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Search of human proteins with 148806874
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148806874 hypothetical protein LOC54754 [Homo sapiens]
(756 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148806874 hypothetical protein LOC54754 [Homo sapiens] 1558 0.0
gi|169191513 PREDICTED: hypothetical protein isoform 1 [Homo sap... 1287 0.0
gi|150170710 hypothetical protein LOC728118 [Homo sapiens] 1283 0.0
gi|239744140 PREDICTED: hypothetical protein [Homo sapiens] 1282 0.0
gi|113865921 hypothetical protein LOC441457 [Homo sapiens] 973 0.0
gi|57528101 hypothetical protein LOC728130 [Homo sapiens] 890 0.0
gi|239744142 PREDICTED: hypothetical protein isoform 1 [Homo sap... 887 0.0
gi|50233787 nuclear protein in testis [Homo sapiens] 478 e-135
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 61 3e-09
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 59 1e-08
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 59 2e-08
gi|9945318 MAX binding protein [Homo sapiens] 59 2e-08
gi|150170670 piccolo isoform 2 [Homo sapiens] 57 5e-08
gi|150378539 piccolo isoform 1 [Homo sapiens] 57 5e-08
gi|153792074 proline rich 12 [Homo sapiens] 57 8e-08
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 56 1e-07
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 55 3e-07
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 54 4e-07
gi|56549694 enabled homolog isoform a [Homo sapiens] 54 7e-07
gi|39930375 enabled homolog isoform b [Homo sapiens] 54 7e-07
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 54 7e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 52 2e-06
gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo ... 52 3e-06
gi|239747993 PREDICTED: hypothetical protein XP_002346504 [Homo ... 52 3e-06
gi|239741891 PREDICTED: hypothetical protein XP_002342316 [Homo ... 52 3e-06
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 51 3e-06
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 51 3e-06
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 51 5e-06
gi|110349719 titin isoform N2-A [Homo sapiens] 50 6e-06
gi|56118221 amyloid beta (A4) precursor protein-binding, family ... 50 8e-06
>gi|148806874 hypothetical protein LOC54754 [Homo sapiens]
Length = 756
Score = 1558 bits (4034), Expect = 0.0
Identities = 756/756 (100%), Positives = 756/756 (100%)
Query: 1 MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFP 60
MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFP
Sbjct: 1 MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFP 60
Query: 61 STPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVM 120
STPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVM
Sbjct: 61 STPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVM 120
Query: 121 CPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGNARPWPQ 180
CPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGNARPWPQ
Sbjct: 121 CPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGNARPWPQ 180
Query: 181 GAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPV 240
GAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPV
Sbjct: 181 GAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPV 240
Query: 241 LRSLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMK 300
LRSLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMK
Sbjct: 241 LRSLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMK 300
Query: 301 GPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPP 360
GPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPP
Sbjct: 301 GPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPP 360
Query: 361 PRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQR 420
PRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQR
Sbjct: 361 PRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQR 420
Query: 421 EKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLA 480
EKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLA
Sbjct: 421 EKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLA 480
Query: 481 LSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPSEFAAGQEAAREVPD 540
LSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPSEFAAGQEAAREVPD
Sbjct: 481 LSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPSEFAAGQEAAREVPD 540
Query: 541 PQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDHR 600
PQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDHR
Sbjct: 541 PQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDHR 600
Query: 601 PTCPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQSPVP 660
PTCPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQSPVP
Sbjct: 601 PTCPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQSPVP 660
Query: 661 SSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKKRPLFGSPSPAEKTPHPGPGLRV 720
SSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKKRPLFGSPSPAEKTPHPGPGLRV
Sbjct: 661 SSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKKRPLFGSPSPAEKTPHPGPGLRV 720
Query: 721 SGEQSLAWGLGGPSQSQKRKGDPLASRRKKKRHCSQ 756
SGEQSLAWGLGGPSQSQKRKGDPLASRRKKKRHCSQ
Sbjct: 721 SGEQSLAWGLGGPSQSQKRKGDPLASRRKKKRHCSQ 756
>gi|169191513 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 878
Score = 1287 bits (3331), Expect = 0.0
Identities = 635/757 (83%), Positives = 671/757 (88%), Gaps = 2/757 (0%)
Query: 1 MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFP 60
MASNGAYPVLGPGVT NPGTSLSVFTALPF TPAPGPAH P LVTA PP GPLVLS FP
Sbjct: 123 MASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFP 182
Query: 61 STPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVM 120
STPLV QDG GPSGAGASNVFVQMRTEVGPVK QAQTL+LTQAPLVWQAPG LCGGV+
Sbjct: 183 STPLVTEQDGCGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVV 242
Query: 121 CPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPP-AAQVAPIVSPGNARPWP 179
CPPPLLLAAAP VPV +AQVVGGTQACEGGWS GLPLPPPPP AAQ+ PIVS GNA PWP
Sbjct: 243 CPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWP 302
Query: 180 QGAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 239
QGAHGE SLA SQAKA PDDSC P+SVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP
Sbjct: 303 QGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 362
Query: 240 VLRSLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 299
VLRSLARRKPTMTLEEGLW+AMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM
Sbjct: 363 VLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 422
Query: 300 KGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLP 359
KGPQ LPPPA PRLEPRGPPAPEVVKQPVYLPSK GPKAPTACLPPPRPQRP TKA P
Sbjct: 423 KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPV-TKARRP 481
Query: 360 PPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQ 419
PPRP R AET A LPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLG G TGEPE Q
Sbjct: 482 PPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQ 541
Query: 420 REKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFL 479
RE+GKV+QPQEED DPGLLSYIDKLCSQ+DFVTKVEAVIHP+FLEELLSPDPQMDFL
Sbjct: 542 REEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFL 601
Query: 480 ALSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPSEFAAGQEAAREVP 539
ALSQ+LEQEEGLTLAQLVEKRL LKEK RAAP GTARLDSS S+FAAGQ A R+VP
Sbjct: 602 ALSQDLEQEEGLTLAQLVEKRLPPLKEKQHARAAPSRGTARLDSSSSKFAAGQGAERDVP 661
Query: 540 DPQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDH 599
DPQQ V +ET PPQ A+D QG+GR TGMARSED VLLGCQDSP L+A PTSPPQDH
Sbjct: 662 DPQQGVGMETCPPQMTARDSQGRGRAHTGMARSEDSVVLLGCQDSPGLRAAWPTSPPQDH 721
Query: 600 RPTCPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQSPV 659
RPTCPG+GTKDAL LPG SPV+ESHGLA+GSSEE ELP + +++GS H+L PW L QSPV
Sbjct: 722 RPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSPV 781
Query: 660 PSSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKKRPLFGSPSPAEKTPHPGPGLR 719
P+SGLLSP GPQG QSPSA++RGL+ +PSPA+K+KKRPLFGS SPAEKTP+PGPGLR
Sbjct: 782 PASGLLSPEKWGPQGTHQSPSAERRGLNLAPSPANKAKKRPLFGSLSPAEKTPYPGPGLR 841
Query: 720 VSGEQSLAWGLGGPSQSQKRKGDPLASRRKKKRHCSQ 756
VSGEQSL WGLGGPSQSQKRKGDPL SR++KK+HCSQ
Sbjct: 842 VSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQHCSQ 878
>gi|150170710 hypothetical protein LOC728118 [Homo sapiens]
Length = 878
Score = 1283 bits (3321), Expect = 0.0
Identities = 633/757 (83%), Positives = 669/757 (88%), Gaps = 2/757 (0%)
Query: 1 MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFP 60
MASNGAYP LGPGVT NPGTSLSVFTALPF TPAPGPAH P LVTA PP GPLVLS P
Sbjct: 123 MASNGAYPALGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTLP 182
Query: 61 STPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVM 120
STPLV QDG GPSGAGASNVFVQMRTEVGPVK QAQTL+LTQAPLVWQAPG LCGGV+
Sbjct: 183 STPLVTEQDGCGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVV 242
Query: 121 CPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPP-AAQVAPIVSPGNARPWP 179
CPPPLLLAAAP VPV +AQVVGGTQACEGGWS GLPLPPPPP AAQ+ PIVS GNA PWP
Sbjct: 243 CPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWP 302
Query: 180 QGAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 239
QGAHGEGSLA SQAKA PDDSC P+SVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP
Sbjct: 303 QGAHGEGSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 362
Query: 240 VLRSLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 299
VLRSLARRKPTMTLEEGLW+AMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM
Sbjct: 363 VLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 422
Query: 300 KGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLP 359
KGPQ LPPPA PRLEPRGPPAPEVVKQPVYLPSK GPKAPTACLPPPRPQRP TKA P
Sbjct: 423 KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPV-TKARRP 481
Query: 360 PPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQ 419
PPRP R AET A LPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLG G TGEPE Q
Sbjct: 482 PPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQ 541
Query: 420 REKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFL 479
RE+G+V+QPQEED DPGLLSY DKLCSQ+DFVTKVEAVIHP+FLEELLSPDPQMDFL
Sbjct: 542 REEGEVKQPQEEDWTPPDPGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFL 601
Query: 480 ALSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPSEFAAGQEAAREVP 539
ALSQELEQEEGLTLAQLVEKRLL LKEK RAAP GTARLDSS S+FAAGQ A R+VP
Sbjct: 602 ALSQELEQEEGLTLAQLVEKRLLPLKEKQHARAAPSRGTARLDSSSSKFAAGQGAERDVP 661
Query: 540 DPQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDH 599
PQQ V +ET PPQT A+D QG+GR TGMARS+D VLLGCQDSP L+A RPTSPPQDH
Sbjct: 662 VPQQGVGMETCPPQTTARDSQGRGRAHTGMARSKDSVVLLGCQDSPGLRAARPTSPPQDH 721
Query: 600 RPTCPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQSPV 659
RPTCPG+GTKDAL LPG SPV+ESHGLA+GSSEE ELP + +++GS H+L PW L QSPV
Sbjct: 722 RPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSPV 781
Query: 660 PSSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKKRPLFGSPSPAEKTPHPGPGLR 719
P+SGLLSP GPQG Q PSA++RGL+ +PSPA+K+KKRPLFGS SPAEKTPHPGPGLR
Sbjct: 782 PASGLLSPEKWGPQGTHQFPSAERRGLNLAPSPANKAKKRPLFGSLSPAEKTPHPGPGLR 841
Query: 720 VSGEQSLAWGLGGPSQSQKRKGDPLASRRKKKRHCSQ 756
VSGEQSL WGLGGPSQSQKRKGDPL SR++KK+ CSQ
Sbjct: 842 VSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQRCSQ 878
>gi|239744140 PREDICTED: hypothetical protein [Homo sapiens]
Length = 878
Score = 1282 bits (3317), Expect = 0.0
Identities = 632/757 (83%), Positives = 670/757 (88%), Gaps = 2/757 (0%)
Query: 1 MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFP 60
MASNGAYPVLGPGVT NPGTSLSVFTALPF TPAPGPAH P LVTA PP GPLVLS FP
Sbjct: 123 MASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFP 182
Query: 61 STPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVM 120
STPLV QDG PSGAGASNVFVQMRTEVGPVK QAQTL+LTQAPLVWQAPG LCGGV+
Sbjct: 183 STPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVV 242
Query: 121 CPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPP-AAQVAPIVSPGNARPWP 179
CPPPLLLAAAP VPV +AQVVGGTQACEGGWS GLPLPPPPP AAQ+ PIVS GNA PWP
Sbjct: 243 CPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWP 302
Query: 180 QGAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 239
QGAHGE SLA SQAKA PDDSC P+SVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP
Sbjct: 303 QGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 362
Query: 240 VLRSLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 299
VLRSLARRKPTMTLEEGLW+AMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM
Sbjct: 363 VLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 422
Query: 300 KGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLP 359
KGPQ LPPPA PRLEPRGPPAPEVVKQPVYLPSK GPKA TACLPPPRPQRP TKA P
Sbjct: 423 KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRP 481
Query: 360 PPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQ 419
PP+P R AET A LPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLG G TGEPE Q
Sbjct: 482 PPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQ 541
Query: 420 REKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFL 479
RE+GKV+QPQEED DPGLLSYIDKLCSQ+DFVTKVEAVIHP+FLEELLSPDPQMDFL
Sbjct: 542 REEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFL 601
Query: 480 ALSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPSEFAAGQEAAREVP 539
ALSQ+LEQEEGLTLAQLVEKRL LKEK RAAP GTARLDSS S+FAAGQ A R+VP
Sbjct: 602 ALSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSSSKFAAGQGAERDVP 661
Query: 540 DPQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDH 599
DPQ+ V +ET PPQT A+D QG+GR TGMARSED VLLGCQDSP L+A RPTSPPQDH
Sbjct: 662 DPQEGVGMETCPPQTTARDSQGRGRAHTGMARSEDSVVLLGCQDSPGLRAARPTSPPQDH 721
Query: 600 RPTCPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQSPV 659
RPTCPG+GTKDAL LPG SPV+ESHGLA+GSSEE ELP + +++GS H+L PW L QSPV
Sbjct: 722 RPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSPV 781
Query: 660 PSSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKKRPLFGSPSPAEKTPHPGPGLR 719
P+SGLLSP GPQG QSPSA++RGL+ +PSPA+K+KK+PLFGS SPAEKTPH GPGLR
Sbjct: 782 PASGLLSPEKWGPQGTHQSPSAERRGLNLAPSPANKAKKQPLFGSLSPAEKTPHRGPGLR 841
Query: 720 VSGEQSLAWGLGGPSQSQKRKGDPLASRRKKKRHCSQ 756
VSGEQSL WGLGGPSQSQKRKGDPL SR++KK+HCSQ
Sbjct: 842 VSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQHCSQ 878
>gi|113865921 hypothetical protein LOC441457 [Homo sapiens]
Length = 492
Score = 973 bits (2516), Expect = 0.0
Identities = 473/495 (95%), Positives = 476/495 (96%), Gaps = 15/495 (3%)
Query: 1 MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFP 60
MASNGAYPVLGPGVTVNPGTSLSVFTALPFATP+PGP HRPPLVTAVVPPAGPLVLSAFP
Sbjct: 1 MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPSPGPTHRPPLVTAVVPPAGPLVLSAFP 60
Query: 61 STPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVM 120
STPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVM
Sbjct: 61 STPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVM 120
Query: 121 CPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGNARPWPQ 180
CPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGNA PWPQ
Sbjct: 121 CPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGNAGPWPQ 180
Query: 181 GAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPV 240
GAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPV
Sbjct: 181 GAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPV 240
Query: 241 LRSLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMK 300
LRSLARRKPTMTLEEGLW+AMREWQHTSNFDRMIFYEMA KFLEFEAEEEMQIQKSQWMK
Sbjct: 241 LRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAAKFLEFEAEEEMQIQKSQWMK 300
Query: 301 GPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPP 360
GPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPP
Sbjct: 301 GPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPP 360
Query: 361 PRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQR 420
PR P RPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQR
Sbjct: 361 PR---------------PPRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQR 405
Query: 421 EKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLA 480
EKGKVEQPQEEDG+TSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLA
Sbjct: 406 EKGKVEQPQEEDGMTSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLA 465
Query: 481 LSQELEQEEGLTLAQ 495
LSQELEQEEGLTLAQ
Sbjct: 466 LSQELEQEEGLTLAQ 480
>gi|57528101 hypothetical protein LOC728130 [Homo sapiens]
Length = 557
Score = 890 bits (2300), Expect = 0.0
Identities = 438/496 (88%), Positives = 449/496 (90%), Gaps = 2/496 (0%)
Query: 1 MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFP 60
MASNGAYP LGPGVT NPGTSLSVFTALPF TPAPGPAH P LVTA PP GPLVLS FP
Sbjct: 51 MASNGAYPALGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSNFP 110
Query: 61 STPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVM 120
STPLV QDG GPSGAGASNVFVQMRTEVGPVK QAQTL+LTQ PLVWQAPG LCGGV+
Sbjct: 111 STPLVTEQDGCGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQTPLVWQAPGALCGGVV 170
Query: 121 CPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPP-AAQVAPIVSPGNARPWP 179
CPPPLLLAAAP VPV +AQVVGGTQACEGGWS GLPLPPPPP AAQ+ PIVS GNA PWP
Sbjct: 171 CPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWP 230
Query: 180 QGAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 239
QGAHGEGSLA SQAKA PDDSC P+SVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP
Sbjct: 231 QGAHGEGSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 290
Query: 240 VLRSLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 299
VLRSLARRKPTMTLEEGLW+AMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM
Sbjct: 291 VLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 350
Query: 300 KGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLP 359
KGPQ LPPPA PRLEPRGPPAPEVVKQPVYLPSK GPKAPTACLPPPRPQRP TKA P
Sbjct: 351 KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPV-TKARRP 409
Query: 360 PPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQ 419
PPRP R AET A LPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLG G TGEPE Q
Sbjct: 410 PPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQ 469
Query: 420 REKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFL 479
RE+G+V+QPQEED DPGLLSY DKLCSQ+DFVTKVEAVIHP+FLEELLSPDPQMDFL
Sbjct: 470 REEGEVKQPQEEDWTPPDPGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFL 529
Query: 480 ALSQELEQEEGLTLAQ 495
ALSQELEQEEGLTLAQ
Sbjct: 530 ALSQELEQEEGLTLAQ 545
>gi|239744142 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 629
Score = 887 bits (2292), Expect = 0.0
Identities = 437/496 (88%), Positives = 449/496 (90%), Gaps = 2/496 (0%)
Query: 1 MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFP 60
MASNGAYPVLGPGVT NPGTSLSVFTALPF TPAPGPAH P LVTA PP GPLVLS FP
Sbjct: 123 MASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFP 182
Query: 61 STPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVM 120
STPLV QDG PSGAGASNVFVQMRTEVGPVK QAQTL+LTQAPLVWQAPG LCGGV+
Sbjct: 183 STPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVV 242
Query: 121 CPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPP-AAQVAPIVSPGNARPWP 179
CPPPLLLAAAP VPV +AQVVGGTQACEGGWS GLPLPPPPP AAQ+ PIVS GNA PWP
Sbjct: 243 CPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWP 302
Query: 180 QGAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 239
QGAHGE SLA SQAKA PDDSC P+SVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP
Sbjct: 303 QGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 362
Query: 240 VLRSLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 299
VLRSLARRKPTMTLEEGLW+AMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM
Sbjct: 363 VLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 422
Query: 300 KGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLP 359
KGPQ LPPPA PRLEPRGPPAPEVVKQPVYLPSK GPKA TACLPPPRPQRP TKA P
Sbjct: 423 KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRP 481
Query: 360 PPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQ 419
PP+P R AET A LPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLG G TGEPE Q
Sbjct: 482 PPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQ 541
Query: 420 REKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFL 479
RE+GKV+QPQEED DPGLLSYIDKLCSQ+DFVTKVEAVIHP+FLEELLSPDPQMDFL
Sbjct: 542 REEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFL 601
Query: 480 ALSQELEQEEGLTLAQ 495
ALSQ+LEQEEGLTLAQ
Sbjct: 602 ALSQDLEQEEGLTLAQ 617
>gi|50233787 nuclear protein in testis [Homo sapiens]
Length = 1132
Score = 478 bits (1231), Expect = e-135
Identities = 283/534 (52%), Positives = 344/534 (64%), Gaps = 46/534 (8%)
Query: 1 MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPP-------LVTAVVPPAGP 53
MAS+GA + GP +++ P +LS ALPF P P PP ++ +V P P
Sbjct: 1 MASDGASALPGPDMSMKPSAALSPSPALPFLPPTSDPPDHPPREPPPQPIMPSVFSPDNP 60
Query: 54 LVLSAFPSTPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPG 113
L+LSAFPS+ LV G G SGAGA V V+++TE G +P Q Q ILTQ L APG
Sbjct: 61 LMLSAFPSSLLVTGDGGPCLSGAGAGKVIVKVKTEGGSAEPSQTQNFILTQTALNSTAPG 120
Query: 114 TLCGGVMCPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPG 173
T CGG+ P P + A+ + ++ VG +Q EG GLP PPPP AQ+ PIV
Sbjct: 121 TPCGGLEGPAPPFVTASNVKTILPSKAVGVSQ--EG--PPGLPPQPPPPVAQLVPIVPLE 176
Query: 174 NARPWPQGAHGEGSLAPSQAKARPDDSCK-PKSVYENFRLWQHYKPLARRHLPQSPDTEA 232
A P P G GEG + +K D K K VYENFR WQ YK LARRHL QSPDTEA
Sbjct: 177 KAWPGPHGTTGEGGPVATLSKPSLGDRSKISKDVYENFRQWQRYKALARRHLSQSPDTEA 236
Query: 233 LSCFLIPVLRSLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQ 292
LSCFLIPVLRSLAR KPTMTLEEGL A++EW+HTSNFDRMIFYEMAE+F+EFEA EEMQ
Sbjct: 237 LSCFLIPVLRSLARLKPTMTLEEGLPLAVQEWEHTSNFDRMIFYEMAERFMEFEA-EEMQ 295
Query: 293 IQKSQWMKGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPA 352
IQ +Q M G Q L P P +L+P GP A EV +QPVY+P K K
Sbjct: 296 IQNTQLMNGSQGLSPATPLKLDPLGPLASEVCQQPVYIPKKAASK--------------- 340
Query: 353 ETKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGD 412
T+A P R QR A QRP + P+EIPPE V+EYVDIME L+G+H
Sbjct: 341 -TRA---PRRRQRKA-----------QRPPAPEAPKEIPPEAVKEYVDIMEWLVGTHLA- 384
Query: 413 TGEPEGQREKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSP 472
TGE +G++E + Q QEE+G+ DPGLLSYI++LCSQ+ FV+KVEAVIHP+FL +LLSP
Sbjct: 385 TGESDGKQE--EEGQQQEEEGMYPDPGLLSYINELCSQKVFVSKVEAVIHPQFLADLLSP 442
Query: 473 DPQMDFLALSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPS 526
+ Q D LAL +ELEQEEGLTLAQLV+KRL++L+E+ A P A+LDSSPS
Sbjct: 443 EKQRDPLALIEELEQEEGLTLAQLVQKRLMALEEEEDAEAPPSFSGAQLDSSPS 496
Score = 115 bits (288), Expect = 2e-25
Identities = 82/226 (36%), Positives = 114/226 (50%), Gaps = 17/226 (7%)
Query: 542 QQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDHRP 601
Q RVS +T P + DPQG+GRV +++ ++ A L Q+S + TS Q
Sbjct: 913 QLRVSEDTCPLNVHSYDPQGEGRVDPDLSKPKNLAPLQESQESYTTGTPKATSSHQGLGS 972
Query: 602 TCPGLGTKDALGLPGESPVKESHGLA-----------KGSSEETELPGMVYVVGSHHRLR 650
T P GT++A+ +P E+ V ++H A + E+ EL Y++ S L
Sbjct: 973 TLPRRGTRNAI-VPRETSVSKTHRSADRAKGKEKKKKEAEEEDEELSNFAYLLASKLSLS 1031
Query: 651 PWRLSQSPVPSSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKKRPLFGSPSPAEK 710
P SP +SG G+G Q A A +G S P P +KS KR L G P+P EK
Sbjct: 1032 PREHPLSPHHASG-----GQGSQRASHLLPAGAKGPSKLPYPVAKSGKRALAGGPAPTEK 1086
Query: 711 TPHPGPGLRVSGEQSLAWGLGGPSQSQKRKGDPLASRRKKKRHCSQ 756
TPH G L V E+ LA G+ PSQ +KR+ D + R+KKR SQ
Sbjct: 1087 TPHSGAQLGVPREKPLALGVVRPSQPRKRRCDSFVTGRRKKRRRSQ 1132
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 61.2 bits (147), Expect = 3e-09
Identities = 118/486 (24%), Positives = 175/486 (36%), Gaps = 51/486 (10%)
Query: 279 AEKFLEF-EAEEEMQIQKSQWM-KGPQSLPPPAPPRL-----EPRGPPA--PEVVKQPV- 328
A F +F E+ + ++ +W+ + P LPP +L E PPA PE+V Q V
Sbjct: 1752 ASDFKDFQESSPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPASPPEMVGQRVP 1811
Query: 329 YLPSKDGPKAPTACLP-----PPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAE 383
P ++ P +P P P A+ +P RP PA + PP P +
Sbjct: 1812 SAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESH 1871
Query: 384 TKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQREKGKVEQPQEEDGITSDPGLLSY 443
T P V ++E G P G ++ K E +EE+G P S+
Sbjct: 1872 TPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLG-KDYRKAEGEREEEGRAEAPDKSSH 1930
Query: 444 IDKLCSQEDFVTKVEAVIHPRFLE-ELLSPDPQMDFLALSQELEQEEGLTLAQLVEKRLL 502
K+ +K A P E E P P D E A + E+ +L
Sbjct: 1931 SSKVPE----ASKSHATTEPEQTEPEQREPTPYPD----------ERSFQYADIYEQMML 1976
Query: 503 SLKEKGCGRAAPRHGTARLDSSPSEFAAGQEAAREVPDPQQRVSVETSPPQTAAQDPQGQ 562
+ C P G A P + + AA ++ +S SP + P
Sbjct: 1977 TGLGPACPTREPPLGAA--GDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPTFS 2034
Query: 563 GRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDHRPTCPGLGTKDALGLPGESPVKE 622
G P + S AV P +P P+ P G + SP +
Sbjct: 2035 YAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPK 2094
Query: 623 SHGLAK--GSSEETELPGMVYVVGSHHRLRPWRLSQSPVPSSGLL--SPGGRGPQGALQS 678
G + S+ ++EL R +P + +QSP P + SP A S
Sbjct: 2095 ESGRSHWDDSTSDSELE-------KGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVS 2147
Query: 679 PSAQKRGLSPSPS---PASK---SKKRPLFGS-PSPAEKTPHPGPGLRVSGEQSLAWGLG 731
P PS PAS S +P PSPAE P L SG+++LA G
Sbjct: 2148 PPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPG 2207
Query: 732 GPSQSQ 737
P++++
Sbjct: 2208 PPTRTR 2213
Score = 36.6 bits (83), Expect = 0.089
Identities = 107/424 (25%), Positives = 138/424 (32%), Gaps = 102/424 (24%)
Query: 33 PAPGPAHRPPLVTAVVPPAGPLVLSAFPSTP-----LVAGQDGRGPS---------GAGA 78
P PGP+ P L VPP P +LS PS P L D R PS
Sbjct: 2047 PEPGPSMEPSLTPPAVPPRAP-ILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDST 2105
Query: 79 SNVFVQMRTEVGPVKPPQAQT---LILTQAPLVWQAPGTLCGGVMCPPPLLLAAAPGVPV 135
S+ ++ P K Q+ + I +P +W P T PPL P P
Sbjct: 2106 SDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLW--PET---EAHVSPPLDSHLGPARPS 2160
Query: 136 TSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGNARPWPQGAHGEGSLAPSQAKA 195
A G+S P PP P SP R P GSLA S +A
Sbjct: 2161 LD------FPASAFGFSSLQPAPPQLP--------SPAEPRSAPC-----GSLAFSGDRA 2201
Query: 196 RPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEE 255
P + L P LPQ P + P+L +L R + L E
Sbjct: 2202 LALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGA---PLLSNLP-RPASPALSE 2257
Query: 256 GLWQAMREWQHTSNFDRMIFYEMAEKF---LEFEAEEEMQIQ-------KSQWMKGPQSL 305
G +S + +AE+F LE +E ++ S W P S
Sbjct: 2258 G---------SSSEATTPVISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSP 2308
Query: 306 PPPAPPRLEPRGPPAPEV---------------------VKQPVYLPSKD-GPKAPTACL 343
PPA L+ PAP + P +PS+D PT
Sbjct: 2309 APPA--SLDLALAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETS 2366
Query: 344 PPPRPQRPA----ETKAHLP-------PPRPQRPAETNAHLPPPRPQRPA--ETKVPEEI 390
P P PA E A P P +R + + L P +P PA P
Sbjct: 2367 PNPPGPAPAKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPEQPVCPAGGSGGPPSSA 2426
Query: 391 PPEV 394
PEV
Sbjct: 2427 SPEV 2430
Score = 33.5 bits (75), Expect = 0.75
Identities = 67/299 (22%), Positives = 98/299 (32%), Gaps = 43/299 (14%)
Query: 294 QKSQWMKG------PQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKA---PTACLP 344
++ W +G P +L P P G P PS P+ P C
Sbjct: 2389 ERGAWPEGAERSSRPDTLLSPEQPVCPAGGSGGP---------PSSASPEVEAGPQGCAT 2439
Query: 345 PPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEE 404
PRP R + + L PP P P+ + L + P + +E
Sbjct: 2440 EPRPHRGELSPSFLNPPLP--PSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDE 2497
Query: 405 LLGSHPGDTGEPEGQREKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPR 464
+ D+G Q + + +E IT++ L S D D V HPR
Sbjct: 2498 TPPTSASDSG--SSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPR 2555
Query: 465 FLEE---LLSPDPQ----------MDFLALSQELEQEEGLTLAQLVEKRLLSLKEKGCGR 511
+ L PDP+ D LS E + E L + V+ R + + G+
Sbjct: 2556 PGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGR---VGRRAPGK 2612
Query: 512 AAPRHGTARLD-----SSPSEFAAGQEAAREVPDPQQRVSVETSPPQTAAQDPQGQGRV 565
A P RLD S A+R P P+ S T + P +G V
Sbjct: 2613 AKPASPARRLDLRGKRSPTPGKGPADRASRAPPRPRSTTSQVTPAEEKDGHSPMSKGLV 2671
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 59.3 bits (142), Expect = 1e-08
Identities = 49/138 (35%), Positives = 52/138 (37%), Gaps = 18/138 (13%)
Query: 307 PPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPP------ 360
PPAPPR PRG PA P P+ P AP A P R R A A PP
Sbjct: 108 PPAPPRA-PRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQ 166
Query: 361 --PRPQRPAETNAHLPPPRPQRP---AETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGE 415
PR QR A A PPP P P A P PP V E L P
Sbjct: 167 PGPRAQRAAPLAA--PPPAPAAPPAVAPPAGPRRAPPPAVA----AREPPLPPPPQPPAP 220
Query: 416 PEGQREKGKVEQPQEEDG 433
P+ Q+ QP E G
Sbjct: 221 PQQQQPPPPQPQPPPEGG 238
Score = 43.1 bits (100), Expect = 0.001
Identities = 38/136 (27%), Positives = 54/136 (39%), Gaps = 24/136 (17%)
Query: 306 PPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRP------AETKAHLP 359
P P P + PR A + P P AP A PP P+R A P
Sbjct: 160 PSPGPAQPGPRAQRAAPLAAPP------PAPAAPPAVAPPAGPRRAPPPAVAAREPPLPP 213
Query: 360 PPRPQRPAETNAHLPPPRPQRPAE---TKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEP 416
PP+P P + PPP+PQ P E + P ++E V + G +G
Sbjct: 214 PPQPPAPPQ-QQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYL--------GGSGGA 264
Query: 417 EGQREKGKVEQPQEED 432
G+ +G+V+ EE+
Sbjct: 265 GGRLTRGRVQGLLEEE 280
Score = 40.4 bits (93), Expect = 0.006
Identities = 39/153 (25%), Positives = 47/153 (30%), Gaps = 30/153 (19%)
Query: 29 PFATPAPGPAHRPPLVTAVVPPAGPLVLSAFPSTPLVAGQDGRGPSGAGASNVFVQMRTE 88
P PA A PP A PP P+ +A P A P G + +
Sbjct: 115 PRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPA--------Q 166
Query: 89 VGPVKPPQAQTLILTQAPLVWQAPGTLCGGVMCPPPLLLAAAPGVPVTSAQVVGGTQACE 148
GP A AP A G PPP + A P +P
Sbjct: 167 PGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPP------------ 214
Query: 149 GGWSHGLPLPPPPPAAQVAPIVSPGNARPWPQG 181
P PP PP Q P P +P P+G
Sbjct: 215 -------PQPPAPPQQQQPP---PPQPQPPPEG 237
Score = 37.4 bits (85), Expect = 0.052
Identities = 22/53 (41%), Positives = 25/53 (47%), Gaps = 11/53 (20%)
Query: 301 GPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAE 353
GP+ PPPA EP PP P QP P + P PPP+PQ P E
Sbjct: 195 GPRRAPPPAVAAREPPLPPPP----QPPAPPQQQQP-------PPPQPQPPPE 236
Score = 30.8 bits (68), Expect = 4.9
Identities = 22/63 (34%), Positives = 24/63 (38%), Gaps = 15/63 (23%)
Query: 156 PLPPPPPA--AQVAPI-------------VSPGNARPWPQGAHGEGSLAPSQAKARPDDS 200
P PPPPPA A AP SPG A+P P+ AP A A P
Sbjct: 131 PAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAV 190
Query: 201 CKP 203
P
Sbjct: 191 APP 193
Score = 30.0 bits (66), Expect = 8.3
Identities = 49/187 (26%), Positives = 66/187 (35%), Gaps = 28/187 (14%)
Query: 513 APRHGTARLDSSPSEFAAGQEAAREVPDPQ-QRVSVETSPPQTAAQDPQGQGRVRTGMAR 571
APR A + PS A P P+ QR + +PP A P G R
Sbjct: 148 APRAAAAAATAPPSPGPAQ-------PGPRAQRAAPLAAPPPAPAAPPAVAPPA--GPRR 198
Query: 572 SEDPAVLLGCQDSPRLKAVRPTSPPQDHRPTCPGL------GTKDALGLPGESPVKE--- 622
+ PAV ++ P +P +PPQ +P P G A G ++E
Sbjct: 199 APPPAV--AAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVR 256
Query: 623 ---SHGLAKGSSEETELPGMVYV-VGSHHRLRPWRLSQSPVPSSGLLSPGGRGPQGALQS 678
G A G + G++ + RL RL +P GR P A
Sbjct: 257 YLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRG---DRPGRAPPAASAR 313
Query: 679 PSAQKRG 685
PS KRG
Sbjct: 314 PSRSKRG 320
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 58.9 bits (141), Expect = 2e-08
Identities = 126/518 (24%), Positives = 173/518 (33%), Gaps = 92/518 (17%)
Query: 280 EKFLEFEAEEEMQIQKSQWMKGPQSLPPPAPPRLEPRGPP--APEVVKQPVYLPSKDGPK 337
E LE EEM + + P+ P PP P PP A + P LP+ P+
Sbjct: 427 EPQLEAPLNEEMPL-----LPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPE 481
Query: 338 APTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQE 397
A RP E PPP + P P P + PEE PP E
Sbjct: 482 ALHL-------SRPLEESPLSPPPE-ESPLSPPPESSPFSPLEESPLSPPEESPPSPALE 533
Query: 398 -----------YVDIMEELLGSHPGDTGEPEGQREKGKVEQPQEEDGITSDPGLLSYIDK 446
EE S P + E ++ P EE ++ P
Sbjct: 534 TPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPP-------- 585
Query: 447 LCSQEDFVTKVEAV-IHPRFLEELLSPDPQMDFLALSQELEQ----EEGLTLAQLVEKRL 501
+ EA + P F E LSP P+ L+ E + E ++ E+
Sbjct: 586 --EESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESP 643
Query: 502 LSLKEKGCGRAAPRHGTARLDSSPSEFAAGQEAAREVPDPQQRVSVETSPPQTAAQDPQG 561
+S + R +P +RL P E P S + PP+ + P
Sbjct: 644 MSPPPE-VSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPP 702
Query: 562 QGRVRTGMARSEDPAVLLGCQDSPRLK----------------AVRPTSPPQDHRPTCPG 605
+ ED + L ++SP L + RP P RP P
Sbjct: 703 ED--SPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPH 760
Query: 606 LGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRL---------SQ 656
L + P SP E L E P G H +P L
Sbjct: 761 LSPQ--AEEPHLSPQPEEPCLCAVPEEPHLSP---QAEGPHLSPQPEELHLSPQTEEPHL 815
Query: 657 SPVPSSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKS---KKRPLFGSPSPAEKTPH 713
SPVP LSP P+ + SP +++ LSP P + S +K PL SP P +
Sbjct: 816 SPVPEEPCLSP---QPEESHLSPQSEEPCLSPRPEESHLSPELEKPPL--SPRPEKPPEE 870
Query: 714 PG--------PGLRVSGEQSLAWGLGGPSQSQKRKGDP 743
PG P GE SL+ LG P+ S+ G+P
Sbjct: 871 PGQCPAPEELPLFPPPGEPSLSPLLGEPALSE--PGEP 906
Score = 56.2 bits (134), Expect = 1e-07
Identities = 111/484 (22%), Positives = 159/484 (32%), Gaps = 105/484 (21%)
Query: 302 PQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQR---PAETKAHL 358
P+ LP PP PP E P+ P ++ P + PPP R P E
Sbjct: 558 PEELPTSPPPEASRLSPPPEE---SPMSPPPEESPMS-----PPPEASRLFPPFEESPLS 609
Query: 359 PPPRP---QRPAETNAHLPPPR--PQRPAETKVPEEIPPE--------VVQEYVDIMEEL 405
PPP P E + PPP P P + P PPE VV EE
Sbjct: 610 PPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEES 669
Query: 406 LGSHPGDTGEPEGQREKGKVEQPQE-----------------EDGITSDPGLLSYIDKLC 448
S P + E ++ P E ED + S P S + L
Sbjct: 670 PLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLP 729
Query: 449 SQEDFVTKVEAV-IHPRFLEELLSPDPQMDFLALSQELEQEEGLTLAQLVEKRLLSLKEK 507
+ + E + PR E LSP P+ L+ + EE Q E L ++ E+
Sbjct: 730 EEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLS----PQAEEPHLSPQPEEPCLCAVPEE 785
Query: 508 GCGRAAPRHGTARLDSSPSEFAAGQEAAREVPDPQQRVSVETSPPQTAAQDPQGQGRVRT 567
+P+ L P E + P + P+ + PQ
Sbjct: 786 --PHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQ------- 836
Query: 568 GMARSEDPAVLLGCQD---SPRLK----AVRPTSPPQDHRPTCPGLGTKDALGLPGESPV 620
SE+P + ++ SP L+ + RP PP++ PG+ P
Sbjct: 837 ----SEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEE----------------PGQCPA 876
Query: 621 KESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQSPVPSSGLLSPGGRGPQGALQSPS 680
E L E P + ++G P SP+P LSP G PS
Sbjct: 877 PEELPLFPPPGE----PSLSPLLGEPALSEPGEPPLSPLPEELPLSPSG--------EPS 924
Query: 681 AQKRGLSPSPSPASKSKKRPLFGSPSPAEKTPHPGPGLRVSGEQSLAWGLGGPSQSQKRK 740
+ + P P P S P+ + +P P L GE +G G S +
Sbjct: 925 LSPQLMPPDPLPPPLS---PIITAAAP--------PALSPLGELEYPFGAKGDSDPESPL 973
Query: 741 GDPL 744
P+
Sbjct: 974 AAPI 977
Score = 45.1 bits (105), Expect = 2e-04
Identities = 44/135 (32%), Positives = 54/135 (40%), Gaps = 19/135 (14%)
Query: 301 GPQSLPPP---APPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAH 357
GPQ+ P A PR P+GPP + GP PT PP PQ P + +
Sbjct: 4268 GPQTGPLQELGAGPR--PQGPPRLPAPPGALSTGPVLGPVHPTP--PPSSPQEP-KRPSQ 4322
Query: 358 LPPPRPQRPAETNAHLPP-----PRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGD 412
LP P Q P E A LPP P+PQ P P + P Q + + L G
Sbjct: 4323 LPSPSSQLPTE--AQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQ----LADTLFSKGLGP 4376
Query: 413 TGEPEGQREKGKVEQ 427
P+ E K EQ
Sbjct: 4377 WDPPDNLAETQKPEQ 4391
Score = 42.4 bits (98), Expect = 0.002
Identities = 124/540 (22%), Positives = 175/540 (32%), Gaps = 130/540 (24%)
Query: 302 PQSLPP------PAPPRLEP--RGPPAPEVVKQPVYLPSKDGPKAPTA---CLPPPRPQR 350
P+SLP PA P+ + + P P + + PS P+ + PP RPQ
Sbjct: 2400 PRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQS 2459
Query: 351 PAETKAHLPPPRPQRP-----AETNAH-------LPPPRPQRPA---ETKVPEEIPPEVV 395
PPRPQ P A + AH P P PA KVP PP V
Sbjct: 2460 RDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFV 2519
Query: 396 QE-----YVDIMEELLGSHPGDTGEPEGQREKGKVEQP--QEEDGITSDPGLLSYIDKLC 448
+ +V + + P GEP K V QP GI S G + K
Sbjct: 2520 RSPGTGAFVGTPSPMRFTFPQAVGEPS---LKPPVPQPGLPPPHGINSHFGPGPTLGK-- 2574
Query: 449 SQEDFVTKVEAVIHP---------------------RFLEELLSPDPQMDFLALSQELEQ 487
Q T HP R L P P LS Q
Sbjct: 2575 PQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQ 2634
Query: 488 EEGLTLAQLVEKRLLSLKEKGCGRAAPRH----------GTARLDSSPSEFAAGQEAARE 537
G+T VEKR ++ G G + G + L + E ++ RE
Sbjct: 2635 RSGITSP--VEKR----EDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRE 2688
Query: 538 VPDPQQ------RVSVETSPPQTAAQDPQGQ-------------GRVRTGMARSEDPAVL 578
+ QQ R ET+ A P G R +T A ++D + L
Sbjct: 2689 LLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSL 2748
Query: 579 LGCQDSPRLKAV----------RPTSPPQDHRPTCPGLGTKDALG----------LPGES 618
+G S + R + PP P+ + ++ +G PG
Sbjct: 2749 VGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSL 2808
Query: 619 PVKESHGLAKGSSEETELPGMVYVVGSHHRLRPW-----RLSQSPV-------PSSGLLS 666
P+++ + T M + + + P + SP+ P G
Sbjct: 2809 PLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPV 2868
Query: 667 PGGRGPQGALQSPSAQKRGLSP--SPSPASKSKKRPLF--GSPSPAEKTPHPGPGLRVSG 722
PG GP ++ ++GL P +P P +RP F S P P GL VSG
Sbjct: 2869 PGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSG 2928
Score = 35.4 bits (80), Expect = 0.20
Identities = 106/456 (23%), Positives = 154/456 (33%), Gaps = 72/456 (15%)
Query: 300 KGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLP 359
+G + L P +P PPAPE+ P GP PT RP P+ T+ P
Sbjct: 2919 EGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRP--PSSTELGRP 2976
Query: 360 PPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPG-DTGEPEG 418
P A LP P+ + + + + EEL +H G +G
Sbjct: 2977 NPL----ALEAGKLPCEDPELDDDFDAHKALEDD---------EEL--AHLGLGVDVAKG 3021
Query: 419 QREKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMD- 477
E G +E + T+DP ++D L + ++F + L DP++D
Sbjct: 3022 DDELGTLENLE-----TNDP----HLDDLLNGDEF-------------DLLAYTDPELDT 3059
Query: 478 ----------FLALSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPSE 527
+ E+ E L + VE L +E+ A RL S E
Sbjct: 3060 GDKKDIFNEHLRLVESANEKAEREALLRGVEPGPLGPEER--PPPAADASEPRLASVLPE 3117
Query: 528 FAAGQEAAREVPDPQQRVSVETSPPQTAAQDPQGQG-RVRTGMARSEDPAVLLGCQDSPR 586
E P P Q A + G G + M S D + G S
Sbjct: 3118 VKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSG 3177
Query: 587 LKAVR----PTSPPQDHRPTCPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYV 642
A + T P H L T L PG S + E L G+ LPG
Sbjct: 3178 HTAEKASFGATGGPPAH------LLTPSPLSGPGGSSLLEKFELESGA---LTLPGGPAA 3228
Query: 643 VGSHHRLRPWRLSQSPVPSSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKKRPLF 702
G L S +P L+ + LQ L P+ + ++ L
Sbjct: 3229 SGDELDKMESSLVASELPL--LIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLL 3286
Query: 703 GSPSPAE--KTPHPGPGLRVSG-EQSLAWGLGGPSQ 735
+P PA+ PH G ++G +Q L+ GL G Q
Sbjct: 3287 SAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQ 3322
Score = 34.3 bits (77), Expect = 0.44
Identities = 28/96 (29%), Positives = 38/96 (39%), Gaps = 8/96 (8%)
Query: 302 PQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAE--TKAHLP 359
P LPPP P + PPA + + Y G P + L P + P +A+
Sbjct: 932 PDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCT 991
Query: 360 PPRPQRPAETNAHLPPP--RPQRPAETKVPEEIPPE 393
P P P LPP P PA + E +PP+
Sbjct: 992 DPEPVPP----MILPPSPGSPVGPASPILMEPLPPQ 1023
Score = 33.1 bits (74), Expect = 0.98
Identities = 24/71 (33%), Positives = 27/71 (38%), Gaps = 2/71 (2%)
Query: 309 APPRLEPRGPPAPEVVK--QPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQRP 366
APP EP PP+P P P + P P A P P P A + P RP
Sbjct: 4908 APPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARP 4967
Query: 367 AETNAHLPPPR 377
E PPR
Sbjct: 4968 PEEGEDSRPPR 4978
Score = 32.7 bits (73), Expect = 1.3
Identities = 47/181 (25%), Positives = 63/181 (34%), Gaps = 43/181 (23%)
Query: 60 PSTPLVAGQDGRGPSGAGASNVFVQMRTEV-------------GPVKPPQAQTLI----L 102
P P Q G+G G G Q+R ++ P + Q Q L+ L
Sbjct: 4172 PPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQL 4231
Query: 103 TQAPLV-----WQAPGT----LCGGVMCPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSH 153
Q+ V +Q PGT L G + C P L PG Q +G G
Sbjct: 4232 QQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQL--GGFPGPQTGPLQELGA-----GPRPQ 4284
Query: 154 GLP-LPPPPPAAQVAPIVSPGNARPWPQGAH---------GEGSLAPSQAKARPDDSCKP 203
G P LP PP A P++ P + P P S P++A+ P P
Sbjct: 4285 GPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTP 4344
Query: 204 K 204
K
Sbjct: 4345 K 4345
Score = 32.7 bits (73), Expect = 1.3
Identities = 19/62 (30%), Positives = 28/62 (45%), Gaps = 7/62 (11%)
Query: 306 PPPAPPRLEPRGPPAPEVVK---QPVYLPSKDGP----KAPTACLPPPRPQRPAETKAHL 358
PPP+P P PP +V+ +P+ P P +P + P PR + P E +
Sbjct: 4916 PPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSR 4975
Query: 359 PP 360
PP
Sbjct: 4976 PP 4977
Score = 32.0 bits (71), Expect = 2.2
Identities = 61/239 (25%), Positives = 89/239 (37%), Gaps = 56/239 (23%)
Query: 529 AAGQEAAREVPDPQQRVSVETSPPQ---TAAQDPQG-----QGRVRTGMARS---EDPAV 577
A G + R V + V SPP+ T +P QG+ + G S ++P
Sbjct: 352 AQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGP 411
Query: 578 L---------LGCQDSPRLKAV-------------RPTSPPQDHRPTCPGLGTKDALGLP 615
L G Q P+L+A P SPP + PT P P
Sbjct: 412 LQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPP 471
Query: 616 GE---SPVKESHGLAKGSSEETEL--PGMVYVVGSHHRLRPWR-LSQSPV-------PSS 662
E SP+ E+ L++ EE+ L P + P+ L +SP+ PS
Sbjct: 472 EELPASPLPEALHLSR-PLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSP 530
Query: 663 GLLSPGGRGPQGALQSPSAQKRGLSPSP-----SPASKSKKRPLFGSPSPAEKTPHPGP 716
L +P P+ + SP ++ LSP P SP ++ + SP P E P P
Sbjct: 531 ALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRL----SPPPEESPMSPPP 585
Score = 30.4 bits (67), Expect = 6.3
Identities = 25/76 (32%), Positives = 31/76 (40%), Gaps = 13/76 (17%)
Query: 122 PPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGNARPWPQG 181
PPP LA +P P T V T+ PL PP + + SP +ARP P+
Sbjct: 4916 PPPSPLAPSPASPPTEPLVELPTE----------PLAEPPVPSPLPLASSPESARPKPRA 4965
Query: 182 ---AHGEGSLAPSQAK 194
GE S P K
Sbjct: 4966 RPPEEGEDSRPPRLKK 4981
>gi|9945318 MAX binding protein [Homo sapiens]
Length = 582
Score = 58.5 bits (140), Expect = 2e-08
Identities = 98/407 (24%), Positives = 145/407 (35%), Gaps = 93/407 (22%)
Query: 28 LPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFPSTPLVAGQDGRGPSGAGASNVFVQMRT 87
LP + PAP PA PPL T P L+ P P+V
Sbjct: 65 LPLSPPAPPPAPPPPLAT-------PAPLTVIP-IPVVTNSP------------------ 98
Query: 88 EVGPVKPPQAQTLILTQAPLVWQAPGTL-CGGVMCPPPLLLAAAPGVPVTSAQVVGGTQA 146
P+ PP PL + P + G+ P L + P VP T A ++ ++A
Sbjct: 99 --QPLPPPPPLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVP-TPAPLLPDSKA 155
Query: 147 CEGGWSHGLPLPP-PPPAAQVAPI--VSPGNA-RPWPQGAHGEGSLAPSQAKARPDDSCK 202
PL P P P +AP V P A + P G LAP++ + +
Sbjct: 156 TIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKR 215
Query: 203 PKSVYENFRLWQHYKPLARRHLPQS--------PDTEALSCFLIPVLRSLARRKPTMTLE 254
P + + + R HL + P+ + + VLR+ R ++ +
Sbjct: 216 PGGIGTR-EVHNKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRK 274
Query: 255 EGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM--------------- 299
E +E++H +R+ EK + E++ + SQWM
Sbjct: 275 E------KEYEH--EMERL----AREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQP 322
Query: 300 -----------KGPQSLPPP--------APPRLEPRGPPAPEVVKQPVYLPSKDGPKAPT 340
+G ++ PP+L R P PE++K LP AP
Sbjct: 323 EDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHR--PQPELLKST--LPPPSTTPAPL 378
Query: 341 ACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVP 387
P P P A AHLP + Q +T PPP P PA+T VP
Sbjct: 379 PPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVP 425
Score = 32.7 bits (73), Expect = 1.3
Identities = 36/137 (26%), Positives = 48/137 (35%), Gaps = 31/137 (22%)
Query: 258 WQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQSLPPPAPPRLE--- 314
WQA ++ + +R L E E E + +K+ + P PR+E
Sbjct: 15 WQAQQQQRAREEQER----------LRLEQEREQEQKKANSLARLAHTLPVEEPRMEAPP 64
Query: 315 -PRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQR--PAETKAHLPPPRPQRPAETNA 371
P PPAP P AP L P P P + P P P P A
Sbjct: 65 LPLSPPAP--------------PPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAA 110
Query: 372 HLP-PPRPQRPAETKVP 387
P P P++PA P
Sbjct: 111 AQPLPLAPRQPALVGAP 127
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 57.4 bits (137), Expect = 5e-08
Identities = 147/661 (22%), Positives = 234/661 (35%), Gaps = 160/661 (24%)
Query: 86 RTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVMCPPPLLLAAAPGVPVTSAQVVGGTQ 145
+++ GP KPP AQ LT+ PL Q PGT+ PP+ PG AQ
Sbjct: 323 KSQPGPAKPP-AQPSGLTK-PLA-QQPGTV------KPPV---QPPGTTKPPAQ------ 364
Query: 146 ACEGGWSHGLPLPPPPPAAQVAPIVSPGNARPWPQGAHGEGSLAPSQAKARPDDSCKPKS 205
PL P P AQ P + +P P+ + + A+ +P + P
Sbjct: 365 ----------PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ-QPGPAKPPTQ 413
Query: 206 VYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWQAMREWQ 265
KPLA++ QSP +A PV + + P G A
Sbjct: 414 QVGT------PKPLAQQPGLQSP-AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSA----- 461
Query: 266 HTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQSLPPPAPPRLEPRGPPAPEVVK 325
Q++ K P LP PA P PP +
Sbjct: 462 ----------------------------QQTGPTKPPSQLPGPAKP------PP-----Q 482
Query: 326 QPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETK 385
QP P+K P+ P + PP Q+P TK PPP+ PA+ P PQ+P TK
Sbjct: 483 QPG--PAKPPPQQPGSAKPP--SQQPGSTK---PPPQQPGPAK-------PSPQQPGSTK 528
Query: 386 VPEEIPPEVVQEYVDIMEELLGSHPG--DTGEPEGQREKGKVEQPQEEDGITSDP---GL 440
P + P ++ + P + +P Q GK QP P GL
Sbjct: 529 PPSQQPGSAKPS----AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGL 584
Query: 441 LSYIDKLCSQEDFVTKVEAVIHPRFLEEL---------LSPDPQM----DFLALSQELEQ 487
I LC+ + + V + E +P+P + ++L L+ ++++
Sbjct: 585 PKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKR 644
Query: 488 EEGLTLAQLVEKRLLSLKEK--GCGRAAPRHGTARLDSSPSEFAAGQEAAREVPDPQ--- 542
G LA + LK A + +SP + AA ++ + P+P+
Sbjct: 645 ALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP 704
Query: 543 ---QRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDH 599
++ ++ SP A Q P+ +++ P P + + + +P D
Sbjct: 705 PLVKQPTLHGSPSAKAKQPPEAD-----SLSKPAPP-------KEPSVPSEQDKAPVADD 752
Query: 600 RPTCPGLGTKDALGLPGESPVKESHGLAKGSSEET--ELPGMVYVVGSHHRLRPWRLSQS 657
+P P + VK + L SS T ++P + + P + S
Sbjct: 753 KPKQPKM-------------VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDS 799
Query: 658 PVPSSGLLSPGGR---GPQGALQSPSAQKRGLS-PSPSPASKSKKRPLFGSPSPAEKTPH 713
PS G + A+ P++ + +S P PS SK +K+ P +K
Sbjct: 800 AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQ-----VDPVQKKEE 854
Query: 714 P 714
P
Sbjct: 855 P 855
Score = 52.8 bits (125), Expect = 1e-06
Identities = 161/780 (20%), Positives = 263/780 (33%), Gaps = 149/780 (19%)
Query: 8 PVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFPSTPLVAG 67
PV PG T P L GPA P T P+ S P +A
Sbjct: 352 PVQPPGTTKPPAQPL-------------GPAKPPAQQTGSEKPS-----SEQPGPKALAQ 393
Query: 68 QDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQ--------APGTLCGGV 119
G G + A + GP KPP Q + T PL Q APG V
Sbjct: 394 PPGVGKTPA----------QQPGPAKPPTQQ--VGTPKPLAQQPGLQSPAKAPGPTKTPV 441
Query: 120 MCPPPLLLAAAPGVP-VTSAQVVGGTQACEGGWSHGLPLP-------PPP--PAAQVAPI 169
P P + A P TSAQ G T+ P P PPP P + P
Sbjct: 442 QQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS 501
Query: 170 VSPGNARPWPQGAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPD 229
PG+ +P PQ G +P Q + S +P S + + KP A++
Sbjct: 502 QQPGSTKPPPQ-QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560
Query: 230 TEALSCFLIPVLRSLARRKPTMTLEEGL------WQAMREWQHTSNFD----------RM 273
T + P + A++ P+ L + + + + +NF+ +
Sbjct: 561 TGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSL 620
Query: 274 IFYEMAEKFLEFEAEEEMQIQKSQWMKGPQSLPPPAP-PRLE----------PRGPPAPE 322
+ E + + Q + + G + P +P P+L+ + P P+
Sbjct: 621 CGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQ 680
Query: 323 VVK-QPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRP 381
+ P +D KAP PPP ++P T P + ++P E ++ P P+ P
Sbjct: 681 QTSPKKDAAPKQDLSKAPEPKKPPPLVKQP--TLHGSPSAKAKQPPEADSLSKPAPPKEP 738
Query: 382 AETKVPEEIP--------PEVVQEYVDIMEELLGSHPGDTGEPEGQRE-KGKVEQPQEED 432
+ ++ P P++V+ D++ + D + Q + + K P + D
Sbjct: 739 SVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTD 798
Query: 433 GITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLS-PDPQMDFLALSQELEQEEGL 491
+K+ + +A+ P +++S P P + S+ +Q + +
Sbjct: 799 SAKPSQSFPPTGEKVSPFDS-----KAIPRPASDSKIISHPGPSSE----SKGQKQVDPV 849
Query: 492 TLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPSEFAAGQEAAREVPDPQQ-------- 543
+ +K + K + P+ SP+ A + VP PQQ
Sbjct: 850 QKKEEPKKAQTKMSPKPDAKPMPK-------GSPTPPGPRPTAGQTVPTPQQSPKPQEQS 902
Query: 544 -RVSVE----TSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQD 598
R S+ T P++ PQ TG ++ S + P
Sbjct: 903 RRFSLNLGSITDAPKSQPTTPQ---ETVTGKLFGFGASIF-----SQASNLISTAGQPGP 954
Query: 599 HRPTCPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQSP 658
H + PG K A P S S G K + + P V ++
Sbjct: 955 HSQSGPGAPMKQA---PAPSQPPTSQGPPKSTGQAPPAPAKSIPV----------KKETK 1001
Query: 659 VPSSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKKRPLFGS----PSPAEKTPHP 714
P++ L P A Q+P+ ++ P P SK P+ EK+P P
Sbjct: 1002 APAAEKLEP------KAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKP 1055
Score = 43.1 bits (100), Expect = 0.001
Identities = 95/439 (21%), Positives = 159/439 (36%), Gaps = 42/439 (9%)
Query: 304 SLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTAC---LPPPRPQRPAETKAHLPP 360
SLP P+ P ++ P P +QP + S+ GP P A L P Q+P K + P
Sbjct: 297 SLPSPSKPPIQQPTPGKPPA-QQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQP 355
Query: 361 PRPQR-PAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPG-------D 412
P + PA+ PP Q +E E+ P+ + + + + PG
Sbjct: 356 PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV-GKTPAQQPGPAKPPTQQ 414
Query: 413 TGEPEGQREKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEA-----VIHPRFLE 467
G P+ ++ ++ P + G T P K+ +Q+ K A P L
Sbjct: 415 VGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP 474
Query: 468 ELLSPDPQMDFLALSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPSE 527
P PQ ++ Q+ G + + G A P PS+
Sbjct: 475 GPAKPPPQQP--GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532
Query: 528 FAAGQEAAREVPDPQQRVSVETSPP--QTAA----QDPQGQGRVRTGMARSEDPAVLLGC 581
+ + + P P + + +++ P QT + Q P + ++ + C
Sbjct: 533 QPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLC 592
Query: 582 QDSPRLKAVRPTSPPQDHRPTCPGLGTKDALGLPGESP----VKESHGLAKGSSEETELP 637
+ L V P + + TC T L G +P + L + L
Sbjct: 593 NTTELLLHV----PEKANFNTCTECQT-TVCSLCGFNPNPHLTEVKEWLCLNCQMKRALG 647
Query: 638 GMVYVVGSHHRLRPWRLSQSPVPSSGLLSPGGRGP-QGALQSPSAQKRGLSPSPSPASKS 696
G + V S + +L +PV ++ +S P Q + + +A K+ LS +P P
Sbjct: 648 GDLAPVPSSPQP---KLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP 704
Query: 697 ---KKRPLFGSPSPAEKTP 712
K+ L GSPS K P
Sbjct: 705 PLVKQPTLHGSPSAKAKQP 723
Score = 42.7 bits (99), Expect = 0.001
Identities = 82/390 (21%), Positives = 137/390 (35%), Gaps = 70/390 (17%)
Query: 339 PTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEY 398
P A P R E + PP + RP P P RPA+ + + + +
Sbjct: 72 PPAAAESPSMHRKQELDSSHPPKQSGRP---------PDPGRPAQPGLSKSRTTDTFRS- 121
Query: 399 VDIMEELLGSHPGDTGEPEGQREKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVE 458
E+ L PG + +E +EE + PG LS ++ L + V K
Sbjct: 122 ----EQKL---PGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFN 174
Query: 459 AVIHPRFLEELLSPDPQMDFLALSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGT 518
+L+S E QEE ++V+K + K G P
Sbjct: 175 PF-------DLIS----------DSEASQEETTKKQKVVQKE----QGKPEGIIKPPLQQ 213
Query: 519 ARLDSSPSEFAAGQEAAREVPDPQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVL 578
P + G++ ++ P+ S+ + P+ P G G+ G ++
Sbjct: 214 QPPKPIPKQQGPGRDPLQQDGTPK---SISSQQPEKIKSQPPGTGKPIQGPTQTPQT--- 267
Query: 579 LGCQDSPRLKAVRPTSPPQDHRPTCP-GLGTKDALGLPGESPVKESHGLAKGSSEETELP 637
D +L R S PQ + G K +L P + P+++ + P
Sbjct: 268 ----DHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP----TPGKPPAQQP 319
Query: 638 GMVYVVGSHHRLRPWRLSQSPVPSSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSK 697
G H + +P ++ P SGL P + P G ++ P P +K
Sbjct: 320 G-------HEKSQPGP-AKPPAQPSGLTKPLAQQP-GTVKPPV--------QPPGTTKPP 362
Query: 698 KRPLFGSPSPAEKTPHPGPGLRVSGEQSLA 727
+PL + PA++T P G ++LA
Sbjct: 363 AQPLGPAKPPAQQTGSEKPSSEQPGPKALA 392
Score = 36.6 bits (83), Expect = 0.089
Identities = 67/320 (20%), Positives = 113/320 (35%), Gaps = 56/320 (17%)
Query: 331 PSKDGPKAPTACLPPPRPQRPAETKAHLPPPRP---QRPAETNAHLPPPRPQRPAETKVP 387
P+ GPKA P P P + K +PP ++ E ++ ET
Sbjct: 1127 PAPSGPKAS----PMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSM 1182
Query: 388 EEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQREKGKVEQPQEEDGITSDPGLLSYIDKL 447
E+IPP V D + E + EK K QE+ + + L+ +K+
Sbjct: 1183 EKIPPMVTT---------------DQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKI 1227
Query: 448 CSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLALSQELEQEEGLTLAQLVEKRLLSLKEK 507
S+E P E+ +P+ + +E+ L++ ++ +EK
Sbjct: 1228 RSEEK---------KPLLEEKKPTPEDKKLLPEAKTSAPEEQ---KHDLLKSQVQIAEEK 1275
Query: 508 GCGRAAP------RHGTARLDSSPSEFAAGQEAAREVPDPQQRVSVETSPPQTAAQDPQG 561
GR AP + +++ PS Q +E + + + PP TA D
Sbjct: 1276 LEGRVAPKTVQEGKQPQTKMEGLPS--GTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVE 1333
Query: 562 QGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDHRPTCPGLGTKDALG-LPGESPV 620
G+ +T + +D + Q + + T D G +LG +P P
Sbjct: 1334 PGKEKT--EKEDDKSDTSSSQQPKSPQGLSDTGYSSD--------GISSSLGEIPSLIPT 1383
Query: 621 KES---HGLAKGSSEETELP 637
E GL K S + P
Sbjct: 1384 DEKDILKGLKKDSFSQESSP 1403
Score = 35.8 bits (81), Expect = 0.15
Identities = 30/123 (24%), Positives = 40/123 (32%), Gaps = 31/123 (25%)
Query: 302 PQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSK---------------------------- 333
P PPP PP P P P +P LP K
Sbjct: 2410 PPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLR 2469
Query: 334 -DGPKAPTAC--LPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVPEEI 390
+G C PPP P +P+ + L P++ P PQ P T+ P +I
Sbjct: 2470 SNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDI 2529
Query: 391 PPE 393
P+
Sbjct: 2530 HPK 2532
Score = 33.5 bits (75), Expect = 0.75
Identities = 83/355 (23%), Positives = 124/355 (34%), Gaps = 74/355 (20%)
Query: 322 EVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRP 381
E VK + PSK + PT PP Q+P K+ P P +P + L P Q+P
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPA--QQPGHEKSQ---PGPAKPPAQPSGLTKPLAQQP 346
Query: 382 AETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQR---EKGKVEQPQEEDGITSDP 438
K P + PP + + P +P Q+ EK EQP + + P
Sbjct: 347 GTVKPPVQ-PPGTTKP---------PAQPLGPAKPPAQQTGSEKPSSEQPGPK-ALAQPP 395
Query: 439 GLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLALSQELEQEEGL-TLAQLV 497
G + K +Q+ K P + + L Q+ GL + A+
Sbjct: 396 G----VGKTPAQQPGPAK-----------------PPTQQVGTPKPLAQQPGLQSPAKAP 434
Query: 498 EKRLLSLKEKGCGRAAPRHG----TARLDSSPSEFAAGQEAAREVPDPQQRVSVETSPPQ 553
+++ G G+ + T+ + P++ Q P PQQ + P Q
Sbjct: 435 GPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTK-PPSQLPGPAKPPPQQPGPAKPPPQQ 493
Query: 554 TAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSP-PQDHRPTCPGLGTKDAL 612
+ P Q P P P P P PG TK
Sbjct: 494 PGSAKPPSQ---------------------QPGSTKPPPQQPGPAKPSPQQPG-STKPPS 531
Query: 613 GLPGES-PVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQS--PVPSSGL 664
PG + P + AK S++++ P V GS L+P +S S PS GL
Sbjct: 532 QQPGSAKPSAQQPSPAKPSAQQSTKP--VSQTGSGKPLQPPTVSPSAKQPPSQGL 584
Score = 31.6 bits (70), Expect = 2.8
Identities = 90/421 (21%), Positives = 141/421 (33%), Gaps = 76/421 (18%)
Query: 302 PQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPP 361
P+S+ P +++ + P + ++ P P D K P RPQ
Sbjct: 236 PKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQ-RDASRPQTKQADIVRGESV 294
Query: 362 RPQRPAETNAHLPPPRPQR-PAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQR 420
+P P+ + + P P + PA+ E+ P + + P +P Q
Sbjct: 295 KPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP---------PAQPSGLTKPLAQ- 344
Query: 421 EKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLA 480
+ G V+ P + G T P K +Q+ K + P P+ A
Sbjct: 345 QPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE----------QPGPK----A 390
Query: 481 LSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPSEFA--AGQEAAREV 538
L+Q G T AQ + P + +P A G ++ +
Sbjct: 391 LAQ--PPGVGKTPAQ---------------QPGPAKPPTQQVGTPKPLAQQPGLQSPAKA 433
Query: 539 PDPQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQD 598
P P + + P + AQ G G+ P L P + P PP
Sbjct: 434 PGPTKTPVQQPGPGKIPAQQ-AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP-- 490
Query: 599 HRPTCPGLGTKDALGLPGES-PVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQS 657
P PG K PG + P + G AK S ++ PG ++
Sbjct: 491 --PQQPG-SAKPPSQQPGSTKPPPQQPGPAKPSPQQ---PGS---------------TKP 529
Query: 658 PVPSSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKKRPLFGSPSPAEKTPHPGPG 717
P G P + P A PSAQ+ S + + K + P + SP+ K P P G
Sbjct: 530 PSQQPGSAKPSAQQPSPA--KPSAQQSTKPVSQTGSGKPLQPP---TVSPSAKQP-PSQG 583
Query: 718 L 718
L
Sbjct: 584 L 584
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 57.4 bits (137), Expect = 5e-08
Identities = 147/661 (22%), Positives = 234/661 (35%), Gaps = 160/661 (24%)
Query: 86 RTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVMCPPPLLLAAAPGVPVTSAQVVGGTQ 145
+++ GP KPP AQ LT+ PL Q PGT+ PP+ PG AQ
Sbjct: 323 KSQPGPAKPP-AQPSGLTK-PLA-QQPGTV------KPPV---QPPGTTKPPAQ------ 364
Query: 146 ACEGGWSHGLPLPPPPPAAQVAPIVSPGNARPWPQGAHGEGSLAPSQAKARPDDSCKPKS 205
PL P P AQ P + +P P+ + + A+ +P + P
Sbjct: 365 ----------PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ-QPGPAKPPTQ 413
Query: 206 VYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWQAMREWQ 265
KPLA++ QSP +A PV + + P G A
Sbjct: 414 QVGT------PKPLAQQPGLQSP-AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSA----- 461
Query: 266 HTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQSLPPPAPPRLEPRGPPAPEVVK 325
Q++ K P LP PA P PP +
Sbjct: 462 ----------------------------QQTGPTKPPSQLPGPAKP------PP-----Q 482
Query: 326 QPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETK 385
QP P+K P+ P + PP Q+P TK PPP+ PA+ P PQ+P TK
Sbjct: 483 QPG--PAKPPPQQPGSAKPP--SQQPGSTK---PPPQQPGPAK-------PSPQQPGSTK 528
Query: 386 VPEEIPPEVVQEYVDIMEELLGSHPG--DTGEPEGQREKGKVEQPQEEDGITSDP---GL 440
P + P ++ + P + +P Q GK QP P GL
Sbjct: 529 PPSQQPGSAKPS----AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGL 584
Query: 441 LSYIDKLCSQEDFVTKVEAVIHPRFLEEL---------LSPDPQM----DFLALSQELEQ 487
I LC+ + + V + E +P+P + ++L L+ ++++
Sbjct: 585 PKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKR 644
Query: 488 EEGLTLAQLVEKRLLSLKEK--GCGRAAPRHGTARLDSSPSEFAAGQEAAREVPDPQ--- 542
G LA + LK A + +SP + AA ++ + P+P+
Sbjct: 645 ALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP 704
Query: 543 ---QRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDH 599
++ ++ SP A Q P+ +++ P P + + + +P D
Sbjct: 705 PLVKQPTLHGSPSAKAKQPPEAD-----SLSKPAPP-------KEPSVPSEQDKAPVADD 752
Query: 600 RPTCPGLGTKDALGLPGESPVKESHGLAKGSSEET--ELPGMVYVVGSHHRLRPWRLSQS 657
+P P + VK + L SS T ++P + + P + S
Sbjct: 753 KPKQPKM-------------VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDS 799
Query: 658 PVPSSGLLSPGGR---GPQGALQSPSAQKRGLS-PSPSPASKSKKRPLFGSPSPAEKTPH 713
PS G + A+ P++ + +S P PS SK +K+ P +K
Sbjct: 800 AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQ-----VDPVQKKEE 854
Query: 714 P 714
P
Sbjct: 855 P 855
Score = 52.8 bits (125), Expect = 1e-06
Identities = 161/780 (20%), Positives = 263/780 (33%), Gaps = 149/780 (19%)
Query: 8 PVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFPSTPLVAG 67
PV PG T P L GPA P T P+ S P +A
Sbjct: 352 PVQPPGTTKPPAQPL-------------GPAKPPAQQTGSEKPS-----SEQPGPKALAQ 393
Query: 68 QDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQ--------APGTLCGGV 119
G G + A + GP KPP Q + T PL Q APG V
Sbjct: 394 PPGVGKTPA----------QQPGPAKPPTQQ--VGTPKPLAQQPGLQSPAKAPGPTKTPV 441
Query: 120 MCPPPLLLAAAPGVP-VTSAQVVGGTQACEGGWSHGLPLP-------PPP--PAAQVAPI 169
P P + A P TSAQ G T+ P P PPP P + P
Sbjct: 442 QQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS 501
Query: 170 VSPGNARPWPQGAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPD 229
PG+ +P PQ G +P Q + S +P S + + KP A++
Sbjct: 502 QQPGSTKPPPQ-QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560
Query: 230 TEALSCFLIPVLRSLARRKPTMTLEEGL------WQAMREWQHTSNFD----------RM 273
T + P + A++ P+ L + + + + +NF+ +
Sbjct: 561 TGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSL 620
Query: 274 IFYEMAEKFLEFEAEEEMQIQKSQWMKGPQSLPPPAP-PRLE----------PRGPPAPE 322
+ E + + Q + + G + P +P P+L+ + P P+
Sbjct: 621 CGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQ 680
Query: 323 VVK-QPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRP 381
+ P +D KAP PPP ++P T P + ++P E ++ P P+ P
Sbjct: 681 QTSPKKDAAPKQDLSKAPEPKKPPPLVKQP--TLHGSPSAKAKQPPEADSLSKPAPPKEP 738
Query: 382 AETKVPEEIP--------PEVVQEYVDIMEELLGSHPGDTGEPEGQRE-KGKVEQPQEED 432
+ ++ P P++V+ D++ + D + Q + + K P + D
Sbjct: 739 SVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTD 798
Query: 433 GITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLS-PDPQMDFLALSQELEQEEGL 491
+K+ + +A+ P +++S P P + S+ +Q + +
Sbjct: 799 SAKPSQSFPPTGEKVSPFDS-----KAIPRPASDSKIISHPGPSSE----SKGQKQVDPV 849
Query: 492 TLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPSEFAAGQEAAREVPDPQQ-------- 543
+ +K + K + P+ SP+ A + VP PQQ
Sbjct: 850 QKKEEPKKAQTKMSPKPDAKPMPK-------GSPTPPGPRPTAGQTVPTPQQSPKPQEQS 902
Query: 544 -RVSVE----TSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQD 598
R S+ T P++ PQ TG ++ S + P
Sbjct: 903 RRFSLNLGSITDAPKSQPTTPQ---ETVTGKLFGFGASIF-----SQASNLISTAGQPGP 954
Query: 599 HRPTCPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQSP 658
H + PG K A P S S G K + + P V ++
Sbjct: 955 HSQSGPGAPMKQA---PAPSQPPTSQGPPKSTGQAPPAPAKSIPV----------KKETK 1001
Query: 659 VPSSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKKRPLFGS----PSPAEKTPHP 714
P++ L P A Q+P+ ++ P P SK P+ EK+P P
Sbjct: 1002 APAAEKLEP------KAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKP 1055
Score = 43.1 bits (100), Expect = 0.001
Identities = 95/439 (21%), Positives = 159/439 (36%), Gaps = 42/439 (9%)
Query: 304 SLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTAC---LPPPRPQRPAETKAHLPP 360
SLP P+ P ++ P P +QP + S+ GP P A L P Q+P K + P
Sbjct: 297 SLPSPSKPPIQQPTPGKPPA-QQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQP 355
Query: 361 PRPQR-PAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPG-------D 412
P + PA+ PP Q +E E+ P+ + + + + PG
Sbjct: 356 PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV-GKTPAQQPGPAKPPTQQ 414
Query: 413 TGEPEGQREKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEA-----VIHPRFLE 467
G P+ ++ ++ P + G T P K+ +Q+ K A P L
Sbjct: 415 VGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP 474
Query: 468 ELLSPDPQMDFLALSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPSE 527
P PQ ++ Q+ G + + G A P PS+
Sbjct: 475 GPAKPPPQQP--GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532
Query: 528 FAAGQEAAREVPDPQQRVSVETSPP--QTAA----QDPQGQGRVRTGMARSEDPAVLLGC 581
+ + + P P + + +++ P QT + Q P + ++ + C
Sbjct: 533 QPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLC 592
Query: 582 QDSPRLKAVRPTSPPQDHRPTCPGLGTKDALGLPGESP----VKESHGLAKGSSEETELP 637
+ L V P + + TC T L G +P + L + L
Sbjct: 593 NTTELLLHV----PEKANFNTCTECQT-TVCSLCGFNPNPHLTEVKEWLCLNCQMKRALG 647
Query: 638 GMVYVVGSHHRLRPWRLSQSPVPSSGLLSPGGRGP-QGALQSPSAQKRGLSPSPSPASKS 696
G + V S + +L +PV ++ +S P Q + + +A K+ LS +P P
Sbjct: 648 GDLAPVPSSPQP---KLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP 704
Query: 697 ---KKRPLFGSPSPAEKTP 712
K+ L GSPS K P
Sbjct: 705 PLVKQPTLHGSPSAKAKQP 723
Score = 42.7 bits (99), Expect = 0.001
Identities = 82/390 (21%), Positives = 137/390 (35%), Gaps = 70/390 (17%)
Query: 339 PTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEY 398
P A P R E + PP + RP P P RPA+ + + + +
Sbjct: 72 PPAAAESPSMHRKQELDSSHPPKQSGRP---------PDPGRPAQPGLSKSRTTDTFRS- 121
Query: 399 VDIMEELLGSHPGDTGEPEGQREKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVE 458
E+ L PG + +E +EE + PG LS ++ L + V K
Sbjct: 122 ----EQKL---PGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFN 174
Query: 459 AVIHPRFLEELLSPDPQMDFLALSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGT 518
+L+S E QEE ++V+K + K G P
Sbjct: 175 PF-------DLIS----------DSEASQEETTKKQKVVQKE----QGKPEGIIKPPLQQ 213
Query: 519 ARLDSSPSEFAAGQEAAREVPDPQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVL 578
P + G++ ++ P+ S+ + P+ P G G+ G ++
Sbjct: 214 QPPKPIPKQQGPGRDPLQQDGTPK---SISSQQPEKIKSQPPGTGKPIQGPTQTPQT--- 267
Query: 579 LGCQDSPRLKAVRPTSPPQDHRPTCP-GLGTKDALGLPGESPVKESHGLAKGSSEETELP 637
D +L R S PQ + G K +L P + P+++ + P
Sbjct: 268 ----DHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP----TPGKPPAQQP 319
Query: 638 GMVYVVGSHHRLRPWRLSQSPVPSSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSK 697
G H + +P ++ P SGL P + P G ++ P P +K
Sbjct: 320 G-------HEKSQPGP-AKPPAQPSGLTKPLAQQP-GTVKPPV--------QPPGTTKPP 362
Query: 698 KRPLFGSPSPAEKTPHPGPGLRVSGEQSLA 727
+PL + PA++T P G ++LA
Sbjct: 363 AQPLGPAKPPAQQTGSEKPSSEQPGPKALA 392
Score = 36.6 bits (83), Expect = 0.089
Identities = 67/320 (20%), Positives = 113/320 (35%), Gaps = 56/320 (17%)
Query: 331 PSKDGPKAPTACLPPPRPQRPAETKAHLPPPRP---QRPAETNAHLPPPRPQRPAETKVP 387
P+ GPKA P P P + K +PP ++ E ++ ET
Sbjct: 1127 PAPSGPKAS----PMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSM 1182
Query: 388 EEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQREKGKVEQPQEEDGITSDPGLLSYIDKL 447
E+IPP V D + E + EK K QE+ + + L+ +K+
Sbjct: 1183 EKIPPMVTT---------------DQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKI 1227
Query: 448 CSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLALSQELEQEEGLTLAQLVEKRLLSLKEK 507
S+E P E+ +P+ + +E+ L++ ++ +EK
Sbjct: 1228 RSEEK---------KPLLEEKKPTPEDKKLLPEAKTSAPEEQ---KHDLLKSQVQIAEEK 1275
Query: 508 GCGRAAP------RHGTARLDSSPSEFAAGQEAAREVPDPQQRVSVETSPPQTAAQDPQG 561
GR AP + +++ PS Q +E + + + PP TA D
Sbjct: 1276 LEGRVAPKTVQEGKQPQTKMEGLPS--GTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVE 1333
Query: 562 QGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDHRPTCPGLGTKDALG-LPGESPV 620
G+ +T + +D + Q + + T D G +LG +P P
Sbjct: 1334 PGKEKT--EKEDDKSDTSSSQQPKSPQGLSDTGYSSD--------GISSSLGEIPSLIPT 1383
Query: 621 KES---HGLAKGSSEETELP 637
E GL K S + P
Sbjct: 1384 DEKDILKGLKKDSFSQESSP 1403
Score = 35.8 bits (81), Expect = 0.15
Identities = 30/123 (24%), Positives = 40/123 (32%), Gaps = 31/123 (25%)
Query: 302 PQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSK---------------------------- 333
P PPP PP P P P +P LP K
Sbjct: 2410 PPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLR 2469
Query: 334 -DGPKAPTAC--LPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVPEEI 390
+G C PPP P +P+ + L P++ P PQ P T+ P +I
Sbjct: 2470 SNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDI 2529
Query: 391 PPE 393
P+
Sbjct: 2530 HPK 2532
Score = 33.5 bits (75), Expect = 0.75
Identities = 83/355 (23%), Positives = 124/355 (34%), Gaps = 74/355 (20%)
Query: 322 EVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRP 381
E VK + PSK + PT PP Q+P K+ P P +P + L P Q+P
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPA--QQPGHEKSQ---PGPAKPPAQPSGLTKPLAQQP 346
Query: 382 AETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQR---EKGKVEQPQEEDGITSDP 438
K P + PP + + P +P Q+ EK EQP + + P
Sbjct: 347 GTVKPPVQ-PPGTTKP---------PAQPLGPAKPPAQQTGSEKPSSEQPGPK-ALAQPP 395
Query: 439 GLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLALSQELEQEEGL-TLAQLV 497
G + K +Q+ K P + + L Q+ GL + A+
Sbjct: 396 G----VGKTPAQQPGPAK-----------------PPTQQVGTPKPLAQQPGLQSPAKAP 434
Query: 498 EKRLLSLKEKGCGRAAPRHG----TARLDSSPSEFAAGQEAAREVPDPQQRVSVETSPPQ 553
+++ G G+ + T+ + P++ Q P PQQ + P Q
Sbjct: 435 GPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTK-PPSQLPGPAKPPPQQPGPAKPPPQQ 493
Query: 554 TAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSP-PQDHRPTCPGLGTKDAL 612
+ P Q P P P P P PG TK
Sbjct: 494 PGSAKPPSQ---------------------QPGSTKPPPQQPGPAKPSPQQPG-STKPPS 531
Query: 613 GLPGES-PVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQS--PVPSSGL 664
PG + P + AK S++++ P V GS L+P +S S PS GL
Sbjct: 532 QQPGSAKPSAQQPSPAKPSAQQSTKP--VSQTGSGKPLQPPTVSPSAKQPPSQGL 584
Score = 31.6 bits (70), Expect = 2.8
Identities = 90/421 (21%), Positives = 141/421 (33%), Gaps = 76/421 (18%)
Query: 302 PQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPP 361
P+S+ P +++ + P + ++ P P D K P RPQ
Sbjct: 236 PKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQ-RDASRPQTKQADIVRGESV 294
Query: 362 RPQRPAETNAHLPPPRPQR-PAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQR 420
+P P+ + + P P + PA+ E+ P + + P +P Q
Sbjct: 295 KPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP---------PAQPSGLTKPLAQ- 344
Query: 421 EKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLA 480
+ G V+ P + G T P K +Q+ K + P P+ A
Sbjct: 345 QPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE----------QPGPK----A 390
Query: 481 LSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPSEFA--AGQEAAREV 538
L+Q G T AQ + P + +P A G ++ +
Sbjct: 391 LAQ--PPGVGKTPAQ---------------QPGPAKPPTQQVGTPKPLAQQPGLQSPAKA 433
Query: 539 PDPQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQD 598
P P + + P + AQ G G+ P L P + P PP
Sbjct: 434 PGPTKTPVQQPGPGKIPAQQ-AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP-- 490
Query: 599 HRPTCPGLGTKDALGLPGES-PVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQS 657
P PG K PG + P + G AK S ++ PG ++
Sbjct: 491 --PQQPG-SAKPPSQQPGSTKPPPQQPGPAKPSPQQ---PGS---------------TKP 529
Query: 658 PVPSSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKKRPLFGSPSPAEKTPHPGPG 717
P G P + P A PSAQ+ S + + K + P + SP+ K P P G
Sbjct: 530 PSQQPGSAKPSAQQPSPA--KPSAQQSTKPVSQTGSGKPLQPP---TVSPSAKQP-PSQG 583
Query: 718 L 718
L
Sbjct: 584 L 584
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 56.6 bits (135), Expect = 8e-08
Identities = 152/698 (21%), Positives = 227/698 (32%), Gaps = 124/698 (17%)
Query: 75 GAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVMCPPP-----LLLAA 129
GAGA + ++ P PP AQ+ T L+ +A G V+ PPP +L+
Sbjct: 750 GAGAKELGAFLQKSPPP-PPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSH 808
Query: 130 APGVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGNARPWPQGAHGEGSLA 189
AP ++++V G E G P PPPPP P+ A +HG A
Sbjct: 809 APSPSPSASKV--GVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAH---LRSHGLEPAA 863
Query: 190 PSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHL----PQSPDTEALSCFLIPVLRSLA 245
PS + RP++S P + P A P S + + P +
Sbjct: 864 PSP-RLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTK 922
Query: 246 RRK----PTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKG 301
+ ++ + L Q + +R F M E F A++ + +
Sbjct: 923 APRFVPLTSICFPDSLLQ---------DEERSFFPTMEEMFGGGAADDYGKAGPPEDEGD 973
Query: 302 PQSL--PPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRP-QRPAETKAH- 357
P++ PPP PP +P GP P S GP+ P L P +P + P+ A
Sbjct: 974 PKAGAGPPPGPPAYDPYGPYCPGRA-------SGAGPETPGLGLDPNKPPELPSTVNAEP 1026
Query: 358 -----------LPPPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELL 406
PPP P PPP P PA P + +
Sbjct: 1027 LGLIQSGPHQAAPPPPP----------PPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTS 1076
Query: 407 GSHPGDTGEPEGQREKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFL 466
H +P Q K Q E + ++ + ++PR L
Sbjct: 1077 SFHLLRRRDPPFQTPKKLYAQEYEFEA---------------DEDKADVPADIRLNPRRL 1121
Query: 467 EELLSPDPQMDFLALSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPS 526
+L+S L+ ++ + G R + A+ D P
Sbjct: 1122 PDLVS------------SCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPR 1169
Query: 527 EFAAGQEAAREVPDPQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPR 586
G+ R + P S P A+ P+G+GR G R + A R
Sbjct: 1170 P--RGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGR---GRGRKAEEA------GGTR 1218
Query: 587 LKAVRPTSPPQDHRPTCPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSH 646
L+ ++P GLGT + G H S ++ + V
Sbjct: 1219 LEPLKPLKIKLSVPKAGEGLGTSSGDAISG-----TDHNSLDSSLTREKIEAKIKEV--- 1270
Query: 647 HRLRPWRLSQSPVPSSGLLSPGGRGP---QGALQSPSAQKRGLSPSPSPASKSKKRPLFG 703
+P S L G R P Q L P LSP S R L
Sbjct: 1271 EEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPP------LSPPKSVPPSVPARGLQP 1324
Query: 704 SPSPAEKTPHPGPGLRVSGEQSLAWGLGGPSQSQKRKG 741
P PHP P S A+GLGG ++ + +G
Sbjct: 1325 QPPATPAVPHPPP--------SGAFGLGGALEAAESEG 1354
Score = 55.8 bits (133), Expect = 1e-07
Identities = 97/413 (23%), Positives = 147/413 (35%), Gaps = 51/413 (12%)
Query: 302 PQSLPPPAP-PRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPP 360
P PPPAP P+ +P PP P QP LPS APT PPP P P A P
Sbjct: 1457 PPPTPPPAPTPQPQPPPPPPP---PQPA-LPSPPPLVAPTPSSPPPPPLPPPPPPAMPSP 1512
Query: 361 PRPQRPAETNAHLPPPRPQRPA--ETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEG 418
P P PA PP P P+ + ++P+ P + + ++ + G+T E G
Sbjct: 1513 PPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAK------KQETAAVCGETDEEAG 1566
Query: 419 QREKGKVEQPQEEDGI-TSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMD 477
+ + + ++E I D L + + + +V+ + +F E+ D Q
Sbjct: 1567 ESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEI--KDGQRQ 1624
Query: 478 FLALSQELEQ--EEGLTLAQLVEKRLLSLKEKG----CGRA---APRHGTARLDSSPSEF 528
F A S L + +L K L ++ +K C R P R + +
Sbjct: 1625 FCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPV 1684
Query: 529 AAGQEAAREVPDPQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLK 588
+AG +A P ET P +T ++ P Q A E PA + P L
Sbjct: 1685 SAGGSSAPPPKAPAPPPKPET-PEKTTSEKPPEQ---TPETAMPEPPA-----PEKPSL- 1734
Query: 589 AVRPTSPPQDHRPTCPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSHHR 648
+RP ++ G + LA G + LP +
Sbjct: 1735 -LRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLP----------K 1783
Query: 649 LRPWRLSQSPVP---SSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKK 698
RP ++ P P L GG G P SP S+ ++
Sbjct: 1784 ARPTKVKAEPPPKKRKKWLKEAGGNATAGG--GPPGSSSDSESSPGAPSEDER 1834
Score = 48.9 bits (115), Expect = 2e-05
Identities = 94/403 (23%), Positives = 138/403 (34%), Gaps = 106/403 (26%)
Query: 8 PVLGPGVTVNP-GTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFPSTPLVA 66
P+ GP T P G L+ A+P P PG P + P PL+ P TP A
Sbjct: 1409 PLAGPKDTSTPDGPPLAPAAAVPGPPPLPGL----PSANSNGTPEPPLLEEKPPPTPPPA 1464
Query: 67 GQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVMCPPPLL 126
P P PP Q + + PLV P + PPP
Sbjct: 1465 PTPQPQP-----------------PPPPPPPQPALPSPPPLVAPTPSS-------PPPPP 1500
Query: 127 LAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGN--ARPWPQGAHG 184
L P +P PPPPP AP+ +P A P P+
Sbjct: 1501 LPPPP--------------------PPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPEL 1540
Query: 185 EGS----LAPSQAKA----RPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCF 236
+ LA Q A D+ FR + + ++ D +L
Sbjct: 1541 PDTRPLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEF-------VIRAEDIPSLKL- 1592
Query: 237 LIPVLRSLARRKPTMTLEEGLWQ--------AMREWQHTSNF------DRMIFYEMAEKF 282
L++ P +++ L Q R++ TSN+ + + + KF
Sbjct: 1593 ---ALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKF 1649
Query: 283 LEFEAEEEMQIQKSQWMKGPQSLP---PPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAP 339
LE + K +++ P PP P R + K PV P P
Sbjct: 1650 LE-------NVNKKDYVRVCARKPWHRPPVPVRRSGQ-------AKNPVSAGGSSAP-PP 1694
Query: 340 TACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPA 382
A PPP+P+ P +T + P P++ ET A PP P++P+
Sbjct: 1695 KAPAPPPKPETPEKTTSEKP---PEQTPET-AMPEPPAPEKPS 1733
Score = 42.0 bits (97), Expect = 0.002
Identities = 33/94 (35%), Positives = 35/94 (37%), Gaps = 15/94 (15%)
Query: 306 PPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACL----PPPRPQRPAETKAHLPPP 361
PP AP P PP P LPS + P L PPP P PA T PPP
Sbjct: 1422 PPLAPAAAVPGPPPLPG-------LPSANSNGTPEPPLLEEKPPPTPP-PAPTPQPQPPP 1473
Query: 362 RPQRPAETNAHLPP---PRPQRPAETKVPEEIPP 392
P P PP P P P +P PP
Sbjct: 1474 PPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPP 1507
Score = 33.9 bits (76), Expect = 0.57
Identities = 42/153 (27%), Positives = 56/153 (36%), Gaps = 9/153 (5%)
Query: 29 PFATPAPGPAHRPPLVTAVVPPAGPLVLSAFPSTPLVAGQDGRGPSGAGASNVFVQMRTE 88
PF+ PA G P V + P P V S+ L AG GP+G G +
Sbjct: 174 PFSPPANGLLS-PHDVLHLKPSQAPTVPSSLGFERL-AGGGVLGPAGLGPAQT---PPYR 228
Query: 89 VGPVKPPQAQTLILTQAPLVWQAPGTLCGGVMCPPPL--LLAAAPGVPVTSAQVVGGTQA 146
GP PP + TQ L+ + P L AAPG P +
Sbjct: 229 PGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTV 288
Query: 147 CEGGW--SHGLPLPPPPPAAQVAPIVSPGNARP 177
+ + P PPPPPA + +S G + P
Sbjct: 289 IKHYQRPASAQPPPPPPPAHALQHYLSCGGSYP 321
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
Length = 2462
Score = 55.8 bits (133), Expect = 1e-07
Identities = 112/451 (24%), Positives = 154/451 (34%), Gaps = 57/451 (12%)
Query: 306 PPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQR 365
PPP PP P PAP +P P+ + APT PPP P P+ +P +
Sbjct: 761 PPPGPPTPPPEDIPAPT---EPT--PASEATGAPT---PPPAPPSPSAPPPVVPKEEKEE 812
Query: 366 ------PAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQ 419
P E PP + A E P V E + EE G G E
Sbjct: 813 ETAAAPPVEEGEEQKPPAAEELAVDTGKAEEP--VKSECTEEAEE--GPAKGKDAEAAEA 868
Query: 420 REKGKVEQPQEEDGI-------TSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSP 472
+G ++ ++E G +S S CS ++ V + E R LLSP
Sbjct: 869 TAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADE-VDEAEGGDKNR----LLSP 923
Query: 473 DPQMDFLALSQELEQEEGLTLAQLVEKRLLSLKE-KGCGRAAPRHGTARLDSSPSEFAAG 531
P L G A ++ L LK+ K A P ++ P E AA
Sbjct: 924 RPS---------LLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAP 974
Query: 532 QEAAREVPDPQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVR 591
+ A P P Q + E+ PQ P+G+ R A E + P A
Sbjct: 975 TKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVF----FPAFAAEA 1030
Query: 592 PTSPPQDHRPTCPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSHHRLRP 651
P P C G +P +K S S+ PG +G H RP
Sbjct: 1031 QKLPGD---PPCWTSGL--PFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARP 1085
Query: 652 WRLSQSPVPSSGLLSPGGRGPQGALQSPSAQKRGLSPS-PSPASKSKKRPL----FGSPS 706
+ + L + P + A +G+S P S+ K P+ G P
Sbjct: 1086 VLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPL 1145
Query: 707 PAE-KTPHPGPGLRVSGEQSLAWGLGGPSQS 736
P + K P G V EQ G GP +S
Sbjct: 1146 PMDPKKLAPFSG--VKQEQLSPRGQAGPPES 1174
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
Length = 2524
Score = 54.7 bits (130), Expect = 3e-07
Identities = 111/450 (24%), Positives = 153/450 (34%), Gaps = 56/450 (12%)
Query: 306 PPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQR 365
PPP PP P PAP +P P+ + APT PPP P P+ +P +
Sbjct: 778 PPPGPPTPPPEDIPAPT---EPT--PASEATGAPT---PPPAPPSPSAPPPVVPKEEKEE 829
Query: 366 ------PAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQ 419
P E PP + A E P V E + EE G G E
Sbjct: 830 ETAAAPPVEEGEEQKPPAAEELAVDTGKAEEP--VKSECTEEAEE--GPAKGKDAEAAEA 885
Query: 420 REKGKVEQPQEEDGI-------TSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSP 472
+G ++ ++E G +S S CS ++ V + E R LLSP
Sbjct: 886 TAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADE-VDEAEGGDKNR----LLSP 940
Query: 473 DPQMDFLALSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPSEFAAGQ 532
P L G A ++ L LK+ AA ++ P E AA
Sbjct: 941 RPS---------LLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPT 991
Query: 533 EAAREVPDPQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRP 592
+ A P P Q + E+ PQ P+G+ R A E + P A
Sbjct: 992 KPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVF----FPAFAAEAQ 1047
Query: 593 TSPPQDHRPTCPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSHHRLRPW 652
P P C G +P +K S S+ PG +G H RP
Sbjct: 1048 KLPGD---PPCWTSGL--PFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPV 1102
Query: 653 RLSQSPVPSSGLLSPGGRGPQGALQSPSAQKRGLSPS-PSPASKSKKRPL----FGSPSP 707
+ + L + P + A +G+S P S+ K P+ G P P
Sbjct: 1103 LPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLP 1162
Query: 708 AE-KTPHPGPGLRVSGEQSLAWGLGGPSQS 736
+ K P G V EQ G GP +S
Sbjct: 1163 MDPKKLAPFSG--VKQEQLSPRGQAGPPES 1190
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 54.3 bits (129), Expect = 4e-07
Identities = 45/142 (31%), Positives = 61/142 (42%), Gaps = 17/142 (11%)
Query: 256 GLWQAMREWQHTSNFDRMIFYEMAEKFLEFEA-EEEMQIQKSQWMKGPQSLPPPAPPRLE 314
G+ +A + + TS + Y+ EK EA + E++ Q + PPP PP
Sbjct: 240 GISEAQLKDRETSK----VIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPH 295
Query: 315 PRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLP 374
GPP P + P +APTA PPP P RP+ +PPP P N P
Sbjct: 296 NSGPPPPPARGRGA--PPPPPSRAPTAAPPPPPPSRPS---VAVPPPPP------NRMYP 344
Query: 375 PPRPQRPAET-KVPEEIPPEVV 395
PP P P+ P PP V+
Sbjct: 345 PPPPALPSSAPSGPPPPPPSVL 366
Score = 52.0 bits (123), Expect = 2e-06
Identities = 32/98 (32%), Positives = 37/98 (37%), Gaps = 12/98 (12%)
Query: 301 GPQSLPPPA------PPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAET 354
GP PPP PP RG P P + P P P P+ +PPP P R
Sbjct: 286 GPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNR---- 341
Query: 355 KAHLPPPRPQRPAETNAHLPPPRPQRPAETKVPEEIPP 392
PPP P P+ + PPP P V PP
Sbjct: 342 --MYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPP 377
Score = 39.3 bits (90), Expect = 0.014
Identities = 26/69 (37%), Positives = 30/69 (43%), Gaps = 14/69 (20%)
Query: 306 PPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQR 365
PPPA P P GPP P V GP AP PPP P P PPP P
Sbjct: 346 PPPALPSSAPSGPPPPPPSVLGV------GPVAPPP--PPPPPPPPG------PPPPPGL 391
Query: 366 PAETNAHLP 374
P++ + +P
Sbjct: 392 PSDGDHQVP 400
Score = 38.5 bits (88), Expect = 0.023
Identities = 29/93 (31%), Positives = 35/93 (37%), Gaps = 13/93 (13%)
Query: 302 PQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPP 361
P P APP PP P + V +P P P PPP P P+ + PPP
Sbjct: 314 PSRAPTAAPP------PPPPS--RPSVAVP----PPPPNRMYPPPPPALPSSAPSGPPPP 361
Query: 362 RPQ-RPAETNAHLPPPRPQRPAETKVPEEIPPE 393
P A PPP P P P +P +
Sbjct: 362 PPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSD 394
Score = 33.9 bits (76), Expect = 0.57
Identities = 38/144 (26%), Positives = 49/144 (34%), Gaps = 30/144 (20%)
Query: 31 ATPAPGPAHRPPLVTAVVPPAGPLVLSAFPSTPLVAGQDGRGPSGAGASNVFVQMRTEVG 90
A P P P+ P PP P ++ P P G+ P + A T
Sbjct: 276 APPPPPPSRGGP------PPPPPPPHNSGPPPPPARGRGAPPPPPSRAP-------TAAP 322
Query: 91 PVKPPQAQTLILTQAPLVWQAPGTLCGGVMCPPPLLLAAAP-GVPVTSAQVVGGTQACEG 149
P PP ++ + P P PPP L ++AP G P V+G
Sbjct: 323 PPPPPSRPSVAVPPPPPNRMYPP--------PPPALPSSAPSGPPPPPPSVLGVGPVA-- 372
Query: 150 GWSHGLPLPPPPPAAQVAPIVSPG 173
P PPPPP P PG
Sbjct: 373 ------PPPPPPPPPPPGPPPPPG 390
Score = 31.6 bits (70), Expect = 2.8
Identities = 22/73 (30%), Positives = 26/73 (35%), Gaps = 4/73 (5%)
Query: 122 PPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPP----PPAAQVAPIVSPGNARP 177
PPP AP P + A S +P PPP PP P +P P
Sbjct: 301 PPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPP 360
Query: 178 WPQGAHGEGSLAP 190
P G G +AP
Sbjct: 361 PPPSVLGVGPVAP 373
Score = 30.8 bits (68), Expect = 4.9
Identities = 18/55 (32%), Positives = 24/55 (43%), Gaps = 1/55 (1%)
Query: 142 GGTQACEGGWSHGLPLPPPPP-AAQVAPIVSPGNARPWPQGAHGEGSLAPSQAKA 195
GG +A + P PPPP P P N+ P P A G G+ P ++A
Sbjct: 263 GGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRA 317
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 53.5 bits (127), Expect = 7e-07
Identities = 43/162 (26%), Positives = 66/162 (40%), Gaps = 23/162 (14%)
Query: 247 RKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQSLP 306
R+ + +E L + +E Q +R+ + E E +E+++ ++ +W + +
Sbjct: 212 RQERLERQERLDRERQERQERERLERL-----ERERQERERQEQLEREQLEWERERRISS 266
Query: 307 PPAPPRLEP----------RGPPAPEVVKQPVYLPSKDG----PKAPTACLPPPRPQRPA 352
AP +E P + QP PS+ G P AP PPP P PA
Sbjct: 267 AAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPP--PPPLPPGPA 324
Query: 353 ETKAHLPPPR--PQRPAETNAHLPPPRPQRPAETKVPEEIPP 392
+ LPPP P P + PPP P P +VP PP
Sbjct: 325 QASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPP 366
Score = 34.3 bits (77), Expect = 0.44
Identities = 27/77 (35%), Positives = 29/77 (37%), Gaps = 34/77 (44%)
Query: 306 PPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQR 365
PPP PP PP P LPS P P PPP P + +PPP P
Sbjct: 332 PPPGPP------PPPP--------LPSTGPPPPPP---PPPLPNQ-------VPPPPP-- 365
Query: 366 PAETNAHLPPPRPQRPA 382
PPP P PA
Sbjct: 366 --------PPPAPPLPA 374
Score = 30.0 bits (66), Expect = 8.3
Identities = 22/60 (36%), Positives = 25/60 (41%), Gaps = 11/60 (18%)
Query: 294 QKSQWMKGPQSLPPPAP-PRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPA 352
Q S + P PPP P P P PP P LP++ P P PPP P PA
Sbjct: 325 QASVALPPPPGPPPPPPLPSTGPPPPPPPPP------LPNQVPPPPP----PPPAPPLPA 374
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 53.5 bits (127), Expect = 7e-07
Identities = 43/162 (26%), Positives = 66/162 (40%), Gaps = 23/162 (14%)
Query: 247 RKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQSLP 306
R+ + +E L + +E Q +R+ + E E +E+++ ++ +W + +
Sbjct: 212 RQERLERQERLDRERQERQERERLERL-----ERERQERERQEQLEREQLEWERERRISS 266
Query: 307 PPAPPRLEP----------RGPPAPEVVKQPVYLPSKDG----PKAPTACLPPPRPQRPA 352
AP +E P + QP PS+ G P AP PPP P PA
Sbjct: 267 AAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPP--PPPLPPGPA 324
Query: 353 ETKAHLPPPR--PQRPAETNAHLPPPRPQRPAETKVPEEIPP 392
+ LPPP P P + PPP P P +VP PP
Sbjct: 325 QASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPP 366
Score = 34.3 bits (77), Expect = 0.44
Identities = 27/77 (35%), Positives = 29/77 (37%), Gaps = 34/77 (44%)
Query: 306 PPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQR 365
PPP PP PP P LPS P P PPP P + +PPP P
Sbjct: 332 PPPGPP------PPPP--------LPSTGPPPPPP---PPPLPNQ-------VPPPPP-- 365
Query: 366 PAETNAHLPPPRPQRPA 382
PPP P PA
Sbjct: 366 --------PPPAPPLPA 374
Score = 30.0 bits (66), Expect = 8.3
Identities = 22/60 (36%), Positives = 25/60 (41%), Gaps = 11/60 (18%)
Query: 294 QKSQWMKGPQSLPPPAP-PRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPA 352
Q S + P PPP P P P PP P LP++ P P PPP P PA
Sbjct: 325 QASVALPPPPGPPPPPPLPSTGPPPPPPPPP------LPNQVPPPPP----PPPAPPLPA 374
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 53.5 bits (127), Expect = 7e-07
Identities = 85/372 (22%), Positives = 121/372 (32%), Gaps = 62/372 (16%)
Query: 35 PGPAHRPPLVTAVVPPAG---PLVLSAFPSTPLVAGQDGRGPSGAGASNVFVQMRTEVGP 91
P RP A +PP P V A TPL+ P A V ++ P
Sbjct: 867 PQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQ-----PPMAQPPQVLLEDEEPPAP 921
Query: 92 VKPPQAQTLILTQAPLVWQAPGTLCGGVMC----PPPLLLAAAPGVPVTSAQVVGGTQAC 147
L L Q V Q P L V PPPL P P S Q Q
Sbjct: 922 PLTSMQMQLYLQQLQKV-QPPTPLLPSVKVQSQPPPPL-----PPPPHPSVQ----QQLQ 971
Query: 148 EGGWSHGLPLPPPPPAAQVAPIVSPGNARPWPQGAH------GEGSLAPSQAKAR---PD 198
+ P P PPP Q P P + +P H +G P + P
Sbjct: 972 QQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPP 1031
Query: 199 DSCKPKSVYENFRLWQHYK--PLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG 256
KP+ V ++ +H+K P + HL ++P + + +SL + P +
Sbjct: 1032 QPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQP 1091
Query: 257 LWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQSLPPPAPPRLEPR 316
Q +R + + + K + + P P P L P
Sbjct: 1092 KKQELRA-------------------ASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPE 1132
Query: 317 GPPAPEVVKQPVYLPSKDGPKAPTACLP---PPRPQRPAETKAHLPPPRPQRPAETNAHL 373
P PE +K PV+LP + K P PP P PP P + +
Sbjct: 1133 PPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAP-------PPGAPDKDKQKQEPK 1185
Query: 374 PPPRPQRPAETK 385
P P++ + K
Sbjct: 1186 TPVAPKKDLKIK 1197
Score = 50.4 bits (119), Expect = 6e-06
Identities = 33/92 (35%), Positives = 46/92 (50%), Gaps = 21/92 (22%)
Query: 306 PPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQ- 364
PPP PP PP P V +Q + P P PPP+PQ P + + H PPPRP
Sbjct: 955 PPPLPP------PPHPSVQQQ-----LQQQPPPP----PPPQPQPPPQQQ-HQPPPRPVH 998
Query: 365 -RPAETNAHL---PPPRPQRPAETKVPEEIPP 392
+P + + H+ PPP+ Q+P ++ PP
Sbjct: 999 LQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPP 1030
Score = 41.6 bits (96), Expect = 0.003
Identities = 36/136 (26%), Positives = 48/136 (35%), Gaps = 13/136 (9%)
Query: 294 QKSQWMKGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAE 353
Q+ Q P PP PP+ +P PP P+ +QP P P P P + P
Sbjct: 744 QQMQQAPAPVPQQPPPPPQ-QPPPPPPPQQQQQPP--PPPPPPSMPQQAAPAMKSSPPPF 800
Query: 354 TKAHLPPPRPQRPAE--------TNAHLPPPRPQRPAETKVPEE--IPPEVVQEYVDIME 403
+P PQ P T L P+P+ P P E PP + Q V
Sbjct: 801 IATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPP 860
Query: 404 ELLGSHPGDTGEPEGQ 419
L + P P +
Sbjct: 861 ALHNALPQQPSRPSNR 876
Score = 40.8 bits (94), Expect = 0.005
Identities = 33/120 (27%), Positives = 46/120 (38%), Gaps = 9/120 (7%)
Query: 306 PPPAPPR---LEPRGPPAPEV--VKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPP 360
PP A P LE PPAP + ++ +YL + PT LP + Q PP
Sbjct: 903 PPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLP-PP 961
Query: 361 PRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQR 420
P P + PPP P +P + PP V + +H P+GQ+
Sbjct: 962 PHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPP---PRPVHLQPMQFSTHIQQPPPPQGQQ 1018
Score = 39.7 bits (91), Expect = 0.010
Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 7/90 (7%)
Query: 344 PPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVP--EEIPPEVVQEYVDI 401
P P PQ+P PPP P P + PPP P + P + PP + V +
Sbjct: 750 PAPVPQQPPPPPQQPPPPPP--PQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPV 807
Query: 402 MEELLGSHPGDTGEPEGQREKGKVEQPQEE 431
+E L PG +P G + + PQ E
Sbjct: 808 LEPQL---PGSVFDPIGHFTQPILHLPQPE 834
Score = 38.5 bits (88), Expect = 0.023
Identities = 25/85 (29%), Positives = 34/85 (40%), Gaps = 12/85 (14%)
Query: 302 PQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPP 361
P PPP PP+ +P PAP+ P + P A P + ++ + KA P
Sbjct: 246 PLQTPPPVPPQPQPPPAPAPQ--------PVQSHPPIIAATPQPVKTKKGVKRKADTTTP 297
Query: 362 RPQRPAETNAHLPPPRPQRPAETKV 386
P H PP P P TK+
Sbjct: 298 TTIDP----IHEPPSLPPEPKTTKL 318
Score = 35.8 bits (81), Expect = 0.15
Identities = 128/564 (22%), Positives = 181/564 (32%), Gaps = 114/564 (20%)
Query: 28 LPFATPAPGPAHRPPLVT--AVVPPAGPLVLSAFPSTPLVAGQDGRGPSGAGASNVFVQM 85
LP P P PP + AVV P P + +A P P PS A+
Sbjct: 835 LPPHLPQPPEHSTPPHLNQHAVVSP--PALHNALPQQP-------SRPSNRAAA------ 879
Query: 86 RTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVMCPPPLLLAA---APGVPVTSAQVVG 142
P +PP A + LTQ PL+ Q P M PP +L P P+TS Q+
Sbjct: 880 -LPPKPARPP-AVSPALTQTPLLPQPP-------MAQPPQVLLEDEEPPAPPLTSMQMQL 930
Query: 143 GTQACEGGW-------------SHGLPLPPPPPAA------QVAPIVSPGNARPWPQGAH 183
Q + PLPPPP + Q P P +P PQ H
Sbjct: 931 YLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQH 990
Query: 184 GEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLA-RRHLPQSPDTEALSCFLIPVLR 242
Q RP H +P+ H+ Q P + P +
Sbjct: 991 --------QPPPRP----------------VHLQPMQFSTHIQQPPPPQGQQPPHPPPGQ 1026
Query: 243 SLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGP 302
+P Q + + H+ + Y EA + I Q M
Sbjct: 1027 QPPPPQPAKP------QQVIQHHHSPRHHKSDPYSTGHLR---EAPSPLMIHSPQ-MSQF 1076
Query: 303 QSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPR 362
QSL +PP+ + P K +A + P P E K H P R
Sbjct: 1077 QSLTHQSPPQQNVQ--------------PKKQELRAASVVQPQPLVV-VKEEKIHSPIIR 1121
Query: 363 PQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQREK 422
+ + L P P+ P K P +P + VD+ ++ P P G +K
Sbjct: 1122 SE---PFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVI-RPPEQNAPPPGAPDK 1177
Query: 423 GKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELL--SPDPQMDFLA 480
K +Q E P I + S V K HP S D F
Sbjct: 1178 DKQKQ---EPKTPVAPKKDLKIKNMGSWASLVQK-----HPTTPSSTAKSSSDSFEQFRR 1229
Query: 481 LSQELEQEEGLTLAQL--VEKRLLSLKEKGCGRAAPRHGTARLDSSPSEFAAGQEAAREV 538
++E E+ E AQ EK L+++ + + E QE ++
Sbjct: 1230 AAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQ 1289
Query: 539 PDPQQRVSVETSPPQTAAQDPQGQ 562
QQ+ + + AA PQ Q
Sbjct: 1290 RQEQQQQQQQQAAAVAAAATPQAQ 1313
Score = 33.1 bits (74), Expect = 0.98
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 7/88 (7%)
Query: 311 PRLEPRGPPAPEVVKQP-VYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQRPAET 369
P L P P PE P + + P A LP +P RP+ A LPP + PA +
Sbjct: 833 PELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQ-QPSRPSNRAAALPPKPARPPAVS 891
Query: 370 NA-----HLPPPRPQRPAETKVPEEIPP 392
A LP P +P + + +E PP
Sbjct: 892 PALTQTPLLPQPPMAQPPQVLLEDEEPP 919
Score = 32.3 bits (72), Expect = 1.7
Identities = 29/102 (28%), Positives = 38/102 (37%), Gaps = 21/102 (20%)
Query: 302 PQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPP 361
PQ PPP P P+++ Q + T PPP P +P PPP
Sbjct: 211 PQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQT---PPPVPPQPQ------PPP 261
Query: 362 RPQRPAETNAHLP----PPRP-------QRPAETKVPEEIPP 392
P P +H P P+P +R A+T P I P
Sbjct: 262 AP-APQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDP 302
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 52.0 bits (123), Expect = 2e-06
Identities = 89/394 (22%), Positives = 124/394 (31%), Gaps = 92/394 (23%)
Query: 21 SLSVFTALPFATPAPGPAHRPPL---------VTAVVPPAGPLVLSAFPSTPLVAGQDGR 71
+L ++ P ATP+P P+ + A +PP+ PL +TPL
Sbjct: 295 ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPL------ATPLPLAP--- 345
Query: 72 GPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVMCPPPLLLAAAP 131
PS P PP QTL A QAP ++ M PP L P
Sbjct: 346 -PS----------------PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPP-SLQTIP 387
Query: 132 GVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGNARPWPQGAHGEGSLAPS 191
+ V + QA PP P A + + P Q H +++P
Sbjct: 388 PIQVPHSLTSPSLQA------------PPSPLALSSLQATTSLGSPTLQATHSFLTMSPR 435
Query: 192 QAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQ---------SPDTEALSCFLIPVLR 242
Q +A +P S + Q PL+ P SP + L+ + L
Sbjct: 436 QTQASLTSPSRPASTPPDSPPLQ--APLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493
Query: 243 SLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGP 302
SLA P L + + E + + P
Sbjct: 494 SLASHSPQAPLSSLIMPPL--------------------------ETQSSLAPPSLQTPP 527
Query: 303 QSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTAC----LPPPRPQRPAETKAHL 358
SL P L PP + P+ P + P P C P P P ET + +
Sbjct: 528 ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI 587
Query: 359 PPPRPQRPAETNAHLPPPRPQRPAETKVPEEIPP 392
P PQ P A PP P+ P PP
Sbjct: 588 ATPPPQAPP---ALASPPLQGLPSPPLSPLATPP 618
Score = 48.1 bits (113), Expect = 3e-05
Identities = 31/93 (33%), Positives = 39/93 (41%), Gaps = 6/93 (6%)
Query: 306 PPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPK--APTACLPPPRPQRPAETKAHLPPPRP 363
PPP+PP P PPA V PS+ P AP +PP P P + + PPP+
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726
Query: 364 QRP-AETNAHLPPPRPQRP---AETKVPEEIPP 392
P A +PP P P P +PP
Sbjct: 727 PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759
Score = 47.8 bits (112), Expect = 4e-05
Identities = 90/381 (23%), Positives = 124/381 (32%), Gaps = 46/381 (12%)
Query: 12 PGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFPSTPLVAGQDGR 71
P T P T S+ T P A PA PPL PP PL + P +A +
Sbjct: 575 PLTTPPPETPSSIATPPPQAPPALAS---PPLQGLPSPPLSPLATPPPQAPPXLALPPLQ 631
Query: 72 GPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVMCPPPLLLAAAP 131
P AS + T + P A + L QAP + P + PP + P
Sbjct: 632 APPSPPASPPLSPLATP--SPQAPNALAVHLLQAP--FSPPPS-------PPVQAPFSPP 680
Query: 132 GVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGNARPWPQGAHGEGSLAPS 191
P S +QA + L +PP PPA+ P +SP +A P PQ LA
Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS---PPMSP-SATPPPQAPP---PLAAP 733
Query: 192 QAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTM 251
+ P P + + PL Q P + S + P+ + + P +
Sbjct: 734 PLQVPPSPPASPP-MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792
Query: 252 TLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQSLPPPAPP 311
+ F + S M + PP APP
Sbjct: 793 ATPP-------------------LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 833
Query: 312 RLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLP--PPRPQRPAET 369
L P +V P P+ P+ P P P T A P PP P R +
Sbjct: 834 VL---AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 890
Query: 370 NAHLPPPRPQRPAETKVPEEI 390
P + T PEE+
Sbjct: 891 TLSGPDLAGHSSSATSTPEEL 911
Score = 45.4 bits (106), Expect = 2e-04
Identities = 97/401 (24%), Positives = 136/401 (33%), Gaps = 65/401 (16%)
Query: 29 PFATPAPGPAHRPPLVTAVVPPAGPLVLSAFPSTPLVAGQD--GRGPSGAGASNVFVQMR 86
P P PA PPL T++ P PL S PL A P +S + +
Sbjct: 456 PLQAPLSLPAS-PPLQTSLSPAVSPLS-SPLTIHPLQALSSLASHSPQAPLSSLIMPPLE 513
Query: 87 TEVGPVKPPQAQT--LILTQAPLVWQAPGTLCGGVMCPPPLLLAAAPGVPVTSAQVVGGT 144
T+ + PP QT LT PL P + PPPL A+AP +T+ + T
Sbjct: 514 TQ-SSLAPPSLQTPPASLTTPPLE-NLPS------LAPPPLQTASAP---LTTPHLE--T 560
Query: 145 QACEGGWSHGLP-----LPPPPPAAQVA---PIVSPGNARPWPQGAHGE--GSLAPSQAK 194
C P PPP + +A P P A P QG LA +
Sbjct: 561 PPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQ 620
Query: 195 ARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLE 254
A P + P + PLA +P +A + + +L++ P+ ++
Sbjct: 621 APPXLALPPLQAPPSPPASPPLSPLA------TPSPQAPNALAVHLLQAPFSPPPSPPVQ 674
Query: 255 EGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQSLPPPAPPRLE 314
F A + A Q S + P PP+PP
Sbjct: 675 AP------------------FSPPASPPVSPSATPPSQAPPS--LAAPPLQVPPSPPASP 714
Query: 315 PRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPR-PQRPAETNAHL 373
P P A + P L AP +PP P P + + PPPR P A +
Sbjct: 715 PMSPSATPPPQAPPPL------AAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQV 768
Query: 374 PPPRP---QRPAETKVPEEIPPEVVQEYVDIMEELLGSHPG 411
PP P K P + PP + + + S PG
Sbjct: 769 PPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPG 809
Score = 42.7 bits (99), Expect = 0.001
Identities = 84/346 (24%), Positives = 105/346 (30%), Gaps = 53/346 (15%)
Query: 33 PAPGPAHRPPLVTAVVPPAGPLVLSAFP--STPLVAGQDGRGPSGAGASNVFVQMRTEVG 90
PAP P PP PP P ++ P + P +A +G S +
Sbjct: 564 PAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPL--------- 614
Query: 91 PVKPPQAQTLILTQAPLVWQAPGTLCGGVMCPPPLLLAAAPGVPVTSAQVVGGTQACEGG 150
PPQA L PL QAP + PPL A P +A V QA
Sbjct: 615 ATPPPQAPPX-LALPPL--QAPPS----PPASPPLSPLATPSPQAPNALAVHLLQAPFS- 666
Query: 151 WSHGLPLPPPPPAAQVAPIVSPGNARPWPQGAHGEGSLAPSQAKARPDDSCKPKSVYENF 210
P P PP A +P SP + + SLA + P P
Sbjct: 667 -----PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 721
Query: 211 RLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWQAMREWQHTSNF 270
Q PLA L Q P + S + P R P +
Sbjct: 722 PPPQAPPPLAAPPL-QVPPSPPASPPMSPSATPPPRVPPLL------------------- 761
Query: 271 DRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQSLPPP-APPRLEPRGPPAPEVVKQPVY 329
A L+ + S K P PP A P L+ P Q +
Sbjct: 762 --------AAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 813
Query: 330 LPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPP 375
PS P +P A PP P A +PP P P PP
Sbjct: 814 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 859
Score = 40.8 bits (94), Expect = 0.005
Identities = 36/113 (31%), Positives = 44/113 (38%), Gaps = 22/113 (19%)
Query: 300 KGPQSLPPP--APPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPR---------- 347
KG Q+L PP PPR + P + P+ PS G KA +PPP
Sbjct: 275 KGLQALRPPQVTPPRKDA-APALGPLSSSPLATPSPSGTKARP--VPPPDNAATPLPATL 331
Query: 348 -PQRPAETKAHLPPPRPQRPAETNAHLP-----PPRPQRPAETKVPEEIPPEV 394
P P T L PP P P LP PP P+ T P + PP +
Sbjct: 332 PPSPPLATPLPLAPPSPSAPPSLQT-LPSPPATPPSQAPPSMTTPPMQAPPSL 383
Score = 39.7 bits (91), Expect = 0.010
Identities = 57/204 (27%), Positives = 75/204 (36%), Gaps = 26/204 (12%)
Query: 6 AYPVLG-PGVTVNPGTSLSVFTALPFATPAPGP--AHRPPLVTAVVPPAGPLVLSAFPST 62
A PVL P + V P S P P PGP + P +T + P P S PS+
Sbjct: 831 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 890
Query: 63 PLVAGQDGRGPSGAGASNVFVQMRTEVGP------VKPPQAQTLILTQAPLVW-QAPGTL 115
L +G D G S + S + GP PP A+ + P W + P
Sbjct: 891 TL-SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE--LAACHPAAWSRGPA-- 945
Query: 116 CGGVMCPPPLLLAAAPGVPVTSAQVVGGTQA---CEGGWSHGLPLPPPPPAAQVAPIVSP 172
PPL APG P+ G A C + G P P A + P SP
Sbjct: 946 -------PPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA-LDPGPSP 997
Query: 173 GNARPWPQGAHGEGSLAPSQAKAR 196
G + G G+ + S +AR
Sbjct: 998 GTSGGKAAAGAGAGASSRSPKQAR 1021
Score = 37.7 bits (86), Expect = 0.040
Identities = 102/489 (20%), Positives = 150/489 (30%), Gaps = 81/489 (16%)
Query: 302 PQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKA-HLPP 360
P + P P+ + P PP P LP P A L PP P P + PP
Sbjct: 303 PLATPSPSGTKARPVPPPDNAATPLPATLPPSP-PLATPLPLAPPSPSAPPSLQTLPSPP 361
Query: 361 PRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDI-----------------ME 403
P A + PP + +T P ++P + +
Sbjct: 362 ATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSP 421
Query: 404 ELLGSHPGDTGEPEGQREKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHP 463
L +H T P ++ + + P D L L + T + + P
Sbjct: 422 TLQATHSFLTMSP--RQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSP 479
Query: 464 ----------RFLEELLSPDPQMDFLAL-SQELEQEEGLTLAQLVE----------KRLL 502
+ L L S PQ +L LE + L L + L
Sbjct: 480 LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP 539
Query: 503 SLKEKGCGRAAPRHGTARLDSSPSEFAAGQEAARE---VPDPQQRVSVETSPPQT--AAQ 557
SL A+ T L++ P +A P P+ S+ T PPQ A
Sbjct: 540 SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA 599
Query: 558 DPQGQG-------RVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDHRPTCPGLGTKD 610
P QG + T ++ L Q P A P SP P P
Sbjct: 600 SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 659
Query: 611 ALGLPGESPVK----------ESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQSPVP 660
L P P S ++ ++ ++ P + P ++ SP P
Sbjct: 660 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL-------AAPPLQVPPSP-P 711
Query: 661 SSGLLSPGGRGPQGA--------LQSPSAQKRGLSPSPSPASKSKKRPLFGSPSPAEKTP 712
+S +SP P A LQ P + SPS + PL +P P + P
Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAP-PLQVPP 770
Query: 713 HPGPGLRVS 721
P L +S
Sbjct: 771 SPPASLPMS 779
Score = 36.6 bits (83), Expect = 0.089
Identities = 51/198 (25%), Positives = 66/198 (33%), Gaps = 31/198 (15%)
Query: 6 AYPVLGPGVTVNPGTSLSVFTAL---PFATPAPGPAHRPPLVTAVVPPAGPLVLSAFPST 62
A P L P T +P ++ L PF+ P P P + P PP P +
Sbjct: 638 ASPPLSPLATPSPQAPNALAVHLLQAPFSPP-PSPPVQAPFSPPASPPVSPSATPPSQAP 696
Query: 63 PLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVMCP 122
P +A + P AS T PP A AP + P M P
Sbjct: 697 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA-------APPLQVPPSPPASPPMSP 749
Query: 123 --------PPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGN 174
PPLL A VP + + + PL PPP A A P
Sbjct: 750 SATPPPRVPPLLAAPPLQVPPSPPASLPMS-----------PLAKPPPQAPPALATPPLQ 798
Query: 175 ARPWPQGAH-GEGSLAPS 191
A P P + G+ +PS
Sbjct: 799 ALPSPPASFPGQAPFSPS 816
Score = 35.4 bits (80), Expect = 0.20
Identities = 32/106 (30%), Positives = 39/106 (36%), Gaps = 22/106 (20%)
Query: 307 PPAPPRLEPRGPPAPEV----VKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPP-- 360
PPA P + P P P V P+ +P P + L P PQ P PP
Sbjct: 741 PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT--PPLQ 798
Query: 361 --PRP------QRPAETNAHLP-----PPRPQRPAETKVP-EEIPP 392
P P Q P +A LP P PQ P P ++PP
Sbjct: 799 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 844
Score = 34.7 bits (78), Expect = 0.34
Identities = 56/213 (26%), Positives = 67/213 (31%), Gaps = 31/213 (14%)
Query: 8 PVLGPGVTVNPGTSLSVFTALPFATP---APGPAHRPPLVTAVVPPAGPLVLSAFPSTPL 64
P P + P L P ATP AP PPL PPA P P +PL
Sbjct: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP------PLSPL 645
Query: 65 VAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVW-------QAPGTLCG 117
P A V + P PP +P V QAP +L
Sbjct: 646 ATPS----PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 701
Query: 118 GVMCPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPPA-------AQVAPIV 170
+ PP + P P S QA + L +PP PPA A P V
Sbjct: 702 PPLQVPP----SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757
Query: 171 SPGNARPWPQGAHGEGSLAPSQAKARPDDSCKP 203
P A P Q + P A+P P
Sbjct: 758 PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPP 790
Score = 31.2 bits (69), Expect = 3.7
Identities = 51/232 (21%), Positives = 74/232 (31%), Gaps = 27/232 (11%)
Query: 485 LEQEEGLTLAQLVEKRLLSLKEKGCGR--AAPRHGTARLDSSPSEFAAGQEAAREVPDPQ 542
+ EE + + E S G R + P GT + AAG E P P
Sbjct: 136 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 195
Query: 543 QRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDHRPT 602
R T P+ + A P+ G Q P +++ ++ P +
Sbjct: 196 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ-RPASRSLSSSATPL----S 250
Query: 603 CPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQSPVPSS 662
P A G P +P S KG LRP +++ ++
Sbjct: 251 SPARSGPSARGTP-RAPAHPSQPKPKGLQA----------------LRPPQVTPPRKDAA 293
Query: 663 GLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKKRPLFGSPSPAEKTPHP 714
L P P L +PS P P P + + P PSP TP P
Sbjct: 294 PALGPLSSSP---LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP 342
>gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo
sapiens]
Length = 218
Score = 51.6 bits (122), Expect = 3e-06
Identities = 36/86 (41%), Positives = 40/86 (46%), Gaps = 24/86 (27%)
Query: 301 GPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPP 360
G S PPP PPR PR P K P LP P P LPPPRP +P LPP
Sbjct: 20 GLWSPPPPLPPRKPPRPP------KPPRPLP----PNPPRPPLPPPRPPKPP-----LPP 64
Query: 361 PRPQRPAETNAHLPPPRPQRPAETKV 386
PRP + PP P A++KV
Sbjct: 65 PRPPK---------PPSPLGLAQSKV 81
Score = 40.0 bits (92), Expect = 0.008
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 9/56 (16%)
Query: 338 APTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPE 393
+P LPP +P RP + LPP P+ P LPPPRP +P +P PP+
Sbjct: 23 SPPPPLPPRKPPRPPKPPRPLPPNPPRPP------LPPPRPPKP---PLPPPRPPK 69
>gi|239747993 PREDICTED: hypothetical protein XP_002346504 [Homo
sapiens]
Length = 218
Score = 51.6 bits (122), Expect = 3e-06
Identities = 36/86 (41%), Positives = 40/86 (46%), Gaps = 24/86 (27%)
Query: 301 GPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPP 360
G S PPP PPR PR P K P LP P P LPPPRP +P LPP
Sbjct: 20 GLWSPPPPLPPRKPPRPP------KPPRPLP----PNPPRPPLPPPRPPKPP-----LPP 64
Query: 361 PRPQRPAETNAHLPPPRPQRPAETKV 386
PRP + PP P A++KV
Sbjct: 65 PRPPK---------PPSPLGLAQSKV 81
Score = 40.0 bits (92), Expect = 0.008
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 9/56 (16%)
Query: 338 APTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPE 393
+P LPP +P RP + LPP P+ P LPPPRP +P +P PP+
Sbjct: 23 SPPPPLPPRKPPRPPKPPRPLPPNPPRPP------LPPPRPPKP---PLPPPRPPK 69
>gi|239741891 PREDICTED: hypothetical protein XP_002342316 [Homo
sapiens]
Length = 218
Score = 51.6 bits (122), Expect = 3e-06
Identities = 36/86 (41%), Positives = 40/86 (46%), Gaps = 24/86 (27%)
Query: 301 GPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPP 360
G S PPP PPR PR P K P LP P P LPPPRP +P LPP
Sbjct: 20 GLWSPPPPLPPRKPPRPP------KPPRPLP----PNPPRPPLPPPRPPKPP-----LPP 64
Query: 361 PRPQRPAETNAHLPPPRPQRPAETKV 386
PRP + PP P A++KV
Sbjct: 65 PRPPK---------PPSPLGLAQSKV 81
Score = 40.0 bits (92), Expect = 0.008
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 9/56 (16%)
Query: 338 APTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPE 393
+P LPP +P RP + LPP P+ P LPPPRP +P +P PP+
Sbjct: 23 SPPPPLPPRKPPRPPKPPRPLPPNPPRPP------LPPPRPPKP---PLPPPRPPK 69
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 51.2 bits (121), Expect = 3e-06
Identities = 34/99 (34%), Positives = 42/99 (42%), Gaps = 11/99 (11%)
Query: 299 MKGPQSLP-----PPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAE 353
+ P SLP P PP P P + + V +PS TA PPP P
Sbjct: 618 ISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPP----PLP 673
Query: 354 TKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVPEEIPP 392
A +PPP P P +A +PPP P P E +P PP
Sbjct: 674 GSARIPPPPPPLPG--SAGIPPPPPPLPGEAGMPPPPPP 710
Score = 51.2 bits (121), Expect = 3e-06
Identities = 33/93 (35%), Positives = 44/93 (47%), Gaps = 6/93 (6%)
Query: 299 MKGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHL 358
+ G ++PPP PP E G P+P + +P P +A +PPP P P A +
Sbjct: 636 LSGDATIPPP-PPLPEGVGIPSPSSLPGGTAIPPPP-PLPGSARIPPPPPPLPGS--AGI 691
Query: 359 PPPRPQRPAETNAHLPPPRPQRPAETKVPEEIP 391
PPP P P E A +PPP P P +P P
Sbjct: 692 PPPPPPLPGE--AGMPPPPPPLPGGPGIPPPPP 722
Score = 44.7 bits (104), Expect = 3e-04
Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 5/90 (5%)
Query: 289 EEMQIQKSQWMKGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRP 348
E + I + G ++PPP P R PP P + +P P A +PPP P
Sbjct: 650 EGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPP 709
Query: 349 QRPAETKAHLPPPRPQRPAETNAHLPPPRP 378
P PPP P P +PPP P
Sbjct: 710 PLPGGPGIPPPPPFPGGPG-----IPPPPP 734
Score = 40.0 bits (92), Expect = 0.008
Identities = 31/111 (27%), Positives = 38/111 (34%), Gaps = 26/111 (23%)
Query: 301 GPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPP 360
G + PPP PP PP P + V + S TA PPP A PP
Sbjct: 594 GDSTTPPPPPPP-----PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPP--PP 646
Query: 361 PRPQ-------------------RPAETNAHLPPPRPQRPAETKVPEEIPP 392
P P+ P +A +PPP P P +P PP
Sbjct: 647 PLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPP 697
Score = 36.2 bits (82), Expect = 0.12
Identities = 37/137 (27%), Positives = 47/137 (34%), Gaps = 38/137 (27%)
Query: 33 PAPGPAHRPPLVTAVVPPAGPL----VLSAFPSTPLVAGQDGRGPSGAGASNVFVQMRTE 88
PAPG + PP PP PL +S+ PS P T
Sbjct: 591 PAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLP---------------------GGTA 629
Query: 89 VGPVKPPQAQTLILTQAPLV----WQAPGTLCGGVMCPPPLLLAAAPGVPVTSAQVVGGT 144
+ P P I PL +P +L GG PPP L + +P + G
Sbjct: 630 ISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPG-- 687
Query: 145 QACEGGWSHGLPLPPPP 161
S G+P PPPP
Sbjct: 688 -------SAGIPPPPPP 697
Score = 36.2 bits (82), Expect = 0.12
Identities = 42/169 (24%), Positives = 52/169 (30%), Gaps = 60/169 (35%)
Query: 8 PVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFPSTPLVAG 67
P L GV + +SL TA+P P PG A PP PP P P P + G
Sbjct: 646 PPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPP-----PPPPLPGSAGIPPPPPPLPG 700
Query: 68 QDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVMCPPPLLL 127
+ G P P L GG PPP
Sbjct: 701 EAGMPPP-------------------------------------PPPLPGGPGIPPPPPF 723
Query: 128 AAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPP---AAQVAPIVSPG 173
PG+P G+ +PPPPP AP++ G
Sbjct: 724 PGGPGIPPPPP---------------GMGMPPPPPFGFGVPAAPVLPFG 757
Score = 35.8 bits (81), Expect = 0.15
Identities = 31/110 (28%), Positives = 41/110 (37%), Gaps = 8/110 (7%)
Query: 277 EMAEKFLEFE-AEEEMQIQKSQWMKGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDG 335
E+A+ E E A++EM + + P S+P AP P P + P P
Sbjct: 538 EVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDST 597
Query: 336 PKAPTACLPPPRPQRPAETKAHLPPP-------RPQRPAETNAHLPPPRP 378
P PPP P P PP P P +A +PPP P
Sbjct: 598 TPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPP 647
Score = 33.9 bits (76), Expect = 0.57
Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 4/46 (8%)
Query: 336 PKAPTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRP 381
P P+ PP P P ++ +PPP PA ++ PPP P P
Sbjct: 565 PSVPSRAPVPPAPPLPGDSGTIIPPP----PAPGDSTTPPPPPPPP 606
Score = 33.5 bits (75), Expect = 0.75
Identities = 48/172 (27%), Positives = 57/172 (33%), Gaps = 40/172 (23%)
Query: 8 PVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFPSTPLVAG 67
P L GV ++ SL TA+ P G A PP PP PL G
Sbjct: 610 PPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPP------PP------------PLPEG 651
Query: 68 QDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVMCPPPLLL 127
PS T + P P I P PG+ G+ PPP L
Sbjct: 652 VGIPSPSSLPGG-------TAIPPPPPLPGSARIPPPPP---PLPGS--AGIPPPPPPLP 699
Query: 128 AAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGNARPWP 179
A G+P + GG G+P PPP P P PG P P
Sbjct: 700 GEA-GMPPPPPPLPGGP---------GIPPPPPFPGGPGIPPPPPGMGMPPP 741
Score = 32.7 bits (73), Expect = 1.3
Identities = 41/152 (26%), Positives = 54/152 (35%), Gaps = 30/152 (19%)
Query: 48 VPPAGPLVLSAFPSTPLVAGQDGR--GPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQA 105
VPP+ P P+ PL G G P A + P PP + ++
Sbjct: 563 VPPSVPSRAPVPPAPPL-PGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSP 621
Query: 106 PLV-----WQAPGTLCGGVMCPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPP 160
P + P L G PPP L G+P S+ + GGT +PPP
Sbjct: 622 PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSS-LPGGTA-----------IPPP 669
Query: 161 PPAAQVAPIVSPGNAR--PWPQGAHGEGSLAP 190
PP PG+AR P P G + P
Sbjct: 670 PPL--------PGSARIPPPPPPLPGSAGIPP 693
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 51.2 bits (121), Expect = 3e-06
Identities = 34/99 (34%), Positives = 42/99 (42%), Gaps = 11/99 (11%)
Query: 299 MKGPQSLP-----PPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAE 353
+ P SLP P PP P P + + V +PS TA PPP P
Sbjct: 627 ISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPP----PLP 682
Query: 354 TKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVPEEIPP 392
A +PPP P P +A +PPP P P E +P PP
Sbjct: 683 GSARIPPPPPPLPG--SAGIPPPPPPLPGEAGMPPPPPP 719
Score = 51.2 bits (121), Expect = 3e-06
Identities = 33/93 (35%), Positives = 44/93 (47%), Gaps = 6/93 (6%)
Query: 299 MKGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHL 358
+ G ++PPP PP E G P+P + +P P +A +PPP P P A +
Sbjct: 645 LSGDATIPPP-PPLPEGVGIPSPSSLPGGTAIPPPP-PLPGSARIPPPPPPLPGS--AGI 700
Query: 359 PPPRPQRPAETNAHLPPPRPQRPAETKVPEEIP 391
PPP P P E A +PPP P P +P P
Sbjct: 701 PPPPPPLPGE--AGMPPPPPPLPGGPGIPPPPP 731
Score = 44.7 bits (104), Expect = 3e-04
Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 5/90 (5%)
Query: 289 EEMQIQKSQWMKGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRP 348
E + I + G ++PPP P R PP P + +P P A +PPP P
Sbjct: 659 EGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPP 718
Query: 349 QRPAETKAHLPPPRPQRPAETNAHLPPPRP 378
P PPP P P +PPP P
Sbjct: 719 PLPGGPGIPPPPPFPGGPG-----IPPPPP 743
Score = 40.0 bits (92), Expect = 0.008
Identities = 31/111 (27%), Positives = 38/111 (34%), Gaps = 26/111 (23%)
Query: 301 GPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPP 360
G + PPP PP PP P + V + S TA PPP A PP
Sbjct: 603 GDSTTPPPPPPP-----PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPP--PP 655
Query: 361 PRPQ-------------------RPAETNAHLPPPRPQRPAETKVPEEIPP 392
P P+ P +A +PPP P P +P PP
Sbjct: 656 PLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPP 706
Score = 36.2 bits (82), Expect = 0.12
Identities = 37/137 (27%), Positives = 47/137 (34%), Gaps = 38/137 (27%)
Query: 33 PAPGPAHRPPLVTAVVPPAGPL----VLSAFPSTPLVAGQDGRGPSGAGASNVFVQMRTE 88
PAPG + PP PP PL +S+ PS P T
Sbjct: 600 PAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLP---------------------GGTA 638
Query: 89 VGPVKPPQAQTLILTQAPLV----WQAPGTLCGGVMCPPPLLLAAAPGVPVTSAQVVGGT 144
+ P P I PL +P +L GG PPP L + +P + G
Sbjct: 639 ISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPG-- 696
Query: 145 QACEGGWSHGLPLPPPP 161
S G+P PPPP
Sbjct: 697 -------SAGIPPPPPP 706
Score = 36.2 bits (82), Expect = 0.12
Identities = 42/169 (24%), Positives = 52/169 (30%), Gaps = 60/169 (35%)
Query: 8 PVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFPSTPLVAG 67
P L GV + +SL TA+P P PG A PP PP P P P + G
Sbjct: 655 PPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPP-----PPPPLPGSAGIPPPPPPLPG 709
Query: 68 QDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVMCPPPLLL 127
+ G P P L GG PPP
Sbjct: 710 EAGMPPP-------------------------------------PPPLPGGPGIPPPPPF 732
Query: 128 AAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPP---AAQVAPIVSPG 173
PG+P G+ +PPPPP AP++ G
Sbjct: 733 PGGPGIPPPPP---------------GMGMPPPPPFGFGVPAAPVLPFG 766
Score = 35.8 bits (81), Expect = 0.15
Identities = 31/110 (28%), Positives = 41/110 (37%), Gaps = 8/110 (7%)
Query: 277 EMAEKFLEFE-AEEEMQIQKSQWMKGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDG 335
E+A+ E E A++EM + + P S+P AP P P + P P
Sbjct: 547 EVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDST 606
Query: 336 PKAPTACLPPPRPQRPAETKAHLPPP-------RPQRPAETNAHLPPPRP 378
P PPP P P PP P P +A +PPP P
Sbjct: 607 TPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPP 656
Score = 33.9 bits (76), Expect = 0.57
Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 4/46 (8%)
Query: 336 PKAPTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRP 381
P P+ PP P P ++ +PPP PA ++ PPP P P
Sbjct: 574 PSVPSRAPVPPAPPLPGDSGTIIPPP----PAPGDSTTPPPPPPPP 615
Score = 33.5 bits (75), Expect = 0.75
Identities = 48/172 (27%), Positives = 57/172 (33%), Gaps = 40/172 (23%)
Query: 8 PVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFPSTPLVAG 67
P L GV ++ SL TA+ P G A PP PP PL G
Sbjct: 619 PPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPP------PP------------PLPEG 660
Query: 68 QDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVMCPPPLLL 127
PS T + P P I P PG+ G+ PPP L
Sbjct: 661 VGIPSPSSLPGG-------TAIPPPPPLPGSARIPPPPP---PLPGS--AGIPPPPPPLP 708
Query: 128 AAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGNARPWP 179
A G+P + GG G+P PPP P P PG P P
Sbjct: 709 GEA-GMPPPPPPLPGGP---------GIPPPPPFPGGPGIPPPPPGMGMPPP 750
Score = 32.7 bits (73), Expect = 1.3
Identities = 41/152 (26%), Positives = 54/152 (35%), Gaps = 30/152 (19%)
Query: 48 VPPAGPLVLSAFPSTPLVAGQDGR--GPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQA 105
VPP+ P P+ PL G G P A + P PP + ++
Sbjct: 572 VPPSVPSRAPVPPAPPL-PGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSP 630
Query: 106 PLV-----WQAPGTLCGGVMCPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPP 160
P + P L G PPP L G+P S+ + GGT +PPP
Sbjct: 631 PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSS-LPGGTA-----------IPPP 678
Query: 161 PPAAQVAPIVSPGNAR--PWPQGAHGEGSLAP 190
PP PG+AR P P G + P
Sbjct: 679 PPL--------PGSARIPPPPPPLPGSAGIPP 702
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 50.8 bits (120), Expect = 5e-06
Identities = 55/218 (25%), Positives = 88/218 (40%), Gaps = 33/218 (15%)
Query: 282 FLEFEAEEEMQIQKSQWMKGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTA 341
F+ ++ EE ++ S S+ P L P PP P P P+ GP PTA
Sbjct: 765 FVHYDKEEASDVEISLESDSDDSVVI-VPEGLPPLPPPPPSGATPPPIAPT--GP--PTA 819
Query: 342 CLPPPRPQRPAETKAHL----PPPRPQRPAETNAHLPPPRPQRPAETKVPEEIP----PE 393
P P + P E A PPP P P LPPP+ VPE P P
Sbjct: 820 SPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQ-------LVPEGTPGGGGPP 872
Query: 394 VVQEYVDIMEELLGSHPGDTGEPEGQREKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDF 453
++E + ++ + S + E E + E+ + E+ +EED + Y ++ +E+
Sbjct: 873 ALEEDLTVIN--INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEE- 929
Query: 454 VTKVEAVIHPRFLEELLSPDPQMDFLALSQELEQEEGL 491
F EE + +++ ++ E+EE L
Sbjct: 930 ----------EFEEEFEEEEGELEEEEEEEDEEEEEEL 957
Score = 48.9 bits (115), Expect = 2e-05
Identities = 74/297 (24%), Positives = 104/297 (35%), Gaps = 50/297 (16%)
Query: 300 KGPQSLPPP-----APPRLEPRGPPAPEVVKQPVYLPSKDGPK----APTACLPPPRPQR 350
+G LPPP PP + P GPP PV P+K+ P+ AP PPP P
Sbjct: 793 EGLPPLPPPPPSGATPPPIAPTGPPT---ASPPV--PAKEEPEELPAAPGPLPPPPPPPP 847
Query: 351 PAETKAHLPPPRPQRPAETNAHLPPP------------RPQRPAETKVPEEIPPEVVQEY 398
P LPPP+ PP + E + EE E +E
Sbjct: 848 PVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEE 907
Query: 399 VDIMEELLGSHP--------GDTGEPEGQREKGKVEQPQEEDGITSDPGLLSYIDKLCSQ 450
D EE + E E + E+G++E+ +EE+ + L D
Sbjct: 908 EDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGT 967
Query: 451 EDFVTKVEAVIHPRFLEELLSPDPQMDFLALSQELEQEEGLTLAQLVEKRLLSLKEKGCG 510
+ A P L P+ + E E E GL LL ++E G
Sbjct: 968 AGGEVEEGAPPPPTLPPALPPPESPPK---VQPEPEPEPGL---------LLEVEEPGTE 1015
Query: 511 --RAAPRHGTARLDSSPSEFAAGQEAAREV--PDPQQRVSVETSPPQTAAQDPQGQG 563
R A T ++ PS+ +E P PQ+ V E S P T ++ G
Sbjct: 1016 EERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDG 1072
Score = 43.9 bits (102), Expect = 6e-04
Identities = 33/117 (28%), Positives = 49/117 (41%), Gaps = 21/117 (17%)
Query: 302 PQSLPPP-APPRLEPRGPPAPEV---VKQPVYLPSKDGPKAPTAC---LPP--------- 345
P +LPPP +PP+++P P P + V++P + APT LP
Sbjct: 983 PPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGE 1042
Query: 346 -----PRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQE 397
P PQ E + PP + E + P P+ PAE ++ E E +QE
Sbjct: 1043 SPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQE 1099
Score = 38.5 bits (88), Expect = 0.023
Identities = 110/485 (22%), Positives = 162/485 (33%), Gaps = 64/485 (13%)
Query: 16 VNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPL-----VLSAFPSTPLVAGQDG 70
V P + S F A PF P P P+ +P AGP+ V SA P P A G
Sbjct: 651 VPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLG 710
Query: 71 RGPSGAGASNVFVQMRTEVGPVKPPQAQT----LILTQAPLVWQAPGTLCGGVMCPPPLL 126
G V V R GP L + P P GG + P +
Sbjct: 711 LSVPGL----VSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFV 766
Query: 127 LAAAPGVPVTSAQVVGGTQACEGGWSHGLP-LPPPPPAAQVAPIVS---PGNARPWPQGA 182
+ + GLP LPPPPP+ P ++ P A P P A
Sbjct: 767 HYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASP-PVPA 825
Query: 183 HGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLR 242
E P+ P P V L L P AL L +
Sbjct: 826 KEEPEELPAAPGPLPPPPPPPPPVPGPVTLPP--PQLVPEGTPGGGGPPALEEDLTVINI 883
Query: 243 SLARRKPTMTLEEGLWQAMRE-----WQHTSNFDRMIFYEMAEKFLEFEAE--------- 288
+ + + EE + E ++ + F E E+ EFE E
Sbjct: 884 NSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELE 943
Query: 289 ---EEMQIQKSQWMKGPQSLP-PPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLP 344
EE ++ + ++ + L A +E PP P + P LP P++P P
Sbjct: 944 EEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTL---PPALPP---PESPPKVQP 997
Query: 345 PPRPQRPAETKAHLPPPRPQRPAETNAHLPPP----------RPQRPAETKVPEEI---- 390
P P+ + P +R A+T L P + PA P+E+
Sbjct: 998 EPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEE 1057
Query: 391 ---PPEVVQEYVDIMEELLGSHPGDTGEPEGQREKGKVEQPQEEDGITSDPGLLSYIDKL 447
PP +++E + + + P E E + E + E QE++ + L +ID
Sbjct: 1058 PSAPPTLLEEETEDGSDKVQPPPETPAEEEMETET-EAEALQEKEQDDTAAMLADFID-- 1114
Query: 448 CSQED 452
C +D
Sbjct: 1115 CPPDD 1119
Score = 30.0 bits (66), Expect = 8.3
Identities = 23/81 (28%), Positives = 31/81 (38%), Gaps = 9/81 (11%)
Query: 304 SLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRP 363
+L P P L+P GP P P +P + P A PP P P + +P P
Sbjct: 629 ALTHPRVPPLQPMGPTCP----TPAPVPPPEAPSPFRA--PPFHPPGPMPSVGSMPSAGP 682
Query: 364 Q---RPAETNAHLPPPRPQRP 381
P + +P RP P
Sbjct: 683 MPSAGPMPSAGPVPSARPGPP 703
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 50.4 bits (119), Expect = 6e-06
Identities = 85/394 (21%), Positives = 146/394 (37%), Gaps = 69/394 (17%)
Query: 219 LARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEM 278
++++ +PQ P + +I V K + EE ++ A S+ + + +
Sbjct: 9209 VSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFA-------SHTEEEVSVTV 9261
Query: 279 AEKFLEFEAEEEMQIQKSQWMKGPQSLPP-------------PAPPRLEPRGPPAPEV-- 323
E E EE++ + S+ ++ P +P P P ++EP P PEV
Sbjct: 9262 PEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPK 9321
Query: 324 -----VKQPVYLPSKDG------PKAPTACLPPPRPQRPAETKAHLPP---PRPQRPAET 369
K+PV +P K+ P+ P +P + P K PP P Q+ T
Sbjct: 9322 KPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVT 9381
Query: 370 NAHL---------PPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQR 420
+ PPP + KVPEE P V EE + P P+
Sbjct: 9382 EEKITIVTQREESPPPAVPEIPKKKVPEERKP------VPRKEEEVPPPPKVPALPKKPV 9435
Query: 421 EKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVT----------KVEAVIHPRFLEELL 470
+ KV P P + ++ FV +VE H EE
Sbjct: 9436 PEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEW 9495
Query: 471 SPDPQMDFLALS----QELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPS 526
S + + +++S +E E+EE A++ E ++ E+ + R+++ P+
Sbjct: 9496 SYSEEEEGVSISVYREEEREEEEE---AEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPA 9552
Query: 527 EFAAGQEAAREVPDPQQRVSVETSPPQTAAQDPQ 560
E QE + V P+ +E PP + P+
Sbjct: 9553 EVTERQE-KKIVLKPKIPAKIEEPPPAKVPEAPK 9585
Score = 47.0 bits (110), Expect = 7e-05
Identities = 39/141 (27%), Positives = 56/141 (39%), Gaps = 12/141 (8%)
Query: 303 QSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTA---CLPPPRPQRPAET--KAH 357
+ +P PP+ E P PE K+ V P K P AP P P+ P E +
Sbjct: 10564 KKVPEAIPPKPESPPPEVPEAPKEVV--PEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKK 10621
Query: 358 LPPPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPE 417
+P P P++P +P E KVPE IPP+ ++ EE P + E
Sbjct: 10622 VPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEE-----PEEVALEE 10676
Query: 418 GQREKGKVEQPQEEDGITSDP 438
E + +P +T P
Sbjct: 10677 PPAEVVEEPEPAAPPQVTVPP 10697
Score = 46.2 bits (108), Expect = 1e-04
Identities = 58/244 (23%), Positives = 90/244 (36%), Gaps = 47/244 (19%)
Query: 156 PLPPPPPAAQVAPIVSPGNARPWPQGAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQH 215
P PPP + ++ +P P P A P + K K F+L
Sbjct: 10858 PEAPPPKEPEPEKVIEKPKLKPRP----------PPPPPAPPKEDVKEKI----FQL--- 10900
Query: 216 YKPLARRHLP---QSPDTEALSCFLIP-----VLRSLARRKPTMTLEEGLWQAMREWQHT 267
K + ++ +P Q P+ L+ +P V + L RKP E L +R+
Sbjct: 10901 -KAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPE- 10958
Query: 268 SNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQSLPPPAPPRLEPRGPPAPEVVKQP 327
E E +++ +K + +K P PP P +E P ++
Sbjct: 10959 ------------------EEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERK 11000
Query: 328 VYLPSKDGPKAPTACLP--PPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETK 385
+ P+K P LP P+P+ AE K PPP P A + P + AE K
Sbjct: 11001 IPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAK 11060
Query: 386 VPEE 389
P+E
Sbjct: 11061 APKE 11064
Score = 45.8 bits (107), Expect = 1e-04
Identities = 113/526 (21%), Positives = 182/526 (34%), Gaps = 90/526 (17%)
Query: 33 PAPGPAHRPPLVTAVVPPAGPLVLSAFPSTPLVAGQDGRGPSGAGASNVFVQMRTEVGPV 92
PAP P+ V PPA P P V + P V V + P
Sbjct: 9295 PAPEEVAPVPIPKKVEPPA--------PKVPEVP----KKPVPEEKKPVPVPKKEPAAPP 9342
Query: 93 KPPQAQTLILTQAPLVWQAPGTLCGGVMCPPPLLLAAAPGVPVTSAQVVGGTQACEGGWS 152
K P+ + + + P + PP + GV VT ++ TQ E
Sbjct: 9343 KVPEVPKKPVPEEKI----PVPVAKKKEAPPAKVPEVQKGV-VTEEKITIVTQREES--- 9394
Query: 153 HGLPLPPPPPAAQVAPIVSPGNARPWPQGAHGEGSLAPSQAKARPDDSCKPKSVYENFRL 212
PPP ++ P +P P+ E P + A P + V
Sbjct: 9395 ------PPPAVPEIPKKKVPEERKPVPRKE--EEVPPPPKVPALPKKPVPEEKVAVPV-- 9444
Query: 213 WQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLW------QAMREWQH 266
P+A++ P P E ++ R +A K + + + + A EW +
Sbjct: 9445 -----PVAKKAPP--PRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSY 9497
Query: 267 TSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQSLPPPAPPRLEPR---GPPAPEV 323
+ + + E+ E E EEE ++ + + M+ P+ + + PA
Sbjct: 9498 SEEEEGVSISVYREE--EREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVT 9555
Query: 324 VKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPR-PQRPA 382
+Q + K PK P PP + P K +P + P +PPP+ P+ P
Sbjct: 9556 ERQEKKIVLK--PKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPK 9613
Query: 383 ETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQREKGKVEQPQEEDGITSDPGLLS 442
+ +++PP+V++ MEE L + + Q EK V
Sbjct: 9614 KPVPEKKVPPKVIK-----MEEPLPAKVTERHMQITQEEKVLVA---------------- 9652
Query: 443 YIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLALSQELEQEEGLTLAQLVEKRLL 502
VTK EA R EE P+ L L + E+E A++ E R
Sbjct: 9653 -----------VTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPP---AKVTEFRKR 9698
Query: 503 SLKEKGCGRAAPRHGTARLDSSPSEFAAGQEAAREVPDPQQRVSVE 548
+KE+ AP+ R E +E R ++ VSV+
Sbjct: 9699 VVKEEKVSIEAPK----REPQPIKEVTIMEEKERAYTLEEEAVSVQ 9740
Score = 45.1 bits (105), Expect = 2e-04
Identities = 45/134 (33%), Positives = 56/134 (41%), Gaps = 44/134 (32%)
Query: 300 KGPQSLPP---------PAPPRLEPRGPP-----APEVV----KQPVYLPSKDG------ 335
K P+ LPP P PP +P PP AP+ V K PV P K
Sbjct: 10494 KVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKV 10553
Query: 336 PKAPTACLP--------PPRPQRPAETKAHLPPPRPQRPAET--NAHLPPPRPQRPAET- 384
P+ P A +P PP+P+ P PP P+ P E +P P++P T
Sbjct: 10554 PEVPKAAVPEKKVPEAIPPKPESP-------PPEVPEAPKEVVPEKKVPAAPPKKPEVTP 10606
Query: 385 -KVPEEIPPEVVQE 397
KVP E P EVV E
Sbjct: 10607 VKVP-EAPKEVVPE 10619
Score = 44.7 bits (104), Expect = 3e-04
Identities = 40/170 (23%), Positives = 73/170 (42%), Gaps = 27/170 (15%)
Query: 303 QSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQR--------PAET 354
+ +P P P ++E PEV K+PV P +P P P++ P
Sbjct: 10015 EKVPVPVPKKVEAPPAKVPEVPKKPV----------PEKKVPVPAPKKVEAPPAKVPEVP 10064
Query: 355 KAHLPPPRPQRPAETNAHLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDT 413
K +P + P PPP+ P++ VP +P E E V EE++ P +
Sbjct: 10065 KKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQE---EEVLFEEEIV---PEEE 10118
Query: 414 GEPEGQREKGKVEQ--PQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVI 461
PE + + E+ P+EE+ + + + +++ +E++V + E +
Sbjct: 10119 VLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFV 10168
Score = 42.7 bits (99), Expect = 0.001
Identities = 56/184 (30%), Positives = 84/184 (45%), Gaps = 46/184 (25%)
Query: 254 EEGLWQAMREW----QHTSNFDRMIFYEMAEKFLE-FEAEEEMQIQKSQWM-KGPQS--- 304
EEG + + E+ QH + + E + +E FEAEE +K + KGP+
Sbjct: 10391 EEGEFHEVEEFIKLEQHRVEEEHRV--EKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEK 10448
Query: 305 -LPPPAPP-RLEPRG-PPA--PEV-----VKQPVYLPSKDGPKAPTACLP---PPR---P 348
+PP PP ++ PR PPA PEV V++ V +P + P+ P +P PP+ P
Sbjct: 10449 IIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEE--PRVPPTKVPEVLPPKEVVP 10506
Query: 349 QR----PAETKAHLPPPR-PQRPAET----NAHLPPPRPQRPAETKVPE--------EIP 391
++ P K PPP+ P+ P E +PPP+ TKVPE +
Sbjct: 10507 EKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKV 10566
Query: 392 PEVV 395
PE +
Sbjct: 10567 PEAI 10570
Score = 42.4 bits (98), Expect = 0.002
Identities = 50/198 (25%), Positives = 84/198 (42%), Gaps = 40/198 (20%)
Query: 244 LARRKPTMTLEEGLWQAMRE--WQHTSNFDRMIF--YEMAEKFLEFEAEEEMQIQK---- 295
+ ++ TLEE RE ++ +D F YE E++ ++E EE + ++
Sbjct: 9723 MEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEH 9782
Query: 296 SQWMKGPQS-LP----PPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQR 350
+++ P+ +P P P +P+ PPA +V+K+ V P + P L PP P+
Sbjct: 9783 EEYITEPEKPIPVKPVPEEPVPTKPKAPPA-KVLKKAV--PEEKVPVPIPKKLKPPPPKV 9839
Query: 351 PAETK----------------------AHLPPPRPQRPAETNAHLPPPRPQRPAETKVPE 388
P E K A P +P+R +P PR + +VP
Sbjct: 9840 PEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKR-VVAEEKVPVPRKEVAPPVRVP- 9897
Query: 389 EIPPEVVQEYVDIMEELL 406
E+P E+ E V EE++
Sbjct: 9898 EVPKELEPEEVAFEEEVV 9915
Score = 41.6 bits (96), Expect = 0.003
Identities = 35/134 (26%), Positives = 56/134 (41%), Gaps = 35/134 (26%)
Query: 299 MKGPQSLPPPAP--------PRLEPRGPPAP-----EVVKQPVY----LPSKDGPKAPTA 341
+K P++ PP P P+L+PR PP P E VK+ ++ +P K P+ P
Sbjct: 10855 IKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQV 10914
Query: 342 -----CLPPPRPQRPAETKAHLPPPRPQ-------------RPAETNAHLPPPRPQRPAE 383
P P + + LP +P+ RP E + P + ++ +
Sbjct: 10915 PEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKK 10974
Query: 384 TKVPEEIPPEVVQE 397
VPE PP+ V+E
Sbjct: 10975 PAVPEPPPPKPVEE 10988
Score = 40.8 bits (94), Expect = 0.005
Identities = 49/204 (24%), Positives = 80/204 (39%), Gaps = 28/204 (13%)
Query: 309 APPRLEPRGPPAPEVVKQPVYLPSKDGPK-----------APTACLPPPRPQRPAETKAH 357
APP P P PE K PV +P K+ P P +P P P++ A
Sbjct: 9973 APPAKVPEVPKKPEE-KVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAK 10031
Query: 358 LP----PPRPQR----PAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSH 409
+P P P++ PA PP + + +PEE P V + V+ +
Sbjct: 10032 VPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKK 10091
Query: 410 ----PGDTGEPEGQREKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRF 465
P P+ + + E EE+ + + +L +++ +E+ V E I P
Sbjct: 10092 REPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPP-- 10149
Query: 466 LEELLSPDPQMDFLALSQELEQEE 489
EE P P+ +++ +E EE
Sbjct: 10150 -EEEEVP-PEEEYVPEEEEFVPEE 10171
Score = 40.8 bits (94), Expect = 0.005
Identities = 35/103 (33%), Positives = 42/103 (40%), Gaps = 15/103 (14%)
Query: 308 PAPPRLEPRGPP--APEVVKQPVYLPSKDGPKA--PTACLPPPRP-QRPAETKAHLPP-- 360
P PP +P PP PEV K V +P K P+A P PPP + P E PP
Sbjct: 10623 PVPPPKKPEVPPTKVPEVPK--VAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAE 10680
Query: 361 ----PRPQRPAETNA--HLPPPRPQRPAETKVPEEIPPEVVQE 397
P P P + P P + PA E+PP V E
Sbjct: 10681 VVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPE 10723
Score = 40.4 bits (93), Expect = 0.006
Identities = 43/172 (25%), Positives = 73/172 (42%), Gaps = 28/172 (16%)
Query: 285 FEAEEEMQIQK--SQWMKGPQSLPPP---APPRLEPRGPPAPEVVKQPVYLPSKDGPKAP 339
FE EE+ +++ ++ ++ P+ PP PP+ AP VV + LP P+ P
Sbjct: 10666 FEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVP 10725
Query: 340 TACLPPPR-----PQRPAETKAHLPP-PR----------PQRPAETNAHLP--PPRPQRP 381
+P + P++P A +P P+ P++P A +P P +P
Sbjct: 10726 KEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLE 10785
Query: 382 AETKVP-----EEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQREKGKVEQP 428
+ VP E PPEV +E +I E + + P + E+ +V P
Sbjct: 10786 EKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPP 10837
Score = 38.5 bits (88), Expect = 0.023
Identities = 46/188 (24%), Positives = 74/188 (39%), Gaps = 32/188 (17%)
Query: 306 PPPA----PPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPP------PRPQRPAETK 355
PPP P + P APE K PV + ++ P+ P +P P + P K
Sbjct: 10799 PPPEVYEEPEEIAPEEEIAPEEEK-PVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKK 10857
Query: 356 AHLPPPRPQRPAETNAH-----LPPPRPQRPAETKVPEE------IPPEVVQEYVDIMEE 404
PPP+ P + PPP P P + V E+ IP + V E + E+
Sbjct: 10858 PEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEK 10917
Query: 405 LLGSHPGDTGEPEGQREKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPR 464
+ P G+++ K+ P+ + + L S + K +E E + P+
Sbjct: 10918 V---ELTPLKVPGGEKKVRKL-LPERKPEPKEEVVLKSVLRKRPEEE------EPKVEPK 10967
Query: 465 FLEELLSP 472
LE++ P
Sbjct: 10968 KLEKVKKP 10975
Score = 38.1 bits (87), Expect = 0.030
Identities = 89/391 (22%), Positives = 143/391 (36%), Gaps = 71/391 (18%)
Query: 307 PPAPPRLEPRGPP--APE----VVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPP 360
P APP P P PE V K+P P+K P+ P + +P P +A PP
Sbjct: 10742 PEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKV-PEVPKKPVLEEKPAVPVPERAESPP 10800
Query: 361 P----RPQRPAETNAHLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELL-------GS 408
P P+ A P +P AE + PE PP V +E I+ E +
Sbjct: 10801 PEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEA 10860
Query: 409 HPGDTGEPEGQREKGKVE--------QPQEEDGITSDPGLLSYIDKLCSQEDFV------ 454
P EPE EK K++ P +ED L + K ++ V
Sbjct: 10861 PPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVEL 10920
Query: 455 TKVEAVIHPRFLEELL---SPDPQMDFL---ALSQELEQEEGLTLAQLVEKRLLSLKEKG 508
T ++ + + +LL P+P+ + + L + E+EE ++ K+L +K+
Sbjct: 10921 TPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEE----PKVEPKKLEKVKKPA 10976
Query: 509 CGRAAPRHGTARLDSSPSEFAAGQEAAREVPDPQQRVSVETSPPQTAAQ-DPQGQGRVRT 567
P + E + R++P+P + ++ + P A + P+ + V+T
Sbjct: 10977 VPEPPPPKPVEEV-----EVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKT 11031
Query: 568 GMARSEDPAVLLGCQDSPRLKAVRPTSPPQDHRPTCPGLGTKDALGLPGESPVKESHGLA 627
+ V P P T P +G K P E K G
Sbjct: 11032 -----------------IKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPK-GPI 11073
Query: 628 KGSSEETELPGMVYVVGSHHRLRPWRLSQSP 658
KG ++T P + +LRP + P
Sbjct: 11074 KGVPKKTPSP----IEAERRKLRPGSGGEKP 11100
Score = 37.7 bits (86), Expect = 0.040
Identities = 31/115 (26%), Positives = 46/115 (40%), Gaps = 13/115 (11%)
Query: 288 EEEMQIQKSQWMKGPQSLPPPAPPRLEPRGPPAPEVVKQPV-YLPSKDGPKAPTACLPPP 346
EE +I + + + P P EP PP P V ++P +P K P PPP
Sbjct: 10805 EEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPP-PAVPEEPKKIIPEKKVPVIKKPEAPPP 10863
Query: 347 RPQRPAET------KAHLPPPRPQRPAETNAH-----LPPPRPQRPAETKVPEEI 390
+ P + K PPP P P E P+ + P + +VPE++
Sbjct: 10864 KEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKV 10918
Score = 36.6 bits (83), Expect = 0.089
Identities = 61/297 (20%), Positives = 119/297 (40%), Gaps = 39/297 (13%)
Query: 288 EEEMQIQKSQWMKGPQSLPPPAPPRL---EPRGPPAPEVVK-QPVYLPSKDGPKAPTACL 343
E+++ + + ++ P + P P +L E + P P+ V+ P +P K P L
Sbjct: 10042 EKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVAL 10101
Query: 344 PPPRP---QRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVP---EEIPPEVVQE 397
P + + + P + E LP P E ++P EE+PPE +E
Sbjct: 10102 PQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPE--EE 10159
Query: 398 YVDIMEELLGSH------------PGDTGEPEGQREKGKVEQPQEEDGITSDPGLLSYID 445
YV EE + P E + + + KV P++E+ + P + +
Sbjct: 10160 YVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEE---APPAKVPEVP 10216
Query: 446 KLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLALSQELEQEEGLTLAQLVEKRLLSLK 505
K ++ + E + P + E +P +S+E EE ++ ++ E +
Sbjct: 10217 KKVEEKRIILPKEEEVLPVEVTEEPEEEP------ISEEEIPEEPPSIEEVEEVAPPRVP 10270
Query: 506 E--KGCGRAAPRHGTARLDSSPSEFAAGQEAAREVPDPQQRVSVETSPPQTAAQDPQ 560
E K AP ++++ P++ + + +VP P Q+ + +PP + P+
Sbjct: 10271 EVIKKAVPEAPTPVPKKVEAPPAK-VSKKIPEEKVPVPVQK---KEAPPAKVPEVPK 10323
Score = 36.6 bits (83), Expect = 0.089
Identities = 36/120 (30%), Positives = 54/120 (45%), Gaps = 31/120 (25%)
Query: 300 KGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPK---------APTACLPPPR--- 347
K P+++PP +P PP PEV ++P + ++ P AP PP+
Sbjct: 10649 KVPEAIPP------KPESPP-PEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPV 10701
Query: 348 PQRPAET----KAHLPP------PRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQE 397
P++ A K LPP P+ P + + P +P+ P KVP E+P EVV E
Sbjct: 10702 PEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAP-PAKVP-EVPKEVVPE 10759
Score = 35.0 bits (79), Expect = 0.26
Identities = 38/142 (26%), Positives = 61/142 (42%), Gaps = 23/142 (16%)
Query: 270 FDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQSLPPPAPPRLE--PRGPPAPEVVKQP 327
F+ + + E +E EEE I + + + + P P ++ PR P E K+P
Sbjct: 9910 FEEEVVTHVEEYLVE---EEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEE--KKP 9964
Query: 328 VYLPSK---------DGPKAPTACLPP--PRPQRPAETKAHLPPPRPQRPA-ETNAHLPP 375
V +P K + PK P +P P+ ++P K P P++P E +P
Sbjct: 9965 VPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKV---PEVPKKPVPEEKVPVPV 10021
Query: 376 PRPQRPAETKVPEEIPPEVVQE 397
P+ KVP E+P + V E
Sbjct: 10022 PKKVEAPPAKVP-EVPKKPVPE 10042
Score = 34.7 bits (78), Expect = 0.34
Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 3/80 (3%)
Query: 286 EAEEEMQIQKSQWMKGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPP 345
EAE + IQK++ + + PP EPR +PE VK P + S + P P A P
Sbjct: 32643 EAEFTLTIQKARVTEKAVTSPPRVKSP-EPR-VKSPEAVKSPKRVKSPE-PSHPKAVSPT 32699
Query: 346 PRPQRPAETKAHLPPPRPQR 365
P E HLP P +
Sbjct: 32700 ETKPTPTEKVQHLPVSAPPK 32719
Score = 33.5 bits (75), Expect = 0.75
Identities = 99/450 (22%), Positives = 156/450 (34%), Gaps = 89/450 (19%)
Query: 28 LPFATPAPGPAHRPPLV------TAVVPPAGPLVLSAFPSTPLVAGQDGRGPSGAGASNV 81
+P A P P P PP V A+ P +V P+ P + P +
Sbjct: 10650 VPEAIP-PKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPA 10708
Query: 82 FVQMRTEVGPVKPPQAQTLILTQ--APLVW----QAPGT----LCGGVMCPPPLLLAAAP 131
V + E+ PVK P+ ++ + PLV +AP + V+ + + P
Sbjct: 10709 VVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKP 10768
Query: 132 GVPVTSAQVVGGTQACEGGWSHGLPLPP----PPPAA-----QVAPI--VSPGNARPWPQ 180
VP V E +P+P PPP ++AP ++P +P P
Sbjct: 10769 EVPPAKVPEVPKKPVLEE--KPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPV 10826
Query: 181 GAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPV 240
E + P A P++ PK + ++ KP A P+ P+ E + P
Sbjct: 10827 AEEEEPEVPPP---AVPEE---PKKIIPEKKVPVIKKPEAPP--PKEPEPEKV--IEKPK 10876
Query: 241 LRSLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMK 300
L+ P +E ++ EK + +A + ++ + +
Sbjct: 10877 LKPRPPPPPPAPPKE---------------------DVKEKIFQLKAIPKKKVPEKPQVP 10915
Query: 301 GPQSLPPPAPP-------RLEPRGPPAP--EVVKQPVYL--PSKDGPKAPTACL------ 343
L P P +L P P P EVV + V P ++ PK L
Sbjct: 10916 EKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKP 10975
Query: 344 -----PPPRP----QRPAETKAHLPPPRPQRPAETNAH--LPPPRPQRPAETKVPEEIPP 392
PPP+P + P TK P P + E LP P P+ E +V PP
Sbjct: 10976 AVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPP 11035
Query: 393 EVVQEYVDIMEELLGSHPGDTGEPEGQREK 422
V E I + G E + +E+
Sbjct: 11036 PVEPEPTPIAAPVTVPVVGKKAEAKAPKEE 11065
Score = 33.1 bits (74), Expect = 0.98
Identities = 31/120 (25%), Positives = 46/120 (38%), Gaps = 13/120 (10%)
Query: 271 DRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQSLPPPAPPRLEPRGPP-APEVVKQPVY 329
++ I E+ L E EE + + + P+ PP+ +E PP PEV+K+ V
Sbjct: 10221 EKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEE--PPSIEEVEEVAPPRVPEVIKKAV- 10277
Query: 330 LPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVPEE 389
P+AP P P+ K P + P PP KVPE+
Sbjct: 10278 ------PEAP---TPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEK 10328
Score = 32.3 bits (72), Expect = 1.7
Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 37/163 (22%)
Query: 275 FYEMAEKFLEFEAE--------EEMQIQKSQWMKGPQSLPPPAPPRLEPRGPPAPEVVKQ 326
+YE E + E E E E +Q+QK + + + P P E + PP P+V+K+
Sbjct: 9126 YYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVP--EKKAPPPPKVIKK 9183
Query: 327 PVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQ--RPAETNAHLPPPRPQR-PAE 383
PV ++ +T + + Q + E + + P +P R P +
Sbjct: 9184 PVI-------------------EKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQ 9224
Query: 384 TKVPEEIPPEVVQEYVDIMEE--LLGSHPGD---TGEPEGQRE 421
+V E P V + + I EE SH + PE Q+E
Sbjct: 9225 EEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKE 9267
Score = 31.6 bits (70), Expect = 2.8
Identities = 31/129 (24%), Positives = 47/129 (36%), Gaps = 22/129 (17%)
Query: 302 PQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPP 361
P+ +PP P + P+ LP+ + K P + + + K + P
Sbjct: 8954 PEEIPPVVAPPI-------------PLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKP 9000
Query: 362 RPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQRE 421
+ P E PPP P K PE I E V IM T + E Q+E
Sbjct: 9001 KEMTPREEIVKKPPP-PTTLIPAKAPEIIDVSSKAEEVKIMT--------ITRKKEVQKE 9051
Query: 422 KGKVEQPQE 430
K V + ++
Sbjct: 9052 KEAVYEKKQ 9060
Score = 31.6 bits (70), Expect = 2.8
Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 3/69 (4%)
Query: 336 PKAPTACLPPPRPQRPAETKAHLPPPR-PQRPAETNAHLPP--PRPQRPAETKVPEEIPP 392
P+ P +P + P K PP + P+ P + +P P+ ++P KVPE
Sbjct: 9951 PEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKK 10010
Query: 393 EVVQEYVDI 401
V +E V +
Sbjct: 10011 PVPEEKVPV 10019
>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
member 1 interacting protein [Homo sapiens]
Length = 666
Score = 50.1 bits (118), Expect = 8e-06
Identities = 35/112 (31%), Positives = 43/112 (38%), Gaps = 21/112 (18%)
Query: 306 PPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQR 365
PPP PP +P PP P +P P +PPP P + LPPP P
Sbjct: 557 PPPPPPLDDPELPPPPPDFMEP-----------PPDFVPPPPPSYAGIAGSELPPPPPPP 605
Query: 366 PAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPE 417
PA A +P PA K P +PP+ + HPG G E
Sbjct: 606 PAPAPAPVPDSARPPPAVAKRP-PVPPKRQEN---------PGHPGGAGGGE 647
Score = 32.0 bits (71), Expect = 2.2
Identities = 28/106 (26%), Positives = 37/106 (34%), Gaps = 23/106 (21%)
Query: 332 SKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQR-----------------------PAE 368
SKD A P P+ P K+ LPPP P R PA
Sbjct: 490 SKDKKPALGNHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAP 549
Query: 369 TNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTG 414
+ LPPP P P + PP+ ++ D + S+ G G
Sbjct: 550 PDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAG 595
Score = 30.8 bits (68), Expect = 4.9
Identities = 44/157 (28%), Positives = 55/157 (35%), Gaps = 40/157 (25%)
Query: 33 PAPGPAHRPPLVTAV------VPPAGPLVLSA----FPSTPLVAGQDGRGPSGAGASNVF 82
PA G H P + A +PP P+ S+ P+TPL A G G A +
Sbjct: 495 PALGNHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFL 554
Query: 83 VQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVMCPPPLLLAAAPGVPVTSAQVVG 142
P PP L P + P PP + P P + A + G
Sbjct: 555 PP------PPPPPPLDDPELPPPPPDFMEP---------PPDFV----PPPPPSYAGIAG 595
Query: 143 GTQACEGGWSHGLPLPPPPPAAQVAPIVSPGNARPWP 179
LP PPPPP AP P +ARP P
Sbjct: 596 SE----------LP-PPPPPPPAPAPAPVPDSARPPP 621
Score = 30.0 bits (66), Expect = 8.3
Identities = 21/71 (29%), Positives = 26/71 (36%), Gaps = 10/71 (14%)
Query: 288 EEEMQIQKSQWMKGPQSLPPPAPP--------RLEPRGPPAPEVVKQPVYLPSKDGPKAP 339
+ E+ +M+ P PP PP L P PP P PV P P
Sbjct: 565 DPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPV--PDSARPPPA 622
Query: 340 TACLPPPRPQR 350
A PP P+R
Sbjct: 623 VAKRPPVPPKR 633
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.133 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,691,537
Number of Sequences: 37866
Number of extensions: 3126379
Number of successful extensions: 31787
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 322
Number of HSP's successfully gapped in prelim test: 1349
Number of HSP's that attempted gapping in prelim test: 16736
Number of HSP's gapped (non-prelim): 11508
length of query: 756
length of database: 18,247,518
effective HSP length: 110
effective length of query: 646
effective length of database: 14,082,258
effective search space: 9097138668
effective search space used: 9097138668
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.