Guide to the Human Genome
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Search of human proteins with 149274624

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|149274624 limb bud and heart development homolog [Homo
sapiens]
         (105 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|149274624 limb bud and heart development homolog [Homo sapiens]    223   2e-59
gi|46198301 hypothetical protein LOC79081 [Homo sapiens]               38   0.001
gi|55770852 glutamate receptor, ionotropic, delta 1 precursor [H...    29   0.69 
gi|93141033 PAX interacting protein 1 [Homo sapiens]                   28   1.5  
gi|6978649 choline kinase beta [Homo sapiens]                          28   2.0  
gi|38016937 lemur tyrosine kinase 2 [Homo sapiens]                     28   2.0  
gi|47578117 DEP domain containing 2 isoform b [Homo sapiens]           28   2.0  
gi|47578115 DEP domain containing 2 isoform a [Homo sapiens]           28   2.0  
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear...    27   2.6  
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear...    27   2.6  
gi|122114654 methyltransferase 10 domain containing [Homo sapiens]     27   3.4  
gi|22547191 sorting nexin 15 isoform A [Homo sapiens]                  27   4.5  
gi|13376339 plasticity-related protein 2 [Homo sapiens]                27   4.5  
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    27   4.5  
gi|223278381 ribosomal RNA processing 12 homolog isoform 2 [Homo...    26   5.9  
gi|223278379 ribosomal RNA processing 12 homolog isoform 1 [Homo...    26   5.9  
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i...    26   5.9  
gi|18375648 protein tyrosine phosphatase, non-receptor type 13 i...    26   5.9  
gi|18375646 protein tyrosine phosphatase, non-receptor type 13 i...    26   5.9  
gi|5453992 protein tyrosine phosphatase, non-receptor type 13 is...    26   5.9  
gi|186928821 hepatoma-derived growth factor isoform c [Homo sapi...    26   5.9  
gi|186928819 hepatoma-derived growth factor isoform b [Homo sapi...    26   5.9  
gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]     26   5.9  
gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]         26   5.9  
gi|50557648 zinc finger, FYVE domain containing 27 isoform c [Ho...    26   7.7  
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]    26   7.7  
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]        26   7.7  
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]            26   7.7  
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]        26   7.7  
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami...    26   7.7  

>gi|149274624 limb bud and heart development homolog [Homo sapiens]
          Length = 105

 Score =  223 bits (569), Expect = 2e-59
 Identities = 105/105 (100%), Positives = 105/105 (100%)

Query: 1   MSIYFPIHCPDYLRSAKMTEVMMNTQPMEEIGLSPRKDGLSYQIFPDPSDFDRCCKLKDR 60
           MSIYFPIHCPDYLRSAKMTEVMMNTQPMEEIGLSPRKDGLSYQIFPDPSDFDRCCKLKDR
Sbjct: 1   MSIYFPIHCPDYLRSAKMTEVMMNTQPMEEIGLSPRKDGLSYQIFPDPSDFDRCCKLKDR 60

Query: 61  LPSIVVEPTEGEVESGELRWPPEEFLVQEDEQDNCEETAKENKEQ 105
           LPSIVVEPTEGEVESGELRWPPEEFLVQEDEQDNCEETAKENKEQ
Sbjct: 61  LPSIVVEPTEGEVESGELRWPPEEFLVQEDEQDNCEETAKENKEQ 105


>gi|46198301 hypothetical protein LOC79081 [Homo sapiens]
          Length = 263

 Score = 38.1 bits (87), Expect = 0.001
 Identities = 21/49 (42%), Positives = 30/49 (61%), Gaps = 1/49 (2%)

Query: 58  KDRLPSIVVEPTEGEVESGELRWPPEEFLVQED-EQDNCEETAKENKEQ 105
           K  LPSIVVE +E   ESG+L  P EE L+  D E+++ E   ++  E+
Sbjct: 55  KSHLPSIVVESSEVNEESGDLHLPHEELLLLTDGEEEDAEAFFQDQSEE 103


>gi|55770852 glutamate receptor, ionotropic, delta 1 precursor [Homo
           sapiens]
          Length = 1009

 Score = 29.3 bits (64), Expect = 0.69
 Identities = 11/32 (34%), Positives = 19/32 (59%)

Query: 43  QIFPDPSDFDRCCKLKDRLPSIVVEPTEGEVE 74
           QIFP   D  +C +   R+ S++ +P EG ++
Sbjct: 283 QIFPSAKDNQKCTRNNHRISSLLCDPQEGYLQ 314


>gi|93141033 PAX interacting protein 1 [Homo sapiens]
          Length = 1069

 Score = 28.1 bits (61), Expect = 1.5
 Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 5/70 (7%)

Query: 41  SYQIFPDPSDFDRCCKLKDR-----LPSIVVEPTEGEVESGELRWPPEEFLVQEDEQDNC 95
           ++ I P+P      C LK        P  V++    + +  E  + P   + +E+E++  
Sbjct: 137 THLIVPEPKGEKYECALKRASIKIVTPDWVLDCVSEKTKKDEAFYHPRLIIYEEEEEEEE 196

Query: 96  EETAKENKEQ 105
           EE   EN+EQ
Sbjct: 197 EEEEVENEEQ 206


>gi|6978649 choline kinase beta [Homo sapiens]
          Length = 395

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 14/62 (22%)

Query: 9   CPDYLRSAKMTEVMMNTQPMEEIGLSPRKDGLSYQIFPDPSDFDRCCKLKDRLPSIVVEP 68
           C +YL  A         QP EE+ + P   GLS  +F         C L D LPS+  EP
Sbjct: 53  CREYLGGA-----WRRVQP-EELRVYPVSGGLSNLLFR--------CSLPDHLPSVGEEP 98

Query: 69  TE 70
            E
Sbjct: 99  RE 100


>gi|38016937 lemur tyrosine kinase 2 [Homo sapiens]
          Length = 1503

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 26/96 (27%), Positives = 35/96 (36%), Gaps = 13/96 (13%)

Query: 13  LRSAKMTEVMMNTQPME----EIGLSPRKDGLSY-----QIFPDPSDF----DRCCKLKD 59
           L++A  TE M+ T        E+  +  K GLS          D +D     D       
Sbjct: 749 LKNAGFTEAMLETSCRNSLDTELQFAENKPGLSLLQENVSTKGDDTDVMLTGDTLSTSLQ 808

Query: 60  RLPSIVVEPTEGEVESGELRWPPEEFLVQEDEQDNC 95
             P + V PT  E E    R PP+    Q + Q  C
Sbjct: 809 SSPEVQVPPTSFETEETPRRVPPDSLPTQGETQPTC 844


>gi|47578117 DEP domain containing 2 isoform b [Homo sapiens]
          Length = 979

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 12/32 (37%), Positives = 19/32 (59%)

Query: 13  LRSAKMTEVMMNTQPMEEIGLSPRKDGLSYQI 44
           L S K   V+++T+P E + +    DGL +QI
Sbjct: 660 LNSRKPLRVLVSTKPRETVKIPDSADGLGFQI 691


>gi|47578115 DEP domain containing 2 isoform a [Homo sapiens]
          Length = 1606

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 12/32 (37%), Positives = 19/32 (59%)

Query: 13  LRSAKMTEVMMNTQPMEEIGLSPRKDGLSYQI 44
           L S K   V+++T+P E + +    DGL +QI
Sbjct: 660 LNSRKPLRVLVSTKPRETVKIPDSADGLGFQI 691


>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 13/38 (34%), Positives = 21/38 (55%)

Query: 67  EPTEGEVESGELRWPPEEFLVQEDEQDNCEETAKENKE 104
           E  EG+ +  E+    EEF + +DE D  E+  +E +E
Sbjct: 218 EDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEE 255


>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 13/38 (34%), Positives = 21/38 (55%)

Query: 67  EPTEGEVESGELRWPPEEFLVQEDEQDNCEETAKENKE 104
           E  EG+ +  E+    EEF + +DE D  E+  +E +E
Sbjct: 218 EDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEE 255


>gi|122114654 methyltransferase 10 domain containing [Homo sapiens]
          Length = 562

 Score = 26.9 bits (58), Expect = 3.4
 Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 10/78 (12%)

Query: 26  QPMEEIGLSPRKDGLSYQIFPDPSDFDRCCKLKDRLPSIVVEPTEGEVESGELRWPPEEF 85
           Q +EE   +P++ G S ++   P +   C       P++     EGE  + E   P +E 
Sbjct: 404 QALEEKKPTPKESGNSQELARGPQERTPCG------PAL----REGEAAAVEGPCPSQES 453

Query: 86  LVQEDEQDNCEETAKENK 103
           L QE+  +  E+   E K
Sbjct: 454 LSQEENPEPTEDERSEEK 471


>gi|22547191 sorting nexin 15 isoform A [Homo sapiens]
          Length = 342

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 5/90 (5%)

Query: 6   PIHCPDYLRSAKMTEVMMNTQPMEEIGLSPRKDGLSYQIFPDPSDFDRCCKLKDRLPSI- 64
           P+  P    + +  +++ N +  EE   SP +  L+     + + FD   K +   PS  
Sbjct: 173 PVDPPPSSPAQEALDLLFNCESTEEASGSPARGPLTEA---ELALFDPFSKEEGAAPSPT 229

Query: 65  -VVEPTEGEVESGELRWPPEEFLVQEDEQD 93
            V E    EVES  L   P E   QE+E+D
Sbjct: 230 HVAELATMEVESARLDQEPWEPGGQEEEED 259


>gi|13376339 plasticity-related protein 2 [Homo sapiens]
          Length = 746

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 11/34 (32%), Positives = 20/34 (58%)

Query: 72  EVESGELRWPPEEFLVQEDEQDNCEETAKENKEQ 105
           +   G LR P E    +E+E+++ EE  +E +E+
Sbjct: 454 DASPGHLRAPAEPMAEEEEEEEDEEEEEEEEEEE 487


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 13/39 (33%), Positives = 23/39 (58%)

Query: 67  EPTEGEVESGELRWPPEEFLVQEDEQDNCEETAKENKEQ 105
           E  EG     E++  PEE   +E+E++  EE+ +E +E+
Sbjct: 516 EKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEE 554


>gi|223278381 ribosomal RNA processing 12 homolog isoform 2 [Homo
            sapiens]
          Length = 1236

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 5/39 (12%)

Query: 67   EPTEGEVESGELRWPPEEFLVQEDEQDNCEETAKENKEQ 105
            EP +G+ +S E     E     EDE+DN EE     KEQ
Sbjct: 1003 EPAQGKGDSIE-----EILADSEDEEDNEEEERSRGKEQ 1036


>gi|223278379 ribosomal RNA processing 12 homolog isoform 1 [Homo
            sapiens]
          Length = 1297

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 5/39 (12%)

Query: 67   EPTEGEVESGELRWPPEEFLVQEDEQDNCEETAKENKEQ 105
            EP +G+ +S E     E     EDE+DN EE     KEQ
Sbjct: 1064 EPAQGKGDSIE-----EILADSEDEEDNEEEERSRGKEQ 1097


>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
            isoform 4 [Homo sapiens]
          Length = 2490

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 14/63 (22%), Positives = 33/63 (52%), Gaps = 6/63 (9%)

Query: 43   QIFPDPSDFDRC---CKLKDRLPSIVVEPTEGEVESGELRWPPEEFLVQEDEQDNCEETA 99
            + F + +  + C   C+ K +  S++ +P E + +  E+ W  +E  +   E+ N E++ 
Sbjct: 2116 EYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPI---ERTNHEDSD 2172

Query: 100  KEN 102
            K++
Sbjct: 2173 KDH 2175


>gi|18375648 protein tyrosine phosphatase, non-receptor type 13
            isoform 3 [Homo sapiens]
          Length = 2294

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 14/63 (22%), Positives = 33/63 (52%), Gaps = 6/63 (9%)

Query: 43   QIFPDPSDFDRC---CKLKDRLPSIVVEPTEGEVESGELRWPPEEFLVQEDEQDNCEETA 99
            + F + +  + C   C+ K +  S++ +P E + +  E+ W  +E  +   E+ N E++ 
Sbjct: 1920 EYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPI---ERTNHEDSD 1976

Query: 100  KEN 102
            K++
Sbjct: 1977 KDH 1979


>gi|18375646 protein tyrosine phosphatase, non-receptor type 13
            isoform 1 [Homo sapiens]
          Length = 2485

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 14/63 (22%), Positives = 33/63 (52%), Gaps = 6/63 (9%)

Query: 43   QIFPDPSDFDRC---CKLKDRLPSIVVEPTEGEVESGELRWPPEEFLVQEDEQDNCEETA 99
            + F + +  + C   C+ K +  S++ +P E + +  E+ W  +E  +   E+ N E++ 
Sbjct: 2111 EYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPI---ERTNHEDSD 2167

Query: 100  KEN 102
            K++
Sbjct: 2168 KDH 2170


>gi|5453992 protein tyrosine phosphatase, non-receptor type 13 isoform
            2 [Homo sapiens]
          Length = 2466

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 14/63 (22%), Positives = 33/63 (52%), Gaps = 6/63 (9%)

Query: 43   QIFPDPSDFDRC---CKLKDRLPSIVVEPTEGEVESGELRWPPEEFLVQEDEQDNCEETA 99
            + F + +  + C   C+ K +  S++ +P E + +  E+ W  +E  +   E+ N E++ 
Sbjct: 2092 EYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPI---ERTNHEDSD 2148

Query: 100  KEN 102
            K++
Sbjct: 2149 KDH 2151


>gi|186928821 hepatoma-derived growth factor isoform c [Homo
           sapiens]
          Length = 233

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 3/39 (7%)

Query: 66  VEPTEGEVESGELRWPPEEFLVQEDEQDNCEETAKENKE 104
           VE      E G  R PP+E   +EDE+   EE  KE+ E
Sbjct: 188 VEKNSTPSEPGSGRGPPQEEEEEEDEE---EEATKEDAE 223


>gi|186928819 hepatoma-derived growth factor isoform b [Homo
           sapiens]
          Length = 256

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 3/39 (7%)

Query: 66  VEPTEGEVESGELRWPPEEFLVQEDEQDNCEETAKENKE 104
           VE      E G  R PP+E   +EDE+   EE  KE+ E
Sbjct: 211 VEKNSTPSEPGSGRGPPQEEEEEEDEE---EEATKEDAE 246


>gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]
          Length = 240

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 3/39 (7%)

Query: 66  VEPTEGEVESGELRWPPEEFLVQEDEQDNCEETAKENKE 104
           VE      E G  R PP+E   +EDE+   EE  KE+ E
Sbjct: 195 VEKNSTPSEPGSGRGPPQEEEEEEDEE---EEATKEDAE 230


>gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]
          Length = 224

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 12/62 (19%), Positives = 30/62 (48%)

Query: 44  IFPDPSDFDRCCKLKDRLPSIVVEPTEGEVESGELRWPPEEFLVQEDEQDNCEETAKENK 103
           + P+ ++FD   +L++         +     S  +  P ++   +E+E++  EE  +E +
Sbjct: 4   LLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEE 63

Query: 104 EQ 105
           E+
Sbjct: 64  EE 65


>gi|50557648 zinc finger, FYVE domain containing 27 isoform c [Homo
           sapiens]
          Length = 404

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 9/66 (13%)

Query: 33  LSPRKDGLSYQIFPDPSDFDRCCKLKDRLPSIVVEPTE----GEVESGELRWPPEEF--L 86
           ++P+++  +++  P P D      L D  P++   PTE    G VE  E   P EEF   
Sbjct: 234 MNPKQEEHAFES-PPPPDVGGKDGLMDSTPALT--PTEDLTPGSVEEAEEAEPDEEFKDA 290

Query: 87  VQEDEQ 92
           ++ED++
Sbjct: 291 IEEDDE 296


>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
          Length = 710

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 14/47 (29%), Positives = 21/47 (44%)

Query: 58  KDRLPSIVVEPTEGEVESGELRWPPEEFLVQEDEQDNCEETAKENKE 104
           KD   +I  E  +GE+        P       DE+D+    A+ENK+
Sbjct: 447 KDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKD 493


>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 948

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 14/47 (29%), Positives = 21/47 (44%)

Query: 58  KDRLPSIVVEPTEGEVESGELRWPPEEFLVQEDEQDNCEETAKENKE 104
           KD   +I  E  +GE+        P       DE+D+    A+ENK+
Sbjct: 619 KDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKD 665


>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 185

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 19/51 (37%), Positives = 25/51 (49%), Gaps = 6/51 (11%)

Query: 55  CKLKDRLPSIVVEPTEGEVESGELRWPPEEFLVQEDEQDNCEETAKENKEQ 105
           C  +  LP   VE  E E E  E+    EE   +E E+D  EE  +E KE+
Sbjct: 110 CSAQQGLP---VEEEEVEEEEEEVE---EEEKEEEKEEDEEEEEKEEEKEE 154


>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 1524

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 14/47 (29%), Positives = 21/47 (44%)

Query: 58  KDRLPSIVVEPTEGEVESGELRWPPEEFLVQEDEQDNCEETAKENKE 104
           KD   +I  E  +GE+        P       DE+D+    A+ENK+
Sbjct: 619 KDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKD 665


>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member E isoform 1 [Homo sapiens]
          Length = 268

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 14/36 (38%), Positives = 19/36 (52%)

Query: 70  EGEVESGELRWPPEEFLVQEDEQDNCEETAKENKEQ 105
           EGE E G      EE   +ED+ D  EE  +E +E+
Sbjct: 211 EGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEE 246


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.134    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,783,814
Number of Sequences: 37866
Number of extensions: 220750
Number of successful extensions: 522
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 485
Number of HSP's gapped (non-prelim): 48
length of query: 105
length of database: 18,247,518
effective HSP length: 76
effective length of query: 29
effective length of database: 15,369,702
effective search space: 445721358
effective search space used: 445721358
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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