BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|110347414 fibroblast growth factor receptor substrate 2 [Homo sapiens] (508 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|110347414 fibroblast growth factor receptor substrate 2 [Homo... 1040 0.0 gi|110347408 fibroblast growth factor receptor substrate 2 [Homo... 1040 0.0 gi|5730059 fibroblast growth factor receptor substrate 3 [Homo s... 441 e-123 gi|4503357 docking protein 1 [Homo sapiens] 60 6e-09 gi|47575849 docking protein 6 [Homo sapiens] 55 2e-07 gi|41406050 docking protein 2 [Homo sapiens] 54 4e-07 gi|221554537 docking protein 3 isoform 1 [Homo sapiens] 52 2e-06 gi|29544726 docking protein 5 [Homo sapiens] 50 5e-06 gi|20070302 docking protein 4 [Homo sapiens] 50 6e-06 gi|110349719 titin isoform N2-A [Homo sapiens] 36 0.095 gi|110349717 titin isoform novex-2 [Homo sapiens] 36 0.095 gi|110349713 titin isoform novex-1 [Homo sapiens] 36 0.095 gi|110349715 titin isoform N2-B [Homo sapiens] 36 0.095 gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 35 0.21 gi|111185957 downstream of tyrosine kinase 7 [Homo sapiens] 34 0.28 gi|7662230 ring finger protein 40 [Homo sapiens] 34 0.28 gi|208022661 hypothetical protein LOC57701 [Homo sapiens] 34 0.36 gi|44771211 mediator complex subunit 13-like [Homo sapiens] 33 0.61 gi|122692281 hypothetical protein LOC645369 [Homo sapiens] 33 0.61 gi|61102725 la related protein isoform 2 [Homo sapiens] 33 0.61 gi|39725634 la related protein isoform 1 [Homo sapiens] 33 0.61 gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member... 32 1.0 gi|208431824 forkhead box I3 [Homo sapiens] 32 1.0 gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens] 32 1.0 gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 32 1.4 gi|30061567 La ribonucleoprotein domain family member 2 isoform ... 32 1.4 gi|10863935 reticulon 1 isoform A [Homo sapiens] 32 1.4 gi|5031805 insulin receptor substrate 1 [Homo sapiens] 32 1.8 gi|148612879 polyhomeotic like 3 [Homo sapiens] 32 1.8 gi|239755199 PREDICTED: hypothetical protein [Homo sapiens] 31 2.3 >gi|110347414 fibroblast growth factor receptor substrate 2 [Homo sapiens] Length = 508 Score = 1040 bits (2688), Expect = 0.0 Identities = 508/508 (100%), Positives = 508/508 (100%) Query: 1 MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNELGSGIMELTDTELILYTRKRDSVKWHYL 60 MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNELGSGIMELTDTELILYTRKRDSVKWHYL Sbjct: 1 MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNELGSGIMELTDTELILYTRKRDSVKWHYL 60 Query: 61 CLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVER 120 CLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVER Sbjct: 61 CLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVER 120 Query: 121 NNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGE 180 NNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGE Sbjct: 121 NNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGE 180 Query: 181 ESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTPKEEPSSIEDRDP 240 ESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTPKEEPSSIEDRDP Sbjct: 181 ESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTPKEEPSSIEDRDP 240 Query: 241 QILLEPEGVKFVLGPTPVQKQLMEKEKLEQLGRDQVSGSGANNTEWDTGYDSDERRDAPS 300 QILLEPEGVKFVLGPTPVQKQLMEKEKLEQLGRDQVSGSGANNTEWDTGYDSDERRDAPS Sbjct: 241 QILLEPEGVKFVLGPTPVQKQLMEKEKLEQLGRDQVSGSGANNTEWDTGYDSDERRDAPS 300 Query: 301 VNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRTALLNYENLPSLPPVWE 360 VNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRTALLNYENLPSLPPVWE Sbjct: 301 VNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRTALLNYENLPSLPPVWE 360 Query: 361 ARKLSRDEDDNLGPKTPSLNGYHNNLDPMHNYVNTENVTVPASAHKIEYSRRRDCTPTVF 420 ARKLSRDEDDNLGPKTPSLNGYHNNLDPMHNYVNTENVTVPASAHKIEYSRRRDCTPTVF Sbjct: 361 ARKLSRDEDDNLGPKTPSLNGYHNNLDPMHNYVNTENVTVPASAHKIEYSRRRDCTPTVF 420 Query: 421 NFDIRRPSLEHRQLNYIQVDLEGGSDSDNPQTPKTPTTPLPQTPTRRTELYAVIDIERTA 480 NFDIRRPSLEHRQLNYIQVDLEGGSDSDNPQTPKTPTTPLPQTPTRRTELYAVIDIERTA Sbjct: 421 NFDIRRPSLEHRQLNYIQVDLEGGSDSDNPQTPKTPTTPLPQTPTRRTELYAVIDIERTA 480 Query: 481 AMSNLQKALPRDDGTSRKTRHNSTDLPM 508 AMSNLQKALPRDDGTSRKTRHNSTDLPM Sbjct: 481 AMSNLQKALPRDDGTSRKTRHNSTDLPM 508 >gi|110347408 fibroblast growth factor receptor substrate 2 [Homo sapiens] Length = 508 Score = 1040 bits (2688), Expect = 0.0 Identities = 508/508 (100%), Positives = 508/508 (100%) Query: 1 MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNELGSGIMELTDTELILYTRKRDSVKWHYL 60 MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNELGSGIMELTDTELILYTRKRDSVKWHYL Sbjct: 1 MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNELGSGIMELTDTELILYTRKRDSVKWHYL 60 Query: 61 CLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVER 120 CLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVER Sbjct: 61 CLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVER 120 Query: 121 NNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGE 180 NNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGE Sbjct: 121 NNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGE 180 Query: 181 ESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTPKEEPSSIEDRDP 240 ESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTPKEEPSSIEDRDP Sbjct: 181 ESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTPKEEPSSIEDRDP 240 Query: 241 QILLEPEGVKFVLGPTPVQKQLMEKEKLEQLGRDQVSGSGANNTEWDTGYDSDERRDAPS 300 QILLEPEGVKFVLGPTPVQKQLMEKEKLEQLGRDQVSGSGANNTEWDTGYDSDERRDAPS Sbjct: 241 QILLEPEGVKFVLGPTPVQKQLMEKEKLEQLGRDQVSGSGANNTEWDTGYDSDERRDAPS 300 Query: 301 VNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRTALLNYENLPSLPPVWE 360 VNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRTALLNYENLPSLPPVWE Sbjct: 301 VNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRTALLNYENLPSLPPVWE 360 Query: 361 ARKLSRDEDDNLGPKTPSLNGYHNNLDPMHNYVNTENVTVPASAHKIEYSRRRDCTPTVF 420 ARKLSRDEDDNLGPKTPSLNGYHNNLDPMHNYVNTENVTVPASAHKIEYSRRRDCTPTVF Sbjct: 361 ARKLSRDEDDNLGPKTPSLNGYHNNLDPMHNYVNTENVTVPASAHKIEYSRRRDCTPTVF 420 Query: 421 NFDIRRPSLEHRQLNYIQVDLEGGSDSDNPQTPKTPTTPLPQTPTRRTELYAVIDIERTA 480 NFDIRRPSLEHRQLNYIQVDLEGGSDSDNPQTPKTPTTPLPQTPTRRTELYAVIDIERTA Sbjct: 421 NFDIRRPSLEHRQLNYIQVDLEGGSDSDNPQTPKTPTTPLPQTPTRRTELYAVIDIERTA 480 Query: 481 AMSNLQKALPRDDGTSRKTRHNSTDLPM 508 AMSNLQKALPRDDGTSRKTRHNSTDLPM Sbjct: 481 AMSNLQKALPRDDGTSRKTRHNSTDLPM 508 >gi|5730059 fibroblast growth factor receptor substrate 3 [Homo sapiens] Length = 492 Score = 441 bits (1133), Expect = e-123 Identities = 249/522 (47%), Positives = 327/522 (62%), Gaps = 44/522 (8%) Query: 1 MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNELGSGIMELTDTELILYTRKRDSVKWHYL 60 MGSCCSC ++D+VPDNH KFKV NVDD+G ELGSG+MELT +EL+L+ +R++V+W YL Sbjct: 1 MGSCCSCLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHRREAVRWPYL 60 Query: 61 CLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPV-VE 119 CLRRYGYDSNLFSFESGRRCQTGQGIFAFKC+RAEE+FN+LQ++MQ NSINV+EEPV + Sbjct: 61 CLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPVIIT 120 Query: 120 RNNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVG 179 RN+H EL++PR P+ P G+ + NG P G+ + R S S R PS+G Sbjct: 121 RNSHPAELDLPRAPQPPNALGYTVSSFSNGCP-----GEGPRFSAPRRLSTSSLRHPSLG 175 Query: 180 EESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTP-KEEPSSIEDR 238 EESTH L+ +EQ HTYVNT +++ + PL E P + + R Sbjct: 176 EESTHALIAPDEQSHTYVNTPASEDDHRRGRHCLQPL------PEGQAPFLPQARGPDQR 229 Query: 239 DPQILLEPEGVKFVLGPTPVQKQLMEKEKLEQLGRDQVSGSGANNTEWDTGYDSDERRDA 298 DPQ+ L+P VKFVLGPTP ++ +++ + L D + NN E + + Sbjct: 230 DPQVFLQPGQVKFVLGPTPARRHMVKCQGLCPSLHDPPHHN--NNNEAPS--------EC 279 Query: 299 PSVNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRTALLNYENLPSLPPV 358 P+ K YEN+ G G+ RG S + N A RR ALL+YENLP LPPV Sbjct: 280 PAQPKCTYENVTG-------GLWRGAGWRLSPEE-PGWNGLAHRRAALLHYENLPPLPPV 331 Query: 359 WEARKL-----SRDEDDNLGPKTPSLNGYHNNLD---PMHNYVNTENVTVPASAHKIEYS 410 WE++ + D+ D+ TPS NG+ + + P+ +T + + + Sbjct: 332 WESQAQQLGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTSTRAAIRSHGSFPVPLT 391 Query: 411 RRRDCTPTVFNFDIRRPSLE-HRQLNYIQVDLE--GGSDSDNPQTPKTPTTPLPQT-PTR 466 RRR +P VFNFD RRP E RQLNYIQV+L+ GG PQ P +P P+P T P R Sbjct: 392 RRRG-SPRVFNFDFRRPGPEPPRQLNYIQVELKGWGGDRPKGPQNPSSPQAPMPTTHPAR 450 Query: 467 RTELYAVIDIERTAAMSNLQKALPRDDGTSRKTRHNSTDLPM 508 ++ YAVID+++T AMSNLQ+ALPRDDGT+RKTRHNSTDLP+ Sbjct: 451 SSDSYAVIDLKKTVAMSNLQRALPRDDGTARKTRHNSTDLPL 492 >gi|4503357 docking protein 1 [Homo sapiens] Length = 481 Score = 59.7 bits (143), Expect = 6e-09 Identities = 60/235 (25%), Positives = 95/235 (40%), Gaps = 41/235 (17%) Query: 34 GSGIMELTDTELILYTRKRDS------VKWHYLCLRRYGYDSNLFSFESGRRCQTGQGIF 87 GS ++ + L L T S + W Y LRRYG D +FSFE+GRRC +G G F Sbjct: 172 GSYVLRVEAERLTLLTVGAQSQILEPLLSWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTF 231 Query: 88 AFKCARAEELFNMLQEIMQNNSINVVE---EPVVERNNHQTELEVPRTPRTPTTPGFAAQ 144 F+ A+ ++F ++ + V+ ++H+ E+ + P +P P Sbjct: 232 TFQTAQGNDIFQAVETAIHRQKAQGKAGQGHDVLRADSHEGEVAEGKLP-SPPGPQELLD 290 Query: 145 NLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTTGVQE 204 + P Y + S+ A PS + PL Q GVQ Sbjct: 291 SPPALY-------------AEPLDSLRIAPCPSQDSLYSDPLDSTSAQA-----GEGVQR 332 Query: 205 ERKNRTSVHVPLEARVSNAESSTPKEEPSSIEDRDPQILLEPEGVKFVLGPTPVQ 259 ++ ++ + ++ A+ + PKE+P I EPEG L P P Q Sbjct: 333 KKPLYWDLYEHAQQQLLKAKLTDPKEDP---------IYDEPEG----LAPVPPQ 374 >gi|47575849 docking protein 6 [Homo sapiens] Length = 331 Score = 54.7 bits (130), Expect = 2e-07 Identities = 48/169 (28%), Positives = 69/169 (40%), Gaps = 22/169 (13%) Query: 34 GSGIMELTDTELILYTRKRDSVK---WHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFK 90 G M++T + L+ VK W LRRYG DS F+FESGR C TG+G+F F+ Sbjct: 153 GECTMQITHENIYLWDIHNAKVKLVMWPLSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQ 212 Query: 91 CARAEELFNMLQEIMQNNSINVVEE------PVVERNNHQTELEVPRT-------PRTPT 137 E M+ + + + ++ + E+ + ++ QT L P T PR+ Sbjct: 213 TREGE----MIYQKVHSATLAIAEQHERLMLEMEQKARLQTSLTEPMTLSKSISLPRSAY 268 Query: 138 TPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPL 186 QN G SS S A P EE+ PL Sbjct: 269 WHHITRQNSVGEIYSLQGHGFGSSKMSRAQTFPSYA--PEQSEEAQQPL 315 >gi|41406050 docking protein 2 [Homo sapiens] Length = 412 Score = 53.5 bits (127), Expect = 4e-07 Identities = 26/62 (41%), Positives = 37/62 (59%), Gaps = 2/62 (3%) Query: 57 WHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIM--QNNSINVVE 114 W Y LRR+G D FSFE+GRRC +G+G F F+ + E+F L+E + Q N+ Sbjct: 194 WPYRFLRRFGRDKVTFSFEAGRRCVSGEGNFEFETRQGNEIFLALEEAISAQKNAAPATP 253 Query: 115 EP 116 +P Sbjct: 254 QP 255 >gi|221554537 docking protein 3 isoform 1 [Homo sapiens] Length = 496 Score = 51.6 bits (122), Expect = 2e-06 Identities = 55/232 (23%), Positives = 82/232 (35%), Gaps = 32/232 (13%) Query: 57 WHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEP 116 W Y LR++G D +FSFE+GRRC +G+G+FAF A +L V Sbjct: 259 WPYHFLRKFGSDKGVFSFEAGRRCHSGEGLFAFSTPCAPDL------------CRAVAGA 306 Query: 117 VVERNNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLP 176 + + EL P+ P + + P P P P+ L Sbjct: 307 IARQRERLPELTRPQPCPLPRATSLPSLDTPGELREMP--------PGPEPPTSRKMHLA 358 Query: 177 SVGEESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESS--------TP 228 G +S PLL+ E +R + + L + E+S P Sbjct: 359 EPGPQSL-PLLLGPEPNDLASGLYASVCKRASGPPGNEHLYENLCVLEASPTLHGGEPEP 417 Query: 229 KEEPSSIEDRDPQILLEPEGVKFVLGPTPVQKQLMEKEKLEQLGRDQVSGSG 280 E P S I + + + P P +E + L DQV G+G Sbjct: 418 HEGPGSRSPTTSPIYHNGQDLSW---PGPANDSTLEAQYRRLLELDQVEGTG 466 >gi|29544726 docking protein 5 [Homo sapiens] Length = 306 Score = 50.1 bits (118), Expect = 5e-06 Identities = 24/68 (35%), Positives = 39/68 (57%), Gaps = 3/68 (4%) Query: 34 GSGIMELTDTELILYTRKRDSVK---WHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFK 90 G +++T + L+ + VK W LRRYG D+ F+FE+GR C+TG+G+F F+ Sbjct: 153 GECALQITYEYICLWDVQNPRVKLISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQ 212 Query: 91 CARAEELF 98 E ++ Sbjct: 213 TRDGEAIY 220 >gi|20070302 docking protein 4 [Homo sapiens] Length = 326 Score = 49.7 bits (117), Expect = 6e-06 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 6/87 (6%) Query: 55 VKWHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIM-----QNNS 109 V W LRRYG D+ F+FE+GR C G+G++ F+ E+++ + Q+ Sbjct: 177 VSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKR 236 Query: 110 INVVEEPVVERNNHQTE-LEVPRTPRT 135 + + E V N TE P TP T Sbjct: 237 VLLEMEKNVRLLNKGTEHYSYPCTPTT 263 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 35.8 bits (81), Expect = 0.095 Identities = 21/53 (39%), Positives = 32/53 (60%), Gaps = 6/53 (11%) Query: 447 SDNPQTPKTPTTPLPQTPTRRTELYAVIDIERTAAMSNLQKALPRDDGTSRKT 499 S+ P TPKTP P P+ P+ E V+D+ +++ +L + P+DDG SR T Sbjct: 30316 SEEPVTPKTPLNP-PEPPSNPPE---VLDVTKSSV--SLSWSRPKDDGGSRVT 30362 >gi|110349717 titin isoform novex-2 [Homo sapiens] Length = 27118 Score = 35.8 bits (81), Expect = 0.095 Identities = 21/53 (39%), Positives = 32/53 (60%), Gaps = 6/53 (11%) Query: 447 SDNPQTPKTPTTPLPQTPTRRTELYAVIDIERTAAMSNLQKALPRDDGTSRKT 499 S+ P TPKTP P P+ P+ E V+D+ +++ +L + P+DDG SR T Sbjct: 24011 SEEPVTPKTPLNP-PEPPSNPPE---VLDVTKSSV--SLSWSRPKDDGGSRVT 24057 >gi|110349713 titin isoform novex-1 [Homo sapiens] Length = 27051 Score = 35.8 bits (81), Expect = 0.095 Identities = 21/53 (39%), Positives = 32/53 (60%), Gaps = 6/53 (11%) Query: 447 SDNPQTPKTPTTPLPQTPTRRTELYAVIDIERTAAMSNLQKALPRDDGTSRKT 499 S+ P TPKTP P P+ P+ E V+D+ +++ +L + P+DDG SR T Sbjct: 23944 SEEPVTPKTPLNP-PEPPSNPPE---VLDVTKSSV--SLSWSRPKDDGGSRVT 23990 >gi|110349715 titin isoform N2-B [Homo sapiens] Length = 26926 Score = 35.8 bits (81), Expect = 0.095 Identities = 21/53 (39%), Positives = 32/53 (60%), Gaps = 6/53 (11%) Query: 447 SDNPQTPKTPTTPLPQTPTRRTELYAVIDIERTAAMSNLQKALPRDDGTSRKT 499 S+ P TPKTP P P+ P+ E V+D+ +++ +L + P+DDG SR T Sbjct: 23819 SEEPVTPKTPLNP-PEPPSNPPE---VLDVTKSSV--SLSWSRPKDDGGSRVT 23865 >gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical region 1 [Homo sapiens] Length = 1400 Score = 34.7 bits (78), Expect = 0.21 Identities = 87/386 (22%), Positives = 126/386 (32%), Gaps = 54/386 (13%) Query: 119 ERNNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSV 178 E H T +P P + P + S S+ R P PS Sbjct: 441 EPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSP 500 Query: 179 GEESTHPLLVAEEQVHTYVNTTGVQEER------KNRTSVHVPLEARVSNA-ESSTPKE- 230 E + + A E +T + G E R K S P E R + A E +TP Sbjct: 501 AEPTENRERTANE--NTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPA 558 Query: 231 EPSSIEDRDP-------QILLEP--EGVKFVLG-----PTPVQKQLMEKEKLEQLGRDQV 276 EP+ R P EP G + L P+P + E E+ ++ Sbjct: 559 EPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPT----ENRERTANEKT 614 Query: 277 SGSGANNTEWDTGYDSDERRDAPSVNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNI 336 + S A TE + PS L NG P A+ + TS+S T++ Sbjct: 615 TPSPAEPTENGDRTPLANEKTTPS---LAEPTENGQRTPFANE----KTTSSSAEPTEH- 666 Query: 337 NNSAQRRTALLNYENLPSLPPVWEARKLSRDEDDNLGPKTPSLNGYHNN--------LDP 388 + RT L N PS E R+ + +E+ P P+ N +P Sbjct: 667 ----EERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEP 722 Query: 389 MHNYVNTENV-TVPASAHKIEYSRRRDCTPTVFNFDIRRPSLEHRQLNYIQVD----LEG 443 N T N T + A E +R P+ EH + + + Sbjct: 723 TENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPT-EHGERTPLANENTTLSPA 781 Query: 444 GSDSDNPQTPKTPTTPLPQTPTRRTE 469 G + +T TTP P PT E Sbjct: 782 GPTENRERTANEKTTPFPAEPTENRE 807 Score = 30.0 bits (66), Expect = 5.2 Identities = 71/352 (20%), Positives = 121/352 (34%), Gaps = 55/352 (15%) Query: 177 SVGEESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTPKEEPSSIE 236 S+ E + H A E NT E +NR R +N ++ EP+ Sbjct: 343 SLAEPTEHGGRTANEN-----NTPSPAEPTENRE--------RTANENTTLSPAEPTENR 389 Query: 237 DRDPQILLEPEGVKFVLGPTPVQKQLMEK----------EKLEQLGRDQVSGSGANNTEW 286 +R P F GPT ++ + E E+ + + S A TE Sbjct: 390 ERTANENTAP----FPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEH 445 Query: 287 DTGYDSDERRDAPSVNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRTAL 346 ++ +P+ +G P A+ + TS+S T++ RT L Sbjct: 446 GERTANENTTPSPAE-----PTEHGERTPFAND----KTTSSSAESTEH-----GERTPL 491 Query: 347 LNYENLPSLPPVWEARKLSRDEDDNLGPKTPSLN-----GYHNNLDPMHNYVNTENV--- 398 N PS E R+ + +E+ P P+ N L P+ N E Sbjct: 492 ANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANE 551 Query: 399 -TVPASAHKIEYSRRRDCTPTVFNFDIRRPSLEHRQLNYIQVDLEGGSDSD----NPQTP 453 T P+ A E +R P+ EH + + + S ++ +T Sbjct: 552 KTTPSPAEPTENGQRTPFANEKTTSSSAEPT-EHGERTPLANENTTPSPAEPTENRERTA 610 Query: 454 KTPTTPLPQTPTRRTELYAVIDIERTAAMSNLQKALPRDDGTSRKTRHNSTD 505 TTP P PT + + + + T +++ + R + KT +S + Sbjct: 611 NEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAE 662 >gi|111185957 downstream of tyrosine kinase 7 [Homo sapiens] Length = 504 Score = 34.3 bits (77), Expect = 0.28 Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 2/68 (2%) Query: 32 ELGSGIMELTDTELILYTRKRDSV--KWHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAF 89 E G + L + L+L +V +W LRRYG + F FE G RC G+F Sbjct: 125 ESGPATLHLCNDVLVLARDIPPAVTGQWKLSDLRRYGAVPSGFIFEGGTRCGYWAGVFFL 184 Query: 90 KCARAEEL 97 A E++ Sbjct: 185 SSAEGEQI 192 >gi|7662230 ring finger protein 40 [Homo sapiens] Length = 1001 Score = 34.3 bits (77), Expect = 0.28 Identities = 54/212 (25%), Positives = 80/212 (37%), Gaps = 44/212 (20%) Query: 92 ARAEELFNMLQ-EIMQNNSINVVEEPV----------VERNNHQTELEVPRTPRTPTTPG 140 A+ + + ML+ E QN + N P+ ++ +NHQ + + R R Sbjct: 453 AQVRKEYEMLRIEFEQNLAANEQAGPINREMRHLISSLQNHNHQLKGDAQRYKRK----- 507 Query: 141 FAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPLLVAEEQVH------ 194 G R + G A S P+ HP P+ G+E P V+ Sbjct: 508 LREVQAEIGKLRAQASGSAHSTPNLGHPEDSGVSAPAPGKEEGGPGPVSTPDNRKEMAPV 567 Query: 195 --TYVNTTGVQEERKNRTSVHVPLEARVSNAESSTPKEEPSSIEDRDPQI-----LLEPE 247 T TT V++E VP E + + TP + S R+P+ L E E Sbjct: 568 PGTTTTTTSVKKEEL------VPSE---EDFQGITPGAQGPSSRGREPEARPKRELRERE 618 Query: 248 GVKFVLGPTPVQKQL----MEKEKLEQLGRDQ 275 G LGP PV L EK K+E+ R + Sbjct: 619 GPS--LGPPPVASALSRADREKAKVEETKRKE 648 >gi|208022661 hypothetical protein LOC57701 [Homo sapiens] Length = 1334 Score = 33.9 bits (76), Expect = 0.36 Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 17/107 (15%) Query: 95 EELFNMLQEIMQNNSINVVEEPVVERNNHQTELEVPRTPRTPTTPGF-----AAQNLPNG 149 E + ++ + + S P+ Q LEVP+ P +PG ++ P G Sbjct: 557 ENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVPPSPCLPESYPYG 616 Query: 150 YPRYPSF---GDASSHP-------SSRHPSVGSARLPSVGEESTHPL 186 P+ S G S HP SS+ PS GS R P G+ + PL Sbjct: 617 SPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRP--GDPGSTPL 661 >gi|44771211 mediator complex subunit 13-like [Homo sapiens] Length = 2210 Score = 33.1 bits (74), Expect = 0.61 Identities = 31/105 (29%), Positives = 42/105 (40%), Gaps = 12/105 (11%) Query: 107 NNSINVVEEPVVERNNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSF--GDASSHPS 164 N+ V+ P R + T PRTPRTP TP G +Y S G +S PS Sbjct: 1032 NSGAGVLPSPATPRFSVPT----PRTPRTPRTPRGGGTASGQGSVKYDSTDQGSPASTPS 1087 Query: 165 SRHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTTGVQEERKNR 209 + P L SV + P+ A T + + V K+R Sbjct: 1088 TTRP------LNSVEPATMQPIPEAHSLYVTLILSDSVMNIFKDR 1126 >gi|122692281 hypothetical protein LOC645369 [Homo sapiens] Length = 621 Score = 33.1 bits (74), Expect = 0.61 Identities = 39/159 (24%), Positives = 56/159 (35%), Gaps = 30/159 (18%) Query: 126 ELEVPRTPRTPTTPGFA---AQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEES 182 + P +P P +PG A + L P S P+ R + PS + Sbjct: 477 DYRAPPSPEPPPSPGSADPDSSPLAKAASPSPPLRLEGSPPTRRDSGSSQSDDPSSSNKG 536 Query: 183 THPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTPK---EEPSSIEDRD 239 PL A + ++ Q R S + A V AE S+P+ +EP + E Sbjct: 537 YTPLREAGTSTESVLDAVAGQ----TRDSA---VAAPVLGAEQSSPEGASQEPPTAEQ-- 587 Query: 240 PQILLEPEGVKFVLGPTPVQKQLMEKEKLEQLGRDQVSG 278 P PVQ+Q KEKL + R G Sbjct: 588 ---------------PQPVQRQFTNKEKLIMISRSHAIG 611 >gi|61102725 la related protein isoform 2 [Homo sapiens] Length = 1096 Score = 33.1 bits (74), Expect = 0.61 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 9/55 (16%) Query: 449 NPQTPKTPTTPLPQTPTRRTELYAVIDIERTAAMSNLQKALPRDDGTSRKTRHNS 503 N +TP+TP TP + ++ + Y V+ RT L +PR RKTRH+S Sbjct: 779 NTRTPRTPRTPQLKDSSQTSRFYPVVKEGRT-----LDAKMPR----KRKTRHSS 824 >gi|39725634 la related protein isoform 1 [Homo sapiens] Length = 1019 Score = 33.1 bits (74), Expect = 0.61 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 9/55 (16%) Query: 449 NPQTPKTPTTPLPQTPTRRTELYAVIDIERTAAMSNLQKALPRDDGTSRKTRHNS 503 N +TP+TP TP + ++ + Y V+ RT L +PR RKTRH+S Sbjct: 702 NTRTPRTPRTPQLKDSSQTSRFYPVVKEGRT-----LDAKMPR----KRKTRHSS 747 >gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 [Homo sapiens] Length = 1168 Score = 32.3 bits (72), Expect = 1.0 Identities = 36/152 (23%), Positives = 61/152 (40%), Gaps = 9/152 (5%) Query: 125 TELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLP---SVGEE 181 +E +P P P +P A + N +P P+ P V +L SV E Sbjct: 573 SESHLPEEP-APLSPQQAFRRRANTLSHFPIECQEPPQPARGSPGVSQRKLMRYHSVSTE 631 Query: 182 STHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSN----AESSTPKEEPSSIED 237 + H E + + ++ +G + R S + RV+ +SS+ E+ S + + Sbjct: 632 TPHERKDFESKAN-HLGDSGGTPVKTRRHSWRQQIFLRVATPQKACDSSSRYEDYSELGE 690 Query: 238 RDPQILLEPEGVKFVLGPTPVQKQLMEKEKLE 269 P+ LEP GP P +K+ +E E Sbjct: 691 LPPRSPLEPVCEDGPFGPPPEEKKRTSRELRE 722 >gi|208431824 forkhead box I3 [Homo sapiens] Length = 420 Score = 32.3 bits (72), Expect = 1.0 Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 2/64 (3%) Query: 163 PSSRHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSN 222 P SRH + A+LPS G S P ++E T + R+S + P A S Sbjct: 335 PGSRHLGIQGAQLPSSGVFS--PTSISEASADTLQLSNSTSNSTGQRSSYYSPFPASTSG 392 Query: 223 AESS 226 +SS Sbjct: 393 GQSS 396 >gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens] Length = 400 Score = 32.3 bits (72), Expect = 1.0 Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 8/150 (5%) Query: 253 LGPTPVQKQLMEKEKLEQLGRDQVSGSGANNTEWDTGYDSDERRDAPSVNKLVYENIN-G 311 + P P + +K+ L L R + SG+ D SD A K++ ++ G Sbjct: 160 VAPLPTIYKRQKKQDLTLLPRLECSGTNTTYCSLDLPSSSDPPILASQNTKIIDSELSDG 219 Query: 312 LSIPSASGVRRGRLTSTSTSDTQNINNSAQRRTALLNYENLPSLPPVWEARK------LS 365 +++ A R + + Q I ++++R+ LLN + SL V E RK L+ Sbjct: 220 IAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLN-QRFESLCAVLEERKGELLQALA 278 Query: 366 RDEDDNLGPKTPSLNGYHNNLDPMHNYVNT 395 R++++ L + Y ++L+ V + Sbjct: 279 REQEEKLQRVRGLIRQYGDHLEASSKLVES 308 >gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo sapiens] Length = 1393 Score = 32.0 bits (71), Expect = 1.4 Identities = 73/374 (19%), Positives = 126/374 (33%), Gaps = 43/374 (11%) Query: 158 DASSHPSSRHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTT---GVQEERKNRTSVHV 214 + S +V S +L + ++ + A E + T G N S Sbjct: 244 EESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAE 303 Query: 215 PLEARVSNAESSTPKEEPSSIEDRDPQILLEPEGVKFVLGPTPVQKQLMEK--------- 265 P E R A +T IE+R+ F GPT ++ + Sbjct: 304 PTENRERTANENTTLSPAEPIENRERTA--NENTAPFPAGPTENREMTANENTTLFPAEP 361 Query: 266 -EKLEQLGRDQVSGSGANNTEWDTGYDSDERRDAPSVNKLVYENINGLSIPSASGVRRGR 324 E E+ + + S A TE ++ +P+ +G P A+ + Sbjct: 362 TEHGERTANENTTPSPAEPTEHGERTANENTTPSPAE-----PTEHGERTPFAND----K 412 Query: 325 LTSTSTSDTQNINNSAQRRTALLNYENLPSLPPVWEARKLSRDEDDNLGPKTPSLN---- 380 TS+S T++ RT L N PS E R+ + +E+ P P+ N Sbjct: 413 TTSSSAESTEH-----GERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETT 467 Query: 381 -GYHNNLDPMHNYVNTENV----TVPASAHKIEYSRRRDCTPTVFNFDIRRPSLEHRQLN 435 L P+ N E T P+ A E +R P+ EH + Sbjct: 468 ANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPT-EHGERT 526 Query: 436 YIQVDLEGGSDSD----NPQTPKTPTTPLPQTPTRRTELYAVIDIERTAAMSNLQKALPR 491 + + S ++ +T TTP P PT + + + + T +++ + R Sbjct: 527 PLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQR 586 Query: 492 DDGTSRKTRHNSTD 505 + KT +S + Sbjct: 587 TPFANEKTTSSSAE 600 >gi|30061567 La ribonucleoprotein domain family member 2 isoform 1 [Homo sapiens] Length = 914 Score = 32.0 bits (71), Expect = 1.4 Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 10/58 (17%) Query: 451 QTPKTPTTPLPQTPTRRTELYAVIDIERTAAMSNLQKALPRDDGTSRKTRHNSTDLPM 508 +TPKTP TP Q P + Y V+ KA+ RKTRH ST+ P+ Sbjct: 600 RTPKTPRTPRLQDPNKTPRFYPVV---------KEPKAIDVKSPRKRKTRH-STNPPL 647 >gi|10863935 reticulon 1 isoform A [Homo sapiens] Length = 776 Score = 32.0 bits (71), Expect = 1.4 Identities = 33/152 (21%), Positives = 59/152 (38%), Gaps = 23/152 (15%) Query: 119 ERNNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSV 178 + N H T + +P TPG P P S + A V Sbjct: 129 KENGHVT---ISESPEELGTPG-------PSLPDVPGIESRGLFSSDSGIEMTPAESTEV 178 Query: 179 GEESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTPKEEPSSIEDR 238 + PL + + + Y++ T EE K++ H LE ++ +++ Sbjct: 179 NKILADPLDQMKAEAYKYIDITR-PEEVKHQEQHHPELE------------DKDLDFKNK 225 Query: 239 DPQILLEPEGVKFVLGPTPVQKQLMEKEKLEQ 270 D I ++PEGV+ P PV+ ++++ LE+ Sbjct: 226 DTDISIKPEGVREPDKPAPVEGKIIKDHLLEE 257 >gi|5031805 insulin receptor substrate 1 [Homo sapiens] Length = 1242 Score = 31.6 bits (70), Expect = 1.8 Identities = 24/87 (27%), Positives = 33/87 (37%), Gaps = 22/87 (25%) Query: 62 LRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVERN 121 +RR G+ N F E GR TG G F + V++ VV +N Sbjct: 211 IRRCGHSENFFFIEVGRSAVTGPGEFWMQ----------------------VDDSVVAQN 248 Query: 122 NHQTELEVPRTPRTPTTPGFAAQNLPN 148 H+T LE R P +Q+ N Sbjct: 249 MHETILEAMRAMSDEFRPRSKSQSSSN 275 >gi|148612879 polyhomeotic like 3 [Homo sapiens] Length = 995 Score = 31.6 bits (70), Expect = 1.8 Identities = 39/161 (24%), Positives = 61/161 (37%), Gaps = 36/161 (22%) Query: 113 VEEPVVERNNHQTELEVP-------RTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSS 165 V+ PVV + E E+P R RTP P + + G +S Sbjct: 592 VDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVG---------RGEDLTS 642 Query: 166 RHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTTGV----QEERKNRTSVHVPLEARVS 221 HP + LP+V S + + H V + R N TS+H Sbjct: 643 EHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMH-------- 694 Query: 222 NAESSTPKEEPSSIEDRDPQILLEPEGVKFVLGPTPVQKQL 262 SS P SIE++ PQ +++P+ + V+ +Q+ L Sbjct: 695 ---SSIP-----SIENKPPQAIVKPQILTHVIEGFVIQEGL 727 >gi|239755199 PREDICTED: hypothetical protein [Homo sapiens] Length = 279 Score = 31.2 bits (69), Expect = 2.3 Identities = 34/138 (24%), Positives = 52/138 (37%), Gaps = 7/138 (5%) Query: 109 SINVVEEPVVERNNHQTELEVPRTPRTPTT-PGFAAQNLPNGYPRYPSFGDASSHPSSRH 167 SI+ P V + H + P P+ P P+ +P F S HP + H Sbjct: 90 SIHPSIHPPVHLSTHPSTHPSIHPPIHPSIYPSIHLSTHPSIHPPIHPFIHPSIHPPT-H 148 Query: 168 PSVGSARLPSVGEESTHPLLVAEEQVHTYVN-TTGVQEERKNRTSVHVPLEARV--SNAE 224 PS+ ++ P + STHP H ++ T + S+H P + S Sbjct: 149 PSIHASTHPLIHHPSTHP--PTHPSTHPSIHPTIHPRAHPPIHPSIHSPTHPSIHPSTHP 206 Query: 225 SSTPKEEPSSIEDRDPQI 242 S+ P PS+ P I Sbjct: 207 STHPLTHPSTYPSIHPTI 224 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.130 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,066,012 Number of Sequences: 37866 Number of extensions: 1150231 Number of successful extensions: 3935 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 12 Number of HSP's successfully gapped in prelim test: 71 Number of HSP's that attempted gapping in prelim test: 3780 Number of HSP's gapped (non-prelim): 214 length of query: 508 length of database: 18,247,518 effective HSP length: 107 effective length of query: 401 effective length of database: 14,195,856 effective search space: 5692538256 effective search space used: 5692538256 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.