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Search of human proteins with 110347429
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110347429 mediator complex subunit 12 [Homo sapiens]
(2177 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110347429 mediator complex subunit 12 [Homo sapiens] 4395 0.0
gi|93277088 mediator of RNA polymerase II transcription, subunit... 2425 0.0
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 139 2e-32
gi|33286444 mastermind-like 2 [Homo sapiens] 139 3e-32
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 121 7e-27
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 121 9e-27
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 116 3e-25
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 112 5e-24
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 112 5e-24
gi|221139761 zinc finger protein 853 [Homo sapiens] 110 1e-23
gi|226246533 TOX high mobility group box family member 3 isoform... 96 3e-19
gi|226054295 TOX high mobility group box family member 3 isoform... 96 3e-19
gi|119943102 CREB binding protein isoform b [Homo sapiens] 95 9e-19
gi|119943104 CREB binding protein isoform a [Homo sapiens] 95 9e-19
gi|93141033 PAX interacting protein 1 [Homo sapiens] 93 2e-18
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens] 90 3e-17
gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens] 90 3e-17
gi|4507379 TATA box binding protein [Homo sapiens] 88 1e-16
gi|56549696 E1A binding protein p400 [Homo sapiens] 86 4e-16
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens] 86 5e-16
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 82 4e-15
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 81 1e-14
gi|50345997 E1A binding protein p300 [Homo sapiens] 80 2e-14
gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens] 80 2e-14
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 79 4e-14
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 79 4e-14
gi|62953127 polyhomeotic 1-like [Homo sapiens] 78 8e-14
gi|114431248 hypothetical protein LOC205717 [Homo sapiens] 76 4e-13
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 74 2e-12
gi|15812226 transcriptional regulating factor 1 [Homo sapiens] 74 2e-12
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 4395 bits (11398), Expect = 0.0
Identities = 2177/2177 (100%), Positives = 2177/2177 (100%)
Query: 1 MAAFGILSYEHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAK 60
MAAFGILSYEHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAK
Sbjct: 1 MAAFGILSYEHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAK 60
Query: 61 NVSFNPAKISSNFSSIIAEKLRCNTLPDTGRRKPQVNQKDNFWLVTARSQSAINTWFTDL 120
NVSFNPAKISSNFSSIIAEKLRCNTLPDTGRRKPQVNQKDNFWLVTARSQSAINTWFTDL
Sbjct: 61 NVSFNPAKISSNFSSIIAEKLRCNTLPDTGRRKPQVNQKDNFWLVTARSQSAINTWFTDL 120
Query: 121 AGTKPLTQLAKKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAISETKVKKRHV 180
AGTKPLTQLAKKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAISETKVKKRHV
Sbjct: 121 AGTKPLTQLAKKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAISETKVKKRHV 180
Query: 181 DPFMEWTQIITKYLWEQLQKMAEYYRPGPAGSGGCGSTIGPLPHDVEVAIRQWDYTEKLA 240
DPFMEWTQIITKYLWEQLQKMAEYYRPGPAGSGGCGSTIGPLPHDVEVAIRQWDYTEKLA
Sbjct: 181 DPFMEWTQIITKYLWEQLQKMAEYYRPGPAGSGGCGSTIGPLPHDVEVAIRQWDYTEKLA 240
Query: 241 MFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLRYSGEFVQSAYLSRRLAYF 300
MFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLRYSGEFVQSAYLSRRLAYF
Sbjct: 241 MFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLRYSGEFVQSAYLSRRLAYF 300
Query: 301 CTRRLALQLDGVSSHSSHVISAQSTSTLPTTPAPQPPTSSTPSTPFSDLLMCPQHRPLVF 360
CTRRLALQLDGVSSHSSHVISAQSTSTLPTTPAPQPPTSSTPSTPFSDLLMCPQHRPLVF
Sbjct: 301 CTRRLALQLDGVSSHSSHVISAQSTSTLPTTPAPQPPTSSTPSTPFSDLLMCPQHRPLVF 360
Query: 361 GLSCILQTILLCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAK 420
GLSCILQTILLCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAK
Sbjct: 361 GLSCILQTILLCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAK 420
Query: 421 LREIEQQIKERGQAVEVRWSFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSL 480
LREIEQQIKERGQAVEVRWSFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSL
Sbjct: 421 LREIEQQIKERGQAVEVRWSFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSL 480
Query: 481 CNRIFGLGPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAER 540
CNRIFGLGPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAER
Sbjct: 481 CNRIFGLGPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAER 540
Query: 541 CGESEAADEKGSIASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSESERVEFFNLVLLF 600
CGESEAADEKGSIASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSESERVEFFNLVLLF
Sbjct: 541 CGESEAADEKGSIASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSESERVEFFNLVLLF 600
Query: 601 CELIRHDVFSHNMYTCTLISRGDLAFGAPGPRPPSPFDDPADDPEHKEAEGSSSSKLEDP 660
CELIRHDVFSHNMYTCTLISRGDLAFGAPGPRPPSPFDDPADDPEHKEAEGSSSSKLEDP
Sbjct: 601 CELIRHDVFSHNMYTCTLISRGDLAFGAPGPRPPSPFDDPADDPEHKEAEGSSSSKLEDP 660
Query: 661 GLSESMDIDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKEVKPPPKEKIEG 720
GLSESMDIDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKEVKPPPKEKIEG
Sbjct: 661 GLSESMDIDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKEVKPPPKEKIEG 720
Query: 721 TLGVLYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILK 780
TLGVLYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILK
Sbjct: 721 TLGVLYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILK 780
Query: 781 VLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAFPTAEDIFAKFQHLSHYD 840
VLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAFPTAEDIFAKFQHLSHYD
Sbjct: 781 VLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAFPTAEDIFAKFQHLSHYD 840
Query: 841 QHQVTAQVSRNVLEQITSFALGMSYHLPLVQHVQFIFDLMEYSLSISGLIDFAIQLLNEL 900
QHQVTAQVSRNVLEQITSFALGMSYHLPLVQHVQFIFDLMEYSLSISGLIDFAIQLLNEL
Sbjct: 841 QHQVTAQVSRNVLEQITSFALGMSYHLPLVQHVQFIFDLMEYSLSISGLIDFAIQLLNEL 900
Query: 901 SVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMN 960
SVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMN
Sbjct: 901 SVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMN 960
Query: 961 RSDGSSAERCILAYLYDLYTSCSHLKNKFGELFSDFCSKVKNTIYCNVEPSESNMRWAPE 1020
RSDGSSAERCILAYLYDLYTSCSHLKNKFGELFSDFCSKVKNTIYCNVEPSESNMRWAPE
Sbjct: 961 RSDGSSAERCILAYLYDLYTSCSHLKNKFGELFSDFCSKVKNTIYCNVEPSESNMRWAPE 1020
Query: 1021 FMIDTLENPAAHTFTYTGLGKSLSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAE 1080
FMIDTLENPAAHTFTYTGLGKSLSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAE
Sbjct: 1021 FMIDTLENPAAHTFTYTGLGKSLSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAE 1080
Query: 1081 LTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQC 1140
LTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQC
Sbjct: 1081 LTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFVAILIARQC 1140
Query: 1141 LLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQLNPCQSDGNKPTVGIR 1200
LLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQLNPCQSDGNKPTVGIR
Sbjct: 1141 LLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQLNPCQSDGNKPTVGIR 1200
Query: 1201 SSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAELKGSGFTVTGGTEELPEEEGGGGSGG 1260
SSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAELKGSGFTVTGGTEELPEEEGGGGSGG
Sbjct: 1201 SSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAELKGSGFTVTGGTEELPEEEGGGGSGG 1260
Query: 1261 RRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKSLCEDSNDLQDPVLSSAQAQRL 1320
RRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKSLCEDSNDLQDPVLSSAQAQRL
Sbjct: 1261 RRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKSLCEDSNDLQDPVLSSAQAQRL 1320
Query: 1321 MQLICYPHRLLDNEDGENPQRQRIKRILQNLDQWTMRQSSLELQLMIKQTPNNEMNSLLE 1380
MQLICYPHRLLDNEDGENPQRQRIKRILQNLDQWTMRQSSLELQLMIKQTPNNEMNSLLE
Sbjct: 1321 MQLICYPHRLLDNEDGENPQRQRIKRILQNLDQWTMRQSSLELQLMIKQTPNNEMNSLLE 1380
Query: 1381 NIAKATIEVFQQSAETGSSSGSTASNMPSSSKTKPVLSSLERSGVWLVAPLIAKLPTSVQ 1440
NIAKATIEVFQQSAETGSSSGSTASNMPSSSKTKPVLSSLERSGVWLVAPLIAKLPTSVQ
Sbjct: 1381 NIAKATIEVFQQSAETGSSSGSTASNMPSSSKTKPVLSSLERSGVWLVAPLIAKLPTSVQ 1440
Query: 1441 GHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLL 1500
GHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLL
Sbjct: 1441 GHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLL 1500
Query: 1501 TSLYSQVHQIVNNWRDDQYLDDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAML 1560
TSLYSQVHQIVNNWRDDQYLDDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAML
Sbjct: 1501 TSLYSQVHQIVNNWRDDQYLDDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAML 1560
Query: 1561 LLEIIISGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLAKKL 1620
LLEIIISGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLAKKL
Sbjct: 1561 LLEIIISGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLAKKL 1620
Query: 1621 QKELGERQSDSLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVS 1680
QKELGERQSDSLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVS
Sbjct: 1621 QKELGERQSDSLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVS 1680
Query: 1681 TKQKISPWDLFEGLKPSAPLSWGWFGTVRVDRRVARGEEQQRLLLYHTHLRPRPRAYYLE 1740
TKQKISPWDLFEGLKPSAPLSWGWFGTVRVDRRVARGEEQQRLLLYHTHLRPRPRAYYLE
Sbjct: 1681 TKQKISPWDLFEGLKPSAPLSWGWFGTVRVDRRVARGEEQQRLLLYHTHLRPRPRAYYLE 1740
Query: 1741 PLPLPPEDEEPPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGKKRSQPATKTE 1800
PLPLPPEDEEPPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGKKRSQPATKTE
Sbjct: 1741 PLPLPPEDEEPPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGKKRSQPATKTE 1800
Query: 1801 DYGMGPGRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRP 1860
DYGMGPGRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRP
Sbjct: 1801 DYGMGPGRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRP 1860
Query: 1861 VRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQG 1920
VRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQG
Sbjct: 1861 VRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQG 1920
Query: 1921 MLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPST 1980
MLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPST
Sbjct: 1921 MLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPST 1980
Query: 1981 NPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQA 2040
NPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQA
Sbjct: 1981 NPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQA 2040
Query: 2041 GVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQ 2100
GVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQ
Sbjct: 2041 GVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQ 2100
Query: 2101 QQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQ 2160
QQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQ
Sbjct: 2101 QQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQ 2160
Query: 2161 QLSNTQPQPSTNIFGRY 2177
QLSNTQPQPSTNIFGRY
Sbjct: 2161 QLSNTQPQPSTNIFGRY 2177
>gi|93277088 mediator of RNA polymerase II transcription, subunit 12
homolog (S. cerevisiae)-like [Homo sapiens]
Length = 2145
Score = 2425 bits (6285), Expect = 0.0
Identities = 1318/2236 (58%), Positives = 1605/2236 (71%), Gaps = 157/2236 (7%)
Query: 1 MAAFGILSYEHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAK 60
MAAFG+LSYE RPLKRPRLGPPDVYPQDPKQKEDELTA+NVKQGFNNQPA +GDEHGSA+
Sbjct: 1 MAAFGLLSYEQRPLKRPRLGPPDVYPQDPKQKEDELTAVNVKQGFNNQPAFTGDEHGSAR 60
Query: 61 NVSFNPAKISSNFSSIIAEKLRCNTLPDTGRRKPQVNQKDNFWLVTARSQSAINTWFTDL 120
N+ NP+KI + FSSI+AEKL+ NT DTG++KPQVN KDN+WLVTARSQSAI++WF+DL
Sbjct: 61 NIVINPSKIGAYFSSILAEKLKLNTFQDTGKKKPQVNAKDNYWLVTARSQSAIHSWFSDL 120
Query: 121 AGTKPLTQLAKKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAISETKVKKRHV 180
AG KPL+ LAKKVPI SKKE+VF YLAKY+VP++RA WLIKMTCAYY+AISE K+KKR
Sbjct: 121 AGNKPLSILAKKVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKKRQA 180
Query: 181 -DPFMEWTQIITKYLWEQLQKMAEYYRPGPAGSGGCGSTIGPLPHDVEVAIRQWDYTEKL 239
DP +EWTQI T+YL EQL K++++Y A S G G P+P +VE A++QW+Y EKL
Sbjct: 181 PDPNLEWTQISTRYLREQLAKISDFYHM--ASSTGDGPV--PVPPEVEQAMKQWEYNEKL 236
Query: 240 AMFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLRYSGEFVQSAYLSRRLAY 299
A MFQ+GML++HE+LTW+L+ EKIRP +D+LLKLLLPL+L+YS EFVQSAYLSRRLAY
Sbjct: 237 AFHMFQEGMLEKHEYLTWILDVLEKIRPMDDDLLKLLLPLMLQYSDEFVQSAYLSRRLAY 296
Query: 300 FCTRRLALQLDG----VSSHSSHVISAQSTSTLPT-TPAPQPPTSSTPSTPFSDLLMCPQ 354
FC RRL+L L +++HS H++ + S++ +P P P S FSD L C Q
Sbjct: 297 FCARRLSLLLSDSPNLLAAHSPHMMIGPNNSSIGAPSPGPPGPGMSPVQLAFSDFLSCAQ 356
Query: 355 HRPLVFGLSCILQTILLCCPSALVWHYSLTDSR-IKTGSPLDHLPIAPSNLPMPEGNSAF 413
H PLV+GLSC+LQT+ LCCPSALVW+YS +++ GSPLD L +APS+LPMP GN+AF
Sbjct: 357 HGPLVYGLSCMLQTVTLCCPSALVWNYSTNENKSANPGSPLDLLQVAPSSLPMPGGNTAF 416
Query: 414 TQQVRAKLREIEQQIKERGQAVEVRWSFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDF 473
QQVRA++ E+EQQIK+RG+AVEVRWSFDKCQE+TAG TI RVLHTLEVLD H F+R+D
Sbjct: 417 NQQVRARIYEVEQQIKQRGRAVEVRWSFDKCQESTAGVTISRVLHTLEVLDRHCFDRTDS 476
Query: 474 SNSLDSLCNRIFGLGPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQ 533
SNS+++L ++IF +KD E++ +D+AVV+LLCEWAVSCKRSG+HRAM VAKLLEKRQ
Sbjct: 477 SNSMETLYHKIFWANQNKDNQEVAPNDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQ 536
Query: 534 AEIEAERCGESEAADEKGSIASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSESERVEF 593
AEIEAERCGESE DEK SI+S SL+ S P+FQ+VLL+FLDTQAP L+DP SE E+VEF
Sbjct: 537 AEIEAERCGESEVLDEKESISSSSLAGSSLPVFQNVLLRFLDTQAPSLSDPNSECEKVEF 596
Query: 594 FNLVLLFCELIRHDVFSHNMYTCTLISRGDLAFGAPGPRPPSPFDDPADDPEHKEAEGSS 653
NLVLLFCE IRHDVFSH+ Y CTLISRGDL+ A RP SP + AD+ K+ +
Sbjct: 597 VNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTA-STRPRSPVGENADEHYSKDHD--- 652
Query: 654 SSKLEDPGLSESMDIDPSSSVLFEDMEKPDFSLFSPTMP---CEGKGSPSPEKPDVEKEV 710
K+E +FSP MP CE + + V E
Sbjct: 653 -VKME---------------------------IFSP-MPGESCENANTSLGRRMSVNCEK 683
Query: 711 KPPPKEKIEGTLGVLYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHA 770
++ E YD RH+QYATHFPIP +ES SHECNQR ++L+GVGK+RD+ARH
Sbjct: 684 LVKREKPRELIFPSNYDLLRHLQYATHFPIPLDESSSHECNQRTILLYGVGKERDEARHQ 743
Query: 771 IKKITKDILKVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAFPTAEDIF 830
+KKITKDILK+LN+K T ET G++GQK R+N+ E FPT E +F
Sbjct: 744 LKKITKDILKILNKKSTTETGV----------------GDEGQKARKNKQETFPTLETVF 787
Query: 831 AKFQHLSHYDQHQVTAQVSRNVLEQITSFALGMSYHLPLVQHVQFIFDLMEYSLSISGLI 890
K Q LS++DQHQVT+Q+S NVLEQITSFA G SYHLPL H+Q IFDLME +L+I+GLI
Sbjct: 788 TKLQLLSYFDQHQVTSQISNNVLEQITSFASGTSYHLPLAHHIQLIFDLMEPALNINGLI 847
Query: 891 DFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEG 950
DFAIQLLNELSVVEAELLLKSS L GSYTT LC+CIVAVLR YH+CLILN DQ AQVFEG
Sbjct: 848 DFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTAQVFEG 907
Query: 951 LCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKNKFGELFSDFCSKVKNTIYCNVEP 1010
LCGVVKH +N S+ SS ERCILAYLYDLY SCSHL++KFG+LFS CSKVK TIY NV P
Sbjct: 908 LCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFGDLFSSACSKVKQTIYNNVMP 967
Query: 1011 SESNMRWAPEFMIDTLENPAAHTFTYTGLGKSLSENPANRYSFVCNALMHVCVGHHDPDR 1070
+ SN+RW P+FM+D +ENP+A + Y+ LGK LS+N ANRYSFVCN LM+VC+GH D R
Sbjct: 968 ANSNLRWDPDFMMDFIENPSARSINYSMLGKILSDNAANRYSFVCNTLMNVCMGHQDAGR 1027
Query: 1071 VNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLAT 1130
+NDIA +ELT C LS+EWLGVLKALCCSSN+ GFND+LC VDVSDLSFHDSLAT
Sbjct: 1028 INDIANFSSELTACCTVLSSEWLGVLKALCCSSNH-VWGFNDVLCTVDVSDLSFHDSLAT 1086
Query: 1131 FVAILIARQCLLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQLNPCQS 1190
F+AILIARQC LED+++ A+PSLL AAC + D+EPGAR+TCR+LLHLF+ PQ
Sbjct: 1087 FIAILIARQCFSLEDVVQHVALPSLLAAACGDADAEPGARMTCRLLLHLFRAPQACFLPQ 1146
Query: 1191 DGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAE--------LKGSGFTV 1242
KP GIRSSCDRHLLAA+ N I GAVFAVLKA+ +LGDA+ LK FT+
Sbjct: 1147 ATGKPFPGIRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGNNSVSSLKNDDFTM 1206
Query: 1243 TGGTEELPEEEGGGGSGGRRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKS--- 1299
G + ++ S + G++IS+ETA+L YA+YVLR+ICQQEWVGE CLK
Sbjct: 1207 RGLRCDGNADDIWTASQNPKSCGKSISIETANLREYARYVLRTICQQEWVGEHCLKEPER 1266
Query: 1300 LCEDSNDLQDPVLSSAQAQRLMQLICYPHRLLDNEDGENPQRQRIKRILQNLDQWTMRQS 1359
LC D + DPVLS+ QAQ+L+QLICYPH + + +G+N QRQ IKRILQNL+QWT+RQS
Sbjct: 1267 LCTDKELILDPVLSNMQAQKLLQLICYPHGIKECTEGDNLQRQHIKRILQNLEQWTLRQS 1326
Query: 1360 SLELQLMIKQTPNN-------EMNSLLENIAKATIEVFQQSAETGSSSGSTAS----NMP 1408
LELQLMIKQ + EMN+LL+NIAKATIEVFQQSA+ +SS S S N
Sbjct: 1327 WLELQLMIKQCLKDPGSGSVAEMNNLLDNIAKATIEVFQQSADLNNSSNSGMSLFNPNSI 1386
Query: 1409 SSSKT--------KPVLSSLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSS 1460
S+ T K LSS ER GVWLVAPLIA+LPTSVQG VLKAAGEELEKGQHLGSS
Sbjct: 1387 GSADTSSTRQNGIKTFLSSSERRGVWLVAPLIARLPTSVQGRVLKAAGEELEKGQHLGSS 1446
Query: 1461 SRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVHQIVNNWRDDQYL 1520
S+KERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSL +QV+QI++NWR+++Y
Sbjct: 1447 SKKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWREERYQ 1506
Query: 1521 DDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAMLLLEIIISGTVDMQSNNELFT 1580
DD K +Q+MHEAL+LRLNLVGGMFDTVQRSTQ TT+WA+LLL+II SGTVDM +NNELFT
Sbjct: 1507 DDIKARQMMHEALQLRLNLVGGMFDTVQRSTQWTTDWALLLLQIITSGTVDMHTNNELFT 1566
Query: 1581 TVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLAKKLQKELGERQSDSLEKVRQLLP 1640
TVLDML VLINGTLA+D+S+ S G EENKRAYMNL KKL+KELG+++S+S++KVRQLLP
Sbjct: 1567 TVLDMLGVLINGTLASDLSNASPGGSEENKRAYMNLVKKLKKELGDKRSESIDKVRQLLP 1626
Query: 1641 LPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGLKPSAPL 1700
LPKQT DVITCEP GSLIDTKGNKIAGFDSI KK+GLQVSTKQK+SPWDLFEG K APL
Sbjct: 1627 LPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKKQGLQVSTKQKVSPWDLFEGQKNPAPL 1686
Query: 1701 SWGWFGTVRVDRRVARGEEQQRLLLYHTHLRPRPRAYYLEPLPLPPEDEE--PPAPTLLE 1758
SW WFGTVRVDRRV + EEQ LLLYHTH P+PR+YYL+PLPLPPE+EE P +P E
Sbjct: 1687 SWAWFGTVRVDRRVIKYEEQHHLLLYHTHPMPKPRSYYLQPLPLPPEEEEEEPTSPVSQE 1746
Query: 1759 PEKKAPEPPKTDKPGAAPPSTEERKKKSTKGKKR-SQPATKTEDYGMGP-GRSGPYGVTV 1816
PE+K+ E K +T+E KK TKG+KR ++ +++ ++Y R P +
Sbjct: 1747 PERKSAELSDQGKT-----TTDEEKK--TKGRKRKTKSSSRVDEYPQSNIYRVPPNYSPI 1799
Query: 1817 PPDLLHHPNPGSITH-LNYRQGSIGLYTQNQPLPAGGPRVDP---YRPV--RLPMQKLPT 1870
++HHP + L + G + QNQ L GG R+DP + P + + +
Sbjct: 1800 SSQMMHHPQSTLWGYNLVGQPQQPGFFLQNQSLTPGGSRLDPAGSFVPTNTKQALSNMLQ 1859
Query: 1871 RPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQM 1930
R + + P ++ + + + +QQQ + + + R Q G Q
Sbjct: 1860 RRSGAMMQPPSLHAITSQQQLIQMKLLQQQQQQRLLRQAQTRPFQQGQPGDQAALFAAQA 1919
Query: 1931 TPSSSY----GLQTSQ----GYTPYVSHVGLQQHTGP-AGTMV-PPSYSSQPYQSTHPST 1980
PS GLQ +Q GYT Y + + LQQ + AG++V PSY+S+ Y + H +
Sbjct: 1920 RPSPQLPQYPGLQQAQTMPQGYTMYGTQMPLQQTSQQQAGSVVLSPSYNSRAYPAAH--S 1977
Query: 1981 NPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQA 2040
NP L++ R +QQ+PSGYV QQA Y LT +QR +HQ LQQ+P++ G+ A
Sbjct: 1978 NPVLMERLRQIQQQPSGYVQQQASPYLQPLTGSQRLNHQALQQSPLVGG-------GIDA 2030
Query: 2041 GVRST-AILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQ 2099
+ S LP Q + +Q Q +QQQ+ +L+ QQ QQ Q Q
Sbjct: 2031 VLTSAHPNLPSVPLPQDPMRPRQPQVRQQQR----------------LLQMQQPQQPQPQ 2074
Query: 2100 QQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQ 2159
Q Q QQ Q Q Q Q Q Q QP F RQGLQQTQQQQQTAALVRQLQ
Sbjct: 2075 QPPQPQQSSQSQSQTLGLQAMQPQ----------QPLFPRQGLQQTQQQQQTAALVRQLQ 2124
Query: 2160 QQLSNTQPQPSTNIFG 2175
+QLS+ QPQ +G
Sbjct: 2125 KQLSSNQPQQGVTPYG 2140
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 139 bits (351), Expect = 2e-32
Identities = 121/321 (37%), Positives = 150/321 (46%), Gaps = 53/321 (16%)
Query: 1869 PTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVH 1928
P+ +PG L G + + +Q+ + Q+ +QQ QQ Q +LGQ ++
Sbjct: 3695 PSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQ 3754
Query: 1929 QMTPSSSYGLQTSQ-------GYTPYVSHVGL-------QQHTGPAGTMVPPSYSSQPYQ 1974
Q G+QT+Q G P SH GL Q GP G + P + Q
Sbjct: 3755 QQQQQGP-GVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAV--LQ 3811
Query: 1975 STHPST-------NPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQT------- 2020
HP L+ +R L Q GH L + Q+ Q
Sbjct: 3812 QQHPGALGPQGPHRQVLMTQSRVLSSPQ--LAQQGQGLMGHRLVTAQQQQQQQQHQQQGS 3869
Query: 2021 ------LQQTPMISTMTP-MSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQ 2073
LQQ+ M + P +SAQ + S L +QQQ QQQQQ QQQQQQQ QQQQQ
Sbjct: 3870 MAGLSHLQQSLMSHSGQPKLSAQPMG----SLQQLQQQQQLQQQQQLQQQQQQQLQQQQQ 3925
Query: 2074 QQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQS 2133
QQ ++QQQQQQ L+QQQQQQ QQQQQQ QQQQQQQQQQ Q QQQQQQ Q +
Sbjct: 3926 LQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLL 3985
Query: 2134 QPQFQRQGLQQTQQQQQTAAL 2154
PQ QQQQQ AL
Sbjct: 3986 SPQ---------QQQQQQVAL 3997
Score = 105 bits (263), Expect = 4e-22
Identities = 105/323 (32%), Positives = 125/323 (38%), Gaps = 122/323 (37%)
Query: 1954 QQHTGPAGTMVPPSYSSQPYQSTHPSTNP-----------------TLVDPTRHLQQRPS 1996
QQH+G AG++ PS P S P L + QQ+
Sbjct: 3683 QQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQ 3742
Query: 1997 GYVH-------QQAPTYGHGLTSTQRF-----------SHQTLQQTPMISTMTPMSAQGV 2038
H QQ G G+ + Q SHQ L ++ ++P QG
Sbjct: 3743 QQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGL----LVQQLSPQPPQGP 3798
Query: 2039 QA--GVRSTAILPEQQ-----------------------------------------QQQ 2055
Q G A+L +Q QQQ
Sbjct: 3799 QGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQ 3858
Query: 2056 QQQQQQQQQ------------------------------QQQQQQQQQQQQYHIRQQQQQ 2085
QQQQQ QQQ QQ QQQQQ QQQ ++QQQQQ
Sbjct: 3859 QQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQ 3918
Query: 2086 QILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQT 2145
Q+ +QQQ QQQQ QQQQQQQQ QQQQQQQ QQQQQ Q Q Q Q Q QFQ+
Sbjct: 3919 QLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQ----QQQQQQQQQFQQ------ 3968
Query: 2146 QQQQQTAALVRQLQQQLSNTQPQ 2168
QQQQQ L+ Q + LS Q Q
Sbjct: 3969 QQQQQQMGLLNQSRTLLSPQQQQ 3991
Score = 66.2 bits (160), Expect = 3e-10
Identities = 90/318 (28%), Positives = 116/318 (36%), Gaps = 81/318 (25%)
Query: 1907 QGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGP-----AG 1961
+ ++ +QQ QQ Q S+V ++PS S L T H GLQ GP G
Sbjct: 3596 RNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGH-GLQPPQGPPGGQAGG 3654
Query: 1962 TMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTL 2021
+ P + P Q P N L QQ + G S S
Sbjct: 3655 LRLTPGGMALPGQPGGPFLNTAL--------------AQQQQQQHSGGAGSLAGPSGGFF 3700
Query: 2022 QQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIR- 2080
+ ++ P + +L E+Q Q QQQ+ Q Q+ QQQQQQQQQQ H+
Sbjct: 3701 PGNLALRSLGP-----------DSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLG 3749
Query: 2081 ----QQQQQQ-------------------------ILRQQQQQQQQQQQQQQQQQQQQQQ 2111
QQQQQQ +L QQ Q Q Q Q
Sbjct: 3750 QVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAV 3809
Query: 2112 QQQQH-----QQQQQQQAAPPQPQPQSQPQFQRQG----------LQQTQQQQQ-----T 2151
QQQH Q +Q Q + S PQ +QG QQ QQQQQ +
Sbjct: 3810 LQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGS 3869
Query: 2152 AALVRQLQQQLSNTQPQP 2169
A + LQQ L + QP
Sbjct: 3870 MAGLSHLQQSLMSHSGQP 3887
Score = 48.9 bits (115), Expect = 5e-05
Identities = 41/149 (27%), Positives = 70/149 (46%), Gaps = 10/149 (6%)
Query: 1992 QQRPSGYVHQ---QAPTYGHGLTST--QRFSHQTLQQTPMISTMTPMSAQGVQAGVRST- 2045
Q+R +G Q PT+ G+ + QR + L T + M + Q GV
Sbjct: 3480 QERSAGDPSQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQ-LKVLEEQIGVHRKS 3538
Query: 2046 --AILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQ 2103
A+ +Q+ ++ ++ + ++ + +QQ I Q+Q Q+ +QQ++ + +
Sbjct: 3539 RKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKI-QKQLDQVRKQQKEHTNLMAEYRN 3597
Query: 2104 QQQQQQQQQQQQHQQQQQQQAAPPQPQPQ 2132
+QQQQQQQQQQQ QQ A P P+
Sbjct: 3598 KQQQQQQQQQQQQQQHSAVLALSPSQSPR 3626
Score = 42.0 bits (97), Expect = 0.007
Identities = 95/445 (21%), Positives = 140/445 (31%), Gaps = 64/445 (14%)
Query: 1772 PGAAPPSTEERKKKSTKGKKRSQPATKTEDYGMGPGRSGPYGVTVPPDLLH--HPNPGSI 1829
PGA P R+ T+ + S P + G G G VT H GS+
Sbjct: 3815 PGALGPQGPHRQVLMTQSRVLSSPQLAQQ----GQGLMGHRLVTAQQQQQQQQHQQQGSM 3870
Query: 1830 THLNYRQGSIGLYTQNQPLPAG--GPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMG 1887
L++ Q S+ ++ L A G + +L Q+ + +
Sbjct: 3871 AGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQ 3930
Query: 1888 LEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPY 1947
L+ + + +QQQ + Q Q+ QQ QQ Q Q Q GL +Q T
Sbjct: 3931 LQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQ----QQQFQQQQQQQQMGL-LNQSRTLL 3985
Query: 1948 VSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYG 2007
QQ + P ++P Q ++P + PT L + V +
Sbjct: 3986 SPQQQQQQQVA-----LGPGMPAKPLQHF---SSPGALGPTLLLTGKEQNTVDPAVSSEA 4037
Query: 2008 HGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAIL-PEQQQQQQQQQQQQQQQQ 2066
ST + + TP P + +G ++ P+ Q Q Q Q +
Sbjct: 4038 TEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRL 4097
Query: 2067 QQQQQQQQQQYHI---------------RQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQ 2111
QQQQQ H +L Q Q Q QQ
Sbjct: 4098 PGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQ 4157
Query: 2112 QQQQHQQQQQQQAAPPQPQPQSQP----------------QFQRQGL-----------QQ 2144
+ Q PP+P P Q + Q QG+ Q
Sbjct: 4158 PMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQ 4217
Query: 2145 TQQQQQTAALVRQLQQQLSNTQPQP 2169
QQQ Q + RQLQQ + Q P
Sbjct: 4218 QQQQLQALLMQRQLQQSQAVRQTPP 4242
Score = 41.6 bits (96), Expect = 0.009
Identities = 92/389 (23%), Positives = 141/389 (36%), Gaps = 45/389 (11%)
Query: 1734 PRAYYLEP----LPLPPEDEEPPAPTLLEPEKKAPE---PPKTDKPGAAPPSTEERKKKS 1786
PRA +EP L L P+ E PPA L P+ P P A PP T +
Sbjct: 2333 PRASQVEPQSPGLGLRPQ-EPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP 2391
Query: 1787 TKG----KKRSQPATKTEDYGMGP-GRSGPYGVTVPPDLLHH---PNPGSITHLNYRQGS 1838
+ RS P+ P +S P L P+P + R S
Sbjct: 2392 PESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSP-----VTPRFQS 2446
Query: 1839 IGLYTQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYP-GVLPTTMTGVMGLEPSSYKTSV 1897
Y++ P DP+ P+ P + P + G L T G G P++
Sbjct: 2447 PDPYSRPPSRPQSR---DPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGF-PAALPAGP 2502
Query: 1898 YRQQQPAVPQGQRLRQQLQQSQG-MLGQSSVHQMTPSSSYGLQTSQGYTPYVSHV---GL 1953
+ VP GQ G +G S + T + G + + P G+
Sbjct: 2503 AGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGI 2562
Query: 1954 QQHTGPAGTMVPPSYSSQPYQST--HPSTNP------TLVDPTRHLQQRPSGYVHQQAPT 2005
H GP T+ P ++ + HPS +P + + RP + AP
Sbjct: 2563 NSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPD 2622
Query: 2006 YGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVR-STAILPEQQQQQQQQQQQQQQ 2064
S SH Q++ + S + G G +TA LP Q Q +
Sbjct: 2623 -----GSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTEL 2677
Query: 2065 QQQQQQQQQQQQYHIRQQQQQQILRQQQQ 2093
++Q+Q+Q+ ++ IRQQ Q+ LRQ+++
Sbjct: 2678 EKQRQRQRLRELL-IRQQIQRNTLRQEKE 2705
Score = 40.8 bits (94), Expect = 0.015
Identities = 30/81 (37%), Positives = 39/81 (48%), Gaps = 4/81 (4%)
Query: 2091 QQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQ 2150
+ ++++ Q++QQ Q Q QQQQQ QQQ +AP Q S P QQQ
Sbjct: 3254 EHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQL 3313
Query: 2151 TAAL--VRQ--LQQQLSNTQP 2167
+ L RQ L Q L TQP
Sbjct: 3314 SLGLAGARQPGLPQPLMPTQP 3334
Score = 39.7 bits (91), Expect = 0.033
Identities = 37/140 (26%), Positives = 57/140 (40%), Gaps = 43/140 (30%)
Query: 2032 PMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQ 2091
P AQGV I Q+Q ++ QQ Q Q + ++Q + ++ ++ + +Q
Sbjct: 3495 PTFAQGV--------INEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQ 3546
Query: 2092 ----------------------QQQQQQQQQQQQQQQQQ-------------QQQQQQQH 2116
+QQ + Q+Q Q ++QQ QQQQQQQ
Sbjct: 3547 RTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQ 3606
Query: 2117 QQQQQQQAAPPQPQPQSQPQ 2136
QQQQQQ +A P P+
Sbjct: 3607 QQQQQQHSAVLALSPSQSPR 3626
Score = 39.3 bits (90), Expect = 0.043
Identities = 43/153 (28%), Positives = 55/153 (35%), Gaps = 41/153 (26%)
Query: 2054 QQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQ-------- 2105
+ + +QQQQQQQQQQQQQQ + Q ++L + Q Q Q
Sbjct: 3594 EYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAG 3653
Query: 2106 ---------------------QQQQQQQQQQHQQQQQQQAAPP-----------QPQPQS 2133
QQQQQQH A P P S
Sbjct: 3654 GLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDS 3713
Query: 2134 QPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQ 2166
+ +RQ LQ QQ+ Q A ++Q QQQ Q
Sbjct: 3714 RLLQERQ-LQLQQQRMQLAQKLQQQQQQQQQQQ 3745
Score = 38.1 bits (87), Expect = 0.095
Identities = 94/454 (20%), Positives = 154/454 (33%), Gaps = 51/454 (11%)
Query: 1739 LEPLPLPPEDEEPPAPTLLEPEKKAPEP---PKTDKPGAAPPSTEERKKKSTKGKKRSQP 1795
+EP PL PE+ PPA EP + P PK ++ G P + T + +P
Sbjct: 3089 VEPGPLGPEERPPPAADASEPRLASVLPEVKPKVEEGGRHPSPCQ-----FTIATPKVEP 3143
Query: 1796 ATKTEDYGMG--PGRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIG--------LYTQN 1845
A G+G PG+S + D P S + + S G L T +
Sbjct: 3144 APAANSLGLGLKPGQS----MMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPS 3199
Query: 1846 QPLPAGGPRVDPYRPVRLPMQKLPTRPTYPG-VLPTTMTGVMGLEPSSYKTSVYRQQQPA 1904
GG + + LP P G L + ++ E + ++
Sbjct: 3200 PLSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKE 3259
Query: 1905 VPQGQRLRQQLQQSQGMLGQSSVHQMT----PSSSYGLQTSQGYTPYVSHVGLQQHTGPA 1960
+ + Q+L QLQ +Q Q H + P+ + L +G +P ++ Q G A
Sbjct: 3260 LQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLP-HEGSSPSLAGSQQQLSLGLA 3318
Query: 1961 GTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTST------- 2013
G P QP T P P LQQR + + GH L+
Sbjct: 3319 GARQPGL--PQPLMPTQP--------PAHALQQRLAPSM-AMVSNQGHMLSGQHGGQAGL 3367
Query: 2014 --QRFSHQTLQQTPMISTMTPMSAQGVQAGVR---STAILPEQQQQQQQQQQQQQQQQQQ 2068
Q+ S L Q PM + M + Q ++ + + P+ + + +
Sbjct: 3368 VPQQSSQPVLSQKPMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKA 3427
Query: 2069 QQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQ 2128
+ + + Q + +QQ Q+ Q Q+++A
Sbjct: 3428 KMVALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDP 3487
Query: 2129 PQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQL 2162
QP+ P QG+ Q+Q + QQ L
Sbjct: 3488 SQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLL 3521
Score = 35.4 bits (80), Expect = 0.62
Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 8/56 (14%)
Query: 1730 LRPRPRAYYLEPL---PLPPEDEEPPAPTLLEPEKKAPE-----PPKTDKPGAAPP 1777
L P P + PL PL P +E PP+P L P PE PP + P + PP
Sbjct: 503 LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPP 558
Score = 35.4 bits (80), Expect = 0.62
Identities = 28/84 (33%), Positives = 37/84 (44%)
Query: 2070 QQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQP 2129
Q + Q Q + + Q + L QQQQQ Q Q+Q QQ Q +Q Q+ Q +P Q
Sbjct: 4196 QLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQG 4255
Query: 2130 QPQSQPQFQRQGLQQTQQQQQTAA 2153
QPQ QT Q+ A
Sbjct: 4256 LLGCQPQLGGFPGPQTGPLQELGA 4279
Score = 35.0 bits (79), Expect = 0.80
Identities = 68/234 (29%), Positives = 85/234 (36%), Gaps = 44/234 (18%)
Query: 1818 PDLLHHPN------PGSITH--LNYRQGSIGLYTQNQPLPAGGPRVDPYRPVRLPMQKLP 1869
P LL P+ PGS+T L +Q + QN GP+ PV Q LP
Sbjct: 4131 PHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNT----GPQPPKPGPVLQSGQGLP 4186
Query: 1870 TRPTYP--GVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSV 1927
P G L + GV+ P S +QQQ Q +++QLQQSQ +V
Sbjct: 4187 GVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQ---LQALLMQRQLQQSQ------AV 4237
Query: 1928 HQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQ----STHPSTNPT 1983
Q P G QTS P +G Q G P + P Q P P
Sbjct: 4238 RQTPPYQEPGTQTS----PLQGLLGCQPQLGGF-----PGPQTGPLQELGAGPRPQGPPR 4288
Query: 1984 LVDPTRHLQQRP-SGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQ 2036
L P L P G VH P +S Q + Q P S+ P AQ
Sbjct: 4289 LPAPPGALSTGPVLGPVHPTPPP-----SSPQEPKRPS--QLPSPSSQLPTEAQ 4335
Score = 33.9 bits (76), Expect = 1.8
Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 11/59 (18%)
Query: 1730 LRPRPRAYYLEPLPL-----PPEDEEP------PAPTLLEPEKKAPEPPKTDKPGAAPP 1777
+ P P L PLP+ PP +E P +PT PE PP D P + PP
Sbjct: 644 MSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPP 702
Score = 33.1 bits (74), Expect = 3.1
Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 10/91 (10%)
Query: 631 PRPPSPFDDPADDPEHKEAEGSSSSKLEDPGLSESMDIDPSSSVLFEDMEKPDFSLFSPT 690
P P P + P P E S S LE+ LS + PS ++ P+ S SP
Sbjct: 493 PLSPPPEESPLSPPP----ESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPP 548
Query: 691 MPCEGKGSPSPEK-----PDVEKEVKPPPKE 716
E SP PE+ P + PPP+E
Sbjct: 549 FE-ESPLSPPPEELPTSPPPEASRLSPPPEE 578
Score = 32.3 bits (72), Expect = 5.2
Identities = 35/145 (24%), Positives = 50/145 (34%), Gaps = 7/145 (4%)
Query: 1730 LRPRPRAYYLEPLPLPPEDEEPPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKG 1789
L P+ A E +PL P EE P L P +++P P + +PP E +
Sbjct: 426 LEPQLEAPLNEEMPLLPPPEESP---LSPPPEESPTSPPPEASRLSPPPEELPASPLPEA 482
Query: 1790 KKRSQPATKTEDYGMGPGRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIGLYTQNQPLP 1849
S+P E P P ++ S L T P P
Sbjct: 483 LHLSRPL--EESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPP 540
Query: 1850 AGGPRVDPYR--PVRLPMQKLPTRP 1872
P P+ P+ P ++LPT P
Sbjct: 541 EASPLSPPFEESPLSPPPEELPTSP 565
Score = 32.3 bits (72), Expect = 5.2
Identities = 41/161 (25%), Positives = 60/161 (37%), Gaps = 25/161 (15%)
Query: 1729 HLRPRPRAYYLEPLPLPPEDEEPPAPTLLEPEKKAPEP------PKTDKPGAAP-PSTEE 1781
HL P+P E L L P+ EEP + E +P+P P++++P +P P
Sbjct: 796 HLSPQP-----EELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESH 850
Query: 1782 RKKKSTKGKKRSQPATKTEDYGMGPGRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIGL 1841
+ K +P E+ G P P +L P PG L+ G L
Sbjct: 851 LSPELEKPPLSPRPEKPPEEPGQCP---------APEELPLFPPPGE-PSLSPLLGEPAL 900
Query: 1842 YTQNQPLPAGGPRVDPYRPVRLPM---QKLPTRPTYPGVLP 1879
+P + P P P P Q +P P P + P
Sbjct: 901 SEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSP 941
Score = 32.3 bits (72), Expect = 5.2
Identities = 75/322 (23%), Positives = 103/322 (31%), Gaps = 49/322 (15%)
Query: 1870 TRPTYPGVLPTTMTGVM--GLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSV 1927
+ P VLP V G PS + ++ + P L L+ Q M+G
Sbjct: 3107 SEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLGLGLKPGQSMMGSRDT 3166
Query: 1928 HQMT-PSSSYGL---QTSQGYT--PYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTN 1981
T P SS G + S G T P + +GP G+ + + + T P
Sbjct: 3167 RMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGP 3226
Query: 1982 PTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAG 2041
D L + S V + P L ++ Q QQ +SAQ
Sbjct: 3227 AASGD---ELDKMESSLVASELPLLIEDLLEHEKKELQKKQQ---------LSAQ----- 3269
Query: 2042 VRSTAILPEQQQQQQQQQQQQQQQQQQQQQQ-------------QQQQYHI-----RQQQ 2083
+ P QQQQQQQQQ Q QQQ + RQ
Sbjct: 3270 -----LQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPG 3324
Query: 2084 QQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQ 2143
Q L Q QQ+ Q Q QA PQ SQP ++ +
Sbjct: 3325 LPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAG-LVPQQSSQPVLSQKPMG 3383
Query: 2144 QTQQQQQTAALVRQLQQQLSNT 2165
+QQQL+N+
Sbjct: 3384 TMPPSMCMKPQQLAMQQQLANS 3405
Score = 32.0 bits (71), Expect = 6.8
Identities = 34/133 (25%), Positives = 54/133 (40%), Gaps = 20/133 (15%)
Query: 633 PPSPFDDPADDPE--HKEAEGS------SSSKLEDPG--LSESMDIDPSSSVLFEDMEKP 682
PP P D P D+P+ + +G +S + ++PG E+ + + L +E P
Sbjct: 374 PPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAP 433
Query: 683 ---DFSLFSPTMPCEGKGSPSPEK-----PDVEKEVKPPPKEKIEGTLGVLYDQPRHVQY 734
+ L P P E SP PE+ P + PPP+E L R ++
Sbjct: 434 LNEEMPLLPP--PEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEE 491
Query: 735 ATHFPIPQEESCS 747
+ P P+E S
Sbjct: 492 SPLSPPPEESPLS 504
Score = 32.0 bits (71), Expect = 6.8
Identities = 38/151 (25%), Positives = 55/151 (36%), Gaps = 14/151 (9%)
Query: 1990 HLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQA-----GVRS 2044
HL +PS + Q + L Q Q + + PM + P + G+
Sbjct: 4132 HLLAQPSVSLGDQPGSMTQNLLGPQ----QPMLERPMQNNTGPQPPKPGPVLQSGQGLPG 4187
Query: 2045 TAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQ 2104
I+P Q + Q Q + Q + QQ QQQ Q +L Q+Q QQ Q +Q
Sbjct: 4188 VGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQ-----QQQLQALLMQRQLQQSQAVRQTPP 4242
Query: 2105 QQQQQQQQQQQHQQQQQQQAAPPQPQPQSQP 2135
Q+ Q Q P PQ+ P
Sbjct: 4243 YQEPGTQTSPLQGLLGCQPQLGGFPGPQTGP 4273
Score = 31.6 bits (70), Expect = 8.9
Identities = 28/115 (24%), Positives = 42/115 (36%), Gaps = 23/115 (20%)
Query: 622 GDLAFGAPGPRPP--------------SPFDDPADDPEHKEAEGSSSSKLEDPGLSESMD 667
GDL+ AP P P D P PE + GS +S+L+ +
Sbjct: 1099 GDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELK----GSPVL 1154
Query: 668 IDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKEVKPPPKEKIEGTL 722
+DP ME ++ G+GSP E+ + V P P I+ +
Sbjct: 1155 LDPEELAPVTPME-----VYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDI 1204
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 139 bits (350), Expect = 3e-32
Identities = 132/373 (35%), Positives = 168/373 (45%), Gaps = 76/373 (20%)
Query: 1849 PAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQ-QQPAVPQ 1907
P+ GP +P+ P P T +G PS + S +Q +Q A +
Sbjct: 385 PSAGPAFSMANSALSTSSPIPSVPQSQAQ-PQTGSGASRALPSWQEVSHAQQLKQIAANR 443
Query: 1908 GQRLRQQLQQSQ-----------------GMLGQSSVHQMTPSSSYGLQTSQGYTPYVSH 1950
Q R Q Q Q G GQ + PS S+G QT ++P S
Sbjct: 444 QQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKI----PSPSFGQQT---FSPQSSP 496
Query: 1951 V-GLQQHTGPAGTMVPPSYSSQPY-QSTHPSTNPTLVDPTRHLQQRPS----GYVHQQAP 2004
+ G+ +G + M Y + P Q H +QQ+P +++ P
Sbjct: 497 MPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVL---------MQQKPQDLSRSFINNPHP 547
Query: 2005 TYGHGLTSTQRFSH----QTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQ 2060
+T+ H Q QQ P + + +Q + + T QQQQQQQQQQ
Sbjct: 548 AMEPRQGNTKPLFHFNSDQANQQMPSV-----LPSQNKPSLLHYT-----QQQQQQQQQQ 597
Query: 2061 QQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQ-----QQQQQQQQQQQQQQQQQQQ 2115
QQQQQQQQQQQQQQQQ +QQQQ I QQQQQQQ QQQQQQQQQQQQQQQQQQQ
Sbjct: 598 QQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQ 657
Query: 2116 HQQQQQQ-------QAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQL------ 2162
QQQQQQ Q+ P QP +S Q++ L Q Q Q A + Q+ QQ
Sbjct: 658 QQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHS 717
Query: 2163 ---SNTQPQPSTN 2172
NT P PS N
Sbjct: 718 VVGQNTGPSPSPN 730
Score = 101 bits (251), Expect = 9e-21
Identities = 105/341 (30%), Positives = 135/341 (39%), Gaps = 53/341 (15%)
Query: 1863 LPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQ--------PAVPQGQRLRQQ 1914
LPM+K+ + Y L +G L P S + P+VPQ Q
Sbjct: 357 LPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQA---- 412
Query: 1915 LQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQ 1974
Q Q G S S+ Q Q H +QQH Q +Q
Sbjct: 413 --QPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQH-------------QQQHQ 457
Query: 1975 STHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTL-----QQTPMIST 2029
T+ S P+ P+ P G +P++G S Q + Q M +
Sbjct: 458 PTNWSALPSSAGPS----PGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANY 513
Query: 2030 MTPM--SAQGVQAGV----------RSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQY 2077
M SAQG V RS P + +Q + Q QQ
Sbjct: 514 MYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPS 573
Query: 2078 HIRQQQQQQIL-----RQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQ 2132
+ Q + +L +QQQQQQQQQQQQQQQQQQQQQQQQQQ QQQQ +A Q Q Q
Sbjct: 574 VLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQ 633
Query: 2133 SQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPSTNI 2173
S Q+Q QQ QQQQQ +Q QQQ QP+ ++
Sbjct: 634 SSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSL 674
Score = 92.0 bits (227), Expect = 6e-18
Identities = 115/419 (27%), Positives = 160/419 (38%), Gaps = 45/419 (10%)
Query: 1767 PKTDKPGAAPPSTEERKKKSTKGKKRSQPATKTEDY-GMGPGRSGPYGVTVP-PDLLHHP 1824
P+ P A P + ST S P ++ + G G R+ P V L
Sbjct: 380 PQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQI 439
Query: 1825 NPGSITHLNYRQGSIGLYTQNQP-----LPAG-GPRVDPYRPVRLPMQKLPTRPTYPGVL 1878
H +Q Q+QP LP+ GP P+ ++P + P
Sbjct: 440 AANRQQHARMQQHQ----QQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSS 495
Query: 1879 PTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGL 1938
P M GV G S + Y + QG L +QQ L +S ++ P+ +
Sbjct: 496 P--MPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPA----M 549
Query: 1939 QTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTN-PTLVDPTRHLQQRPSG 1997
+ QG T + H Q ++Q S PS N P+L+ T+ QQ+
Sbjct: 550 EPRQGNTKPLFHFNSDQ-------------ANQQMPSVLPSQNKPSLLHYTQQQQQQQQQ 596
Query: 1998 YVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGV--RSTAILPEQQQQQ 2055
QQ Q+ Q QQ S+++ Q Q+ + + +QQQQQ
Sbjct: 597 QQQQQQQQQ-----QQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQ 651
Query: 2056 QQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQ----QQQQQQQQQ 2111
QQQQQQQQQQQQQQ Q Q Q + L QQ+ QQ Q Q Q QQQ
Sbjct: 652 QQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQ 711
Query: 2112 QQQQHQQQQQQQAAPPQPQPQSQPQFQR--QGLQQTQQQQQTAALVRQLQQQLSNTQPQ 2168
+Q QH Q P P P S P QQ+ QQ + LQ+Q+ + Q
Sbjct: 712 RQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQ 770
Score = 50.8 bits (120), Expect = 1e-05
Identities = 78/325 (24%), Positives = 103/325 (31%), Gaps = 72/325 (22%)
Query: 1845 NQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSV--YRQQQ 1902
N P PA PR +P+ P VLP S K S+ Y QQQ
Sbjct: 543 NNPHPAMEPRQGNTKPL-FHFNSDQANQQMPSVLP-----------SQNKPSLLHYTQQQ 590
Query: 1903 PAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGT 1962
Q Q+ +QQ QQ Q Q Q SS Q Q +S QQ
Sbjct: 591 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQ 650
Query: 1963 MVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQ 2022
Q Q PS+ P P++ L + P L Q+ Q +Q
Sbjct: 651 QQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSP--------------LPLQQKLLLQQMQ 696
Query: 2023 QTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQ------------------ 2064
P+ + G Q QQQ+Q Q Q
Sbjct: 697 NQPI-------AGMGYQVS---------QQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSG 740
Query: 2065 -QQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQ 2123
QQ QQ +Q Q+QI+ Q+QQ QQQ ++ Q Q +H
Sbjct: 741 YMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLS----- 795
Query: 2124 AAPPQPQPQSQPQFQRQGLQQTQQQ 2148
+P P + Q + G Q Q
Sbjct: 796 ----RPPPDYKDQRRNVGNMQPTAQ 816
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 121 bits (304), Expect = 7e-27
Identities = 81/180 (45%), Positives = 106/180 (58%), Gaps = 8/180 (4%)
Query: 1990 HLQQRPSGYVHQQA--PTYGHGLTSTQRFSHQTLQQTPM-ISTMTP--MSAQGVQAGVRS 2044
HLQQ+ + +Q GL S + Q Q P+ ++ MTP ++ Q +Q ++
Sbjct: 51 HLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQ 110
Query: 2045 TAILPEQQQ---QQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQ 2101
+ P+Q Q QQQQ QQQQ Q+ ++QQ+Q H++ QQQQ +QQQQQQQQQQQQ
Sbjct: 111 QVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQ 170
Query: 2102 QQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQ 2161
QQQQQQQQQQQQQQ QQQQQQ + Q Q Q Q+Q Q QQ ++QLQQQ
Sbjct: 171 QQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQ 230
Score = 110 bits (274), Expect = 2e-23
Identities = 75/151 (49%), Positives = 89/151 (58%), Gaps = 14/151 (9%)
Query: 2020 TLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHI 2079
T QQ I +S Q +QA ++ + QQQQ Q+ ++QQ+Q Q QQQQQ
Sbjct: 100 TPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQ 159
Query: 2080 RQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQ-------QQQQHQQQQQQQAAPPQPQPQ 2132
+QQQQQQ +QQQQQQQQQQQQQQQQQQQQQQ +QQQ QQQQQQ AA
Sbjct: 160 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA------- 212
Query: 2133 SQPQFQRQGLQQTQQQQQTAALVRQLQQQLS 2163
Q FQ+Q LQ Q QQQ L Q Q +S
Sbjct: 213 QQLVFQQQLLQMQQLQQQQHLLSLQRQGLIS 243
Score = 93.2 bits (230), Expect = 2e-18
Identities = 88/261 (33%), Positives = 110/261 (42%), Gaps = 50/261 (19%)
Query: 1897 VYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSS---SYGLQTSQGYTPYVSHVGL 1953
++ QQQ A+ ++L Q QQ+ G+ S + P S + T Q TP L
Sbjct: 50 LHLQQQQALQAARQLLLQ-QQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQIL 108
Query: 1954 QQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTST 2013
QQ S Q Q+ ++ QQ Y QQ + L
Sbjct: 109 QQQV----------LSPQQLQALLQQQQAVMLQQ----QQLQEFYKKQQEQLHLQLLQQQ 154
Query: 2014 QRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQ 2073
Q+ Q QQ QQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 155 QQQQQQQQQQ---------------------------QQQQQQQQQQQQQQQQQQQQQQQ 187
Query: 2074 QQQYHIRQQQQQQILRQQQQQQQQQQQQ--QQQQQQQQQQQQQQHQQQQQQQ---AAPPQ 2128
QQQ H +Q ++Q +QQQQQQ QQ QQQ Q QQ QQQQH Q+Q + PP
Sbjct: 188 QQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPG 247
Query: 2129 PQPQSQPQFQRQGLQQTQQQQ 2149
+ GL + QQ
Sbjct: 248 QAALPVQSLPQAGLSPAEIQQ 268
Score = 88.2 bits (217), Expect = 8e-17
Identities = 62/158 (39%), Positives = 77/158 (48%), Gaps = 10/158 (6%)
Query: 2021 LQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQ----------QQQQQQQQQQQQQQQ 2070
LQQ + + Q +G++S +Q+ Q Q QQ QQ QQQ
Sbjct: 52 LQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQ 111
Query: 2071 QQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQ 2130
QQ QQQQ ++ QQQQ Q+ ++QQ+Q Q QQQQQ QQQQQQQ Q Q
Sbjct: 112 VLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQ 171
Query: 2131 PQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQ 2168
Q Q Q Q+Q QQ QQQQQ + QQQ Q Q
Sbjct: 172 QQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQ 209
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 121 bits (303), Expect = 9e-27
Identities = 79/183 (43%), Positives = 103/183 (56%), Gaps = 5/183 (2%)
Query: 1984 LVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTP--MSAQGVQAG 2041
L P +QRP + + G +S H T ++ MTP ++ Q +Q
Sbjct: 73 LKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHNTFAVPVSVAMMTPQVITPQQMQQI 132
Query: 2042 VRSTAILPEQQQ---QQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQ 2098
++ + P+Q Q QQQQ QQQQ Q+ ++QQ+Q H++ QQQQ +QQQQQQQQQ
Sbjct: 133 LQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQ 192
Query: 2099 QQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQL 2158
QQQQQQQQQQQQQQQQQ QQQQQQ + Q Q Q Q+Q Q QQ ++QL
Sbjct: 193 QQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQL 252
Query: 2159 QQQ 2161
QQQ
Sbjct: 253 QQQ 255
Score = 110 bits (274), Expect = 2e-23
Identities = 75/151 (49%), Positives = 89/151 (58%), Gaps = 14/151 (9%)
Query: 2020 TLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHI 2079
T QQ I +S Q +QA ++ + QQQQ Q+ ++QQ+Q Q QQQQQ
Sbjct: 125 TPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQ 184
Query: 2080 RQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQ-------QQQQHQQQQQQQAAPPQPQPQ 2132
+QQQQQQ +QQQQQQQQQQQQQQQQQQQQQQ +QQQ QQQQQQ AA
Sbjct: 185 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA------- 237
Query: 2133 SQPQFQRQGLQQTQQQQQTAALVRQLQQQLS 2163
Q FQ+Q LQ Q QQQ L Q Q +S
Sbjct: 238 QQLVFQQQLLQMQQLQQQQHLLSLQRQGLIS 268
Score = 92.0 bits (227), Expect = 6e-18
Identities = 56/105 (53%), Positives = 65/105 (61%), Gaps = 5/105 (4%)
Query: 2050 EQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQ--QQQQQQ 2107
+QQQQQQQQQQQQQQQQQQQQQQQQQQ H +Q ++Q +QQQQQQ QQ QQQ Q
Sbjct: 189 QQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQ 248
Query: 2108 QQQQQQQQHQQQQQQQ---AAPPQPQPQSQPQFQRQGLQQTQQQQ 2149
QQ QQQQH Q+Q + PP + GL + QQ
Sbjct: 249 MQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQ 293
Score = 87.4 bits (215), Expect = 1e-16
Identities = 53/108 (49%), Positives = 61/108 (56%)
Query: 2061 QQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQ 2120
QQ QQ QQQ QQ QQQQ ++ QQQQ Q+ ++QQ+Q Q QQQQQ QQQQ
Sbjct: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
Query: 2121 QQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQ 2168
QQQ Q Q Q Q Q Q+Q QQ QQQQQ + QQQ Q Q
Sbjct: 187 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQ 234
Score = 80.1 bits (196), Expect = 2e-14
Identities = 58/130 (44%), Positives = 61/130 (46%), Gaps = 45/130 (34%)
Query: 2079 IRQQQQQQILR------------------------------------------QQQQQQQ 2096
I QQ QQIL+ QQQQQQQ
Sbjct: 124 ITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQ 183
Query: 2097 QQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVR 2156
QQQQQQQQQQQQQQQQQQQ QQQQQQQ Q P Q + Q+ QQ QQQQQ AA
Sbjct: 184 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQ---QQQQQQQQLAAQQL 240
Query: 2157 QLQQQLSNTQ 2166
QQQL Q
Sbjct: 241 VFQQQLLQMQ 250
Score = 52.0 bits (123), Expect = 6e-06
Identities = 55/200 (27%), Positives = 75/200 (37%), Gaps = 42/200 (21%)
Query: 2011 TSTQRFSHQTLQQTPMISTMTPMSA-------QGVQAGVRSTAILPEQQQQQQQQQQQQQ 2063
++T+ S+ ++ Q M + + + A G + ST L QQQQ Q +Q
Sbjct: 5 SATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQL 64
Query: 2064 QQQQQQQQQQQQQYHIRQQQQQQILRQ--------------------------------- 2090
QQQ + + +Q+ Q++L +
Sbjct: 65 LLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHNTFAVPVSVAMMTPQVI 124
Query: 2091 --QQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQ 2148
QQ QQ QQQ QQ Q QQQQ QQQQ + Q Q Q QQ QQQ
Sbjct: 125 TPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQ 184
Query: 2149 QQTAALVRQLQQQLSNTQPQ 2168
QQ +Q QQQ Q Q
Sbjct: 185 QQQQQQQQQQQQQQQQQQQQ 204
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 116 bits (290), Expect = 3e-25
Identities = 70/137 (51%), Positives = 88/137 (64%), Gaps = 5/137 (3%)
Query: 2030 MTP--MSAQGVQAGVRSTAILPEQQQ---QQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQ 2084
MTP ++ Q +Q ++ + P+Q Q QQQQ QQQQ Q+ ++QQ+Q H++ QQ
Sbjct: 2 MTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQ 61
Query: 2085 QQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQ 2144
QQ +QQQQQQQQQQQQQQQQQQQQQQQQQQ QQQQQQ + Q Q Q Q+Q Q
Sbjct: 62 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 121
Query: 2145 TQQQQQTAALVRQLQQQ 2161
QQ ++QLQQQ
Sbjct: 122 QLVFQQQLLQMQQLQQQ 138
Score = 114 bits (285), Expect = 1e-24
Identities = 74/130 (56%), Positives = 83/130 (63%), Gaps = 13/130 (10%)
Query: 2047 ILPEQQQQQQQQQQQQQQQ-----QQQQ----QQQQQQQYHIRQQQQQQI-LRQQQQQQQ 2096
I P+Q QQ QQQ QQ QQQQ QQQQ Q+++ +QQ+Q + L QQQQQQQ
Sbjct: 7 ITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQ 66
Query: 2097 QQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVR 2156
QQQQQQQQQQQQQQQQQQQ QQQQQQQ Q P Q + Q+ QQ QQQQQ AA
Sbjct: 67 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQ---QQQQQQQQLAAQQL 123
Query: 2157 QLQQQLSNTQ 2166
QQQL Q
Sbjct: 124 VFQQQLLQMQ 133
Score = 111 bits (278), Expect = 7e-24
Identities = 75/151 (49%), Positives = 93/151 (61%), Gaps = 14/151 (9%)
Query: 2020 TLQQTPMISTMTPMSAQGVQAGVRST-AILPEQQQQQQQQQQQQQQ------QQQQQQQQ 2072
T QQ I +S Q +QA ++ A++ +QQQ Q+ ++QQ+Q QQQQQQQQ
Sbjct: 8 TPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQ 67
Query: 2073 QQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQ 2132
QQQQ +QQQQQQ +QQQQQQQQQQQQQQQ +Q ++QQQ QQQQQQ AA
Sbjct: 68 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA------- 120
Query: 2133 SQPQFQRQGLQQTQQQQQTAALVRQLQQQLS 2163
Q FQ+Q LQ Q QQQ L Q Q +S
Sbjct: 121 QQLVFQQQLLQMQQLQQQQHLLSLQRQGLIS 151
Score = 92.0 bits (227), Expect = 6e-18
Identities = 56/105 (53%), Positives = 65/105 (61%), Gaps = 5/105 (4%)
Query: 2050 EQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQ--QQQQQQ 2107
+QQQQQQQQQQQQQQQQQQQQQQQQQQ H +Q ++Q +QQQQQQ QQ QQQ Q
Sbjct: 72 QQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQ 131
Query: 2108 QQQQQQQQHQQQQQQQ---AAPPQPQPQSQPQFQRQGLQQTQQQQ 2149
QQ QQQQH Q+Q + PP + GL + QQ
Sbjct: 132 MQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQ 176
Score = 87.4 bits (215), Expect = 1e-16
Identities = 53/108 (49%), Positives = 61/108 (56%)
Query: 2061 QQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQ 2120
QQ QQ QQQ QQ QQQQ ++ QQQQ Q+ ++QQ+Q Q QQQQQ QQQQ
Sbjct: 10 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 69
Query: 2121 QQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQ 2168
QQQ Q Q Q Q Q Q+Q QQ QQQQQ + QQQ Q Q
Sbjct: 70 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQ 117
Score = 71.6 bits (174), Expect = 8e-12
Identities = 48/110 (43%), Positives = 56/110 (50%), Gaps = 18/110 (16%)
Query: 2060 QQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQ 2119
QQ QQ QQQ QQ + QQQQ +L+QQQ Q+ ++QQ+Q Q QQQQQQ QQQ
Sbjct: 10 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 69
Query: 2120 QQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQP 2169
QQQQ QQ QQQQQ +Q QQQ Q P
Sbjct: 70 QQQQQ------------------QQQQQQQQQQQQQQQQQQQQQQQQQHP 101
Score = 64.3 bits (155), Expect = 1e-09
Identities = 48/118 (40%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 2019 QTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYH 2078
Q LQQ Q Q + +QQQQQQQQQQQ +Q ++QQQQ
Sbjct: 57 QLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ----- 111
Query: 2079 IRQQQQQQILRQQ---QQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQS 2133
QQQQQQ+ QQ QQQ Q QQ QQQQ Q+Q Q A P Q PQ+
Sbjct: 112 --QQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQA 167
Score = 52.0 bits (123), Expect = 6e-06
Identities = 45/122 (36%), Positives = 52/122 (42%), Gaps = 23/122 (18%)
Query: 1992 QQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQ 2051
QQ Y QQ + L Q+ Q QQ Q Q +Q
Sbjct: 41 QQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ---------QQ 91
Query: 2052 QQQQQQQQ--------QQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQ 2103
QQQQQQQQ QQQQQQQQQQ QQ + QQQ+L+ QQ QQQQ Q
Sbjct: 92 QQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVF------QQQLLQMQQLQQQQHLLSLQ 145
Query: 2104 QQ 2105
+Q
Sbjct: 146 RQ 147
Score = 51.6 bits (122), Expect = 8e-06
Identities = 35/83 (42%), Positives = 39/83 (46%)
Query: 2086 QILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQT 2145
Q++ QQ QQ QQQ QQ Q QQQQ QQQQ + Q Q Q QQ
Sbjct: 5 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQ 64
Query: 2146 QQQQQTAALVRQLQQQLSNTQPQ 2168
QQQQQ +Q QQQ Q Q
Sbjct: 65 QQQQQQQQQQQQQQQQQQQQQQQ 87
Score = 38.1 bits (87), Expect = 0.095
Identities = 34/101 (33%), Positives = 38/101 (37%), Gaps = 16/101 (15%)
Query: 1990 HLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILP 2049
HLQ QQ Q+ Q QQ G QA
Sbjct: 55 HLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQA--------K 106
Query: 2050 EQQQQQQQQQQ--------QQQQQQQQQQQQQQQQYHIRQQ 2082
EQQQQQQQQQQ QQQ Q QQ QQQQ +++Q
Sbjct: 107 EQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQ 147
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 112 bits (279), Expect = 5e-24
Identities = 78/164 (47%), Positives = 93/164 (56%), Gaps = 25/164 (15%)
Query: 2026 MISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQ---QYHIRQQ 2082
++ST TP + Q ++ A+ +QQQQQ QQQQQ QQQQQQQQQQQ Q QQ
Sbjct: 143 VVSTATPQT----QLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQ 198
Query: 2083 QQQQILRQQQQQQQQQQQQQ-------QQQQQQQQQQQ----------QQHQQQQQQQAA 2125
Q Q +++QQQQ QQQQQQQQ Q QQQ QQQQQ QQ QQQQQQQ
Sbjct: 199 QFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQ 258
Query: 2126 PPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQP 2169
Q Q+QP Q+ +QQ Q + AL +QLQQ QP
Sbjct: 259 QQQQALQAQPPIQQPPMQQ-PQPPPSQALPQQLQQMHHTQHHQP 301
Score = 102 bits (254), Expect = 4e-21
Identities = 86/203 (42%), Positives = 97/203 (47%), Gaps = 21/203 (10%)
Query: 1986 DPTRHLQQRPSGYVHQQA----PTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAG 2041
DP LQ G A P G G + S + Q +S P G+
Sbjct: 80 DPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAP- 138
Query: 2042 VRSTAILPEQQQQQQQQQQQQQQQQQQQQQ--QQQQQYHIRQQQQQQILRQQQQQQQQQQ 2099
S A++ Q Q Q QQ QQQQQQQ QQQQQ ++QQQQQQ +Q Q QQ Q
Sbjct: 139 -HSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQ 197
Query: 2100 QQ-----QQQQQQQQQQQQQQH--------QQQQQQQAAPPQPQPQSQPQFQRQGLQQTQ 2146
QQ QQQQQ QQQQQQQQH QQQ QQQ Q Q Q Q Q+Q QQ Q
Sbjct: 198 QQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQ 257
Query: 2147 QQQQTAALVRQLQQQLSNTQPQP 2169
QQQQ A + QQ QPQP
Sbjct: 258 QQQQQALQAQPPIQQPPMQQPQP 280
Score = 101 bits (252), Expect = 7e-21
Identities = 97/258 (37%), Positives = 110/258 (42%), Gaps = 57/258 (22%)
Query: 1958 GPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFS 2017
G AG +PP P QS + + L +P AP H + +
Sbjct: 95 GAAGIGMPPR---GPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAP---HSMAVVSTAT 148
Query: 2018 HQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQ------------Q 2065
QT Q ++ Q Q + A L +QQQQQQQQQ Q QQ Q
Sbjct: 149 PQTQLQLQQVALQQQQQQQQFQQ--QQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQ 206
Query: 2066 QQQQQQQQQQQYHI---RQQQQQQILRQQQQ---------QQQQQQQQQQQQQQQQ---- 2109
QQQ QQQQQQQ H+ Q QQQI +QQQQ QQQQQQQQQQQQQQQQ
Sbjct: 207 QQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQA 266
Query: 2110 ---------QQQQ--------QQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTA 2152
QQ Q QQ QQ Q P PQPQ P Q Q Q Q QT
Sbjct: 267 QPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQP-SQLPPQSQTQ 325
Query: 2153 ALVRQLQQ---QLSNTQP 2167
LV Q Q Q+ TQP
Sbjct: 326 PLVSQAQALPGQMLYTQP 343
Score = 47.8 bits (112), Expect = 1e-04
Identities = 66/267 (24%), Positives = 90/267 (33%), Gaps = 26/267 (9%)
Query: 1894 KTSVYRQQQPAVPQGQRLRQQLQQSQGMLG---------QSSVHQMTPSSSYGLQTSQGY 1944
++++ +Q Q V Q Q+L+QQ QQ Q ++ Q Q+ + LQ Q
Sbjct: 193 QSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQ 252
Query: 1945 TPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGY---VHQ 2001
Q PP QP S + T+H Q P V Q
Sbjct: 253 QQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQ 312
Query: 2002 QAPTYGHGLTSTQRFSHQTLQQTP--MISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQ 2059
P+ + TQ Q Q P M+ T P+ V+ + P+ QQQQ Q
Sbjct: 313 NQPSQLPPQSQTQPLVSQA-QALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQ 371
Query: 2060 QQQQQQ------QQQQQQQQQQQYHIRQQ-----QQQQILRQQQQQQQQQQQQQQQQQQQ 2108
Q Q Q + Q HIR + I +Q Q Q
Sbjct: 372 TAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLP 431
Query: 2109 QQQQQQQHQQQQQQQAAPPQPQPQSQP 2135
QQ Q Q+ PP PQP QP
Sbjct: 432 MLSSPSPGQQVQTPQSMPPPPQPSPQP 458
Score = 47.0 bits (110), Expect = 2e-04
Identities = 65/266 (24%), Positives = 90/266 (33%), Gaps = 54/266 (20%)
Query: 1898 YRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHT 1957
++QQQ A Q Q+ +QQ QQ Q QS++ Q + + V QQ
Sbjct: 169 FQQQQQAALQQQQQQQQQQQFQAQ--QSAMQQQ----------------FQAVVQQQQ-- 208
Query: 1958 GPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFS 2017
Q Q H L+ QQ+ + QQ
Sbjct: 209 ---------QLQQQQQQQQH------LIKLHHQNQQQ----IQQQ--------------- 234
Query: 2018 HQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQY 2077
Q LQ+ + Q Q + A+ + QQ QQ Q Q QQ QQ +
Sbjct: 235 QQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMH 294
Query: 2078 HIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQF 2137
H + Q +Q Q Q Q Q Q Q Q Q Q PP ++
Sbjct: 295 HTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVV 354
Query: 2138 QRQGLQQTQQQQQTAALVRQLQQQLS 2163
Q+ +Q QQQQTA Q Q ++
Sbjct: 355 QQPPVQPQVQQQQTAVQTAQAAQMVA 380
Score = 41.6 bits (96), Expect = 0.009
Identities = 57/247 (23%), Positives = 79/247 (31%), Gaps = 26/247 (10%)
Query: 1899 RQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTG 1958
+QQQ Q Q+ +QQ Q+Q + Q + Q P S L + H H
Sbjct: 247 QQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQH-----HQP 301
Query: 1959 PAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQ------QRPSGYVH-----QQAPTYG 2007
P PP +QP Q S LV + L Q P +V QQ P
Sbjct: 302 PPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQP 361
Query: 2008 HGLTSTQRFSHQTLQQTPMISTMTPMSAQGV-QAGVRSTAILPEQQQQQQQQQQQQQQQQ 2066
Q+ + QT Q M++ M + + Q G+ A P +
Sbjct: 362 Q--VQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGR 419
Query: 2067 QQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAP 2126
Q Q + Q + QQ Q Q Q Q Q Q ++
Sbjct: 420 QPMAQ-------VSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG 472
Query: 2127 PQPQPQS 2133
P P P S
Sbjct: 473 PAPSPSS 479
Score = 32.7 bits (73), Expect = 4.0
Identities = 26/64 (40%), Positives = 27/64 (42%), Gaps = 19/64 (29%)
Query: 2107 QQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQ 2166
Q Q Q QQ QQQQQQ QQ QQQQQ A +Q QQQ Q
Sbjct: 150 QTQLQLQQVALQQQQQQ-------------------QQFQQQQQAALQQQQQQQQQQQFQ 190
Query: 2167 PQPS 2170
Q S
Sbjct: 191 AQQS 194
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 112 bits (279), Expect = 5e-24
Identities = 78/164 (47%), Positives = 93/164 (56%), Gaps = 25/164 (15%)
Query: 2026 MISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQ---QYHIRQQ 2082
++ST TP + Q ++ A+ +QQQQQ QQQQQ QQQQQQQQQQQ Q QQ
Sbjct: 143 VVSTATPQT----QLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQ 198
Query: 2083 QQQQILRQQQQQQQQQQQQQ-------QQQQQQQQQQQ----------QQHQQQQQQQAA 2125
Q Q +++QQQQ QQQQQQQQ Q QQQ QQQQQ QQ QQQQQQQ
Sbjct: 199 QFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQ 258
Query: 2126 PPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQP 2169
Q Q+QP Q+ +QQ Q + AL +QLQQ QP
Sbjct: 259 QQQQALQAQPPIQQPPMQQ-PQPPPSQALPQQLQQMHHTQHHQP 301
Score = 102 bits (254), Expect = 4e-21
Identities = 86/203 (42%), Positives = 97/203 (47%), Gaps = 21/203 (10%)
Query: 1986 DPTRHLQQRPSGYVHQQA----PTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAG 2041
DP LQ G A P G G + S + Q +S P G+
Sbjct: 80 DPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAP- 138
Query: 2042 VRSTAILPEQQQQQQQQQQQQQQQQQQQQQ--QQQQQYHIRQQQQQQILRQQQQQQQQQQ 2099
S A++ Q Q Q QQ QQQQQQQ QQQQQ ++QQQQQQ +Q Q QQ Q
Sbjct: 139 -HSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQ 197
Query: 2100 QQ-----QQQQQQQQQQQQQQH--------QQQQQQQAAPPQPQPQSQPQFQRQGLQQTQ 2146
QQ QQQQQ QQQQQQQQH QQQ QQQ Q Q Q Q Q+Q QQ Q
Sbjct: 198 QQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQ 257
Query: 2147 QQQQTAALVRQLQQQLSNTQPQP 2169
QQQQ A + QQ QPQP
Sbjct: 258 QQQQQALQAQPPIQQPPMQQPQP 280
Score = 101 bits (252), Expect = 7e-21
Identities = 97/258 (37%), Positives = 110/258 (42%), Gaps = 57/258 (22%)
Query: 1958 GPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFS 2017
G AG +PP P QS + + L +P AP H + +
Sbjct: 95 GAAGIGMPPR---GPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAP---HSMAVVSTAT 148
Query: 2018 HQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQ------------Q 2065
QT Q ++ Q Q + A L +QQQQQQQQQ Q QQ Q
Sbjct: 149 PQTQLQLQQVALQQQQQQQQFQQ--QQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQ 206
Query: 2066 QQQQQQQQQQQYHI---RQQQQQQILRQQQQ---------QQQQQQQQQQQQQQQQ---- 2109
QQQ QQQQQQQ H+ Q QQQI +QQQQ QQQQQQQQQQQQQQQQ
Sbjct: 207 QQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQA 266
Query: 2110 ---------QQQQ--------QQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTA 2152
QQ Q QQ QQ Q P PQPQ P Q Q Q Q QT
Sbjct: 267 QPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQP-SQLPPQSQTQ 325
Query: 2153 ALVRQLQQ---QLSNTQP 2167
LV Q Q Q+ TQP
Sbjct: 326 PLVSQAQALPGQMLYTQP 343
Score = 51.2 bits (121), Expect = 1e-05
Identities = 62/245 (25%), Positives = 85/245 (34%), Gaps = 22/245 (8%)
Query: 1894 KTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGL 1953
++++ +Q Q V Q Q+L+QQ QQ Q ++ +Q +Q Q ++ + L
Sbjct: 193 QSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQ------IQQQQQQLQRIAQLQL 246
Query: 1954 QQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTST 2013
QQ Q Q+ P P + P Q PS + QQ H T
Sbjct: 247 QQQQQQQQQQ--QQQQQQALQAQPPIQQPPMQQP----QPPPSQALPQQLQQMHH----T 296
Query: 2014 QRFSHQTLQQTPMISTMTPMSA---QGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQ 2070
Q Q P ++ P Q V LP Q Q + + QQ
Sbjct: 297 QHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQ 356
Query: 2071 QQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQ 2130
Q Q QQQQ + Q Q Q Q QQ Q Q+ PP PQ
Sbjct: 357 PPVQPQV---QQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQ 413
Query: 2131 PQSQP 2135
P QP
Sbjct: 414 PSPQP 418
Score = 43.5 bits (101), Expect = 0.002
Identities = 51/183 (27%), Positives = 63/183 (34%), Gaps = 43/183 (23%)
Query: 2014 QRFSHQTLQQTPMIST--MTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQ----- 2066
Q+ Q QQ +I Q Q ++ A L QQQQQQQQQQQQQQQQ
Sbjct: 208 QQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQ 267
Query: 2067 --------------------------QQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQ 2100
Q Q Q QQ + + Q Q Q Q
Sbjct: 268 PPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPP----QPQQPPVAQNQPSQLPPQSQ 323
Query: 2101 QQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQ 2160
Q Q Q Q Q PP ++ Q+ +Q QQQQTA Q Q
Sbjct: 324 TQPLVSQAQALPGQMLYTQ------PPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQ 377
Query: 2161 QLS 2163
++
Sbjct: 378 MVA 380
Score = 32.7 bits (73), Expect = 4.0
Identities = 26/64 (40%), Positives = 27/64 (42%), Gaps = 19/64 (29%)
Query: 2107 QQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQ 2166
Q Q Q QQ QQQQQQ QQ QQQQQ A +Q QQQ Q
Sbjct: 150 QTQLQLQQVALQQQQQQ-------------------QQFQQQQQAALQQQQQQQQQQQFQ 190
Query: 2167 PQPS 2170
Q S
Sbjct: 191 AQQS 194
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 110 bits (276), Expect = 1e-23
Identities = 111/336 (33%), Positives = 144/336 (42%), Gaps = 58/336 (17%)
Query: 1845 NQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPA 1904
+QP P R + M+ P T+ L G G + S + Q+
Sbjct: 3 HQPTPGN-------RGLTARMEVGPATETFVLELQCLEDGGPGPDTLSGGSGGSESQEEE 55
Query: 1905 VPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMV 1964
PQ + Q +G S + + T LQ Q L+Q P
Sbjct: 56 EPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQ----------LEQQPEP----- 100
Query: 1965 PPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQT 2024
QP P L LQQ+P QQ L+ Q+ HQ++
Sbjct: 101 ----QQQPQHEQLQQPQPHL-----ELQQQPQQDGQQQ-------LSQLQQEKHQSVHHQ 144
Query: 2025 PMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQ---QQYHIRQ 2081
+ + M Q + P+Q Q+QQ+ QQQQ+Q Q QQ Q+QQ QQ ++Q
Sbjct: 145 ELKPELQLMHQQ--------QQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQ 196
Query: 2082 QQQQQILRQQQQQQQQQQQ--QQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQR 2139
Q Q+Q L QQQQ+Q QQQQ QQQ+Q QQQQ QQQQ Q QQQQQ Q Q Q Q Q +
Sbjct: 197 QVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQ 256
Query: 2140 QGLQQTQQQ---QQTAALVRQL----QQQLSNTQPQ 2168
Q Q QQQ QQ A L +QL Q+QL Q Q
Sbjct: 257 QQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQ 292
Score = 109 bits (272), Expect = 3e-23
Identities = 101/334 (30%), Positives = 143/334 (42%), Gaps = 58/334 (17%)
Query: 1879 PTTMTGVMG-------LEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMT 1931
P T++G G EP +S R A + ++ + Q L + Q
Sbjct: 39 PDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQ- 97
Query: 1932 PSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHL 1991
P Q Q P H+ LQQ G + +QS H H
Sbjct: 98 PEPQQQPQHEQLQQPQ-PHLELQQQPQQDGQQQLSQLQQEKHQSVH------------HQ 144
Query: 1992 QQRPS-GYVHQQAPTYGHGLTSTQRFSHQTLQ-QTPMISTMTPMSAQG-VQAGVRSTAIL 2048
+ +P +HQQ + QR Q Q QT + Q +Q V+ +L
Sbjct: 145 ELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLL 204
Query: 2049 PEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQ-----------QQILRQQQQQQQQ 2097
+QQ+Q QQQQ QQQ+Q QQQQ QQQQ ++QQQQ QQ+L+QQQ Q QQ
Sbjct: 205 QQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQ 264
Query: 2098 Q----------------QQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQG 2141
Q QQ+Q QQQQQQQ QQQ +Q QQQQ PP +P+ + + + +
Sbjct: 265 QLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELEL 324
Query: 2142 L-------QQTQQQQQTAALVRQLQQQLSNTQPQ 2168
+ Q+ +QQ+Q ++L++Q Q Q
Sbjct: 325 MPVDLGSEQELEQQRQELERQQELERQQEQRQLQ 358
Score = 89.7 bits (221), Expect = 3e-17
Identities = 104/387 (26%), Positives = 153/387 (39%), Gaps = 47/387 (12%)
Query: 1820 LLHHPNPGS---ITHLNYRQGSIGLYTQNQPLPAGGPRVDPYR--------PVRLPMQKL 1868
+LH P PG+ + + + Q L GGP D Q+
Sbjct: 1 MLHQPTPGNRGLTARMEVGPATETFVLELQCLEDGGPGPDTLSGGSGGSESQEEEEPQER 60
Query: 1869 PTRPTYPGVLPTTMTGVMGLE--PSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGML---- 1922
+ P P V + E P + + + +Q PQ Q +QLQQ Q L
Sbjct: 61 NSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQ 120
Query: 1923 -----GQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQ-ST 1976
GQ + Q+ + Q P + + QQ P Q Q T
Sbjct: 121 QPQQDGQQQLSQLQQEKHQSVH-HQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQT 179
Query: 1977 HPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQ 2036
+ ++ LQQ+ V +Q Q Q LQQ + Q
Sbjct: 180 QQAQEQQVLQQQEQLQQQ----VQEQQLLQQQ---QEQLQQQQLLQQQEQLQQQQ-FQQQ 231
Query: 2037 GVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQ----QQQQILRQQQ 2092
Q + +L +QQ Q QQQ QQQQ Q QQQ +QQQ ++QQ QQ+Q+ +QQQ
Sbjct: 232 QEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQ 291
Query: 2093 QQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPP------QPQPQSQPQFQRQGLQQTQ 2146
QQ QQQQ+Q QQQQ Q + ++++ + P Q Q + + +RQ + Q
Sbjct: 292 QQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQ 351
Query: 2147 QQQQTAAL-----VRQLQQQLSNTQPQ 2168
Q+Q+ L ++QL+QQL Q Q
Sbjct: 352 QEQRQLQLKLQEELQQLEQQLEQQQQQ 378
Score = 77.8 bits (190), Expect = 1e-13
Identities = 75/281 (26%), Positives = 124/281 (44%), Gaps = 37/281 (13%)
Query: 1900 QQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGP 1959
QQQ PQ + +Q+LQQ Q L + LQ + V L Q
Sbjct: 155 QQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQV-----LQQQEQLQQQVQEQQLLQ---- 205
Query: 1960 AGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQR--FS 2017
Q L+ LQQ+ +Q L Q+
Sbjct: 206 --------------QQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQ 251
Query: 2018 HQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQ-QQQQQQQQQQQQQQQ 2076
Q LQQ + Q QA ++ +L +Q+Q QQQQQQQ QQQQ+Q QQQQ Q
Sbjct: 252 QQLLQQQQAQLQQQLLEQQ--QAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQP 309
Query: 2077 YHIRQQQQQQI--------LRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQ 2128
+ ++++++ L +Q+ +QQ+Q+ ++QQ+ ++QQ+Q+Q Q + Q++ +
Sbjct: 310 PPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLE 369
Query: 2129 PQ-PQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQ 2168
Q Q Q Q ++Q +Q + A +++Q +L+ QP+
Sbjct: 370 QQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPE 410
Score = 66.6 bits (161), Expect = 2e-10
Identities = 62/233 (26%), Positives = 102/233 (43%), Gaps = 25/233 (10%)
Query: 1900 QQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGP 1959
QQQ Q Q+L QQ +Q Q Q Q+ L QG + LQQ
Sbjct: 205 QQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQ---LQQQLLQQQQAQ 261
Query: 1960 AGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQ 2019
+ +Q Q L+ LQQ+ + QQ ++ Q
Sbjct: 262 LQQQLLEQQQAQLQQQL-------LLQQQEQLQQQQQQQLLQQ---------QQEQLQQQ 305
Query: 2020 TLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHI 2079
LQ P+ P + V+ + + EQ+ +QQ+Q+ ++QQ+ ++QQ+Q+Q Q +
Sbjct: 306 QLQPPPL----EPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKL 361
Query: 2080 RQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQ 2132
+++ QQ + +QQQQQ +QQ+ Q + + Q QQ+ Q + P QP+ Q
Sbjct: 362 QEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQ--QQEVQLELTPVQPELQ 412
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 96.3 bits (238), Expect = 3e-19
Identities = 58/143 (40%), Positives = 72/143 (50%), Gaps = 4/143 (2%)
Query: 2025 PMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQ 2084
P+IS+M + ST + P Q QQ Q Q QQQQQQQQQQ QQ QQ ++Q Q
Sbjct: 409 PLISSM----GTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQM 464
Query: 2085 QQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQ 2144
Q ++QQ QQQ Q QQ QQQQQ QQQ QQQ QQ + Q Q Q Q
Sbjct: 465 HQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPS 524
Query: 2145 TQQQQQTAALVRQLQQQLSNTQP 2167
+Q A+ + + + QP
Sbjct: 525 PRQHSPVASQITSPIPAIGSPQP 547
Score = 82.0 bits (201), Expect = 6e-15
Identities = 55/139 (39%), Positives = 63/139 (45%), Gaps = 1/139 (0%)
Query: 2013 TQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQ 2072
T R + + I+ P + T ++ Q Q QQ Q Q QQQ
Sbjct: 384 TMRLPMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQ 443
Query: 2073 QQQQYHIRQQQQQQILRQQQQQQQ-QQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQP 2131
QQQQ QQ QQQ L+Q Q QQ QQQ QQQ Q QQ QQ QQ QQQ Q Q
Sbjct: 444 QQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQ 503
Query: 2132 QSQPQFQRQGLQQTQQQQQ 2150
Q Q + Q Q LQ Q Q Q
Sbjct: 504 QLQQRLQLQQLQHMQHQSQ 522
Score = 74.7 bits (182), Expect = 9e-13
Identities = 82/271 (30%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 1891 SSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSH 1950
++Y+ S+ + + Q +R Q SS+ TP S +G ++ T
Sbjct: 315 AAYRASLVSKAAAESAEAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSASPQT----- 369
Query: 1951 VGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGL 2010
LQQ +P S + +P P +V PS + G
Sbjct: 370 --LQQS-------LPRSIAPKPLTMRLPMNQ--IVTSVTIAANMPSNIGAPLISSMG--- 415
Query: 2011 TSTQRFSHQTLQQTPMISTMT---PMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQ 2067
+T S + Q +P + T + Q Q + + +Q QQ Q QQ QQQ QQ
Sbjct: 416 -TTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQ 474
Query: 2068 Q------QQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQ 2121
Q QQ QQQQ H++QQ QQ L QQQ QQ+ Q QQ Q Q Q Q +QH
Sbjct: 475 QHFQHHMQQHLQQQQQHLQQQINQQQL-QQQLQQRLQLQQLQHMQHQSQPSPRQHSPVAS 533
Query: 2122 QQAAP----PQPQPQSQPQFQRQGLQQTQQQ 2148
Q +P PQP SQ Q Q Q QTQ Q
Sbjct: 534 QITSPIPAIGSPQPASQ-QHQSQIQSQTQTQ 563
Score = 43.5 bits (101), Expect = 0.002
Identities = 44/172 (25%), Positives = 59/172 (34%), Gaps = 15/172 (8%)
Query: 1946 PYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRP--SGYVHQQA 2003
P +S +G T V PS +Q +Q + +QQ+ +HQQ
Sbjct: 409 PLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQI 468
Query: 2004 PTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQ 2063
Q F H Q Q +Q + + +QQ QQ+ Q QQ Q
Sbjct: 469 QQQ----MQQQHFQHHMQQHLQQ-------QQQHLQQQINQQQL--QQQLQQRLQLQQLQ 515
Query: 2064 QQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQ 2115
Q Q Q +Q + Q I Q QQ Q Q Q Q Q Q Q
Sbjct: 516 HMQHQSQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQVLSQ 567
Score = 39.3 bits (90), Expect = 0.043
Identities = 64/243 (26%), Positives = 88/243 (36%), Gaps = 60/243 (24%)
Query: 1846 QPLPAGGPRVDPYRPV--RLPMQKLPTRPTYPGVLPTTM---------TGVMGLEPSSYK 1894
Q L PR +P+ RLPM ++ T T +P+ + T ++G PS+
Sbjct: 368 QTLQQSLPRSIAPKPLTMRLPMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQV 427
Query: 1895 T-SVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGL 1953
+ SV QQ Q Q+ +QQ Q Q Q HQM +Q
Sbjct: 428 SPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQ-------------- 473
Query: 1954 QQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTST 2013
QQH Q + H L +HLQQ+ + QQ L
Sbjct: 474 QQH-------------FQHHMQQH------LQQQQQHLQQQINQQQLQQQLQQRLQLQQL 514
Query: 2014 QRFSHQT----LQQTPMISTMT-PMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQ 2068
Q HQ+ Q +P+ S +T P+ A G P+ QQ Q Q Q Q Q Q
Sbjct: 515 QHMQHQSQPSPRQHSPVASQITSPIPAIG----------SPQPASQQHQSQIQSQTQTQV 564
Query: 2069 QQQ 2071
Q
Sbjct: 565 LSQ 567
Score = 32.0 bits (71), Expect = 6.8
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 14/57 (24%)
Query: 2112 QQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQ 2168
Q QQHQ Q QQQ Q+Q QQ QQ QQ Q+ QQ+ Q
Sbjct: 432 QTQQHQMQLQQQ--------------QQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQ 474
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 96.3 bits (238), Expect = 3e-19
Identities = 58/143 (40%), Positives = 72/143 (50%), Gaps = 4/143 (2%)
Query: 2025 PMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQ 2084
P+IS+M + ST + P Q QQ Q Q QQQQQQQQQQ QQ QQ ++Q Q
Sbjct: 414 PLISSM----GTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQM 469
Query: 2085 QQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQ 2144
Q ++QQ QQQ Q QQ QQQQQ QQQ QQQ QQ + Q Q Q Q
Sbjct: 470 HQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPS 529
Query: 2145 TQQQQQTAALVRQLQQQLSNTQP 2167
+Q A+ + + + QP
Sbjct: 530 PRQHSPVASQITSPIPAIGSPQP 552
Score = 82.0 bits (201), Expect = 6e-15
Identities = 55/139 (39%), Positives = 63/139 (45%), Gaps = 1/139 (0%)
Query: 2013 TQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQ 2072
T R + + I+ P + T ++ Q Q QQ Q Q QQQ
Sbjct: 389 TMRLPMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQ 448
Query: 2073 QQQQYHIRQQQQQQILRQQQQQQQ-QQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQP 2131
QQQQ QQ QQQ L+Q Q QQ QQQ QQQ Q QQ QQ QQ QQQ Q Q
Sbjct: 449 QQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQ 508
Query: 2132 QSQPQFQRQGLQQTQQQQQ 2150
Q Q + Q Q LQ Q Q Q
Sbjct: 509 QLQQRLQLQQLQHMQHQSQ 527
Score = 74.7 bits (182), Expect = 9e-13
Identities = 82/271 (30%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 1891 SSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSH 1950
++Y+ S+ + + Q +R Q SS+ TP S +G ++ T
Sbjct: 320 AAYRASLVSKAAAESAEAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSASPQT----- 374
Query: 1951 VGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGL 2010
LQQ +P S + +P P +V PS + G
Sbjct: 375 --LQQS-------LPRSIAPKPLTMRLPMNQ--IVTSVTIAANMPSNIGAPLISSMG--- 420
Query: 2011 TSTQRFSHQTLQQTPMISTMT---PMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQ 2067
+T S + Q +P + T + Q Q + + +Q QQ Q QQ QQQ QQ
Sbjct: 421 -TTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQ 479
Query: 2068 Q------QQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQ 2121
Q QQ QQQQ H++QQ QQ L QQQ QQ+ Q QQ Q Q Q Q +QH
Sbjct: 480 QHFQHHMQQHLQQQQQHLQQQINQQQL-QQQLQQRLQLQQLQHMQHQSQPSPRQHSPVAS 538
Query: 2122 QQAAP----PQPQPQSQPQFQRQGLQQTQQQ 2148
Q +P PQP SQ Q Q Q QTQ Q
Sbjct: 539 QITSPIPAIGSPQPASQ-QHQSQIQSQTQTQ 568
Score = 43.5 bits (101), Expect = 0.002
Identities = 44/172 (25%), Positives = 59/172 (34%), Gaps = 15/172 (8%)
Query: 1946 PYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRP--SGYVHQQA 2003
P +S +G T V PS +Q +Q + +QQ+ +HQQ
Sbjct: 414 PLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQI 473
Query: 2004 PTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQ 2063
Q F H Q Q +Q + + +QQ QQ+ Q QQ Q
Sbjct: 474 QQQ----MQQQHFQHHMQQHLQQ-------QQQHLQQQINQQQL--QQQLQQRLQLQQLQ 520
Query: 2064 QQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQ 2115
Q Q Q +Q + Q I Q QQ Q Q Q Q Q Q Q
Sbjct: 521 HMQHQSQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQVLSQ 572
Score = 39.3 bits (90), Expect = 0.043
Identities = 64/243 (26%), Positives = 88/243 (36%), Gaps = 60/243 (24%)
Query: 1846 QPLPAGGPRVDPYRPV--RLPMQKLPTRPTYPGVLPTTM---------TGVMGLEPSSYK 1894
Q L PR +P+ RLPM ++ T T +P+ + T ++G PS+
Sbjct: 373 QTLQQSLPRSIAPKPLTMRLPMNQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQV 432
Query: 1895 T-SVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGL 1953
+ SV QQ Q Q+ +QQ Q Q Q HQM +Q
Sbjct: 433 SPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQ-------------- 478
Query: 1954 QQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTST 2013
QQH Q + H L +HLQQ+ + QQ L
Sbjct: 479 QQH-------------FQHHMQQH------LQQQQQHLQQQINQQQLQQQLQQRLQLQQL 519
Query: 2014 QRFSHQT----LQQTPMISTMT-PMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQ 2068
Q HQ+ Q +P+ S +T P+ A G P+ QQ Q Q Q Q Q Q
Sbjct: 520 QHMQHQSQPSPRQHSPVASQITSPIPAIG----------SPQPASQQHQSQIQSQTQTQV 569
Query: 2069 QQQ 2071
Q
Sbjct: 570 LSQ 572
Score = 32.0 bits (71), Expect = 6.8
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 14/57 (24%)
Query: 2112 QQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQ 2168
Q QQHQ Q QQQ Q+Q QQ QQ QQ Q+ QQ+ Q
Sbjct: 437 QTQQHQMQLQQQ--------------QQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQ 479
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 94.7 bits (234), Expect = 9e-19
Identities = 119/481 (24%), Positives = 177/481 (36%), Gaps = 72/481 (14%)
Query: 1731 RPRPRAYYLEPLPLPPEDEEPPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGK 1790
+P+P + P P P PT + K + P P PP+ E ++ +
Sbjct: 1870 QPQPSPVSMSPAGFPSVARTQP-PTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREA 1928
Query: 1791 KRSQPATKTE-DYGMGPGRSG--PYGVTVPPDLLHHPNPGSITHLNYRQGSIGLYTQNQP 1847
++ Q + + M PGR+G G + P L+ P P ++ G + Q P
Sbjct: 1929 QQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQW-QQAP 1987
Query: 1848 LPAGGPRVDPYRPV-RLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVP 1906
LP P RPV + Q P P V P + PS+ + + + P+ P
Sbjct: 1988 LPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPR-----SISPSALQDLLRTLKSPSSP 2042
Query: 1907 QGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVP- 1965
Q Q+ + +S L + + Q T + G P GLQ G M P
Sbjct: 2043 QQQQQVLNILKSNPQLMAAFIKQRTAKY---VANQPGMQP---QPGLQSQPG----MQPQ 2092
Query: 1966 PSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTP 2025
P QP + + P QQ+ G ++ Q Q + P
Sbjct: 2093 PGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQG----------QALNIMNPGHNP 2142
Query: 2026 MISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQ------------------- 2066
+++M P + ++ +L +QQQQQQQQQQQQQQQQ
Sbjct: 2143 NMASMNPQYREMLRR-----QLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQ 2197
Query: 2067 --------QQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQ-----QQQQQQQQQQQQQQ 2113
QQQQ+ QQ ++ Q+ Q Q Q Q QQ QQ+
Sbjct: 2198 GPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRI 2257
Query: 2114 QQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQ---QQQTAALVRQLQQQLSNTQPQPS 2170
Q QQ +QQ +P QP P S Q G Q QQ +L Q++ P+P
Sbjct: 2258 LQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQ 2317
Query: 2171 T 2171
+
Sbjct: 2318 S 2318
Score = 37.0 bits (84), Expect = 0.21
Identities = 83/397 (20%), Positives = 121/397 (30%), Gaps = 70/397 (17%)
Query: 1834 YRQGSIGLYTQNQP-LPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSS 1892
++QG +G NQP LPA G + P +P + P P LP V S
Sbjct: 636 HKQGILG----NQPALPAPGAQ-----PPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSF 686
Query: 1893 YKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMT--------------------- 1931
S+ Q P P G R + S M SV M
Sbjct: 687 NPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMM 746
Query: 1932 ---------------PSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPP--SYSSQPYQ 1974
PSSS + G P + G+ Q P + P Q Q
Sbjct: 747 AQAPAQSQFLPQNQFPSSSGAMSVGMGQPP--AQTGVSQGQVPGAALPNPLNMLGPQASQ 804
Query: 1975 STHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMIST-MTPM 2033
P + + PT +G Q T G+T Q + T TP+ S+ TP
Sbjct: 805 LPCPPVTQSPLHPTPPPASTAAGMPSLQHTT-PPGMTPPQP-AAPTQPSTPVSSSGQTPT 862
Query: 2034 SAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQ------QQQQQQQQYHIRQQQQQQI 2087
G T P Q Q Q Q Q Q Q QQQ + Q
Sbjct: 863 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP 922
Query: 2088 LRQQQQQQQQQQQQQQQQQQQQQQQQQQH------QQQQQQQAAPPQPQP-----QSQPQ 2136
L Q + + QQ + + + QA +P P + + +
Sbjct: 923 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE 982
Query: 2137 FQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPSTNI 2173
+ LQ Q ++ + Q + + + +P +
Sbjct: 983 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKV 1019
Score = 32.0 bits (71), Expect = 6.8
Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 12/61 (19%)
Query: 2088 LRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQ------------QQQQAAPPQPQPQSQP 2135
LRQQQ Q + QQ Q +++ + QQ QQ + P PQP +QP
Sbjct: 1812 LRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQP 1871
Query: 2136 Q 2136
Q
Sbjct: 1872 Q 1872
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 94.7 bits (234), Expect = 9e-19
Identities = 119/481 (24%), Positives = 177/481 (36%), Gaps = 72/481 (14%)
Query: 1731 RPRPRAYYLEPLPLPPEDEEPPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGK 1790
+P+P + P P P PT + K + P P PP+ E ++ +
Sbjct: 1908 QPQPSPVSMSPAGFPSVARTQP-PTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREA 1966
Query: 1791 KRSQPATKTE-DYGMGPGRSG--PYGVTVPPDLLHHPNPGSITHLNYRQGSIGLYTQNQP 1847
++ Q + + M PGR+G G + P L+ P P ++ G + Q P
Sbjct: 1967 QQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQW-QQAP 2025
Query: 1848 LPAGGPRVDPYRPV-RLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVP 1906
LP P RPV + Q P P V P + PS+ + + + P+ P
Sbjct: 2026 LPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPR-----SISPSALQDLLRTLKSPSSP 2080
Query: 1907 QGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVP- 1965
Q Q+ + +S L + + Q T + G P GLQ G M P
Sbjct: 2081 QQQQQVLNILKSNPQLMAAFIKQRTAKY---VANQPGMQP---QPGLQSQPG----MQPQ 2130
Query: 1966 PSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTP 2025
P QP + + P QQ+ G ++ Q Q + P
Sbjct: 2131 PGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQG----------QALNIMNPGHNP 2180
Query: 2026 MISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQ------------------- 2066
+++M P + ++ +L +QQQQQQQQQQQQQQQQ
Sbjct: 2181 NMASMNPQYREMLRR-----QLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQ 2235
Query: 2067 --------QQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQ-----QQQQQQQQQQQQQQ 2113
QQQQ+ QQ ++ Q+ Q Q Q Q QQ QQ+
Sbjct: 2236 GPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRI 2295
Query: 2114 QQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQ---QQQTAALVRQLQQQLSNTQPQPS 2170
Q QQ +QQ +P QP P S Q G Q QQ +L Q++ P+P
Sbjct: 2296 LQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQ 2355
Query: 2171 T 2171
+
Sbjct: 2356 S 2356
Score = 37.0 bits (84), Expect = 0.21
Identities = 83/397 (20%), Positives = 121/397 (30%), Gaps = 70/397 (17%)
Query: 1834 YRQGSIGLYTQNQP-LPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSS 1892
++QG +G NQP LPA G + P +P + P P LP V S
Sbjct: 674 HKQGILG----NQPALPAPGAQ-----PPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSF 724
Query: 1893 YKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMT--------------------- 1931
S+ Q P P G R + S M SV M
Sbjct: 725 NPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMM 784
Query: 1932 ---------------PSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPP--SYSSQPYQ 1974
PSSS + G P + G+ Q P + P Q Q
Sbjct: 785 AQAPAQSQFLPQNQFPSSSGAMSVGMGQPP--AQTGVSQGQVPGAALPNPLNMLGPQASQ 842
Query: 1975 STHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMIST-MTPM 2033
P + + PT +G Q T G+T Q + T TP+ S+ TP
Sbjct: 843 LPCPPVTQSPLHPTPPPASTAAGMPSLQHTT-PPGMTPPQP-AAPTQPSTPVSSSGQTPT 900
Query: 2034 SAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQ------QQQQQQQQYHIRQQQQQQI 2087
G T P Q Q Q Q Q Q Q QQQ + Q
Sbjct: 901 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP 960
Query: 2088 LRQQQQQQQQQQQQQQQQQQQQQQQQQQH------QQQQQQQAAPPQPQP-----QSQPQ 2136
L Q + + QQ + + + QA +P P + + +
Sbjct: 961 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE 1020
Query: 2137 FQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPSTNI 2173
+ LQ Q ++ + Q + + + +P +
Sbjct: 1021 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKV 1057
Score = 32.0 bits (71), Expect = 6.8
Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 12/61 (19%)
Query: 2088 LRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQ------------QQQQAAPPQPQPQSQP 2135
LRQQQ Q + QQ Q +++ + QQ QQ + P PQP +QP
Sbjct: 1850 LRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQP 1909
Query: 2136 Q 2136
Q
Sbjct: 1910 Q 1910
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 93.2 bits (230), Expect = 2e-18
Identities = 79/229 (34%), Positives = 92/229 (40%), Gaps = 10/229 (4%)
Query: 1940 TSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYV 1999
+ QG+T + + Q P M+ +Q Q HP HLQ + +
Sbjct: 377 SQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHP---------VLHLQPQQIMQL 427
Query: 2000 HQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQ 2059
QQ Q+ H QQ P Q + P QQ + QQQ
Sbjct: 428 QQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQ 487
Query: 2060 QQQQQQQQQQQQQ-QQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQ 2118
Q QQQ QQQ Q Q H QQQQ L+QQ QQQQQQQ QQQQ Q+ QQQ QQ
Sbjct: 488 LQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQ 547
Query: 2119 QQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQP 2167
Q Q Q AP Q Q Q Q QQQQQ Q QL P
Sbjct: 548 QMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDP 596
Score = 91.3 bits (225), Expect = 9e-18
Identities = 81/207 (39%), Positives = 98/207 (47%), Gaps = 32/207 (15%)
Query: 1983 TLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSH-QTLQQTPMISTMTPMSAQGVQAG 2041
TL PT++L+Q+ + H Q GH + FS + +T M+ Q Q
Sbjct: 362 TLSAPTKNLEQQVN---HSQQ---GHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHP 415
Query: 2042 VRSTAILPEQQQQQQQQQQQQQQQQ------------QQQQQQQQQQYHIRQQQ----QQ 2085
V + P+Q Q QQQQQQQ QQ QQQQQQQ + QQQ QQ
Sbjct: 416 VLH--LQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQ 473
Query: 2086 QILRQQQQQQQQQQQQQQQQQ---QQQQQQQQQHQQQQQQQAAPPQP----QPQSQPQFQ 2138
Q+ QQ + QQQ Q QQQ QQQ Q QQHQ QQQQ A Q Q Q Q Q Q
Sbjct: 474 QLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQ 533
Query: 2139 RQGLQQTQQQQQTAALVRQLQQQLSNT 2165
+Q LQ+ QQQQ + Q LS T
Sbjct: 534 QQQLQRMHQQQQQQQMQSQTAPHLSQT 560
Score = 85.5 bits (210), Expect = 5e-16
Identities = 69/144 (47%), Positives = 74/144 (51%), Gaps = 22/144 (15%)
Query: 2047 ILPEQQQQQQQQQQQQQQQQQQQQQQQQQQY-HIRQQQQQQILRQ-----------QQQQ 2094
+ PE QQQQQ QQQQQQ Q QQ ++QQQQQQI +Q QQQQ
Sbjct: 394 VTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQ 453
Query: 2095 QQQQQQQQQ-QQQQQQQQQQQQHQQQQ----QQQAAPPQPQPQSQPQFQRQGLQQTQQQQ 2149
QQQQ Q QQQ Q QQQ H QQ QQQ P Q Q Q QF + LQQ Q QQ
Sbjct: 454 QQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQ--LQQHQLQQ 511
Query: 2150 QTAALVRQLQQQLSNTQPQPSTNI 2173
Q A QLQQQ S Q Q I
Sbjct: 512 QQLA---QLQQQHSLLQQQQQQQI 532
Score = 72.8 bits (177), Expect = 3e-12
Identities = 67/217 (30%), Positives = 85/217 (39%), Gaps = 38/217 (17%)
Query: 1899 RQQQPAVP-QGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHT 1957
+QQ P + Q Q++ Q QQ Q + Q Q P + Q Q + QQ
Sbjct: 411 QQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHP-FSQQQQQQQQAHPHQFSQQQLQ 469
Query: 1958 GPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFS 2017
P + PP +P Q P QQ+ H L Q+
Sbjct: 470 FPQQQLHPPQQLHRPQQQLQP------------FQQQ-------------HAL---QQQF 501
Query: 2018 HQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQY 2077
HQ Q + + Q ++L +QQQQQ QQQQ Q+ QQQQQQQ Q Q
Sbjct: 502 HQLQQHQLQQQQLAQLQQQ--------HSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQT 553
Query: 2078 HIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQ 2114
Q Q L+ Q QQ QQQQQQQ QQ Q
Sbjct: 554 APHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQ 590
Score = 61.2 bits (147), Expect = 1e-08
Identities = 55/163 (33%), Positives = 70/163 (42%), Gaps = 17/163 (10%)
Query: 2019 QTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQ----QQQQQQ 2074
+TL+ + + M+ A + T P + +QQ QQ Q +
Sbjct: 336 RTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVT 395
Query: 2075 QQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQ-QQQQQQAAPPQP---- 2129
+ H+ QQQQQ QQQQQQ Q QQ Q QQQQQ Q QQ PP P
Sbjct: 396 PETHMLQQQQQA----QQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQ 451
Query: 2130 ---QPQSQP-QFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQ 2168
Q Q+ P QF +Q LQ QQQ + + QQQL Q Q
Sbjct: 452 QQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQ 494
>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
Length = 1161
Score = 89.7 bits (221), Expect = 3e-17
Identities = 52/105 (49%), Positives = 57/105 (54%), Gaps = 1/105 (0%)
Query: 2049 PEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQ 2108
P QQQQQQQQQQQQQQQQQQQQQQQQQQ H +L+ QQ Q QQQQ QQ
Sbjct: 458 PHQQQQQQQQQQQQQQQQQQQQQQQQQQQH-HHHHHHHLLQDAYMQQYQHATQQQQMLQQ 516
Query: 2109 QQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAA 2153
Q +Q Q P Q FQ+Q L Q Q QQ A+
Sbjct: 517 QFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLAQHQPSQQQAS 561
Score = 84.0 bits (206), Expect = 2e-15
Identities = 59/129 (45%), Positives = 67/129 (51%), Gaps = 21/129 (16%)
Query: 2047 ILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQ 2106
IL Q QQ QQ + QQ QQ + QQ H++ + Q QQQQQQQQQQQQQQQQQ
Sbjct: 421 ILLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQHRHPHQ---QQQQQQQQQQQQQQQQQ 477
Query: 2107 QQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQL---S 2163
QQQQQQQQQH Q + +Q TQQQQ LQQQ S
Sbjct: 478 QQQQQQQQQHHHHHHHHLL--------QDAYMQQYQHATQQQQ-------MLQQQFLMHS 522
Query: 2164 NTQPQPSTN 2172
QPQPS +
Sbjct: 523 VYQPQPSAS 531
Score = 82.8 bits (203), Expect = 3e-15
Identities = 64/145 (44%), Positives = 69/145 (47%), Gaps = 28/145 (19%)
Query: 2049 PEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQ 2108
P+Q QQ + QQ QQ + QQ Q H QQQQQQ +QQQQQQQQQQQQQQQQQQQ
Sbjct: 428 PQQPPQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQ--QQQQQQQQQQQQQQQQQQQQ 485
Query: 2109 QQ-------------QQQQQHQQQQQQ---------QAAPPQPQPQSQPQFQRQGLQQTQ 2146
Q QQ QH QQQQ PQP P Q QQ
Sbjct: 486 QHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQYPTMMPQ-YQQAF 544
Query: 2147 QQQQTAALVRQLQQQLSN---TQPQ 2168
QQQ A + QQQ S T PQ
Sbjct: 545 FQQQMLAQHQPSQQQASPEYLTSPQ 569
Score = 57.0 bits (136), Expect = 2e-07
Identities = 42/110 (38%), Positives = 51/110 (46%), Gaps = 10/110 (9%)
Query: 2050 EQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQ---QQQQILRQQQQQQQQQQQQQQQQQ 2106
+QQQQQQQQQQQQQ Q Y + Q QQQQ+L+QQ Q Q Q
Sbjct: 473 QQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQ 532
Query: 2107 QQQQQQQQQHQQQQQQQAAPPQP-QPQSQPQFQRQGLQQTQQQQQTAALV 2155
Q Q QQQ A QP Q Q+ P++ T Q+ + ALV
Sbjct: 533 YPTMMPQYQQAFFQQQMLAQHQPSQQQASPEY------LTSPQEFSPALV 576
Score = 43.5 bits (101), Expect = 0.002
Identities = 46/185 (24%), Positives = 60/185 (32%), Gaps = 11/185 (5%)
Query: 1953 LQQHTGPAGTMVPPSYSS-QPYQSTHPSTNPTLV--------DPTRH--LQQRPSGYVHQ 2001
+Q P + P + + +P + P P ++ P +H LQQ G
Sbjct: 389 IQSSATPVKVLAPGEFGNHRPKGALRPGNGPEILLGQGPPQQPPQQHRVLQQLQQGDWRL 448
Query: 2002 QAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQ 2061
Q H Q+ Q QQ Q Q L + QQ Q
Sbjct: 449 QQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHAT 508
Query: 2062 QQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQ 2121
QQQQ QQQ Y + Q Q QQ QQQ Q Q QQQ
Sbjct: 509 QQQQMLQQQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLAQHQPSQQQASPEYLTSP 568
Query: 2122 QQAAP 2126
Q+ +P
Sbjct: 569 QEFSP 573
Score = 32.7 bits (73), Expect = 4.0
Identities = 31/205 (15%), Positives = 74/205 (36%), Gaps = 22/205 (10%)
Query: 1983 TLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQ-----TPMISTMTPMSAQG 2037
+L P H + P G V P H + ++ H ++ Q P+ + T +++
Sbjct: 665 SLSAPHNHPPEDPFGSV----PFISHSGSPEKKAEHSSINQENGTANPIKNGKTSPASKD 720
Query: 2038 VQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQ 2097
+ G +++ Q Q Q+ + + + + +Q +++L+ +Q
Sbjct: 721 QRTGKKTSV------QGQVQKGNDESESDFESDPPSPKSSEEEEQDDEEVLQGEQGDFND 774
Query: 2098 QQQQQQQ-------QQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQ 2150
+ + + ++++++H + A + S R G TQ
Sbjct: 775 DDTEPENLGHRPLLMDSEDEEEEEKHSSDSDYEQAKAKYSDMSSVYRDRSGSGPTQDLNT 834
Query: 2151 TAALVRQLQQQLSNTQPQPSTNIFG 2175
QL ++ P+ ++FG
Sbjct: 835 ILLTSAQLSSDVAVETPKQEFDVFG 859
Score = 32.3 bits (72), Expect = 5.2
Identities = 38/153 (24%), Positives = 52/153 (33%), Gaps = 14/153 (9%)
Query: 1898 YRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHT 1957
++QQQ Q Q+ +QQ QQ Q Q H + Y H QQ
Sbjct: 459 HQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHH-----HHHHLLQDAYMQQYQHATQQQQM 513
Query: 1958 GPAGTMVPPSYSSQPYQSTHPSTNP----TLVDPTRHLQQRPSGYVHQQAPTYGHGLTST 2013
++ Y QP S +P+ P Q +PS Q +P Y LTS
Sbjct: 514 LQQQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLAQHQPS--QQQASPEY---LTSP 568
Query: 2014 QRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTA 2046
Q FS + T + + RS A
Sbjct: 569 QEFSPALVSYTSSLPAQVGTIMDSSYSANRSVA 601
>gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens]
Length = 662
Score = 89.7 bits (221), Expect = 3e-17
Identities = 52/105 (49%), Positives = 57/105 (54%), Gaps = 1/105 (0%)
Query: 2049 PEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQ 2108
P QQQQQQQQQQQQQQQQQQQQQQQQQQ H +L+ QQ Q QQQQ QQ
Sbjct: 458 PHQQQQQQQQQQQQQQQQQQQQQQQQQQQH-HHHHHHHLLQDAYMQQYQHATQQQQMLQQ 516
Query: 2109 QQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAA 2153
Q +Q Q P Q FQ+Q L Q Q QQ A+
Sbjct: 517 QFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLAQHQPSQQQAS 561
Score = 84.0 bits (206), Expect = 2e-15
Identities = 59/129 (45%), Positives = 67/129 (51%), Gaps = 21/129 (16%)
Query: 2047 ILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQ 2106
IL Q QQ QQ + QQ QQ + QQ H++ + Q QQQQQQQQQQQQQQQQQ
Sbjct: 421 ILLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQHRHPHQ---QQQQQQQQQQQQQQQQQ 477
Query: 2107 QQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQL---S 2163
QQQQQQQQQH Q + +Q TQQQQ LQQQ S
Sbjct: 478 QQQQQQQQQHHHHHHHHLL--------QDAYMQQYQHATQQQQ-------MLQQQFLMHS 522
Query: 2164 NTQPQPSTN 2172
QPQPS +
Sbjct: 523 VYQPQPSAS 531
Score = 82.8 bits (203), Expect = 3e-15
Identities = 64/145 (44%), Positives = 69/145 (47%), Gaps = 28/145 (19%)
Query: 2049 PEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQ 2108
P+Q QQ + QQ QQ + QQ Q H QQQQQQ +QQQQQQQQQQQQQQQQQQQ
Sbjct: 428 PQQPPQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQ--QQQQQQQQQQQQQQQQQQQQ 485
Query: 2109 QQ-------------QQQQQHQQQQQQ---------QAAPPQPQPQSQPQFQRQGLQQTQ 2146
Q QQ QH QQQQ PQP P Q QQ
Sbjct: 486 QHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQYPTMMPQ-YQQAF 544
Query: 2147 QQQQTAALVRQLQQQLSN---TQPQ 2168
QQQ A + QQQ S T PQ
Sbjct: 545 FQQQMLAQHQPSQQQASPEYLTSPQ 569
Score = 57.0 bits (136), Expect = 2e-07
Identities = 42/110 (38%), Positives = 51/110 (46%), Gaps = 10/110 (9%)
Query: 2050 EQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQ---QQQQILRQQQQQQQQQQQQQQQQQ 2106
+QQQQQQQQQQQQQ Q Y + Q QQQQ+L+QQ Q Q Q
Sbjct: 473 QQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQ 532
Query: 2107 QQQQQQQQQHQQQQQQQAAPPQP-QPQSQPQFQRQGLQQTQQQQQTAALV 2155
Q Q QQQ A QP Q Q+ P++ T Q+ + ALV
Sbjct: 533 YPTMMPQYQQAFFQQQMLAQHQPSQQQASPEY------LTSPQEFSPALV 576
Score = 43.5 bits (101), Expect = 0.002
Identities = 46/185 (24%), Positives = 60/185 (32%), Gaps = 11/185 (5%)
Query: 1953 LQQHTGPAGTMVPPSYSS-QPYQSTHPSTNPTLV--------DPTRH--LQQRPSGYVHQ 2001
+Q P + P + + +P + P P ++ P +H LQQ G
Sbjct: 389 IQSSATPVKVLAPGEFGNHRPKGALRPGNGPEILLGQGPPQQPPQQHRVLQQLQQGDWRL 448
Query: 2002 QAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQ 2061
Q H Q+ Q QQ Q Q L + QQ Q
Sbjct: 449 QQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHAT 508
Query: 2062 QQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQ 2121
QQQQ QQQ Y + Q Q QQ QQQ Q Q QQQ
Sbjct: 509 QQQQMLQQQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLAQHQPSQQQASPEYLTSP 568
Query: 2122 QQAAP 2126
Q+ +P
Sbjct: 569 QEFSP 573
Score = 32.3 bits (72), Expect = 5.2
Identities = 38/153 (24%), Positives = 52/153 (33%), Gaps = 14/153 (9%)
Query: 1898 YRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHT 1957
++QQQ Q Q+ +QQ QQ Q Q H + Y H QQ
Sbjct: 459 HQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHH-----HHHHLLQDAYMQQYQHATQQQQM 513
Query: 1958 GPAGTMVPPSYSSQPYQSTHPSTNP----TLVDPTRHLQQRPSGYVHQQAPTYGHGLTST 2013
++ Y QP S +P+ P Q +PS Q +P Y LTS
Sbjct: 514 LQQQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLAQHQPS--QQQASPEY---LTSP 568
Query: 2014 QRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTA 2046
Q FS + T + + RS A
Sbjct: 569 QEFSPALVSYTSSLPAQVGTIMDSSYSANRSVA 601
>gi|4507379 TATA box binding protein [Homo sapiens]
Length = 339
Score = 87.8 bits (216), Expect = 1e-16
Identities = 72/173 (41%), Positives = 87/173 (50%), Gaps = 23/173 (13%)
Query: 2004 PTYGHGLTSTQRFSHQTLQQ-TPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQ 2062
P Y GL S Q + +PM+ T ++ Q +Q S +IL EQQ+QQQQQQ Q
Sbjct: 8 PPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQ-NTNSLSILEEQQRQQQQQQ--Q 64
Query: 2063 QQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQ-------QQQQQQQQQQQQQQQ 2115
QQQQQQQQQQQQQQ QQQQQQ QQQQQQQQQQQ QQ QQ Q Q
Sbjct: 65 QQQQQQQQQQQQQQ----QQQQQQ---QQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQ 117
Query: 2116 HQQQQQQQAAPPQPQPQSQPQFQRQGLQQT-----QQQQQTAALVRQLQQQLS 2163
Q Q P P + P + T +++ +V QLQ +S
Sbjct: 118 APQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVS 170
Score = 58.9 bits (141), Expect = 5e-08
Identities = 34/64 (53%), Positives = 39/64 (60%), Gaps = 4/64 (6%)
Query: 2105 QQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSN 2164
++QQ+QQQQQQ QQQQQQQ Q Q Q Q Q Q+Q QQ QQQQQ A +QQ S
Sbjct: 53 EEQQRQQQQQQQQQQQQQQ----QQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQ 108
Query: 2165 TQPQ 2168
Q
Sbjct: 109 QATQ 112
Score = 53.1 bits (126), Expect = 3e-06
Identities = 29/63 (46%), Positives = 37/63 (58%)
Query: 2110 QQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQP 2169
++QQ+Q QQQQQQQ Q Q Q Q Q Q+Q QQ QQQQQ A+ QQ ++ Q
Sbjct: 53 EEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQ 112
Query: 2170 STN 2172
T+
Sbjct: 113 GTS 115
Score = 35.4 bits (80), Expect = 0.62
Identities = 42/167 (25%), Positives = 61/167 (36%), Gaps = 5/167 (2%)
Query: 1835 RQGSIGLYTQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYK 1894
+ S+ Y Q P G + P P+ PM T T + T ++ + +
Sbjct: 3 QNNSLPPYAQGLASPQGA--MTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQ 60
Query: 1895 TSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQ 1954
+QQQ Q Q+ +QQ QQ Q Q Q +++ TSQ T S Q
Sbjct: 61 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQ 120
Query: 1955 QHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQ 2001
T P ++ Y S P T T + P + SG V Q
Sbjct: 121 LFHSQTLTTAPLPGTTPLYPS--PMTPMTPITPATPASE-SSGIVPQ 164
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 85.9 bits (211), Expect = 4e-16
Identities = 102/341 (29%), Positives = 136/341 (39%), Gaps = 43/341 (12%)
Query: 1845 NQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPA 1904
+QP PAG P V P + Q P + T G + + KTSV P
Sbjct: 2532 SQP-PAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTGGSAAVLAGTIKTSVTGTSMPT 2590
Query: 1905 -VPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTM 1963
G + + QS ++ + G T+ G + V HT P
Sbjct: 2591 GAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGALTTPGGSAPAQVV----HTQP---- 2642
Query: 1964 VPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYG-HGLTSTQRFSHQTLQ 2022
PP P +T P LV A T G +TS + T
Sbjct: 2643 -PPRAVGSPATAT-----PDLVS---------------MATTQGVRAVTSVTASAVVTTN 2681
Query: 2023 QTPMIS---TMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHI 2079
TP+ + ++ P +Q + I P Q +QQQQQQQQQQQQQQQQQQQQ
Sbjct: 2682 LTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQ 2741
Query: 2080 RQQQQQQILRQQQQQQQQQQQQQQQQQQQ---QQQQQQQHQQQQQQQAAPPQPQPQSQPQ 2136
+QQQQQ Q Q Q Q Q Q Q + + + + Q+Q+ PPQP P PQ
Sbjct: 2742 QQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPP---PQ 2798
Query: 2137 FQRQGLQQTQQ-QQQTAALVRQLQQQLSN-TQPQPSTNIFG 2175
Q Q T Q Q QT+ +Q QL+ T P+P + G
Sbjct: 2799 AQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTG 2839
Score = 55.1 bits (131), Expect = 8e-07
Identities = 81/320 (25%), Positives = 109/320 (34%), Gaps = 60/320 (18%)
Query: 1864 PMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLG 1923
P Q P P P G +P + +V Q QP Q+Q
Sbjct: 2508 PPQPQPPPPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQ-----------PQTQPQPV 2556
Query: 1924 QSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGP-AGTMVPPSYSSQPYQSTHPSTNP 1982
Q+ ++ G T S G TG +G ++ + + P +T S N
Sbjct: 2557 QAPAKAQPAITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIVNTIAGVP-AATFQSINK 2615
Query: 1983 TLVDP------TRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQ 2036
L P T P+ VH Q P G +T ++ T + +T ++A
Sbjct: 2616 RLASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTAS 2675
Query: 2037 GVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQ 2096
V +T + P Q + Q Q Q + H Q+LRQQQQQQQ
Sbjct: 2676 AVV----TTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHF------QLLRQQQQQQQ 2725
Query: 2097 QQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVR 2156
Q QQQQQQ QQQQQQQ QQ QQQQ T
Sbjct: 2726 Q------------QQQQQQQQQQQQQQ-------------------QQQQQQQTTTTSQV 2754
Query: 2157 QLQQQLSNTQPQPSTNIFGR 2176
Q+ Q Q G+
Sbjct: 2755 QVPQIQGQAQSPAQIKAVGK 2774
Score = 53.9 bits (128), Expect = 2e-06
Identities = 124/517 (23%), Positives = 167/517 (32%), Gaps = 104/517 (20%)
Query: 1741 PLPLPPEDEEPPAPTLLEPEKKAPEPPKTDKPGAAPPSTE---ERKKKSTKGKKRSQPAT 1797
P P PP + P P L +P+ +PP P A P + + + + + ++QPA
Sbjct: 2509 PQPQPPPPPQQPPPPLPQPQAAGSQPPAG--PPAVQPQPQPQPQTQPQPVQAPAKAQPAI 2566
Query: 1798 KTEDYGMG---------PGRSGPYGVT-----------VPPDLLHHPN--------PGSI 1829
T G S P G VP N PG++
Sbjct: 2567 TTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGAL 2626
Query: 1830 THLNYRQGSIGLYTQNQPLPAGGPRVDPYRPVRL-----------------------PMQ 1866
T + ++TQ P G P V + P+Q
Sbjct: 2627 TTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPVQ 2686
Query: 1867 KLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSS 1926
P R P V T + G + + RQQQ Q Q+ +QQ QQ Q Q
Sbjct: 2687 T-PARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQ 2745
Query: 1927 VHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQ-PYQSTHPSTNPTLV 1985
Q T +S + QG + + P + Q P Q P
Sbjct: 2746 -QQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPP 2804
Query: 1986 DPTRHLQQRPSGYVHQQ--------APTYGHGLTSTQ----------RFSHQTLQQTPMI 2027
PT +Q + S QQ AP G LT T R LQ +
Sbjct: 2805 QPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRVPTSQLQAQGQM 2864
Query: 2028 STMTPMSAQGVQAG----------VRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQY 2077
T P AQ A V S + Q Q+ Q Q
Sbjct: 2865 QTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQTVVAQPV 2924
Query: 2078 HIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQ------QQQQAAPPQPQP 2131
H+ QQ + +QQ QQQ+ Q Q Q QQ+ QQ QQ+ A QP
Sbjct: 2925 HM----QQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPAL 2980
Query: 2132 QSQ----PQFQRQ---GLQQTQQQQQTAALVRQLQQQ 2161
++Q P Q Q G QQ Q Q Q A L + +QQQ
Sbjct: 2981 KTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQ 3017
Score = 37.0 bits (84), Expect = 0.21
Identities = 61/300 (20%), Positives = 116/300 (38%), Gaps = 36/300 (12%)
Query: 1843 TQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMG-------LEPSSYKT 1895
+Q Q P+ GP V + P+ +LP R GV ++ + +E +
Sbjct: 531 SQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQFAQQPQVVEAQTQLQ 590
Query: 1896 SVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQ--GYTPYVSHVGL 1953
+ QQP VP QL Q ++H TP +Q SQ V+ L
Sbjct: 591 IPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHVPTP-GKVQVQASQLSSLPQMVASTRL 649
Query: 1954 QQHTGPAGTMVPPSYSSQ---PYQSTHPSTNPTLVDPTRH-----------LQQRPSGYV 1999
P P+ S+ P + P +P P + R G V
Sbjct: 650 PVDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPARSSPVNRPSSATNKALSPVTSRTPGVV 709
Query: 2000 HQQAPTY----GHGLTSTQRFSHQTL-QQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQ 2054
APT TS+Q S TL +Q + + + A+ +AG+ S LP+ Q+
Sbjct: 710 -ASAPTKPQSPAQNATSSQDSSQDTLTEQITLENQVHQRIAELRKAGLWSQRRLPKLQEA 768
Query: 2055 QQQQQ------QQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQ 2108
+ + ++ Q Q+++ + ++ + ++R +++Q ++++ ++++Q +
Sbjct: 769 PRPKSHWDYLLEEMQWMATDFAQERRWKVAAAKKLVRTVVRHHEEKQLREERGKKEEQSR 828
Score = 36.2 bits (82), Expect = 0.36
Identities = 27/77 (35%), Positives = 35/77 (45%), Gaps = 9/77 (11%)
Query: 2082 QQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAA-------PP--QPQPQ 2132
++++ + QQ+ QQ Q Q Q QQ Q QAA PP QPQPQ
Sbjct: 2487 KEKKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQ 2546
Query: 2133 SQPQFQRQGLQQTQQQQ 2149
QPQ Q Q +Q + Q
Sbjct: 2547 PQPQTQPQPVQAPAKAQ 2563
Score = 33.5 bits (75), Expect = 2.3
Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 4/84 (4%)
Query: 2086 QILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQT 2145
Q+ + ++ ++++ QQ+ QQ Q Q Q PPQ P PQ Q G
Sbjct: 2476 QVASLRAERIAKEKKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAG---- 2531
Query: 2146 QQQQQTAALVRQLQQQLSNTQPQP 2169
Q V+ Q TQPQP
Sbjct: 2532 SQPPAGPPAVQPQPQPQPQTQPQP 2555
>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
Length = 1424
Score = 85.5 bits (210), Expect = 5e-16
Identities = 77/235 (32%), Positives = 102/235 (43%), Gaps = 46/235 (19%)
Query: 1907 QGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPP 1966
QGQ + Q G+ GQ+ Q P G QG +P + + Q +
Sbjct: 1096 QGQEAAVMMDQKAGLYGQTYPAQGPPMQ--GGFHLQGQSPSFNSMMNQMN---------- 1143
Query: 1967 SYSSQPYQSTHPSTN---PTLVDPTR---HLQQRPSGYVHQQAPTYGHGLTSTQRFSHQT 2020
+ P Q HP N P P + LQQR G Q+F +Q+
Sbjct: 1144 QQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQG----------------QQFLNQS 1187
Query: 2021 LQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIR 2080
Q + M +A G + + P Q Q QQ Q Q+ ++ +H R
Sbjct: 1188 RQALEL--KMENPTAGG------AAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLSHHFR 1239
Query: 2081 QQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQP 2135
QQ+ +++QQQQQQQQQQQQQQQQQQQQQQQ QQQQQ QA P P + P
Sbjct: 1240 QQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQ----QQQQQTQAFSPPPNVTASP 1290
Score = 57.4 bits (137), Expect = 2e-07
Identities = 97/427 (22%), Positives = 156/427 (36%), Gaps = 38/427 (8%)
Query: 1764 PEPPKTDKPGAAPP--STEERKKKSTKGKKRSQPATKTEDYGMGPGRSGPYGVTVPPDLL 1821
P PK G P ++E S G R+ T+T G + G P +
Sbjct: 877 PMLPKQPMLGGNPRMMDSQENYGSSMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSN 936
Query: 1822 HHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTT 1881
PG + + + ++G PL + + RPV Q++ PG +P
Sbjct: 937 SMGRPGGDYNTSLPRPALGGSIPTLPLRSNS--IPGARPVLQQQQQM--LQMRPGEIP-- 990
Query: 1882 MTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQ---QSQGMLGQSSVHQMTPSSSYGL 1938
MG+ + Y + Q + P G +Q+ Q++ +L S + P S+
Sbjct: 991 ----MGMGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEG 1046
Query: 1939 QTSQGYTPYVSHVGLQQHTGPAG------TMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQ 1992
Q+ + H L +T G + P +Q Q+ P + +
Sbjct: 1047 QSDERALLDQLHT-LLSNTDATGLEEIDRALGIPELVNQG-QALEPKQDAFQGQEAAVMM 1104
Query: 1993 QRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMT-----PMSAQGVQAGV-RSTA 2046
+ +G Q P G + Q+ M++ M P+ +A + R
Sbjct: 1105 DQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRT 1164
Query: 2047 ILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQ---QQQ 2103
P+Q + Q QQ+ Q QQ Q +Q + + ++R Q Q QQ Q
Sbjct: 1165 NTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQVSSQQGFLNAQ 1224
Query: 2104 QQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLS 2163
Q+ ++ H +QQ+ Q Q Q Q Q Q+Q QQ QQQQQ Q QQQ
Sbjct: 1225 MVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQ------QQQQQTQ 1278
Query: 2164 NTQPQPS 2170
P P+
Sbjct: 1279 AFSPPPN 1285
Score = 33.9 bits (76), Expect = 1.8
Identities = 42/166 (25%), Positives = 64/166 (38%), Gaps = 24/166 (14%)
Query: 1899 RQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSY-GL-------QTSQGYTPYVSH 1950
+QQQ Q Q+ +QQ QQ Q S +T S S GL Q PY +
Sbjct: 1255 QQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPN 1314
Query: 1951 VGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDP-------TRHLQQRPSGYVHQQA 2003
G+ Q PA V ++ PS NP + P + ++ PSG + + +
Sbjct: 1315 YGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARNS 1374
Query: 2004 PTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILP 2049
S Q+F+H Q P + +M M+ G + +P
Sbjct: 1375 S------FSQQQFAH---QGNPAVYSMVHMNGSSGHMGQMNMNPMP 1411
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 82.4 bits (202), Expect = 4e-15
Identities = 99/340 (29%), Positives = 124/340 (36%), Gaps = 95/340 (27%)
Query: 1844 QNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQP 1903
QN P+PA P +P + +K + +PTT +TS+ +Q+P
Sbjct: 325 QNSPIPAKLP--EPVKASEAAAKKTQPKARLTDPIPTT------------ETSIAPRQRP 370
Query: 1904 AVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTM 1963
Q Q + G+L +TP +Q + GL
Sbjct: 371 KAGQ-------TQPNPGILPIQPA--LTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQ 421
Query: 1964 VPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQ 2023
PPS Q+ P PT QQ PS T GL + + + Q QQ
Sbjct: 422 APPSQPLPQTQAKQPQAPPTP-------QQTPS--------TQAQGLPAQAQATPQHQQQ 466
Query: 2024 TPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQ-----QQQQQQQQQQQQYH 2078
L +QQQQQQ QQQ QQQQ Q QQ Q H
Sbjct: 467 L----------------------FLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVH 504
Query: 2079 IRQQQ--------------QQQILRQQQQQQQQQQQQQQQQQ-----QQQQQQQQQ---- 2115
QQ QQQ+++ QQQQQQQQQQQQQQ QQQ QQ
Sbjct: 505 PATQQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQ 564
Query: 2116 -------HQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQ 2148
QQ Q Q AA PQP P +P Q QQ + Q
Sbjct: 565 QKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQPKVQ 604
Score = 68.9 bits (167), Expect = 5e-11
Identities = 74/231 (32%), Positives = 84/231 (36%), Gaps = 23/231 (9%)
Query: 1959 PAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHL----QQRPSGYVHQQAP---TYGHGLT 2011
PA P S + T P T PT +QRP Q P LT
Sbjct: 330 PAKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALT 389
Query: 2012 STQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQ 2071
+R + Q Q S + A Q ++ P Q Q +Q Q QQ Q
Sbjct: 390 PRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQ 449
Query: 2072 QQ---QQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQ 2128
Q Q Q QQQ L+QQQQQQQ QQQ QQQQ Q QQ Q A Q
Sbjct: 450 AQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQ 509
Query: 2129 P-------------QPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQ 2166
P Q Q F +Q QQ QQQQQ QQQL Q
Sbjct: 510 PAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQ 560
Score = 64.3 bits (155), Expect = 1e-09
Identities = 61/172 (35%), Positives = 66/172 (38%), Gaps = 50/172 (29%)
Query: 2049 PEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQ-----------ILRQQQQQQQQ 2097
P QQ Q Q Q Q Q QQQ ++QQQQQQ QQQQ Q Q
Sbjct: 439 PPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQ 498
Query: 2098 Q------------------------QQQ------QQQQQQQQQQQQQQ-----HQQQQQQ 2122
Q QQQ QQQQQQQQQQQQQQ HQQQ
Sbjct: 499 QFQAVHPATQQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMT 558
Query: 2123 QAAPPQPQPQ----SQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPS 2170
Q A Q +P QPQ Q Q Q+ A QQ T P P+
Sbjct: 559 QQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQPKVQTTPPPA 610
Score = 43.5 bits (101), Expect = 0.002
Identities = 50/196 (25%), Positives = 65/196 (33%), Gaps = 12/196 (6%)
Query: 1966 PSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTP 2025
P+ + P + P P + +P + PT + QR Q P
Sbjct: 322 PNVQNSPIPAKLPE--PVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNP 379
Query: 2026 MISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQ- 2084
I + P +A V+ Q Q + Q Q Q +Q Q
Sbjct: 380 GILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAP 439
Query: 2085 ---QQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQG 2141
QQ Q Q Q Q Q QQQ +QQQ QQQ PP Q Q F +Q
Sbjct: 440 PTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQ------PPPAQQQPAGTFYQQQ 493
Query: 2142 LQQTQQQQQTAALVRQ 2157
QTQQ Q +Q
Sbjct: 494 QAQTQQFQAVHPATQQ 509
Score = 38.5 bits (88), Expect = 0.073
Identities = 40/148 (27%), Positives = 56/148 (37%), Gaps = 7/148 (4%)
Query: 2034 SAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQ 2093
+A+ Q R T +P + +Q+ + Q Q Q + +++ + Q
Sbjct: 343 AAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQA 402
Query: 2094 QQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQ--PQPQSQPQFQRQGL----QQTQQ 2147
Q Q + Q Q Q QA PQ P PQ P Q QGL Q T Q
Sbjct: 403 AGSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQ 462
Query: 2148 QQQTAALVRQLQQQLSN-TQPQPSTNIF 2174
QQ L +Q QQQ Q QP+ +
Sbjct: 463 HQQQLFLKQQQQQQQPPPAQQQPAGTFY 490
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 80.9 bits (198), Expect = 1e-14
Identities = 110/468 (23%), Positives = 189/468 (40%), Gaps = 68/468 (14%)
Query: 1725 LYHTHLRPRPRAYYLEPLPLPP----EDEEPPAPTL--LEPEKKAPEPPKTDKPGAAPPS 1778
L T L P+P P+ PP EDEEPPAP L ++ + + K P PS
Sbjct: 894 LTQTPLLPQP------PMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPS 947
Query: 1779 TEERKKKSTKGKKRSQPATKTEDYGMGPGRSGPYGVTVPPDLLHHPNPGSITHLNYRQGS 1838
+ + + P+ + + P P PP H P P + HL Q S
Sbjct: 948 VKVQSQPPPPLPPPPHPSVQ-QQLQQQPPPPPPPQPQPPPQQQHQPPPRPV-HLQPMQFS 1005
Query: 1839 IGLYTQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVY 1898
+ Q P P G + P+ P Q P +P P + + Y T
Sbjct: 1006 T--HIQQPPPPQG--QQPPHPPPG--QQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHL 1059
Query: 1899 RQ-------QQPAVPQGQRL------RQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYT 1945
R+ P + Q Q L +Q +Q + L +SV Q P ++ + ++
Sbjct: 1060 REAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQ--PQPLVVVKEEKIHS 1117
Query: 1946 PYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPT 2005
P + P P S + + P P VD R + + P Q AP
Sbjct: 1118 PIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKP--VDVGRPVIRPPE----QNAPP 1171
Query: 2006 YGHGLTSTQRFSHQT-------------------LQQTPMISTMTPMSAQGVQAGVRSTA 2046
G Q+ +T +Q+ P + T S+ R A
Sbjct: 1172 PGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAA 1231
Query: 2047 ILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQ 2106
++++++++ + Q + ++++++ +Q +R ++ + L Q ++ ++ +++Q+QQQ
Sbjct: 1232 ----REKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQ 1287
Query: 2107 QQQQQQQQQHQQQQQQQAAPPQPQPQ-SQPQF---QRQGLQQTQQQQQ 2150
QQ+Q+QQQQ QQQ AA PQ Q SQPQ Q++ L + ++Q++
Sbjct: 1288 QQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQER 1335
Score = 63.9 bits (154), Expect = 2e-09
Identities = 94/433 (21%), Positives = 159/433 (36%), Gaps = 86/433 (19%)
Query: 1731 RPRPRAYYLEPLPLPPEDEEPPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGK 1790
+P PR +L+P+ ++PP P +P P PP PG PP + K +
Sbjct: 991 QPPPRPVHLQPMQFSTHIQQPPPPQGQQP----PHPP----PGQQPPPPQPAKPQQVIQH 1042
Query: 1791 KRSQPATKTEDYGMGPGRSGPYGVTVPPDLLHHPNPG---SITHLNYRQGSIGLYTQNQP 1847
S K++ Y G R P P ++H P S+TH + Q ++ + Q
Sbjct: 1043 HHSPRHHKSDPYSTGHLREAP-----SPLMIHSPQMSQFQSLTHQSPPQQNV--QPKKQE 1095
Query: 1848 LPAGGPRVDPYRPVRLPMQKLPT-----RPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQ 1902
L A V P V + +K+ + P P + P P S K V+ Q+
Sbjct: 1096 LRAASV-VQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPK-----HPESIKAPVHLPQR 1149
Query: 1903 PAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGT 1962
P +M P VG P
Sbjct: 1150 P-------------------------EMKPVD----------------VGRPVIRPPEQN 1168
Query: 1963 MVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQ 2022
PP + Q P T V P + L+ + G + +ST + S + +
Sbjct: 1169 APPPGAPDKDKQKQEPKTP---VAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFE 1225
Query: 2023 QTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQ 2082
Q + + ++A A +++ +Q++ + ++ + +Q ++ ++ RQ+
Sbjct: 1226 QFRRAAREKEEREKALKAQAEH-AEKEKERLRQERMRSREDEDALEQARRAHEEARRRQE 1284
Query: 2083 QQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGL 2142
QQQQ Q+Q+QQQQQQQQ Q Q Q PQ Q + R+
Sbjct: 1285 QQQQ---QRQEQQQQQQQQAAAVAAAATPQAQSSQ---------PQSMLDQQRELARKRE 1332
Query: 2143 QQTQQQQQTAALV 2155
Q+ ++++ AA +
Sbjct: 1333 QERRRREAMAATI 1345
Score = 62.0 bits (149), Expect = 6e-09
Identities = 99/426 (23%), Positives = 140/426 (32%), Gaps = 67/426 (15%)
Query: 1720 QQRLLLYHTHLRPRPRAYYLEPLPLPPEDEEPPAPTLLEPEKKAPEPPKTDKPGAAPPST 1779
+Q+ +H H + + + P PP + PP P + ++ P PP P A P+
Sbjct: 734 EQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAM 793
Query: 1780 EERKKKSTKGKKRSQPATKTEDYGMGPGRSG----PYGVTVPPDLLHHPNPGSITHLNYR 1835
K P T+ + P G P G P +LH P P HL
Sbjct: 794 ----------KSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQP-ILHLPQPELPPHLPQP 842
Query: 1836 QGSIGLYTQNQPLPAGGPRVD---PYRPVRLPMQK---LPTRPTY-PGVLPT-TMTGVMG 1887
NQ P + P +P R P + LP +P P V P T T ++
Sbjct: 843 PEHSTPPHLNQHAVVSPPALHNALPQQPSR-PSNRAAALPPKPARPPAVSPALTQTPLLP 901
Query: 1888 LEPSSYKTSV-YRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTP 1946
P + V ++P P ++ QL Q LQ Q TP
Sbjct: 902 QPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQ------------------LQKVQPPTP 943
Query: 1947 YVSHVGLQQHTGPAGTMVP-PSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPT 2005
+ V +Q P P PS Q Q P P P + Q P VH Q
Sbjct: 944 LLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQ--- 1000
Query: 2006 YGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQ 2065
+FS Q P P G Q P Q + QQ Q
Sbjct: 1001 -------PMQFSTHIQQPPPPQGQQPPHPPPGQQP--------PPPQPAKPQQVIQHHHS 1045
Query: 2066 QQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAA 2125
+ + H+R+ ++ Q Q Q Q QQ Q ++Q+ + A+
Sbjct: 1046 PRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQP-----KKQELRAAS 1100
Query: 2126 PPQPQP 2131
QPQP
Sbjct: 1101 VVQPQP 1106
Score = 50.1 bits (118), Expect = 2e-05
Identities = 94/494 (19%), Positives = 177/494 (35%), Gaps = 103/494 (20%)
Query: 1731 RPRPRAYYLEPLPLPPEDEEPP-APTLLEPEKKAPEPPKT---DKPGAAPPSTEERKKKS 1786
RP RA L P P P P T L P+ +PP+ D+ APP T + +
Sbjct: 872 RPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLY 931
Query: 1787 TKGKKRSQPATKTEDYGMGPGRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIGLYTQNQ 1846
+ ++ QP T S PP L P+P S+ Q Q
Sbjct: 932 LQQLQKVQPPTPLLP-------SVKVQSQPPPPLPPPPHP-----------SVQQQLQQQ 973
Query: 1847 PLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVP 1906
P P P+ P P Q+ P P + L+P + T + QQP P
Sbjct: 974 PPPPPPPQPQP------PPQQQHQPPPRP----------VHLQPMQFSTHI---QQPPPP 1014
Query: 1907 QGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPP 1966
QGQ+ Q Q + Q + + + H+ P+ M+
Sbjct: 1015 QGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHL----REAPSPLMIHS 1070
Query: 1967 SYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPM 2026
SQ TH S V P + Q+ + V Q P + ++ ++ P
Sbjct: 1071 PQMSQFQSLTHQSPPQQNVQPKK--QELRAASVVQPQPLV---VVKEEKIHSPIIRSEPF 1125
Query: 2027 ISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQ-------------------QQQQQQQQQ 2067
++ P + ++ +++ LP++ + + + +Q+Q+
Sbjct: 1126 SPSLRPEPPKHPES-IKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEP 1184
Query: 2068 QQQQQQQQQYHIRQ--------------------------QQQQQILRQQQQQQQQQQQQ 2101
+ ++ I+ +Q ++ R+++++++ + Q
Sbjct: 1185 KTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQ 1244
Query: 2102 QQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQ-------TQQQQQTAAL 2154
+ ++++++ +Q+ + ++ + A Q + + +RQ QQ QQQQQ AA+
Sbjct: 1245 AEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAV 1304
Query: 2155 VRQLQQQLSNTQPQ 2168
Q ++QPQ
Sbjct: 1305 AAAATPQAQSSQPQ 1318
Score = 45.8 bits (107), Expect = 5e-04
Identities = 79/357 (22%), Positives = 113/357 (31%), Gaps = 53/357 (14%)
Query: 1842 YTQNQPLPAGGPRVDPYRPVRLP------MQKLPTRPTYPGVLPTTMTGVMGLEPSSYKT 1895
+ Q Q PA P+ P P + P Q+ P P P +P M P +
Sbjct: 743 HQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIA 802
Query: 1896 SVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGL-QTSQGYTPYVSHVGLQ 1954
+ +P +P + G Q +H P L Q + TP
Sbjct: 803 TQVPVLEPQLPGS------VFDPIGHFTQPILHLPQPELPPHLPQPPEHSTP-------- 848
Query: 1955 QHTGPAGTMVPPS-YSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTST 2013
H + PP+ +++ P Q + PS + P +P+ + P LT T
Sbjct: 849 PHLNQHAVVSPPALHNALPQQPSRPSNRAAALPP------KPA-----RPPAVSPALTQT 897
Query: 2014 QRFSHQTLQQTPMI-------------STMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQ 2060
+ Q P + S + Q +Q T +LP + Q Q
Sbjct: 898 PLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPP 957
Query: 2061 QQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQ 2120
QQQ QQQ Q Q QQQ Q + Q Q QQ Q Q
Sbjct: 958 LPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQ 1017
Query: 2121 Q-------QQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPS 2170
Q QQ PPQP Q + + + +R+ L PQ S
Sbjct: 1018 QPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMS 1074
Score = 40.4 bits (93), Expect = 0.019
Identities = 23/87 (26%), Positives = 36/87 (41%), Gaps = 1/87 (1%)
Query: 2050 EQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQ 2109
E + + + + + + +++ H ++Q++ QQ QQ QQ
Sbjct: 702 ESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPP 761
Query: 2110 QQQQQQHQQQQQQQAAPPQPQPQSQPQ 2136
QQ QQQQQ PP P P S PQ
Sbjct: 762 QQPPPPPPPQQQQQP-PPPPPPPSMPQ 787
Score = 34.3 bits (77), Expect = 1.4
Identities = 17/61 (27%), Positives = 28/61 (45%)
Query: 2090 QQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQ 2149
+ + + + +++ ++Q++ H QQ QQA P PQ P Q QQQQ
Sbjct: 715 EDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQ 774
Query: 2150 Q 2150
Q
Sbjct: 775 Q 775
Score = 32.0 bits (71), Expect = 6.8
Identities = 30/135 (22%), Positives = 46/135 (34%), Gaps = 42/135 (31%)
Query: 1741 PLPLPPEDEEPPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGKKRSQPATKTE 1800
P P+PP+ + PPAP AP+P ++ P A + KK K K + T +
Sbjct: 250 PPPVPPQPQPPPAP--------APQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTID 301
Query: 1801 DYGMGPGRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRP 1860
+ PP L P + G R + RP
Sbjct: 302 P------------IHEPPSLPPEPKTTKL----------------------GQRRESSRP 327
Query: 1861 VRLPMQKLPTRPTYP 1875
V+ P + +P +P
Sbjct: 328 VKPPKKDVPDSQQHP 342
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 80.5 bits (197), Expect = 2e-14
Identities = 127/470 (27%), Positives = 164/470 (34%), Gaps = 90/470 (19%)
Query: 1743 PLPPEDEEPPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKS--TKGKKRSQPATKTE 1800
P P ++P P +P + P+ P + PP + ++GK Q T
Sbjct: 1855 PTTPTGQQPTTPQTPQPTSQ----PQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTP 1910
Query: 1801 DYGMGPGRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRP 1860
P GP PP + RQ + Q +P+ P + P P
Sbjct: 1911 PQTAQPPLPGP-----PPAAVEMAMQIQRAAETQRQMAHVQIFQ-RPIQHQMPPMTPMAP 1964
Query: 1861 VRL---PMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLR-QQLQ 1916
+ + PM + P+ PG+ PT M QQQP QG + QQLQ
Sbjct: 1965 MGMNPPPMTRGPSGHLEPGMGPTGM-----------------QQQPPWSQGGLPQPQQLQ 2007
Query: 1917 QSQGMLGQSSVHQ------MTPSSSYGLQTSQGYTP-YVSHVGLQQHTGPAGTMVPPSYS 1969
SV Q M P G P VS LQ + P
Sbjct: 2008 SGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQ 2067
Query: 1970 SQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQA---------PTYGHGLTSTQRFSHQT 2020
Q H NP L+ ++QR + Y + P GL Q
Sbjct: 2068 QQVLSILH--ANPQLL--AAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQG 2123
Query: 2021 LQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIR 2080
+ P + M PM QAGV+ + QQQ QQQ Q Q QQ ++
Sbjct: 2124 VHSNPAMQNMNPM-----QAGVQRAGL---PQQQPQQQLQPPMGGMSPQAQQMNMNHNTM 2175
Query: 2081 QQQQQQILRQQQQQQQQQQQ------------QQQQQQQQ------QQQQQQQHQQQQQQ 2122
Q + ILR+QQ QQQQQQ Q QQ Q QQQQ+ QH QQ Q
Sbjct: 2176 PSQFRDILRRQQMMQQQQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQ 2235
Query: 2123 QAAPPQ--PQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQL-SNTQPQP 2169
Q Q PQ+ LQ QQ R LQQQ+ S QP P
Sbjct: 2236 QGNMGQIGQLPQALGAEAGASLQAYQQ--------RLLQQQMGSPVQPNP 2277
Score = 54.7 bits (130), Expect = 1e-06
Identities = 94/453 (20%), Positives = 145/453 (32%), Gaps = 70/453 (15%)
Query: 1708 VRVDRRVARGEEQQRLLLYHTHLRPRPRAYYLEPLPLPPEDEEPPAPTLLEPEKKAPEPP 1767
V + ++ R E QR + H + RP + + P+ P AP + P P
Sbjct: 1926 VEMAMQIQRAAETQRQMA-HVQIFQRPIQHQMPPMT-------PMAPMGMNPPPMTRGPS 1977
Query: 1768 KTDKPGAAPPSTEERKKKSTKG-------------------KKRSQPATKTEDYGMG--- 1805
+PG P +++ S G + QP G+G
Sbjct: 1978 GHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVG 2037
Query: 1806 --PGRSGPYGVTVPPDLLHH-PNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRPVR 1862
P + G +LL +P S +Q + + N L A + +
Sbjct: 2038 ISPLKPGTVSQQALQNLLRTLRSPSSPLQ---QQQVLSILHANPQLLAAFIKQRAAKYAN 2094
Query: 1863 LPMQKLPTRPTYP----GVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQS 1918
Q +P +P P G+ P TM G G+ + ++ Q G +Q QQ
Sbjct: 2095 SNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQL 2154
Query: 1919 QGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHP 1978
Q +G S + ++ SQ +QQ Q Q P
Sbjct: 2155 QPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQ---------------QQQQGAGP 2199
Query: 1979 STNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGV 2038
P + + + Q + GY QQ H + Q+ + + Q P A G
Sbjct: 2200 GIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQ--------ALGA 2251
Query: 2039 QAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQ 2098
+AG Q QQ+ QQQ Q QQ+ + Q Q L+ QQ
Sbjct: 2252 EAGA-------SLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLS 2304
Query: 2099 QQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQP 2131
Q + Q + Q Q PQP P
Sbjct: 2305 NQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSP 2337
Score = 37.0 bits (84), Expect = 0.21
Identities = 59/260 (22%), Positives = 94/260 (36%), Gaps = 14/260 (5%)
Query: 1826 PGSI-THLNYRQGSIGLYTQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTG 1884
PGS +H++ Q QN P P P+ + P T P +PT
Sbjct: 810 PGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAM 869
Query: 1885 VMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGY 1944
G P S +Q P P Q L QQ+Q S + Q P S S
Sbjct: 870 PPG--PQSQALHPPPRQTPTPPTTQ-LPQQVQPSLPAAPSADQPQQQPRSQQSTAASVP- 925
Query: 1945 TPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAP 2004
TP + Q PA + P+ S + S PST+ T V+ +++PS V +A
Sbjct: 926 TPTAPLLPPQ----PATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAK 981
Query: 2005 TYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQ 2064
+ Q T + S + + + RST + E ++++ Q Q
Sbjct: 982 -----MEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQ 1036
Query: 2065 QQQQQQQQQQQQYHIRQQQQ 2084
Q +++ + + +Q
Sbjct: 1037 SSPAPGQSKKKIFKPEELRQ 1056
Score = 34.7 bits (78), Expect = 1.0
Identities = 80/348 (22%), Positives = 113/348 (32%), Gaps = 56/348 (16%)
Query: 1875 PGVLPTTMTGVMGLEPSSYKT-SVYRQQQPAVPQGQRLRQQLQQSQGMLGQS-SVHQMTP 1932
P P T T G +P++ +T Q QP P Q+ G + Q + Q+TP
Sbjct: 1848 PSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTP 1907
Query: 1933 SSSYGLQTSQGYTP---------------------YVSHVGLQQHTGPAGTMVPPSYSSQ 1971
+ QT+Q P ++HV + Q P +PP
Sbjct: 1908 PTPP--QTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQR--PIQHQMPPMTPMA 1963
Query: 1972 PYQSTHPSTNPTLVDPTRHLQ--QRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMIST 2029
P P P P+ HL+ P+G + QQ P GL Q+ + + M+S
Sbjct: 1964 PMGMNPP---PMTRGPSGHLEPGMGPTG-MQQQPPWSQGGLPQPQQLQ-SGMPRPAMMSV 2018
Query: 2030 MT---PMSAQGVQAGVRSTAILP------EQQQQQQQQQQQQQQQQQQQQQQQQQQYHIR 2080
P++ Q G+ I P QQ Q + + QQQQ H
Sbjct: 2019 AQHGQPLN-MAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHAN 2077
Query: 2081 QQQQQQILRQQQQ------------QQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQ 2128
Q ++Q+ Q Q Q Q QQ H Q P Q
Sbjct: 2078 PQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQ 2137
Query: 2129 PQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPSTNIFGR 2176
Q Q+Q QQ Q + Q NT P +I R
Sbjct: 2138 AGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRR 2185
Score = 32.7 bits (73), Expect = 4.0
Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 26/86 (30%)
Query: 2077 YHIRQQQQQQI-------LRQQQQQQQQQQQQQQQQQQQQQQQQQQHQ----QQQ----- 2120
YH + Q+ + ++Q+ +QQQ Q + QQ Q +++ Q QQQ
Sbjct: 1791 YHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSP 1850
Query: 2121 ----------QQQAAPPQPQPQSQPQ 2136
QQ P PQP SQPQ
Sbjct: 1851 TPATPTTPTGQQPTTPQTPQPTSQPQ 1876
Score = 32.7 bits (73), Expect = 4.0
Identities = 24/91 (26%), Positives = 36/91 (39%), Gaps = 6/91 (6%)
Query: 2051 QQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQ 2110
+Q+ +QQQ Q + QQ Q +++ + Q+ ++ QQQ QQ
Sbjct: 1810 KQKLRQQQLQHRLQQAQMLRRR------MASMQRTGVVGQQQGLPSPTPATPTTPTGQQP 1863
Query: 2111 QQQQQHQQQQQQQAAPPQPQPQSQPQFQRQG 2141
Q Q Q Q PP P P+ Q G
Sbjct: 1864 TTPQTPQPTSQPQPTPPNSMPPYLPRTQAAG 1894
Score = 31.6 bits (70), Expect = 8.9
Identities = 73/330 (22%), Positives = 106/330 (32%), Gaps = 43/330 (13%)
Query: 1862 RLPMQKLPTRPTYPGVLPTTMTGVMGL-EPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQG 1920
R +QK P G++P +M + +P TS P++ +G Q + +
Sbjct: 649 RTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPR--- 705
Query: 1921 MLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPST 1980
+ QS ++Q S TP + H G Q P P Y + Q PS
Sbjct: 706 ITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHG--QLAQPGALNPPMGYGPRMQQ---PSN 760
Query: 1981 NPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQA 2040
+ T+ Q + AP+ G S Q M S+ P+++ +
Sbjct: 761 QGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVS----------QAQMSSSSCPVNSPIMPP 810
Query: 2041 GVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQIL---------RQQ 2091
G + + I Q Q Q + I QQ
Sbjct: 811 GSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMP 870
Query: 2092 QQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQT 2151
Q Q +Q Q Q Q AAP QPQ QP + QQ T
Sbjct: 871 PGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQP----------RSQQST 920
Query: 2152 AALVRQLQQQLSNTQP-----QPSTNIFGR 2176
AA V L QP QP+ +I G+
Sbjct: 921 AASVPTPTAPLLPPQPATPLSQPAVSIEGQ 950
>gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]
Length = 1420
Score = 80.1 bits (196), Expect = 2e-14
Identities = 75/235 (31%), Positives = 98/235 (41%), Gaps = 50/235 (21%)
Query: 1907 QGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPP 1966
QGQ + Q G+ GQ+ Q P G QG +P + + Q +
Sbjct: 1096 QGQEAAVMMDQKAGLYGQTYPAQGPPMQ--GGFHLQGQSPSFNSMMNQMN---------- 1143
Query: 1967 SYSSQPYQSTHPSTN---PTLVDPTR---HLQQRPSGYVHQQAPTYGHGLTSTQRFSHQT 2020
+ P Q HP N P P + LQQR G Q+F +Q+
Sbjct: 1144 QQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQG----------------QQFLNQS 1187
Query: 2021 LQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIR 2080
Q + M +A G + Q QQ Q Q+ ++ +H R
Sbjct: 1188 RQALEL--KMENPTAGGAAV----------MRPMMQPQQGFLNAQMVAQRSRELLSHHFR 1235
Query: 2081 QQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQP 2135
QQ+ ++ QQQQQQQQQQQQQQQQQQQQQQQ QQQQQ QA P P + P
Sbjct: 1236 QQRVAMMM----QQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASP 1286
Score = 56.6 bits (135), Expect = 3e-07
Identities = 97/424 (22%), Positives = 157/424 (37%), Gaps = 36/424 (8%)
Query: 1764 PEPPKTDKPGAAPP--STEERKKKSTKGKKRSQPATKTEDYGMGPGRSGPYGVTVPPDLL 1821
P PK G P ++E S G R+ T+T G + G P +
Sbjct: 877 PMLPKQPMLGGNPRMMDSQENYGSSMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSN 936
Query: 1822 HHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTT 1881
PG + + + ++G PL + + RPV Q++ PG +P
Sbjct: 937 SMGRPGGDYNTSLPRPALGGSIPTLPLRSNS--IPGARPVLQQQQQM--LQMRPGEIP-- 990
Query: 1882 MTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQ---QSQGMLGQSSVHQMTPSSSYGL 1938
MG+ + Y + Q + P G +Q+ Q++ +L S + P S+
Sbjct: 991 ----MGMGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEG 1046
Query: 1939 QTSQGYTPYVSHVGLQQHTGPAG------TMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQ 1992
Q+ + H L +T G + P +Q Q+ P + +
Sbjct: 1047 QSDERALLDQLHT-LLSNTDATGLEEIDRALGIPELVNQG-QALEPKQDAFQGQEAAVMM 1104
Query: 1993 QRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMT-----PMSAQGVQAGV-RSTA 2046
+ +G Q P G + Q+ M++ M P+ +A + R
Sbjct: 1105 DQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRT 1164
Query: 2047 ILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQ 2106
P+Q + Q QQ+ Q QQ Q +Q + + ++R Q QQ Q Q
Sbjct: 1165 NTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMVAQ 1224
Query: 2107 QQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQ 2166
+ ++ H +QQ+ A Q Q Q Q Q Q+Q QQ QQQQQ +Q QQQ
Sbjct: 1225 RSRELLS--HHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQ-----QQQQQQTQAFS 1277
Query: 2167 PQPS 2170
P P+
Sbjct: 1278 PPPN 1281
Score = 33.9 bits (76), Expect = 1.8
Identities = 42/166 (25%), Positives = 64/166 (38%), Gaps = 24/166 (14%)
Query: 1899 RQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSY-GL-------QTSQGYTPYVSH 1950
+QQQ Q Q+ +QQ QQ Q S +T S S GL Q PY +
Sbjct: 1251 QQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPN 1310
Query: 1951 VGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDP-------TRHLQQRPSGYVHQQA 2003
G+ Q PA V ++ PS NP + P + ++ PSG + + +
Sbjct: 1311 YGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARNS 1370
Query: 2004 PTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILP 2049
S Q+F+H Q P + +M M+ G + +P
Sbjct: 1371 S------FSQQQFAH---QGNPAVYSMVHMNGSSGHMGQMNMNPMP 1407
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 79.3 bits (194), Expect = 4e-14
Identities = 112/385 (29%), Positives = 133/385 (34%), Gaps = 62/385 (16%)
Query: 1805 GPGRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRPVRLP 1864
G G + G PP + S + R G++G P AGG P L
Sbjct: 240 GSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMG---GGGPSAAGGGTPQPTATPTL- 295
Query: 1865 MQKLPTRPT-------YPG--VLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQL 1915
+L T P+ YPG G G P+ + + A
Sbjct: 296 -NQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAA----- 349
Query: 1916 QQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQS 1975
S G +S M+P SS G TP S Q G M P QPY
Sbjct: 350 --SGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQM-----GKMRP-----QPYGG 397
Query: 1976 THPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSA 2035
T+P + Q PSG P GHG Q + QT Q+ PM SA
Sbjct: 398 TNPYSQQ---------QGPPSG------PQQGHGYPG-QPYGSQTPQRYPMTMQGRAQSA 441
Query: 2036 QGVQAGVRSTAILPEQQQQQQQ---QQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQ 2092
G G+ T +P QQ QQ Q QQ QQQQ QQ Q Q
Sbjct: 442 MG---GLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQP 498
Query: 2093 QQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQP--------QPQSQPQF-QRQGLQ 2143
QQQ Q Q Q Q Q QQ Q QQ+ P P PQSQP + Q Q
Sbjct: 499 SYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQS 558
Query: 2144 QTQQQQQTAALVRQLQQQLSNTQPQ 2168
QQQQ L QQ + QPQ
Sbjct: 559 PYQQQQPQQPAPSTLSQQAAYPQPQ 583
Score = 78.6 bits (192), Expect = 6e-14
Identities = 80/254 (31%), Positives = 91/254 (35%), Gaps = 13/254 (5%)
Query: 1918 SQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGP-AGTMVPPSYSSQPYQST 1976
S G GQ PSS PY Q GP +G Y QPY S
Sbjct: 366 SSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQ 425
Query: 1977 HPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTL---QQTPMISTMTPM 2033
P P + Y QQ P YG S QT QQ+P P
Sbjct: 426 TPQRYPMTMQGRAQSAMGGLSYT-QQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPP 484
Query: 2034 SAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQ 2093
+Q Q ++ P QQQ Q Q Q Q Q QQ Q H QQ Q
Sbjct: 485 YSQ--QPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPH-----QQSPAPYPSQ 537
Query: 2094 QQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQ-PQPQSQPQFQRQGLQQTQQQQQTA 2152
Q QQ Q Q Q Q Q +QQQQ QQ AP Q + PQ Q Q QQT QQ
Sbjct: 538 QSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRF 597
Query: 2153 ALVRQLQQQLSNTQ 2166
++L Q +Q
Sbjct: 598 PPPQELSQDSFGSQ 611
Score = 63.2 bits (152), Expect = 3e-09
Identities = 74/261 (28%), Positives = 90/261 (34%), Gaps = 19/261 (7%)
Query: 1899 RQQQPAVPQGQ--RLRQQ-------LQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVS 1949
R QP+ P Q ++R Q Q QG P YG QT Q Y +
Sbjct: 376 RTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQ 435
Query: 1950 HVGLQQHTGPAGTMVPPSYSSQ-PYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGH 2008
G + T P Y Q P P + H QQ+ Y Q H
Sbjct: 436 GRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPH 495
Query: 2009 GLTSTQRFSHQTLQQTPMI-STMTPMSAQGVQAG-VRSTAILPEQQQQQQQQQQQQ---- 2062
S Q+ Q Q P + S+ P S Q Q +S A P QQ QQ Q Q
Sbjct: 496 AQPSYQQ---QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYS 552
Query: 2063 QQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQ 2122
Q Q Q QQQQ Q QQ Q Q QQ QQ QQ+ Q+ Q Q
Sbjct: 553 QPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQA 612
Query: 2123 QAAPPQPQPQSQPQFQRQGLQ 2143
+AP + + LQ
Sbjct: 613 SSAPSMTSSKGGQEDMNLSLQ 633
Score = 52.8 bits (125), Expect = 4e-06
Identities = 75/311 (24%), Positives = 109/311 (35%), Gaps = 33/311 (10%)
Query: 1853 PRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLR 1912
P++ P P + P P ++M L+P + S Q P +P R
Sbjct: 1128 PKIQPPSPAGSGSMQGPQTPQSTS---SSMAEGGDLKPPT-PASTPHSQIPPLPGMSRSN 1183
Query: 1913 QQLQQSQGMLGQSSVHQ----MTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSY 1968
Q G S Q MTP+ Y Q S + + + + + P G+M +
Sbjct: 1184 SVGIQDAFNDGSDSTFQKRNSMTPNPGY--QPSMNTSDMMGRMSYEPNKDPYGSM-RKAP 1240
Query: 1969 SSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQ-QAPTYGHGLTSTQRFSHQTLQQTPMI 2027
S P+ S+ N + DP G V Y +G + + + +
Sbjct: 1241 GSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNM 1300
Query: 2028 STMTP---MSAQGVQAGVRSTAILPEQQQQQQQQQQQQ------------------QQQQ 2066
ST P + +G+ S + P QQQQQQQQ+ QQ
Sbjct: 1301 STGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTT 1360
Query: 2067 QQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAP 2126
QQQQQ + + R + + Q Q QQQQ Q Q QQQAA
Sbjct: 1361 MYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQ 1420
Query: 2127 PQPQPQSQPQF 2137
P PQ Q+
Sbjct: 1421 PSPQQDVYNQY 1431
Score = 33.9 bits (76), Expect = 1.8
Identities = 109/488 (22%), Positives = 152/488 (31%), Gaps = 86/488 (17%)
Query: 1715 ARGEEQQRLLLYHTHLRPRPRAYYLEPLPLPPEDEEP--------PAPTL-LEPEKKAPE 1765
A G QQR +H + P +PL P+ P P P P +
Sbjct: 349 ASGGAQQRS--HHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQG 406
Query: 1766 PPKTDKPGAAPPS------TEERKKKSTKGKKRSQPA-----TKTEDYGM-GPGRSGPYG 1813
PP + G P T +R + +G+ +S + YG GP G G
Sbjct: 407 PPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQG 466
Query: 1814 VTV-------------PPDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPY-- 1858
T PP P+ +Y+Q Q+QP P PY
Sbjct: 467 QTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQ-----QPQSQP-PQLQSSQPPYSQ 520
Query: 1859 RPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKT--SVYRQQQPAVPQGQRLRQQLQ 1916
+P + P Q+ P YP TT P S S Y+QQQP P L QQ
Sbjct: 521 QPSQPPHQQSPA--PYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAA 578
Query: 1917 QSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHT-GPAGTMVPPSYSSQPYQ- 1974
Q P S QT+ + L Q + G + P SS+ Q
Sbjct: 579 YPQ------------PQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQE 626
Query: 1975 ------STHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQ---------RFSHQ 2019
+ PS+ P L L G + T G++S+Q FS
Sbjct: 627 DMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVST--SGISSSQGEQSNPAQSPFSPH 684
Query: 2020 TLQQTPMI--STMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQY 2077
T P I + +P+ + A RS + P Q + Q Q
Sbjct: 685 TSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQS 744
Query: 2078 HIRQ-----QQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQ 2132
I Q Q+ Q+ + Q +Q Q +QQ P Q
Sbjct: 745 SIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYG 804
Query: 2133 SQPQFQRQ 2140
Q + RQ
Sbjct: 805 PQGGYPRQ 812
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 79.3 bits (194), Expect = 4e-14
Identities = 112/385 (29%), Positives = 133/385 (34%), Gaps = 62/385 (16%)
Query: 1805 GPGRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRPVRLP 1864
G G + G PP + S + R G++G P AGG P L
Sbjct: 240 GSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMG---GGGPSAAGGGTPQPTATPTL- 295
Query: 1865 MQKLPTRPT-------YPG--VLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQL 1915
+L T P+ YPG G G P+ + + A
Sbjct: 296 -NQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAA----- 349
Query: 1916 QQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQS 1975
S G +S M+P SS G TP S Q G M P QPY
Sbjct: 350 --SGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQM-----GKMRP-----QPYGG 397
Query: 1976 THPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSA 2035
T+P + Q PSG P GHG Q + QT Q+ PM SA
Sbjct: 398 TNPYSQQ---------QGPPSG------PQQGHGYPG-QPYGSQTPQRYPMTMQGRAQSA 441
Query: 2036 QGVQAGVRSTAILPEQQQQQQQ---QQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQ 2092
G G+ T +P QQ QQ Q QQ QQQQ QQ Q Q
Sbjct: 442 MG---GLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQP 498
Query: 2093 QQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQP--------QPQSQPQF-QRQGLQ 2143
QQQ Q Q Q Q Q QQ Q QQ+ P P PQSQP + Q Q
Sbjct: 499 SYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQS 558
Query: 2144 QTQQQQQTAALVRQLQQQLSNTQPQ 2168
QQQQ L QQ + QPQ
Sbjct: 559 PYQQQQPQQPAPSTLSQQAAYPQPQ 583
Score = 78.6 bits (192), Expect = 6e-14
Identities = 80/254 (31%), Positives = 91/254 (35%), Gaps = 13/254 (5%)
Query: 1918 SQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGP-AGTMVPPSYSSQPYQST 1976
S G GQ PSS PY Q GP +G Y QPY S
Sbjct: 366 SSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQ 425
Query: 1977 HPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTL---QQTPMISTMTPM 2033
P P + Y QQ P YG S QT QQ+P P
Sbjct: 426 TPQRYPMTMQGRAQSAMGGLSYT-QQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPP 484
Query: 2034 SAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQ 2093
+Q Q ++ P QQQ Q Q Q Q Q QQ Q H QQ Q
Sbjct: 485 YSQ--QPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPH-----QQSPAPYPSQ 537
Query: 2094 QQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQ-PQPQSQPQFQRQGLQQTQQQQQTA 2152
Q QQ Q Q Q Q Q +QQQQ QQ AP Q + PQ Q Q QQT QQ
Sbjct: 538 QSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRF 597
Query: 2153 ALVRQLQQQLSNTQ 2166
++L Q +Q
Sbjct: 598 PPPQELSQDSFGSQ 611
Score = 63.2 bits (152), Expect = 3e-09
Identities = 74/261 (28%), Positives = 90/261 (34%), Gaps = 19/261 (7%)
Query: 1899 RQQQPAVPQGQ--RLRQQ-------LQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVS 1949
R QP+ P Q ++R Q Q QG P YG QT Q Y +
Sbjct: 376 RTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQ 435
Query: 1950 HVGLQQHTGPAGTMVPPSYSSQ-PYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGH 2008
G + T P Y Q P P + H QQ+ Y Q H
Sbjct: 436 GRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPH 495
Query: 2009 GLTSTQRFSHQTLQQTPMI-STMTPMSAQGVQAG-VRSTAILPEQQQQQQQQQQQQ---- 2062
S Q+ Q Q P + S+ P S Q Q +S A P QQ QQ Q Q
Sbjct: 496 AQPSYQQ---QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYS 552
Query: 2063 QQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQ 2122
Q Q Q QQQQ Q QQ Q Q QQ QQ QQ+ Q+ Q Q
Sbjct: 553 QPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQA 612
Query: 2123 QAAPPQPQPQSQPQFQRQGLQ 2143
+AP + + LQ
Sbjct: 613 SSAPSMTSSKGGQEDMNLSLQ 633
Score = 40.8 bits (94), Expect = 0.015
Identities = 64/291 (21%), Positives = 100/291 (34%), Gaps = 16/291 (5%)
Query: 1853 PRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLR 1912
P++ P P + P P ++M L+P + S Q P +P R
Sbjct: 1128 PKIQPPSPAGSGSMQGPQTPQSTS---SSMAEGGDLKPPT-PASTPHSQIPPLPGMSRSN 1183
Query: 1913 QQLQQSQGMLGQSSVHQ----MTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSY 1968
Q G S Q MTP+ Y Q S + + + + + P G+M +
Sbjct: 1184 SVGIQDAFNDGSDSTFQKRNSMTPNPGY--QPSMNTSDMMGRMSYEPNKDPYGSM-RKAP 1240
Query: 1969 SSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQ-QAPTYGHGLTSTQRFSHQTLQQTPMI 2027
S P+ S+ N + DP G V Y +G + + + +
Sbjct: 1241 GSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNM 1300
Query: 2028 STMTP---MSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQ 2084
ST P + +G+ S + P QQQQQQ QQ+ Q Q QQ
Sbjct: 1301 STGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQ-QQRHDSYGNQFSTQGTPSGSPFPSQQT 1359
Query: 2085 QQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQP 2135
+QQQ + + + + H + Q+A PP P P
Sbjct: 1360 TMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAP 1410
Score = 36.2 bits (82), Expect = 0.36
Identities = 21/57 (36%), Positives = 26/57 (45%)
Query: 2107 QQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLS 2163
QQQQQQQQ+H Q + P P Q QQ QQ A L R ++ + S
Sbjct: 1327 QQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTS 1383
Score = 33.9 bits (76), Expect = 1.8
Identities = 109/488 (22%), Positives = 152/488 (31%), Gaps = 86/488 (17%)
Query: 1715 ARGEEQQRLLLYHTHLRPRPRAYYLEPLPLPPEDEEP--------PAPTL-LEPEKKAPE 1765
A G QQR +H + P +PL P+ P P P P +
Sbjct: 349 ASGGAQQRS--HHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQG 406
Query: 1766 PPKTDKPGAAPPS------TEERKKKSTKGKKRSQPA-----TKTEDYGM-GPGRSGPYG 1813
PP + G P T +R + +G+ +S + YG GP G G
Sbjct: 407 PPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQG 466
Query: 1814 VTV-------------PPDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPY-- 1858
T PP P+ +Y+Q Q+QP P PY
Sbjct: 467 QTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQ-----QPQSQP-PQLQSSQPPYSQ 520
Query: 1859 RPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKT--SVYRQQQPAVPQGQRLRQQLQ 1916
+P + P Q+ P YP TT P S S Y+QQQP P L QQ
Sbjct: 521 QPSQPPHQQSPA--PYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAA 578
Query: 1917 QSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHT-GPAGTMVPPSYSSQPYQ- 1974
Q P S QT+ + L Q + G + P SS+ Q
Sbjct: 579 YPQ------------PQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQE 626
Query: 1975 ------STHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQ---------RFSHQ 2019
+ PS+ P L L G + T G++S+Q FS
Sbjct: 627 DMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVST--SGISSSQGEQSNPAQSPFSPH 684
Query: 2020 TLQQTPMI--STMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQY 2077
T P I + +P+ + A RS + P Q + Q Q
Sbjct: 685 TSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQS 744
Query: 2078 HIRQ-----QQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQ 2132
I Q Q+ Q+ + Q +Q Q +QQ P Q
Sbjct: 745 SIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYG 804
Query: 2133 SQPQFQRQ 2140
Q + RQ
Sbjct: 805 PQGGYPRQ 812
>gi|62953127 polyhomeotic 1-like [Homo sapiens]
Length = 1004
Score = 78.2 bits (191), Expect = 8e-14
Identities = 84/291 (28%), Positives = 118/291 (40%), Gaps = 38/291 (13%)
Query: 1900 QQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSH-VGLQQHTG 1958
+ Q A QG +++ Q++ G S V ++ +SS L +Q + + + L Q G
Sbjct: 211 RNQQASAQGPQMQGSTQKAIPP-GASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGG 269
Query: 1959 PAGTMVPPSYSSQPYQSTH----------------PSTNPTLVDPTRHLQQRPSGYVHQQ 2002
+G +P S H P +V P L + V Q
Sbjct: 270 GSGNSIPGSMGPGGGGQAHGGLGQLPSSGMGGGSCPRKGTGVVQP---LPAAQTVTVSQG 326
Query: 2003 APTYGHGLTSTQRFSHQTLQQTP---MISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQ 2059
+ T + + + + QQ + T TP +Q + + T I P QQQQQ
Sbjct: 327 SQTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQI 386
Query: 2060 QQQQQQQQQQQQ---QQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQH 2116
QQ+Q QQQ QQQ+ Q +Q Q+L Q QQQQQQQQQQQ
Sbjct: 387 HLQQKQVVIQQQIAIHHQQQF---QHRQSQLLHTATHLQLAQQQQQQQQQQQ-------- 435
Query: 2117 QQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQP 2167
QQQQ Q PQP P Q+ Q+QQQ QT + LQ + P
Sbjct: 436 QQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPP 486
Score = 54.7 bits (130), Expect = 1e-06
Identities = 49/139 (35%), Positives = 57/139 (41%), Gaps = 22/139 (15%)
Query: 2011 TSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQ------------ 2058
T TQ H +QQ I Q Q ++ + QQQ Q +Q
Sbjct: 370 TYTQIQPHSLIQQQQQIHL------QQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQL 423
Query: 2059 -QQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQ 2117
QQQQQQQQQQQQQQQ Q + Q Q+ QQ Q QQQ Q Q Q
Sbjct: 424 AQQQQQQQQQQQQQQQPQATTLTAPQPPQV--PPTQQVPPSQSQQQAQTLVVQPMLQSSP 481
Query: 2118 QQQQQQAAPPQPQP-QSQP 2135
AAP P P QS+P
Sbjct: 482 LSLPPDAAPKPPIPIQSKP 500
Score = 33.5 bits (75), Expect = 2.3
Identities = 27/117 (23%), Positives = 38/117 (32%)
Query: 2050 EQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQ 2109
E + +Q + Q Q + ++Q Q L+ Q+Q Q Q QQQ
Sbjct: 2 ETESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQ 61
Query: 2110 QQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQ 2166
Q H QQA + S P Q T Q Q +S +Q
Sbjct: 62 LSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQ 118
>gi|114431248 hypothetical protein LOC205717 [Homo sapiens]
Length = 2245
Score = 75.9 bits (185), Expect = 4e-13
Identities = 49/144 (34%), Positives = 68/144 (47%), Gaps = 2/144 (1%)
Query: 2027 ISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQ 2086
++ + P S V +R T + Q +QQQ Q Q Q QQ +
Sbjct: 1398 LTRLFPPSNNFVTPALRQTEVQCGSQPSVAEQQQTQASQHLQALQQHVPAQGVSHLHSNH 1457
Query: 2087 ILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQ--FQRQGLQQ 2144
+ +QQQQQQQQQQQQQQQQQ Q +++ H Q Q + SQP Q++ LQQ
Sbjct: 1458 LYIKQQQQQQQQQQQQQQQQQAGQLRERHHLYQMQHHVPHAESSVHSQPHNVHQQRTLQQ 1517
Query: 2145 TQQQQQTAALVRQLQQQLSNTQPQ 2168
Q Q+ LV+ Q + QP+
Sbjct: 1518 EVQMQKKRNLVQGTQTSQLSLQPK 1541
Score = 66.6 bits (161), Expect = 2e-10
Identities = 65/230 (28%), Positives = 96/230 (41%), Gaps = 27/230 (11%)
Query: 1962 TMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYV----HQQAPTYGHGLTSTQRFS 2017
+ +PP+ S+ S P +NP D L + +V Q G + ++
Sbjct: 1376 SQIPPNSSN----SVVPVSNPAHGDGLTRLFPPSNNFVTPALRQTEVQCGSQPSVAEQQQ 1431
Query: 2018 HQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQ---- 2073
Q Q + P AQGV + + S + +QQQQQQQQQQQQQQQQQ Q ++
Sbjct: 1432 TQASQHLQALQQHVP--AQGV-SHLHSNHLYIKQQQQQQQQQQQQQQQQQAGQLRERHHL 1488
Query: 2074 -QQQYHIRQQQ----------QQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQ 2122
Q Q+H+ + QQ QQ+ Q Q+++ Q Q Q Q +H Q
Sbjct: 1489 YQMQHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQTSQLSLQPKHHGTDQS 1548
Query: 2123 QAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPSTN 2172
++ QP P Q Q Q+Q Q Q + + + PQ N
Sbjct: 1549 RSKTGQPHPHHQ-QMQQQMQQHFGSSQTEKSCENPSTSRNHHNHPQNHLN 1597
Score = 43.9 bits (102), Expect = 0.002
Identities = 63/349 (18%), Positives = 109/349 (31%), Gaps = 10/349 (2%)
Query: 1835 RQGSIGLYTQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYK 1894
R+ S Q+ L + R +P L ++ + P + ++ P +
Sbjct: 1324 RKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQIPPNSS 1383
Query: 1895 TSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHV-GL 1953
SV PA G L + S + + S Q T H+ L
Sbjct: 1384 NSVVPVSNPA--HGDGLTRLFPPSNNFVTPALRQTEVQCGSQPSVAEQQQTQASQHLQAL 1441
Query: 1954 QQHTGPAGTMVPPS---YSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGL 2010
QQH G S Y Q Q L++R +++Q H
Sbjct: 1442 QQHVPAQGVSHLHSNHLYIKQQQQQQQQQQQQQQQQQAGQLRERH--HLYQMQHHVPHAE 1499
Query: 2011 TSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRST--AILPEQQQQQQQQQQQQQQQQQQ 2068
+S H QQ + + + + G +++ ++ P+ Q + + Q
Sbjct: 1500 SSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQTSQLSLQPKHHGTDQSRSKTGQPHPHH 1559
Query: 2069 QQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQ 2128
QQ QQQ Q H Q ++ + Q Q QQQ +QQ +
Sbjct: 1560 QQMQQQMQQHFGSSQTEKSCENPSTSRNHHNHPQNHLNQDIMHQQQDVGSRQQGSGVSSE 1619
Query: 2129 PQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPSTNIFGRY 2177
P + + +QQ + + ++ T +P N Y
Sbjct: 1620 HVSGHNPMQRLLTSRGLEQQMVSQPSIVTRSSDMTCTPHRPERNRVSSY 1668
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens]
Length = 436
Score = 73.9 bits (180), Expect = 2e-12
Identities = 35/142 (24%), Positives = 89/142 (62%), Gaps = 9/142 (6%)
Query: 2033 MSAQGVQAGVRSTAILPEQQQQQQQQQQ--QQQQQQQQQQQQQQQQYHIRQQQQQQILRQ 2090
M Q Q G + + +++Q Q+Q++Q +Q++Q ++Q++Q +Q Q+Q++Q+ +Q
Sbjct: 194 MGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQ 253
Query: 2091 QQQQQQQQQQQQQQQQQQQQQQQ----QQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQ 2146
++Q ++Q++Q ++Q++Q ++Q++ Q+ Q +Q++Q + Q + Q + R+ +Q +
Sbjct: 254 EEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMR 313
Query: 2147 QQQQTAALVRQLQQQLSNTQPQ 2168
+Q++ +R+ ++Q+ + Q
Sbjct: 314 EQEEQ---MREQEEQMGKQEEQ 332
Score = 73.6 bits (179), Expect = 2e-12
Identities = 33/119 (27%), Positives = 75/119 (63%), Gaps = 1/119 (0%)
Query: 2050 EQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQ 2109
E Q +Q+ Q +Q++Q +Q++Q Q+ + +Q++ +R+Q++Q +Q++Q Q+Q++Q
Sbjct: 191 EGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQV 250
Query: 2110 QQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQ 2168
Q+Q++Q ++Q++Q + + + Q +Q +QT+Q++QT Q+++Q + Q
Sbjct: 251 QKQEEQMRKQEEQMREQEEQMREQEEQMLKQ-KEQTEQEEQTGEQEEQMREQEEQMREQ 308
Score = 73.2 bits (178), Expect = 3e-12
Identities = 39/145 (26%), Positives = 86/145 (59%), Gaps = 8/145 (5%)
Query: 2022 QQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQ---QQYH 2078
Q+ M M Q Q G + + +++Q +Q++Q Q+Q++Q Q+Q++Q Q+
Sbjct: 204 QEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQ 263
Query: 2079 IRQQQQQQILRQQQQQ---QQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQP 2135
+R+Q++Q +R+Q++Q Q++Q +Q++Q +Q++Q ++Q +Q ++Q+ + + Q +
Sbjct: 264 MREQEEQ--MREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE 321
Query: 2136 QFQRQGLQQTQQQQQTAALVRQLQQ 2160
Q ++ G Q+ Q +Q + Q +Q
Sbjct: 322 QEEQMGKQEEQMWEQKEQMWEQKEQ 346
Score = 73.2 bits (178), Expect = 3e-12
Identities = 27/117 (23%), Positives = 77/117 (65%)
Query: 2052 QQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQ 2111
Q+Q++Q Q+Q++Q ++Q++Q ++Q+ +R+Q++Q + +++Q +Q++Q +Q++Q ++Q++
Sbjct: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEE 303
Query: 2112 QQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQ 2168
Q ++ ++Q ++Q + Q + + + Q +Q +Q + + + ++Q+ + Q
Sbjct: 304 QMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360
Score = 72.8 bits (177), Expect = 3e-12
Identities = 32/130 (24%), Positives = 77/130 (59%)
Query: 2039 QAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQ 2098
Q G + + +++Q +Q++Q Q+Q++Q +Q++Q + Q +Q+ Q+Q++Q Q+
Sbjct: 193 QMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQK 252
Query: 2099 QQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQL 2158
Q++Q ++Q++Q ++Q++ ++Q++Q + Q + + Q Q Q +Q++Q Q+
Sbjct: 253 QEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQM 312
Query: 2159 QQQLSNTQPQ 2168
++Q + Q
Sbjct: 313 REQEEQMREQ 322
Score = 64.7 bits (156), Expect = 9e-10
Identities = 29/115 (25%), Positives = 72/115 (62%), Gaps = 5/115 (4%)
Query: 2052 QQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQ-----QQQILRQQQQQQQQQQQQQQQQQ 2106
++Q+ Q ++Q+ Q ++Q+ Q ++Q+ +R+Q+ Q+ + +Q++Q +Q++Q Q+Q+
Sbjct: 160 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQE 219
Query: 2107 QQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQ 2161
+Q +Q++Q ++Q++Q + + + Q Q+Q Q +Q++Q Q+++Q
Sbjct: 220 EQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQ 274
Score = 64.7 bits (156), Expect = 9e-10
Identities = 25/100 (25%), Positives = 65/100 (65%)
Query: 2050 EQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQ 2109
E+Q +Q++Q +Q++Q +Q++Q + + Q+Q++ +R+Q++Q ++Q++Q ++Q++Q
Sbjct: 330 EEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQM 389
Query: 2110 QQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQ 2149
++Q++Q +Q++Q + + + Q Q Q +Q++
Sbjct: 390 RKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
Score = 63.9 bits (154), Expect = 2e-09
Identities = 32/128 (25%), Positives = 76/128 (59%), Gaps = 5/128 (3%)
Query: 2022 QQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQ---QQQQQQQQQQQQQQQQYH 2078
Q+ M M Q Q G + + +++Q +Q++Q Q++Q +Q++Q Q+Q+
Sbjct: 308 QEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQ 367
Query: 2079 IRQQQQQQILRQQQQQQQQQQQQQQQQQ--QQQQQQQQQHQQQQQQQAAPPQPQPQSQPQ 2136
+R+Q++Q +++Q ++Q++Q ++Q++Q +Q++Q +Q +Q ++Q+ + + Q + Q
Sbjct: 368 VRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQ 427
Query: 2137 FQRQGLQQ 2144
+ G Q+
Sbjct: 428 EEHMGEQK 435
Score = 63.2 bits (152), Expect = 3e-09
Identities = 32/122 (26%), Positives = 69/122 (56%), Gaps = 5/122 (4%)
Query: 2050 EQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQ 2109
EQ+ Q ++Q+ Q ++Q+ Q +Q+ Q +Q +Q + Q+Q++Q +Q++Q ++Q++
Sbjct: 175 EQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEE 234
Query: 2110 QQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQP 2169
Q +Q+ Q Q+Q++ Q + Q ++Q Q +Q++Q Q+ +Q T+ +
Sbjct: 235 QMGEQEEQVQKQEEQVQKQ-----EEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEE 289
Query: 2170 ST 2171
T
Sbjct: 290 QT 291
Score = 61.6 bits (148), Expect = 8e-09
Identities = 31/109 (28%), Positives = 70/109 (64%), Gaps = 5/109 (4%)
Query: 2052 QQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQ 2111
++Q+ Q ++Q+ Q ++Q+ Q ++Q+ +R+Q+ Q +R+Q+ Q +Q+ Q +Q++Q +
Sbjct: 153 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQ--VREQEGQMGEQEGQMGEQEEQMGE 210
Query: 2112 QQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQ 2160
Q++Q Q+Q++Q + + Q + Q ++ G Q+ Q Q+Q + +Q +Q
Sbjct: 211 QEEQMQKQEEQMG---EQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQ 256
Score = 49.3 bits (116), Expect = 4e-05
Identities = 16/65 (24%), Positives = 48/65 (73%)
Query: 2050 EQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQ 2109
E+Q ++Q++Q ++Q++Q ++Q++Q + + +Q++ +R+Q++Q +Q++Q ++Q++
Sbjct: 372 EEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHM 431
Query: 2110 QQQQQ 2114
+Q++
Sbjct: 432 GEQKE 436
>gi|15812226 transcriptional regulating factor 1 [Homo sapiens]
Length = 1200
Score = 73.9 bits (180), Expect = 2e-12
Identities = 69/214 (32%), Positives = 86/214 (40%), Gaps = 43/214 (20%)
Query: 1954 QQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTST 2013
Q+ P +P Y P Q HP L P + Q P T GH
Sbjct: 187 QKPMEPPAPAIPSRYQQVP-QQPHPGFTGGLSKPALQVGQHP---------TQGHLYYDY 236
Query: 2014 QRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQ 2073
Q Q L Q P+ QG Q +++ +L + QQ QQ Q QQQQQ QQ+
Sbjct: 237 Q----QPLAQVPV---------QGGQP-LQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQR 282
Query: 2074 QQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQ------------QQQQQHQQQQQ 2121
I+ Q QQ +R Q Q QQQQ QQ Q QQ+ Q QH Q+QQ
Sbjct: 283 ISMQEIQTQPQQ--IRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQ 340
Query: 2122 QQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALV 2155
QQ QP P + R Q T +Q T L+
Sbjct: 341 QQQMHLQP-----PSYHRDPHQYTPEQAHTVQLI 369
Score = 65.1 bits (157), Expect = 7e-10
Identities = 87/301 (28%), Positives = 112/301 (37%), Gaps = 63/301 (20%)
Query: 1881 TMTGVMGLEPSSYKTSVYRQQQ-----PAVPQGQRLRQQLQQSQ-GMLGQSSVHQMTPSS 1934
T + VM P S + Q+ PA+P R +Q QQ G G S P+
Sbjct: 168 TQSAVMDGAPDSALRQLLSQKPMEPPAPAIPS--RYQQVPQQPHPGFTGGLS----KPAL 221
Query: 1935 SYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQR 1994
G +QG+ Y L Q P Q P P ++ ++H+QQ
Sbjct: 222 QVGQHPTQGHLYYDYQQPLAQ---------------VPVQGGQPLQAPQML--SQHMQQM 264
Query: 1995 PSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQ 2054
HQ P QR S Q +Q P + P Q P QQQQ
Sbjct: 265 QQ---HQYYPPQQQQQAGQQRISMQEIQTQPQ--QIRPSQPQP-----------PPQQQQ 308
Query: 2055 QQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQ 2114
QQ Q QQ+Q Q Q Q Q Q L++QQQQQ Q + Q +Q
Sbjct: 309 PQQLQLQQRQGSMQIPQYYQ------PQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQ 362
Query: 2115 QHQQQ-------QQQQAAPPQPQPQSQPQFQRQGLQQTQQ----QQQTAALVRQLQQQLS 2163
H Q Q PQ QP S P +Q+ L Q QQ Q +T + RQ Q LS
Sbjct: 363 AHTVQLIPLGSMSQYYYQEPQ-QPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLS 421
Query: 2164 N 2164
+
Sbjct: 422 S 422
Score = 39.3 bits (90), Expect = 0.043
Identities = 87/447 (19%), Positives = 145/447 (32%), Gaps = 57/447 (12%)
Query: 1750 EPPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGK---KRSQPATKTEDYGMGP 1806
EPPAP + ++ P+ P G + + T+G QP + G P
Sbjct: 191 EPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQP 250
Query: 1807 GRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRPVRLPMQ 1866
+ P L H + + Q Y Q AG R+ P Q
Sbjct: 251 -------LQAPQMLSQH-----MQQMQQHQ----YYPPQQQQQAGQQRISMQEIQTQPQQ 294
Query: 1867 KLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSS 1926
P++P P + S + Y Q QP + Q +QQ Q
Sbjct: 295 IRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRD 354
Query: 1927 VHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVD 1986
HQ TP ++ +Q +S Q+ P YS YQ +H S + D
Sbjct: 355 PHQYTPEQAHTVQLIP--LGSMSQYYYQEPQQP--------YSHPLYQQSHLSQHQQRED 404
Query: 1987 PT-------RHLQQRPSGYVHQQAPTYGHGLTSTQRFSH--QTLQQTPMIST----MTPM 2033
R Q S + P G G ++ + TL P++S + M
Sbjct: 405 SQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNM 464
Query: 2034 SAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQ 2093
Q Q + +A+ P+ + Q + Q + +Q+ + + I ++ +
Sbjct: 465 GPQHQQ--LSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFK 522
Query: 2094 Q------QQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQ 2147
+ + +Q++ ++ Q Q PP P P PQ + T
Sbjct: 523 NLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPM 582
Query: 2148 QQQTAALVRQLQQQLSNTQPQPSTNIF 2174
+ V+ L P+PS+ F
Sbjct: 583 VMPVSVPVKLL-------PPKPSSQGF 602
Score = 33.5 bits (75), Expect = 2.3
Identities = 40/189 (21%), Positives = 74/189 (39%), Gaps = 23/189 (12%)
Query: 1860 PVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTS--------VYRQQQPAVPQGQRL 1911
PV +P++ LP +P+ G +T+ + + S + R+ QP+VP+ +
Sbjct: 585 PVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAEEP 644
Query: 1912 RQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGY---TPYVSHVGLQQHTGPAGTMVPPSY 1968
+ +Q+ + + + P SY + Y T Y S + + G ++ P++
Sbjct: 645 LKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLRSPRVLGD-HLLLDPTH 703
Query: 1969 SSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMIS 2028
PY T P ++ P R + SG + GHG + + L TP +
Sbjct: 704 ELPPY------TPPPMLSPVR----QGSG-LFSNVLISGHGPGAHPQLPLTPLTPTPRVL 752
Query: 2029 TMTPMSAQG 2037
S G
Sbjct: 753 LCRSNSIDG 761
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,644,205
Number of Sequences: 37866
Number of extensions: 4942204
Number of successful extensions: 106319
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 804
Number of HSP's successfully gapped in prelim test: 597
Number of HSP's that attempted gapping in prelim test: 36565
Number of HSP's gapped (non-prelim): 23424
length of query: 2177
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2059
effective length of database: 13,779,330
effective search space: 28371640470
effective search space used: 28371640470
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.