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Search of human proteins with 149363679
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
(823 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 1622 0.0
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 1605 0.0
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 1605 0.0
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 1599 0.0
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 1420 0.0
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 1420 0.0
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] 470 e-132
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo... 470 e-132
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo... 467 e-131
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 378 e-104
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 378 e-104
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 377 e-104
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens] 374 e-103
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 368 e-101
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 368 e-101
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 368 e-101
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 320 3e-87
gi|115495445 ankyrin repeat domain 30A [Homo sapiens] 281 2e-75
gi|153791352 prostate, ovary, testis expressed protein on chromo... 271 2e-72
gi|134133226 protein expressed in prostate, ovary, testis, and p... 271 2e-72
gi|222537750 ankyrin repeat domain 30B [Homo sapiens] 270 5e-72
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 268 2e-71
gi|88953571 PREDICTED: similar to protein expressed in prostate,... 266 8e-71
gi|113413200 PREDICTED: similar to protein expressed in prostate... 265 1e-70
gi|239741769 PREDICTED: similar to protein expressed in prostate... 248 2e-65
gi|239741786 PREDICTED: kappa-actin [Homo sapiens] 245 1e-64
gi|239753333 PREDICTED: actin, beta-like 3 [Homo sapiens] 245 1e-64
gi|239747898 PREDICTED: actin, beta-like 3 [Homo sapiens] 245 1e-64
gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo... 241 3e-63
gi|52856430 protein expressed in prostate, ovary, testis, and pl... 234 3e-61
>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
Length = 823
Score = 1622 bits (4201), Expect = 0.0
Identities = 823/823 (100%), Positives = 823/823 (100%)
Query: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGEL 60
MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGEL
Sbjct: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGEL 60
Query: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120
DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL
Sbjct: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120
Query: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180
EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK
Sbjct: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180
Query: 181 MVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240
MVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI
Sbjct: 181 MVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240
Query: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300
SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC
Sbjct: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300
Query: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360
VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA
Sbjct: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360
Query: 361 EQALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
EQALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK
Sbjct: 361 EQALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
Query: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480
IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE
Sbjct: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480
Query: 481 PTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540
PTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN
Sbjct: 481 PTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540
Query: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKK 600
KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKK
Sbjct: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKK 600
Query: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFL 660
RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFL
Sbjct: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFL 660
Query: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKV 720
TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKV
Sbjct: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKV 720
Query: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDFVLEE 780
NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDFVLEE
Sbjct: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDFVLEE 780
Query: 781 KSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYFQTSRKKI 823
KSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYFQTSRKKI
Sbjct: 781 KSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYFQTSRKKI 823
>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo
sapiens]
Length = 823
Score = 1605 bits (4156), Expect = 0.0
Identities = 815/823 (99%), Positives = 820/823 (99%)
Query: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGEL 60
MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSG+L
Sbjct: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDL 60
Query: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120
DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL
Sbjct: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120
Query: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180
EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK
Sbjct: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180
Query: 181 MVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240
MVEFLLK+KASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI
Sbjct: 181 MVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240
Query: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300
SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC
Sbjct: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300
Query: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360
VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA
Sbjct: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360
Query: 361 EQALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
EQALPVASEEEQ+RHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK
Sbjct: 361 EQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
Query: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480
IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE
Sbjct: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480
Query: 481 PTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540
PTVQSLEMKSKTARNTPN DFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN
Sbjct: 481 PTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540
Query: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKK 600
KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKK
Sbjct: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKK 600
Query: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFL 660
RLEADIESYQSRLAAAISKHSESVKTERNLKLALERT+DVSVQVEMSSAISKVKDENEFL
Sbjct: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFL 660
Query: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKV 720
TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQN+LSQTQQQTQEMKEMYQNAEAKV
Sbjct: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKV 720
Query: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDFVLEE 780
NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKD VLEE
Sbjct: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEE 780
Query: 781 KSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYFQTSRKKI 823
KSKKLMNECDHLKESLFQYEREKTE VVSIKEDKYFQTSRKKI
Sbjct: 781 KSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRKKI 823
>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
sapiens]
Length = 823
Score = 1605 bits (4155), Expect = 0.0
Identities = 814/823 (98%), Positives = 818/823 (99%)
Query: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGEL 60
MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSG+L
Sbjct: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDL 60
Query: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120
DALDKQHRTALHLAC SGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL
Sbjct: 61 DALDKQHRTALHLACTSGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120
Query: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180
EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK
Sbjct: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180
Query: 181 MVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240
MVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI
Sbjct: 181 MVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240
Query: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300
SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC
Sbjct: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300
Query: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360
VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA
Sbjct: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360
Query: 361 EQALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
EQALPVASEEEQ+RHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK
Sbjct: 361 EQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
Query: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480
IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE
Sbjct: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480
Query: 481 PTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540
PTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN
Sbjct: 481 PTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540
Query: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKK 600
KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKK
Sbjct: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKK 600
Query: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFL 660
RLEADIESYQSRLAAAISKHSESVKTERNLKLALERT+DVSVQVEMSSAISKVK ENEFL
Sbjct: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKAENEFL 660
Query: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKV 720
TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQN+LSQTQQQTQEMKEMYQNAEAKV
Sbjct: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKV 720
Query: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDFVLEE 780
NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKD VLEE
Sbjct: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEE 780
Query: 781 KSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYFQTSRKKI 823
KSKKLMNECDHLKESLFQYEREKTE VVSIKEDKYFQTSRK I
Sbjct: 781 KSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRKTI 823
>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo
sapiens]
Length = 823
Score = 1599 bits (4141), Expect = 0.0
Identities = 813/823 (98%), Positives = 818/823 (99%)
Query: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGEL 60
MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSG+L
Sbjct: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDL 60
Query: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120
DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL
Sbjct: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120
Query: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180
EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK
Sbjct: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180
Query: 181 MVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240
MVEFLLK+KASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI
Sbjct: 181 MVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240
Query: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300
SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC
Sbjct: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300
Query: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360
VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA
Sbjct: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360
Query: 361 EQALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
EQALPVASEEEQ+RHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK
Sbjct: 361 EQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
Query: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480
IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE
Sbjct: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480
Query: 481 PTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540
PTVQSLEMKSKTARNTPN DFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN
Sbjct: 481 PTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540
Query: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKK 600
KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELN LKAENTRLNAELLKEKESKK
Sbjct: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKK 600
Query: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFL 660
RLEADIESYQSRLAAAISKHSESVKTERNLKLALERT+DVSVQVEMSSAISKVKDENEFL
Sbjct: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFL 660
Query: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKV 720
TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQN+LSQTQQQTQEMKEMYQNAEAKV
Sbjct: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKV 720
Query: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDFVLEE 780
NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKD VLEE
Sbjct: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEE 780
Query: 781 KSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYFQTSRKKI 823
KSKKLMNECDHLKESLFQYEREKTE VVSIKEDKYFQTSRK I
Sbjct: 781 KSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRKTI 823
>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 1420 bits (3676), Expect = 0.0
Identities = 727/823 (88%), Positives = 768/823 (93%)
Query: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGEL 60
MKLFGF SRRGQT GSIDH+YTGSGYRIR SELQKIH+AAVKGDAAE+ERCLARRSG+L
Sbjct: 1 MKLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDL 60
Query: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120
DALDKQHRTALHLACASGHV+VVTLLVNRKCQID+ DKENRTPLIQAVHCQEEACAVILL
Sbjct: 61 DALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILL 120
Query: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180
EHGANPNLKDIYGNTALHYAVYSESTSLAEKLL HG +IEALDKD+NTPLLFAIICKKEK
Sbjct: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEK 180
Query: 181 MVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240
MVEFLLK KAS+HAVDRLR +ALMLAV+YDS GIVNILLKQ+I+VF QDMCGRDAEDYAI
Sbjct: 181 MVEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAI 240
Query: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300
S LTKIQQQILEHKK ILK +K DVGSSDESAVSIFHEL VDSL A DD+ L+VA KQC
Sbjct: 241 SCRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQC 300
Query: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360
VPEKVSEPL G SH KGNRIVNG+GEGPPAKHPSLKPSTE+EDPAVKGAVQ KNVQTLRA
Sbjct: 301 VPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRA 360
Query: 361 EQALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
EQALPVASEEEQQR ERSEKKQPQV EGNNT KSEKIQLSENIC ST SAAA RLTQQRK
Sbjct: 361 EQALPVASEEEQQRRERSEKKQPQVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRK 420
Query: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480
IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNML+KKNREELERKEKQYKKEVEAKQLE
Sbjct: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLE 480
Query: 481 PTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540
PTVQSLEMK KTARNTPN DFHNHEE+K LMDENCILK DIAILRQEICTMKNDNLEKEN
Sbjct: 481 PTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540
Query: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKK 600
KYLKDIKI KETNAALEK IKLNEEMIT+TAF YQQELNDLKAENTRLN+ELLKEKESKK
Sbjct: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKK 600
Query: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFL 660
+LEA+IESYQSRLAAAISKHSE+VKTERNLKLALERTQD+S QV+MSS IS+++D+N FL
Sbjct: 601 KLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFL 660
Query: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKV 720
TEQLS+ QIKFN LKDKFRKTRD+LRKKSLALETVQN+LSQTQQQ +EMKEMYQ+AEAKV
Sbjct: 661 TEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKV 720
Query: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDFVLEE 780
+ STGKWNCVEERIC LQREN WL QQL DVHQKEDHKEIV NIQRGFIES KKD +LEE
Sbjct: 721 SKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEE 780
Query: 781 KSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYFQTSRKKI 823
K+KKLMNE DHLKESLFQYER+K E VVSIKEDKYFQTSRKK+
Sbjct: 781 KNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQTSRKKV 823
>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 1420 bits (3676), Expect = 0.0
Identities = 727/823 (88%), Positives = 768/823 (93%)
Query: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGEL 60
MKLFGF SRRGQT GSIDH+YTGSGYRIR SELQKIH+AAVKGDAAE+ERCLARRSG+L
Sbjct: 1 MKLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDL 60
Query: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120
DALDKQHRTALHLACASGHV+VVTLLVNRKCQID+ DKENRTPLIQAVHCQEEACAVILL
Sbjct: 61 DALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILL 120
Query: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180
EHGANPNLKDIYGNTALHYAVYSESTSLAEKLL HG +IEALDKD+NTPLLFAIICKKEK
Sbjct: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEK 180
Query: 181 MVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240
MVEFLLK KAS+HAVDRLR +ALMLAV+YDS GIVNILLKQ+I+VF QDMCGRDAEDYAI
Sbjct: 181 MVEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAI 240
Query: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300
S LTKIQQQILEHKK ILK +K DVGSSDESAVSIFHEL VDSL A DD+ L+VA KQC
Sbjct: 241 SCRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQC 300
Query: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360
VPEKVSEPL G SH KGNRIVNG+GEGPPAKHPSLKPSTE+EDPAVKGAVQ KNVQTLRA
Sbjct: 301 VPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRA 360
Query: 361 EQALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420
EQALPVASEEEQQR ERSEKKQPQV EGNNT KSEKIQLSENIC ST SAAA RLTQQRK
Sbjct: 361 EQALPVASEEEQQRRERSEKKQPQVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRK 420
Query: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480
IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNML+KKNREELERKEKQYKKEVEAKQLE
Sbjct: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLE 480
Query: 481 PTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540
PTVQSLEMK KTARNTPN DFHNHEE+K LMDENCILK DIAILRQEICTMKNDNLEKEN
Sbjct: 481 PTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540
Query: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKK 600
KYLKDIKI KETNAALEK IKLNEEMIT+TAF YQQELNDLKAENTRLN+ELLKEKESKK
Sbjct: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKK 600
Query: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFL 660
+LEA+IESYQSRLAAAISKHSE+VKTERNLKLALERTQD+S QV+MSS IS+++D+N FL
Sbjct: 601 KLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFL 660
Query: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKV 720
TEQLS+ QIKFN LKDKFRKTRD+LRKKSLALETVQN+LSQTQQQ +EMKEMYQ+AEAKV
Sbjct: 661 TEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKV 720
Query: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDFVLEE 780
+ STGKWNCVEERIC LQREN WL QQL DVHQKEDHKEIV NIQRGFIES KKD +LEE
Sbjct: 721 SKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEE 780
Query: 781 KSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYFQTSRKKI 823
K+KKLMNE DHLKESLFQYER+K E VVSIKEDKYFQTSRKK+
Sbjct: 781 KNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQTSRKKV 823
>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
Length = 917
Score = 470 bits (1210), Expect = e-132
Identities = 312/839 (37%), Positives = 471/839 (56%), Gaps = 68/839 (8%)
Query: 22 YTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELDALDKQHRTALHLACASGHVQ 81
++ GYR+R +L IH+AA+ GD +V + R +L+ DK++RTAL LACA G
Sbjct: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86
Query: 82 VVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141
VV LV RKCQ+++ D ENRT LI+AV CQEE CA ILLEHGANPN++D+YGNTALHYA+
Sbjct: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146
Query: 142 YSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRLRRS 201
+E+ S+A KLL++GA IEA +D +T LL A+ KKE+MV FLLKKK A+D R+
Sbjct: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRT 206
Query: 202 ALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKILKK 261
AL+LA S +V LL+ NIDVF QD+ G AEDYA++ I+ I E+K K+
Sbjct: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKAN--KR 264
Query: 262 EKSDVGSSDESAVSIFHELRVDSLPA--SDDKDLNVATKQCVPEK--VSEPLPGSSHEKG 317
KS S+ E + + E + L S + K+C +K VS + +
Sbjct: 265 RKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNY 324
Query: 318 N----RIVNGQGEGPPAKHPSL-KPSTEVEDPAVKGAVQRKNVQTL--------RAEQAL 364
N +++ P H S K + E + A K + ++ V++ +
Sbjct: 325 NDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSS 384
Query: 365 PVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK---- 420
SE+++ + E +K+ K + + LS++ ++AA GR + +K
Sbjct: 385 EKTSEDDELPYSDDENFMLLIKQSGMECK-DFVSLSKS---KNATAACGRSIEDQKCYCE 440
Query: 421 ---------------IGKTYPQQFPKKLKEEHD-----------RCTLKQENEEKTNVNM 454
+ K + K + EH R L+Q+ EE+
Sbjct: 441 RLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEE 500
Query: 455 LYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDE 513
LY+K+ EEL+ E+QY+ + E KQ + T++SLE++ KT R+ N +FH HE + L E
Sbjct: 501 LYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQE 560
Query: 514 NCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFR 573
N +++ +IA LR EI T+K+ N E ENKY KDI+I+KE N LEK +K NEE +T+T R
Sbjct: 561 NHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITR 620
Query: 574 YQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLA 633
Y +ELN L ENT LN+EL KEK+S RLE ++ESY+ RLAAA+ H + ++R+L+LA
Sbjct: 621 YSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLA 680
Query: 634 LERTQD--VSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLA 691
+ T + +Q + +S I + L++QLS+ + + L+ + R++L++K+L
Sbjct: 681 FQSTVNEWCHLQEDTNSHI-------QILSQQLSKAESTSSGLETELHYEREALKEKTLH 733
Query: 692 LETVQNNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDV 751
+E +Q LS+TQ++ ++++ MYQN + + K VE+ + LQ +N QQ +D
Sbjct: 734 IEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDA 793
Query: 752 HQKEDHKE-IVTNIQRGFIESGKKDFV----LEEKSKKLMNECDHLKESLFQYEREKTE 805
+K D++E + NIQ ++ +K LEE +K LM EC LKE QYE+EK E
Sbjct: 794 RKKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEE 852
>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
sapiens]
Length = 917
Score = 470 bits (1210), Expect = e-132
Identities = 312/839 (37%), Positives = 471/839 (56%), Gaps = 68/839 (8%)
Query: 22 YTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELDALDKQHRTALHLACASGHVQ 81
++ GYR+R +L IH+AA+ GD +V + R +L+ DK++RTAL LACA G
Sbjct: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86
Query: 82 VVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141
VV LV RKCQ+++ D ENRT LI+AV CQEE CA ILLEHGANPN++D+YGNTALHYA+
Sbjct: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146
Query: 142 YSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRLRRS 201
+E+ S+A KLL++GA IEA +D +T LL A+ KKE+MV FLLKKK A+D R+
Sbjct: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRT 206
Query: 202 ALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKILKK 261
AL+LA S +V LL+ NIDVF QD+ G AEDYA++ I+ I E+K K+
Sbjct: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKAN--KR 264
Query: 262 EKSDVGSSDESAVSIFHELRVDSLPA--SDDKDLNVATKQCVPEK--VSEPLPGSSHEKG 317
KS S+ E + + E + L S + K+C +K VS + +
Sbjct: 265 RKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNY 324
Query: 318 N----RIVNGQGEGPPAKHPSL-KPSTEVEDPAVKGAVQRKNVQTL--------RAEQAL 364
N +++ P H S K + E + A K + ++ V++ +
Sbjct: 325 NDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSS 384
Query: 365 PVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK---- 420
SE+++ + E +K+ K + + LS++ ++AA GR + +K
Sbjct: 385 EKTSEDDELPYSDDENFMLLIKQSGMECK-DFVSLSKS---KNATAACGRSIEDQKCYCE 440
Query: 421 ---------------IGKTYPQQFPKKLKEEHD-----------RCTLKQENEEKTNVNM 454
+ K + K + EH R L+Q+ EE+
Sbjct: 441 RLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEE 500
Query: 455 LYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDE 513
LY+K+ EEL+ E+QY+ + E KQ + T++SLE++ KT R+ N +FH HE + L E
Sbjct: 501 LYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQE 560
Query: 514 NCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFR 573
N +++ +IA LR EI T+K+ N E ENKY KDI+I+KE N LEK +K NEE +T+T R
Sbjct: 561 NHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITR 620
Query: 574 YQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLA 633
Y +ELN L ENT LN+EL KEK+S RLE ++ESY+ RLAAA+ H + ++R+L+LA
Sbjct: 621 YSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLA 680
Query: 634 LERTQD--VSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLA 691
+ T + +Q + +S I + L++QLS+ + + L+ + R++L++K+L
Sbjct: 681 FQSTVNEWCHLQEDTNSHI-------QILSQQLSKAESTSSGLETELHYEREALKEKTLH 733
Query: 692 LETVQNNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDV 751
+E +Q LS+TQ++ ++++ MYQN + + K VE+ + LQ +N QQ +D
Sbjct: 734 IEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDA 793
Query: 752 HQKEDHKE-IVTNIQRGFIESGKKDFV----LEEKSKKLMNECDHLKESLFQYEREKTE 805
+K D++E + NIQ ++ +K LEE +K LM EC LKE QYE+EK E
Sbjct: 794 RKKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEE 852
>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
sapiens]
Length = 917
Score = 467 bits (1202), Expect = e-131
Identities = 310/838 (36%), Positives = 469/838 (55%), Gaps = 66/838 (7%)
Query: 22 YTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELDALDKQHRTALHLACASGHVQ 81
++ GYR+R +L IH+AA+ GD +V + R +L+ DK++RTAL LACA G
Sbjct: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86
Query: 82 VVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141
VV LV RKCQ+++ D ENRT LI+AV CQEE CA ILLEHGANPN++D+YGNTALHYA+
Sbjct: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146
Query: 142 YSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRLRRS 201
+E+ S+A KLL++GA IEA +D +T LL A+ KKE+MV FLLKKK A+D R+
Sbjct: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVAFLLKKKPDLTAIDNFGRT 206
Query: 202 ALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKILKK 261
AL+LA S +V LL+ NIDVF QD+ G AEDYA++ I+ I E+K K+
Sbjct: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKAN--KR 264
Query: 262 EKSDVGSSDESAVSIFHELRVDSLPA--SDDKDLNVATKQCVPEK--VSEPLPGSSHEKG 317
KS S+ E + + E + L S + K+C +K VS + +
Sbjct: 265 CKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNY 324
Query: 318 N----RIVNGQGEGPPAKHPSL-KPSTEVEDPAVKGAVQRKNVQT-------LRAEQALP 365
N +++ P H S K + E + A K + ++ V++ L
Sbjct: 325 NDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSS 384
Query: 366 VASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK----- 420
+ E+ + ++ + E + + + LS++ ++AA GR + +K
Sbjct: 385 EKTSEDDELPYSDDENFMLLIEQSGMECKDFVSLSKS---KNATAACGRSIEDQKCYCER 441
Query: 421 --------------IGKTYPQQFPKKLKEEHD-----------RCTLKQENEEKTNVNML 455
+ K + K + EH R L+Q+ EE+ L
Sbjct: 442 LKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEEL 501
Query: 456 YKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDEN 514
Y+K+ EEL+ E+QY+ + E KQ + T++SLE++ KT R+ N +FH HE + L EN
Sbjct: 502 YEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQEN 561
Query: 515 CILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRY 574
+++ +IA LR EI T+K+ N E ENKY KDI+I+KE N LEK +K NEE +T+T RY
Sbjct: 562 HLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEEALTKTITRY 621
Query: 575 QQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLAL 634
+ELN L ENT LN+EL KEK+S RLE ++ESY+ RLAAA+ H + ++R+L+LA
Sbjct: 622 SKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAF 681
Query: 635 ERTQD--VSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLAL 692
+ T + +Q + +S I + L++QLS+ + + L+ + R++L++K+L +
Sbjct: 682 QSTVNEWCHLQEDTNSHI-------QILSQQLSKAESTSSGLETELHYEREALKEKTLHI 734
Query: 693 ETVQNNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVH 752
E +Q LS+TQ++ ++++ MYQN + + K VE+ + LQ +N QQ +D
Sbjct: 735 EHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDAR 794
Query: 753 QKEDHKE-IVTNIQRGFIESGKKDFV----LEEKSKKLMNECDHLKESLFQYEREKTE 805
+K D++E + NIQ ++ +K LEE +K LM EC LKE QYE+EK E
Sbjct: 795 KKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEE 852
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 378 bits (970), Expect = e-104
Identities = 269/791 (34%), Positives = 392/791 (49%), Gaps = 142/791 (17%)
Query: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELD 61
KL FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVE CL RR +LD
Sbjct: 102 KLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLD 161
Query: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121
DK+ RT LHLACA G VQVVTLL++RKCQI++CD+ NRTPL++AVHCQEEACA+ILL+
Sbjct: 162 VRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLK 221
Query: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181
GANPN+KDIYGNTALHYAVY+E TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M
Sbjct: 222 RGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 281
Query: 182 VEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241
VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA
Sbjct: 282 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFC 341
Query: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301
L IQQQILEHK K+LK + LR D N T
Sbjct: 342 CDLRSIQQQILEHKNKMLK-----------------NHLRND----------NQETAAMK 374
Query: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361
PE + + K + + + EG A+H
Sbjct: 375 PENLKK-------RKKRKKLKKRKEGAKAEH----------------------------- 398
Query: 362 QALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKI 421
L VASEE+Q+R ERSE KQPQ + K E G +R I
Sbjct: 399 -NLKVASEEKQERLERSENKQPQDSQSYGKKKDEMF---------------GNFMLKRDI 442
Query: 422 GKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKK----NREELERKEKQYKKEVEAK 477
+ + K QE + T +N ++K N E + +K QY +++
Sbjct: 443 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLN-- 500
Query: 478 QLEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLE 537
++K++ AR + H + + L+A++ L + T N+ E
Sbjct: 501 ---------DLKAENARLNSKLEKEKHNKER--------LEAEVESLHSNLATAINEYNE 543
Query: 538 KENKYLKDIKIV---------KETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRL 588
+ KD+++V ET + + E++TE + + + N LK +
Sbjct: 544 ILER--KDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRET 601
Query: 589 NAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQDVSVQVEMSS 648
L ++ + + ++ D++ Q R+ H E +Q + Q
Sbjct: 602 RDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKE---------SQSIGKQNSSEE 652
Query: 649 AISKVKDENEFLTEQLSET-------QIKFNALKDKFRKTRDSL---RKKSLALE--TVQ 696
I + + EN L QL + +I N +D ++ L R K L E ++
Sbjct: 653 RIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMNEYNYLK 712
Query: 697 NNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERI-----CHLQRENAWLVQQ---L 748
L Q +++ E + + + + ++ + K++ E + CH+ + W ++
Sbjct: 713 EKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHINLDETWTSKKKLFQ 772
Query: 749 DDVHQKEDHKE 759
++ +E H+E
Sbjct: 773 VEIQPEEKHEE 783
Score = 304 bits (779), Expect = 2e-82
Identities = 168/374 (44%), Positives = 257/374 (68%), Gaps = 8/374 (2%)
Query: 442 LKQENEEKTNV---NMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498
L+ +N+E + N+ +K R++L+++++ K E L+ + + + + + N
Sbjct: 363 LRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAE---HNLKVASEEKQERLERSENKQP 419
Query: 499 WDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558
D ++ + K M N +LK DIA+L++E+ +KND+L KE KY+++IK + E NA EK
Sbjct: 420 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEK 479
Query: 559 YIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAIS 618
++LNEEMIT+ +Y Q+LNDLKAEN RLN++L KEK +K+RLEA++ES S LA AI+
Sbjct: 480 SVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAIN 539
Query: 619 KHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKF 678
+++E ++ ++L+L L R DVS M S IS++ D+NE LTEQ+ + ++KFN LK K
Sbjct: 540 EYNEILE-RKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKL 598
Query: 679 RKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQ 738
R+TRD+LR+K+LALE+VQ +L Q Q + +EMK+M+ N EAK + S GK N EERI +
Sbjct: 599 RETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRE 658
Query: 739 RENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDFVLEEKSKKLMNECDHLKESLFQ 798
EN L +QL+D ++ D+KEIV NI R +E+GK+D +LEE++K+LMNE ++LKE L Q
Sbjct: 659 LENLLLERQLEDARKEGDNKEIVINIHRDCLENGKED-LLEERNKELMNEYNYLKEKLLQ 717
Query: 799 YEREKTEVVVSIKE 812
YE+EK E V ++E
Sbjct: 718 YEKEKAEREVIVRE 731
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 378 bits (970), Expect = e-104
Identities = 269/791 (34%), Positives = 392/791 (49%), Gaps = 142/791 (17%)
Query: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELD 61
KL FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVE CL RR +LD
Sbjct: 131 KLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLD 190
Query: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121
DK+ RT LHLACA G VQVVTLL++RKCQI++CD+ NRTPL++AVHCQEEACA+ILL+
Sbjct: 191 VRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLK 250
Query: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181
GANPN+KDIYGNTALHYAVY+E TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M
Sbjct: 251 RGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 310
Query: 182 VEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241
VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA
Sbjct: 311 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFC 370
Query: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301
L IQQQILEHK K+LK + LR D N T
Sbjct: 371 CDLRSIQQQILEHKNKMLK-----------------NHLRND----------NQETAAMK 403
Query: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361
PE + + K + + + EG A+H
Sbjct: 404 PENLKK-------RKKRKKLKKRKEGAKAEH----------------------------- 427
Query: 362 QALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKI 421
L VASEE+Q+R ERSE KQPQ + K E G +R I
Sbjct: 428 -NLKVASEEKQERLERSENKQPQDSQSYGKKKDEMF---------------GNFMLKRDI 471
Query: 422 GKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKK----NREELERKEKQYKKEVEAK 477
+ + K QE + T +N ++K N E + +K QY +++
Sbjct: 472 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLN-- 529
Query: 478 QLEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLE 537
++K++ AR + H + + L+A++ L + T N+ E
Sbjct: 530 ---------DLKAENARLNSKLEKEKHNKER--------LEAEVESLHSNLATAINEYNE 572
Query: 538 KENKYLKDIKIV---------KETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRL 588
+ KD+++V ET + + E++TE + + + N LK +
Sbjct: 573 ILER--KDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRET 630
Query: 589 NAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQDVSVQVEMSS 648
L ++ + + ++ D++ Q R+ H E +Q + Q
Sbjct: 631 RDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKE---------SQSIGKQNSSEE 681
Query: 649 AISKVKDENEFLTEQLSET-------QIKFNALKDKFRKTRDSL---RKKSLALE--TVQ 696
I + + EN L QL + +I N +D ++ L R K L E ++
Sbjct: 682 RIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMNEYNYLK 741
Query: 697 NNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERI-----CHLQRENAWLVQQ---L 748
L Q +++ E + + + + ++ + K++ E + CH+ + W ++
Sbjct: 742 EKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHINLDETWTSKKKLFQ 801
Query: 749 DDVHQKEDHKE 759
++ +E H+E
Sbjct: 802 VEIQPEEKHEE 812
Score = 304 bits (779), Expect = 2e-82
Identities = 168/374 (44%), Positives = 257/374 (68%), Gaps = 8/374 (2%)
Query: 442 LKQENEEKTNV---NMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498
L+ +N+E + N+ +K R++L+++++ K E L+ + + + + + N
Sbjct: 392 LRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAE---HNLKVASEEKQERLERSENKQP 448
Query: 499 WDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558
D ++ + K M N +LK DIA+L++E+ +KND+L KE KY+++IK + E NA EK
Sbjct: 449 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEK 508
Query: 559 YIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAIS 618
++LNEEMIT+ +Y Q+LNDLKAEN RLN++L KEK +K+RLEA++ES S LA AI+
Sbjct: 509 SVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAIN 568
Query: 619 KHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKF 678
+++E ++ ++L+L L R DVS M S IS++ D+NE LTEQ+ + ++KFN LK K
Sbjct: 569 EYNEILE-RKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKL 627
Query: 679 RKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQ 738
R+TRD+LR+K+LALE+VQ +L Q Q + +EMK+M+ N EAK + S GK N EERI +
Sbjct: 628 RETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRE 687
Query: 739 RENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDFVLEEKSKKLMNECDHLKESLFQ 798
EN L +QL+D ++ D+KEIV NI R +E+GK+D +LEE++K+LMNE ++LKE L Q
Sbjct: 688 LENLLLERQLEDARKEGDNKEIVINIHRDCLENGKED-LLEERNKELMNEYNYLKEKLLQ 746
Query: 799 YEREKTEVVVSIKE 812
YE+EK E V ++E
Sbjct: 747 YEKEKAEREVIVRE 760
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 377 bits (967), Expect = e-104
Identities = 268/791 (33%), Positives = 392/791 (49%), Gaps = 142/791 (17%)
Query: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELD 61
KL FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVE CL RR +LD
Sbjct: 131 KLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLD 190
Query: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121
D++ RT LHLACA G VQVVTLL++RKCQI++CD+ NRTPL++AVHCQEEACA+ILL+
Sbjct: 191 VRDRKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLK 250
Query: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181
GANPN+KDIYGNTALHYAVY+E TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M
Sbjct: 251 RGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 310
Query: 182 VEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241
VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA
Sbjct: 311 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFC 370
Query: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301
L IQQQILEHK K+LK + LR D N T
Sbjct: 371 CDLRSIQQQILEHKNKMLK-----------------NHLRND----------NQETAAMK 403
Query: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361
PE + + K + + + EG A+H
Sbjct: 404 PENLKK-------RKKRKKLKKRKEGAKAEH----------------------------- 427
Query: 362 QALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKI 421
L VASEE+Q+R ERSE KQPQ + K E G +R I
Sbjct: 428 -NLKVASEEKQERLERSENKQPQDSQSYGKKKDEMF---------------GNFMLKRDI 471
Query: 422 GKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKK----NREELERKEKQYKKEVEAK 477
+ + K QE + T +N ++K N E + +K QY +++
Sbjct: 472 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLN-- 529
Query: 478 QLEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLE 537
++K++ AR + H + + L+A++ L + T N+ E
Sbjct: 530 ---------DLKAENARLNSKLEKEKHNKER--------LEAEVESLHSNLATAINEYNE 572
Query: 538 KENKYLKDIKIV---------KETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRL 588
+ KD+++V ET + + E++TE + + + N LK +
Sbjct: 573 ILER--KDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRET 630
Query: 589 NAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQDVSVQVEMSS 648
L ++ + + ++ D++ Q R+ H E +Q + Q
Sbjct: 631 RDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKE---------SQSIGKQNSSEE 681
Query: 649 AISKVKDENEFLTEQLSET-------QIKFNALKDKFRKTRDSL---RKKSLALE--TVQ 696
I + + EN L QL + +I N +D ++ L R K L E ++
Sbjct: 682 RIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMNEYNYLK 741
Query: 697 NNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERI-----CHLQRENAWLVQQ---L 748
L Q +++ E + + + + ++ + K++ E + CH+ + W ++
Sbjct: 742 EKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHINLDETWTSKKKLFQ 801
Query: 749 DDVHQKEDHKE 759
++ +E H+E
Sbjct: 802 VEIQPEEKHEE 812
Score = 304 bits (779), Expect = 2e-82
Identities = 168/374 (44%), Positives = 257/374 (68%), Gaps = 8/374 (2%)
Query: 442 LKQENEEKTNV---NMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498
L+ +N+E + N+ +K R++L+++++ K E L+ + + + + + N
Sbjct: 392 LRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAE---HNLKVASEEKQERLERSENKQP 448
Query: 499 WDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558
D ++ + K M N +LK DIA+L++E+ +KND+L KE KY+++IK + E NA EK
Sbjct: 449 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEK 508
Query: 559 YIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAIS 618
++LNEEMIT+ +Y Q+LNDLKAEN RLN++L KEK +K+RLEA++ES S LA AI+
Sbjct: 509 SVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAIN 568
Query: 619 KHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKF 678
+++E ++ ++L+L L R DVS M S IS++ D+NE LTEQ+ + ++KFN LK K
Sbjct: 569 EYNEILE-RKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKL 627
Query: 679 RKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQ 738
R+TRD+LR+K+LALE+VQ +L Q Q + +EMK+M+ N EAK + S GK N EERI +
Sbjct: 628 RETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRE 687
Query: 739 RENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDFVLEEKSKKLMNECDHLKESLFQ 798
EN L +QL+D ++ D+KEIV NI R +E+GK+D +LEE++K+LMNE ++LKE L Q
Sbjct: 688 LENLLLERQLEDARKEGDNKEIVINIHRDCLENGKED-LLEERNKELMNEYNYLKEKLLQ 746
Query: 799 YEREKTEVVVSIKE 812
YE+EK E V ++E
Sbjct: 747 YEKEKAEREVIVRE 760
>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]
Length = 561
Score = 374 bits (959), Expect = e-103
Identities = 238/529 (44%), Positives = 321/529 (60%), Gaps = 46/529 (8%)
Query: 265 DVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGNRIVNGQ 324
DVG SDESAVSI HEL VDSLP DD+DL+VATKQCVPEKVSEPL G SHEKGNRIVNG+
Sbjct: 54 DVGISDESAVSILHELCVDSLPTLDDEDLSVATKQCVPEKVSEPLRGPSHEKGNRIVNGK 113
Query: 325 GEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQQRHERSEKKQPQ 384
G+GPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQ LPVA EEEQ+R ERSEKKQ Q
Sbjct: 114 GKGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQTLPVALEEEQERCERSEKKQSQ 173
Query: 385 VKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQ 444
VKEGNNTNKSEKIQLSEN+C STSSAAA RLT+QRK+GKTYPQQFPKKLK+EHD
Sbjct: 174 VKEGNNTNKSEKIQLSENVCHSTSSAAADRLTKQRKVGKTYPQQFPKKLKKEHD------ 227
Query: 445 ENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPNW--DFH 502
REELERKEKQYKKEVEAKQLEPTVQSL+MK KT RNTPN
Sbjct: 228 ---------------REELERKEKQYKKEVEAKQLEPTVQSLDMKLKTTRNTPNQINQSL 272
Query: 503 NHEEMKGLMDENCILKADIAILRQEICTMKN--DNLE-KENKYLKDIKIVKETNAALEKY 559
+ + K + N D++ +Q+I MK +N E K N V+E L+
Sbjct: 273 RYSQKKVIGFRNS--PNDLSQTQQQIKEMKEMYENAEAKVNNSTGKWSCVEERICQLQHE 330
Query: 560 IKLNEEMITETAFR--YQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAI 617
E+ + + + +++ + +++ + L +E K+L + + + L
Sbjct: 331 NPCIEQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLMLEEKNKKLMNECDHLKESLFQYE 390
Query: 618 SKHSESVKTERNLKL----ALERTQDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFN- 672
+ +E V R L+ +L++ + +E S DE + ++L + + +F+
Sbjct: 391 REKAERVVVVRQLQQEAADSLKKLTMLESPLEGISHYHINLDETQVPKKKLFQVESQFDD 450
Query: 673 ------ALKDK---FRKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKVNNS 723
A+ K K +++ L+++ VQ + ++ + ++E N + + NS
Sbjct: 451 FMAEKEAVSSKCVNLAKEIQVFQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENS 510
Query: 724 TGKWNCVEERICHLQRENAWLVQQLDDVHQKE--DHKEIVTNIQRGFIE 770
+ + ++E L V++L+++H +E +HK+ + + + I+
Sbjct: 511 MVELSKLQEYKSELDERAMQAVEKLEEIHLQEQAEHKKQLEQLNKDIIQ 559
Score = 207 bits (527), Expect = 3e-53
Identities = 125/261 (47%), Positives = 158/261 (60%), Gaps = 15/261 (5%)
Query: 562 LNEEMITETAFRYQQELNDLKAENTRLNAELLKE-----KESKKRLEADI-ESYQSRLAA 615
L E A +QE + E + +KE K K +L ++ S S A
Sbjct: 147 LRAEQTLPVALEEEQE----RCERSEKKQSQVKEGNNTNKSEKIQLSENVCHSTSSAAAD 202
Query: 616 AISKHSESVKT-ERNLKLALERTQDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNAL 674
++K + KT + L++ D ++E K + E + L + +K
Sbjct: 203 RLTKQRKVGKTYPQQFPKKLKKEHDRE-ELERKEKQYKKEVEAKQLEPTVQSLDMKLKTT 261
Query: 675 KDKFRKTRDSLR---KKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVE 731
++ + SLR KK + N+LSQTQQQ +EMKEMY+NAEAKVNNSTGKW+CVE
Sbjct: 262 RNTPNQINQSLRYSQKKVIGFRNSPNDLSQTQQQIKEMKEMYENAEAKVNNSTGKWSCVE 321
Query: 732 ERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDFVLEEKSKKLMNECDH 791
ERIC LQ EN + QQLDDVHQKEDHKEIVTNIQRGFIESGKKD +LEEK+KKLMNECDH
Sbjct: 322 ERICQLQHENPCIEQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLMLEEKNKKLMNECDH 381
Query: 792 LKESLFQYEREKTEVVVSIKE 812
LKESLFQYEREK E VV +++
Sbjct: 382 LKESLFQYEREKAERVVVVRQ 402
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 368 bits (945), Expect = e-101
Identities = 291/904 (32%), Positives = 435/904 (48%), Gaps = 120/904 (13%)
Query: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELD 61
KLF FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVERCL RR +LD
Sbjct: 110 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 169
Query: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121
A D++ RT LHLACA G VQVVTLL++R+CQID+CD+ NRTPL++AVH QEEACA++LLE
Sbjct: 170 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 229
Query: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181
GANPN++DIYGNTALHYAVY++ TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M
Sbjct: 230 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 289
Query: 182 VEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241
VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA+
Sbjct: 290 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 349
Query: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301
L I+QQILEHK K+LK + LR D+ + K N+ K+
Sbjct: 350 SDLRSIRQQILEHKNKMLK-----------------NHLRNDNQETAAMKPANL-KKRKE 391
Query: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361
K L +S EK R+ + + P K +D + +K++ L+ E
Sbjct: 392 RAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKK----KDAMYGNFMLKKDIAMLKEE 447
Query: 362 QALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKI 421
A + + R E+ ++ + N N + ++L+E + T R +QQ
Sbjct: 448 L---YAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKT----VARYSQQLND 500
Query: 422 GKTYPQQFPKKL-KEEHDRCTLKQENE--------------------------------- 447
K + +L KE+H++ L+ E E
Sbjct: 501 LKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDVS 560
Query: 448 --EK--TNVNMLYKKNREELERKEKQYKKEVEAK-QLEPTVQSLEMKSKTARNTPNWDF- 501
EK +N++ L KN E+ K K K +L T +L K+ A + D
Sbjct: 561 RHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKT-LALGSVQLDLR 619
Query: 502 ---HNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYL-KDIKIVKETNAALE 557
H +EMK M N K +I +Q + E EN L + ++ ++ E
Sbjct: 620 QAQHRIKEMK-QMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKE 678
Query: 558 KYIKLNEEMITETAFRYQQELN-DLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAA 616
I ++ + + +E N +L E L +LL+ ++ K E + +Q L
Sbjct: 679 IVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELV-- 736
Query: 617 ISKHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKD 676
+ +KT + LE T + + + K + E E+ E K L
Sbjct: 737 -----DHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELIS 791
Query: 677 KFRKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAE------------------- 717
T D +RKK+ LE + + T M + N +
Sbjct: 792 LLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFK 851
Query: 718 ---AKVNNSTGKWNCVEERICHLQRENAWLVQQL---------------DDVHQKEDHKE 759
K N+ + V +L ++N L Q+L D +E+
Sbjct: 852 KLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLN 911
Query: 760 IVTNIQRGFIESGKKDFVLEEKSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYFQTS 819
+ T++++ +E GK E ++ + E + L+E Q + E + + + +D
Sbjct: 912 LKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLK 971
Query: 820 RKKI 823
+K++
Sbjct: 972 KKEL 975
Score = 32.3 bits (72), Expect = 1.8
Identities = 43/203 (21%), Positives = 85/203 (41%), Gaps = 44/203 (21%)
Query: 431 KKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERK--------EKQYKKEVEAKQLEPT 482
KKLK++ + ++E VN+ K+ E L ++ EK K E + K LE
Sbjct: 851 KKLKQKFNDLVAEKEAVSSECVNLA--KDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEE 908
Query: 483 VQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKY 542
V +L KT + +E K +DE + QEI ++ +L+K+ +Y
Sbjct: 909 VLNL----KTHMEKDMVELGKLQEYKSELDERAV---------QEIEKLEEIHLQKQAEY 955
Query: 543 LKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRL 602
K ++ + + N A K +L L D++ + +++ K + + +
Sbjct: 956 EKQLEQLNKDNTASLKKKELT--------------LKDVECKFSKM-------KTAYEEV 994
Query: 603 EADIESYQSRLAAAISKHSESVK 625
++E ++ A A+ ++ K
Sbjct: 995 TTELEEFKEAFAGAVKANNSMSK 1017
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 368 bits (945), Expect = e-101
Identities = 291/904 (32%), Positives = 435/904 (48%), Gaps = 120/904 (13%)
Query: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELD 61
KLF FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVERCL RR +LD
Sbjct: 3 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 62
Query: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121
A D++ RT LHLACA G VQVVTLL++R+CQID+CD+ NRTPL++AVH QEEACA++LLE
Sbjct: 63 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 122
Query: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181
GANPN++DIYGNTALHYAVY++ TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M
Sbjct: 123 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 182
Query: 182 VEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241
VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA+
Sbjct: 183 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 242
Query: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301
L I+QQILEHK K+LK + LR D+ + K N+ K+
Sbjct: 243 SDLRSIRQQILEHKNKMLK-----------------NHLRNDNQETAAMKPANL-KKRKE 284
Query: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361
K L +S EK R+ + + P K +D + +K++ L+ E
Sbjct: 285 RAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKK----KDAMYGNFMLKKDIAMLKEE 340
Query: 362 QALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKI 421
A + + R E+ ++ + N N + ++L+E + T R +QQ
Sbjct: 341 L---YAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKT----VARYSQQLND 393
Query: 422 GKTYPQQFPKKL-KEEHDRCTLKQENE--------------------------------- 447
K + +L KE+H++ L+ E E
Sbjct: 394 LKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDVS 453
Query: 448 --EK--TNVNMLYKKNREELERKEKQYKKEVEAK-QLEPTVQSLEMKSKTARNTPNWDF- 501
EK +N++ L KN E+ K K K +L T +L K+ A + D
Sbjct: 454 RHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKT-LALGSVQLDLR 512
Query: 502 ---HNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYL-KDIKIVKETNAALE 557
H +EMK M N K +I +Q + E EN L + ++ ++ E
Sbjct: 513 QAQHRIKEMK-QMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKE 571
Query: 558 KYIKLNEEMITETAFRYQQELN-DLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAA 616
I ++ + + +E N +L E L +LL+ ++ K E + +Q L
Sbjct: 572 IVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELV-- 629
Query: 617 ISKHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKD 676
+ +KT + LE T + + + K + E E+ E K L
Sbjct: 630 -----DHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELIS 684
Query: 677 KFRKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAE------------------- 717
T D +RKK+ LE + + T M + N +
Sbjct: 685 LLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFK 744
Query: 718 ---AKVNNSTGKWNCVEERICHLQRENAWLVQQL---------------DDVHQKEDHKE 759
K N+ + V +L ++N L Q+L D +E+
Sbjct: 745 KLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLN 804
Query: 760 IVTNIQRGFIESGKKDFVLEEKSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYFQTS 819
+ T++++ +E GK E ++ + E + L+E Q + E + + + +D
Sbjct: 805 LKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLK 864
Query: 820 RKKI 823
+K++
Sbjct: 865 KKEL 868
Score = 32.3 bits (72), Expect = 1.8
Identities = 43/203 (21%), Positives = 85/203 (41%), Gaps = 44/203 (21%)
Query: 431 KKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERK--------EKQYKKEVEAKQLEPT 482
KKLK++ + ++E VN+ K+ E L ++ EK K E + K LE
Sbjct: 744 KKLKQKFNDLVAEKEAVSSECVNLA--KDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEE 801
Query: 483 VQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKY 542
V +L KT + +E K +DE + QEI ++ +L+K+ +Y
Sbjct: 802 VLNL----KTHMEKDMVELGKLQEYKSELDERAV---------QEIEKLEEIHLQKQAEY 848
Query: 543 LKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRL 602
K ++ + + N A K +L L D++ + +++ K + + +
Sbjct: 849 EKQLEQLNKDNTASLKKKELT--------------LKDVECKFSKM-------KTAYEEV 887
Query: 603 EADIESYQSRLAAAISKHSESVK 625
++E ++ A A+ ++ K
Sbjct: 888 TTELEEFKEAFAGAVKANNSMSK 910
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 368 bits (945), Expect = e-101
Identities = 291/904 (32%), Positives = 435/904 (48%), Gaps = 120/904 (13%)
Query: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELD 61
KLF FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVERCL RR +LD
Sbjct: 110 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 169
Query: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121
A D++ RT LHLACA G VQVVTLL++R+CQID+CD+ NRTPL++AVH QEEACA++LLE
Sbjct: 170 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 229
Query: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181
GANPN++DIYGNTALHYAVY++ TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M
Sbjct: 230 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 289
Query: 182 VEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241
VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA+
Sbjct: 290 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 349
Query: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301
L I+QQILEHK K+LK + LR D+ + K N+ K+
Sbjct: 350 SDLRSIRQQILEHKNKMLK-----------------NHLRNDNQETAAMKPANL-KKRKE 391
Query: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361
K L +S EK R+ + + P K +D + +K++ L+ E
Sbjct: 392 RAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKK----KDAMYGNFMLKKDIAMLKEE 447
Query: 362 QALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKI 421
A + + R E+ ++ + N N + ++L+E + T R +QQ
Sbjct: 448 L---YAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKT----VARYSQQLND 500
Query: 422 GKTYPQQFPKKL-KEEHDRCTLKQENE--------------------------------- 447
K + +L KE+H++ L+ E E
Sbjct: 501 LKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDVS 560
Query: 448 --EK--TNVNMLYKKNREELERKEKQYKKEVEAK-QLEPTVQSLEMKSKTARNTPNWDF- 501
EK +N++ L KN E+ K K K +L T +L K+ A + D
Sbjct: 561 RHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKT-LALGSVQLDLR 619
Query: 502 ---HNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYL-KDIKIVKETNAALE 557
H +EMK M N K +I +Q + E EN L + ++ ++ E
Sbjct: 620 QAQHRIKEMK-QMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKE 678
Query: 558 KYIKLNEEMITETAFRYQQELN-DLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAA 616
I ++ + + +E N +L E L +LL+ ++ K E + +Q L
Sbjct: 679 IVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELV-- 736
Query: 617 ISKHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKD 676
+ +KT + LE T + + + K + E E+ E K L
Sbjct: 737 -----DHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELIS 791
Query: 677 KFRKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAE------------------- 717
T D +RKK+ LE + + T M + N +
Sbjct: 792 LLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFK 851
Query: 718 ---AKVNNSTGKWNCVEERICHLQRENAWLVQQL---------------DDVHQKEDHKE 759
K N+ + V +L ++N L Q+L D +E+
Sbjct: 852 KLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLN 911
Query: 760 IVTNIQRGFIESGKKDFVLEEKSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYFQTS 819
+ T++++ +E GK E ++ + E + L+E Q + E + + + +D
Sbjct: 912 LKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLK 971
Query: 820 RKKI 823
+K++
Sbjct: 972 KKEL 975
Score = 32.3 bits (72), Expect = 1.8
Identities = 43/203 (21%), Positives = 85/203 (41%), Gaps = 44/203 (21%)
Query: 431 KKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERK--------EKQYKKEVEAKQLEPT 482
KKLK++ + ++E VN+ K+ E L ++ EK K E + K LE
Sbjct: 851 KKLKQKFNDLVAEKEAVSSECVNLA--KDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEE 908
Query: 483 VQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKY 542
V +L KT + +E K +DE + QEI ++ +L+K+ +Y
Sbjct: 909 VLNL----KTHMEKDMVELGKLQEYKSELDERAV---------QEIEKLEEIHLQKQAEY 955
Query: 543 LKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRL 602
K ++ + + N A K +L L D++ + +++ K + + +
Sbjct: 956 EKQLEQLNKDNTASLKKKELT--------------LKDVECKFSKM-------KTAYEEV 994
Query: 603 EADIESYQSRLAAAISKHSESVK 625
++E ++ A A+ ++ K
Sbjct: 995 TTELEEFKEAFAGAVKANNSMSK 1017
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 320 bits (821), Expect = 3e-87
Identities = 192/444 (43%), Positives = 273/444 (61%), Gaps = 62/444 (13%)
Query: 431 KKLKEEHDRCTLK----QENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQ-LEPTVQS 485
+K++ E + C+L+ QE E++ N + LY+K RE+L RKE+QY+KEVE KQ LE ++Q+
Sbjct: 780 QKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQT 839
Query: 486 LEMKSKTARNTPNW---------------------------------------------- 499
LEM+ +T ++ N
Sbjct: 840 LEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSE 899
Query: 500 DFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKY 559
+ H+HEE K L +N +L+ +IA+LR EI T+KN N EKE K +D+KIVKE N L+K
Sbjct: 900 NSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKT 959
Query: 560 IKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISK 619
IK NEE +T+T +Y L+ L AEN LN++L EK+SK+RLEA++ESY SRLAAAI
Sbjct: 960 IKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD 1019
Query: 620 HSESVKTERNLKLALERTQD--VSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDK 677
+S ++R L+LA +R +D +Q +M+ +S +KD NE L++QL +T+ K N+L+ +
Sbjct: 1020 RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIE 1079
Query: 678 FRKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHL 737
F TRD+LR+K+L LE VQ +LSQTQ Q +EM++ YQN + KVN GK VEER+ L
Sbjct: 1080 FHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQL 1139
Query: 738 QRENAWLVQQLDDVHQKEDHKE-IVTNIQRGF--------IESGKKDFVLEEKSKKLMNE 788
Q EN L QQLDD H K D+KE V NIQ F ES K+ +LEE++K+L++E
Sbjct: 1140 QSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISE 1199
Query: 789 CDHLKESLFQYEREKTEVVVSIKE 812
C+HLKE +QYE EK E V +++
Sbjct: 1200 CNHLKERQYQYENEKAEREVVVRQ 1223
Score = 231 bits (588), Expect = 3e-60
Identities = 131/308 (42%), Positives = 183/308 (59%), Gaps = 44/308 (14%)
Query: 11 GQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELDALDKQHRTA 70
G+ +G+ Y+ GY +RD +L KIH+AA G+ A+V++ L R L+ DK +RTA
Sbjct: 28 GEPGEGA----YSQPGYHVRDRDLGKIHKAASAGNVAKVQQILLLRKNGLNDRDKMNRTA 83
Query: 71 LHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKD 130
LHLACA+GH +VVTLLV+RKCQ++VCD ENRT L++AV CQEE CA ILLEHGA+PNL D
Sbjct: 84 LHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATILLEHGADPNLAD 143
Query: 131 IYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKA 190
++GNTALHYAVY+E S+A KLL + A+IEA +KD+ TPLL A+ KK++MVEFL+KKKA
Sbjct: 144 VHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKA 203
Query: 191 SSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQ 250
+ +AVD+L S +++ Y ++ I H ++
Sbjct: 204 NVNAVDKLESSHQLISEY---------------------------KEERIPKHSSQNSNS 236
Query: 251 ILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLP 310
+ E + L + G DS P SDD+DLN TK +++ +
Sbjct: 237 VDESSEDSLSRLSGKPGVD-------------DSWPTSDDEDLNFDTKNVPKPSLAKLMT 283
Query: 311 GSSHEKGN 318
S + N
Sbjct: 284 ASQQSRKN 291
Score = 103 bits (256), Expect = 8e-22
Identities = 148/643 (23%), Positives = 276/643 (42%), Gaps = 114/643 (17%)
Query: 262 EKSDVGS--SDESAVSIFHELRVDSLP-ASDDKDLNVATKQCVPE-KVSEPLPGSSHEKG 317
++ D+ S ES F + VD L A+D K+ N+ +Q + + GS + K
Sbjct: 412 QEEDIESPWDSESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKM 471
Query: 318 NRIVNGQGEGPPAKHPS-------LKPSTEVEDPAVKGAVQRKNVQTLRA-EQALPVASE 369
++ + + G P H LKP+ E++D A K+VQT +A E L VASE
Sbjct: 472 AKLEDTRNVGMPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASE 531
Query: 370 EEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAA-----GRLTQQRKIGKT 424
EEQ+R E SE QPQV+E +++ ++++S NI D + A L Q+RK G+T
Sbjct: 532 EEQER-EGSENNQPQVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGET 590
Query: 425 YPQQFPKKLKEEHD-----------RCTLKQENEEKTNVNM-LYKK-------------- 458
QQFP+K +E+ + T K++ K +VN ++ K
Sbjct: 591 DHQQFPRKENKEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDD 650
Query: 459 -NREELERKEKQYKKEV--EAKQLEPTVQSLE------MKSKTAR---NTPNWDFHNHE- 505
+ E++ E + K+ E +++ +QS++ S+TA P+ + N
Sbjct: 651 SSLSEIDEDEGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFML 710
Query: 506 --EMKGL--MDENCILK-ADIAILRQEICTMKNDNLE-----------KENKYLKDIKIV 549
E G+ D +LK D A+ + + +K ++ E K N +++
Sbjct: 711 LIEQLGMECKDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSET 770
Query: 550 KETNAALEKYIKLNEEMITETAFRYQQE----------LNDLKAENTRLNAELLKEKESK 599
KE + LE E + F QE ++ + R + KE E K
Sbjct: 771 KEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVK 830
Query: 600 KRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQD------------VSVQVEMS 647
++LE +++ + L S ++ V+ + + L R Q+ +S Q E+
Sbjct: 831 QQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIE 890
Query: 648 SAISKVKDENEFLTEQLSETQIKFNALKDKFRKTR---DSLRKKSLALE-TVQNNLSQTQ 703
A K+ EN E+ + K + L+++ R D+++ ++ E +L +
Sbjct: 891 MAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVK 950
Query: 704 QQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKED------- 756
++ +++++ + E + + ++N R+ L ENA L +L++ Q ++
Sbjct: 951 EKNEDLQKTIKQNEETLTQTISQYN---GRLSVLTAENAMLNSKLENEKQSKERLEAEVE 1007
Query: 757 --HKEIVTNI-QRGFIESGKKDFVLEEKSKKLMNECDHLKESL 796
H + I R E+ K++ LE ++ +EC L++ +
Sbjct: 1008 SYHSRLAAAIHDRDQSETSKRE--LELAFQRARDECSRLQDKM 1048
Score = 43.9 bits (102), Expect = 6e-04
Identities = 93/509 (18%), Positives = 203/509 (39%), Gaps = 79/509 (15%)
Query: 376 ERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKE 435
++SE + +++ + E +L + + S+ +++ KT + +++
Sbjct: 1021 DQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEF 1080
Query: 436 EHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEV--------EAKQLEPTVQSLE 487
H R L+++ V + + +++ E++Y+ E + + +E + L+
Sbjct: 1081 HHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQ 1140
Query: 488 MKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYL---- 543
++ R + D HN + K K I I Q ++ E E + L
Sbjct: 1141 SENMLLRQQLD-DAHNKADNKE--------KTVINIQDQFHAIVQKLQAESEKQSLLLEE 1191
Query: 544 KDIKIVKETNAALEK-YIKLNEEMITETAFRY-QQELNDLKAENTRLNAEL-------LK 594
++ +++ E N E+ Y NE+ E R QQEL D + + A L +
Sbjct: 1192 RNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRIN 1251
Query: 595 EKESKKRLEADIESYQSRLAAAISKHSESVKTERNL---KLALERTQDVSVQVEMSSAIS 651
++ + L+ + +++L A +H+E+V+ + K LE+ + ++V + +
Sbjct: 1252 LEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEK-DNAKLKVTVKKQMD 1310
Query: 652 KVKDE-----NEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNNLSQTQQQT 706
K+++ N L+E E K LK D KK++ LE + T
Sbjct: 1311 KIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMT 1370
Query: 707 QEMKEMYQNAE----------------------AKVNNSTGKWNCVEERICHLQRENAWL 744
++ Y+N E K+++ T + + HL +N L
Sbjct: 1371 RKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQIL 1430
Query: 745 VQQLDDV------------HQKEDHKEIV---TNIQRGFIESGK-KDFVLEEKSKKLMNE 788
++L + ++K+ +E++ ++I+R +E G+ K + E + +
Sbjct: 1431 QEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEI 1490
Query: 789 CDHLKE-SLF-QYEREKTEVVVSIKEDKY 815
+ LKE +LF Q + E + +E+ +
Sbjct: 1491 AEKLKEVNLFLQAQAASQENLEQFRENNF 1519
>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
Length = 1341
Score = 281 bits (719), Expect = 2e-75
Identities = 185/525 (35%), Positives = 288/525 (54%), Gaps = 51/525 (9%)
Query: 328 PPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQQRHE---------RS 378
PP K + +P+ E++ A++ KN QTLRA+Q P SE +Q++ E R
Sbjct: 817 PPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADQMFP--SESKQKKVEENSWDSESLRE 874
Query: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAA----------------------AGRLT 416
Q V T++ E ++S + DSTS + G++
Sbjct: 875 TVSQKDVCVPKATHQKEMDKISGKLEDSTSLSKILDTVHSCERARELQKDHCEQRTGKME 934
Query: 417 QQRKI----------GKTYPQQFP-KKLKEEHDRC----TLKQENEEKTNVNMLYKKNRE 461
Q +K K Q +K+K E + C TL QE E++ N ++L +K RE
Sbjct: 935 QMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEEKRRNADILNEKIRE 994
Query: 462 ELERKEKQYKKEVEAKQ-LEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKAD 520
EL R E+Q++KE+E KQ LE ++ +++ K+ + N H HE L+ ENC+LK +
Sbjct: 995 ELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTHENENYLLHENCMLKKE 1054
Query: 521 IAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELND 580
IA+L+ EI T+K+ EKENKY +DIKI+KE NA L+ +KL EE +T+ A +Y +L
Sbjct: 1055 IAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQLKV 1114
Query: 581 LKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQDV 640
L AENT L ++L KEK+ K+ LEA+IES+ RLA+A+ H + V + ++ + A D
Sbjct: 1115 LIAENTMLTSKL-KEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDA 1173
Query: 641 SVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNNLS 700
+Q +M+ +S NE L + LSE Q K +LK D+LR+ +L E Q +
Sbjct: 1174 CLQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQR 1233
Query: 701 QTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEI 760
+TQ Q +E + MYQN + VN T + +++++ LQ +N WL QQL H+K D+K
Sbjct: 1234 ETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSK 1293
Query: 761 VTNIQRGFIESGKKDFVLEEKSKKLMNECDHLKESLFQYEREKTE 805
+T I F+E + +L+EK++++ N +HLK ++QYE+EK E
Sbjct: 1294 IT-IDIHFLERKMQHHLLKEKNEEIFNYNNHLKNRIYQYEKEKAE 1337
Score = 224 bits (572), Expect = 2e-58
Identities = 171/500 (34%), Positives = 257/500 (51%), Gaps = 67/500 (13%)
Query: 55 RRSGELDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEA 114
+++ L+ D Q RTALH AC +GH +VVT LV+RKCQ+DV D E+RTPL++A+ C +EA
Sbjct: 5 KKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEA 64
Query: 115 CAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAI 174
CA IL++ GA+ NL D+YGNTALHYAVYSE S+ KLLSHGA IE +K + TPLL +I
Sbjct: 65 CANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSI 124
Query: 175 ICKKEKMVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRD 234
+ E++VEFLL K A+++AV++ + +ALMLAV + S IV +LL+QN+DVFA D+CG
Sbjct: 125 TKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVT 184
Query: 235 AEDYAISHHLTKIQQQILEHKKKILKK------EKSDVGSSDE----------SAVSIFH 278
AE YA++ I +QI+E+ +K+ K E + G+ DE +A S+
Sbjct: 185 AEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVE 244
Query: 279 ELRVDSLPASD-DKDLNVATKQCVPEKVSEPLPGSSHE-------KGNRIVNGQGEGP-- 328
+ ++ P + D + + P++ + + G+S + + E P
Sbjct: 245 KTPDEAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEETPRE 304
Query: 329 ---PAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASE------EEQQRHERSE 379
PAK S K + + K A ++K SE + + R E
Sbjct: 305 ITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWE 364
Query: 380 KKQPQVKEG-------NNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKK 432
KK+ VK G N T EK + C + S+ QR FP +
Sbjct: 365 KKETPVKTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQR---------FPSE 415
Query: 433 LKEEHDR---CTLKQENEEKTNVNM-----LYKK----NR--EELERKEKQYKKEVEAKQ 478
K+E D C + E + + +Y+K NR EE +K +K +E +
Sbjct: 416 SKQEEDEEYSCDSRSLFESSAKIQVCIPESIYQKVMEINREVEEPPKKPSAFKPAIEMQN 475
Query: 479 LEPTVQSLEMKS-KTARNTP 497
P ++ E+K+ +T R P
Sbjct: 476 SVPN-KAFELKNEQTLRADP 494
Score = 60.1 bits (144), Expect = 8e-09
Identities = 122/621 (19%), Positives = 244/621 (39%), Gaps = 74/621 (11%)
Query: 250 QILEHKKKILKKEKSDV---GSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPE--- 303
++ +K K+L+K +S + + + S + ++ R S ++ + + + E
Sbjct: 377 RVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEEDEEYSCDSRSLFESSA 436
Query: 304 KVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQA 363
K+ +P S ++K I N + E PP K + KP+ E+++ A + KN QTLRA+
Sbjct: 437 KIQVCIPESIYQKVMEI-NREVEEPPKKPSAFKPAIEMQNSVPNKAFELKNEQTLRADPM 495
Query: 364 LPVASEEEQQRHERSEKK-------QPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLT 416
P S+++ + + Q V T++ E +++ + +S + + T
Sbjct: 496 FPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPNKDGLLKAT 555
Query: 417 QQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNV-------------NMLYKKNREEL 463
K+ P K E D T K E K + L KN + L
Sbjct: 556 CGMKV------SIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALELKNEQTL 609
Query: 464 --------ERKEKQYKKEV-EAKQLEPTVQSLEMKSKTARNTPNWDFHNHE-----EMKG 509
E K+K Y++ + + L TV ++ A + D N + G
Sbjct: 610 RADEILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDG 669
Query: 510 LMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITE 569
L+ NC +K I E+ M+ E K ++ + K ++L E
Sbjct: 670 LLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLR 729
Query: 570 TAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERN 629
E E + ++E L E S+K + ++Q + K ES +
Sbjct: 730 ADEILPSESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGF 789
Query: 630 LKLALERTQDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKS 689
LK ++V + + ++ D F E + A+ + + S+ K+
Sbjct: 790 LKAPCR------MKVSIPTKALELMDMQTFKAEPPEKPSAFEPAI-----EMQKSVPNKA 838
Query: 690 LALETVQ----NNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVE--------ERICHL 737
L L+ Q + + ++ + ++++E ++E+ + K CV ++I
Sbjct: 839 LELKNEQTLRADQMFPSESKQKKVEENSWDSESLRETVSQKDVCVPKATHQKEMDKISGK 898
Query: 738 QRENAWLVQQLDDVHQKEDHKEIVTN---IQRGFIESGKKDF-VLEEKSKKLMNECDHLK 793
++ L + LD VH E +E+ + + G +E KK F VL++K + L+
Sbjct: 899 LEDSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLE 958
Query: 794 ESLFQYEREKTEVVVSIKEDK 814
++E+E V +++ +++
Sbjct: 959 NQKVKWEQELCSVRLTLNQEE 979
>gi|153791352 prostate, ovary, testis expressed protein on
chromosome 2 [Homo sapiens]
Length = 1075
Score = 271 bits (693), Expect = 2e-72
Identities = 205/606 (33%), Positives = 311/606 (51%), Gaps = 92/606 (15%)
Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELDALDKQHRTALHLACASG 78
D + Y +R +L K+HRAA G + + R +++ DKQ RTALHLA A+G
Sbjct: 125 DSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKQDKQKRTALHLASANG 184
Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138
+ +VV LL++R+CQ++V D + RT LI+AV CQE+ CA++LLEHG +PN+ D YGNT LH
Sbjct: 185 NSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRL 198
YA+Y+E +A+ LL +GA IE+ +K TPLL + +K+++V+FL+KKKA+ +A+DR
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258
R+AL+LAV S IV++LL+QNIDV +QD+ G+ A +YA+S H I Q + ++K+K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPE-------KVSEPLPG 311
+ K S+ S+ E + + E S++ +++ PE +V E +
Sbjct: 365 MLKISSE-NSNPEQDLKLTSEEESQRFKGSENSQPEKMSQE--PEINKDGDREVEEEM-- 419
Query: 312 SSHEKGN-----RIVNG--QGEGPPAKHPSLKPST------------------EVEDPAV 346
HE N + NG G G P K T E+
Sbjct: 420 KKHESNNVGLLENLTNGVTAGNGDNGLIPQRKSRTPENQQFPDNESEEYHRICELLSDYK 479
Query: 347 KGAVQRKNVQTLRAEQALPVASEEEQQRHERSEKKQPQVK-------------------- 386
+ + + + + EQ L + SEEE QR + SE QP+ +
Sbjct: 480 EKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAI 539
Query: 387 EGNNTNKSEKIQLSENICDSTSSAAAGR----LTQQRKIGKTYPQQFPKKLKEEH----D 438
E ++S + EN+ T+ A AG L RK QQFP EE+
Sbjct: 540 EEMKKHRSTHVGFPENL---TNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQ 596
Query: 439 RCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498
T KQ EE+ N +L+ E L +EKQ +E + + SL K +
Sbjct: 597 NDTQKQFCEEQ-NTGILHD---EILIHEEKQ----IEVVEKMNSELSLSCKKE------- 641
Query: 499 WDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558
K ++ EN L+ +IA+LR E+ TMK+ + +E KYL+DI+ VK+ N L K
Sbjct: 642 ---------KDILHENSTLREEIAMLRLELDTMKHQSQLREKKYLEDIESVKKRNDNLLK 692
Query: 559 YIKLNE 564
++LNE
Sbjct: 693 ALQLNE 698
>gi|134133226 protein expressed in prostate, ovary, testis, and
placenta 2 [Homo sapiens]
Length = 1075
Score = 271 bits (692), Expect = 2e-72
Identities = 206/611 (33%), Positives = 308/611 (50%), Gaps = 102/611 (16%)
Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELDALDKQHRTALHLACASG 78
D + Y +R +L K+HRAA G + + R +++ DKQ RTALHLA A+G
Sbjct: 125 DSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLASANG 184
Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138
+ +VV LL++R+CQ++V D + RT LI+AV CQE+ CA++LLEHG +PN+ D YGNT LH
Sbjct: 185 NSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRL 198
YA+Y+E +A+ LL +GA IE+ +K TPLL + +K+++V+FL+KKKA+ +A+DR
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258
R+AL+LAV S IV++LL+QNIDV +QD+ G+ A +YA+S H I Q + ++K+K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPL--------- 309
+ K S+ S+ E + + E S++ PEK+S+ L
Sbjct: 365 MLKISSE-NSNPEQELKLTSEEESQRFKGSENSQ---------PEKMSQELEINKDGDRE 414
Query: 310 ---PGSSHEKGN-----RIVNG--QGEGPPAKHPSLKPST------------------EV 341
HE N + NG G G P K T E+
Sbjct: 415 VEEEMKKHESNNVGLLENLTNGVTAGNGDNGLIPQRKSRTPENQQFPDNESEEYHRICEL 474
Query: 342 EDPAVKGAVQRKNVQTLRAEQALPVASEEEQQRHERSEKKQPQVK--------------- 386
+ + + + + EQ L + SEEE QR + SE QP+ +
Sbjct: 475 LSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELE 534
Query: 387 -----EGNNTNKSEKIQLSENICDSTSSAAAGR----LTQQRKIGKTYPQQFPKKLKEEH 437
E + S + EN+ T+ A AG L RK QQFP EE+
Sbjct: 535 NFMAIEEMKKHGSTHVGFPENL---TNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEY 591
Query: 438 ----DRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTA 493
T KQ EE+ N +L+ E L +EKQ +E + + SL K +
Sbjct: 592 HSDEQNDTQKQFCEEQ-NTGILHD---EILIHEEKQ----IEVVEKMNSELSLSCKKE-- 641
Query: 494 RNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETN 553
K ++ EN L+ +IA+LR E+ TMK+ + +E KYL+DI+ VK+ N
Sbjct: 642 --------------KDVLHENSTLREEIAMLRLELDTMKHQSQLREKKYLEDIESVKKKN 687
Query: 554 AALEKYIKLNE 564
L K ++LNE
Sbjct: 688 DNLLKALQLNE 698
>gi|222537750 ankyrin repeat domain 30B [Homo sapiens]
Length = 1392
Score = 270 bits (689), Expect = 5e-72
Identities = 181/545 (33%), Positives = 297/545 (54%), Gaps = 30/545 (5%)
Query: 283 DSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVE 342
D+ SD + ++V+ Q E LP ++++K + NG+ E P K +P+TE++
Sbjct: 869 DTKSTSDSEIISVSDTQNY-----ECLPEATYQKEIKTTNGKIEESPEKPSHFEPATEMQ 923
Query: 343 DPAVKGAVQRKNVQTLRAEQALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSEN 402
+ ++ KN QTLRA+ + ER ++K+ N + K++ ++N
Sbjct: 924 NSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGR----ELKKDNCEQITAKMEQTKN 979
Query: 403 ICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRC----TLKQENEEKTNVNMLYKK 458
L++ ++I Q K K E + C TL QE E++ NV++L +K
Sbjct: 980 ----KFCVLQKELSEAKEIKSQLENQ---KAKWEQELCSVRLTLNQEEEKRRNVDILKEK 1032
Query: 459 NREELERKEKQYKKEVEAKQ-LEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCIL 517
R E +Q +K++E KQ LE T++ +++ K+ + N H HE L ENC+L
Sbjct: 1033 IRPE-----EQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCML 1087
Query: 518 KADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQE 577
K +IA+L+ E+ T+K+ + KENKY +DIKI++E NA L+ +KL ++ +T+ A +Y+++
Sbjct: 1088 KKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQYREQ 1147
Query: 578 LNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERT 637
L L AENT L ++L KEK+ K+ LE +IES+ RLA+A+ H +SV + +N +LA
Sbjct: 1148 LKVLTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELAFHSA 1206
Query: 638 QDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQN 697
D +Q M+ +S NE L + L E Q K + K D LR+ +L E Q
Sbjct: 1207 GDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALVSEHAQR 1266
Query: 698 NLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDH 757
+ +TQ Q ++ + MYQN + V+ T + +E+++ L+ +N WL QQL H+K +
Sbjct: 1267 DRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYAHKKVNK 1326
Query: 758 KEIVTNIQRGFIESGKKDFVLEEKSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYFQ 817
++ NIQ K L EK++++ N +HLKE + QYE+EK E VSIK+ KYF
Sbjct: 1327 SKVTINIQ---FPEMKMQRHLNEKNEEVFNYGNHLKERIDQYEKEKAEREVSIKKYKYFS 1383
Query: 818 TSRKK 822
K+
Sbjct: 1384 NFLKE 1388
Score = 225 bits (573), Expect = 1e-58
Identities = 183/547 (33%), Positives = 276/547 (50%), Gaps = 63/547 (11%)
Query: 5 GFGSRRGQTAQGSIDHVYTGSGY-RIRDSELQKIHRAAVKGDAAEVERC-LARRSGELDA 62
G G R + + VYT Y I +L KIH AA +G ++E+ + ++ L+
Sbjct: 9 GKGVRGPEPPNPFSERVYTEKDYGTIYFGDLGKIHTAASRGQVQKLEKMTVGKKPVNLNK 68
Query: 63 LDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEH 122
D + RTALH AC +GH +VVT LV+RKCQ++V D E RTPL++A+ C+ EACA IL++
Sbjct: 69 RDMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDA 128
Query: 123 GANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMV 182
GA+ N D+YGNTALHYAVYSE+ + LLS+GA IE +K + TPLL AI + ++ V
Sbjct: 129 GADLNYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTV 188
Query: 183 EFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISH 242
EFLL K A+++A + + +ALMLA+ S IV +LL+QN+DVFA+D+ G AE YA +
Sbjct: 189 EFLLTKNANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGITAERYAAAC 248
Query: 243 HLTKIQQQILEHKKKILKK------EKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVA 296
+ I QQ+LEH +K+ K E + G+ DE+A E D+ + +K + A
Sbjct: 249 GVNYIHQQLLEHIRKLPKNPQNTNPEGTSTGTPDEAAP--LAERTPDTAESLLEKTPDEA 306
Query: 297 TK---------QCVPEKVSEPLPGSSHEKGNRIVNGQGEGP-----PAKHPSLKPSTEVE 342
+ QC+ + S S+ E +I+ E PAK S K + E +
Sbjct: 307 ARLVEGTSAKIQCLGKATSGKFEQSTEETPRKILRPTKETSEKFSWPAKERSRKITWEEK 366
Query: 343 DPAVK----GAVQRKNVQTLRAEQALPVASEEEQQRHERSEKKQPQVKE------GNNT- 391
+ +VK V + L + +A ++ + S E G T
Sbjct: 367 ETSVKTECVAGVTPNKTEVLEKGTSNMIACPTKETSTKASTNVDVSSVEPIFSLFGTRTI 426
Query: 392 --NKSEKIQLSENICDSTSSAAAGR-------LTQQRKI----GKTYPQQFPKKLKEEHD 438
++ K++ N+ S +A + T Q+ I K Q FP + K E D
Sbjct: 427 ENSQCTKVEEDFNLATKIISKSAAQNYTCLPDATYQKDIKTINHKIEDQMFPSESKREED 486
Query: 439 R-----CTLKQENEEKTNV---NMLYKK----NR--EELERKEKQYKKEVEAKQLEPTVQ 484
E+ KT V +Y+K NR EEL K +K VE ++ P +
Sbjct: 487 EEYSWDSGSLFESSAKTQVCIPESMYQKVMEINREVEELPEKPSAFKPAVEMQKTVPN-K 545
Query: 485 SLEMKSK 491
+ E+K++
Sbjct: 546 AFELKNE 552
Score = 54.3 bits (129), Expect = 5e-07
Identities = 117/596 (19%), Positives = 228/596 (38%), Gaps = 87/596 (14%)
Query: 297 TKQCVPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQ 356
T+ C+PE + + + +N + E P K + KP+ E++ A + KN Q
Sbjct: 503 TQVCIPESMYQKVME---------INREVEELPEKPSAFKPAVEMQKTVPNKAFELKNEQ 553
Query: 357 TLRAEQALPVASEEEQQRHERSEKKQP-------QVKEGNNTNKSEKIQLSENICDSTSS 409
TLRA Q P S+++ + + P V T++ E LS + +S
Sbjct: 554 TLRAAQMFPSESKQKDDEENSWDSESPCETVSQKDVYLPKATHQKEFDTLSGKLEESPVK 613
Query: 410 AAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNV-------------NMLY 456
+ T RK+ P K E DR T K E+ +K + L
Sbjct: 614 DGLLKPTCGRKV------SLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALE 667
Query: 457 KKNREELE---------------RKEKQYKKEVEAKQLE--PTVQSLEMKSKTARNTPN- 498
K+RE L+ RK K +E K E Q +SK + N
Sbjct: 668 LKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQKDDEENS 727
Query: 499 WDFHNHEEMKGLMDENCILKA-----------------DIAILRQEICTMKNDNLEKENK 541
WDF + E L ++ C+ KA D L + C MK +L +
Sbjct: 728 WDFESFLETL-LQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMK-ISLPNKAL 785
Query: 542 YLKDIKIVK-ETNAALEKYIKLNEEMITET--AFRYQQELNDLKAENTRLNAELLKEKES 598
LKD + K E +++E L + TE + + +++ N E +E++
Sbjct: 786 ELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLTTKEGATKTVTGQQERDI 845
Query: 599 KKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQ------DVSVQVEMSSAISK 652
A + + + + ++ T + +++ TQ + + Q E+ + K
Sbjct: 846 GIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNGK 905
Query: 653 VKDENEFLTEQLSETQIKFNALKDKFR--KTRDSLRKKSLALETVQNNLSQTQQQTQEMK 710
+++ E + T+++ N++ +K K + +LR S L + + L ++ + K
Sbjct: 906 IEESPEKPSHFEPATEMQ-NSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKK 964
Query: 711 EMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQ---RG 767
+ + AK+ + K+ +++ + + + L Q Q+ + N + R
Sbjct: 965 DNCEQITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRR 1024
Query: 768 FIESGKKDFVLEEKSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYFQTSRKKI 823
++ K+ EE+ +K + L+++L + E V ++ + + S +
Sbjct: 1025 NVDILKEKIRPEEQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDL 1080
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 268 bits (684), Expect = 2e-71
Identities = 185/492 (37%), Positives = 272/492 (55%), Gaps = 71/492 (14%)
Query: 397 IQLSENICDSTS----------SAAAGRLTQQRKIGKTYPQQFPKKLKEEHD-RCTLKQE 445
++L N CD + S L++ +K Q + KE +D R LKQE
Sbjct: 649 LKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQE 708
Query: 446 NEEKTNVNMLYKKNREELERKEKQYKKEVEAKQ-LEPTVQSLEMKSKTARNTPNWDF--- 501
NEEK N +MLY K+ E+L KE++ K VE KQ L+ ++ L + +T RN N D
Sbjct: 709 NEEKRNADMLYNKDSEQLRIKEEECGKVVETKQQLKWNLRRLVKELRTVRN--NLDLVVQ 766
Query: 502 ------------------------------------------HNHEEMKGLMDENCILKA 519
H H++ K L E+C+L+
Sbjct: 767 ERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNSEISHRHQKEKDLFHEDCMLQE 826
Query: 520 DIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELN 579
+IA+LR EI T+KN N +KE KY +DI+ VKE N L+K IKLNEE +TET +Y +LN
Sbjct: 827 EIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLN 886
Query: 580 DLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQD 639
+L AEN LN+EL K++++RLE ++ESY+ RLAAA+ +S +T R+LKL +RT+
Sbjct: 887 NLTAENKILNSELENGKQNQERLEIEMESYRCRLAAAVRDCDQS-QTARDLKLDFQRTRQ 945
Query: 640 --VSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQN 697
V + +M +S ++ +NE L+E+LS + K N+L+ + TRD+L ++SL LE VQ
Sbjct: 946 EWVRLHDKMKVDMSGLQAKNEILSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQR 1005
Query: 698 NLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDH 757
+LSQTQ Q +E ++MYQ ++K+ K VEER+ LQ EN L QQLDD H+K +
Sbjct: 1006 DLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANS 1065
Query: 758 KEIVTN-IQRGF--------IESGKKDFVLEEKSKKLMNECDHLKESLFQYEREKTEVVV 808
+E ++ IQ F ES K+ L+EK+K+LM+E +HLKE + Q E+EK +
Sbjct: 1066 QEKTSSTIQDQFHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKI 1125
Query: 809 SIKEDKYFQTSR 820
+ E + SR
Sbjct: 1126 DLTEAQETVPSR 1137
Score = 56.2 bits (134), Expect = 1e-07
Identities = 101/472 (21%), Positives = 195/472 (41%), Gaps = 82/472 (17%)
Query: 363 ALPVASEEEQQRHERSEKKQPQVKEGNNTN---------KSEKIQLSENICD------ST 407
+LP S+ + + E +Q K N N K E +QL +++ + S
Sbjct: 478 SLPPDSDRTSEVYLHEELQQDMQKFKNEVNTLEEEFLALKKEDVQLHKDVEEEMEKHRSN 537
Query: 408 SSAAAGRLTQQRKIGKT---YPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELE 464
S+ +G LT +G QQ P+K EHDR K NE+ N +Y E +
Sbjct: 538 STELSGTLTDGTTVGNDDDGLNQQIPRKENGEHDRPADKTSNEKNEVKNQIY----PEAD 593
Query: 465 RKEKQYKKEVEAKQLEPT----------VQSLEMKSKTARNTPNWDFHNHEEMKGLMDEN 514
+ E+ ++ E + ++ L M+ K + + P + D
Sbjct: 594 FADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPR-----------IQDTF 642
Query: 515 CILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRY 574
C+ + + L+ C D L + K ++++ V + + K KL E+ +
Sbjct: 643 CLCE-HLLKLKNNHC----DQLTVKLKQMENMVSVLQNELSETKKTKLQLEL---QKIEW 694
Query: 575 QQELND----LKAEN-TRLNAELLKEKESKK-RLEAD----IESYQSRLAAAISKHSESV 624
++EL D LK EN + NA++L K+S++ R++ + + + +L + + + +
Sbjct: 695 EKELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKVVETKQQLKWNLRRLVKEL 754
Query: 625 KTER-NLKLALERTQDVSVQV--EMSSAI-------SKVKDENEFLTEQLSETQIKFNAL 674
+T R NL L ++ D Q+ E + I SK K+ + SE +
Sbjct: 755 RTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNSEISHRHQKE 814
Query: 675 KDKFRK---TRDSLRKKSLALETVQNNLSQTQ----QQTQEMKEMYQNAE--AKVNNSTG 725
KD F + ++ + L ++T++N Q + + + +KE N + K+N T
Sbjct: 815 KDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETL 874
Query: 726 KWNCVE--ERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKD 775
++ ++ +L EN L +L++ Q ++ EI R + + +D
Sbjct: 875 TETILQYSGQLNNLTAENKILNSELENGKQNQERLEIEMESYRCRLAAAVRD 926
Score = 31.2 bits (69), Expect = 4.1
Identities = 15/32 (46%), Positives = 21/32 (65%)
Query: 353 KNVQTLRAEQALPVASEEEQQRHERSEKKQPQ 384
+N ++ AEQ + SEEEQ+R + E KQPQ
Sbjct: 215 ENKESKEAEQDSELTSEEEQERLKGCENKQPQ 246
>gi|88953571 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 isoform 2 [Homo sapiens]
Length = 1075
Score = 266 bits (679), Expect = 8e-71
Identities = 204/606 (33%), Positives = 308/606 (50%), Gaps = 92/606 (15%)
Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELDALDKQHRTALHLACASG 78
D + Y +R +L K+HRAA G A + + R +++ DKQ RTALHLA A+G
Sbjct: 125 DSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANG 184
Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138
+ VV LL++R+CQ++V D + RT L +AV CQE+ CA++LLEHG +PN+ D YGNT LH
Sbjct: 185 NSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRL 198
YA+Y+E +A+ LL +GA IE+ +K TPLL + +K+++V+FL+KKKA+ +A+DR
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258
R+AL+LAV S IV++LL+QNIDV +QD+ G+ A +YA+S H I Q + ++K+K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPE-------KVSEPLPG 311
+ K S+ S+ E + + E S++ +++ PE +V E +
Sbjct: 365 MLKISSE-NSNPEQDLKLTSEEESQRFKGSENSQPEKMSQE--PEINKDGDREVEEEM-- 419
Query: 312 SSHEKGN-----RIVNG--QGEGPPAKHPSLKPST------------------EVEDPAV 346
HE N + NG G G P K T E+
Sbjct: 420 KKHESNNVGLLENLSNGVTAGNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYK 479
Query: 347 KGAVQRKNVQTLRAEQALPVASEEEQQRHERSEKKQPQVK-------------------- 386
+ + + + + EQ L + SEEE QR + SE QP+ +
Sbjct: 480 EKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAI 539
Query: 387 EGNNTNKSEKIQLSENICDSTSSAAAGR----LTQQRKIGKTYPQQFPKKLKEEH----D 438
E + S + EN+ T+ A AG L RK QQFP EE+
Sbjct: 540 EEMKKHGSTHVGFPENL---TNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQ 596
Query: 439 RCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498
T KQ EE+ N +L+ E L +EKQ +E + + SL K +
Sbjct: 597 NDTQKQFCEEQ-NTGILHD---EILIHEEKQ----IEVVEKMNSELSLSCKKE------- 641
Query: 499 WDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558
K + EN L+ +IA+LR E+ TMK+ + ++ KYL+DI+ VK+ N L K
Sbjct: 642 ---------KDFLHENSTLREEIAMLRLELDTMKHQSQLRKKKYLEDIESVKKKNDNLLK 692
Query: 559 YIKLNE 564
++LNE
Sbjct: 693 ALQLNE 698
>gi|113413200 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 [Homo sapiens]
Length = 1038
Score = 265 bits (678), Expect = 1e-70
Identities = 203/606 (33%), Positives = 308/606 (50%), Gaps = 92/606 (15%)
Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELDALDKQHRTALHLACASG 78
D + Y +R +L K+HRAA G A + + R +++ DKQ RTALHLA A+G
Sbjct: 88 DSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANG 147
Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138
+ VV LL++R+CQ++V D + RT L +AV CQE+ CA++LLEHG +PN+ D YGNT LH
Sbjct: 148 NSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 207
Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRL 198
YA+Y+E +A+ LL +GA IE+ +K TPLL + +K+++V+FL+KKKA+ +A+DR
Sbjct: 208 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 267
Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258
R+AL+LAV S IV++LL+QNIDV +QD+ G+ A +YA+S H I Q + ++K+K
Sbjct: 268 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 327
Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPE-------KVSEPLPG 311
+ K S+ S+ E + + E S++ +++ PE +V E +
Sbjct: 328 MLKISSE-NSNPEQDLKLTSEEESQRFKGSENSQPEKMSQE--PEINKDGDREVEEEM-- 382
Query: 312 SSHEKGN-----RIVNG--QGEGPPAKHPSLKPST------------------EVEDPAV 346
HE N + NG G G P K T E+
Sbjct: 383 KKHESNNVGLLENLSNGVTAGNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYK 442
Query: 347 KGAVQRKNVQTLRAEQALPVASEEEQQRHERSEKKQPQVK-------------------- 386
+ + + + + EQ L + SEEE QR + SE QP+ +
Sbjct: 443 EKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAI 502
Query: 387 EGNNTNKSEKIQLSENICDSTSSAAAGR----LTQQRKIGKTYPQQFPKKLKEEH----D 438
E + S + EN+ T+ A AG L RK QQFP EE+
Sbjct: 503 EEMKKHGSTHVGFPENL---TNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQ 559
Query: 439 RCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498
T KQ EE+ N +L+ E L +EKQ + +E L + K R+
Sbjct: 560 NDTQKQFCEEQ-NTGILHD---EILIHEEKQIEV------VEKMNSELSLSCKKERD--- 606
Query: 499 WDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558
+ EN +L+ +IA+LR E+ TMK+ + ++ KYL+DI+ VK+ N L K
Sbjct: 607 -----------FLHENSMLREEIAMLRLELDTMKHQSQLRKKKYLEDIESVKKKNDNLLK 655
Query: 559 YIKLNE 564
++LNE
Sbjct: 656 ALQLNE 661
>gi|239741769 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 [Homo sapiens]
Length = 952
Score = 248 bits (632), Expect = 2e-65
Identities = 182/550 (33%), Positives = 282/550 (51%), Gaps = 103/550 (18%)
Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELDALDKQHRTALHLACASG 78
D + Y +R +L K+HRAA G A + + R +++ DKQ RTALHLA A+G
Sbjct: 125 DSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANG 184
Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138
+ VV LL++R+CQ++V D + RT L +AV CQE+ CA++LLEHG +PN+ D YGNT LH
Sbjct: 185 NSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244
Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRL 198
YA+Y+E +A+ LL +GA IE+ +K TPLL + +K+++V+FL+KKKA+ +A+DR
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258
R+AL+LAV S IV++LL+QNIDV +QD+ G+ A +YA+S H I Q + ++K+K
Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364
Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGN 318
+ L++ S ++ ++DL + + E+ S+ GS +
Sbjct: 365 M--------------------LKISSENSNPEQDLKLTS-----EEESQRFKGSENS--- 396
Query: 319 RIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQQRHERS 378
+P ++P + R+ EEE ++H +
Sbjct: 397 -----------------QPEKMSQEPEINKDGDRE--------------VEEEMKKHGST 425
Query: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEH- 437
P+ N TN +T+ L RK QQFP EE+
Sbjct: 426 HVGFPE----NLTN------------GATAGNGDDGLIPPRKSRTPESQQFPDTENEEYH 469
Query: 438 ---DRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTAR 494
T KQ EE+ N +L+ E L +EKQ +E + + SL K +
Sbjct: 470 SDEQNDTQKQFCEEQ-NTGILHD---EILIHEEKQ----IEVVEKMNSELSLSCKKE--- 518
Query: 495 NTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNA 554
K + EN L+ +IA+LR E+ TMK+ + ++ KYL+DI+ VK+ N
Sbjct: 519 -------------KDFLHENSTLREEIAMLRLELDTMKHQSQLRKKKYLEDIESVKKKND 565
Query: 555 ALEKYIKLNE 564
L K ++LNE
Sbjct: 566 NLLKALQLNE 575
>gi|239741786 PREDICTED: kappa-actin [Homo sapiens]
Length = 924
Score = 245 bits (626), Expect = 1e-64
Identities = 186/554 (33%), Positives = 284/554 (51%), Gaps = 102/554 (18%)
Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELDALDKQHRTALHLACASG 78
D + Y + +L K+HRAA G + + R +++ DKQ RTALHLA A+G
Sbjct: 88 DSAFMDPRYHVHGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKRDKQKRTALHLASANG 147
Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138
+ +VV L+++R+CQ++V D + RT L +AV CQE+ CA++LLEHG +PN+ D YGNT LH
Sbjct: 148 NSEVVKLVLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 207
Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRL 198
YAVY+E +A+ LL +GA IE+ +K TPLL I +K+++V+FL+KKKA+ +A+DR
Sbjct: 208 YAVYNEDKLMAKALLLYGADIESKNKHGLTPLLLGIHEQKQQVVKFLIKKKANLNALDRY 267
Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258
R+AL+LAV S IV+ LL+QNIDV +QD G+ A +YA+S H I Q + ++K+K
Sbjct: 268 GRTALILAVCCGSANIVSPLLEQNIDVSSQD-XGQTAREYAVSSHHHVICQLLSDYKEKQ 326
Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGN 318
+ K S+ S+ E + + E L S++ PEK+S+
Sbjct: 327 MLKISSE-NSNPEQDLKLTSEEESQKLKGSENSQ---------PEKMSQ----------E 366
Query: 319 RIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQQRHERS 378
+N G+ E+ED +A EEE ++H
Sbjct: 367 PEINKDGD------------RELED---------------------FMAIEEEMKKH--- 390
Query: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGR----LTQQRKIGKTYPQQFPKKLK 434
S + EN+ T+ AAAG L RK QQFP
Sbjct: 391 --------------GSTHVGFPENL---TNGAAAGNGDDGLIPPRKSRTPESQQFPDTEN 433
Query: 435 EEH----DRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKS 490
EE+ T KQ +EE+ N +L E L +EKQ +E+
Sbjct: 434 EEYHSDEQNDTQKQLSEEQ-NTGIL---QDEILXHEEKQ----------------IEVAE 473
Query: 491 KTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVK 550
K + P ++++ K + EN L+ ++A+LR E+ MK+ + +E KYL++I+ V+
Sbjct: 474 KKMNSGPGTLSLSYKKEKDFLHENSTLQEEVAMLRLELDIMKHQSQLREKKYLEEIESVE 533
Query: 551 ETNAALEKYIKLNE 564
+ N L K ++LNE
Sbjct: 534 KKNDNLLKALQLNE 547
>gi|239753333 PREDICTED: actin, beta-like 3 [Homo sapiens]
Length = 924
Score = 245 bits (625), Expect = 1e-64
Identities = 185/554 (33%), Positives = 284/554 (51%), Gaps = 102/554 (18%)
Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELDALDKQHRTALHLACASG 78
D + Y + +L K+HRAA G + + R +++ DKQ RTALHLA A+G
Sbjct: 88 DSAFMDPRYHVHGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKRDKQKRTALHLASANG 147
Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138
+ +VV L+++R+CQ++V D + RT L +AV CQE+ CA++LLEHG +PN+ D YGNT LH
Sbjct: 148 NSEVVKLVLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 207
Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRL 198
YAVY+E +A+ LL +GA IE+ +K TPLL I +K+++V+FL+KKKA+ +A+DR
Sbjct: 208 YAVYNEDKLMAKALLLYGADIESKNKHGLTPLLLGIHEQKQQVVKFLIKKKANLNALDRY 267
Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258
R+AL+LAV S IV+ LL+QN+DV +QD G+ A +YA+S H I Q + ++K+K
Sbjct: 268 GRTALILAVCCGSASIVSPLLEQNVDVSSQD-XGKTAREYAVSSHHHVICQLLSDYKEKQ 326
Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGN 318
+ K S+ S+ E + + E L S++ PEK+S+
Sbjct: 327 MLKISSE-NSNPEQDLKLTSEEESQRLKGSENSQ---------PEKMSQ----------E 366
Query: 319 RIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQQRHERS 378
+N G+ E+ED +A EEE ++H
Sbjct: 367 PEINKDGD------------RELED---------------------FMAIEEEMKKH--- 390
Query: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGR----LTQQRKIGKTYPQQFPKKLK 434
S + EN+ T+ AAAG L RK QQFP
Sbjct: 391 --------------GSTHVGFPENL---TNGAAAGNGDDGLIPPRKSRTPESQQFPDTEN 433
Query: 435 EEH----DRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKS 490
EE+ T KQ +EE+ N +L E L +EKQ +E+
Sbjct: 434 EEYHSDEQNDTQKQLSEEQ-NTGIL---QDEILXHEEKQ----------------IEVAE 473
Query: 491 KTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVK 550
K + P ++++ K + EN L+ ++A+LR E+ MK+ + +E KYL++I+ V+
Sbjct: 474 KKMNSGPGTLSLSYKKEKDFLHENSTLQEEVAMLRLELDIMKHQSQLREKKYLEEIESVE 533
Query: 551 ETNAALEKYIKLNE 564
+ N L K ++LNE
Sbjct: 534 KKNDNLLKALQLNE 547
>gi|239747898 PREDICTED: actin, beta-like 3 [Homo sapiens]
Length = 924
Score = 245 bits (625), Expect = 1e-64
Identities = 185/554 (33%), Positives = 284/554 (51%), Gaps = 102/554 (18%)
Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELDALDKQHRTALHLACASG 78
D + Y + +L K+HRAA G + + R +++ DKQ RTALHLA A+G
Sbjct: 88 DSAFMDPRYHVHGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKRDKQKRTALHLASANG 147
Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138
+ +VV L+++R+CQ++V D + RT L +AV CQE+ CA++LLEHG +PN+ D YGNT LH
Sbjct: 148 NSEVVKLVLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 207
Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRL 198
YAVY+E +A+ LL +GA IE+ +K TPLL I +K+++V+FL+KKKA+ +A+DR
Sbjct: 208 YAVYNEDKLMAKALLLYGADIESKNKHGLTPLLLGIHEQKQQVVKFLIKKKANLNALDRY 267
Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258
R+AL+LAV S IV+ LL+QN+DV +QD G+ A +YA+S H I Q + ++K+K
Sbjct: 268 GRTALILAVCCGSASIVSPLLEQNVDVSSQD-XGKTAREYAVSSHHHVICQLLSDYKEKQ 326
Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGN 318
+ K S+ S+ E + + E L S++ PEK+S+
Sbjct: 327 MLKISSE-NSNPEQDLKLTSEEESQRLKGSENSQ---------PEKMSQ----------E 366
Query: 319 RIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQQRHERS 378
+N G+ E+ED +A EEE ++H
Sbjct: 367 PEINKDGD------------RELED---------------------FMAIEEEMKKH--- 390
Query: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGR----LTQQRKIGKTYPQQFPKKLK 434
S + EN+ T+ AAAG L RK QQFP
Sbjct: 391 --------------GSTHVGFPENL---TNGAAAGNGDDGLIPPRKSRTPESQQFPDTEN 433
Query: 435 EEH----DRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKS 490
EE+ T KQ +EE+ N +L E L +EKQ +E+
Sbjct: 434 EEYHSDEQNDTQKQLSEEQ-NTGIL---QDEILXHEEKQ----------------IEVAE 473
Query: 491 KTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVK 550
K + P ++++ K + EN L+ ++A+LR E+ MK+ + +E KYL++I+ V+
Sbjct: 474 KKMNSGPGTLSLSYKKEKDFLHENSTLQEEVAMLRLELDIMKHQSQLREKKYLEEIESVE 533
Query: 551 ETNAALEKYIKLNE 564
+ N L K ++LNE
Sbjct: 534 KKNDNLLKALQLNE 547
>gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo
sapiens]
Length = 498
Score = 241 bits (614), Expect = 3e-63
Identities = 141/344 (40%), Positives = 210/344 (61%), Gaps = 20/344 (5%)
Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELDALDKQHRTALHLACASG 78
D +T Y +R +L K+HRAA G+ + + R ++ DK+ RTALHLACA+G
Sbjct: 51 DSAFTEPRYHVRREDLGKLHRAAWWGEVPRADLIVMLRGPGINKRDKKKRTALHLACANG 110
Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138
+ +VV+LL++R+CQ+ V D + RT LI+AV CQE+ CA++LL+HG +PNL D+YGNTALH
Sbjct: 111 NSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECALMLLQHGTDPNLPDMYGNTALH 170
Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRL 198
YAVY+E +A+ LL +GA IE+ +K TPLL A+ +K++MV+FL+KKKA+ +A+DR
Sbjct: 171 YAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQKQRMVKFLIKKKANLNALDRF 230
Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258
R+AL+LAV S IV++LL+QNIDVF+QD+ G+ AEDYA+S H + I Q + ++K+
Sbjct: 231 GRTALILAVRCGSASIVSLLLQQNIDVFSQDVFGQTAEDYAVSSHHSIICQLLSDYKENQ 290
Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVAT------KQCVPEKVSEPLPGS 312
+ S S+ E + + E L S++ T K C E E
Sbjct: 291 MPNNSSG-NSNPEQDLKLTSEEEPQRLKGSENSQHEKVTQEPDINKDCDREVEEEMQKHG 349
Query: 313 SHEKG------NRIVNGQGEG------PPAKHPSLK-PSTEVED 343
S+ G + G G+G KH + + P+TE+E+
Sbjct: 350 SNNVGLSENLTDGAAAGNGDGGLVPQRKSRKHENQQFPNTEIEE 393
>gi|52856430 protein expressed in prostate, ovary, testis, and
placenta 15 [Homo sapiens]
Length = 581
Score = 234 bits (596), Expect = 3e-61
Identities = 176/553 (31%), Positives = 280/553 (50%), Gaps = 97/553 (17%)
Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGELDALDKQHRTALHLACASG 78
D + Y +R +L K+HRAA G + + R +++ DKQ RTALHLA A+G
Sbjct: 125 DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANG 184
Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138
+ +VV LL++R+CQ++V D + RT LI+AV CQE+ C ++LLEHGA+ N++D YGNTALH
Sbjct: 185 NSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALH 244
Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRL 198
YA+Y+E +A+ LL +GA IE+ +K TPLL + +K+++V+FL+KKKA+ +A+DR
Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304
Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258
R+AL+LAV S IVN+LL+QN+DV +QD+ G+ A +YA+S H I + + ++K+K
Sbjct: 305 GRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQ 364
Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGN 318
+ K S+ S+ E + + E L S++ PEK+S+ + N
Sbjct: 365 MLKISSE-NSNPEQDLKLTSEEESQRLKVSENSQ---------PEKMSQ------EPEIN 408
Query: 319 RIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQQRHERS 378
+ + + E KH S + + GA L ++ + + E Q+ +
Sbjct: 409 KDCDREVEEEIKKHGS--NPVGLPENLTNGASAGNGDDGLIPQRK---SRKPENQQFPDT 463
Query: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHD 438
E ++ E N+T K QLSE +T + LT ++K + ++ KL H
Sbjct: 464 ENEEYHSDEQNDTQK----QLSEE--QNTGISQDEILTNKQKQIEVAEKEMNSKLSLSH- 516
Query: 439 RCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498
K E+L R+ ++E+ +LE
Sbjct: 517 -------------------KKEEDLLRENSMLREEIAMLRLE------------------ 539
Query: 499 WDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558
+DE K+ N +ENK L++I+ VKE L K
Sbjct: 540 ------------LDET-----------------KHQNQLRENKILEEIESVKE---KLLK 567
Query: 559 YIKLNEEMITETA 571
I+LNEE +T+T+
Sbjct: 568 AIQLNEEALTKTS 580
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,134,029
Number of Sequences: 37866
Number of extensions: 1361425
Number of successful extensions: 14159
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 493
Number of HSP's successfully gapped in prelim test: 1036
Number of HSP's that attempted gapping in prelim test: 6676
Number of HSP's gapped (non-prelim): 4946
length of query: 823
length of database: 18,247,518
effective HSP length: 111
effective length of query: 712
effective length of database: 14,044,392
effective search space: 9999607104
effective search space used: 9999607104
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.