       +S  PP Q      SP   +
Sbjct: 409 PSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGS 468

Query: 278 DRWRRETTRFFCP-QPKEHIWKQTKTSPKPLPSRFIGSI---------SPLNPQPRPTRQ 327
                +T       Q         K    P P R   S+          PL   P+P R+
Sbjct: 469 TAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERK 528

Query: 328 GRPLPRQGATLAGRSSSNAPKYGRGQLNYPLPDFSKVGPRVRFPKDESYRPPKSRSHNRK 387
            +P   +  T  G   + A        N  +P  S  G R         RPP+S      
Sbjct: 529 QQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSR---------RPPRSPERTLS 579

Query: 388 PQAPARPLIFKSPAEIVQEVLLSSGEAALAKDTPPAHPITRVPQEFQTPEQATELVHQLQ 447
           P +          ++     L   G A      PPA P    P +   PE+ T L     
Sbjct: 580 PSS-------GYSSQSGTPTLPPKGLAG-----PPASPGKAQPPK---PERVTSLRSPGA 624

Query: 448 EDYHRLLTKYAEAENTIDQLRLGAKV-----NLFSDPPQPNHSIHTGMVPQGTKVLSFTI 502
                L +  + + +     R G ++     + F  PP P   +     P  +K      
Sbjct: 625 SVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHP--KVPAPFSPPPSK------ 676

Query: 503 PQPRSAEWWPGPAEDPQAS-AASGWPSARGDLSPSS-LTSMPTLGWLPENRDISEDQS 558
             PRS    P PA    A+ A    P +  D SP S  T   TL  L E+  IS+DQS
Sbjct: 677 --PRS----PNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQS 728


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 126/560 (22%), Positives = 180/560 (32%), Gaps = 122/560 (21%)

Query: 856  SGLGKAEAAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQ---KPLHRGGGPHL 912
            SG  K  A+P G   P +     S  +  S+ ++      +E + +   K       P  
Sbjct: 32   SGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSP-- 89

Query: 913  EETWMASPETDSGFVGSETSRV----SPLTQTPEHRLSHISTAGTLAQPFAASVPRDGAS 968
                + S +     V S+T       S  T+T E    +  + G      + SV  +G+S
Sbjct: 90   ----LKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSS 145

Query: 969  YPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEG 1028
             PK        R+T PS P  Q     S  S   +         +        P S   G
Sbjct: 146  DPKDIDQ--DNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG 203

Query: 1029 HKRI-SEQPLPNKTISPPP-APAPAAAP-LPCGPTETIPSFLLTRAGRDQAICELQEEVS 1085
              ++ +  P P+ T  PP  +P  + AP  P  PT  +P   +      QA     +   
Sbjct: 204  TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHI-----QQAPALHPQRPP 258

Query: 1086 RLRLRLEDSLHQPLQ------GSPTRPASAFDRPARTRGRPADSPATWG---SHYGSKST 1136
                    S H PLQ      G P+ P+ A   P   +G P       G    H G    
Sbjct: 259  SPHPPPHPSPHPPLQPLTGSAGQPSAPSHA-QPPLHGQGPPGPHSLQAGPLLQHPG---- 313

Query: 1137 ERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQA 1196
               P +P G    +PP   +A     P     L  S  +  P   L    S++   S Q 
Sbjct: 314  ---PPQPFG----LPP---QASQGQAP-----LGTSPAAAYPHTSLQLPASQSALQSQQP 358

Query: 1197 ARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAV 1256
                                            P+  P     ++ PH +P          
Sbjct: 359  --------------------------------PREQPLPPAPLAMPHIKP---------- 376

Query: 1257 TGDPLGPPPADTLQCPLCGQVGSPPEADGPGSATSGAE-----------KATTRRKASST 1305
                  PP     Q P       PP   GP   +  A              +T    S+ 
Sbjct: 377  ------PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH 430

Query: 1306 PSPKQ---RSKQAGSSPRPPPGLWYLATAPPAPA--PPAFAYISSVPIMPYPPAAVY-YA 1359
            P P Q   +S+   SSP  PPGL      PP PA  PP   +     + P PP A + + 
Sbjct: 431  PPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLH----QVAPQPPFAQHPFV 486

Query: 1360 PAGPTSAQPAAKWPPTASPP 1379
            P GP    P    P T++PP
Sbjct: 487  PGGPPPITPPT-CPSTSTPP 505



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 150/712 (21%), Positives = 239/712 (33%), Gaps = 116/712 (16%)

Query: 553  ISEDQSSAEQTQALASQASQFLAKVESFERLIQAGRLMPQDQVKGFQRLKAAHAALEEEY 612
            I+ED  S+ +    A+  S   +K E+ ++  +  +      +K  +R +   A+  EE 
Sbjct: 48   INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 107

Query: 613  ----LKACREQHPAQPLAGSKGTPGRFDPRRELEAEIYRLGSCLEELKEHIDQTQQE--- 665
                 K  + Q  ++P + S+G  G     R +  E    GS      + IDQ  +    
Sbjct: 108  DRTSSKKTKTQEISRPNSPSEGE-GESSDSRSVNDE----GS---SDPKDIDQDNRSTSP 159

Query: 666  --PEPPGSDSALDSTPALPCLH-QPTHLPAPSGQAPMPAIKTSCPEPATTTAAASTGPCP 722
              P P  ++S  DS+     L  QP  L AP+G  P P+       P  T    + GP P
Sbjct: 160  SIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPS-----SAPPGTPQLPTPGPTP 214

Query: 723  LHVNV--EVSSGNSEVEDRPQDPLARLRHKELQMEQVYHGLMERYLSVKSLP-------- 772
                V  + S   S+  ++PQ P A + H  +Q     H   +R  S    P        
Sbjct: 215  SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH--PQRPPSPHPPPHPSPHPPL 272

Query: 773  -----EAMRMEEEEEGEEEEEEEG--GGDSLEVDGVAATPGKAEATRVLPRQCPVQAEKS 825
                  A +       +     +G  G  SL+   +   PG  +     P   P QA + 
Sbjct: 273  QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ-----PFGLPPQASQG 327

Query: 826  HGAPL---EEATEKMVSMKPPGFQASLARDGHMSGLGKAEAAPPGPGVPPH--PPGT--- 877
              APL     A     S++ P  Q++L          + +  PP P   PH  PP T   
Sbjct: 328  Q-APLGTSPAAAYPHTSLQLPASQSAL----QSQQPPREQPLPPAPLAMPHIKPPPTTPI 382

Query: 878  -----KSAASHQSSMTSLEGSGISERLPQKP---------LHRGGGPH--------LEET 915
                   A  H   ++      ++  LP  P          H     H          + 
Sbjct: 383  PQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQP 442

Query: 916  WMASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQ-PFAASVPRDGASYPKARG 974
              +SP    G   S+     P +  P   L  ++     AQ PF    P      P    
Sbjct: 443  LPSSPAQPPGLTQSQNLPPPPASHPPT-GLHQVAPQPPFAQHPFVPGGP------PPITP 495

Query: 975  SLIPRRATEPSTPRSQAQRYLS--SPSGPLRQRAPNFSLERTLAAEMAVPGSEF-EGHKR 1031
               P  +T P+ P + AQ   S  + SG       +  L      E A+  +E  E    
Sbjct: 496  PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPP 555

Query: 1032 ISEQPLPNKTISPPPAPAPAAAPL---------PCGPTETIPSFLLTRAGRDQAICELQE 1082
                P P  T+   P+ A  +A            C  T+    + +  AG   A  + +E
Sbjct: 556  PPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDL---YFMPLAGSKLA-KKREE 611

Query: 1083 EVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLPGE 1142
             + + +   E    +  +    +         R R     + A+  +H G  S  +L G 
Sbjct: 612  AIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSG- 670

Query: 1143 PRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSP 1194
                     PG  R      P  +  +      + P+L   SE ++    SP
Sbjct: 671  ---------PGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSP 713



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 77/302 (25%), Positives = 108/302 (35%), Gaps = 51/302 (16%)

Query: 1102 SPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLPGEPRGEEQIVP---PGRQRAR 1158
            SP    S  +   R+ GR + S A+  S+     T +   +   EE   P     RQR +
Sbjct: 40   SPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREK 99

Query: 1159 SSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDS-PQAARDGK------RGVGSAGWPD 1211
             +S   E  R S             S+K+KT + S P +  +G+      R V   G  D
Sbjct: 100  VASDTEEADRTS-------------SKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSD 146

Query: 1212 RVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQ----DAGGAVTGDPLGPPPAD 1267
                          + SP+     + + S    + ++ Q     A   VT  P   PP  
Sbjct: 147  PKDIDQDNRSTSPSIPSPQ--DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG- 203

Query: 1268 TLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWY 1327
            T Q P  G   S       GS T  A +A  + +A + P P    +QA       P L  
Sbjct: 204  TPQLPTPGPTPSATAVPPQGSPT--ASQAPNQPQAPTAPVPHTHIQQA-------PALH- 253

Query: 1328 LATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPPPARRHRHS 1387
                PP+P PP           P+PP       AG  SA   A+ P     PP     HS
Sbjct: 254  -PQRPPSPHPPPHP-------SPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG---PHS 302

Query: 1388 IQ 1389
            +Q
Sbjct: 303  LQ 304



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 74/386 (19%), Positives = 125/386 (32%), Gaps = 44/386 (11%)

Query: 694  SGQAPMPAIKTSCPEPATTTAAASTGPCPLHVNVEVSSGNSEVEDRP-----QDPLARLR 748
            SG+   PA       P      +S    P   +   +   +E   +      ++  + L+
Sbjct: 32   SGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLK 91

Query: 749  HKELQMEQVYHGLMERYLSVKSLPEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATPGKA 808
              + Q E+V     E   +     +   +       E E E     S+  +G +      
Sbjct: 92   SNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDID 151

Query: 809  EATRVLPRQCPVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGKA-EAAPPG 867
            +  R      P   +    +    A ++M+  +PP  QA        +G+  A  +APPG
Sbjct: 152  QDNRSTSPSIPSPQDNESDSD-SSAQQQMLQAQPPALQAP-------TGVTPAPSSAPPG 203

Query: 868  -PGVP-PHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSG 925
             P +P P P  + +A   Q S T+ +    +   PQ P       H+++     P+    
Sbjct: 204  TPQLPTPGPTPSATAVPPQGSPTASQ----APNQPQAPTAPVPHTHIQQAPALHPQRP-- 257

Query: 926  FVGSETSRVSPLTQTPEHRLSH------ISTAGTLAQPFAASVPRDGASYPKARGSLIPR 979
                      P    P H   H        +AG  + P  A  P  G   P         
Sbjct: 258  ----------PSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGP 307

Query: 980  RATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPN 1039
                P  P+       +S        +P  +   T + ++    S  +  +   EQPLP 
Sbjct: 308  LLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT-SLQLPASQSALQSQQPPREQPLP- 365

Query: 1040 KTISPPPAPAPAAAPLPCGPTETIPS 1065
                P P   P   P P  P   +P+
Sbjct: 366  ----PAPLAMPHIKPPPTTPIPQLPA 387



 Score = 35.8 bits (81), Expect = 0.31
 Identities = 41/136 (30%), Positives = 53/136 (38%), Gaps = 19/136 (13%)

Query: 1262 GPPPADTLQC-PLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQ--RSKQAGSS 1318
            GPP   +LQ  PL    G P     P  A+ G     T   A+   +  Q   S+ A  S
Sbjct: 296  GPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQS 355

Query: 1319 PRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYP----PAAVYYAP--AGPTSAQPAAKW 1372
             +PP         P  PAP A  +I   P  P P    P A  + P  +GP+     A  
Sbjct: 356  QQPP------REQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANL 409

Query: 1373 PPTASPPPARRHRHSI 1388
            P    PPPA +   S+
Sbjct: 410  P----PPPALKPLSSL 421


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 126/560 (22%), Positives = 180/560 (32%), Gaps = 122/560 (21%)

Query: 856  SGLGKAEAAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQ---KPLHRGGGPHL 912
            SG  K  A+P G   P +     S  +  S+ ++      +E + +   K       P  
Sbjct: 586  SGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSP-- 643

Query: 913  EETWMASPETDSGFVGSETSRV----SPLTQTPEHRLSHISTAGTLAQPFAASVPRDGAS 968
                + S +     V S+T       S  T+T E    +  + G      + SV  +G+S
Sbjct: 644  ----LKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSS 699

Query: 969  YPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEG 1028
             PK        R+T PS P  Q     S  S   +         +        P S   G
Sbjct: 700  DPKDIDQ--DNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG 757

Query: 1029 HKRI-SEQPLPNKTISPPP-APAPAAAP-LPCGPTETIPSFLLTRAGRDQAICELQEEVS 1085
              ++ +  P P+ T  PP  +P  + AP  P  PT  +P   +      QA     +   
Sbjct: 758  TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHI-----QQAPALHPQRPP 812

Query: 1086 RLRLRLEDSLHQPLQ------GSPTRPASAFDRPARTRGRPADSPATWG---SHYGSKST 1136
                    S H PLQ      G P+ P+ A   P   +G P       G    H G    
Sbjct: 813  SPHPPPHPSPHPPLQPLTGSAGQPSAPSHA-QPPLHGQGPPGPHSLQAGPLLQHPG---- 867

Query: 1137 ERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQA 1196
               P +P G    +PP   +A     P     L  S  +  P   L    S++   S Q 
Sbjct: 868  ---PPQPFG----LPP---QASQGQAP-----LGTSPAAAYPHTSLQLPASQSALQSQQP 912

Query: 1197 ARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAV 1256
                                            P+  P     ++ PH +P          
Sbjct: 913  --------------------------------PREQPLPPAPLAMPHIKP---------- 930

Query: 1257 TGDPLGPPPADTLQCPLCGQVGSPPEADGPGSATSGAE-----------KATTRRKASST 1305
                  PP     Q P       PP   GP   +  A              +T    S+ 
Sbjct: 931  ------PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH 984

Query: 1306 PSPKQ---RSKQAGSSPRPPPGLWYLATAPPAPA--PPAFAYISSVPIMPYPPAAVY-YA 1359
            P P Q   +S+   SSP  PPGL      PP PA  PP   +     + P PP A + + 
Sbjct: 985  PPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLH----QVAPQPPFAQHPFV 1040

Query: 1360 PAGPTSAQPAAKWPPTASPP 1379
            P GP    P    P T++PP
Sbjct: 1041 PGGPPPITPPT-CPSTSTPP 1059



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 150/712 (21%), Positives = 239/712 (33%), Gaps = 116/712 (16%)

Query: 553  ISEDQSSAEQTQALASQASQFLAKVESFERLIQAGRLMPQDQVKGFQRLKAAHAALEEEY 612
            I+ED  S+ +    A+  S   +K E+ ++  +  +      +K  +R +   A+  EE 
Sbjct: 602  INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 661

Query: 613  ----LKACREQHPAQPLAGSKGTPGRFDPRRELEAEIYRLGSCLEELKEHIDQTQQE--- 665
                 K  + Q  ++P + S+G  G     R +  E    GS      + IDQ  +    
Sbjct: 662  DRTSSKKTKTQEISRPNSPSEGE-GESSDSRSVNDE----GS---SDPKDIDQDNRSTSP 713

Query: 666  --PEPPGSDSALDSTPALPCLH-QPTHLPAPSGQAPMPAIKTSCPEPATTTAAASTGPCP 722
              P P  ++S  DS+     L  QP  L AP+G  P P+       P  T    + GP P
Sbjct: 714  SIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPS-----SAPPGTPQLPTPGPTP 768

Query: 723  LHVNV--EVSSGNSEVEDRPQDPLARLRHKELQMEQVYHGLMERYLSVKSLP-------- 772
                V  + S   S+  ++PQ P A + H  +Q     H   +R  S    P        
Sbjct: 769  SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH--PQRPPSPHPPPHPSPHPPL 826

Query: 773  -----EAMRMEEEEEGEEEEEEEG--GGDSLEVDGVAATPGKAEATRVLPRQCPVQAEKS 825
                  A +       +     +G  G  SL+   +   PG  +     P   P QA + 
Sbjct: 827  QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ-----PFGLPPQASQG 881

Query: 826  HGAPL---EEATEKMVSMKPPGFQASLARDGHMSGLGKAEAAPPGPGVPPH--PPGT--- 877
              APL     A     S++ P  Q++L          + +  PP P   PH  PP T   
Sbjct: 882  Q-APLGTSPAAAYPHTSLQLPASQSAL----QSQQPPREQPLPPAPLAMPHIKPPPTTPI 936

Query: 878  -----KSAASHQSSMTSLEGSGISERLPQKP---------LHRGGGPH--------LEET 915
                   A  H   ++      ++  LP  P          H     H          + 
Sbjct: 937  PQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQP 996

Query: 916  WMASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQ-PFAASVPRDGASYPKARG 974
              +SP    G   S+     P +  P   L  ++     AQ PF    P      P    
Sbjct: 997  LPSSPAQPPGLTQSQNLPPPPASHPPT-GLHQVAPQPPFAQHPFVPGGP------PPITP 1049

Query: 975  SLIPRRATEPSTPRSQAQRYLS--SPSGPLRQRAPNFSLERTLAAEMAVPGSEF-EGHKR 1031
               P  +T P+ P + AQ   S  + SG       +  L      E A+  +E  E    
Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPP 1109

Query: 1032 ISEQPLPNKTISPPPAPAPAAAPL---------PCGPTETIPSFLLTRAGRDQAICELQE 1082
                P P  T+   P+ A  +A            C  T+    + +  AG   A  + +E
Sbjct: 1110 PPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDL---YFMPLAGSKLA-KKREE 1165

Query: 1083 EVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLPGE 1142
             + + +   E    +  +    +         R R     + A+  +H G  S  +L G 
Sbjct: 1166 AIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSG- 1224

Query: 1143 PRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSP 1194
                     PG  R      P  +  +      + P+L   SE ++    SP
Sbjct: 1225 ---------PGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSP 1267



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 77/302 (25%), Positives = 108/302 (35%), Gaps = 51/302 (16%)

Query: 1102 SPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLPGEPRGEEQIVP---PGRQRAR 1158
            SP    S  +   R+ GR + S A+  S+     T +   +   EE   P     RQR +
Sbjct: 594  SPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREK 653

Query: 1159 SSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDS-PQAARDGK------RGVGSAGWPD 1211
             +S   E  R S             S+K+KT + S P +  +G+      R V   G  D
Sbjct: 654  VASDTEEADRTS-------------SKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSD 700

Query: 1212 RVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQ----DAGGAVTGDPLGPPPAD 1267
                          + SP+     + + S    + ++ Q     A   VT  P   PP  
Sbjct: 701  PKDIDQDNRSTSPSIPSPQ--DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG- 757

Query: 1268 TLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWY 1327
            T Q P  G   S       GS T  A +A  + +A + P P    +QA       P L  
Sbjct: 758  TPQLPTPGPTPSATAVPPQGSPT--ASQAPNQPQAPTAPVPHTHIQQA-------PALH- 807

Query: 1328 LATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPPPARRHRHS 1387
                PP+P PP           P+PP       AG  SA   A+ P     PP     HS
Sbjct: 808  -PQRPPSPHPPPHP-------SPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG---PHS 856

Query: 1388 IQ 1389
            +Q
Sbjct: 857  LQ 858



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 74/386 (19%), Positives = 125/386 (32%), Gaps = 44/386 (11%)

Query: 694  SGQAPMPAIKTSCPEPATTTAAASTGPCPLHVNVEVSSGNSEVEDRP-----QDPLARLR 748
            SG+   PA       P      +S    P   +   +   +E   +      ++  + L+
Sbjct: 586  SGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLK 645

Query: 749  HKELQMEQVYHGLMERYLSVKSLPEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATPGKA 808
              + Q E+V     E   +     +   +       E E E     S+  +G +      
Sbjct: 646  SNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDID 705

Query: 809  EATRVLPRQCPVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGKA-EAAPPG 867
            +  R      P   +    +    A ++M+  +PP  QA        +G+  A  +APPG
Sbjct: 706  QDNRSTSPSIPSPQDNESDSD-SSAQQQMLQAQPPALQAP-------TGVTPAPSSAPPG 757

Query: 868  -PGVP-PHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSG 925
             P +P P P  + +A   Q S T+ +    +   PQ P       H+++     P+    
Sbjct: 758  TPQLPTPGPTPSATAVPPQGSPTASQ----APNQPQAPTAPVPHTHIQQAPALHPQRP-- 811

Query: 926  FVGSETSRVSPLTQTPEHRLSH------ISTAGTLAQPFAASVPRDGASYPKARGSLIPR 979
                      P    P H   H        +AG  + P  A  P  G   P         
Sbjct: 812  ----------PSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGP 861

Query: 980  RATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPN 1039
                P  P+       +S        +P  +   T + ++    S  +  +   EQPLP 
Sbjct: 862  LLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT-SLQLPASQSALQSQQPPREQPLP- 919

Query: 1040 KTISPPPAPAPAAAPLPCGPTETIPS 1065
                P P   P   P P  P   +P+
Sbjct: 920  ----PAPLAMPHIKPPPTTPIPQLPA 941



 Score = 35.8 bits (81), Expect = 0.31
 Identities = 41/136 (30%), Positives = 53/136 (38%), Gaps = 19/136 (13%)

Query: 1262 GPPPADTLQC-PLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQ--RSKQAGSS 1318
            GPP   +LQ  PL    G P     P  A+ G     T   A+   +  Q   S+ A  S
Sbjct: 850  GPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQS 909

Query: 1319 PRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYP----PAAVYYAP--AGPTSAQPAAKW 1372
             +PP         P  PAP A  +I   P  P P    P A  + P  +GP+     A  
Sbjct: 910  QQPP------REQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANL 963

Query: 1373 PPTASPPPARRHRHSI 1388
            P    PPPA +   S+
Sbjct: 964  P----PPPALKPLSSL 975


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.128    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,233,594
Number of Sequences: 37866
Number of extensions: 4769642
Number of successful extensions: 41221
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 197
Number of HSP's successfully gapped in prelim test: 1375
Number of HSP's that attempted gapping in prelim test: 27468
Number of HSP's gapped (non-prelim): 12702
length of query: 1439
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1324
effective length of database: 13,892,928
effective search space: 18394236672
effective search space used: 18394236672
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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