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Search of human proteins with 148833511
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148833511 RNA binding motif protein 47 isoform b [Homo
sapiens]
(524 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens] 1058 0.0
gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens] 941 0.0
gi|20357575 apobec-1 complementation factor isoform 2 [Homo sapi... 486 e-137
gi|20357572 apobec-1 complementation factor isoform 1 [Homo sapi... 486 e-137
gi|21450675 RNA binding motif protein 46 [Homo sapiens] 465 e-131
gi|20357578 apobec-1 complementation factor isoform 3 [Homo sapi... 455 e-128
gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4... 355 7e-98
gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2 [... 355 7e-98
gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3... 349 3e-96
gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1... 349 3e-96
gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting ... 340 1e-93
gi|228008396 synaptotagmin binding, cytoplasmic RNA interacting ... 340 1e-93
gi|228008293 synaptotagmin binding, cytoplasmic RNA interacting ... 340 1e-93
gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting ... 340 1e-93
gi|228008398 synaptotagmin binding, cytoplasmic RNA interacting ... 288 1e-77
gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting ... 288 1e-77
gi|34740339 dead end homolog 1 [Homo sapiens] 184 2e-46
gi|93277122 RNA binding motif protein 4 [Homo sapiens] 83 7e-16
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 79 1e-14
gi|13899354 RNA binding motif protein 4B [Homo sapiens] 78 2e-14
gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo sa... 75 1e-13
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 73 6e-13
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 72 9e-13
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 72 1e-12
gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s... 68 2e-11
gi|71164894 trinucleotide repeat containing 4 [Homo sapiens] 67 4e-11
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 65 1e-10
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 65 1e-10
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 65 1e-10
gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo s... 65 2e-10
>gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens]
Length = 524
Score = 1058 bits (2735), Expect = 0.0
Identities = 524/524 (100%), Positives = 524/524 (100%)
Query: 1 MTAEDSTAAMSSDSAAGSSAKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPP 60
MTAEDSTAAMSSDSAAGSSAKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPP
Sbjct: 1 MTAEDSTAAMSSDSAAGSSAKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPP 60
Query: 61 GWEGPHPQRGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCH 120
GWEGPHPQRGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCH
Sbjct: 61 GWEGPHPQRGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCH 120
Query: 121 KHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLD 180
KHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLD
Sbjct: 121 KHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLD 180
Query: 181 VIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDED 240
VIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDED
Sbjct: 181 VIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDED 240
Query: 241 VMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNN 300
VMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNN
Sbjct: 241 VMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNN 300
Query: 301 LNGTELEGSCLEVTLAKPVDKEQYSRYQKAARGGGAAEAAQQPSYVYSCDPYTLAYYGYP 360
LNGTELEGSCLEVTLAKPVDKEQYSRYQKAARGGGAAEAAQQPSYVYSCDPYTLAYYGYP
Sbjct: 301 LNGTELEGSCLEVTLAKPVDKEQYSRYQKAARGGGAAEAAQQPSYVYSCDPYTLAYYGYP 360
Query: 361 YNALIGPNRDYFVKVAIPAIGAQYSMFPAAPAPKMIEDGKIHTVEHMISPIAVQPDPASA 420
YNALIGPNRDYFVKVAIPAIGAQYSMFPAAPAPKMIEDGKIHTVEHMISPIAVQPDPASA
Sbjct: 361 YNALIGPNRDYFVKVAIPAIGAQYSMFPAAPAPKMIEDGKIHTVEHMISPIAVQPDPASA 420
Query: 421 AAAAAAAAAAAAAVIPTVSTPPPFQGRPITPVYTVAPNVQRIPTAGIYGASYVPFAAPAT 480
AAAAAAAAAAAAAVIPTVSTPPPFQGRPITPVYTVAPNVQRIPTAGIYGASYVPFAAPAT
Sbjct: 421 AAAAAAAAAAAAAVIPTVSTPPPFQGRPITPVYTVAPNVQRIPTAGIYGASYVPFAAPAT 480
Query: 481 ATIATLQKNAAAAAAMYGGYAGYIPQAFPAAAIQVPIPDVYQTY 524
ATIATLQKNAAAAAAMYGGYAGYIPQAFPAAAIQVPIPDVYQTY
Sbjct: 481 ATIATLQKNAAAAAAMYGGYAGYIPQAFPAAAIQVPIPDVYQTY 524
>gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens]
Length = 593
Score = 941 bits (2431), Expect = 0.0
Identities = 489/593 (82%), Positives = 499/593 (84%), Gaps = 69/593 (11%)
Query: 1 MTAEDSTAAMSSDSAAGSSAKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPP 60
MTAEDSTAAMSSDSAAGSSAKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPP
Sbjct: 1 MTAEDSTAAMSSDSAAGSSAKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPP 60
Query: 61 GWEGPHPQRGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCH 120
GWEGPHPQRGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCH
Sbjct: 61 GWEGPHPQRGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCH 120
Query: 121 KHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLD 180
KHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLD
Sbjct: 121 KHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLD 180
Query: 181 VIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDED 240
VIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDED
Sbjct: 181 VIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDED 240
Query: 241 VMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNN 300
VMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNN
Sbjct: 241 VMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNN 300
Query: 301 LNGTELEGSCLEVTLAKPVDKEQYSRYQKAARGGGAAEAAQQPSYVYSCDPYTLAYYGYP 360
LNGTELEGSCLEVTLAKPVDKEQYSRYQKAARGGGAAEAAQQPSYVYSCDPYTLAYYGYP
Sbjct: 301 LNGTELEGSCLEVTLAKPVDKEQYSRYQKAARGGGAAEAAQQPSYVYSCDPYTLAYYGYP 360
Query: 361 YNALIGPNRDYFVKVAIPAIGAQYSMFPAAPAPK---------------MIEDGKIHTVE 405
YNALIGPNRDYFVK + + AP P+ +GK E
Sbjct: 361 YNALIGPNRDYFVKAGSIRGRGRGAAGNRAPGPRGSYLGGYSAGRGIYSRYHEGKGKQQE 420
Query: 406 H-----------MISPIAVQPD--------------PASAA------------------- 421
++P+A++P PA+ A
Sbjct: 421 KGYELVPNLEIPTVNPVAIKPGTVAIPAIGAQYSMFPAAPAPKMIEDGKIHTVEHMISPI 480
Query: 422 ----------AAAAAAAAAAAAVIPTVSTPPPFQGRPITPVYTVAPNVQRIPTAGIYGAS 471
AAAAAAAAAAAAVIPTVSTPPPFQGRPITPVYTVAPNVQRIPTAGIYGAS
Sbjct: 481 AVQPDPASAAAAAAAAAAAAAAVIPTVSTPPPFQGRPITPVYTVAPNVQRIPTAGIYGAS 540
Query: 472 YVPFAAPATATIATLQKNAAAAAAMYGGYAGYIPQAFPAAAIQVPIPDVYQTY 524
YVPFAAPATATIATLQKNAAAAAAMYGGYAGYIPQAFPAAAIQVPIPDVYQTY
Sbjct: 541 YVPFAAPATATIATLQKNAAAAAAMYGGYAGYIPQAFPAAAIQVPIPDVYQTY 593
>gi|20357575 apobec-1 complementation factor isoform 2 [Homo
sapiens]
Length = 594
Score = 486 bits (1252), Expect = e-137
Identities = 238/347 (68%), Positives = 280/347 (80%), Gaps = 8/347 (2%)
Query: 18 SSAKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGK 77
S+ K +G++G EAAL AL++RTGYS+VQENGQRKYGGPPPGW+ P+RGCE+F+GK
Sbjct: 3 SNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGK 62
Query: 78 IPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELNNYEIR 137
+PRD++EDEL+P+ E +G+IYE+R+MMDF+G NRGYAFV + +K EAK A+++LNNYEIR
Sbjct: 63 LPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIR 122
Query: 138 PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFA 197
GRLLGVC SVDNCRLF+GGIPK KKREEIL E+ KVTEGV+DVIVY SAADK KNRGFA
Sbjct: 123 NGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFA 182
Query: 198 FVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIET 257
FVEYESHRAAAMARRKL+PGRIQLWGH IAVDWAEPE++VDED M +VKILYVRNLM+ T
Sbjct: 183 FVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLST 242
Query: 258 TEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317
+E+ I+K F PG VERVKKIRDYAFVHF++REDAV AM LNG L+GS +EVTLAK
Sbjct: 243 SEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAK 302
Query: 318 PVDKEQYSRYQKAARGGGAAEAAQQPSYVYSC----DPYTLAYYGYP 360
PVDK+ Y RY RG G Q Y YS DP T Y G P
Sbjct: 303 PVDKDSYVRY---TRGTGGRGTMLQGEYTYSLGQVYDP-TTTYLGAP 345
>gi|20357572 apobec-1 complementation factor isoform 1 [Homo
sapiens]
Length = 586
Score = 486 bits (1252), Expect = e-137
Identities = 238/347 (68%), Positives = 280/347 (80%), Gaps = 8/347 (2%)
Query: 18 SSAKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGK 77
S+ K +G++G EAAL AL++RTGYS+VQENGQRKYGGPPPGW+ P+RGCE+F+GK
Sbjct: 3 SNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGK 62
Query: 78 IPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELNNYEIR 137
+PRD++EDEL+P+ E +G+IYE+R+MMDF+G NRGYAFV + +K EAK A+++LNNYEIR
Sbjct: 63 LPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIR 122
Query: 138 PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFA 197
GRLLGVC SVDNCRLF+GGIPK KKREEIL E+ KVTEGV+DVIVY SAADK KNRGFA
Sbjct: 123 NGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFA 182
Query: 198 FVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIET 257
FVEYESHRAAAMARRKL+PGRIQLWGH IAVDWAEPE++VDED M +VKILYVRNLM+ T
Sbjct: 183 FVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLST 242
Query: 258 TEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317
+E+ I+K F PG VERVKKIRDYAFVHF++REDAV AM LNG L+GS +EVTLAK
Sbjct: 243 SEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAK 302
Query: 318 PVDKEQYSRYQKAARGGGAAEAAQQPSYVYSC----DPYTLAYYGYP 360
PVDK+ Y RY RG G Q Y YS DP T Y G P
Sbjct: 303 PVDKDSYVRY---TRGTGGRGTMLQGEYTYSLGQVYDP-TTTYLGAP 345
>gi|21450675 RNA binding motif protein 46 [Homo sapiens]
Length = 533
Score = 465 bits (1196), Expect = e-131
Identities = 222/295 (75%), Positives = 255/295 (86%)
Query: 28 GAPNEAALLALMERTGYSMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGKIPRDVYEDEL 87
G NEAALLALME+TGY+MVQENGQRK+GGPPPGWEGP P RGCEVFVGKIPRD+YEDEL
Sbjct: 18 GIQNEAALLALMEKTGYNMVQENGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDMYEDEL 77
Query: 88 VPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELNNYEIRPGRLLGVCCS 147
VPVFE G+IYE RLMM+F G+NRGYAFVMY K EA+ A+R LNNYEIRPG+ +GVC S
Sbjct: 78 VPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVS 137
Query: 148 VDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAA 207
+DNCRLFIG IPK KK+EEIL+E+ KVTEGV+DVIVY SA DK KNRGFAFVEYESHRAA
Sbjct: 138 LDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAA 197
Query: 208 AMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKSFG 267
AMARRKL+PG QLWGH I VDWA+PE +VDE+ M+ VK+LYVRNLMI TTE+TIK F
Sbjct: 198 AMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFN 257
Query: 268 QFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAKPVDKE 322
+F PG VERVKK+RDYAFVHF +REDAV AM+ +NG ++G+ +EVTLAKPV+KE
Sbjct: 258 KFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKE 312
>gi|20357578 apobec-1 complementation factor isoform 3 [Homo
sapiens]
Length = 594
Score = 455 bits (1170), Expect = e-128
Identities = 221/317 (69%), Positives = 257/317 (81%), Gaps = 8/317 (2%)
Query: 48 QENGQRKYGGPPPGWEGPHPQRGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFD 107
+ENGQRKYGGPPPGW+ P+RGCE+F+GK+PRD++EDEL+P+ E +G+IYE+R+MMDF+
Sbjct: 41 KENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFN 100
Query: 108 GKNRGYAFVMYCHKHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEI 167
G NRGYAFV + +K EAK A+++LNNYEIR GRLLGVC SVDNCRLF+GGIPK KKREEI
Sbjct: 101 GNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEI 160
Query: 168 LEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIA 227
L E+ KVTEGV+DVIVY SAADK KNRGFAFVEYESHRAAAMARRKL+PGRIQLWGH IA
Sbjct: 161 LSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIA 220
Query: 228 VDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRDYAFVH 287
VDWAEPE++VDED M +VKILYVRNLM+ T+E+ I+K F PG VERVKKIRDYAFVH
Sbjct: 221 VDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVH 280
Query: 288 FTSREDAVHAMNNLNGTELEGSCLEVTLAKPVDKEQYSRYQKAARGGGAAEAAQQPSYVY 347
F++REDAV AM LNG L+GS +EVTLAKPVDK+ Y RY RG G Q Y Y
Sbjct: 281 FSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRY---TRGTGGRGTMLQGEYTY 337
Query: 348 SC----DPYTLAYYGYP 360
S DP T Y G P
Sbjct: 338 SLGQVYDP-TTTYLGAP 353
>gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4
[Homo sapiens]
Length = 532
Score = 355 bits (910), Expect = 7e-98
Identities = 189/380 (49%), Positives = 247/380 (65%), Gaps = 33/380 (8%)
Query: 20 AKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPG--WEGPHPQRGCEVFVGK 77
+KV E G P+EA + AL+ERTGY++ GQRKYGGPPP + G P G EVFVGK
Sbjct: 12 SKVQESTKG-PDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGK 70
Query: 78 IPRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHKHEAKRAVRELNNYEI 136
IPRD+YEDELVP+FE G I++LRLMMD G+NRGYAF+ +C K A+ AV+ ++YEI
Sbjct: 71 IPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEI 130
Query: 137 RPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGF 196
RPG+ LGVC SV N RLF+G IPK K +E ILEE +KVTEG++DVI+Y DK KNRGF
Sbjct: 131 RPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGF 190
Query: 197 AFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIE 256
F+EYE H++AA ARR+LM G++++WG+ + V+WA+P + D +VM VK+L+VRNL
Sbjct: 191 CFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATT 250
Query: 257 TTEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLA 316
TE+ ++KSF +F G +ERVKK++DYAFVHF R AV AM+ +NG E+EG +E+ LA
Sbjct: 251 VTEEILEKSFSEF--GKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLA 308
Query: 317 KPVDKEQYSR--------------------------YQKAARGGGAAEAAQQPSYVYSCD 350
KP DK++ R + RGGG P Y Y +
Sbjct: 309 KPPDKKRKERQAARQASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGYGYPPDY-YGYE 367
Query: 351 PYTLAYYGYPYNALIGPNRD 370
Y YYGY Y+ G D
Sbjct: 368 DYYDDYYGYDYHDYRGGYED 387
>gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2
[Homo sapiens]
Length = 633
Score = 355 bits (910), Expect = 7e-98
Identities = 189/380 (49%), Positives = 247/380 (65%), Gaps = 33/380 (8%)
Query: 20 AKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPG--WEGPHPQRGCEVFVGK 77
+KV E G P+EA + AL+ERTGY++ GQRKYGGPPP + G P G EVFVGK
Sbjct: 113 SKVQESTKG-PDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGK 171
Query: 78 IPRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHKHEAKRAVRELNNYEI 136
IPRD+YEDELVP+FE G I++LRLMMD G+NRGYAF+ +C K A+ AV+ ++YEI
Sbjct: 172 IPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEI 231
Query: 137 RPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGF 196
RPG+ LGVC SV N RLF+G IPK K +E ILEE +KVTEG++DVI+Y DK KNRGF
Sbjct: 232 RPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGF 291
Query: 197 AFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIE 256
F+EYE H++AA ARR+LM G++++WG+ + V+WA+P + D +VM VK+L+VRNL
Sbjct: 292 CFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATT 351
Query: 257 TTEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLA 316
TE+ ++KSF +F G +ERVKK++DYAFVHF R AV AM+ +NG E+EG +E+ LA
Sbjct: 352 VTEEILEKSFSEF--GKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLA 409
Query: 317 KPVDKEQYSR--------------------------YQKAARGGGAAEAAQQPSYVYSCD 350
KP DK++ R + RGGG P Y Y +
Sbjct: 410 KPPDKKRKERQAARQASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGYGYPPDY-YGYE 468
Query: 351 PYTLAYYGYPYNALIGPNRD 370
Y YYGY Y+ G D
Sbjct: 469 DYYDDYYGYDYHDYRGGYED 488
>gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3
[Homo sapiens]
Length = 535
Score = 349 bits (896), Expect = 3e-96
Identities = 189/383 (49%), Positives = 247/383 (64%), Gaps = 36/383 (9%)
Query: 20 AKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPG--WEGPHPQRGCEVFVGK 77
+KV E G P+EA + AL+ERTGY++ GQRKYGGPPP + G P G EVFVGK
Sbjct: 12 SKVQESTKG-PDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGK 70
Query: 78 IPRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHKHEAKRAVRELNNYEI 136
IPRD+YEDELVP+FE G I++LRLMMD G+NRGYAF+ +C K A+ AV+ ++YEI
Sbjct: 71 IPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEI 130
Query: 137 RPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVT---EGVLDVIVYASAADKMKN 193
RPG+ LGVC SV N RLF+G IPK K +E ILEE +KVT EG++DVI+Y DK KN
Sbjct: 131 RPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFSKVTGLTEGLVDVILYHQPDDKKKN 190
Query: 194 RGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNL 253
RGF F+EYE H++AA ARR+LM G++++WG+ + V+WA+P + D +VM VK+L+VRNL
Sbjct: 191 RGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNL 250
Query: 254 MIETTEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEV 313
TE+ ++KSF +F G +ERVKK++DYAFVHF R AV AM+ +NG E+EG +E+
Sbjct: 251 ATTVTEEILEKSFSEF--GKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEI 308
Query: 314 TLAKPVDKEQYSR--------------------------YQKAARGGGAAEAAQQPSYVY 347
LAKP DK++ R + RGGG P Y Y
Sbjct: 309 VLAKPPDKKRKERQAARQASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGYGYPPDY-Y 367
Query: 348 SCDPYTLAYYGYPYNALIGPNRD 370
+ Y YYGY Y+ G D
Sbjct: 368 GYEDYYDDYYGYDYHDYRGGYED 390
>gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1
[Homo sapiens]
Length = 636
Score = 349 bits (896), Expect = 3e-96
Identities = 189/383 (49%), Positives = 247/383 (64%), Gaps = 36/383 (9%)
Query: 20 AKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPG--WEGPHPQRGCEVFVGK 77
+KV E G P+EA + AL+ERTGY++ GQRKYGGPPP + G P G EVFVGK
Sbjct: 113 SKVQESTKG-PDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGK 171
Query: 78 IPRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHKHEAKRAVRELNNYEI 136
IPRD+YEDELVP+FE G I++LRLMMD G+NRGYAF+ +C K A+ AV+ ++YEI
Sbjct: 172 IPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEI 231
Query: 137 RPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVT---EGVLDVIVYASAADKMKN 193
RPG+ LGVC SV N RLF+G IPK K +E ILEE +KVT EG++DVI+Y DK KN
Sbjct: 232 RPGKHLGVCISVANNRLFVGSIPKNKTKENILEEFSKVTGLTEGLVDVILYHQPDDKKKN 291
Query: 194 RGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNL 253
RGF F+EYE H++AA ARR+LM G++++WG+ + V+WA+P + D +VM VK+L+VRNL
Sbjct: 292 RGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNL 351
Query: 254 MIETTEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEV 313
TE+ ++KSF +F G +ERVKK++DYAFVHF R AV AM+ +NG E+EG +E+
Sbjct: 352 ATTVTEEILEKSFSEF--GKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEI 409
Query: 314 TLAKPVDKEQYSR--------------------------YQKAARGGGAAEAAQQPSYVY 347
LAKP DK++ R + RGGG P Y Y
Sbjct: 410 VLAKPPDKKRKERQAARQASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGYGYPPDY-Y 468
Query: 348 SCDPYTLAYYGYPYNALIGPNRD 370
+ Y YYGY Y+ G D
Sbjct: 469 GYEDYYDDYYGYDYHDYRGGYED 491
>gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 6 [Homo sapiens]
Length = 562
Score = 340 bits (873), Expect = 1e-93
Identities = 187/390 (47%), Positives = 246/390 (63%), Gaps = 31/390 (7%)
Query: 21 KVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPG--WEGPHPQRGCEVFVGKI 78
KV + G P+EA + AL+ERTGY++ GQRKYGGPPP + G P G E+FVGKI
Sbjct: 111 KVADSSKG-PDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKI 169
Query: 79 PRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHKHEAKRAVRELNNYEIR 137
PRD++EDELVP+FE G I++LRLMMD G NRGYAFV +C K A+ AV+ NN+EIR
Sbjct: 170 PRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIR 229
Query: 138 PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFA 197
G+ +GVC SV N RLF+G IPK K +E+ILEE +KVTEG+ DVI+Y DK KNRGF
Sbjct: 230 SGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFC 289
Query: 198 FVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIET 257
F+EYE H+ AA ARR+LM G++++WG+ V+WA+P D D +VM VK+L+VRNL
Sbjct: 290 FLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTV 349
Query: 258 TEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317
TE+ ++K+F QF G +ERVKK++DYAF+HF R+ AV AM +NG +LEG +E+ AK
Sbjct: 350 TEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAK 407
Query: 318 PVD---KEQYSRYQKA---------------------ARGGGAAEAAQQPSYVYSCDPYT 353
P D KE+ ++ Q A RG G P Y + Y
Sbjct: 408 PPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDY- 466
Query: 354 LAYYGYPYNALIGPNRDYFVKVAIPAIGAQ 383
YYGY Y+ G D + +GA+
Sbjct: 467 YDYYGYDYHNYRGGYEDPYYGYEDFQVGAR 496
>gi|228008396 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 2 [Homo sapiens]
Length = 464
Score = 340 bits (873), Expect = 1e-93
Identities = 187/390 (47%), Positives = 246/390 (63%), Gaps = 31/390 (7%)
Query: 21 KVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPG--WEGPHPQRGCEVFVGKI 78
KV + G P+EA + AL+ERTGY++ GQRKYGGPPP + G P G E+FVGKI
Sbjct: 13 KVADSSKG-PDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKI 71
Query: 79 PRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHKHEAKRAVRELNNYEIR 137
PRD++EDELVP+FE G I++LRLMMD G NRGYAFV +C K A+ AV+ NN+EIR
Sbjct: 72 PRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIR 131
Query: 138 PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFA 197
G+ +GVC SV N RLF+G IPK K +E+ILEE +KVTEG+ DVI+Y DK KNRGF
Sbjct: 132 SGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFC 191
Query: 198 FVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIET 257
F+EYE H+ AA ARR+LM G++++WG+ V+WA+P D D +VM VK+L+VRNL
Sbjct: 192 FLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTV 251
Query: 258 TEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317
TE+ ++K+F QF G +ERVKK++DYAF+HF R+ AV AM +NG +LEG +E+ AK
Sbjct: 252 TEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAK 309
Query: 318 PVD---KEQYSRYQKA---------------------ARGGGAAEAAQQPSYVYSCDPYT 353
P D KE+ ++ Q A RG G P Y + Y
Sbjct: 310 PPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDY- 368
Query: 354 LAYYGYPYNALIGPNRDYFVKVAIPAIGAQ 383
YYGY Y+ G D + +GA+
Sbjct: 369 YDYYGYDYHNYRGGYEDPYYGYEDFQVGAR 398
>gi|228008293 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 5 [Homo sapiens]
Length = 561
Score = 340 bits (873), Expect = 1e-93
Identities = 187/390 (47%), Positives = 246/390 (63%), Gaps = 31/390 (7%)
Query: 21 KVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPG--WEGPHPQRGCEVFVGKI 78
KV + G P+EA + AL+ERTGY++ GQRKYGGPPP + G P G E+FVGKI
Sbjct: 111 KVADSSKG-PDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKI 169
Query: 79 PRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHKHEAKRAVRELNNYEIR 137
PRD++EDELVP+FE G I++LRLMMD G NRGYAFV +C K A+ AV+ NN+EIR
Sbjct: 170 PRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIR 229
Query: 138 PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFA 197
G+ +GVC SV N RLF+G IPK K +E+ILEE +KVTEG+ DVI+Y DK KNRGF
Sbjct: 230 SGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFC 289
Query: 198 FVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIET 257
F+EYE H+ AA ARR+LM G++++WG+ V+WA+P D D +VM VK+L+VRNL
Sbjct: 290 FLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTV 349
Query: 258 TEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317
TE+ ++K+F QF G +ERVKK++DYAF+HF R+ AV AM +NG +LEG +E+ AK
Sbjct: 350 TEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAK 407
Query: 318 PVD---KEQYSRYQKA---------------------ARGGGAAEAAQQPSYVYSCDPYT 353
P D KE+ ++ Q A RG G P Y + Y
Sbjct: 408 PPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDY- 466
Query: 354 LAYYGYPYNALIGPNRDYFVKVAIPAIGAQ 383
YYGY Y+ G D + +GA+
Sbjct: 467 YDYYGYDYHNYRGGYEDPYYGYEDFQVGAR 496
>gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 1 [Homo sapiens]
Length = 623
Score = 340 bits (873), Expect = 1e-93
Identities = 187/390 (47%), Positives = 246/390 (63%), Gaps = 31/390 (7%)
Query: 21 KVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPG--WEGPHPQRGCEVFVGKI 78
KV + G P+EA + AL+ERTGY++ GQRKYGGPPP + G P G E+FVGKI
Sbjct: 111 KVADSSKG-PDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKI 169
Query: 79 PRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHKHEAKRAVRELNNYEIR 137
PRD++EDELVP+FE G I++LRLMMD G NRGYAFV +C K A+ AV+ NN+EIR
Sbjct: 170 PRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIR 229
Query: 138 PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFA 197
G+ +GVC SV N RLF+G IPK K +E+ILEE +KVTEG+ DVI+Y DK KNRGF
Sbjct: 230 SGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFC 289
Query: 198 FVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIET 257
F+EYE H+ AA ARR+LM G++++WG+ V+WA+P D D +VM VK+L+VRNL
Sbjct: 290 FLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTV 349
Query: 258 TEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317
TE+ ++K+F QF G +ERVKK++DYAF+HF R+ AV AM +NG +LEG +E+ AK
Sbjct: 350 TEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAK 407
Query: 318 PVD---KEQYSRYQKA---------------------ARGGGAAEAAQQPSYVYSCDPYT 353
P D KE+ ++ Q A RG G P Y + Y
Sbjct: 408 PPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDY- 466
Query: 354 LAYYGYPYNALIGPNRDYFVKVAIPAIGAQ 383
YYGY Y+ G D + +GA+
Sbjct: 467 YDYYGYDYHNYRGGYEDPYYGYEDFQVGAR 496
>gi|228008398 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 3 [Homo sapiens]
Length = 527
Score = 288 bits (736), Expect = 1e-77
Identities = 171/390 (43%), Positives = 221/390 (56%), Gaps = 66/390 (16%)
Query: 21 KVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPG--WEGPHPQRGCEVFVGKI 78
KV + G P+EA + AL+ERTGY++ GQRKYGGPPP + G P G E+FVGKI
Sbjct: 111 KVADSSKG-PDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKI 169
Query: 79 PRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHKHEAKRAVRELNNYEIR 137
PRD++EDELVP+FE G I++LRLMMD G NRGYAFV +C K A+ AV+ NN+EIR
Sbjct: 170 PRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIR 229
Query: 138 PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFA 197
G+ +GVC SV N RLF+G IPK K +E+ILEE +KVTEG+ DVI+Y DK KNRGF
Sbjct: 230 SGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFC 289
Query: 198 FVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIET 257
F+EYE H+ AA VK+L+VRNL
Sbjct: 290 FLEYEDHKTAAQ-----------------------------------VKVLFVRNLANTV 314
Query: 258 TEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317
TE+ ++K+F QF G +ERVKK++DYAF+HF R+ AV AM +NG +LEG +E+ AK
Sbjct: 315 TEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAK 372
Query: 318 PVD---KEQYSRYQKA---------------------ARGGGAAEAAQQPSYVYSCDPYT 353
P D KE+ ++ Q A RG G P Y + Y
Sbjct: 373 PPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDY- 431
Query: 354 LAYYGYPYNALIGPNRDYFVKVAIPAIGAQ 383
YYGY Y+ G D + +GA+
Sbjct: 432 YDYYGYDYHNYRGGYEDPYYGYEDFQVGAR 461
>gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 4 [Homo sapiens]
Length = 588
Score = 288 bits (736), Expect = 1e-77
Identities = 171/390 (43%), Positives = 221/390 (56%), Gaps = 66/390 (16%)
Query: 21 KVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPG--WEGPHPQRGCEVFVGKI 78
KV + G P+EA + AL+ERTGY++ GQRKYGGPPP + G P G E+FVGKI
Sbjct: 111 KVADSSKG-PDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKI 169
Query: 79 PRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHKHEAKRAVRELNNYEIR 137
PRD++EDELVP+FE G I++LRLMMD G NRGYAFV +C K A+ AV+ NN+EIR
Sbjct: 170 PRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIR 229
Query: 138 PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFA 197
G+ +GVC SV N RLF+G IPK K +E+ILEE +KVTEG+ DVI+Y DK KNRGF
Sbjct: 230 SGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFC 289
Query: 198 FVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIET 257
F+EYE H+ AA VK+L+VRNL
Sbjct: 290 FLEYEDHKTAAQ-----------------------------------VKVLFVRNLANTV 314
Query: 258 TEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317
TE+ ++K+F QF G +ERVKK++DYAF+HF R+ AV AM +NG +LEG +E+ AK
Sbjct: 315 TEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAK 372
Query: 318 PVD---KEQYSRYQKA---------------------ARGGGAAEAAQQPSYVYSCDPYT 353
P D KE+ ++ Q A RG G P Y + Y
Sbjct: 373 PPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDY- 431
Query: 354 LAYYGYPYNALIGPNRDYFVKVAIPAIGAQ 383
YYGY Y+ G D + +GA+
Sbjct: 432 YDYYGYDYHNYRGGYEDPYYGYEDFQVGAR 461
>gi|34740339 dead end homolog 1 [Homo sapiens]
Length = 353
Score = 184 bits (466), Expect = 2e-46
Identities = 89/205 (43%), Positives = 130/205 (63%), Gaps = 2/205 (0%)
Query: 31 NEAALLALMERTGYSMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGKIPRDVYEDELVPV 90
N+AAL A + TG +VQ NGQRKYGGPPPGW G P G EVF+G++P+DVYE +L+P+
Sbjct: 18 NKAALEAWVRETGIRLVQVNGQRKYGGPPPGWVGSPPPAGSEVFIGRLPQDVYEHQLIPL 77
Query: 91 FEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELNNYEIRPGRLLGVCCSVDN 150
F+ VGR+YE RLMM F G NRG+A+ Y + A+ A+ L+N+ +RP L VC S +
Sbjct: 78 FQRVGRLYEFRLMMTFSGLNRGFAYARYSSRRGAQAAIATLHNHPLRPSCPLLVCRSTEK 137
Query: 151 CRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMA 210
C L + G+P R +L + + G+ + + S A +++ SHRAAAMA
Sbjct: 138 CELSVDGLPPNLTRSALLLALQPLGPGLQEARLLPSPGPAPGQ--IALLKFSSHRAAAMA 195
Query: 211 RRKLMPGRIQLWGHQIAVDWAEPEI 235
++ L+ G+ L G Q+AV+W +P++
Sbjct: 196 KKALVEGQSHLCGEQVAVEWLKPDL 220
>gi|93277122 RNA binding motif protein 4 [Homo sapiens]
Length = 364
Score = 82.8 bits (203), Expect = 7e-16
Identities = 96/350 (27%), Positives = 141/350 (40%), Gaps = 65/350 (18%)
Query: 152 RLFIGGIPKMKKREEI---LEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAA 208
+LFIG +P+ +EI E+ KV E D +KN GF +E ++ AA
Sbjct: 3 KLFIGNLPREATEQEIRSLFEQYGKVLE-----------CDIIKNYGFVHIEDKT--AAE 49
Query: 209 MARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKSFGQ 268
A R L H + ++ ++ +T L+V N+ T ++ F +
Sbjct: 50 DAIRNL---------HHYKLHGVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEE 100
Query: 269 FNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAKP---------- 318
+ P V ++DYAFVH EDAV A+ L+ TE +G + V L+
Sbjct: 101 YGP--VIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGD 158
Query: 319 ------VDKE-QYSRYQKAARGGGAAEAAQQPSYVYSC--DPYTLA-----YYGYPYNAL 364
KE +S+ R G A+ +Q + Y PYT++ YY Y AL
Sbjct: 159 QSGCYRCGKEGHWSKECPIDRSGRVADLTEQYNEQYGAVRTPYTMSYGDSLYYNNAYGAL 218
Query: 365 ------IGPNRDYFVKVAIPAIGAQYSMFPAAPAPKMIEDGKI-HTVEHMISPIAVQPDP 417
R Y A A Y+ + P++ H + P P
Sbjct: 219 DAYYKRCRAARSYEAVAAAAASVYNYAEQTLSQLPQVQNTAMASHLTSTSLDPYDRHLLP 278
Query: 418 ASAAAAAAAAAAAAAAVIPTVSTPPPFQGRPITPV-YTVAPNVQRIPTAG 466
S AAA AAAAAAAAA + ST + GR +P+ AP +PT G
Sbjct: 279 TSGAAATAAAAAAAAAAVTAAST--SYYGRDRSPLRRATAP----VPTVG 322
Score = 40.0 bits (92), Expect = 0.005
Identities = 40/154 (25%), Positives = 68/154 (44%), Gaps = 36/154 (23%)
Query: 72 EVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVREL 131
++F+G +PR+ E E+ +FE G++ E ++ + Y FV K A+ A+R L
Sbjct: 3 KLFIGNLPREATEQEIRSLFEQYGKVLECDII-------KNYGFVHIEDKTAAEDAIRNL 55
Query: 132 NNYEIRPGRLLGVCCSVD--------NCRLFIGGIPKMKKREEI---LEEIAKVTEGVLD 180
++Y +L GV +V+ + +L +G I +E+ EE V E D
Sbjct: 56 HHY-----KLHGVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIE--CD 108
Query: 181 VIVYASAADKMKNRGFAFVEYESHRAAAMARRKL 214
++ + +AFV E A A R L
Sbjct: 109 IV-----------KDYAFVHMERAEDAVEAIRGL 131
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 79.0 bits (193), Expect = 1e-14
Identities = 75/286 (26%), Positives = 128/286 (44%), Gaps = 58/286 (20%)
Query: 73 VFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELN 132
VF+ + + + L F A G+I ++M D G ++GYAFV + ++ A RA+ E+N
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEMN 158
Query: 133 NYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKRE-EILEEIAKVT-------------EGV 178
G+LL C++F+G K RE E+ + ++ T E +
Sbjct: 159 ------GKLL------KGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERL 206
Query: 179 LDVI--------VYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDW 230
DV V K++GF FV ++SH AA A + M GR + G I V
Sbjct: 207 KDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEE-MNGR-DINGQLIFVGR 264
Query: 231 AEPEIDVDEDVMETVK-------------ILYVRNLMIETTEDTIKKSFGQFNPGCVERV 277
A+ +++ ++ + + LY++NL ++ ++ F F G + RV
Sbjct: 265 AQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRNEFSSF--GSISRV 322
Query: 278 KKIRD------YAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317
K +++ + + F+S EDA AM +NG L L + LA+
Sbjct: 323 KVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQ 368
Score = 32.3 bits (72), Expect = 1.1
Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 6/72 (8%)
Query: 248 LYVRNLMIETTEDTIKKSFGQFNPGCVERV------KKIRDYAFVHFTSREDAVHAMNNL 301
LYV +L + TED + + F P R+ ++ YA+V+F DA A++ +
Sbjct: 12 LYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTM 71
Query: 302 NGTELEGSCLEV 313
N ++G + +
Sbjct: 72 NFDIIKGKSIRL 83
>gi|13899354 RNA binding motif protein 4B [Homo sapiens]
Length = 359
Score = 77.8 bits (190), Expect = 2e-14
Identities = 101/373 (27%), Positives = 151/373 (40%), Gaps = 79/373 (21%)
Query: 152 RLFIGGIPKMKKREEI---LEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAA 208
+LFIG +P+ +EI E+ KV E D +KN GF +E ++ AA
Sbjct: 3 KLFIGNLPREATEQEIRSLFEQYGKVLE-----------CDIIKNYGFVHIEDKT--AAE 49
Query: 209 MARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKSFGQ 268
A R L H + ++ ++ + L+V N+ T ++ F +
Sbjct: 50 DAIRNL---------HHYKLHGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEE 100
Query: 269 FNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLA------KPVDKE 322
+ P V ++DYAFVH EDAV A+ L+ TE +G + V L+ P +
Sbjct: 101 YGP--VIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGD 158
Query: 323 QYSRYQKAARG-----------GGAAEAAQQPSYVYSC--DPYTLA-----YYGYPYNAL 364
Q Y+ G G A+ +Q + Y PYT+ YY Y AL
Sbjct: 159 QSGCYRCGKEGHWSKECPVDRTGRVADFTEQYNEQYGAVRTPYTMGYGESMYYNDAYGAL 218
Query: 365 IGPNRDYFVKVAIPAIGAQYSMFPAAPAPKMIEDGKIH-------TVEHMISPIAVQPD- 416
DY+ + + + A + AA A E H TV ++ +V P
Sbjct: 219 -----DYYKRYRVRSYEA-VAAAAAASAYNYAEQTMSHLPQVQSTTVTSHLNSTSVDPYD 272
Query: 417 ----PASAAAAAAAAAAAAAAVIPTVSTPPPFQGRPITPVYTVAPNVQRIPTAGIYGASY 472
P S AAA +AA AAAAA T + GR +P+ A +PT G G Y
Sbjct: 273 RHLLPNSGAAATSAAMAAAAA------TTSSYYGRDRSPLRRAA---AMLPTVG-EGYGY 322
Query: 473 VPFAAPATATIAT 485
P + + A+ AT
Sbjct: 323 GPESELSQASAAT 335
Score = 40.4 bits (93), Expect = 0.004
Identities = 40/154 (25%), Positives = 68/154 (44%), Gaps = 36/154 (23%)
Query: 72 EVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVREL 131
++F+G +PR+ E E+ +FE G++ E ++ + Y FV K A+ A+R L
Sbjct: 3 KLFIGNLPREATEQEIRSLFEQYGKVLECDII-------KNYGFVHIEDKTAAEDAIRNL 55
Query: 132 NNYEIRPGRLLGVCCSVD--------NCRLFIGGIPKMKKREEI---LEEIAKVTEGVLD 180
++Y +L GV +V+ + +L +G I +E+ EE V E D
Sbjct: 56 HHY-----KLHGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIE--CD 108
Query: 181 VIVYASAADKMKNRGFAFVEYESHRAAAMARRKL 214
++ + +AFV E A A R L
Sbjct: 109 IV-----------KDYAFVHMERAEDAVEAIRGL 131
>gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo
sapiens]
Length = 485
Score = 75.5 bits (184), Expect = 1e-13
Identities = 57/183 (31%), Positives = 86/183 (46%), Gaps = 27/183 (14%)
Query: 59 PPGWEGPHPQRG----------CEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMD-FD 107
P G GP P G ++FVG+IPR + E +L P+FE GRIYEL ++ D +
Sbjct: 23 PVGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYT 82
Query: 108 GKNRGYAFVMYCHKHEAKRAVRELNNYEIRPGRLLGVCCSVDNC--------RLFIGGIP 159
G ++G AF+ YC + A +A L+ + PG + + +LF+G +
Sbjct: 83 GMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLN 142
Query: 160 KMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKL----- 214
K + E++L GV+D D ++G AFV++ SH A A L
Sbjct: 143 KQQSEEDVLRLFQPF--GVIDECTVLRGPDG-SSKGCAFVKFSSHTEAQAAIHALHGSQT 199
Query: 215 MPG 217
MPG
Sbjct: 200 MPG 202
Score = 40.0 bits (92), Expect = 0.005
Identities = 22/80 (27%), Positives = 43/80 (53%), Gaps = 4/80 (5%)
Query: 63 EGPHPQRGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHK 121
EGP GC +F+ +P++ + EL +F G I ++ MD +++ + FV + +
Sbjct: 395 EGPE---GCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDNP 451
Query: 122 HEAKRAVRELNNYEIRPGRL 141
A+ A++ +N ++I RL
Sbjct: 452 ASAQAAIQAMNGFQIGMKRL 471
Score = 31.6 bits (70), Expect = 1.9
Identities = 49/197 (24%), Positives = 87/197 (44%), Gaps = 35/197 (17%)
Query: 148 VDNCRLFIGGIPKM---KKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESH 204
+D +LF+G IP+ K + + E+ ++ E + Y ++G AF+ Y +
Sbjct: 42 LDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGM-----HKGCAFLTYCAR 96
Query: 205 RAA-----AMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTE 259
+A A+ +K +PG + I V A+ E D + L+V L + +E
Sbjct: 97 DSAIKAQTALHEQKTLPGMAR----PIQVKPADSESRGGRD-----RKLFVGMLNKQQSE 147
Query: 260 DTIKKSFGQFNPGCVERVKKIRD-------YAFVHFTSREDAVHAMNNLNGTEL---EGS 309
+ + + F F G ++ +R AFV F+S +A A++ L+G++ S
Sbjct: 148 EDVLRLFQPF--GVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASS 205
Query: 310 CLEVTLAKPVDKEQYSR 326
L V A DKE+ R
Sbjct: 206 SLVVKFA-DTDKERTLR 221
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 73.2 bits (178), Expect = 6e-13
Identities = 105/443 (23%), Positives = 180/443 (40%), Gaps = 101/443 (22%)
Query: 73 VFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELN 132
+F+ + + + L F A G I +++ D +G ++GY FV + + A+RA+ ++N
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYGFVHFETQEAAERAIEKMN 159
Query: 133 NYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVL------------- 179
G LL ++ ++F+G K+RE L AK V
Sbjct: 160 ------GMLL------NDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERL 207
Query: 180 ---------DVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDW 230
+ V + K++GF FV +E H A A + M G+ +L G QI V
Sbjct: 208 KDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDE-MNGK-ELNGKQIYVGR 265
Query: 231 AEPEIDVDEDV------METVKI-------LYVRNLMIETTEDTIKKSFGQFNPGCVERV 277
A+ +++ ++ M+ +I LYV+NL ++ ++K F F +V
Sbjct: 266 AQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKV 325
Query: 278 K----KIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAKPVDKEQYSRYQKAARG 333
+ + + FV F+S E+A A+ +NG + L V LA+ ++ Q + +
Sbjct: 326 MMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQR 385
Query: 334 GGAAEAAQQPSYVYSCDPYTLAYYGYPYNALIGPNRDYFVKVAIPAIGAQYSMFPAA--- 390
+ A P +PY A P YF+ AIP + + +P +
Sbjct: 386 MASVRAVPNP----VINPYQPA-----------PPSGYFM-AAIPQTQNRAAYYPPSQIA 429
Query: 391 ---PAPKMIEDG-KIHTVEHM---ISPIAVQPD-----PASAAAAAAAA----------- 427
P+P+ G + H ++M I P A +P PAS+ +
Sbjct: 430 QLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQRVANTSTQT 489
Query: 428 -----AAAAAAVIPTVSTPPPFQ 445
AAAAAA P V T P ++
Sbjct: 490 MGPRPAAAAAAATPAVRTVPQYK 512
Score = 66.2 bits (160), Expect = 7e-11
Identities = 65/271 (23%), Positives = 122/271 (45%), Gaps = 31/271 (11%)
Query: 73 VFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDF-DGKNRGYAFVMYCHKHEAKRAVREL 131
++VG + DV E L F G I +R+ D ++ GYA+V + +A+RA+ +
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 132 NNYEIRPGRLLGVCCSVDNCRLFIGGIPKM--KKREEILEEIA--KVTEGVLDVIVYASA 187
N +++ G+ + + S + L G+ + K ++ ++ A +++
Sbjct: 73 N-FDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 188 ADKMKNRGFAFVEYESHRAAAMA----------RRKLMPGRIQLWGHQIAVDWAEPEIDV 237
D+ ++G+ FV +E+ AA A RK+ GR + E E ++
Sbjct: 132 CDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFK--------SRKEREAEL 183
Query: 238 DEDVMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVK-----KIRDYAFVHFTSRE 292
E + Y++N + ++ +K FG+F P +V K + + FV F E
Sbjct: 184 GARAKEFTNV-YIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHE 242
Query: 293 DAVHAMNNLNGTELEGSCLEVTLA-KPVDKE 322
DA A++ +NG EL G + V A K V+++
Sbjct: 243 DAQKAVDEMNGKELNGKQIYVGRAQKKVERQ 273
Score = 41.2 bits (95), Expect = 0.002
Identities = 19/73 (26%), Positives = 38/73 (52%)
Query: 64 GPHPQRGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHE 123
G + V++ D+ ++ L +F G +++M D GK++G+ FV + +
Sbjct: 184 GARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHED 243
Query: 124 AKRAVRELNNYEI 136
A++AV E+N E+
Sbjct: 244 AQKAVDEMNGKEL 256
Score = 36.6 bits (83), Expect = 0.058
Identities = 18/64 (28%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Query: 69 RGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAV 128
+G ++V + + ++ L F G I ++MM+ G+++G+ FV + EA +AV
Sbjct: 292 QGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMME-GGRSKGFGFVCFSSPEEATKAV 350
Query: 129 RELN 132
E+N
Sbjct: 351 TEMN 354
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 72.4 bits (176), Expect = 9e-13
Identities = 72/257 (28%), Positives = 122/257 (47%), Gaps = 26/257 (10%)
Query: 73 VFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDF-DGKNRGYAFVMYCHKHEAKRAVREL 131
++VG + DV E L F G I +R+ D ++ GYA++ + +A+RA+ +
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTM 72
Query: 132 NNYEIRPGRLLGVCCSVDNCRLFIGGIPKM--KKREEILEEIAKV----TEGVLDVIVYA 185
N +E+ G+ + + S + L G+ + K E+ ++ A T G +++
Sbjct: 73 N-FEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFG--NILSCK 129
Query: 186 SAADKMKNRGFAFVEYESHRAAAMA----RRKLMPGRIQLWGHQIAVDWAEPEIDVDEDV 241
A D+ +RGF FV +E+H AA A L+ R GH E E ++
Sbjct: 130 VACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGH--FKSRREREAELGARA 187
Query: 242 METVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRD-------YAFVHFTSREDA 294
+E I YV+NL ++ E ++ F QF G + VK +RD + FV+F E+A
Sbjct: 188 LEFTNI-YVKNLPVDVDEQGLQDLFSQF--GKMLSVKVMRDNSGHSRCFGFVNFEKHEEA 244
Query: 295 VHAMNNLNGTELEGSCL 311
A+ ++NG E+ G L
Sbjct: 245 QKAVVHMNGKEVSGRLL 261
Score = 50.8 bits (120), Expect = 3e-06
Identities = 101/478 (21%), Positives = 173/478 (36%), Gaps = 110/478 (23%)
Query: 73 VFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELN 132
+F+ + + L F G I ++ D G +RG+ FV + A++A+ +N
Sbjct: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHG-SRGFGFVHFETHEAAQQAINTMN 159
Query: 133 NYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILE----EIAKV----------TEGV 178
G LL ++ ++F+G ++RE L E + +G+
Sbjct: 160 ------GMLL------NDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGL 207
Query: 179 LDVIVYASAADKMK--------NRGFAFVEYESHRAAAMA----RRKLMPGRIQLWGHQI 226
D+ +K +R F FV +E H A A K + GR+ G
Sbjct: 208 QDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRAQ 267
Query: 227 AVDWAEPEIDVDEDVMETVKI-------LYVRNLMIETTEDTIKKSFGQFNPGCVERVKK 279
+ E+ + M+ ++ LYV+NL +D ++K F + G + K
Sbjct: 268 KRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSPY--GVITSAKV 325
Query: 280 IRD------YAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLA------KPVDKEQYSRY 327
+ + + FV F+S E+A A+ +NG + L V LA K + QY +
Sbjct: 326 MTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYMQR 385
Query: 328 QKAAR--GGGAAEAAQQPSYVY----SCDPYTLAYYGYPYNALIGPNRDYFVKVAIPAIG 381
R + QQPS + P AYYG GP
Sbjct: 386 LSTMRTLSNPLLGSFQQPSSYFLPAMPQPPAQAAYYG------CGP-------------- 425
Query: 382 AQYSMFPAAPAPKMIEDGKIHTVEHMISPIAVQPDPASAAAAAAAAAAAAAAVIP----- 436
+ P PAP+ + M+ P V P + ++ A+ +P
Sbjct: 426 ----VTPTQPAPRWTSQPPRPSCASMVRPPVVPRRPPAHISSVRQASTQVPRTVPHTQRV 481
Query: 437 ----TVSTPPP-----FQGRPITP--VYTVAPNVQRIPTAGIYGASYVPFAAPATATI 483
T +T P GRP+ P + A + R+ + ++P P TA++
Sbjct: 482 ANIGTQTTGPSGVGCCTPGRPLLPCKCSSAAHSTYRVQEPAV----HIPGQEPLTASM 535
Score = 35.8 bits (81), Expect = 0.098
Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 7/75 (9%)
Query: 69 RGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAV 128
+G ++V + + +D+L F G I ++M + G ++G+ FV + EA +AV
Sbjct: 292 QGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTE-GGHSKGFGFVCFSSPEEATKAV 350
Query: 129 RELNNYEIRPGRLLG 143
E+N GR++G
Sbjct: 351 TEMN------GRIVG 359
Score = 29.3 bits (64), Expect = 9.2
Identities = 19/72 (26%), Positives = 34/72 (47%), Gaps = 6/72 (8%)
Query: 248 LYVRNLMIETTEDTIKKSFGQFNPGCVERV------KKIRDYAFVHFTSREDAVHAMNNL 301
LYV +L + TE + + F P RV ++ YA+++F DA A++ +
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTM 72
Query: 302 NGTELEGSCLEV 313
N L+G + +
Sbjct: 73 NFEMLKGQPIRI 84
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 72.0 bits (175), Expect = 1e-12
Identities = 101/430 (23%), Positives = 168/430 (39%), Gaps = 80/430 (18%)
Query: 73 VFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELN 132
+FV + + + L A G I ++ D +G ++GY FV + A+RA++++N
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENG-SKGYGFVHFETHEAAERAIKKMN 159
Query: 133 NYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVL------------- 179
G LL + ++F+G K+RE L AK V
Sbjct: 160 ------GMLL------NGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERL 207
Query: 180 ---------DVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDW 230
+ V + K++GF FV +E H A A + M G+ +L G QI V
Sbjct: 208 KDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDE-MNGK-ELNGKQIYVGR 265
Query: 231 AEPEIDVDEDVMET-------------VKILYVRNLMIETTEDTIKKSFGQFNPGCVERV 277
A+ +++ ++ T V LYV+NL ++ ++K+F F +V
Sbjct: 266 AQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKV 325
Query: 278 K----KIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAKPVDKEQY---SRYQKA 330
+ + + FV F+S E+A A+ +NG + L V LA+ ++ Q + Y +
Sbjct: 326 MMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAYLTNEYMQR 385
Query: 331 ARGGGAAEAAQQP--SYVYSCDPYT---LAYYGYPYNALIGPNRDYFVKVAIPAIGAQYS 385
A + P Y + P T AYY A + P+ + + A P
Sbjct: 386 MASVRAVPNQRAPPSGYFMTAVPQTQNHAAYYPPSQIARLRPSPRWTAQGARP------- 438
Query: 386 MFPAAPAPKMIEDGKIHTVEHMISPIAVQ----------PDPASAAAAAAAAAAAAAAVI 435
P P I G + P + Q + ++ AAAAAAA
Sbjct: 439 -HPFQNKPSAIRPGAPRVPFSTMRPASSQVPRVMSTQRVANTSTQTVGPRPAAAAAAAAT 497
Query: 436 PTVSTPPPFQ 445
P V T P ++
Sbjct: 498 PAVRTVPRYK 507
Score = 71.2 bits (173), Expect = 2e-12
Identities = 66/265 (24%), Positives = 120/265 (45%), Gaps = 19/265 (7%)
Query: 73 VFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDF-DGKNRGYAFVMYCHKHEAKRAVREL 131
++VG + DV E L F G I +R+ D + YA+V + H +A+ A+ +
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTM 72
Query: 132 NNYEIRPGRLLGVCCSVDNCRLFIGGIPKM--KKREEILEEIA--KVTEGVLDVIVYASA 187
N +++ G+ + + S + L G+ + K ++ + A +++
Sbjct: 73 N-FDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVV 131
Query: 188 ADKMKNRGFAFVEYESHRAAAMARRK----LMPGRIQLWGHQIAVDWAEPEIDVDEDVME 243
D+ ++G+ FV +E+H AA A +K L+ GR G + E E+
Sbjct: 132 CDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAELGARAKEFP 191
Query: 244 TVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVK-----KIRDYAFVHFTSREDAVHAM 298
V Y++N + ++ +K FG+F P +V K + + FV F EDA A+
Sbjct: 192 NV---YIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAV 248
Query: 299 NNLNGTELEGSCLEVTLA-KPVDKE 322
+ +NG EL G + V A K V+++
Sbjct: 249 DEMNGKELNGKQIYVGRAQKKVERQ 273
>gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo
sapiens]
Length = 448
Score = 68.2 bits (165), Expect = 2e-11
Identities = 47/162 (29%), Positives = 80/162 (49%), Gaps = 22/162 (13%)
Query: 72 EVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHKHEAKRAVRE 130
++F+G+IPR++ E +L P+FE G+IYEL ++ D F G ++G AF+ YC + A +A
Sbjct: 55 KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114
Query: 131 LNNYEIRPGRLLGVCCSV-------DNCRLFIGGIPKMKKREEI---LEEIAKVTEGVLD 180
L+ + PG + ++ +LF+G + K + +++ E + E +
Sbjct: 115 LHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTI- 173
Query: 181 VIVYASAADKMKNRGFAFVEYESHRAAAMARRKL-----MPG 217
++G AFV+Y SH A A L MPG
Sbjct: 174 -----LRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPG 210
Score = 49.3 bits (116), Expect = 9e-06
Identities = 99/388 (25%), Positives = 146/388 (37%), Gaps = 58/388 (14%)
Query: 149 DNCRLFIGGIPKM---KKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHR 205
D +LFIG IP+ K + + EE K+ E + V M ++G AF+ Y
Sbjct: 52 DAIKLFIGQIPRNLDEKDLKPLFEEFGKIYE----LTVLKDRFTGM-HKGCAFLTYCERE 106
Query: 206 AA-----AMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTED 260
+A A+ +K +PG I V A+ E ++ + L+V L + +ED
Sbjct: 107 SALKAQSALHEQKTLPGM----NRPIQVKPADSESRGED------RKLFVGMLNKQQSED 156
Query: 261 TIKKSFGQFNPGCVERVKKIRD-------YAFVHFTSREDAVHAMNNLNGTEL---EGSC 310
+++ F F G +E +R AFV ++S +A A+N L+G++ S
Sbjct: 157 DVRRLFEAF--GNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSS 214
Query: 311 LEVTLAKPVDKEQYSRYQKAARGGGAAEAAQQPSYVYSCDPYTLAYYGYPYNALIGPNRD 370
L V A DKE+ R + G Q + P+ YG AL+
Sbjct: 215 LVVKFA-DTDKERTMRRMQQMAG-------QMGMFNPMAIPF--GAYGAYAQALMQQQAA 264
Query: 371 YFVKVAIPAIGAQYSMFPAAPAPKMIEDGKIHTVEHMISPIAVQPDPASAAAAAAAAAAA 430
VA + F AA +M +M A P S + A
Sbjct: 265 LMASVAQGGYLNPMAAFAAAQMQQM-------AALNMNGLAAAPMTPTSGGSTPPGITAP 317
Query: 431 AAAVIPTVSTPPPFQGRPITPVYTVAPNVQRIPTAGI--YGASYVPFAAPATATIATLQK 488
A IP+ F G P P P + + GI Y A A P A +Q+
Sbjct: 318 AVPSIPSPIGVNGFTGLP--PQANGQPAAEAVFANGIHPYPAQSPTAADPLQQAYAGVQQ 375
Query: 489 NAAAAAAMYGGYAGYIPQAFPAAAIQVP 516
A AA Y G I QAFP +P
Sbjct: 376 YAGPAA--YPAAYGQISQAFPQPPPMIP 401
>gi|71164894 trinucleotide repeat containing 4 [Homo sapiens]
Length = 465
Score = 67.0 bits (162), Expect = 4e-11
Identities = 47/157 (29%), Positives = 82/157 (52%), Gaps = 15/157 (9%)
Query: 72 EVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHKHEAKRAVRE 130
++FVG+IPR + E +L P+FE GRI+EL ++ D + G ++G AF+ YC + A +A
Sbjct: 8 KLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDSALKAQSA 67
Query: 131 LNNYEIRPGRLLGVCCSV-------DNCRLFIGGIPKMKKREEILEEIAKVTE--GVLDV 181
L+ + PG + ++ +LF+G M +++ E++ K+ E G +D
Sbjct: 68 LHEQKTLPGMNRPIQVKPADSESRGEDRKLFVG----MLGKQQTDEDVRKMFEPFGTIDE 123
Query: 182 IVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGR 218
D ++G AFV++++H A A L R
Sbjct: 124 CTVLRGPDG-TSKGCAFVKFQTHAEAQAAINTLHSSR 159
Score = 42.7 bits (99), Expect = 8e-04
Identities = 93/400 (23%), Positives = 146/400 (36%), Gaps = 70/400 (17%)
Query: 149 DNCRLFIGGIPKMKKREE---ILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHR 205
D +LF+G IP+ + ++ I E+ ++ E + Y ++G AF+ Y +
Sbjct: 5 DAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGL-----HKGCAFLTYCARD 59
Query: 206 AA-----AMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTED 260
+A A+ +K +PG I V A+ E ++ + L+V L + T++
Sbjct: 60 SALKAQSALHEQKTLPGM----NRPIQVKPADSESRGED------RKLFVGMLGKQQTDE 109
Query: 261 TIKKSFGQFNPGCVERVKKIRD-------YAFVHFTSREDAVHAMNNLNGTEL---EGSC 310
++K F F G ++ +R AFV F + +A A+N L+ + S
Sbjct: 110 DVRKMFEPF--GTIDECTVLRGPDGTSKGCAFVKFQTHAEAQAAINTLHSSRTLPGASSS 167
Query: 311 LEVTLAKPVDKEQYSRYQKAARGGGAAEAAQQPSYVYSCDPYTLAYYGYPYNALIGPNRD 370
L V A + R Q+ A G YS YT A AL+ +
Sbjct: 168 LVVKFADTEKERGLRRMQQVATQLGMFSPIALQFGAYSA--YTQALM-QQQAALVAAHSA 224
Query: 371 YFVKVAIPAIGAQYSMFPAAPAPKMIEDGKIHTVEHMISPIAVQPDPASAAAAAAAAAAA 430
Y +A A A +M I+ + +PI P+S + A AA
Sbjct: 225 YLSPMATMA------------AVQMQHMAAINANGLIATPIT----PSSGTSTPPAIAAT 268
Query: 431 AAAVIPTVSTPPPFQGRPITPVYTVAPNVQRIPTAGIYGASYVPFAA--------PATAT 482
+ IP + P P AP+ +Y P+ A P
Sbjct: 269 PVSAIPAALGVNGYSPVPTQPTGQPAPD-------ALYPNGVHPYPAQSPAAPVDPLQQA 321
Query: 483 IATLQKNAAAAAAMYGGYAGYIPQAFPAAAIQVPIPDVYQ 522
A +Q AA A Y A PQ PA Q P P Q
Sbjct: 322 YAGMQHYTAAYPAAYSLVAPAFPQP-PALVAQQPPPPPQQ 360
Score = 39.7 bits (91), Expect = 0.007
Identities = 19/80 (23%), Positives = 44/80 (55%), Gaps = 4/80 (5%)
Query: 63 EGPHPQRGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHK 121
EGP GC +F+ +P++ + E++ +F G + ++ +D +++ + FV + +
Sbjct: 375 EGPD---GCNIFIYHLPQEFTDSEILQMFVPFGHVISAKVFVDRATNQSKCFGFVSFDNP 431
Query: 122 HEAKRAVRELNNYEIRPGRL 141
A+ A++ +N ++I RL
Sbjct: 432 ASAQAAIQAMNGFQIGMKRL 451
Score = 38.9 bits (89), Expect = 0.012
Identities = 20/68 (29%), Positives = 38/68 (55%)
Query: 72 EVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVREL 131
++FVG + + ++++ +FE G I E ++ DG ++G AFV + EA+ A+ L
Sbjct: 96 KLFVGMLGKQQTDEDVRKMFEPFGTIDECTVLRGPDGTSKGCAFVKFQTHAEAQAAINTL 155
Query: 132 NNYEIRPG 139
++ PG
Sbjct: 156 HSSRTLPG 163
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 65.5 bits (158), Expect = 1e-10
Identities = 66/273 (24%), Positives = 124/273 (45%), Gaps = 35/273 (12%)
Query: 73 VFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDF-DGKNRGYAFVMYCHKHEAKRAVREL 131
++VG + DV E L F G + +R+ D ++ GYA+V + +A+RA+ +
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 132 NNYEIRPGRLLGVCCSVDNCRLFIGGIPKM--KKREEILEEIA--KVTEGVLDVIVYASA 187
N +++ G+ + + S + L G+ + K ++ ++ A +++
Sbjct: 73 N-FDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 188 ADKMKNRGFAFVEYESHRAAAMA----------RRKLMPGRIQLWGHQIAVDWAEPEIDV 237
D+ ++G+AFV +E+ AA A RK+ GR + E E ++
Sbjct: 132 CDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFK--------SRKEREAEL 183
Query: 238 DEDVMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRD-------YAFVHFTS 290
E + Y++N E ++++K+ F QF G VK +RD + FV +
Sbjct: 184 GAKAKEFTNV-YIKNFGEEVDDESLKELFSQF--GKTLSVKVMRDPNGKSKGFGFVSYEK 240
Query: 291 REDAVHAMNNLNGTELEGSCLEVTLA-KPVDKE 322
EDA A+ +NG E+ G + V A K V+++
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQ 273
Score = 62.8 bits (151), Expect = 8e-10
Identities = 106/438 (24%), Positives = 175/438 (39%), Gaps = 84/438 (19%)
Query: 73 VFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELN 132
VF+ + + + L F A G I +++ D +G ++GYAFV + + A +A+ ++N
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMN 159
Query: 133 NYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKRE------------------------EIL 168
G LL ++ ++F+G K+RE E L
Sbjct: 160 ------GMLL------NDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESL 207
Query: 169 EEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAV 228
+E+ L V V K K GF FV YE H A A + M G+ ++ G I V
Sbjct: 208 KELFSQFGKTLSVKVMRDPNGKSK--GFGFVSYEKHEDANKAVEE-MNGK-EISGKIIFV 263
Query: 229 DWAEPEIDVDEDV---METVKI----------LYVRNLMIETTEDTIKKSFGQFNPGCVE 275
A+ +++ ++ E +K LY++NL ++ ++K F F
Sbjct: 264 GRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSA 323
Query: 276 RVK----KIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAKPVDKEQ---YSRYQ 328
+V + + + FV F+S E+A A+ +NG + L V LA+ ++ + ++Y
Sbjct: 324 KVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYM 383
Query: 329 KAARGGGAAEAAQ-----QPS---YVYSCDPYTLA---YYGYPYNALIGPNRDY------ 371
+ G A A QP+ Y P YY A + PN +
Sbjct: 384 QRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRP 443
Query: 372 ----FVKVAIPAIGAQYSMFPAAPAPKM-IEDGKIHTVEHMISPIAVQP-DPASAAAAAA 425
+ AI G + ++ AP G T + + P AVQ P +A AAAA
Sbjct: 444 QGFQGMPSAIRQSGPRPTLRHLAPTGNAPASRGLPTTTQRVGVPTAVQNLAPRAAVAAAA 503
Query: 426 AAAAAAAAVIPTVSTPPP 443
A A +V +P P
Sbjct: 504 PRAVAPYKYASSVRSPHP 521
Score = 39.3 bits (90), Expect = 0.009
Identities = 20/75 (26%), Positives = 42/75 (56%), Gaps = 7/75 (9%)
Query: 69 RGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAV 128
+G +++ + + +++L F G I ++M++ DG+++G+ FV + EA +AV
Sbjct: 292 QGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLE-DGRSKGFGFVCFSSPEEATKAV 350
Query: 129 RELNNYEIRPGRLLG 143
E+N GR++G
Sbjct: 351 TEMN------GRIVG 359
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 65.5 bits (158), Expect = 1e-10
Identities = 66/273 (24%), Positives = 124/273 (45%), Gaps = 35/273 (12%)
Query: 73 VFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDF-DGKNRGYAFVMYCHKHEAKRAVREL 131
++VG + DV E L F G + +R+ D ++ GYA+V + +A+RA+ +
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 132 NNYEIRPGRLLGVCCSVDNCRLFIGGIPKM--KKREEILEEIA--KVTEGVLDVIVYASA 187
N +++ G+ + + S + L G+ + K ++ ++ A +++
Sbjct: 73 N-FDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 188 ADKMKNRGFAFVEYESHRAAAMA----------RRKLMPGRIQLWGHQIAVDWAEPEIDV 237
D+ ++G+AFV +E+ AA A RK+ GR + E E ++
Sbjct: 132 CDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFK--------SRKEREAEL 183
Query: 238 DEDVMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRD-------YAFVHFTS 290
E + Y++N E ++++K+ F QF G VK +RD + FV +
Sbjct: 184 GAKAKEFTNV-YIKNFGEEVDDESLKELFSQF--GKTLSVKVMRDPNGKSKGFGFVSYEK 240
Query: 291 REDAVHAMNNLNGTELEGSCLEVTLA-KPVDKE 322
EDA A+ +NG E+ G + V A K V+++
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQ 273
Score = 62.0 bits (149), Expect = 1e-09
Identities = 71/286 (24%), Positives = 122/286 (42%), Gaps = 58/286 (20%)
Query: 73 VFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELN 132
VF+ + + + L F A G I +++ D +G ++GYAFV + + A +A+ ++N
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMN 159
Query: 133 NYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKRE------------------------EIL 168
G LL ++ ++F+G K+RE E L
Sbjct: 160 ------GMLL------NDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESL 207
Query: 169 EEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAV 228
+E+ L V V K K GF FV YE H A A + M G+ ++ G I V
Sbjct: 208 KELFSQFGKTLSVKVMRDPNGKSK--GFGFVSYEKHEDANKAVEE-MNGK-EISGKIIFV 263
Query: 229 DWAEPEIDVDEDV---METVKI----------LYVRNLMIETTEDTIKKSFGQFNPGCVE 275
A+ +++ ++ E +K LY++NL ++ ++K F F
Sbjct: 264 GRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSA 323
Query: 276 RVK----KIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317
+V + + + FV F+S E+A A+ +NG + L V LA+
Sbjct: 324 KVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQ 369
Score = 39.3 bits (90), Expect = 0.009
Identities = 20/75 (26%), Positives = 42/75 (56%), Gaps = 7/75 (9%)
Query: 69 RGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAV 128
+G +++ + + +++L F G I ++M++ DG+++G+ FV + EA +AV
Sbjct: 292 QGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLE-DGRSKGFGFVCFSSPEEATKAV 350
Query: 129 RELNNYEIRPGRLLG 143
E+N GR++G
Sbjct: 351 TEMN------GRIVG 359
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 65.5 bits (158), Expect = 1e-10
Identities = 66/273 (24%), Positives = 124/273 (45%), Gaps = 35/273 (12%)
Query: 73 VFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDF-DGKNRGYAFVMYCHKHEAKRAVREL 131
++VG + DV E L F G + +R+ D ++ GYA+V + +A+RA+ +
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 132 NNYEIRPGRLLGVCCSVDNCRLFIGGIPKM--KKREEILEEIA--KVTEGVLDVIVYASA 187
N +++ G+ + + S + L G+ + K ++ ++ A +++
Sbjct: 73 N-FDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 188 ADKMKNRGFAFVEYESHRAAAMA----------RRKLMPGRIQLWGHQIAVDWAEPEIDV 237
D+ ++G+AFV +E+ AA A RK+ GR + E E ++
Sbjct: 132 CDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFK--------SRKEREAEL 183
Query: 238 DEDVMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRD-------YAFVHFTS 290
E + Y++N E ++++K+ F QF G VK +RD + FV +
Sbjct: 184 GAKAKEFTNV-YIKNFGEEVDDESLKELFSQF--GKTLSVKVMRDPNGKSKGFGFVSYEK 240
Query: 291 REDAVHAMNNLNGTELEGSCLEVTLA-KPVDKE 322
EDA A+ +NG E+ G + V A K V+++
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQ 273
Score = 62.0 bits (149), Expect = 1e-09
Identities = 71/286 (24%), Positives = 122/286 (42%), Gaps = 58/286 (20%)
Query: 73 VFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELN 132
VF+ + + + L F A G I +++ D +G ++GYAFV + + A +A+ ++N
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMN 159
Query: 133 NYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKRE------------------------EIL 168
G LL ++ ++F+G K+RE E L
Sbjct: 160 ------GMLL------NDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESL 207
Query: 169 EEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAV 228
+E+ L V V K K GF FV YE H A A + M G+ ++ G I V
Sbjct: 208 KELFSQFGKTLSVKVMRDPNGKSK--GFGFVSYEKHEDANKAVEE-MNGK-EISGKIIFV 263
Query: 229 DWAEPEIDVDEDV---METVKI----------LYVRNLMIETTEDTIKKSFGQFNPGCVE 275
A+ +++ ++ E +K LY++NL ++ ++K F F
Sbjct: 264 GRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSA 323
Query: 276 RVK----KIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317
+V + + + FV F+S E+A A+ +NG + L V LA+
Sbjct: 324 KVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQ 369
Score = 39.3 bits (90), Expect = 0.009
Identities = 20/75 (26%), Positives = 42/75 (56%), Gaps = 7/75 (9%)
Query: 69 RGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAV 128
+G +++ + + +++L F G I ++M++ DG+++G+ FV + EA +AV
Sbjct: 292 QGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLE-DGRSKGFGFVCFSSPEEATKAV 350
Query: 129 RELNNYEIRPGRLLG 143
E+N GR++G
Sbjct: 351 TEMN------GRIVG 359
>gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo
sapiens]
Length = 484
Score = 65.1 bits (157), Expect = 2e-10
Identities = 49/171 (28%), Positives = 80/171 (46%), Gaps = 31/171 (18%)
Query: 72 EVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMD-FDGKNRGYAFVMYCHKHEAKRAVRE 130
++F+G+IPR++ E +L P+FE G+IYEL ++ D F G ++G AF+ YC + A +A
Sbjct: 55 KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114
Query: 131 LNNYEIRPGRLL-------------GVCC---SVDNCRLFIGGIPKMKKREEI---LEEI 171
L+ + PG G C + +LF+G + K + +++ E
Sbjct: 115 LHEQKTLPGMNRPIQVKPADSESRGGSSCLRQPPSHRKLFVGMLNKQQSEDDVRRLFEAF 174
Query: 172 AKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKL-----MPG 217
+ E + ++G AFV+Y SH A A L MPG
Sbjct: 175 GNIEECTI------LRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPG 219
Score = 46.2 bits (108), Expect = 7e-05
Identities = 96/391 (24%), Positives = 148/391 (37%), Gaps = 56/391 (14%)
Query: 149 DNCRLFIGGIPKM---KKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHR 205
D +LFIG IP+ K + + EE K+ E + V M ++G AF+ Y
Sbjct: 52 DAIKLFIGQIPRNLDEKDLKPLFEEFGKIYE----LTVLKDRFTGM-HKGCAFLTYCERE 106
Query: 206 AA-----AMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVME---TVKILYVRNLMIET 257
+A A+ +K +PG I V A+ E + + + L+V L +
Sbjct: 107 SALKAQSALHEQKTLPGM----NRPIQVKPADSESRGGSSCLRQPPSHRKLFVGMLNKQQ 162
Query: 258 TEDTIKKSFGQFNPGCVERVKKIRD-------YAFVHFTSREDAVHAMNNLNGTEL---E 307
+ED +++ F F G +E +R AFV ++S +A A+N L+G++
Sbjct: 163 SEDDVRRLFEAF--GNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGA 220
Query: 308 GSCLEVTLAKPVDKEQYSRYQKAARGGGAAEAAQQPSYVYSCDPYTLAYYGYPYNALIGP 367
S L V A DKE+ R + Q + +P + + Y A
Sbjct: 221 SSSLVVKFA-DTDKERTMRRMQ-----------QMAGQMGMFNPMAIPFGA--YGAYAQA 266
Query: 368 NRDYFVKVAIPAIGAQYSMFPAAPAPKMIEDGKIHTVEHMISPIAVQPDPASAAAAAAAA 427
+ +A A G + A A +M + + +M A P S +
Sbjct: 267 MQQQAALMASVAQGGYLNPMAAFAAAQMQQMAAL----NMNGLAAAPMTPTSGGSTPPGI 322
Query: 428 AAAAAAVIPTVSTPPPFQGRPITPVYTVAPNVQRIPTAGI--YGASYVPFAAPATATIAT 485
A A IP+ F G P P P + + GI Y A A P A
Sbjct: 323 TAPAVPSIPSPIGVNGFTGLP--PQANGQPAAEAVFANGIHPYPAQSPTAADPLQQAYAG 380
Query: 486 LQKNAAAAAAMYGGYAGYIPQAFPAAAIQVP 516
+Q+ A AA Y G I QAFP +P
Sbjct: 381 VQQYAGPAA--YPAAYGQISQAFPQPPPMIP 409
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,287,328
Number of Sequences: 37866
Number of extensions: 1069239
Number of successful extensions: 9507
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 255
Number of HSP's successfully gapped in prelim test: 248
Number of HSP's that attempted gapping in prelim test: 6317
Number of HSP's gapped (non-prelim): 1825
length of query: 524
length of database: 18,247,518
effective HSP length: 107
effective length of query: 417
effective length of database: 14,195,856
effective search space: 5919671952
effective search space used: 5919671952
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.