Guide to the Human Genome
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Search of human proteins with 149588660

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|149588660 glutathione S-transferase, C-terminal domain
containing isoform 1 [Homo sapiens]
         (633 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|149588660 glutathione S-transferase, C-terminal domain contai...  1279   0.0  
gi|154707916 glutathione S-transferase, C-terminal domain contai...  1003   0.0  
gi|4758862 eukaryotic translation elongation factor 1 epsilon 1 ...    38   0.025
gi|87299628 biorientation of chromosomes in cell division 1-like...    33   0.61 
gi|110349719 titin isoform N2-A [Homo sapiens]                         33   0.80 
gi|110349717 titin isoform novex-2 [Homo sapiens]                      33   0.80 
gi|110349713 titin isoform novex-1 [Homo sapiens]                      33   0.80 
gi|110349715 titin isoform N2-B [Homo sapiens]                         33   0.80 
gi|8659574 transcription factor E3 [Homo sapiens]                      33   0.80 
gi|33188443 microfilament and actin filament cross-linker protei...    33   1.0  
gi|33188445 microfilament and actin filament cross-linker protei...    33   1.0  
gi|9966827 PEST proteolytic signal containing nuclear protein [H...    32   1.8  
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    31   3.0  
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H...    31   4.0  
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]           31   4.0  
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]           31   4.0  
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]           31   4.0  
gi|90669307 cyclin B3 isoform 3 [Homo sapiens]                         31   4.0  
gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]               31   4.0  
gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]                    31   4.0  
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H...    30   5.2  
gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ...    30   5.2  
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ...    30   5.2  
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]            30   5.2  
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap...    30   5.2  
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap...    30   5.2  
gi|87162461 fragile X mental retardation 2 [Homo sapiens]              30   6.8  
gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]           30   6.8  
gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]    30   8.8  
gi|239751532 PREDICTED: similar to vacuolar protein sorting 53 (...    30   8.8  

>gi|149588660 glutathione S-transferase, C-terminal domain
           containing isoform 1 [Homo sapiens]
          Length = 633

 Score = 1279 bits (3309), Expect = 0.0
 Identities = 633/633 (100%), Positives = 633/633 (100%)

Query: 1   MKAIKKSLTEEEYLYLDFSHQTEGCIFPLHTSVTLFLLSYCDCKIFKICLVVTKEVSRDS 60
           MKAIKKSLTEEEYLYLDFSHQTEGCIFPLHTSVTLFLLSYCDCKIFKICLVVTKEVSRDS
Sbjct: 1   MKAIKKSLTEEEYLYLDFSHQTEGCIFPLHTSVTLFLLSYCDCKIFKICLVVTKEVSRDS 60

Query: 61  SLLRDDLIQDVEIQIISRQELPPIVQNCCLPAVVERSDNFCRAGLAVVLRHIIQKSYEAD 120
           SLLRDDLIQDVEIQIISRQELPPIVQNCCLPAVVERSDNFCRAGLAVVLRHIIQKSYEAD
Sbjct: 61  SLLRDDLIQDVEIQIISRQELPPIVQNCCLPAVVERSDNFCRAGLAVVLRHIIQKSYEAD 120

Query: 121 PLKKELLELLGFKKTCLKACAEVSQWTRLCELTIPLAIENFLRESSDQPPTIPVEILQLE 180
           PLKKELLELLGFKKTCLKACAEVSQWTRLCELTIPLAIENFLRESSDQPPTIPVEILQLE
Sbjct: 121 PLKKELLELLGFKKTCLKACAEVSQWTRLCELTIPLAIENFLRESSDQPPTIPVEILQLE 180

Query: 181 KKLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELK 240
           KKLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELK
Sbjct: 181 KKLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELK 240

Query: 241 VAFSKLTVQEEPATTNREPSHIRKAKASDLPPLEHVFAEGLYFTLADIVLLPCIHHFLVI 300
           VAFSKLTVQEEPATTNREPSHIRKAKASDLPPLEHVFAEGLYFTLADIVLLPCIHHFLVI
Sbjct: 241 VAFSKLTVQEEPATTNREPSHIRKAKASDLPPLEHVFAEGLYFTLADIVLLPCIHHFLVI 300

Query: 301 ISRKFSEKLVEFPLLASWYQRIQEVPGVKTAASKCGIQFLHLPKLLTTSTEQHPNLCEVP 360
           ISRKFSEKLVEFPLLASWYQRIQEVPGVKTAASKCGIQFLHLPKLLTTSTEQHPNLCEVP
Sbjct: 301 ISRKFSEKLVEFPLLASWYQRIQEVPGVKTAASKCGIQFLHLPKLLTTSTEQHPNLCEVP 360

Query: 361 GVEEQSDPLFIGGPRPTMAKLMEKGIEVMFSPHPCPTWTLDWNVLPAAVSPKEGKMSSDR 420
           GVEEQSDPLFIGGPRPTMAKLMEKGIEVMFSPHPCPTWTLDWNVLPAAVSPKEGKMSSDR
Sbjct: 361 GVEEQSDPLFIGGPRPTMAKLMEKGIEVMFSPHPCPTWTLDWNVLPAAVSPKEGKMSSDR 420

Query: 421 ALRKQQQLNNLVYVVTNQAKPGDRIVDFCSGGGHVGIVLAHMLPSCQVTLIENKELSLIR 480
           ALRKQQQLNNLVYVVTNQAKPGDRIVDFCSGGGHVGIVLAHMLPSCQVTLIENKELSLIR
Sbjct: 421 ALRKQQQLNNLVYVVTNQAKPGDRIVDFCSGGGHVGIVLAHMLPSCQVTLIENKELSLIR 480

Query: 481 AKKRSDELGLSNIWFIQANMEYFTGMFNIGVALHACGVATDMVIEHCIKTRASFVTCPCC 540
           AKKRSDELGLSNIWFIQANMEYFTGMFNIGVALHACGVATDMVIEHCIKTRASFVTCPCC
Sbjct: 481 AKKRSDELGLSNIWFIQANMEYFTGMFNIGVALHACGVATDMVIEHCIKTRASFVTCPCC 540

Query: 541 YGFIQNTSKFNFPKSEQFKKTLSYKEHMILCRFADQTAVQLPPQRRLIGKQCMCLVDLDR 600
           YGFIQNTSKFNFPKSEQFKKTLSYKEHMILCRFADQTAVQLPPQRRLIGKQCMCLVDLDR
Sbjct: 541 YGFIQNTSKFNFPKSEQFKKTLSYKEHMILCRFADQTAVQLPPQRRLIGKQCMCLVDLDR 600

Query: 601 ARAAEECGYSVQVISMEPESCSPKNNMIVGVPI 633
           ARAAEECGYSVQVISMEPESCSPKNNMIVGVPI
Sbjct: 601 ARAAEECGYSVQVISMEPESCSPKNNMIVGVPI 633


>gi|154707916 glutathione S-transferase, C-terminal domain
           containing isoform 2 [Homo sapiens]
          Length = 546

 Score = 1003 bits (2594), Expect = 0.0
 Identities = 495/500 (99%), Positives = 495/500 (99%)

Query: 134 KTCLKACAEVSQWTRLCELTIPLAIENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDD 193
           K CL    EVSQWTRLCELTIPLAIENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDD
Sbjct: 47  KICLVVTKEVSQWTRLCELTIPLAIENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDD 106

Query: 194 KLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEEPA 253
           KLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEEPA
Sbjct: 107 KLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEEPA 166

Query: 254 TTNREPSHIRKAKASDLPPLEHVFAEGLYFTLADIVLLPCIHHFLVIISRKFSEKLVEFP 313
           TTNREPSHIRKAKASDLPPLEHVFAEGLYFTLADIVLLPCIHHFLVIISRKFSEKLVEFP
Sbjct: 167 TTNREPSHIRKAKASDLPPLEHVFAEGLYFTLADIVLLPCIHHFLVIISRKFSEKLVEFP 226

Query: 314 LLASWYQRIQEVPGVKTAASKCGIQFLHLPKLLTTSTEQHPNLCEVPGVEEQSDPLFIGG 373
           LLASWYQRIQEVPGVKTAASKCGIQFLHLPKLLTTSTEQHPNLCEVPGVEEQSDPLFIGG
Sbjct: 227 LLASWYQRIQEVPGVKTAASKCGIQFLHLPKLLTTSTEQHPNLCEVPGVEEQSDPLFIGG 286

Query: 374 PRPTMAKLMEKGIEVMFSPHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVY 433
           PRPTMAKLMEKGIEVMFSPHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVY
Sbjct: 287 PRPTMAKLMEKGIEVMFSPHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVY 346

Query: 434 VVTNQAKPGDRIVDFCSGGGHVGIVLAHMLPSCQVTLIENKELSLIRAKKRSDELGLSNI 493
           VVTNQAKPGDRIVDFCSGGGHVGIVLAHMLPSCQVTLIENKELSLIRAKKRSDELGLSNI
Sbjct: 347 VVTNQAKPGDRIVDFCSGGGHVGIVLAHMLPSCQVTLIENKELSLIRAKKRSDELGLSNI 406

Query: 494 WFIQANMEYFTGMFNIGVALHACGVATDMVIEHCIKTRASFVTCPCCYGFIQNTSKFNFP 553
           WFIQANMEYFTGMFNIGVALHACGVATDMVIEHCIKTRASFVTCPCCYGFIQNTSKFNFP
Sbjct: 407 WFIQANMEYFTGMFNIGVALHACGVATDMVIEHCIKTRASFVTCPCCYGFIQNTSKFNFP 466

Query: 554 KSEQFKKTLSYKEHMILCRFADQTAVQLPPQRRLIGKQCMCLVDLDRARAAEECGYSVQV 613
           KSEQFKKTLSYKEHMILCRFADQTAVQLPPQRRLIGKQCMCLVDLDRARAAEECGYSVQV
Sbjct: 467 KSEQFKKTLSYKEHMILCRFADQTAVQLPPQRRLIGKQCMCLVDLDRARAAEECGYSVQV 526

Query: 614 ISMEPESCSPKNNMIVGVPI 633
           ISMEPESCSPKNNMIVGVPI
Sbjct: 527 ISMEPESCSPKNNMIVGVPI 546



 Score =  122 bits (306), Expect = 1e-27
 Identities = 61/85 (71%), Positives = 68/85 (80%)

Query: 1  MKAIKKSLTEEEYLYLDFSHQTEGCIFPLHTSVTLFLLSYCDCKIFKICLVVTKEVSRDS 60
          MKAIKKSLTEEEYLYLDFSHQTEGCIFPLHTSVTLFLLSYCDCKIFKICLVVTKEVS+ +
Sbjct: 1  MKAIKKSLTEEEYLYLDFSHQTEGCIFPLHTSVTLFLLSYCDCKIFKICLVVTKEVSQWT 60

Query: 61 SLLRDDLIQDVEIQIISRQELPPIV 85
           L    +   +E  +    + PP +
Sbjct: 61 RLCELTIPLAIENFLRESSDQPPTI 85


>gi|4758862 eukaryotic translation elongation factor 1 epsilon 1
           isoform 1 [Homo sapiens]
          Length = 174

 Score = 38.1 bits (87), Expect = 0.025
 Identities = 19/56 (33%), Positives = 33/56 (58%), Gaps = 3/56 (5%)

Query: 274 EHVFAEGLYFTLADIVLLPCIHHFLVIISRKFSEKLVEFPLLASWYQRIQEVPGVK 329
           + V+  G  FTLADI+L   +H F+V ++ +  EK +    ++ W+  IQ  PG++
Sbjct: 104 DKVYLTGYNFTLADILLYYGLHRFIVDLTVQEKEKYLN---VSRWFCHIQHYPGIR 156


>gi|87299628 biorientation of chromosomes in cell division 1-like
           [Homo sapiens]
          Length = 3051

 Score = 33.5 bits (75), Expect = 0.61
 Identities = 34/141 (24%), Positives = 58/141 (41%), Gaps = 27/141 (19%)

Query: 166 SDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTKGKAKSKVHTQE 225
           SD   T+      + K+  E +     ++ + ++ ++QKA+      TKG+ +S V  +E
Sbjct: 484 SDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEE 543

Query: 226 TS-EGLDSSS----------KSLELKVAFS----------------KLTVQEEPATTNRE 258
           +S + L+  +          K LE KVA S                K   +E+   T + 
Sbjct: 544 SSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKT 603

Query: 259 PSHIRKAKASDLPPLEHVFAE 279
             H  K K S    L+HV A+
Sbjct: 604 SEHCEKEKISSSKELKHVHAK 624


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 33.1 bits (74), Expect = 0.80
 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 7/85 (8%)

Query: 392   PHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVYVVTNQAKPGDR----IVD 447
             P P  TW ++   LP   + +   +SS   ++  Q+ +  VY +  + + G+R    IVD
Sbjct: 16552 PPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVD 16611

Query: 448   FCSGGGHVGI-VLAHML--PSCQVT 469
                  G VG   LAH L   SC++T
Sbjct: 16612 VLDVPGPVGTPFLAHNLTNESCKLT 16636


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 33.1 bits (74), Expect = 0.80
 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 7/85 (8%)

Query: 392   PHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVYVVTNQAKPGDR----IVD 447
             P P  TW ++   LP   + +   +SS   ++  Q+ +  VY +  + + G+R    IVD
Sbjct: 10247 PPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVD 10306

Query: 448   FCSGGGHVGI-VLAHML--PSCQVT 469
                  G VG   LAH L   SC++T
Sbjct: 10307 VLDVPGPVGTPFLAHNLTNESCKLT 10331


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 33.1 bits (74), Expect = 0.80
 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 7/85 (8%)

Query: 392   PHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVYVVTNQAKPGDR----IVD 447
             P P  TW ++   LP   + +   +SS   ++  Q+ +  VY +  + + G+R    IVD
Sbjct: 10180 PPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVD 10239

Query: 448   FCSGGGHVGI-VLAHML--PSCQVT 469
                  G VG   LAH L   SC++T
Sbjct: 10240 VLDVPGPVGTPFLAHNLTNESCKLT 10264


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 33.1 bits (74), Expect = 0.80
 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 7/85 (8%)

Query: 392   PHPCPTWTLDWNVLPAAVSPKEGKMSSDRALRKQQQLNNLVYVVTNQAKPGDR----IVD 447
             P P  TW ++   LP   + +   +SS   ++  Q+ +  VY +  + + G+R    IVD
Sbjct: 10055 PPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVD 10114

Query: 448   FCSGGGHVGI-VLAHML--PSCQVT 469
                  G VG   LAH L   SC++T
Sbjct: 10115 VLDVPGPVGTPFLAHNLTNESCKLT 10139


>gi|8659574 transcription factor E3 [Homo sapiens]
          Length = 575

 Score = 33.1 bits (74), Expect = 0.80
 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 1/48 (2%)

Query: 165 SSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADGVGPPL 212
           S   P  +P E+L+++  L  P R H   + RRQ++KQ  +  +GP L
Sbjct: 165 SRPPPAQVPREVLKVQTHLENPTRYHL-QQARRQQVKQYLSTTLGPKL 211


>gi|33188443 microfilament and actin filament cross-linker protein
            isoform b [Homo sapiens]
          Length = 5938

 Score = 32.7 bits (73), Expect = 1.0
 Identities = 30/121 (24%), Positives = 48/121 (39%), Gaps = 9/121 (7%)

Query: 122  LKKELLELLGFKKTCLKACAEVSQWTRLCELTIPLAIENFLRESSDQPPTIPVEILQLEK 181
            L   L  LLG       +   +  W + CE  +    E  L ++    P +  E L   K
Sbjct: 2425 LGSHLNMLLGQYHQFQNSADSLQAWMQACEANV----EKLLSDTVASDPGVLQEQLATTK 2480

Query: 182  KLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKV 241
            +L E +  H     + QK+ +   +  G P     A    H QET++ + S  +SL   +
Sbjct: 2481 QLQEELAEHQVPVEKLQKVARDIMEIEGEP-----APDHRHVQETTDSILSHFQSLSYSL 2535

Query: 242  A 242
            A
Sbjct: 2536 A 2536


>gi|33188445 microfilament and actin filament cross-linker protein
            isoform a [Homo sapiens]
          Length = 5430

 Score = 32.7 bits (73), Expect = 1.0
 Identities = 30/121 (24%), Positives = 48/121 (39%), Gaps = 9/121 (7%)

Query: 122  LKKELLELLGFKKTCLKACAEVSQWTRLCELTIPLAIENFLRESSDQPPTIPVEILQLEK 181
            L   L  LLG       +   +  W + CE  +    E  L ++    P +  E L   K
Sbjct: 1923 LGSHLNMLLGQYHQFQNSADSLQAWMQACEANV----EKLLSDTVASDPGVLQEQLATTK 1978

Query: 182  KLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKV 241
            +L E +  H     + QK+ +   +  G P     A    H QET++ + S  +SL   +
Sbjct: 1979 QLQEELAEHQVPVEKLQKVARDIMEIEGEP-----APDHRHVQETTDSILSHFQSLSYSL 2033

Query: 242  A 242
            A
Sbjct: 2034 A 2034


>gi|9966827 PEST proteolytic signal containing nuclear protein [Homo
           sapiens]
          Length = 178

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 6/64 (9%)

Query: 201 KQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEEPATTNREPS 260
           K Q+A   G P  + +   K  T  +S G +SSS+S E      K + +EE A    +P+
Sbjct: 13  KSQRAGAAGGPEEEAEKPVKTKTVSSSNGGESSSRSAE------KRSAEEEAADLPTKPT 66

Query: 261 HIRK 264
            I K
Sbjct: 67  KISK 70


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein
           [Homo sapiens]
          Length = 3969

 Score = 31.2 bits (69), Expect = 3.0
 Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 7/88 (7%)

Query: 193 DKLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEEP 252
           DK++++  K  +     PP   G      H ++ SE L   +K   LK       ++  P
Sbjct: 208 DKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISE-LPKGNKEDSLK------KIKRTP 260

Query: 253 ATTNREPSHIRKAKASDLPPLEHVFAEG 280
           + T ++ + I+K +A  L PL+  F  G
Sbjct: 261 SATFQQATKIKKLRAGKLSPLKSKFKTG 288


>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
           sapiens]
          Length = 1094

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 40/137 (29%), Positives = 62/137 (45%), Gaps = 25/137 (18%)

Query: 44  KIFKICLVVTKEVSRDSSLLR-----------DDLIQDVEIQIISRQELPPIVQNCCLPA 92
           K+  + LV   E  +D +LL            + LI+   ++++S   +P IV    L A
Sbjct: 96  KLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMML-A 154

Query: 93  VVERSDNFCRAGLAVVLR----HIIQKSYEADPLKKELL----ELLGFKKTCLKACAEVS 144
           + E S     A L+  +R    H IQK Y  DP +KE+L    E L   K+ L A + V 
Sbjct: 155 IKEAS-----ADLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLKDKSTLVAGSVVM 209

Query: 145 QWTRLCELTIPLAIENF 161
            +  +C   I L  +N+
Sbjct: 210 AFEEVCPDRIDLIHKNY 226


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 44/185 (23%), Positives = 78/185 (42%), Gaps = 11/185 (5%)

Query: 92   AVVERSDNFCRAGLAVVLRHIIQKSYEADPLKKELLELLGFKKTCLKAC----AEVSQWT 147
            A VER +   +  LAV  R  ++   E + LK ++      K+  +K      A++ +  
Sbjct: 1626 AEVERDEERKQRTLAVAARKKLEG--ELEELKAQMASAGQGKEEAVKQLRKMQAQMKELW 1683

Query: 148  RLCELTIPLAIENFL--RESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKA 205
            R  E T     E F   RES  +   +  E+L+L+++L+   R     +  R ++  + A
Sbjct: 1684 REVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVA 1743

Query: 206  DG--VGPPLTKGKAKSKVHTQETSEGLDSSSKSLE-LKVAFSKLTVQEEPATTNREPSHI 262
            +G      + + K + +    +  E L+    + E L   + KL +Q E  TT       
Sbjct: 1744 NGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERS 1803

Query: 263  RKAKA 267
              AKA
Sbjct: 1804 FSAKA 1808


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 44/185 (23%), Positives = 78/185 (42%), Gaps = 11/185 (5%)

Query: 92   AVVERSDNFCRAGLAVVLRHIIQKSYEADPLKKELLELLGFKKTCLKAC----AEVSQWT 147
            A VER +   +  LAV  R  ++   E + LK ++      K+  +K      A++ +  
Sbjct: 1618 AEVERDEERKQRTLAVAARKKLEG--ELEELKAQMASAGQGKEEAVKQLRKMQAQMKELW 1675

Query: 148  RLCELTIPLAIENFL--RESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKA 205
            R  E T     E F   RES  +   +  E+L+L+++L+   R     +  R ++  + A
Sbjct: 1676 REVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVA 1735

Query: 206  DG--VGPPLTKGKAKSKVHTQETSEGLDSSSKSLE-LKVAFSKLTVQEEPATTNREPSHI 262
            +G      + + K + +    +  E L+    + E L   + KL +Q E  TT       
Sbjct: 1736 NGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERS 1795

Query: 263  RKAKA 267
              AKA
Sbjct: 1796 FSAKA 1800


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 44/185 (23%), Positives = 78/185 (42%), Gaps = 11/185 (5%)

Query: 92   AVVERSDNFCRAGLAVVLRHIIQKSYEADPLKKELLELLGFKKTCLKAC----AEVSQWT 147
            A VER +   +  LAV  R  ++   E + LK ++      K+  +K      A++ +  
Sbjct: 1659 AEVERDEERKQRTLAVAARKKLEG--ELEELKAQMASAGQGKEEAVKQLRKMQAQMKELW 1716

Query: 148  RLCELTIPLAIENFL--RESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKA 205
            R  E T     E F   RES  +   +  E+L+L+++L+   R     +  R ++  + A
Sbjct: 1717 REVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVA 1776

Query: 206  DG--VGPPLTKGKAKSKVHTQETSEGLDSSSKSLE-LKVAFSKLTVQEEPATTNREPSHI 262
            +G      + + K + +    +  E L+    + E L   + KL +Q E  TT       
Sbjct: 1777 NGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERS 1836

Query: 263  RKAKA 267
              AKA
Sbjct: 1837 FSAKA 1841


>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
          Length = 1395

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 57/242 (23%), Positives = 97/242 (40%), Gaps = 30/242 (12%)

Query: 1   MKAIKKSLTEEEYLYLDFS-----HQTEGCIFPLHTSVTLFLLSYCDCKIFKICLVVTKE 55
           M +IKK  TE+E L+ + S     H TE  +  L  S+ L   ++ +  + K  L   K+
Sbjct: 313 MSSIKKPTTEKETLFQELSVLQEKHTTEHEMSILKKSLALQKTNFKEDSLVKESLAFKKK 372

Query: 56  VSRDSSLLRDDLIQDVEIQIISRQELPPIVQNCCLPAVVERSDNFCRAGLAVVLRHIIQK 115
            S + +++   ++++  +    R  L P+V    L  +     +     L++  +   +K
Sbjct: 373 PSTEEAIMMPVILKEQCMTEGKRSRLKPLV----LQEITSGEKSLIMKPLSIKEKPSTEK 428

Query: 116 ---SYEADPLKK-----ELLELLGFKKTCLKACAEVSQWTRLCELTIPLAIENFLRESSD 167
              S E   L+K     E + +L    + LK+  E S +      T    IE       +
Sbjct: 429 ESFSQEPSALQKKHTTQEEVSILKEPSSLLKSPTEESPFDEALAFTKKCTIE-------E 481

Query: 168 QPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADGVGPPL----TKGKAKSKVHT 223
            PPT    IL+  K  ++    H    L  Q    +K+  +  PL     K   K K  T
Sbjct: 482 APPTKKPLILK-RKHATQGTMSHLKKPLILQTTSGEKS-LIKEPLPFKEEKVSLKKKCTT 539

Query: 224 QE 225
           QE
Sbjct: 540 QE 541


>gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]
          Length = 1910

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 30/132 (22%), Positives = 53/132 (40%), Gaps = 25/132 (18%)

Query: 158  IENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTKGKA 217
            + +F ++ SDQ    PV+ ++  K L                L    ++ + P   KG A
Sbjct: 1043 VHSFQQDKSDQRENSPVQSIRSPKSL----------------LFGAMSEMISPS-EKGSA 1085

Query: 218  KSKVHTQETSE-----GLDSSSKSLELKVAFSKLT---VQEEPATTNREPSHIRKAKASD 269
            + K  ++ T +        +  KS +  ++FSK T   +   P T    P  ++K+ A  
Sbjct: 1086 RMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKM 1145

Query: 270  LPPLEHVFAEGL 281
             P  +  F E L
Sbjct: 1146 TPTKQAAFKESL 1157


>gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]
          Length = 1858

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 3/49 (6%)

Query: 165  SSDQPPTIPVEILQL---EKKLSEPVRVHNDDKLRRQKLKQQKADGVGP 210
            +SD+ P  P+E+ +L   E  L  PV+      L  Q  K QK DG  P
Sbjct: 1505 ASDESPLTPLEVKKLPVLETNLKYPVQPEGSSPLSPQYSKSQKGDGDRP 1553


>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
           sapiens]
          Length = 1082

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 12/84 (14%)

Query: 191 NDDKLRRQKLKQQKADGVGPPLTKGKAKSKV-----HTQETSEGLDSSSKSLELKVAFSK 245
           +++K R  + +Q + DG      K K K KV         + EG DSSS S E ++    
Sbjct: 726 DEEKGRGSESEQSEEDG------KRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSES 779

Query: 246 LTVQEEPATTNRE-PSHIRKAKAS 268
              Q EPA+ +R+ P   + A A+
Sbjct: 780 EEEQLEPASWSRKTPPSSKSAPAT 803


>gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo
            sapiens]
          Length = 2155

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 34/135 (25%), Positives = 65/135 (48%), Gaps = 18/135 (13%)

Query: 43   CKIFKICLVVTKEVSRDSSLLRDDLI--QDVEIQIISRQELPPIVQNCCL---------P 91
            C+  ++ LV T +  R  S++RD ++  +DV I+ I  QE P  V +  L          
Sbjct: 1887 CESRRVRLVDTGDKFRFFSMVRDLMLWMEDV-IRQIEAQEKPRDVSSVELLMNNHQGIKA 1945

Query: 92   AVVERSDNFCRAGLAVVLRHIIQKSYEADPLKKELLELLGFKKTCLKACAEVSQWTRLCE 151
             +  R+D+F    + +    + +K Y ++ +K++LL+L   +K  +    +  +W RL  
Sbjct: 1946 EIDARNDSFTTC-IELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLI- 2003

Query: 152  LTIPLAIENFLRESS 166
                L +  F R++S
Sbjct: 2004 ----LEVHQFSRDAS 2014


>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
            sapiens]
          Length = 2364

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 34/135 (25%), Positives = 65/135 (48%), Gaps = 18/135 (13%)

Query: 43   CKIFKICLVVTKEVSRDSSLLRDDLI--QDVEIQIISRQELPPIVQNCCL---------P 91
            C+  ++ LV T +  R  S++RD ++  +DV I+ I  QE P  V +  L          
Sbjct: 1900 CESRRVRLVDTGDKFRFFSMVRDLMLWMEDV-IRQIEAQEKPRDVSSVELLMNNHQGIKA 1958

Query: 92   AVVERSDNFCRAGLAVVLRHIIQKSYEADPLKKELLELLGFKKTCLKACAEVSQWTRLCE 151
             +  R+D+F    + +    + +K Y ++ +K++LL+L   +K  +    +  +W RL  
Sbjct: 1959 EIDARNDSFTTC-IELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLI- 2016

Query: 152  LTIPLAIENFLRESS 166
                L +  F R++S
Sbjct: 2017 ----LEVHQFSRDAS 2027


>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
          Length = 4523

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 22/77 (28%), Positives = 40/77 (51%), Gaps = 6/77 (7%)

Query: 398  WTLDWNVLPAAVSPKEGKMSSDRALRKQQ--QLNNLVYVVTNQAKPGDR--IVDFCSGGG 453
            WT D  +  + +  +EG  ++ +   K+Q  QLN L+ ++  +  PGDR  I+  C+   
Sbjct: 1755 WTTDVGIAFSRL--EEGYETALKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDV 1812

Query: 454  HVGIVLAHMLPSCQVTL 470
            H   V+A ++   QV +
Sbjct: 1813 HARDVVAKLISQKQVVV 1829


>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
          Length = 1758

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 7/88 (7%)

Query: 163  RESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTKGKAKSKVH 222
            + + +   T PV+  +++K  S+ V+    +KL  ++ K +K +    PL     K K  
Sbjct: 1060 KSAKEHQETKPVKEEKVKKDYSKDVK---SEKLTTKEEKAKKPNEKNKPLDNKGEKRKRK 1116

Query: 223  TQETSEGLDSSSKSLELKVAFSKLTVQE 250
            T+E  +G+D   +S  +K+  SKL V E
Sbjct: 1117 TEE--KGVDKDFESSSMKI--SKLEVTE 1140


>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
          Length = 1792

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 7/88 (7%)

Query: 163  RESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTKGKAKSKVH 222
            + + +   T PV+  +++K  S+ V+    +KL  ++ K +K +    PL     K K  
Sbjct: 1094 KSAKEHQETKPVKEEKVKKDYSKDVK---SEKLTTKEEKAKKPNEKNKPLDNKGEKRKRK 1150

Query: 223  TQETSEGLDSSSKSLELKVAFSKLTVQE 250
            T+E  +G+D   +S  +K+  SKL V E
Sbjct: 1151 TEE--KGVDKDFESSSMKI--SKLEVTE 1174


>gi|87162461 fragile X mental retardation 2 [Homo sapiens]
          Length = 1311

 Score = 30.0 bits (66), Expect = 6.8
 Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 5/105 (4%)

Query: 158 IENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTK--- 214
           +E+ L+ SSD+    PV+ L  +   +E  +     K R   +    A    PP  +   
Sbjct: 423 LEDDLKLSSDEDDLEPVKTLTTQCTATELYQAVEKAKPRNNPVNPPLATPQPPPAVQASG 482

Query: 215 --GKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEEPATTNR 257
             G +     + E+    +SS+   E   A    T + EP +TN+
Sbjct: 483 GSGSSSESESSSESDSDTESSTTDSESNEAPRVATPEPEPPSTNK 527


>gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]
          Length = 5120

 Score = 30.0 bits (66), Expect = 6.8
 Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 3/102 (2%)

Query: 151  ELTIPLAIENFLRESSDQPPTIPVEILQLEKKLSEPVRVHNDDKL-RRQKLKQQKADGVG 209
            +LT    I+  LRE   +      + +Q +K   E  R   +D+L RR K  +Q      
Sbjct: 2314 KLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEE 2373

Query: 210  PPLTKGKAKSKVHTQETSEGLDSSSKSLELKVAFSKLTVQEE 251
            PP+ K +A +K     T   +D   +++E K++  + T+ E+
Sbjct: 2374 PPMKKSQAANKQVPPLTK--VDVKMETIERKISVREQTMSEK 2413


>gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]
          Length = 1162

 Score = 29.6 bits (65), Expect = 8.8
 Identities = 16/64 (25%), Positives = 31/64 (48%), Gaps = 7/64 (10%)

Query: 123 KKELLELLGFKKTCLKACAEVSQWTRL----CELTIPLAIENFLRESSDQPPTIPVEILQ 178
           ++EL E +   KT  K C +   WT++    C+  +P A+   ++    QP ++ +    
Sbjct: 907 RRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKR---QPVSLDLSWTN 963

Query: 179 LEKK 182
           + KK
Sbjct: 964 ISKK 967


>gi|239751532 PREDICTED: similar to vacuolar protein sorting 53
           (yeast) (predicted) [Homo sapiens]
          Length = 188

 Score = 29.6 bits (65), Expect = 8.8
 Identities = 28/118 (23%), Positives = 49/118 (41%), Gaps = 8/118 (6%)

Query: 252 PATTNREPSHIRKAKASDLPPLEHVFAEGLY---FTLADIVLLPCIHHFLVIISRKFSEK 308
           P    RE  HI              F +G+    + LA++V  P     LV++   + + 
Sbjct: 10  PKLLEREQRHISSPGLPSGIAAPDPFGKGIQRCRWLLAEVVTAP--QELLVVLVDNYIKL 67

Query: 309 LVEFPLLASWYQRIQEVPGVKTAASKCGIQFLHLP-KLLTTSTEQHPNLCEVPGVEEQ 365
             +    A  +++I ++ G+K       ++FLHLP  +L    E   +L  +P   EQ
Sbjct: 68  FTDCNTEA--FRKILDMKGMKRNKQSSMLEFLHLPLPMLPLGVESSSSLSLMPPTPEQ 123


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,757,997
Number of Sequences: 37866
Number of extensions: 1105976
Number of successful extensions: 2863
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 2841
Number of HSP's gapped (non-prelim): 49
length of query: 633
length of database: 18,247,518
effective HSP length: 108
effective length of query: 525
effective length of database: 14,157,990
effective search space: 7432944750
effective search space used: 7432944750
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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