Search of human proteins with 148727331

Search of human proteins with 148727331

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148727331 ubiquitin specific peptidase 5 isoform 1 [Homo
sapiens]
         (858 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148727331 ubiquitin specific peptidase 5 isoform 1 [Homo sapi...  1749   0.0  
gi|148727247 ubiquitin specific peptidase 5 isoform 2 [Homo sapi...  1685   0.0  
gi|215598688 ubiquitin thiolesterase 13 [Homo sapiens]               1068   0.0  
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]             77   7e-14
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]             77   7e-14
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]             77   7e-14
gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]                   77   9e-14
gi|71774197 ubiquitin specific protease 47 [Homo sapiens]              61   5e-09
gi|41152235 ubiquitin specific protease 51 [Homo sapiens]              60   9e-09
gi|21361517 UBX domain protein 1 [Homo sapiens]                        60   1e-08
gi|45267835 ubiquitin specific protease 50 [Homo sapiens]              56   1e-07
gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens]             55   2e-07
gi|55770884 ubiquitin associated domain containing 1 [Homo sapiens]    55   3e-07
gi|62243586 ubiquitin-specific protease 21 [Homo sapiens]              54   8e-07
gi|74027267 ubiquitin-specific protease 21 [Homo sapiens]              54   8e-07
gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens]                 53   1e-06
gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens]                 53   1e-06
gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens]                  52   2e-06
gi|21361749 ubiquitin thioesterase 49 [Homo sapiens]                   52   3e-06
gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens]     52   3e-06
gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens]     52   3e-06
gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]    49   3e-05
gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapi...    49   3e-05
gi|57529246 ubiquitin thioesterase 19 [Homo sapiens]                   47   8e-05
gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]            47   1e-04
gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sap...    46   1e-04
gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapi...    46   1e-04
gi|56550051 ubiquitin specific protease 39 [Homo sapiens]              46   2e-04
gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens]             45   4e-04
gi|188497648 ubiquitin specific peptidase 37 [Homo sapiens]            45   4e-04

>gi|148727331 ubiquitin specific peptidase 5 isoform 1 [Homo
           sapiens]
          Length = 858

 Score = 1749 bits (4531), Expect = 0.0
 Identities = 858/858 (100%), Positives = 858/858 (100%)

Query: 1   MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVER 60
           MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVER
Sbjct: 1   MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVER 60

Query: 61  HFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDV 120
           HFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDV
Sbjct: 61  HFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDV 120

Query: 121 KIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHA 180
           KIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHA
Sbjct: 121 KIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHA 180

Query: 181 FSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRET 240
           FSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRET
Sbjct: 181 FSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRET 240

Query: 241 GYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDM 300
           GYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDM
Sbjct: 241 GYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDM 300

Query: 301 NQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEK 360
           NQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEK
Sbjct: 301 NQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEK 360

Query: 361 IFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKAL 420
           IFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKAL
Sbjct: 361 IFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKAL 420

Query: 421 IGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYT 480
           IGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYT
Sbjct: 421 IGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYT 480

Query: 481 QRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPE 540
           QRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPE
Sbjct: 481 QRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPE 540

Query: 541 QVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDIS 600
           QVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDIS
Sbjct: 541 QVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDIS 600

Query: 601 QLRGTGLQPGEEELPDIAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVI 660
           QLRGTGLQPGEEELPDIAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVI
Sbjct: 601 QLRGTGLQPGEEELPDIAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVI 660

Query: 661 IQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAA 720
           IQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAA
Sbjct: 661 IQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAA 720

Query: 721 DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSA 780
           DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSA
Sbjct: 721 DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSA 780

Query: 781 ADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCAS 840
           ADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCAS
Sbjct: 781 ADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCAS 840

Query: 841 EKPPKDLGYIYFYQRVAS 858
           EKPPKDLGYIYFYQRVAS
Sbjct: 841 EKPPKDLGYIYFYQRVAS 858


>gi|148727247 ubiquitin specific peptidase 5 isoform 2 [Homo
           sapiens]
          Length = 835

 Score = 1685 bits (4363), Expect = 0.0
 Identities = 834/858 (97%), Positives = 835/858 (97%), Gaps = 23/858 (2%)

Query: 1   MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVER 60
           MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVER
Sbjct: 1   MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVER 60

Query: 61  HFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDV 120
           HFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDV
Sbjct: 61  HFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDV 120

Query: 121 KIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHA 180
           KIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHA
Sbjct: 121 KIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHA 180

Query: 181 FSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRET 240
           FSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRET
Sbjct: 181 FSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRET 240

Query: 241 GYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDM 300
           GYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDM
Sbjct: 241 GYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDM 300

Query: 301 NQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEK 360
           NQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEK
Sbjct: 301 NQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEK 360

Query: 361 IFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKAL 420
           IFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKAL
Sbjct: 361 IFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKAL 420

Query: 421 IGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYT 480
           IGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYT
Sbjct: 421 IGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYT 480

Query: 481 QRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPE 540
           QRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPE
Sbjct: 481 QRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPE 540

Query: 541 QVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDIS 600
           QVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDIS
Sbjct: 541 QVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDIS 600

Query: 601 QLRGTGLQPGEEELPDIAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVI 660
           QLRGTGLQPGEEELPDIAPPLVTPDEPK                       +PMLDESVI
Sbjct: 601 QLRGTGLQPGEEELPDIAPPLVTPDEPK-----------------------APMLDESVI 637

Query: 661 IQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAA 720
           IQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAA
Sbjct: 638 IQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAA 697

Query: 721 DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSA 780
           DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSA
Sbjct: 698 DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSA 757

Query: 781 ADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCAS 840
           ADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCAS
Sbjct: 758 ADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCAS 817

Query: 841 EKPPKDLGYIYFYQRVAS 858
           EKPPKDLGYIYFYQRVAS
Sbjct: 818 EKPPKDLGYIYFYQRVAS 835


>gi|215598688 ubiquitin thiolesterase 13 [Homo sapiens]
          Length = 863

 Score = 1068 bits (2762), Expect = 0.0
 Identities = 518/862 (60%), Positives = 667/862 (77%), Gaps = 34/862 (3%)

Query: 7   EALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVERHFNKTG 66
           E L+  +PTIRVP++GDRV+K+ECAFS+D+P SEGGLY+CMNTFL FG+++VERHF KTG
Sbjct: 26  ELLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEGGLYVCMNTFLAFGREHVERHFRKTG 85

Query: 67  QRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDVKIVILP 126
           Q VY+HL+R  R K    + G    P+++ +++ + ++   DL+ + +E +++ K+VI P
Sbjct: 86  QSVYMHLKRHVREKVRGASGGA--LPKRRNSKIFLDLDTDDDLNSDDYEYEDEAKLVIFP 143

Query: 127 DYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHAFSLKQL 186
           D+ EIA   +  LP +V    T A +A+LS+ S  RKQ+   W+ E+  VSK+A +L QL
Sbjct: 144 DHYEIALPNIEELPALV----TIACDAVLSSKSPYRKQDPDTWENEL-PVSKYANNLTQL 198

Query: 187 DNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYPLAV 246
           DN  RIPP GWKC++CD+RENLWLNLTDGS+LCG+ +FD SGGN HA+EHYR+ GYPLAV
Sbjct: 199 DNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSGGNGHALEHYRDMGYPLAV 258

Query: 247 KLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDMNQRIGE 306
           KLGTITPDGADVYS+ E++ VLDP LA+HL+HFGIDML M  T+  + + +I +  R+ E
Sbjct: 259 KLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHGTENGLQDNDIKL--RVSE 316

Query: 307 WELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAP 366
           WE+IQESG  LKP++GPGYTG++NLGNSCYL+SV+Q +FSIP+FQR YV  L +IF  +P
Sbjct: 317 WEVIQESGTKLKPMYGPGYTGLKNLGNSCYLSSVMQAIFSIPEFQRAYVGNLPRIFDYSP 376

Query: 367 TDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERV--PEQKEVQDGIAPRMFKALIGKG 424
            DPTQDF+TQ+ KLGHGLLSG+YSKP  +S   E+V   E K  Q+GI+PRMFKA + K 
Sbjct: 377 LDPTQDFNTQMTKLGHGLLSGQYSKPPVKSELIEQVMKEEHKPQQNGISPRMFKAFVSKS 436

Query: 425 HPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVD 484
           HPEFS+NRQQDAQEFFLHL+N+VERN   SENP++VFRFLVEE+I+C  T KV+YT+RVD
Sbjct: 437 HPEFSSNRQQDAQEFFLHLVNLVERNRIGSENPSDVFRFLVEERIQCCQTRKVRYTERVD 496

Query: 485 YIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDD 544
           Y+MQLPV M+AA NK+EL+ YE  +R+AE  +  LPELVRA++PFS+CL+A+  PE VDD
Sbjct: 497 YLMQLPVAMEAATNKDELIAYELTRREAEANRRPLPELVRAKIPFSACLQAFSEPENVDD 556

Query: 545 FWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLRG 604
           FWS+ALQAKS  VKT+RFASFP+YLV+QIKKFTFGLDWVPKK DVSI+MP+ LDI+ LR 
Sbjct: 557 FWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKFDVSIDMPDLLDINHLRA 616

Query: 605 TGLQPGEEELPDIAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVIIQLV 664
            GLQPGEEELPDI+PP+V PD+ K  L     +  D              +DES ++QL 
Sbjct: 617 RGLQPGEEELPDISPPIVIPDDSKDRLMNQLIDPSD--------------IDESSVMQLA 662

Query: 665 EMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAA---- 720
           EMGFP++ACRKAVY+TGN GAE A NW++ HM++PDFA PL +PG  G  S  A+     
Sbjct: 663 EMGFPLEACRKAVYFTGNMGAEVAFNWIIVHMEEPDFAEPLTMPGYGGAASAGASVFGAS 722

Query: 721 ---DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHID-DLDAEAAMDISE 776
              + PPE+ V  I SMGF R+QA++ALRATNN+LERA+DWIFSH + + D++  +++ E
Sbjct: 723 GLDNQPPEEIVAIITSMGFQRNQAIQALRATNNNLERALDWIFSHPEFEEDSDFVIEM-E 781

Query: 777 GRSAADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQK 836
             + A+ ISE+ P GP+V+DG G Y+LFAFISHMGTSTM GHY+CHIKKEGRWVIYND K
Sbjct: 782 NNANANIISEAKPEGPRVKDGSGTYELFAFISHMGTSTMSGHYICHIKKEGRWVIYNDHK 841

Query: 837 VCASEKPPKDLGYIYFYQRVAS 858
           VCASE+PPKDLGY+YFY+R+ S
Sbjct: 842 VCASERPPKDLGYMYFYRRIPS 863


>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 77.0 bits (188), Expect = 7e-14
 Identities = 77/299 (25%), Positives = 138/299 (46%), Gaps = 38/299 (12%)

Query: 317  LKPLFG---PGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDF 373
            L P+FG   P  TG+RNLGN+CY+NS++Q L + P     Y ++          +  QD 
Sbjct: 765  LNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHL-ADYFNR----------NCYQDD 813

Query: 374  STQVAKLGH-GLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNR 432
              +   LGH G ++ E+   +     G+           I+P+ FK  IGK + +F+   
Sbjct: 814  INRSNLLGHKGEVAEEFGIIMKALWTGQ--------YRYISPKDFKITIGKINDQFAGYS 865

Query: 433  QQDAQEFFLHLINMVERNCRSSENPNEVFRFLVE-----EKIKCLATEKVKYTQRVDYIM 487
            QQD+QE  L L++ +  +   ++N     R+  E     +  K       K+ Q  + I+
Sbjct: 866  QQDSQELLLFLMDGLHEDLNKADNRK---RYKEENNDHLDDFKAAEHAWQKHKQLNESII 922

Query: 488  QLPVPMDAALNKEELLEYEEKKRQAEE-EKMALPELVRAQVPFSSCLEAYGAPEQVDD-- 544
             + +      +  + L   +K R  E    ++LP    ++     CL  +   E++ D  
Sbjct: 923  -VALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNN 981

Query: 545  -FWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMP-EELDISQ 601
             F+ +  +A+  ++K       P  L++ +K+F++   W  +KL  S++ P E LD+SQ
Sbjct: 982  RFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW-KQKLQTSVDFPLENLDLSQ 1039


>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 77.0 bits (188), Expect = 7e-14
 Identities = 77/299 (25%), Positives = 138/299 (46%), Gaps = 38/299 (12%)

Query: 317  LKPLFG---PGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDF 373
            L P+FG   P  TG+RNLGN+CY+NS++Q L + P     Y ++          +  QD 
Sbjct: 765  LNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHL-ADYFNR----------NCYQDD 813

Query: 374  STQVAKLGH-GLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNR 432
              +   LGH G ++ E+   +     G+           I+P+ FK  IGK + +F+   
Sbjct: 814  INRSNLLGHKGEVAEEFGIIMKALWTGQ--------YRYISPKDFKITIGKINDQFAGYS 865

Query: 433  QQDAQEFFLHLINMVERNCRSSENPNEVFRFLVE-----EKIKCLATEKVKYTQRVDYIM 487
            QQD+QE  L L++ +  +   ++N     R+  E     +  K       K+ Q  + I+
Sbjct: 866  QQDSQELLLFLMDGLHEDLNKADNRK---RYKEENNDHLDDFKAAEHAWQKHKQLNESII 922

Query: 488  QLPVPMDAALNKEELLEYEEKKRQAEE-EKMALPELVRAQVPFSSCLEAYGAPEQVDD-- 544
             + +      +  + L   +K R  E    ++LP    ++     CL  +   E++ D  
Sbjct: 923  -VALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNN 981

Query: 545  -FWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMP-EELDISQ 601
             F+ +  +A+  ++K       P  L++ +K+F++   W  +KL  S++ P E LD+SQ
Sbjct: 982  RFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW-KQKLQTSVDFPLENLDLSQ 1039


>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 77.0 bits (188), Expect = 7e-14
 Identities = 77/299 (25%), Positives = 138/299 (46%), Gaps = 38/299 (12%)

Query: 317  LKPLFG---PGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDF 373
            L P+FG   P  TG+RNLGN+CY+NS++Q L + P     Y ++          +  QD 
Sbjct: 765  LNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHL-ADYFNR----------NCYQDD 813

Query: 374  STQVAKLGH-GLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNR 432
              +   LGH G ++ E+   +     G+           I+P+ FK  IGK + +F+   
Sbjct: 814  INRSNLLGHKGEVAEEFGIIMKALWTGQ--------YRYISPKDFKITIGKINDQFAGYS 865

Query: 433  QQDAQEFFLHLINMVERNCRSSENPNEVFRFLVE-----EKIKCLATEKVKYTQRVDYIM 487
            QQD+QE  L L++ +  +   ++N     R+  E     +  K       K+ Q  + I+
Sbjct: 866  QQDSQELLLFLMDGLHEDLNKADNRK---RYKEENNDHLDDFKAAEHAWQKHKQLNESII 922

Query: 488  QLPVPMDAALNKEELLEYEEKKRQAEE-EKMALPELVRAQVPFSSCLEAYGAPEQVDD-- 544
             + +      +  + L   +K R  E    ++LP    ++     CL  +   E++ D  
Sbjct: 923  -VALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNN 981

Query: 545  -FWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMP-EELDISQ 601
             F+ +  +A+  ++K       P  L++ +K+F++   W  +KL  S++ P E LD+SQ
Sbjct: 982  RFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW-KQKLQTSVDFPLENLDLSQ 1039


>gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
          Length = 520

 Score = 76.6 bits (187), Expect = 9e-14
 Identities = 116/525 (22%), Positives = 197/525 (37%), Gaps = 104/525 (19%)

Query: 194 PCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYPLAVKLGTITP 253
           P  W CS C   ++ W+ LT  S+ CGR        N HA +HY +   PL     +   
Sbjct: 24  PSSWCCSVCRSNKSPWVCLTCSSVHCGRYV------NGHAKKHYEDAQVPLTNHKKSEKQ 77

Query: 254 DGAD-----------VYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDM-- 300
           D               Y Y  DD V++ +        G+    +QK  + +  LE     
Sbjct: 78  DKVQHTVCMDCSSYSTYCYRCDDFVVNDT------KLGL----VQKVREHLQNLENSAFT 127

Query: 301 NQRIGEWELIQESGVPLKPLFGPGYT------GIRNLGNSCYLNSVVQVLFSIPDFQRKY 354
             R  + +L++ S +  K L   G T      G+RNLGN+C++N+++Q L +I  F   +
Sbjct: 128 ADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYF 187

Query: 355 VDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAP 414
            +      +N  T   + + T+     +  L  E+ K +     G         Q   +P
Sbjct: 188 KELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGS--------QTAFSP 239

Query: 415 RMFKALIGKGHPEFSTNRQQDAQEFFLHLI-----------NMVERNCRSSENP------ 457
                ++ K  P F   +QQDA EF  +L+           N V R+    EN       
Sbjct: 240 ESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASN 299

Query: 458 -----------NEVFRFLVEEKIKCL--ATEKVKYTQRVDYIMQLPVPMDAALNKEELLE 504
                        +F  +++ ++ CL   TE  K+   +D  + +P              
Sbjct: 300 KCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQF----------- 348

Query: 505 YEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDD---FWSTALQAKSVAVKTTR 561
               KR   +E   +  L         CL ++   E++D+   +     + K  + K   
Sbjct: 349 --RSKRSKNQENGPVCSL-------RDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFW 399

Query: 562 FASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMP-EELDISQLRGTGLQPGEEE-LPDIAP 619
               P  L + +K+F +   ++  K+D  +E P   LD+          G E  L D+A 
Sbjct: 400 IQKLPKVLCLHLKRFHW-TAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAA 458

Query: 620 PLVTPDEPKGSLGF--YGNEDEDSFCSPHFSSPTSPMLDESVIIQ 662
            +V      GS  +  Y   +   F   HF+  T  + DE  +++
Sbjct: 459 VVVHHGSGVGSGHYTAYATHEGRWF---HFNDSTVTLTDEETVVK 500



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 2/55 (3%)

Query: 801 YQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCASEKPP--KDLGYIYFY 853
           Y L A + H G+    GHY  +   EGRW  +ND  V  +++    K   YI FY
Sbjct: 454 YDLAAVVVHHGSGVGSGHYTAYATHEGRWFHFNDSTVTLTDEETVVKAKAYILFY 508


>gi|71774197 ubiquitin specific protease 47 [Homo sapiens]
          Length = 1287

 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 66/284 (23%), Positives = 118/284 (41%), Gaps = 58/284 (20%)

Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHG 383
           GY G+ N   +CYLNS++Q LF  P+F R  + K E  F+ +  DP      Q+ +L   
Sbjct: 98  GYVGLVNQAMTCYLNSLLQTLFMTPEF-RNALYKWE--FEESEEDPVTSIPYQLQRLFVL 154

Query: 384 LLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHL 443
           L                +  +++ ++     R F      G       +Q D QE    +
Sbjct: 155 L----------------QTSKKRAIETTDVTRSF------GWDSSEAWQQHDVQELCRVM 192

Query: 444 INMVERNCRSSENP---NEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKE 500
            + +E+  + +E     NE+++  +++ ++CL      +  R+D  + +P+ +    + +
Sbjct: 193 FDALEQKWKQTEQADLINELYQGKLKDYVRCLECGYEGW--RIDTYLDIPLVIRPYGSSQ 250

Query: 501 ELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVD---DFWSTALQAKSVAV 557
                EE                         L A+  PE +D    ++    + K  A 
Sbjct: 251 AFASVEE------------------------ALHAFIQPEILDGPNQYFCERCKKKCDAR 286

Query: 558 KTTRFASFPDYLVIQIKKFTFGLDWVPK-KLDVSIEMPEELDIS 600
           K  RF  FP  L +Q+K+F F    + + KL+  +  PEELD+S
Sbjct: 287 KGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMS 330


>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
          Length = 711

 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 69/331 (20%), Positives = 128/331 (38%), Gaps = 51/331 (15%)

Query: 318 KPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQV 377
           K ++  G  G+ NLGN+C++N +VQ L  IP  +  ++    K      T P+     ++
Sbjct: 355 KSVYTVGLRGLINLGNTCFMNCIVQALTHIPLLKDFFLSDKHKCIM---TSPSLCLVCEM 411

Query: 378 AKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQ 437
           + L H + SG  +  +P                         LI       +  RQQDA 
Sbjct: 412 SSLFHAMYSGSRTPHIPYK--------------------LLHLIWIHAEHLAGYRQQDAH 451

Query: 438 EFFLHLINMVERNCR------SSENPN-------EVFRFLVEEKIKCLATEKVKYTQRVD 484
           EF + +++++ R+ +       + NPN       ++F   ++  + C A   V  T    
Sbjct: 452 EFLIAILDVLHRHSKDDSGGQEANNPNCCNCIIDQIFTGGLQSDVTCQACHSVSTTIDPC 511

Query: 485 YIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDD 544
           + + L +P   A    +  E  +     ++    +P L       + CL+ +  PE +  
Sbjct: 512 WDISLDLPGSCATFDSQNPERADSTVSRDDHIPGIPSL-------TDCLQWFTRPEHLGS 564

Query: 545 ---FWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQ 601
                  + Q+   + K       P      +K+F   +    +K++  I  P ELD++ 
Sbjct: 565 SAKIKCNSCQSYQESTKQLTMKKLPIVACFHLKRFEH-VGKQRRKINTFISFPLELDMTP 623

Query: 602 LRGTGLQPGEEELPDIAPPL-VTPDEPKGSL 631
              +     E  + +  PP    P+E K SL
Sbjct: 624 FLAS---TKESRMKEGQPPTDCVPNENKYSL 651



 Score = 30.8 bits (68), Expect = 5.6
 Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 8/61 (13%)

Query: 800 KYQLFAFISHMGTSTMCGHYVCHIKKE-GRWVIYNDQKVCASEKPPKDL----GYIYFYQ 854
           KY LFA I+H GT    GHY   I+++  +W   +D  +  ++   +DL    GY+ FY 
Sbjct: 648 KYSLFAVINHHGT-LESGHYTSFIRQQKDQWFSCDDAII--TKATIEDLLYSEGYLLFYH 704

Query: 855 R 855
           +
Sbjct: 705 K 705


>gi|21361517 UBX domain protein 1 [Homo sapiens]
          Length = 312

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 27/55 (49%), Positives = 34/55 (61%)

Query: 654 MLDESVIIQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILP 708
           M + + +  L+EMGFP     KA+  TGN G EAAM+W+M H DDPD   PL  P
Sbjct: 1   MAELTALESLIEMGFPRGRAEKALALTGNQGIEAAMDWLMEHEDDPDVDEPLETP 55



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 19/49 (38%), Positives = 29/49 (59%), Gaps = 1/49 (2%)

Query: 730 TIVSMGFSRDQALKALRATNNS-LERAVDWIFSHIDDLDAEAAMDISEG 777
           +++ MGF R +A KAL  T N  +E A+DW+  H DD D +  ++   G
Sbjct: 9   SLIEMGFPRGRAEKALALTGNQGIEAAMDWLMEHEDDPDVDEPLETPLG 57


>gi|45267835 ubiquitin specific protease 50 [Homo sapiens]
          Length = 339

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 51/199 (25%), Positives = 80/199 (40%), Gaps = 53/199 (26%)

Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIPDFQR-----KYVDKLEKIFQNAPTDPTQDFSTQVA 378
           G TG+ NLGN+C +N++ Q L SI          KY+  L+K     P+D   + +T  A
Sbjct: 42  GVTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFL--LPSD-CSEVATAFA 98

Query: 379 KLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQE 438
            L   +  G+                     D ++P +F + +G  +P F+   QQDAQE
Sbjct: 99  YLMTDMWLGD--------------------SDCVSPEIFWSALGNLYPAFTKKMQQDAQE 138

Query: 439 FFLHLIN--------------------MVERNCR-----SSENPNEVFRFLVEEKIKCLA 473
           F + ++N                      +R CR      +    ++F   +   I CL 
Sbjct: 139 FLICVLNELHEALKKYHYSRRRSYEKGSTQRCCRKWITTETSIITQLFEEQLNYSIVCLK 198

Query: 474 TEKVKYTQRVDYIMQLPVP 492
            EK  Y   V  +  LP+P
Sbjct: 199 CEKCTYKNEVFTVFSLPIP 217


>gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens]
          Length = 952

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 36/125 (28%), Positives = 60/125 (48%), Gaps = 22/125 (17%)

Query: 323 PGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYV-DKL-EKIFQNAPTDPTQDFSTQVAKL 380
           PG  G+ NLGN+C++NS +Q L + P     ++ DK  E++  + P     + +   A+L
Sbjct: 257 PGLCGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAEL 316

Query: 381 GHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFF 440
              + SG++S                     + PR FK  +G+  P+FS  +QQD QE  
Sbjct: 317 IKQMWSGKFSY--------------------VTPRAFKTQVGRFAPQFSGYQQQDCQELL 356

Query: 441 LHLIN 445
             L++
Sbjct: 357 AFLLD 361



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 31/127 (24%), Positives = 56/127 (44%), Gaps = 12/127 (9%)

Query: 482 RVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPF---SSCLEAYGA 538
           R+D    L +  D  L K     Y ++    + EK    E    + PF     C+E +  
Sbjct: 713 RLDERSFLALDWDPDLKKR----YFDENAAEDFEKHESVEYKPPKKPFVKLKDCIELFTT 768

Query: 539 PEQV---DDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMP- 594
            E++   D ++    +    A K     S P  LV+ +K+F++   ++  KLD  ++ P 
Sbjct: 769 KEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSYS-RYMRDKLDTLVDFPI 827

Query: 595 EELDISQ 601
            +LD+S+
Sbjct: 828 NDLDMSE 834


>gi|55770884 ubiquitin associated domain containing 1 [Homo sapiens]
          Length = 405

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 40/137 (29%), Positives = 60/137 (43%), Gaps = 35/137 (25%)

Query: 655 LDESVIIQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGP- 713
           +DE+ + QL EMGFP +   KA+     S  +A M W++ H +DP    PL  PG + P 
Sbjct: 192 VDEAALRQLTEMGFPENRATKALQLNHMSVPQA-MEWLIEHAEDPTIDTPL--PGQAPPE 248

Query: 714 --GSTSAAA---------DPPPED--------------------CVTTIVSMGFSRDQAL 742
             G+T+AA+         D    D                     V +++ MGF   + +
Sbjct: 249 AEGATAAASEAAAGASATDEEARDELTEIFKKIRRKREFRADARAVISLMEMGFDEKEVI 308

Query: 743 KALRATNNSLERAVDWI 759
            ALR  NN    A +W+
Sbjct: 309 DALRVNNNQQNAACEWL 325



 Score = 34.7 bits (78), Expect = 0.39
 Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 5/64 (7%)

Query: 725 EDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEA-----AMDISEGRS 779
           E  +  +  MGF  ++A KAL+  + S+ +A++W+  H +D   +      A   +EG +
Sbjct: 194 EAALRQLTEMGFPENRATKALQLNHMSVPQAMEWLIEHAEDPTIDTPLPGQAPPEAEGAT 253

Query: 780 AADS 783
           AA S
Sbjct: 254 AAAS 257


>gi|62243586 ubiquitin-specific protease 21 [Homo sapiens]
          Length = 565

 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 44/150 (29%), Positives = 63/150 (42%), Gaps = 42/150 (28%)

Query: 320 LFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAK 379
           L G G+ G+RNLGN+C+LN+V+Q L S                    T P +DF      
Sbjct: 206 LLGSGHVGLRNLGNTCFLNAVLQCLSS--------------------TRPLRDF------ 239

Query: 380 LGHGLLSGEYSKPVPESGDGERVPE----------QKEVQDGIAPRMFKALIGKGHPEFS 429
                L  ++ + VP  G  + + E            +  + + P  F+A+  K  P FS
Sbjct: 240 ----CLRRDFRQEVPGGGRAQELTEAFADVIGALWHPDSCEAVNPTRFRAVFQKYVPSFS 295

Query: 430 TNRQQDAQEFFLHLINM--VERNCRSSENP 457
              QQDAQEF   L+    +E N R    P
Sbjct: 296 GYSQQDAQEFLKLLMERLHLEINRRGRRAP 325



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 31/121 (25%), Positives = 53/121 (43%), Gaps = 7/121 (5%)

Query: 739 DQALKALRATNN-SLERAVDWIFSHIDDLDAEAAMDISEGRSAADSISESVPVGPKVRDG 797
           D+  +  R+T   +++R    +  H++   A     I +     D   + + +G    D 
Sbjct: 438 DRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRG-SIKKSSVGVDFPLQRLSLGDFASDK 496

Query: 798 PGK--YQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKV--CASEKPPKDLGYIYFY 853
            G   YQL+A  +H G S   GHY    + +  W +YND +V   +  +     GY+ FY
Sbjct: 497 AGSPVYQLYALCNHSG-SVHYGHYTALCRCQTGWHVYNDSRVSPVSENQVASSEGYVLFY 555

Query: 854 Q 854
           Q
Sbjct: 556 Q 556


>gi|74027267 ubiquitin-specific protease 21 [Homo sapiens]
          Length = 565

 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 44/150 (29%), Positives = 63/150 (42%), Gaps = 42/150 (28%)

Query: 320 LFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAK 379
           L G G+ G+RNLGN+C+LN+V+Q L S                    T P +DF      
Sbjct: 206 LLGSGHVGLRNLGNTCFLNAVLQCLSS--------------------TRPLRDF------ 239

Query: 380 LGHGLLSGEYSKPVPESGDGERVPE----------QKEVQDGIAPRMFKALIGKGHPEFS 429
                L  ++ + VP  G  + + E            +  + + P  F+A+  K  P FS
Sbjct: 240 ----CLRRDFRQEVPGGGRAQELTEAFADVIGALWHPDSCEAVNPTRFRAVFQKYVPSFS 295

Query: 430 TNRQQDAQEFFLHLINM--VERNCRSSENP 457
              QQDAQEF   L+    +E N R    P
Sbjct: 296 GYSQQDAQEFLKLLMERLHLEINRRGRRAP 325



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 31/121 (25%), Positives = 53/121 (43%), Gaps = 7/121 (5%)

Query: 739 DQALKALRATNN-SLERAVDWIFSHIDDLDAEAAMDISEGRSAADSISESVPVGPKVRDG 797
           D+  +  R+T   +++R    +  H++   A     I +     D   + + +G    D 
Sbjct: 438 DRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRG-SIKKSSVGVDFPLQRLSLGDFASDK 496

Query: 798 PGK--YQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKV--CASEKPPKDLGYIYFY 853
            G   YQL+A  +H G S   GHY    + +  W +YND +V   +  +     GY+ FY
Sbjct: 497 AGSPVYQLYALCNHSG-SVHYGHYTALCRCQTGWHVYNDSRVSPVSENQVASSEGYVLFY 555

Query: 854 Q 854
           Q
Sbjct: 556 Q 556


>gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens]
          Length = 712

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 25/66 (37%), Positives = 44/66 (66%), Gaps = 6/66 (9%)

Query: 290 DKTMTELEIDMNQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPD 349
           DK ++  E +++Q++ +      S V  +P+  PG TG+RNLGN+CY+NSV+QVL  +  
Sbjct: 243 DKVLSTSENEISQKVSD------SSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLI 296

Query: 350 FQRKYV 355
           F++ ++
Sbjct: 297 FRQCFL 302



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 26/92 (28%), Positives = 49/92 (53%), Gaps = 11/92 (11%)

Query: 178 KHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHY 237
           KH   L+   + + + P  W C  C+  E++W  L+   + CG RY +      HA++H+
Sbjct: 8   KHVGQLQLAQDHSSLNPQKWHCVDCNTTESIWACLSCSHVACG-RYIE-----EHALKHF 61

Query: 238 RETGYPLAVKLGTITPDGADVYSYDEDDMVLD 269
           +E+ +P+A+++  +      V+ Y  DD VL+
Sbjct: 62  QESSHPVALEVNEMY-----VFCYLCDDYVLN 88



 Score = 37.0 bits (84), Expect = 0.078
 Identities = 24/61 (39%), Positives = 30/61 (49%), Gaps = 5/61 (8%)

Query: 801 YQLFAFISHMGTSTMCGHYV--CHIKKEGRWVIYNDQK--VCASEKPPKDLGYIYFY-QR 855
           Y L A + H G     GHY   C+  + G WV  ND K  +C  ++  K   YI FY QR
Sbjct: 619 YDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQR 678

Query: 856 V 856
           V
Sbjct: 679 V 679


>gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens]
          Length = 712

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 25/66 (37%), Positives = 44/66 (66%), Gaps = 6/66 (9%)

Query: 290 DKTMTELEIDMNQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPD 349
           DK ++  E +++Q++ +      S V  +P+  PG TG+RNLGN+CY+NSV+QVL  +  
Sbjct: 243 DKVLSTSENEISQKVSD------SSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLI 296

Query: 350 FQRKYV 355
           F++ ++
Sbjct: 297 FRQCFL 302



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 26/92 (28%), Positives = 49/92 (53%), Gaps = 11/92 (11%)

Query: 178 KHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHY 237
           KH   L+   + + + P  W C  C+  E++W  L+   + CG RY +      HA++H+
Sbjct: 8   KHVGQLQLAQDHSSLNPQKWHCVDCNTTESIWACLSCSHVACG-RYIE-----EHALKHF 61

Query: 238 RETGYPLAVKLGTITPDGADVYSYDEDDMVLD 269
           +E+ +P+A+++  +      V+ Y  DD VL+
Sbjct: 62  QESSHPVALEVNEMY-----VFCYLCDDYVLN 88



 Score = 37.0 bits (84), Expect = 0.078
 Identities = 24/61 (39%), Positives = 30/61 (49%), Gaps = 5/61 (8%)

Query: 801 YQLFAFISHMGTSTMCGHYV--CHIKKEGRWVIYNDQK--VCASEKPPKDLGYIYFY-QR 855
           Y L A + H G     GHY   C+  + G WV  ND K  +C  ++  K   YI FY QR
Sbjct: 619 YDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQR 678

Query: 856 V 856
           V
Sbjct: 679 V 679


>gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens]
          Length = 370

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 64/290 (22%), Positives = 106/290 (36%), Gaps = 36/290 (12%)

Query: 325 YTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGL 384
           Y G+ N GN+CY NSV+Q L+    F+ K +      +++ P    +   T +A L H +
Sbjct: 38  YFGLVNFGNTCYCNSVLQALYFCRPFREKVL-----AYKSQPR-KKESLLTCLADLFHSI 91

Query: 385 LSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLI 444
            +                  QK+    I P+ F   + K +  F    QQDA EF  +L+
Sbjct: 92  AT------------------QKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLL 133

Query: 445 NMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLE 504
           N +    +      +    L    I             VD I Q        L  E    
Sbjct: 134 NTIADILQEERKQEKQNGRLPNGNIDNENNNSTPDPTWVDEIFQ------GTLTNETRCL 187

Query: 505 YEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDD---FWSTALQAKSVAVKTTR 561
             E     +E+ + L   V      + CL  +   E +     ++    ++K  A K  +
Sbjct: 188 TCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMK 247

Query: 562 FASFPDYLVIQIKKFTFGLDWVPK--KLDVSIEMPEELDISQLRGTGLQP 609
               P  L + +K+F + +D + +  KL   +  P EL +    G    P
Sbjct: 248 VKKLPMILALHLKRFKY-MDQLHRYTKLSYRVVFPLELRLFNTSGDATNP 296



 Score = 33.9 bits (76), Expect = 0.66
 Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 14/68 (20%)

Query: 801 YQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYND---QKVCASE-----------KPPKD 846
           Y L A + H G+    GHY+  +K    W++++D   +K+ A                 +
Sbjct: 300 YDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSE 359

Query: 847 LGYIYFYQ 854
            GYI FYQ
Sbjct: 360 SGYILFYQ 367


>gi|21361749 ubiquitin thioesterase 49 [Homo sapiens]
          Length = 640

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 24/58 (41%), Positives = 36/58 (62%), Gaps = 4/58 (6%)

Query: 318 KPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVD----KLEKIFQNAPTDPTQ 371
           +P   PG TG+RNLGN+CY+NS++QVL  +  F+  +++    K E +F  A    TQ
Sbjct: 245 QPAMAPGVTGLRNLGNTCYMNSILQVLSHLQKFRECFLNLDPSKTEHLFPKATNGKTQ 302



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 23/71 (32%), Positives = 38/71 (53%), Gaps = 6/71 (8%)

Query: 178 KHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHY 237
           KH   L+   + + + P  W C +C   E++W  L    + CGR   D      HA++H+
Sbjct: 5   KHVGRLRLAQDHSILNPQKWCCLECATTESVWACLKCSHVACGRYIED------HALKHF 58

Query: 238 RETGYPLAVKL 248
            ETG+PLA+++
Sbjct: 59  EETGHPLAMEV 69


>gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens]
          Length = 963

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 36/125 (28%), Positives = 61/125 (48%), Gaps = 22/125 (17%)

Query: 323 PGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYV-DKLE-KIFQNAPTDPTQDFSTQVAKL 380
           PG  G+ NLGN+C++NS +Q L +       ++ D+ E +I ++ P     + +   A+L
Sbjct: 299 PGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAEL 358

Query: 381 GHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFF 440
              + SG  +                     +APRMFK  +G+  P+FS  +QQD+QE  
Sbjct: 359 IKQMWSGRDAH--------------------VAPRMFKTQVGRFAPQFSGYQQQDSQELL 398

Query: 441 LHLIN 445
             L++
Sbjct: 399 AFLLD 403



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 24/98 (24%), Positives = 46/98 (46%), Gaps = 7/98 (7%)

Query: 503 LEYEEKKRQAEEEKMAL---PELVRAQVPFSSCLEAYGAPEQV---DDFWSTALQAKSVA 556
           L Y+E++ +A E+ +++    +  +  V    C+E +   E +   D ++    +    A
Sbjct: 749 LYYDEQESEAYEKHVSMLQPQKKKKTTVALRDCIELFTTMETLGEHDPWYCPNCKKHQQA 808

Query: 557 VKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMP 594
            K     S P  LV+ +K+F++   W   KLD  +E P
Sbjct: 809 TKKFDLWSLPKILVVHLKRFSYNRYW-RDKLDTVVEFP 845


>gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens]
          Length = 916

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 36/125 (28%), Positives = 61/125 (48%), Gaps = 22/125 (17%)

Query: 323 PGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYV-DKLE-KIFQNAPTDPTQDFSTQVAKL 380
           PG  G+ NLGN+C++NS +Q L +       ++ D+ E +I ++ P     + +   A+L
Sbjct: 252 PGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAEL 311

Query: 381 GHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFF 440
              + SG  +                     +APRMFK  +G+  P+FS  +QQD+QE  
Sbjct: 312 IKQMWSGRDAH--------------------VAPRMFKTQVGRFAPQFSGYQQQDSQELL 351

Query: 441 LHLIN 445
             L++
Sbjct: 352 AFLLD 356



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 24/98 (24%), Positives = 46/98 (46%), Gaps = 7/98 (7%)

Query: 503 LEYEEKKRQAEEEKMAL---PELVRAQVPFSSCLEAYGAPEQV---DDFWSTALQAKSVA 556
           L Y+E++ +A E+ +++    +  +  V    C+E +   E +   D ++    +    A
Sbjct: 702 LYYDEQESEAYEKHVSMLQPQKKKKTTVALRDCIELFTTMETLGEHDPWYCPNCKKHQQA 761

Query: 557 VKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMP 594
            K     S P  LV+ +K+F++   W   KLD  +E P
Sbjct: 762 TKKFDLWSLPKILVVHLKRFSYNRYW-RDKLDTVVEFP 798


>gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]
          Length = 396

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 46/166 (27%), Positives = 70/166 (42%), Gaps = 27/166 (16%)

Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHG 383
           G  G+RNLGN+C++NS++Q L +  + +   + +L                  +  L HG
Sbjct: 56  GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRL-----------------YMRDLHHG 98

Query: 384 LLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHL 443
             S  ++  V E     +        D ++P  FK  I +  P F    QQDAQEF   L
Sbjct: 99  --SNAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFL 156

Query: 444 I----NMVER-NCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVD 484
           +    N V R   R   NP  +     +EK + +     KY +R D
Sbjct: 157 LDGLHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWR---KYLERED 199



 Score = 34.7 bits (78), Expect = 0.39
 Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 5/58 (8%)

Query: 801 YQLFAFISHMGTSTMCGHYV--CHIKKEGRWVIYNDQKV--CASEKPPKDLGYIYFYQ 854
           Y L+A  +H GT TM GHY   C     G W  +ND  V   +S +      Y+ FY+
Sbjct: 332 YNLYAVSNHSGT-TMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYE 388


>gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo
           sapiens]
          Length = 605

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 46/166 (27%), Positives = 70/166 (42%), Gaps = 27/166 (16%)

Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHG 383
           G  G+RNLGN+C++NS++Q L +  + +   + +L                  +  L HG
Sbjct: 265 GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRL-----------------YMRDLHHG 307

Query: 384 LLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHL 443
             S  ++  V E     +        D ++P  FK  I +  P F    QQDAQEF   L
Sbjct: 308 --SNAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFL 365

Query: 444 I----NMVER-NCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVD 484
           +    N V R   R   NP  +     +EK + +     KY +R D
Sbjct: 366 LDGLHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWR---KYLERED 408



 Score = 34.7 bits (78), Expect = 0.39
 Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 5/58 (8%)

Query: 801 YQLFAFISHMGTSTMCGHYV--CHIKKEGRWVIYNDQKV--CASEKPPKDLGYIYFYQ 854
           Y L+A  +H GT TM GHY   C     G W  +ND  V   +S +      Y+ FY+
Sbjct: 541 YNLYAVSNHSGT-TMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYE 597


>gi|57529246 ubiquitin thioesterase 19 [Homo sapiens]
          Length = 1318

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 50/218 (22%), Positives = 82/218 (37%), Gaps = 56/218 (25%)

Query: 310 IQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKL--EKIFQNAPT 367
           ++E     K +  PG+TG+ NLGN+C++NSV+Q L +  + +  + D+    +I  N P 
Sbjct: 481 VEEEEEEEKKVCLPGFTGLVNLGNTCFMNSVIQSLSNTRELRDFFHDRSFEAEINYNNPL 540

Query: 368 DPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPE 427
                 +   A L   L  G +                        P   KA++     +
Sbjct: 541 GTGGRLAIGFAVLLRALWKGTH--------------------HAFQPSKLKAIVASKASQ 580

Query: 428 FSTNRQQDAQEFFLHLINMVERNCRSSEN------------PNEV--------------- 460
           F+   Q DAQEF   L++ +  +    +N            P+EV               
Sbjct: 581 FTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRPDEVVAEEAWQRHKMRNDS 640

Query: 461 -----FRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPM 493
                F+   + K+ C    KV  T   D  + LPVP+
Sbjct: 641 FIVDLFQGQYKSKLVCPVCAKVSIT--FDPFLYLPVPL 676



 Score = 30.8 bits (68), Expect = 5.6
 Identities = 31/126 (24%), Positives = 55/126 (43%), Gaps = 11/126 (8%)

Query: 498  NKEELLEY---EEKKRQAEEEKMALPELVRA-QVPFSSCLEAYGAPEQV---DDFWSTAL 550
            N E L E+     K+ +  E+  +  E  RA       CL  +  PE +   + ++    
Sbjct: 1025 NNERLQEFVLVASKELECAEDPGSAGEAARAGHFTLDQCLNLFTRPEVLAPEEAWYCPQC 1084

Query: 551  QAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMP-EELDISQLRGTGLQP 609
            +    A K       P+ L++Q+K+F+F       K++  +E P   LD+S+     +  
Sbjct: 1085 KQHREASKQLLLWRLPNVLIVQLKRFSFRSFIWRDKINDLVEFPVRNLDLSKF---CIGQ 1141

Query: 610  GEEELP 615
             EE+LP
Sbjct: 1142 KEEQLP 1147


>gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]
          Length = 1352

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 39/147 (26%), Positives = 58/147 (39%), Gaps = 39/147 (26%)

Query: 323 PGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGH 382
           PG  G+RN GN+C++N+ +Q L +                       T+ F+  +A LG 
Sbjct: 125 PGVAGLRNHGNTCFMNATLQCLSN-----------------------TELFAEYLA-LGQ 160

Query: 383 GLLSGEYSKPVPESGDGERVPEQKEVQDGIA---------------PRMFKALIGKGHPE 427
                    P PE   G     Q EV + +A                R FK ++ K   +
Sbjct: 161 YRAGRPEPSPDPEQPAGRGAQGQGEVTEQLAHLVRALWTLEYTPQHSRDFKTIVSKNALQ 220

Query: 428 FSTNRQQDAQEFFLHLINMVERNCRSS 454
           +  N Q DAQEF L L++ V  +   S
Sbjct: 221 YRGNSQHDAQEFLLWLLDRVHEDLNHS 247


>gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo
           sapiens]
          Length = 359

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 55/257 (21%), Positives = 91/257 (35%), Gaps = 33/257 (12%)

Query: 325 YTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGL 384
           Y G+ N GN+CY NSV+Q L+    F+         +   A     ++  T +A L H +
Sbjct: 27  YFGLVNFGNTCYCNSVLQALYFCRPFRENV------LAYKAQQKKKENLLTCLADLFHSI 80

Query: 385 LSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLI 444
            +                  QK+    I P+ F + + K +  F    QQDA EF  +L+
Sbjct: 81  AT------------------QKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLL 122

Query: 445 NMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLE 504
           N +    +  +   +    L    +   A         V  I Q        L  E    
Sbjct: 123 NTIADILQEEKKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQ------GTLTNETRCL 176

Query: 505 YEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQV---DDFWSTALQAKSVAVKTTR 561
             E     +E+ + L   V      + CL  +   E +     ++     +K  A K  R
Sbjct: 177 NCETVSSKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMR 236

Query: 562 FASFPDYLVIQIKKFTF 578
               P  L + +K+F +
Sbjct: 237 VKKLPMILALHLKRFKY 253



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 14/68 (20%)

Query: 801 YQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYND---QKVCASE-----------KPPKD 846
           Y L A + H G+    GHY+  +K  G W++++D   +K+ A                 +
Sbjct: 289 YDLVAVVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSE 348

Query: 847 LGYIYFYQ 854
            GYI FYQ
Sbjct: 349 SGYILFYQ 356


>gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo
           sapiens]
          Length = 366

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 55/257 (21%), Positives = 91/257 (35%), Gaps = 33/257 (12%)

Query: 325 YTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGL 384
           Y G+ N GN+CY NSV+Q L+    F+         +   A     ++  T +A L H +
Sbjct: 34  YFGLVNFGNTCYCNSVLQALYFCRPFRENV------LAYKAQQKKKENLLTCLADLFHSI 87

Query: 385 LSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLI 444
            +                  QK+    I P+ F + + K +  F    QQDA EF  +L+
Sbjct: 88  AT------------------QKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLL 129

Query: 445 NMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLE 504
           N +    +  +   +    L    +   A         V  I Q        L  E    
Sbjct: 130 NTIADILQEEKKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQ------GTLTNETRCL 183

Query: 505 YEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQV---DDFWSTALQAKSVAVKTTR 561
             E     +E+ + L   V      + CL  +   E +     ++     +K  A K  R
Sbjct: 184 NCETVSSKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMR 243

Query: 562 FASFPDYLVIQIKKFTF 578
               P  L + +K+F +
Sbjct: 244 VKKLPMILALHLKRFKY 260



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 14/68 (20%)

Query: 801 YQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYND---QKVCASE-----------KPPKD 846
           Y L A + H G+    GHY+  +K  G W++++D   +K+ A                 +
Sbjct: 296 YDLVAVVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSE 355

Query: 847 LGYIYFYQ 854
            GYI FYQ
Sbjct: 356 SGYILFYQ 363


>gi|56550051 ubiquitin specific protease 39 [Homo sapiens]
          Length = 565

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 75/377 (19%), Positives = 151/377 (40%), Gaps = 71/377 (18%)

Query: 217 ILCGRRYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHL 276
           ++CG+ YF G G  +HA  H  +  + + + L T+       Y   ++  ++D SL E +
Sbjct: 137 LVCGK-YFQGRGLKSHAYIHSVQFSHHVFLNLHTLK-----FYCLPDNYEIIDSSL-EDI 189

Query: 277 SHFGIDMLKMQKTDKTMTELEIDMNQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCY 336
           ++    +LK   T + +  L+          +  + S       + PG  G+ N+  + Y
Sbjct: 190 TY----VLKPTFTKQQIANLD----------KQAKLSRAYDGTTYLPGIVGLNNIKANDY 235

Query: 337 LNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPES 396
            N+V+Q L ++P  +  +++  E  ++N    P       V + G  +            
Sbjct: 236 ANAVLQALSNVPPLRNYFLE--EDNYKNIKRPPGDIMFLLVQRFGELM------------ 281

Query: 397 GDGERVPEQKEVQDGIAP-RMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSE 455
               ++   +  +  ++P  M +A++      F   +Q D  +F    +N +      + 
Sbjct: 282 ---RKLWNPRNFKAHVSPHEMLQAVVLCSKKTFQITKQGDGVDFLSWFLNALHSALGGT- 337

Query: 456 NPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEE 515
                     ++K K + T+  + + R+ +  +LP P   A  KE+LL  +E +    E 
Sbjct: 338 ----------KKKKKTIVTDVFQGSMRI-FTKKLPHPDLPAEEKEQLLHNDEYQETMVES 386

Query: 516 -----KMALP----------ELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTT 560
                 + LP          +L+  QVP  + L  +    + +  + T    K   +K  
Sbjct: 387 TFMYLTLDLPTAPLYKDEKEQLIIPQVPLFNILAKFNGITEKE--YKT---YKENFLKRF 441

Query: 561 RFASFPDYLVIQIKKFT 577
           +    P YL+  IK+FT
Sbjct: 442 QLTKLPPYLIFCIKRFT 458


>gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens]
          Length = 963

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 31/125 (24%), Positives = 53/125 (42%), Gaps = 22/125 (17%)

Query: 323 PGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDK--LEKIFQNAPTDPTQDFSTQVAKL 380
           PG  G+ NLGN+C++NS +Q L ++P     +++   LE++    P     + +   A L
Sbjct: 306 PGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNCYLEELNFRNPLGMKGEIAEAYADL 365

Query: 381 GHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFF 440
                SG +                      I P +FK  +G    +F   +Q D+QE  
Sbjct: 366 VKQAWSGHHR--------------------SIVPHVFKNKVGHFASQFLGYQQHDSQELL 405

Query: 441 LHLIN 445
             L++
Sbjct: 406 SFLLD 410



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 8/98 (8%)

Query: 524 RAQVPFSSCLEAYGAPEQVDD---FWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGL 580
           +A V    C+E +   E ++    ++  + +   +A K       P+ L+I +K+F++  
Sbjct: 776 KAPVRLQECIELFTTVETLEKENPWYCPSCKQHQLATKKLDLWMLPEILIIHLKRFSY-T 834

Query: 581 DWVPKKLDVSIEMP-EELDISQLRGTGLQPGEEELPDI 617
            +  +KLD  +E P  +LD S+     +QP  E  P++
Sbjct: 835 KFSREKLDTLVEFPIRDLDFSEF---VIQPQNESNPEL 869


>gi|188497648 ubiquitin specific peptidase 37 [Homo sapiens]
          Length = 979

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 15/117 (12%)

Query: 744 ALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSAADSISESVPVGPKVRDGPGKYQL 803
           +L+  NNS    VD + S  +D   E   D+    + A+ +  +   G    + P  Y+L
Sbjct: 840 SLQEFNNSF---VDALGSD-EDSGNEDVFDMEYTEAEAEELKRNAETG----NLPHSYRL 891

Query: 804 FAFISHMGTSTMCGHYVCHIK--KEGRWVIYNDQKV-----CASEKPPKDLGYIYFY 853
            + +SH+G+++  GHY+  +   K+  W  YND +V      A +      GYI+FY
Sbjct: 892 ISVVSHIGSTSSSGHYISDVYDIKKQAWFTYNDLEVSKIQEAAVQSDRDRSGYIFFY 948



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 57/289 (19%), Positives = 111/289 (38%), Gaps = 30/289 (10%)

Query: 315 VPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFS 374
           VPL         G  NLGN+CY+N+++Q LFS+  F        + + Q  P       +
Sbjct: 330 VPLSSHQQQQLQGFSNLGNTCYMNAILQSLFSLQSFAN------DLLKQGIPWKKI-PLN 382

Query: 375 TQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQ 434
             + +  H L+  +                  E +  +  ++ K  I      FS   Q 
Sbjct: 383 ALIRRFAHLLVKKDIC--------------NSETKKDLLKKV-KNAISATAERFSGYMQN 427

Query: 435 DAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMD 494
           DA EF    ++ ++ +        +      EE    ++  +  YT  V  I  L   + 
Sbjct: 428 DAHEFLSQCLDQLKEDMEKLNKTWKTEPVSGEENSPDISATRA-YTCPV--ITNLEFEVQ 484

Query: 495 AALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFS--SCLEAYGAPEQVDDFWSTALQA 552
            ++  +   E   K+ Q  +  + LP   +   P S    L+ +   E+++  +S     
Sbjct: 485 HSIICKACGEIIPKREQFNDLSIDLPRRKKPLPPRSIQDSLDLFFRAEELE--YSCEKCG 542

Query: 553 KSVAVKTTRFASFPDYLVIQIKKFTFGLDW-VPKKLDVSIEMPEELDIS 600
              A+   +F   P  L++ +K+++F +   +  K+   + +P  L +S
Sbjct: 543 GKCALVRHKFNRLPRVLILHLKRYSFNVALSLNNKIGQQVIIPRYLTLS 591


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,961,381
Number of Sequences: 37866
Number of extensions: 1846850
Number of successful extensions: 6907
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 88
Number of HSP's successfully gapped in prelim test: 73
Number of HSP's that attempted gapping in prelim test: 6544
Number of HSP's gapped (non-prelim): 391
length of query: 858
length of database: 18,247,518
effective HSP length: 111
effective length of query: 747
effective length of database: 14,044,392
effective search space: 10491160824
effective search space used: 10491160824
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.